locus-tag	class	description
A1D33_RS00005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS00010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS00020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS00025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS00025	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A1D33_RS00035	COG1649	PFAM Uncharacterised BCR, COG1649
A1D33_RS00040	COG1960	acyl-CoA dehydrogenase activity
A1D33_RS00045	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS00050	COG0439	Biotin carboxylase
A1D33_RS00055	COG0511	ligase activity, forming carbon-carbon bonds
A1D33_RS00060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A1D33_RS00065	COG1024	Enoyl-CoA hydratase
A1D33_RS00070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A1D33_RS00075	COG0586	Pfam SNARE associated Golgi protein
A1D33_RS00080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A1D33_RS00085	COG2246	polysaccharide biosynthetic process
A1D33_RS00095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A1D33_RS00115	COG2124	cytochrome p450
A1D33_RS00120	COG2610	gluconate transmembrane transporter activity
A1D33_RS00125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A1D33_RS00130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A1D33_RS00135	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS00160	COG3507	Belongs to the glycosyl hydrolase 43 family
A1D33_RS00170	COG0745	RESPONSE REGULATOR receiver
A1D33_RS00175	COG2205	protein histidine kinase activity
A1D33_RS00205	COG1136	(ABC) transporter
A1D33_RS00205	COG0577	efflux transmembrane transporter activity
A1D33_RS00230	COG0457	Tetratricopeptide repeat
A1D33_RS00265	COG2271	Major facilitator Superfamily
A1D33_RS00270	COG1609	Transcriptional regulator
A1D33_RS00275	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS00280	COG1312	Catalyzes the dehydration of D-mannonate
A1D33_RS00285	COG0800	Aldolase
A1D33_RS00290	COG1063	alcohol dehydrogenase
A1D33_RS00300	COG1115	amino acid carrier protein
A1D33_RS00310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A1D33_RS00315	COG0187	DNA topoisomerase II activity
A1D33_RS00320	COG1832	CoA-binding protein
A1D33_RS00330	COG4841	protein insertion into membrane
A1D33_RS00340	COG0824	Thioesterase
A1D33_RS00360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS00365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A1D33_RS00380	COG0071	Belongs to the small heat shock protein (HSP20) family
A1D33_RS00390	COG4846	Membrane protein involved in cytochrome C biogenesis
A1D33_RS00395	COG2201	protein-glutamate methylesterase activity
A1D33_RS00400	COG0785	Cytochrome C biogenesis protein
A1D33_RS00420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A1D33_RS00430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A1D33_RS00460	COG4195	phage-related replication protein
A1D33_RS00465	COG0756	dUTP diphosphatase activity
A1D33_RS00470	COG5434	Belongs to the glycosyl hydrolase 28 family
A1D33_RS00480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1D33_RS00485	COG3397	chitin binding
A1D33_RS00505	COG0456	acetyltransferase
A1D33_RS00525	COG1064	alcohol dehydrogenase
A1D33_RS00530	COG2318	DinB family
A1D33_RS00545	COG3848	Pyruvate phosphate dikinase
A1D33_RS00545	COG0574	Belongs to the PEP-utilizing enzyme family
A1D33_RS00550	COG1070	Carbohydrate kinase
A1D33_RS00565	COG3507	Belongs to the glycosyl hydrolase 43 family
A1D33_RS00570	COG2211	Major facilitator Superfamily
A1D33_RS00590	COG5444	nuclease activity
A1D33_RS00595	COG4282	regulation of fungal-type cell wall biogenesis
A1D33_RS00610	COG0174	glutamine synthetase
A1D33_RS00615	COG0789	Transcriptional regulator
A1D33_RS00620	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A1D33_RS00625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A1D33_RS00630	COG0464	growth
A1D33_RS00640	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS00645	COG4112	unkown
A1D33_RS00650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A1D33_RS00655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A1D33_RS00695	COG2076	Multidrug Resistance protein
A1D33_RS00705	COG1764	response to oxidative stress
A1D33_RS00710	COG4195	phage-related replication protein
A1D33_RS00720	COG1404	Belongs to the peptidase S8 family
A1D33_RS00730	COG3619	membrane
A1D33_RS00735	COG3209	COG3209 Rhs family protein
A1D33_RS00740	COG2124	cytochrome p450
A1D33_RS00745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS00745	COG3321	synthase
A1D33_RS00745	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A1D33_RS00745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A1D33_RS00750	COG4221	oxidoreductase activity
A1D33_RS00750	COG3321	synthase
A1D33_RS00750	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS00750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS00755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D33_RS00755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS00755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS00755	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS00755	COG3321	synthase
A1D33_RS00755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS00755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D33_RS00755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS00755	COG3321	synthase
A1D33_RS00755	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS00760	COG0300	oxidoreductase activity
A1D33_RS00760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS00760	COG4221	oxidoreductase activity
A1D33_RS00760	COG3321	synthase
A1D33_RS00765	COG0300	oxidoreductase activity
A1D33_RS00765	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS00765	COG3321	synthase
A1D33_RS00765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS00765	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS00770	COG1024	Enoyl-CoA hydratase
A1D33_RS00775	COG1024	Enoyl-CoA hydratase
A1D33_RS00780	COG3425	synthase
A1D33_RS00785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS00825	COG0582	viral genome integration into host DNA
A1D33_RS00845	COG4550	Control of competence regulator ComK, YlbF/YmcA
A1D33_RS00865	COG2359	stage V sporulation protein S
A1D33_RS00870	COG1692	metallophosphoesterase
A1D33_RS00880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A1D33_RS00895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A1D33_RS00900	COG1426	Protein conserved in bacteria
A1D33_RS00915	COG0300	oxidoreductase activity
A1D33_RS00920	COG0612	Peptidase, M16
A1D33_RS00925	COG0612	Peptidase, M16
A1D33_RS00930	COG2409	Drug exporters of the RND superfamily
A1D33_RS00930	COG1033	growth of symbiont in host cell
A1D33_RS00935	COG1846	Transcriptional regulator
A1D33_RS00940	COG2814	Major facilitator Superfamily
A1D33_RS00945	COG2188	Transcriptional regulator
A1D33_RS00950	COG1674	ftsk spoiiie
A1D33_RS00950	COG4980	gas vesicle protein
A1D33_RS00960	COG0740	serine-type endopeptidase activity
A1D33_RS00965	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A1D33_RS00975	COG0527	aspartate kinase activity
A1D33_RS00980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A1D33_RS00985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A1D33_RS00990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A1D33_RS00995	COG1873	PFAM PRC-barrel domain
A1D33_RS01000	COG0612	Peptidase, M16
A1D33_RS01005	COG0726	polysaccharide deacetylase
A1D33_RS01020	COG0196	riboflavin kinase activity
A1D33_RS01035	COG1550	Protein conserved in bacteria
A1D33_RS01045	COG1358	cellular component organization or biogenesis
A1D33_RS01050	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A1D33_RS01055	COG0195	Participates in both transcription termination and antitermination
A1D33_RS01065	COG2176	DNA-directed DNA polymerase activity
A1D33_RS01075	COG0750	zinc metalloprotease
A1D33_RS01085	COG4589	Belongs to the CDS family
A1D33_RS01090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A1D33_RS01120	COG1191	sigma factor activity
A1D33_RS01130	COG1776	CheC inhibitor of MCP methylation
A1D33_RS01135	COG0835	chemotaxis
A1D33_RS01140	COG0643	Histidine kinase
A1D33_RS01140	COG2198	Histidine kinase
A1D33_RS01145	COG2201	protein-glutamate methylesterase activity
A1D33_RS01150	COG0455	bacterial-type flagellum organization
A1D33_RS01155	COG1419	protein localization to endoplasmic reticulum
A1D33_RS01160	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A1D33_RS01165	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A1D33_RS01170	COG1684	flagellar biosynthetic protein fliR
A1D33_RS01175	COG1987	bacterial-type flagellum assembly
A1D33_RS01180	COG1338	Plays a role in the flagellum-specific transport system
A1D33_RS01185	COG3190	flagellar
A1D33_RS01190	COG2201	protein-glutamate methylesterase activity
A1D33_RS01195	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A1D33_RS01195	COG1776	CheC inhibitor of MCP methylation
A1D33_RS01200	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A1D33_RS01205	COG1580	Controls the rotational direction of flagella during chemotaxis
A1D33_RS01210	COG1582	Flagellar protein (FlbD)
A1D33_RS01215	COG4786	Flagellar basal body rod
A1D33_RS01220	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A1D33_RS01225	COG3144	bacterial-type flagellum assembly
A1D33_RS01230	COG3334	PFAM MgtE intracellular
A1D33_RS01235	COG2882	bacterial-type flagellum organization
A1D33_RS01240	COG1157	protein secretion by the type III secretion system
A1D33_RS01245	COG1317	bacterial-type flagellum organization
A1D33_RS01250	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A1D33_RS01255	COG1766	The M ring may be actively involved in energy transduction
A1D33_RS01260	COG1677	Flagellar hook-basal body complex protein FliE
A1D33_RS01265	COG1558	bacterial-type flagellum-dependent cell motility
A1D33_RS01270	COG1815	bacterial-type flagellum-dependent cell motility
A1D33_RS01290	COG4974	Belongs to the 'phage' integrase family
A1D33_RS01300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A1D33_RS01305	COG0758	DNA mediated transformation
A1D33_RS01310	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A1D33_RS01320	COG2257	FlhB HrpN YscU SpaS Family
A1D33_RS01335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A1D33_RS01360	COG1837	Belongs to the UPF0109 family
A1D33_RS01370	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A1D33_RS01385	COG0552	protein localization to endoplasmic reticulum
A1D33_RS01390	COG1196	nuclear chromosome segregation
A1D33_RS01405	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS01410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A1D33_RS01425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A1D33_RS01430	COG1760	l-serine dehydratase
A1D33_RS01435	COG1760	l-serine dehydratase
A1D33_RS01440	COG1461	Dihydroxyacetone kinase
A1D33_RS01445	COG1302	Protein conserved in bacteria
A1D33_RS01460	COG1564	THIamine pyrophosphokinase
A1D33_RS01465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A1D33_RS01475	COG2815	serine threonine protein kinase
A1D33_RS01475	COG0515	serine threonine protein kinase
A1D33_RS01480	COG0631	protein serine/threonine phosphatase activity
A1D33_RS01490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A1D33_RS01490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A1D33_RS01500	COG0242	peptide deformylase activity
A1D33_RS01505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A1D33_RS01510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A1D33_RS01520	COG0194	GDP metabolic process
A1D33_RS01530	COG1561	YicC-like family, N-terminal region
A1D33_RS01535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A1D33_RS01545	COG1648	precorrin-2 dehydrogenase activity
A1D33_RS01550	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
A1D33_RS01555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A1D33_RS01570	COG0306	phosphate transporter
A1D33_RS01580	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A1D33_RS01585	COG0284	orotidine-5'-phosphate decarboxylase activity
A1D33_RS01600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A1D33_RS01605	COG0505	Belongs to the CarA family
A1D33_RS01610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A1D33_RS01620	COG2233	PERMEase
A1D33_RS01630	COG0564	pseudouridine synthase activity
A1D33_RS01640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A1D33_RS01645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A1D33_RS01655	COG3599	regulation of cell shape
A1D33_RS01660	COG2302	S4 RNA-binding domain
A1D33_RS01665	COG0762	integral membrane protein
A1D33_RS01675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A1D33_RS01680	COG1496	oxidoreductase activity
A1D33_RS01685	COG1873	PFAM PRC-barrel domain
A1D33_RS01690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A1D33_RS01695	COG1119	ATPase activity
A1D33_RS01700	COG1191	sigma factor activity
A1D33_RS01705	COG1191	sigma factor activity
A1D33_RS01715	COG4412	M6 family metalloprotease domain protein
A1D33_RS01715	COG1404	Belongs to the peptidase S8 family
A1D33_RS01720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A1D33_RS01725	COG0849	cell division
A1D33_RS01730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A1D33_RS01745	COG0772	Belongs to the SEDS family
A1D33_RS01765	COG0768	penicillin binding
A1D33_RS01770	COG0768	penicillin binding
A1D33_RS01775	COG4839	cell division protein FtsL
A1D33_RS01795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A1D33_RS01810	COG1399	metal-binding, possibly nucleic acid-binding protein
A1D33_RS01820	COG3480	Lon protease (S16) C-terminal proteolytic domain
A1D33_RS01825	COG1752	Esterase of the alpha-beta hydrolase superfamily
A1D33_RS01830	COG3314	Sporulation integral membrane protein YlbJ
A1D33_RS01840	COG0742	ribosomal rna small subunit methyltransferase
A1D33_RS01850	COG3679	Belongs to the UPF0342 family
A1D33_RS01865	COG2340	Cysteine-rich secretory protein family
A1D33_RS01870	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A1D33_RS01880	COG3336	cytochrome c oxidase
A1D33_RS01885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A1D33_RS01890	COG1845	cytochrome c oxidase, subunit III
A1D33_RS01895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A1D33_RS01900	COG2010	Cytochrome c
A1D33_RS01900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A1D33_RS01915	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A1D33_RS01920	COG0772	Belongs to the SEDS family
A1D33_RS01930	COG2066	Belongs to the glutaminase family
A1D33_RS01935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A1D33_RS01940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A1D33_RS01950	COG4896	Protein conserved in bacteria
A1D33_RS01960	COG1217	gtp-binding protein TYPA
A1D33_RS01980	COG1595	DNA-templated transcription, initiation
A1D33_RS01995	COG3227	Zinc metalloprotease (Elastase)
A1D33_RS02005	COG0483	inositol monophosphate 1-phosphatase activity
A1D33_RS02025	COG1982	Orn Lys Arg decarboxylase major
A1D33_RS02035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS02040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1D33_RS02045	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1D33_RS02050	COG0022	dehydrogenase e1 component
A1D33_RS02055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A1D33_RS02060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A1D33_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS02065	COG3321	synthase
A1D33_RS02065	COG4221	oxidoreductase activity
A1D33_RS02065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS02070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS02070	COG0300	oxidoreductase activity
A1D33_RS02070	COG3321	synthase
A1D33_RS02070	COG4221	oxidoreductase activity
A1D33_RS02075	COG3321	synthase
A1D33_RS02075	COG0300	oxidoreductase activity
A1D33_RS02075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS02075	COG4221	oxidoreductase activity
A1D33_RS02080	COG4221	oxidoreductase activity
A1D33_RS02080	COG3321	synthase
A1D33_RS02080	COG0300	oxidoreductase activity
A1D33_RS02080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS02085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS02085	COG3321	synthase
A1D33_RS02085	COG4221	oxidoreductase activity
A1D33_RS02090	COG4221	oxidoreductase activity
A1D33_RS02090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS02090	COG0300	oxidoreductase activity
A1D33_RS02090	COG3321	synthase
A1D33_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS02095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS02095	COG4221	oxidoreductase activity
A1D33_RS02095	COG3321	synthase
A1D33_RS02110	COG0497	DNA recombination
A1D33_RS02120	COG0242	peptide deformylase activity
A1D33_RS02125	COG0561	phosphatase activity
A1D33_RS02135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A1D33_RS02145	COG0569	domain protein
A1D33_RS02150	COG2105	PFAM AIG2 family protein
A1D33_RS02150	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A1D33_RS02155	COG3852	Histidine kinase
A1D33_RS02160	COG2002	toxin-antitoxin pair type II binding
A1D33_RS02170	COG1077	Cell shape determining protein MreB Mrl
A1D33_RS02175	COG2309	aminopeptidase activity
A1D33_RS02180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A1D33_RS02185	COG0488	(ABC) transporter
A1D33_RS02195	COG0681	Belongs to the peptidase S26 family
A1D33_RS02200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1D33_RS02200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1D33_RS02200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D33_RS02205	COG1105	Belongs to the carbohydrate kinase PfkB family
A1D33_RS02210	COG1349	DNA-binding transcription factor activity
A1D33_RS02215	COG0577	efflux transmembrane transporter activity
A1D33_RS02220	COG1136	(ABC) transporter
A1D33_RS02225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1D33_RS02235	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A1D33_RS02240	COG0314	molybdopterin synthase activity
A1D33_RS02245	COG1763	Mo-molybdopterin cofactor biosynthetic process
A1D33_RS02250	COG0303	'Molybdopterin
A1D33_RS02255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A1D33_RS02275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS02280	COG0668	transmembrane transport
A1D33_RS02300	COG0716	FMN binding
A1D33_RS02310	COG0716	FMN binding
A1D33_RS02315	COG0583	DNA-binding transcription factor activity
A1D33_RS02320	COG0517	IMP dehydrogenase activity
A1D33_RS02330	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A1D33_RS02335	COG4703	Protein of unknown function (DUF1797)
A1D33_RS02340	COG2200	EAL domain
A1D33_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS02355	COG1408	metallophosphoesterase
A1D33_RS02360	COG1376	ErfK ybiS ycfS ynhG family protein
A1D33_RS02365	COG2814	Major facilitator Superfamily
A1D33_RS02375	COG0835	chemotaxis
A1D33_RS02375	COG0784	Response regulator, receiver
A1D33_RS02380	COG0436	Aminotransferase
A1D33_RS02385	COG4191	Histidine kinase
A1D33_RS02390	COG0768	penicillin binding
A1D33_RS02395	COG2340	Cysteine-rich secretory protein family
A1D33_RS02400	COG2084	Dehydrogenase
A1D33_RS02405	COG0840	transmembrane signaling receptor activity
A1D33_RS02410	COG1533	DNA photolyase activity
A1D33_RS02420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A1D33_RS02425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D33_RS02430	COG2190	(PTS) system
A1D33_RS02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D33_RS02430	COG1263	PTS System
A1D33_RS02435	COG3711	transcriptional antiterminator
A1D33_RS02440	COG1609	Transcriptional regulator
A1D33_RS02445	COG0006	proline dipeptidase activity
A1D33_RS02450	COG2217	Heavy metal translocating P-type atpase
A1D33_RS02455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS02460	COG2244	polysaccharide biosynthetic process
A1D33_RS02465	COG3773	Cell wall hydrolase
A1D33_RS02475	COG4873	Protein conserved in bacteria
A1D33_RS02485	COG3858	chitin binding
A1D33_RS02490	COG1388	LysM domain
A1D33_RS02495	COG1388	LysM domain
A1D33_RS02495	COG4641	Protein conserved in bacteria
A1D33_RS02500	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS02505	COG1733	regulation of RNA biosynthetic process
A1D33_RS02515	COG0602	queuosine metabolic process
A1D33_RS02520	COG0720	synthase
A1D33_RS02535	COG3949	Membrane
A1D33_RS02540	COG0542	response to heat
A1D33_RS02545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A1D33_RS02550	COG1360	Flagellar Motor Protein
A1D33_RS02555	COG1846	Transcriptional regulator
A1D33_RS02560	COG3852	Histidine kinase
A1D33_RS02590	COG0436	Aminotransferase
A1D33_RS02595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1D33_RS02610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A1D33_RS02615	COG5002	protein histidine kinase activity
A1D33_RS02620	COG3594	Acyltransferase
A1D33_RS02625	COG2323	membrane
A1D33_RS02630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A1D33_RS02655	COG1191	sigma factor activity
A1D33_RS02660	COG0861	Integral membrane protein TerC family
A1D33_RS02665	COG0586	Pfam SNARE associated Golgi protein
A1D33_RS02670	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A1D33_RS02675	COG1793	dna ligase
A1D33_RS02675	COG3285	dna ligase
A1D33_RS02680	COG0726	polysaccharide deacetylase
A1D33_RS02685	COG1846	Transcriptional regulator
A1D33_RS02695	COG0789	Transcriptional regulator
A1D33_RS02700	COG2239	Acts as a magnesium transporter
A1D33_RS02705	COG3858	chitin binding
A1D33_RS02705	COG1388	LysM domain
A1D33_RS02710	COG4721	ABC-type cobalt transport system, permease component
A1D33_RS02715	COG1122	ATPase activity
A1D33_RS02720	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A1D33_RS02725	COG1366	Belongs to the anti-sigma-factor antagonist family
A1D33_RS02730	COG1404	Belongs to the peptidase S8 family
A1D33_RS02740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A1D33_RS02745	COG2814	Major facilitator Superfamily
A1D33_RS02755	COG0463	Glycosyl transferase, family 2
A1D33_RS02755	COG0457	Tetratricopeptide repeat
A1D33_RS02770	COG1764	response to oxidative stress
A1D33_RS02775	COG1846	Transcriptional regulator
A1D33_RS02780	COG1764	response to oxidative stress
A1D33_RS02790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A1D33_RS02795	COG0788	formyltetrahydrofolate deformylase activity
A1D33_RS02800	COG2076	Multidrug Resistance protein
A1D33_RS02805	COG2076	Multidrug Resistance protein
A1D33_RS02810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1D33_RS02815	COG1607	acyl-coa hydrolase
A1D33_RS02820	COG1834	amidinotransferase
A1D33_RS02825	COG2706	6-phosphogluconolactonase activity
A1D33_RS02830	COG4608	Belongs to the ABC transporter superfamily
A1D33_RS02835	COG0791	NLP P60 protein
A1D33_RS02840	COG4948	Mandelate Racemase Muconate Lactonizing
A1D33_RS02845	COG1619	proteins homologs of microcin C7 resistance protein MccF
A1D33_RS02850	COG4166	transmembrane transport
A1D33_RS02855	COG0444	Belongs to the ABC transporter superfamily
A1D33_RS02860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1D33_RS02865	COG0601	transmembrane transport
A1D33_RS02870	COG2362	D-Aminopeptidase
A1D33_RS02875	COG0477	Major facilitator Superfamily
A1D33_RS02880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1D33_RS02890	COG0463	Glycosyl transferase, family 2
A1D33_RS02895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A1D33_RS02900	COG0346	lactoylglutathione lyase activity
A1D33_RS02905	COG0531	amino acid
A1D33_RS02910	COG1392	Phosphate transport regulator
A1D33_RS02915	COG0306	phosphate transporter
A1D33_RS02930	COG5632	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS02930	COG3409	Peptidoglycan-binding domain 1 protein
A1D33_RS02970	COG3778	Protein conserved in bacteria
A1D33_RS02975	COG3299	homolog of phage Mu protein gp47
A1D33_RS02980	COG3628	GPW Gp25 family protein
A1D33_RS02990	COG4193	domain, Protein
A1D33_RS02995	COG3953	SLT domain
A1D33_RS02995	COG5412	phage tail tape measure protein
A1D33_RS02995	COG3953	SLT domain
A1D33_RS02995	COG5412	phage tail tape measure protein
A1D33_RS02995	COG5412	phage tail tape measure protein
A1D33_RS02995	COG3953	SLT domain
A1D33_RS03040	COG4653	Phage capsid family
A1D33_RS03045	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A1D33_RS03050	COG5518	Phage portal protein
A1D33_RS03055	COG1783	phage Terminase large subunit
A1D33_RS03060	COG5484	DNA packaging
A1D33_RS03060	COG3728	DNA packaging
A1D33_RS03065	COG1595	DNA-templated transcription, initiation
A1D33_RS03080	COG1484	DNA-dependent DNA replication
A1D33_RS03085	COG1522	sequence-specific DNA binding
A1D33_RS03095	COG1396	sequence-specific DNA binding
A1D33_RS03100	COG2856	Zn peptidase
A1D33_RS03105	COG3546	catalase activity
A1D33_RS03110	COG4195	phage-related replication protein
A1D33_RS03120	COG3409	Peptidoglycan-binding domain 1 protein
A1D33_RS03120	COG1388	LysM domain
A1D33_RS03120	COG5632	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS03125	COG0457	Tetratricopeptide repeat
A1D33_RS03130	COG2318	DinB family
A1D33_RS03135	COG0730	response to heat
A1D33_RS03140	COG2721	sulfolactate sulfo-lyase activity
A1D33_RS03145	COG0246	Mannitol dehydrogenase
A1D33_RS03150	COG1609	Transcriptional regulator
A1D33_RS03155	COG2211	Major facilitator Superfamily
A1D33_RS03165	COG1252	NADH dehydrogenase
A1D33_RS03175	COG4297	protein containing double-stranded beta helix domain
A1D33_RS03180	COG0697	spore germination
A1D33_RS03185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A1D33_RS03190	COG0390	transport system, permease component
A1D33_RS03195	COG1587	Uroporphyrinogen-III synthase
A1D33_RS03205	COG1819	glycosyl
A1D33_RS03210	COG2124	cytochrome p450
A1D33_RS03215	COG2427	Protein of unknown function (DUF1641)
A1D33_RS03220	COG3383	formate dehydrogenase (NAD+) activity
A1D33_RS03230	COG2205	protein histidine kinase activity
A1D33_RS03240	COG1285	pathogenesis
A1D33_RS03275	COG1447	Phosphotransferase system cellobiose-specific component IIA
A1D33_RS03280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1D33_RS03280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1D33_RS03285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A1D33_RS03290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A1D33_RS03295	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A1D33_RS03305	COG1846	Transcriptional regulator
A1D33_RS03310	COG0477	Major facilitator Superfamily
A1D33_RS03315	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A1D33_RS03320	COG2367	Beta-lactamase
A1D33_RS03330	COG0135	phosphoribosylanthranilate isomerase activity
A1D33_RS03335	COG0537	adenosine 5'-monophosphoramidase activity
A1D33_RS03360	COG5444	nuclease activity
A1D33_RS03415	COG5444	nuclease activity
A1D33_RS03445	COG0626	cystathionine gamma-synthase activity
A1D33_RS03450	COG0626	cystathionine gamma-synthase activity
A1D33_RS03455	COG2382	esterase
A1D33_RS03465	COG2153	protein acetylation
A1D33_RS03475	COG1131	(ABC) transporter
A1D33_RS03495	COG0210	DNA helicase
A1D33_RS03550	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A1D33_RS03555	COG0351	phosphomethylpyrimidine kinase
A1D33_RS03560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A1D33_RS03570	COG2104	thiamine diphosphate biosynthetic process
A1D33_RS03575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A1D33_RS03580	COG0352	thiamine-phosphate diphosphorylase activity
A1D33_RS03585	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A1D33_RS03590	COG0475	glutathione-regulated potassium exporter activity
A1D33_RS03590	COG0569	domain protein
A1D33_RS03600	COG0564	pseudouridine synthase activity
A1D33_RS03605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A1D33_RS03610	COG2357	RelA SpoT domain protein
A1D33_RS03620	COG4116	CYTH
A1D33_RS03625	COG0741	lytic transglycosylase activity
A1D33_RS03630	COG2346	COG2346, Truncated hemoglobins
A1D33_RS03635	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A1D33_RS03640	COG1164	Oligoendopeptidase f
A1D33_RS03645	COG4469	Competence protein
A1D33_RS03650	COG4862	establishment of competence for transformation
A1D33_RS03655	COG0861	Integral membrane protein TerC family
A1D33_RS03660	COG1393	Belongs to the ArsC family
A1D33_RS03665	COG0456	acetyltransferase
A1D33_RS03675	COG4608	Belongs to the ABC transporter superfamily
A1D33_RS03680	COG0444	Belongs to the ABC transporter superfamily
A1D33_RS03685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1D33_RS03690	COG0601	transmembrane transport
A1D33_RS03695	COG4166	transmembrane transport
A1D33_RS03700	COG0180	Tryptophanyl-tRNA synthetase
A1D33_RS03710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1D33_RS03715	COG0601	transmembrane transport
A1D33_RS03725	COG4608	Belongs to the ABC transporter superfamily
A1D33_RS03730	COG0444	Belongs to the ABC transporter superfamily
A1D33_RS03735	COG5504	Zn-dependent protease
A1D33_RS03740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1D33_RS03745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A1D33_RS03760	COG1744	ABC transporter substrate-binding protein PnrA-like
A1D33_RS03770	COG2267	carboxylic ester hydrolase activity
A1D33_RS03790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A1D33_RS03795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A1D33_RS03800	COG0505	Belongs to the CarA family
A1D33_RS03815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A1D33_RS03825	COG2271	Major facilitator Superfamily
A1D33_RS03830	COG0277	FAD linked oxidase domain protein
A1D33_RS03840	COG2151	metal-sulfur cluster biosynthetic enzyme
A1D33_RS03845	COG1073	alpha beta
A1D33_RS03850	COG0561	phosphatase activity
A1D33_RS03865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A1D33_RS03870	COG1307	EDD domain protein, DegV family
A1D33_RS03875	COG2124	cytochrome p450
A1D33_RS03880	COG0840	transmembrane signaling receptor activity
A1D33_RS03885	COG1744	ABC transporter substrate-binding protein PnrA-like
A1D33_RS03890	COG2996	Protein conserved in bacteria
A1D33_RS03900	COG0646	methionine synthase
A1D33_RS03900	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A1D33_RS03905	COG2153	protein acetylation
A1D33_RS03910	COG1357	PFAM Pentapeptide repeats (8 copies)
A1D33_RS03915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A1D33_RS03920	COG1279	arginine transmembrane transporter activity
A1D33_RS03925	COG2318	DinB family
A1D33_RS03930	COG1917	Cupin 2, conserved barrel domain protein
A1D33_RS03930	COG2207	Transcriptional regulator
A1D33_RS03935	COG0534	Mate efflux family protein
A1D33_RS03940	COG1562	ergosterol biosynthetic process
A1D33_RS03945	COG0367	asparagine synthase
A1D33_RS03960	COG0179	Fumarylacetoacetate (FAA) hydrolase
A1D33_RS04000	COG1403	HNH endonuclease
A1D33_RS04005	COG0419	ATPase involved in DNA repair
A1D33_RS04010	COG0420	3'-5' exonuclease activity
A1D33_RS04025	COG2323	membrane
A1D33_RS04030	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A1D33_RS04040	COG2814	Major facilitator Superfamily
A1D33_RS04045	COG3180	Ammonia monooxygenase
A1D33_RS04050	COG1846	Transcriptional regulator
A1D33_RS04060	COG0681	Belongs to the peptidase S26 family
A1D33_RS04065	COG0398	Pfam SNARE associated Golgi protein
A1D33_RS04105	COG5646	InterPro IPR014922
A1D33_RS04115	COG4903	ComK protein
A1D33_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS04130	COG0723	plastoquinol--plastocyanin reductase activity
A1D33_RS04130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A1D33_RS04135	COG0840	transmembrane signaling receptor activity
A1D33_RS04140	COG1268	BioY protein
A1D33_RS04145	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS04150	COG0183	Belongs to the thiolase family
A1D33_RS04155	COG0406	alpha-ribazole phosphatase activity
A1D33_RS04160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A1D33_RS04170	COG1404	Belongs to the peptidase S8 family
A1D33_RS04175	COG0501	Belongs to the peptidase M48B family
A1D33_RS04185	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS04190	COG0702	epimerase
A1D33_RS04195	COG0095	Lipoate-protein ligase
A1D33_RS04200	COG1234	tRNA 3'-trailer cleavage
A1D33_RS04205	COG1301	dicarboxylic acid transport
A1D33_RS04210	COG1363	Peptidase, m42
A1D33_RS04220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A1D33_RS04225	COG1511	domain protein
A1D33_RS04230	COG1309	transcriptional regulator
A1D33_RS04235	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A1D33_RS04240	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A1D33_RS04250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A1D33_RS04255	COG2329	Antibiotic biosynthesis monooxygenase
A1D33_RS04260	COG3069	C4-dicarboxylate transmembrane transporter activity
A1D33_RS04265	COG1473	amidohydrolase
A1D33_RS04275	COG4473	ABC transporter
A1D33_RS04280	COG1131	(ABC) transporter
A1D33_RS04285	COG0537	adenosine 5'-monophosphoramidase activity
A1D33_RS04290	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A1D33_RS04305	COG4980	gas vesicle protein
A1D33_RS04335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A1D33_RS04350	COG4717	serine-type aminopeptidase activity
A1D33_RS04355	COG0420	3'-5' exonuclease activity
A1D33_RS04360	COG1668	transmembrane transport
A1D33_RS04365	COG4152	abc transporter atp-binding protein
A1D33_RS04375	COG1024	Enoyl-CoA hydratase
A1D33_RS04385	COG0490	domain, Protein
A1D33_RS04390	COG0475	glutathione-regulated potassium exporter activity
A1D33_RS04400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A1D33_RS04405	COG0561	phosphatase activity
A1D33_RS04410	COG4335	DNA alkylation repair
A1D33_RS04425	COG0189	ligase activity
A1D33_RS04430	COG0189	ligase activity
A1D33_RS04445	COG0702	epimerase
A1D33_RS04450	COG1132	(ABC) transporter
A1D33_RS04455	COG1132	(ABC) transporter
A1D33_RS04460	COG0589	response to stress
A1D33_RS04470	COG3226	Transcriptional regulator
A1D33_RS04475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A1D33_RS04480	COG0726	polysaccharide deacetylase
A1D33_RS04485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A1D33_RS04490	COG0668	transmembrane transport
A1D33_RS04495	COG0584	glycerophosphoryl diester phosphodiesterase
A1D33_RS04500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A1D33_RS04505	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A1D33_RS04510	COG1253	flavin adenine dinucleotide binding
A1D33_RS04515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1D33_RS04520	COG0436	Aminotransferase
A1D33_RS04525	COG0789	Transcriptional regulator
A1D33_RS04530	COG1253	flavin adenine dinucleotide binding
A1D33_RS04535	COG0204	Acyl-transferase
A1D33_RS04540	COG1595	DNA-templated transcription, initiation
A1D33_RS04555	COG0733	neurotransmitter:sodium symporter activity
A1D33_RS04560	COG0531	amino acid
A1D33_RS04565	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS04570	COG0372	Belongs to the citrate synthase family
A1D33_RS04575	COG0583	DNA-binding transcription factor activity
A1D33_RS04580	COG0791	NLP P60 protein
A1D33_RS04580	COG1388	LysM domain
A1D33_RS04585	COG1785	Belongs to the alkaline phosphatase family
A1D33_RS04590	COG2719	SpoVR family
A1D33_RS04595	COG0668	transmembrane transport
A1D33_RS04600	COG1959	2 iron, 2 sulfur cluster binding
A1D33_RS04605	COG0791	NLP P60 protein
A1D33_RS04605	COG1388	LysM domain
A1D33_RS04620	COG0431	NADPH-dependent FMN reductase
A1D33_RS04625	COG2197	response regulator
A1D33_RS04630	COG2203	Gaf domain
A1D33_RS04630	COG4585	Histidine kinase
A1D33_RS04635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A1D33_RS04640	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A1D33_RS04650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A1D33_RS04655	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A1D33_RS04660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A1D33_RS04665	COG3153	acetyltransferase
A1D33_RS04665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1D33_RS04670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1D33_RS04675	COG0517	IMP dehydrogenase activity
A1D33_RS04685	COG0564	pseudouridine synthase activity
A1D33_RS04690	COG3764	Sortase (surface protein transpeptidase)
A1D33_RS04695	COG4085	toxin activity
A1D33_RS04695	COG0737	Belongs to the 5'-nucleotidase family
A1D33_RS04695	COG1525	nuclease
A1D33_RS04700	COG5577	PFAM Coat F domain
A1D33_RS04720	COG1823	symporter activity
A1D33_RS04725	COG3706	GGDEF domain
A1D33_RS04730	COG1464	Belongs to the NlpA lipoprotein family
A1D33_RS04735	COG1278	Cold shock
A1D33_RS04740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A1D33_RS04745	COG1131	(ABC) transporter
A1D33_RS04750	COG1131	(ABC) transporter
A1D33_RS04755	COG1725	Transcriptional regulator
A1D33_RS04770	COG0655	NAD(P)H dehydrogenase (quinone) activity
A1D33_RS04775	COG2814	Major facilitator Superfamily
A1D33_RS04780	COG1566	PFAM secretion protein HlyD family protein
A1D33_RS04785	COG1846	Transcriptional regulator
A1D33_RS04795	COG2766	serine protein kinase
A1D33_RS04800	COG1664	Polymer-forming cytoskeletal
A1D33_RS04805	COG1664	Polymer-forming cytoskeletal
A1D33_RS04810	COG0789	Transcriptional regulator
A1D33_RS04815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A1D33_RS04825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A1D33_RS04830	COG3382	B3 4 domain protein
A1D33_RS04840	COG1476	TRANSCRIPTIONal
A1D33_RS04860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A1D33_RS04865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A1D33_RS04870	COG1116	anion transmembrane transporter activity
A1D33_RS04885	COG0753	catalase activity
A1D33_RS04890	COG4608	Belongs to the ABC transporter superfamily
A1D33_RS04895	COG0444	Belongs to the ABC transporter superfamily
A1D33_RS04900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1D33_RS04905	COG0601	transmembrane transport
A1D33_RS04910	COG0747	negative chemotaxis
A1D33_RS04920	COG0277	FAD linked oxidase domain protein
A1D33_RS04930	COG3340	Belongs to the peptidase S51 family
A1D33_RS04935	COG1757	Na H antiporter
A1D33_RS05045	COG0735	belongs to the Fur family
A1D33_RS05050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A1D33_RS05060	COG4129	membrane
A1D33_RS05065	COG1132	(ABC) transporter
A1D33_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS05095	COG1194	a g-specific adenine glycosylase
A1D33_RS05100	COG1988	membrane-bound metal-dependent
A1D33_RS05105	COG4485	Bacterial membrane protein, YfhO
A1D33_RS05110	COG0463	Glycosyl transferase, family 2
A1D33_RS05115	COG0596	Alpha beta hydrolase
A1D33_RS05120	COG5658	integral membrane protein
A1D33_RS05125	COG3103	Sh3 type 3 domain protein
A1D33_RS05140	COG3591	Belongs to the peptidase S1B family
A1D33_RS05150	COG2814	Major facilitator Superfamily
A1D33_RS05165	COG1090	epimerase
A1D33_RS05175	COG0778	Nitroreductase
A1D33_RS05180	COG0384	phenazine biosynthesis protein PhzF
A1D33_RS05185	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A1D33_RS05185	COG0392	lysyltransferase activity
A1D33_RS05190	COG1846	Transcriptional regulator
A1D33_RS05195	COG2814	Major facilitator Superfamily
A1D33_RS05200	COG2318	DinB family
A1D33_RS05205	COG2732	(Barnase) inhibitor
A1D33_RS05210	COG3848	Pyruvate phosphate dikinase
A1D33_RS05210	COG0574	Belongs to the PEP-utilizing enzyme family
A1D33_RS05220	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
A1D33_RS05225	COG2249	NAD(P)H dehydrogenase (quinone) activity
A1D33_RS05230	COG1695	Transcriptional regulator
A1D33_RS05245	COG2514	catechol 2,3-dioxygenase activity
A1D33_RS05250	COG2259	Doxx family
A1D33_RS05255	COG1132	(ABC) transporter
A1D33_RS05260	COG1132	(ABC) transporter
A1D33_RS05265	COG1263	PTS System
A1D33_RS05265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D33_RS05270	COG1737	Transcriptional regulator
A1D33_RS05275	COG1486	melibiose metabolic process
A1D33_RS05285	COG3284	Transcriptional regulator
A1D33_RS05290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1D33_RS05295	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1D33_RS05300	COG0022	dehydrogenase e1 component
A1D33_RS05305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A1D33_RS05310	COG4637	Psort location Cytoplasmic, score
A1D33_RS05315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A1D33_RS05325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A1D33_RS05330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A1D33_RS05335	COG0598	Magnesium transport protein CorA
A1D33_RS05345	COG2084	Dehydrogenase
A1D33_RS05350	COG0726	polysaccharide deacetylase
A1D33_RS05360	COG0535	radical SAM domain protein
A1D33_RS05365	COG0668	transmembrane transport
A1D33_RS05375	COG0387	Pfam Sodium calcium exchanger
A1D33_RS05380	COG0477	Major facilitator Superfamily
A1D33_RS05385	COG1295	ribonuclease BN
A1D33_RS05390	COG4980	gas vesicle protein
A1D33_RS05395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A1D33_RS05405	COG2814	Major facilitator Superfamily
A1D33_RS05420	COG1609	Transcriptional regulator
A1D33_RS05425	COG0693	protein deglycase activity
A1D33_RS05430	COG0737	Belongs to the 5'-nucleotidase family
A1D33_RS05445	COG0778	Nitroreductase
A1D33_RS05450	COG2188	Transcriptional regulator
A1D33_RS05455	COG0366	Alpha amylase catalytic
A1D33_RS05460	COG1263	PTS System
A1D33_RS05460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D33_RS05475	COG0071	Belongs to the small heat shock protein (HSP20) family
A1D33_RS05485	COG1368	sulfuric ester hydrolase activity
A1D33_RS05495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D33_RS05495	COG1263	PTS System
A1D33_RS05500	COG0024	Methionine aminopeptidase
A1D33_RS05510	COG2258	MOSC domain
A1D33_RS05520	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A1D33_RS05525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1D33_RS05530	COG2851	Citrate transporter
A1D33_RS05535	COG3181	Tripartite tricarboxylate transporter family receptor
A1D33_RS05540	COG4565	transcriptional regulatory protein
A1D33_RS05545	COG3290	protein histidine kinase activity
A1D33_RS05550	COG3764	Sortase (surface protein transpeptidase)
A1D33_RS05560	COG3279	Response regulator of the LytR AlgR family
A1D33_RS05565	COG2972	Histidine kinase
A1D33_RS05565	COG0745	RESPONSE REGULATOR receiver
A1D33_RS05585	COG0471	metal ion transport
A1D33_RS05590	COG3866	Pectate lyase
A1D33_RS05605	COG2130	NADP-dependent
A1D33_RS05610	COG0456	acetyltransferase
A1D33_RS05615	COG0513	Belongs to the DEAD box helicase family
A1D33_RS05620	COG0488	(ABC) transporter
A1D33_RS05625	COG2814	Major facilitator Superfamily
A1D33_RS05630	COG0789	Transcriptional regulator
A1D33_RS05635	COG0488	(ABC) transporter
A1D33_RS05640	COG0457	Tetratricopeptide repeat
A1D33_RS05640	COG0463	Glycosyl transferase, family 2
A1D33_RS05645	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS05650	COG0840	transmembrane signaling receptor activity
A1D33_RS05655	COG1012	belongs to the aldehyde dehydrogenase family
A1D33_RS05660	COG0531	amino acid
A1D33_RS05665	COG2223	nitrite transmembrane transporter activity
A1D33_RS05670	COG1442	glycosyl transferase family 8
A1D33_RS05675	COG1216	Glycosyl transferase, family 2
A1D33_RS05680	COG1442	glycosyl transferase family 8
A1D33_RS05685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D33_RS05690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A1D33_RS05695	COG1368	sulfuric ester hydrolase activity
A1D33_RS05705	COG1131	(ABC) transporter
A1D33_RS05720	COG2124	cytochrome p450
A1D33_RS05720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A1D33_RS05730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1D33_RS05735	COG1846	Transcriptional regulator
A1D33_RS05745	COG0670	Belongs to the BI1 family
A1D33_RS05750	COG0196	riboflavin kinase activity
A1D33_RS05755	COG1366	Belongs to the anti-sigma-factor antagonist family
A1D33_RS05760	COG0346	lactoylglutathione lyase activity
A1D33_RS05765	COG2329	Antibiotic biosynthesis monooxygenase
A1D33_RS05770	COG2323	membrane
A1D33_RS05780	COG0454	-acetyltransferase
A1D33_RS05785	COG3546	catalase activity
A1D33_RS05815	COG5444	nuclease activity
A1D33_RS05855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A1D33_RS05860	COG1597	lipid kinase activity
A1D33_RS05865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1D33_RS05870	COG1309	transcriptional regulator
A1D33_RS05890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A1D33_RS05895	COG1285	pathogenesis
A1D33_RS05900	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A1D33_RS05905	COG4851	CamS sex pheromone cAM373 precursor
A1D33_RS05915	COG0210	DNA helicase
A1D33_RS05930	COG0069	glutamate synthase activity
A1D33_RS05935	COG4496	protein, YerC YecD
A1D33_RS05940	COG1470	cell adhesion involved in biofilm formation
A1D33_RS05945	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A1D33_RS05955	COG0151	Belongs to the GarS family
A1D33_RS05960	COG0138	bifunctional purine biosynthesis protein purh
A1D33_RS05965	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A1D33_RS05975	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A1D33_RS05990	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A1D33_RS05995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A1D33_RS06000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A1D33_RS06005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A1D33_RS06010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A1D33_RS06030	COG3064	Membrane
A1D33_RS06035	COG2252	PERMEase
A1D33_RS06060	COG1305	Transglutaminase-like
A1D33_RS06065	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A1D33_RS06070	COG0714	Associated with various cellular activities
A1D33_RS06075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A1D33_RS06080	COG1113	amino acid transport
A1D33_RS06085	COG2132	Multicopper oxidase
A1D33_RS06095	COG0823	Involved in the tonB-independent uptake of proteins
A1D33_RS06100	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A1D33_RS06105	COG1063	alcohol dehydrogenase
A1D33_RS06110	COG1595	DNA-templated transcription, initiation
A1D33_RS06120	COG2755	lipolytic protein G-D-S-L family
A1D33_RS06120	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A1D33_RS06125	COG4260	virion core protein, lumpy skin disease virus
A1D33_RS06130	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A1D33_RS06135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A1D33_RS06140	COG1842	Phage shock protein A
A1D33_RS06150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D33_RS06155	COG2211	Major facilitator Superfamily
A1D33_RS06160	COG1063	alcohol dehydrogenase
A1D33_RS06165	COG0457	Tetratricopeptide repeat
A1D33_RS06190	COG1266	CAAX protease self-immunity
A1D33_RS06200	COG0805	protein transport
A1D33_RS06205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A1D33_RS06220	COG0488	(ABC) transporter
A1D33_RS06225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A1D33_RS06230	COG0456	acetyltransferase
A1D33_RS06235	COG1214	PFAM Peptidase M22, glycoprotease
A1D33_RS06240	COG0802	atpase or kinase
A1D33_RS06245	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A1D33_RS06285	COG2814	Major facilitator Superfamily
A1D33_RS06290	COG0604	alcohol dehydrogenase
A1D33_RS06295	COG3832	glyoxalase III activity
A1D33_RS06305	COG0531	amino acid
A1D33_RS06310	COG1309	transcriptional regulator
A1D33_RS06315	COG2076	Multidrug Resistance protein
A1D33_RS06320	COG2076	Multidrug Resistance protein
A1D33_RS06325	COG2807	transmembrane transport
A1D33_RS06330	COG2186	Transcriptional regulator
A1D33_RS06335	COG2188	Transcriptional regulator
A1D33_RS06340	COG2814	Major facilitator Superfamily
A1D33_RS06345	COG1388	LysM domain
A1D33_RS06350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A1D33_RS06365	COG1819	glycosyl
A1D33_RS06370	COG1802	Transcriptional regulator
A1D33_RS06385	COG0473	3-isopropylmalate dehydrogenase activity
A1D33_RS06390	COG2226	methyltransferase
A1D33_RS06395	COG1051	belongs to the nudix hydrolase family
A1D33_RS06400	COG4978	Transcriptional regulator
A1D33_RS06400	COG0789	Transcriptional regulator
A1D33_RS06405	COG0456	acetyltransferase
A1D33_RS06410	COG0730	response to heat
A1D33_RS06420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1D33_RS06425	COG2814	Major facilitator Superfamily
A1D33_RS06435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A1D33_RS06440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1D33_RS06445	COG0488	(ABC) transporter
A1D33_RS06450	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A1D33_RS06455	COG2409	Drug exporters of the RND superfamily
A1D33_RS06460	COG2197	response regulator
A1D33_RS06465	COG4585	Histidine kinase
A1D33_RS06480	COG5577	PFAM Coat F domain
A1D33_RS06485	COG1063	alcohol dehydrogenase
A1D33_RS06495	COG5577	PFAM Coat F domain
A1D33_RS06500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A1D33_RS06505	COG0697	spore germination
A1D33_RS06510	COG1309	transcriptional regulator
A1D33_RS06515	COG2814	Major facilitator Superfamily
A1D33_RS06530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A1D33_RS06540	COG0789	Transcriptional regulator
A1D33_RS06545	COG1064	alcohol dehydrogenase
A1D33_RS06560	COG0351	phosphomethylpyrimidine kinase
A1D33_RS06595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A1D33_RS06615	COG0277	FAD linked oxidase domain protein
A1D33_RS06630	COG0662	Cupin 2, conserved barrel domain protein
A1D33_RS06640	COG3621	Patatin-like phospholipase
A1D33_RS06655	COG1794	racemase activity, acting on amino acids and derivatives
A1D33_RS06660	COG1329	Transcriptional regulator
A1D33_RS06665	COG1278	Cold shock
A1D33_RS06670	COG3239	Fatty acid desaturase
A1D33_RS06675	COG2910	NAD(P)H-binding
A1D33_RS06680	COG1959	2 iron, 2 sulfur cluster binding
A1D33_RS06690	COG2030	dehydratase
A1D33_RS06700	COG0477	Major facilitator Superfamily
A1D33_RS06710	COG2249	NAD(P)H dehydrogenase (quinone) activity
A1D33_RS06755	COG2183	response to ionizing radiation
A1D33_RS06760	COG2208	phosphoserine phosphatase activity
A1D33_RS06765	COG1191	sigma factor activity
A1D33_RS06775	COG1366	Belongs to the anti-sigma-factor antagonist family
A1D33_RS06780	COG2208	phosphoserine phosphatase activity
A1D33_RS06785	COG2172	sigma factor antagonist activity
A1D33_RS06790	COG1366	Belongs to the anti-sigma-factor antagonist family
A1D33_RS06795	COG1366	Belongs to the anti-sigma-factor antagonist family
A1D33_RS06800	COG2337	Toxic component of a toxin-antitoxin (TA) module
A1D33_RS06805	COG0864	Transcriptional regulator
A1D33_RS06810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A1D33_RS06815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A1D33_RS06825	COG0705	Rhomboid family
A1D33_RS06830	COG3428	Bacterial PH domain
A1D33_RS06835	COG3402	PFAM membrane-flanked domain
A1D33_RS06840	COG0513	Belongs to the DEAD box helicase family
A1D33_RS06845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A1D33_RS06855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS06860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A1D33_RS06870	COG1960	acyl-CoA dehydrogenase activity
A1D33_RS06880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A1D33_RS06885	COG1131	(ABC) transporter
A1D33_RS06890	COG0628	permease
A1D33_RS06895	COG1301	dicarboxylic acid transport
A1D33_RS06900	COG4565	transcriptional regulatory protein
A1D33_RS06905	COG3290	protein histidine kinase activity
A1D33_RS06910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A1D33_RS06915	COG3546	catalase activity
A1D33_RS06920	COG2329	Antibiotic biosynthesis monooxygenase
A1D33_RS06925	COG0662	Cupin 2, conserved barrel domain protein
A1D33_RS06930	COG3729	General stress protein
A1D33_RS06935	COG2217	Heavy metal translocating P-type atpase
A1D33_RS06940	COG2076	Multidrug Resistance protein
A1D33_RS06950	COG4876	unkown
A1D33_RS06960	COG1914	H( )-stimulated, divalent metal cation uptake system
A1D33_RS06990	COG0457	Tetratricopeptide repeat
A1D33_RS07015	COG0028	Belongs to the TPP enzyme family
A1D33_RS07020	COG0494	nUDIX hydrolase
A1D33_RS07025	COG0531	amino acid
A1D33_RS07035	COG1215	transferase activity, transferring glycosyl groups
A1D33_RS07040	COG5298	Protein conserved in bacteria
A1D33_RS07045	COG3706	GGDEF domain
A1D33_RS07050	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A1D33_RS07055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A1D33_RS07055	COG0551	DNA topoisomerase type I activity
A1D33_RS07060	COG1522	sequence-specific DNA binding
A1D33_RS07065	COG2814	Major facilitator Superfamily
A1D33_RS07075	COG3871	stress protein (general stress protein 26)
A1D33_RS07080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1D33_RS07085	COG1917	Cupin 2, conserved barrel domain protein
A1D33_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS07095	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS07100	COG3711	transcriptional antiterminator
A1D33_RS07105	COG4989	oxidoreductase activity
A1D33_RS07110	COG0768	penicillin binding
A1D33_RS07115	COG2329	Antibiotic biosynthesis monooxygenase
A1D33_RS07125	COG2755	lipolytic protein G-D-S-L family
A1D33_RS07130	COG1414	Transcriptional regulator
A1D33_RS07135	COG1984	allophanate hydrolase subunit 2
A1D33_RS07140	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A1D33_RS07150	COG1914	H( )-stimulated, divalent metal cation uptake system
A1D33_RS07160	COG0561	phosphatase activity
A1D33_RS07165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A1D33_RS07175	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D33_RS07180	COG2213	PTS system mannitol-specific
A1D33_RS07190	COG1349	DNA-binding transcription factor activity
A1D33_RS07195	COG1276	copper resistance
A1D33_RS07195	COG2372	response to copper ion
A1D33_RS07200	COG4549	nuclear export factor GLE1
A1D33_RS07205	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS07210	COG4975	Glucose uptake
A1D33_RS07215	COG1012	belongs to the aldehyde dehydrogenase family
A1D33_RS07220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A1D33_RS07225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A1D33_RS07230	COG0640	Transcriptional regulator
A1D33_RS07235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A1D33_RS07240	COG0778	Nitroreductase
A1D33_RS07245	COG1309	transcriptional regulator
A1D33_RS07250	COG2814	Major facilitator Superfamily
A1D33_RS07255	COG4607	ABC-type enterochelin transport system periplasmic component
A1D33_RS07260	COG4604	ABC transporter, ATP-binding protein
A1D33_RS07265	COG4605	iron ion homeostasis
A1D33_RS07270	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D33_RS07275	COG0527	aspartate kinase activity
A1D33_RS07285	COG0457	Tetratricopeptide repeat
A1D33_RS07290	COG3850	Histidine kinase
A1D33_RS07290	COG5002	protein histidine kinase activity
A1D33_RS07295	COG0745	RESPONSE REGULATOR receiver
A1D33_RS07300	COG0577	efflux transmembrane transporter activity
A1D33_RS07305	COG1136	(ABC) transporter
A1D33_RS07310	COG2079	MmgE PrpD family protein
A1D33_RS07315	COG1473	amidohydrolase
A1D33_RS07320	COG1126	abc transporter atp-binding protein
A1D33_RS07325	COG0765	amino acid transport
A1D33_RS07330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D33_RS07335	COG0456	acetyltransferase
A1D33_RS07340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A1D33_RS07345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A1D33_RS07355	COG0697	spore germination
A1D33_RS07365	COG5434	Belongs to the glycosyl hydrolase 28 family
A1D33_RS07370	COG3104	oligopeptide transport
A1D33_RS07385	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A1D33_RS07390	COG0163	prenyltransferase activity
A1D33_RS07395	COG0583	DNA-binding transcription factor activity
A1D33_RS07400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D33_RS07405	COG0765	amino acid transport
A1D33_RS07410	COG1126	abc transporter atp-binding protein
A1D33_RS07415	COG2364	Membrane
A1D33_RS07425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A1D33_RS07430	COG0697	spore germination
A1D33_RS07445	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A1D33_RS07450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS07455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS07460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS07465	COG1733	regulation of RNA biosynthetic process
A1D33_RS07470	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A1D33_RS07475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A1D33_RS07480	COG3209	COG3209 Rhs family protein
A1D33_RS07490	COG2723	6-phospho-beta-galactosidase activity
A1D33_RS07500	COG1714	RDD family
A1D33_RS07505	COG1063	alcohol dehydrogenase
A1D33_RS07510	COG0523	cobalamin synthesis protein
A1D33_RS07515	COG2223	nitrite transmembrane transporter activity
A1D33_RS07520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A1D33_RS07525	COG0243	molybdopterin cofactor binding
A1D33_RS07530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A1D33_RS07535	COG2146	nitrite reductase [NAD(P)H] activity
A1D33_RS07540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A1D33_RS07540	COG1587	Uroporphyrinogen-III synthase
A1D33_RS07550	COG2508	Transcriptional regulator
A1D33_RS07555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A1D33_RS07560	COG1012	belongs to the aldehyde dehydrogenase family
A1D33_RS07565	COG0506	proline dehydrogenase activity
A1D33_RS07570	COG3541	Predicted nucleotidyltransferase
A1D33_RS07575	COG3458	cephalosporin-C deacetylase activity
A1D33_RS07580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A1D33_RS07585	COG2271	Major facilitator Superfamily
A1D33_RS07590	COG1082	Xylose isomerase domain protein TIM barrel
A1D33_RS07605	COG3665	Urea carboxylase-associated protein
A1D33_RS07610	COG1113	amino acid transport
A1D33_RS07615	COG3403	YqcI/YcgG family
A1D33_RS07620	COG1280	lysine exporter protein (LysE YggA)
A1D33_RS07625	COG1846	Transcriptional regulator
A1D33_RS07630	COG2814	Major facilitator Superfamily
A1D33_RS07640	COG0366	Alpha amylase catalytic
A1D33_RS07650	COG1288	antiporter activity
A1D33_RS07655	COG1473	amidohydrolase
A1D33_RS07660	COG2113	Glycine betaine
A1D33_RS07665	COG4176	ABC-type proline glycine betaine transport system permease component
A1D33_RS07670	COG0517	IMP dehydrogenase activity
A1D33_RS07670	COG4175	Glycine betaine
A1D33_RS07675	COG0477	Major facilitator Superfamily
A1D33_RS07680	COG3853	Toxic anion resistance protein (TelA)
A1D33_RS07690	COG0861	Integral membrane protein TerC family
A1D33_RS07695	COG2310	stress, protein
A1D33_RS07700	COG2310	stress, protein
A1D33_RS07705	COG2310	stress, protein
A1D33_RS07710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A1D33_RS07715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1D33_RS07720	COG1121	(ABC) transporter
A1D33_RS07725	COG0803	Belongs to the bacterial solute-binding protein 9 family
A1D33_RS07730	COG0366	Alpha amylase catalytic
A1D33_RS07735	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS07740	COG0457	Tetratricopeptide repeat
A1D33_RS07745	COG1876	peptidase activity
A1D33_RS07750	COG1595	DNA-templated transcription, initiation
A1D33_RS07755	COG1595	DNA-templated transcription, initiation
A1D33_RS07765	COG0667	Aldo Keto reductase
A1D33_RS07770	COG1405	negative regulation of cell septum assembly
A1D33_RS07770	COG3012	SEC-C Motif Domain Protein
A1D33_RS07775	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A1D33_RS07780	COG0252	asparaginase activity
A1D33_RS07785	COG1309	transcriptional regulator
A1D33_RS07790	COG0477	Major facilitator Superfamily
A1D33_RS07795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A1D33_RS07805	COG0805	protein transport
A1D33_RS07810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A1D33_RS07815	COG3540	Alkaline phosphatase
A1D33_RS07820	COG3773	Cell wall hydrolase
A1D33_RS07830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS07835	COG2259	Doxx family
A1D33_RS07840	COG0346	lactoylglutathione lyase activity
A1D33_RS07845	COG0778	Nitroreductase
A1D33_RS07850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A1D33_RS07865	COG3173	Aminoglycoside phosphotransferase
A1D33_RS07870	COG0784	Response regulator, receiver
A1D33_RS07875	COG4191	Histidine kinase
A1D33_RS07880	COG2066	Belongs to the glutaminase family
A1D33_RS07885	COG1115	amino acid carrier protein
A1D33_RS07890	COG2040	homocysteine
A1D33_RS07895	COG0833	amino acid
A1D33_RS07900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A1D33_RS07905	COG1301	dicarboxylic acid transport
A1D33_RS07920	COG0688	phosphatidylethanolamine metabolic process
A1D33_RS07925	COG0586	Pfam SNARE associated Golgi protein
A1D33_RS07930	COG1183	phosphatidylcholine synthase activity
A1D33_RS07940	COG0371	Dehydrogenase
A1D33_RS07955	COG3409	Peptidoglycan-binding domain 1 protein
A1D33_RS07965	COG2368	4-hydroxyphenylacetate
A1D33_RS07975	COG2271	Major facilitator Superfamily
A1D33_RS07980	COG0584	glycerophosphoryl diester phosphodiesterase
A1D33_RS07995	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
A1D33_RS08000	COG0531	amino acid
A1D33_RS08040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS08040	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS08040	COG0300	oxidoreductase activity
A1D33_RS08040	COG3321	synthase
A1D33_RS08040	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS08045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS08045	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS08045	COG4221	oxidoreductase activity
A1D33_RS08045	COG3321	synthase
A1D33_RS08065	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A1D33_RS08085	COG1131	(ABC) transporter
A1D33_RS08090	COG2197	response regulator
A1D33_RS08095	COG4585	Histidine kinase
A1D33_RS08100	COG1011	Hydrolase
A1D33_RS08105	COG1113	amino acid transport
A1D33_RS08110	COG1846	Transcriptional regulator
A1D33_RS08115	COG1380	Effector of murein hydrolase LrgA
A1D33_RS08120	COG1346	cytolysis
A1D33_RS08160	COG4856	YbbR-like protein
A1D33_RS08165	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A1D33_RS08170	COG5662	AntiSigma factor
A1D33_RS08175	COG1595	DNA-templated transcription, initiation
A1D33_RS08205	COG1683	Conserved Protein
A1D33_RS08210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1D33_RS08220	COG1263	PTS System
A1D33_RS08220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D33_RS08225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A1D33_RS08230	COG1472	Belongs to the glycosyl hydrolase 3 family
A1D33_RS08235	COG3876	Protein conserved in bacteria
A1D33_RS08240	COG2207	Transcriptional regulator
A1D33_RS08240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1D33_RS08245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1D33_RS08250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D33_RS08255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D33_RS08260	COG2819	hydrolase of the alpha beta superfamily
A1D33_RS08265	COG0385	Bile acid
A1D33_RS08270	COG0659	secondary active sulfate transmembrane transporter activity
A1D33_RS08285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A1D33_RS08350	COG0726	polysaccharide deacetylase
A1D33_RS08355	COG2194	sulfuric ester hydrolase activity
A1D33_RS08365	COG0489	protein tyrosine kinase activity
A1D33_RS08370	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS08380	COG2318	DinB family
A1D33_RS08385	COG2226	methyltransferase
A1D33_RS08405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A1D33_RS08410	COG1122	ATPase activity
A1D33_RS08415	COG1122	ATPase activity
A1D33_RS08440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A1D33_RS08450	COG0024	Methionine aminopeptidase
A1D33_RS08460	COG0201	protein transport
A1D33_RS08565	COG0596	Alpha beta hydrolase
A1D33_RS08590	COG1358	cellular component organization or biogenesis
A1D33_RS08605	COG2813	Specifically methylates the guanine in position
A1D33_RS08630	COG0250	Participates in transcription elongation, termination and antitermination
A1D33_RS08635	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A1D33_RS08645	COG1595	DNA-templated transcription, initiation
A1D33_RS08650	COG3688	RNA-binding protein containing a PIN domain
A1D33_RS08655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1D33_RS08660	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A1D33_RS08670	COG1045	serine acetyltransferase
A1D33_RS08690	COG4956	integral membrane protein (PIN domain superfamily)
A1D33_RS08695	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A1D33_RS08700	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A1D33_RS08705	COG0542	response to heat
A1D33_RS08715	COG3880	PFAM UvrB UvrC protein
A1D33_RS08720	COG4463	regulation of RNA biosynthetic process
A1D33_RS08740	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A1D33_RS08745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A1D33_RS08750	COG1396	sequence-specific DNA binding
A1D33_RS08755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A1D33_RS08760	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A1D33_RS08765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A1D33_RS08770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A1D33_RS08775	COG0512	Glutamine amidotransferase of anthranilate synthase
A1D33_RS08780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A1D33_RS08785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A1D33_RS08790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A1D33_RS08805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A1D33_RS08810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A1D33_RS08815	COG0037	tRNA processing
A1D33_RS08820	COG0515	serine threonine protein kinase
A1D33_RS08825	COG2304	oxidoreductase activity
A1D33_RS08830	COG2208	phosphoserine phosphatase activity
A1D33_RS08845	COG1098	S1 RNA binding domain
A1D33_RS08850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A1D33_RS08865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A1D33_RS08870	COG3956	TIGRFAM MazG family protein
A1D33_RS08875	COG2244	polysaccharide biosynthetic process
A1D33_RS08880	COG2002	toxin-antitoxin pair type II binding
A1D33_RS08885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A1D33_RS08905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A1D33_RS08920	COG0251	oxidation-reduction process
A1D33_RS08925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A1D33_RS08940	COG4466	Protein conserved in bacteria
A1D33_RS08950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A1D33_RS08955	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A1D33_RS08960	COG3583	domain protein
A1D33_RS08960	COG3584	3D domain protein
A1D33_RS08965	COG0084	hydrolase, TatD family'
A1D33_RS08970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A1D33_RS08970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A1D33_RS08975	COG2002	toxin-antitoxin pair type II binding
A1D33_RS08980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A1D33_RS08990	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A1D33_RS09000	COG1774	PSP1 C-terminal conserved region
A1D33_RS09005	COG0470	DNA polymerase III
A1D33_RS09010	COG1728	Protein conserved in bacteria
A1D33_RS09015	COG3870	Protein conserved in bacteria
A1D33_RS09025	COG1982	Orn Lys Arg decarboxylase major
A1D33_RS09030	COG3853	Toxic anion resistance protein (TelA)
A1D33_RS09035	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
A1D33_RS09070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A1D33_RS09075	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A1D33_RS09080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A1D33_RS09090	COG0590	tRNA wobble adenosine to inosine editing
A1D33_RS09095	COG1335	isochorismatase
A1D33_RS09100	COG3858	chitin binding
A1D33_RS09100	COG1388	LysM domain
A1D33_RS09105	COG1428	Deoxynucleoside kinase
A1D33_RS09110	COG1428	Deoxynucleoside kinase
A1D33_RS09120	COG1929	Belongs to the glycerate kinase type-1 family
A1D33_RS09140	COG1686	Belongs to the peptidase S11 family
A1D33_RS09145	COG0517	IMP dehydrogenase activity
A1D33_RS09145	COG0516	GMP reductase activity
A1D33_RS09170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A1D33_RS09175	COG0187	DNA topoisomerase II activity
A1D33_RS09190	COG2501	S4 domain
A1D33_RS09195	COG0592	DNA-directed DNA polymerase activity
A1D33_RS09215	COG0706	membrane insertase activity
A1D33_RS09220	COG1847	R3H domain protein
A1D33_RS09245	COG1192	Involved in chromosome partitioning
A1D33_RS09250	COG1475	DNA binding
A1D33_RS09265	COG3949	Membrane
A1D33_RS09270	COG4481	Protein conserved in bacteria
A1D33_RS09275	COG0243	molybdopterin cofactor binding
A1D33_RS09280	COG0012	GTP binding
A1D33_RS09290	COG0629	single-stranded DNA binding
A1D33_RS09300	COG2169	Transcriptional regulator
A1D33_RS09305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A1D33_RS09310	COG0708	Exodeoxyribonuclease III
A1D33_RS09315	COG1609	Transcriptional regulator
A1D33_RS09320	COG0346	lactoylglutathione lyase activity
A1D33_RS09325	COG0477	Major facilitator Superfamily
A1D33_RS09325	COG2814	Major facilitator Superfamily
A1D33_RS09330	COG1266	CAAX protease self-immunity
A1D33_RS09335	COG1331	Highly conserved protein containing a thioredoxin domain
A1D33_RS09340	COG0697	spore germination
A1D33_RS09345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A1D33_RS09350	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS09355	COG0583	DNA-binding transcription factor activity
A1D33_RS09360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1D33_RS09370	COG2153	protein acetylation
A1D33_RS09375	COG1846	Transcriptional regulator
A1D33_RS09380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A1D33_RS09385	COG1846	Transcriptional regulator
A1D33_RS09390	COG0778	Nitroreductase
A1D33_RS09405	COG0583	DNA-binding transcription factor activity
A1D33_RS09410	COG2211	Major facilitator Superfamily
A1D33_RS09415	COG2318	DinB family
A1D33_RS09420	COG1802	Transcriptional regulator
A1D33_RS09425	COG1621	beta-fructofuranosidase activity
A1D33_RS09430	COG1621	beta-fructofuranosidase activity
A1D33_RS09435	COG0697	spore germination
A1D33_RS09445	COG1733	regulation of RNA biosynthetic process
A1D33_RS09450	COG5577	PFAM Coat F domain
A1D33_RS09455	COG4241	membrane
A1D33_RS09460	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A1D33_RS09480	COG0438	transferase activity, transferring glycosyl groups
A1D33_RS09485	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A1D33_RS09500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A1D33_RS09515	COG0305	Participates in initiation and elongation during chromosome replication
A1D33_RS09520	COG0346	lactoylglutathione lyase activity
A1D33_RS09555	COG0745	RESPONSE REGULATOR receiver
A1D33_RS09560	COG5002	protein histidine kinase activity
A1D33_RS09565	COG4863	YycH protein
A1D33_RS09570	COG4853	Protein conserved in bacteria
A1D33_RS09575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A1D33_RS09580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1D33_RS09585	COG0745	RESPONSE REGULATOR receiver
A1D33_RS09590	COG3850	Histidine kinase
A1D33_RS09590	COG5002	protein histidine kinase activity
A1D33_RS09595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A1D33_RS09610	COG0488	(ABC) transporter
A1D33_RS09620	COG3829	transcription factor binding
A1D33_RS09625	COG0640	Transcriptional regulator
A1D33_RS09630	COG5658	integral membrane protein
A1D33_RS09635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A1D33_RS09640	COG0833	amino acid
A1D33_RS09645	COG0010	Belongs to the arginase family
A1D33_RS09650	COG0457	Tetratricopeptide repeat
A1D33_RS09655	COG0456	acetyltransferase
A1D33_RS09660	COG0667	Aldo Keto reductase
A1D33_RS09665	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
A1D33_RS09720	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A1D33_RS09725	COG2068	MobA-Related Protein
A1D33_RS09740	COG2080	2 iron, 2 sulfur cluster binding
A1D33_RS09750	COG1113	amino acid transport
A1D33_RS09755	COG3177	Filamentation induced by cAMP protein fic
A1D33_RS09760	COG3634	alkyl hydroperoxide reductase activity
A1D33_RS09765	COG0450	alkyl hydroperoxide reductase
A1D33_RS09770	COG1715	Restriction endonuclease
A1D33_RS09775	COG0501	Belongs to the peptidase M48B family
A1D33_RS09785	COG1714	RDD family
A1D33_RS09790	COG2814	Major facilitator Superfamily
A1D33_RS09795	COG0640	Transcriptional regulator
A1D33_RS09805	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1D33_RS09810	COG1012	belongs to the aldehyde dehydrogenase family
A1D33_RS09815	COG1309	transcriptional regulator
A1D33_RS09825	COG3239	Fatty acid desaturase
A1D33_RS09830	COG4585	Histidine kinase
A1D33_RS09835	COG2197	response regulator
A1D33_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS09855	COG2814	Major facilitator Superfamily
A1D33_RS09860	COG0667	Aldo Keto reductase
A1D33_RS09865	COG1349	DNA-binding transcription factor activity
A1D33_RS09895	COG2814	Major facilitator Superfamily
A1D33_RS09905	COG1082	Xylose isomerase domain protein TIM barrel
A1D33_RS09935	COG0745	RESPONSE REGULATOR receiver
A1D33_RS09940	COG2205	protein histidine kinase activity
A1D33_RS09945	COG0745	RESPONSE REGULATOR receiver
A1D33_RS09950	COG2205	protein histidine kinase activity
A1D33_RS09955	COG1136	(ABC) transporter
A1D33_RS09960	COG0577	efflux transmembrane transporter activity
A1D33_RS09965	COG5294	Protein conserved in bacteria
A1D33_RS09970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1D33_RS10000	COG0561	phosphatase activity
A1D33_RS10005	COG2390	Transcriptional regulator
A1D33_RS10015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A1D33_RS10020	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A1D33_RS10025	COG0833	amino acid
A1D33_RS10030	COG0010	Belongs to the arginase family
A1D33_RS10055	COG3507	Belongs to the glycosyl hydrolase 43 family
A1D33_RS10065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D33_RS10065	COG1263	PTS System
A1D33_RS10065	COG2190	(PTS) system
A1D33_RS10070	COG2723	6-phospho-beta-galactosidase activity
A1D33_RS10075	COG0589	response to stress
A1D33_RS10080	COG0697	spore germination
A1D33_RS10090	COG3209	COG3209 Rhs family protein
A1D33_RS10140	COG0513	Belongs to the DEAD box helicase family
A1D33_RS10145	COG2270	Major facilitator Superfamily
A1D33_RS10150	COG3711	transcriptional antiterminator
A1D33_RS10155	COG2273	Hydrolase Family 16
A1D33_RS10160	COG2851	Citrate transporter
A1D33_RS10165	COG0693	protein deglycase activity
A1D33_RS10165	COG0753	catalase activity
A1D33_RS10180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A1D33_RS10185	COG0500	methyltransferase
A1D33_RS10190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A1D33_RS10195	COG4894	glucomannan catabolic process
A1D33_RS10205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A1D33_RS10215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A1D33_RS10220	COG2508	Transcriptional regulator
A1D33_RS10225	COG3842	ATPase activity
A1D33_RS10230	COG0726	polysaccharide deacetylase
A1D33_RS10235	COG3493	citrate carrier protein
A1D33_RS10240	COG1271	oxidase subunit
A1D33_RS10245	COG1294	oxidase, subunit
A1D33_RS10250	COG4988	ABC transporter
A1D33_RS10255	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A1D33_RS10260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A1D33_RS10265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A1D33_RS10270	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A1D33_RS10275	COG0753	catalase activity
A1D33_RS10285	COG1482	cell wall glycoprotein biosynthetic process
A1D33_RS10290	COG1940	carbohydrate kinase activity
A1D33_RS10295	COG2723	6-phospho-beta-galactosidase activity
A1D33_RS10300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1D33_RS10305	COG1447	Phosphotransferase system cellobiose-specific component IIA
A1D33_RS10310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1D33_RS10315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A1D33_RS10320	COG0640	Transcriptional regulator
A1D33_RS10330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D33_RS10335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D33_RS10345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D33_RS10345	COG3711	transcriptional antiterminator
A1D33_RS10350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1D33_RS10355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1D33_RS10360	COG1447	Phosphotransferase system cellobiose-specific component IIA
A1D33_RS10365	COG1486	melibiose metabolic process
A1D33_RS10370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A1D33_RS10375	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A1D33_RS10385	COG1696	Membrane protein involved in D-alanine export
A1D33_RS10400	COG1575	Belongs to the MenA family. Type 1 subfamily
A1D33_RS10405	COG2357	RelA SpoT domain protein
A1D33_RS10415	COG1442	glycosyl transferase family 8
A1D33_RS10420	COG1404	Belongs to the peptidase S8 family
A1D33_RS10425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1D33_RS10430	COG0346	lactoylglutathione lyase activity
A1D33_RS10435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A1D33_RS10440	COG5504	Zn-dependent protease
A1D33_RS10445	COG0789	Transcriptional regulator
A1D33_RS10450	COG4895	conserved protein (DUF2196)
A1D33_RS10455	COG1346	cytolysis
A1D33_RS10465	COG0583	DNA-binding transcription factor activity
A1D33_RS10480	COG2822	iron ion transport
A1D33_RS10485	COG2837	iron assimilation
A1D33_RS10490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A1D33_RS10510	COG1309	transcriptional regulator
A1D33_RS10515	COG2246	polysaccharide biosynthetic process
A1D33_RS10525	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A1D33_RS10530	COG2261	transglycosylase associated protein
A1D33_RS10535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A1D33_RS10540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A1D33_RS10560	COG0454	-acetyltransferase
A1D33_RS10565	COG0772	Belongs to the SEDS family
A1D33_RS10570	COG0778	Nitroreductase
A1D33_RS10575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A1D33_RS10580	COG1404	Belongs to the peptidase S8 family
A1D33_RS10590	COG3711	transcriptional antiterminator
A1D33_RS10595	COG1263	PTS System
A1D33_RS10595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D33_RS10600	COG1621	beta-fructofuranosidase activity
A1D33_RS10610	COG0351	phosphomethylpyrimidine kinase
A1D33_RS10615	COG1216	Glycosyl transferase, family 2
A1D33_RS10630	COG2233	PERMEase
A1D33_RS10635	COG2363	Small membrane protein
A1D33_RS10645	COG0463	Glycosyl transferase, family 2
A1D33_RS10650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A1D33_RS10655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A1D33_RS10660	COG0456	acetyltransferase
A1D33_RS10665	COG2089	acid synthase
A1D33_RS10670	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
A1D33_RS10675	COG3980	spore coat polysaccharide biosynthesis protein
A1D33_RS10680	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A1D33_RS10685	COG1088	dTDP-glucose 4,6-dehydratase activity
A1D33_RS10690	COG1091	dTDP-4-dehydrorhamnose reductase activity
A1D33_RS10695	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A1D33_RS10705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A1D33_RS10710	COG1012	belongs to the aldehyde dehydrogenase family
A1D33_RS10715	COG4187	Peptidase family M20/M25/M40
A1D33_RS10720	COG0833	amino acid
A1D33_RS10725	COG2814	Major facilitator Superfamily
A1D33_RS10730	COG2814	Major facilitator Superfamily
A1D33_RS10760	COG0436	Aminotransferase
A1D33_RS10765	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS10775	COG0280	phosphate acetyltransferase
A1D33_RS10780	COG2855	membrane
A1D33_RS10785	COG0583	DNA-binding transcription factor activity
A1D33_RS10815	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A1D33_RS10820	COG1131	(ABC) transporter
A1D33_RS10830	COG1695	Transcriptional regulator
A1D33_RS10845	COG1078	dGTPase activity
A1D33_RS10850	COG3465	dGTPase activity
A1D33_RS10855	COG0531	amino acid
A1D33_RS10860	COG1846	Transcriptional regulator
A1D33_RS10865	COG1942	4-Oxalocrotonate Tautomerase
A1D33_RS10870	COG1994	Peptidase M50
A1D33_RS10885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A1D33_RS10890	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A1D33_RS10895	COG0010	Belongs to the arginase family
A1D33_RS10940	COG0457	Tetratricopeptide repeat
A1D33_RS10945	COG3391	amine dehydrogenase activity
A1D33_RS10960	COG4506	Protein conserved in bacteria
A1D33_RS10970	COG2223	nitrite transmembrane transporter activity
A1D33_RS10975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A1D33_RS10985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A1D33_RS10990	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A1D33_RS10995	COG1140	nitrate reductase beta subunit
A1D33_RS11000	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A1D33_RS11005	COG2181	nitrate reductase activity
A1D33_RS11015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A1D33_RS11020	COG1132	(ABC) transporter
A1D33_RS11035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A1D33_RS11040	COG2181	nitrate reductase activity
A1D33_RS11040	COG0247	lactate metabolic process
A1D33_RS11055	COG4821	SIS domain
A1D33_RS11060	COG2204	response regulator
A1D33_RS11065	COG0191	fructose-bisphosphate aldolase activity
A1D33_RS11075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A1D33_RS11080	COG1494	fructose-1,6-bisphosphatase
A1D33_RS11085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A1D33_RS11100	COG0281	malic enzyme
A1D33_RS11105	COG0679	Auxin Efflux Carrier
A1D33_RS11110	COG0789	Transcriptional regulator
A1D33_RS11115	COG0346	lactoylglutathione lyase activity
A1D33_RS11120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A1D33_RS11125	COG2890	protein-(glutamine-N5) methyltransferase activity
A1D33_RS11145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A1D33_RS11150	COG0009	L-threonylcarbamoyladenylate synthase
A1D33_RS11160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A1D33_RS11165	COG0698	ribose 5-phosphate isomerase
A1D33_RS11235	COG4836	Membrane
A1D33_RS11245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A1D33_RS11250	COG2385	sporulation resulting in formation of a cellular spore
A1D33_RS11255	COG2304	oxidoreductase activity
A1D33_RS11260	COG2304	oxidoreductase activity
A1D33_RS11265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A1D33_RS11275	COG0457	Tetratricopeptide repeat
A1D33_RS11280	COG1994	Peptidase M50
A1D33_RS11290	COG0831	urea catabolic process
A1D33_RS11305	COG1959	2 iron, 2 sulfur cluster binding
A1D33_RS11310	COG0726	polysaccharide deacetylase
A1D33_RS11325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A1D33_RS11340	COG1247	-acetyltransferase
A1D33_RS11345	COG0739	heme binding
A1D33_RS11355	COG0671	phosphoesterase, PA-phosphatase related
A1D33_RS11360	COG0772	Belongs to the SEDS family
A1D33_RS11365	COG0347	Belongs to the P(II) protein family
A1D33_RS11370	COG0004	ammonium transporteR
A1D33_RS11375	COG1335	isochorismatase
A1D33_RS11380	COG0477	Major facilitator Superfamily
A1D33_RS11385	COG1953	Uracil, thiamine, allantoin
A1D33_RS11390	COG2814	Major facilitator Superfamily
A1D33_RS11395	COG1846	Transcriptional regulator
A1D33_RS11400	COG1609	Transcriptional regulator
A1D33_RS11405	COG1077	Cell shape determining protein MreB Mrl
A1D33_RS11410	COG4786	Flagellar basal body rod
A1D33_RS11415	COG4786	Flagellar basal body rod
A1D33_RS11420	COG0457	Tetratricopeptide repeat
A1D33_RS11445	COG0629	single-stranded DNA binding
A1D33_RS11450	COG1349	DNA-binding transcription factor activity
A1D33_RS11455	COG0561	phosphatase activity
A1D33_RS11460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A1D33_RS11465	COG4715	Zinc finger, swim domain protein
A1D33_RS11475	COG3944	biosynthesis protein
A1D33_RS11480	COG0489	protein tyrosine kinase activity
A1D33_RS11485	COG4464	protein tyrosine phosphatase activity
A1D33_RS11490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A1D33_RS11495	COG3878	Protein conserved in bacteria
A1D33_RS11510	COG5444	nuclease activity
A1D33_RS11520	COG2801	Transposase and inactivated derivatives
A1D33_RS11565	COG2059	Chromate
A1D33_RS11570	COG2059	Chromate
A1D33_RS11575	COG1522	sequence-specific DNA binding
A1D33_RS11580	COG0405	Gamma-glutamyltransferase
A1D33_RS11590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A1D33_RS11600	COG5337	Spore coat protein CotH
A1D33_RS11615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A1D33_RS11620	COG0583	DNA-binding transcription factor activity
A1D33_RS11625	COG0028	Belongs to the TPP enzyme family
A1D33_RS11630	COG3527	Alpha-acetolactate decarboxylase
A1D33_RS11635	COG2249	NAD(P)H dehydrogenase (quinone) activity
A1D33_RS11640	COG3103	Sh3 type 3 domain protein
A1D33_RS11645	COG1879	ABC-type sugar transport system periplasmic component
A1D33_RS11650	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1D33_RS11655	COG1129	ABC transporter
A1D33_RS11665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D33_RS11670	COG1609	Transcriptional regulator
A1D33_RS11680	COG0814	amino acid
A1D33_RS11685	COG0697	spore germination
A1D33_RS11690	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A1D33_RS11700	COG2843	Capsule synthesis protein
A1D33_RS11705	COG0791	NLP P60 protein
A1D33_RS11710	COG2433	Pfam Transposase IS66
A1D33_RS11715	COG0561	phosphatase activity
A1D33_RS11720	COG1316	TRANSCRIPTIONal
A1D33_RS11725	COG2814	Major facilitator Superfamily
A1D33_RS11730	COG1215	transferase activity, transferring glycosyl groups
A1D33_RS11740	COG0814	amino acid
A1D33_RS11745	COG0697	spore germination
A1D33_RS11750	COG1482	cell wall glycoprotein biosynthetic process
A1D33_RS11755	COG4193	domain, Protein
A1D33_RS11760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A1D33_RS11765	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A1D33_RS11770	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A1D33_RS11780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A1D33_RS11785	COG1682	transport, permease protein
A1D33_RS11790	COG1134	teichoic acid transport
A1D33_RS11795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A1D33_RS11800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A1D33_RS11805	COG1316	TRANSCRIPTIONal
A1D33_RS11815	COG2385	sporulation resulting in formation of a cellular spore
A1D33_RS11815	COG2247	cell wall binding repeat
A1D33_RS11820	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS11820	COG2247	cell wall binding repeat
A1D33_RS11830	COG2244	polysaccharide biosynthetic process
A1D33_RS11835	COG0297	glycogen (starch) synthase activity
A1D33_RS11835	COG0438	transferase activity, transferring glycosyl groups
A1D33_RS11840	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A1D33_RS11845	COG3307	-O-antigen
A1D33_RS11850	COG3206	protein involved in exopolysaccharide biosynthesis
A1D33_RS11855	COG1215	transferase activity, transferring glycosyl groups
A1D33_RS11860	COG0438	transferase activity, transferring glycosyl groups
A1D33_RS11865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A1D33_RS11870	COG1316	TRANSCRIPTIONal
A1D33_RS11875	COG1739	Uncharacterized protein family UPF0029
A1D33_RS11880	COG4585	Histidine kinase
A1D33_RS11885	COG2197	response regulator
A1D33_RS11890	COG1307	EDD domain protein, DegV family
A1D33_RS11895	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A1D33_RS11905	COG1040	competence protein
A1D33_RS11915	COG2747	anti-sigma28 factor FlgM
A1D33_RS11920	COG3418	PFAM FlgN family protein
A1D33_RS11925	COG4786	Flagellar basal body rod
A1D33_RS11925	COG1256	bacterial-type flagellum assembly
A1D33_RS11930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A1D33_RS11950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A1D33_RS11955	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A1D33_RS11960	COG1516	flagellar protein fliS
A1D33_RS11975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A1D33_RS11985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A1D33_RS11990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A1D33_RS11995	COG2010	Cytochrome c
A1D33_RS12000	COG2884	Cell division ATP-binding protein ftsE
A1D33_RS12005	COG2177	Part of the ABC transporter FtsEX involved in
A1D33_RS12010	COG3420	alginic acid biosynthetic process
A1D33_RS12015	COG3409	Peptidoglycan-binding domain 1 protein
A1D33_RS12015	COG0793	Belongs to the peptidase S41A family
A1D33_RS12025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1D33_RS12070	COG2814	Major facilitator Superfamily
A1D33_RS12075	COG1309	transcriptional regulator
A1D33_RS12080	COG3848	Pyruvate phosphate dikinase
A1D33_RS12080	COG0574	Belongs to the PEP-utilizing enzyme family
A1D33_RS12085	COG4897	Protein conserved in bacteria
A1D33_RS12095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A1D33_RS12110	COG3595	metallopeptidase activity
A1D33_RS12115	COG1983	PspC domain protein
A1D33_RS12120	COG1950	PFAM Membrane protein of
A1D33_RS12125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A1D33_RS12130	COG1309	transcriptional regulator
A1D33_RS12135	COG2188	Transcriptional regulator
A1D33_RS12145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A1D33_RS12165	COG0110	maltose O-acetyltransferase activity
A1D33_RS12170	COG4990	cell redox homeostasis
A1D33_RS12185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A1D33_RS12210	COG0140	phosphoribosyl-ATP diphosphatase activity
A1D33_RS12210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A1D33_RS12215	COG1132	(ABC) transporter
A1D33_RS12225	COG0745	RESPONSE REGULATOR receiver
A1D33_RS12230	COG5002	protein histidine kinase activity
A1D33_RS12235	COG0457	Tetratricopeptide repeat
A1D33_RS12240	COG3883	PFAM NLP P60 protein
A1D33_RS12240	COG0791	NLP P60 protein
A1D33_RS12245	COG0492	ferredoxin-NADP+ reductase activity
A1D33_RS12250	COG1051	belongs to the nudix hydrolase family
A1D33_RS12260	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A1D33_RS12270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D33_RS12275	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A1D33_RS12280	COG4290	ribonuclease
A1D33_RS12285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A1D33_RS12295	COG0288	reversible hydration of carbon dioxide
A1D33_RS12300	COG0659	secondary active sulfate transmembrane transporter activity
A1D33_RS12305	COG1694	Mazg nucleotide pyrophosphohydrolase
A1D33_RS12310	COG1611	Belongs to the LOG family
A1D33_RS12315	COG0477	Major facilitator Superfamily
A1D33_RS12315	COG2814	Major facilitator Superfamily
A1D33_RS12320	COG2828	Protein conserved in bacteria
A1D33_RS12325	COG0583	DNA-binding transcription factor activity
A1D33_RS12335	COG1609	Transcriptional regulator
A1D33_RS12340	COG2211	Major facilitator Superfamily
A1D33_RS12390	COG3479	Phenolic acid decarboxylase
A1D33_RS12395	COG0456	acetyltransferase
A1D33_RS12400	COG2364	Membrane
A1D33_RS12405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A1D33_RS12410	COG2272	Belongs to the type-B carboxylesterase lipase family
A1D33_RS12415	COG1396	sequence-specific DNA binding
A1D33_RS12420	COG3944	biosynthesis protein
A1D33_RS12425	COG0489	protein tyrosine kinase activity
A1D33_RS12430	COG1086	Polysaccharide biosynthesis protein
A1D33_RS12435	COG0438	transferase activity, transferring glycosyl groups
A1D33_RS12440	COG1215	transferase activity, transferring glycosyl groups
A1D33_RS12445	COG0438	transferase activity, transferring glycosyl groups
A1D33_RS12455	COG1216	Glycosyl transferase, family 2
A1D33_RS12460	COG5039	Polysaccharide pyruvyl transferase
A1D33_RS12465	COG1216	Glycosyl transferase, family 2
A1D33_RS12470	COG2244	polysaccharide biosynthetic process
A1D33_RS12475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A1D33_RS12480	COG0110	maltose O-acetyltransferase activity
A1D33_RS12485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A1D33_RS12490	COG5039	Polysaccharide pyruvyl transferase
A1D33_RS12500	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A1D33_RS12505	COG1620	l-lactate permease
A1D33_RS12510	COG2186	Transcriptional regulator
A1D33_RS12515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A1D33_RS12540	COG1070	Carbohydrate kinase
A1D33_RS12545	COG1737	Transcriptional regulator
A1D33_RS12550	COG0561	phosphatase activity
A1D33_RS12560	COG1609	Transcriptional regulator
A1D33_RS12570	COG1113	amino acid transport
A1D33_RS12575	COG0697	spore germination
A1D33_RS12580	COG0583	DNA-binding transcription factor activity
A1D33_RS12590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A1D33_RS12595	COG1609	Transcriptional regulator
A1D33_RS12600	COG2814	Major facilitator Superfamily
A1D33_RS12605	COG2390	Transcriptional regulator
A1D33_RS12610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A1D33_RS12620	COG0126	phosphoglycerate kinase activity
A1D33_RS12640	COG2234	aminopeptidase activity
A1D33_RS12650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A1D33_RS12655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D33_RS12675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A1D33_RS12690	COG0456	acetyltransferase
A1D33_RS12695	COG4640	response to antibiotic
A1D33_RS12700	COG3064	Membrane
A1D33_RS12705	COG2095	MarC family integral membrane protein
A1D33_RS12710	COG1510	regulation of RNA biosynthetic process
A1D33_RS12715	COG0517	IMP dehydrogenase activity
A1D33_RS12715	COG1125	glycine betaine transport
A1D33_RS12720	COG1174	glycine betaine transport
A1D33_RS12725	COG1732	Glycine betaine
A1D33_RS12730	COG1174	glycine betaine transport
A1D33_RS12735	COG1510	regulation of RNA biosynthetic process
A1D33_RS12740	COG1125	glycine betaine transport
A1D33_RS12740	COG0517	IMP dehydrogenase activity
A1D33_RS12745	COG1174	glycine betaine transport
A1D33_RS12750	COG1732	Glycine betaine
A1D33_RS12755	COG1174	glycine betaine transport
A1D33_RS12760	COG1131	(ABC) transporter
A1D33_RS12785	COG1733	regulation of RNA biosynthetic process
A1D33_RS12790	COG1396	sequence-specific DNA binding
A1D33_RS12795	COG1396	sequence-specific DNA binding
A1D33_RS12800	COG1476	TRANSCRIPTIONal
A1D33_RS12805	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A1D33_RS12810	COG1647	Serine aminopeptidase, S33
A1D33_RS12815	COG0557	exoribonuclease II activity
A1D33_RS12830	COG2732	(Barnase) inhibitor
A1D33_RS12835	COG2732	(Barnase) inhibitor
A1D33_RS12840	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS12845	COG0583	DNA-binding transcription factor activity
A1D33_RS12855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D33_RS12860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D33_RS12865	COG0765	amino acid transport
A1D33_RS12870	COG0765	amino acid transport
A1D33_RS12875	COG1126	abc transporter atp-binding protein
A1D33_RS12880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A1D33_RS12885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A1D33_RS12890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A1D33_RS12905	COG2814	Major facilitator Superfamily
A1D33_RS12920	COG0673	inositol 2-dehydrogenase activity
A1D33_RS12925	COG1937	Protein conserved in bacteria
A1D33_RS12930	COG2608	mercury ion transmembrane transporter activity
A1D33_RS12935	COG2217	Heavy metal translocating P-type atpase
A1D33_RS12940	COG2217	Heavy metal translocating P-type atpase
A1D33_RS12945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A1D33_RS12950	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A1D33_RS12960	COG2860	membrane
A1D33_RS12965	COG3973	AAA domain
A1D33_RS12970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A1D33_RS12995	COG0656	L-ascorbic acid biosynthetic process
A1D33_RS13000	COG0842	Transport permease protein
A1D33_RS13010	COG1131	(ABC) transporter
A1D33_RS13015	COG3850	Histidine kinase
A1D33_RS13020	COG2197	response regulator
A1D33_RS13025	COG4149	molybdate abc transporter
A1D33_RS13030	COG0725	ABC transporter, periplasmic molybdate-binding protein
A1D33_RS13035	COG1910	domain protein
A1D33_RS13040	COG1368	sulfuric ester hydrolase activity
A1D33_RS13045	COG1988	membrane-bound metal-dependent
A1D33_RS13055	COG0531	amino acid
A1D33_RS13060	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A1D33_RS13065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1D33_RS13070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D33_RS13075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D33_RS13080	COG1120	ATPase activity
A1D33_RS13090	COG2140	Oxalate decarboxylase
A1D33_RS13095	COG1191	sigma factor activity
A1D33_RS13105	COG0745	RESPONSE REGULATOR receiver
A1D33_RS13110	COG2205	protein histidine kinase activity
A1D33_RS13115	COG3386	PFAM SMP-30 Gluconolaconase
A1D33_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS13125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1D33_RS13130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D33_RS13135	COG1120	ATPase activity
A1D33_RS13140	COG2096	Adenosyltransferase
A1D33_RS13145	COG2814	Major facilitator Superfamily
A1D33_RS13150	COG4758	membrane
A1D33_RS13155	COG1842	Phage shock protein A
A1D33_RS13160	COG3595	metallopeptidase activity
A1D33_RS13165	COG4758	membrane
A1D33_RS13170	COG4585	Histidine kinase
A1D33_RS13175	COG2197	response regulator
A1D33_RS13185	COG0814	amino acid
A1D33_RS13190	COG0697	spore germination
A1D33_RS13200	COG0114	fumarate hydratase activity
A1D33_RS13205	COG1309	transcriptional regulator
A1D33_RS13210	COG2770	Histidine kinase
A1D33_RS13210	COG2205	protein histidine kinase activity
A1D33_RS13215	COG0745	RESPONSE REGULATOR receiver
A1D33_RS13220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1D33_RS13225	COG0783	Belongs to the Dps family
A1D33_RS13230	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS13245	COG1120	ATPase activity
A1D33_RS13265	COG0583	DNA-binding transcription factor activity
A1D33_RS13270	COG0477	Major facilitator Superfamily
A1D33_RS13275	COG1846	Transcriptional regulator
A1D33_RS13280	COG5577	PFAM Coat F domain
A1D33_RS13290	COG0477	Major facilitator Superfamily
A1D33_RS13305	COG1250	3-hydroxyacyl-CoA dehydrogenase
A1D33_RS13305	COG1024	Enoyl-CoA hydratase
A1D33_RS13310	COG0183	Belongs to the thiolase family
A1D33_RS13315	COG1960	acyl-CoA dehydrogenase activity
A1D33_RS13320	COG1393	Belongs to the ArsC family
A1D33_RS13335	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A1D33_RS13340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS13350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A1D33_RS13355	COG2011	ABC-type metal ion transport system permease component
A1D33_RS13360	COG1464	Belongs to the NlpA lipoprotein family
A1D33_RS13365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1D33_RS13370	COG0396	ATPase activity
A1D33_RS13375	COG0719	Fe-S assembly protein
A1D33_RS13380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A1D33_RS13385	COG0822	iron-sulfur transferase activity
A1D33_RS13390	COG0719	Fe-S assembly protein
A1D33_RS13400	COG2801	Transposase and inactivated derivatives
A1D33_RS13405	COG3409	Peptidoglycan-binding domain 1 protein
A1D33_RS13415	COG2226	methyltransferase
A1D33_RS13420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A1D33_RS13425	COG0322	excinuclease ABC activity
A1D33_RS13450	COG0789	Transcriptional regulator
A1D33_RS13455	COG2222	sugar isomerase
A1D33_RS13460	COG1653	transport
A1D33_RS13465	COG1175	transmembrane transport
A1D33_RS13470	COG0395	ABC-type sugar transport system, permease component
A1D33_RS13475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D33_RS13480	COG2188	Transcriptional regulator
A1D33_RS13485	COG3842	ATPase activity
A1D33_RS13490	COG2356	endonuclease I
A1D33_RS13495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A1D33_RS13500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A1D33_RS13505	COG2814	Major facilitator Superfamily
A1D33_RS13515	COG2508	Transcriptional regulator
A1D33_RS13530	COG1801	Protein of unknown function DUF72
A1D33_RS13535	COG0730	response to heat
A1D33_RS13540	COG0737	Belongs to the 5'-nucleotidase family
A1D33_RS13550	COG0739	heme binding
A1D33_RS13560	COG4470	Protein conserved in bacteria
A1D33_RS13565	COG2445	Protein of unknown function DUF86
A1D33_RS13570	COG0647	UMP catabolic process
A1D33_RS13575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A1D33_RS13580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A1D33_RS13585	COG0460	homoserine dehydrogenase
A1D33_RS13590	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A1D33_RS13600	COG1506	peptidase
A1D33_RS13600	COG4946	Tricorn protease homolog
A1D33_RS13600	COG0823	Involved in the tonB-independent uptake of proteins
A1D33_RS13605	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A1D33_RS13610	COG4837	Protein of unknown function (DUF1462)
A1D33_RS13615	COG1252	NADH dehydrogenase
A1D33_RS13625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A1D33_RS13635	COG0316	Belongs to the HesB IscA family
A1D33_RS13645	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A1D33_RS13650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1D33_RS13670	COG1131	(ABC) transporter
A1D33_RS13700	COG1252	NADH dehydrogenase
A1D33_RS13710	COG3584	3D domain protein
A1D33_RS13715	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A1D33_RS13725	COG2056	Na+-H+ antiporter family
A1D33_RS13730	COG1268	BioY protein
A1D33_RS13735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A1D33_RS13740	COG2819	hydrolase of the alpha beta superfamily
A1D33_RS13745	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS13750	COG1169	isochorismate synthase
A1D33_RS13755	COG1021	2,3-dihydroxybenzoate-AMP ligase
A1D33_RS13760	COG1535	isochorismatase
A1D33_RS13760	COG3433	isochorismatase activity
A1D33_RS13765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS13770	COG3251	PFAM MbtH domain protein
A1D33_RS13775	COG5634	Uncharacterized conserved protein (DUF2278)
A1D33_RS13780	COG0686	Belongs to the AlaDH PNT family
A1D33_RS13785	COG2508	Transcriptional regulator
A1D33_RS13785	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A1D33_RS13790	COG4842	Belongs to the WXG100 family
A1D33_RS13795	COG5417	Belongs to the EsaB family
A1D33_RS13800	COG4499	WXG100 protein secretion system (Wss), protein YukC
A1D33_RS13805	COG1674	ftsk spoiiie
A1D33_RS13805	COG0433	COG0433 Predicted ATPase
A1D33_RS13810	COG1511	domain protein
A1D33_RS13820	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS13825	COG1418	mRNA catabolic process
A1D33_RS13835	COG0628	permease
A1D33_RS13850	COG5506	Protein of unknown function (DUF1694)
A1D33_RS13855	COG1335	isochorismatase
A1D33_RS13860	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A1D33_RS13865	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A1D33_RS13880	COG0142	geranyltranstransferase activity
A1D33_RS13890	COG4585	Histidine kinase
A1D33_RS13895	COG2197	response regulator
A1D33_RS13900	COG2050	protein possibly involved in aromatic compounds catabolism
A1D33_RS13905	COG1320	monovalent cation:proton antiporter activity
A1D33_RS13910	COG2212	antiporter activity
A1D33_RS13915	COG1863	multisubunit Na H antiporter MnhE subunit
A1D33_RS13920	COG0651	ATP synthesis coupled electron transport
A1D33_RS13925	COG1006	Multisubunit Na H antiporter MnhC subunit
A1D33_RS13930	COG2111	Na H antiporter
A1D33_RS13935	COG2111	Na H antiporter
A1D33_RS13935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A1D33_RS13945	COG1079	Belongs to the binding-protein-dependent transport system permease family
A1D33_RS13950	COG4603	Belongs to the binding-protein-dependent transport system permease family
A1D33_RS13955	COG3845	ABC transporter
A1D33_RS13960	COG1744	ABC transporter substrate-binding protein PnrA-like
A1D33_RS13965	COG4565	transcriptional regulatory protein
A1D33_RS13970	COG3290	protein histidine kinase activity
A1D33_RS13980	COG3011	Protein conserved in bacteria
A1D33_RS13985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A1D33_RS13990	COG2814	Major facilitator Superfamily
A1D33_RS13995	COG5018	Exonuclease
A1D33_RS14010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A1D33_RS14020	COG2267	carboxylic ester hydrolase activity
A1D33_RS14025	COG1522	sequence-specific DNA binding
A1D33_RS14030	COG0436	Aminotransferase
A1D33_RS14035	COG1098	S1 RNA binding domain
A1D33_RS14040	COG2155	Conserved Protein
A1D33_RS14045	COG1979	alcohol dehydrogenase
A1D33_RS14050	COG1979	alcohol dehydrogenase
A1D33_RS14055	COG1335	isochorismatase
A1D33_RS14085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A1D33_RS14100	COG2738	Putative neutral zinc metallopeptidase
A1D33_RS14105	COG1253	flavin adenine dinucleotide binding
A1D33_RS14110	COG0366	Alpha amylase catalytic
A1D33_RS14115	COG0432	Pfam Uncharacterised protein family UPF0047
A1D33_RS14120	COG2070	2-Nitropropane dioxygenase
A1D33_RS14135	COG0840	transmembrane signaling receptor activity
A1D33_RS14140	COG0840	transmembrane signaling receptor activity
A1D33_RS14145	COG0840	transmembrane signaling receptor activity
A1D33_RS14150	COG0840	transmembrane signaling receptor activity
A1D33_RS14155	COG0693	protein deglycase activity
A1D33_RS14160	COG0673	inositol 2-dehydrogenase activity
A1D33_RS14165	COG0628	permease
A1D33_RS14190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1D33_RS14190	COG1017	nitric oxide dioxygenase activity
A1D33_RS14195	COG1705	Flagellar rod assembly protein muramidase FlgJ
A1D33_RS14200	COG0569	domain protein
A1D33_RS14210	COG1510	regulation of RNA biosynthetic process
A1D33_RS14215	COG1012	belongs to the aldehyde dehydrogenase family
A1D33_RS14220	COG1454	alcohol dehydrogenase
A1D33_RS14230	COG2318	DinB family
A1D33_RS14235	COG1585	Membrane protein implicated in regulation of membrane protease activity
A1D33_RS14240	COG2268	Band 7 protein
A1D33_RS14245	COG3859	Proton-coupled thiamine transporter YuaJ
A1D33_RS14370	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A1D33_RS14375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A1D33_RS14380	COG1169	isochorismate synthase
A1D33_RS14390	COG0596	Alpha beta hydrolase
A1D33_RS14395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A1D33_RS14405	COG4948	Mandelate Racemase Muconate Lactonizing
A1D33_RS14410	COG1294	oxidase, subunit
A1D33_RS14415	COG1271	oxidase subunit
A1D33_RS14425	COG0288	reversible hydration of carbon dioxide
A1D33_RS14450	COG0783	Belongs to the Dps family
A1D33_RS14455	COG4824	toxin secretion phage lysis holin
A1D33_RS14460	COG0494	nUDIX hydrolase
A1D33_RS14465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A1D33_RS14470	COG1116	anion transmembrane transporter activity
A1D33_RS14475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A1D33_RS14480	COG1506	peptidase
A1D33_RS14500	COG0367	asparagine synthase
A1D33_RS14505	COG1113	amino acid transport
A1D33_RS14510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A1D33_RS14515	COG2267	carboxylic ester hydrolase activity
A1D33_RS14525	COG0584	glycerophosphoryl diester phosphodiesterase
A1D33_RS14535	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A1D33_RS14540	COG1242	4 iron, 4 sulfur cluster binding
A1D33_RS14545	COG0477	Major facilitator Superfamily
A1D33_RS14550	COG0640	Transcriptional regulator
A1D33_RS14560	COG1725	Transcriptional regulator
A1D33_RS14565	COG1131	(ABC) transporter
A1D33_RS14585	COG1136	(ABC) transporter
A1D33_RS14590	COG0577	efflux transmembrane transporter activity
A1D33_RS14595	COG0745	RESPONSE REGULATOR receiver
A1D33_RS14600	COG2205	protein histidine kinase activity
A1D33_RS14605	COG1136	(ABC) transporter
A1D33_RS14610	COG0577	efflux transmembrane transporter activity
A1D33_RS14615	COG5522	Integral membrane protein (intg_mem_TP0381)
A1D33_RS14620	COG2814	Major facilitator Superfamily
A1D33_RS14625	COG1366	Belongs to the anti-sigma-factor antagonist family
A1D33_RS14625	COG2202	Pas domain
A1D33_RS14640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A1D33_RS14650	COG1486	melibiose metabolic process
A1D33_RS14655	COG0395	ABC-type sugar transport system, permease component
A1D33_RS14660	COG1175	transmembrane transport
A1D33_RS14665	COG1653	transport
A1D33_RS14670	COG1609	Transcriptional regulator
A1D33_RS14680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A1D33_RS14685	COG2081	HI0933 family
A1D33_RS14690	COG2244	polysaccharide biosynthetic process
A1D33_RS14695	COG1187	pseudouridine synthase activity
A1D33_RS14700	COG1349	DNA-binding transcription factor activity
A1D33_RS14705	COG1131	(ABC) transporter
A1D33_RS14710	COG4473	ABC transporter
A1D33_RS14715	COG2252	PERMEase
A1D33_RS14720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A1D33_RS14725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A1D33_RS14730	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A1D33_RS14740	COG1597	lipid kinase activity
A1D33_RS14745	COG0510	thiamine kinase activity
A1D33_RS14760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1D33_RS14765	COG0281	malic enzyme
A1D33_RS14770	COG5584	Small secreted protein
A1D33_RS14775	COG1363	Peptidase, m42
A1D33_RS14785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS14795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A1D33_RS14800	COG1674	ftsk spoiiie
A1D33_RS14810	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A1D33_RS14815	COG4980	gas vesicle protein
A1D33_RS14820	COG3118	belongs to the thioredoxin family
A1D33_RS14825	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A1D33_RS14825	COG1605	Chorismate mutase
A1D33_RS14830	COG1609	Transcriptional regulator
A1D33_RS14835	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A1D33_RS14840	COG1360	Flagellar Motor Protein
A1D33_RS14845	COG0123	including yeast histone deacetylase and acetoin utilization protein
A1D33_RS14850	COG0517	IMP dehydrogenase activity
A1D33_RS14855	COG0454	-acetyltransferase
A1D33_RS14860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A1D33_RS14880	COG1378	Sugar-specific transcriptional regulator TrmB
A1D33_RS14885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A1D33_RS14895	COG0693	protein deglycase activity
A1D33_RS14905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1D33_RS14905	COG1017	nitric oxide dioxygenase activity
A1D33_RS14910	COG4282	regulation of fungal-type cell wall biogenesis
A1D33_RS14915	COG1012	belongs to the aldehyde dehydrogenase family
A1D33_RS14925	COG2199	diguanylate cyclase activity
A1D33_RS14925	COG2203	Gaf domain
A1D33_RS14930	COG1956	GAF domain-containing protein
A1D33_RS14935	COG1309	transcriptional regulator
A1D33_RS14940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A1D33_RS14950	COG1114	Component of the transport system for branched-chain amino acids
A1D33_RS14955	COG1104	cysteine desulfurase activity
A1D33_RS14970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A1D33_RS14975	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A1D33_RS14980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A1D33_RS14985	COG0616	signal peptide processing
A1D33_RS14990	COG1714	RDD family
A1D33_RS15000	COG3874	Sporulation protein YtfJ
A1D33_RS15005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A1D33_RS15010	COG0827	DNA restriction-modification system
A1D33_RS15020	COG0521	Mo-molybdopterin cofactor biosynthetic process
A1D33_RS15035	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS15045	COG4109	DRTGG domain
A1D33_RS15055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A1D33_RS15075	COG0587	DNA-directed DNA polymerase activity
A1D33_RS15080	COG0281	malic enzyme
A1D33_RS15105	COG0469	pyruvate kinase activity
A1D33_RS15110	COG3030	protein affecting phage T7 exclusion by the F plasmid
A1D33_RS15115	COG0628	permease
A1D33_RS15130	COG0372	Belongs to the citrate synthase family
A1D33_RS15135	COG0538	isocitrate dehydrogenase activity
A1D33_RS15145	COG0745	RESPONSE REGULATOR receiver
A1D33_RS15150	COG5002	protein histidine kinase activity
A1D33_RS15155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A1D33_RS15155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A1D33_RS15160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A1D33_RS15165	COG1971	Probably functions as a manganese efflux pump
A1D33_RS15170	COG0237	dephospho-CoA kinase activity
A1D33_RS15175	COG0656	L-ascorbic acid biosynthetic process
A1D33_RS15180	COG2814	Major facilitator Superfamily
A1D33_RS15185	COG1733	regulation of RNA biosynthetic process
A1D33_RS15190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A1D33_RS15205	COG3611	Membrane attachment protein
A1D33_RS15210	COG1484	DNA-dependent DNA replication
A1D33_RS15215	COG0398	Pfam SNARE associated Golgi protein
A1D33_RS15230	COG1011	Hydrolase
A1D33_RS15235	COG3275	phosphorelay sensor kinase activity
A1D33_RS15240	COG3279	Response regulator of the LytR AlgR family
A1D33_RS15245	COG1380	Effector of murein hydrolase LrgA
A1D33_RS15250	COG1346	cytolysis
A1D33_RS15255	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A1D33_RS15265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A1D33_RS15270	COG3326	Membrane
A1D33_RS15280	COG1363	Peptidase, m42
A1D33_RS15285	COG3507	Belongs to the glycosyl hydrolase 43 family
A1D33_RS15290	COG2160	L-arabinose isomerase activity
A1D33_RS15295	COG1069	ribulokinase activity
A1D33_RS15300	COG0235	Class ii aldolase
A1D33_RS15305	COG0647	UMP catabolic process
A1D33_RS15315	COG1653	transport
A1D33_RS15320	COG1175	transmembrane transport
A1D33_RS15325	COG0395	ABC-type sugar transport system, permease component
A1D33_RS15330	COG3534	alpha-L-arabinofuranosidase
A1D33_RS15335	COG1966	Carbon starvation protein
A1D33_RS15340	COG0247	lactate metabolic process
A1D33_RS15345	COG0277	FAD linked oxidase domain protein
A1D33_RS15350	COG3835	regulator
A1D33_RS15360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1D33_RS15365	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A1D33_RS15370	COG0072	phenylalanine-tRNA ligase activity
A1D33_RS15370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A1D33_RS15385	COG1286	toxin biosynthetic process
A1D33_RS15390	COG1796	DNA polymerase
A1D33_RS15390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A1D33_RS15400	COG3766	membrane
A1D33_RS15410	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS15415	COG1309	transcriptional regulator
A1D33_RS15420	COG1024	Enoyl-CoA hydratase
A1D33_RS15425	COG2086	electron transfer activity
A1D33_RS15430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A1D33_RS15435	COG3534	alpha-L-arabinofuranosidase
A1D33_RS15440	COG3118	belongs to the thioredoxin family
A1D33_RS15450	COG0527	aspartate kinase activity
A1D33_RS15455	COG1719	4-vinyl reductase, 4VR
A1D33_RS15460	COG2009	succinate dehydrogenase
A1D33_RS15465	COG1053	succinate dehydrogenase
A1D33_RS15470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A1D33_RS15475	COG0824	Thioesterase
A1D33_RS15480	COG2197	response regulator
A1D33_RS15485	COG1846	Transcriptional regulator
A1D33_RS15495	COG5401	PFAM Sporulation and spore germination
A1D33_RS15505	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A1D33_RS15510	COG0622	Phosphoesterase
A1D33_RS15530	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
A1D33_RS15545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A1D33_RS15560	COG0028	Belongs to the TPP enzyme family
A1D33_RS15565	COG0440	acetolactate synthase activity
A1D33_RS15580	COG0473	3-isopropylmalate dehydrogenase activity
A1D33_RS15595	COG1477	protein flavinylation
A1D33_RS15595	COG0457	Tetratricopeptide repeat
A1D33_RS15610	COG0470	DNA polymerase III
A1D33_RS15610	COG1067	ATP-dependent peptidase activity
A1D33_RS15615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A1D33_RS15635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1D33_RS15645	COG1587	Uroporphyrinogen-III synthase
A1D33_RS15650	COG0113	porphobilinogen synthase activity
A1D33_RS15660	COG1388	LysM domain
A1D33_RS15665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A1D33_RS15675	COG0525	valine-tRNA ligase activity
A1D33_RS15680	COG0285	dihydrofolate synthase activity
A1D33_RS15685	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A1D33_RS15705	COG1077	Cell shape determining protein MreB Mrl
A1D33_RS15715	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A1D33_RS15725	COG2894	cell division
A1D33_RS15730	COG0739	heme binding
A1D33_RS15735	COG1994	Peptidase M50
A1D33_RS15745	COG2868	ribosomal protein
A1D33_RS15750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A1D33_RS15755	COG3290	protein histidine kinase activity
A1D33_RS15770	COG0077	Prephenate dehydratase
A1D33_RS15775	COG1827	regulation of RNA biosynthetic process
A1D33_RS15780	COG1104	cysteine desulfurase activity
A1D33_RS15785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A1D33_RS15790	COG0157	Belongs to the NadC ModD family
A1D33_RS15800	COG1388	LysM domain
A1D33_RS15845	COG1862	Preprotein translocase
A1D33_RS15855	COG2323	membrane
A1D33_RS15860	COG2244	polysaccharide biosynthetic process
A1D33_RS15870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A1D33_RS15870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A1D33_RS15875	COG0490	domain, Protein
A1D33_RS15880	COG5416	Lipopolysaccharide assembly protein A domain
A1D33_RS15885	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A1D33_RS15885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A1D33_RS15895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A1D33_RS15905	COG4991	sh3 domain protein
A1D33_RS15905	COG3103	Sh3 type 3 domain protein
A1D33_RS15905	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS15925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A1D33_RS15930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A1D33_RS15935	COG1959	2 iron, 2 sulfur cluster binding
A1D33_RS15940	COG1104	cysteine desulfurase activity
A1D33_RS15950	COG0457	Tetratricopeptide repeat
A1D33_RS15955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A1D33_RS15960	COG3881	PFAM PRC-barrel domain
A1D33_RS15970	COG0765	amino acid transport
A1D33_RS15975	COG0765	amino acid transport
A1D33_RS15980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D33_RS15985	COG1126	abc transporter atp-binding protein
A1D33_RS15990	COG0628	permease
A1D33_RS16000	COG4472	Bacterial protein of unknown function (DUF965)
A1D33_RS16015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A1D33_RS16020	COG4122	O-methyltransferase activity
A1D33_RS16025	COG0826	peptidase U32
A1D33_RS16030	COG0826	peptidase U32
A1D33_RS16045	COG0768	penicillin binding
A1D33_RS16070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A1D33_RS16075	COG0626	cystathionine gamma-synthase activity
A1D33_RS16085	COG2427	Protein of unknown function (DUF1641)
A1D33_RS16090	COG3383	formate dehydrogenase (NAD+) activity
A1D33_RS16095	COG5609	conserved protein (DUF2294)
A1D33_RS16100	COG2116	formate transmembrane transporter activity
A1D33_RS16115	COG2226	methyltransferase
A1D33_RS16120	COG1309	transcriptional regulator
A1D33_RS16125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A1D33_RS16125	COG2124	cytochrome p450
A1D33_RS16130	COG2814	Major facilitator Superfamily
A1D33_RS16135	COG0583	DNA-binding transcription factor activity
A1D33_RS16140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A1D33_RS16150	COG3711	transcriptional antiterminator
A1D33_RS16150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D33_RS16155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1D33_RS16155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D33_RS16155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1D33_RS16160	COG1482	cell wall glycoprotein biosynthetic process
A1D33_RS16170	COG0561	phosphatase activity
A1D33_RS16175	COG0561	phosphatase activity
A1D33_RS16185	COG2318	DinB family
A1D33_RS16190	COG0456	acetyltransferase
A1D33_RS16195	COG2814	Major facilitator Superfamily
A1D33_RS16205	COG0563	adenylate kinase activity
A1D33_RS16210	COG0454	-acetyltransferase
A1D33_RS16215	COG2311	Membrane
A1D33_RS16220	COG0745	RESPONSE REGULATOR receiver
A1D33_RS16225	COG0642	Histidine kinase
A1D33_RS16225	COG5002	protein histidine kinase activity
A1D33_RS16245	COG3723	Recombinational DNA repair protein, rece pathway
A1D33_RS16255	COG0656	L-ascorbic acid biosynthetic process
A1D33_RS16265	COG1794	racemase activity, acting on amino acids and derivatives
A1D33_RS16270	COG3628	GPW Gp25 family protein
A1D33_RS16290	COG0398	Pfam SNARE associated Golgi protein
A1D33_RS16300	COG2755	lipolytic protein G-D-S-L family
A1D33_RS16310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A1D33_RS16315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A1D33_RS16320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A1D33_RS16325	COG1534	Rna-binding protein
A1D33_RS16335	COG1713	HD superfamily hydrolase involved in NAD metabolism
A1D33_RS16340	COG0799	negative regulation of ribosome biogenesis
A1D33_RS16345	COG2226	methyltransferase
A1D33_RS16350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A1D33_RS16355	COG1596	polysaccharide export
A1D33_RS16355	COG1555	photosystem II stabilization
A1D33_RS16360	COG2131	deaminase
A1D33_RS16365	COG0658	competence protein
A1D33_RS16365	COG2333	competence protein COMEC
A1D33_RS16370	COG1466	dna polymerase III delta subunit
A1D33_RS16385	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS16400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A1D33_RS16430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A1D33_RS16435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A1D33_RS16440	COG1283	sodium-dependent phosphate transmembrane transporter activity
A1D33_RS16450	COG1610	YqeY-like protein
A1D33_RS16455	COG1030	water channel activity
A1D33_RS16460	COG4864	UPF0365 protein
A1D33_RS16475	COG0561	phosphatase activity
A1D33_RS16480	COG1702	phosphate starvation-inducible protein PhoH
A1D33_RS16485	COG1480	7TM receptor with intracellular HD hydrolase
A1D33_RS16495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A1D33_RS16500	COG0295	cytidine deaminase activity
A1D33_RS16505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A1D33_RS16520	COG0751	glycine-tRNA ligase activity
A1D33_RS16525	COG0517	IMP dehydrogenase activity
A1D33_RS16540	COG0358	DNA primase activity
A1D33_RS16545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A1D33_RS16550	COG2010	Cytochrome c
A1D33_RS16555	COG2384	SAM-dependent methyltransferase
A1D33_RS16560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A1D33_RS16575	COG0513	Belongs to the DEAD box helicase family
A1D33_RS16590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A1D33_RS16595	COG0735	belongs to the Fur family
A1D33_RS16600	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
A1D33_RS16605	COG4709	membrane
A1D33_RS16615	COG1388	LysM domain
A1D33_RS16620	COG5521	maltodextrose utilization protein MalA
A1D33_RS16625	COG2839	Protein conserved in bacteria
A1D33_RS16630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A1D33_RS16635	COG0477	Major facilitator Superfamily
A1D33_RS16640	COG0768	penicillin binding
A1D33_RS16645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A1D33_RS16650	COG0573	inorganic phosphate transmembrane transporter activity
A1D33_RS16655	COG0581	inorganic phosphate transmembrane transporter activity
A1D33_RS16660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A1D33_RS16665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A1D33_RS16670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A1D33_RS16680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A1D33_RS16685	COG1757	Na H antiporter
A1D33_RS16690	COG4483	Protein conserved in bacteria
A1D33_RS16695	COG1940	carbohydrate kinase activity
A1D33_RS16700	COG2866	Carboxypeptidase
A1D33_RS16710	COG0011	TIGRFAM Protein of
A1D33_RS16715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1D33_RS16725	COG1393	Belongs to the ArsC family
A1D33_RS16735	COG1366	Belongs to the anti-sigma-factor antagonist family
A1D33_RS16740	COG1253	flavin adenine dinucleotide binding
A1D33_RS16745	COG0598	Magnesium transport protein CorA
A1D33_RS16750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A1D33_RS16755	COG1459	type II secretion system
A1D33_RS16760	COG4537	Required for transformation and DNA binding
A1D33_RS16765	COG4970	Tfp pilus assembly protein FimT
A1D33_RS16775	COG4940	Competence protein ComGF
A1D33_RS16800	COG0681	Belongs to the peptidase S26 family
A1D33_RS16810	COG1396	sequence-specific DNA binding
A1D33_RS16825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A1D33_RS16845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A1D33_RS16860	COG1752	Esterase of the alpha-beta hydrolase superfamily
A1D33_RS16870	COG3872	metal-dependent enzyme
A1D33_RS16880	COG0006	proline dipeptidase activity
A1D33_RS16895	COG3854	ATPases associated with a variety of cellular activities
A1D33_RS16935	COG0511	ligase activity, forming carbon-carbon bonds
A1D33_RS16940	COG0439	Biotin carboxylase
A1D33_RS16945	COG1302	Protein conserved in bacteria
A1D33_RS16960	COG1570	exodeoxyribonuclease VII activity
A1D33_RS16970	COG0142	geranyltranstransferase activity
A1D33_RS16980	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A1D33_RS16990	COG0497	DNA recombination
A1D33_RS16995	COG0750	zinc metalloprotease
A1D33_RS17000	COG0745	RESPONSE REGULATOR receiver
A1D33_RS17005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A1D33_RS17020	COG1902	pentaerythritol trinitrate reductase activity
A1D33_RS17045	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS17050	COG0584	glycerophosphoryl diester phosphodiesterase
A1D33_RS17055	COG0183	Belongs to the thiolase family
A1D33_RS17060	COG1250	3-hydroxyacyl-CoA dehydrogenase
A1D33_RS17065	COG1960	acyl-CoA dehydrogenase activity
A1D33_RS17070	COG0372	Belongs to the citrate synthase family
A1D33_RS17075	COG2079	MmgE PrpD family protein
A1D33_RS17080	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A1D33_RS17090	COG3829	transcription factor binding
A1D33_RS17090	COG3290	protein histidine kinase activity
A1D33_RS17095	COG0280	phosphate acetyltransferase
A1D33_RS17100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A1D33_RS17105	COG3426	butyrate kinase activity
A1D33_RS17110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1D33_RS17115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A1D33_RS17120	COG0022	dehydrogenase e1 component
A1D33_RS17125	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1D33_RS17130	COG1597	lipid kinase activity
A1D33_RS17140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D33_RS17145	COG0765	amino acid transport
A1D33_RS17150	COG1126	abc transporter atp-binding protein
A1D33_RS17155	COG4129	membrane
A1D33_RS17160	COG1376	ErfK ybiS ycfS ynhG family protein
A1D33_RS17165	COG0346	lactoylglutathione lyase activity
A1D33_RS17170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A1D33_RS17175	COG2195	Cleaves the N-terminal amino acid of tripeptides
A1D33_RS17180	COG0706	membrane insertase activity
A1D33_RS17195	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A1D33_RS17200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A1D33_RS17215	COG0596	Alpha beta hydrolase
A1D33_RS17235	COG0250	Participates in transcription elongation, termination and antitermination
A1D33_RS17240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A1D33_RS17240	COG2070	2-Nitropropane dioxygenase
A1D33_RS17255	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS17260	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS17265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D33_RS17265	COG3321	synthase
A1D33_RS17265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS17265	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS17265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS17270	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS17270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS17270	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS17270	COG3321	synthase
A1D33_RS17270	COG0300	oxidoreductase activity
A1D33_RS17275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS17275	COG3321	synthase
A1D33_RS17275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D33_RS17275	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS17275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS17280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS17280	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS17280	COG3321	synthase
A1D33_RS17280	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS17280	COG0300	oxidoreductase activity
A1D33_RS17285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS17285	COG0318	PFAM AMP-dependent synthetase and ligase
A1D33_RS17285	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS17285	COG3321	synthase
A1D33_RS17285	COG0300	oxidoreductase activity
A1D33_RS17290	COG3321	synthase
A1D33_RS17290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS17290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D33_RS17290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS17295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D33_RS17295	COG3321	synthase
A1D33_RS17295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D33_RS17295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D33_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
A1D33_RS17300	COG2124	cytochrome p450
A1D33_RS17305	COG3425	synthase
A1D33_RS17310	COG1024	Enoyl-CoA hydratase
A1D33_RS17315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A1D33_RS17320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1D33_RS17325	COG0300	oxidoreductase activity
A1D33_RS17330	COG3048	D-serine ammonia-lyase activity
A1D33_RS17340	COG0346	lactoylglutathione lyase activity
A1D33_RS17345	COG0628	permease
A1D33_RS17360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A1D33_RS17365	COG0456	acetyltransferase
A1D33_RS17370	COG2329	Antibiotic biosynthesis monooxygenase
A1D33_RS17375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A1D33_RS17375	COG0456	acetyltransferase
A1D33_RS17380	COG4918	Iron-sulphur cluster biosynthesis
A1D33_RS17390	COG1073	alpha beta
A1D33_RS17400	COG0667	Aldo Keto reductase
A1D33_RS17410	COG0494	nUDIX hydrolase
A1D33_RS17415	COG1379	DNA repair
A1D33_RS17420	COG1396	sequence-specific DNA binding
A1D33_RS17425	COG0252	asparaginase activity
A1D33_RS17430	COG1027	Aspartate ammonia-lyase
A1D33_RS17435	COG1757	Na H antiporter
A1D33_RS17440	COG0281	malic enzyme
A1D33_RS17455	COG1300	Membrane
A1D33_RS17460	COG0735	belongs to the Fur family
A1D33_RS17470	COG4974	Belongs to the 'phage' integrase family
A1D33_RS17475	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A1D33_RS17480	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A1D33_RS17485	COG1686	Belongs to the peptidase S11 family
A1D33_RS17490	COG1366	Belongs to the anti-sigma-factor antagonist family
A1D33_RS17500	COG1191	sigma factor activity
A1D33_RS17520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A1D33_RS17535	COG0697	spore germination
A1D33_RS17540	COG0019	diaminopimelate decarboxylase activity
A1D33_RS17545	COG4086	secreted protein
A1D33_RS17550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A1D33_RS17560	COG0681	Belongs to the peptidase S26 family
A1D33_RS17570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A1D33_RS17570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A1D33_RS17575	COG0307	riboflavin synthase, alpha
A1D33_RS17590	COG0456	acetyltransferase
A1D33_RS17595	COG1547	Domain of unknown function (DUF309)
A1D33_RS17615	COG1686	Belongs to the peptidase S11 family
A1D33_RS17620	COG2715	membrane protein required for spore maturation
A1D33_RS17625	COG0700	Nucleoside recognition
A1D33_RS17630	COG1187	pseudouridine synthase activity
A1D33_RS17635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS17640	COG1333	cytochrome c biogenesis protein
A1D33_RS17645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1D33_RS17650	COG0745	RESPONSE REGULATOR receiver
A1D33_RS17655	COG5002	protein histidine kinase activity
A1D33_RS17660	COG1595	DNA-templated transcription, initiation
A1D33_RS17670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A1D33_RS17675	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A1D33_RS17680	COG1141	Ferredoxin
A1D33_RS17685	COG4955	Helix-turn-helix domain
A1D33_RS17690	COG0514	ATP-dependent DNA helicase (RecQ)
A1D33_RS17695	COG1266	CAAX protease self-immunity
A1D33_RS17700	COG1388	LysM domain
A1D33_RS17710	COG1408	metallophosphoesterase
A1D33_RS17715	COG4862	establishment of competence for transformation
A1D33_RS17720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A1D33_RS17725	COG0492	ferredoxin-NADP+ reductase activity
A1D33_RS17730	COG2339	peptidase activity
A1D33_RS17735	COG3773	Cell wall hydrolase
A1D33_RS17735	COG3409	Peptidoglycan-binding domain 1 protein
A1D33_RS17740	COG2959	enzyme of heme biosynthesis
A1D33_RS17745	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
A1D33_RS17755	COG0539	negative regulation of cytoplasmic translation
A1D33_RS17790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A1D33_RS17795	COG0776	regulation of translation
A1D33_RS17810	COG0142	geranyltranstransferase activity
A1D33_RS17820	COG0142	geranyltranstransferase activity
A1D33_RS17825	COG0105	UTP biosynthetic process
A1D33_RS17830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A1D33_RS17845	COG4401	Chorismate mutase type I
A1D33_RS17850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A1D33_RS17885	COG0287	Prephenate dehydrogenase
A1D33_RS17895	COG0457	Tetratricopeptide repeat
A1D33_RS17910	COG0723	plastoquinol--plastocyanin reductase activity
A1D33_RS17915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A1D33_RS17920	COG2010	Cytochrome c
A1D33_RS17920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A1D33_RS17925	COG4347	Protein of unknown function (DUF1405)
A1D33_RS17935	COG2140	Oxalate decarboxylase
A1D33_RS17940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A1D33_RS17945	COG1694	Mazg nucleotide pyrophosphohydrolase
A1D33_RS17960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A1D33_RS17965	COG0438	transferase activity, transferring glycosyl groups
A1D33_RS17995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A1D33_RS17995	COG1199	ATP-dependent helicase activity
A1D33_RS18000	COG5353	protein conserved in bacteria
A1D33_RS18005	COG0436	Aminotransferase
A1D33_RS18015	COG3935	DnaD domain protein
A1D33_RS18020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A1D33_RS18030	COG4499	WXG100 protein secretion system (Wss), protein YukC
A1D33_RS18030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A1D33_RS18070	COG0071	Belongs to the small heat shock protein (HSP20) family
A1D33_RS18075	COG2190	(PTS) system
A1D33_RS18080	COG1111	helicase
A1D33_RS18080	COG1205	dead DEAH box helicase
A1D33_RS18085	COG3359	exonuclease
A1D33_RS18105	COG0116	Belongs to the methyltransferase superfamily
A1D33_RS18115	COG1199	ATP-dependent helicase activity
A1D33_RS18120	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A1D33_RS18130	COG2233	PERMEase
A1D33_RS18140	COG1525	nuclease
A1D33_RS18145	COG5444	nuclease activity
A1D33_RS18180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A1D33_RS18185	COG0457	Tetratricopeptide repeat
A1D33_RS18210	COG5632	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS18210	COG3409	Peptidoglycan-binding domain 1 protein
A1D33_RS18215	COG5434	Belongs to the glycosyl hydrolase 28 family
A1D33_RS18225	COG2433	Pfam Transposase IS66
A1D33_RS18235	COG0741	lytic transglycosylase activity
A1D33_RS18235	COG0739	heme binding
A1D33_RS18235	COG1196	nuclear chromosome segregation
A1D33_RS18385	COG0776	regulation of translation
A1D33_RS18465	COG3655	Transcriptional regulator
A1D33_RS18470	COG3655	Transcriptional regulator
A1D33_RS18555	COG3655	Transcriptional regulator
A1D33_RS18630	COG0756	dUTP diphosphatase activity
A1D33_RS18635	COG1793	dna ligase
A1D33_RS18640	COG2135	peptidase activity
A1D33_RS18660	COG4195	phage-related replication protein
A1D33_RS18665	COG5434	Belongs to the glycosyl hydrolase 28 family
A1D33_RS18665	COG3420	alginic acid biosynthetic process
A1D33_RS18695	COG2887	Belongs to the helicase family. UvrD subfamily
A1D33_RS18705	COG0305	Participates in initiation and elongation during chromosome replication
A1D33_RS18710	COG0358	DNA primase activity
A1D33_RS18715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A1D33_RS18720	COG0587	DNA-directed DNA polymerase activity
A1D33_RS18725	COG3584	3D domain protein
A1D33_RS18735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A1D33_RS18820	COG1780	Probably involved in ribonucleotide reductase function
A1D33_RS18825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A1D33_RS18835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A1D33_RS18840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D33_RS18855	COG4112	unkown
A1D33_RS18875	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A1D33_RS18880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A1D33_RS18980	COG3331	DNA recombination
A1D33_RS18985	COG2233	PERMEase
A1D33_RS18995	COG1335	isochorismatase
A1D33_RS19020	COG3424	synthase
A1D33_RS19025	COG1755	Isoprenylcysteine carboxyl methyltransferase
A1D33_RS19030	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A1D33_RS19040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A1D33_RS19050	COG0328	RNA-DNA hybrid ribonuclease activity
A1D33_RS19055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A1D33_RS19060	COG0328	RNA-DNA hybrid ribonuclease activity
A1D33_RS19080	COG1278	Cold shock
A1D33_RS19085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A1D33_RS19095	COG0386	Belongs to the glutathione peroxidase family
A1D33_RS19105	COG1413	lyase activity
A1D33_RS19120	COG2136	Putative SAM-dependent methyltransferase
A1D33_RS19120	COG2521	methyltransferase
A1D33_RS19135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A1D33_RS19140	COG0204	Acyl-transferase
A1D33_RS19145	COG1272	protein, Hemolysin III
A1D33_RS19150	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A1D33_RS19155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A1D33_RS19165	COG1999	signal sequence binding
A1D33_RS19170	COG2755	lipolytic protein G-D-S-L family
A1D33_RS19175	COG4698	Protein conserved in bacteria
A1D33_RS19180	COG1846	Transcriptional regulator
A1D33_RS19200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A1D33_RS19205	COG1525	nuclease
A1D33_RS19210	COG4282	regulation of fungal-type cell wall biogenesis
A1D33_RS19215	COG5444	nuclease activity
A1D33_RS19235	COG0457	Tetratricopeptide repeat
A1D33_RS19240	COG1388	LysM domain
A1D33_RS19280	COG1086	Polysaccharide biosynthesis protein
A1D33_RS19290	COG4641	Protein conserved in bacteria
A1D33_RS19305	COG0463	Glycosyl transferase, family 2
A1D33_RS19310	COG0456	acetyltransferase
A1D33_RS19320	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A1D33_RS19325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A1D33_RS19330	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A1D33_RS19335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A1D33_RS19340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A1D33_RS19345	COG0456	acetyltransferase
A1D33_RS19350	COG1509	lysine 2,3-aminomutase activity
A1D33_RS19375	COG0671	phosphoesterase, PA-phosphatase related
A1D33_RS19390	COG1876	peptidase activity
A1D33_RS19400	COG2226	methyltransferase
A1D33_RS19405	COG3409	Peptidoglycan-binding domain 1 protein
A1D33_RS19405	COG0793	Belongs to the peptidase S41A family
A1D33_RS19410	COG2188	Transcriptional regulator
A1D33_RS19415	COG2723	6-phospho-beta-galactosidase activity
A1D33_RS19425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A1D33_RS19435	COG0346	lactoylglutathione lyase activity
A1D33_RS19440	COG0400	carboxylic ester hydrolase activity
A1D33_RS19445	COG0778	Nitroreductase
A1D33_RS19450	COG1733	regulation of RNA biosynthetic process
A1D33_RS19460	COG1942	4-Oxalocrotonate Tautomerase
A1D33_RS19475	COG2962	Rard protein
A1D33_RS19485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A1D33_RS19490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A1D33_RS19495	COG1366	Belongs to the anti-sigma-factor antagonist family
A1D33_RS19500	COG0534	Mate efflux family protein
A1D33_RS19505	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A1D33_RS19510	COG1819	glycosyl
A1D33_RS19515	COG1388	LysM domain
A1D33_RS19515	COG0791	NLP P60 protein
A1D33_RS19520	COG2032	superoxide dismutase activity
A1D33_RS19525	COG0714	Associated with various cellular activities
A1D33_RS19530	COG4548	von Willebrand factor, type A
A1D33_RS19540	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1D33_RS19545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1D33_RS19550	COG0385	Bile acid
A1D33_RS19555	COG0733	neurotransmitter:sodium symporter activity
A1D33_RS19560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A1D33_RS19565	COG1657	PFAM Prenyltransferase squalene oxidase
A1D33_RS19570	COG1012	belongs to the aldehyde dehydrogenase family
A1D33_RS19595	COG0071	Belongs to the small heat shock protein (HSP20) family
A1D33_RS19610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A1D33_RS19615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A1D33_RS19625	COG0514	ATP-dependent DNA helicase (RecQ)
A1D33_RS19630	COG3584	3D domain protein
A1D33_RS19630	COG1388	LysM domain
A1D33_RS19640	COG1619	proteins homologs of microcin C7 resistance protein MccF
A1D33_RS19655	COG2322	membrane
A1D33_RS19660	COG0741	lytic transglycosylase activity
A1D33_RS19665	COG0640	Transcriptional regulator
A1D33_RS19675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1D33_RS19680	COG1309	transcriptional regulator
A1D33_RS19685	COG2207	Transcriptional regulator
A1D33_RS19685	COG0662	Cupin 2, conserved barrel domain protein
A1D33_RS19690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A1D33_RS19695	COG5444	nuclease activity
A1D33_RS19725	COG0243	molybdopterin cofactor binding
A1D33_RS19730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A1D33_RS19735	COG1070	Carbohydrate kinase
A1D33_RS19740	COG2814	Major facilitator Superfamily
A1D33_RS19750	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A1D33_RS19755	COG0300	oxidoreductase activity
A1D33_RS19770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A1D33_RS19775	COG0583	DNA-binding transcription factor activity
A1D33_RS19780	COG0069	glutamate synthase activity
A1D33_RS19780	COG0067	glutamate synthase
A1D33_RS19780	COG0070	glutamate synthase
A1D33_RS19785	COG0493	'glutamate synthase
A1D33_RS19790	COG0604	alcohol dehydrogenase
A1D33_RS19800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A1D33_RS19805	COG0640	Transcriptional regulator
A1D33_RS19810	COG2814	Major facilitator Superfamily
A1D33_RS19815	COG0405	Gamma-glutamyltransferase
A1D33_RS19820	COG0166	Belongs to the GPI family
A1D33_RS19825	COG0582	viral genome integration into host DNA
A1D33_RS19915	COG1595	DNA-templated transcription, initiation
A1D33_RS19920	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A1D33_RS19925	COG0582	viral genome integration into host DNA
A1D33_RS19965	COG4626	Terminase
A1D33_RS19965	COG1802	Transcriptional regulator
A1D33_RS20045	COG1388	LysM domain
A1D33_RS20045	COG1705	Flagellar rod assembly protein muramidase FlgJ
A1D33_RS20050	COG5434	Belongs to the glycosyl hydrolase 28 family
A1D33_RS20070	COG4824	toxin secretion phage lysis holin
A1D33_RS20075	COG5632	N-Acetylmuramoyl-L-alanine amidase
A1D33_RS20075	COG3409	Peptidoglycan-binding domain 1 protein
A1D33_RS20090	COG5444	nuclease activity
A1D33_RS20100	COG0534	Mate efflux family protein
A1D33_RS20105	COG2017	converts alpha-aldose to the beta-anomer
A1D33_RS20110	COG2027	D-alanyl-D-alanine carboxypeptidase
A1D33_RS20135	COG5583	Uncharacterized small protein (DUF2292)
A1D33_RS20145	COG3093	addiction module antidote protein HigA