locus-tag	class	description
HEQ83_RS00010	COG0592	DNA-directed DNA polymerase activity
HEQ83_RS00015	COG2501	S4 domain
HEQ83_RS00030	COG0187	DNA topoisomerase II activity
HEQ83_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEQ83_RS00070	COG0516	GMP reductase activity
HEQ83_RS00070	COG0517	IMP dehydrogenase activity
HEQ83_RS00075	COG1686	Belongs to the peptidase S11 family
HEQ83_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
HEQ83_RS00105	COG1428	Deoxynucleoside kinase
HEQ83_RS00110	COG1428	Deoxynucleoside kinase
HEQ83_RS00115	COG1388	LysM domain
HEQ83_RS00115	COG3858	chitin binding
HEQ83_RS00120	COG1335	isochorismatase
HEQ83_RS00125	COG0590	tRNA wobble adenosine to inosine editing
HEQ83_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEQ83_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEQ83_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEQ83_RS00195	COG3853	Toxic anion resistance protein (TelA)
HEQ83_RS00200	COG1982	Orn Lys Arg decarboxylase major
HEQ83_RS00210	COG3870	Protein conserved in bacteria
HEQ83_RS00215	COG1728	Protein conserved in bacteria
HEQ83_RS00220	COG0470	DNA polymerase III
HEQ83_RS00225	COG1774	PSP1 C-terminal conserved region
HEQ83_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HEQ83_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEQ83_RS00250	COG2002	toxin-antitoxin pair type II binding
HEQ83_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEQ83_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEQ83_RS00260	COG0084	hydrolase, TatD family'
HEQ83_RS00265	COG3584	3D domain protein
HEQ83_RS00265	COG3583	domain protein
HEQ83_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEQ83_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HEQ83_RS00285	COG4466	Protein conserved in bacteria
HEQ83_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEQ83_RS00305	COG0251	oxidation-reduction process
HEQ83_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEQ83_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEQ83_RS00345	COG2002	toxin-antitoxin pair type II binding
HEQ83_RS00350	COG2244	polysaccharide biosynthetic process
HEQ83_RS00355	COG3956	TIGRFAM MazG family protein
HEQ83_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HEQ83_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HEQ83_RS00380	COG1098	S1 RNA binding domain
HEQ83_RS00395	COG2208	phosphoserine phosphatase activity
HEQ83_RS00400	COG2304	oxidoreductase activity
HEQ83_RS00405	COG0515	serine threonine protein kinase
HEQ83_RS00410	COG0037	tRNA processing
HEQ83_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEQ83_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HEQ83_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HEQ83_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEQ83_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
HEQ83_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HEQ83_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEQ83_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEQ83_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEQ83_RS00475	COG1396	sequence-specific DNA binding
HEQ83_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEQ83_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HEQ83_RS00565	COG4463	regulation of RNA biosynthetic process
HEQ83_RS00570	COG3880	PFAM UvrB UvrC protein
HEQ83_RS00580	COG0542	response to heat
HEQ83_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEQ83_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HEQ83_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
HEQ83_RS00615	COG1045	serine acetyltransferase
HEQ83_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEQ83_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEQ83_RS00635	COG3688	RNA-binding protein containing a PIN domain
HEQ83_RS00640	COG1595	DNA-templated transcription, initiation
HEQ83_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HEQ83_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
HEQ83_RS00680	COG2813	Specifically methylates the guanine in position
HEQ83_RS00695	COG1358	cellular component organization or biogenesis
HEQ83_RS00720	COG0596	Alpha beta hydrolase
HEQ83_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEQ83_RS00830	COG0201	protein transport
HEQ83_RS00840	COG0024	Methionine aminopeptidase
HEQ83_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HEQ83_RS00880	COG1122	ATPase activity
HEQ83_RS00885	COG1122	ATPase activity
HEQ83_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEQ83_RS00910	COG2226	methyltransferase
HEQ83_RS00915	COG2318	DinB family
HEQ83_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
HEQ83_RS00930	COG0489	protein tyrosine kinase activity
HEQ83_RS00940	COG2194	sulfuric ester hydrolase activity
HEQ83_RS00945	COG0726	polysaccharide deacetylase
HEQ83_RS01005	COG0738	Major facilitator superfamily
HEQ83_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
HEQ83_RS01030	COG0385	Bile acid
HEQ83_RS01035	COG2819	hydrolase of the alpha beta superfamily
HEQ83_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEQ83_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEQ83_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HEQ83_RS01055	COG2207	Transcriptional regulator
HEQ83_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HEQ83_RS01060	COG3876	Protein conserved in bacteria
HEQ83_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
HEQ83_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HEQ83_RS01075	COG1263	PTS System
HEQ83_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEQ83_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEQ83_RS01090	COG1683	Conserved Protein
HEQ83_RS01120	COG1595	DNA-templated transcription, initiation
HEQ83_RS01125	COG5662	AntiSigma factor
HEQ83_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEQ83_RS01135	COG4856	YbbR-like protein
HEQ83_RS01175	COG1346	cytolysis
HEQ83_RS01180	COG1380	Effector of murein hydrolase LrgA
HEQ83_RS01185	COG1846	Transcriptional regulator
HEQ83_RS01190	COG1113	amino acid transport
HEQ83_RS01195	COG1011	Hydrolase
HEQ83_RS01200	COG4585	Histidine kinase
HEQ83_RS01205	COG2197	response regulator
HEQ83_RS01210	COG1131	(ABC) transporter
HEQ83_RS01250	COG0531	amino acid
HEQ83_RS01255	COG0584	glycerophosphoryl diester phosphodiesterase
HEQ83_RS01260	COG2271	Major facilitator Superfamily
HEQ83_RS01270	COG2368	4-hydroxyphenylacetate
HEQ83_RS01280	COG3409	Peptidoglycan-binding domain 1 protein
HEQ83_RS01295	COG0371	Dehydrogenase
HEQ83_RS01305	COG1183	phosphatidylcholine synthase activity
HEQ83_RS01310	COG0586	Pfam SNARE associated Golgi protein
HEQ83_RS01315	COG0688	phosphatidylethanolamine metabolic process
HEQ83_RS01330	COG1301	dicarboxylic acid transport
HEQ83_RS01335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HEQ83_RS01340	COG0833	amino acid
HEQ83_RS01345	COG2040	homocysteine
HEQ83_RS01350	COG1115	amino acid carrier protein
HEQ83_RS01355	COG2066	Belongs to the glutaminase family
HEQ83_RS01360	COG4191	Histidine kinase
HEQ83_RS01365	COG0784	Response regulator, receiver
HEQ83_RS01370	COG3173	Aminoglycoside phosphotransferase
HEQ83_RS01380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEQ83_RS01385	COG0778	Nitroreductase
HEQ83_RS01390	COG0346	lactoylglutathione lyase activity
HEQ83_RS01395	COG2259	Doxx family
HEQ83_RS01400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEQ83_RS01415	COG3773	Cell wall hydrolase
HEQ83_RS01420	COG3540	Alkaline phosphatase
HEQ83_RS01425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEQ83_RS01430	COG0805	protein transport
HEQ83_RS01440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEQ83_RS01445	COG0477	Major facilitator Superfamily
HEQ83_RS01450	COG1309	transcriptional regulator
HEQ83_RS01455	COG0252	asparaginase activity
HEQ83_RS01460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEQ83_RS01465	COG3012	SEC-C Motif Domain Protein
HEQ83_RS01465	COG1405	negative regulation of cell septum assembly
HEQ83_RS01470	COG0667	Aldo Keto reductase
HEQ83_RS01480	COG1595	DNA-templated transcription, initiation
HEQ83_RS01485	COG1595	DNA-templated transcription, initiation
HEQ83_RS01490	COG1876	peptidase activity
HEQ83_RS01495	COG0457	Tetratricopeptide repeat
HEQ83_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS01505	COG0366	Alpha amylase catalytic
HEQ83_RS01510	COG0803	Belongs to the bacterial solute-binding protein 9 family
HEQ83_RS01515	COG1121	(ABC) transporter
HEQ83_RS01520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HEQ83_RS01525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEQ83_RS01530	COG2310	stress, protein
HEQ83_RS01535	COG2310	stress, protein
HEQ83_RS01540	COG2310	stress, protein
HEQ83_RS01545	COG0861	Integral membrane protein TerC family
HEQ83_RS01555	COG3853	Toxic anion resistance protein (TelA)
HEQ83_RS01560	COG0477	Major facilitator Superfamily
HEQ83_RS01565	COG4175	Glycine betaine
HEQ83_RS01565	COG0517	IMP dehydrogenase activity
HEQ83_RS01570	COG4176	ABC-type proline glycine betaine transport system permease component
HEQ83_RS01575	COG2113	Glycine betaine
HEQ83_RS01580	COG1473	amidohydrolase
HEQ83_RS01585	COG1288	antiporter activity
HEQ83_RS01595	COG0366	Alpha amylase catalytic
HEQ83_RS01605	COG2814	Major facilitator Superfamily
HEQ83_RS01610	COG1846	Transcriptional regulator
HEQ83_RS01615	COG1280	lysine exporter protein (LysE YggA)
HEQ83_RS01620	COG3403	YqcI/YcgG family
HEQ83_RS01625	COG1113	amino acid transport
HEQ83_RS01630	COG3665	Urea carboxylase-associated protein
HEQ83_RS01645	COG1660	Displays ATPase and GTPase activities
HEQ83_RS01655	COG2271	Major facilitator Superfamily
HEQ83_RS01660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEQ83_RS01665	COG3458	cephalosporin-C deacetylase activity
HEQ83_RS01670	COG3541	Predicted nucleotidyltransferase
HEQ83_RS01675	COG0506	proline dehydrogenase activity
HEQ83_RS01680	COG1012	belongs to the aldehyde dehydrogenase family
HEQ83_RS01690	COG2508	Transcriptional regulator
HEQ83_RS01700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HEQ83_RS01700	COG1587	Uroporphyrinogen-III synthase
HEQ83_RS01705	COG2146	nitrite reductase [NAD(P)H] activity
HEQ83_RS01710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEQ83_RS01715	COG0523	cobalamin synthesis protein
HEQ83_RS01720	COG1063	alcohol dehydrogenase
HEQ83_RS01725	COG1714	RDD family
HEQ83_RS01735	COG2723	6-phospho-beta-galactosidase activity
HEQ83_RS01750	COG3209	COG3209 Rhs family protein
HEQ83_RS01755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HEQ83_RS01760	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HEQ83_RS01765	COG1733	regulation of RNA biosynthetic process
HEQ83_RS01770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS01780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS01785	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HEQ83_RS01800	COG2364	Membrane
HEQ83_RS01805	COG1126	abc transporter atp-binding protein
HEQ83_RS01810	COG0765	amino acid transport
HEQ83_RS01815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEQ83_RS01820	COG0583	DNA-binding transcription factor activity
HEQ83_RS01825	COG0163	prenyltransferase activity
HEQ83_RS01830	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HEQ83_RS01845	COG3104	oligopeptide transport
HEQ83_RS01850	COG5434	Belongs to the glycosyl hydrolase 28 family
HEQ83_RS01860	COG0697	spore germination
HEQ83_RS01870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HEQ83_RS01875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEQ83_RS01880	COG0456	acetyltransferase
HEQ83_RS01885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEQ83_RS01890	COG0765	amino acid transport
HEQ83_RS01895	COG1126	abc transporter atp-binding protein
HEQ83_RS01900	COG1473	amidohydrolase
HEQ83_RS01905	COG2079	MmgE PrpD family protein
HEQ83_RS01910	COG1136	(ABC) transporter
HEQ83_RS01915	COG0577	efflux transmembrane transporter activity
HEQ83_RS01920	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS01925	COG5002	protein histidine kinase activity
HEQ83_RS01925	COG3850	Histidine kinase
HEQ83_RS01930	COG0457	Tetratricopeptide repeat
HEQ83_RS01945	COG0527	aspartate kinase activity
HEQ83_RS01950	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEQ83_RS01955	COG4605	iron ion homeostasis
HEQ83_RS01960	COG4604	ABC transporter, ATP-binding protein
HEQ83_RS01965	COG4607	ABC-type enterochelin transport system periplasmic component
HEQ83_RS01970	COG2814	Major facilitator Superfamily
HEQ83_RS01975	COG1309	transcriptional regulator
HEQ83_RS01980	COG0778	Nitroreductase
HEQ83_RS01985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HEQ83_RS01990	COG0640	Transcriptional regulator
HEQ83_RS01995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEQ83_RS02000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEQ83_RS02005	COG1012	belongs to the aldehyde dehydrogenase family
HEQ83_RS02010	COG4975	Glucose uptake
HEQ83_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS02020	COG4549	nuclear export factor GLE1
HEQ83_RS02025	COG1276	copper resistance
HEQ83_RS02025	COG2372	response to copper ion
HEQ83_RS02030	COG1349	DNA-binding transcription factor activity
HEQ83_RS02040	COG2213	PTS system mannitol-specific
HEQ83_RS02045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEQ83_RS02055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HEQ83_RS02065	COG0561	phosphatase activity
HEQ83_RS02075	COG1914	H( )-stimulated, divalent metal cation uptake system
HEQ83_RS02085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HEQ83_RS02090	COG1984	allophanate hydrolase subunit 2
HEQ83_RS02095	COG1414	Transcriptional regulator
HEQ83_RS02100	COG2755	lipolytic protein G-D-S-L family
HEQ83_RS02110	COG2329	Antibiotic biosynthesis monooxygenase
HEQ83_RS02115	COG0768	penicillin binding
HEQ83_RS02120	COG4989	oxidoreductase activity
HEQ83_RS02125	COG3711	transcriptional antiterminator
HEQ83_RS02130	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS02140	COG1917	Cupin 2, conserved barrel domain protein
HEQ83_RS02145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEQ83_RS02150	COG3871	stress protein (general stress protein 26)
HEQ83_RS02160	COG2814	Major facilitator Superfamily
HEQ83_RS02165	COG1522	sequence-specific DNA binding
HEQ83_RS02170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEQ83_RS02170	COG0551	DNA topoisomerase type I activity
HEQ83_RS02175	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEQ83_RS02180	COG3706	GGDEF domain
HEQ83_RS02185	COG5298	Protein conserved in bacteria
HEQ83_RS02190	COG1215	transferase activity, transferring glycosyl groups
HEQ83_RS02200	COG0531	amino acid
HEQ83_RS02205	COG0494	nUDIX hydrolase
HEQ83_RS02210	COG0028	Belongs to the TPP enzyme family
HEQ83_RS02265	COG0457	Tetratricopeptide repeat
HEQ83_RS02290	COG1914	H( )-stimulated, divalent metal cation uptake system
HEQ83_RS02300	COG4876	unkown
HEQ83_RS02310	COG2076	Multidrug Resistance protein
HEQ83_RS02315	COG2217	Heavy metal translocating P-type atpase
HEQ83_RS02320	COG3729	General stress protein
HEQ83_RS02325	COG0662	Cupin 2, conserved barrel domain protein
HEQ83_RS02330	COG2329	Antibiotic biosynthesis monooxygenase
HEQ83_RS02335	COG3546	catalase activity
HEQ83_RS02340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HEQ83_RS02345	COG3290	protein histidine kinase activity
HEQ83_RS02350	COG4565	transcriptional regulatory protein
HEQ83_RS02355	COG1301	dicarboxylic acid transport
HEQ83_RS02360	COG0628	permease
HEQ83_RS02365	COG1131	(ABC) transporter
HEQ83_RS02370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HEQ83_RS02380	COG1960	acyl-CoA dehydrogenase activity
HEQ83_RS02395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEQ83_RS02400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEQ83_RS02410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HEQ83_RS02415	COG0513	Belongs to the DEAD box helicase family
HEQ83_RS02420	COG3402	PFAM membrane-flanked domain
HEQ83_RS02425	COG3428	Bacterial PH domain
HEQ83_RS02430	COG0705	Rhomboid family
HEQ83_RS02440	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HEQ83_RS02445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEQ83_RS02450	COG0864	Transcriptional regulator
HEQ83_RS02455	COG2337	Toxic component of a toxin-antitoxin (TA) module
HEQ83_RS02460	COG1366	Belongs to the anti-sigma-factor antagonist family
HEQ83_RS02465	COG1366	Belongs to the anti-sigma-factor antagonist family
HEQ83_RS02470	COG2172	sigma factor antagonist activity
HEQ83_RS02475	COG2208	phosphoserine phosphatase activity
HEQ83_RS02480	COG1366	Belongs to the anti-sigma-factor antagonist family
HEQ83_RS02490	COG1191	sigma factor activity
HEQ83_RS02495	COG2208	phosphoserine phosphatase activity
HEQ83_RS02500	COG2183	response to ionizing radiation
HEQ83_RS02590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HEQ83_RS02595	COG0477	Major facilitator Superfamily
HEQ83_RS02605	COG1764	response to oxidative stress
HEQ83_RS02610	COG1846	Transcriptional regulator
HEQ83_RS02620	COG1959	2 iron, 2 sulfur cluster binding
HEQ83_RS02625	COG2910	NAD(P)H-binding
HEQ83_RS02630	COG1278	Cold shock
HEQ83_RS02640	COG1937	Protein conserved in bacteria
HEQ83_RS02645	COG2210	Belongs to the sulfur carrier protein TusA family
HEQ83_RS02655	COG0425	Belongs to the sulfur carrier protein TusA family
HEQ83_RS02655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEQ83_RS02660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEQ83_RS02660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEQ83_RS02665	COG0425	Belongs to the sulfur carrier protein TusA family
HEQ83_RS02670	COG0730	response to heat
HEQ83_RS02675	COG1794	racemase activity, acting on amino acids and derivatives
HEQ83_RS02690	COG3621	Patatin-like phospholipase
HEQ83_RS02700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEQ83_RS02705	COG1802	Transcriptional regulator
HEQ83_RS02710	COG0251	oxidation-reduction process
HEQ83_RS02715	COG0814	amino acid
HEQ83_RS02720	COG1473	amidohydrolase
HEQ83_RS02725	COG2207	Transcriptional regulator
HEQ83_RS02725	COG1917	Cupin 2, conserved barrel domain protein
HEQ83_RS02735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEQ83_RS02740	COG0477	Major facilitator Superfamily
HEQ83_RS02760	COG0277	FAD linked oxidase domain protein
HEQ83_RS02790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEQ83_RS02815	COG1064	alcohol dehydrogenase
HEQ83_RS02820	COG0789	Transcriptional regulator
HEQ83_RS02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEQ83_RS02845	COG2814	Major facilitator Superfamily
HEQ83_RS02850	COG1309	transcriptional regulator
HEQ83_RS02855	COG5577	PFAM Coat F domain
HEQ83_RS02865	COG1063	alcohol dehydrogenase
HEQ83_RS02870	COG5577	PFAM Coat F domain
HEQ83_RS02880	COG4585	Histidine kinase
HEQ83_RS02885	COG2197	response regulator
HEQ83_RS02890	COG2409	Drug exporters of the RND superfamily
HEQ83_RS02895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HEQ83_RS02905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEQ83_RS02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEQ83_RS02920	COG2814	Major facilitator Superfamily
HEQ83_RS02925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HEQ83_RS02935	COG0730	response to heat
HEQ83_RS02940	COG0456	acetyltransferase
HEQ83_RS02945	COG4978	Transcriptional regulator
HEQ83_RS02945	COG0789	Transcriptional regulator
HEQ83_RS02950	COG0697	spore germination
HEQ83_RS02955	COG1051	belongs to the nudix hydrolase family
HEQ83_RS02960	COG2226	methyltransferase
HEQ83_RS02965	COG0473	3-isopropylmalate dehydrogenase activity
HEQ83_RS02970	COG1802	Transcriptional regulator
HEQ83_RS02975	COG1819	glycosyl
HEQ83_RS02990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HEQ83_RS03000	COG1388	LysM domain
HEQ83_RS03005	COG2814	Major facilitator Superfamily
HEQ83_RS03010	COG2188	Transcriptional regulator
HEQ83_RS03015	COG2186	Transcriptional regulator
HEQ83_RS03020	COG2807	transmembrane transport
HEQ83_RS03025	COG2076	Multidrug Resistance protein
HEQ83_RS03030	COG2076	Multidrug Resistance protein
HEQ83_RS03035	COG1309	transcriptional regulator
HEQ83_RS03040	COG0531	amino acid
HEQ83_RS03050	COG3832	glyoxalase III activity
HEQ83_RS03055	COG0604	alcohol dehydrogenase
HEQ83_RS03060	COG2814	Major facilitator Superfamily
HEQ83_RS03100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEQ83_RS03105	COG0802	atpase or kinase
HEQ83_RS03110	COG1214	PFAM Peptidase M22, glycoprotease
HEQ83_RS03115	COG0456	acetyltransferase
HEQ83_RS03120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEQ83_RS03125	COG0488	(ABC) transporter
HEQ83_RS03140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEQ83_RS03145	COG0805	protein transport
HEQ83_RS03155	COG1266	CAAX protease self-immunity
HEQ83_RS03215	COG1131	(ABC) transporter
HEQ83_RS03220	COG0842	Transport permease protein
HEQ83_RS03225	COG0457	Tetratricopeptide repeat
HEQ83_RS03230	COG1063	alcohol dehydrogenase
HEQ83_RS03235	COG2211	Major facilitator Superfamily
HEQ83_RS03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEQ83_RS03250	COG1842	Phage shock protein A
HEQ83_RS03255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEQ83_RS03260	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HEQ83_RS03265	COG4260	virion core protein, lumpy skin disease virus
HEQ83_RS03270	COG2755	lipolytic protein G-D-S-L family
HEQ83_RS03270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HEQ83_RS03280	COG1595	DNA-templated transcription, initiation
HEQ83_RS03285	COG1063	alcohol dehydrogenase
HEQ83_RS03290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEQ83_RS03295	COG0823	Involved in the tonB-independent uptake of proteins
HEQ83_RS03310	COG2132	Multicopper oxidase
HEQ83_RS03315	COG1113	amino acid transport
HEQ83_RS03320	COG0714	Associated with various cellular activities
HEQ83_RS03325	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HEQ83_RS03330	COG1305	Transglutaminase-like
HEQ83_RS03350	COG2252	PERMEase
HEQ83_RS03355	COG3064	Membrane
HEQ83_RS03375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEQ83_RS03380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEQ83_RS03385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEQ83_RS03390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HEQ83_RS03395	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEQ83_RS03410	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEQ83_RS03420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEQ83_RS03425	COG0138	bifunctional purine biosynthesis protein purh
HEQ83_RS03430	COG0151	Belongs to the GarS family
HEQ83_RS03440	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEQ83_RS03445	COG1470	cell adhesion involved in biofilm formation
HEQ83_RS03450	COG4496	protein, YerC YecD
HEQ83_RS03455	COG0069	glutamate synthase activity
HEQ83_RS03465	COG0210	DNA helicase
HEQ83_RS03475	COG4851	CamS sex pheromone cAM373 precursor
HEQ83_RS03480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEQ83_RS03485	COG1285	pathogenesis
HEQ83_RS03490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEQ83_RS03510	COG1309	transcriptional regulator
HEQ83_RS03515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEQ83_RS03520	COG1597	lipid kinase activity
HEQ83_RS03525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEQ83_RS03535	COG1131	(ABC) transporter
HEQ83_RS03560	COG5444	nuclease activity
HEQ83_RS03595	COG3546	catalase activity
HEQ83_RS03600	COG0454	-acetyltransferase
HEQ83_RS03610	COG2323	membrane
HEQ83_RS03615	COG2329	Antibiotic biosynthesis monooxygenase
HEQ83_RS03620	COG0346	lactoylglutathione lyase activity
HEQ83_RS03625	COG1366	Belongs to the anti-sigma-factor antagonist family
HEQ83_RS03630	COG5583	Uncharacterized small protein (DUF2292)
HEQ83_RS03635	COG0196	riboflavin kinase activity
HEQ83_RS03640	COG0670	Belongs to the BI1 family
HEQ83_RS03650	COG1846	Transcriptional regulator
HEQ83_RS03655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HEQ83_RS03665	COG2124	cytochrome p450
HEQ83_RS03665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEQ83_RS03670	COG1368	sulfuric ester hydrolase activity
HEQ83_RS03675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HEQ83_RS03680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEQ83_RS03685	COG1442	glycosyl transferase family 8
HEQ83_RS03690	COG1216	Glycosyl transferase, family 2
HEQ83_RS03695	COG1442	glycosyl transferase family 8
HEQ83_RS03700	COG2223	nitrite transmembrane transporter activity
HEQ83_RS03705	COG0531	amino acid
HEQ83_RS03710	COG1012	belongs to the aldehyde dehydrogenase family
HEQ83_RS03715	COG0840	transmembrane signaling receptor activity
HEQ83_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS03725	COG0457	Tetratricopeptide repeat
HEQ83_RS03725	COG0463	Glycosyl transferase, family 2
HEQ83_RS03730	COG0488	(ABC) transporter
HEQ83_RS03735	COG0789	Transcriptional regulator
HEQ83_RS03740	COG2814	Major facilitator Superfamily
HEQ83_RS03745	COG0488	(ABC) transporter
HEQ83_RS03750	COG0513	Belongs to the DEAD box helicase family
HEQ83_RS03760	COG2130	NADP-dependent
HEQ83_RS03775	COG3866	Pectate lyase
HEQ83_RS03780	COG0471	metal ion transport
HEQ83_RS03805	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS03805	COG2972	Histidine kinase
HEQ83_RS03810	COG3279	Response regulator of the LytR AlgR family
HEQ83_RS03820	COG3764	Sortase (surface protein transpeptidase)
HEQ83_RS03825	COG3290	protein histidine kinase activity
HEQ83_RS03830	COG4565	transcriptional regulatory protein
HEQ83_RS03835	COG3181	Tripartite tricarboxylate transporter family receptor
HEQ83_RS03840	COG2851	Citrate transporter
HEQ83_RS03845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEQ83_RS03850	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HEQ83_RS03860	COG2258	MOSC domain
HEQ83_RS03880	COG0024	Methionine aminopeptidase
HEQ83_RS03885	COG1263	PTS System
HEQ83_RS03885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEQ83_RS03895	COG1368	sulfuric ester hydrolase activity
HEQ83_RS03905	COG0071	Belongs to the small heat shock protein (HSP20) family
HEQ83_RS03920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEQ83_RS03920	COG1263	PTS System
HEQ83_RS03925	COG0366	Alpha amylase catalytic
HEQ83_RS03930	COG2188	Transcriptional regulator
HEQ83_RS03935	COG0778	Nitroreductase
HEQ83_RS03950	COG0737	Belongs to the 5'-nucleotidase family
HEQ83_RS03955	COG0693	protein deglycase activity
HEQ83_RS03960	COG1609	Transcriptional regulator
HEQ83_RS03975	COG2814	Major facilitator Superfamily
HEQ83_RS03985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEQ83_RS03990	COG4980	gas vesicle protein
HEQ83_RS03995	COG1295	ribonuclease BN
HEQ83_RS04000	COG0477	Major facilitator Superfamily
HEQ83_RS04005	COG0387	Pfam Sodium calcium exchanger
HEQ83_RS04015	COG0668	transmembrane transport
HEQ83_RS04020	COG0535	radical SAM domain protein
HEQ83_RS04030	COG0726	polysaccharide deacetylase
HEQ83_RS04035	COG2084	Dehydrogenase
HEQ83_RS04045	COG0598	Magnesium transport protein CorA
HEQ83_RS04050	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEQ83_RS04055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEQ83_RS04065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEQ83_RS04070	COG4637	Psort location Cytoplasmic, score
HEQ83_RS04075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HEQ83_RS04080	COG0022	dehydrogenase e1 component
HEQ83_RS04085	COG0508	dehydrogenase complex catalyzes the overall conversion of
HEQ83_RS04090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEQ83_RS04095	COG3284	Transcriptional regulator
HEQ83_RS04105	COG1486	melibiose metabolic process
HEQ83_RS04110	COG1737	Transcriptional regulator
HEQ83_RS04115	COG1263	PTS System
HEQ83_RS04115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEQ83_RS04120	COG1132	(ABC) transporter
HEQ83_RS04125	COG1132	(ABC) transporter
HEQ83_RS04130	COG2259	Doxx family
HEQ83_RS04135	COG2514	catechol 2,3-dioxygenase activity
HEQ83_RS04145	COG1695	Transcriptional regulator
HEQ83_RS04150	COG2249	NAD(P)H dehydrogenase (quinone) activity
HEQ83_RS04155	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HEQ83_RS04160	COG3848	Pyruvate phosphate dikinase
HEQ83_RS04160	COG0574	Belongs to the PEP-utilizing enzyme family
HEQ83_RS04165	COG2732	(Barnase) inhibitor
HEQ83_RS04170	COG2318	DinB family
HEQ83_RS04175	COG2814	Major facilitator Superfamily
HEQ83_RS04180	COG1846	Transcriptional regulator
HEQ83_RS04185	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEQ83_RS04185	COG0392	lysyltransferase activity
HEQ83_RS04190	COG0384	phenazine biosynthesis protein PhzF
HEQ83_RS04195	COG0778	Nitroreductase
HEQ83_RS04210	COG1090	epimerase
HEQ83_RS04225	COG2814	Major facilitator Superfamily
HEQ83_RS04235	COG3591	Belongs to the peptidase S1B family
HEQ83_RS04250	COG3103	Sh3 type 3 domain protein
HEQ83_RS04255	COG5658	integral membrane protein
HEQ83_RS04260	COG0596	Alpha beta hydrolase
HEQ83_RS04265	COG0463	Glycosyl transferase, family 2
HEQ83_RS04270	COG4485	Bacterial membrane protein, YfhO
HEQ83_RS04275	COG1988	membrane-bound metal-dependent
HEQ83_RS04280	COG1194	a g-specific adenine glycosylase
HEQ83_RS04290	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS04310	COG1132	(ABC) transporter
HEQ83_RS04315	COG4129	membrane
HEQ83_RS04325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEQ83_RS04330	COG0735	belongs to the Fur family
HEQ83_RS04445	COG3340	Belongs to the peptidase S51 family
HEQ83_RS04455	COG0277	FAD linked oxidase domain protein
HEQ83_RS04465	COG0747	negative chemotaxis
HEQ83_RS04470	COG0601	transmembrane transport
HEQ83_RS04475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEQ83_RS04480	COG0444	Belongs to the ABC transporter superfamily
HEQ83_RS04485	COG4608	Belongs to the ABC transporter superfamily
HEQ83_RS04490	COG0753	catalase activity
HEQ83_RS04500	COG1116	anion transmembrane transporter activity
HEQ83_RS04505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HEQ83_RS04510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HEQ83_RS04530	COG1476	TRANSCRIPTIONal
HEQ83_RS04540	COG3382	B3 4 domain protein
HEQ83_RS04545	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEQ83_RS04555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HEQ83_RS04560	COG0789	Transcriptional regulator
HEQ83_RS04565	COG1664	Polymer-forming cytoskeletal
HEQ83_RS04570	COG1664	Polymer-forming cytoskeletal
HEQ83_RS04575	COG2766	serine protein kinase
HEQ83_RS04585	COG1846	Transcriptional regulator
HEQ83_RS04590	COG1566	PFAM secretion protein HlyD family protein
HEQ83_RS04595	COG2814	Major facilitator Superfamily
HEQ83_RS04600	COG0655	NAD(P)H dehydrogenase (quinone) activity
HEQ83_RS04615	COG1725	Transcriptional regulator
HEQ83_RS04620	COG1131	(ABC) transporter
HEQ83_RS04625	COG1131	(ABC) transporter
HEQ83_RS04630	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HEQ83_RS04635	COG1278	Cold shock
HEQ83_RS04640	COG1464	Belongs to the NlpA lipoprotein family
HEQ83_RS04645	COG3706	GGDEF domain
HEQ83_RS04650	COG1823	symporter activity
HEQ83_RS04670	COG5577	PFAM Coat F domain
HEQ83_RS04680	COG3764	Sortase (surface protein transpeptidase)
HEQ83_RS04685	COG0564	pseudouridine synthase activity
HEQ83_RS04695	COG0517	IMP dehydrogenase activity
HEQ83_RS04700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HEQ83_RS04705	COG3153	acetyltransferase
HEQ83_RS04705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HEQ83_RS04710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HEQ83_RS04715	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HEQ83_RS04720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HEQ83_RS04730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEQ83_RS04735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEQ83_RS04740	COG2203	Gaf domain
HEQ83_RS04740	COG4585	Histidine kinase
HEQ83_RS04745	COG2197	response regulator
HEQ83_RS04750	COG0431	NADPH-dependent FMN reductase
HEQ83_RS04765	COG0791	NLP P60 protein
HEQ83_RS04765	COG1388	LysM domain
HEQ83_RS04770	COG1959	2 iron, 2 sulfur cluster binding
HEQ83_RS04775	COG0668	transmembrane transport
HEQ83_RS04780	COG2719	SpoVR family
HEQ83_RS04785	COG1785	Belongs to the alkaline phosphatase family
HEQ83_RS04790	COG1388	LysM domain
HEQ83_RS04790	COG0791	NLP P60 protein
HEQ83_RS04795	COG0583	DNA-binding transcription factor activity
HEQ83_RS04800	COG0372	Belongs to the citrate synthase family
HEQ83_RS04805	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS04810	COG0531	amino acid
HEQ83_RS04815	COG0733	neurotransmitter:sodium symporter activity
HEQ83_RS04830	COG1595	DNA-templated transcription, initiation
HEQ83_RS04835	COG0204	Acyl-transferase
HEQ83_RS04840	COG1253	flavin adenine dinucleotide binding
HEQ83_RS04845	COG0789	Transcriptional regulator
HEQ83_RS04850	COG0436	Aminotransferase
HEQ83_RS04855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HEQ83_RS04860	COG1253	flavin adenine dinucleotide binding
HEQ83_RS04865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEQ83_RS04870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEQ83_RS04875	COG0584	glycerophosphoryl diester phosphodiesterase
HEQ83_RS04885	COG0668	transmembrane transport
HEQ83_RS04890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HEQ83_RS04895	COG0726	polysaccharide deacetylase
HEQ83_RS04900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HEQ83_RS04905	COG3226	Transcriptional regulator
HEQ83_RS04915	COG0589	response to stress
HEQ83_RS04920	COG1132	(ABC) transporter
HEQ83_RS04925	COG1132	(ABC) transporter
HEQ83_RS04930	COG0702	epimerase
HEQ83_RS04945	COG0189	ligase activity
HEQ83_RS04950	COG0189	ligase activity
HEQ83_RS04965	COG4335	DNA alkylation repair
HEQ83_RS04970	COG0561	phosphatase activity
HEQ83_RS04975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HEQ83_RS04985	COG0475	glutathione-regulated potassium exporter activity
HEQ83_RS04990	COG0490	domain, Protein
HEQ83_RS05000	COG1024	Enoyl-CoA hydratase
HEQ83_RS05010	COG4152	abc transporter atp-binding protein
HEQ83_RS05015	COG1668	transmembrane transport
HEQ83_RS05020	COG0420	3'-5' exonuclease activity
HEQ83_RS05025	COG4717	serine-type aminopeptidase activity
HEQ83_RS05040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HEQ83_RS05075	COG4980	gas vesicle protein
HEQ83_RS05090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEQ83_RS05095	COG0537	adenosine 5'-monophosphoramidase activity
HEQ83_RS05100	COG1131	(ABC) transporter
HEQ83_RS05105	COG4473	ABC transporter
HEQ83_RS05115	COG1473	amidohydrolase
HEQ83_RS05120	COG3069	C4-dicarboxylate transmembrane transporter activity
HEQ83_RS05125	COG2329	Antibiotic biosynthesis monooxygenase
HEQ83_RS05130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HEQ83_RS05150	COG1309	transcriptional regulator
HEQ83_RS05155	COG1511	domain protein
HEQ83_RS05160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEQ83_RS05170	COG1363	Peptidase, m42
HEQ83_RS05175	COG1301	dicarboxylic acid transport
HEQ83_RS05185	COG1234	tRNA 3'-trailer cleavage
HEQ83_RS05190	COG0095	Lipoate-protein ligase
HEQ83_RS05195	COG0702	epimerase
HEQ83_RS05200	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS05210	COG0501	Belongs to the peptidase M48B family
HEQ83_RS05215	COG1404	Belongs to the peptidase S8 family
HEQ83_RS05225	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HEQ83_RS05230	COG0406	alpha-ribazole phosphatase activity
HEQ83_RS05235	COG0183	Belongs to the thiolase family
HEQ83_RS05240	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS05245	COG1268	BioY protein
HEQ83_RS05250	COG0840	transmembrane signaling receptor activity
HEQ83_RS05255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HEQ83_RS05255	COG0723	plastoquinol--plastocyanin reductase activity
HEQ83_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS05270	COG4903	ComK protein
HEQ83_RS05280	COG5646	InterPro IPR014922
HEQ83_RS05300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEQ83_RS05315	COG0398	Pfam SNARE associated Golgi protein
HEQ83_RS05320	COG0681	Belongs to the peptidase S26 family
HEQ83_RS05325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HEQ83_RS05330	COG1846	Transcriptional regulator
HEQ83_RS05335	COG3180	Ammonia monooxygenase
HEQ83_RS05340	COG2814	Major facilitator Superfamily
HEQ83_RS05350	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HEQ83_RS05355	COG2323	membrane
HEQ83_RS05370	COG0420	3'-5' exonuclease activity
HEQ83_RS05375	COG0419	ATPase involved in DNA repair
HEQ83_RS05380	COG1403	HNH endonuclease
HEQ83_RS05420	COG0179	Fumarylacetoacetate (FAA) hydrolase
HEQ83_RS05440	COG0367	asparagine synthase
HEQ83_RS05445	COG1562	ergosterol biosynthetic process
HEQ83_RS05450	COG0534	Mate efflux family protein
HEQ83_RS05455	COG1917	Cupin 2, conserved barrel domain protein
HEQ83_RS05455	COG2207	Transcriptional regulator
HEQ83_RS05460	COG1609	Transcriptional regulator
HEQ83_RS05465	COG0673	inositol 2-dehydrogenase activity
HEQ83_RS05470	COG2318	DinB family
HEQ83_RS05475	COG1357	PFAM Pentapeptide repeats (8 copies)
HEQ83_RS05480	COG2153	protein acetylation
HEQ83_RS05485	COG0646	methionine synthase
HEQ83_RS05485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HEQ83_RS05495	COG2996	Protein conserved in bacteria
HEQ83_RS05505	COG0840	transmembrane signaling receptor activity
HEQ83_RS05515	COG1307	EDD domain protein, DegV family
HEQ83_RS05520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEQ83_RS05540	COG0561	phosphatase activity
HEQ83_RS05545	COG1073	alpha beta
HEQ83_RS05550	COG2151	metal-sulfur cluster biosynthetic enzyme
HEQ83_RS05560	COG0277	FAD linked oxidase domain protein
HEQ83_RS05565	COG2271	Major facilitator Superfamily
HEQ83_RS05575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEQ83_RS05585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HEQ83_RS05590	COG0505	Belongs to the CarA family
HEQ83_RS05595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HEQ83_RS05600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEQ83_RS05615	COG2267	carboxylic ester hydrolase activity
HEQ83_RS05625	COG1744	ABC transporter substrate-binding protein PnrA-like
HEQ83_RS05640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEQ83_RS05645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HEQ83_RS05650	COG5504	Zn-dependent protease
HEQ83_RS05655	COG0444	Belongs to the ABC transporter superfamily
HEQ83_RS05660	COG4608	Belongs to the ABC transporter superfamily
HEQ83_RS05670	COG0601	transmembrane transport
HEQ83_RS05675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEQ83_RS05685	COG0180	Tryptophanyl-tRNA synthetase
HEQ83_RS05690	COG4166	transmembrane transport
HEQ83_RS05695	COG0601	transmembrane transport
HEQ83_RS05700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEQ83_RS05705	COG0444	Belongs to the ABC transporter superfamily
HEQ83_RS05710	COG4608	Belongs to the ABC transporter superfamily
HEQ83_RS05720	COG0456	acetyltransferase
HEQ83_RS05725	COG1393	Belongs to the ArsC family
HEQ83_RS05730	COG0861	Integral membrane protein TerC family
HEQ83_RS05735	COG4862	establishment of competence for transformation
HEQ83_RS05740	COG4469	Competence protein
HEQ83_RS05745	COG1164	Oligoendopeptidase f
HEQ83_RS05760	COG2346	COG2346, Truncated hemoglobins
HEQ83_RS05765	COG0741	lytic transglycosylase activity
HEQ83_RS05770	COG4116	CYTH
HEQ83_RS05780	COG2357	RelA SpoT domain protein
HEQ83_RS05785	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEQ83_RS05790	COG0564	pseudouridine synthase activity
HEQ83_RS05800	COG0569	domain protein
HEQ83_RS05800	COG0475	glutathione-regulated potassium exporter activity
HEQ83_RS05805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEQ83_RS05810	COG0352	thiamine-phosphate diphosphorylase activity
HEQ83_RS05815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HEQ83_RS05820	COG2104	thiamine diphosphate biosynthetic process
HEQ83_RS05830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HEQ83_RS05835	COG0351	phosphomethylpyrimidine kinase
HEQ83_RS05840	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HEQ83_RS05895	COG0210	DNA helicase
HEQ83_RS05915	COG1131	(ABC) transporter
HEQ83_RS05925	COG2153	protein acetylation
HEQ83_RS05935	COG2382	esterase
HEQ83_RS05940	COG0626	cystathionine gamma-synthase activity
HEQ83_RS05945	COG0626	cystathionine gamma-synthase activity
HEQ83_RS05960	COG5444	nuclease activity
HEQ83_RS05970	COG0346	lactoylglutathione lyase activity
HEQ83_RS05975	COG2367	Beta-lactamase
HEQ83_RS05980	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HEQ83_RS05985	COG0477	Major facilitator Superfamily
HEQ83_RS05990	COG1846	Transcriptional regulator
HEQ83_RS06000	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HEQ83_RS06005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEQ83_RS06010	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEQ83_RS06015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HEQ83_RS06015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HEQ83_RS06020	COG1447	Phosphotransferase system cellobiose-specific component IIA
HEQ83_RS06030	COG1349	DNA-binding transcription factor activity
HEQ83_RS06045	COG1285	pathogenesis
HEQ83_RS06060	COG2205	protein histidine kinase activity
HEQ83_RS06070	COG3383	formate dehydrogenase (NAD+) activity
HEQ83_RS06075	COG2427	Protein of unknown function (DUF1641)
HEQ83_RS06080	COG2124	cytochrome p450
HEQ83_RS06085	COG1819	glycosyl
HEQ83_RS06095	COG1587	Uroporphyrinogen-III synthase
HEQ83_RS06100	COG0390	transport system, permease component
HEQ83_RS06105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HEQ83_RS06110	COG0697	spore germination
HEQ83_RS06115	COG4297	protein containing double-stranded beta helix domain
HEQ83_RS06125	COG1252	NADH dehydrogenase
HEQ83_RS06135	COG2211	Major facilitator Superfamily
HEQ83_RS06140	COG1609	Transcriptional regulator
HEQ83_RS06145	COG0246	Mannitol dehydrogenase
HEQ83_RS06150	COG2721	sulfolactate sulfo-lyase activity
HEQ83_RS06155	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS06160	COG2205	protein histidine kinase activity
HEQ83_RS06160	COG2770	Histidine kinase
HEQ83_RS06180	COG4585	Histidine kinase
HEQ83_RS06185	COG2197	response regulator
HEQ83_RS06220	COG0730	response to heat
HEQ83_RS06225	COG2318	DinB family
HEQ83_RS06230	COG0457	Tetratricopeptide repeat
HEQ83_RS06240	COG3409	Peptidoglycan-binding domain 1 protein
HEQ83_RS06240	COG1388	LysM domain
HEQ83_RS06240	COG5632	N-Acetylmuramoyl-L-alanine amidase
HEQ83_RS06250	COG4195	phage-related replication protein
HEQ83_RS06260	COG2856	Zn peptidase
HEQ83_RS06265	COG1396	sequence-specific DNA binding
HEQ83_RS06275	COG1522	sequence-specific DNA binding
HEQ83_RS06280	COG1484	DNA-dependent DNA replication
HEQ83_RS06300	COG1595	DNA-templated transcription, initiation
HEQ83_RS06305	COG3728	DNA packaging
HEQ83_RS06305	COG5484	DNA packaging
HEQ83_RS06310	COG1783	phage Terminase large subunit
HEQ83_RS06315	COG5518	Phage portal protein
HEQ83_RS06320	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HEQ83_RS06325	COG4653	Phage capsid family
HEQ83_RS06375	COG5412	phage tail tape measure protein
HEQ83_RS06375	COG3953	SLT domain
HEQ83_RS06375	COG5412	phage tail tape measure protein
HEQ83_RS06375	COG5412	phage tail tape measure protein
HEQ83_RS06375	COG3953	SLT domain
HEQ83_RS06375	COG3953	SLT domain
HEQ83_RS06380	COG1652	LysM domain
HEQ83_RS06385	COG4193	domain, Protein
HEQ83_RS06395	COG3628	GPW Gp25 family protein
HEQ83_RS06400	COG3299	homolog of phage Mu protein gp47
HEQ83_RS06405	COG3778	Protein conserved in bacteria
HEQ83_RS06445	COG5632	N-Acetylmuramoyl-L-alanine amidase
HEQ83_RS06445	COG3409	Peptidoglycan-binding domain 1 protein
HEQ83_RS06460	COG0306	phosphate transporter
HEQ83_RS06465	COG1392	Phosphate transport regulator
HEQ83_RS06470	COG0531	amino acid
HEQ83_RS06475	COG0346	lactoylglutathione lyase activity
HEQ83_RS06480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEQ83_RS06485	COG0463	Glycosyl transferase, family 2
HEQ83_RS06495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEQ83_RS06500	COG0477	Major facilitator Superfamily
HEQ83_RS06505	COG2362	D-Aminopeptidase
HEQ83_RS06510	COG0601	transmembrane transport
HEQ83_RS06515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEQ83_RS06520	COG0444	Belongs to the ABC transporter superfamily
HEQ83_RS06525	COG4166	transmembrane transport
HEQ83_RS06530	COG1619	proteins homologs of microcin C7 resistance protein MccF
HEQ83_RS06535	COG4948	Mandelate Racemase Muconate Lactonizing
HEQ83_RS06540	COG0791	NLP P60 protein
HEQ83_RS06545	COG4608	Belongs to the ABC transporter superfamily
HEQ83_RS06550	COG2706	6-phosphogluconolactonase activity
HEQ83_RS06555	COG1834	amidinotransferase
HEQ83_RS06560	COG1607	acyl-coa hydrolase
HEQ83_RS06565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEQ83_RS06570	COG2076	Multidrug Resistance protein
HEQ83_RS06575	COG2076	Multidrug Resistance protein
HEQ83_RS06580	COG0788	formyltetrahydrofolate deformylase activity
HEQ83_RS06585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEQ83_RS06595	COG1764	response to oxidative stress
HEQ83_RS06600	COG1846	Transcriptional regulator
HEQ83_RS06605	COG1764	response to oxidative stress
HEQ83_RS06620	COG0463	Glycosyl transferase, family 2
HEQ83_RS06620	COG0457	Tetratricopeptide repeat
HEQ83_RS06630	COG2814	Major facilitator Superfamily
HEQ83_RS06635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HEQ83_RS06645	COG1404	Belongs to the peptidase S8 family
HEQ83_RS06650	COG1366	Belongs to the anti-sigma-factor antagonist family
HEQ83_RS06655	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEQ83_RS06660	COG1122	ATPase activity
HEQ83_RS06665	COG4721	ABC-type cobalt transport system, permease component
HEQ83_RS06670	COG1388	LysM domain
HEQ83_RS06670	COG3858	chitin binding
HEQ83_RS06685	COG2239	Acts as a magnesium transporter
HEQ83_RS06690	COG0789	Transcriptional regulator
HEQ83_RS06705	COG1846	Transcriptional regulator
HEQ83_RS06710	COG0726	polysaccharide deacetylase
HEQ83_RS06715	COG3285	dna ligase
HEQ83_RS06715	COG1793	dna ligase
HEQ83_RS06720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HEQ83_RS06725	COG0586	Pfam SNARE associated Golgi protein
HEQ83_RS06730	COG0861	Integral membrane protein TerC family
HEQ83_RS06735	COG1191	sigma factor activity
HEQ83_RS06760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HEQ83_RS06765	COG2323	membrane
HEQ83_RS06775	COG3594	Acyltransferase
HEQ83_RS06780	COG5002	protein histidine kinase activity
HEQ83_RS06785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEQ83_RS06800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HEQ83_RS06805	COG0436	Aminotransferase
HEQ83_RS06835	COG3852	Histidine kinase
HEQ83_RS06840	COG1846	Transcriptional regulator
HEQ83_RS06845	COG1360	Flagellar Motor Protein
HEQ83_RS06850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HEQ83_RS06855	COG0542	response to heat
HEQ83_RS06860	COG3949	Membrane
HEQ83_RS06875	COG0720	synthase
HEQ83_RS06880	COG0602	queuosine metabolic process
HEQ83_RS06890	COG1733	regulation of RNA biosynthetic process
HEQ83_RS06895	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS06915	COG4873	Protein conserved in bacteria
HEQ83_RS06925	COG3773	Cell wall hydrolase
HEQ83_RS06930	COG2244	polysaccharide biosynthetic process
HEQ83_RS06935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEQ83_RS06940	COG2217	Heavy metal translocating P-type atpase
HEQ83_RS06945	COG0006	proline dipeptidase activity
HEQ83_RS06950	COG1609	Transcriptional regulator
HEQ83_RS06955	COG3711	transcriptional antiterminator
HEQ83_RS06960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEQ83_RS06960	COG2190	(PTS) system
HEQ83_RS06960	COG1263	PTS System
HEQ83_RS06965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEQ83_RS06970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEQ83_RS06980	COG1533	DNA photolyase activity
HEQ83_RS06985	COG0840	transmembrane signaling receptor activity
HEQ83_RS06990	COG2084	Dehydrogenase
HEQ83_RS06995	COG2340	Cysteine-rich secretory protein family
HEQ83_RS07000	COG0768	penicillin binding
HEQ83_RS07005	COG4191	Histidine kinase
HEQ83_RS07010	COG0436	Aminotransferase
HEQ83_RS07020	COG0784	Response regulator, receiver
HEQ83_RS07020	COG0835	chemotaxis
HEQ83_RS07030	COG2814	Major facilitator Superfamily
HEQ83_RS07035	COG1376	ErfK ybiS ycfS ynhG family protein
HEQ83_RS07040	COG1408	metallophosphoesterase
HEQ83_RS07045	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS07055	COG2200	EAL domain
HEQ83_RS07060	COG4703	Protein of unknown function (DUF1797)
HEQ83_RS07065	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HEQ83_RS07075	COG0517	IMP dehydrogenase activity
HEQ83_RS07080	COG0583	DNA-binding transcription factor activity
HEQ83_RS07085	COG0716	FMN binding
HEQ83_RS07095	COG0716	FMN binding
HEQ83_RS07115	COG0668	transmembrane transport
HEQ83_RS07120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEQ83_RS07140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HEQ83_RS07145	COG0303	'Molybdopterin
HEQ83_RS07150	COG1763	Mo-molybdopterin cofactor biosynthetic process
HEQ83_RS07155	COG0314	molybdopterin synthase activity
HEQ83_RS07160	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEQ83_RS07170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEQ83_RS07175	COG1136	(ABC) transporter
HEQ83_RS07180	COG0577	efflux transmembrane transporter activity
HEQ83_RS07185	COG1349	DNA-binding transcription factor activity
HEQ83_RS07190	COG1105	Belongs to the carbohydrate kinase PfkB family
HEQ83_RS07195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEQ83_RS07195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEQ83_RS07195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEQ83_RS07200	COG0681	Belongs to the peptidase S26 family
HEQ83_RS07210	COG0488	(ABC) transporter
HEQ83_RS07215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEQ83_RS07220	COG2309	aminopeptidase activity
HEQ83_RS07230	COG1077	Cell shape determining protein MreB Mrl
HEQ83_RS07235	COG2002	toxin-antitoxin pair type II binding
HEQ83_RS07240	COG3852	Histidine kinase
HEQ83_RS07245	COG2105	PFAM AIG2 family protein
HEQ83_RS07245	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HEQ83_RS07250	COG0569	domain protein
HEQ83_RS07260	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEQ83_RS07270	COG0561	phosphatase activity
HEQ83_RS07275	COG0242	peptide deformylase activity
HEQ83_RS07285	COG0497	DNA recombination
HEQ83_RS07295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS07295	COG3321	synthase
HEQ83_RS07295	COG4221	oxidoreductase activity
HEQ83_RS07300	COG3321	synthase
HEQ83_RS07300	COG0300	oxidoreductase activity
HEQ83_RS07300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS07300	COG4221	oxidoreductase activity
HEQ83_RS07310	COG3321	synthase
HEQ83_RS07310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS07310	COG0300	oxidoreductase activity
HEQ83_RS07310	COG4221	oxidoreductase activity
HEQ83_RS07315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS07315	COG0300	oxidoreductase activity
HEQ83_RS07315	COG3321	synthase
HEQ83_RS07315	COG4221	oxidoreductase activity
HEQ83_RS07320	COG3321	synthase
HEQ83_RS07320	COG0300	oxidoreductase activity
HEQ83_RS07320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS07320	COG4221	oxidoreductase activity
HEQ83_RS07325	COG4221	oxidoreductase activity
HEQ83_RS07325	COG3321	synthase
HEQ83_RS07325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS07330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HEQ83_RS07335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HEQ83_RS07340	COG0022	dehydrogenase e1 component
HEQ83_RS07345	COG0508	dehydrogenase complex catalyzes the overall conversion of
HEQ83_RS07350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEQ83_RS07355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEQ83_RS07370	COG1982	Orn Lys Arg decarboxylase major
HEQ83_RS07390	COG0483	inositol monophosphate 1-phosphatase activity
HEQ83_RS07400	COG3227	Zinc metalloprotease (Elastase)
HEQ83_RS07415	COG1595	DNA-templated transcription, initiation
HEQ83_RS07445	COG4896	Protein conserved in bacteria
HEQ83_RS07455	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HEQ83_RS07460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEQ83_RS07465	COG2066	Belongs to the glutaminase family
HEQ83_RS07475	COG0772	Belongs to the SEDS family
HEQ83_RS07480	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEQ83_RS07495	COG2010	Cytochrome c
HEQ83_RS07495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HEQ83_RS07500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEQ83_RS07505	COG1845	cytochrome c oxidase, subunit III
HEQ83_RS07510	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HEQ83_RS07515	COG3336	cytochrome c oxidase
HEQ83_RS07525	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HEQ83_RS07530	COG2340	Cysteine-rich secretory protein family
HEQ83_RS07545	COG3679	Belongs to the UPF0342 family
HEQ83_RS07560	COG0742	ribosomal rna small subunit methyltransferase
HEQ83_RS07570	COG3314	Sporulation integral membrane protein YlbJ
HEQ83_RS07575	COG1752	Esterase of the alpha-beta hydrolase superfamily
HEQ83_RS07580	COG3480	Lon protease (S16) C-terminal proteolytic domain
HEQ83_RS07590	COG1399	metal-binding, possibly nucleic acid-binding protein
HEQ83_RS07610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEQ83_RS07630	COG4839	cell division protein FtsL
HEQ83_RS07640	COG0768	penicillin binding
HEQ83_RS07660	COG0772	Belongs to the SEDS family
HEQ83_RS07675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HEQ83_RS07680	COG0849	cell division
HEQ83_RS07685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEQ83_RS07690	COG1404	Belongs to the peptidase S8 family
HEQ83_RS07690	COG4412	M6 family metalloprotease domain protein
HEQ83_RS07700	COG1191	sigma factor activity
HEQ83_RS07705	COG1191	sigma factor activity
HEQ83_RS07710	COG1119	ATPase activity
HEQ83_RS07715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HEQ83_RS07720	COG1873	PFAM PRC-barrel domain
HEQ83_RS07730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEQ83_RS07740	COG0762	integral membrane protein
HEQ83_RS07745	COG2302	S4 RNA-binding domain
HEQ83_RS07750	COG3599	regulation of cell shape
HEQ83_RS07755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEQ83_RS07760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HEQ83_RS07770	COG0564	pseudouridine synthase activity
HEQ83_RS07780	COG2233	PERMEase
HEQ83_RS07790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HEQ83_RS07795	COG0505	Belongs to the CarA family
HEQ83_RS07800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HEQ83_RS07815	COG0284	orotidine-5'-phosphate decarboxylase activity
HEQ83_RS07820	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEQ83_RS07830	COG0306	phosphate transporter
HEQ83_RS07845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HEQ83_RS07850	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HEQ83_RS07855	COG1648	precorrin-2 dehydrogenase activity
HEQ83_RS07865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HEQ83_RS07870	COG1561	YicC-like family, N-terminal region
HEQ83_RS07880	COG0194	GDP metabolic process
HEQ83_RS07890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEQ83_RS07895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEQ83_RS07900	COG0242	peptide deformylase activity
HEQ83_RS07910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEQ83_RS07910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEQ83_RS07920	COG0631	protein serine/threonine phosphatase activity
HEQ83_RS07925	COG2815	serine threonine protein kinase
HEQ83_RS07925	COG0515	serine threonine protein kinase
HEQ83_RS07935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HEQ83_RS07940	COG1564	THIamine pyrophosphokinase
HEQ83_RS07955	COG1302	Protein conserved in bacteria
HEQ83_RS07960	COG1461	Dihydroxyacetone kinase
HEQ83_RS07965	COG1760	l-serine dehydratase
HEQ83_RS07970	COG1760	l-serine dehydratase
HEQ83_RS07975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEQ83_RS07990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HEQ83_RS07995	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS08010	COG1196	nuclear chromosome segregation
HEQ83_RS08015	COG0552	protein localization to endoplasmic reticulum
HEQ83_RS08030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEQ83_RS08040	COG1837	Belongs to the UPF0109 family
HEQ83_RS08065	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEQ83_RS08080	COG2257	FlhB HrpN YscU SpaS Family
HEQ83_RS08090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEQ83_RS08095	COG0758	DNA mediated transformation
HEQ83_RS08100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEQ83_RS08110	COG4974	Belongs to the 'phage' integrase family
HEQ83_RS08130	COG1815	bacterial-type flagellum-dependent cell motility
HEQ83_RS08135	COG1558	bacterial-type flagellum-dependent cell motility
HEQ83_RS08140	COG1677	Flagellar hook-basal body complex protein FliE
HEQ83_RS08145	COG1766	The M ring may be actively involved in energy transduction
HEQ83_RS08150	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEQ83_RS08155	COG1317	bacterial-type flagellum organization
HEQ83_RS08160	COG1157	protein secretion by the type III secretion system
HEQ83_RS08165	COG2882	bacterial-type flagellum organization
HEQ83_RS08170	COG3334	PFAM MgtE intracellular
HEQ83_RS08175	COG3144	bacterial-type flagellum assembly
HEQ83_RS08180	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HEQ83_RS08185	COG4786	Flagellar basal body rod
HEQ83_RS08190	COG1582	Flagellar protein (FlbD)
HEQ83_RS08195	COG1580	Controls the rotational direction of flagella during chemotaxis
HEQ83_RS08200	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEQ83_RS08205	COG1776	CheC inhibitor of MCP methylation
HEQ83_RS08205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEQ83_RS08210	COG2201	protein-glutamate methylesterase activity
HEQ83_RS08215	COG3190	flagellar
HEQ83_RS08220	COG1338	Plays a role in the flagellum-specific transport system
HEQ83_RS08225	COG1987	bacterial-type flagellum assembly
HEQ83_RS08230	COG1684	flagellar biosynthetic protein fliR
HEQ83_RS08235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEQ83_RS08240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEQ83_RS08245	COG1419	protein localization to endoplasmic reticulum
HEQ83_RS08250	COG0455	bacterial-type flagellum organization
HEQ83_RS08255	COG2201	protein-glutamate methylesterase activity
HEQ83_RS08260	COG2198	Histidine kinase
HEQ83_RS08260	COG0643	Histidine kinase
HEQ83_RS08265	COG0835	chemotaxis
HEQ83_RS08270	COG1776	CheC inhibitor of MCP methylation
HEQ83_RS08280	COG1191	sigma factor activity
HEQ83_RS08310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEQ83_RS08315	COG4589	Belongs to the CDS family
HEQ83_RS08325	COG0750	zinc metalloprotease
HEQ83_RS08335	COG2176	DNA-directed DNA polymerase activity
HEQ83_RS08345	COG0195	Participates in both transcription termination and antitermination
HEQ83_RS08350	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HEQ83_RS08355	COG1358	cellular component organization or biogenesis
HEQ83_RS08365	COG1550	Protein conserved in bacteria
HEQ83_RS08380	COG0196	riboflavin kinase activity
HEQ83_RS08395	COG0726	polysaccharide deacetylase
HEQ83_RS08400	COG0612	Peptidase, M16
HEQ83_RS08405	COG1873	PFAM PRC-barrel domain
HEQ83_RS08410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEQ83_RS08415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEQ83_RS08420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEQ83_RS08425	COG0527	aspartate kinase activity
HEQ83_RS08435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEQ83_RS08440	COG0740	serine-type endopeptidase activity
HEQ83_RS08450	COG1674	ftsk spoiiie
HEQ83_RS08450	COG4980	gas vesicle protein
HEQ83_RS08455	COG2188	Transcriptional regulator
HEQ83_RS08460	COG2814	Major facilitator Superfamily
HEQ83_RS08465	COG1846	Transcriptional regulator
HEQ83_RS08470	COG2409	Drug exporters of the RND superfamily
HEQ83_RS08470	COG1033	growth of symbiont in host cell
HEQ83_RS08475	COG0612	Peptidase, M16
HEQ83_RS08480	COG0612	Peptidase, M16
HEQ83_RS08485	COG0300	oxidoreductase activity
HEQ83_RS08500	COG1426	Protein conserved in bacteria
HEQ83_RS08505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEQ83_RS08520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HEQ83_RS08530	COG1692	metallophosphoesterase
HEQ83_RS08535	COG2359	stage V sporulation protein S
HEQ83_RS08555	COG4550	Control of competence regulator ComK, YlbF/YmcA
HEQ83_RS08600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS08605	COG3425	synthase
HEQ83_RS08610	COG1024	Enoyl-CoA hydratase
HEQ83_RS08615	COG1024	Enoyl-CoA hydratase
HEQ83_RS08620	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS08620	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS08620	COG3321	synthase
HEQ83_RS08620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS08620	COG0300	oxidoreductase activity
HEQ83_RS08625	COG4221	oxidoreductase activity
HEQ83_RS08625	COG3321	synthase
HEQ83_RS08625	COG0300	oxidoreductase activity
HEQ83_RS08625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS08630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEQ83_RS08630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS08630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS08630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEQ83_RS08630	COG3321	synthase
HEQ83_RS08630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS08630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS08630	COG3321	synthase
HEQ83_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS08635	COG4221	oxidoreductase activity
HEQ83_RS08635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS08635	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS08635	COG3321	synthase
HEQ83_RS08640	COG3321	synthase
HEQ83_RS08640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS08640	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HEQ83_RS08640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HEQ83_RS08645	COG2124	cytochrome p450
HEQ83_RS08650	COG3209	COG3209 Rhs family protein
HEQ83_RS08655	COG3619	membrane
HEQ83_RS08665	COG1404	Belongs to the peptidase S8 family
HEQ83_RS08675	COG4195	phage-related replication protein
HEQ83_RS08680	COG1764	response to oxidative stress
HEQ83_RS08690	COG2076	Multidrug Resistance protein
HEQ83_RS08730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEQ83_RS08735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEQ83_RS08740	COG4112	unkown
HEQ83_RS08745	COG0860	N-Acetylmuramoyl-L-alanine amidase
HEQ83_RS08755	COG0464	growth
HEQ83_RS08760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEQ83_RS08765	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HEQ83_RS08770	COG0789	Transcriptional regulator
HEQ83_RS08775	COG0174	glutamine synthetase
HEQ83_RS08785	COG2211	Major facilitator Superfamily
HEQ83_RS08790	COG3507	Belongs to the glycosyl hydrolase 43 family
HEQ83_RS08805	COG1070	Carbohydrate kinase
HEQ83_RS08810	COG0574	Belongs to the PEP-utilizing enzyme family
HEQ83_RS08810	COG3848	Pyruvate phosphate dikinase
HEQ83_RS08830	COG2378	regulation of single-species biofilm formation
HEQ83_RS08835	COG2318	DinB family
HEQ83_RS08840	COG1064	alcohol dehydrogenase
HEQ83_RS08860	COG0456	acetyltransferase
HEQ83_RS08880	COG3397	chitin binding
HEQ83_RS08900	COG5434	Belongs to the glycosyl hydrolase 28 family
HEQ83_RS08905	COG0756	dUTP diphosphatase activity
HEQ83_RS08910	COG4195	phage-related replication protein
HEQ83_RS08945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HEQ83_RS08955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEQ83_RS08975	COG0785	Cytochrome C biogenesis protein
HEQ83_RS08980	COG2201	protein-glutamate methylesterase activity
HEQ83_RS08985	COG4846	Membrane protein involved in cytochrome C biogenesis
HEQ83_RS08995	COG0071	Belongs to the small heat shock protein (HSP20) family
HEQ83_RS09010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEQ83_RS09015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEQ83_RS09035	COG0824	Thioesterase
HEQ83_RS09045	COG4841	protein insertion into membrane
HEQ83_RS09055	COG1832	CoA-binding protein
HEQ83_RS09060	COG0187	DNA topoisomerase II activity
HEQ83_RS09065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEQ83_RS09075	COG1115	amino acid carrier protein
HEQ83_RS09085	COG1063	alcohol dehydrogenase
HEQ83_RS09090	COG0800	Aldolase
HEQ83_RS09095	COG1312	Catalyzes the dehydration of D-mannonate
HEQ83_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS09105	COG1609	Transcriptional regulator
HEQ83_RS09110	COG2271	Major facilitator Superfamily
HEQ83_RS09145	COG2205	protein histidine kinase activity
HEQ83_RS09150	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS09160	COG3507	Belongs to the glycosyl hydrolase 43 family
HEQ83_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS09190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HEQ83_RS09195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEQ83_RS09200	COG2610	gluconate transmembrane transporter activity
HEQ83_RS09205	COG2124	cytochrome p450
HEQ83_RS09225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HEQ83_RS09235	COG2246	polysaccharide biosynthetic process
HEQ83_RS09240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HEQ83_RS09245	COG0586	Pfam SNARE associated Golgi protein
HEQ83_RS09250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HEQ83_RS09255	COG1024	Enoyl-CoA hydratase
HEQ83_RS09260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEQ83_RS09265	COG0511	ligase activity, forming carbon-carbon bonds
HEQ83_RS09270	COG0439	Biotin carboxylase
HEQ83_RS09275	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS09280	COG1960	acyl-CoA dehydrogenase activity
HEQ83_RS09285	COG1649	PFAM Uncharacterised BCR, COG1649
HEQ83_RS09295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS09295	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HEQ83_RS09300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS09305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS09310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS09315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS09320	COG2027	D-alanyl-D-alanine carboxypeptidase
HEQ83_RS09325	COG2017	converts alpha-aldose to the beta-anomer
HEQ83_RS09330	COG0534	Mate efflux family protein
HEQ83_RS09345	COG0582	viral genome integration into host DNA
HEQ83_RS09350	COG0166	Belongs to the GPI family
HEQ83_RS09355	COG0405	Gamma-glutamyltransferase
HEQ83_RS09360	COG2814	Major facilitator Superfamily
HEQ83_RS09365	COG0640	Transcriptional regulator
HEQ83_RS09380	COG0604	alcohol dehydrogenase
HEQ83_RS09385	COG0493	'glutamate synthase
HEQ83_RS09390	COG0067	glutamate synthase
HEQ83_RS09390	COG0070	glutamate synthase
HEQ83_RS09390	COG0069	glutamate synthase activity
HEQ83_RS09395	COG0583	DNA-binding transcription factor activity
HEQ83_RS09400	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEQ83_RS09415	COG0300	oxidoreductase activity
HEQ83_RS09420	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEQ83_RS09430	COG2814	Major facilitator Superfamily
HEQ83_RS09435	COG1070	Carbohydrate kinase
HEQ83_RS09440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HEQ83_RS09445	COG0243	molybdopterin cofactor binding
HEQ83_RS09465	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS09470	COG1733	regulation of RNA biosynthetic process
HEQ83_RS09475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEQ83_RS09485	COG1309	transcriptional regulator
HEQ83_RS09490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEQ83_RS09500	COG0640	Transcriptional regulator
HEQ83_RS09505	COG0741	lytic transglycosylase activity
HEQ83_RS09510	COG2322	membrane
HEQ83_RS09525	COG1619	proteins homologs of microcin C7 resistance protein MccF
HEQ83_RS09535	COG1388	LysM domain
HEQ83_RS09535	COG3584	3D domain protein
HEQ83_RS09540	COG0514	ATP-dependent DNA helicase (RecQ)
HEQ83_RS09550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEQ83_RS09555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HEQ83_RS09570	COG0071	Belongs to the small heat shock protein (HSP20) family
HEQ83_RS09600	COG1012	belongs to the aldehyde dehydrogenase family
HEQ83_RS09605	COG1657	PFAM Prenyltransferase squalene oxidase
HEQ83_RS09610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEQ83_RS09615	COG0733	neurotransmitter:sodium symporter activity
HEQ83_RS09620	COG0385	Bile acid
HEQ83_RS09625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEQ83_RS09630	COG0508	dehydrogenase complex catalyzes the overall conversion of
HEQ83_RS09640	COG4548	von Willebrand factor, type A
HEQ83_RS09645	COG0714	Associated with various cellular activities
HEQ83_RS09650	COG2032	superoxide dismutase activity
HEQ83_RS09655	COG1388	LysM domain
HEQ83_RS09655	COG0791	NLP P60 protein
HEQ83_RS09660	COG1819	glycosyl
HEQ83_RS09665	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEQ83_RS09670	COG0534	Mate efflux family protein
HEQ83_RS09675	COG1366	Belongs to the anti-sigma-factor antagonist family
HEQ83_RS09680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HEQ83_RS09685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HEQ83_RS09695	COG2962	Rard protein
HEQ83_RS09710	COG1942	4-Oxalocrotonate Tautomerase
HEQ83_RS09720	COG1733	regulation of RNA biosynthetic process
HEQ83_RS09725	COG0778	Nitroreductase
HEQ83_RS09730	COG0400	carboxylic ester hydrolase activity
HEQ83_RS09735	COG0346	lactoylglutathione lyase activity
HEQ83_RS09745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEQ83_RS09755	COG2723	6-phospho-beta-galactosidase activity
HEQ83_RS09760	COG2188	Transcriptional regulator
HEQ83_RS09765	COG0793	Belongs to the peptidase S41A family
HEQ83_RS09765	COG3409	Peptidoglycan-binding domain 1 protein
HEQ83_RS09770	COG2226	methyltransferase
HEQ83_RS09780	COG1876	peptidase activity
HEQ83_RS09800	COG0671	phosphoesterase, PA-phosphatase related
HEQ83_RS09835	COG1509	lysine 2,3-aminomutase activity
HEQ83_RS09840	COG0456	acetyltransferase
HEQ83_RS09845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HEQ83_RS09850	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HEQ83_RS09855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEQ83_RS09860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HEQ83_RS09865	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HEQ83_RS09875	COG0456	acetyltransferase
HEQ83_RS09880	COG0463	Glycosyl transferase, family 2
HEQ83_RS09895	COG4641	Protein conserved in bacteria
HEQ83_RS09905	COG1086	Polysaccharide biosynthesis protein
HEQ83_RS09950	COG1388	LysM domain
HEQ83_RS09955	COG0457	Tetratricopeptide repeat
HEQ83_RS09965	COG3391	amine dehydrogenase activity
HEQ83_RS10000	COG5444	nuclease activity
HEQ83_RS10005	COG4282	regulation of fungal-type cell wall biogenesis
HEQ83_RS10015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HEQ83_RS10035	COG1846	Transcriptional regulator
HEQ83_RS10040	COG4698	Protein conserved in bacteria
HEQ83_RS10045	COG2755	lipolytic protein G-D-S-L family
HEQ83_RS10050	COG1999	signal sequence binding
HEQ83_RS10060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEQ83_RS10065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HEQ83_RS10070	COG1272	protein, Hemolysin III
HEQ83_RS10075	COG0204	Acyl-transferase
HEQ83_RS10080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEQ83_RS10095	COG2136	Putative SAM-dependent methyltransferase
HEQ83_RS10095	COG2521	methyltransferase
HEQ83_RS10110	COG1413	lyase activity
HEQ83_RS10115	COG1418	mRNA catabolic process
HEQ83_RS10120	COG0386	Belongs to the glutathione peroxidase family
HEQ83_RS10130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEQ83_RS10140	COG1278	Cold shock
HEQ83_RS10160	COG0328	RNA-DNA hybrid ribonuclease activity
HEQ83_RS10165	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEQ83_RS10170	COG0328	RNA-DNA hybrid ribonuclease activity
HEQ83_RS10180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEQ83_RS10195	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEQ83_RS10205	COG1755	Isoprenylcysteine carboxyl methyltransferase
HEQ83_RS10210	COG3424	synthase
HEQ83_RS10235	COG1335	isochorismatase
HEQ83_RS10245	COG2233	PERMEase
HEQ83_RS10255	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HEQ83_RS10260	COG1199	ATP-dependent helicase activity
HEQ83_RS10275	COG0116	Belongs to the methyltransferase superfamily
HEQ83_RS10305	COG3359	exonuclease
HEQ83_RS10310	COG1111	helicase
HEQ83_RS10310	COG1205	dead DEAH box helicase
HEQ83_RS10315	COG2190	(PTS) system
HEQ83_RS10320	COG0071	Belongs to the small heat shock protein (HSP20) family
HEQ83_RS10360	COG4499	WXG100 protein secretion system (Wss), protein YukC
HEQ83_RS10360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HEQ83_RS10370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEQ83_RS10375	COG3935	DnaD domain protein
HEQ83_RS10385	COG0436	Aminotransferase
HEQ83_RS10390	COG5353	protein conserved in bacteria
HEQ83_RS10400	COG1199	ATP-dependent helicase activity
HEQ83_RS10400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HEQ83_RS10430	COG0438	transferase activity, transferring glycosyl groups
HEQ83_RS10435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HEQ83_RS10450	COG1694	Mazg nucleotide pyrophosphohydrolase
HEQ83_RS10455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEQ83_RS10460	COG2140	Oxalate decarboxylase
HEQ83_RS10470	COG4347	Protein of unknown function (DUF1405)
HEQ83_RS10475	COG2010	Cytochrome c
HEQ83_RS10475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HEQ83_RS10480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HEQ83_RS10485	COG0723	plastoquinol--plastocyanin reductase activity
HEQ83_RS10500	COG0457	Tetratricopeptide repeat
HEQ83_RS10510	COG0287	Prephenate dehydrogenase
HEQ83_RS10545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEQ83_RS10550	COG4401	Chorismate mutase type I
HEQ83_RS10565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HEQ83_RS10570	COG0105	UTP biosynthetic process
HEQ83_RS10575	COG0142	geranyltranstransferase activity
HEQ83_RS10585	COG0142	geranyltranstransferase activity
HEQ83_RS10600	COG0776	regulation of translation
HEQ83_RS10605	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEQ83_RS10645	COG0539	negative regulation of cytoplasmic translation
HEQ83_RS10660	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HEQ83_RS10665	COG2959	enzyme of heme biosynthesis
HEQ83_RS10670	COG3409	Peptidoglycan-binding domain 1 protein
HEQ83_RS10670	COG3773	Cell wall hydrolase
HEQ83_RS10675	COG2339	peptidase activity
HEQ83_RS10680	COG0492	ferredoxin-NADP+ reductase activity
HEQ83_RS10685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HEQ83_RS10690	COG4862	establishment of competence for transformation
HEQ83_RS10695	COG1408	metallophosphoesterase
HEQ83_RS10705	COG1388	LysM domain
HEQ83_RS10710	COG1266	CAAX protease self-immunity
HEQ83_RS10715	COG0514	ATP-dependent DNA helicase (RecQ)
HEQ83_RS10720	COG4955	Helix-turn-helix domain
HEQ83_RS10725	COG1141	Ferredoxin
HEQ83_RS10730	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEQ83_RS10735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HEQ83_RS10745	COG1595	DNA-templated transcription, initiation
HEQ83_RS10750	COG5002	protein histidine kinase activity
HEQ83_RS10755	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS10760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HEQ83_RS10765	COG1333	cytochrome c biogenesis protein
HEQ83_RS10770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEQ83_RS10775	COG1187	pseudouridine synthase activity
HEQ83_RS10780	COG0700	Nucleoside recognition
HEQ83_RS10785	COG2715	membrane protein required for spore maturation
HEQ83_RS10790	COG1686	Belongs to the peptidase S11 family
HEQ83_RS10815	COG1547	Domain of unknown function (DUF309)
HEQ83_RS10820	COG0456	acetyltransferase
HEQ83_RS10835	COG0307	riboflavin synthase, alpha
HEQ83_RS10840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEQ83_RS10840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEQ83_RS10850	COG0681	Belongs to the peptidase S26 family
HEQ83_RS10860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEQ83_RS10865	COG4086	secreted protein
HEQ83_RS10870	COG0019	diaminopimelate decarboxylase activity
HEQ83_RS10875	COG0697	spore germination
HEQ83_RS10890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEQ83_RS10910	COG1191	sigma factor activity
HEQ83_RS10920	COG1366	Belongs to the anti-sigma-factor antagonist family
HEQ83_RS10925	COG1686	Belongs to the peptidase S11 family
HEQ83_RS10930	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEQ83_RS10935	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEQ83_RS10940	COG4974	Belongs to the 'phage' integrase family
HEQ83_RS10950	COG0735	belongs to the Fur family
HEQ83_RS10955	COG1300	Membrane
HEQ83_RS10970	COG0281	malic enzyme
HEQ83_RS10975	COG1757	Na H antiporter
HEQ83_RS10980	COG1027	Aspartate ammonia-lyase
HEQ83_RS10985	COG0252	asparaginase activity
HEQ83_RS10990	COG1396	sequence-specific DNA binding
HEQ83_RS10995	COG1379	DNA repair
HEQ83_RS11000	COG0494	nUDIX hydrolase
HEQ83_RS11010	COG0667	Aldo Keto reductase
HEQ83_RS11020	COG1073	alpha beta
HEQ83_RS11030	COG4918	Iron-sulphur cluster biosynthesis
HEQ83_RS11035	COG0456	acetyltransferase
HEQ83_RS11035	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEQ83_RS11040	COG2329	Antibiotic biosynthesis monooxygenase
HEQ83_RS11045	COG0456	acetyltransferase
HEQ83_RS11050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEQ83_RS11065	COG0628	permease
HEQ83_RS11075	COG0346	lactoylglutathione lyase activity
HEQ83_RS11085	COG3048	D-serine ammonia-lyase activity
HEQ83_RS11090	COG0300	oxidoreductase activity
HEQ83_RS11095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEQ83_RS11100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEQ83_RS11105	COG1024	Enoyl-CoA hydratase
HEQ83_RS11110	COG3425	synthase
HEQ83_RS11115	COG2124	cytochrome p450
HEQ83_RS11120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS11120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEQ83_RS11120	COG3321	synthase
HEQ83_RS11120	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS11120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS11125	COG3321	synthase
HEQ83_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS11125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS11125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS11125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEQ83_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS11130	COG3321	synthase
HEQ83_RS11130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS11130	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS11130	COG0300	oxidoreductase activity
HEQ83_RS11135	COG0300	oxidoreductase activity
HEQ83_RS11135	COG3321	synthase
HEQ83_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS11135	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS11135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS11140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS11140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEQ83_RS11140	COG3321	synthase
HEQ83_RS11140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS11145	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS11145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS11145	COG3321	synthase
HEQ83_RS11145	COG0300	oxidoreductase activity
HEQ83_RS11145	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS11150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEQ83_RS11150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEQ83_RS11150	COG3321	synthase
HEQ83_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS11150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS11160	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS11175	COG2070	2-Nitropropane dioxygenase
HEQ83_RS11175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HEQ83_RS11180	COG0250	Participates in transcription elongation, termination and antitermination
HEQ83_RS11205	COG0596	Alpha beta hydrolase
HEQ83_RS11220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEQ83_RS11225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEQ83_RS11240	COG0706	membrane insertase activity
HEQ83_RS11245	COG2195	Cleaves the N-terminal amino acid of tripeptides
HEQ83_RS11250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HEQ83_RS11255	COG0346	lactoylglutathione lyase activity
HEQ83_RS11265	COG1376	ErfK ybiS ycfS ynhG family protein
HEQ83_RS11270	COG4129	membrane
HEQ83_RS11275	COG1126	abc transporter atp-binding protein
HEQ83_RS11280	COG0765	amino acid transport
HEQ83_RS11285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEQ83_RS11295	COG1597	lipid kinase activity
HEQ83_RS11300	COG0508	dehydrogenase complex catalyzes the overall conversion of
HEQ83_RS11305	COG0022	dehydrogenase e1 component
HEQ83_RS11310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HEQ83_RS11315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEQ83_RS11320	COG3426	butyrate kinase activity
HEQ83_RS11325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HEQ83_RS11330	COG0280	phosphate acetyltransferase
HEQ83_RS11335	COG3829	transcription factor binding
HEQ83_RS11335	COG3290	protein histidine kinase activity
HEQ83_RS11345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HEQ83_RS11350	COG2079	MmgE PrpD family protein
HEQ83_RS11355	COG0372	Belongs to the citrate synthase family
HEQ83_RS11360	COG1960	acyl-CoA dehydrogenase activity
HEQ83_RS11365	COG1250	3-hydroxyacyl-CoA dehydrogenase
HEQ83_RS11370	COG0183	Belongs to the thiolase family
HEQ83_RS11375	COG0584	glycerophosphoryl diester phosphodiesterase
HEQ83_RS11380	COG0860	N-Acetylmuramoyl-L-alanine amidase
HEQ83_RS11405	COG1902	pentaerythritol trinitrate reductase activity
HEQ83_RS11420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEQ83_RS11425	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS11430	COG0750	zinc metalloprotease
HEQ83_RS11435	COG0497	DNA recombination
HEQ83_RS11445	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HEQ83_RS11455	COG0142	geranyltranstransferase activity
HEQ83_RS11465	COG1570	exodeoxyribonuclease VII activity
HEQ83_RS11480	COG1302	Protein conserved in bacteria
HEQ83_RS11485	COG0439	Biotin carboxylase
HEQ83_RS11490	COG0511	ligase activity, forming carbon-carbon bonds
HEQ83_RS11530	COG3854	ATPases associated with a variety of cellular activities
HEQ83_RS11545	COG0006	proline dipeptidase activity
HEQ83_RS11555	COG3872	metal-dependent enzyme
HEQ83_RS11565	COG1752	Esterase of the alpha-beta hydrolase superfamily
HEQ83_RS11580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEQ83_RS11600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HEQ83_RS11615	COG1396	sequence-specific DNA binding
HEQ83_RS11625	COG0681	Belongs to the peptidase S26 family
HEQ83_RS11650	COG4940	Competence protein ComGF
HEQ83_RS11660	COG4970	Tfp pilus assembly protein FimT
HEQ83_RS11665	COG4537	Required for transformation and DNA binding
HEQ83_RS11670	COG1459	type II secretion system
HEQ83_RS11675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEQ83_RS11680	COG0598	Magnesium transport protein CorA
HEQ83_RS11685	COG1253	flavin adenine dinucleotide binding
HEQ83_RS11690	COG1366	Belongs to the anti-sigma-factor antagonist family
HEQ83_RS11700	COG1393	Belongs to the ArsC family
HEQ83_RS11710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEQ83_RS11720	COG0011	TIGRFAM Protein of
HEQ83_RS11730	COG2866	Carboxypeptidase
HEQ83_RS11735	COG1940	carbohydrate kinase activity
HEQ83_RS11740	COG4483	Protein conserved in bacteria
HEQ83_RS11745	COG1757	Na H antiporter
HEQ83_RS11755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEQ83_RS11770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEQ83_RS11775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HEQ83_RS11780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HEQ83_RS11785	COG0581	inorganic phosphate transmembrane transporter activity
HEQ83_RS11790	COG0573	inorganic phosphate transmembrane transporter activity
HEQ83_RS11795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HEQ83_RS11805	COG0477	Major facilitator Superfamily
HEQ83_RS11810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEQ83_RS11815	COG2839	Protein conserved in bacteria
HEQ83_RS11820	COG5521	maltodextrose utilization protein MalA
HEQ83_RS11825	COG1388	LysM domain
HEQ83_RS11835	COG4709	membrane
HEQ83_RS11840	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
HEQ83_RS11845	COG0735	belongs to the Fur family
HEQ83_RS11850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEQ83_RS11865	COG0513	Belongs to the DEAD box helicase family
HEQ83_RS11880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEQ83_RS11885	COG2384	SAM-dependent methyltransferase
HEQ83_RS11890	COG2010	Cytochrome c
HEQ83_RS11895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEQ83_RS11900	COG0358	DNA primase activity
HEQ83_RS11915	COG0517	IMP dehydrogenase activity
HEQ83_RS11920	COG0751	glycine-tRNA ligase activity
HEQ83_RS11940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEQ83_RS11945	COG0295	cytidine deaminase activity
HEQ83_RS11950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HEQ83_RS11960	COG1480	7TM receptor with intracellular HD hydrolase
HEQ83_RS11965	COG1702	phosphate starvation-inducible protein PhoH
HEQ83_RS11970	COG0561	phosphatase activity
HEQ83_RS11985	COG4864	UPF0365 protein
HEQ83_RS11990	COG1030	water channel activity
HEQ83_RS11995	COG1610	YqeY-like protein
HEQ83_RS12005	COG1283	sodium-dependent phosphate transmembrane transporter activity
HEQ83_RS12010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEQ83_RS12015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HEQ83_RS12045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HEQ83_RS12060	COG0860	N-Acetylmuramoyl-L-alanine amidase
HEQ83_RS12075	COG1466	dna polymerase III delta subunit
HEQ83_RS12090	COG2333	competence protein COMEC
HEQ83_RS12090	COG0658	competence protein
HEQ83_RS12095	COG2131	deaminase
HEQ83_RS12100	COG1555	photosystem II stabilization
HEQ83_RS12100	COG1596	polysaccharide export
HEQ83_RS12105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEQ83_RS12110	COG2226	methyltransferase
HEQ83_RS12115	COG0799	negative regulation of ribosome biogenesis
HEQ83_RS12120	COG1713	HD superfamily hydrolase involved in NAD metabolism
HEQ83_RS12130	COG1534	Rna-binding protein
HEQ83_RS12135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEQ83_RS12140	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEQ83_RS12145	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HEQ83_RS12155	COG2755	lipolytic protein G-D-S-L family
HEQ83_RS12165	COG0398	Pfam SNARE associated Golgi protein
HEQ83_RS12190	COG2207	Transcriptional regulator
HEQ83_RS12190	COG3708	Transcriptional regulator
HEQ83_RS12195	COG0563	adenylate kinase activity
HEQ83_RS12205	COG2814	Major facilitator Superfamily
HEQ83_RS12215	COG0456	acetyltransferase
HEQ83_RS12220	COG2318	DinB family
HEQ83_RS12230	COG0561	phosphatase activity
HEQ83_RS12235	COG0561	phosphatase activity
HEQ83_RS12245	COG1482	cell wall glycoprotein biosynthetic process
HEQ83_RS12250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEQ83_RS12250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEQ83_RS12250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEQ83_RS12255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEQ83_RS12255	COG3711	transcriptional antiterminator
HEQ83_RS12265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEQ83_RS12270	COG0583	DNA-binding transcription factor activity
HEQ83_RS12275	COG2814	Major facilitator Superfamily
HEQ83_RS12280	COG2124	cytochrome p450
HEQ83_RS12280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEQ83_RS12285	COG1309	transcriptional regulator
HEQ83_RS12290	COG2226	methyltransferase
HEQ83_RS12305	COG2116	formate transmembrane transporter activity
HEQ83_RS12310	COG5609	conserved protein (DUF2294)
HEQ83_RS12315	COG3383	formate dehydrogenase (NAD+) activity
HEQ83_RS12320	COG2427	Protein of unknown function (DUF1641)
HEQ83_RS12330	COG0626	cystathionine gamma-synthase activity
HEQ83_RS12335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HEQ83_RS12360	COG0768	penicillin binding
HEQ83_RS12385	COG4122	O-methyltransferase activity
HEQ83_RS12390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEQ83_RS12405	COG4472	Bacterial protein of unknown function (DUF965)
HEQ83_RS12415	COG0628	permease
HEQ83_RS12420	COG1126	abc transporter atp-binding protein
HEQ83_RS12425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEQ83_RS12430	COG0765	amino acid transport
HEQ83_RS12435	COG0765	amino acid transport
HEQ83_RS12450	COG3881	PFAM PRC-barrel domain
HEQ83_RS12455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HEQ83_RS12460	COG0457	Tetratricopeptide repeat
HEQ83_RS12470	COG1104	cysteine desulfurase activity
HEQ83_RS12475	COG1959	2 iron, 2 sulfur cluster binding
HEQ83_RS12480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HEQ83_RS12485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HEQ83_RS12510	COG3103	Sh3 type 3 domain protein
HEQ83_RS12510	COG0860	N-Acetylmuramoyl-L-alanine amidase
HEQ83_RS12510	COG4991	sh3 domain protein
HEQ83_RS12520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEQ83_RS12530	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HEQ83_RS12530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HEQ83_RS12535	COG5416	Lipopolysaccharide assembly protein A domain
HEQ83_RS12540	COG0490	domain, Protein
HEQ83_RS12545	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEQ83_RS12545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEQ83_RS12555	COG2244	polysaccharide biosynthetic process
HEQ83_RS12560	COG2323	membrane
HEQ83_RS12570	COG1862	Preprotein translocase
HEQ83_RS12615	COG1388	LysM domain
HEQ83_RS12625	COG0157	Belongs to the NadC ModD family
HEQ83_RS12630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HEQ83_RS12635	COG1104	cysteine desulfurase activity
HEQ83_RS12640	COG1827	regulation of RNA biosynthetic process
HEQ83_RS12645	COG0077	Prephenate dehydratase
HEQ83_RS12660	COG3290	protein histidine kinase activity
HEQ83_RS12665	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HEQ83_RS12670	COG2868	ribosomal protein
HEQ83_RS12680	COG1994	Peptidase M50
HEQ83_RS12685	COG0739	heme binding
HEQ83_RS12690	COG2894	cell division
HEQ83_RS12700	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HEQ83_RS12710	COG1077	Cell shape determining protein MreB Mrl
HEQ83_RS12730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HEQ83_RS12735	COG0285	dihydrofolate synthase activity
HEQ83_RS12740	COG0525	valine-tRNA ligase activity
HEQ83_RS12750	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEQ83_RS12755	COG1388	LysM domain
HEQ83_RS12765	COG0113	porphobilinogen synthase activity
HEQ83_RS12770	COG1587	Uroporphyrinogen-III synthase
HEQ83_RS12780	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HEQ83_RS12800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEQ83_RS12805	COG0470	DNA polymerase III
HEQ83_RS12805	COG1067	ATP-dependent peptidase activity
HEQ83_RS12820	COG0457	Tetratricopeptide repeat
HEQ83_RS12820	COG1477	protein flavinylation
HEQ83_RS12835	COG0473	3-isopropylmalate dehydrogenase activity
HEQ83_RS12850	COG0440	acetolactate synthase activity
HEQ83_RS12855	COG0028	Belongs to the TPP enzyme family
HEQ83_RS12885	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HEQ83_RS12905	COG0622	Phosphoesterase
HEQ83_RS12910	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEQ83_RS12920	COG5401	PFAM Sporulation and spore germination
HEQ83_RS12930	COG1846	Transcriptional regulator
HEQ83_RS12935	COG2197	response regulator
HEQ83_RS12940	COG0824	Thioesterase
HEQ83_RS12945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HEQ83_RS12950	COG1053	succinate dehydrogenase
HEQ83_RS12955	COG2009	succinate dehydrogenase
HEQ83_RS12960	COG1719	4-vinyl reductase, 4VR
HEQ83_RS12965	COG0527	aspartate kinase activity
HEQ83_RS12975	COG3118	belongs to the thioredoxin family
HEQ83_RS12980	COG3534	alpha-L-arabinofuranosidase
HEQ83_RS12985	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HEQ83_RS12990	COG2086	electron transfer activity
HEQ83_RS12995	COG1024	Enoyl-CoA hydratase
HEQ83_RS13000	COG1309	transcriptional regulator
HEQ83_RS13005	COG0318	PFAM AMP-dependent synthetase and ligase
HEQ83_RS13015	COG3766	membrane
HEQ83_RS13025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HEQ83_RS13025	COG1796	DNA polymerase
HEQ83_RS13030	COG1286	toxin biosynthetic process
HEQ83_RS13045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEQ83_RS13045	COG0072	phenylalanine-tRNA ligase activity
HEQ83_RS13050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEQ83_RS13055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEQ83_RS13065	COG3835	regulator
HEQ83_RS13070	COG0277	FAD linked oxidase domain protein
HEQ83_RS13075	COG0247	lactate metabolic process
HEQ83_RS13080	COG1966	Carbon starvation protein
HEQ83_RS13085	COG3534	alpha-L-arabinofuranosidase
HEQ83_RS13090	COG0395	ABC-type sugar transport system, permease component
HEQ83_RS13095	COG1175	transmembrane transport
HEQ83_RS13100	COG1653	transport
HEQ83_RS13110	COG0647	UMP catabolic process
HEQ83_RS13115	COG0235	Class ii aldolase
HEQ83_RS13120	COG1069	ribulokinase activity
HEQ83_RS13125	COG2160	L-arabinose isomerase activity
HEQ83_RS13130	COG3507	Belongs to the glycosyl hydrolase 43 family
HEQ83_RS13135	COG1363	Peptidase, m42
HEQ83_RS13145	COG3326	Membrane
HEQ83_RS13150	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEQ83_RS13160	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEQ83_RS13165	COG1346	cytolysis
HEQ83_RS13170	COG1380	Effector of murein hydrolase LrgA
HEQ83_RS13175	COG3279	Response regulator of the LytR AlgR family
HEQ83_RS13180	COG3275	phosphorelay sensor kinase activity
HEQ83_RS13185	COG1011	Hydrolase
HEQ83_RS13200	COG0398	Pfam SNARE associated Golgi protein
HEQ83_RS13205	COG1484	DNA-dependent DNA replication
HEQ83_RS13210	COG3611	Membrane attachment protein
HEQ83_RS13225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HEQ83_RS13230	COG1733	regulation of RNA biosynthetic process
HEQ83_RS13235	COG2814	Major facilitator Superfamily
HEQ83_RS13240	COG0656	L-ascorbic acid biosynthetic process
HEQ83_RS13245	COG0237	dephospho-CoA kinase activity
HEQ83_RS13250	COG1971	Probably functions as a manganese efflux pump
HEQ83_RS13255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HEQ83_RS13260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEQ83_RS13260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEQ83_RS13265	COG5002	protein histidine kinase activity
HEQ83_RS13270	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS13280	COG0538	isocitrate dehydrogenase activity
HEQ83_RS13285	COG0372	Belongs to the citrate synthase family
HEQ83_RS13305	COG0628	permease
HEQ83_RS13310	COG3030	protein affecting phage T7 exclusion by the F plasmid
HEQ83_RS13315	COG0469	pyruvate kinase activity
HEQ83_RS13335	COG0281	malic enzyme
HEQ83_RS13340	COG0587	DNA-directed DNA polymerase activity
HEQ83_RS13360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HEQ83_RS13370	COG4109	DRTGG domain
HEQ83_RS13380	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS13395	COG0521	Mo-molybdopterin cofactor biosynthetic process
HEQ83_RS13405	COG0827	DNA restriction-modification system
HEQ83_RS13410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEQ83_RS13415	COG3874	Sporulation protein YtfJ
HEQ83_RS13425	COG1714	RDD family
HEQ83_RS13430	COG0616	signal peptide processing
HEQ83_RS13435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEQ83_RS13440	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HEQ83_RS13445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HEQ83_RS13460	COG1104	cysteine desulfurase activity
HEQ83_RS13465	COG1114	Component of the transport system for branched-chain amino acids
HEQ83_RS13475	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HEQ83_RS13480	COG1309	transcriptional regulator
HEQ83_RS13485	COG1956	GAF domain-containing protein
HEQ83_RS13490	COG2199	diguanylate cyclase activity
HEQ83_RS13490	COG2203	Gaf domain
HEQ83_RS13505	COG1012	belongs to the aldehyde dehydrogenase family
HEQ83_RS13510	COG4282	regulation of fungal-type cell wall biogenesis
HEQ83_RS13545	COG1017	nitric oxide dioxygenase activity
HEQ83_RS13545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEQ83_RS13555	COG0693	protein deglycase activity
HEQ83_RS13570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEQ83_RS13575	COG1378	Sugar-specific transcriptional regulator TrmB
HEQ83_RS13595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HEQ83_RS13600	COG0454	-acetyltransferase
HEQ83_RS13605	COG0517	IMP dehydrogenase activity
HEQ83_RS13610	COG0123	including yeast histone deacetylase and acetoin utilization protein
HEQ83_RS13615	COG1360	Flagellar Motor Protein
HEQ83_RS13620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HEQ83_RS13625	COG1609	Transcriptional regulator
HEQ83_RS13630	COG1605	Chorismate mutase
HEQ83_RS13630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HEQ83_RS13635	COG3118	belongs to the thioredoxin family
HEQ83_RS13640	COG4980	gas vesicle protein
HEQ83_RS13645	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEQ83_RS13655	COG1674	ftsk spoiiie
HEQ83_RS13660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEQ83_RS13670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEQ83_RS13680	COG1363	Peptidase, m42
HEQ83_RS13685	COG5584	Small secreted protein
HEQ83_RS13690	COG0281	malic enzyme
HEQ83_RS13695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEQ83_RS13710	COG0510	thiamine kinase activity
HEQ83_RS13715	COG1597	lipid kinase activity
HEQ83_RS13725	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEQ83_RS13730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HEQ83_RS13735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HEQ83_RS13740	COG2252	PERMEase
HEQ83_RS13745	COG4473	ABC transporter
HEQ83_RS13750	COG1131	(ABC) transporter
HEQ83_RS13755	COG1349	DNA-binding transcription factor activity
HEQ83_RS13760	COG1187	pseudouridine synthase activity
HEQ83_RS13765	COG2244	polysaccharide biosynthetic process
HEQ83_RS13770	COG2081	HI0933 family
HEQ83_RS13775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HEQ83_RS13785	COG1609	Transcriptional regulator
HEQ83_RS13790	COG1653	transport
HEQ83_RS13795	COG1175	transmembrane transport
HEQ83_RS13800	COG0395	ABC-type sugar transport system, permease component
HEQ83_RS13805	COG1486	melibiose metabolic process
HEQ83_RS13815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEQ83_RS13830	COG2202	Pas domain
HEQ83_RS13830	COG1366	Belongs to the anti-sigma-factor antagonist family
HEQ83_RS13835	COG2814	Major facilitator Superfamily
HEQ83_RS13840	COG5522	Integral membrane protein (intg_mem_TP0381)
HEQ83_RS13845	COG0577	efflux transmembrane transporter activity
HEQ83_RS13850	COG1136	(ABC) transporter
HEQ83_RS13855	COG2205	protein histidine kinase activity
HEQ83_RS13860	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS13865	COG0577	efflux transmembrane transporter activity
HEQ83_RS13870	COG1136	(ABC) transporter
HEQ83_RS13890	COG1131	(ABC) transporter
HEQ83_RS13895	COG1725	Transcriptional regulator
HEQ83_RS13905	COG0640	Transcriptional regulator
HEQ83_RS13910	COG0477	Major facilitator Superfamily
HEQ83_RS13915	COG1242	4 iron, 4 sulfur cluster binding
HEQ83_RS13920	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HEQ83_RS13930	COG0584	glycerophosphoryl diester phosphodiesterase
HEQ83_RS13940	COG2267	carboxylic ester hydrolase activity
HEQ83_RS13945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEQ83_RS13950	COG1113	amino acid transport
HEQ83_RS13955	COG0367	asparagine synthase
HEQ83_RS13975	COG1506	peptidase
HEQ83_RS13980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HEQ83_RS13985	COG1116	anion transmembrane transporter activity
HEQ83_RS13990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HEQ83_RS13995	COG0494	nUDIX hydrolase
HEQ83_RS14000	COG4824	toxin secretion phage lysis holin
HEQ83_RS14005	COG0783	Belongs to the Dps family
HEQ83_RS14030	COG0288	reversible hydration of carbon dioxide
HEQ83_RS14040	COG1271	oxidase subunit
HEQ83_RS14045	COG1294	oxidase, subunit
HEQ83_RS14055	COG4948	Mandelate Racemase Muconate Lactonizing
HEQ83_RS14065	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEQ83_RS14070	COG0596	Alpha beta hydrolase
HEQ83_RS14080	COG1169	isochorismate synthase
HEQ83_RS14085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HEQ83_RS14090	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
HEQ83_RS14215	COG3859	Proton-coupled thiamine transporter YuaJ
HEQ83_RS14220	COG2268	Band 7 protein
HEQ83_RS14225	COG1585	Membrane protein implicated in regulation of membrane protease activity
HEQ83_RS14230	COG2318	DinB family
HEQ83_RS14240	COG1454	alcohol dehydrogenase
HEQ83_RS14245	COG1012	belongs to the aldehyde dehydrogenase family
HEQ83_RS14250	COG1510	regulation of RNA biosynthetic process
HEQ83_RS14260	COG0569	domain protein
HEQ83_RS14265	COG1705	Flagellar rod assembly protein muramidase FlgJ
HEQ83_RS14270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEQ83_RS14270	COG1017	nitric oxide dioxygenase activity
HEQ83_RS14295	COG0628	permease
HEQ83_RS14300	COG0673	inositol 2-dehydrogenase activity
HEQ83_RS14305	COG0693	protein deglycase activity
HEQ83_RS14310	COG0840	transmembrane signaling receptor activity
HEQ83_RS14315	COG0840	transmembrane signaling receptor activity
HEQ83_RS14320	COG0840	transmembrane signaling receptor activity
HEQ83_RS14325	COG0840	transmembrane signaling receptor activity
HEQ83_RS14340	COG2070	2-Nitropropane dioxygenase
HEQ83_RS14345	COG0432	Pfam Uncharacterised protein family UPF0047
HEQ83_RS14350	COG0366	Alpha amylase catalytic
HEQ83_RS14355	COG1253	flavin adenine dinucleotide binding
HEQ83_RS14360	COG2738	Putative neutral zinc metallopeptidase
HEQ83_RS14375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HEQ83_RS14400	COG1335	isochorismatase
HEQ83_RS14405	COG1979	alcohol dehydrogenase
HEQ83_RS14410	COG1979	alcohol dehydrogenase
HEQ83_RS14415	COG2155	Conserved Protein
HEQ83_RS14420	COG1098	S1 RNA binding domain
HEQ83_RS14425	COG0436	Aminotransferase
HEQ83_RS14430	COG1522	sequence-specific DNA binding
HEQ83_RS14435	COG2267	carboxylic ester hydrolase activity
HEQ83_RS14445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HEQ83_RS14450	COG2205	protein histidine kinase activity
HEQ83_RS14460	COG5018	Exonuclease
HEQ83_RS14465	COG2814	Major facilitator Superfamily
HEQ83_RS14470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HEQ83_RS14475	COG3011	Protein conserved in bacteria
HEQ83_RS14485	COG3290	protein histidine kinase activity
HEQ83_RS14490	COG4565	transcriptional regulatory protein
HEQ83_RS14520	COG2111	Na H antiporter
HEQ83_RS14520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HEQ83_RS14525	COG2111	Na H antiporter
HEQ83_RS14530	COG1006	Multisubunit Na H antiporter MnhC subunit
HEQ83_RS14535	COG0651	ATP synthesis coupled electron transport
HEQ83_RS14540	COG1863	multisubunit Na H antiporter MnhE subunit
HEQ83_RS14545	COG2212	antiporter activity
HEQ83_RS14550	COG1320	monovalent cation:proton antiporter activity
HEQ83_RS14555	COG2050	protein possibly involved in aromatic compounds catabolism
HEQ83_RS14560	COG2197	response regulator
HEQ83_RS14565	COG4585	Histidine kinase
HEQ83_RS14575	COG0142	geranyltranstransferase activity
HEQ83_RS14590	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HEQ83_RS14595	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEQ83_RS14600	COG1335	isochorismatase
HEQ83_RS14605	COG5506	Protein of unknown function (DUF1694)
HEQ83_RS14620	COG0628	permease
HEQ83_RS14630	COG1418	mRNA catabolic process
HEQ83_RS14635	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS14645	COG1511	domain protein
HEQ83_RS14650	COG0433	COG0433 Predicted ATPase
HEQ83_RS14650	COG1674	ftsk spoiiie
HEQ83_RS14655	COG4499	WXG100 protein secretion system (Wss), protein YukC
HEQ83_RS14660	COG5417	Belongs to the EsaB family
HEQ83_RS14665	COG4842	Belongs to the WXG100 family
HEQ83_RS14670	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEQ83_RS14670	COG2508	Transcriptional regulator
HEQ83_RS14675	COG0686	Belongs to the AlaDH PNT family
HEQ83_RS14680	COG5634	Uncharacterized conserved protein (DUF2278)
HEQ83_RS14685	COG3251	PFAM MbtH domain protein
HEQ83_RS14690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEQ83_RS14695	COG3433	isochorismatase activity
HEQ83_RS14695	COG1535	isochorismatase
HEQ83_RS14700	COG1021	2,3-dihydroxybenzoate-AMP ligase
HEQ83_RS14705	COG1169	isochorismate synthase
HEQ83_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS14715	COG2819	hydrolase of the alpha beta superfamily
HEQ83_RS14720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEQ83_RS14725	COG1268	BioY protein
HEQ83_RS14730	COG2056	Na+-H+ antiporter family
HEQ83_RS14740	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HEQ83_RS14745	COG3584	3D domain protein
HEQ83_RS14760	COG1252	NADH dehydrogenase
HEQ83_RS14790	COG1131	(ABC) transporter
HEQ83_RS14815	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEQ83_RS14820	COG0316	Belongs to the HesB IscA family
HEQ83_RS14830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEQ83_RS14840	COG1252	NADH dehydrogenase
HEQ83_RS14845	COG4837	Protein of unknown function (DUF1462)
HEQ83_RS14850	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HEQ83_RS14855	COG4946	Tricorn protease homolog
HEQ83_RS14855	COG1506	peptidase
HEQ83_RS14855	COG0823	Involved in the tonB-independent uptake of proteins
HEQ83_RS14865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEQ83_RS14870	COG0460	homoserine dehydrogenase
HEQ83_RS14875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEQ83_RS14880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HEQ83_RS14885	COG0647	UMP catabolic process
HEQ83_RS14890	COG2445	Protein of unknown function DUF86
HEQ83_RS14895	COG4470	Protein conserved in bacteria
HEQ83_RS14905	COG0739	heme binding
HEQ83_RS14915	COG0737	Belongs to the 5'-nucleotidase family
HEQ83_RS14920	COG0730	response to heat
HEQ83_RS14925	COG1801	Protein of unknown function DUF72
HEQ83_RS14940	COG2508	Transcriptional regulator
HEQ83_RS14955	COG2814	Major facilitator Superfamily
HEQ83_RS14960	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HEQ83_RS14965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HEQ83_RS14970	COG2356	endonuclease I
HEQ83_RS14975	COG3842	ATPase activity
HEQ83_RS14980	COG2188	Transcriptional regulator
HEQ83_RS14985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEQ83_RS14990	COG0395	ABC-type sugar transport system, permease component
HEQ83_RS14995	COG1175	transmembrane transport
HEQ83_RS15000	COG1653	transport
HEQ83_RS15005	COG2222	sugar isomerase
HEQ83_RS15015	COG0322	excinuclease ABC activity
HEQ83_RS15020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HEQ83_RS15025	COG2226	methyltransferase
HEQ83_RS15035	COG3409	Peptidoglycan-binding domain 1 protein
HEQ83_RS15040	COG0719	Fe-S assembly protein
HEQ83_RS15045	COG0822	iron-sulfur transferase activity
HEQ83_RS15050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEQ83_RS15055	COG0719	Fe-S assembly protein
HEQ83_RS15060	COG0396	ATPase activity
HEQ83_RS15070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEQ83_RS15075	COG1464	Belongs to the NlpA lipoprotein family
HEQ83_RS15080	COG2011	ABC-type metal ion transport system permease component
HEQ83_RS15085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEQ83_RS15095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEQ83_RS15100	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEQ83_RS15115	COG1393	Belongs to the ArsC family
HEQ83_RS15120	COG1960	acyl-CoA dehydrogenase activity
HEQ83_RS15125	COG0183	Belongs to the thiolase family
HEQ83_RS15130	COG1250	3-hydroxyacyl-CoA dehydrogenase
HEQ83_RS15130	COG1024	Enoyl-CoA hydratase
HEQ83_RS15150	COG5577	PFAM Coat F domain
HEQ83_RS15155	COG1846	Transcriptional regulator
HEQ83_RS15160	COG0477	Major facilitator Superfamily
HEQ83_RS15165	COG0583	DNA-binding transcription factor activity
HEQ83_RS15185	COG1120	ATPase activity
HEQ83_RS15200	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS15205	COG0783	Belongs to the Dps family
HEQ83_RS15210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEQ83_RS15215	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS15220	COG2770	Histidine kinase
HEQ83_RS15220	COG2205	protein histidine kinase activity
HEQ83_RS15230	COG1309	transcriptional regulator
HEQ83_RS15235	COG0114	fumarate hydratase activity
HEQ83_RS15245	COG0697	spore germination
HEQ83_RS15250	COG0814	amino acid
HEQ83_RS15260	COG2197	response regulator
HEQ83_RS15265	COG4585	Histidine kinase
HEQ83_RS15270	COG4758	membrane
HEQ83_RS15275	COG3595	metallopeptidase activity
HEQ83_RS15280	COG1842	Phage shock protein A
HEQ83_RS15285	COG4758	membrane
HEQ83_RS15290	COG2814	Major facilitator Superfamily
HEQ83_RS15295	COG2096	Adenosyltransferase
HEQ83_RS15300	COG1120	ATPase activity
HEQ83_RS15305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEQ83_RS15310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HEQ83_RS15315	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS15320	COG3386	PFAM SMP-30 Gluconolaconase
HEQ83_RS15325	COG2205	protein histidine kinase activity
HEQ83_RS15330	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS15340	COG1191	sigma factor activity
HEQ83_RS15350	COG2140	Oxalate decarboxylase
HEQ83_RS15360	COG1120	ATPase activity
HEQ83_RS15365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEQ83_RS15370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEQ83_RS15375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HEQ83_RS15380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HEQ83_RS15385	COG0531	amino acid
HEQ83_RS15395	COG1988	membrane-bound metal-dependent
HEQ83_RS15400	COG1368	sulfuric ester hydrolase activity
HEQ83_RS15405	COG1910	domain protein
HEQ83_RS15410	COG0725	ABC transporter, periplasmic molybdate-binding protein
HEQ83_RS15415	COG4149	molybdate abc transporter
HEQ83_RS15420	COG2197	response regulator
HEQ83_RS15425	COG3850	Histidine kinase
HEQ83_RS15430	COG1131	(ABC) transporter
HEQ83_RS15440	COG0842	Transport permease protein
HEQ83_RS15445	COG0656	L-ascorbic acid biosynthetic process
HEQ83_RS15465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEQ83_RS15470	COG3973	AAA domain
HEQ83_RS15475	COG2860	membrane
HEQ83_RS15485	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HEQ83_RS15490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HEQ83_RS15495	COG2217	Heavy metal translocating P-type atpase
HEQ83_RS15500	COG2217	Heavy metal translocating P-type atpase
HEQ83_RS15505	COG2608	mercury ion transmembrane transporter activity
HEQ83_RS15510	COG1937	Protein conserved in bacteria
HEQ83_RS15515	COG0673	inositol 2-dehydrogenase activity
HEQ83_RS15530	COG2814	Major facilitator Superfamily
HEQ83_RS15545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEQ83_RS15550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HEQ83_RS15555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEQ83_RS15560	COG1126	abc transporter atp-binding protein
HEQ83_RS15565	COG0765	amino acid transport
HEQ83_RS15570	COG0765	amino acid transport
HEQ83_RS15575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEQ83_RS15580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEQ83_RS15585	COG0454	-acetyltransferase
HEQ83_RS15590	COG0583	DNA-binding transcription factor activity
HEQ83_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS15600	COG2732	(Barnase) inhibitor
HEQ83_RS15615	COG0557	exoribonuclease II activity
HEQ83_RS15620	COG1647	Serine aminopeptidase, S33
HEQ83_RS15625	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HEQ83_RS15630	COG1476	TRANSCRIPTIONal
HEQ83_RS15635	COG1396	sequence-specific DNA binding
HEQ83_RS15640	COG1396	sequence-specific DNA binding
HEQ83_RS15645	COG1733	regulation of RNA biosynthetic process
HEQ83_RS15670	COG1131	(ABC) transporter
HEQ83_RS15675	COG1174	glycine betaine transport
HEQ83_RS15680	COG1732	Glycine betaine
HEQ83_RS15685	COG1174	glycine betaine transport
HEQ83_RS15690	COG1125	glycine betaine transport
HEQ83_RS15690	COG0517	IMP dehydrogenase activity
HEQ83_RS15695	COG1510	regulation of RNA biosynthetic process
HEQ83_RS15700	COG1174	glycine betaine transport
HEQ83_RS15705	COG1732	Glycine betaine
HEQ83_RS15710	COG1174	glycine betaine transport
HEQ83_RS15715	COG1125	glycine betaine transport
HEQ83_RS15715	COG0517	IMP dehydrogenase activity
HEQ83_RS15720	COG1510	regulation of RNA biosynthetic process
HEQ83_RS15725	COG2095	MarC family integral membrane protein
HEQ83_RS15730	COG3064	Membrane
HEQ83_RS15735	COG4640	response to antibiotic
HEQ83_RS15740	COG0456	acetyltransferase
HEQ83_RS15755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HEQ83_RS15770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEQ83_RS15775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEQ83_RS15780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEQ83_RS15790	COG2234	aminopeptidase activity
HEQ83_RS15810	COG0126	phosphoglycerate kinase activity
HEQ83_RS15815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HEQ83_RS15820	COG2390	Transcriptional regulator
HEQ83_RS15825	COG2814	Major facilitator Superfamily
HEQ83_RS15830	COG1609	Transcriptional regulator
HEQ83_RS15835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEQ83_RS15845	COG0583	DNA-binding transcription factor activity
HEQ83_RS15850	COG0697	spore germination
HEQ83_RS15855	COG1113	amino acid transport
HEQ83_RS15860	COG1737	Transcriptional regulator
HEQ83_RS15865	COG1070	Carbohydrate kinase
HEQ83_RS15890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEQ83_RS15895	COG2186	Transcriptional regulator
HEQ83_RS15900	COG1620	l-lactate permease
HEQ83_RS15905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HEQ83_RS15915	COG5039	Polysaccharide pyruvyl transferase
HEQ83_RS15920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEQ83_RS15925	COG0110	maltose O-acetyltransferase activity
HEQ83_RS15930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HEQ83_RS15935	COG2244	polysaccharide biosynthetic process
HEQ83_RS15940	COG1216	Glycosyl transferase, family 2
HEQ83_RS15945	COG5039	Polysaccharide pyruvyl transferase
HEQ83_RS15950	COG1216	Glycosyl transferase, family 2
HEQ83_RS15960	COG0438	transferase activity, transferring glycosyl groups
HEQ83_RS15965	COG1215	transferase activity, transferring glycosyl groups
HEQ83_RS15975	COG1086	Polysaccharide biosynthesis protein
HEQ83_RS15980	COG0489	protein tyrosine kinase activity
HEQ83_RS15985	COG3944	biosynthesis protein
HEQ83_RS15990	COG1396	sequence-specific DNA binding
HEQ83_RS15995	COG2272	Belongs to the type-B carboxylesterase lipase family
HEQ83_RS16005	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEQ83_RS16010	COG2364	Membrane
HEQ83_RS16015	COG0456	acetyltransferase
HEQ83_RS16020	COG3479	Phenolic acid decarboxylase
HEQ83_RS16055	COG2223	nitrite transmembrane transporter activity
HEQ83_RS16060	COG1609	Transcriptional regulator
HEQ83_RS16070	COG0583	DNA-binding transcription factor activity
HEQ83_RS16075	COG2828	Protein conserved in bacteria
HEQ83_RS16080	COG0477	Major facilitator Superfamily
HEQ83_RS16080	COG2814	Major facilitator Superfamily
HEQ83_RS16085	COG1611	Belongs to the LOG family
HEQ83_RS16090	COG1694	Mazg nucleotide pyrophosphohydrolase
HEQ83_RS16095	COG0659	secondary active sulfate transmembrane transporter activity
HEQ83_RS16100	COG0288	reversible hydration of carbon dioxide
HEQ83_RS16110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEQ83_RS16115	COG4290	ribonuclease
HEQ83_RS16120	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HEQ83_RS16125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEQ83_RS16135	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HEQ83_RS16145	COG1051	belongs to the nudix hydrolase family
HEQ83_RS16150	COG0492	ferredoxin-NADP+ reductase activity
HEQ83_RS16155	COG0791	NLP P60 protein
HEQ83_RS16155	COG3883	PFAM NLP P60 protein
HEQ83_RS16160	COG0457	Tetratricopeptide repeat
HEQ83_RS16165	COG5002	protein histidine kinase activity
HEQ83_RS16170	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS16180	COG1132	(ABC) transporter
HEQ83_RS16185	COG0140	phosphoribosyl-ATP diphosphatase activity
HEQ83_RS16185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HEQ83_RS16210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEQ83_RS16225	COG4990	cell redox homeostasis
HEQ83_RS16230	COG0110	maltose O-acetyltransferase activity
HEQ83_RS16250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEQ83_RS16260	COG2188	Transcriptional regulator
HEQ83_RS16265	COG1309	transcriptional regulator
HEQ83_RS16270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HEQ83_RS16275	COG1950	PFAM Membrane protein of
HEQ83_RS16280	COG1983	PspC domain protein
HEQ83_RS16285	COG3595	metallopeptidase activity
HEQ83_RS16300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HEQ83_RS16310	COG4897	Protein conserved in bacteria
HEQ83_RS16315	COG0574	Belongs to the PEP-utilizing enzyme family
HEQ83_RS16315	COG3848	Pyruvate phosphate dikinase
HEQ83_RS16320	COG1309	transcriptional regulator
HEQ83_RS16325	COG2814	Major facilitator Superfamily
HEQ83_RS16355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEQ83_RS16365	COG3409	Peptidoglycan-binding domain 1 protein
HEQ83_RS16365	COG0793	Belongs to the peptidase S41A family
HEQ83_RS16370	COG3420	alginic acid biosynthetic process
HEQ83_RS16375	COG2177	Part of the ABC transporter FtsEX involved in
HEQ83_RS16380	COG2884	Cell division ATP-binding protein ftsE
HEQ83_RS16385	COG2010	Cytochrome c
HEQ83_RS16390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEQ83_RS16405	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEQ83_RS16420	COG1516	flagellar protein fliS
HEQ83_RS16425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HEQ83_RS16430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEQ83_RS16450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEQ83_RS16455	COG1256	bacterial-type flagellum assembly
HEQ83_RS16455	COG4786	Flagellar basal body rod
HEQ83_RS16460	COG3418	PFAM FlgN family protein
HEQ83_RS16465	COG2747	anti-sigma28 factor FlgM
HEQ83_RS16475	COG1040	competence protein
HEQ83_RS16485	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEQ83_RS16490	COG1307	EDD domain protein, DegV family
HEQ83_RS16495	COG2197	response regulator
HEQ83_RS16500	COG4585	Histidine kinase
HEQ83_RS16505	COG1739	Uncharacterized protein family UPF0029
HEQ83_RS16510	COG1316	TRANSCRIPTIONal
HEQ83_RS16515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEQ83_RS16520	COG0438	transferase activity, transferring glycosyl groups
HEQ83_RS16525	COG1215	transferase activity, transferring glycosyl groups
HEQ83_RS16530	COG3206	protein involved in exopolysaccharide biosynthesis
HEQ83_RS16535	COG3307	-O-antigen
HEQ83_RS16540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEQ83_RS16545	COG0438	transferase activity, transferring glycosyl groups
HEQ83_RS16545	COG0297	glycogen (starch) synthase activity
HEQ83_RS16550	COG2244	polysaccharide biosynthetic process
HEQ83_RS16560	COG2247	cell wall binding repeat
HEQ83_RS16560	COG0860	N-Acetylmuramoyl-L-alanine amidase
HEQ83_RS16565	COG2385	sporulation resulting in formation of a cellular spore
HEQ83_RS16565	COG2247	cell wall binding repeat
HEQ83_RS16575	COG1316	TRANSCRIPTIONal
HEQ83_RS16580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HEQ83_RS16585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HEQ83_RS16590	COG1134	teichoic acid transport
HEQ83_RS16595	COG1682	transport, permease protein
HEQ83_RS16600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEQ83_RS16610	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HEQ83_RS16615	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HEQ83_RS16620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEQ83_RS16625	COG4193	domain, Protein
HEQ83_RS16630	COG1482	cell wall glycoprotein biosynthetic process
HEQ83_RS16635	COG0697	spore germination
HEQ83_RS16640	COG0814	amino acid
HEQ83_RS16650	COG1215	transferase activity, transferring glycosyl groups
HEQ83_RS16655	COG2814	Major facilitator Superfamily
HEQ83_RS16660	COG1316	TRANSCRIPTIONal
HEQ83_RS16665	COG0561	phosphatase activity
HEQ83_RS16670	COG2433	Pfam Transposase IS66
HEQ83_RS16675	COG0791	NLP P60 protein
HEQ83_RS16685	COG2843	Capsule synthesis protein
HEQ83_RS16695	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEQ83_RS16700	COG0697	spore germination
HEQ83_RS16705	COG0814	amino acid
HEQ83_RS16715	COG1609	Transcriptional regulator
HEQ83_RS16720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEQ83_RS16730	COG1129	ABC transporter
HEQ83_RS16735	COG1172	Belongs to the binding-protein-dependent transport system permease family
HEQ83_RS16740	COG1879	ABC-type sugar transport system periplasmic component
HEQ83_RS16745	COG3103	Sh3 type 3 domain protein
HEQ83_RS16750	COG2249	NAD(P)H dehydrogenase (quinone) activity
HEQ83_RS16755	COG3527	Alpha-acetolactate decarboxylase
HEQ83_RS16760	COG0028	Belongs to the TPP enzyme family
HEQ83_RS16765	COG0583	DNA-binding transcription factor activity
HEQ83_RS16770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEQ83_RS16785	COG5337	Spore coat protein CotH
HEQ83_RS16795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEQ83_RS16805	COG0405	Gamma-glutamyltransferase
HEQ83_RS16810	COG1522	sequence-specific DNA binding
HEQ83_RS16815	COG2059	Chromate
HEQ83_RS16820	COG2059	Chromate
HEQ83_RS16830	COG0655	NAD(P)H dehydrogenase (quinone) activity
HEQ83_RS16835	COG0583	DNA-binding transcription factor activity
HEQ83_RS16860	COG5444	nuclease activity
HEQ83_RS16885	COG5444	nuclease activity
HEQ83_RS16900	COG3878	Protein conserved in bacteria
HEQ83_RS16905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEQ83_RS16910	COG4464	protein tyrosine phosphatase activity
HEQ83_RS16915	COG0489	protein tyrosine kinase activity
HEQ83_RS16920	COG3944	biosynthesis protein
HEQ83_RS16930	COG4715	Zinc finger, swim domain protein
HEQ83_RS16935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HEQ83_RS16940	COG0561	phosphatase activity
HEQ83_RS16945	COG1349	DNA-binding transcription factor activity
HEQ83_RS16950	COG0629	single-stranded DNA binding
HEQ83_RS16975	COG0457	Tetratricopeptide repeat
HEQ83_RS16980	COG4786	Flagellar basal body rod
HEQ83_RS16985	COG4786	Flagellar basal body rod
HEQ83_RS16990	COG1077	Cell shape determining protein MreB Mrl
HEQ83_RS16995	COG1609	Transcriptional regulator
HEQ83_RS17000	COG1846	Transcriptional regulator
HEQ83_RS17005	COG2814	Major facilitator Superfamily
HEQ83_RS17010	COG1953	Uracil, thiamine, allantoin
HEQ83_RS17015	COG0477	Major facilitator Superfamily
HEQ83_RS17020	COG1335	isochorismatase
HEQ83_RS17025	COG0004	ammonium transporteR
HEQ83_RS17030	COG0347	Belongs to the P(II) protein family
HEQ83_RS17035	COG0772	Belongs to the SEDS family
HEQ83_RS17040	COG0671	phosphoesterase, PA-phosphatase related
HEQ83_RS17050	COG0739	heme binding
HEQ83_RS17055	COG1247	-acetyltransferase
HEQ83_RS17070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEQ83_RS17080	COG0726	polysaccharide deacetylase
HEQ83_RS17090	COG1959	2 iron, 2 sulfur cluster binding
HEQ83_RS17105	COG0831	urea catabolic process
HEQ83_RS17110	COG3237	CsbD-like
HEQ83_RS17115	COG1994	Peptidase M50
HEQ83_RS17120	COG0457	Tetratricopeptide repeat
HEQ83_RS17130	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HEQ83_RS17140	COG2304	oxidoreductase activity
HEQ83_RS17145	COG2304	oxidoreductase activity
HEQ83_RS17150	COG2385	sporulation resulting in formation of a cellular spore
HEQ83_RS17155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEQ83_RS17165	COG4836	Membrane
HEQ83_RS17235	COG0698	ribose 5-phosphate isomerase
HEQ83_RS17240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEQ83_RS17250	COG0009	L-threonylcarbamoyladenylate synthase
HEQ83_RS17255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HEQ83_RS17275	COG2890	protein-(glutamine-N5) methyltransferase activity
HEQ83_RS17280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEQ83_RS17285	COG0346	lactoylglutathione lyase activity
HEQ83_RS17290	COG0789	Transcriptional regulator
HEQ83_RS17295	COG0679	Auxin Efflux Carrier
HEQ83_RS17300	COG0281	malic enzyme
HEQ83_RS17315	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEQ83_RS17320	COG1494	fructose-1,6-bisphosphatase
HEQ83_RS17325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEQ83_RS17335	COG0191	fructose-bisphosphate aldolase activity
HEQ83_RS17340	COG2204	response regulator
HEQ83_RS17345	COG4821	SIS domain
HEQ83_RS17360	COG2181	nitrate reductase activity
HEQ83_RS17360	COG0247	lactate metabolic process
HEQ83_RS17365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEQ83_RS17380	COG1132	(ABC) transporter
HEQ83_RS17385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEQ83_RS17395	COG2181	nitrate reductase activity
HEQ83_RS17400	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HEQ83_RS17405	COG1140	nitrate reductase beta subunit
HEQ83_RS17410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEQ83_RS17415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HEQ83_RS17425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HEQ83_RS17430	COG2223	nitrite transmembrane transporter activity
HEQ83_RS17440	COG4506	Protein conserved in bacteria
HEQ83_RS17450	COG3391	amine dehydrogenase activity
HEQ83_RS17455	COG3391	amine dehydrogenase activity
HEQ83_RS17460	COG0457	Tetratricopeptide repeat
HEQ83_RS17505	COG0010	Belongs to the arginase family
HEQ83_RS17510	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEQ83_RS17515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HEQ83_RS17530	COG1994	Peptidase M50
HEQ83_RS17535	COG1942	4-Oxalocrotonate Tautomerase
HEQ83_RS17540	COG1846	Transcriptional regulator
HEQ83_RS17545	COG0531	amino acid
HEQ83_RS17550	COG3465	dGTPase activity
HEQ83_RS17555	COG1078	dGTPase activity
HEQ83_RS17570	COG1695	Transcriptional regulator
HEQ83_RS17580	COG1131	(ABC) transporter
HEQ83_RS17585	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HEQ83_RS17615	COG0583	DNA-binding transcription factor activity
HEQ83_RS17620	COG2855	membrane
HEQ83_RS17625	COG0280	phosphate acetyltransferase
HEQ83_RS17635	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS17640	COG0436	Aminotransferase
HEQ83_RS17670	COG2814	Major facilitator Superfamily
HEQ83_RS17675	COG2814	Major facilitator Superfamily
HEQ83_RS17680	COG0833	amino acid
HEQ83_RS17685	COG4187	Peptidase family M20/M25/M40
HEQ83_RS17690	COG1012	belongs to the aldehyde dehydrogenase family
HEQ83_RS17695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HEQ83_RS17705	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HEQ83_RS17710	COG1091	dTDP-4-dehydrorhamnose reductase activity
HEQ83_RS17715	COG1088	dTDP-glucose 4,6-dehydratase activity
HEQ83_RS17720	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEQ83_RS17725	COG3980	spore coat polysaccharide biosynthesis protein
HEQ83_RS17730	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HEQ83_RS17735	COG2089	acid synthase
HEQ83_RS17740	COG0456	acetyltransferase
HEQ83_RS17745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEQ83_RS17750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEQ83_RS17755	COG0463	Glycosyl transferase, family 2
HEQ83_RS17765	COG2363	Small membrane protein
HEQ83_RS17770	COG2233	PERMEase
HEQ83_RS17785	COG1216	Glycosyl transferase, family 2
HEQ83_RS17800	COG1695	Transcriptional regulator
HEQ83_RS17805	COG0351	phosphomethylpyrimidine kinase
HEQ83_RS17815	COG1621	beta-fructofuranosidase activity
HEQ83_RS17820	COG1263	PTS System
HEQ83_RS17820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEQ83_RS17825	COG3711	transcriptional antiterminator
HEQ83_RS17835	COG1404	Belongs to the peptidase S8 family
HEQ83_RS17840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEQ83_RS17845	COG0778	Nitroreductase
HEQ83_RS17850	COG0772	Belongs to the SEDS family
HEQ83_RS17855	COG0454	-acetyltransferase
HEQ83_RS17875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEQ83_RS17880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HEQ83_RS17885	COG2261	transglycosylase associated protein
HEQ83_RS17890	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HEQ83_RS17900	COG2246	polysaccharide biosynthetic process
HEQ83_RS17905	COG1309	transcriptional regulator
HEQ83_RS17925	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HEQ83_RS17930	COG2837	iron assimilation
HEQ83_RS17935	COG2822	iron ion transport
HEQ83_RS17950	COG0583	DNA-binding transcription factor activity
HEQ83_RS17960	COG1346	cytolysis
HEQ83_RS17965	COG4895	conserved protein (DUF2196)
HEQ83_RS17970	COG0789	Transcriptional regulator
HEQ83_RS17975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HEQ83_RS17980	COG0346	lactoylglutathione lyase activity
HEQ83_RS17985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HEQ83_RS17990	COG1404	Belongs to the peptidase S8 family
HEQ83_RS17995	COG1442	glycosyl transferase family 8
HEQ83_RS18000	COG2357	RelA SpoT domain protein
HEQ83_RS18005	COG1575	Belongs to the MenA family. Type 1 subfamily
HEQ83_RS18020	COG1696	Membrane protein involved in D-alanine export
HEQ83_RS18030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEQ83_RS18035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HEQ83_RS18040	COG1486	melibiose metabolic process
HEQ83_RS18045	COG1447	Phosphotransferase system cellobiose-specific component IIA
HEQ83_RS18050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HEQ83_RS18055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HEQ83_RS18060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEQ83_RS18060	COG3711	transcriptional antiterminator
HEQ83_RS18070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEQ83_RS18075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEQ83_RS18085	COG0640	Transcriptional regulator
HEQ83_RS18090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEQ83_RS18095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HEQ83_RS18100	COG1447	Phosphotransferase system cellobiose-specific component IIA
HEQ83_RS18105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HEQ83_RS18110	COG2723	6-phospho-beta-galactosidase activity
HEQ83_RS18115	COG1940	carbohydrate kinase activity
HEQ83_RS18120	COG1482	cell wall glycoprotein biosynthetic process
HEQ83_RS18130	COG0753	catalase activity
HEQ83_RS18135	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HEQ83_RS18140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HEQ83_RS18145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HEQ83_RS18150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEQ83_RS18155	COG4988	ABC transporter
HEQ83_RS18160	COG1294	oxidase, subunit
HEQ83_RS18165	COG1271	oxidase subunit
HEQ83_RS18170	COG3493	citrate carrier protein
HEQ83_RS18175	COG0726	polysaccharide deacetylase
HEQ83_RS18180	COG3842	ATPase activity
HEQ83_RS18185	COG2508	Transcriptional regulator
HEQ83_RS18190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEQ83_RS18200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEQ83_RS18215	COG4894	glucomannan catabolic process
HEQ83_RS18220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEQ83_RS18225	COG0500	methyltransferase
HEQ83_RS18230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEQ83_RS18250	COG0693	protein deglycase activity
HEQ83_RS18250	COG0753	catalase activity
HEQ83_RS18255	COG2851	Citrate transporter
HEQ83_RS18260	COG2273	Hydrolase Family 16
HEQ83_RS18270	COG2270	Major facilitator Superfamily
HEQ83_RS18275	COG0513	Belongs to the DEAD box helicase family
HEQ83_RS18345	COG0697	spore germination
HEQ83_RS18350	COG0589	response to stress
HEQ83_RS18360	COG0494	nUDIX hydrolase
HEQ83_RS18365	COG3507	Belongs to the glycosyl hydrolase 43 family
HEQ83_RS18390	COG0010	Belongs to the arginase family
HEQ83_RS18395	COG0833	amino acid
HEQ83_RS18400	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HEQ83_RS18405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEQ83_RS18415	COG2390	Transcriptional regulator
HEQ83_RS18420	COG0561	phosphatase activity
HEQ83_RS18450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HEQ83_RS18455	COG5294	Protein conserved in bacteria
HEQ83_RS18460	COG0577	efflux transmembrane transporter activity
HEQ83_RS18465	COG1136	(ABC) transporter
HEQ83_RS18470	COG2205	protein histidine kinase activity
HEQ83_RS18475	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS18490	COG1082	Xylose isomerase domain protein TIM barrel
HEQ83_RS18500	COG2814	Major facilitator Superfamily
HEQ83_RS18530	COG1349	DNA-binding transcription factor activity
HEQ83_RS18535	COG0667	Aldo Keto reductase
HEQ83_RS18540	COG2814	Major facilitator Superfamily
HEQ83_RS18555	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS18560	COG2197	response regulator
HEQ83_RS18565	COG4585	Histidine kinase
HEQ83_RS18570	COG3239	Fatty acid desaturase
HEQ83_RS18575	COG1309	transcriptional regulator
HEQ83_RS18580	COG1012	belongs to the aldehyde dehydrogenase family
HEQ83_RS18585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HEQ83_RS18595	COG0640	Transcriptional regulator
HEQ83_RS18600	COG2814	Major facilitator Superfamily
HEQ83_RS18605	COG1714	RDD family
HEQ83_RS18615	COG0450	alkyl hydroperoxide reductase
HEQ83_RS18620	COG3634	alkyl hydroperoxide reductase activity
HEQ83_RS18625	COG1113	amino acid transport
HEQ83_RS18635	COG2080	2 iron, 2 sulfur cluster binding
HEQ83_RS18650	COG2068	MobA-Related Protein
HEQ83_RS18655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HEQ83_RS18680	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HEQ83_RS18705	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEQ83_RS18710	COG0667	Aldo Keto reductase
HEQ83_RS18715	COG0456	acetyltransferase
HEQ83_RS18720	COG0457	Tetratricopeptide repeat
HEQ83_RS18725	COG0010	Belongs to the arginase family
HEQ83_RS18730	COG0833	amino acid
HEQ83_RS18735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HEQ83_RS18740	COG5658	integral membrane protein
HEQ83_RS18745	COG0640	Transcriptional regulator
HEQ83_RS18750	COG3829	transcription factor binding
HEQ83_RS18760	COG0488	(ABC) transporter
HEQ83_RS18775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HEQ83_RS18780	COG5002	protein histidine kinase activity
HEQ83_RS18790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEQ83_RS18795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HEQ83_RS18800	COG4853	Protein conserved in bacteria
HEQ83_RS18805	COG4863	YycH protein
HEQ83_RS18810	COG5002	protein histidine kinase activity
HEQ83_RS18815	COG0745	RESPONSE REGULATOR receiver
HEQ83_RS18845	COG0346	lactoylglutathione lyase activity
HEQ83_RS18850	COG0305	Participates in initiation and elongation during chromosome replication
HEQ83_RS18865	COG3093	addiction module antidote protein HigA
HEQ83_RS18870	COG0297	glycogen (starch) synthase activity
HEQ83_RS18880	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEQ83_RS18885	COG0438	transferase activity, transferring glycosyl groups
HEQ83_RS18905	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HEQ83_RS18910	COG4241	membrane
HEQ83_RS18920	COG5577	PFAM Coat F domain
HEQ83_RS18925	COG1733	regulation of RNA biosynthetic process
HEQ83_RS18935	COG0697	spore germination
HEQ83_RS18940	COG1621	beta-fructofuranosidase activity
HEQ83_RS18945	COG1621	beta-fructofuranosidase activity
HEQ83_RS18950	COG1802	Transcriptional regulator
HEQ83_RS18955	COG2318	DinB family
HEQ83_RS18960	COG2211	Major facilitator Superfamily
HEQ83_RS18970	COG0778	Nitroreductase
HEQ83_RS18975	COG1846	Transcriptional regulator
HEQ83_RS18980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEQ83_RS18985	COG1846	Transcriptional regulator
HEQ83_RS19010	COG0583	DNA-binding transcription factor activity
HEQ83_RS19015	COG1028	Short-chain dehydrogenase reductase Sdr
HEQ83_RS19020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEQ83_RS19025	COG0697	spore germination
HEQ83_RS19035	COG1959	2 iron, 2 sulfur cluster binding
HEQ83_RS19040	COG1396	sequence-specific DNA binding
HEQ83_RS19050	COG1331	Highly conserved protein containing a thioredoxin domain
HEQ83_RS19055	COG1266	CAAX protease self-immunity
HEQ83_RS19060	COG0477	Major facilitator Superfamily
HEQ83_RS19060	COG2814	Major facilitator Superfamily
HEQ83_RS19065	COG0346	lactoylglutathione lyase activity
HEQ83_RS19070	COG1609	Transcriptional regulator
HEQ83_RS19075	COG0708	Exodeoxyribonuclease III
HEQ83_RS19080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEQ83_RS19085	COG2169	Transcriptional regulator
HEQ83_RS19095	COG0629	single-stranded DNA binding
HEQ83_RS19105	COG0012	GTP binding
HEQ83_RS19110	COG0243	molybdopterin cofactor binding
HEQ83_RS19115	COG4481	Protein conserved in bacteria
HEQ83_RS19120	COG3949	Membrane
HEQ83_RS19135	COG1475	DNA binding
HEQ83_RS19140	COG1192	Involved in chromosome partitioning
HEQ83_RS19165	COG1847	R3H domain protein
HEQ83_RS19170	COG0706	membrane insertase activity
HEQ83_RS19195	COG0457	Tetratricopeptide repeat