locus-tag	class	description
KK132_RS00010	COG0592	DNA-directed DNA polymerase activity
KK132_RS00015	COG2501	S4 domain
KK132_RS00030	COG0187	DNA topoisomerase II activity
KK132_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KK132_RS00070	COG0516	GMP reductase activity
KK132_RS00070	COG0517	IMP dehydrogenase activity
KK132_RS00075	COG1686	Belongs to the peptidase S11 family
KK132_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
KK132_RS00105	COG1428	Deoxynucleoside kinase
KK132_RS00110	COG1428	Deoxynucleoside kinase
KK132_RS00115	COG1388	LysM domain
KK132_RS00115	COG3858	chitin binding
KK132_RS00120	COG1335	isochorismatase
KK132_RS00125	COG0590	tRNA wobble adenosine to inosine editing
KK132_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KK132_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KK132_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KK132_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KK132_RS00195	COG3853	Toxic anion resistance protein (TelA)
KK132_RS00200	COG1982	Orn Lys Arg decarboxylase major
KK132_RS00210	COG3870	Protein conserved in bacteria
KK132_RS00215	COG1728	Protein conserved in bacteria
KK132_RS00220	COG0470	DNA polymerase III
KK132_RS00225	COG1774	PSP1 C-terminal conserved region
KK132_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KK132_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KK132_RS00250	COG2002	toxin-antitoxin pair type II binding
KK132_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KK132_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KK132_RS00260	COG0084	hydrolase, TatD family'
KK132_RS00265	COG3584	3D domain protein
KK132_RS00265	COG3583	domain protein
KK132_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KK132_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KK132_RS00285	COG4466	Protein conserved in bacteria
KK132_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KK132_RS00305	COG0251	oxidation-reduction process
KK132_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KK132_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KK132_RS00345	COG2002	toxin-antitoxin pair type II binding
KK132_RS00350	COG2244	polysaccharide biosynthetic process
KK132_RS00355	COG3956	TIGRFAM MazG family protein
KK132_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KK132_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KK132_RS00380	COG1098	S1 RNA binding domain
KK132_RS00395	COG2208	phosphoserine phosphatase activity
KK132_RS00400	COG2304	oxidoreductase activity
KK132_RS00405	COG0515	serine threonine protein kinase
KK132_RS00410	COG0037	tRNA processing
KK132_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KK132_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KK132_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KK132_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KK132_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KK132_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
KK132_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KK132_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KK132_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KK132_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KK132_RS00475	COG1396	sequence-specific DNA binding
KK132_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KK132_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KK132_RS00565	COG4463	regulation of RNA biosynthetic process
KK132_RS00570	COG3880	PFAM UvrB UvrC protein
KK132_RS00580	COG0542	response to heat
KK132_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KK132_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KK132_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
KK132_RS00615	COG1045	serine acetyltransferase
KK132_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KK132_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KK132_RS00635	COG3688	RNA-binding protein containing a PIN domain
KK132_RS00640	COG1595	DNA-templated transcription, initiation
KK132_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KK132_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
KK132_RS00680	COG2813	Specifically methylates the guanine in position
KK132_RS00695	COG1358	cellular component organization or biogenesis
KK132_RS00720	COG0596	Alpha beta hydrolase
KK132_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KK132_RS00830	COG0201	protein transport
KK132_RS00840	COG0024	Methionine aminopeptidase
KK132_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KK132_RS00880	COG1122	ATPase activity
KK132_RS00885	COG1122	ATPase activity
KK132_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KK132_RS00910	COG2226	methyltransferase
KK132_RS00915	COG2318	DinB family
KK132_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
KK132_RS00930	COG0489	protein tyrosine kinase activity
KK132_RS00940	COG2194	sulfuric ester hydrolase activity
KK132_RS00945	COG0726	polysaccharide deacetylase
KK132_RS01005	COG0738	Major facilitator superfamily
KK132_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KK132_RS01020	COG1063	alcohol dehydrogenase
KK132_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
KK132_RS01030	COG0385	Bile acid
KK132_RS01035	COG2819	hydrolase of the alpha beta superfamily
KK132_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK132_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK132_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KK132_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KK132_RS01055	COG2207	Transcriptional regulator
KK132_RS01060	COG3876	Protein conserved in bacteria
KK132_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
KK132_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KK132_RS01075	COG1263	PTS System
KK132_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK132_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KK132_RS01090	COG1683	Conserved Protein
KK132_RS01120	COG1595	DNA-templated transcription, initiation
KK132_RS01125	COG5662	AntiSigma factor
KK132_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KK132_RS01135	COG4856	YbbR-like protein
KK132_RS01170	COG5002	protein histidine kinase activity
KK132_RS01175	COG1136	(ABC) transporter
KK132_RS01180	COG0577	efflux transmembrane transporter activity
KK132_RS01185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KK132_RS01200	COG1346	cytolysis
KK132_RS01205	COG1380	Effector of murein hydrolase LrgA
KK132_RS01210	COG1846	Transcriptional regulator
KK132_RS01215	COG1113	amino acid transport
KK132_RS01220	COG1011	Hydrolase
KK132_RS01225	COG4585	Histidine kinase
KK132_RS01230	COG2197	response regulator
KK132_RS01235	COG1131	(ABC) transporter
KK132_RS01275	COG0531	amino acid
KK132_RS01280	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KK132_RS01295	COG0584	glycerophosphoryl diester phosphodiesterase
KK132_RS01300	COG2271	Major facilitator Superfamily
KK132_RS01310	COG2368	4-hydroxyphenylacetate
KK132_RS01320	COG3409	Peptidoglycan-binding domain 1 protein
KK132_RS01335	COG1397	ADP-ribosylglycohydrolase
KK132_RS01340	COG5444	nuclease activity
KK132_RS01350	COG0371	Dehydrogenase
KK132_RS01360	COG1183	phosphatidylcholine synthase activity
KK132_RS01365	COG0586	Pfam SNARE associated Golgi protein
KK132_RS01370	COG0688	phosphatidylethanolamine metabolic process
KK132_RS01385	COG1301	dicarboxylic acid transport
KK132_RS01390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KK132_RS01395	COG0833	amino acid
KK132_RS01400	COG2040	homocysteine
KK132_RS01405	COG1115	amino acid carrier protein
KK132_RS01410	COG2066	Belongs to the glutaminase family
KK132_RS01415	COG4191	Histidine kinase
KK132_RS01420	COG0784	Response regulator, receiver
KK132_RS01440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KK132_RS01445	COG0778	Nitroreductase
KK132_RS01450	COG0346	lactoylglutathione lyase activity
KK132_RS01455	COG2259	Doxx family
KK132_RS01460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK132_RS01475	COG3773	Cell wall hydrolase
KK132_RS01480	COG3540	Alkaline phosphatase
KK132_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KK132_RS01490	COG0805	protein transport
KK132_RS01500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KK132_RS01505	COG0477	Major facilitator Superfamily
KK132_RS01510	COG1309	transcriptional regulator
KK132_RS01515	COG0252	asparaginase activity
KK132_RS01520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KK132_RS01525	COG3012	SEC-C Motif Domain Protein
KK132_RS01525	COG1405	negative regulation of cell septum assembly
KK132_RS01540	COG1595	DNA-templated transcription, initiation
KK132_RS01545	COG1595	DNA-templated transcription, initiation
KK132_RS01550	COG1876	peptidase activity
KK132_RS01555	COG0457	Tetratricopeptide repeat
KK132_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS01565	COG0366	Alpha amylase catalytic
KK132_RS01570	COG0803	Belongs to the bacterial solute-binding protein 9 family
KK132_RS01575	COG1121	(ABC) transporter
KK132_RS01580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KK132_RS01585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KK132_RS01590	COG2310	stress, protein
KK132_RS01595	COG2310	stress, protein
KK132_RS01600	COG2310	stress, protein
KK132_RS01605	COG0861	Integral membrane protein TerC family
KK132_RS01615	COG3853	Toxic anion resistance protein (TelA)
KK132_RS01620	COG0477	Major facilitator Superfamily
KK132_RS01625	COG4175	Glycine betaine
KK132_RS01625	COG0517	IMP dehydrogenase activity
KK132_RS01630	COG4176	ABC-type proline glycine betaine transport system permease component
KK132_RS01635	COG2113	Glycine betaine
KK132_RS01640	COG1473	amidohydrolase
KK132_RS01645	COG1288	antiporter activity
KK132_RS01665	COG2814	Major facilitator Superfamily
KK132_RS01670	COG1846	Transcriptional regulator
KK132_RS01675	COG1280	lysine exporter protein (LysE YggA)
KK132_RS01680	COG3403	YqcI/YcgG family
KK132_RS01685	COG1113	amino acid transport
KK132_RS01690	COG3665	Urea carboxylase-associated protein
KK132_RS01705	COG1660	Displays ATPase and GTPase activities
KK132_RS01710	COG1082	Xylose isomerase domain protein TIM barrel
KK132_RS01715	COG2271	Major facilitator Superfamily
KK132_RS01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KK132_RS01725	COG3458	cephalosporin-C deacetylase activity
KK132_RS01730	COG3541	Predicted nucleotidyltransferase
KK132_RS01735	COG0506	proline dehydrogenase activity
KK132_RS01740	COG1012	belongs to the aldehyde dehydrogenase family
KK132_RS01745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KK132_RS01750	COG2508	Transcriptional regulator
KK132_RS01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KK132_RS01760	COG1587	Uroporphyrinogen-III synthase
KK132_RS01765	COG2146	nitrite reductase [NAD(P)H] activity
KK132_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KK132_RS01775	COG0243	molybdopterin cofactor binding
KK132_RS01780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KK132_RS01785	COG2223	nitrite transmembrane transporter activity
KK132_RS01790	COG0523	cobalamin synthesis protein
KK132_RS01795	COG1063	alcohol dehydrogenase
KK132_RS01800	COG1714	RDD family
KK132_RS01820	COG3209	COG3209 Rhs family protein
KK132_RS01825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KK132_RS01830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KK132_RS01835	COG1733	regulation of RNA biosynthetic process
KK132_RS01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS01860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS01865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS01870	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KK132_RS01885	COG2364	Membrane
KK132_RS01890	COG1126	abc transporter atp-binding protein
KK132_RS01895	COG0765	amino acid transport
KK132_RS01905	COG0583	DNA-binding transcription factor activity
KK132_RS01910	COG0163	prenyltransferase activity
KK132_RS01915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KK132_RS01930	COG3104	oligopeptide transport
KK132_RS01935	COG5434	Belongs to the glycosyl hydrolase 28 family
KK132_RS01945	COG0697	spore germination
KK132_RS01955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KK132_RS01960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KK132_RS01965	COG0456	acetyltransferase
KK132_RS01970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK132_RS01975	COG0765	amino acid transport
KK132_RS01980	COG1126	abc transporter atp-binding protein
KK132_RS01985	COG1473	amidohydrolase
KK132_RS01990	COG2079	MmgE PrpD family protein
KK132_RS01995	COG1136	(ABC) transporter
KK132_RS02000	COG0577	efflux transmembrane transporter activity
KK132_RS02005	COG0745	RESPONSE REGULATOR receiver
KK132_RS02010	COG5002	protein histidine kinase activity
KK132_RS02010	COG3850	Histidine kinase
KK132_RS02015	COG0457	Tetratricopeptide repeat
KK132_RS02030	COG0527	aspartate kinase activity
KK132_RS02035	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK132_RS02040	COG4605	iron ion homeostasis
KK132_RS02045	COG4604	ABC transporter, ATP-binding protein
KK132_RS02050	COG4607	ABC-type enterochelin transport system periplasmic component
KK132_RS02055	COG2814	Major facilitator Superfamily
KK132_RS02060	COG1309	transcriptional regulator
KK132_RS02065	COG0778	Nitroreductase
KK132_RS02070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KK132_RS02075	COG0640	Transcriptional regulator
KK132_RS02080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KK132_RS02085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KK132_RS02090	COG1012	belongs to the aldehyde dehydrogenase family
KK132_RS02095	COG4975	Glucose uptake
KK132_RS02100	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS02105	COG4549	nuclear export factor GLE1
KK132_RS02110	COG1276	copper resistance
KK132_RS02110	COG2372	response to copper ion
KK132_RS02115	COG1349	DNA-binding transcription factor activity
KK132_RS02125	COG2213	PTS system mannitol-specific
KK132_RS02130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK132_RS02140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KK132_RS02150	COG0561	phosphatase activity
KK132_RS02160	COG1914	H( )-stimulated, divalent metal cation uptake system
KK132_RS02170	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KK132_RS02175	COG1984	allophanate hydrolase subunit 2
KK132_RS02180	COG1414	Transcriptional regulator
KK132_RS02185	COG2755	lipolytic protein G-D-S-L family
KK132_RS02195	COG2329	Antibiotic biosynthesis monooxygenase
KK132_RS02200	COG0768	penicillin binding
KK132_RS02205	COG4989	oxidoreductase activity
KK132_RS02210	COG3711	transcriptional antiterminator
KK132_RS02215	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS02220	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS02225	COG1917	Cupin 2, conserved barrel domain protein
KK132_RS02230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KK132_RS02235	COG3871	stress protein (general stress protein 26)
KK132_RS02245	COG2814	Major facilitator Superfamily
KK132_RS02250	COG1522	sequence-specific DNA binding
KK132_RS02255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KK132_RS02255	COG0551	DNA topoisomerase type I activity
KK132_RS02260	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KK132_RS02265	COG3706	GGDEF domain
KK132_RS02270	COG5298	Protein conserved in bacteria
KK132_RS02275	COG1215	transferase activity, transferring glycosyl groups
KK132_RS02285	COG0531	amino acid
KK132_RS02295	COG0028	Belongs to the TPP enzyme family
KK132_RS02300	COG1388	LysM domain
KK132_RS02300	COG3409	Peptidoglycan-binding domain 1 protein
KK132_RS02300	COG5632	N-Acetylmuramoyl-L-alanine amidase
KK132_RS02320	COG0457	Tetratricopeptide repeat
KK132_RS02350	COG1914	H( )-stimulated, divalent metal cation uptake system
KK132_RS02370	COG2076	Multidrug Resistance protein
KK132_RS02375	COG2217	Heavy metal translocating P-type atpase
KK132_RS02380	COG3729	General stress protein
KK132_RS02385	COG0662	Cupin 2, conserved barrel domain protein
KK132_RS02390	COG2329	Antibiotic biosynthesis monooxygenase
KK132_RS02395	COG3546	catalase activity
KK132_RS02400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KK132_RS02405	COG3290	protein histidine kinase activity
KK132_RS02410	COG4565	transcriptional regulatory protein
KK132_RS02415	COG1301	dicarboxylic acid transport
KK132_RS02420	COG0628	permease
KK132_RS02425	COG1131	(ABC) transporter
KK132_RS02430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KK132_RS02440	COG1960	acyl-CoA dehydrogenase activity
KK132_RS02455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KK132_RS02460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK132_RS02470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KK132_RS02475	COG0513	Belongs to the DEAD box helicase family
KK132_RS02480	COG3402	PFAM membrane-flanked domain
KK132_RS02485	COG3428	Bacterial PH domain
KK132_RS02490	COG0705	Rhomboid family
KK132_RS02500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KK132_RS02505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KK132_RS02510	COG0864	Transcriptional regulator
KK132_RS02515	COG2337	Toxic component of a toxin-antitoxin (TA) module
KK132_RS02520	COG1366	Belongs to the anti-sigma-factor antagonist family
KK132_RS02525	COG1366	Belongs to the anti-sigma-factor antagonist family
KK132_RS02530	COG2172	sigma factor antagonist activity
KK132_RS02535	COG2208	phosphoserine phosphatase activity
KK132_RS02540	COG1366	Belongs to the anti-sigma-factor antagonist family
KK132_RS02550	COG1191	sigma factor activity
KK132_RS02555	COG2208	phosphoserine phosphatase activity
KK132_RS02560	COG2183	response to ionizing radiation
KK132_RS02625	COG5444	nuclease activity
KK132_RS02645	COG0477	Major facilitator Superfamily
KK132_RS02660	COG2030	dehydratase
KK132_RS02670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KK132_RS02675	COG1959	2 iron, 2 sulfur cluster binding
KK132_RS02680	COG2910	NAD(P)H-binding
KK132_RS02685	COG3239	Fatty acid desaturase
KK132_RS02690	COG1278	Cold shock
KK132_RS02695	COG1329	Transcriptional regulator
KK132_RS02700	COG1937	Protein conserved in bacteria
KK132_RS02705	COG2210	Belongs to the sulfur carrier protein TusA family
KK132_RS02710	COG1054	Belongs to the UPF0176 family
KK132_RS02715	COG0425	Belongs to the sulfur carrier protein TusA family
KK132_RS02715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KK132_RS02725	COG0425	Belongs to the sulfur carrier protein TusA family
KK132_RS02730	COG0730	response to heat
KK132_RS02735	COG1794	racemase activity, acting on amino acids and derivatives
KK132_RS02750	COG3621	Patatin-like phospholipase
KK132_RS02760	COG0662	Cupin 2, conserved barrel domain protein
KK132_RS02775	COG0277	FAD linked oxidase domain protein
KK132_RS02800	COG0662	Cupin 2, conserved barrel domain protein
KK132_RS02805	COG2318	DinB family
KK132_RS02835	COG1064	alcohol dehydrogenase
KK132_RS02840	COG0789	Transcriptional regulator
KK132_RS02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KK132_RS02860	COG2814	Major facilitator Superfamily
KK132_RS02865	COG1309	transcriptional regulator
KK132_RS02870	COG0697	spore germination
KK132_RS02875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KK132_RS02880	COG5577	PFAM Coat F domain
KK132_RS02890	COG1063	alcohol dehydrogenase
KK132_RS02895	COG5577	PFAM Coat F domain
KK132_RS02905	COG4585	Histidine kinase
KK132_RS02910	COG2197	response regulator
KK132_RS02915	COG2409	Drug exporters of the RND superfamily
KK132_RS02920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KK132_RS02925	COG0488	(ABC) transporter
KK132_RS02930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KK132_RS02935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KK132_RS02945	COG2814	Major facilitator Superfamily
KK132_RS02950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KK132_RS02960	COG0730	response to heat
KK132_RS02965	COG0456	acetyltransferase
KK132_RS02970	COG0789	Transcriptional regulator
KK132_RS02970	COG4978	Transcriptional regulator
KK132_RS02975	COG0697	spore germination
KK132_RS02980	COG1051	belongs to the nudix hydrolase family
KK132_RS02985	COG2226	methyltransferase
KK132_RS02990	COG0473	3-isopropylmalate dehydrogenase activity
KK132_RS02995	COG1802	Transcriptional regulator
KK132_RS03000	COG1819	glycosyl
KK132_RS03015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KK132_RS03025	COG1388	LysM domain
KK132_RS03030	COG2814	Major facilitator Superfamily
KK132_RS03035	COG2188	Transcriptional regulator
KK132_RS03040	COG2186	Transcriptional regulator
KK132_RS03045	COG2807	transmembrane transport
KK132_RS03050	COG2076	Multidrug Resistance protein
KK132_RS03055	COG2076	Multidrug Resistance protein
KK132_RS03060	COG1309	transcriptional regulator
KK132_RS03065	COG0531	amino acid
KK132_RS03075	COG3832	glyoxalase III activity
KK132_RS03080	COG0604	alcohol dehydrogenase
KK132_RS03085	COG2814	Major facilitator Superfamily
KK132_RS03125	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KK132_RS03130	COG0802	atpase or kinase
KK132_RS03135	COG1214	PFAM Peptidase M22, glycoprotease
KK132_RS03140	COG0456	acetyltransferase
KK132_RS03145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KK132_RS03150	COG0488	(ABC) transporter
KK132_RS03165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KK132_RS03170	COG0805	protein transport
KK132_RS03180	COG1266	CAAX protease self-immunity
KK132_RS03225	COG0457	Tetratricopeptide repeat
KK132_RS03230	COG1063	alcohol dehydrogenase
KK132_RS03235	COG2211	Major facilitator Superfamily
KK132_RS03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KK132_RS03250	COG1842	Phage shock protein A
KK132_RS03255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KK132_RS03260	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KK132_RS03265	COG4260	virion core protein, lumpy skin disease virus
KK132_RS03270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KK132_RS03270	COG2755	lipolytic protein G-D-S-L family
KK132_RS03280	COG1595	DNA-templated transcription, initiation
KK132_RS03285	COG1063	alcohol dehydrogenase
KK132_RS03290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KK132_RS03295	COG0823	Involved in the tonB-independent uptake of proteins
KK132_RS03305	COG2132	Multicopper oxidase
KK132_RS03310	COG1113	amino acid transport
KK132_RS03315	COG0714	Associated with various cellular activities
KK132_RS03320	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KK132_RS03325	COG1305	Transglutaminase-like
KK132_RS03350	COG2252	PERMEase
KK132_RS03355	COG3064	Membrane
KK132_RS03375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KK132_RS03380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KK132_RS03385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KK132_RS03390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KK132_RS03395	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KK132_RS03410	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KK132_RS03420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KK132_RS03425	COG0138	bifunctional purine biosynthesis protein purh
KK132_RS03430	COG0151	Belongs to the GarS family
KK132_RS03440	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KK132_RS03445	COG1470	cell adhesion involved in biofilm formation
KK132_RS03450	COG4496	protein, YerC YecD
KK132_RS03455	COG0069	glutamate synthase activity
KK132_RS03465	COG0210	DNA helicase
KK132_RS03475	COG4851	CamS sex pheromone cAM373 precursor
KK132_RS03480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KK132_RS03485	COG1285	pathogenesis
KK132_RS03490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KK132_RS03510	COG1309	transcriptional regulator
KK132_RS03515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KK132_RS03520	COG1597	lipid kinase activity
KK132_RS03525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KK132_RS03535	COG1131	(ABC) transporter
KK132_RS03575	COG5444	nuclease activity
KK132_RS03605	COG3546	catalase activity
KK132_RS03610	COG0454	-acetyltransferase
KK132_RS03620	COG2323	membrane
KK132_RS03625	COG2329	Antibiotic biosynthesis monooxygenase
KK132_RS03630	COG0346	lactoylglutathione lyase activity
KK132_RS03635	COG1366	Belongs to the anti-sigma-factor antagonist family
KK132_RS03640	COG5583	Uncharacterized small protein (DUF2292)
KK132_RS03645	COG0196	riboflavin kinase activity
KK132_RS03650	COG0670	Belongs to the BI1 family
KK132_RS03655	COG1846	Transcriptional regulator
KK132_RS03660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KK132_RS03670	COG2124	cytochrome p450
KK132_RS03670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KK132_RS03675	COG1368	sulfuric ester hydrolase activity
KK132_RS03680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KK132_RS03685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KK132_RS03690	COG1442	glycosyl transferase family 8
KK132_RS03695	COG1216	Glycosyl transferase, family 2
KK132_RS03700	COG1442	glycosyl transferase family 8
KK132_RS03705	COG2223	nitrite transmembrane transporter activity
KK132_RS03710	COG0531	amino acid
KK132_RS03715	COG1012	belongs to the aldehyde dehydrogenase family
KK132_RS03720	COG0840	transmembrane signaling receptor activity
KK132_RS03725	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS03730	COG0463	Glycosyl transferase, family 2
KK132_RS03730	COG0457	Tetratricopeptide repeat
KK132_RS03735	COG0488	(ABC) transporter
KK132_RS03740	COG0789	Transcriptional regulator
KK132_RS03745	COG2814	Major facilitator Superfamily
KK132_RS03750	COG0488	(ABC) transporter
KK132_RS03755	COG0513	Belongs to the DEAD box helicase family
KK132_RS03760	COG0456	acetyltransferase
KK132_RS03765	COG2130	NADP-dependent
KK132_RS03780	COG3866	Pectate lyase
KK132_RS03785	COG0471	metal ion transport
KK132_RS03810	COG3290	protein histidine kinase activity
KK132_RS03815	COG4565	transcriptional regulatory protein
KK132_RS03820	COG3181	Tripartite tricarboxylate transporter family receptor
KK132_RS03825	COG2851	Citrate transporter
KK132_RS03830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KK132_RS03835	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KK132_RS03845	COG2258	MOSC domain
KK132_RS03865	COG0024	Methionine aminopeptidase
KK132_RS03870	COG1263	PTS System
KK132_RS03870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK132_RS03880	COG1368	sulfuric ester hydrolase activity
KK132_RS03890	COG0071	Belongs to the small heat shock protein (HSP20) family
KK132_RS03905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK132_RS03905	COG1263	PTS System
KK132_RS03910	COG0366	Alpha amylase catalytic
KK132_RS03915	COG2188	Transcriptional regulator
KK132_RS03920	COG0778	Nitroreductase
KK132_RS03935	COG0737	Belongs to the 5'-nucleotidase family
KK132_RS03940	COG0693	protein deglycase activity
KK132_RS03945	COG1609	Transcriptional regulator
KK132_RS03960	COG2814	Major facilitator Superfamily
KK132_RS03970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KK132_RS03975	COG4980	gas vesicle protein
KK132_RS03980	COG1295	ribonuclease BN
KK132_RS03985	COG0477	Major facilitator Superfamily
KK132_RS03990	COG0387	Pfam Sodium calcium exchanger
KK132_RS04000	COG0668	transmembrane transport
KK132_RS04005	COG0535	radical SAM domain protein
KK132_RS04015	COG0726	polysaccharide deacetylase
KK132_RS04035	COG0745	RESPONSE REGULATOR receiver
KK132_RS04040	COG2205	protein histidine kinase activity
KK132_RS04045	COG2084	Dehydrogenase
KK132_RS04055	COG0598	Magnesium transport protein CorA
KK132_RS04060	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KK132_RS04065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KK132_RS04080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KK132_RS04085	COG4637	Psort location Cytoplasmic, score
KK132_RS04090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KK132_RS04095	COG0022	dehydrogenase e1 component
KK132_RS04100	COG0508	dehydrogenase complex catalyzes the overall conversion of
KK132_RS04105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KK132_RS04110	COG3284	Transcriptional regulator
KK132_RS04120	COG1486	melibiose metabolic process
KK132_RS04125	COG1737	Transcriptional regulator
KK132_RS04130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK132_RS04130	COG1263	PTS System
KK132_RS04135	COG5434	Belongs to the glycosyl hydrolase 28 family
KK132_RS04140	COG5434	Belongs to the glycosyl hydrolase 28 family
KK132_RS04145	COG1132	(ABC) transporter
KK132_RS04150	COG1132	(ABC) transporter
KK132_RS04155	COG2259	Doxx family
KK132_RS04160	COG2514	catechol 2,3-dioxygenase activity
KK132_RS04175	COG1695	Transcriptional regulator
KK132_RS04180	COG2249	NAD(P)H dehydrogenase (quinone) activity
KK132_RS04185	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KK132_RS04190	COG3848	Pyruvate phosphate dikinase
KK132_RS04190	COG0574	Belongs to the PEP-utilizing enzyme family
KK132_RS04195	COG2732	(Barnase) inhibitor
KK132_RS04200	COG2318	DinB family
KK132_RS04205	COG2814	Major facilitator Superfamily
KK132_RS04210	COG1846	Transcriptional regulator
KK132_RS04215	COG0392	lysyltransferase activity
KK132_RS04215	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KK132_RS04220	COG0384	phenazine biosynthesis protein PhzF
KK132_RS04225	COG0778	Nitroreductase
KK132_RS04240	COG1090	epimerase
KK132_RS04255	COG2814	Major facilitator Superfamily
KK132_RS04265	COG3591	Belongs to the peptidase S1B family
KK132_RS04280	COG3103	Sh3 type 3 domain protein
KK132_RS04285	COG5658	integral membrane protein
KK132_RS04290	COG0596	Alpha beta hydrolase
KK132_RS04295	COG0463	Glycosyl transferase, family 2
KK132_RS04300	COG4485	Bacterial membrane protein, YfhO
KK132_RS04305	COG1988	membrane-bound metal-dependent
KK132_RS04310	COG1194	a g-specific adenine glycosylase
KK132_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS04340	COG1132	(ABC) transporter
KK132_RS04345	COG4129	membrane
KK132_RS04355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KK132_RS04360	COG0735	belongs to the Fur family
KK132_RS04475	COG3340	Belongs to the peptidase S51 family
KK132_RS04485	COG0277	FAD linked oxidase domain protein
KK132_RS04495	COG0747	negative chemotaxis
KK132_RS04500	COG0601	transmembrane transport
KK132_RS04505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KK132_RS04510	COG0444	Belongs to the ABC transporter superfamily
KK132_RS04515	COG4608	Belongs to the ABC transporter superfamily
KK132_RS04520	COG0753	catalase activity
KK132_RS04530	COG1116	anion transmembrane transporter activity
KK132_RS04535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KK132_RS04540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KK132_RS04560	COG1476	TRANSCRIPTIONal
KK132_RS04570	COG3382	B3 4 domain protein
KK132_RS04575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KK132_RS04585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KK132_RS04590	COG0789	Transcriptional regulator
KK132_RS04595	COG1664	Polymer-forming cytoskeletal
KK132_RS04600	COG1664	Polymer-forming cytoskeletal
KK132_RS04605	COG2766	serine protein kinase
KK132_RS04615	COG1846	Transcriptional regulator
KK132_RS04620	COG1566	PFAM secretion protein HlyD family protein
KK132_RS04625	COG2814	Major facilitator Superfamily
KK132_RS04630	COG0655	NAD(P)H dehydrogenase (quinone) activity
KK132_RS04645	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KK132_RS04650	COG1278	Cold shock
KK132_RS04655	COG1464	Belongs to the NlpA lipoprotein family
KK132_RS04660	COG3706	GGDEF domain
KK132_RS04665	COG1823	symporter activity
KK132_RS04685	COG5577	PFAM Coat F domain
KK132_RS04690	COG0737	Belongs to the 5'-nucleotidase family
KK132_RS04690	COG1525	nuclease
KK132_RS04690	COG4085	toxin activity
KK132_RS04695	COG3764	Sortase (surface protein transpeptidase)
KK132_RS04700	COG0564	pseudouridine synthase activity
KK132_RS04710	COG0517	IMP dehydrogenase activity
KK132_RS04715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KK132_RS04720	COG3153	acetyltransferase
KK132_RS04720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KK132_RS04725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KK132_RS04730	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KK132_RS04735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KK132_RS04745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KK132_RS04750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KK132_RS04755	COG4585	Histidine kinase
KK132_RS04755	COG2203	Gaf domain
KK132_RS04760	COG2197	response regulator
KK132_RS04765	COG0431	NADPH-dependent FMN reductase
KK132_RS04780	COG1388	LysM domain
KK132_RS04780	COG0791	NLP P60 protein
KK132_RS04785	COG1959	2 iron, 2 sulfur cluster binding
KK132_RS04795	COG2719	SpoVR family
KK132_RS04800	COG1785	Belongs to the alkaline phosphatase family
KK132_RS04805	COG0791	NLP P60 protein
KK132_RS04805	COG1388	LysM domain
KK132_RS04810	COG0583	DNA-binding transcription factor activity
KK132_RS04815	COG0372	Belongs to the citrate synthase family
KK132_RS04820	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS04825	COG0531	amino acid
KK132_RS04830	COG0733	neurotransmitter:sodium symporter activity
KK132_RS04845	COG1595	DNA-templated transcription, initiation
KK132_RS04850	COG0204	Acyl-transferase
KK132_RS04855	COG1253	flavin adenine dinucleotide binding
KK132_RS04860	COG0789	Transcriptional regulator
KK132_RS04865	COG0436	Aminotransferase
KK132_RS04870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KK132_RS04875	COG1253	flavin adenine dinucleotide binding
KK132_RS04880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KK132_RS04885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KK132_RS04890	COG0584	glycerophosphoryl diester phosphodiesterase
KK132_RS04900	COG0668	transmembrane transport
KK132_RS04905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KK132_RS04910	COG0726	polysaccharide deacetylase
KK132_RS04915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KK132_RS04920	COG3226	Transcriptional regulator
KK132_RS04930	COG0589	response to stress
KK132_RS04935	COG1132	(ABC) transporter
KK132_RS04940	COG1132	(ABC) transporter
KK132_RS04945	COG0702	epimerase
KK132_RS04965	COG0189	ligase activity
KK132_RS04970	COG0189	ligase activity
KK132_RS04985	COG4335	DNA alkylation repair
KK132_RS04990	COG0561	phosphatase activity
KK132_RS04995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KK132_RS05005	COG0475	glutathione-regulated potassium exporter activity
KK132_RS05010	COG0490	domain, Protein
KK132_RS05020	COG1024	Enoyl-CoA hydratase
KK132_RS05030	COG4152	abc transporter atp-binding protein
KK132_RS05035	COG1668	transmembrane transport
KK132_RS05040	COG0420	3'-5' exonuclease activity
KK132_RS05045	COG4717	serine-type aminopeptidase activity
KK132_RS05060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KK132_RS05095	COG4980	gas vesicle protein
KK132_RS05110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KK132_RS05115	COG0537	adenosine 5'-monophosphoramidase activity
KK132_RS05120	COG1131	(ABC) transporter
KK132_RS05125	COG4473	ABC transporter
KK132_RS05135	COG1473	amidohydrolase
KK132_RS05140	COG3069	C4-dicarboxylate transmembrane transporter activity
KK132_RS05145	COG2329	Antibiotic biosynthesis monooxygenase
KK132_RS05150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KK132_RS05160	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KK132_RS05165	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KK132_RS05170	COG1309	transcriptional regulator
KK132_RS05175	COG1511	domain protein
KK132_RS05180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KK132_RS05190	COG1363	Peptidase, m42
KK132_RS05195	COG1301	dicarboxylic acid transport
KK132_RS05205	COG1234	tRNA 3'-trailer cleavage
KK132_RS05210	COG0095	Lipoate-protein ligase
KK132_RS05215	COG0702	epimerase
KK132_RS05220	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS05230	COG0501	Belongs to the peptidase M48B family
KK132_RS05235	COG1404	Belongs to the peptidase S8 family
KK132_RS05240	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KK132_RS05245	COG0406	alpha-ribazole phosphatase activity
KK132_RS05250	COG0183	Belongs to the thiolase family
KK132_RS05255	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS05260	COG1268	BioY protein
KK132_RS05265	COG0840	transmembrane signaling receptor activity
KK132_RS05270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KK132_RS05270	COG0723	plastoquinol--plastocyanin reductase activity
KK132_RS05275	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS05285	COG4903	ComK protein
KK132_RS05295	COG5646	InterPro IPR014922
KK132_RS05315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KK132_RS05330	COG0398	Pfam SNARE associated Golgi protein
KK132_RS05335	COG0681	Belongs to the peptidase S26 family
KK132_RS05340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KK132_RS05345	COG1846	Transcriptional regulator
KK132_RS05350	COG3180	Ammonia monooxygenase
KK132_RS05355	COG2814	Major facilitator Superfamily
KK132_RS05365	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KK132_RS05370	COG2323	membrane
KK132_RS05385	COG0420	3'-5' exonuclease activity
KK132_RS05390	COG0419	ATPase involved in DNA repair
KK132_RS05395	COG1403	HNH endonuclease
KK132_RS05435	COG0179	Fumarylacetoacetate (FAA) hydrolase
KK132_RS05450	COG0367	asparagine synthase
KK132_RS05455	COG1562	ergosterol biosynthetic process
KK132_RS05460	COG0534	Mate efflux family protein
KK132_RS05465	COG1917	Cupin 2, conserved barrel domain protein
KK132_RS05465	COG2207	Transcriptional regulator
KK132_RS05475	COG2318	DinB family
KK132_RS05480	COG1279	arginine transmembrane transporter activity
KK132_RS05485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KK132_RS05490	COG1357	PFAM Pentapeptide repeats (8 copies)
KK132_RS05495	COG2153	protein acetylation
KK132_RS05500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KK132_RS05500	COG0646	methionine synthase
KK132_RS05510	COG2996	Protein conserved in bacteria
KK132_RS05515	COG1744	ABC transporter substrate-binding protein PnrA-like
KK132_RS05520	COG0840	transmembrane signaling receptor activity
KK132_RS05525	COG2124	cytochrome p450
KK132_RS05535	COG1307	EDD domain protein, DegV family
KK132_RS05540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KK132_RS05560	COG0561	phosphatase activity
KK132_RS05565	COG1073	alpha beta
KK132_RS05570	COG2151	metal-sulfur cluster biosynthetic enzyme
KK132_RS05580	COG0277	FAD linked oxidase domain protein
KK132_RS05585	COG2271	Major facilitator Superfamily
KK132_RS05595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KK132_RS05605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KK132_RS05610	COG0505	Belongs to the CarA family
KK132_RS05615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KK132_RS05620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KK132_RS05635	COG2267	carboxylic ester hydrolase activity
KK132_RS05645	COG1744	ABC transporter substrate-binding protein PnrA-like
KK132_RS05660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KK132_RS05665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KK132_RS05670	COG5504	Zn-dependent protease
KK132_RS05675	COG0444	Belongs to the ABC transporter superfamily
KK132_RS05680	COG4608	Belongs to the ABC transporter superfamily
KK132_RS05690	COG0601	transmembrane transport
KK132_RS05695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KK132_RS05705	COG0180	Tryptophanyl-tRNA synthetase
KK132_RS05710	COG4166	transmembrane transport
KK132_RS05715	COG0601	transmembrane transport
KK132_RS05720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KK132_RS05725	COG0444	Belongs to the ABC transporter superfamily
KK132_RS05730	COG4608	Belongs to the ABC transporter superfamily
KK132_RS05740	COG0456	acetyltransferase
KK132_RS05745	COG1393	Belongs to the ArsC family
KK132_RS05750	COG0861	Integral membrane protein TerC family
KK132_RS05755	COG4862	establishment of competence for transformation
KK132_RS05760	COG4469	Competence protein
KK132_RS05765	COG1164	Oligoendopeptidase f
KK132_RS05775	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KK132_RS05780	COG2346	COG2346, Truncated hemoglobins
KK132_RS05785	COG0741	lytic transglycosylase activity
KK132_RS05790	COG4116	CYTH
KK132_RS05800	COG2357	RelA SpoT domain protein
KK132_RS05805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KK132_RS05810	COG0564	pseudouridine synthase activity
KK132_RS05820	COG0475	glutathione-regulated potassium exporter activity
KK132_RS05820	COG0569	domain protein
KK132_RS05825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KK132_RS05830	COG0352	thiamine-phosphate diphosphorylase activity
KK132_RS05835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KK132_RS05840	COG2104	thiamine diphosphate biosynthetic process
KK132_RS05850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KK132_RS05855	COG0351	phosphomethylpyrimidine kinase
KK132_RS05860	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KK132_RS05915	COG0210	DNA helicase
KK132_RS05935	COG1131	(ABC) transporter
KK132_RS05945	COG2153	protein acetylation
KK132_RS05955	COG2382	esterase
KK132_RS05960	COG0626	cystathionine gamma-synthase activity
KK132_RS05965	COG0626	cystathionine gamma-synthase activity
KK132_RS05995	COG5444	nuclease activity
KK132_RS06005	COG0346	lactoylglutathione lyase activity
KK132_RS06010	COG2367	Beta-lactamase
KK132_RS06015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KK132_RS06020	COG0477	Major facilitator Superfamily
KK132_RS06025	COG1846	Transcriptional regulator
KK132_RS06035	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KK132_RS06040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KK132_RS06045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KK132_RS06050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK132_RS06050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK132_RS06055	COG1447	Phosphotransferase system cellobiose-specific component IIA
KK132_RS06065	COG1349	DNA-binding transcription factor activity
KK132_RS06085	COG1285	pathogenesis
KK132_RS06100	COG2205	protein histidine kinase activity
KK132_RS06110	COG3383	formate dehydrogenase (NAD+) activity
KK132_RS06115	COG2427	Protein of unknown function (DUF1641)
KK132_RS06120	COG2124	cytochrome p450
KK132_RS06125	COG1819	glycosyl
KK132_RS06135	COG1587	Uroporphyrinogen-III synthase
KK132_RS06140	COG0390	transport system, permease component
KK132_RS06145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KK132_RS06150	COG0697	spore germination
KK132_RS06155	COG4297	protein containing double-stranded beta helix domain
KK132_RS06165	COG1252	NADH dehydrogenase
KK132_RS06175	COG2211	Major facilitator Superfamily
KK132_RS06180	COG1609	Transcriptional regulator
KK132_RS06185	COG0246	Mannitol dehydrogenase
KK132_RS06190	COG2721	sulfolactate sulfo-lyase activity
KK132_RS06195	COG0745	RESPONSE REGULATOR receiver
KK132_RS06200	COG2205	protein histidine kinase activity
KK132_RS06200	COG2770	Histidine kinase
KK132_RS06220	COG4585	Histidine kinase
KK132_RS06225	COG2197	response regulator
KK132_RS06260	COG0730	response to heat
KK132_RS06265	COG2318	DinB family
KK132_RS06270	COG0457	Tetratricopeptide repeat
KK132_RS06280	COG1388	LysM domain
KK132_RS06280	COG5632	N-Acetylmuramoyl-L-alanine amidase
KK132_RS06280	COG3409	Peptidoglycan-binding domain 1 protein
KK132_RS06290	COG4195	phage-related replication protein
KK132_RS06295	COG2856	Zn peptidase
KK132_RS06300	COG1396	sequence-specific DNA binding
KK132_RS06310	COG1522	sequence-specific DNA binding
KK132_RS06315	COG1484	DNA-dependent DNA replication
KK132_RS06335	COG1595	DNA-templated transcription, initiation
KK132_RS06340	COG5484	DNA packaging
KK132_RS06340	COG3728	DNA packaging
KK132_RS06345	COG1783	phage Terminase large subunit
KK132_RS06350	COG5518	Phage portal protein
KK132_RS06355	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KK132_RS06360	COG4653	Phage capsid family
KK132_RS06410	COG3953	SLT domain
KK132_RS06410	COG5412	phage tail tape measure protein
KK132_RS06410	COG3953	SLT domain
KK132_RS06410	COG5412	phage tail tape measure protein
KK132_RS06410	COG3953	SLT domain
KK132_RS06410	COG5412	phage tail tape measure protein
KK132_RS06415	COG1652	LysM domain
KK132_RS06420	COG4193	domain, Protein
KK132_RS06430	COG3628	GPW Gp25 family protein
KK132_RS06435	COG3299	homolog of phage Mu protein gp47
KK132_RS06440	COG3778	Protein conserved in bacteria
KK132_RS06480	COG3409	Peptidoglycan-binding domain 1 protein
KK132_RS06480	COG5632	N-Acetylmuramoyl-L-alanine amidase
KK132_RS06500	COG0306	phosphate transporter
KK132_RS06505	COG1392	Phosphate transport regulator
KK132_RS06510	COG0531	amino acid
KK132_RS06515	COG0346	lactoylglutathione lyase activity
KK132_RS06520	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KK132_RS06525	COG0463	Glycosyl transferase, family 2
KK132_RS06535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KK132_RS06540	COG0477	Major facilitator Superfamily
KK132_RS06545	COG2362	D-Aminopeptidase
KK132_RS06550	COG0601	transmembrane transport
KK132_RS06555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KK132_RS06560	COG0444	Belongs to the ABC transporter superfamily
KK132_RS06565	COG4166	transmembrane transport
KK132_RS06570	COG1619	proteins homologs of microcin C7 resistance protein MccF
KK132_RS06575	COG4948	Mandelate Racemase Muconate Lactonizing
KK132_RS06580	COG0791	NLP P60 protein
KK132_RS06585	COG4608	Belongs to the ABC transporter superfamily
KK132_RS06590	COG2706	6-phosphogluconolactonase activity
KK132_RS06595	COG1834	amidinotransferase
KK132_RS06600	COG1607	acyl-coa hydrolase
KK132_RS06605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KK132_RS06610	COG2076	Multidrug Resistance protein
KK132_RS06615	COG2076	Multidrug Resistance protein
KK132_RS06620	COG0788	formyltetrahydrofolate deformylase activity
KK132_RS06625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KK132_RS06635	COG1764	response to oxidative stress
KK132_RS06640	COG1846	Transcriptional regulator
KK132_RS06645	COG1764	response to oxidative stress
KK132_RS06660	COG0463	Glycosyl transferase, family 2
KK132_RS06660	COG0457	Tetratricopeptide repeat
KK132_RS06685	COG1404	Belongs to the peptidase S8 family
KK132_RS06690	COG1366	Belongs to the anti-sigma-factor antagonist family
KK132_RS06695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KK132_RS06700	COG1122	ATPase activity
KK132_RS06705	COG4721	ABC-type cobalt transport system, permease component
KK132_RS06710	COG1388	LysM domain
KK132_RS06710	COG3858	chitin binding
KK132_RS06720	COG2239	Acts as a magnesium transporter
KK132_RS06725	COG0789	Transcriptional regulator
KK132_RS06740	COG1846	Transcriptional regulator
KK132_RS06745	COG0726	polysaccharide deacetylase
KK132_RS06750	COG1793	dna ligase
KK132_RS06750	COG3285	dna ligase
KK132_RS06755	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KK132_RS06760	COG0586	Pfam SNARE associated Golgi protein
KK132_RS06770	COG1191	sigma factor activity
KK132_RS06795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KK132_RS06800	COG2323	membrane
KK132_RS06810	COG3594	Acyltransferase
KK132_RS06815	COG5002	protein histidine kinase activity
KK132_RS06820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KK132_RS06840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KK132_RS06845	COG0436	Aminotransferase
KK132_RS06875	COG3852	Histidine kinase
KK132_RS06880	COG1846	Transcriptional regulator
KK132_RS06885	COG1360	Flagellar Motor Protein
KK132_RS06890	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KK132_RS06895	COG0542	response to heat
KK132_RS06900	COG3949	Membrane
KK132_RS06915	COG0720	synthase
KK132_RS06920	COG0602	queuosine metabolic process
KK132_RS06935	COG1733	regulation of RNA biosynthetic process
KK132_RS06940	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS06955	COG4873	Protein conserved in bacteria
KK132_RS06965	COG3773	Cell wall hydrolase
KK132_RS06970	COG2244	polysaccharide biosynthetic process
KK132_RS06975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK132_RS06980	COG2217	Heavy metal translocating P-type atpase
KK132_RS06985	COG0006	proline dipeptidase activity
KK132_RS06995	COG1609	Transcriptional regulator
KK132_RS07000	COG3711	transcriptional antiterminator
KK132_RS07005	COG1263	PTS System
KK132_RS07005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK132_RS07005	COG2190	(PTS) system
KK132_RS07010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK132_RS07015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KK132_RS07025	COG1533	DNA photolyase activity
KK132_RS07030	COG0840	transmembrane signaling receptor activity
KK132_RS07035	COG2084	Dehydrogenase
KK132_RS07040	COG2340	Cysteine-rich secretory protein family
KK132_RS07045	COG0768	penicillin binding
KK132_RS07050	COG4191	Histidine kinase
KK132_RS07055	COG0436	Aminotransferase
KK132_RS07065	COG0784	Response regulator, receiver
KK132_RS07065	COG0835	chemotaxis
KK132_RS07075	COG2814	Major facilitator Superfamily
KK132_RS07080	COG1376	ErfK ybiS ycfS ynhG family protein
KK132_RS07085	COG1408	metallophosphoesterase
KK132_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS07100	COG2200	EAL domain
KK132_RS07105	COG4703	Protein of unknown function (DUF1797)
KK132_RS07110	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KK132_RS07120	COG0517	IMP dehydrogenase activity
KK132_RS07125	COG0583	DNA-binding transcription factor activity
KK132_RS07130	COG0716	FMN binding
KK132_RS07140	COG0716	FMN binding
KK132_RS07160	COG0668	transmembrane transport
KK132_RS07165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK132_RS07185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KK132_RS07190	COG0303	'Molybdopterin
KK132_RS07195	COG1763	Mo-molybdopterin cofactor biosynthetic process
KK132_RS07200	COG0314	molybdopterin synthase activity
KK132_RS07205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KK132_RS07215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KK132_RS07220	COG1136	(ABC) transporter
KK132_RS07225	COG0577	efflux transmembrane transporter activity
KK132_RS07230	COG1349	DNA-binding transcription factor activity
KK132_RS07235	COG1105	Belongs to the carbohydrate kinase PfkB family
KK132_RS07240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KK132_RS07240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KK132_RS07240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK132_RS07245	COG0681	Belongs to the peptidase S26 family
KK132_RS07255	COG0488	(ABC) transporter
KK132_RS07260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KK132_RS07265	COG2309	aminopeptidase activity
KK132_RS07275	COG1077	Cell shape determining protein MreB Mrl
KK132_RS07280	COG2002	toxin-antitoxin pair type II binding
KK132_RS07285	COG3852	Histidine kinase
KK132_RS07290	COG2105	PFAM AIG2 family protein
KK132_RS07290	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KK132_RS07295	COG0569	domain protein
KK132_RS07305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KK132_RS07315	COG0561	phosphatase activity
KK132_RS07320	COG0242	peptide deformylase activity
KK132_RS07330	COG0497	DNA recombination
KK132_RS07335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KK132_RS07335	COG2070	2-Nitropropane dioxygenase
KK132_RS07340	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS07340	COG3321	synthase
KK132_RS07340	COG4221	oxidoreductase activity
KK132_RS07340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS07345	COG0300	oxidoreductase activity
KK132_RS07345	COG3321	synthase
KK132_RS07345	COG4221	oxidoreductase activity
KK132_RS07345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS07350	COG4221	oxidoreductase activity
KK132_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS07350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS07350	COG3321	synthase
KK132_RS07355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS07355	COG0300	oxidoreductase activity
KK132_RS07355	COG3321	synthase
KK132_RS07355	COG4221	oxidoreductase activity
KK132_RS07360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS07360	COG0300	oxidoreductase activity
KK132_RS07360	COG3321	synthase
KK132_RS07360	COG4221	oxidoreductase activity
KK132_RS07365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS07365	COG0300	oxidoreductase activity
KK132_RS07365	COG4221	oxidoreductase activity
KK132_RS07365	COG3321	synthase
KK132_RS07370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS07370	COG3321	synthase
KK132_RS07370	COG4221	oxidoreductase activity
KK132_RS07375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KK132_RS07380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KK132_RS07385	COG0022	dehydrogenase e1 component
KK132_RS07390	COG0508	dehydrogenase complex catalyzes the overall conversion of
KK132_RS07395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KK132_RS07400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK132_RS07415	COG1982	Orn Lys Arg decarboxylase major
KK132_RS07435	COG0483	inositol monophosphate 1-phosphatase activity
KK132_RS07445	COG3227	Zinc metalloprotease (Elastase)
KK132_RS07450	COG1595	DNA-templated transcription, initiation
KK132_RS07470	COG1217	gtp-binding protein TYPA
KK132_RS07480	COG4896	Protein conserved in bacteria
KK132_RS07490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KK132_RS07495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KK132_RS07500	COG2066	Belongs to the glutaminase family
KK132_RS07510	COG0772	Belongs to the SEDS family
KK132_RS07515	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KK132_RS07530	COG2010	Cytochrome c
KK132_RS07530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KK132_RS07535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KK132_RS07540	COG1845	cytochrome c oxidase, subunit III
KK132_RS07545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KK132_RS07550	COG3336	cytochrome c oxidase
KK132_RS07560	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KK132_RS07565	COG2340	Cysteine-rich secretory protein family
KK132_RS07580	COG3679	Belongs to the UPF0342 family
KK132_RS07590	COG0742	ribosomal rna small subunit methyltransferase
KK132_RS07600	COG3314	Sporulation integral membrane protein YlbJ
KK132_RS07605	COG1752	Esterase of the alpha-beta hydrolase superfamily
KK132_RS07610	COG3480	Lon protease (S16) C-terminal proteolytic domain
KK132_RS07620	COG1399	metal-binding, possibly nucleic acid-binding protein
KK132_RS07640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KK132_RS07660	COG4839	cell division protein FtsL
KK132_RS07665	COG0768	penicillin binding
KK132_RS07670	COG0768	penicillin binding
KK132_RS07690	COG0772	Belongs to the SEDS family
KK132_RS07705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KK132_RS07710	COG0849	cell division
KK132_RS07715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KK132_RS07720	COG1404	Belongs to the peptidase S8 family
KK132_RS07720	COG4412	M6 family metalloprotease domain protein
KK132_RS07730	COG1191	sigma factor activity
KK132_RS07735	COG1191	sigma factor activity
KK132_RS07740	COG1119	ATPase activity
KK132_RS07745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KK132_RS07750	COG1873	PFAM PRC-barrel domain
KK132_RS07755	COG1496	oxidoreductase activity
KK132_RS07760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KK132_RS07770	COG0762	integral membrane protein
KK132_RS07775	COG2302	S4 RNA-binding domain
KK132_RS07780	COG3599	regulation of cell shape
KK132_RS07785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KK132_RS07790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KK132_RS07800	COG0564	pseudouridine synthase activity
KK132_RS07810	COG2233	PERMEase
KK132_RS07820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KK132_RS07825	COG0505	Belongs to the CarA family
KK132_RS07830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KK132_RS07845	COG0284	orotidine-5'-phosphate decarboxylase activity
KK132_RS07850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KK132_RS07860	COG0306	phosphate transporter
KK132_RS07875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KK132_RS07880	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KK132_RS07885	COG1648	precorrin-2 dehydrogenase activity
KK132_RS07895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KK132_RS07900	COG1561	YicC-like family, N-terminal region
KK132_RS07910	COG0194	GDP metabolic process
KK132_RS07920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KK132_RS07925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KK132_RS07930	COG0242	peptide deformylase activity
KK132_RS07940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KK132_RS07940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KK132_RS07950	COG0631	protein serine/threonine phosphatase activity
KK132_RS07955	COG0515	serine threonine protein kinase
KK132_RS07955	COG2815	serine threonine protein kinase
KK132_RS07965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KK132_RS07970	COG1564	THIamine pyrophosphokinase
KK132_RS07985	COG1302	Protein conserved in bacteria
KK132_RS07990	COG1461	Dihydroxyacetone kinase
KK132_RS07995	COG1760	l-serine dehydratase
KK132_RS08000	COG1760	l-serine dehydratase
KK132_RS08005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KK132_RS08020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KK132_RS08025	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS08040	COG1196	nuclear chromosome segregation
KK132_RS08045	COG0552	protein localization to endoplasmic reticulum
KK132_RS08060	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KK132_RS08070	COG1837	Belongs to the UPF0109 family
KK132_RS08095	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KK132_RS08110	COG2257	FlhB HrpN YscU SpaS Family
KK132_RS08120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KK132_RS08125	COG0758	DNA mediated transformation
KK132_RS08130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KK132_RS08140	COG4974	Belongs to the 'phage' integrase family
KK132_RS08160	COG1815	bacterial-type flagellum-dependent cell motility
KK132_RS08165	COG1558	bacterial-type flagellum-dependent cell motility
KK132_RS08170	COG1677	Flagellar hook-basal body complex protein FliE
KK132_RS08175	COG1766	The M ring may be actively involved in energy transduction
KK132_RS08180	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KK132_RS08185	COG1317	bacterial-type flagellum organization
KK132_RS08190	COG1157	protein secretion by the type III secretion system
KK132_RS08195	COG2882	bacterial-type flagellum organization
KK132_RS08200	COG3334	PFAM MgtE intracellular
KK132_RS08205	COG3144	bacterial-type flagellum assembly
KK132_RS08210	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KK132_RS08215	COG4786	Flagellar basal body rod
KK132_RS08220	COG1582	Flagellar protein (FlbD)
KK132_RS08225	COG1580	Controls the rotational direction of flagella during chemotaxis
KK132_RS08230	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KK132_RS08235	COG1776	CheC inhibitor of MCP methylation
KK132_RS08235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KK132_RS08240	COG2201	protein-glutamate methylesterase activity
KK132_RS08245	COG3190	flagellar
KK132_RS08250	COG1338	Plays a role in the flagellum-specific transport system
KK132_RS08255	COG1987	bacterial-type flagellum assembly
KK132_RS08260	COG1684	flagellar biosynthetic protein fliR
KK132_RS08265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KK132_RS08270	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KK132_RS08275	COG1419	protein localization to endoplasmic reticulum
KK132_RS08280	COG0455	bacterial-type flagellum organization
KK132_RS08285	COG2201	protein-glutamate methylesterase activity
KK132_RS08290	COG0643	Histidine kinase
KK132_RS08290	COG2198	Histidine kinase
KK132_RS08295	COG0835	chemotaxis
KK132_RS08300	COG1776	CheC inhibitor of MCP methylation
KK132_RS08310	COG1191	sigma factor activity
KK132_RS08340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KK132_RS08345	COG4589	Belongs to the CDS family
KK132_RS08355	COG0750	zinc metalloprotease
KK132_RS08375	COG0195	Participates in both transcription termination and antitermination
KK132_RS08380	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KK132_RS08385	COG1358	cellular component organization or biogenesis
KK132_RS08395	COG1550	Protein conserved in bacteria
KK132_RS08410	COG0196	riboflavin kinase activity
KK132_RS08425	COG0726	polysaccharide deacetylase
KK132_RS08430	COG0612	Peptidase, M16
KK132_RS08435	COG1873	PFAM PRC-barrel domain
KK132_RS08440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KK132_RS08445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KK132_RS08450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KK132_RS08455	COG0527	aspartate kinase activity
KK132_RS08465	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KK132_RS08470	COG0740	serine-type endopeptidase activity
KK132_RS08480	COG1674	ftsk spoiiie
KK132_RS08480	COG4980	gas vesicle protein
KK132_RS08485	COG2188	Transcriptional regulator
KK132_RS08490	COG2814	Major facilitator Superfamily
KK132_RS08495	COG1846	Transcriptional regulator
KK132_RS08500	COG1033	growth of symbiont in host cell
KK132_RS08500	COG2409	Drug exporters of the RND superfamily
KK132_RS08505	COG0612	Peptidase, M16
KK132_RS08510	COG0612	Peptidase, M16
KK132_RS08515	COG0300	oxidoreductase activity
KK132_RS08530	COG1426	Protein conserved in bacteria
KK132_RS08535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KK132_RS08550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KK132_RS08560	COG1692	metallophosphoesterase
KK132_RS08565	COG2359	stage V sporulation protein S
KK132_RS08585	COG4550	Control of competence regulator ComK, YlbF/YmcA
KK132_RS08630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS08635	COG3425	synthase
KK132_RS08640	COG1024	Enoyl-CoA hydratase
KK132_RS08645	COG1024	Enoyl-CoA hydratase
KK132_RS08650	COG0300	oxidoreductase activity
KK132_RS08650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS08650	COG3321	synthase
KK132_RS08650	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS08655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS08655	COG0300	oxidoreductase activity
KK132_RS08655	COG3321	synthase
KK132_RS08655	COG4221	oxidoreductase activity
KK132_RS08660	COG3321	synthase
KK132_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS08660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KK132_RS08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS08660	COG3321	synthase
KK132_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS08660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KK132_RS08670	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KK132_RS08670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS08670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KK132_RS08670	COG3321	synthase
KK132_RS08675	COG2124	cytochrome p450
KK132_RS08680	COG3209	COG3209 Rhs family protein
KK132_RS08685	COG3619	membrane
KK132_RS08695	COG1404	Belongs to the peptidase S8 family
KK132_RS08705	COG4195	phage-related replication protein
KK132_RS08710	COG1764	response to oxidative stress
KK132_RS08720	COG2076	Multidrug Resistance protein
KK132_RS08760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KK132_RS08765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KK132_RS08770	COG4112	unkown
KK132_RS08775	COG0860	N-Acetylmuramoyl-L-alanine amidase
KK132_RS08780	COG0464	growth
KK132_RS08785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KK132_RS08790	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KK132_RS08795	COG0789	Transcriptional regulator
KK132_RS08800	COG0174	glutamine synthetase
KK132_RS08845	COG2211	Major facilitator Superfamily
KK132_RS08850	COG3507	Belongs to the glycosyl hydrolase 43 family
KK132_RS08865	COG1070	Carbohydrate kinase
KK132_RS08870	COG0574	Belongs to the PEP-utilizing enzyme family
KK132_RS08870	COG3848	Pyruvate phosphate dikinase
KK132_RS08890	COG2318	DinB family
KK132_RS08895	COG1064	alcohol dehydrogenase
KK132_RS08900	COG4451	ribulose bisphosphate carboxylase, small
KK132_RS08900	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KK132_RS08945	COG3397	chitin binding
KK132_RS08965	COG5434	Belongs to the glycosyl hydrolase 28 family
KK132_RS08970	COG0756	dUTP diphosphatase activity
KK132_RS08980	COG4195	phage-related replication protein
KK132_RS09015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KK132_RS09025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KK132_RS09045	COG0785	Cytochrome C biogenesis protein
KK132_RS09050	COG2201	protein-glutamate methylesterase activity
KK132_RS09055	COG4846	Membrane protein involved in cytochrome C biogenesis
KK132_RS09065	COG0071	Belongs to the small heat shock protein (HSP20) family
KK132_RS09080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KK132_RS09085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK132_RS09105	COG0824	Thioesterase
KK132_RS09115	COG4841	protein insertion into membrane
KK132_RS09125	COG1832	CoA-binding protein
KK132_RS09130	COG0187	DNA topoisomerase II activity
KK132_RS09135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KK132_RS09150	COG1115	amino acid carrier protein
KK132_RS09160	COG1063	alcohol dehydrogenase
KK132_RS09165	COG0800	Aldolase
KK132_RS09170	COG1312	Catalyzes the dehydration of D-mannonate
KK132_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS09180	COG1609	Transcriptional regulator
KK132_RS09185	COG2271	Major facilitator Superfamily
KK132_RS09230	COG2205	protein histidine kinase activity
KK132_RS09235	COG0745	RESPONSE REGULATOR receiver
KK132_RS09245	COG3507	Belongs to the glycosyl hydrolase 43 family
KK132_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS09275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KK132_RS09280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KK132_RS09285	COG2610	gluconate transmembrane transporter activity
KK132_RS09290	COG2124	cytochrome p450
KK132_RS09310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KK132_RS09320	COG2246	polysaccharide biosynthetic process
KK132_RS09330	COG0586	Pfam SNARE associated Golgi protein
KK132_RS09335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KK132_RS09340	COG1024	Enoyl-CoA hydratase
KK132_RS09345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KK132_RS09350	COG0511	ligase activity, forming carbon-carbon bonds
KK132_RS09355	COG0439	Biotin carboxylase
KK132_RS09360	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS09365	COG1960	acyl-CoA dehydrogenase activity
KK132_RS09370	COG1649	PFAM Uncharacterised BCR, COG1649
KK132_RS09380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS09380	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KK132_RS09385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS09390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS09400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS09405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS09410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS09415	COG2027	D-alanyl-D-alanine carboxypeptidase
KK132_RS09420	COG2017	converts alpha-aldose to the beta-anomer
KK132_RS09425	COG0534	Mate efflux family protein
KK132_RS09440	COG0582	viral genome integration into host DNA
KK132_RS09445	COG0166	Belongs to the GPI family
KK132_RS09450	COG0405	Gamma-glutamyltransferase
KK132_RS09455	COG2814	Major facilitator Superfamily
KK132_RS09460	COG0640	Transcriptional regulator
KK132_RS09465	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KK132_RS09475	COG0604	alcohol dehydrogenase
KK132_RS09480	COG0493	'glutamate synthase
KK132_RS09485	COG0067	glutamate synthase
KK132_RS09485	COG0069	glutamate synthase activity
KK132_RS09485	COG0070	glutamate synthase
KK132_RS09490	COG0583	DNA-binding transcription factor activity
KK132_RS09495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KK132_RS09510	COG0300	oxidoreductase activity
KK132_RS09515	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KK132_RS09525	COG2814	Major facilitator Superfamily
KK132_RS09530	COG1070	Carbohydrate kinase
KK132_RS09535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KK132_RS09540	COG0243	molybdopterin cofactor binding
KK132_RS09570	COG5444	nuclease activity
KK132_RS09575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KK132_RS09580	COG2207	Transcriptional regulator
KK132_RS09580	COG0662	Cupin 2, conserved barrel domain protein
KK132_RS09585	COG1309	transcriptional regulator
KK132_RS09590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KK132_RS09600	COG0640	Transcriptional regulator
KK132_RS09605	COG0741	lytic transglycosylase activity
KK132_RS09610	COG2322	membrane
KK132_RS09625	COG1619	proteins homologs of microcin C7 resistance protein MccF
KK132_RS09635	COG1388	LysM domain
KK132_RS09635	COG3584	3D domain protein
KK132_RS09640	COG0514	ATP-dependent DNA helicase (RecQ)
KK132_RS09650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KK132_RS09655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KK132_RS09670	COG0071	Belongs to the small heat shock protein (HSP20) family
KK132_RS09700	COG1012	belongs to the aldehyde dehydrogenase family
KK132_RS09705	COG1657	PFAM Prenyltransferase squalene oxidase
KK132_RS09710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KK132_RS09715	COG0733	neurotransmitter:sodium symporter activity
KK132_RS09720	COG0385	Bile acid
KK132_RS09725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KK132_RS09730	COG0508	dehydrogenase complex catalyzes the overall conversion of
KK132_RS09740	COG4548	von Willebrand factor, type A
KK132_RS09745	COG0714	Associated with various cellular activities
KK132_RS09750	COG2032	superoxide dismutase activity
KK132_RS09755	COG0791	NLP P60 protein
KK132_RS09755	COG1388	LysM domain
KK132_RS09760	COG1819	glycosyl
KK132_RS09765	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KK132_RS09770	COG0534	Mate efflux family protein
KK132_RS09775	COG1366	Belongs to the anti-sigma-factor antagonist family
KK132_RS09780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KK132_RS09785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KK132_RS09795	COG2962	Rard protein
KK132_RS09810	COG1942	4-Oxalocrotonate Tautomerase
KK132_RS09820	COG1733	regulation of RNA biosynthetic process
KK132_RS09825	COG0778	Nitroreductase
KK132_RS09830	COG0400	carboxylic ester hydrolase activity
KK132_RS09835	COG0346	lactoylglutathione lyase activity
KK132_RS09845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KK132_RS09855	COG2723	6-phospho-beta-galactosidase activity
KK132_RS09860	COG2188	Transcriptional regulator
KK132_RS09865	COG0793	Belongs to the peptidase S41A family
KK132_RS09865	COG3409	Peptidoglycan-binding domain 1 protein
KK132_RS09870	COG2226	methyltransferase
KK132_RS09880	COG1876	peptidase activity
KK132_RS09900	COG0671	phosphoesterase, PA-phosphatase related
KK132_RS09930	COG1509	lysine 2,3-aminomutase activity
KK132_RS09935	COG0456	acetyltransferase
KK132_RS09940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KK132_RS09945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KK132_RS09950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KK132_RS09955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KK132_RS09960	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KK132_RS09970	COG0456	acetyltransferase
KK132_RS09975	COG0463	Glycosyl transferase, family 2
KK132_RS09990	COG4641	Protein conserved in bacteria
KK132_RS10000	COG1086	Polysaccharide biosynthesis protein
KK132_RS10035	COG0457	Tetratricopeptide repeat
KK132_RS10045	COG3391	amine dehydrogenase activity
KK132_RS10065	COG5444	nuclease activity
KK132_RS10070	COG4282	regulation of fungal-type cell wall biogenesis
KK132_RS10075	COG1525	nuclease
KK132_RS10100	COG1846	Transcriptional regulator
KK132_RS10105	COG4698	Protein conserved in bacteria
KK132_RS10110	COG2755	lipolytic protein G-D-S-L family
KK132_RS10115	COG1999	signal sequence binding
KK132_RS10125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KK132_RS10130	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KK132_RS10135	COG1272	protein, Hemolysin III
KK132_RS10140	COG0204	Acyl-transferase
KK132_RS10145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KK132_RS10160	COG2521	methyltransferase
KK132_RS10160	COG2136	Putative SAM-dependent methyltransferase
KK132_RS10175	COG1413	lyase activity
KK132_RS10180	COG1418	mRNA catabolic process
KK132_RS10185	COG0386	Belongs to the glutathione peroxidase family
KK132_RS10195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KK132_RS10205	COG1278	Cold shock
KK132_RS10225	COG0328	RNA-DNA hybrid ribonuclease activity
KK132_RS10230	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KK132_RS10235	COG0328	RNA-DNA hybrid ribonuclease activity
KK132_RS10245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KK132_RS10260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KK132_RS10270	COG1755	Isoprenylcysteine carboxyl methyltransferase
KK132_RS10275	COG3424	synthase
KK132_RS10300	COG1335	isochorismatase
KK132_RS10310	COG2233	PERMEase
KK132_RS10320	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KK132_RS10325	COG1199	ATP-dependent helicase activity
KK132_RS10340	COG0116	Belongs to the methyltransferase superfamily
KK132_RS10370	COG3359	exonuclease
KK132_RS10375	COG1205	dead DEAH box helicase
KK132_RS10375	COG1111	helicase
KK132_RS10380	COG2190	(PTS) system
KK132_RS10385	COG0071	Belongs to the small heat shock protein (HSP20) family
KK132_RS10425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KK132_RS10425	COG4499	WXG100 protein secretion system (Wss), protein YukC
KK132_RS10435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KK132_RS10440	COG3935	DnaD domain protein
KK132_RS10450	COG0436	Aminotransferase
KK132_RS10455	COG5353	protein conserved in bacteria
KK132_RS10465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KK132_RS10465	COG1199	ATP-dependent helicase activity
KK132_RS10495	COG0438	transferase activity, transferring glycosyl groups
KK132_RS10500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KK132_RS10515	COG1694	Mazg nucleotide pyrophosphohydrolase
KK132_RS10520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KK132_RS10535	COG4347	Protein of unknown function (DUF1405)
KK132_RS10540	COG2010	Cytochrome c
KK132_RS10540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KK132_RS10545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KK132_RS10550	COG0723	plastoquinol--plastocyanin reductase activity
KK132_RS10565	COG0457	Tetratricopeptide repeat
KK132_RS10575	COG0287	Prephenate dehydrogenase
KK132_RS10610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KK132_RS10615	COG4401	Chorismate mutase type I
KK132_RS10630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KK132_RS10635	COG0105	UTP biosynthetic process
KK132_RS10640	COG0142	geranyltranstransferase activity
KK132_RS10650	COG0142	geranyltranstransferase activity
KK132_RS10665	COG0776	regulation of translation
KK132_RS10670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KK132_RS10710	COG0539	negative regulation of cytoplasmic translation
KK132_RS10725	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KK132_RS10730	COG2959	enzyme of heme biosynthesis
KK132_RS10735	COG3409	Peptidoglycan-binding domain 1 protein
KK132_RS10735	COG3773	Cell wall hydrolase
KK132_RS10740	COG2339	peptidase activity
KK132_RS10745	COG0492	ferredoxin-NADP+ reductase activity
KK132_RS10750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KK132_RS10755	COG4862	establishment of competence for transformation
KK132_RS10760	COG1408	metallophosphoesterase
KK132_RS10770	COG1388	LysM domain
KK132_RS10775	COG1266	CAAX protease self-immunity
KK132_RS10780	COG0514	ATP-dependent DNA helicase (RecQ)
KK132_RS10785	COG4955	Helix-turn-helix domain
KK132_RS10790	COG1141	Ferredoxin
KK132_RS10795	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KK132_RS10800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KK132_RS10810	COG1595	DNA-templated transcription, initiation
KK132_RS10815	COG5002	protein histidine kinase activity
KK132_RS10820	COG0745	RESPONSE REGULATOR receiver
KK132_RS10825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KK132_RS10830	COG1333	cytochrome c biogenesis protein
KK132_RS10835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK132_RS10840	COG1187	pseudouridine synthase activity
KK132_RS10845	COG0700	Nucleoside recognition
KK132_RS10850	COG2715	membrane protein required for spore maturation
KK132_RS10855	COG1686	Belongs to the peptidase S11 family
KK132_RS10880	COG1547	Domain of unknown function (DUF309)
KK132_RS10885	COG0456	acetyltransferase
KK132_RS10900	COG0307	riboflavin synthase, alpha
KK132_RS10905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KK132_RS10905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KK132_RS10915	COG0681	Belongs to the peptidase S26 family
KK132_RS10925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KK132_RS10930	COG4086	secreted protein
KK132_RS10935	COG0019	diaminopimelate decarboxylase activity
KK132_RS10940	COG0697	spore germination
KK132_RS10955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KK132_RS10975	COG1191	sigma factor activity
KK132_RS10985	COG1366	Belongs to the anti-sigma-factor antagonist family
KK132_RS10990	COG1686	Belongs to the peptidase S11 family
KK132_RS10995	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KK132_RS11000	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KK132_RS11005	COG4974	Belongs to the 'phage' integrase family
KK132_RS11015	COG0735	belongs to the Fur family
KK132_RS11020	COG1300	Membrane
KK132_RS11035	COG0281	malic enzyme
KK132_RS11040	COG1757	Na H antiporter
KK132_RS11045	COG1027	Aspartate ammonia-lyase
KK132_RS11050	COG0252	asparaginase activity
KK132_RS11055	COG1396	sequence-specific DNA binding
KK132_RS11060	COG1379	DNA repair
KK132_RS11065	COG0494	nUDIX hydrolase
KK132_RS11075	COG0667	Aldo Keto reductase
KK132_RS11085	COG1073	alpha beta
KK132_RS11095	COG4918	Iron-sulphur cluster biosynthesis
KK132_RS11100	COG0456	acetyltransferase
KK132_RS11100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KK132_RS11105	COG2329	Antibiotic biosynthesis monooxygenase
KK132_RS11110	COG0456	acetyltransferase
KK132_RS11115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KK132_RS11130	COG0628	permease
KK132_RS11140	COG0346	lactoylglutathione lyase activity
KK132_RS11150	COG3048	D-serine ammonia-lyase activity
KK132_RS11155	COG0300	oxidoreductase activity
KK132_RS11160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KK132_RS11165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KK132_RS11170	COG1024	Enoyl-CoA hydratase
KK132_RS11175	COG3425	synthase
KK132_RS11180	COG2124	cytochrome p450
KK132_RS11185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS11185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KK132_RS11185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS11185	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS11185	COG3321	synthase
KK132_RS11190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KK132_RS11190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS11190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS11190	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS11190	COG3321	synthase
KK132_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS11195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS11195	COG3321	synthase
KK132_RS11195	COG0300	oxidoreductase activity
KK132_RS11195	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS11200	COG0300	oxidoreductase activity
KK132_RS11200	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS11200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS11200	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS11200	COG3321	synthase
KK132_RS11205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS11205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS11205	COG3321	synthase
KK132_RS11205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KK132_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS11210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS11210	COG0300	oxidoreductase activity
KK132_RS11210	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS11210	COG3321	synthase
KK132_RS11215	COG3321	synthase
KK132_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS11215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS11215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KK132_RS11215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK132_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS11225	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS11240	COG2070	2-Nitropropane dioxygenase
KK132_RS11240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KK132_RS11245	COG0250	Participates in transcription elongation, termination and antitermination
KK132_RS11265	COG0596	Alpha beta hydrolase
KK132_RS11280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KK132_RS11285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KK132_RS11300	COG0706	membrane insertase activity
KK132_RS11305	COG2195	Cleaves the N-terminal amino acid of tripeptides
KK132_RS11310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KK132_RS11315	COG0346	lactoylglutathione lyase activity
KK132_RS11330	COG4129	membrane
KK132_RS11335	COG1126	abc transporter atp-binding protein
KK132_RS11340	COG0765	amino acid transport
KK132_RS11345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK132_RS11355	COG1597	lipid kinase activity
KK132_RS11360	COG0508	dehydrogenase complex catalyzes the overall conversion of
KK132_RS11365	COG0022	dehydrogenase e1 component
KK132_RS11370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KK132_RS11375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KK132_RS11380	COG3426	butyrate kinase activity
KK132_RS11385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KK132_RS11390	COG0280	phosphate acetyltransferase
KK132_RS11395	COG3829	transcription factor binding
KK132_RS11395	COG3290	protein histidine kinase activity
KK132_RS11405	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KK132_RS11410	COG2079	MmgE PrpD family protein
KK132_RS11415	COG0372	Belongs to the citrate synthase family
KK132_RS11420	COG1960	acyl-CoA dehydrogenase activity
KK132_RS11425	COG1250	3-hydroxyacyl-CoA dehydrogenase
KK132_RS11430	COG0183	Belongs to the thiolase family
KK132_RS11435	COG0584	glycerophosphoryl diester phosphodiesterase
KK132_RS11440	COG0860	N-Acetylmuramoyl-L-alanine amidase
KK132_RS11465	COG1902	pentaerythritol trinitrate reductase activity
KK132_RS11480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KK132_RS11485	COG0745	RESPONSE REGULATOR receiver
KK132_RS11490	COG0750	zinc metalloprotease
KK132_RS11495	COG0497	DNA recombination
KK132_RS11505	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KK132_RS11515	COG0142	geranyltranstransferase activity
KK132_RS11525	COG1570	exodeoxyribonuclease VII activity
KK132_RS11540	COG1302	Protein conserved in bacteria
KK132_RS11545	COG0439	Biotin carboxylase
KK132_RS11550	COG0511	ligase activity, forming carbon-carbon bonds
KK132_RS11590	COG3854	ATPases associated with a variety of cellular activities
KK132_RS11605	COG0006	proline dipeptidase activity
KK132_RS11615	COG3872	metal-dependent enzyme
KK132_RS11625	COG1752	Esterase of the alpha-beta hydrolase superfamily
KK132_RS11640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KK132_RS11660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KK132_RS11675	COG1396	sequence-specific DNA binding
KK132_RS11685	COG0681	Belongs to the peptidase S26 family
KK132_RS11710	COG4940	Competence protein ComGF
KK132_RS11720	COG4970	Tfp pilus assembly protein FimT
KK132_RS11725	COG4537	Required for transformation and DNA binding
KK132_RS11730	COG1459	type II secretion system
KK132_RS11735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KK132_RS11740	COG0598	Magnesium transport protein CorA
KK132_RS11745	COG1253	flavin adenine dinucleotide binding
KK132_RS11750	COG1366	Belongs to the anti-sigma-factor antagonist family
KK132_RS11760	COG1393	Belongs to the ArsC family
KK132_RS11770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KK132_RS11780	COG0011	TIGRFAM Protein of
KK132_RS11790	COG2866	Carboxypeptidase
KK132_RS11795	COG1940	carbohydrate kinase activity
KK132_RS11800	COG4483	Protein conserved in bacteria
KK132_RS11805	COG1757	Na H antiporter
KK132_RS11815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KK132_RS11830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KK132_RS11835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KK132_RS11840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KK132_RS11845	COG0581	inorganic phosphate transmembrane transporter activity
KK132_RS11850	COG0573	inorganic phosphate transmembrane transporter activity
KK132_RS11855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KK132_RS11860	COG0768	penicillin binding
KK132_RS11865	COG0477	Major facilitator Superfamily
KK132_RS11870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KK132_RS11875	COG2839	Protein conserved in bacteria
KK132_RS11880	COG5521	maltodextrose utilization protein MalA
KK132_RS11885	COG1388	LysM domain
KK132_RS11895	COG4709	membrane
KK132_RS11900	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KK132_RS11905	COG0735	belongs to the Fur family
KK132_RS11910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KK132_RS11925	COG0513	Belongs to the DEAD box helicase family
KK132_RS11940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KK132_RS11945	COG2384	SAM-dependent methyltransferase
KK132_RS11950	COG2010	Cytochrome c
KK132_RS11955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KK132_RS11960	COG0358	DNA primase activity
KK132_RS11975	COG0517	IMP dehydrogenase activity
KK132_RS11980	COG0751	glycine-tRNA ligase activity
KK132_RS12000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KK132_RS12005	COG0295	cytidine deaminase activity
KK132_RS12010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KK132_RS12020	COG1480	7TM receptor with intracellular HD hydrolase
KK132_RS12025	COG1702	phosphate starvation-inducible protein PhoH
KK132_RS12030	COG0561	phosphatase activity
KK132_RS12045	COG4864	UPF0365 protein
KK132_RS12050	COG1030	water channel activity
KK132_RS12055	COG1610	YqeY-like protein
KK132_RS12065	COG1283	sodium-dependent phosphate transmembrane transporter activity
KK132_RS12070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KK132_RS12075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KK132_RS12105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KK132_RS12120	COG0860	N-Acetylmuramoyl-L-alanine amidase
KK132_RS12150	COG0658	competence protein
KK132_RS12150	COG2333	competence protein COMEC
KK132_RS12155	COG2131	deaminase
KK132_RS12160	COG1555	photosystem II stabilization
KK132_RS12160	COG1596	polysaccharide export
KK132_RS12165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KK132_RS12170	COG2226	methyltransferase
KK132_RS12175	COG0799	negative regulation of ribosome biogenesis
KK132_RS12180	COG1713	HD superfamily hydrolase involved in NAD metabolism
KK132_RS12190	COG1534	Rna-binding protein
KK132_RS12195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KK132_RS12200	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KK132_RS12205	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KK132_RS12220	COG2755	lipolytic protein G-D-S-L family
KK132_RS12230	COG0398	Pfam SNARE associated Golgi protein
KK132_RS12255	COG1794	racemase activity, acting on amino acids and derivatives
KK132_RS12275	COG0656	L-ascorbic acid biosynthetic process
KK132_RS12305	COG3677	Transposase
KK132_RS12345	COG5002	protein histidine kinase activity
KK132_RS12345	COG0642	Histidine kinase
KK132_RS12350	COG0745	RESPONSE REGULATOR receiver
KK132_RS12355	COG2311	Membrane
KK132_RS12365	COG0454	-acetyltransferase
KK132_RS12370	COG0563	adenylate kinase activity
KK132_RS12380	COG2814	Major facilitator Superfamily
KK132_RS12385	COG0456	acetyltransferase
KK132_RS12390	COG2318	DinB family
KK132_RS12400	COG0561	phosphatase activity
KK132_RS12405	COG0561	phosphatase activity
KK132_RS12415	COG1482	cell wall glycoprotein biosynthetic process
KK132_RS12420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK132_RS12420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KK132_RS12420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KK132_RS12425	COG3711	transcriptional antiterminator
KK132_RS12425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK132_RS12435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KK132_RS12440	COG0583	DNA-binding transcription factor activity
KK132_RS12445	COG2814	Major facilitator Superfamily
KK132_RS12450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KK132_RS12450	COG2124	cytochrome p450
KK132_RS12455	COG1309	transcriptional regulator
KK132_RS12460	COG2226	methyltransferase
KK132_RS12475	COG2116	formate transmembrane transporter activity
KK132_RS12480	COG5609	conserved protein (DUF2294)
KK132_RS12485	COG3383	formate dehydrogenase (NAD+) activity
KK132_RS12490	COG2427	Protein of unknown function (DUF1641)
KK132_RS12500	COG0626	cystathionine gamma-synthase activity
KK132_RS12505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KK132_RS12530	COG0768	penicillin binding
KK132_RS12545	COG0826	peptidase U32
KK132_RS12550	COG0826	peptidase U32
KK132_RS12555	COG4122	O-methyltransferase activity
KK132_RS12560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KK132_RS12585	COG0628	permease
KK132_RS12590	COG1126	abc transporter atp-binding protein
KK132_RS12595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK132_RS12600	COG0765	amino acid transport
KK132_RS12605	COG0765	amino acid transport
KK132_RS12620	COG3881	PFAM PRC-barrel domain
KK132_RS12625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KK132_RS12630	COG0457	Tetratricopeptide repeat
KK132_RS12640	COG1104	cysteine desulfurase activity
KK132_RS12645	COG1959	2 iron, 2 sulfur cluster binding
KK132_RS12650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KK132_RS12655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KK132_RS12680	COG3103	Sh3 type 3 domain protein
KK132_RS12680	COG0860	N-Acetylmuramoyl-L-alanine amidase
KK132_RS12680	COG4991	sh3 domain protein
KK132_RS12690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KK132_RS12700	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KK132_RS12700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KK132_RS12705	COG5416	Lipopolysaccharide assembly protein A domain
KK132_RS12710	COG0490	domain, Protein
KK132_RS12715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KK132_RS12715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KK132_RS12725	COG2244	polysaccharide biosynthetic process
KK132_RS12730	COG2323	membrane
KK132_RS12740	COG1862	Preprotein translocase
KK132_RS12780	COG1388	LysM domain
KK132_RS12790	COG0157	Belongs to the NadC ModD family
KK132_RS12795	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KK132_RS12800	COG1104	cysteine desulfurase activity
KK132_RS12805	COG1827	regulation of RNA biosynthetic process
KK132_RS12810	COG0077	Prephenate dehydratase
KK132_RS12825	COG3290	protein histidine kinase activity
KK132_RS12830	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KK132_RS12835	COG2868	ribosomal protein
KK132_RS12845	COG1994	Peptidase M50
KK132_RS12850	COG0739	heme binding
KK132_RS12855	COG2894	cell division
KK132_RS12860	COG0850	regulation of cytokinetic process
KK132_RS12865	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KK132_RS12875	COG1077	Cell shape determining protein MreB Mrl
KK132_RS12895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KK132_RS12900	COG0285	dihydrofolate synthase activity
KK132_RS12905	COG0525	valine-tRNA ligase activity
KK132_RS12915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KK132_RS12920	COG1388	LysM domain
KK132_RS12930	COG0113	porphobilinogen synthase activity
KK132_RS12935	COG1587	Uroporphyrinogen-III synthase
KK132_RS12945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KK132_RS12965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KK132_RS12970	COG0470	DNA polymerase III
KK132_RS12970	COG1067	ATP-dependent peptidase activity
KK132_RS12985	COG0457	Tetratricopeptide repeat
KK132_RS12985	COG1477	protein flavinylation
KK132_RS13000	COG0473	3-isopropylmalate dehydrogenase activity
KK132_RS13015	COG0440	acetolactate synthase activity
KK132_RS13020	COG0028	Belongs to the TPP enzyme family
KK132_RS13045	COG0622	Phosphoesterase
KK132_RS13050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KK132_RS13060	COG5401	PFAM Sporulation and spore germination
KK132_RS13070	COG1846	Transcriptional regulator
KK132_RS13075	COG2197	response regulator
KK132_RS13080	COG0824	Thioesterase
KK132_RS13085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KK132_RS13090	COG1053	succinate dehydrogenase
KK132_RS13095	COG2009	succinate dehydrogenase
KK132_RS13100	COG1719	4-vinyl reductase, 4VR
KK132_RS13105	COG0527	aspartate kinase activity
KK132_RS13115	COG3118	belongs to the thioredoxin family
KK132_RS13120	COG3534	alpha-L-arabinofuranosidase
KK132_RS13125	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KK132_RS13130	COG2086	electron transfer activity
KK132_RS13135	COG1024	Enoyl-CoA hydratase
KK132_RS13140	COG1309	transcriptional regulator
KK132_RS13145	COG0318	PFAM AMP-dependent synthetase and ligase
KK132_RS13155	COG3766	membrane
KK132_RS13165	COG1796	DNA polymerase
KK132_RS13165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KK132_RS13170	COG1286	toxin biosynthetic process
KK132_RS13185	COG0072	phenylalanine-tRNA ligase activity
KK132_RS13185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KK132_RS13190	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KK132_RS13195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KK132_RS13205	COG3835	regulator
KK132_RS13210	COG0277	FAD linked oxidase domain protein
KK132_RS13215	COG0247	lactate metabolic process
KK132_RS13220	COG1966	Carbon starvation protein
KK132_RS13225	COG3534	alpha-L-arabinofuranosidase
KK132_RS13230	COG0395	ABC-type sugar transport system, permease component
KK132_RS13235	COG1175	transmembrane transport
KK132_RS13240	COG1653	transport
KK132_RS13250	COG0647	UMP catabolic process
KK132_RS13255	COG0235	Class ii aldolase
KK132_RS13260	COG1069	ribulokinase activity
KK132_RS13265	COG2160	L-arabinose isomerase activity
KK132_RS13270	COG3507	Belongs to the glycosyl hydrolase 43 family
KK132_RS13275	COG1363	Peptidase, m42
KK132_RS13285	COG3326	Membrane
KK132_RS13300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KK132_RS13305	COG1346	cytolysis
KK132_RS13310	COG1380	Effector of murein hydrolase LrgA
KK132_RS13315	COG3279	Response regulator of the LytR AlgR family
KK132_RS13320	COG3275	phosphorelay sensor kinase activity
KK132_RS13325	COG1011	Hydrolase
KK132_RS13340	COG0398	Pfam SNARE associated Golgi protein
KK132_RS13345	COG1484	DNA-dependent DNA replication
KK132_RS13350	COG3611	Membrane attachment protein
KK132_RS13365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KK132_RS13370	COG1733	regulation of RNA biosynthetic process
KK132_RS13375	COG2814	Major facilitator Superfamily
KK132_RS13380	COG0656	L-ascorbic acid biosynthetic process
KK132_RS13385	COG0237	dephospho-CoA kinase activity
KK132_RS13390	COG1971	Probably functions as a manganese efflux pump
KK132_RS13395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KK132_RS13400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KK132_RS13400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KK132_RS13405	COG5002	protein histidine kinase activity
KK132_RS13410	COG0745	RESPONSE REGULATOR receiver
KK132_RS13420	COG0538	isocitrate dehydrogenase activity
KK132_RS13425	COG0372	Belongs to the citrate synthase family
KK132_RS13455	COG0628	permease
KK132_RS13460	COG3030	protein affecting phage T7 exclusion by the F plasmid
KK132_RS13465	COG0469	pyruvate kinase activity
KK132_RS13485	COG0281	malic enzyme
KK132_RS13490	COG0587	DNA-directed DNA polymerase activity
KK132_RS13510	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KK132_RS13520	COG4109	DRTGG domain
KK132_RS13530	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS13550	COG0521	Mo-molybdopterin cofactor biosynthetic process
KK132_RS13560	COG0827	DNA restriction-modification system
KK132_RS13565	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KK132_RS13570	COG3874	Sporulation protein YtfJ
KK132_RS13580	COG1714	RDD family
KK132_RS13585	COG0616	signal peptide processing
KK132_RS13590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KK132_RS13595	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KK132_RS13600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KK132_RS13615	COG1104	cysteine desulfurase activity
KK132_RS13620	COG1114	Component of the transport system for branched-chain amino acids
KK132_RS13630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KK132_RS13635	COG1309	transcriptional regulator
KK132_RS13640	COG1956	GAF domain-containing protein
KK132_RS13645	COG2203	Gaf domain
KK132_RS13645	COG2199	diguanylate cyclase activity
KK132_RS13655	COG1012	belongs to the aldehyde dehydrogenase family
KK132_RS13660	COG4282	regulation of fungal-type cell wall biogenesis
KK132_RS13705	COG1017	nitric oxide dioxygenase activity
KK132_RS13705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KK132_RS13715	COG0693	protein deglycase activity
KK132_RS13735	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KK132_RS13740	COG1378	Sugar-specific transcriptional regulator TrmB
KK132_RS13765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KK132_RS13770	COG0454	-acetyltransferase
KK132_RS13775	COG0517	IMP dehydrogenase activity
KK132_RS13780	COG0123	including yeast histone deacetylase and acetoin utilization protein
KK132_RS13785	COG1360	Flagellar Motor Protein
KK132_RS13790	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KK132_RS13795	COG1609	Transcriptional regulator
KK132_RS13800	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KK132_RS13800	COG1605	Chorismate mutase
KK132_RS13805	COG3118	belongs to the thioredoxin family
KK132_RS13810	COG4980	gas vesicle protein
KK132_RS13815	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KK132_RS13825	COG1674	ftsk spoiiie
KK132_RS13830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KK132_RS13840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK132_RS13850	COG1363	Peptidase, m42
KK132_RS13855	COG5584	Small secreted protein
KK132_RS13860	COG0281	malic enzyme
KK132_RS13865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KK132_RS13880	COG0510	thiamine kinase activity
KK132_RS13885	COG1597	lipid kinase activity
KK132_RS13895	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KK132_RS13900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KK132_RS13905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KK132_RS13910	COG2252	PERMEase
KK132_RS13915	COG4473	ABC transporter
KK132_RS13920	COG1131	(ABC) transporter
KK132_RS13925	COG1349	DNA-binding transcription factor activity
KK132_RS13930	COG1187	pseudouridine synthase activity
KK132_RS13935	COG2244	polysaccharide biosynthetic process
KK132_RS13940	COG2081	HI0933 family
KK132_RS13945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KK132_RS13955	COG1609	Transcriptional regulator
KK132_RS13960	COG1653	transport
KK132_RS13965	COG1175	transmembrane transport
KK132_RS13970	COG0395	ABC-type sugar transport system, permease component
KK132_RS13975	COG1486	melibiose metabolic process
KK132_RS13985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KK132_RS14000	COG2202	Pas domain
KK132_RS14000	COG1366	Belongs to the anti-sigma-factor antagonist family
KK132_RS14005	COG2814	Major facilitator Superfamily
KK132_RS14010	COG5522	Integral membrane protein (intg_mem_TP0381)
KK132_RS14015	COG0577	efflux transmembrane transporter activity
KK132_RS14020	COG1136	(ABC) transporter
KK132_RS14025	COG2205	protein histidine kinase activity
KK132_RS14030	COG0745	RESPONSE REGULATOR receiver
KK132_RS14035	COG0577	efflux transmembrane transporter activity
KK132_RS14040	COG1136	(ABC) transporter
KK132_RS14060	COG1131	(ABC) transporter
KK132_RS14065	COG1725	Transcriptional regulator
KK132_RS14080	COG1242	4 iron, 4 sulfur cluster binding
KK132_RS14085	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KK132_RS14095	COG0584	glycerophosphoryl diester phosphodiesterase
KK132_RS14105	COG2267	carboxylic ester hydrolase activity
KK132_RS14110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KK132_RS14115	COG1113	amino acid transport
KK132_RS14120	COG0367	asparagine synthase
KK132_RS14140	COG1506	peptidase
KK132_RS14145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KK132_RS14150	COG1116	anion transmembrane transporter activity
KK132_RS14155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KK132_RS14160	COG0494	nUDIX hydrolase
KK132_RS14165	COG4824	toxin secretion phage lysis holin
KK132_RS14170	COG0783	Belongs to the Dps family
KK132_RS14195	COG0288	reversible hydration of carbon dioxide
KK132_RS14205	COG1271	oxidase subunit
KK132_RS14210	COG1294	oxidase, subunit
KK132_RS14225	COG4948	Mandelate Racemase Muconate Lactonizing
KK132_RS14235	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KK132_RS14240	COG0596	Alpha beta hydrolase
KK132_RS14250	COG1169	isochorismate synthase
KK132_RS14255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KK132_RS14260	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KK132_RS14385	COG3859	Proton-coupled thiamine transporter YuaJ
KK132_RS14390	COG2268	Band 7 protein
KK132_RS14395	COG1585	Membrane protein implicated in regulation of membrane protease activity
KK132_RS14400	COG2318	DinB family
KK132_RS14410	COG1454	alcohol dehydrogenase
KK132_RS14415	COG1012	belongs to the aldehyde dehydrogenase family
KK132_RS14420	COG1510	regulation of RNA biosynthetic process
KK132_RS14430	COG0569	domain protein
KK132_RS14435	COG1705	Flagellar rod assembly protein muramidase FlgJ
KK132_RS14440	COG1017	nitric oxide dioxygenase activity
KK132_RS14440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KK132_RS14465	COG0628	permease
KK132_RS14470	COG0673	inositol 2-dehydrogenase activity
KK132_RS14475	COG0693	protein deglycase activity
KK132_RS14480	COG0840	transmembrane signaling receptor activity
KK132_RS14485	COG0840	transmembrane signaling receptor activity
KK132_RS14490	COG0840	transmembrane signaling receptor activity
KK132_RS14495	COG0840	transmembrane signaling receptor activity
KK132_RS14510	COG2070	2-Nitropropane dioxygenase
KK132_RS14515	COG0432	Pfam Uncharacterised protein family UPF0047
KK132_RS14520	COG0366	Alpha amylase catalytic
KK132_RS14525	COG1253	flavin adenine dinucleotide binding
KK132_RS14530	COG2738	Putative neutral zinc metallopeptidase
KK132_RS14545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KK132_RS14570	COG1335	isochorismatase
KK132_RS14575	COG1979	alcohol dehydrogenase
KK132_RS14580	COG1979	alcohol dehydrogenase
KK132_RS14585	COG2155	Conserved Protein
KK132_RS14590	COG1098	S1 RNA binding domain
KK132_RS14595	COG0436	Aminotransferase
KK132_RS14600	COG1522	sequence-specific DNA binding
KK132_RS14605	COG2267	carboxylic ester hydrolase activity
KK132_RS14615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KK132_RS14620	COG2205	protein histidine kinase activity
KK132_RS14630	COG5018	Exonuclease
KK132_RS14635	COG2814	Major facilitator Superfamily
KK132_RS14640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KK132_RS14645	COG3011	Protein conserved in bacteria
KK132_RS14655	COG3290	protein histidine kinase activity
KK132_RS14660	COG4565	transcriptional regulatory protein
KK132_RS14665	COG1744	ABC transporter substrate-binding protein PnrA-like
KK132_RS14670	COG3845	ABC transporter
KK132_RS14675	COG4603	Belongs to the binding-protein-dependent transport system permease family
KK132_RS14680	COG1079	Belongs to the binding-protein-dependent transport system permease family
KK132_RS14690	COG2111	Na H antiporter
KK132_RS14690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KK132_RS14695	COG2111	Na H antiporter
KK132_RS14700	COG1006	Multisubunit Na H antiporter MnhC subunit
KK132_RS14705	COG0651	ATP synthesis coupled electron transport
KK132_RS14710	COG1863	multisubunit Na H antiporter MnhE subunit
KK132_RS14715	COG2212	antiporter activity
KK132_RS14720	COG1320	monovalent cation:proton antiporter activity
KK132_RS14725	COG2050	protein possibly involved in aromatic compounds catabolism
KK132_RS14730	COG2197	response regulator
KK132_RS14735	COG4585	Histidine kinase
KK132_RS14760	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KK132_RS14765	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KK132_RS14770	COG1335	isochorismatase
KK132_RS14775	COG5506	Protein of unknown function (DUF1694)
KK132_RS14790	COG0628	permease
KK132_RS14800	COG1418	mRNA catabolic process
KK132_RS14805	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS14815	COG1511	domain protein
KK132_RS14820	COG0433	COG0433 Predicted ATPase
KK132_RS14820	COG1674	ftsk spoiiie
KK132_RS14825	COG4499	WXG100 protein secretion system (Wss), protein YukC
KK132_RS14830	COG5417	Belongs to the EsaB family
KK132_RS14835	COG4842	Belongs to the WXG100 family
KK132_RS14840	COG2508	Transcriptional regulator
KK132_RS14840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KK132_RS14845	COG0686	Belongs to the AlaDH PNT family
KK132_RS14850	COG5634	Uncharacterized conserved protein (DUF2278)
KK132_RS14855	COG3251	PFAM MbtH domain protein
KK132_RS14860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KK132_RS14865	COG1535	isochorismatase
KK132_RS14865	COG3433	isochorismatase activity
KK132_RS14870	COG1021	2,3-dihydroxybenzoate-AMP ligase
KK132_RS14875	COG1169	isochorismate synthase
KK132_RS14880	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS14885	COG2819	hydrolase of the alpha beta superfamily
KK132_RS14890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KK132_RS14895	COG1268	BioY protein
KK132_RS14900	COG2056	Na+-H+ antiporter family
KK132_RS14910	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KK132_RS14915	COG3584	3D domain protein
KK132_RS14930	COG1252	NADH dehydrogenase
KK132_RS14960	COG1131	(ABC) transporter
KK132_RS14980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KK132_RS14985	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KK132_RS14990	COG0316	Belongs to the HesB IscA family
KK132_RS15000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KK132_RS15010	COG1252	NADH dehydrogenase
KK132_RS15015	COG4837	Protein of unknown function (DUF1462)
KK132_RS15020	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KK132_RS15025	COG4946	Tricorn protease homolog
KK132_RS15025	COG1506	peptidase
KK132_RS15025	COG0823	Involved in the tonB-independent uptake of proteins
KK132_RS15035	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KK132_RS15040	COG0460	homoserine dehydrogenase
KK132_RS15045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KK132_RS15050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KK132_RS15055	COG0647	UMP catabolic process
KK132_RS15060	COG2445	Protein of unknown function DUF86
KK132_RS15065	COG4470	Protein conserved in bacteria
KK132_RS15075	COG0739	heme binding
KK132_RS15085	COG0737	Belongs to the 5'-nucleotidase family
KK132_RS15090	COG0730	response to heat
KK132_RS15095	COG1801	Protein of unknown function DUF72
KK132_RS15110	COG2508	Transcriptional regulator
KK132_RS15135	COG2814	Major facilitator Superfamily
KK132_RS15140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KK132_RS15145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KK132_RS15150	COG2356	endonuclease I
KK132_RS15155	COG3842	ATPase activity
KK132_RS15160	COG2188	Transcriptional regulator
KK132_RS15165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KK132_RS15170	COG0395	ABC-type sugar transport system, permease component
KK132_RS15175	COG1175	transmembrane transport
KK132_RS15180	COG1653	transport
KK132_RS15185	COG2222	sugar isomerase
KK132_RS15190	COG0789	Transcriptional regulator
KK132_RS15215	COG0322	excinuclease ABC activity
KK132_RS15220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KK132_RS15240	COG3409	Peptidoglycan-binding domain 1 protein
KK132_RS15245	COG0719	Fe-S assembly protein
KK132_RS15250	COG0822	iron-sulfur transferase activity
KK132_RS15255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KK132_RS15260	COG0719	Fe-S assembly protein
KK132_RS15265	COG0396	ATPase activity
KK132_RS15275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KK132_RS15280	COG1464	Belongs to the NlpA lipoprotein family
KK132_RS15285	COG2011	ABC-type metal ion transport system permease component
KK132_RS15290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KK132_RS15300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK132_RS15305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KK132_RS15320	COG1393	Belongs to the ArsC family
KK132_RS15325	COG1960	acyl-CoA dehydrogenase activity
KK132_RS15330	COG0183	Belongs to the thiolase family
KK132_RS15335	COG1250	3-hydroxyacyl-CoA dehydrogenase
KK132_RS15335	COG1024	Enoyl-CoA hydratase
KK132_RS15355	COG5577	PFAM Coat F domain
KK132_RS15360	COG1846	Transcriptional regulator
KK132_RS15365	COG0477	Major facilitator Superfamily
KK132_RS15370	COG1942	4-Oxalocrotonate Tautomerase
KK132_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS15380	COG0583	DNA-binding transcription factor activity
KK132_RS15390	COG0583	DNA-binding transcription factor activity
KK132_RS15410	COG1120	ATPase activity
KK132_RS15425	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS15430	COG0783	Belongs to the Dps family
KK132_RS15435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KK132_RS15440	COG0745	RESPONSE REGULATOR receiver
KK132_RS15445	COG2205	protein histidine kinase activity
KK132_RS15445	COG2770	Histidine kinase
KK132_RS15455	COG1309	transcriptional regulator
KK132_RS15460	COG0114	fumarate hydratase activity
KK132_RS15470	COG0697	spore germination
KK132_RS15475	COG0814	amino acid
KK132_RS15485	COG2197	response regulator
KK132_RS15490	COG4585	Histidine kinase
KK132_RS15495	COG4758	membrane
KK132_RS15500	COG3595	metallopeptidase activity
KK132_RS15505	COG1842	Phage shock protein A
KK132_RS15510	COG4758	membrane
KK132_RS15515	COG2814	Major facilitator Superfamily
KK132_RS15520	COG2096	Adenosyltransferase
KK132_RS15525	COG1120	ATPase activity
KK132_RS15530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK132_RS15535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KK132_RS15540	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS15545	COG3386	PFAM SMP-30 Gluconolaconase
KK132_RS15550	COG2205	protein histidine kinase activity
KK132_RS15555	COG0745	RESPONSE REGULATOR receiver
KK132_RS15565	COG1191	sigma factor activity
KK132_RS15575	COG2140	Oxalate decarboxylase
KK132_RS15585	COG1120	ATPase activity
KK132_RS15590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK132_RS15595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK132_RS15600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KK132_RS15605	COG0531	amino acid
KK132_RS15615	COG1988	membrane-bound metal-dependent
KK132_RS15620	COG1368	sulfuric ester hydrolase activity
KK132_RS15625	COG1910	domain protein
KK132_RS15630	COG0725	ABC transporter, periplasmic molybdate-binding protein
KK132_RS15635	COG4149	molybdate abc transporter
KK132_RS15640	COG2197	response regulator
KK132_RS15645	COG3850	Histidine kinase
KK132_RS15650	COG1131	(ABC) transporter
KK132_RS15660	COG0842	Transport permease protein
KK132_RS15665	COG0656	L-ascorbic acid biosynthetic process
KK132_RS15685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KK132_RS15690	COG3973	AAA domain
KK132_RS15695	COG2860	membrane
KK132_RS15705	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KK132_RS15710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KK132_RS15715	COG2217	Heavy metal translocating P-type atpase
KK132_RS15720	COG2217	Heavy metal translocating P-type atpase
KK132_RS15725	COG2608	mercury ion transmembrane transporter activity
KK132_RS15730	COG1937	Protein conserved in bacteria
KK132_RS15735	COG0673	inositol 2-dehydrogenase activity
KK132_RS15745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KK132_RS15750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KK132_RS15755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KK132_RS15760	COG1126	abc transporter atp-binding protein
KK132_RS15765	COG0765	amino acid transport
KK132_RS15770	COG0765	amino acid transport
KK132_RS15775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK132_RS15780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK132_RS15785	COG0454	-acetyltransferase
KK132_RS15790	COG0583	DNA-binding transcription factor activity
KK132_RS15795	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS15840	COG0557	exoribonuclease II activity
KK132_RS15845	COG1647	Serine aminopeptidase, S33
KK132_RS15850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KK132_RS15855	COG1476	TRANSCRIPTIONal
KK132_RS15860	COG1396	sequence-specific DNA binding
KK132_RS15865	COG1396	sequence-specific DNA binding
KK132_RS15870	COG1733	regulation of RNA biosynthetic process
KK132_RS15895	COG1131	(ABC) transporter
KK132_RS15900	COG1174	glycine betaine transport
KK132_RS15905	COG1732	Glycine betaine
KK132_RS15910	COG1174	glycine betaine transport
KK132_RS15915	COG1125	glycine betaine transport
KK132_RS15915	COG0517	IMP dehydrogenase activity
KK132_RS15920	COG1510	regulation of RNA biosynthetic process
KK132_RS15925	COG1174	glycine betaine transport
KK132_RS15930	COG1732	Glycine betaine
KK132_RS15935	COG1174	glycine betaine transport
KK132_RS15940	COG1125	glycine betaine transport
KK132_RS15940	COG0517	IMP dehydrogenase activity
KK132_RS15945	COG1510	regulation of RNA biosynthetic process
KK132_RS15950	COG2095	MarC family integral membrane protein
KK132_RS15955	COG3064	Membrane
KK132_RS15960	COG4640	response to antibiotic
KK132_RS15965	COG0456	acetyltransferase
KK132_RS15980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KK132_RS16000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KK132_RS16005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KK132_RS16015	COG2234	aminopeptidase activity
KK132_RS16035	COG0126	phosphoglycerate kinase activity
KK132_RS16040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KK132_RS16045	COG2390	Transcriptional regulator
KK132_RS16050	COG2814	Major facilitator Superfamily
KK132_RS16055	COG1609	Transcriptional regulator
KK132_RS16060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KK132_RS16070	COG0583	DNA-binding transcription factor activity
KK132_RS16075	COG0697	spore germination
KK132_RS16080	COG1113	amino acid transport
KK132_RS16085	COG1609	Transcriptional regulator
KK132_RS16095	COG0561	phosphatase activity
KK132_RS16100	COG1737	Transcriptional regulator
KK132_RS16105	COG1070	Carbohydrate kinase
KK132_RS16145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KK132_RS16150	COG2186	Transcriptional regulator
KK132_RS16155	COG1620	l-lactate permease
KK132_RS16160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KK132_RS16170	COG5039	Polysaccharide pyruvyl transferase
KK132_RS16175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KK132_RS16180	COG0110	maltose O-acetyltransferase activity
KK132_RS16185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KK132_RS16190	COG2244	polysaccharide biosynthetic process
KK132_RS16195	COG1216	Glycosyl transferase, family 2
KK132_RS16200	COG5039	Polysaccharide pyruvyl transferase
KK132_RS16205	COG1216	Glycosyl transferase, family 2
KK132_RS16215	COG0438	transferase activity, transferring glycosyl groups
KK132_RS16220	COG1215	transferase activity, transferring glycosyl groups
KK132_RS16225	COG0438	transferase activity, transferring glycosyl groups
KK132_RS16230	COG1086	Polysaccharide biosynthesis protein
KK132_RS16235	COG0489	protein tyrosine kinase activity
KK132_RS16240	COG3944	biosynthesis protein
KK132_RS16245	COG1396	sequence-specific DNA binding
KK132_RS16250	COG2272	Belongs to the type-B carboxylesterase lipase family
KK132_RS16255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KK132_RS16260	COG2364	Membrane
KK132_RS16265	COG0456	acetyltransferase
KK132_RS16270	COG3479	Phenolic acid decarboxylase
KK132_RS16325	COG2223	nitrite transmembrane transporter activity
KK132_RS16330	COG1609	Transcriptional regulator
KK132_RS16340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KK132_RS16345	COG0366	Alpha amylase catalytic
KK132_RS16350	COG1554	hydrolase, family 65, central catalytic
KK132_RS16355	COG5521	maltodextrose utilization protein MalA
KK132_RS16360	COG3833	ABC-type maltose transport systems, permease component
KK132_RS16365	COG1175	transmembrane transport
KK132_RS16370	COG2182	Extracellular solute-binding protein
KK132_RS16375	COG0366	Alpha amylase catalytic
KK132_RS16380	COG1609	Transcriptional regulator
KK132_RS16385	COG1611	Belongs to the LOG family
KK132_RS16390	COG1694	Mazg nucleotide pyrophosphohydrolase
KK132_RS16395	COG0659	secondary active sulfate transmembrane transporter activity
KK132_RS16400	COG0288	reversible hydration of carbon dioxide
KK132_RS16405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KK132_RS16410	COG4290	ribonuclease
KK132_RS16415	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KK132_RS16420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK132_RS16430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KK132_RS16440	COG1051	belongs to the nudix hydrolase family
KK132_RS16445	COG0492	ferredoxin-NADP+ reductase activity
KK132_RS16450	COG0791	NLP P60 protein
KK132_RS16450	COG3883	PFAM NLP P60 protein
KK132_RS16455	COG0457	Tetratricopeptide repeat
KK132_RS16460	COG5002	protein histidine kinase activity
KK132_RS16465	COG0745	RESPONSE REGULATOR receiver
KK132_RS16470	COG1132	(ABC) transporter
KK132_RS16475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KK132_RS16475	COG0140	phosphoribosyl-ATP diphosphatase activity
KK132_RS16500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KK132_RS16515	COG4990	cell redox homeostasis
KK132_RS16520	COG0110	maltose O-acetyltransferase activity
KK132_RS16540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KK132_RS16550	COG2188	Transcriptional regulator
KK132_RS16555	COG1309	transcriptional regulator
KK132_RS16560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KK132_RS16565	COG1950	PFAM Membrane protein of
KK132_RS16570	COG1983	PspC domain protein
KK132_RS16575	COG3595	metallopeptidase activity
KK132_RS16590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KK132_RS16600	COG4897	Protein conserved in bacteria
KK132_RS16605	COG3848	Pyruvate phosphate dikinase
KK132_RS16605	COG0574	Belongs to the PEP-utilizing enzyme family
KK132_RS16610	COG1309	transcriptional regulator
KK132_RS16615	COG2814	Major facilitator Superfamily
KK132_RS16630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KK132_RS16640	COG0793	Belongs to the peptidase S41A family
KK132_RS16640	COG3409	Peptidoglycan-binding domain 1 protein
KK132_RS16645	COG3420	alginic acid biosynthetic process
KK132_RS16650	COG2177	Part of the ABC transporter FtsEX involved in
KK132_RS16655	COG2884	Cell division ATP-binding protein ftsE
KK132_RS16660	COG2010	Cytochrome c
KK132_RS16665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KK132_RS16680	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KK132_RS16695	COG1516	flagellar protein fliS
KK132_RS16700	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KK132_RS16705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KK132_RS16725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KK132_RS16730	COG1256	bacterial-type flagellum assembly
KK132_RS16730	COG4786	Flagellar basal body rod
KK132_RS16735	COG3418	PFAM FlgN family protein
KK132_RS16740	COG2747	anti-sigma28 factor FlgM
KK132_RS16750	COG1040	competence protein
KK132_RS16760	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KK132_RS16765	COG1307	EDD domain protein, DegV family
KK132_RS16770	COG2197	response regulator
KK132_RS16775	COG4585	Histidine kinase
KK132_RS16780	COG1739	Uncharacterized protein family UPF0029
KK132_RS16785	COG1316	TRANSCRIPTIONal
KK132_RS16790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KK132_RS16795	COG0438	transferase activity, transferring glycosyl groups
KK132_RS16800	COG1215	transferase activity, transferring glycosyl groups
KK132_RS16805	COG3206	protein involved in exopolysaccharide biosynthesis
KK132_RS16810	COG3307	-O-antigen
KK132_RS16815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KK132_RS16820	COG0438	transferase activity, transferring glycosyl groups
KK132_RS16820	COG0297	glycogen (starch) synthase activity
KK132_RS16825	COG2244	polysaccharide biosynthetic process
KK132_RS16835	COG2247	cell wall binding repeat
KK132_RS16835	COG0860	N-Acetylmuramoyl-L-alanine amidase
KK132_RS16840	COG2247	cell wall binding repeat
KK132_RS16840	COG2385	sporulation resulting in formation of a cellular spore
KK132_RS16850	COG1316	TRANSCRIPTIONal
KK132_RS16855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KK132_RS16860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KK132_RS16865	COG1134	teichoic acid transport
KK132_RS16870	COG1682	transport, permease protein
KK132_RS16875	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KK132_RS16885	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KK132_RS16890	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KK132_RS16895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KK132_RS16900	COG4193	domain, Protein
KK132_RS16905	COG1482	cell wall glycoprotein biosynthetic process
KK132_RS16910	COG0697	spore germination
KK132_RS16915	COG0814	amino acid
KK132_RS16925	COG1215	transferase activity, transferring glycosyl groups
KK132_RS16930	COG2814	Major facilitator Superfamily
KK132_RS16935	COG1316	TRANSCRIPTIONal
KK132_RS16940	COG0561	phosphatase activity
KK132_RS16945	COG2433	Pfam Transposase IS66
KK132_RS16950	COG0791	NLP P60 protein
KK132_RS16960	COG2843	Capsule synthesis protein
KK132_RS16970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KK132_RS16975	COG0697	spore germination
KK132_RS16980	COG0814	amino acid
KK132_RS16990	COG1609	Transcriptional regulator
KK132_RS16995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KK132_RS17005	COG1129	ABC transporter
KK132_RS17010	COG1172	Belongs to the binding-protein-dependent transport system permease family
KK132_RS17015	COG1879	ABC-type sugar transport system periplasmic component
KK132_RS17020	COG3103	Sh3 type 3 domain protein
KK132_RS17025	COG2249	NAD(P)H dehydrogenase (quinone) activity
KK132_RS17030	COG3527	Alpha-acetolactate decarboxylase
KK132_RS17035	COG0028	Belongs to the TPP enzyme family
KK132_RS17040	COG0583	DNA-binding transcription factor activity
KK132_RS17045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KK132_RS17060	COG5337	Spore coat protein CotH
KK132_RS17070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KK132_RS17080	COG0405	Gamma-glutamyltransferase
KK132_RS17085	COG1522	sequence-specific DNA binding
KK132_RS17090	COG2059	Chromate
KK132_RS17095	COG2059	Chromate
KK132_RS17105	COG0655	NAD(P)H dehydrogenase (quinone) activity
KK132_RS17110	COG0583	DNA-binding transcription factor activity
KK132_RS17140	COG5444	nuclease activity
KK132_RS17155	COG3878	Protein conserved in bacteria
KK132_RS17160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KK132_RS17165	COG4464	protein tyrosine phosphatase activity
KK132_RS17170	COG0489	protein tyrosine kinase activity
KK132_RS17175	COG3944	biosynthesis protein
KK132_RS17185	COG4715	Zinc finger, swim domain protein
KK132_RS17190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KK132_RS17195	COG0561	phosphatase activity
KK132_RS17200	COG1349	DNA-binding transcription factor activity
KK132_RS17205	COG0629	single-stranded DNA binding
KK132_RS17230	COG0457	Tetratricopeptide repeat
KK132_RS17235	COG4786	Flagellar basal body rod
KK132_RS17240	COG4786	Flagellar basal body rod
KK132_RS17245	COG1077	Cell shape determining protein MreB Mrl
KK132_RS17250	COG1609	Transcriptional regulator
KK132_RS17255	COG1846	Transcriptional regulator
KK132_RS17260	COG2814	Major facilitator Superfamily
KK132_RS17265	COG1953	Uracil, thiamine, allantoin
KK132_RS17270	COG0477	Major facilitator Superfamily
KK132_RS17275	COG1335	isochorismatase
KK132_RS17280	COG0004	ammonium transporteR
KK132_RS17285	COG0347	Belongs to the P(II) protein family
KK132_RS17290	COG0772	Belongs to the SEDS family
KK132_RS17295	COG0671	phosphoesterase, PA-phosphatase related
KK132_RS17305	COG0739	heme binding
KK132_RS17310	COG1247	-acetyltransferase
KK132_RS17325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KK132_RS17340	COG0726	polysaccharide deacetylase
KK132_RS17350	COG1959	2 iron, 2 sulfur cluster binding
KK132_RS17365	COG0831	urea catabolic process
KK132_RS17370	COG3237	CsbD-like
KK132_RS17375	COG1994	Peptidase M50
KK132_RS17380	COG0457	Tetratricopeptide repeat
KK132_RS17390	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KK132_RS17400	COG2304	oxidoreductase activity
KK132_RS17405	COG2304	oxidoreductase activity
KK132_RS17410	COG2385	sporulation resulting in formation of a cellular spore
KK132_RS17415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KK132_RS17425	COG4836	Membrane
KK132_RS17495	COG0698	ribose 5-phosphate isomerase
KK132_RS17500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KK132_RS17510	COG0009	L-threonylcarbamoyladenylate synthase
KK132_RS17515	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KK132_RS17535	COG2890	protein-(glutamine-N5) methyltransferase activity
KK132_RS17540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KK132_RS17545	COG0346	lactoylglutathione lyase activity
KK132_RS17550	COG0789	Transcriptional regulator
KK132_RS17555	COG0679	Auxin Efflux Carrier
KK132_RS17560	COG0281	malic enzyme
KK132_RS17575	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KK132_RS17585	COG1494	fructose-1,6-bisphosphatase
KK132_RS17590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KK132_RS17600	COG0191	fructose-bisphosphate aldolase activity
KK132_RS17605	COG2204	response regulator
KK132_RS17610	COG4821	SIS domain
KK132_RS17625	COG0247	lactate metabolic process
KK132_RS17625	COG2181	nitrate reductase activity
KK132_RS17630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KK132_RS17645	COG1132	(ABC) transporter
KK132_RS17650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KK132_RS17660	COG2181	nitrate reductase activity
KK132_RS17665	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KK132_RS17670	COG1140	nitrate reductase beta subunit
KK132_RS17675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KK132_RS17680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KK132_RS17690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KK132_RS17695	COG2223	nitrite transmembrane transporter activity
KK132_RS17705	COG4506	Protein conserved in bacteria
KK132_RS17715	COG3391	amine dehydrogenase activity
KK132_RS17720	COG3391	amine dehydrogenase activity
KK132_RS17725	COG0457	Tetratricopeptide repeat
KK132_RS17735	COG0010	Belongs to the arginase family
KK132_RS17740	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KK132_RS17745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KK132_RS17760	COG1994	Peptidase M50
KK132_RS17765	COG1942	4-Oxalocrotonate Tautomerase
KK132_RS17770	COG1846	Transcriptional regulator
KK132_RS17775	COG0531	amino acid
KK132_RS17780	COG3465	dGTPase activity
KK132_RS17785	COG1078	dGTPase activity
KK132_RS17800	COG1695	Transcriptional regulator
KK132_RS17810	COG1131	(ABC) transporter
KK132_RS17815	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KK132_RS17845	COG0583	DNA-binding transcription factor activity
KK132_RS17850	COG2855	membrane
KK132_RS17855	COG0280	phosphate acetyltransferase
KK132_RS17865	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS17870	COG0436	Aminotransferase
KK132_RS17900	COG2814	Major facilitator Superfamily
KK132_RS17905	COG2814	Major facilitator Superfamily
KK132_RS17910	COG0833	amino acid
KK132_RS17915	COG4187	Peptidase family M20/M25/M40
KK132_RS17920	COG1012	belongs to the aldehyde dehydrogenase family
KK132_RS17925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KK132_RS17930	COG2205	protein histidine kinase activity
KK132_RS17935	COG0745	RESPONSE REGULATOR receiver
KK132_RS17950	COG1131	(ABC) transporter
KK132_RS17955	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KK132_RS17960	COG1091	dTDP-4-dehydrorhamnose reductase activity
KK132_RS17965	COG1088	dTDP-glucose 4,6-dehydratase activity
KK132_RS17970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KK132_RS17975	COG3980	spore coat polysaccharide biosynthesis protein
KK132_RS17980	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KK132_RS17985	COG2089	acid synthase
KK132_RS17990	COG0456	acetyltransferase
KK132_RS17995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KK132_RS18000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KK132_RS18005	COG0463	Glycosyl transferase, family 2
KK132_RS18015	COG2363	Small membrane protein
KK132_RS18020	COG2233	PERMEase
KK132_RS18035	COG1216	Glycosyl transferase, family 2
KK132_RS18050	COG1695	Transcriptional regulator
KK132_RS18055	COG0351	phosphomethylpyrimidine kinase
KK132_RS18065	COG1621	beta-fructofuranosidase activity
KK132_RS18070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK132_RS18070	COG1263	PTS System
KK132_RS18075	COG3711	transcriptional antiterminator
KK132_RS18085	COG1404	Belongs to the peptidase S8 family
KK132_RS18090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KK132_RS18095	COG0778	Nitroreductase
KK132_RS18100	COG0772	Belongs to the SEDS family
KK132_RS18105	COG0454	-acetyltransferase
KK132_RS18125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KK132_RS18130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KK132_RS18135	COG2261	transglycosylase associated protein
KK132_RS18140	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KK132_RS18145	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KK132_RS18150	COG2246	polysaccharide biosynthetic process
KK132_RS18155	COG1309	transcriptional regulator
KK132_RS18175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KK132_RS18180	COG2837	iron assimilation
KK132_RS18200	COG0583	DNA-binding transcription factor activity
KK132_RS18210	COG1346	cytolysis
KK132_RS18215	COG4895	conserved protein (DUF2196)
KK132_RS18220	COG0789	Transcriptional regulator
KK132_RS18225	COG5504	Zn-dependent protease
KK132_RS18230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KK132_RS18235	COG0346	lactoylglutathione lyase activity
KK132_RS18240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK132_RS18245	COG1404	Belongs to the peptidase S8 family
KK132_RS18250	COG1442	glycosyl transferase family 8
KK132_RS18255	COG2357	RelA SpoT domain protein
KK132_RS18260	COG1575	Belongs to the MenA family. Type 1 subfamily
KK132_RS18275	COG1696	Membrane protein involved in D-alanine export
KK132_RS18285	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KK132_RS18290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KK132_RS18295	COG1486	melibiose metabolic process
KK132_RS18300	COG1447	Phosphotransferase system cellobiose-specific component IIA
KK132_RS18305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK132_RS18310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK132_RS18315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK132_RS18315	COG3711	transcriptional antiterminator
KK132_RS18330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK132_RS18335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK132_RS18345	COG0640	Transcriptional regulator
KK132_RS18350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KK132_RS18355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK132_RS18360	COG1447	Phosphotransferase system cellobiose-specific component IIA
KK132_RS18365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK132_RS18370	COG2723	6-phospho-beta-galactosidase activity
KK132_RS18380	COG1482	cell wall glycoprotein biosynthetic process
KK132_RS18390	COG0753	catalase activity
KK132_RS18395	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KK132_RS18400	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KK132_RS18420	COG3279	Response regulator of the LytR AlgR family
KK132_RS18440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KK132_RS18445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KK132_RS18450	COG4988	ABC transporter
KK132_RS18455	COG1294	oxidase, subunit
KK132_RS18460	COG1271	oxidase subunit
KK132_RS18465	COG3493	citrate carrier protein
KK132_RS18470	COG0726	polysaccharide deacetylase
KK132_RS18475	COG3842	ATPase activity
KK132_RS18480	COG2508	Transcriptional regulator
KK132_RS18485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KK132_RS18495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KK132_RS18510	COG4894	glucomannan catabolic process
KK132_RS18515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KK132_RS18520	COG0500	methyltransferase
KK132_RS18525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KK132_RS18540	COG0753	catalase activity
KK132_RS18540	COG0693	protein deglycase activity
KK132_RS18545	COG2851	Citrate transporter
KK132_RS18550	COG2273	Hydrolase Family 16
KK132_RS18560	COG2270	Major facilitator Superfamily
KK132_RS18565	COG0513	Belongs to the DEAD box helicase family
KK132_RS18575	COG0697	spore germination
KK132_RS18580	COG0589	response to stress
KK132_RS18640	COG3507	Belongs to the glycosyl hydrolase 43 family
KK132_RS18665	COG0010	Belongs to the arginase family
KK132_RS18670	COG0833	amino acid
KK132_RS18675	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KK132_RS18680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KK132_RS18690	COG2390	Transcriptional regulator
KK132_RS18695	COG0561	phosphatase activity
KK132_RS18725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KK132_RS18730	COG5294	Protein conserved in bacteria
KK132_RS18735	COG0577	efflux transmembrane transporter activity
KK132_RS18740	COG1136	(ABC) transporter
KK132_RS18745	COG2205	protein histidine kinase activity
KK132_RS18750	COG0745	RESPONSE REGULATOR receiver
KK132_RS18755	COG2205	protein histidine kinase activity
KK132_RS18760	COG0745	RESPONSE REGULATOR receiver
KK132_RS18790	COG1082	Xylose isomerase domain protein TIM barrel
KK132_RS18800	COG2814	Major facilitator Superfamily
KK132_RS18830	COG1349	DNA-binding transcription factor activity
KK132_RS18835	COG0667	Aldo Keto reductase
KK132_RS18840	COG2814	Major facilitator Superfamily
KK132_RS18855	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS18860	COG2197	response regulator
KK132_RS18865	COG4585	Histidine kinase
KK132_RS18870	COG3239	Fatty acid desaturase
KK132_RS18875	COG1309	transcriptional regulator
KK132_RS18880	COG1012	belongs to the aldehyde dehydrogenase family
KK132_RS18885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KK132_RS18895	COG0640	Transcriptional regulator
KK132_RS18900	COG2814	Major facilitator Superfamily
KK132_RS18905	COG1714	RDD family
KK132_RS18915	COG0450	alkyl hydroperoxide reductase
KK132_RS18920	COG3634	alkyl hydroperoxide reductase activity
KK132_RS18925	COG3177	Filamentation induced by cAMP protein fic
KK132_RS18930	COG1113	amino acid transport
KK132_RS18940	COG2080	2 iron, 2 sulfur cluster binding
KK132_RS18955	COG2068	MobA-Related Protein
KK132_RS18960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KK132_RS19015	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KK132_RS19020	COG0667	Aldo Keto reductase
KK132_RS19025	COG0456	acetyltransferase
KK132_RS19035	COG0457	Tetratricopeptide repeat
KK132_RS19040	COG0010	Belongs to the arginase family
KK132_RS19045	COG0833	amino acid
KK132_RS19050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KK132_RS19055	COG5658	integral membrane protein
KK132_RS19060	COG0640	Transcriptional regulator
KK132_RS19065	COG3829	transcription factor binding
KK132_RS19075	COG0488	(ABC) transporter
KK132_RS19090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KK132_RS19095	COG5002	protein histidine kinase activity
KK132_RS19095	COG3850	Histidine kinase
KK132_RS19105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KK132_RS19110	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KK132_RS19115	COG4853	Protein conserved in bacteria
KK132_RS19120	COG4863	YycH protein
KK132_RS19125	COG5002	protein histidine kinase activity
KK132_RS19130	COG0745	RESPONSE REGULATOR receiver
KK132_RS19160	COG0346	lactoylglutathione lyase activity
KK132_RS19165	COG0305	Participates in initiation and elongation during chromosome replication
KK132_RS19180	COG3093	addiction module antidote protein HigA
KK132_RS19185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KK132_RS19190	COG0297	glycogen (starch) synthase activity
KK132_RS19200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KK132_RS19205	COG0438	transferase activity, transferring glycosyl groups
KK132_RS19225	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KK132_RS19230	COG4241	membrane
KK132_RS19240	COG5577	PFAM Coat F domain
KK132_RS19245	COG1733	regulation of RNA biosynthetic process
KK132_RS19255	COG0697	spore germination
KK132_RS19260	COG1621	beta-fructofuranosidase activity
KK132_RS19265	COG1621	beta-fructofuranosidase activity
KK132_RS19275	COG2318	DinB family
KK132_RS19280	COG2211	Major facilitator Superfamily
KK132_RS19290	COG0778	Nitroreductase
KK132_RS19300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KK132_RS19305	COG1846	Transcriptional regulator
KK132_RS19310	COG2153	protein acetylation
KK132_RS19320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KK132_RS19325	COG0583	DNA-binding transcription factor activity
KK132_RS19330	COG1028	Short-chain dehydrogenase reductase Sdr
KK132_RS19335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KK132_RS19340	COG0697	spore germination
KK132_RS19370	COG1331	Highly conserved protein containing a thioredoxin domain
KK132_RS19375	COG1266	CAAX protease self-immunity
KK132_RS19380	COG0477	Major facilitator Superfamily
KK132_RS19380	COG2814	Major facilitator Superfamily
KK132_RS19385	COG0346	lactoylglutathione lyase activity
KK132_RS19390	COG1609	Transcriptional regulator
KK132_RS19395	COG0708	Exodeoxyribonuclease III
KK132_RS19400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KK132_RS19405	COG2169	Transcriptional regulator
KK132_RS19415	COG0629	single-stranded DNA binding
KK132_RS19425	COG0012	GTP binding
KK132_RS19430	COG0243	molybdopterin cofactor binding
KK132_RS19435	COG4481	Protein conserved in bacteria
KK132_RS19440	COG3949	Membrane
KK132_RS19455	COG1475	DNA binding
KK132_RS19460	COG1192	Involved in chromosome partitioning
KK132_RS19485	COG1847	R3H domain protein
KK132_RS19490	COG0706	membrane insertase activity