locus-tag	class	description
C3Z10_RS00010	COG0592	DNA-directed DNA polymerase activity
C3Z10_RS00015	COG2501	S4 domain
C3Z10_RS00030	COG0187	DNA topoisomerase II activity
C3Z10_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C3Z10_RS00070	COG0517	IMP dehydrogenase activity
C3Z10_RS00070	COG0516	GMP reductase activity
C3Z10_RS00075	COG1686	Belongs to the peptidase S11 family
C3Z10_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
C3Z10_RS00105	COG1428	Deoxynucleoside kinase
C3Z10_RS00110	COG1428	Deoxynucleoside kinase
C3Z10_RS00115	COG3858	chitin binding
C3Z10_RS00115	COG1388	LysM domain
C3Z10_RS00120	COG1335	isochorismatase
C3Z10_RS00125	COG0590	tRNA wobble adenosine to inosine editing
C3Z10_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C3Z10_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C3Z10_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C3Z10_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C3Z10_RS00195	COG3853	Toxic anion resistance protein (TelA)
C3Z10_RS00200	COG1982	Orn Lys Arg decarboxylase major
C3Z10_RS00210	COG3870	Protein conserved in bacteria
C3Z10_RS00215	COG1728	Protein conserved in bacteria
C3Z10_RS00220	COG0470	DNA polymerase III
C3Z10_RS00225	COG1774	PSP1 C-terminal conserved region
C3Z10_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C3Z10_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C3Z10_RS00250	COG2002	toxin-antitoxin pair type II binding
C3Z10_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3Z10_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3Z10_RS00260	COG0084	hydrolase, TatD family'
C3Z10_RS00265	COG3583	domain protein
C3Z10_RS00265	COG3584	3D domain protein
C3Z10_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C3Z10_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C3Z10_RS00285	COG4466	Protein conserved in bacteria
C3Z10_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C3Z10_RS00305	COG0251	oxidation-reduction process
C3Z10_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C3Z10_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C3Z10_RS00345	COG2002	toxin-antitoxin pair type II binding
C3Z10_RS00350	COG2244	polysaccharide biosynthetic process
C3Z10_RS00355	COG3956	TIGRFAM MazG family protein
C3Z10_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C3Z10_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C3Z10_RS00380	COG1098	S1 RNA binding domain
C3Z10_RS00395	COG2208	phosphoserine phosphatase activity
C3Z10_RS00400	COG2304	oxidoreductase activity
C3Z10_RS00405	COG0515	serine threonine protein kinase
C3Z10_RS00410	COG0037	tRNA processing
C3Z10_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C3Z10_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3Z10_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3Z10_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3Z10_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C3Z10_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
C3Z10_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3Z10_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C3Z10_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C3Z10_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C3Z10_RS00475	COG1396	sequence-specific DNA binding
C3Z10_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3Z10_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C3Z10_RS00570	COG4463	regulation of RNA biosynthetic process
C3Z10_RS00575	COG3880	PFAM UvrB UvrC protein
C3Z10_RS00585	COG0542	response to heat
C3Z10_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C3Z10_RS00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C3Z10_RS00600	COG4956	integral membrane protein (PIN domain superfamily)
C3Z10_RS00620	COG1045	serine acetyltransferase
C3Z10_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C3Z10_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3Z10_RS00640	COG3688	RNA-binding protein containing a PIN domain
C3Z10_RS00645	COG1595	DNA-templated transcription, initiation
C3Z10_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C3Z10_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
C3Z10_RS00685	COG2813	Specifically methylates the guanine in position
C3Z10_RS00700	COG1358	cellular component organization or biogenesis
C3Z10_RS00725	COG0596	Alpha beta hydrolase
C3Z10_RS00835	COG0201	protein transport
C3Z10_RS00845	COG0024	Methionine aminopeptidase
C3Z10_RS00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C3Z10_RS00885	COG1122	ATPase activity
C3Z10_RS00890	COG1122	ATPase activity
C3Z10_RS00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C3Z10_RS00915	COG2226	methyltransferase
C3Z10_RS00920	COG2318	DinB family
C3Z10_RS00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS00935	COG0489	protein tyrosine kinase activity
C3Z10_RS00945	COG2194	sulfuric ester hydrolase activity
C3Z10_RS00950	COG0726	polysaccharide deacetylase
C3Z10_RS01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C3Z10_RS01030	COG0659	secondary active sulfate transmembrane transporter activity
C3Z10_RS01035	COG0385	Bile acid
C3Z10_RS01040	COG2819	hydrolase of the alpha beta superfamily
C3Z10_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3Z10_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3Z10_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3Z10_RS01060	COG2207	Transcriptional regulator
C3Z10_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3Z10_RS01065	COG3876	Protein conserved in bacteria
C3Z10_RS01070	COG1472	Belongs to the glycosyl hydrolase 3 family
C3Z10_RS01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3Z10_RS01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3Z10_RS01080	COG1263	PTS System
C3Z10_RS01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3Z10_RS01095	COG1683	Conserved Protein
C3Z10_RS01125	COG1595	DNA-templated transcription, initiation
C3Z10_RS01130	COG5662	AntiSigma factor
C3Z10_RS01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C3Z10_RS01140	COG4856	YbbR-like protein
C3Z10_RS01180	COG1346	cytolysis
C3Z10_RS01185	COG1380	Effector of murein hydrolase LrgA
C3Z10_RS01190	COG1846	Transcriptional regulator
C3Z10_RS01195	COG1113	amino acid transport
C3Z10_RS01200	COG1011	Hydrolase
C3Z10_RS01205	COG4585	Histidine kinase
C3Z10_RS01210	COG2197	response regulator
C3Z10_RS01215	COG1131	(ABC) transporter
C3Z10_RS01235	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C3Z10_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS01255	COG4221	oxidoreductase activity
C3Z10_RS01255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS01255	COG3321	synthase
C3Z10_RS01260	COG0300	oxidoreductase activity
C3Z10_RS01260	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS01260	COG3321	synthase
C3Z10_RS01260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS01260	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS01300	COG0531	amino acid
C3Z10_RS01305	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C3Z10_RS01320	COG0584	glycerophosphoryl diester phosphodiesterase
C3Z10_RS01325	COG2271	Major facilitator Superfamily
C3Z10_RS01340	COG2368	4-hydroxyphenylacetate
C3Z10_RS01350	COG3409	Peptidoglycan-binding domain 1 protein
C3Z10_RS01365	COG0371	Dehydrogenase
C3Z10_RS01380	COG1183	phosphatidylcholine synthase activity
C3Z10_RS01385	COG0586	Pfam SNARE associated Golgi protein
C3Z10_RS01390	COG0688	phosphatidylethanolamine metabolic process
C3Z10_RS01405	COG1301	dicarboxylic acid transport
C3Z10_RS01410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3Z10_RS01415	COG0833	amino acid
C3Z10_RS01420	COG2040	homocysteine
C3Z10_RS01425	COG1115	amino acid carrier protein
C3Z10_RS01430	COG2066	Belongs to the glutaminase family
C3Z10_RS01435	COG4191	Histidine kinase
C3Z10_RS01440	COG0784	Response regulator, receiver
C3Z10_RS01460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C3Z10_RS01465	COG0778	Nitroreductase
C3Z10_RS01470	COG0346	lactoylglutathione lyase activity
C3Z10_RS01475	COG2259	Doxx family
C3Z10_RS01480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS01495	COG3773	Cell wall hydrolase
C3Z10_RS01505	COG3540	Alkaline phosphatase
C3Z10_RS01510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C3Z10_RS01515	COG0805	protein transport
C3Z10_RS01525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C3Z10_RS01530	COG0477	Major facilitator Superfamily
C3Z10_RS01535	COG1309	transcriptional regulator
C3Z10_RS01540	COG0252	asparaginase activity
C3Z10_RS01545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C3Z10_RS01550	COG3012	SEC-C Motif Domain Protein
C3Z10_RS01550	COG1405	negative regulation of cell septum assembly
C3Z10_RS01555	COG0667	Aldo Keto reductase
C3Z10_RS01565	COG1595	DNA-templated transcription, initiation
C3Z10_RS01570	COG1595	DNA-templated transcription, initiation
C3Z10_RS01575	COG1876	peptidase activity
C3Z10_RS01580	COG0457	Tetratricopeptide repeat
C3Z10_RS01585	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS01590	COG0366	Alpha amylase catalytic
C3Z10_RS01595	COG0803	Belongs to the bacterial solute-binding protein 9 family
C3Z10_RS01600	COG1121	(ABC) transporter
C3Z10_RS01605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3Z10_RS01610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3Z10_RS01615	COG2310	stress, protein
C3Z10_RS01620	COG2310	stress, protein
C3Z10_RS01625	COG2310	stress, protein
C3Z10_RS01630	COG0861	Integral membrane protein TerC family
C3Z10_RS01640	COG3853	Toxic anion resistance protein (TelA)
C3Z10_RS01645	COG0477	Major facilitator Superfamily
C3Z10_RS01650	COG4175	Glycine betaine
C3Z10_RS01650	COG0517	IMP dehydrogenase activity
C3Z10_RS01655	COG4176	ABC-type proline glycine betaine transport system permease component
C3Z10_RS01660	COG2113	Glycine betaine
C3Z10_RS01665	COG1473	amidohydrolase
C3Z10_RS01670	COG1288	antiporter activity
C3Z10_RS01685	COG0457	Tetratricopeptide repeat
C3Z10_RS01705	COG0741	lytic transglycosylase activity
C3Z10_RS01705	COG0791	NLP P60 protein
C3Z10_RS01710	COG5644	endopeptidase inhibitor activity
C3Z10_RS01720	COG0433	COG0433 Predicted ATPase
C3Z10_RS01755	COG2946	Replication initiation factor
C3Z10_RS01760	COG1674	ftsk spoiiie
C3Z10_RS01780	COG1396	sequence-specific DNA binding
C3Z10_RS01785	COG2856	Zn peptidase
C3Z10_RS01790	COG0582	viral genome integration into host DNA
C3Z10_RS01795	COG0366	Alpha amylase catalytic
C3Z10_RS01805	COG2814	Major facilitator Superfamily
C3Z10_RS01810	COG1846	Transcriptional regulator
C3Z10_RS01815	COG1280	lysine exporter protein (LysE YggA)
C3Z10_RS01820	COG3403	YqcI/YcgG family
C3Z10_RS01825	COG1113	amino acid transport
C3Z10_RS01830	COG3665	Urea carboxylase-associated protein
C3Z10_RS01845	COG1082	Xylose isomerase domain protein TIM barrel
C3Z10_RS01850	COG2271	Major facilitator Superfamily
C3Z10_RS01855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C3Z10_RS01860	COG3458	cephalosporin-C deacetylase activity
C3Z10_RS01865	COG3541	Predicted nucleotidyltransferase
C3Z10_RS01870	COG0506	proline dehydrogenase activity
C3Z10_RS01875	COG1012	belongs to the aldehyde dehydrogenase family
C3Z10_RS01880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3Z10_RS01885	COG2508	Transcriptional regulator
C3Z10_RS01895	COG1587	Uroporphyrinogen-III synthase
C3Z10_RS01895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C3Z10_RS01900	COG2146	nitrite reductase [NAD(P)H] activity
C3Z10_RS01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3Z10_RS01910	COG0243	molybdopterin cofactor binding
C3Z10_RS01915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3Z10_RS01920	COG2223	nitrite transmembrane transporter activity
C3Z10_RS01925	COG0523	cobalamin synthesis protein
C3Z10_RS01930	COG1063	alcohol dehydrogenase
C3Z10_RS01935	COG1714	RDD family
C3Z10_RS01945	COG2723	6-phospho-beta-galactosidase activity
C3Z10_RS01955	COG3209	COG3209 Rhs family protein
C3Z10_RS01960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C3Z10_RS01965	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C3Z10_RS01970	COG1733	regulation of RNA biosynthetic process
C3Z10_RS01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS01990	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C3Z10_RS02005	COG0697	spore germination
C3Z10_RS02010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3Z10_RS02020	COG2364	Membrane
C3Z10_RS02025	COG1126	abc transporter atp-binding protein
C3Z10_RS02030	COG0765	amino acid transport
C3Z10_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3Z10_RS02040	COG0583	DNA-binding transcription factor activity
C3Z10_RS02045	COG0163	prenyltransferase activity
C3Z10_RS02050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C3Z10_RS02065	COG3104	oligopeptide transport
C3Z10_RS02070	COG5434	Belongs to the glycosyl hydrolase 28 family
C3Z10_RS02080	COG0697	spore germination
C3Z10_RS02090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C3Z10_RS02095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3Z10_RS02100	COG0456	acetyltransferase
C3Z10_RS02105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3Z10_RS02110	COG0765	amino acid transport
C3Z10_RS02115	COG1126	abc transporter atp-binding protein
C3Z10_RS02120	COG1473	amidohydrolase
C3Z10_RS02125	COG2079	MmgE PrpD family protein
C3Z10_RS02130	COG1136	(ABC) transporter
C3Z10_RS02135	COG0577	efflux transmembrane transporter activity
C3Z10_RS02140	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS02145	COG5002	protein histidine kinase activity
C3Z10_RS02145	COG3850	Histidine kinase
C3Z10_RS02150	COG0457	Tetratricopeptide repeat
C3Z10_RS02165	COG0527	aspartate kinase activity
C3Z10_RS02170	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3Z10_RS02175	COG4605	iron ion homeostasis
C3Z10_RS02180	COG4604	ABC transporter, ATP-binding protein
C3Z10_RS02185	COG4607	ABC-type enterochelin transport system periplasmic component
C3Z10_RS02190	COG2814	Major facilitator Superfamily
C3Z10_RS02195	COG1309	transcriptional regulator
C3Z10_RS02200	COG0778	Nitroreductase
C3Z10_RS02205	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C3Z10_RS02210	COG0640	Transcriptional regulator
C3Z10_RS02215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3Z10_RS02220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C3Z10_RS02225	COG1012	belongs to the aldehyde dehydrogenase family
C3Z10_RS02230	COG4975	Glucose uptake
C3Z10_RS02235	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS02240	COG4549	nuclear export factor GLE1
C3Z10_RS02245	COG2372	response to copper ion
C3Z10_RS02245	COG1276	copper resistance
C3Z10_RS02250	COG1349	DNA-binding transcription factor activity
C3Z10_RS02260	COG2213	PTS system mannitol-specific
C3Z10_RS02265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3Z10_RS02275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C3Z10_RS02285	COG0561	phosphatase activity
C3Z10_RS02295	COG1914	H( )-stimulated, divalent metal cation uptake system
C3Z10_RS02305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C3Z10_RS02310	COG1984	allophanate hydrolase subunit 2
C3Z10_RS02315	COG1414	Transcriptional regulator
C3Z10_RS02320	COG2755	lipolytic protein G-D-S-L family
C3Z10_RS02330	COG2329	Antibiotic biosynthesis monooxygenase
C3Z10_RS02335	COG0768	penicillin binding
C3Z10_RS02340	COG4989	oxidoreductase activity
C3Z10_RS02345	COG3711	transcriptional antiterminator
C3Z10_RS02350	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS02355	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS02360	COG1917	Cupin 2, conserved barrel domain protein
C3Z10_RS02365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3Z10_RS02370	COG3871	stress protein (general stress protein 26)
C3Z10_RS02380	COG2814	Major facilitator Superfamily
C3Z10_RS02385	COG1522	sequence-specific DNA binding
C3Z10_RS02390	COG0551	DNA topoisomerase type I activity
C3Z10_RS02390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C3Z10_RS02395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C3Z10_RS02400	COG3706	GGDEF domain
C3Z10_RS02405	COG5298	Protein conserved in bacteria
C3Z10_RS02410	COG1215	transferase activity, transferring glycosyl groups
C3Z10_RS02420	COG0531	amino acid
C3Z10_RS02425	COG0494	nUDIX hydrolase
C3Z10_RS02430	COG0028	Belongs to the TPP enzyme family
C3Z10_RS02460	COG0457	Tetratricopeptide repeat
C3Z10_RS02490	COG1914	H( )-stimulated, divalent metal cation uptake system
C3Z10_RS02505	COG4876	unkown
C3Z10_RS02515	COG2076	Multidrug Resistance protein
C3Z10_RS02520	COG2217	Heavy metal translocating P-type atpase
C3Z10_RS02525	COG3729	General stress protein
C3Z10_RS02530	COG0662	Cupin 2, conserved barrel domain protein
C3Z10_RS02535	COG2329	Antibiotic biosynthesis monooxygenase
C3Z10_RS02540	COG3546	catalase activity
C3Z10_RS02545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C3Z10_RS02550	COG3290	protein histidine kinase activity
C3Z10_RS02555	COG4565	transcriptional regulatory protein
C3Z10_RS02560	COG1301	dicarboxylic acid transport
C3Z10_RS02565	COG0628	permease
C3Z10_RS02570	COG1131	(ABC) transporter
C3Z10_RS02575	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C3Z10_RS02585	COG1960	acyl-CoA dehydrogenase activity
C3Z10_RS02600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C3Z10_RS02605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS02615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C3Z10_RS02620	COG0513	Belongs to the DEAD box helicase family
C3Z10_RS02625	COG3402	PFAM membrane-flanked domain
C3Z10_RS02630	COG3428	Bacterial PH domain
C3Z10_RS02635	COG0705	Rhomboid family
C3Z10_RS02645	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C3Z10_RS02650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3Z10_RS02655	COG0864	Transcriptional regulator
C3Z10_RS02660	COG2337	Toxic component of a toxin-antitoxin (TA) module
C3Z10_RS02665	COG1366	Belongs to the anti-sigma-factor antagonist family
C3Z10_RS02670	COG1366	Belongs to the anti-sigma-factor antagonist family
C3Z10_RS02675	COG2172	sigma factor antagonist activity
C3Z10_RS02680	COG2208	phosphoserine phosphatase activity
C3Z10_RS02685	COG1366	Belongs to the anti-sigma-factor antagonist family
C3Z10_RS02695	COG1191	sigma factor activity
C3Z10_RS02700	COG2208	phosphoserine phosphatase activity
C3Z10_RS02705	COG2183	response to ionizing radiation
C3Z10_RS02755	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3Z10_RS02765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3Z10_RS02770	COG0477	Major facilitator Superfamily
C3Z10_RS02785	COG2030	dehydratase
C3Z10_RS02800	COG1959	2 iron, 2 sulfur cluster binding
C3Z10_RS02805	COG2910	NAD(P)H-binding
C3Z10_RS02810	COG3239	Fatty acid desaturase
C3Z10_RS02820	COG1278	Cold shock
C3Z10_RS02825	COG1329	Transcriptional regulator
C3Z10_RS02830	COG1794	racemase activity, acting on amino acids and derivatives
C3Z10_RS02845	COG3621	Patatin-like phospholipase
C3Z10_RS02855	COG0662	Cupin 2, conserved barrel domain protein
C3Z10_RS02870	COG0277	FAD linked oxidase domain protein
C3Z10_RS02895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C3Z10_RS02930	COG0351	phosphomethylpyrimidine kinase
C3Z10_RS02945	COG1064	alcohol dehydrogenase
C3Z10_RS02950	COG0789	Transcriptional regulator
C3Z10_RS02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3Z10_RS02975	COG2814	Major facilitator Superfamily
C3Z10_RS02980	COG1309	transcriptional regulator
C3Z10_RS02985	COG0697	spore germination
C3Z10_RS02990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3Z10_RS02995	COG5577	PFAM Coat F domain
C3Z10_RS03005	COG1063	alcohol dehydrogenase
C3Z10_RS03010	COG5577	PFAM Coat F domain
C3Z10_RS03025	COG4585	Histidine kinase
C3Z10_RS03030	COG2197	response regulator
C3Z10_RS03035	COG2409	Drug exporters of the RND superfamily
C3Z10_RS03040	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C3Z10_RS03045	COG0488	(ABC) transporter
C3Z10_RS03050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3Z10_RS03055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3Z10_RS03065	COG2814	Major facilitator Superfamily
C3Z10_RS03070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C3Z10_RS03080	COG0730	response to heat
C3Z10_RS03085	COG0456	acetyltransferase
C3Z10_RS03095	COG1051	belongs to the nudix hydrolase family
C3Z10_RS03100	COG2226	methyltransferase
C3Z10_RS03120	COG1802	Transcriptional regulator
C3Z10_RS03125	COG1819	glycosyl
C3Z10_RS03140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3Z10_RS03145	COG1388	LysM domain
C3Z10_RS03150	COG2814	Major facilitator Superfamily
C3Z10_RS03155	COG2188	Transcriptional regulator
C3Z10_RS03160	COG2186	Transcriptional regulator
C3Z10_RS03165	COG2807	transmembrane transport
C3Z10_RS03170	COG2076	Multidrug Resistance protein
C3Z10_RS03175	COG2076	Multidrug Resistance protein
C3Z10_RS03180	COG1309	transcriptional regulator
C3Z10_RS03185	COG0531	amino acid
C3Z10_RS03195	COG3832	glyoxalase III activity
C3Z10_RS03200	COG0604	alcohol dehydrogenase
C3Z10_RS03205	COG2814	Major facilitator Superfamily
C3Z10_RS03245	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C3Z10_RS03250	COG0802	atpase or kinase
C3Z10_RS03255	COG1214	PFAM Peptidase M22, glycoprotease
C3Z10_RS03260	COG0456	acetyltransferase
C3Z10_RS03265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C3Z10_RS03270	COG0488	(ABC) transporter
C3Z10_RS03285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C3Z10_RS03290	COG0805	protein transport
C3Z10_RS03300	COG1266	CAAX protease self-immunity
C3Z10_RS03325	COG0457	Tetratricopeptide repeat
C3Z10_RS03330	COG1063	alcohol dehydrogenase
C3Z10_RS03335	COG2211	Major facilitator Superfamily
C3Z10_RS03340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3Z10_RS03350	COG1842	Phage shock protein A
C3Z10_RS03355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C3Z10_RS03360	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C3Z10_RS03365	COG4260	virion core protein, lumpy skin disease virus
C3Z10_RS03370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C3Z10_RS03370	COG2755	lipolytic protein G-D-S-L family
C3Z10_RS03380	COG1595	DNA-templated transcription, initiation
C3Z10_RS03385	COG1063	alcohol dehydrogenase
C3Z10_RS03390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C3Z10_RS03395	COG0823	Involved in the tonB-independent uptake of proteins
C3Z10_RS03405	COG2132	Multicopper oxidase
C3Z10_RS03410	COG1113	amino acid transport
C3Z10_RS03415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C3Z10_RS03420	COG0714	Associated with various cellular activities
C3Z10_RS03425	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C3Z10_RS03430	COG1305	Transglutaminase-like
C3Z10_RS03455	COG2252	PERMEase
C3Z10_RS03460	COG3064	Membrane
C3Z10_RS03480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C3Z10_RS03485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C3Z10_RS03490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C3Z10_RS03495	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C3Z10_RS03500	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C3Z10_RS03515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C3Z10_RS03525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C3Z10_RS03530	COG0138	bifunctional purine biosynthesis protein purh
C3Z10_RS03535	COG0151	Belongs to the GarS family
C3Z10_RS03545	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C3Z10_RS03550	COG1470	cell adhesion involved in biofilm formation
C3Z10_RS03555	COG4496	protein, YerC YecD
C3Z10_RS03560	COG0069	glutamate synthase activity
C3Z10_RS03575	COG0210	DNA helicase
C3Z10_RS03585	COG4851	CamS sex pheromone cAM373 precursor
C3Z10_RS03590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3Z10_RS03595	COG1285	pathogenesis
C3Z10_RS03600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3Z10_RS03620	COG1309	transcriptional regulator
C3Z10_RS03625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3Z10_RS03630	COG1597	lipid kinase activity
C3Z10_RS03635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C3Z10_RS03690	COG5444	nuclease activity
C3Z10_RS03720	COG3546	catalase activity
C3Z10_RS03725	COG0454	-acetyltransferase
C3Z10_RS03735	COG2323	membrane
C3Z10_RS03740	COG2329	Antibiotic biosynthesis monooxygenase
C3Z10_RS03745	COG0346	lactoylglutathione lyase activity
C3Z10_RS03750	COG1366	Belongs to the anti-sigma-factor antagonist family
C3Z10_RS03755	COG5583	Uncharacterized small protein (DUF2292)
C3Z10_RS03760	COG0196	riboflavin kinase activity
C3Z10_RS03765	COG0670	Belongs to the BI1 family
C3Z10_RS03775	COG1846	Transcriptional regulator
C3Z10_RS03780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3Z10_RS03790	COG2124	cytochrome p450
C3Z10_RS03790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C3Z10_RS03805	COG1131	(ABC) transporter
C3Z10_RS03820	COG1368	sulfuric ester hydrolase activity
C3Z10_RS03825	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C3Z10_RS03830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3Z10_RS03835	COG1442	glycosyl transferase family 8
C3Z10_RS03840	COG1216	Glycosyl transferase, family 2
C3Z10_RS03845	COG1442	glycosyl transferase family 8
C3Z10_RS03850	COG2223	nitrite transmembrane transporter activity
C3Z10_RS03855	COG0531	amino acid
C3Z10_RS03860	COG1012	belongs to the aldehyde dehydrogenase family
C3Z10_RS03865	COG0840	transmembrane signaling receptor activity
C3Z10_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS03875	COG0463	Glycosyl transferase, family 2
C3Z10_RS03875	COG0457	Tetratricopeptide repeat
C3Z10_RS03880	COG0488	(ABC) transporter
C3Z10_RS03885	COG0789	Transcriptional regulator
C3Z10_RS03890	COG2814	Major facilitator Superfamily
C3Z10_RS03895	COG0488	(ABC) transporter
C3Z10_RS03900	COG0513	Belongs to the DEAD box helicase family
C3Z10_RS03905	COG0456	acetyltransferase
C3Z10_RS03910	COG2130	NADP-dependent
C3Z10_RS03925	COG3866	Pectate lyase
C3Z10_RS03930	COG0471	metal ion transport
C3Z10_RS03950	COG2972	Histidine kinase
C3Z10_RS03950	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS03955	COG3279	Response regulator of the LytR AlgR family
C3Z10_RS03965	COG3764	Sortase (surface protein transpeptidase)
C3Z10_RS03970	COG3290	protein histidine kinase activity
C3Z10_RS03975	COG4565	transcriptional regulatory protein
C3Z10_RS03980	COG3181	Tripartite tricarboxylate transporter family receptor
C3Z10_RS03985	COG2851	Citrate transporter
C3Z10_RS03990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3Z10_RS03995	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C3Z10_RS04005	COG2258	MOSC domain
C3Z10_RS04025	COG0024	Methionine aminopeptidase
C3Z10_RS04030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3Z10_RS04030	COG1263	PTS System
C3Z10_RS04040	COG1368	sulfuric ester hydrolase activity
C3Z10_RS04050	COG0071	Belongs to the small heat shock protein (HSP20) family
C3Z10_RS04065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3Z10_RS04065	COG1263	PTS System
C3Z10_RS04070	COG0366	Alpha amylase catalytic
C3Z10_RS04075	COG2188	Transcriptional regulator
C3Z10_RS04080	COG0778	Nitroreductase
C3Z10_RS04095	COG0737	Belongs to the 5'-nucleotidase family
C3Z10_RS04100	COG0693	protein deglycase activity
C3Z10_RS04105	COG1609	Transcriptional regulator
C3Z10_RS04120	COG2814	Major facilitator Superfamily
C3Z10_RS04130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C3Z10_RS04135	COG4980	gas vesicle protein
C3Z10_RS04140	COG1295	ribonuclease BN
C3Z10_RS04145	COG0477	Major facilitator Superfamily
C3Z10_RS04150	COG0387	Pfam Sodium calcium exchanger
C3Z10_RS04160	COG0668	transmembrane transport
C3Z10_RS04165	COG0535	radical SAM domain protein
C3Z10_RS04175	COG0726	polysaccharide deacetylase
C3Z10_RS04180	COG2084	Dehydrogenase
C3Z10_RS04190	COG0598	Magnesium transport protein CorA
C3Z10_RS04195	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C3Z10_RS04200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C3Z10_RS04210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3Z10_RS04220	COG4637	Psort location Cytoplasmic, score
C3Z10_RS04225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3Z10_RS04230	COG0022	dehydrogenase e1 component
C3Z10_RS04235	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3Z10_RS04240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3Z10_RS04245	COG3284	Transcriptional regulator
C3Z10_RS04255	COG1486	melibiose metabolic process
C3Z10_RS04260	COG1737	Transcriptional regulator
C3Z10_RS04265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3Z10_RS04265	COG1263	PTS System
C3Z10_RS04270	COG1132	(ABC) transporter
C3Z10_RS04275	COG1132	(ABC) transporter
C3Z10_RS04280	COG2259	Doxx family
C3Z10_RS04285	COG2514	catechol 2,3-dioxygenase activity
C3Z10_RS04300	COG1695	Transcriptional regulator
C3Z10_RS04305	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3Z10_RS04310	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C3Z10_RS04320	COG3848	Pyruvate phosphate dikinase
C3Z10_RS04320	COG0574	Belongs to the PEP-utilizing enzyme family
C3Z10_RS04325	COG2732	(Barnase) inhibitor
C3Z10_RS04330	COG2318	DinB family
C3Z10_RS04335	COG2814	Major facilitator Superfamily
C3Z10_RS04340	COG1846	Transcriptional regulator
C3Z10_RS04345	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C3Z10_RS04345	COG0392	lysyltransferase activity
C3Z10_RS04350	COG0384	phenazine biosynthesis protein PhzF
C3Z10_RS04355	COG0778	Nitroreductase
C3Z10_RS04370	COG1090	epimerase
C3Z10_RS04385	COG2814	Major facilitator Superfamily
C3Z10_RS04395	COG3591	Belongs to the peptidase S1B family
C3Z10_RS04410	COG3103	Sh3 type 3 domain protein
C3Z10_RS04415	COG5658	integral membrane protein
C3Z10_RS04420	COG0596	Alpha beta hydrolase
C3Z10_RS04425	COG0463	Glycosyl transferase, family 2
C3Z10_RS04430	COG4485	Bacterial membrane protein, YfhO
C3Z10_RS04435	COG1988	membrane-bound metal-dependent
C3Z10_RS04440	COG1194	a g-specific adenine glycosylase
C3Z10_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS04470	COG1132	(ABC) transporter
C3Z10_RS04475	COG4129	membrane
C3Z10_RS04485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C3Z10_RS04490	COG0735	belongs to the Fur family
C3Z10_RS04600	COG1757	Na H antiporter
C3Z10_RS04605	COG3340	Belongs to the peptidase S51 family
C3Z10_RS04615	COG0277	FAD linked oxidase domain protein
C3Z10_RS04625	COG0747	negative chemotaxis
C3Z10_RS04630	COG0601	transmembrane transport
C3Z10_RS04635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3Z10_RS04640	COG0444	Belongs to the ABC transporter superfamily
C3Z10_RS04645	COG4608	Belongs to the ABC transporter superfamily
C3Z10_RS04650	COG0753	catalase activity
C3Z10_RS04660	COG1116	anion transmembrane transporter activity
C3Z10_RS04665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3Z10_RS04670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3Z10_RS04690	COG1476	TRANSCRIPTIONal
C3Z10_RS04700	COG3382	B3 4 domain protein
C3Z10_RS04705	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C3Z10_RS04715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C3Z10_RS04720	COG0789	Transcriptional regulator
C3Z10_RS04725	COG1664	Polymer-forming cytoskeletal
C3Z10_RS04730	COG1664	Polymer-forming cytoskeletal
C3Z10_RS04740	COG2766	serine protein kinase
C3Z10_RS04755	COG1846	Transcriptional regulator
C3Z10_RS04760	COG1566	PFAM secretion protein HlyD family protein
C3Z10_RS04765	COG2814	Major facilitator Superfamily
C3Z10_RS04770	COG0655	NAD(P)H dehydrogenase (quinone) activity
C3Z10_RS04785	COG1725	Transcriptional regulator
C3Z10_RS04790	COG1131	(ABC) transporter
C3Z10_RS04795	COG1131	(ABC) transporter
C3Z10_RS04800	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C3Z10_RS04805	COG1278	Cold shock
C3Z10_RS04815	COG1464	Belongs to the NlpA lipoprotein family
C3Z10_RS04820	COG3706	GGDEF domain
C3Z10_RS04825	COG1823	symporter activity
C3Z10_RS04845	COG5577	PFAM Coat F domain
C3Z10_RS04850	COG0737	Belongs to the 5'-nucleotidase family
C3Z10_RS04850	COG1525	nuclease
C3Z10_RS04850	COG4085	toxin activity
C3Z10_RS04855	COG3764	Sortase (surface protein transpeptidase)
C3Z10_RS04860	COG0564	pseudouridine synthase activity
C3Z10_RS04870	COG0517	IMP dehydrogenase activity
C3Z10_RS04875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C3Z10_RS04880	COG3153	acetyltransferase
C3Z10_RS04880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C3Z10_RS04885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3Z10_RS04890	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C3Z10_RS04895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C3Z10_RS04905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C3Z10_RS04910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C3Z10_RS04920	COG2197	response regulator
C3Z10_RS04925	COG0431	NADPH-dependent FMN reductase
C3Z10_RS04940	COG0791	NLP P60 protein
C3Z10_RS04940	COG1388	LysM domain
C3Z10_RS04945	COG1959	2 iron, 2 sulfur cluster binding
C3Z10_RS04955	COG0668	transmembrane transport
C3Z10_RS04960	COG2719	SpoVR family
C3Z10_RS04965	COG1785	Belongs to the alkaline phosphatase family
C3Z10_RS04970	COG1388	LysM domain
C3Z10_RS04970	COG0791	NLP P60 protein
C3Z10_RS04975	COG0583	DNA-binding transcription factor activity
C3Z10_RS04980	COG0372	Belongs to the citrate synthase family
C3Z10_RS04985	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS04990	COG0531	amino acid
C3Z10_RS04995	COG0733	neurotransmitter:sodium symporter activity
C3Z10_RS05010	COG1595	DNA-templated transcription, initiation
C3Z10_RS05015	COG0204	Acyl-transferase
C3Z10_RS05020	COG1253	flavin adenine dinucleotide binding
C3Z10_RS05025	COG0789	Transcriptional regulator
C3Z10_RS05030	COG0436	Aminotransferase
C3Z10_RS05035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C3Z10_RS05040	COG1253	flavin adenine dinucleotide binding
C3Z10_RS05045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C3Z10_RS05050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C3Z10_RS05055	COG0584	glycerophosphoryl diester phosphodiesterase
C3Z10_RS05065	COG0668	transmembrane transport
C3Z10_RS05070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C3Z10_RS05075	COG0726	polysaccharide deacetylase
C3Z10_RS05080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3Z10_RS05085	COG3226	Transcriptional regulator
C3Z10_RS05095	COG0589	response to stress
C3Z10_RS05100	COG1132	(ABC) transporter
C3Z10_RS05105	COG1132	(ABC) transporter
C3Z10_RS05110	COG0702	epimerase
C3Z10_RS05130	COG0189	ligase activity
C3Z10_RS05135	COG0189	ligase activity
C3Z10_RS05150	COG4335	DNA alkylation repair
C3Z10_RS05155	COG0561	phosphatase activity
C3Z10_RS05160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3Z10_RS05170	COG0475	glutathione-regulated potassium exporter activity
C3Z10_RS05175	COG0490	domain, Protein
C3Z10_RS05185	COG1024	Enoyl-CoA hydratase
C3Z10_RS05195	COG4152	abc transporter atp-binding protein
C3Z10_RS05200	COG1668	transmembrane transport
C3Z10_RS05205	COG0420	3'-5' exonuclease activity
C3Z10_RS05210	COG4717	serine-type aminopeptidase activity
C3Z10_RS05225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3Z10_RS05265	COG4980	gas vesicle protein
C3Z10_RS05280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C3Z10_RS05285	COG0537	adenosine 5'-monophosphoramidase activity
C3Z10_RS05290	COG1131	(ABC) transporter
C3Z10_RS05295	COG4473	ABC transporter
C3Z10_RS05305	COG1473	amidohydrolase
C3Z10_RS05310	COG3069	C4-dicarboxylate transmembrane transporter activity
C3Z10_RS05315	COG2329	Antibiotic biosynthesis monooxygenase
C3Z10_RS05320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3Z10_RS05330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C3Z10_RS05335	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C3Z10_RS05340	COG1309	transcriptional regulator
C3Z10_RS05345	COG1511	domain protein
C3Z10_RS05350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3Z10_RS05360	COG1363	Peptidase, m42
C3Z10_RS05365	COG1301	dicarboxylic acid transport
C3Z10_RS05375	COG1234	tRNA 3'-trailer cleavage
C3Z10_RS05380	COG0095	Lipoate-protein ligase
C3Z10_RS05385	COG0702	epimerase
C3Z10_RS05390	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS05400	COG0501	Belongs to the peptidase M48B family
C3Z10_RS05405	COG1404	Belongs to the peptidase S8 family
C3Z10_RS05415	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C3Z10_RS05420	COG0406	alpha-ribazole phosphatase activity
C3Z10_RS05425	COG0183	Belongs to the thiolase family
C3Z10_RS05430	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS05435	COG1268	BioY protein
C3Z10_RS05440	COG0840	transmembrane signaling receptor activity
C3Z10_RS05445	COG0723	plastoquinol--plastocyanin reductase activity
C3Z10_RS05445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3Z10_RS05450	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS05460	COG4903	ComK protein
C3Z10_RS05470	COG5646	InterPro IPR014922
C3Z10_RS05495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3Z10_RS05510	COG0398	Pfam SNARE associated Golgi protein
C3Z10_RS05515	COG0681	Belongs to the peptidase S26 family
C3Z10_RS05520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3Z10_RS05525	COG1846	Transcriptional regulator
C3Z10_RS05530	COG3180	Ammonia monooxygenase
C3Z10_RS05535	COG2814	Major facilitator Superfamily
C3Z10_RS05545	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C3Z10_RS05550	COG2323	membrane
C3Z10_RS05565	COG0420	3'-5' exonuclease activity
C3Z10_RS05570	COG0419	ATPase involved in DNA repair
C3Z10_RS05575	COG1403	HNH endonuclease
C3Z10_RS05615	COG0179	Fumarylacetoacetate (FAA) hydrolase
C3Z10_RS05635	COG0367	asparagine synthase
C3Z10_RS05640	COG1562	ergosterol biosynthetic process
C3Z10_RS05645	COG0534	Mate efflux family protein
C3Z10_RS05650	COG1917	Cupin 2, conserved barrel domain protein
C3Z10_RS05650	COG2207	Transcriptional regulator
C3Z10_RS05655	COG2318	DinB family
C3Z10_RS05660	COG1279	arginine transmembrane transporter activity
C3Z10_RS05665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3Z10_RS05670	COG1357	PFAM Pentapeptide repeats (8 copies)
C3Z10_RS05675	COG2153	protein acetylation
C3Z10_RS05680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C3Z10_RS05680	COG0646	methionine synthase
C3Z10_RS05690	COG2996	Protein conserved in bacteria
C3Z10_RS05695	COG1744	ABC transporter substrate-binding protein PnrA-like
C3Z10_RS05700	COG0840	transmembrane signaling receptor activity
C3Z10_RS05705	COG2124	cytochrome p450
C3Z10_RS05715	COG1307	EDD domain protein, DegV family
C3Z10_RS05720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3Z10_RS05735	COG0561	phosphatase activity
C3Z10_RS05740	COG1073	alpha beta
C3Z10_RS05745	COG2151	metal-sulfur cluster biosynthetic enzyme
C3Z10_RS05755	COG0277	FAD linked oxidase domain protein
C3Z10_RS05760	COG2271	Major facilitator Superfamily
C3Z10_RS05770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C3Z10_RS05780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C3Z10_RS05785	COG0505	Belongs to the CarA family
C3Z10_RS05790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C3Z10_RS05795	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C3Z10_RS05815	COG2267	carboxylic ester hydrolase activity
C3Z10_RS05825	COG1744	ABC transporter substrate-binding protein PnrA-like
C3Z10_RS05840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3Z10_RS05845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C3Z10_RS05850	COG5504	Zn-dependent protease
C3Z10_RS05855	COG0444	Belongs to the ABC transporter superfamily
C3Z10_RS05860	COG4608	Belongs to the ABC transporter superfamily
C3Z10_RS05870	COG0601	transmembrane transport
C3Z10_RS05875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3Z10_RS05885	COG0180	Tryptophanyl-tRNA synthetase
C3Z10_RS05890	COG4166	transmembrane transport
C3Z10_RS05895	COG0601	transmembrane transport
C3Z10_RS05900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3Z10_RS05905	COG0444	Belongs to the ABC transporter superfamily
C3Z10_RS05910	COG4608	Belongs to the ABC transporter superfamily
C3Z10_RS05920	COG0456	acetyltransferase
C3Z10_RS05925	COG1393	Belongs to the ArsC family
C3Z10_RS05930	COG0861	Integral membrane protein TerC family
C3Z10_RS05935	COG4862	establishment of competence for transformation
C3Z10_RS05940	COG4469	Competence protein
C3Z10_RS05945	COG1164	Oligoendopeptidase f
C3Z10_RS05950	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C3Z10_RS05955	COG2346	COG2346, Truncated hemoglobins
C3Z10_RS05960	COG0741	lytic transglycosylase activity
C3Z10_RS05965	COG4116	CYTH
C3Z10_RS05975	COG2357	RelA SpoT domain protein
C3Z10_RS05980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C3Z10_RS05985	COG0564	pseudouridine synthase activity
C3Z10_RS06000	COG0569	domain protein
C3Z10_RS06000	COG0475	glutathione-regulated potassium exporter activity
C3Z10_RS06005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C3Z10_RS06010	COG0352	thiamine-phosphate diphosphorylase activity
C3Z10_RS06015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3Z10_RS06020	COG2104	thiamine diphosphate biosynthetic process
C3Z10_RS06030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3Z10_RS06035	COG0351	phosphomethylpyrimidine kinase
C3Z10_RS06040	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C3Z10_RS06095	COG0210	DNA helicase
C3Z10_RS06115	COG1131	(ABC) transporter
C3Z10_RS06125	COG2153	protein acetylation
C3Z10_RS06135	COG2382	esterase
C3Z10_RS06140	COG0626	cystathionine gamma-synthase activity
C3Z10_RS06145	COG0626	cystathionine gamma-synthase activity
C3Z10_RS06180	COG5444	nuclease activity
C3Z10_RS06270	COG0537	adenosine 5'-monophosphoramidase activity
C3Z10_RS06275	COG0135	phosphoribosylanthranilate isomerase activity
C3Z10_RS06290	COG2367	Beta-lactamase
C3Z10_RS06295	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C3Z10_RS06300	COG0477	Major facilitator Superfamily
C3Z10_RS06305	COG1846	Transcriptional regulator
C3Z10_RS06315	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C3Z10_RS06320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3Z10_RS06325	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C3Z10_RS06330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3Z10_RS06330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3Z10_RS06335	COG1447	Phosphotransferase system cellobiose-specific component IIA
C3Z10_RS06370	COG1285	pathogenesis
C3Z10_RS06385	COG2205	protein histidine kinase activity
C3Z10_RS06395	COG3383	formate dehydrogenase (NAD+) activity
C3Z10_RS06400	COG2427	Protein of unknown function (DUF1641)
C3Z10_RS06405	COG2124	cytochrome p450
C3Z10_RS06410	COG1819	glycosyl
C3Z10_RS06420	COG1587	Uroporphyrinogen-III synthase
C3Z10_RS06425	COG0390	transport system, permease component
C3Z10_RS06430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C3Z10_RS06435	COG0697	spore germination
C3Z10_RS06440	COG4297	protein containing double-stranded beta helix domain
C3Z10_RS06450	COG1252	NADH dehydrogenase
C3Z10_RS06460	COG2211	Major facilitator Superfamily
C3Z10_RS06465	COG1609	Transcriptional regulator
C3Z10_RS06470	COG0246	Mannitol dehydrogenase
C3Z10_RS06475	COG2721	sulfolactate sulfo-lyase activity
C3Z10_RS06480	COG0730	response to heat
C3Z10_RS06485	COG2318	DinB family
C3Z10_RS06490	COG0457	Tetratricopeptide repeat
C3Z10_RS06495	COG5632	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS06495	COG3409	Peptidoglycan-binding domain 1 protein
C3Z10_RS06495	COG1388	LysM domain
C3Z10_RS06505	COG4195	phage-related replication protein
C3Z10_RS06510	COG3546	catalase activity
C3Z10_RS06515	COG2856	Zn peptidase
C3Z10_RS06525	COG1396	sequence-specific DNA binding
C3Z10_RS06535	COG1522	sequence-specific DNA binding
C3Z10_RS06540	COG1484	DNA-dependent DNA replication
C3Z10_RS06555	COG1595	DNA-templated transcription, initiation
C3Z10_RS06560	COG5484	DNA packaging
C3Z10_RS06560	COG3728	DNA packaging
C3Z10_RS06565	COG1783	phage Terminase large subunit
C3Z10_RS06570	COG5518	Phage portal protein
C3Z10_RS06575	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C3Z10_RS06580	COG4653	Phage capsid family
C3Z10_RS06630	COG3953	SLT domain
C3Z10_RS06630	COG5412	phage tail tape measure protein
C3Z10_RS06630	COG3953	SLT domain
C3Z10_RS06630	COG5412	phage tail tape measure protein
C3Z10_RS06630	COG5412	phage tail tape measure protein
C3Z10_RS06630	COG3953	SLT domain
C3Z10_RS06635	COG1652	LysM domain
C3Z10_RS06640	COG4193	domain, Protein
C3Z10_RS06650	COG3628	GPW Gp25 family protein
C3Z10_RS06655	COG3299	homolog of phage Mu protein gp47
C3Z10_RS06660	COG3778	Protein conserved in bacteria
C3Z10_RS06700	COG3409	Peptidoglycan-binding domain 1 protein
C3Z10_RS06700	COG5632	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS06715	COG0306	phosphate transporter
C3Z10_RS06720	COG1392	Phosphate transport regulator
C3Z10_RS06725	COG0531	amino acid
C3Z10_RS06730	COG0346	lactoylglutathione lyase activity
C3Z10_RS06735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C3Z10_RS06740	COG0463	Glycosyl transferase, family 2
C3Z10_RS06750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3Z10_RS06755	COG0477	Major facilitator Superfamily
C3Z10_RS06760	COG2362	D-Aminopeptidase
C3Z10_RS06765	COG0601	transmembrane transport
C3Z10_RS06770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3Z10_RS06775	COG0444	Belongs to the ABC transporter superfamily
C3Z10_RS06780	COG4166	transmembrane transport
C3Z10_RS06785	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3Z10_RS06790	COG4948	Mandelate Racemase Muconate Lactonizing
C3Z10_RS06795	COG0791	NLP P60 protein
C3Z10_RS06800	COG4608	Belongs to the ABC transporter superfamily
C3Z10_RS06805	COG2706	6-phosphogluconolactonase activity
C3Z10_RS06810	COG1834	amidinotransferase
C3Z10_RS06815	COG1607	acyl-coa hydrolase
C3Z10_RS06820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3Z10_RS06825	COG2076	Multidrug Resistance protein
C3Z10_RS06830	COG2076	Multidrug Resistance protein
C3Z10_RS06835	COG0788	formyltetrahydrofolate deformylase activity
C3Z10_RS06840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C3Z10_RS06850	COG1764	response to oxidative stress
C3Z10_RS06855	COG1846	Transcriptional regulator
C3Z10_RS06860	COG1764	response to oxidative stress
C3Z10_RS06875	COG0463	Glycosyl transferase, family 2
C3Z10_RS06875	COG0457	Tetratricopeptide repeat
C3Z10_RS06885	COG2814	Major facilitator Superfamily
C3Z10_RS06890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C3Z10_RS06900	COG1404	Belongs to the peptidase S8 family
C3Z10_RS06905	COG1366	Belongs to the anti-sigma-factor antagonist family
C3Z10_RS06910	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C3Z10_RS06915	COG1122	ATPase activity
C3Z10_RS06920	COG4721	ABC-type cobalt transport system, permease component
C3Z10_RS06925	COG3858	chitin binding
C3Z10_RS06925	COG1388	LysM domain
C3Z10_RS06940	COG2239	Acts as a magnesium transporter
C3Z10_RS06945	COG0789	Transcriptional regulator
C3Z10_RS06960	COG1846	Transcriptional regulator
C3Z10_RS06965	COG0726	polysaccharide deacetylase
C3Z10_RS06970	COG3285	dna ligase
C3Z10_RS06970	COG1793	dna ligase
C3Z10_RS06975	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C3Z10_RS06980	COG0586	Pfam SNARE associated Golgi protein
C3Z10_RS06985	COG0861	Integral membrane protein TerC family
C3Z10_RS06990	COG1191	sigma factor activity
C3Z10_RS07015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3Z10_RS07020	COG2323	membrane
C3Z10_RS07030	COG3594	Acyltransferase
C3Z10_RS07035	COG5002	protein histidine kinase activity
C3Z10_RS07040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C3Z10_RS07055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C3Z10_RS07060	COG0436	Aminotransferase
C3Z10_RS07090	COG3852	Histidine kinase
C3Z10_RS07095	COG1846	Transcriptional regulator
C3Z10_RS07100	COG1360	Flagellar Motor Protein
C3Z10_RS07105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C3Z10_RS07110	COG0542	response to heat
C3Z10_RS07120	COG3949	Membrane
C3Z10_RS07135	COG0720	synthase
C3Z10_RS07140	COG0602	queuosine metabolic process
C3Z10_RS07150	COG1733	regulation of RNA biosynthetic process
C3Z10_RS07155	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS07165	COG1388	LysM domain
C3Z10_RS07165	COG4641	Protein conserved in bacteria
C3Z10_RS07170	COG1388	LysM domain
C3Z10_RS07175	COG3858	chitin binding
C3Z10_RS07190	COG4873	Protein conserved in bacteria
C3Z10_RS07200	COG3773	Cell wall hydrolase
C3Z10_RS07205	COG2244	polysaccharide biosynthetic process
C3Z10_RS07210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS07215	COG2217	Heavy metal translocating P-type atpase
C3Z10_RS07220	COG0006	proline dipeptidase activity
C3Z10_RS07225	COG1609	Transcriptional regulator
C3Z10_RS07230	COG3711	transcriptional antiterminator
C3Z10_RS07235	COG2190	(PTS) system
C3Z10_RS07235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3Z10_RS07235	COG1263	PTS System
C3Z10_RS07240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3Z10_RS07245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C3Z10_RS07255	COG1533	DNA photolyase activity
C3Z10_RS07260	COG0840	transmembrane signaling receptor activity
C3Z10_RS07265	COG2084	Dehydrogenase
C3Z10_RS07270	COG2340	Cysteine-rich secretory protein family
C3Z10_RS07275	COG0768	penicillin binding
C3Z10_RS07280	COG4191	Histidine kinase
C3Z10_RS07285	COG0436	Aminotransferase
C3Z10_RS07295	COG0784	Response regulator, receiver
C3Z10_RS07295	COG0835	chemotaxis
C3Z10_RS07305	COG2814	Major facilitator Superfamily
C3Z10_RS07310	COG1376	ErfK ybiS ycfS ynhG family protein
C3Z10_RS07315	COG1408	metallophosphoesterase
C3Z10_RS07320	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS07330	COG2200	EAL domain
C3Z10_RS07335	COG4703	Protein of unknown function (DUF1797)
C3Z10_RS07340	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C3Z10_RS07350	COG0517	IMP dehydrogenase activity
C3Z10_RS07355	COG0583	DNA-binding transcription factor activity
C3Z10_RS07360	COG0716	FMN binding
C3Z10_RS07370	COG0716	FMN binding
C3Z10_RS07390	COG0668	transmembrane transport
C3Z10_RS07395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS07415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3Z10_RS07420	COG0303	'Molybdopterin
C3Z10_RS07425	COG1763	Mo-molybdopterin cofactor biosynthetic process
C3Z10_RS07430	COG0314	molybdopterin synthase activity
C3Z10_RS07435	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C3Z10_RS07445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3Z10_RS07450	COG1136	(ABC) transporter
C3Z10_RS07455	COG0577	efflux transmembrane transporter activity
C3Z10_RS07460	COG1349	DNA-binding transcription factor activity
C3Z10_RS07465	COG1105	Belongs to the carbohydrate kinase PfkB family
C3Z10_RS07470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3Z10_RS07470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3Z10_RS07470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3Z10_RS07475	COG0681	Belongs to the peptidase S26 family
C3Z10_RS07485	COG0488	(ABC) transporter
C3Z10_RS07490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C3Z10_RS07495	COG2309	aminopeptidase activity
C3Z10_RS07505	COG1077	Cell shape determining protein MreB Mrl
C3Z10_RS07515	COG2002	toxin-antitoxin pair type II binding
C3Z10_RS07520	COG3852	Histidine kinase
C3Z10_RS07525	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C3Z10_RS07525	COG2105	PFAM AIG2 family protein
C3Z10_RS07530	COG0569	domain protein
C3Z10_RS07540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C3Z10_RS07550	COG0561	phosphatase activity
C3Z10_RS07555	COG0242	peptide deformylase activity
C3Z10_RS07565	COG0497	DNA recombination
C3Z10_RS07580	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS07580	COG4221	oxidoreductase activity
C3Z10_RS07580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS07580	COG3321	synthase
C3Z10_RS07585	COG4221	oxidoreductase activity
C3Z10_RS07585	COG3321	synthase
C3Z10_RS07585	COG0300	oxidoreductase activity
C3Z10_RS07585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS07590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS07590	COG4221	oxidoreductase activity
C3Z10_RS07590	COG3321	synthase
C3Z10_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS07595	COG3321	synthase
C3Z10_RS07595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS07595	COG0300	oxidoreductase activity
C3Z10_RS07595	COG4221	oxidoreductase activity
C3Z10_RS07600	COG4221	oxidoreductase activity
C3Z10_RS07600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS07600	COG3321	synthase
C3Z10_RS07600	COG0300	oxidoreductase activity
C3Z10_RS07605	COG4221	oxidoreductase activity
C3Z10_RS07605	COG3321	synthase
C3Z10_RS07605	COG0300	oxidoreductase activity
C3Z10_RS07605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS07610	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS07610	COG3321	synthase
C3Z10_RS07610	COG4221	oxidoreductase activity
C3Z10_RS07610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS07615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3Z10_RS07620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3Z10_RS07625	COG0022	dehydrogenase e1 component
C3Z10_RS07630	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3Z10_RS07635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3Z10_RS07640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS07655	COG1982	Orn Lys Arg decarboxylase major
C3Z10_RS07680	COG0483	inositol monophosphate 1-phosphatase activity
C3Z10_RS07690	COG3227	Zinc metalloprotease (Elastase)
C3Z10_RS07705	COG1595	DNA-templated transcription, initiation
C3Z10_RS07725	COG1217	gtp-binding protein TYPA
C3Z10_RS07735	COG4896	Protein conserved in bacteria
C3Z10_RS07745	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C3Z10_RS07750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C3Z10_RS07835	COG0457	Tetratricopeptide repeat
C3Z10_RS07860	COG1196	nuclear chromosome segregation
C3Z10_RS07860	COG0741	lytic transglycosylase activity
C3Z10_RS07860	COG0739	heme binding
C3Z10_RS07980	COG2066	Belongs to the glutaminase family
C3Z10_RS07990	COG0772	Belongs to the SEDS family
C3Z10_RS07995	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C3Z10_RS08010	COG2010	Cytochrome c
C3Z10_RS08010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C3Z10_RS08015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C3Z10_RS08020	COG1845	cytochrome c oxidase, subunit III
C3Z10_RS08025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C3Z10_RS08030	COG3336	cytochrome c oxidase
C3Z10_RS08040	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C3Z10_RS08045	COG2340	Cysteine-rich secretory protein family
C3Z10_RS08060	COG3679	Belongs to the UPF0342 family
C3Z10_RS08070	COG0742	ribosomal rna small subunit methyltransferase
C3Z10_RS08080	COG3314	Sporulation integral membrane protein YlbJ
C3Z10_RS08085	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3Z10_RS08090	COG3480	Lon protease (S16) C-terminal proteolytic domain
C3Z10_RS08100	COG1399	metal-binding, possibly nucleic acid-binding protein
C3Z10_RS08120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C3Z10_RS08140	COG4839	cell division protein FtsL
C3Z10_RS08145	COG0768	penicillin binding
C3Z10_RS08150	COG0768	penicillin binding
C3Z10_RS08170	COG0772	Belongs to the SEDS family
C3Z10_RS08185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C3Z10_RS08190	COG0849	cell division
C3Z10_RS08195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C3Z10_RS08200	COG1404	Belongs to the peptidase S8 family
C3Z10_RS08200	COG4412	M6 family metalloprotease domain protein
C3Z10_RS08210	COG1191	sigma factor activity
C3Z10_RS08215	COG1191	sigma factor activity
C3Z10_RS08220	COG1119	ATPase activity
C3Z10_RS08225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3Z10_RS08230	COG1873	PFAM PRC-barrel domain
C3Z10_RS08235	COG1496	oxidoreductase activity
C3Z10_RS08240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C3Z10_RS08250	COG0762	integral membrane protein
C3Z10_RS08255	COG2302	S4 RNA-binding domain
C3Z10_RS08260	COG3599	regulation of cell shape
C3Z10_RS08270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C3Z10_RS08275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C3Z10_RS08285	COG0564	pseudouridine synthase activity
C3Z10_RS08295	COG2233	PERMEase
C3Z10_RS08305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C3Z10_RS08310	COG0505	Belongs to the CarA family
C3Z10_RS08315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C3Z10_RS08330	COG0284	orotidine-5'-phosphate decarboxylase activity
C3Z10_RS08335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C3Z10_RS08345	COG0306	phosphate transporter
C3Z10_RS08360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C3Z10_RS08365	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C3Z10_RS08370	COG1648	precorrin-2 dehydrogenase activity
C3Z10_RS08385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C3Z10_RS08390	COG1561	YicC-like family, N-terminal region
C3Z10_RS08400	COG0194	GDP metabolic process
C3Z10_RS08410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C3Z10_RS08415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C3Z10_RS08420	COG0242	peptide deformylase activity
C3Z10_RS08430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C3Z10_RS08430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C3Z10_RS08440	COG0631	protein serine/threonine phosphatase activity
C3Z10_RS08445	COG0515	serine threonine protein kinase
C3Z10_RS08445	COG2815	serine threonine protein kinase
C3Z10_RS08455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C3Z10_RS08460	COG1564	THIamine pyrophosphokinase
C3Z10_RS08475	COG1302	Protein conserved in bacteria
C3Z10_RS08480	COG1461	Dihydroxyacetone kinase
C3Z10_RS08485	COG1760	l-serine dehydratase
C3Z10_RS08490	COG1760	l-serine dehydratase
C3Z10_RS08495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C3Z10_RS08510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C3Z10_RS08515	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS08530	COG1196	nuclear chromosome segregation
C3Z10_RS08535	COG0552	protein localization to endoplasmic reticulum
C3Z10_RS08550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C3Z10_RS08560	COG1837	Belongs to the UPF0109 family
C3Z10_RS08585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C3Z10_RS08600	COG2257	FlhB HrpN YscU SpaS Family
C3Z10_RS08610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C3Z10_RS08615	COG0758	DNA mediated transformation
C3Z10_RS08620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C3Z10_RS08630	COG4974	Belongs to the 'phage' integrase family
C3Z10_RS08650	COG1815	bacterial-type flagellum-dependent cell motility
C3Z10_RS08655	COG1558	bacterial-type flagellum-dependent cell motility
C3Z10_RS08660	COG1677	Flagellar hook-basal body complex protein FliE
C3Z10_RS08665	COG1766	The M ring may be actively involved in energy transduction
C3Z10_RS08670	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3Z10_RS08675	COG1317	bacterial-type flagellum organization
C3Z10_RS08680	COG1157	protein secretion by the type III secretion system
C3Z10_RS08685	COG2882	bacterial-type flagellum organization
C3Z10_RS08690	COG3334	PFAM MgtE intracellular
C3Z10_RS08695	COG3144	bacterial-type flagellum assembly
C3Z10_RS08700	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C3Z10_RS08705	COG4786	Flagellar basal body rod
C3Z10_RS08710	COG1582	Flagellar protein (FlbD)
C3Z10_RS08715	COG1580	Controls the rotational direction of flagella during chemotaxis
C3Z10_RS08720	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3Z10_RS08725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3Z10_RS08725	COG1776	CheC inhibitor of MCP methylation
C3Z10_RS08730	COG2201	protein-glutamate methylesterase activity
C3Z10_RS08735	COG3190	flagellar
C3Z10_RS08740	COG1338	Plays a role in the flagellum-specific transport system
C3Z10_RS08745	COG1987	bacterial-type flagellum assembly
C3Z10_RS08750	COG1684	flagellar biosynthetic protein fliR
C3Z10_RS08755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C3Z10_RS08760	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C3Z10_RS08765	COG1419	protein localization to endoplasmic reticulum
C3Z10_RS08770	COG0455	bacterial-type flagellum organization
C3Z10_RS08775	COG2201	protein-glutamate methylesterase activity
C3Z10_RS08780	COG2198	Histidine kinase
C3Z10_RS08780	COG0643	Histidine kinase
C3Z10_RS08785	COG0835	chemotaxis
C3Z10_RS08790	COG1776	CheC inhibitor of MCP methylation
C3Z10_RS08800	COG1191	sigma factor activity
C3Z10_RS08830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C3Z10_RS08835	COG4589	Belongs to the CDS family
C3Z10_RS08845	COG0750	zinc metalloprotease
C3Z10_RS08855	COG2176	DNA-directed DNA polymerase activity
C3Z10_RS08865	COG0195	Participates in both transcription termination and antitermination
C3Z10_RS08870	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C3Z10_RS08875	COG1358	cellular component organization or biogenesis
C3Z10_RS08885	COG1550	Protein conserved in bacteria
C3Z10_RS08900	COG0196	riboflavin kinase activity
C3Z10_RS08915	COG0726	polysaccharide deacetylase
C3Z10_RS08920	COG0612	Peptidase, M16
C3Z10_RS08925	COG1873	PFAM PRC-barrel domain
C3Z10_RS08930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3Z10_RS08935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C3Z10_RS08940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C3Z10_RS08945	COG0527	aspartate kinase activity
C3Z10_RS08955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C3Z10_RS08960	COG0740	serine-type endopeptidase activity
C3Z10_RS08970	COG4980	gas vesicle protein
C3Z10_RS08970	COG1674	ftsk spoiiie
C3Z10_RS08975	COG2188	Transcriptional regulator
C3Z10_RS08980	COG2814	Major facilitator Superfamily
C3Z10_RS08985	COG1846	Transcriptional regulator
C3Z10_RS08990	COG1033	growth of symbiont in host cell
C3Z10_RS08990	COG2409	Drug exporters of the RND superfamily
C3Z10_RS08995	COG0612	Peptidase, M16
C3Z10_RS09000	COG0612	Peptidase, M16
C3Z10_RS09005	COG0300	oxidoreductase activity
C3Z10_RS09020	COG1426	Protein conserved in bacteria
C3Z10_RS09025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C3Z10_RS09040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3Z10_RS09050	COG1692	metallophosphoesterase
C3Z10_RS09055	COG2359	stage V sporulation protein S
C3Z10_RS09075	COG4550	Control of competence regulator ComK, YlbF/YmcA
C3Z10_RS09095	COG0582	viral genome integration into host DNA
C3Z10_RS09135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS09140	COG3425	synthase
C3Z10_RS09145	COG1024	Enoyl-CoA hydratase
C3Z10_RS09150	COG1024	Enoyl-CoA hydratase
C3Z10_RS09155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS09155	COG3321	synthase
C3Z10_RS09155	COG0300	oxidoreductase activity
C3Z10_RS09155	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS09160	COG4221	oxidoreductase activity
C3Z10_RS09160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS09160	COG0300	oxidoreductase activity
C3Z10_RS09160	COG3321	synthase
C3Z10_RS09165	COG3321	synthase
C3Z10_RS09165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS09165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3Z10_RS09165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS09165	COG3321	synthase
C3Z10_RS09165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS09165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3Z10_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS09165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS09170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS09170	COG3321	synthase
C3Z10_RS09170	COG4221	oxidoreductase activity
C3Z10_RS09175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C3Z10_RS09175	COG3321	synthase
C3Z10_RS09175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C3Z10_RS09175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS09180	COG2124	cytochrome p450
C3Z10_RS09185	COG3209	COG3209 Rhs family protein
C3Z10_RS09190	COG3619	membrane
C3Z10_RS09200	COG1404	Belongs to the peptidase S8 family
C3Z10_RS09210	COG4195	phage-related replication protein
C3Z10_RS09215	COG1764	response to oxidative stress
C3Z10_RS09225	COG2076	Multidrug Resistance protein
C3Z10_RS09265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3Z10_RS09270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3Z10_RS09275	COG4112	unkown
C3Z10_RS09280	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS09290	COG0464	growth
C3Z10_RS09295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C3Z10_RS09300	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C3Z10_RS09305	COG0789	Transcriptional regulator
C3Z10_RS09310	COG0174	glutamine synthetase
C3Z10_RS09325	COG4282	regulation of fungal-type cell wall biogenesis
C3Z10_RS09350	COG2211	Major facilitator Superfamily
C3Z10_RS09355	COG3507	Belongs to the glycosyl hydrolase 43 family
C3Z10_RS09370	COG1070	Carbohydrate kinase
C3Z10_RS09375	COG3848	Pyruvate phosphate dikinase
C3Z10_RS09375	COG0574	Belongs to the PEP-utilizing enzyme family
C3Z10_RS09405	COG1064	alcohol dehydrogenase
C3Z10_RS09430	COG0456	acetyltransferase
C3Z10_RS09450	COG3397	chitin binding
C3Z10_RS09460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3Z10_RS09470	COG5434	Belongs to the glycosyl hydrolase 28 family
C3Z10_RS09475	COG0756	dUTP diphosphatase activity
C3Z10_RS09485	COG4195	phage-related replication protein
C3Z10_RS09515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C3Z10_RS09525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C3Z10_RS09545	COG0785	Cytochrome C biogenesis protein
C3Z10_RS09550	COG2201	protein-glutamate methylesterase activity
C3Z10_RS09555	COG4846	Membrane protein involved in cytochrome C biogenesis
C3Z10_RS09565	COG0071	Belongs to the small heat shock protein (HSP20) family
C3Z10_RS09580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C3Z10_RS09585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS09605	COG0824	Thioesterase
C3Z10_RS09615	COG4841	protein insertion into membrane
C3Z10_RS09625	COG1832	CoA-binding protein
C3Z10_RS09630	COG0187	DNA topoisomerase II activity
C3Z10_RS09635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C3Z10_RS09645	COG1115	amino acid carrier protein
C3Z10_RS09655	COG1063	alcohol dehydrogenase
C3Z10_RS09660	COG0800	Aldolase
C3Z10_RS09665	COG1312	Catalyzes the dehydration of D-mannonate
C3Z10_RS09670	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS09675	COG1609	Transcriptional regulator
C3Z10_RS09680	COG2271	Major facilitator Superfamily
C3Z10_RS09720	COG0457	Tetratricopeptide repeat
C3Z10_RS09745	COG0577	efflux transmembrane transporter activity
C3Z10_RS09745	COG1136	(ABC) transporter
C3Z10_RS09775	COG2205	protein histidine kinase activity
C3Z10_RS09780	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS09790	COG3507	Belongs to the glycosyl hydrolase 43 family
C3Z10_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS09825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3Z10_RS09830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C3Z10_RS09835	COG2610	gluconate transmembrane transporter activity
C3Z10_RS09840	COG2124	cytochrome p450
C3Z10_RS09860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3Z10_RS09870	COG2246	polysaccharide biosynthetic process
C3Z10_RS09875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C3Z10_RS09880	COG0586	Pfam SNARE associated Golgi protein
C3Z10_RS09885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C3Z10_RS09890	COG1024	Enoyl-CoA hydratase
C3Z10_RS09895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C3Z10_RS09900	COG0511	ligase activity, forming carbon-carbon bonds
C3Z10_RS09905	COG0439	Biotin carboxylase
C3Z10_RS09910	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS09915	COG1960	acyl-CoA dehydrogenase activity
C3Z10_RS09920	COG1649	PFAM Uncharacterised BCR, COG1649
C3Z10_RS09930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS09930	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C3Z10_RS09935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS09940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS09945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS09950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS09960	COG2027	D-alanyl-D-alanine carboxypeptidase
C3Z10_RS09965	COG2017	converts alpha-aldose to the beta-anomer
C3Z10_RS09970	COG0534	Mate efflux family protein
C3Z10_RS09980	COG5444	nuclease activity
C3Z10_RS09995	COG3409	Peptidoglycan-binding domain 1 protein
C3Z10_RS09995	COG5632	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS10000	COG4824	toxin secretion phage lysis holin
C3Z10_RS10020	COG5434	Belongs to the glycosyl hydrolase 28 family
C3Z10_RS10025	COG1705	Flagellar rod assembly protein muramidase FlgJ
C3Z10_RS10025	COG1388	LysM domain
C3Z10_RS10105	COG1802	Transcriptional regulator
C3Z10_RS10105	COG4626	Terminase
C3Z10_RS10145	COG0582	viral genome integration into host DNA
C3Z10_RS10150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C3Z10_RS10155	COG1595	DNA-templated transcription, initiation
C3Z10_RS10255	COG0582	viral genome integration into host DNA
C3Z10_RS10260	COG0166	Belongs to the GPI family
C3Z10_RS10265	COG0405	Gamma-glutamyltransferase
C3Z10_RS10270	COG2814	Major facilitator Superfamily
C3Z10_RS10275	COG0640	Transcriptional regulator
C3Z10_RS10280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C3Z10_RS10290	COG0604	alcohol dehydrogenase
C3Z10_RS10295	COG0493	'glutamate synthase
C3Z10_RS10300	COG0070	glutamate synthase
C3Z10_RS10300	COG0069	glutamate synthase activity
C3Z10_RS10300	COG0067	glutamate synthase
C3Z10_RS10305	COG0583	DNA-binding transcription factor activity
C3Z10_RS10310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C3Z10_RS10325	COG0300	oxidoreductase activity
C3Z10_RS10330	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C3Z10_RS10340	COG2814	Major facilitator Superfamily
C3Z10_RS10345	COG1070	Carbohydrate kinase
C3Z10_RS10350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3Z10_RS10355	COG0243	molybdopterin cofactor binding
C3Z10_RS10385	COG5444	nuclease activity
C3Z10_RS10390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3Z10_RS10395	COG0662	Cupin 2, conserved barrel domain protein
C3Z10_RS10395	COG2207	Transcriptional regulator
C3Z10_RS10400	COG1309	transcriptional regulator
C3Z10_RS10405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3Z10_RS10415	COG0640	Transcriptional regulator
C3Z10_RS10420	COG0741	lytic transglycosylase activity
C3Z10_RS10425	COG2322	membrane
C3Z10_RS10440	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3Z10_RS10450	COG3584	3D domain protein
C3Z10_RS10450	COG1388	LysM domain
C3Z10_RS10455	COG0514	ATP-dependent DNA helicase (RecQ)
C3Z10_RS10465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C3Z10_RS10470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C3Z10_RS10485	COG0071	Belongs to the small heat shock protein (HSP20) family
C3Z10_RS10515	COG1012	belongs to the aldehyde dehydrogenase family
C3Z10_RS10520	COG1657	PFAM Prenyltransferase squalene oxidase
C3Z10_RS10525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3Z10_RS10530	COG0733	neurotransmitter:sodium symporter activity
C3Z10_RS10535	COG0385	Bile acid
C3Z10_RS10540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3Z10_RS10545	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3Z10_RS10555	COG4548	von Willebrand factor, type A
C3Z10_RS10560	COG0714	Associated with various cellular activities
C3Z10_RS10565	COG2032	superoxide dismutase activity
C3Z10_RS10570	COG0791	NLP P60 protein
C3Z10_RS10570	COG1388	LysM domain
C3Z10_RS10575	COG1819	glycosyl
C3Z10_RS10580	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C3Z10_RS10585	COG0534	Mate efflux family protein
C3Z10_RS10590	COG1366	Belongs to the anti-sigma-factor antagonist family
C3Z10_RS10595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3Z10_RS10600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3Z10_RS10610	COG2962	Rard protein
C3Z10_RS10625	COG1942	4-Oxalocrotonate Tautomerase
C3Z10_RS10635	COG1733	regulation of RNA biosynthetic process
C3Z10_RS10640	COG0778	Nitroreductase
C3Z10_RS10645	COG0400	carboxylic ester hydrolase activity
C3Z10_RS10650	COG0346	lactoylglutathione lyase activity
C3Z10_RS10660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3Z10_RS10670	COG2723	6-phospho-beta-galactosidase activity
C3Z10_RS10675	COG2188	Transcriptional regulator
C3Z10_RS10680	COG0793	Belongs to the peptidase S41A family
C3Z10_RS10680	COG3409	Peptidoglycan-binding domain 1 protein
C3Z10_RS10685	COG2226	methyltransferase
C3Z10_RS10695	COG1876	peptidase activity
C3Z10_RS10715	COG0671	phosphoesterase, PA-phosphatase related
C3Z10_RS10745	COG1509	lysine 2,3-aminomutase activity
C3Z10_RS10750	COG0456	acetyltransferase
C3Z10_RS10755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3Z10_RS10760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3Z10_RS10765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C3Z10_RS10770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3Z10_RS10775	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C3Z10_RS10785	COG0456	acetyltransferase
C3Z10_RS10790	COG0463	Glycosyl transferase, family 2
C3Z10_RS10805	COG4641	Protein conserved in bacteria
C3Z10_RS10815	COG1086	Polysaccharide biosynthesis protein
C3Z10_RS10875	COG1388	LysM domain
C3Z10_RS10885	COG0457	Tetratricopeptide repeat
C3Z10_RS10905	COG5444	nuclease activity
C3Z10_RS10910	COG4282	regulation of fungal-type cell wall biogenesis
C3Z10_RS10915	COG1525	nuclease
C3Z10_RS10920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C3Z10_RS10940	COG1846	Transcriptional regulator
C3Z10_RS10945	COG4698	Protein conserved in bacteria
C3Z10_RS10950	COG2755	lipolytic protein G-D-S-L family
C3Z10_RS10955	COG1999	signal sequence binding
C3Z10_RS10965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C3Z10_RS10970	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C3Z10_RS10975	COG1272	protein, Hemolysin III
C3Z10_RS10980	COG0204	Acyl-transferase
C3Z10_RS10985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C3Z10_RS11000	COG2136	Putative SAM-dependent methyltransferase
C3Z10_RS11000	COG2521	methyltransferase
C3Z10_RS11015	COG1413	lyase activity
C3Z10_RS11025	COG0386	Belongs to the glutathione peroxidase family
C3Z10_RS11035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C3Z10_RS11040	COG1278	Cold shock
C3Z10_RS11060	COG0328	RNA-DNA hybrid ribonuclease activity
C3Z10_RS11065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C3Z10_RS11070	COG0328	RNA-DNA hybrid ribonuclease activity
C3Z10_RS11080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3Z10_RS11095	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C3Z10_RS11105	COG1755	Isoprenylcysteine carboxyl methyltransferase
C3Z10_RS11110	COG3424	synthase
C3Z10_RS11135	COG1335	isochorismatase
C3Z10_RS11150	COG3331	DNA recombination
C3Z10_RS11250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C3Z10_RS11255	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C3Z10_RS11275	COG4112	unkown
C3Z10_RS11290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS11295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3Z10_RS11305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3Z10_RS11395	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C3Z10_RS11405	COG3584	3D domain protein
C3Z10_RS11410	COG0587	DNA-directed DNA polymerase activity
C3Z10_RS11415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C3Z10_RS11420	COG0358	DNA primase activity
C3Z10_RS11425	COG0305	Participates in initiation and elongation during chromosome replication
C3Z10_RS11435	COG2887	Belongs to the helicase family. UvrD subfamily
C3Z10_RS11465	COG5434	Belongs to the glycosyl hydrolase 28 family
C3Z10_RS11465	COG3420	alginic acid biosynthetic process
C3Z10_RS11470	COG4195	phage-related replication protein
C3Z10_RS11490	COG2135	peptidase activity
C3Z10_RS11495	COG1793	dna ligase
C3Z10_RS11500	COG0756	dUTP diphosphatase activity
C3Z10_RS11580	COG3655	Transcriptional regulator
C3Z10_RS11670	COG3655	Transcriptional regulator
C3Z10_RS11675	COG3655	Transcriptional regulator
C3Z10_RS11760	COG0776	regulation of translation
C3Z10_RS11915	COG0741	lytic transglycosylase activity
C3Z10_RS11915	COG0739	heme binding
C3Z10_RS11915	COG1196	nuclear chromosome segregation
C3Z10_RS11935	COG5434	Belongs to the glycosyl hydrolase 28 family
C3Z10_RS11940	COG3409	Peptidoglycan-binding domain 1 protein
C3Z10_RS11940	COG5632	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS11965	COG0457	Tetratricopeptide repeat
C3Z10_RS11970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C3Z10_RS12010	COG5444	nuclease activity
C3Z10_RS12015	COG1525	nuclease
C3Z10_RS12035	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C3Z10_RS12040	COG1199	ATP-dependent helicase activity
C3Z10_RS12055	COG0116	Belongs to the methyltransferase superfamily
C3Z10_RS12080	COG3359	exonuclease
C3Z10_RS12085	COG1205	dead DEAH box helicase
C3Z10_RS12085	COG1111	helicase
C3Z10_RS12090	COG2190	(PTS) system
C3Z10_RS12095	COG0071	Belongs to the small heat shock protein (HSP20) family
C3Z10_RS12135	COG4499	WXG100 protein secretion system (Wss), protein YukC
C3Z10_RS12135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3Z10_RS12145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C3Z10_RS12150	COG3935	DnaD domain protein
C3Z10_RS12160	COG0436	Aminotransferase
C3Z10_RS12165	COG5353	protein conserved in bacteria
C3Z10_RS12175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C3Z10_RS12175	COG1199	ATP-dependent helicase activity
C3Z10_RS12205	COG0438	transferase activity, transferring glycosyl groups
C3Z10_RS12210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3Z10_RS12225	COG1694	Mazg nucleotide pyrophosphohydrolase
C3Z10_RS12230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3Z10_RS12235	COG2140	Oxalate decarboxylase
C3Z10_RS12245	COG4347	Protein of unknown function (DUF1405)
C3Z10_RS12250	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C3Z10_RS12250	COG2010	Cytochrome c
C3Z10_RS12255	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C3Z10_RS12260	COG0723	plastoquinol--plastocyanin reductase activity
C3Z10_RS12275	COG0457	Tetratricopeptide repeat
C3Z10_RS12285	COG0287	Prephenate dehydrogenase
C3Z10_RS12320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C3Z10_RS12325	COG4401	Chorismate mutase type I
C3Z10_RS12340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C3Z10_RS12345	COG0105	UTP biosynthetic process
C3Z10_RS12350	COG0142	geranyltranstransferase activity
C3Z10_RS12360	COG0142	geranyltranstransferase activity
C3Z10_RS12375	COG0776	regulation of translation
C3Z10_RS12380	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C3Z10_RS12420	COG0539	negative regulation of cytoplasmic translation
C3Z10_RS12430	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C3Z10_RS12435	COG2959	enzyme of heme biosynthesis
C3Z10_RS12440	COG3409	Peptidoglycan-binding domain 1 protein
C3Z10_RS12440	COG3773	Cell wall hydrolase
C3Z10_RS12445	COG2339	peptidase activity
C3Z10_RS12450	COG0492	ferredoxin-NADP+ reductase activity
C3Z10_RS12455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C3Z10_RS12460	COG4862	establishment of competence for transformation
C3Z10_RS12465	COG1408	metallophosphoesterase
C3Z10_RS12475	COG1388	LysM domain
C3Z10_RS12480	COG1266	CAAX protease self-immunity
C3Z10_RS12485	COG0514	ATP-dependent DNA helicase (RecQ)
C3Z10_RS12490	COG4955	Helix-turn-helix domain
C3Z10_RS12495	COG1141	Ferredoxin
C3Z10_RS12500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C3Z10_RS12505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3Z10_RS12515	COG1595	DNA-templated transcription, initiation
C3Z10_RS12520	COG5002	protein histidine kinase activity
C3Z10_RS12525	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS12530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3Z10_RS12535	COG1333	cytochrome c biogenesis protein
C3Z10_RS12540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS12545	COG1187	pseudouridine synthase activity
C3Z10_RS12550	COG0700	Nucleoside recognition
C3Z10_RS12555	COG2715	membrane protein required for spore maturation
C3Z10_RS12560	COG1686	Belongs to the peptidase S11 family
C3Z10_RS12585	COG1547	Domain of unknown function (DUF309)
C3Z10_RS12595	COG0456	acetyltransferase
C3Z10_RS12610	COG0307	riboflavin synthase, alpha
C3Z10_RS12615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3Z10_RS12615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3Z10_RS12625	COG0681	Belongs to the peptidase S26 family
C3Z10_RS12635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C3Z10_RS12640	COG4086	secreted protein
C3Z10_RS12645	COG0019	diaminopimelate decarboxylase activity
C3Z10_RS12650	COG0697	spore germination
C3Z10_RS12665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3Z10_RS12685	COG1191	sigma factor activity
C3Z10_RS12695	COG1366	Belongs to the anti-sigma-factor antagonist family
C3Z10_RS12700	COG1686	Belongs to the peptidase S11 family
C3Z10_RS12705	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C3Z10_RS12710	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C3Z10_RS12715	COG4974	Belongs to the 'phage' integrase family
C3Z10_RS12725	COG0735	belongs to the Fur family
C3Z10_RS12730	COG1300	Membrane
C3Z10_RS12745	COG0281	malic enzyme
C3Z10_RS12750	COG1757	Na H antiporter
C3Z10_RS12755	COG1027	Aspartate ammonia-lyase
C3Z10_RS12760	COG0252	asparaginase activity
C3Z10_RS12765	COG1396	sequence-specific DNA binding
C3Z10_RS12770	COG1379	DNA repair
C3Z10_RS12775	COG0494	nUDIX hydrolase
C3Z10_RS12785	COG0667	Aldo Keto reductase
C3Z10_RS12795	COG1073	alpha beta
C3Z10_RS12805	COG4918	Iron-sulphur cluster biosynthesis
C3Z10_RS12810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C3Z10_RS12810	COG0456	acetyltransferase
C3Z10_RS12815	COG2329	Antibiotic biosynthesis monooxygenase
C3Z10_RS12820	COG0456	acetyltransferase
C3Z10_RS12825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C3Z10_RS12840	COG0628	permease
C3Z10_RS12850	COG0346	lactoylglutathione lyase activity
C3Z10_RS12860	COG3048	D-serine ammonia-lyase activity
C3Z10_RS12865	COG0300	oxidoreductase activity
C3Z10_RS12870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3Z10_RS12875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3Z10_RS12880	COG1024	Enoyl-CoA hydratase
C3Z10_RS12885	COG3425	synthase
C3Z10_RS12890	COG2124	cytochrome p450
C3Z10_RS12895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS12895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS12895	COG3321	synthase
C3Z10_RS12895	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS12895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3Z10_RS12900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS12900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS12900	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS12900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3Z10_RS12900	COG3321	synthase
C3Z10_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS12905	COG3321	synthase
C3Z10_RS12905	COG0300	oxidoreductase activity
C3Z10_RS12905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS12905	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS12910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS12910	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS12910	COG3321	synthase
C3Z10_RS12910	COG0300	oxidoreductase activity
C3Z10_RS12910	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS12915	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS12915	COG3321	synthase
C3Z10_RS12915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS12915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3Z10_RS12915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS12920	COG3321	synthase
C3Z10_RS12920	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS12920	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS12920	COG0300	oxidoreductase activity
C3Z10_RS12920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS12925	COG3321	synthase
C3Z10_RS12925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3Z10_RS12925	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS12925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS12925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3Z10_RS12930	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS12935	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS12950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C3Z10_RS12950	COG2070	2-Nitropropane dioxygenase
C3Z10_RS12960	COG0250	Participates in transcription elongation, termination and antitermination
C3Z10_RS12980	COG0596	Alpha beta hydrolase
C3Z10_RS12995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C3Z10_RS13000	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C3Z10_RS13015	COG0706	membrane insertase activity
C3Z10_RS13020	COG2195	Cleaves the N-terminal amino acid of tripeptides
C3Z10_RS13025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C3Z10_RS13030	COG0346	lactoylglutathione lyase activity
C3Z10_RS13035	COG1376	ErfK ybiS ycfS ynhG family protein
C3Z10_RS13040	COG4129	membrane
C3Z10_RS13045	COG1126	abc transporter atp-binding protein
C3Z10_RS13050	COG0765	amino acid transport
C3Z10_RS13055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3Z10_RS13065	COG1597	lipid kinase activity
C3Z10_RS13070	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3Z10_RS13075	COG0022	dehydrogenase e1 component
C3Z10_RS13080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3Z10_RS13085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3Z10_RS13090	COG3426	butyrate kinase activity
C3Z10_RS13095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C3Z10_RS13100	COG0280	phosphate acetyltransferase
C3Z10_RS13105	COG3829	transcription factor binding
C3Z10_RS13105	COG3290	protein histidine kinase activity
C3Z10_RS13115	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C3Z10_RS13120	COG2079	MmgE PrpD family protein
C3Z10_RS13125	COG0372	Belongs to the citrate synthase family
C3Z10_RS13130	COG1960	acyl-CoA dehydrogenase activity
C3Z10_RS13135	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3Z10_RS13140	COG0183	Belongs to the thiolase family
C3Z10_RS13145	COG0584	glycerophosphoryl diester phosphodiesterase
C3Z10_RS13150	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS13175	COG1902	pentaerythritol trinitrate reductase activity
C3Z10_RS13190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3Z10_RS13195	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS13200	COG0750	zinc metalloprotease
C3Z10_RS13205	COG0497	DNA recombination
C3Z10_RS13215	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C3Z10_RS13225	COG0142	geranyltranstransferase activity
C3Z10_RS13235	COG1570	exodeoxyribonuclease VII activity
C3Z10_RS13250	COG1302	Protein conserved in bacteria
C3Z10_RS13255	COG0439	Biotin carboxylase
C3Z10_RS13260	COG0511	ligase activity, forming carbon-carbon bonds
C3Z10_RS13300	COG3854	ATPases associated with a variety of cellular activities
C3Z10_RS13315	COG0006	proline dipeptidase activity
C3Z10_RS13325	COG3872	metal-dependent enzyme
C3Z10_RS13335	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3Z10_RS13350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3Z10_RS13370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3Z10_RS13385	COG1396	sequence-specific DNA binding
C3Z10_RS13395	COG0681	Belongs to the peptidase S26 family
C3Z10_RS13420	COG4940	Competence protein ComGF
C3Z10_RS13430	COG4970	Tfp pilus assembly protein FimT
C3Z10_RS13435	COG4537	Required for transformation and DNA binding
C3Z10_RS13440	COG1459	type II secretion system
C3Z10_RS13445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C3Z10_RS13450	COG0598	Magnesium transport protein CorA
C3Z10_RS13455	COG1253	flavin adenine dinucleotide binding
C3Z10_RS13460	COG1366	Belongs to the anti-sigma-factor antagonist family
C3Z10_RS13470	COG1393	Belongs to the ArsC family
C3Z10_RS13480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3Z10_RS13490	COG0011	TIGRFAM Protein of
C3Z10_RS13500	COG2866	Carboxypeptidase
C3Z10_RS13505	COG1940	carbohydrate kinase activity
C3Z10_RS13510	COG4483	Protein conserved in bacteria
C3Z10_RS13515	COG1757	Na H antiporter
C3Z10_RS13525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C3Z10_RS13540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C3Z10_RS13545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C3Z10_RS13550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C3Z10_RS13555	COG0581	inorganic phosphate transmembrane transporter activity
C3Z10_RS13560	COG0573	inorganic phosphate transmembrane transporter activity
C3Z10_RS13565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C3Z10_RS13570	COG0768	penicillin binding
C3Z10_RS13575	COG0477	Major facilitator Superfamily
C3Z10_RS13580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3Z10_RS13585	COG2839	Protein conserved in bacteria
C3Z10_RS13590	COG5521	maltodextrose utilization protein MalA
C3Z10_RS13595	COG1388	LysM domain
C3Z10_RS13605	COG4709	membrane
C3Z10_RS13610	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C3Z10_RS13615	COG0735	belongs to the Fur family
C3Z10_RS13620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3Z10_RS13635	COG0513	Belongs to the DEAD box helicase family
C3Z10_RS13650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C3Z10_RS13655	COG2384	SAM-dependent methyltransferase
C3Z10_RS13660	COG2010	Cytochrome c
C3Z10_RS13665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C3Z10_RS13670	COG0358	DNA primase activity
C3Z10_RS13685	COG0517	IMP dehydrogenase activity
C3Z10_RS13690	COG0751	glycine-tRNA ligase activity
C3Z10_RS13710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C3Z10_RS13715	COG0295	cytidine deaminase activity
C3Z10_RS13720	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C3Z10_RS13730	COG1480	7TM receptor with intracellular HD hydrolase
C3Z10_RS13735	COG1702	phosphate starvation-inducible protein PhoH
C3Z10_RS13740	COG0561	phosphatase activity
C3Z10_RS13755	COG4864	UPF0365 protein
C3Z10_RS13760	COG1030	water channel activity
C3Z10_RS13765	COG1610	YqeY-like protein
C3Z10_RS13775	COG1283	sodium-dependent phosphate transmembrane transporter activity
C3Z10_RS13780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C3Z10_RS13785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C3Z10_RS13815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3Z10_RS13830	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS13845	COG1466	dna polymerase III delta subunit
C3Z10_RS13855	COG2333	competence protein COMEC
C3Z10_RS13855	COG0658	competence protein
C3Z10_RS13860	COG2131	deaminase
C3Z10_RS13865	COG1596	polysaccharide export
C3Z10_RS13865	COG1555	photosystem II stabilization
C3Z10_RS13870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3Z10_RS13875	COG2226	methyltransferase
C3Z10_RS13880	COG0799	negative regulation of ribosome biogenesis
C3Z10_RS13885	COG1713	HD superfamily hydrolase involved in NAD metabolism
C3Z10_RS13895	COG1534	Rna-binding protein
C3Z10_RS13900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C3Z10_RS13905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C3Z10_RS13910	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C3Z10_RS13920	COG2755	lipolytic protein G-D-S-L family
C3Z10_RS13930	COG0398	Pfam SNARE associated Golgi protein
C3Z10_RS13955	COG1794	racemase activity, acting on amino acids and derivatives
C3Z10_RS13965	COG0114	fumarate hydratase activity
C3Z10_RS13975	COG0656	L-ascorbic acid biosynthetic process
C3Z10_RS14005	COG0642	Histidine kinase
C3Z10_RS14005	COG5002	protein histidine kinase activity
C3Z10_RS14010	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS14015	COG2311	Membrane
C3Z10_RS14020	COG0454	-acetyltransferase
C3Z10_RS14025	COG0563	adenylate kinase activity
C3Z10_RS14035	COG2814	Major facilitator Superfamily
C3Z10_RS14040	COG0456	acetyltransferase
C3Z10_RS14045	COG2318	DinB family
C3Z10_RS14055	COG0561	phosphatase activity
C3Z10_RS14060	COG0561	phosphatase activity
C3Z10_RS14070	COG1482	cell wall glycoprotein biosynthetic process
C3Z10_RS14075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3Z10_RS14075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3Z10_RS14075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3Z10_RS14080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3Z10_RS14080	COG3711	transcriptional antiterminator
C3Z10_RS14090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C3Z10_RS14095	COG0583	DNA-binding transcription factor activity
C3Z10_RS14100	COG2814	Major facilitator Superfamily
C3Z10_RS14105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C3Z10_RS14105	COG2124	cytochrome p450
C3Z10_RS14110	COG1309	transcriptional regulator
C3Z10_RS14115	COG2226	methyltransferase
C3Z10_RS14130	COG2116	formate transmembrane transporter activity
C3Z10_RS14135	COG5609	conserved protein (DUF2294)
C3Z10_RS14140	COG3383	formate dehydrogenase (NAD+) activity
C3Z10_RS14145	COG2427	Protein of unknown function (DUF1641)
C3Z10_RS14155	COG0626	cystathionine gamma-synthase activity
C3Z10_RS14160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3Z10_RS14185	COG0768	penicillin binding
C3Z10_RS14200	COG0826	peptidase U32
C3Z10_RS14205	COG0826	peptidase U32
C3Z10_RS14210	COG4122	O-methyltransferase activity
C3Z10_RS14215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C3Z10_RS14230	COG4472	Bacterial protein of unknown function (DUF965)
C3Z10_RS14240	COG0628	permease
C3Z10_RS14245	COG1126	abc transporter atp-binding protein
C3Z10_RS14250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3Z10_RS14255	COG0765	amino acid transport
C3Z10_RS14260	COG0765	amino acid transport
C3Z10_RS14275	COG3881	PFAM PRC-barrel domain
C3Z10_RS14280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3Z10_RS14285	COG0457	Tetratricopeptide repeat
C3Z10_RS14295	COG1104	cysteine desulfurase activity
C3Z10_RS14300	COG1959	2 iron, 2 sulfur cluster binding
C3Z10_RS14305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C3Z10_RS14310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C3Z10_RS14330	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS14330	COG4991	sh3 domain protein
C3Z10_RS14330	COG3103	Sh3 type 3 domain protein
C3Z10_RS14340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3Z10_RS14350	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C3Z10_RS14350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C3Z10_RS14355	COG5416	Lipopolysaccharide assembly protein A domain
C3Z10_RS14360	COG0490	domain, Protein
C3Z10_RS14365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3Z10_RS14365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3Z10_RS14375	COG2244	polysaccharide biosynthetic process
C3Z10_RS14380	COG2323	membrane
C3Z10_RS14390	COG1862	Preprotein translocase
C3Z10_RS14435	COG1388	LysM domain
C3Z10_RS14445	COG0157	Belongs to the NadC ModD family
C3Z10_RS14450	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C3Z10_RS14455	COG1104	cysteine desulfurase activity
C3Z10_RS14460	COG1827	regulation of RNA biosynthetic process
C3Z10_RS14465	COG0077	Prephenate dehydratase
C3Z10_RS14480	COG3290	protein histidine kinase activity
C3Z10_RS14485	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C3Z10_RS14490	COG2868	ribosomal protein
C3Z10_RS14500	COG1994	Peptidase M50
C3Z10_RS14505	COG0739	heme binding
C3Z10_RS14510	COG2894	cell division
C3Z10_RS14520	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C3Z10_RS14530	COG1077	Cell shape determining protein MreB Mrl
C3Z10_RS14550	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C3Z10_RS14555	COG0285	dihydrofolate synthase activity
C3Z10_RS14560	COG0525	valine-tRNA ligase activity
C3Z10_RS14570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3Z10_RS14575	COG1388	LysM domain
C3Z10_RS14585	COG0113	porphobilinogen synthase activity
C3Z10_RS14590	COG1587	Uroporphyrinogen-III synthase
C3Z10_RS14600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3Z10_RS14620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C3Z10_RS14625	COG1067	ATP-dependent peptidase activity
C3Z10_RS14625	COG0470	DNA polymerase III
C3Z10_RS14640	COG1477	protein flavinylation
C3Z10_RS14640	COG0457	Tetratricopeptide repeat
C3Z10_RS14655	COG0473	3-isopropylmalate dehydrogenase activity
C3Z10_RS14670	COG0440	acetolactate synthase activity
C3Z10_RS14675	COG0028	Belongs to the TPP enzyme family
C3Z10_RS14705	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
C3Z10_RS14725	COG0622	Phosphoesterase
C3Z10_RS14730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C3Z10_RS14740	COG5401	PFAM Sporulation and spore germination
C3Z10_RS14750	COG1846	Transcriptional regulator
C3Z10_RS14755	COG2197	response regulator
C3Z10_RS14760	COG0824	Thioesterase
C3Z10_RS14765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C3Z10_RS14770	COG1053	succinate dehydrogenase
C3Z10_RS14775	COG2009	succinate dehydrogenase
C3Z10_RS14780	COG1719	4-vinyl reductase, 4VR
C3Z10_RS14785	COG0527	aspartate kinase activity
C3Z10_RS14800	COG3118	belongs to the thioredoxin family
C3Z10_RS14805	COG3534	alpha-L-arabinofuranosidase
C3Z10_RS14810	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C3Z10_RS14815	COG2086	electron transfer activity
C3Z10_RS14820	COG1024	Enoyl-CoA hydratase
C3Z10_RS14825	COG1309	transcriptional regulator
C3Z10_RS14830	COG0318	PFAM AMP-dependent synthetase and ligase
C3Z10_RS14840	COG3766	membrane
C3Z10_RS14850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C3Z10_RS14850	COG1796	DNA polymerase
C3Z10_RS14855	COG1286	toxin biosynthetic process
C3Z10_RS14870	COG0072	phenylalanine-tRNA ligase activity
C3Z10_RS14870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3Z10_RS14875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C3Z10_RS14880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3Z10_RS14890	COG3835	regulator
C3Z10_RS14895	COG0277	FAD linked oxidase domain protein
C3Z10_RS14900	COG0247	lactate metabolic process
C3Z10_RS14905	COG1966	Carbon starvation protein
C3Z10_RS14910	COG3534	alpha-L-arabinofuranosidase
C3Z10_RS14915	COG0395	ABC-type sugar transport system, permease component
C3Z10_RS14920	COG1175	transmembrane transport
C3Z10_RS14925	COG1653	transport
C3Z10_RS14935	COG0647	UMP catabolic process
C3Z10_RS14940	COG0235	Class ii aldolase
C3Z10_RS14945	COG1069	ribulokinase activity
C3Z10_RS14950	COG2160	L-arabinose isomerase activity
C3Z10_RS14955	COG3507	Belongs to the glycosyl hydrolase 43 family
C3Z10_RS14960	COG1363	Peptidase, m42
C3Z10_RS14970	COG3326	Membrane
C3Z10_RS14975	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C3Z10_RS14985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C3Z10_RS14990	COG1346	cytolysis
C3Z10_RS14995	COG1380	Effector of murein hydrolase LrgA
C3Z10_RS15000	COG3279	Response regulator of the LytR AlgR family
C3Z10_RS15005	COG3275	phosphorelay sensor kinase activity
C3Z10_RS15015	COG1011	Hydrolase
C3Z10_RS15030	COG0398	Pfam SNARE associated Golgi protein
C3Z10_RS15035	COG1484	DNA-dependent DNA replication
C3Z10_RS15040	COG3611	Membrane attachment protein
C3Z10_RS15055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3Z10_RS15060	COG1733	regulation of RNA biosynthetic process
C3Z10_RS15065	COG2814	Major facilitator Superfamily
C3Z10_RS15070	COG0656	L-ascorbic acid biosynthetic process
C3Z10_RS15075	COG0237	dephospho-CoA kinase activity
C3Z10_RS15080	COG1971	Probably functions as a manganese efflux pump
C3Z10_RS15085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C3Z10_RS15090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3Z10_RS15090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3Z10_RS15095	COG5002	protein histidine kinase activity
C3Z10_RS15100	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS15110	COG0538	isocitrate dehydrogenase activity
C3Z10_RS15115	COG0372	Belongs to the citrate synthase family
C3Z10_RS15135	COG0628	permease
C3Z10_RS15140	COG3030	protein affecting phage T7 exclusion by the F plasmid
C3Z10_RS15145	COG0469	pyruvate kinase activity
C3Z10_RS15165	COG0281	malic enzyme
C3Z10_RS15170	COG0587	DNA-directed DNA polymerase activity
C3Z10_RS15190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C3Z10_RS15200	COG4109	DRTGG domain
C3Z10_RS15210	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS15225	COG0521	Mo-molybdopterin cofactor biosynthetic process
C3Z10_RS15235	COG0827	DNA restriction-modification system
C3Z10_RS15240	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C3Z10_RS15245	COG3874	Sporulation protein YtfJ
C3Z10_RS15255	COG1714	RDD family
C3Z10_RS15260	COG0616	signal peptide processing
C3Z10_RS15265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C3Z10_RS15270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C3Z10_RS15275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3Z10_RS15290	COG1104	cysteine desulfurase activity
C3Z10_RS15295	COG1114	Component of the transport system for branched-chain amino acids
C3Z10_RS15305	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C3Z10_RS15310	COG1309	transcriptional regulator
C3Z10_RS15315	COG1956	GAF domain-containing protein
C3Z10_RS15320	COG2199	diguanylate cyclase activity
C3Z10_RS15320	COG2203	Gaf domain
C3Z10_RS15335	COG1012	belongs to the aldehyde dehydrogenase family
C3Z10_RS15340	COG4282	regulation of fungal-type cell wall biogenesis
C3Z10_RS15350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C3Z10_RS15350	COG1017	nitric oxide dioxygenase activity
C3Z10_RS15360	COG0693	protein deglycase activity
C3Z10_RS15375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C3Z10_RS15380	COG1378	Sugar-specific transcriptional regulator TrmB
C3Z10_RS15405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3Z10_RS15410	COG0454	-acetyltransferase
C3Z10_RS15415	COG0517	IMP dehydrogenase activity
C3Z10_RS15420	COG0123	including yeast histone deacetylase and acetoin utilization protein
C3Z10_RS15425	COG1360	Flagellar Motor Protein
C3Z10_RS15430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C3Z10_RS15435	COG1609	Transcriptional regulator
C3Z10_RS15440	COG1605	Chorismate mutase
C3Z10_RS15440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C3Z10_RS15445	COG3118	belongs to the thioredoxin family
C3Z10_RS15450	COG4980	gas vesicle protein
C3Z10_RS15455	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C3Z10_RS15465	COG1674	ftsk spoiiie
C3Z10_RS15470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3Z10_RS15480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS15490	COG1363	Peptidase, m42
C3Z10_RS15495	COG5584	Small secreted protein
C3Z10_RS15500	COG0281	malic enzyme
C3Z10_RS15505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3Z10_RS15520	COG0510	thiamine kinase activity
C3Z10_RS15525	COG1597	lipid kinase activity
C3Z10_RS15535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C3Z10_RS15540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3Z10_RS15545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3Z10_RS15550	COG2252	PERMEase
C3Z10_RS15555	COG4473	ABC transporter
C3Z10_RS15560	COG1131	(ABC) transporter
C3Z10_RS15565	COG1349	DNA-binding transcription factor activity
C3Z10_RS15570	COG1187	pseudouridine synthase activity
C3Z10_RS15575	COG2244	polysaccharide biosynthetic process
C3Z10_RS15580	COG2081	HI0933 family
C3Z10_RS15585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3Z10_RS15595	COG1609	Transcriptional regulator
C3Z10_RS15600	COG1653	transport
C3Z10_RS15605	COG1175	transmembrane transport
C3Z10_RS15610	COG0395	ABC-type sugar transport system, permease component
C3Z10_RS15615	COG1486	melibiose metabolic process
C3Z10_RS15625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3Z10_RS15640	COG2202	Pas domain
C3Z10_RS15640	COG1366	Belongs to the anti-sigma-factor antagonist family
C3Z10_RS15645	COG2814	Major facilitator Superfamily
C3Z10_RS15650	COG5522	Integral membrane protein (intg_mem_TP0381)
C3Z10_RS15655	COG0577	efflux transmembrane transporter activity
C3Z10_RS15660	COG1136	(ABC) transporter
C3Z10_RS15665	COG2205	protein histidine kinase activity
C3Z10_RS15670	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS15675	COG0577	efflux transmembrane transporter activity
C3Z10_RS15680	COG1136	(ABC) transporter
C3Z10_RS15700	COG1131	(ABC) transporter
C3Z10_RS15705	COG1725	Transcriptional regulator
C3Z10_RS15715	COG0640	Transcriptional regulator
C3Z10_RS15720	COG0477	Major facilitator Superfamily
C3Z10_RS15725	COG1242	4 iron, 4 sulfur cluster binding
C3Z10_RS15730	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C3Z10_RS15740	COG0584	glycerophosphoryl diester phosphodiesterase
C3Z10_RS15750	COG2267	carboxylic ester hydrolase activity
C3Z10_RS15755	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C3Z10_RS15760	COG1113	amino acid transport
C3Z10_RS15765	COG0367	asparagine synthase
C3Z10_RS15785	COG1506	peptidase
C3Z10_RS15790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3Z10_RS15795	COG1116	anion transmembrane transporter activity
C3Z10_RS15800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3Z10_RS15805	COG0494	nUDIX hydrolase
C3Z10_RS15810	COG4824	toxin secretion phage lysis holin
C3Z10_RS15815	COG0783	Belongs to the Dps family
C3Z10_RS15840	COG0288	reversible hydration of carbon dioxide
C3Z10_RS15850	COG1271	oxidase subunit
C3Z10_RS15855	COG1294	oxidase, subunit
C3Z10_RS15865	COG4948	Mandelate Racemase Muconate Lactonizing
C3Z10_RS15875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C3Z10_RS15880	COG0596	Alpha beta hydrolase
C3Z10_RS15890	COG1169	isochorismate synthase
C3Z10_RS15895	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C3Z10_RS15900	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C3Z10_RS16025	COG3859	Proton-coupled thiamine transporter YuaJ
C3Z10_RS16070	COG2433	Pfam Transposase IS66
C3Z10_RS16075	COG0739	heme binding
C3Z10_RS16075	COG0741	lytic transglycosylase activity
C3Z10_RS16075	COG1196	nuclear chromosome segregation
C3Z10_RS16110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C3Z10_RS16215	COG1585	Membrane protein implicated in regulation of membrane protease activity
C3Z10_RS16220	COG2318	DinB family
C3Z10_RS16230	COG1454	alcohol dehydrogenase
C3Z10_RS16235	COG1012	belongs to the aldehyde dehydrogenase family
C3Z10_RS16240	COG1510	regulation of RNA biosynthetic process
C3Z10_RS16250	COG0569	domain protein
C3Z10_RS16255	COG1705	Flagellar rod assembly protein muramidase FlgJ
C3Z10_RS16260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C3Z10_RS16260	COG1017	nitric oxide dioxygenase activity
C3Z10_RS16310	COG5632	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS16410	COG0740	serine-type endopeptidase activity
C3Z10_RS16500	COG0582	viral genome integration into host DNA
C3Z10_RS16510	COG0628	permease
C3Z10_RS16515	COG0673	inositol 2-dehydrogenase activity
C3Z10_RS16520	COG0693	protein deglycase activity
C3Z10_RS16525	COG0840	transmembrane signaling receptor activity
C3Z10_RS16530	COG0840	transmembrane signaling receptor activity
C3Z10_RS16535	COG0840	transmembrane signaling receptor activity
C3Z10_RS16540	COG0840	transmembrane signaling receptor activity
C3Z10_RS16555	COG2070	2-Nitropropane dioxygenase
C3Z10_RS16560	COG0432	Pfam Uncharacterised protein family UPF0047
C3Z10_RS16565	COG0366	Alpha amylase catalytic
C3Z10_RS16570	COG1253	flavin adenine dinucleotide binding
C3Z10_RS16575	COG2738	Putative neutral zinc metallopeptidase
C3Z10_RS16590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3Z10_RS16620	COG1335	isochorismatase
C3Z10_RS16625	COG1979	alcohol dehydrogenase
C3Z10_RS16630	COG1979	alcohol dehydrogenase
C3Z10_RS16635	COG2155	Conserved Protein
C3Z10_RS16640	COG1098	S1 RNA binding domain
C3Z10_RS16645	COG0436	Aminotransferase
C3Z10_RS16650	COG1522	sequence-specific DNA binding
C3Z10_RS16655	COG2267	carboxylic ester hydrolase activity
C3Z10_RS16665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C3Z10_RS16670	COG2205	protein histidine kinase activity
C3Z10_RS16680	COG5018	Exonuclease
C3Z10_RS16685	COG2814	Major facilitator Superfamily
C3Z10_RS16690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3Z10_RS16695	COG3011	Protein conserved in bacteria
C3Z10_RS16705	COG3290	protein histidine kinase activity
C3Z10_RS16710	COG4565	transcriptional regulatory protein
C3Z10_RS16715	COG1744	ABC transporter substrate-binding protein PnrA-like
C3Z10_RS16720	COG3845	ABC transporter
C3Z10_RS16725	COG4603	Belongs to the binding-protein-dependent transport system permease family
C3Z10_RS16730	COG1079	Belongs to the binding-protein-dependent transport system permease family
C3Z10_RS16740	COG2111	Na H antiporter
C3Z10_RS16740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3Z10_RS16745	COG2111	Na H antiporter
C3Z10_RS16750	COG1006	Multisubunit Na H antiporter MnhC subunit
C3Z10_RS16755	COG0651	ATP synthesis coupled electron transport
C3Z10_RS16760	COG1863	multisubunit Na H antiporter MnhE subunit
C3Z10_RS16765	COG2212	antiporter activity
C3Z10_RS16770	COG1320	monovalent cation:proton antiporter activity
C3Z10_RS16775	COG2050	protein possibly involved in aromatic compounds catabolism
C3Z10_RS16780	COG2197	response regulator
C3Z10_RS16795	COG0142	geranyltranstransferase activity
C3Z10_RS16815	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C3Z10_RS16820	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C3Z10_RS16825	COG1335	isochorismatase
C3Z10_RS16830	COG5506	Protein of unknown function (DUF1694)
C3Z10_RS16845	COG0628	permease
C3Z10_RS16855	COG1418	mRNA catabolic process
C3Z10_RS16860	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS16870	COG1511	domain protein
C3Z10_RS16875	COG1674	ftsk spoiiie
C3Z10_RS16875	COG0433	COG0433 Predicted ATPase
C3Z10_RS16880	COG4499	WXG100 protein secretion system (Wss), protein YukC
C3Z10_RS16885	COG5417	Belongs to the EsaB family
C3Z10_RS16890	COG4842	Belongs to the WXG100 family
C3Z10_RS16895	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C3Z10_RS16895	COG2508	Transcriptional regulator
C3Z10_RS16900	COG0686	Belongs to the AlaDH PNT family
C3Z10_RS16905	COG5634	Uncharacterized conserved protein (DUF2278)
C3Z10_RS16910	COG3251	PFAM MbtH domain protein
C3Z10_RS16915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3Z10_RS16920	COG3433	isochorismatase activity
C3Z10_RS16920	COG1535	isochorismatase
C3Z10_RS16925	COG1021	2,3-dihydroxybenzoate-AMP ligase
C3Z10_RS16930	COG1169	isochorismate synthase
C3Z10_RS16935	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS16940	COG2819	hydrolase of the alpha beta superfamily
C3Z10_RS16945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C3Z10_RS16950	COG1268	BioY protein
C3Z10_RS16955	COG2056	Na+-H+ antiporter family
C3Z10_RS16965	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C3Z10_RS16970	COG3584	3D domain protein
C3Z10_RS16985	COG1252	NADH dehydrogenase
C3Z10_RS17015	COG1131	(ABC) transporter
C3Z10_RS17035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3Z10_RS17040	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C3Z10_RS17055	COG0316	Belongs to the HesB IscA family
C3Z10_RS17065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3Z10_RS17075	COG1252	NADH dehydrogenase
C3Z10_RS17080	COG4837	Protein of unknown function (DUF1462)
C3Z10_RS17085	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C3Z10_RS17090	COG4946	Tricorn protease homolog
C3Z10_RS17090	COG0823	Involved in the tonB-independent uptake of proteins
C3Z10_RS17090	COG1506	peptidase
C3Z10_RS17100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C3Z10_RS17105	COG0460	homoserine dehydrogenase
C3Z10_RS17110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3Z10_RS17115	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C3Z10_RS17120	COG0647	UMP catabolic process
C3Z10_RS17125	COG2445	Protein of unknown function DUF86
C3Z10_RS17130	COG4470	Protein conserved in bacteria
C3Z10_RS17145	COG0739	heme binding
C3Z10_RS17155	COG0737	Belongs to the 5'-nucleotidase family
C3Z10_RS17160	COG0730	response to heat
C3Z10_RS17165	COG1801	Protein of unknown function DUF72
C3Z10_RS17180	COG2508	Transcriptional regulator
C3Z10_RS17195	COG2814	Major facilitator Superfamily
C3Z10_RS17200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C3Z10_RS17205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3Z10_RS17210	COG2356	endonuclease I
C3Z10_RS17215	COG3842	ATPase activity
C3Z10_RS17220	COG2188	Transcriptional regulator
C3Z10_RS17225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3Z10_RS17230	COG0395	ABC-type sugar transport system, permease component
C3Z10_RS17235	COG1175	transmembrane transport
C3Z10_RS17240	COG1653	transport
C3Z10_RS17245	COG2222	sugar isomerase
C3Z10_RS17250	COG0789	Transcriptional regulator
C3Z10_RS17275	COG0322	excinuclease ABC activity
C3Z10_RS17280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3Z10_RS17285	COG2226	methyltransferase
C3Z10_RS17295	COG3409	Peptidoglycan-binding domain 1 protein
C3Z10_RS17305	COG0719	Fe-S assembly protein
C3Z10_RS17310	COG0822	iron-sulfur transferase activity
C3Z10_RS17315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C3Z10_RS17320	COG0719	Fe-S assembly protein
C3Z10_RS17325	COG0396	ATPase activity
C3Z10_RS17335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C3Z10_RS17340	COG1464	Belongs to the NlpA lipoprotein family
C3Z10_RS17345	COG2011	ABC-type metal ion transport system permease component
C3Z10_RS17350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C3Z10_RS17360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3Z10_RS17365	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C3Z10_RS17380	COG1393	Belongs to the ArsC family
C3Z10_RS17385	COG1960	acyl-CoA dehydrogenase activity
C3Z10_RS17390	COG0183	Belongs to the thiolase family
C3Z10_RS17395	COG1024	Enoyl-CoA hydratase
C3Z10_RS17395	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3Z10_RS17410	COG0477	Major facilitator Superfamily
C3Z10_RS17420	COG5577	PFAM Coat F domain
C3Z10_RS17425	COG1846	Transcriptional regulator
C3Z10_RS17430	COG0477	Major facilitator Superfamily
C3Z10_RS17435	COG0583	DNA-binding transcription factor activity
C3Z10_RS17455	COG1120	ATPase activity
C3Z10_RS17470	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS17475	COG0783	Belongs to the Dps family
C3Z10_RS17480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3Z10_RS17485	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS17490	COG2205	protein histidine kinase activity
C3Z10_RS17490	COG2770	Histidine kinase
C3Z10_RS17500	COG1309	transcriptional regulator
C3Z10_RS17505	COG0114	fumarate hydratase activity
C3Z10_RS17515	COG0697	spore germination
C3Z10_RS17520	COG0814	amino acid
C3Z10_RS17530	COG2197	response regulator
C3Z10_RS17535	COG4585	Histidine kinase
C3Z10_RS17540	COG4758	membrane
C3Z10_RS17545	COG3595	metallopeptidase activity
C3Z10_RS17550	COG1842	Phage shock protein A
C3Z10_RS17555	COG4758	membrane
C3Z10_RS17560	COG2814	Major facilitator Superfamily
C3Z10_RS17565	COG2096	Adenosyltransferase
C3Z10_RS17570	COG1120	ATPase activity
C3Z10_RS17575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3Z10_RS17580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3Z10_RS17585	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS17590	COG3386	PFAM SMP-30 Gluconolaconase
C3Z10_RS17595	COG2205	protein histidine kinase activity
C3Z10_RS17600	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS17610	COG1191	sigma factor activity
C3Z10_RS17620	COG2140	Oxalate decarboxylase
C3Z10_RS17630	COG1120	ATPase activity
C3Z10_RS17635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3Z10_RS17640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3Z10_RS17645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3Z10_RS17650	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C3Z10_RS17655	COG0531	amino acid
C3Z10_RS17670	COG1988	membrane-bound metal-dependent
C3Z10_RS17675	COG1368	sulfuric ester hydrolase activity
C3Z10_RS17680	COG1910	domain protein
C3Z10_RS17685	COG0725	ABC transporter, periplasmic molybdate-binding protein
C3Z10_RS17690	COG4149	molybdate abc transporter
C3Z10_RS17695	COG2197	response regulator
C3Z10_RS17700	COG3850	Histidine kinase
C3Z10_RS17705	COG1131	(ABC) transporter
C3Z10_RS17715	COG0842	Transport permease protein
C3Z10_RS17720	COG0656	L-ascorbic acid biosynthetic process
C3Z10_RS17745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C3Z10_RS17750	COG3973	AAA domain
C3Z10_RS17755	COG2860	membrane
C3Z10_RS17765	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C3Z10_RS17770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3Z10_RS17775	COG2217	Heavy metal translocating P-type atpase
C3Z10_RS17780	COG2217	Heavy metal translocating P-type atpase
C3Z10_RS17785	COG2608	mercury ion transmembrane transporter activity
C3Z10_RS17790	COG1937	Protein conserved in bacteria
C3Z10_RS17795	COG0673	inositol 2-dehydrogenase activity
C3Z10_RS17815	COG2814	Major facilitator Superfamily
C3Z10_RS17830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3Z10_RS17835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C3Z10_RS17840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3Z10_RS17845	COG1126	abc transporter atp-binding protein
C3Z10_RS17850	COG0765	amino acid transport
C3Z10_RS17855	COG0765	amino acid transport
C3Z10_RS17860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3Z10_RS17865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3Z10_RS17875	COG0583	DNA-binding transcription factor activity
C3Z10_RS17880	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS17885	COG2732	(Barnase) inhibitor
C3Z10_RS17890	COG2732	(Barnase) inhibitor
C3Z10_RS17905	COG0557	exoribonuclease II activity
C3Z10_RS17910	COG1647	Serine aminopeptidase, S33
C3Z10_RS17915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C3Z10_RS17920	COG1476	TRANSCRIPTIONal
C3Z10_RS17925	COG1396	sequence-specific DNA binding
C3Z10_RS17930	COG1396	sequence-specific DNA binding
C3Z10_RS17935	COG1733	regulation of RNA biosynthetic process
C3Z10_RS17960	COG1131	(ABC) transporter
C3Z10_RS17965	COG1174	glycine betaine transport
C3Z10_RS17970	COG1732	Glycine betaine
C3Z10_RS17975	COG1174	glycine betaine transport
C3Z10_RS17980	COG1125	glycine betaine transport
C3Z10_RS17980	COG0517	IMP dehydrogenase activity
C3Z10_RS17985	COG1510	regulation of RNA biosynthetic process
C3Z10_RS17990	COG1174	glycine betaine transport
C3Z10_RS17995	COG1732	Glycine betaine
C3Z10_RS18000	COG1174	glycine betaine transport
C3Z10_RS18005	COG1125	glycine betaine transport
C3Z10_RS18005	COG0517	IMP dehydrogenase activity
C3Z10_RS18010	COG1510	regulation of RNA biosynthetic process
C3Z10_RS18015	COG2095	MarC family integral membrane protein
C3Z10_RS18020	COG3064	Membrane
C3Z10_RS18025	COG4640	response to antibiotic
C3Z10_RS18030	COG0456	acetyltransferase
C3Z10_RS18045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3Z10_RS18065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3Z10_RS18070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C3Z10_RS18080	COG2234	aminopeptidase activity
C3Z10_RS18100	COG0126	phosphoglycerate kinase activity
C3Z10_RS18110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3Z10_RS18115	COG2390	Transcriptional regulator
C3Z10_RS18120	COG2814	Major facilitator Superfamily
C3Z10_RS18125	COG1609	Transcriptional regulator
C3Z10_RS18130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3Z10_RS18140	COG0583	DNA-binding transcription factor activity
C3Z10_RS18145	COG0697	spore germination
C3Z10_RS18150	COG1113	amino acid transport
C3Z10_RS18160	COG1609	Transcriptional regulator
C3Z10_RS18170	COG0561	phosphatase activity
C3Z10_RS18175	COG1737	Transcriptional regulator
C3Z10_RS18180	COG1070	Carbohydrate kinase
C3Z10_RS18205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3Z10_RS18210	COG2186	Transcriptional regulator
C3Z10_RS18215	COG1620	l-lactate permease
C3Z10_RS18220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C3Z10_RS18230	COG5039	Polysaccharide pyruvyl transferase
C3Z10_RS18235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C3Z10_RS18240	COG0110	maltose O-acetyltransferase activity
C3Z10_RS18245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C3Z10_RS18250	COG2244	polysaccharide biosynthetic process
C3Z10_RS18255	COG1216	Glycosyl transferase, family 2
C3Z10_RS18260	COG5039	Polysaccharide pyruvyl transferase
C3Z10_RS18265	COG1216	Glycosyl transferase, family 2
C3Z10_RS18275	COG0438	transferase activity, transferring glycosyl groups
C3Z10_RS18280	COG1215	transferase activity, transferring glycosyl groups
C3Z10_RS18285	COG0438	transferase activity, transferring glycosyl groups
C3Z10_RS18290	COG1086	Polysaccharide biosynthesis protein
C3Z10_RS18295	COG0489	protein tyrosine kinase activity
C3Z10_RS18300	COG3944	biosynthesis protein
C3Z10_RS18305	COG1396	sequence-specific DNA binding
C3Z10_RS18310	COG2272	Belongs to the type-B carboxylesterase lipase family
C3Z10_RS18315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C3Z10_RS18320	COG2364	Membrane
C3Z10_RS18325	COG0456	acetyltransferase
C3Z10_RS18330	COG3479	Phenolic acid decarboxylase
C3Z10_RS18395	COG2211	Major facilitator Superfamily
C3Z10_RS18400	COG1609	Transcriptional regulator
C3Z10_RS18410	COG0583	DNA-binding transcription factor activity
C3Z10_RS18415	COG2828	Protein conserved in bacteria
C3Z10_RS18420	COG0477	Major facilitator Superfamily
C3Z10_RS18420	COG2814	Major facilitator Superfamily
C3Z10_RS18425	COG1611	Belongs to the LOG family
C3Z10_RS18430	COG1694	Mazg nucleotide pyrophosphohydrolase
C3Z10_RS18435	COG0659	secondary active sulfate transmembrane transporter activity
C3Z10_RS18440	COG0288	reversible hydration of carbon dioxide
C3Z10_RS18450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3Z10_RS18455	COG4290	ribonuclease
C3Z10_RS18460	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C3Z10_RS18465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3Z10_RS18475	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C3Z10_RS18485	COG1051	belongs to the nudix hydrolase family
C3Z10_RS18490	COG0492	ferredoxin-NADP+ reductase activity
C3Z10_RS18495	COG3883	PFAM NLP P60 protein
C3Z10_RS18495	COG0791	NLP P60 protein
C3Z10_RS18500	COG0457	Tetratricopeptide repeat
C3Z10_RS18505	COG5002	protein histidine kinase activity
C3Z10_RS18510	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS18520	COG1132	(ABC) transporter
C3Z10_RS18525	COG0140	phosphoribosyl-ATP diphosphatase activity
C3Z10_RS18525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C3Z10_RS18550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C3Z10_RS18565	COG4990	cell redox homeostasis
C3Z10_RS18570	COG0110	maltose O-acetyltransferase activity
C3Z10_RS18590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C3Z10_RS18600	COG2188	Transcriptional regulator
C3Z10_RS18605	COG1309	transcriptional regulator
C3Z10_RS18610	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C3Z10_RS18615	COG1950	PFAM Membrane protein of
C3Z10_RS18620	COG1983	PspC domain protein
C3Z10_RS18625	COG3595	metallopeptidase activity
C3Z10_RS18640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C3Z10_RS18650	COG4897	Protein conserved in bacteria
C3Z10_RS18655	COG0574	Belongs to the PEP-utilizing enzyme family
C3Z10_RS18655	COG3848	Pyruvate phosphate dikinase
C3Z10_RS18660	COG1309	transcriptional regulator
C3Z10_RS18665	COG2814	Major facilitator Superfamily
C3Z10_RS18710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3Z10_RS18720	COG3409	Peptidoglycan-binding domain 1 protein
C3Z10_RS18720	COG0793	Belongs to the peptidase S41A family
C3Z10_RS18725	COG3420	alginic acid biosynthetic process
C3Z10_RS18730	COG2177	Part of the ABC transporter FtsEX involved in
C3Z10_RS18735	COG2884	Cell division ATP-binding protein ftsE
C3Z10_RS18740	COG2010	Cytochrome c
C3Z10_RS18745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3Z10_RS18760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C3Z10_RS18775	COG1516	flagellar protein fliS
C3Z10_RS18780	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C3Z10_RS18785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3Z10_RS18805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3Z10_RS18810	COG1256	bacterial-type flagellum assembly
C3Z10_RS18810	COG4786	Flagellar basal body rod
C3Z10_RS18815	COG3418	PFAM FlgN family protein
C3Z10_RS18820	COG2747	anti-sigma28 factor FlgM
C3Z10_RS18830	COG1040	competence protein
C3Z10_RS18840	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C3Z10_RS18845	COG1307	EDD domain protein, DegV family
C3Z10_RS18850	COG2197	response regulator
C3Z10_RS18855	COG4585	Histidine kinase
C3Z10_RS18860	COG1739	Uncharacterized protein family UPF0029
C3Z10_RS18865	COG1316	TRANSCRIPTIONal
C3Z10_RS18870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C3Z10_RS18875	COG0438	transferase activity, transferring glycosyl groups
C3Z10_RS18880	COG1215	transferase activity, transferring glycosyl groups
C3Z10_RS18885	COG3206	protein involved in exopolysaccharide biosynthesis
C3Z10_RS18890	COG3307	-O-antigen
C3Z10_RS18895	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C3Z10_RS18900	COG0438	transferase activity, transferring glycosyl groups
C3Z10_RS18900	COG0297	glycogen (starch) synthase activity
C3Z10_RS18905	COG2244	polysaccharide biosynthetic process
C3Z10_RS18915	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3Z10_RS18915	COG2247	cell wall binding repeat
C3Z10_RS18920	COG2247	cell wall binding repeat
C3Z10_RS18920	COG2385	sporulation resulting in formation of a cellular spore
C3Z10_RS18930	COG1316	TRANSCRIPTIONal
C3Z10_RS18935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3Z10_RS18940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C3Z10_RS18945	COG1134	teichoic acid transport
C3Z10_RS18950	COG1682	transport, permease protein
C3Z10_RS18955	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C3Z10_RS18965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C3Z10_RS18970	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C3Z10_RS18975	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C3Z10_RS18980	COG4193	domain, Protein
C3Z10_RS18985	COG1482	cell wall glycoprotein biosynthetic process
C3Z10_RS18990	COG0697	spore germination
C3Z10_RS18995	COG0814	amino acid
C3Z10_RS19005	COG1215	transferase activity, transferring glycosyl groups
C3Z10_RS19010	COG2814	Major facilitator Superfamily
C3Z10_RS19015	COG1316	TRANSCRIPTIONal
C3Z10_RS19020	COG0561	phosphatase activity
C3Z10_RS19025	COG2433	Pfam Transposase IS66
C3Z10_RS19030	COG0791	NLP P60 protein
C3Z10_RS19040	COG2843	Capsule synthesis protein
C3Z10_RS19050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C3Z10_RS19060	COG0697	spore germination
C3Z10_RS19065	COG0814	amino acid
C3Z10_RS19075	COG1609	Transcriptional regulator
C3Z10_RS19080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3Z10_RS19090	COG1129	ABC transporter
C3Z10_RS19095	COG1172	Belongs to the binding-protein-dependent transport system permease family
C3Z10_RS19100	COG1879	ABC-type sugar transport system periplasmic component
C3Z10_RS19105	COG3103	Sh3 type 3 domain protein
C3Z10_RS19110	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3Z10_RS19115	COG3527	Alpha-acetolactate decarboxylase
C3Z10_RS19120	COG0028	Belongs to the TPP enzyme family
C3Z10_RS19125	COG0583	DNA-binding transcription factor activity
C3Z10_RS19130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3Z10_RS19145	COG5337	Spore coat protein CotH
C3Z10_RS19155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3Z10_RS19165	COG0405	Gamma-glutamyltransferase
C3Z10_RS19170	COG1522	sequence-specific DNA binding
C3Z10_RS19175	COG2059	Chromate
C3Z10_RS19180	COG2059	Chromate
C3Z10_RS19235	COG5444	nuclease activity
C3Z10_RS19250	COG3878	Protein conserved in bacteria
C3Z10_RS19255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C3Z10_RS19260	COG4464	protein tyrosine phosphatase activity
C3Z10_RS19265	COG0489	protein tyrosine kinase activity
C3Z10_RS19270	COG3944	biosynthesis protein
C3Z10_RS19285	COG4715	Zinc finger, swim domain protein
C3Z10_RS19290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3Z10_RS19295	COG0561	phosphatase activity
C3Z10_RS19300	COG1349	DNA-binding transcription factor activity
C3Z10_RS19305	COG0629	single-stranded DNA binding
C3Z10_RS19330	COG0457	Tetratricopeptide repeat
C3Z10_RS19335	COG4786	Flagellar basal body rod
C3Z10_RS19340	COG4786	Flagellar basal body rod
C3Z10_RS19345	COG1077	Cell shape determining protein MreB Mrl
C3Z10_RS19350	COG1609	Transcriptional regulator
C3Z10_RS19355	COG1846	Transcriptional regulator
C3Z10_RS19360	COG2814	Major facilitator Superfamily
C3Z10_RS19365	COG1953	Uracil, thiamine, allantoin
C3Z10_RS19370	COG0477	Major facilitator Superfamily
C3Z10_RS19375	COG1335	isochorismatase
C3Z10_RS19380	COG0004	ammonium transporteR
C3Z10_RS19385	COG0347	Belongs to the P(II) protein family
C3Z10_RS19390	COG0772	Belongs to the SEDS family
C3Z10_RS19395	COG0671	phosphoesterase, PA-phosphatase related
C3Z10_RS19405	COG0739	heme binding
C3Z10_RS19410	COG1247	-acetyltransferase
C3Z10_RS19425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3Z10_RS19435	COG0726	polysaccharide deacetylase
C3Z10_RS19445	COG1959	2 iron, 2 sulfur cluster binding
C3Z10_RS19460	COG0831	urea catabolic process
C3Z10_RS19470	COG1994	Peptidase M50
C3Z10_RS19475	COG0457	Tetratricopeptide repeat
C3Z10_RS19485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C3Z10_RS19490	COG2304	oxidoreductase activity
C3Z10_RS19495	COG2304	oxidoreductase activity
C3Z10_RS19505	COG2385	sporulation resulting in formation of a cellular spore
C3Z10_RS19510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C3Z10_RS19520	COG4836	Membrane
C3Z10_RS19590	COG0698	ribose 5-phosphate isomerase
C3Z10_RS19595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C3Z10_RS19605	COG0009	L-threonylcarbamoyladenylate synthase
C3Z10_RS19610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C3Z10_RS19630	COG2890	protein-(glutamine-N5) methyltransferase activity
C3Z10_RS19635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C3Z10_RS19640	COG0346	lactoylglutathione lyase activity
C3Z10_RS19645	COG0789	Transcriptional regulator
C3Z10_RS19650	COG0679	Auxin Efflux Carrier
C3Z10_RS19655	COG0281	malic enzyme
C3Z10_RS19670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C3Z10_RS19675	COG1494	fructose-1,6-bisphosphatase
C3Z10_RS19680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C3Z10_RS19695	COG0191	fructose-bisphosphate aldolase activity
C3Z10_RS19700	COG2204	response regulator
C3Z10_RS19705	COG4821	SIS domain
C3Z10_RS19720	COG0247	lactate metabolic process
C3Z10_RS19720	COG2181	nitrate reductase activity
C3Z10_RS19725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3Z10_RS19740	COG1132	(ABC) transporter
C3Z10_RS19745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3Z10_RS19755	COG2181	nitrate reductase activity
C3Z10_RS19760	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C3Z10_RS19765	COG1140	nitrate reductase beta subunit
C3Z10_RS19770	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C3Z10_RS19775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C3Z10_RS19785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C3Z10_RS19790	COG2223	nitrite transmembrane transporter activity
C3Z10_RS19800	COG4506	Protein conserved in bacteria
C3Z10_RS19815	COG3391	amine dehydrogenase activity
C3Z10_RS19825	COG0457	Tetratricopeptide repeat
C3Z10_RS19870	COG0010	Belongs to the arginase family
C3Z10_RS19875	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C3Z10_RS19880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3Z10_RS19895	COG1994	Peptidase M50
C3Z10_RS19900	COG1942	4-Oxalocrotonate Tautomerase
C3Z10_RS19905	COG1846	Transcriptional regulator
C3Z10_RS19915	COG0531	amino acid
C3Z10_RS19920	COG3465	dGTPase activity
C3Z10_RS19925	COG1078	dGTPase activity
C3Z10_RS19940	COG1695	Transcriptional regulator
C3Z10_RS19950	COG1131	(ABC) transporter
C3Z10_RS19955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C3Z10_RS19985	COG0583	DNA-binding transcription factor activity
C3Z10_RS19990	COG2855	membrane
C3Z10_RS19995	COG0280	phosphate acetyltransferase
C3Z10_RS20005	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS20010	COG0436	Aminotransferase
C3Z10_RS20040	COG2814	Major facilitator Superfamily
C3Z10_RS20045	COG2814	Major facilitator Superfamily
C3Z10_RS20050	COG0833	amino acid
C3Z10_RS20055	COG4187	Peptidase family M20/M25/M40
C3Z10_RS20060	COG1012	belongs to the aldehyde dehydrogenase family
C3Z10_RS20065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C3Z10_RS20075	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C3Z10_RS20080	COG1091	dTDP-4-dehydrorhamnose reductase activity
C3Z10_RS20085	COG1088	dTDP-glucose 4,6-dehydratase activity
C3Z10_RS20090	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C3Z10_RS20095	COG3980	spore coat polysaccharide biosynthesis protein
C3Z10_RS20100	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C3Z10_RS20105	COG2089	acid synthase
C3Z10_RS20110	COG0456	acetyltransferase
C3Z10_RS20115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C3Z10_RS20120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C3Z10_RS20125	COG0463	Glycosyl transferase, family 2
C3Z10_RS20135	COG2363	Small membrane protein
C3Z10_RS20140	COG2233	PERMEase
C3Z10_RS20155	COG1216	Glycosyl transferase, family 2
C3Z10_RS20160	COG0351	phosphomethylpyrimidine kinase
C3Z10_RS20170	COG1621	beta-fructofuranosidase activity
C3Z10_RS20175	COG1263	PTS System
C3Z10_RS20175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3Z10_RS20180	COG3711	transcriptional antiterminator
C3Z10_RS20190	COG1404	Belongs to the peptidase S8 family
C3Z10_RS20195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3Z10_RS20200	COG0778	Nitroreductase
C3Z10_RS20205	COG0772	Belongs to the SEDS family
C3Z10_RS20210	COG0454	-acetyltransferase
C3Z10_RS20230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C3Z10_RS20235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C3Z10_RS20240	COG2261	transglycosylase associated protein
C3Z10_RS20245	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C3Z10_RS20255	COG2246	polysaccharide biosynthetic process
C3Z10_RS20260	COG1309	transcriptional regulator
C3Z10_RS20280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C3Z10_RS20285	COG2837	iron assimilation
C3Z10_RS20290	COG2822	iron ion transport
C3Z10_RS20305	COG0583	DNA-binding transcription factor activity
C3Z10_RS20315	COG1346	cytolysis
C3Z10_RS20320	COG4895	conserved protein (DUF2196)
C3Z10_RS20325	COG0789	Transcriptional regulator
C3Z10_RS20330	COG5504	Zn-dependent protease
C3Z10_RS20335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C3Z10_RS20340	COG0346	lactoylglutathione lyase activity
C3Z10_RS20345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3Z10_RS20350	COG1404	Belongs to the peptidase S8 family
C3Z10_RS20355	COG1442	glycosyl transferase family 8
C3Z10_RS20365	COG2357	RelA SpoT domain protein
C3Z10_RS20370	COG1575	Belongs to the MenA family. Type 1 subfamily
C3Z10_RS20390	COG1696	Membrane protein involved in D-alanine export
C3Z10_RS20400	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C3Z10_RS20405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3Z10_RS20410	COG1486	melibiose metabolic process
C3Z10_RS20415	COG1447	Phosphotransferase system cellobiose-specific component IIA
C3Z10_RS20420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3Z10_RS20425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3Z10_RS20430	COG3711	transcriptional antiterminator
C3Z10_RS20430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3Z10_RS20445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3Z10_RS20450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3Z10_RS20460	COG0640	Transcriptional regulator
C3Z10_RS20465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3Z10_RS20470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3Z10_RS20475	COG1447	Phosphotransferase system cellobiose-specific component IIA
C3Z10_RS20480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3Z10_RS20485	COG2723	6-phospho-beta-galactosidase activity
C3Z10_RS20490	COG1940	carbohydrate kinase activity
C3Z10_RS20495	COG1482	cell wall glycoprotein biosynthetic process
C3Z10_RS20505	COG0753	catalase activity
C3Z10_RS20510	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C3Z10_RS20515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C3Z10_RS20520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C3Z10_RS20525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C3Z10_RS20530	COG4988	ABC transporter
C3Z10_RS20535	COG1294	oxidase, subunit
C3Z10_RS20540	COG1271	oxidase subunit
C3Z10_RS20545	COG3493	citrate carrier protein
C3Z10_RS20550	COG0726	polysaccharide deacetylase
C3Z10_RS20555	COG3842	ATPase activity
C3Z10_RS20560	COG2508	Transcriptional regulator
C3Z10_RS20565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3Z10_RS20575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3Z10_RS20585	COG4894	glucomannan catabolic process
C3Z10_RS20590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C3Z10_RS20595	COG0500	methyltransferase
C3Z10_RS20600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3Z10_RS20615	COG0693	protein deglycase activity
C3Z10_RS20615	COG0753	catalase activity
C3Z10_RS20620	COG2851	Citrate transporter
C3Z10_RS20625	COG2273	Hydrolase Family 16
C3Z10_RS20630	COG3711	transcriptional antiterminator
C3Z10_RS20635	COG2270	Major facilitator Superfamily
C3Z10_RS20640	COG0513	Belongs to the DEAD box helicase family
C3Z10_RS20690	COG3209	COG3209 Rhs family protein
C3Z10_RS20700	COG0697	spore germination
C3Z10_RS20705	COG0589	response to stress
C3Z10_RS20710	COG2723	6-phospho-beta-galactosidase activity
C3Z10_RS20715	COG1263	PTS System
C3Z10_RS20715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3Z10_RS20715	COG2190	(PTS) system
C3Z10_RS20725	COG3507	Belongs to the glycosyl hydrolase 43 family
C3Z10_RS20750	COG0010	Belongs to the arginase family
C3Z10_RS20755	COG0833	amino acid
C3Z10_RS20760	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C3Z10_RS20765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3Z10_RS20775	COG2390	Transcriptional regulator
C3Z10_RS20780	COG0561	phosphatase activity
C3Z10_RS20810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3Z10_RS20815	COG5294	Protein conserved in bacteria
C3Z10_RS20820	COG0577	efflux transmembrane transporter activity
C3Z10_RS20825	COG1136	(ABC) transporter
C3Z10_RS20830	COG2205	protein histidine kinase activity
C3Z10_RS20835	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS20840	COG2205	protein histidine kinase activity
C3Z10_RS20845	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS20875	COG1082	Xylose isomerase domain protein TIM barrel
C3Z10_RS20885	COG2814	Major facilitator Superfamily
C3Z10_RS20915	COG1349	DNA-binding transcription factor activity
C3Z10_RS20920	COG0667	Aldo Keto reductase
C3Z10_RS20925	COG2814	Major facilitator Superfamily
C3Z10_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS20945	COG2197	response regulator
C3Z10_RS20950	COG4585	Histidine kinase
C3Z10_RS20955	COG3239	Fatty acid desaturase
C3Z10_RS20965	COG1309	transcriptional regulator
C3Z10_RS20970	COG1012	belongs to the aldehyde dehydrogenase family
C3Z10_RS20975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C3Z10_RS20985	COG0640	Transcriptional regulator
C3Z10_RS20990	COG2814	Major facilitator Superfamily
C3Z10_RS20995	COG1714	RDD family
C3Z10_RS21005	COG0501	Belongs to the peptidase M48B family
C3Z10_RS21010	COG1715	Restriction endonuclease
C3Z10_RS21015	COG0450	alkyl hydroperoxide reductase
C3Z10_RS21020	COG3634	alkyl hydroperoxide reductase activity
C3Z10_RS21025	COG3177	Filamentation induced by cAMP protein fic
C3Z10_RS21030	COG1113	amino acid transport
C3Z10_RS21040	COG2080	2 iron, 2 sulfur cluster binding
C3Z10_RS21055	COG2068	MobA-Related Protein
C3Z10_RS21060	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C3Z10_RS21120	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C3Z10_RS21125	COG0667	Aldo Keto reductase
C3Z10_RS21130	COG0456	acetyltransferase
C3Z10_RS21135	COG0457	Tetratricopeptide repeat
C3Z10_RS21140	COG0010	Belongs to the arginase family
C3Z10_RS21145	COG0833	amino acid
C3Z10_RS21150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C3Z10_RS21155	COG5658	integral membrane protein
C3Z10_RS21160	COG0640	Transcriptional regulator
C3Z10_RS21165	COG3829	transcription factor binding
C3Z10_RS21175	COG0488	(ABC) transporter
C3Z10_RS21190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3Z10_RS21195	COG3850	Histidine kinase
C3Z10_RS21195	COG5002	protein histidine kinase activity
C3Z10_RS21200	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS21205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3Z10_RS21210	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C3Z10_RS21215	COG4853	Protein conserved in bacteria
C3Z10_RS21220	COG4863	YycH protein
C3Z10_RS21225	COG5002	protein histidine kinase activity
C3Z10_RS21230	COG0745	RESPONSE REGULATOR receiver
C3Z10_RS21265	COG0346	lactoylglutathione lyase activity
C3Z10_RS21270	COG0305	Participates in initiation and elongation during chromosome replication
C3Z10_RS21290	COG3093	addiction module antidote protein HigA
C3Z10_RS21295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C3Z10_RS21310	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C3Z10_RS21315	COG0438	transferase activity, transferring glycosyl groups
C3Z10_RS21335	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C3Z10_RS21340	COG4241	membrane
C3Z10_RS21350	COG5577	PFAM Coat F domain
C3Z10_RS21355	COG1733	regulation of RNA biosynthetic process
C3Z10_RS21365	COG0697	spore germination
C3Z10_RS21370	COG1621	beta-fructofuranosidase activity
C3Z10_RS21375	COG1621	beta-fructofuranosidase activity
C3Z10_RS21380	COG1802	Transcriptional regulator
C3Z10_RS21385	COG2318	DinB family
C3Z10_RS21390	COG2211	Major facilitator Superfamily
C3Z10_RS21395	COG0583	DNA-binding transcription factor activity
C3Z10_RS21410	COG0778	Nitroreductase
C3Z10_RS21415	COG1846	Transcriptional regulator
C3Z10_RS21420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3Z10_RS21425	COG1846	Transcriptional regulator
C3Z10_RS21430	COG2153	protein acetylation
C3Z10_RS21440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C3Z10_RS21445	COG0583	DNA-binding transcription factor activity
C3Z10_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
C3Z10_RS21455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3Z10_RS21460	COG0697	spore germination
C3Z10_RS21465	COG1331	Highly conserved protein containing a thioredoxin domain
C3Z10_RS21470	COG1266	CAAX protease self-immunity
C3Z10_RS21475	COG0477	Major facilitator Superfamily
C3Z10_RS21475	COG2814	Major facilitator Superfamily
C3Z10_RS21480	COG0346	lactoylglutathione lyase activity
C3Z10_RS21485	COG1609	Transcriptional regulator
C3Z10_RS21490	COG0708	Exodeoxyribonuclease III
C3Z10_RS21495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C3Z10_RS21500	COG2169	Transcriptional regulator
C3Z10_RS21510	COG0629	single-stranded DNA binding
C3Z10_RS21520	COG0012	GTP binding
C3Z10_RS21525	COG0243	molybdopterin cofactor binding
C3Z10_RS21530	COG4481	Protein conserved in bacteria
C3Z10_RS21535	COG3949	Membrane
C3Z10_RS21550	COG1475	DNA binding
C3Z10_RS21555	COG1192	Involved in chromosome partitioning
C3Z10_RS21580	COG1847	R3H domain protein
C3Z10_RS21585	COG0706	membrane insertase activity
C3Z10_RS21665	COG0791	NLP P60 protein
C3Z10_RS21665	COG3883	PFAM NLP P60 protein
C3Z10_RS21735	COG0629	single-stranded DNA binding
C3Z10_RS21750	COG0582	viral genome integration into host DNA
C3Z10_RS21790	COG1793	dna ligase
C3Z10_RS21805	COG1525	nuclease
C3Z10_RS21910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C3Z10_RS21950	COG0457	Tetratricopeptide repeat
C3Z10_RS21965	COG1396	sequence-specific DNA binding