locus-tag	class	description
D9777_RS00045	COG0457	Tetratricopeptide repeat
D9777_RS00055	COG4988	ABC transporter
D9777_RS00060	COG1294	oxidase, subunit
D9777_RS00065	COG1271	oxidase subunit
D9777_RS00070	COG3493	citrate carrier protein
D9777_RS00075	COG0726	polysaccharide deacetylase
D9777_RS00080	COG3842	ATPase activity
D9777_RS00085	COG2508	Transcriptional regulator
D9777_RS00090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9777_RS00100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9777_RS00110	COG4894	glucomannan catabolic process
D9777_RS00115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9777_RS00120	COG0500	methyltransferase
D9777_RS00125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9777_RS00140	COG0693	protein deglycase activity
D9777_RS00140	COG0753	catalase activity
D9777_RS00145	COG2851	Citrate transporter
D9777_RS00150	COG2273	Hydrolase Family 16
D9777_RS00155	COG3711	transcriptional antiterminator
D9777_RS00160	COG2270	Major facilitator Superfamily
D9777_RS00165	COG0513	Belongs to the DEAD box helicase family
D9777_RS00240	COG3209	COG3209 Rhs family protein
D9777_RS00250	COG0697	spore germination
D9777_RS00255	COG0589	response to stress
D9777_RS00265	COG0494	nUDIX hydrolase
D9777_RS00270	COG3507	Belongs to the glycosyl hydrolase 43 family
D9777_RS00295	COG0010	Belongs to the arginase family
D9777_RS00300	COG0833	amino acid
D9777_RS00305	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D9777_RS00310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9777_RS00320	COG2390	Transcriptional regulator
D9777_RS00325	COG0561	phosphatase activity
D9777_RS00355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9777_RS00360	COG5294	Protein conserved in bacteria
D9777_RS00365	COG0577	efflux transmembrane transporter activity
D9777_RS00370	COG1136	(ABC) transporter
D9777_RS00375	COG2205	protein histidine kinase activity
D9777_RS00380	COG0745	RESPONSE REGULATOR receiver
D9777_RS00385	COG2205	protein histidine kinase activity
D9777_RS00390	COG0745	RESPONSE REGULATOR receiver
D9777_RS00420	COG1082	Xylose isomerase domain protein TIM barrel
D9777_RS00430	COG2814	Major facilitator Superfamily
D9777_RS00460	COG1349	DNA-binding transcription factor activity
D9777_RS00465	COG0667	Aldo Keto reductase
D9777_RS00470	COG2814	Major facilitator Superfamily
D9777_RS00485	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS00490	COG2197	response regulator
D9777_RS00495	COG4585	Histidine kinase
D9777_RS00500	COG3239	Fatty acid desaturase
D9777_RS00510	COG1309	transcriptional regulator
D9777_RS00515	COG1012	belongs to the aldehyde dehydrogenase family
D9777_RS00520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D9777_RS00530	COG0640	Transcriptional regulator
D9777_RS00535	COG2814	Major facilitator Superfamily
D9777_RS00540	COG1714	RDD family
D9777_RS00550	COG0450	alkyl hydroperoxide reductase
D9777_RS00555	COG3634	alkyl hydroperoxide reductase activity
D9777_RS00560	COG3177	Filamentation induced by cAMP protein fic
D9777_RS00565	COG1113	amino acid transport
D9777_RS00575	COG2080	2 iron, 2 sulfur cluster binding
D9777_RS00590	COG2068	MobA-Related Protein
D9777_RS00595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D9777_RS00650	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D9777_RS00655	COG0667	Aldo Keto reductase
D9777_RS00660	COG0456	acetyltransferase
D9777_RS00665	COG0457	Tetratricopeptide repeat
D9777_RS00670	COG0010	Belongs to the arginase family
D9777_RS00675	COG0833	amino acid
D9777_RS00680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9777_RS00685	COG5658	integral membrane protein
D9777_RS00690	COG0640	Transcriptional regulator
D9777_RS00695	COG3829	transcription factor binding
D9777_RS00705	COG0488	(ABC) transporter
D9777_RS00720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9777_RS00725	COG3850	Histidine kinase
D9777_RS00725	COG5002	protein histidine kinase activity
D9777_RS00730	COG0745	RESPONSE REGULATOR receiver
D9777_RS00740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9777_RS00745	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9777_RS00750	COG4853	Protein conserved in bacteria
D9777_RS00755	COG4863	YycH protein
D9777_RS00760	COG5002	protein histidine kinase activity
D9777_RS00765	COG0745	RESPONSE REGULATOR receiver
D9777_RS00800	COG0346	lactoylglutathione lyase activity
D9777_RS00805	COG0305	Participates in initiation and elongation during chromosome replication
D9777_RS00820	COG3093	addiction module antidote protein HigA
D9777_RS00825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9777_RS00840	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9777_RS00845	COG0438	transferase activity, transferring glycosyl groups
D9777_RS00855	COG2112	serine threonine protein kinase
D9777_RS00865	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9777_RS00870	COG4241	membrane
D9777_RS00880	COG5577	PFAM Coat F domain
D9777_RS00885	COG1733	regulation of RNA biosynthetic process
D9777_RS00895	COG0697	spore germination
D9777_RS00900	COG1621	beta-fructofuranosidase activity
D9777_RS00905	COG1621	beta-fructofuranosidase activity
D9777_RS00910	COG1802	Transcriptional regulator
D9777_RS00915	COG2318	DinB family
D9777_RS00920	COG2211	Major facilitator Superfamily
D9777_RS00925	COG0697	spore germination
D9777_RS00930	COG0789	Transcriptional regulator
D9777_RS00935	COG0583	DNA-binding transcription factor activity
D9777_RS00945	COG2814	Major facilitator Superfamily
D9777_RS00950	COG0583	DNA-binding transcription factor activity
D9777_RS00960	COG0778	Nitroreductase
D9777_RS00965	COG1846	Transcriptional regulator
D9777_RS00970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9777_RS00975	COG1846	Transcriptional regulator
D9777_RS00980	COG2153	protein acetylation
D9777_RS00990	COG0546	phosphoglycolate phosphatase activity
D9777_RS01020	COG1404	Belongs to the peptidase S8 family
D9777_RS01030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9777_RS01035	COG0697	spore germination
D9777_RS01040	COG1078	dGTPase activity
D9777_RS01050	COG1331	Highly conserved protein containing a thioredoxin domain
D9777_RS01055	COG1266	CAAX protease self-immunity
D9777_RS01060	COG2814	Major facilitator Superfamily
D9777_RS01060	COG0477	Major facilitator Superfamily
D9777_RS01065	COG0346	lactoylglutathione lyase activity
D9777_RS01070	COG1609	Transcriptional regulator
D9777_RS01080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9777_RS01085	COG2169	Transcriptional regulator
D9777_RS01095	COG0629	single-stranded DNA binding
D9777_RS01105	COG0012	GTP binding
D9777_RS01110	COG0243	molybdopterin cofactor binding
D9777_RS01115	COG4481	Protein conserved in bacteria
D9777_RS01120	COG3949	Membrane
D9777_RS01135	COG1475	DNA binding
D9777_RS01140	COG1192	Involved in chromosome partitioning
D9777_RS01165	COG1847	R3H domain protein
D9777_RS01170	COG0706	membrane insertase activity
D9777_RS01190	COG0592	DNA-directed DNA polymerase activity
D9777_RS01195	COG2501	S4 domain
D9777_RS01210	COG0187	DNA topoisomerase II activity
D9777_RS01215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9777_RS01250	COG0516	GMP reductase activity
D9777_RS01250	COG0517	IMP dehydrogenase activity
D9777_RS01255	COG1686	Belongs to the peptidase S11 family
D9777_RS01275	COG1929	Belongs to the glycerate kinase type-1 family
D9777_RS01285	COG1428	Deoxynucleoside kinase
D9777_RS01290	COG1428	Deoxynucleoside kinase
D9777_RS01295	COG3858	chitin binding
D9777_RS01295	COG1388	LysM domain
D9777_RS01300	COG1335	isochorismatase
D9777_RS01305	COG0590	tRNA wobble adenosine to inosine editing
D9777_RS01315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9777_RS01320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9777_RS01370	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D9777_RS01375	COG3853	Toxic anion resistance protein (TelA)
D9777_RS01380	COG1982	Orn Lys Arg decarboxylase major
D9777_RS01390	COG3870	Protein conserved in bacteria
D9777_RS01395	COG1728	Protein conserved in bacteria
D9777_RS01400	COG0470	DNA polymerase III
D9777_RS01405	COG1774	PSP1 C-terminal conserved region
D9777_RS01415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9777_RS01425	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9777_RS01430	COG2002	toxin-antitoxin pair type II binding
D9777_RS01435	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9777_RS01435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9777_RS01440	COG0084	hydrolase, TatD family'
D9777_RS01445	COG3583	domain protein
D9777_RS01445	COG3584	3D domain protein
D9777_RS01450	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9777_RS01455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9777_RS01465	COG4466	Protein conserved in bacteria
D9777_RS01480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9777_RS01485	COG0251	oxidation-reduction process
D9777_RS01500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9777_RS01520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9777_RS01525	COG2002	toxin-antitoxin pair type II binding
D9777_RS01530	COG2244	polysaccharide biosynthetic process
D9777_RS01535	COG3956	TIGRFAM MazG family protein
D9777_RS01540	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9777_RS01555	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9777_RS01560	COG1098	S1 RNA binding domain
D9777_RS01575	COG2208	phosphoserine phosphatase activity
D9777_RS01580	COG2304	oxidoreductase activity
D9777_RS01585	COG0515	serine threonine protein kinase
D9777_RS01590	COG0037	tRNA processing
D9777_RS01595	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D9777_RS01600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9777_RS01615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9777_RS01620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9777_RS01625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9777_RS01630	COG0512	Glutamine amidotransferase of anthranilate synthase
D9777_RS01635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9777_RS01640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9777_RS01645	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9777_RS01650	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9777_RS01655	COG1396	sequence-specific DNA binding
D9777_RS01660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9777_RS01665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9777_RS01745	COG4463	regulation of RNA biosynthetic process
D9777_RS01750	COG3880	PFAM UvrB UvrC protein
D9777_RS01760	COG0542	response to heat
D9777_RS01765	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9777_RS01770	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9777_RS01775	COG4956	integral membrane protein (PIN domain superfamily)
D9777_RS01795	COG1045	serine acetyltransferase
D9777_RS01805	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D9777_RS01810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9777_RS01815	COG3688	RNA-binding protein containing a PIN domain
D9777_RS01820	COG1595	DNA-templated transcription, initiation
D9777_RS01830	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9777_RS01835	COG0250	Participates in transcription elongation, termination and antitermination
D9777_RS01860	COG2813	Specifically methylates the guanine in position
D9777_RS01875	COG1358	cellular component organization or biogenesis
D9777_RS01900	COG0596	Alpha beta hydrolase
D9777_RS01995	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9777_RS02010	COG0201	protein transport
D9777_RS02020	COG0024	Methionine aminopeptidase
D9777_RS02035	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9777_RS02060	COG1122	ATPase activity
D9777_RS02065	COG1122	ATPase activity
D9777_RS02070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9777_RS02090	COG2226	methyltransferase
D9777_RS02095	COG2318	DinB family
D9777_RS02105	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9777_RS02110	COG0489	protein tyrosine kinase activity
D9777_RS02120	COG2194	sulfuric ester hydrolase activity
D9777_RS02125	COG0726	polysaccharide deacetylase
D9777_RS02160	COG2856	Zn peptidase
D9777_RS02185	COG2369	cell adhesion
D9777_RS02195	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9777_RS02200	COG4653	Phage capsid family
D9777_RS02215	COG1388	LysM domain
D9777_RS02215	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9777_RS02215	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS02230	COG5444	nuclease activity
D9777_RS02235	COG0457	Tetratricopeptide repeat
D9777_RS02250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9777_RS02285	COG0738	Major facilitator superfamily
D9777_RS02290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9777_RS02305	COG0659	secondary active sulfate transmembrane transporter activity
D9777_RS02310	COG0385	Bile acid
D9777_RS02315	COG2819	hydrolase of the alpha beta superfamily
D9777_RS02320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9777_RS02325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9777_RS02330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9777_RS02335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9777_RS02335	COG2207	Transcriptional regulator
D9777_RS02340	COG3876	Protein conserved in bacteria
D9777_RS02345	COG1472	Belongs to the glycosyl hydrolase 3 family
D9777_RS02350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9777_RS02355	COG1263	PTS System
D9777_RS02355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9777_RS02365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9777_RS02370	COG1683	Conserved Protein
D9777_RS02400	COG1595	DNA-templated transcription, initiation
D9777_RS02405	COG5662	AntiSigma factor
D9777_RS02410	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9777_RS02415	COG4856	YbbR-like protein
D9777_RS02465	COG1346	cytolysis
D9777_RS02470	COG1380	Effector of murein hydrolase LrgA
D9777_RS02475	COG1846	Transcriptional regulator
D9777_RS02480	COG1113	amino acid transport
D9777_RS02485	COG1011	Hydrolase
D9777_RS02490	COG4585	Histidine kinase
D9777_RS02495	COG2197	response regulator
D9777_RS02500	COG1131	(ABC) transporter
D9777_RS02540	COG0531	amino acid
D9777_RS02565	COG0584	glycerophosphoryl diester phosphodiesterase
D9777_RS02570	COG2271	Major facilitator Superfamily
D9777_RS02585	COG2368	4-hydroxyphenylacetate
D9777_RS02595	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS02610	COG0371	Dehydrogenase
D9777_RS02620	COG1183	phosphatidylcholine synthase activity
D9777_RS02625	COG0586	Pfam SNARE associated Golgi protein
D9777_RS02630	COG0688	phosphatidylethanolamine metabolic process
D9777_RS02645	COG1301	dicarboxylic acid transport
D9777_RS02650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9777_RS02655	COG0833	amino acid
D9777_RS02660	COG2040	homocysteine
D9777_RS02665	COG1115	amino acid carrier protein
D9777_RS02670	COG2066	Belongs to the glutaminase family
D9777_RS02675	COG4191	Histidine kinase
D9777_RS02680	COG0784	Response regulator, receiver
D9777_RS02685	COG3173	Aminoglycoside phosphotransferase
D9777_RS02705	COG3773	Cell wall hydrolase
D9777_RS02715	COG3540	Alkaline phosphatase
D9777_RS02720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9777_RS02725	COG0805	protein transport
D9777_RS02735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9777_RS02740	COG0477	Major facilitator Superfamily
D9777_RS02745	COG1309	transcriptional regulator
D9777_RS02750	COG0252	asparaginase activity
D9777_RS02755	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9777_RS02760	COG3012	SEC-C Motif Domain Protein
D9777_RS02760	COG1405	negative regulation of cell septum assembly
D9777_RS02765	COG0667	Aldo Keto reductase
D9777_RS02775	COG1595	DNA-templated transcription, initiation
D9777_RS02780	COG1595	DNA-templated transcription, initiation
D9777_RS02785	COG1876	peptidase activity
D9777_RS02790	COG0457	Tetratricopeptide repeat
D9777_RS02795	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS02800	COG0366	Alpha amylase catalytic
D9777_RS02805	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9777_RS02810	COG1121	(ABC) transporter
D9777_RS02815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9777_RS02820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9777_RS02825	COG2310	stress, protein
D9777_RS02830	COG2310	stress, protein
D9777_RS02835	COG2310	stress, protein
D9777_RS02840	COG0861	Integral membrane protein TerC family
D9777_RS02850	COG3853	Toxic anion resistance protein (TelA)
D9777_RS02855	COG0477	Major facilitator Superfamily
D9777_RS02860	COG0517	IMP dehydrogenase activity
D9777_RS02860	COG4175	Glycine betaine
D9777_RS02865	COG4176	ABC-type proline glycine betaine transport system permease component
D9777_RS02870	COG2113	Glycine betaine
D9777_RS02875	COG1473	amidohydrolase
D9777_RS02880	COG1288	antiporter activity
D9777_RS02890	COG0366	Alpha amylase catalytic
D9777_RS02900	COG2814	Major facilitator Superfamily
D9777_RS02905	COG1846	Transcriptional regulator
D9777_RS02910	COG1280	lysine exporter protein (LysE YggA)
D9777_RS02915	COG3403	YqcI/YcgG family
D9777_RS02920	COG1113	amino acid transport
D9777_RS02925	COG3665	Urea carboxylase-associated protein
D9777_RS02940	COG1660	Displays ATPase and GTPase activities
D9777_RS02945	COG1082	Xylose isomerase domain protein TIM barrel
D9777_RS02950	COG2271	Major facilitator Superfamily
D9777_RS02955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9777_RS02965	COG3458	cephalosporin-C deacetylase activity
D9777_RS02970	COG3541	Predicted nucleotidyltransferase
D9777_RS02975	COG0506	proline dehydrogenase activity
D9777_RS02980	COG1012	belongs to the aldehyde dehydrogenase family
D9777_RS02985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9777_RS02990	COG2508	Transcriptional regulator
D9777_RS03000	COG1587	Uroporphyrinogen-III synthase
D9777_RS03000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9777_RS03005	COG2146	nitrite reductase [NAD(P)H] activity
D9777_RS03010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9777_RS03015	COG0243	molybdopterin cofactor binding
D9777_RS03020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9777_RS03025	COG2223	nitrite transmembrane transporter activity
D9777_RS03030	COG0523	cobalamin synthesis protein
D9777_RS03035	COG1063	alcohol dehydrogenase
D9777_RS03040	COG1714	RDD family
D9777_RS03050	COG2723	6-phospho-beta-galactosidase activity
D9777_RS03060	COG3209	COG3209 Rhs family protein
D9777_RS03065	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9777_RS03070	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9777_RS03075	COG1733	regulation of RNA biosynthetic process
D9777_RS03085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS03090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS03095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS03100	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D9777_RS03115	COG2364	Membrane
D9777_RS03120	COG1126	abc transporter atp-binding protein
D9777_RS03125	COG0765	amino acid transport
D9777_RS03130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9777_RS03135	COG0583	DNA-binding transcription factor activity
D9777_RS03140	COG0163	prenyltransferase activity
D9777_RS03145	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D9777_RS03160	COG3104	oligopeptide transport
D9777_RS03165	COG5434	Belongs to the glycosyl hydrolase 28 family
D9777_RS03175	COG0697	spore germination
D9777_RS03185	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9777_RS03190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9777_RS03195	COG0456	acetyltransferase
D9777_RS03200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9777_RS03205	COG0765	amino acid transport
D9777_RS03210	COG1126	abc transporter atp-binding protein
D9777_RS03215	COG1473	amidohydrolase
D9777_RS03220	COG2079	MmgE PrpD family protein
D9777_RS03225	COG1136	(ABC) transporter
D9777_RS03230	COG0577	efflux transmembrane transporter activity
D9777_RS03235	COG0745	RESPONSE REGULATOR receiver
D9777_RS03240	COG5002	protein histidine kinase activity
D9777_RS03240	COG3850	Histidine kinase
D9777_RS03245	COG0457	Tetratricopeptide repeat
D9777_RS03260	COG0527	aspartate kinase activity
D9777_RS03265	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9777_RS03270	COG4605	iron ion homeostasis
D9777_RS03275	COG4604	ABC transporter, ATP-binding protein
D9777_RS03280	COG4607	ABC-type enterochelin transport system periplasmic component
D9777_RS03285	COG2814	Major facilitator Superfamily
D9777_RS03290	COG1309	transcriptional regulator
D9777_RS03295	COG0778	Nitroreductase
D9777_RS03300	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9777_RS03305	COG0640	Transcriptional regulator
D9777_RS03310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9777_RS03315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9777_RS03320	COG1012	belongs to the aldehyde dehydrogenase family
D9777_RS03325	COG4975	Glucose uptake
D9777_RS03330	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS03335	COG4549	nuclear export factor GLE1
D9777_RS03340	COG2372	response to copper ion
D9777_RS03340	COG1276	copper resistance
D9777_RS03345	COG1349	DNA-binding transcription factor activity
D9777_RS03355	COG2213	PTS system mannitol-specific
D9777_RS03360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9777_RS03370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9777_RS03380	COG0561	phosphatase activity
D9777_RS03390	COG1914	H( )-stimulated, divalent metal cation uptake system
D9777_RS03400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9777_RS03405	COG1984	allophanate hydrolase subunit 2
D9777_RS03410	COG1414	Transcriptional regulator
D9777_RS03415	COG2755	lipolytic protein G-D-S-L family
D9777_RS03425	COG2329	Antibiotic biosynthesis monooxygenase
D9777_RS03430	COG0768	penicillin binding
D9777_RS03435	COG4989	oxidoreductase activity
D9777_RS03440	COG3711	transcriptional antiterminator
D9777_RS03445	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS03450	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS03455	COG1917	Cupin 2, conserved barrel domain protein
D9777_RS03460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9777_RS03465	COG3871	stress protein (general stress protein 26)
D9777_RS03475	COG2814	Major facilitator Superfamily
D9777_RS03480	COG1522	sequence-specific DNA binding
D9777_RS03485	COG0551	DNA topoisomerase type I activity
D9777_RS03485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9777_RS03490	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D9777_RS03495	COG3706	GGDEF domain
D9777_RS03500	COG5298	Protein conserved in bacteria
D9777_RS03505	COG1215	transferase activity, transferring glycosyl groups
D9777_RS03515	COG0531	amino acid
D9777_RS03520	COG0494	nUDIX hydrolase
D9777_RS03525	COG0028	Belongs to the TPP enzyme family
D9777_RS03565	COG1914	H( )-stimulated, divalent metal cation uptake system
D9777_RS03580	COG4876	unkown
D9777_RS03590	COG2076	Multidrug Resistance protein
D9777_RS03595	COG2217	Heavy metal translocating P-type atpase
D9777_RS03600	COG3729	General stress protein
D9777_RS03605	COG0662	Cupin 2, conserved barrel domain protein
D9777_RS03610	COG2329	Antibiotic biosynthesis monooxygenase
D9777_RS03615	COG3546	catalase activity
D9777_RS03620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9777_RS03625	COG3290	protein histidine kinase activity
D9777_RS03630	COG4565	transcriptional regulatory protein
D9777_RS03635	COG1301	dicarboxylic acid transport
D9777_RS03640	COG0628	permease
D9777_RS03645	COG1131	(ABC) transporter
D9777_RS03650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9777_RS03660	COG1960	acyl-CoA dehydrogenase activity
D9777_RS03675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9777_RS03680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9777_RS03690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9777_RS03695	COG0513	Belongs to the DEAD box helicase family
D9777_RS03700	COG3402	PFAM membrane-flanked domain
D9777_RS03705	COG3428	Bacterial PH domain
D9777_RS03710	COG0705	Rhomboid family
D9777_RS03720	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9777_RS03725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9777_RS03730	COG0864	Transcriptional regulator
D9777_RS03735	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9777_RS03740	COG1366	Belongs to the anti-sigma-factor antagonist family
D9777_RS03745	COG1366	Belongs to the anti-sigma-factor antagonist family
D9777_RS03750	COG2172	sigma factor antagonist activity
D9777_RS03755	COG2208	phosphoserine phosphatase activity
D9777_RS03760	COG1366	Belongs to the anti-sigma-factor antagonist family
D9777_RS03770	COG1191	sigma factor activity
D9777_RS03775	COG2208	phosphoserine phosphatase activity
D9777_RS03780	COG2183	response to ionizing radiation
D9777_RS03855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9777_RS03860	COG0477	Major facilitator Superfamily
D9777_RS03880	COG2030	dehydratase
D9777_RS03895	COG1959	2 iron, 2 sulfur cluster binding
D9777_RS03900	COG2910	NAD(P)H-binding
D9777_RS03910	COG1278	Cold shock
D9777_RS03915	COG1329	Transcriptional regulator
D9777_RS03920	COG1937	Protein conserved in bacteria
D9777_RS03925	COG2210	Belongs to the sulfur carrier protein TusA family
D9777_RS03930	COG1054	Belongs to the UPF0176 family
D9777_RS03935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9777_RS03935	COG0425	Belongs to the sulfur carrier protein TusA family
D9777_RS03940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9777_RS03940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9777_RS03945	COG0425	Belongs to the sulfur carrier protein TusA family
D9777_RS03950	COG0730	response to heat
D9777_RS03955	COG1794	racemase activity, acting on amino acids and derivatives
D9777_RS03970	COG3621	Patatin-like phospholipase
D9777_RS03980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9777_RS03990	COG0251	oxidation-reduction process
D9777_RS03995	COG0814	amino acid
D9777_RS04000	COG1473	amidohydrolase
D9777_RS04005	COG2207	Transcriptional regulator
D9777_RS04005	COG1917	Cupin 2, conserved barrel domain protein
D9777_RS04015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9777_RS04020	COG0477	Major facilitator Superfamily
D9777_RS04055	COG2318	DinB family
D9777_RS04085	COG0351	phosphomethylpyrimidine kinase
D9777_RS04100	COG1064	alcohol dehydrogenase
D9777_RS04105	COG0789	Transcriptional regulator
D9777_RS04115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9777_RS04130	COG2814	Major facilitator Superfamily
D9777_RS04135	COG1309	transcriptional regulator
D9777_RS04140	COG0697	spore germination
D9777_RS04145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9777_RS04150	COG5577	PFAM Coat F domain
D9777_RS04160	COG1063	alcohol dehydrogenase
D9777_RS04165	COG5577	PFAM Coat F domain
D9777_RS04175	COG0738	Major facilitator superfamily
D9777_RS04200	COG4585	Histidine kinase
D9777_RS04205	COG2197	response regulator
D9777_RS04210	COG2409	Drug exporters of the RND superfamily
D9777_RS04215	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D9777_RS04220	COG0488	(ABC) transporter
D9777_RS04225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9777_RS04230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9777_RS04240	COG2814	Major facilitator Superfamily
D9777_RS04245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9777_RS04255	COG0730	response to heat
D9777_RS04260	COG0456	acetyltransferase
D9777_RS04265	COG4978	Transcriptional regulator
D9777_RS04265	COG0789	Transcriptional regulator
D9777_RS04270	COG0697	spore germination
D9777_RS04275	COG1051	belongs to the nudix hydrolase family
D9777_RS04280	COG2226	methyltransferase
D9777_RS04285	COG0473	3-isopropylmalate dehydrogenase activity
D9777_RS04290	COG1802	Transcriptional regulator
D9777_RS04295	COG1819	glycosyl
D9777_RS04310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9777_RS04315	COG1388	LysM domain
D9777_RS04320	COG2814	Major facilitator Superfamily
D9777_RS04325	COG2188	Transcriptional regulator
D9777_RS04330	COG2186	Transcriptional regulator
D9777_RS04335	COG2807	transmembrane transport
D9777_RS04340	COG2076	Multidrug Resistance protein
D9777_RS04345	COG2076	Multidrug Resistance protein
D9777_RS04350	COG1309	transcriptional regulator
D9777_RS04355	COG0531	amino acid
D9777_RS04365	COG3832	glyoxalase III activity
D9777_RS04370	COG0604	alcohol dehydrogenase
D9777_RS04375	COG2814	Major facilitator Superfamily
D9777_RS04415	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9777_RS04420	COG0802	atpase or kinase
D9777_RS04425	COG1214	PFAM Peptidase M22, glycoprotease
D9777_RS04430	COG0456	acetyltransferase
D9777_RS04435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9777_RS04440	COG0488	(ABC) transporter
D9777_RS04455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9777_RS04460	COG0805	protein transport
D9777_RS04470	COG1266	CAAX protease self-immunity
D9777_RS04495	COG0457	Tetratricopeptide repeat
D9777_RS04500	COG1063	alcohol dehydrogenase
D9777_RS04505	COG2211	Major facilitator Superfamily
D9777_RS04510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9777_RS04520	COG1842	Phage shock protein A
D9777_RS04525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9777_RS04530	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D9777_RS04535	COG4260	virion core protein, lumpy skin disease virus
D9777_RS04540	COG2755	lipolytic protein G-D-S-L family
D9777_RS04540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D9777_RS04550	COG1595	DNA-templated transcription, initiation
D9777_RS04555	COG1063	alcohol dehydrogenase
D9777_RS04560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D9777_RS04565	COG0823	Involved in the tonB-independent uptake of proteins
D9777_RS04575	COG2132	Multicopper oxidase
D9777_RS04580	COG1113	amino acid transport
D9777_RS04585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9777_RS04590	COG0714	Associated with various cellular activities
D9777_RS04595	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9777_RS04600	COG1305	Transglutaminase-like
D9777_RS04650	COG4974	Belongs to the 'phage' integrase family
D9777_RS04655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9777_RS04675	COG2211	Major facilitator Superfamily
D9777_RS04690	COG2252	PERMEase
D9777_RS04695	COG3064	Membrane
D9777_RS04715	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9777_RS04720	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9777_RS04725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9777_RS04730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9777_RS04735	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9777_RS04750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9777_RS04760	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9777_RS04765	COG0138	bifunctional purine biosynthesis protein purh
D9777_RS04770	COG0151	Belongs to the GarS family
D9777_RS04780	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9777_RS04785	COG1470	cell adhesion involved in biofilm formation
D9777_RS04790	COG4496	protein, YerC YecD
D9777_RS04795	COG0069	glutamate synthase activity
D9777_RS04805	COG0210	DNA helicase
D9777_RS04815	COG4851	CamS sex pheromone cAM373 precursor
D9777_RS04820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9777_RS04825	COG1285	pathogenesis
D9777_RS04830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9777_RS04850	COG1309	transcriptional regulator
D9777_RS04855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9777_RS04860	COG1597	lipid kinase activity
D9777_RS04865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9777_RS04875	COG1131	(ABC) transporter
D9777_RS04920	COG5444	nuclease activity
D9777_RS04950	COG3546	catalase activity
D9777_RS04955	COG0454	-acetyltransferase
D9777_RS04965	COG2323	membrane
D9777_RS04975	COG0346	lactoylglutathione lyase activity
D9777_RS04985	COG1366	Belongs to the anti-sigma-factor antagonist family
D9777_RS04990	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D9777_RS04995	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D9777_RS05000	COG4208	sulfate ABC transporter
D9777_RS05010	COG5583	Uncharacterized small protein (DUF2292)
D9777_RS05015	COG0196	riboflavin kinase activity
D9777_RS05020	COG0670	Belongs to the BI1 family
D9777_RS05025	COG1846	Transcriptional regulator
D9777_RS05030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9777_RS05040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9777_RS05040	COG2124	cytochrome p450
D9777_RS05045	COG1368	sulfuric ester hydrolase activity
D9777_RS05050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D9777_RS05055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9777_RS05060	COG1442	glycosyl transferase family 8
D9777_RS05065	COG1216	Glycosyl transferase, family 2
D9777_RS05070	COG1442	glycosyl transferase family 8
D9777_RS05075	COG2223	nitrite transmembrane transporter activity
D9777_RS05080	COG0531	amino acid
D9777_RS05085	COG1012	belongs to the aldehyde dehydrogenase family
D9777_RS05090	COG0840	transmembrane signaling receptor activity
D9777_RS05095	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS05100	COG0463	Glycosyl transferase, family 2
D9777_RS05100	COG0457	Tetratricopeptide repeat
D9777_RS05105	COG0488	(ABC) transporter
D9777_RS05110	COG0789	Transcriptional regulator
D9777_RS05115	COG2814	Major facilitator Superfamily
D9777_RS05120	COG0488	(ABC) transporter
D9777_RS05125	COG0513	Belongs to the DEAD box helicase family
D9777_RS05135	COG2130	NADP-dependent
D9777_RS05150	COG3866	Pectate lyase
D9777_RS05155	COG0471	metal ion transport
D9777_RS05175	COG2972	Histidine kinase
D9777_RS05175	COG0745	RESPONSE REGULATOR receiver
D9777_RS05180	COG3279	Response regulator of the LytR AlgR family
D9777_RS05190	COG3764	Sortase (surface protein transpeptidase)
D9777_RS05195	COG3290	protein histidine kinase activity
D9777_RS05200	COG4565	transcriptional regulatory protein
D9777_RS05205	COG3181	Tripartite tricarboxylate transporter family receptor
D9777_RS05210	COG2851	Citrate transporter
D9777_RS05215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9777_RS05220	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9777_RS05230	COG2258	MOSC domain
D9777_RS05250	COG0024	Methionine aminopeptidase
D9777_RS05255	COG1263	PTS System
D9777_RS05255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9777_RS05265	COG1368	sulfuric ester hydrolase activity
D9777_RS05275	COG0071	Belongs to the small heat shock protein (HSP20) family
D9777_RS05290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9777_RS05290	COG1263	PTS System
D9777_RS05295	COG0366	Alpha amylase catalytic
D9777_RS05300	COG2188	Transcriptional regulator
D9777_RS05305	COG0778	Nitroreductase
D9777_RS05320	COG0737	Belongs to the 5'-nucleotidase family
D9777_RS05325	COG0693	protein deglycase activity
D9777_RS05330	COG1609	Transcriptional regulator
D9777_RS05345	COG2814	Major facilitator Superfamily
D9777_RS05355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9777_RS05360	COG4980	gas vesicle protein
D9777_RS05365	COG1295	ribonuclease BN
D9777_RS05370	COG0477	Major facilitator Superfamily
D9777_RS05375	COG0387	Pfam Sodium calcium exchanger
D9777_RS05385	COG0668	transmembrane transport
D9777_RS05390	COG0535	radical SAM domain protein
D9777_RS05400	COG0726	polysaccharide deacetylase
D9777_RS05405	COG2084	Dehydrogenase
D9777_RS05415	COG0598	Magnesium transport protein CorA
D9777_RS05420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9777_RS05425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9777_RS05440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9777_RS05445	COG4637	Psort location Cytoplasmic, score
D9777_RS05450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9777_RS05455	COG0022	dehydrogenase e1 component
D9777_RS05460	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9777_RS05465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9777_RS05470	COG3284	Transcriptional regulator
D9777_RS05480	COG1486	melibiose metabolic process
D9777_RS05485	COG1737	Transcriptional regulator
D9777_RS05490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9777_RS05490	COG1263	PTS System
D9777_RS05495	COG5434	Belongs to the glycosyl hydrolase 28 family
D9777_RS05500	COG1132	(ABC) transporter
D9777_RS05505	COG1132	(ABC) transporter
D9777_RS05510	COG2259	Doxx family
D9777_RS05515	COG2514	catechol 2,3-dioxygenase activity
D9777_RS05530	COG1695	Transcriptional regulator
D9777_RS05535	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9777_RS05540	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D9777_RS05545	COG3848	Pyruvate phosphate dikinase
D9777_RS05545	COG0574	Belongs to the PEP-utilizing enzyme family
D9777_RS05550	COG2732	(Barnase) inhibitor
D9777_RS05555	COG2318	DinB family
D9777_RS05560	COG2814	Major facilitator Superfamily
D9777_RS05565	COG1846	Transcriptional regulator
D9777_RS05570	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9777_RS05570	COG0392	lysyltransferase activity
D9777_RS05575	COG0384	phenazine biosynthesis protein PhzF
D9777_RS05580	COG0778	Nitroreductase
D9777_RS05595	COG1090	epimerase
D9777_RS05610	COG2814	Major facilitator Superfamily
D9777_RS05620	COG3591	Belongs to the peptidase S1B family
D9777_RS05635	COG3103	Sh3 type 3 domain protein
D9777_RS05640	COG5658	integral membrane protein
D9777_RS05645	COG0596	Alpha beta hydrolase
D9777_RS05650	COG0463	Glycosyl transferase, family 2
D9777_RS05655	COG4485	Bacterial membrane protein, YfhO
D9777_RS05660	COG1988	membrane-bound metal-dependent
D9777_RS05665	COG1194	a g-specific adenine glycosylase
D9777_RS05675	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS05695	COG1132	(ABC) transporter
D9777_RS05700	COG4129	membrane
D9777_RS05715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9777_RS05720	COG0735	belongs to the Fur family
D9777_RS05830	COG1757	Na H antiporter
D9777_RS05835	COG3340	Belongs to the peptidase S51 family
D9777_RS05845	COG0277	FAD linked oxidase domain protein
D9777_RS05855	COG0747	negative chemotaxis
D9777_RS05860	COG0601	transmembrane transport
D9777_RS05865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9777_RS05870	COG0444	Belongs to the ABC transporter superfamily
D9777_RS05875	COG4608	Belongs to the ABC transporter superfamily
D9777_RS05880	COG0753	catalase activity
D9777_RS05890	COG1116	anion transmembrane transporter activity
D9777_RS05895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9777_RS05900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9777_RS05920	COG1476	TRANSCRIPTIONal
D9777_RS05930	COG3382	B3 4 domain protein
D9777_RS05935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9777_RS05945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9777_RS05950	COG0789	Transcriptional regulator
D9777_RS05955	COG1664	Polymer-forming cytoskeletal
D9777_RS05960	COG1664	Polymer-forming cytoskeletal
D9777_RS05970	COG2766	serine protein kinase
D9777_RS05985	COG1846	Transcriptional regulator
D9777_RS05990	COG1566	PFAM secretion protein HlyD family protein
D9777_RS05995	COG2814	Major facilitator Superfamily
D9777_RS06000	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9777_RS06015	COG1725	Transcriptional regulator
D9777_RS06020	COG1131	(ABC) transporter
D9777_RS06025	COG1131	(ABC) transporter
D9777_RS06030	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9777_RS06035	COG1278	Cold shock
D9777_RS06045	COG1464	Belongs to the NlpA lipoprotein family
D9777_RS06050	COG3706	GGDEF domain
D9777_RS06055	COG1823	symporter activity
D9777_RS06075	COG5577	PFAM Coat F domain
D9777_RS06080	COG1525	nuclease
D9777_RS06080	COG0737	Belongs to the 5'-nucleotidase family
D9777_RS06080	COG4085	toxin activity
D9777_RS06085	COG3764	Sortase (surface protein transpeptidase)
D9777_RS06090	COG0564	pseudouridine synthase activity
D9777_RS06100	COG0517	IMP dehydrogenase activity
D9777_RS06105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9777_RS06110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9777_RS06110	COG3153	acetyltransferase
D9777_RS06115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9777_RS06120	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9777_RS06125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9777_RS06135	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9777_RS06140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9777_RS06145	COG4585	Histidine kinase
D9777_RS06145	COG2203	Gaf domain
D9777_RS06150	COG2197	response regulator
D9777_RS06155	COG0431	NADPH-dependent FMN reductase
D9777_RS06170	COG1388	LysM domain
D9777_RS06170	COG0791	NLP P60 protein
D9777_RS06175	COG1959	2 iron, 2 sulfur cluster binding
D9777_RS06185	COG0668	transmembrane transport
D9777_RS06190	COG2719	SpoVR family
D9777_RS06195	COG1785	Belongs to the alkaline phosphatase family
D9777_RS06200	COG1388	LysM domain
D9777_RS06200	COG0791	NLP P60 protein
D9777_RS06205	COG0583	DNA-binding transcription factor activity
D9777_RS06210	COG0372	Belongs to the citrate synthase family
D9777_RS06215	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS06220	COG0531	amino acid
D9777_RS06225	COG0733	neurotransmitter:sodium symporter activity
D9777_RS06240	COG1595	DNA-templated transcription, initiation
D9777_RS06245	COG0204	Acyl-transferase
D9777_RS06250	COG1253	flavin adenine dinucleotide binding
D9777_RS06255	COG0789	Transcriptional regulator
D9777_RS06260	COG0436	Aminotransferase
D9777_RS06265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9777_RS06270	COG1253	flavin adenine dinucleotide binding
D9777_RS06275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9777_RS06280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9777_RS06285	COG0584	glycerophosphoryl diester phosphodiesterase
D9777_RS06295	COG0668	transmembrane transport
D9777_RS06300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9777_RS06305	COG0726	polysaccharide deacetylase
D9777_RS06310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9777_RS06315	COG3226	Transcriptional regulator
D9777_RS06325	COG0589	response to stress
D9777_RS06330	COG1132	(ABC) transporter
D9777_RS06335	COG1132	(ABC) transporter
D9777_RS06340	COG0702	epimerase
D9777_RS06360	COG0189	ligase activity
D9777_RS06365	COG0189	ligase activity
D9777_RS06380	COG4335	DNA alkylation repair
D9777_RS06385	COG0561	phosphatase activity
D9777_RS06390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9777_RS06400	COG0475	glutathione-regulated potassium exporter activity
D9777_RS06405	COG0490	domain, Protein
D9777_RS06415	COG1024	Enoyl-CoA hydratase
D9777_RS06425	COG4152	abc transporter atp-binding protein
D9777_RS06430	COG1668	transmembrane transport
D9777_RS06435	COG0420	3'-5' exonuclease activity
D9777_RS06440	COG4717	serine-type aminopeptidase activity
D9777_RS06455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9777_RS06495	COG4980	gas vesicle protein
D9777_RS06510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9777_RS06515	COG0537	adenosine 5'-monophosphoramidase activity
D9777_RS06520	COG1131	(ABC) transporter
D9777_RS06525	COG4473	ABC transporter
D9777_RS06535	COG1473	amidohydrolase
D9777_RS06540	COG3069	C4-dicarboxylate transmembrane transporter activity
D9777_RS06545	COG2329	Antibiotic biosynthesis monooxygenase
D9777_RS06550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9777_RS06560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D9777_RS06565	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D9777_RS06570	COG1309	transcriptional regulator
D9777_RS06575	COG1511	domain protein
D9777_RS06580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9777_RS06590	COG1363	Peptidase, m42
D9777_RS06595	COG1301	dicarboxylic acid transport
D9777_RS06605	COG1234	tRNA 3'-trailer cleavage
D9777_RS06610	COG0095	Lipoate-protein ligase
D9777_RS06615	COG0702	epimerase
D9777_RS06620	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS06630	COG0501	Belongs to the peptidase M48B family
D9777_RS06635	COG1404	Belongs to the peptidase S8 family
D9777_RS06645	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9777_RS06650	COG0406	alpha-ribazole phosphatase activity
D9777_RS06655	COG0183	Belongs to the thiolase family
D9777_RS06660	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS06665	COG1268	BioY protein
D9777_RS06670	COG0840	transmembrane signaling receptor activity
D9777_RS06675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9777_RS06675	COG0723	plastoquinol--plastocyanin reductase activity
D9777_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS06690	COG4903	ComK protein
D9777_RS06700	COG5646	InterPro IPR014922
D9777_RS06725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9777_RS06740	COG0398	Pfam SNARE associated Golgi protein
D9777_RS06745	COG0681	Belongs to the peptidase S26 family
D9777_RS06750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9777_RS06755	COG1846	Transcriptional regulator
D9777_RS06760	COG3180	Ammonia monooxygenase
D9777_RS06765	COG2814	Major facilitator Superfamily
D9777_RS06775	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D9777_RS06780	COG2323	membrane
D9777_RS06795	COG0420	3'-5' exonuclease activity
D9777_RS06800	COG0419	ATPase involved in DNA repair
D9777_RS06805	COG1403	HNH endonuclease
D9777_RS06845	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9777_RS06860	COG0367	asparagine synthase
D9777_RS06865	COG1562	ergosterol biosynthetic process
D9777_RS06870	COG0534	Mate efflux family protein
D9777_RS06875	COG1917	Cupin 2, conserved barrel domain protein
D9777_RS06875	COG2207	Transcriptional regulator
D9777_RS06880	COG1609	Transcriptional regulator
D9777_RS06885	COG0673	inositol 2-dehydrogenase activity
D9777_RS06890	COG2318	DinB family
D9777_RS06900	COG1357	PFAM Pentapeptide repeats (8 copies)
D9777_RS06905	COG2153	protein acetylation
D9777_RS06910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9777_RS06910	COG0646	methionine synthase
D9777_RS06920	COG2996	Protein conserved in bacteria
D9777_RS06925	COG1744	ABC transporter substrate-binding protein PnrA-like
D9777_RS06930	COG0840	transmembrane signaling receptor activity
D9777_RS06935	COG2124	cytochrome p450
D9777_RS06945	COG1307	EDD domain protein, DegV family
D9777_RS06950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9777_RS06965	COG0561	phosphatase activity
D9777_RS06970	COG1073	alpha beta
D9777_RS06975	COG2151	metal-sulfur cluster biosynthetic enzyme
D9777_RS06985	COG0277	FAD linked oxidase domain protein
D9777_RS06990	COG2271	Major facilitator Superfamily
D9777_RS07000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D9777_RS07010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9777_RS07015	COG0505	Belongs to the CarA family
D9777_RS07020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9777_RS07025	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9777_RS07045	COG2267	carboxylic ester hydrolase activity
D9777_RS07055	COG1744	ABC transporter substrate-binding protein PnrA-like
D9777_RS07070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9777_RS07075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9777_RS07080	COG5504	Zn-dependent protease
D9777_RS07085	COG0444	Belongs to the ABC transporter superfamily
D9777_RS07090	COG4608	Belongs to the ABC transporter superfamily
D9777_RS07100	COG0601	transmembrane transport
D9777_RS07105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9777_RS07115	COG0180	Tryptophanyl-tRNA synthetase
D9777_RS07120	COG4166	transmembrane transport
D9777_RS07125	COG0601	transmembrane transport
D9777_RS07130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9777_RS07135	COG0444	Belongs to the ABC transporter superfamily
D9777_RS07140	COG4608	Belongs to the ABC transporter superfamily
D9777_RS07150	COG0456	acetyltransferase
D9777_RS07155	COG1393	Belongs to the ArsC family
D9777_RS07160	COG0861	Integral membrane protein TerC family
D9777_RS07165	COG4862	establishment of competence for transformation
D9777_RS07170	COG4469	Competence protein
D9777_RS07175	COG1164	Oligoendopeptidase f
D9777_RS07180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9777_RS07185	COG2346	COG2346, Truncated hemoglobins
D9777_RS07190	COG0741	lytic transglycosylase activity
D9777_RS07195	COG4116	CYTH
D9777_RS07205	COG2357	RelA SpoT domain protein
D9777_RS07210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9777_RS07215	COG0564	pseudouridine synthase activity
D9777_RS07230	COG0475	glutathione-regulated potassium exporter activity
D9777_RS07230	COG0569	domain protein
D9777_RS07235	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9777_RS07240	COG0352	thiamine-phosphate diphosphorylase activity
D9777_RS07245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9777_RS07250	COG2104	thiamine diphosphate biosynthetic process
D9777_RS07260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9777_RS07265	COG0351	phosphomethylpyrimidine kinase
D9777_RS07270	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9777_RS07325	COG0210	DNA helicase
D9777_RS07345	COG1131	(ABC) transporter
D9777_RS07355	COG2153	protein acetylation
D9777_RS07365	COG2382	esterase
D9777_RS07370	COG0626	cystathionine gamma-synthase activity
D9777_RS07375	COG0626	cystathionine gamma-synthase activity
D9777_RS07385	COG0582	viral genome integration into host DNA
D9777_RS07505	COG0740	serine-type endopeptidase activity
D9777_RS07545	COG3953	SLT domain
D9777_RS07545	COG5280	Phage tail tape measure protein TP901
D9777_RS07555	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9777_RS07555	COG3942	CHAP domain
D9777_RS07560	COG5434	Belongs to the glycosyl hydrolase 28 family
D9777_RS07590	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9777_RS07590	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS07660	COG5444	nuclease activity
D9777_RS07685	COG0135	phosphoribosylanthranilate isomerase activity
D9777_RS07690	COG0135	phosphoribosylanthranilate isomerase activity
D9777_RS07700	COG2367	Beta-lactamase
D9777_RS07705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9777_RS07710	COG0477	Major facilitator Superfamily
D9777_RS07715	COG1846	Transcriptional regulator
D9777_RS07725	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9777_RS07730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9777_RS07735	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9777_RS07740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9777_RS07740	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9777_RS07745	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9777_RS07780	COG1285	pathogenesis
D9777_RS07795	COG2205	protein histidine kinase activity
D9777_RS07805	COG3383	formate dehydrogenase (NAD+) activity
D9777_RS07810	COG2427	Protein of unknown function (DUF1641)
D9777_RS07815	COG2124	cytochrome p450
D9777_RS07820	COG1819	glycosyl
D9777_RS07830	COG1587	Uroporphyrinogen-III synthase
D9777_RS07835	COG0390	transport system, permease component
D9777_RS07840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9777_RS07845	COG0697	spore germination
D9777_RS07850	COG4297	protein containing double-stranded beta helix domain
D9777_RS07860	COG1252	NADH dehydrogenase
D9777_RS07870	COG2211	Major facilitator Superfamily
D9777_RS07875	COG1609	Transcriptional regulator
D9777_RS07880	COG0246	Mannitol dehydrogenase
D9777_RS07885	COG2721	sulfolactate sulfo-lyase activity
D9777_RS07890	COG0730	response to heat
D9777_RS07895	COG2318	DinB family
D9777_RS07900	COG0457	Tetratricopeptide repeat
D9777_RS07905	COG1388	LysM domain
D9777_RS07905	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS07905	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9777_RS07915	COG4195	phage-related replication protein
D9777_RS07920	COG3546	catalase activity
D9777_RS07925	COG2856	Zn peptidase
D9777_RS07930	COG1396	sequence-specific DNA binding
D9777_RS07940	COG1522	sequence-specific DNA binding
D9777_RS07945	COG1484	DNA-dependent DNA replication
D9777_RS07960	COG1595	DNA-templated transcription, initiation
D9777_RS07965	COG5484	DNA packaging
D9777_RS07965	COG3728	DNA packaging
D9777_RS07970	COG1783	phage Terminase large subunit
D9777_RS07975	COG5518	Phage portal protein
D9777_RS07980	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9777_RS07985	COG4653	Phage capsid family
D9777_RS08035	COG3953	SLT domain
D9777_RS08035	COG3953	SLT domain
D9777_RS08035	COG5412	phage tail tape measure protein
D9777_RS08035	COG3953	SLT domain
D9777_RS08035	COG5412	phage tail tape measure protein
D9777_RS08035	COG5412	phage tail tape measure protein
D9777_RS08040	COG1652	LysM domain
D9777_RS08045	COG4193	domain, Protein
D9777_RS08055	COG3628	GPW Gp25 family protein
D9777_RS08060	COG3299	homolog of phage Mu protein gp47
D9777_RS08065	COG3778	Protein conserved in bacteria
D9777_RS08105	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9777_RS08105	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS08120	COG0306	phosphate transporter
D9777_RS08125	COG1392	Phosphate transport regulator
D9777_RS08130	COG0531	amino acid
D9777_RS08135	COG0346	lactoylglutathione lyase activity
D9777_RS08140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9777_RS08145	COG0463	Glycosyl transferase, family 2
D9777_RS08150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9777_RS08155	COG0477	Major facilitator Superfamily
D9777_RS08160	COG2362	D-Aminopeptidase
D9777_RS08165	COG0601	transmembrane transport
D9777_RS08170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9777_RS08175	COG0444	Belongs to the ABC transporter superfamily
D9777_RS08180	COG4166	transmembrane transport
D9777_RS08185	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9777_RS08190	COG4948	Mandelate Racemase Muconate Lactonizing
D9777_RS08195	COG0791	NLP P60 protein
D9777_RS08200	COG4608	Belongs to the ABC transporter superfamily
D9777_RS08205	COG2706	6-phosphogluconolactonase activity
D9777_RS08210	COG1834	amidinotransferase
D9777_RS08215	COG1607	acyl-coa hydrolase
D9777_RS08220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9777_RS08225	COG2076	Multidrug Resistance protein
D9777_RS08230	COG2076	Multidrug Resistance protein
D9777_RS08235	COG0788	formyltetrahydrofolate deformylase activity
D9777_RS08240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9777_RS08250	COG1764	response to oxidative stress
D9777_RS08255	COG1846	Transcriptional regulator
D9777_RS08260	COG1764	response to oxidative stress
D9777_RS08275	COG0457	Tetratricopeptide repeat
D9777_RS08275	COG0463	Glycosyl transferase, family 2
D9777_RS08285	COG2814	Major facilitator Superfamily
D9777_RS08300	COG1404	Belongs to the peptidase S8 family
D9777_RS08305	COG1366	Belongs to the anti-sigma-factor antagonist family
D9777_RS08310	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9777_RS08315	COG1122	ATPase activity
D9777_RS08320	COG4721	ABC-type cobalt transport system, permease component
D9777_RS08325	COG3858	chitin binding
D9777_RS08325	COG1388	LysM domain
D9777_RS08345	COG2239	Acts as a magnesium transporter
D9777_RS08350	COG0789	Transcriptional regulator
D9777_RS08365	COG1846	Transcriptional regulator
D9777_RS08370	COG0726	polysaccharide deacetylase
D9777_RS08375	COG1793	dna ligase
D9777_RS08375	COG3285	dna ligase
D9777_RS08380	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9777_RS08385	COG0586	Pfam SNARE associated Golgi protein
D9777_RS08390	COG0861	Integral membrane protein TerC family
D9777_RS08395	COG1191	sigma factor activity
D9777_RS08420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9777_RS08425	COG2323	membrane
D9777_RS08435	COG3594	Acyltransferase
D9777_RS08440	COG5002	protein histidine kinase activity
D9777_RS08445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9777_RS08460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9777_RS08465	COG0436	Aminotransferase
D9777_RS08495	COG3852	Histidine kinase
D9777_RS08500	COG1846	Transcriptional regulator
D9777_RS08505	COG1360	Flagellar Motor Protein
D9777_RS08510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9777_RS08515	COG0542	response to heat
D9777_RS08525	COG3949	Membrane
D9777_RS08540	COG0720	synthase
D9777_RS08545	COG0602	queuosine metabolic process
D9777_RS08550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9777_RS08555	COG1733	regulation of RNA biosynthetic process
D9777_RS08560	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS08610	COG4873	Protein conserved in bacteria
D9777_RS08620	COG3773	Cell wall hydrolase
D9777_RS08625	COG2244	polysaccharide biosynthetic process
D9777_RS08630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9777_RS08635	COG2217	Heavy metal translocating P-type atpase
D9777_RS08640	COG0006	proline dipeptidase activity
D9777_RS08645	COG1609	Transcriptional regulator
D9777_RS08650	COG3711	transcriptional antiterminator
D9777_RS08655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9777_RS08655	COG1263	PTS System
D9777_RS08655	COG2190	(PTS) system
D9777_RS08660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9777_RS08665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9777_RS08675	COG1533	DNA photolyase activity
D9777_RS08680	COG0840	transmembrane signaling receptor activity
D9777_RS08685	COG2084	Dehydrogenase
D9777_RS08700	COG0347	Belongs to the P(II) protein family
D9777_RS08705	COG2340	Cysteine-rich secretory protein family
D9777_RS08710	COG0768	penicillin binding
D9777_RS08715	COG4191	Histidine kinase
D9777_RS08720	COG0436	Aminotransferase
D9777_RS08730	COG0835	chemotaxis
D9777_RS08730	COG0784	Response regulator, receiver
D9777_RS08740	COG2814	Major facilitator Superfamily
D9777_RS08745	COG1376	ErfK ybiS ycfS ynhG family protein
D9777_RS08750	COG1408	metallophosphoesterase
D9777_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS08765	COG2200	EAL domain
D9777_RS08770	COG4703	Protein of unknown function (DUF1797)
D9777_RS08775	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D9777_RS08785	COG0517	IMP dehydrogenase activity
D9777_RS08790	COG0583	DNA-binding transcription factor activity
D9777_RS08795	COG0716	FMN binding
D9777_RS08805	COG0716	FMN binding
D9777_RS08825	COG0668	transmembrane transport
D9777_RS08830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9777_RS08850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9777_RS08855	COG0303	'Molybdopterin
D9777_RS08860	COG1763	Mo-molybdopterin cofactor biosynthetic process
D9777_RS08865	COG0314	molybdopterin synthase activity
D9777_RS08870	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D9777_RS08880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9777_RS08885	COG1136	(ABC) transporter
D9777_RS08890	COG0577	efflux transmembrane transporter activity
D9777_RS08895	COG1349	DNA-binding transcription factor activity
D9777_RS08900	COG1105	Belongs to the carbohydrate kinase PfkB family
D9777_RS08905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9777_RS08905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9777_RS08905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9777_RS08910	COG0681	Belongs to the peptidase S26 family
D9777_RS08920	COG0488	(ABC) transporter
D9777_RS08925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9777_RS08930	COG2309	aminopeptidase activity
D9777_RS08940	COG1077	Cell shape determining protein MreB Mrl
D9777_RS08950	COG2002	toxin-antitoxin pair type II binding
D9777_RS08955	COG3852	Histidine kinase
D9777_RS08960	COG2105	PFAM AIG2 family protein
D9777_RS08960	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D9777_RS08965	COG0569	domain protein
D9777_RS08975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9777_RS08985	COG0561	phosphatase activity
D9777_RS08990	COG0242	peptide deformylase activity
D9777_RS09000	COG0497	DNA recombination
D9777_RS09015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS09015	COG4221	oxidoreductase activity
D9777_RS09015	COG3321	synthase
D9777_RS09015	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS09020	COG4221	oxidoreductase activity
D9777_RS09020	COG3321	synthase
D9777_RS09020	COG0300	oxidoreductase activity
D9777_RS09020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS09025	COG3321	synthase
D9777_RS09025	COG4221	oxidoreductase activity
D9777_RS09025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS09025	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS09030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS09030	COG3321	synthase
D9777_RS09030	COG0300	oxidoreductase activity
D9777_RS09030	COG4221	oxidoreductase activity
D9777_RS09035	COG4221	oxidoreductase activity
D9777_RS09035	COG3321	synthase
D9777_RS09035	COG0300	oxidoreductase activity
D9777_RS09035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS09040	COG4221	oxidoreductase activity
D9777_RS09040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS09040	COG3321	synthase
D9777_RS09040	COG0300	oxidoreductase activity
D9777_RS09045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS09045	COG3321	synthase
D9777_RS09045	COG4221	oxidoreductase activity
D9777_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS09050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9777_RS09055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9777_RS09060	COG0022	dehydrogenase e1 component
D9777_RS09065	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9777_RS09070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9777_RS09075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9777_RS09090	COG1982	Orn Lys Arg decarboxylase major
D9777_RS09115	COG0483	inositol monophosphate 1-phosphatase activity
D9777_RS09125	COG3227	Zinc metalloprotease (Elastase)
D9777_RS09140	COG1595	DNA-templated transcription, initiation
D9777_RS09160	COG1217	gtp-binding protein TYPA
D9777_RS09170	COG4896	Protein conserved in bacteria
D9777_RS09180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D9777_RS09185	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9777_RS09190	COG2066	Belongs to the glutaminase family
D9777_RS09200	COG0772	Belongs to the SEDS family
D9777_RS09205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9777_RS09220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9777_RS09220	COG2010	Cytochrome c
D9777_RS09225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9777_RS09230	COG1845	cytochrome c oxidase, subunit III
D9777_RS09235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9777_RS09240	COG3336	cytochrome c oxidase
D9777_RS09250	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D9777_RS09255	COG2340	Cysteine-rich secretory protein family
D9777_RS09270	COG3679	Belongs to the UPF0342 family
D9777_RS09285	COG0742	ribosomal rna small subunit methyltransferase
D9777_RS09295	COG3314	Sporulation integral membrane protein YlbJ
D9777_RS09300	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9777_RS09305	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9777_RS09315	COG1399	metal-binding, possibly nucleic acid-binding protein
D9777_RS09335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9777_RS09355	COG4839	cell division protein FtsL
D9777_RS09360	COG0768	penicillin binding
D9777_RS09365	COG0768	penicillin binding
D9777_RS09385	COG0772	Belongs to the SEDS family
D9777_RS09400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9777_RS09405	COG0849	cell division
D9777_RS09410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9777_RS09415	COG1404	Belongs to the peptidase S8 family
D9777_RS09415	COG4412	M6 family metalloprotease domain protein
D9777_RS09425	COG1191	sigma factor activity
D9777_RS09430	COG1191	sigma factor activity
D9777_RS09435	COG1119	ATPase activity
D9777_RS09440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9777_RS09445	COG1873	PFAM PRC-barrel domain
D9777_RS09450	COG1496	oxidoreductase activity
D9777_RS09455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9777_RS09465	COG0762	integral membrane protein
D9777_RS09470	COG2302	S4 RNA-binding domain
D9777_RS09475	COG3599	regulation of cell shape
D9777_RS09485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9777_RS09490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9777_RS09500	COG0564	pseudouridine synthase activity
D9777_RS09510	COG2233	PERMEase
D9777_RS09520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9777_RS09525	COG0505	Belongs to the CarA family
D9777_RS09530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9777_RS09545	COG0284	orotidine-5'-phosphate decarboxylase activity
D9777_RS09550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9777_RS09560	COG0306	phosphate transporter
D9777_RS09575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9777_RS09580	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D9777_RS09585	COG1648	precorrin-2 dehydrogenase activity
D9777_RS09600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9777_RS09605	COG1561	YicC-like family, N-terminal region
D9777_RS09615	COG0194	GDP metabolic process
D9777_RS09625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9777_RS09630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9777_RS09635	COG0242	peptide deformylase activity
D9777_RS09645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9777_RS09645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9777_RS09655	COG0631	protein serine/threonine phosphatase activity
D9777_RS09660	COG2815	serine threonine protein kinase
D9777_RS09660	COG0515	serine threonine protein kinase
D9777_RS09670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9777_RS09675	COG1564	THIamine pyrophosphokinase
D9777_RS09690	COG1302	Protein conserved in bacteria
D9777_RS09695	COG1461	Dihydroxyacetone kinase
D9777_RS09700	COG1760	l-serine dehydratase
D9777_RS09705	COG1760	l-serine dehydratase
D9777_RS09710	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9777_RS09725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9777_RS09730	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS09745	COG1196	nuclear chromosome segregation
D9777_RS09750	COG0552	protein localization to endoplasmic reticulum
D9777_RS09765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9777_RS09775	COG1837	Belongs to the UPF0109 family
D9777_RS09800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9777_RS09815	COG2257	FlhB HrpN YscU SpaS Family
D9777_RS09825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9777_RS09830	COG0758	DNA mediated transformation
D9777_RS09835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9777_RS09845	COG4974	Belongs to the 'phage' integrase family
D9777_RS09865	COG1815	bacterial-type flagellum-dependent cell motility
D9777_RS09870	COG1558	bacterial-type flagellum-dependent cell motility
D9777_RS09875	COG1677	Flagellar hook-basal body complex protein FliE
D9777_RS09880	COG1766	The M ring may be actively involved in energy transduction
D9777_RS09885	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9777_RS09890	COG1317	bacterial-type flagellum organization
D9777_RS09895	COG1157	protein secretion by the type III secretion system
D9777_RS09900	COG2882	bacterial-type flagellum organization
D9777_RS09905	COG3334	PFAM MgtE intracellular
D9777_RS09910	COG3144	bacterial-type flagellum assembly
D9777_RS09915	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9777_RS09920	COG4786	Flagellar basal body rod
D9777_RS09925	COG1582	Flagellar protein (FlbD)
D9777_RS09930	COG1580	Controls the rotational direction of flagella during chemotaxis
D9777_RS09935	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9777_RS09940	COG1776	CheC inhibitor of MCP methylation
D9777_RS09940	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9777_RS09945	COG2201	protein-glutamate methylesterase activity
D9777_RS09950	COG3190	flagellar
D9777_RS09955	COG1338	Plays a role in the flagellum-specific transport system
D9777_RS09960	COG1987	bacterial-type flagellum assembly
D9777_RS09965	COG1684	flagellar biosynthetic protein fliR
D9777_RS09970	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9777_RS09975	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9777_RS09980	COG1419	protein localization to endoplasmic reticulum
D9777_RS09985	COG0455	bacterial-type flagellum organization
D9777_RS09990	COG2201	protein-glutamate methylesterase activity
D9777_RS09995	COG2198	Histidine kinase
D9777_RS09995	COG0643	Histidine kinase
D9777_RS10000	COG0835	chemotaxis
D9777_RS10005	COG1776	CheC inhibitor of MCP methylation
D9777_RS10015	COG1191	sigma factor activity
D9777_RS10045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9777_RS10050	COG4589	Belongs to the CDS family
D9777_RS10060	COG0750	zinc metalloprotease
D9777_RS10080	COG0195	Participates in both transcription termination and antitermination
D9777_RS10085	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9777_RS10090	COG1358	cellular component organization or biogenesis
D9777_RS10100	COG1550	Protein conserved in bacteria
D9777_RS10115	COG0196	riboflavin kinase activity
D9777_RS10130	COG0726	polysaccharide deacetylase
D9777_RS10135	COG0612	Peptidase, M16
D9777_RS10140	COG1873	PFAM PRC-barrel domain
D9777_RS10145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9777_RS10150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9777_RS10155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9777_RS10160	COG0527	aspartate kinase activity
D9777_RS10170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9777_RS10175	COG0740	serine-type endopeptidase activity
D9777_RS10185	COG4980	gas vesicle protein
D9777_RS10185	COG1674	ftsk spoiiie
D9777_RS10190	COG2188	Transcriptional regulator
D9777_RS10195	COG2814	Major facilitator Superfamily
D9777_RS10200	COG1846	Transcriptional regulator
D9777_RS10205	COG2409	Drug exporters of the RND superfamily
D9777_RS10205	COG1033	growth of symbiont in host cell
D9777_RS10210	COG0612	Peptidase, M16
D9777_RS10215	COG0612	Peptidase, M16
D9777_RS10220	COG0300	oxidoreductase activity
D9777_RS10235	COG1426	Protein conserved in bacteria
D9777_RS10240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9777_RS10255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9777_RS10265	COG1692	metallophosphoesterase
D9777_RS10270	COG2359	stage V sporulation protein S
D9777_RS10290	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9777_RS10365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS10370	COG3425	synthase
D9777_RS10375	COG1024	Enoyl-CoA hydratase
D9777_RS10380	COG1024	Enoyl-CoA hydratase
D9777_RS10385	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS10385	COG0300	oxidoreductase activity
D9777_RS10385	COG3321	synthase
D9777_RS10385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS10385	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS10390	COG4221	oxidoreductase activity
D9777_RS10390	COG0300	oxidoreductase activity
D9777_RS10390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS10390	COG3321	synthase
D9777_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS10395	COG3321	synthase
D9777_RS10395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9777_RS10395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS10395	COG3321	synthase
D9777_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS10395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS10395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9777_RS10395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS10395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS10400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS10400	COG4221	oxidoreductase activity
D9777_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS10400	COG3321	synthase
D9777_RS10405	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D9777_RS10405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D9777_RS10405	COG3321	synthase
D9777_RS10405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS10410	COG2124	cytochrome p450
D9777_RS10415	COG3209	COG3209 Rhs family protein
D9777_RS10420	COG3619	membrane
D9777_RS10430	COG1404	Belongs to the peptidase S8 family
D9777_RS10440	COG4195	phage-related replication protein
D9777_RS10445	COG1764	response to oxidative stress
D9777_RS10455	COG2076	Multidrug Resistance protein
D9777_RS10495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9777_RS10500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9777_RS10505	COG4112	unkown
D9777_RS10510	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9777_RS10530	COG1525	nuclease
D9777_RS10535	COG5444	nuclease activity
D9777_RS10575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9777_RS10585	COG0457	Tetratricopeptide repeat
D9777_RS10610	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9777_RS10610	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS10620	COG5434	Belongs to the glycosyl hydrolase 28 family
D9777_RS10635	COG2433	Pfam Transposase IS66
D9777_RS10760	COG4373	Mu-like prophage FluMu protein gp28
D9777_RS10795	COG0776	regulation of translation
D9777_RS10865	COG0210	DNA helicase
D9777_RS10915	COG3655	Transcriptional regulator
D9777_RS11005	COG3655	Transcriptional regulator
D9777_RS11085	COG4474	Belongs to the UPF0398 family
D9777_RS11125	COG1793	dna ligase
D9777_RS11130	COG2135	peptidase activity
D9777_RS11145	COG4195	phage-related replication protein
D9777_RS11150	COG3420	alginic acid biosynthetic process
D9777_RS11150	COG5434	Belongs to the glycosyl hydrolase 28 family
D9777_RS11175	COG2887	Belongs to the helicase family. UvrD subfamily
D9777_RS11185	COG0305	Participates in initiation and elongation during chromosome replication
D9777_RS11190	COG0358	DNA primase activity
D9777_RS11195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9777_RS11200	COG0587	DNA-directed DNA polymerase activity
D9777_RS11205	COG3584	3D domain protein
D9777_RS11215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9777_RS11335	COG1780	Probably involved in ribonucleotide reductase function
D9777_RS11340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9777_RS11370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9777_RS11375	COG0756	dUTP diphosphatase activity
D9777_RS11405	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D9777_RS11410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9777_RS11445	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9777_RS11485	COG3331	DNA recombination
D9777_RS11495	COG0464	growth
D9777_RS11500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9777_RS11505	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9777_RS11510	COG0789	Transcriptional regulator
D9777_RS11515	COG0174	glutamine synthetase
D9777_RS11545	COG2211	Major facilitator Superfamily
D9777_RS11550	COG3507	Belongs to the glycosyl hydrolase 43 family
D9777_RS11570	COG3848	Pyruvate phosphate dikinase
D9777_RS11570	COG0574	Belongs to the PEP-utilizing enzyme family
D9777_RS11595	COG2378	regulation of single-species biofilm formation
D9777_RS11600	COG2318	DinB family
D9777_RS11605	COG1064	alcohol dehydrogenase
D9777_RS11630	COG0456	acetyltransferase
D9777_RS11680	COG3397	chitin binding
D9777_RS11690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9777_RS11700	COG5434	Belongs to the glycosyl hydrolase 28 family
D9777_RS11710	COG0756	dUTP diphosphatase activity
D9777_RS11715	COG4195	phage-related replication protein
D9777_RS11745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9777_RS11755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9777_RS11775	COG0785	Cytochrome C biogenesis protein
D9777_RS11780	COG2201	protein-glutamate methylesterase activity
D9777_RS11785	COG4846	Membrane protein involved in cytochrome C biogenesis
D9777_RS11795	COG0071	Belongs to the small heat shock protein (HSP20) family
D9777_RS11810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9777_RS11815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9777_RS11835	COG0824	Thioesterase
D9777_RS11845	COG4841	protein insertion into membrane
D9777_RS11855	COG1832	CoA-binding protein
D9777_RS11860	COG0187	DNA topoisomerase II activity
D9777_RS11865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9777_RS11875	COG1115	amino acid carrier protein
D9777_RS11885	COG1063	alcohol dehydrogenase
D9777_RS11890	COG0800	Aldolase
D9777_RS11895	COG1312	Catalyzes the dehydration of D-mannonate
D9777_RS11900	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS11905	COG1609	Transcriptional regulator
D9777_RS11910	COG2271	Major facilitator Superfamily
D9777_RS11960	COG2205	protein histidine kinase activity
D9777_RS11965	COG0745	RESPONSE REGULATOR receiver
D9777_RS11975	COG3507	Belongs to the glycosyl hydrolase 43 family
D9777_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS12005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9777_RS12010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9777_RS12015	COG2610	gluconate transmembrane transporter activity
D9777_RS12020	COG2124	cytochrome p450
D9777_RS12040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9777_RS12050	COG2246	polysaccharide biosynthetic process
D9777_RS12055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9777_RS12060	COG0586	Pfam SNARE associated Golgi protein
D9777_RS12065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9777_RS12070	COG1024	Enoyl-CoA hydratase
D9777_RS12075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9777_RS12080	COG0511	ligase activity, forming carbon-carbon bonds
D9777_RS12085	COG0439	Biotin carboxylase
D9777_RS12090	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS12095	COG1960	acyl-CoA dehydrogenase activity
D9777_RS12100	COG1649	PFAM Uncharacterised BCR, COG1649
D9777_RS12110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D9777_RS12110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS12115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS12120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS12125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS12140	COG2027	D-alanyl-D-alanine carboxypeptidase
D9777_RS12145	COG2017	converts alpha-aldose to the beta-anomer
D9777_RS12150	COG0534	Mate efflux family protein
D9777_RS12165	COG0582	viral genome integration into host DNA
D9777_RS12170	COG0166	Belongs to the GPI family
D9777_RS12175	COG0405	Gamma-glutamyltransferase
D9777_RS12180	COG2814	Major facilitator Superfamily
D9777_RS12185	COG0640	Transcriptional regulator
D9777_RS12190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9777_RS12200	COG0604	alcohol dehydrogenase
D9777_RS12210	COG0493	'glutamate synthase
D9777_RS12215	COG0067	glutamate synthase
D9777_RS12215	COG0070	glutamate synthase
D9777_RS12215	COG0069	glutamate synthase activity
D9777_RS12220	COG0583	DNA-binding transcription factor activity
D9777_RS12225	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9777_RS12240	COG0300	oxidoreductase activity
D9777_RS12245	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9777_RS12255	COG2814	Major facilitator Superfamily
D9777_RS12260	COG1070	Carbohydrate kinase
D9777_RS12265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9777_RS12270	COG0243	molybdopterin cofactor binding
D9777_RS12305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9777_RS12310	COG0662	Cupin 2, conserved barrel domain protein
D9777_RS12310	COG2207	Transcriptional regulator
D9777_RS12315	COG1309	transcriptional regulator
D9777_RS12320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9777_RS12330	COG0640	Transcriptional regulator
D9777_RS12335	COG0741	lytic transglycosylase activity
D9777_RS12340	COG2322	membrane
D9777_RS12355	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9777_RS12365	COG3584	3D domain protein
D9777_RS12365	COG1388	LysM domain
D9777_RS12370	COG0514	ATP-dependent DNA helicase (RecQ)
D9777_RS12380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9777_RS12385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9777_RS12400	COG0071	Belongs to the small heat shock protein (HSP20) family
D9777_RS12430	COG1012	belongs to the aldehyde dehydrogenase family
D9777_RS12435	COG1657	PFAM Prenyltransferase squalene oxidase
D9777_RS12440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9777_RS12445	COG0733	neurotransmitter:sodium symporter activity
D9777_RS12450	COG0385	Bile acid
D9777_RS12455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9777_RS12460	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9777_RS12470	COG4548	von Willebrand factor, type A
D9777_RS12475	COG0714	Associated with various cellular activities
D9777_RS12480	COG2032	superoxide dismutase activity
D9777_RS12485	COG1388	LysM domain
D9777_RS12485	COG0791	NLP P60 protein
D9777_RS12490	COG1819	glycosyl
D9777_RS12495	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9777_RS12500	COG0534	Mate efflux family protein
D9777_RS12510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9777_RS12515	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9777_RS12525	COG2962	Rard protein
D9777_RS12540	COG1942	4-Oxalocrotonate Tautomerase
D9777_RS12550	COG1733	regulation of RNA biosynthetic process
D9777_RS12555	COG0778	Nitroreductase
D9777_RS12560	COG0400	carboxylic ester hydrolase activity
D9777_RS12565	COG0346	lactoylglutathione lyase activity
D9777_RS12575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9777_RS12585	COG2723	6-phospho-beta-galactosidase activity
D9777_RS12590	COG2188	Transcriptional regulator
D9777_RS12595	COG0793	Belongs to the peptidase S41A family
D9777_RS12595	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS12600	COG2226	methyltransferase
D9777_RS12610	COG1876	peptidase activity
D9777_RS12630	COG0671	phosphoesterase, PA-phosphatase related
D9777_RS12660	COG1509	lysine 2,3-aminomutase activity
D9777_RS12665	COG0456	acetyltransferase
D9777_RS12670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9777_RS12675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9777_RS12680	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9777_RS12685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9777_RS12695	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D9777_RS12705	COG0456	acetyltransferase
D9777_RS12710	COG0463	Glycosyl transferase, family 2
D9777_RS12725	COG4641	Protein conserved in bacteria
D9777_RS12735	COG1086	Polysaccharide biosynthesis protein
D9777_RS12795	COG1388	LysM domain
D9777_RS12800	COG0457	Tetratricopeptide repeat
D9777_RS12815	COG3391	amine dehydrogenase activity
D9777_RS12890	COG3655	Transcriptional regulator
D9777_RS12925	COG5444	nuclease activity
D9777_RS12930	COG4282	regulation of fungal-type cell wall biogenesis
D9777_RS12955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9777_RS12975	COG1846	Transcriptional regulator
D9777_RS12980	COG4698	Protein conserved in bacteria
D9777_RS12985	COG2755	lipolytic protein G-D-S-L family
D9777_RS12990	COG1999	signal sequence binding
D9777_RS13000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9777_RS13005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9777_RS13010	COG1272	protein, Hemolysin III
D9777_RS13020	COG0204	Acyl-transferase
D9777_RS13025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9777_RS13040	COG2521	methyltransferase
D9777_RS13040	COG2136	Putative SAM-dependent methyltransferase
D9777_RS13055	COG1413	lyase activity
D9777_RS13060	COG1418	mRNA catabolic process
D9777_RS13065	COG0386	Belongs to the glutathione peroxidase family
D9777_RS13075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9777_RS13085	COG1278	Cold shock
D9777_RS13105	COG0328	RNA-DNA hybrid ribonuclease activity
D9777_RS13110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9777_RS13115	COG0328	RNA-DNA hybrid ribonuclease activity
D9777_RS13125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9777_RS13140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9777_RS13150	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9777_RS13155	COG3424	synthase
D9777_RS13185	COG1335	isochorismatase
D9777_RS13190	COG2233	PERMEase
D9777_RS13200	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9777_RS13205	COG1199	ATP-dependent helicase activity
D9777_RS13220	COG0116	Belongs to the methyltransferase superfamily
D9777_RS13250	COG3359	exonuclease
D9777_RS13255	COG1111	helicase
D9777_RS13255	COG1205	dead DEAH box helicase
D9777_RS13260	COG2190	(PTS) system
D9777_RS13265	COG0071	Belongs to the small heat shock protein (HSP20) family
D9777_RS13305	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9777_RS13305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9777_RS13315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9777_RS13320	COG3935	DnaD domain protein
D9777_RS13330	COG0436	Aminotransferase
D9777_RS13335	COG5353	protein conserved in bacteria
D9777_RS13345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9777_RS13345	COG1199	ATP-dependent helicase activity
D9777_RS13375	COG0438	transferase activity, transferring glycosyl groups
D9777_RS13380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9777_RS13395	COG1694	Mazg nucleotide pyrophosphohydrolase
D9777_RS13400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9777_RS13405	COG2140	Oxalate decarboxylase
D9777_RS13415	COG4347	Protein of unknown function (DUF1405)
D9777_RS13420	COG2010	Cytochrome c
D9777_RS13420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9777_RS13425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9777_RS13430	COG0723	plastoquinol--plastocyanin reductase activity
D9777_RS13445	COG0457	Tetratricopeptide repeat
D9777_RS13455	COG0287	Prephenate dehydrogenase
D9777_RS13490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9777_RS13495	COG4401	Chorismate mutase type I
D9777_RS13510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9777_RS13515	COG0105	UTP biosynthetic process
D9777_RS13520	COG0142	geranyltranstransferase activity
D9777_RS13530	COG0142	geranyltranstransferase activity
D9777_RS13545	COG0776	regulation of translation
D9777_RS13550	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9777_RS13590	COG0539	negative regulation of cytoplasmic translation
D9777_RS13600	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D9777_RS13605	COG2959	enzyme of heme biosynthesis
D9777_RS13610	COG3773	Cell wall hydrolase
D9777_RS13610	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS13615	COG2339	peptidase activity
D9777_RS13620	COG0492	ferredoxin-NADP+ reductase activity
D9777_RS13625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9777_RS13630	COG4862	establishment of competence for transformation
D9777_RS13635	COG1408	metallophosphoesterase
D9777_RS13645	COG1388	LysM domain
D9777_RS13650	COG1266	CAAX protease self-immunity
D9777_RS13655	COG0514	ATP-dependent DNA helicase (RecQ)
D9777_RS13660	COG4955	Helix-turn-helix domain
D9777_RS13665	COG1141	Ferredoxin
D9777_RS13670	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9777_RS13675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9777_RS13685	COG1595	DNA-templated transcription, initiation
D9777_RS13690	COG5002	protein histidine kinase activity
D9777_RS13695	COG0745	RESPONSE REGULATOR receiver
D9777_RS13700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9777_RS13705	COG1333	cytochrome c biogenesis protein
D9777_RS13710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9777_RS13715	COG1187	pseudouridine synthase activity
D9777_RS13720	COG0700	Nucleoside recognition
D9777_RS13725	COG2715	membrane protein required for spore maturation
D9777_RS13730	COG1686	Belongs to the peptidase S11 family
D9777_RS13755	COG1547	Domain of unknown function (DUF309)
D9777_RS13765	COG0456	acetyltransferase
D9777_RS13780	COG0307	riboflavin synthase, alpha
D9777_RS13785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9777_RS13785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9777_RS13795	COG0681	Belongs to the peptidase S26 family
D9777_RS13805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9777_RS13810	COG4086	secreted protein
D9777_RS13815	COG0019	diaminopimelate decarboxylase activity
D9777_RS13820	COG0697	spore germination
D9777_RS13835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9777_RS13855	COG1191	sigma factor activity
D9777_RS13865	COG1366	Belongs to the anti-sigma-factor antagonist family
D9777_RS13870	COG1686	Belongs to the peptidase S11 family
D9777_RS13875	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D9777_RS13880	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9777_RS13885	COG4974	Belongs to the 'phage' integrase family
D9777_RS13895	COG0735	belongs to the Fur family
D9777_RS13900	COG1300	Membrane
D9777_RS13915	COG0281	malic enzyme
D9777_RS13920	COG1757	Na H antiporter
D9777_RS13925	COG1027	Aspartate ammonia-lyase
D9777_RS13930	COG0252	asparaginase activity
D9777_RS13935	COG1396	sequence-specific DNA binding
D9777_RS13940	COG1379	DNA repair
D9777_RS13945	COG0494	nUDIX hydrolase
D9777_RS13955	COG0667	Aldo Keto reductase
D9777_RS13965	COG1073	alpha beta
D9777_RS13975	COG4918	Iron-sulphur cluster biosynthesis
D9777_RS13980	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9777_RS13980	COG0456	acetyltransferase
D9777_RS13985	COG2329	Antibiotic biosynthesis monooxygenase
D9777_RS13990	COG0456	acetyltransferase
D9777_RS13995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9777_RS14020	COG0346	lactoylglutathione lyase activity
D9777_RS14030	COG3048	D-serine ammonia-lyase activity
D9777_RS14035	COG0300	oxidoreductase activity
D9777_RS14040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9777_RS14045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9777_RS14050	COG1024	Enoyl-CoA hydratase
D9777_RS14055	COG3425	synthase
D9777_RS14060	COG2124	cytochrome p450
D9777_RS14065	COG3321	synthase
D9777_RS14065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS14065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS14065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9777_RS14065	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS14070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS14070	COG3321	synthase
D9777_RS14070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9777_RS14070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS14070	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS14075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS14075	COG3321	synthase
D9777_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS14075	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS14075	COG0300	oxidoreductase activity
D9777_RS14080	COG3321	synthase
D9777_RS14080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS14080	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS14080	COG0300	oxidoreductase activity
D9777_RS14080	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS14085	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS14085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS14085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9777_RS14085	COG3321	synthase
D9777_RS14085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS14090	COG0300	oxidoreductase activity
D9777_RS14090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS14090	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS14090	COG3321	synthase
D9777_RS14095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9777_RS14095	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS14095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS14095	COG3321	synthase
D9777_RS14095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9777_RS14100	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS14105	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS14120	COG2070	2-Nitropropane dioxygenase
D9777_RS14120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9777_RS14125	COG0250	Participates in transcription elongation, termination and antitermination
D9777_RS14150	COG0596	Alpha beta hydrolase
D9777_RS14165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9777_RS14170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9777_RS14185	COG0706	membrane insertase activity
D9777_RS14190	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9777_RS14195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9777_RS14200	COG0346	lactoylglutathione lyase activity
D9777_RS14205	COG1376	ErfK ybiS ycfS ynhG family protein
D9777_RS14210	COG4129	membrane
D9777_RS14215	COG1126	abc transporter atp-binding protein
D9777_RS14220	COG0765	amino acid transport
D9777_RS14225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9777_RS14235	COG1597	lipid kinase activity
D9777_RS14240	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9777_RS14245	COG0022	dehydrogenase e1 component
D9777_RS14250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9777_RS14255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9777_RS14260	COG3426	butyrate kinase activity
D9777_RS14265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9777_RS14270	COG0280	phosphate acetyltransferase
D9777_RS14275	COG3829	transcription factor binding
D9777_RS14275	COG3290	protein histidine kinase activity
D9777_RS14285	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9777_RS14290	COG2079	MmgE PrpD family protein
D9777_RS14295	COG0372	Belongs to the citrate synthase family
D9777_RS14300	COG1960	acyl-CoA dehydrogenase activity
D9777_RS14305	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9777_RS14310	COG0183	Belongs to the thiolase family
D9777_RS14315	COG0584	glycerophosphoryl diester phosphodiesterase
D9777_RS14320	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9777_RS14340	COG1902	pentaerythritol trinitrate reductase activity
D9777_RS14355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9777_RS14360	COG0745	RESPONSE REGULATOR receiver
D9777_RS14365	COG0750	zinc metalloprotease
D9777_RS14370	COG0497	DNA recombination
D9777_RS14380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9777_RS14390	COG0142	geranyltranstransferase activity
D9777_RS14400	COG1570	exodeoxyribonuclease VII activity
D9777_RS14415	COG1302	Protein conserved in bacteria
D9777_RS14420	COG0439	Biotin carboxylase
D9777_RS14425	COG0511	ligase activity, forming carbon-carbon bonds
D9777_RS14465	COG3854	ATPases associated with a variety of cellular activities
D9777_RS14480	COG0006	proline dipeptidase activity
D9777_RS14490	COG3872	metal-dependent enzyme
D9777_RS14500	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9777_RS14515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9777_RS14535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9777_RS14550	COG1396	sequence-specific DNA binding
D9777_RS14560	COG0681	Belongs to the peptidase S26 family
D9777_RS14585	COG4940	Competence protein ComGF
D9777_RS14595	COG4970	Tfp pilus assembly protein FimT
D9777_RS14600	COG4537	Required for transformation and DNA binding
D9777_RS14605	COG1459	type II secretion system
D9777_RS14610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9777_RS14615	COG0598	Magnesium transport protein CorA
D9777_RS14620	COG1253	flavin adenine dinucleotide binding
D9777_RS14625	COG1366	Belongs to the anti-sigma-factor antagonist family
D9777_RS14635	COG1393	Belongs to the ArsC family
D9777_RS14645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9777_RS14655	COG0011	TIGRFAM Protein of
D9777_RS14665	COG2866	Carboxypeptidase
D9777_RS14670	COG1940	carbohydrate kinase activity
D9777_RS14675	COG4483	Protein conserved in bacteria
D9777_RS14680	COG1757	Na H antiporter
D9777_RS14690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9777_RS14705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9777_RS14710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9777_RS14715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9777_RS14720	COG0581	inorganic phosphate transmembrane transporter activity
D9777_RS14725	COG0573	inorganic phosphate transmembrane transporter activity
D9777_RS14730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9777_RS14735	COG0768	penicillin binding
D9777_RS14740	COG0477	Major facilitator Superfamily
D9777_RS14745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9777_RS14750	COG2839	Protein conserved in bacteria
D9777_RS14755	COG5521	maltodextrose utilization protein MalA
D9777_RS14760	COG1388	LysM domain
D9777_RS14770	COG4709	membrane
D9777_RS14775	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9777_RS14780	COG0735	belongs to the Fur family
D9777_RS14785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9777_RS14800	COG0513	Belongs to the DEAD box helicase family
D9777_RS14815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9777_RS14820	COG2384	SAM-dependent methyltransferase
D9777_RS14825	COG2010	Cytochrome c
D9777_RS14830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9777_RS14835	COG0358	DNA primase activity
D9777_RS14850	COG0517	IMP dehydrogenase activity
D9777_RS14855	COG0751	glycine-tRNA ligase activity
D9777_RS14875	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9777_RS14880	COG0295	cytidine deaminase activity
D9777_RS14885	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9777_RS14895	COG1480	7TM receptor with intracellular HD hydrolase
D9777_RS14900	COG1702	phosphate starvation-inducible protein PhoH
D9777_RS14905	COG0561	phosphatase activity
D9777_RS14920	COG4864	UPF0365 protein
D9777_RS14925	COG1030	water channel activity
D9777_RS14930	COG1610	YqeY-like protein
D9777_RS14940	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9777_RS14945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9777_RS14950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9777_RS14980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9777_RS14995	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9777_RS15010	COG1466	dna polymerase III delta subunit
D9777_RS15025	COG0658	competence protein
D9777_RS15025	COG2333	competence protein COMEC
D9777_RS15030	COG2131	deaminase
D9777_RS15035	COG1596	polysaccharide export
D9777_RS15035	COG1555	photosystem II stabilization
D9777_RS15040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9777_RS15045	COG2226	methyltransferase
D9777_RS15050	COG0799	negative regulation of ribosome biogenesis
D9777_RS15055	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9777_RS15065	COG1534	Rna-binding protein
D9777_RS15070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9777_RS15075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9777_RS15080	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9777_RS15090	COG2755	lipolytic protein G-D-S-L family
D9777_RS15100	COG0398	Pfam SNARE associated Golgi protein
D9777_RS15135	COG5444	nuclease activity
D9777_RS15140	COG4282	regulation of fungal-type cell wall biogenesis
D9777_RS15155	COG3708	Transcriptional regulator
D9777_RS15155	COG2207	Transcriptional regulator
D9777_RS15160	COG0583	DNA-binding transcription factor activity
D9777_RS15175	COG0642	Histidine kinase
D9777_RS15175	COG5002	protein histidine kinase activity
D9777_RS15180	COG0745	RESPONSE REGULATOR receiver
D9777_RS15185	COG2311	Membrane
D9777_RS15195	COG0454	-acetyltransferase
D9777_RS15210	COG2814	Major facilitator Superfamily
D9777_RS15230	COG5444	nuclease activity
D9777_RS15250	COG0456	acetyltransferase
D9777_RS15255	COG2318	DinB family
D9777_RS15265	COG0561	phosphatase activity
D9777_RS15270	COG0561	phosphatase activity
D9777_RS15280	COG1482	cell wall glycoprotein biosynthetic process
D9777_RS15285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9777_RS15285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9777_RS15285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9777_RS15290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9777_RS15290	COG3711	transcriptional antiterminator
D9777_RS15300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9777_RS15305	COG0583	DNA-binding transcription factor activity
D9777_RS15310	COG2814	Major facilitator Superfamily
D9777_RS15315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9777_RS15315	COG2124	cytochrome p450
D9777_RS15320	COG1309	transcriptional regulator
D9777_RS15325	COG2226	methyltransferase
D9777_RS15340	COG2116	formate transmembrane transporter activity
D9777_RS15345	COG5609	conserved protein (DUF2294)
D9777_RS15350	COG3383	formate dehydrogenase (NAD+) activity
D9777_RS15355	COG2427	Protein of unknown function (DUF1641)
D9777_RS15365	COG0626	cystathionine gamma-synthase activity
D9777_RS15370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9777_RS15395	COG0768	penicillin binding
D9777_RS15410	COG0826	peptidase U32
D9777_RS15415	COG0826	peptidase U32
D9777_RS15420	COG4122	O-methyltransferase activity
D9777_RS15425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9777_RS15440	COG4472	Bacterial protein of unknown function (DUF965)
D9777_RS15450	COG0628	permease
D9777_RS15455	COG1126	abc transporter atp-binding protein
D9777_RS15460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9777_RS15465	COG0765	amino acid transport
D9777_RS15470	COG0765	amino acid transport
D9777_RS15485	COG3881	PFAM PRC-barrel domain
D9777_RS15490	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9777_RS15495	COG0457	Tetratricopeptide repeat
D9777_RS15505	COG1104	cysteine desulfurase activity
D9777_RS15510	COG1959	2 iron, 2 sulfur cluster binding
D9777_RS15515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9777_RS15520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9777_RS15540	COG4991	sh3 domain protein
D9777_RS15540	COG3103	Sh3 type 3 domain protein
D9777_RS15540	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9777_RS15550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9777_RS15560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9777_RS15560	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9777_RS15565	COG5416	Lipopolysaccharide assembly protein A domain
D9777_RS15570	COG0490	domain, Protein
D9777_RS15575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9777_RS15575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9777_RS15585	COG2244	polysaccharide biosynthetic process
D9777_RS15590	COG2323	membrane
D9777_RS15600	COG1862	Preprotein translocase
D9777_RS15645	COG1388	LysM domain
D9777_RS15655	COG0157	Belongs to the NadC ModD family
D9777_RS15660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9777_RS15665	COG1104	cysteine desulfurase activity
D9777_RS15670	COG1827	regulation of RNA biosynthetic process
D9777_RS15675	COG0077	Prephenate dehydratase
D9777_RS15690	COG3290	protein histidine kinase activity
D9777_RS15695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9777_RS15700	COG2868	ribosomal protein
D9777_RS15710	COG1994	Peptidase M50
D9777_RS15715	COG0739	heme binding
D9777_RS15720	COG2894	cell division
D9777_RS15730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D9777_RS15740	COG1077	Cell shape determining protein MreB Mrl
D9777_RS15760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9777_RS15765	COG0285	dihydrofolate synthase activity
D9777_RS15770	COG0525	valine-tRNA ligase activity
D9777_RS15780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9777_RS15785	COG1388	LysM domain
D9777_RS15795	COG0113	porphobilinogen synthase activity
D9777_RS15800	COG1587	Uroporphyrinogen-III synthase
D9777_RS15810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9777_RS15830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9777_RS15835	COG0470	DNA polymerase III
D9777_RS15835	COG1067	ATP-dependent peptidase activity
D9777_RS15850	COG1477	protein flavinylation
D9777_RS15850	COG0457	Tetratricopeptide repeat
D9777_RS15865	COG0473	3-isopropylmalate dehydrogenase activity
D9777_RS15880	COG0440	acetolactate synthase activity
D9777_RS15910	COG0622	Phosphoesterase
D9777_RS15915	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9777_RS15925	COG5401	PFAM Sporulation and spore germination
D9777_RS15935	COG1846	Transcriptional regulator
D9777_RS15940	COG2197	response regulator
D9777_RS15945	COG0824	Thioesterase
D9777_RS15950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9777_RS15955	COG1053	succinate dehydrogenase
D9777_RS15960	COG2009	succinate dehydrogenase
D9777_RS15965	COG1719	4-vinyl reductase, 4VR
D9777_RS15970	COG0527	aspartate kinase activity
D9777_RS15985	COG3118	belongs to the thioredoxin family
D9777_RS15990	COG3534	alpha-L-arabinofuranosidase
D9777_RS15995	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9777_RS16000	COG2086	electron transfer activity
D9777_RS16005	COG1024	Enoyl-CoA hydratase
D9777_RS16010	COG1309	transcriptional regulator
D9777_RS16015	COG0318	PFAM AMP-dependent synthetase and ligase
D9777_RS16025	COG3766	membrane
D9777_RS16035	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9777_RS16035	COG1796	DNA polymerase
D9777_RS16040	COG1286	toxin biosynthetic process
D9777_RS16055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9777_RS16055	COG0072	phenylalanine-tRNA ligase activity
D9777_RS16060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9777_RS16065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9777_RS16075	COG3835	regulator
D9777_RS16080	COG0277	FAD linked oxidase domain protein
D9777_RS16085	COG0247	lactate metabolic process
D9777_RS16090	COG1966	Carbon starvation protein
D9777_RS16095	COG3534	alpha-L-arabinofuranosidase
D9777_RS16100	COG0395	ABC-type sugar transport system, permease component
D9777_RS16105	COG1175	transmembrane transport
D9777_RS16110	COG1653	transport
D9777_RS16120	COG0647	UMP catabolic process
D9777_RS16125	COG0235	Class ii aldolase
D9777_RS16130	COG1069	ribulokinase activity
D9777_RS16135	COG2160	L-arabinose isomerase activity
D9777_RS16140	COG3507	Belongs to the glycosyl hydrolase 43 family
D9777_RS16145	COG1363	Peptidase, m42
D9777_RS16155	COG3326	Membrane
D9777_RS16170	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9777_RS16175	COG1346	cytolysis
D9777_RS16180	COG1380	Effector of murein hydrolase LrgA
D9777_RS16185	COG3279	Response regulator of the LytR AlgR family
D9777_RS16190	COG3275	phosphorelay sensor kinase activity
D9777_RS16200	COG1011	Hydrolase
D9777_RS16215	COG0398	Pfam SNARE associated Golgi protein
D9777_RS16220	COG1484	DNA-dependent DNA replication
D9777_RS16225	COG3611	Membrane attachment protein
D9777_RS16240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9777_RS16245	COG1733	regulation of RNA biosynthetic process
D9777_RS16250	COG2814	Major facilitator Superfamily
D9777_RS16255	COG0656	L-ascorbic acid biosynthetic process
D9777_RS16260	COG0237	dephospho-CoA kinase activity
D9777_RS16265	COG1971	Probably functions as a manganese efflux pump
D9777_RS16270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9777_RS16275	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9777_RS16275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9777_RS16280	COG5002	protein histidine kinase activity
D9777_RS16285	COG0745	RESPONSE REGULATOR receiver
D9777_RS16295	COG0538	isocitrate dehydrogenase activity
D9777_RS16300	COG0372	Belongs to the citrate synthase family
D9777_RS16305	COG0457	Tetratricopeptide repeat
D9777_RS16335	COG0628	permease
D9777_RS16340	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9777_RS16345	COG0469	pyruvate kinase activity
D9777_RS16365	COG0281	malic enzyme
D9777_RS16370	COG0587	DNA-directed DNA polymerase activity
D9777_RS16390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9777_RS16400	COG4109	DRTGG domain
D9777_RS16410	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS16425	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9777_RS16435	COG0827	DNA restriction-modification system
D9777_RS16440	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9777_RS16445	COG3874	Sporulation protein YtfJ
D9777_RS16455	COG1714	RDD family
D9777_RS16460	COG0616	signal peptide processing
D9777_RS16465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9777_RS16470	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D9777_RS16475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9777_RS16490	COG1104	cysteine desulfurase activity
D9777_RS16495	COG1114	Component of the transport system for branched-chain amino acids
D9777_RS16505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9777_RS16510	COG1309	transcriptional regulator
D9777_RS16515	COG1956	GAF domain-containing protein
D9777_RS16535	COG1012	belongs to the aldehyde dehydrogenase family
D9777_RS16550	COG0305	Participates in initiation and elongation during chromosome replication
D9777_RS16555	COG1017	nitric oxide dioxygenase activity
D9777_RS16555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9777_RS16570	COG0693	protein deglycase activity
D9777_RS16585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9777_RS16590	COG1378	Sugar-specific transcriptional regulator TrmB
D9777_RS16615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9777_RS16620	COG0454	-acetyltransferase
D9777_RS16625	COG0517	IMP dehydrogenase activity
D9777_RS16630	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9777_RS16635	COG1360	Flagellar Motor Protein
D9777_RS16640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9777_RS16645	COG1609	Transcriptional regulator
D9777_RS16650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9777_RS16650	COG1605	Chorismate mutase
D9777_RS16655	COG3118	belongs to the thioredoxin family
D9777_RS16660	COG4980	gas vesicle protein
D9777_RS16665	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9777_RS16675	COG1674	ftsk spoiiie
D9777_RS16680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9777_RS16690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9777_RS16700	COG1363	Peptidase, m42
D9777_RS16705	COG5584	Small secreted protein
D9777_RS16710	COG0281	malic enzyme
D9777_RS16715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9777_RS16730	COG0510	thiamine kinase activity
D9777_RS16735	COG1597	lipid kinase activity
D9777_RS16745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9777_RS16750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9777_RS16755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9777_RS16760	COG2252	PERMEase
D9777_RS16765	COG4473	ABC transporter
D9777_RS16770	COG1131	(ABC) transporter
D9777_RS16775	COG1349	DNA-binding transcription factor activity
D9777_RS16780	COG1187	pseudouridine synthase activity
D9777_RS16785	COG2244	polysaccharide biosynthetic process
D9777_RS16790	COG2081	HI0933 family
D9777_RS16795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9777_RS16805	COG1609	Transcriptional regulator
D9777_RS16810	COG1653	transport
D9777_RS16815	COG1175	transmembrane transport
D9777_RS16820	COG0395	ABC-type sugar transport system, permease component
D9777_RS16825	COG1486	melibiose metabolic process
D9777_RS16835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9777_RS16850	COG1366	Belongs to the anti-sigma-factor antagonist family
D9777_RS16850	COG2202	Pas domain
D9777_RS16855	COG2814	Major facilitator Superfamily
D9777_RS16860	COG5522	Integral membrane protein (intg_mem_TP0381)
D9777_RS16865	COG0577	efflux transmembrane transporter activity
D9777_RS16870	COG1136	(ABC) transporter
D9777_RS16875	COG2205	protein histidine kinase activity
D9777_RS16880	COG0745	RESPONSE REGULATOR receiver
D9777_RS16885	COG0577	efflux transmembrane transporter activity
D9777_RS16890	COG1136	(ABC) transporter
D9777_RS16910	COG1131	(ABC) transporter
D9777_RS16915	COG1725	Transcriptional regulator
D9777_RS16925	COG1242	4 iron, 4 sulfur cluster binding
D9777_RS16930	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9777_RS16940	COG0584	glycerophosphoryl diester phosphodiesterase
D9777_RS16950	COG2267	carboxylic ester hydrolase activity
D9777_RS16955	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9777_RS16960	COG1113	amino acid transport
D9777_RS16965	COG0367	asparagine synthase
D9777_RS16985	COG1506	peptidase
D9777_RS16990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9777_RS16995	COG1116	anion transmembrane transporter activity
D9777_RS17000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9777_RS17005	COG0494	nUDIX hydrolase
D9777_RS17010	COG4824	toxin secretion phage lysis holin
D9777_RS17015	COG0783	Belongs to the Dps family
D9777_RS17040	COG0288	reversible hydration of carbon dioxide
D9777_RS17050	COG1271	oxidase subunit
D9777_RS17055	COG1294	oxidase, subunit
D9777_RS17065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9777_RS17070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9777_RS17070	COG1321	iron dependent repressor
D9777_RS17075	COG1121	(ABC) transporter
D9777_RS17080	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9777_RS17085	COG4948	Mandelate Racemase Muconate Lactonizing
D9777_RS17095	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9777_RS17100	COG0596	Alpha beta hydrolase
D9777_RS17110	COG1169	isochorismate synthase
D9777_RS17115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9777_RS17120	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D9777_RS17250	COG3859	Proton-coupled thiamine transporter YuaJ
D9777_RS17255	COG2268	Band 7 protein
D9777_RS17260	COG1585	Membrane protein implicated in regulation of membrane protease activity
D9777_RS17265	COG2318	DinB family
D9777_RS17275	COG1454	alcohol dehydrogenase
D9777_RS17280	COG1012	belongs to the aldehyde dehydrogenase family
D9777_RS17285	COG1510	regulation of RNA biosynthetic process
D9777_RS17295	COG0569	domain protein
D9777_RS17300	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9777_RS17305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9777_RS17305	COG1017	nitric oxide dioxygenase activity
D9777_RS17330	COG0628	permease
D9777_RS17335	COG0673	inositol 2-dehydrogenase activity
D9777_RS17340	COG0693	protein deglycase activity
D9777_RS17345	COG0840	transmembrane signaling receptor activity
D9777_RS17350	COG0840	transmembrane signaling receptor activity
D9777_RS17355	COG0840	transmembrane signaling receptor activity
D9777_RS17360	COG0840	transmembrane signaling receptor activity
D9777_RS17375	COG2070	2-Nitropropane dioxygenase
D9777_RS17380	COG0432	Pfam Uncharacterised protein family UPF0047
D9777_RS17385	COG0366	Alpha amylase catalytic
D9777_RS17390	COG1253	flavin adenine dinucleotide binding
D9777_RS17395	COG2738	Putative neutral zinc metallopeptidase
D9777_RS17410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9777_RS17440	COG1335	isochorismatase
D9777_RS17445	COG1979	alcohol dehydrogenase
D9777_RS17450	COG1979	alcohol dehydrogenase
D9777_RS17455	COG2155	Conserved Protein
D9777_RS17460	COG1098	S1 RNA binding domain
D9777_RS17465	COG0436	Aminotransferase
D9777_RS17470	COG1522	sequence-specific DNA binding
D9777_RS17475	COG2267	carboxylic ester hydrolase activity
D9777_RS17485	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9777_RS17490	COG2205	protein histidine kinase activity
D9777_RS17500	COG5018	Exonuclease
D9777_RS17505	COG2814	Major facilitator Superfamily
D9777_RS17510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9777_RS17515	COG3011	Protein conserved in bacteria
D9777_RS17525	COG3290	protein histidine kinase activity
D9777_RS17530	COG4565	transcriptional regulatory protein
D9777_RS17535	COG1744	ABC transporter substrate-binding protein PnrA-like
D9777_RS17540	COG3845	ABC transporter
D9777_RS17545	COG4603	Belongs to the binding-protein-dependent transport system permease family
D9777_RS17550	COG1079	Belongs to the binding-protein-dependent transport system permease family
D9777_RS17560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9777_RS17560	COG2111	Na H antiporter
D9777_RS17565	COG2111	Na H antiporter
D9777_RS17570	COG1006	Multisubunit Na H antiporter MnhC subunit
D9777_RS17575	COG0651	ATP synthesis coupled electron transport
D9777_RS17580	COG1863	multisubunit Na H antiporter MnhE subunit
D9777_RS17585	COG2212	antiporter activity
D9777_RS17590	COG1320	monovalent cation:proton antiporter activity
D9777_RS17595	COG2050	protein possibly involved in aromatic compounds catabolism
D9777_RS17600	COG2197	response regulator
D9777_RS17605	COG4585	Histidine kinase
D9777_RS17615	COG0142	geranyltranstransferase activity
D9777_RS17635	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D9777_RS17640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9777_RS17645	COG1335	isochorismatase
D9777_RS17650	COG5506	Protein of unknown function (DUF1694)
D9777_RS17665	COG0628	permease
D9777_RS17675	COG1418	mRNA catabolic process
D9777_RS17680	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS17695	COG0433	COG0433 Predicted ATPase
D9777_RS17695	COG1674	ftsk spoiiie
D9777_RS17705	COG5417	Belongs to the EsaB family
D9777_RS17710	COG4842	Belongs to the WXG100 family
D9777_RS17715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9777_RS17715	COG2508	Transcriptional regulator
D9777_RS17720	COG0686	Belongs to the AlaDH PNT family
D9777_RS17725	COG5634	Uncharacterized conserved protein (DUF2278)
D9777_RS17730	COG3251	PFAM MbtH domain protein
D9777_RS17735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9777_RS17740	COG1535	isochorismatase
D9777_RS17740	COG3433	isochorismatase activity
D9777_RS17745	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9777_RS17750	COG1169	isochorismate synthase
D9777_RS17755	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS17760	COG2819	hydrolase of the alpha beta superfamily
D9777_RS17765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9777_RS17770	COG1268	BioY protein
D9777_RS17775	COG2056	Na+-H+ antiporter family
D9777_RS17785	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9777_RS17790	COG3584	3D domain protein
D9777_RS17805	COG1252	NADH dehydrogenase
D9777_RS17835	COG1131	(ABC) transporter
D9777_RS17855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9777_RS17860	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D9777_RS17865	COG0316	Belongs to the HesB IscA family
D9777_RS17875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9777_RS17885	COG1252	NADH dehydrogenase
D9777_RS17890	COG4837	Protein of unknown function (DUF1462)
D9777_RS17895	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9777_RS17900	COG4946	Tricorn protease homolog
D9777_RS17900	COG1506	peptidase
D9777_RS17900	COG0823	Involved in the tonB-independent uptake of proteins
D9777_RS17910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9777_RS17915	COG0460	homoserine dehydrogenase
D9777_RS17920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9777_RS17925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9777_RS17930	COG0647	UMP catabolic process
D9777_RS17935	COG2445	Protein of unknown function DUF86
D9777_RS17940	COG4470	Protein conserved in bacteria
D9777_RS17955	COG0739	heme binding
D9777_RS17965	COG0737	Belongs to the 5'-nucleotidase family
D9777_RS17970	COG0730	response to heat
D9777_RS17975	COG1801	Protein of unknown function DUF72
D9777_RS17990	COG2508	Transcriptional regulator
D9777_RS17995	COG0457	Tetratricopeptide repeat
D9777_RS18010	COG2814	Major facilitator Superfamily
D9777_RS18015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D9777_RS18020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9777_RS18025	COG2356	endonuclease I
D9777_RS18030	COG3842	ATPase activity
D9777_RS18035	COG2188	Transcriptional regulator
D9777_RS18040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9777_RS18045	COG0395	ABC-type sugar transport system, permease component
D9777_RS18050	COG1175	transmembrane transport
D9777_RS18055	COG1653	transport
D9777_RS18060	COG2222	sugar isomerase
D9777_RS18065	COG0789	Transcriptional regulator
D9777_RS18090	COG0322	excinuclease ABC activity
D9777_RS18095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9777_RS18120	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS18125	COG0719	Fe-S assembly protein
D9777_RS18130	COG0822	iron-sulfur transferase activity
D9777_RS18135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9777_RS18140	COG0719	Fe-S assembly protein
D9777_RS18145	COG0396	ATPase activity
D9777_RS18155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9777_RS18160	COG1464	Belongs to the NlpA lipoprotein family
D9777_RS18165	COG2011	ABC-type metal ion transport system permease component
D9777_RS18170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9777_RS18180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9777_RS18185	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9777_RS18200	COG1393	Belongs to the ArsC family
D9777_RS18205	COG1960	acyl-CoA dehydrogenase activity
D9777_RS18210	COG0183	Belongs to the thiolase family
D9777_RS18215	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9777_RS18215	COG1024	Enoyl-CoA hydratase
D9777_RS18235	COG5577	PFAM Coat F domain
D9777_RS18240	COG1846	Transcriptional regulator
D9777_RS18245	COG0477	Major facilitator Superfamily
D9777_RS18250	COG0583	DNA-binding transcription factor activity
D9777_RS18270	COG1120	ATPase activity
D9777_RS18285	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS18290	COG0783	Belongs to the Dps family
D9777_RS18295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9777_RS18300	COG0745	RESPONSE REGULATOR receiver
D9777_RS18305	COG2770	Histidine kinase
D9777_RS18305	COG2205	protein histidine kinase activity
D9777_RS18315	COG1309	transcriptional regulator
D9777_RS18320	COG0114	fumarate hydratase activity
D9777_RS18330	COG0697	spore germination
D9777_RS18335	COG0814	amino acid
D9777_RS18345	COG2197	response regulator
D9777_RS18350	COG4585	Histidine kinase
D9777_RS18355	COG4758	membrane
D9777_RS18360	COG3595	metallopeptidase activity
D9777_RS18365	COG1842	Phage shock protein A
D9777_RS18370	COG4758	membrane
D9777_RS18375	COG2814	Major facilitator Superfamily
D9777_RS18380	COG2096	Adenosyltransferase
D9777_RS18385	COG1120	ATPase activity
D9777_RS18390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9777_RS18395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9777_RS18400	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS18405	COG3386	PFAM SMP-30 Gluconolaconase
D9777_RS18410	COG2205	protein histidine kinase activity
D9777_RS18415	COG0745	RESPONSE REGULATOR receiver
D9777_RS18425	COG1191	sigma factor activity
D9777_RS18435	COG2140	Oxalate decarboxylase
D9777_RS18450	COG1120	ATPase activity
D9777_RS18455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9777_RS18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9777_RS18465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9777_RS18470	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9777_RS18475	COG0531	amino acid
D9777_RS18490	COG1988	membrane-bound metal-dependent
D9777_RS18495	COG1368	sulfuric ester hydrolase activity
D9777_RS18500	COG1910	domain protein
D9777_RS18505	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9777_RS18510	COG4149	molybdate abc transporter
D9777_RS18515	COG2197	response regulator
D9777_RS18520	COG3850	Histidine kinase
D9777_RS18525	COG1131	(ABC) transporter
D9777_RS18535	COG0842	Transport permease protein
D9777_RS18540	COG0656	L-ascorbic acid biosynthetic process
D9777_RS18565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9777_RS18570	COG3973	AAA domain
D9777_RS18575	COG2860	membrane
D9777_RS18585	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9777_RS18590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D9777_RS18595	COG2217	Heavy metal translocating P-type atpase
D9777_RS18600	COG2217	Heavy metal translocating P-type atpase
D9777_RS18605	COG2608	mercury ion transmembrane transporter activity
D9777_RS18610	COG1937	Protein conserved in bacteria
D9777_RS18615	COG0673	inositol 2-dehydrogenase activity
D9777_RS18625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9777_RS18630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D9777_RS18635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9777_RS18640	COG1126	abc transporter atp-binding protein
D9777_RS18645	COG0765	amino acid transport
D9777_RS18650	COG0765	amino acid transport
D9777_RS18655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9777_RS18660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9777_RS18665	COG0454	-acetyltransferase
D9777_RS18670	COG0583	DNA-binding transcription factor activity
D9777_RS18675	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS18680	COG2732	(Barnase) inhibitor
D9777_RS18695	COG0557	exoribonuclease II activity
D9777_RS18700	COG1647	Serine aminopeptidase, S33
D9777_RS18705	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9777_RS18710	COG1476	TRANSCRIPTIONal
D9777_RS18715	COG1396	sequence-specific DNA binding
D9777_RS18720	COG1396	sequence-specific DNA binding
D9777_RS18725	COG1733	regulation of RNA biosynthetic process
D9777_RS18750	COG1131	(ABC) transporter
D9777_RS18755	COG1174	glycine betaine transport
D9777_RS18760	COG1732	Glycine betaine
D9777_RS18765	COG1174	glycine betaine transport
D9777_RS18770	COG0517	IMP dehydrogenase activity
D9777_RS18770	COG1125	glycine betaine transport
D9777_RS18775	COG1510	regulation of RNA biosynthetic process
D9777_RS18780	COG1174	glycine betaine transport
D9777_RS18785	COG1732	Glycine betaine
D9777_RS18790	COG1174	glycine betaine transport
D9777_RS18795	COG0517	IMP dehydrogenase activity
D9777_RS18795	COG1125	glycine betaine transport
D9777_RS18800	COG1510	regulation of RNA biosynthetic process
D9777_RS18805	COG2095	MarC family integral membrane protein
D9777_RS18815	COG3064	Membrane
D9777_RS18820	COG4640	response to antibiotic
D9777_RS18825	COG0456	acetyltransferase
D9777_RS18875	COG0126	phosphoglycerate kinase activity
D9777_RS18885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9777_RS18890	COG2390	Transcriptional regulator
D9777_RS18895	COG2814	Major facilitator Superfamily
D9777_RS18900	COG1609	Transcriptional regulator
D9777_RS18910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9777_RS18915	COG0583	DNA-binding transcription factor activity
D9777_RS18920	COG0697	spore germination
D9777_RS18925	COG1113	amino acid transport
D9777_RS18930	COG1737	Transcriptional regulator
D9777_RS18935	COG1070	Carbohydrate kinase
D9777_RS18960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9777_RS18965	COG2186	Transcriptional regulator
D9777_RS18970	COG1620	l-lactate permease
D9777_RS18975	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9777_RS18985	COG5039	Polysaccharide pyruvyl transferase
D9777_RS18990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9777_RS18995	COG0110	maltose O-acetyltransferase activity
D9777_RS19000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9777_RS19005	COG2244	polysaccharide biosynthetic process
D9777_RS19010	COG1216	Glycosyl transferase, family 2
D9777_RS19015	COG5039	Polysaccharide pyruvyl transferase
D9777_RS19020	COG1216	Glycosyl transferase, family 2
D9777_RS19030	COG0438	transferase activity, transferring glycosyl groups
D9777_RS19035	COG1215	transferase activity, transferring glycosyl groups
D9777_RS19040	COG0438	transferase activity, transferring glycosyl groups
D9777_RS19045	COG1086	Polysaccharide biosynthesis protein
D9777_RS19050	COG0489	protein tyrosine kinase activity
D9777_RS19055	COG3944	biosynthesis protein
D9777_RS19060	COG1396	sequence-specific DNA binding
D9777_RS19065	COG2272	Belongs to the type-B carboxylesterase lipase family
D9777_RS19075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9777_RS19080	COG2364	Membrane
D9777_RS19085	COG0456	acetyltransferase
D9777_RS19090	COG3479	Phenolic acid decarboxylase
D9777_RS19130	COG2223	nitrite transmembrane transporter activity
D9777_RS19135	COG1609	Transcriptional regulator
D9777_RS19145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9777_RS19150	COG0366	Alpha amylase catalytic
D9777_RS19155	COG1554	hydrolase, family 65, central catalytic
D9777_RS19160	COG5521	maltodextrose utilization protein MalA
D9777_RS19165	COG3833	ABC-type maltose transport systems, permease component
D9777_RS19170	COG1175	transmembrane transport
D9777_RS19175	COG2182	Extracellular solute-binding protein
D9777_RS19180	COG0366	Alpha amylase catalytic
D9777_RS19185	COG1609	Transcriptional regulator
D9777_RS19190	COG1611	Belongs to the LOG family
D9777_RS19195	COG1694	Mazg nucleotide pyrophosphohydrolase
D9777_RS19200	COG0659	secondary active sulfate transmembrane transporter activity
D9777_RS19205	COG0288	reversible hydration of carbon dioxide
D9777_RS19215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9777_RS19220	COG4290	ribonuclease
D9777_RS19225	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D9777_RS19230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9777_RS19240	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9777_RS19250	COG1051	belongs to the nudix hydrolase family
D9777_RS19255	COG0492	ferredoxin-NADP+ reductase activity
D9777_RS19260	COG3883	PFAM NLP P60 protein
D9777_RS19260	COG0791	NLP P60 protein
D9777_RS19265	COG0457	Tetratricopeptide repeat
D9777_RS19270	COG5002	protein histidine kinase activity
D9777_RS19275	COG0745	RESPONSE REGULATOR receiver
D9777_RS19285	COG1132	(ABC) transporter
D9777_RS19290	COG0140	phosphoribosyl-ATP diphosphatase activity
D9777_RS19290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9777_RS19315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9777_RS19330	COG4990	cell redox homeostasis
D9777_RS19335	COG0110	maltose O-acetyltransferase activity
D9777_RS19355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9777_RS19365	COG2188	Transcriptional regulator
D9777_RS19370	COG1309	transcriptional regulator
D9777_RS19375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9777_RS19380	COG1950	PFAM Membrane protein of
D9777_RS19385	COG1983	PspC domain protein
D9777_RS19390	COG3595	metallopeptidase activity
D9777_RS19405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9777_RS19415	COG4897	Protein conserved in bacteria
D9777_RS19420	COG0574	Belongs to the PEP-utilizing enzyme family
D9777_RS19420	COG3848	Pyruvate phosphate dikinase
D9777_RS19425	COG1309	transcriptional regulator
D9777_RS19430	COG2814	Major facilitator Superfamily
D9777_RS19465	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS19480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9777_RS19490	COG3409	Peptidoglycan-binding domain 1 protein
D9777_RS19490	COG0793	Belongs to the peptidase S41A family
D9777_RS19495	COG3420	alginic acid biosynthetic process
D9777_RS19500	COG2177	Part of the ABC transporter FtsEX involved in
D9777_RS19505	COG2884	Cell division ATP-binding protein ftsE
D9777_RS19510	COG2010	Cytochrome c
D9777_RS19515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9777_RS19530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D9777_RS19545	COG1516	flagellar protein fliS
D9777_RS19550	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9777_RS19555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9777_RS19575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9777_RS19580	COG4786	Flagellar basal body rod
D9777_RS19580	COG1256	bacterial-type flagellum assembly
D9777_RS19585	COG3418	PFAM FlgN family protein
D9777_RS19590	COG2747	anti-sigma28 factor FlgM
D9777_RS19600	COG1040	competence protein
D9777_RS19615	COG1307	EDD domain protein, DegV family
D9777_RS19620	COG2197	response regulator
D9777_RS19625	COG4585	Histidine kinase
D9777_RS19630	COG1739	Uncharacterized protein family UPF0029
D9777_RS19635	COG1316	TRANSCRIPTIONal
D9777_RS19640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9777_RS19645	COG0438	transferase activity, transferring glycosyl groups
D9777_RS19650	COG1215	transferase activity, transferring glycosyl groups
D9777_RS19655	COG3206	protein involved in exopolysaccharide biosynthesis
D9777_RS19660	COG3307	-O-antigen
D9777_RS19665	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9777_RS19670	COG0438	transferase activity, transferring glycosyl groups
D9777_RS19670	COG0297	glycogen (starch) synthase activity
D9777_RS19675	COG2244	polysaccharide biosynthetic process
D9777_RS19685	COG2247	cell wall binding repeat
D9777_RS19685	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9777_RS19690	COG2247	cell wall binding repeat
D9777_RS19690	COG2385	sporulation resulting in formation of a cellular spore
D9777_RS19700	COG1316	TRANSCRIPTIONal
D9777_RS19705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9777_RS19710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9777_RS19715	COG1134	teichoic acid transport
D9777_RS19720	COG1682	transport, permease protein
D9777_RS19730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9777_RS19735	COG0438	transferase activity, transferring glycosyl groups
D9777_RS19740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9777_RS19745	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D9777_RS19750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9777_RS19755	COG4193	domain, Protein
D9777_RS19760	COG1482	cell wall glycoprotein biosynthetic process
D9777_RS19765	COG0697	spore germination
D9777_RS19770	COG0814	amino acid
D9777_RS19780	COG1215	transferase activity, transferring glycosyl groups
D9777_RS19785	COG2814	Major facilitator Superfamily
D9777_RS19790	COG1316	TRANSCRIPTIONal
D9777_RS19795	COG0561	phosphatase activity
D9777_RS19800	COG2433	Pfam Transposase IS66
D9777_RS19805	COG0791	NLP P60 protein
D9777_RS19815	COG2843	Capsule synthesis protein
D9777_RS19825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9777_RS19835	COG0697	spore germination
D9777_RS19840	COG0814	amino acid
D9777_RS19850	COG1609	Transcriptional regulator
D9777_RS19855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9777_RS19865	COG1129	ABC transporter
D9777_RS19870	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9777_RS19875	COG1879	ABC-type sugar transport system periplasmic component
D9777_RS19880	COG3103	Sh3 type 3 domain protein
D9777_RS19885	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9777_RS19890	COG3527	Alpha-acetolactate decarboxylase
D9777_RS19895	COG0028	Belongs to the TPP enzyme family
D9777_RS19900	COG0583	DNA-binding transcription factor activity
D9777_RS19905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9777_RS19920	COG5337	Spore coat protein CotH
D9777_RS19930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9777_RS19940	COG0405	Gamma-glutamyltransferase
D9777_RS19945	COG1522	sequence-specific DNA binding
D9777_RS19950	COG2059	Chromate
D9777_RS19955	COG2059	Chromate
D9777_RS19965	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9777_RS19970	COG0583	DNA-binding transcription factor activity
D9777_RS19995	COG5444	nuclease activity
D9777_RS20010	COG3878	Protein conserved in bacteria
D9777_RS20015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9777_RS20020	COG4464	protein tyrosine phosphatase activity
D9777_RS20025	COG0489	protein tyrosine kinase activity
D9777_RS20030	COG3944	biosynthesis protein
D9777_RS20045	COG4715	Zinc finger, swim domain protein
D9777_RS20050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9777_RS20055	COG0561	phosphatase activity
D9777_RS20060	COG1349	DNA-binding transcription factor activity
D9777_RS20065	COG0629	single-stranded DNA binding
D9777_RS20090	COG0457	Tetratricopeptide repeat
D9777_RS20095	COG4786	Flagellar basal body rod
D9777_RS20100	COG4786	Flagellar basal body rod
D9777_RS20105	COG1077	Cell shape determining protein MreB Mrl
D9777_RS20110	COG1609	Transcriptional regulator
D9777_RS20115	COG1846	Transcriptional regulator
D9777_RS20120	COG2814	Major facilitator Superfamily
D9777_RS20125	COG1953	Uracil, thiamine, allantoin
D9777_RS20130	COG0477	Major facilitator Superfamily
D9777_RS20135	COG1335	isochorismatase
D9777_RS20140	COG0004	ammonium transporteR
D9777_RS20145	COG0347	Belongs to the P(II) protein family
D9777_RS20150	COG0772	Belongs to the SEDS family
D9777_RS20155	COG0671	phosphoesterase, PA-phosphatase related
D9777_RS20165	COG0739	heme binding
D9777_RS20170	COG1247	-acetyltransferase
D9777_RS20185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9777_RS20195	COG0726	polysaccharide deacetylase
D9777_RS20205	COG1959	2 iron, 2 sulfur cluster binding
D9777_RS20220	COG0831	urea catabolic process
D9777_RS20230	COG1994	Peptidase M50
D9777_RS20235	COG0457	Tetratricopeptide repeat
D9777_RS20245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9777_RS20250	COG2304	oxidoreductase activity
D9777_RS20255	COG2304	oxidoreductase activity
D9777_RS20265	COG2385	sporulation resulting in formation of a cellular spore
D9777_RS20270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9777_RS20280	COG4836	Membrane
D9777_RS20350	COG0698	ribose 5-phosphate isomerase
D9777_RS20355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9777_RS20365	COG0009	L-threonylcarbamoyladenylate synthase
D9777_RS20370	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D9777_RS20390	COG2890	protein-(glutamine-N5) methyltransferase activity
D9777_RS20395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9777_RS20400	COG0346	lactoylglutathione lyase activity
D9777_RS20405	COG0789	Transcriptional regulator
D9777_RS20410	COG0679	Auxin Efflux Carrier
D9777_RS20415	COG0281	malic enzyme
D9777_RS20430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9777_RS20435	COG1494	fructose-1,6-bisphosphatase
D9777_RS20440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9777_RS20450	COG0191	fructose-bisphosphate aldolase activity
D9777_RS20455	COG2204	response regulator
D9777_RS20460	COG4821	SIS domain
D9777_RS20475	COG2181	nitrate reductase activity
D9777_RS20475	COG0247	lactate metabolic process
D9777_RS20480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9777_RS20495	COG1132	(ABC) transporter
D9777_RS20500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9777_RS20510	COG2181	nitrate reductase activity
D9777_RS20515	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D9777_RS20520	COG1140	nitrate reductase beta subunit
D9777_RS20525	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D9777_RS20530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9777_RS20540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9777_RS20545	COG2223	nitrite transmembrane transporter activity
D9777_RS20555	COG4506	Protein conserved in bacteria
D9777_RS20560	COG0457	Tetratricopeptide repeat
D9777_RS20605	COG0010	Belongs to the arginase family
D9777_RS20610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9777_RS20615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9777_RS20630	COG1994	Peptidase M50
D9777_RS20635	COG1942	4-Oxalocrotonate Tautomerase
D9777_RS20640	COG1846	Transcriptional regulator
D9777_RS20650	COG0531	amino acid
D9777_RS20655	COG3465	dGTPase activity
D9777_RS20660	COG1078	dGTPase activity
D9777_RS20675	COG1695	Transcriptional regulator
D9777_RS20685	COG1131	(ABC) transporter
D9777_RS20690	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9777_RS20720	COG0583	DNA-binding transcription factor activity
D9777_RS20725	COG2855	membrane
D9777_RS20730	COG0280	phosphate acetyltransferase
D9777_RS20740	COG1028	Short-chain dehydrogenase reductase Sdr
D9777_RS20745	COG0436	Aminotransferase
D9777_RS20780	COG2814	Major facilitator Superfamily
D9777_RS20785	COG0833	amino acid
D9777_RS20790	COG4187	Peptidase family M20/M25/M40
D9777_RS20795	COG1012	belongs to the aldehyde dehydrogenase family
D9777_RS20800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9777_RS20805	COG2205	protein histidine kinase activity
D9777_RS20810	COG0745	RESPONSE REGULATOR receiver
D9777_RS20825	COG1131	(ABC) transporter
D9777_RS20830	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D9777_RS20835	COG1091	dTDP-4-dehydrorhamnose reductase activity
D9777_RS20840	COG1088	dTDP-glucose 4,6-dehydratase activity
D9777_RS20845	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D9777_RS20850	COG3980	spore coat polysaccharide biosynthesis protein
D9777_RS20855	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D9777_RS20860	COG2089	acid synthase
D9777_RS20865	COG0456	acetyltransferase
D9777_RS20870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9777_RS20875	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9777_RS20880	COG0463	Glycosyl transferase, family 2
D9777_RS20890	COG2363	Small membrane protein
D9777_RS20895	COG2233	PERMEase
D9777_RS20910	COG1216	Glycosyl transferase, family 2
D9777_RS20925	COG1695	Transcriptional regulator
D9777_RS20930	COG0351	phosphomethylpyrimidine kinase
D9777_RS20940	COG1621	beta-fructofuranosidase activity
D9777_RS20945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9777_RS20945	COG1263	PTS System
D9777_RS20950	COG3711	transcriptional antiterminator
D9777_RS20960	COG1404	Belongs to the peptidase S8 family
D9777_RS20965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9777_RS20970	COG0778	Nitroreductase
D9777_RS20975	COG1136	(ABC) transporter
D9777_RS20995	COG0772	Belongs to the SEDS family
D9777_RS21000	COG0454	-acetyltransferase
D9777_RS21020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9777_RS21025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9777_RS21030	COG2261	transglycosylase associated protein
D9777_RS21035	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9777_RS21040	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9777_RS21045	COG2246	polysaccharide biosynthetic process
D9777_RS21050	COG1309	transcriptional regulator
D9777_RS21070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9777_RS21075	COG2837	iron assimilation
D9777_RS21080	COG2822	iron ion transport
D9777_RS21095	COG0583	DNA-binding transcription factor activity
D9777_RS21105	COG1346	cytolysis
D9777_RS21110	COG4895	conserved protein (DUF2196)
D9777_RS21115	COG0789	Transcriptional regulator
D9777_RS21120	COG5504	Zn-dependent protease
D9777_RS21125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9777_RS21130	COG0346	lactoylglutathione lyase activity
D9777_RS21135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9777_RS21140	COG1404	Belongs to the peptidase S8 family
D9777_RS21145	COG1442	glycosyl transferase family 8
D9777_RS21150	COG1846	Transcriptional regulator
D9777_RS21155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9777_RS21160	COG2357	RelA SpoT domain protein
D9777_RS21165	COG1575	Belongs to the MenA family. Type 1 subfamily
D9777_RS21185	COG1696	Membrane protein involved in D-alanine export
D9777_RS21195	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D9777_RS21200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9777_RS21205	COG1486	melibiose metabolic process
D9777_RS21210	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9777_RS21215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9777_RS21220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9777_RS21225	COG3711	transcriptional antiterminator
D9777_RS21225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9777_RS21240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9777_RS21245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9777_RS21255	COG0640	Transcriptional regulator
D9777_RS21260	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9777_RS21265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9777_RS21270	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9777_RS21275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9777_RS21280	COG2723	6-phospho-beta-galactosidase activity
D9777_RS21285	COG1940	carbohydrate kinase activity
D9777_RS21290	COG1482	cell wall glycoprotein biosynthetic process
D9777_RS21300	COG0753	catalase activity
D9777_RS21305	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D9777_RS21310	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9777_RS21315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
