locus-tag	class	description
IAR44_RS00010	COG0592	DNA-directed DNA polymerase activity
IAR44_RS00015	COG2501	S4 domain
IAR44_RS00030	COG0187	DNA topoisomerase II activity
IAR44_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAR44_RS00070	COG0517	IMP dehydrogenase activity
IAR44_RS00070	COG0516	GMP reductase activity
IAR44_RS00075	COG1686	Belongs to the peptidase S11 family
IAR44_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
IAR44_RS00105	COG1428	Deoxynucleoside kinase
IAR44_RS00110	COG1428	Deoxynucleoside kinase
IAR44_RS00115	COG3858	chitin binding
IAR44_RS00115	COG1388	LysM domain
IAR44_RS00120	COG1335	isochorismatase
IAR44_RS00125	COG0590	tRNA wobble adenosine to inosine editing
IAR44_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAR44_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IAR44_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAR44_RS00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IAR44_RS00200	COG3853	Toxic anion resistance protein (TelA)
IAR44_RS00205	COG1982	Orn Lys Arg decarboxylase major
IAR44_RS00215	COG3870	Protein conserved in bacteria
IAR44_RS00220	COG1728	Protein conserved in bacteria
IAR44_RS00225	COG0470	DNA polymerase III
IAR44_RS00230	COG1774	PSP1 C-terminal conserved region
IAR44_RS00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IAR44_RS00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IAR44_RS00255	COG2002	toxin-antitoxin pair type II binding
IAR44_RS00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAR44_RS00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAR44_RS00265	COG0084	hydrolase, TatD family'
IAR44_RS00270	COG3583	domain protein
IAR44_RS00270	COG3584	3D domain protein
IAR44_RS00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IAR44_RS00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAR44_RS00290	COG4466	Protein conserved in bacteria
IAR44_RS00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAR44_RS00310	COG0251	oxidation-reduction process
IAR44_RS00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAR44_RS00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAR44_RS00350	COG2002	toxin-antitoxin pair type II binding
IAR44_RS00355	COG2244	polysaccharide biosynthetic process
IAR44_RS00360	COG3956	TIGRFAM MazG family protein
IAR44_RS00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IAR44_RS00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IAR44_RS00385	COG1098	S1 RNA binding domain
IAR44_RS00400	COG2208	phosphoserine phosphatase activity
IAR44_RS00405	COG2304	oxidoreductase activity
IAR44_RS00410	COG0515	serine threonine protein kinase
IAR44_RS00415	COG0037	tRNA processing
IAR44_RS00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IAR44_RS00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAR44_RS00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAR44_RS00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAR44_RS00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAR44_RS00455	COG0512	Glutamine amidotransferase of anthranilate synthase
IAR44_RS00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAR44_RS00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IAR44_RS00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAR44_RS00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IAR44_RS00480	COG1396	sequence-specific DNA binding
IAR44_RS00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAR44_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IAR44_RS00570	COG4463	regulation of RNA biosynthetic process
IAR44_RS00575	COG3880	PFAM UvrB UvrC protein
IAR44_RS00585	COG0542	response to heat
IAR44_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IAR44_RS00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IAR44_RS00600	COG4956	integral membrane protein (PIN domain superfamily)
IAR44_RS00620	COG1045	serine acetyltransferase
IAR44_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IAR44_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAR44_RS00640	COG3688	RNA-binding protein containing a PIN domain
IAR44_RS00645	COG1595	DNA-templated transcription, initiation
IAR44_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAR44_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
IAR44_RS00685	COG2813	Specifically methylates the guanine in position
IAR44_RS00700	COG1358	cellular component organization or biogenesis
IAR44_RS00725	COG0596	Alpha beta hydrolase
IAR44_RS00835	COG0201	protein transport
IAR44_RS00845	COG0024	Methionine aminopeptidase
IAR44_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IAR44_RS00880	COG1122	ATPase activity
IAR44_RS00885	COG1122	ATPase activity
IAR44_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAR44_RS00910	COG2226	methyltransferase
IAR44_RS00915	COG2318	DinB family
IAR44_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAR44_RS00930	COG0489	protein tyrosine kinase activity
IAR44_RS00940	COG2194	sulfuric ester hydrolase activity
IAR44_RS00945	COG0726	polysaccharide deacetylase
IAR44_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAR44_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
IAR44_RS01030	COG0385	Bile acid
IAR44_RS01035	COG2819	hydrolase of the alpha beta superfamily
IAR44_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAR44_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAR44_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAR44_RS01055	COG2207	Transcriptional regulator
IAR44_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAR44_RS01060	COG3876	Protein conserved in bacteria
IAR44_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
IAR44_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAR44_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAR44_RS01075	COG1263	PTS System
IAR44_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAR44_RS01090	COG1683	Conserved Protein
IAR44_RS01120	COG1595	DNA-templated transcription, initiation
IAR44_RS01125	COG5662	AntiSigma factor
IAR44_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IAR44_RS01135	COG4856	YbbR-like protein
IAR44_RS01175	COG1346	cytolysis
IAR44_RS01180	COG1380	Effector of murein hydrolase LrgA
IAR44_RS01185	COG1846	Transcriptional regulator
IAR44_RS01190	COG1113	amino acid transport
IAR44_RS01195	COG1011	Hydrolase
IAR44_RS01200	COG4585	Histidine kinase
IAR44_RS01205	COG2197	response regulator
IAR44_RS01210	COG1131	(ABC) transporter
IAR44_RS01230	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IAR44_RS01250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS01250	COG3321	synthase
IAR44_RS01250	COG4221	oxidoreductase activity
IAR44_RS01250	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS01255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS01255	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS01255	COG0300	oxidoreductase activity
IAR44_RS01255	COG3321	synthase
IAR44_RS01295	COG0531	amino acid
IAR44_RS01305	COG0584	glycerophosphoryl diester phosphodiesterase
IAR44_RS01310	COG2271	Major facilitator Superfamily
IAR44_RS01320	COG2368	4-hydroxyphenylacetate
IAR44_RS01345	COG0371	Dehydrogenase
IAR44_RS01355	COG1183	phosphatidylcholine synthase activity
IAR44_RS01360	COG0586	Pfam SNARE associated Golgi protein
IAR44_RS01365	COG0688	phosphatidylethanolamine metabolic process
IAR44_RS01380	COG1301	dicarboxylic acid transport
IAR44_RS01385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAR44_RS01390	COG0833	amino acid
IAR44_RS01395	COG2040	homocysteine
IAR44_RS01400	COG1115	amino acid carrier protein
IAR44_RS01405	COG2066	Belongs to the glutaminase family
IAR44_RS01410	COG4191	Histidine kinase
IAR44_RS01415	COG0784	Response regulator, receiver
IAR44_RS01435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAR44_RS01440	COG0778	Nitroreductase
IAR44_RS01445	COG0346	lactoylglutathione lyase activity
IAR44_RS01450	COG2259	Doxx family
IAR44_RS01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAR44_RS01465	COG3773	Cell wall hydrolase
IAR44_RS01470	COG3540	Alkaline phosphatase
IAR44_RS01475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAR44_RS01480	COG0805	protein transport
IAR44_RS01490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAR44_RS01495	COG0477	Major facilitator Superfamily
IAR44_RS01500	COG1309	transcriptional regulator
IAR44_RS01505	COG0252	asparaginase activity
IAR44_RS01510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IAR44_RS01515	COG3012	SEC-C Motif Domain Protein
IAR44_RS01515	COG1405	negative regulation of cell septum assembly
IAR44_RS01520	COG0667	Aldo Keto reductase
IAR44_RS01530	COG1595	DNA-templated transcription, initiation
IAR44_RS01535	COG1595	DNA-templated transcription, initiation
IAR44_RS01540	COG1876	peptidase activity
IAR44_RS01545	COG0457	Tetratricopeptide repeat
IAR44_RS01550	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS01555	COG0366	Alpha amylase catalytic
IAR44_RS01560	COG0803	Belongs to the bacterial solute-binding protein 9 family
IAR44_RS01565	COG1121	(ABC) transporter
IAR44_RS01570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAR44_RS01575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAR44_RS01580	COG2310	stress, protein
IAR44_RS01585	COG2310	stress, protein
IAR44_RS01590	COG2310	stress, protein
IAR44_RS01595	COG0861	Integral membrane protein TerC family
IAR44_RS01605	COG3853	Toxic anion resistance protein (TelA)
IAR44_RS01610	COG0477	Major facilitator Superfamily
IAR44_RS01615	COG0517	IMP dehydrogenase activity
IAR44_RS01615	COG4175	Glycine betaine
IAR44_RS01620	COG4176	ABC-type proline glycine betaine transport system permease component
IAR44_RS01625	COG2113	Glycine betaine
IAR44_RS01630	COG1473	amidohydrolase
IAR44_RS01635	COG1288	antiporter activity
IAR44_RS01645	COG0366	Alpha amylase catalytic
IAR44_RS01655	COG2814	Major facilitator Superfamily
IAR44_RS01660	COG1846	Transcriptional regulator
IAR44_RS01665	COG1280	lysine exporter protein (LysE YggA)
IAR44_RS01670	COG3403	YqcI/YcgG family
IAR44_RS01675	COG1113	amino acid transport
IAR44_RS01680	COG3665	Urea carboxylase-associated protein
IAR44_RS01695	COG1660	Displays ATPase and GTPase activities
IAR44_RS01700	COG1082	Xylose isomerase domain protein TIM barrel
IAR44_RS01705	COG2271	Major facilitator Superfamily
IAR44_RS01710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAR44_RS01715	COG3458	cephalosporin-C deacetylase activity
IAR44_RS01720	COG3541	Predicted nucleotidyltransferase
IAR44_RS01725	COG0506	proline dehydrogenase activity
IAR44_RS01730	COG1012	belongs to the aldehyde dehydrogenase family
IAR44_RS01735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAR44_RS01740	COG2508	Transcriptional regulator
IAR44_RS01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAR44_RS01750	COG1587	Uroporphyrinogen-III synthase
IAR44_RS01755	COG2146	nitrite reductase [NAD(P)H] activity
IAR44_RS01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAR44_RS01765	COG0243	molybdopterin cofactor binding
IAR44_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAR44_RS01775	COG2223	nitrite transmembrane transporter activity
IAR44_RS01780	COG0523	cobalamin synthesis protein
IAR44_RS01785	COG1063	alcohol dehydrogenase
IAR44_RS01790	COG1714	RDD family
IAR44_RS01800	COG2723	6-phospho-beta-galactosidase activity
IAR44_RS01810	COG3209	COG3209 Rhs family protein
IAR44_RS01815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IAR44_RS01820	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IAR44_RS01825	COG1733	regulation of RNA biosynthetic process
IAR44_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS01845	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IAR44_RS01860	COG0697	spore germination
IAR44_RS01865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAR44_RS01875	COG2364	Membrane
IAR44_RS01880	COG1126	abc transporter atp-binding protein
IAR44_RS01885	COG0765	amino acid transport
IAR44_RS01890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAR44_RS01895	COG0583	DNA-binding transcription factor activity
IAR44_RS01900	COG0163	prenyltransferase activity
IAR44_RS01905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IAR44_RS01920	COG3104	oligopeptide transport
IAR44_RS01925	COG5434	Belongs to the glycosyl hydrolase 28 family
IAR44_RS01935	COG0697	spore germination
IAR44_RS01945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IAR44_RS01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAR44_RS01955	COG0456	acetyltransferase
IAR44_RS01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAR44_RS01965	COG0765	amino acid transport
IAR44_RS01970	COG1126	abc transporter atp-binding protein
IAR44_RS01975	COG1473	amidohydrolase
IAR44_RS01980	COG2079	MmgE PrpD family protein
IAR44_RS01985	COG1136	(ABC) transporter
IAR44_RS01990	COG0577	efflux transmembrane transporter activity
IAR44_RS01995	COG0745	RESPONSE REGULATOR receiver
IAR44_RS02000	COG3850	Histidine kinase
IAR44_RS02000	COG5002	protein histidine kinase activity
IAR44_RS02005	COG0457	Tetratricopeptide repeat
IAR44_RS02020	COG0527	aspartate kinase activity
IAR44_RS02025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAR44_RS02030	COG4605	iron ion homeostasis
IAR44_RS02035	COG4604	ABC transporter, ATP-binding protein
IAR44_RS02040	COG4607	ABC-type enterochelin transport system periplasmic component
IAR44_RS02045	COG2814	Major facilitator Superfamily
IAR44_RS02050	COG1309	transcriptional regulator
IAR44_RS02055	COG0778	Nitroreductase
IAR44_RS02060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IAR44_RS02065	COG0640	Transcriptional regulator
IAR44_RS02070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAR44_RS02075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAR44_RS02080	COG1012	belongs to the aldehyde dehydrogenase family
IAR44_RS02085	COG4975	Glucose uptake
IAR44_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS02095	COG4549	nuclear export factor GLE1
IAR44_RS02100	COG1276	copper resistance
IAR44_RS02100	COG2372	response to copper ion
IAR44_RS02105	COG1349	DNA-binding transcription factor activity
IAR44_RS02115	COG2213	PTS system mannitol-specific
IAR44_RS02120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAR44_RS02130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IAR44_RS02140	COG0561	phosphatase activity
IAR44_RS02150	COG1914	H( )-stimulated, divalent metal cation uptake system
IAR44_RS02160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IAR44_RS02165	COG1984	allophanate hydrolase subunit 2
IAR44_RS02170	COG1414	Transcriptional regulator
IAR44_RS02175	COG2755	lipolytic protein G-D-S-L family
IAR44_RS02185	COG2329	Antibiotic biosynthesis monooxygenase
IAR44_RS02190	COG0768	penicillin binding
IAR44_RS02195	COG4989	oxidoreductase activity
IAR44_RS02200	COG3711	transcriptional antiterminator
IAR44_RS02205	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS02215	COG1917	Cupin 2, conserved barrel domain protein
IAR44_RS02220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAR44_RS02225	COG3871	stress protein (general stress protein 26)
IAR44_RS02240	COG2814	Major facilitator Superfamily
IAR44_RS02245	COG1522	sequence-specific DNA binding
IAR44_RS02250	COG0551	DNA topoisomerase type I activity
IAR44_RS02250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAR44_RS02255	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IAR44_RS02260	COG3706	GGDEF domain
IAR44_RS02265	COG5298	Protein conserved in bacteria
IAR44_RS02270	COG1215	transferase activity, transferring glycosyl groups
IAR44_RS02280	COG0531	amino acid
IAR44_RS02285	COG0494	nUDIX hydrolase
IAR44_RS02290	COG0028	Belongs to the TPP enzyme family
IAR44_RS02310	COG1914	H( )-stimulated, divalent metal cation uptake system
IAR44_RS02320	COG4876	unkown
IAR44_RS02330	COG2076	Multidrug Resistance protein
IAR44_RS02335	COG2217	Heavy metal translocating P-type atpase
IAR44_RS02340	COG3729	General stress protein
IAR44_RS02345	COG0662	Cupin 2, conserved barrel domain protein
IAR44_RS02350	COG2329	Antibiotic biosynthesis monooxygenase
IAR44_RS02355	COG3546	catalase activity
IAR44_RS02360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAR44_RS02365	COG3290	protein histidine kinase activity
IAR44_RS02370	COG4565	transcriptional regulatory protein
IAR44_RS02375	COG1301	dicarboxylic acid transport
IAR44_RS02380	COG0628	permease
IAR44_RS02385	COG1131	(ABC) transporter
IAR44_RS02390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IAR44_RS02400	COG1960	acyl-CoA dehydrogenase activity
IAR44_RS02415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAR44_RS02420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAR44_RS02430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IAR44_RS02435	COG0513	Belongs to the DEAD box helicase family
IAR44_RS02440	COG3402	PFAM membrane-flanked domain
IAR44_RS02445	COG3428	Bacterial PH domain
IAR44_RS02450	COG0705	Rhomboid family
IAR44_RS02460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IAR44_RS02465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAR44_RS02470	COG0864	Transcriptional regulator
IAR44_RS02475	COG2337	Toxic component of a toxin-antitoxin (TA) module
IAR44_RS02480	COG1366	Belongs to the anti-sigma-factor antagonist family
IAR44_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
IAR44_RS02490	COG2172	sigma factor antagonist activity
IAR44_RS02495	COG2208	phosphoserine phosphatase activity
IAR44_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
IAR44_RS02510	COG1191	sigma factor activity
IAR44_RS02515	COG2208	phosphoserine phosphatase activity
IAR44_RS02520	COG2183	response to ionizing radiation
IAR44_RS02595	COG5444	nuclease activity
IAR44_RS02600	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAR44_RS02615	COG0477	Major facilitator Superfamily
IAR44_RS02620	COG1846	Transcriptional regulator
IAR44_RS02630	COG2030	dehydratase
IAR44_RS02640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAR44_RS02645	COG1959	2 iron, 2 sulfur cluster binding
IAR44_RS02650	COG2910	NAD(P)H-binding
IAR44_RS02655	COG1278	Cold shock
IAR44_RS02660	COG1329	Transcriptional regulator
IAR44_RS02665	COG1794	racemase activity, acting on amino acids and derivatives
IAR44_RS02690	COG0662	Cupin 2, conserved barrel domain protein
IAR44_RS02705	COG0277	FAD linked oxidase domain protein
IAR44_RS02725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAR44_RS02760	COG0351	phosphomethylpyrimidine kinase
IAR44_RS02775	COG1064	alcohol dehydrogenase
IAR44_RS02780	COG0789	Transcriptional regulator
IAR44_RS02790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAR44_RS02805	COG2814	Major facilitator Superfamily
IAR44_RS02810	COG1309	transcriptional regulator
IAR44_RS02815	COG0697	spore germination
IAR44_RS02820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAR44_RS02825	COG5577	PFAM Coat F domain
IAR44_RS02835	COG1063	alcohol dehydrogenase
IAR44_RS02840	COG5577	PFAM Coat F domain
IAR44_RS02850	COG4585	Histidine kinase
IAR44_RS02855	COG2197	response regulator
IAR44_RS02860	COG2409	Drug exporters of the RND superfamily
IAR44_RS02865	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IAR44_RS02870	COG0488	(ABC) transporter
IAR44_RS02875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAR44_RS02880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAR44_RS02890	COG2814	Major facilitator Superfamily
IAR44_RS02895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAR44_RS02905	COG0730	response to heat
IAR44_RS02910	COG0456	acetyltransferase
IAR44_RS02920	COG1051	belongs to the nudix hydrolase family
IAR44_RS02925	COG2226	methyltransferase
IAR44_RS02945	COG1802	Transcriptional regulator
IAR44_RS02950	COG1819	glycosyl
IAR44_RS02965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAR44_RS02975	COG1388	LysM domain
IAR44_RS02980	COG2814	Major facilitator Superfamily
IAR44_RS02985	COG2188	Transcriptional regulator
IAR44_RS02990	COG2186	Transcriptional regulator
IAR44_RS02995	COG2807	transmembrane transport
IAR44_RS03000	COG2076	Multidrug Resistance protein
IAR44_RS03005	COG2076	Multidrug Resistance protein
IAR44_RS03010	COG1309	transcriptional regulator
IAR44_RS03015	COG0531	amino acid
IAR44_RS03025	COG3832	glyoxalase III activity
IAR44_RS03030	COG0604	alcohol dehydrogenase
IAR44_RS03035	COG2814	Major facilitator Superfamily
IAR44_RS03075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IAR44_RS03080	COG0802	atpase or kinase
IAR44_RS03085	COG1214	PFAM Peptidase M22, glycoprotease
IAR44_RS03090	COG0456	acetyltransferase
IAR44_RS03095	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAR44_RS03100	COG0488	(ABC) transporter
IAR44_RS03115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAR44_RS03120	COG0805	protein transport
IAR44_RS03130	COG1266	CAAX protease self-immunity
IAR44_RS03145	COG0745	RESPONSE REGULATOR receiver
IAR44_RS03160	COG3290	protein histidine kinase activity
IAR44_RS03240	COG0457	Tetratricopeptide repeat
IAR44_RS03245	COG1063	alcohol dehydrogenase
IAR44_RS03250	COG2211	Major facilitator Superfamily
IAR44_RS03255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAR44_RS03265	COG1842	Phage shock protein A
IAR44_RS03270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAR44_RS03275	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IAR44_RS03280	COG4260	virion core protein, lumpy skin disease virus
IAR44_RS03285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAR44_RS03285	COG2755	lipolytic protein G-D-S-L family
IAR44_RS03295	COG1595	DNA-templated transcription, initiation
IAR44_RS03300	COG1063	alcohol dehydrogenase
IAR44_RS03305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IAR44_RS03310	COG0823	Involved in the tonB-independent uptake of proteins
IAR44_RS03325	COG2132	Multicopper oxidase
IAR44_RS03330	COG1113	amino acid transport
IAR44_RS03335	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAR44_RS03340	COG0714	Associated with various cellular activities
IAR44_RS03345	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
IAR44_RS03350	COG1305	Transglutaminase-like
IAR44_RS03375	COG2252	PERMEase
IAR44_RS03380	COG3064	Membrane
IAR44_RS03400	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IAR44_RS03405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAR44_RS03410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAR44_RS03415	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IAR44_RS03420	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAR44_RS03435	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IAR44_RS03445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAR44_RS03450	COG0138	bifunctional purine biosynthesis protein purh
IAR44_RS03455	COG0151	Belongs to the GarS family
IAR44_RS03465	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IAR44_RS03470	COG1470	cell adhesion involved in biofilm formation
IAR44_RS03475	COG4496	protein, YerC YecD
IAR44_RS03480	COG0069	glutamate synthase activity
IAR44_RS03490	COG0210	DNA helicase
IAR44_RS03500	COG4851	CamS sex pheromone cAM373 precursor
IAR44_RS03505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IAR44_RS03510	COG1285	pathogenesis
IAR44_RS03515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAR44_RS03535	COG1309	transcriptional regulator
IAR44_RS03540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAR44_RS03545	COG1597	lipid kinase activity
IAR44_RS03550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAR44_RS03555	COG1106	Psort location Cytoplasmic, score
IAR44_RS03585	COG5444	nuclease activity
IAR44_RS03610	COG3546	catalase activity
IAR44_RS03615	COG0454	-acetyltransferase
IAR44_RS03625	COG2323	membrane
IAR44_RS03630	COG2329	Antibiotic biosynthesis monooxygenase
IAR44_RS03635	COG0346	lactoylglutathione lyase activity
IAR44_RS03640	COG1366	Belongs to the anti-sigma-factor antagonist family
IAR44_RS03645	COG5583	Uncharacterized small protein (DUF2292)
IAR44_RS03650	COG0196	riboflavin kinase activity
IAR44_RS03655	COG0670	Belongs to the BI1 family
IAR44_RS03660	COG1846	Transcriptional regulator
IAR44_RS03665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAR44_RS03675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IAR44_RS03675	COG2124	cytochrome p450
IAR44_RS03680	COG1368	sulfuric ester hydrolase activity
IAR44_RS03685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IAR44_RS03690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAR44_RS03695	COG1442	glycosyl transferase family 8
IAR44_RS03700	COG1216	Glycosyl transferase, family 2
IAR44_RS03705	COG1442	glycosyl transferase family 8
IAR44_RS03710	COG2223	nitrite transmembrane transporter activity
IAR44_RS03715	COG0531	amino acid
IAR44_RS03720	COG1012	belongs to the aldehyde dehydrogenase family
IAR44_RS03725	COG0840	transmembrane signaling receptor activity
IAR44_RS03730	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS03735	COG0457	Tetratricopeptide repeat
IAR44_RS03735	COG0463	Glycosyl transferase, family 2
IAR44_RS03740	COG0488	(ABC) transporter
IAR44_RS03745	COG0789	Transcriptional regulator
IAR44_RS03750	COG2814	Major facilitator Superfamily
IAR44_RS03755	COG0488	(ABC) transporter
IAR44_RS03760	COG0513	Belongs to the DEAD box helicase family
IAR44_RS03765	COG0456	acetyltransferase
IAR44_RS03770	COG2130	NADP-dependent
IAR44_RS03785	COG3866	Pectate lyase
IAR44_RS03790	COG0471	metal ion transport
IAR44_RS03805	COG3290	protein histidine kinase activity
IAR44_RS03810	COG4565	transcriptional regulatory protein
IAR44_RS03815	COG3181	Tripartite tricarboxylate transporter family receptor
IAR44_RS03820	COG2851	Citrate transporter
IAR44_RS03825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAR44_RS03830	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IAR44_RS03840	COG2258	MOSC domain
IAR44_RS03860	COG0024	Methionine aminopeptidase
IAR44_RS03865	COG1263	PTS System
IAR44_RS03865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAR44_RS03875	COG1368	sulfuric ester hydrolase activity
IAR44_RS03885	COG0071	Belongs to the small heat shock protein (HSP20) family
IAR44_RS03900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAR44_RS03900	COG1263	PTS System
IAR44_RS03905	COG0366	Alpha amylase catalytic
IAR44_RS03910	COG2188	Transcriptional regulator
IAR44_RS03915	COG0778	Nitroreductase
IAR44_RS03930	COG0737	Belongs to the 5'-nucleotidase family
IAR44_RS03935	COG0693	protein deglycase activity
IAR44_RS03940	COG1609	Transcriptional regulator
IAR44_RS03955	COG2814	Major facilitator Superfamily
IAR44_RS03965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAR44_RS03970	COG4980	gas vesicle protein
IAR44_RS03975	COG1295	ribonuclease BN
IAR44_RS03980	COG0477	Major facilitator Superfamily
IAR44_RS03985	COG0387	Pfam Sodium calcium exchanger
IAR44_RS03995	COG0668	transmembrane transport
IAR44_RS04000	COG0535	radical SAM domain protein
IAR44_RS04010	COG0726	polysaccharide deacetylase
IAR44_RS04015	COG2084	Dehydrogenase
IAR44_RS04025	COG0598	Magnesium transport protein CorA
IAR44_RS04030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IAR44_RS04035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAR44_RS04050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAR44_RS04055	COG4637	Psort location Cytoplasmic, score
IAR44_RS04060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAR44_RS04065	COG0022	dehydrogenase e1 component
IAR44_RS04070	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAR44_RS04075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAR44_RS04080	COG3284	Transcriptional regulator
IAR44_RS04090	COG1486	melibiose metabolic process
IAR44_RS04095	COG1737	Transcriptional regulator
IAR44_RS04100	COG1263	PTS System
IAR44_RS04100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAR44_RS04105	COG5434	Belongs to the glycosyl hydrolase 28 family
IAR44_RS04110	COG1132	(ABC) transporter
IAR44_RS04115	COG1132	(ABC) transporter
IAR44_RS04120	COG2259	Doxx family
IAR44_RS04125	COG2514	catechol 2,3-dioxygenase activity
IAR44_RS04135	COG1695	Transcriptional regulator
IAR44_RS04140	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAR44_RS04145	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IAR44_RS04150	COG3848	Pyruvate phosphate dikinase
IAR44_RS04150	COG0574	Belongs to the PEP-utilizing enzyme family
IAR44_RS04155	COG2732	(Barnase) inhibitor
IAR44_RS04160	COG2318	DinB family
IAR44_RS04165	COG2814	Major facilitator Superfamily
IAR44_RS04170	COG1846	Transcriptional regulator
IAR44_RS04175	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAR44_RS04175	COG0392	lysyltransferase activity
IAR44_RS04180	COG0384	phenazine biosynthesis protein PhzF
IAR44_RS04185	COG0778	Nitroreductase
IAR44_RS04200	COG1090	epimerase
IAR44_RS04215	COG2814	Major facilitator Superfamily
IAR44_RS04225	COG3591	Belongs to the peptidase S1B family
IAR44_RS04240	COG3103	Sh3 type 3 domain protein
IAR44_RS04245	COG5658	integral membrane protein
IAR44_RS04250	COG0596	Alpha beta hydrolase
IAR44_RS04255	COG0463	Glycosyl transferase, family 2
IAR44_RS04260	COG4485	Bacterial membrane protein, YfhO
IAR44_RS04265	COG1988	membrane-bound metal-dependent
IAR44_RS04270	COG1194	a g-specific adenine glycosylase
IAR44_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS04300	COG1132	(ABC) transporter
IAR44_RS04305	COG4129	membrane
IAR44_RS04315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAR44_RS04320	COG0735	belongs to the Fur family
IAR44_RS04435	COG3340	Belongs to the peptidase S51 family
IAR44_RS04445	COG0277	FAD linked oxidase domain protein
IAR44_RS04455	COG0747	negative chemotaxis
IAR44_RS04460	COG0601	transmembrane transport
IAR44_RS04465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAR44_RS04470	COG0444	Belongs to the ABC transporter superfamily
IAR44_RS04475	COG4608	Belongs to the ABC transporter superfamily
IAR44_RS04480	COG0753	catalase activity
IAR44_RS04490	COG1116	anion transmembrane transporter activity
IAR44_RS04495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAR44_RS04500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAR44_RS04520	COG1476	TRANSCRIPTIONal
IAR44_RS04530	COG3382	B3 4 domain protein
IAR44_RS04535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IAR44_RS04545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IAR44_RS04550	COG0789	Transcriptional regulator
IAR44_RS04555	COG1664	Polymer-forming cytoskeletal
IAR44_RS04560	COG1664	Polymer-forming cytoskeletal
IAR44_RS04565	COG2766	serine protein kinase
IAR44_RS04575	COG1846	Transcriptional regulator
IAR44_RS04580	COG1566	PFAM secretion protein HlyD family protein
IAR44_RS04585	COG2814	Major facilitator Superfamily
IAR44_RS04590	COG0655	NAD(P)H dehydrogenase (quinone) activity
IAR44_RS04605	COG1725	Transcriptional regulator
IAR44_RS04610	COG1131	(ABC) transporter
IAR44_RS04615	COG1131	(ABC) transporter
IAR44_RS04620	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IAR44_RS04625	COG1278	Cold shock
IAR44_RS04630	COG1464	Belongs to the NlpA lipoprotein family
IAR44_RS04635	COG3706	GGDEF domain
IAR44_RS04640	COG1823	symporter activity
IAR44_RS04660	COG5577	PFAM Coat F domain
IAR44_RS04670	COG3764	Sortase (surface protein transpeptidase)
IAR44_RS04675	COG0564	pseudouridine synthase activity
IAR44_RS04685	COG0517	IMP dehydrogenase activity
IAR44_RS04690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAR44_RS04695	COG3153	acetyltransferase
IAR44_RS04695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAR44_RS04705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAR44_RS04710	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IAR44_RS04715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IAR44_RS04725	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IAR44_RS04730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAR44_RS04740	COG2197	response regulator
IAR44_RS04745	COG0431	NADPH-dependent FMN reductase
IAR44_RS04760	COG0791	NLP P60 protein
IAR44_RS04760	COG1388	LysM domain
IAR44_RS04765	COG1959	2 iron, 2 sulfur cluster binding
IAR44_RS04770	COG0668	transmembrane transport
IAR44_RS04775	COG2719	SpoVR family
IAR44_RS04780	COG1785	Belongs to the alkaline phosphatase family
IAR44_RS04785	COG1388	LysM domain
IAR44_RS04785	COG0791	NLP P60 protein
IAR44_RS04790	COG0583	DNA-binding transcription factor activity
IAR44_RS04795	COG0372	Belongs to the citrate synthase family
IAR44_RS04800	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS04805	COG0531	amino acid
IAR44_RS04810	COG0733	neurotransmitter:sodium symporter activity
IAR44_RS04825	COG1595	DNA-templated transcription, initiation
IAR44_RS04830	COG0204	Acyl-transferase
IAR44_RS04835	COG1253	flavin adenine dinucleotide binding
IAR44_RS04840	COG0789	Transcriptional regulator
IAR44_RS04845	COG0436	Aminotransferase
IAR44_RS04850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAR44_RS04855	COG1253	flavin adenine dinucleotide binding
IAR44_RS04860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAR44_RS04865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAR44_RS04870	COG0584	glycerophosphoryl diester phosphodiesterase
IAR44_RS04880	COG0668	transmembrane transport
IAR44_RS04885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAR44_RS04890	COG0726	polysaccharide deacetylase
IAR44_RS04895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAR44_RS04900	COG3226	Transcriptional regulator
IAR44_RS04910	COG0589	response to stress
IAR44_RS04915	COG1132	(ABC) transporter
IAR44_RS04920	COG1132	(ABC) transporter
IAR44_RS04925	COG0702	epimerase
IAR44_RS04940	COG0189	ligase activity
IAR44_RS04945	COG0189	ligase activity
IAR44_RS04960	COG4335	DNA alkylation repair
IAR44_RS04965	COG0561	phosphatase activity
IAR44_RS04970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAR44_RS04980	COG0475	glutathione-regulated potassium exporter activity
IAR44_RS04985	COG0490	domain, Protein
IAR44_RS04995	COG1024	Enoyl-CoA hydratase
IAR44_RS05005	COG4152	abc transporter atp-binding protein
IAR44_RS05010	COG1668	transmembrane transport
IAR44_RS05015	COG0420	3'-5' exonuclease activity
IAR44_RS05020	COG4717	serine-type aminopeptidase activity
IAR44_RS05035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAR44_RS05070	COG4980	gas vesicle protein
IAR44_RS05085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IAR44_RS05090	COG0537	adenosine 5'-monophosphoramidase activity
IAR44_RS05095	COG1131	(ABC) transporter
IAR44_RS05100	COG4473	ABC transporter
IAR44_RS05110	COG1473	amidohydrolase
IAR44_RS05115	COG3069	C4-dicarboxylate transmembrane transporter activity
IAR44_RS05120	COG2329	Antibiotic biosynthesis monooxygenase
IAR44_RS05125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAR44_RS05135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IAR44_RS05140	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IAR44_RS05145	COG1309	transcriptional regulator
IAR44_RS05150	COG1511	domain protein
IAR44_RS05155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAR44_RS05165	COG1363	Peptidase, m42
IAR44_RS05170	COG1301	dicarboxylic acid transport
IAR44_RS05180	COG1234	tRNA 3'-trailer cleavage
IAR44_RS05185	COG0095	Lipoate-protein ligase
IAR44_RS05190	COG0702	epimerase
IAR44_RS05195	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS05205	COG0501	Belongs to the peptidase M48B family
IAR44_RS05210	COG1404	Belongs to the peptidase S8 family
IAR44_RS05215	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IAR44_RS05220	COG0406	alpha-ribazole phosphatase activity
IAR44_RS05225	COG0183	Belongs to the thiolase family
IAR44_RS05230	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS05235	COG1268	BioY protein
IAR44_RS05240	COG0840	transmembrane signaling receptor activity
IAR44_RS05245	COG0723	plastoquinol--plastocyanin reductase activity
IAR44_RS05245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAR44_RS05250	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS05260	COG4903	ComK protein
IAR44_RS05270	COG5646	InterPro IPR014922
IAR44_RS05295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAR44_RS05310	COG0398	Pfam SNARE associated Golgi protein
IAR44_RS05315	COG0681	Belongs to the peptidase S26 family
IAR44_RS05320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAR44_RS05325	COG1846	Transcriptional regulator
IAR44_RS05330	COG3180	Ammonia monooxygenase
IAR44_RS05335	COG2814	Major facilitator Superfamily
IAR44_RS05345	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IAR44_RS05365	COG0420	3'-5' exonuclease activity
IAR44_RS05370	COG0419	ATPase involved in DNA repair
IAR44_RS05375	COG1403	HNH endonuclease
IAR44_RS05415	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAR44_RS05435	COG0367	asparagine synthase
IAR44_RS05440	COG1562	ergosterol biosynthetic process
IAR44_RS05445	COG0534	Mate efflux family protein
IAR44_RS05450	COG2207	Transcriptional regulator
IAR44_RS05450	COG1917	Cupin 2, conserved barrel domain protein
IAR44_RS05455	COG2318	DinB family
IAR44_RS05460	COG1279	arginine transmembrane transporter activity
IAR44_RS05465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAR44_RS05470	COG1357	PFAM Pentapeptide repeats (8 copies)
IAR44_RS05475	COG2153	protein acetylation
IAR44_RS05480	COG0646	methionine synthase
IAR44_RS05480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IAR44_RS05490	COG2996	Protein conserved in bacteria
IAR44_RS05495	COG1744	ABC transporter substrate-binding protein PnrA-like
IAR44_RS05500	COG0840	transmembrane signaling receptor activity
IAR44_RS05505	COG2124	cytochrome p450
IAR44_RS05515	COG1307	EDD domain protein, DegV family
IAR44_RS05520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAR44_RS05540	COG0561	phosphatase activity
IAR44_RS05545	COG1073	alpha beta
IAR44_RS05550	COG2151	metal-sulfur cluster biosynthetic enzyme
IAR44_RS05585	COG0277	FAD linked oxidase domain protein
IAR44_RS05590	COG2271	Major facilitator Superfamily
IAR44_RS05600	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAR44_RS05610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAR44_RS05615	COG0505	Belongs to the CarA family
IAR44_RS05620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAR44_RS05625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAR44_RS05640	COG2267	carboxylic ester hydrolase activity
IAR44_RS05650	COG1744	ABC transporter substrate-binding protein PnrA-like
IAR44_RS05665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAR44_RS05670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAR44_RS05675	COG5504	Zn-dependent protease
IAR44_RS05680	COG0444	Belongs to the ABC transporter superfamily
IAR44_RS05685	COG4608	Belongs to the ABC transporter superfamily
IAR44_RS05695	COG0601	transmembrane transport
IAR44_RS05700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAR44_RS05710	COG0180	Tryptophanyl-tRNA synthetase
IAR44_RS05715	COG4166	transmembrane transport
IAR44_RS05720	COG0601	transmembrane transport
IAR44_RS05725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAR44_RS05730	COG0444	Belongs to the ABC transporter superfamily
IAR44_RS05735	COG4608	Belongs to the ABC transporter superfamily
IAR44_RS05745	COG0456	acetyltransferase
IAR44_RS05750	COG1393	Belongs to the ArsC family
IAR44_RS05755	COG0861	Integral membrane protein TerC family
IAR44_RS05760	COG4862	establishment of competence for transformation
IAR44_RS05765	COG4469	Competence protein
IAR44_RS05770	COG1164	Oligoendopeptidase f
IAR44_RS05780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAR44_RS05785	COG2346	COG2346, Truncated hemoglobins
IAR44_RS05790	COG0741	lytic transglycosylase activity
IAR44_RS05795	COG4116	CYTH
IAR44_RS05805	COG2357	RelA SpoT domain protein
IAR44_RS05810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAR44_RS05815	COG0564	pseudouridine synthase activity
IAR44_RS05825	COG0569	domain protein
IAR44_RS05825	COG0475	glutathione-regulated potassium exporter activity
IAR44_RS05830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAR44_RS05835	COG0352	thiamine-phosphate diphosphorylase activity
IAR44_RS05840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAR44_RS05845	COG2104	thiamine diphosphate biosynthetic process
IAR44_RS05855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAR44_RS05860	COG0351	phosphomethylpyrimidine kinase
IAR44_RS05865	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IAR44_RS05920	COG0210	DNA helicase
IAR44_RS05940	COG1131	(ABC) transporter
IAR44_RS05950	COG2153	protein acetylation
IAR44_RS05960	COG2382	esterase
IAR44_RS05965	COG0626	cystathionine gamma-synthase activity
IAR44_RS05970	COG0626	cystathionine gamma-synthase activity
IAR44_RS06000	COG5444	nuclease activity
IAR44_RS06085	COG0537	adenosine 5'-monophosphoramidase activity
IAR44_RS06090	COG0135	phosphoribosylanthranilate isomerase activity
IAR44_RS06100	COG2367	Beta-lactamase
IAR44_RS06105	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IAR44_RS06110	COG2814	Major facilitator Superfamily
IAR44_RS06115	COG1846	Transcriptional regulator
IAR44_RS06125	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IAR44_RS06130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAR44_RS06135	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAR44_RS06140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAR44_RS06140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAR44_RS06145	COG1447	Phosphotransferase system cellobiose-specific component IIA
IAR44_RS06155	COG1349	DNA-binding transcription factor activity
IAR44_RS06170	COG1285	pathogenesis
IAR44_RS06185	COG2205	protein histidine kinase activity
IAR44_RS06195	COG3383	formate dehydrogenase (NAD+) activity
IAR44_RS06200	COG2427	Protein of unknown function (DUF1641)
IAR44_RS06205	COG2124	cytochrome p450
IAR44_RS06210	COG1819	glycosyl
IAR44_RS06220	COG1587	Uroporphyrinogen-III synthase
IAR44_RS06225	COG0390	transport system, permease component
IAR44_RS06230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAR44_RS06235	COG0697	spore germination
IAR44_RS06240	COG4297	protein containing double-stranded beta helix domain
IAR44_RS06250	COG1252	NADH dehydrogenase
IAR44_RS06260	COG2211	Major facilitator Superfamily
IAR44_RS06265	COG1609	Transcriptional regulator
IAR44_RS06270	COG0246	Mannitol dehydrogenase
IAR44_RS06275	COG2721	sulfolactate sulfo-lyase activity
IAR44_RS06280	COG0745	RESPONSE REGULATOR receiver
IAR44_RS06285	COG2770	Histidine kinase
IAR44_RS06285	COG2205	protein histidine kinase activity
IAR44_RS06305	COG0730	response to heat
IAR44_RS06310	COG2318	DinB family
IAR44_RS06315	COG0457	Tetratricopeptide repeat
IAR44_RS06325	COG3409	Peptidoglycan-binding domain 1 protein
IAR44_RS06325	COG5632	N-Acetylmuramoyl-L-alanine amidase
IAR44_RS06325	COG1388	LysM domain
IAR44_RS06335	COG4195	phage-related replication protein
IAR44_RS06340	COG3546	catalase activity
IAR44_RS06345	COG2856	Zn peptidase
IAR44_RS06350	COG1396	sequence-specific DNA binding
IAR44_RS06360	COG1522	sequence-specific DNA binding
IAR44_RS06365	COG1484	DNA-dependent DNA replication
IAR44_RS06385	COG1595	DNA-templated transcription, initiation
IAR44_RS06390	COG3728	DNA packaging
IAR44_RS06390	COG5484	DNA packaging
IAR44_RS06395	COG1783	phage Terminase large subunit
IAR44_RS06400	COG5518	Phage portal protein
IAR44_RS06405	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IAR44_RS06410	COG4653	Phage capsid family
IAR44_RS06460	COG3953	SLT domain
IAR44_RS06460	COG3953	SLT domain
IAR44_RS06460	COG5412	phage tail tape measure protein
IAR44_RS06460	COG3953	SLT domain
IAR44_RS06460	COG5412	phage tail tape measure protein
IAR44_RS06460	COG5412	phage tail tape measure protein
IAR44_RS06465	COG1652	LysM domain
IAR44_RS06470	COG4193	domain, Protein
IAR44_RS06480	COG3628	GPW Gp25 family protein
IAR44_RS06485	COG3299	homolog of phage Mu protein gp47
IAR44_RS06490	COG3778	Protein conserved in bacteria
IAR44_RS06530	COG3409	Peptidoglycan-binding domain 1 protein
IAR44_RS06530	COG5632	N-Acetylmuramoyl-L-alanine amidase
IAR44_RS06545	COG0306	phosphate transporter
IAR44_RS06550	COG1392	Phosphate transport regulator
IAR44_RS06555	COG0531	amino acid
IAR44_RS06560	COG0346	lactoylglutathione lyase activity
IAR44_RS06565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAR44_RS06570	COG0463	Glycosyl transferase, family 2
IAR44_RS06580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAR44_RS06585	COG0477	Major facilitator Superfamily
IAR44_RS06590	COG2362	D-Aminopeptidase
IAR44_RS06595	COG0601	transmembrane transport
IAR44_RS06600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAR44_RS06605	COG0444	Belongs to the ABC transporter superfamily
IAR44_RS06610	COG4166	transmembrane transport
IAR44_RS06615	COG1619	proteins homologs of microcin C7 resistance protein MccF
IAR44_RS06620	COG4948	Mandelate Racemase Muconate Lactonizing
IAR44_RS06625	COG0791	NLP P60 protein
IAR44_RS06630	COG4608	Belongs to the ABC transporter superfamily
IAR44_RS06635	COG2706	6-phosphogluconolactonase activity
IAR44_RS06640	COG1834	amidinotransferase
IAR44_RS06645	COG1607	acyl-coa hydrolase
IAR44_RS06650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAR44_RS06655	COG2076	Multidrug Resistance protein
IAR44_RS06660	COG2076	Multidrug Resistance protein
IAR44_RS06665	COG0788	formyltetrahydrofolate deformylase activity
IAR44_RS06670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAR44_RS06680	COG1764	response to oxidative stress
IAR44_RS06685	COG1846	Transcriptional regulator
IAR44_RS06690	COG1764	response to oxidative stress
IAR44_RS06705	COG0463	Glycosyl transferase, family 2
IAR44_RS06705	COG0457	Tetratricopeptide repeat
IAR44_RS06715	COG2814	Major facilitator Superfamily
IAR44_RS06730	COG1404	Belongs to the peptidase S8 family
IAR44_RS06735	COG1366	Belongs to the anti-sigma-factor antagonist family
IAR44_RS06740	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAR44_RS06745	COG1122	ATPase activity
IAR44_RS06750	COG4721	ABC-type cobalt transport system, permease component
IAR44_RS06755	COG3858	chitin binding
IAR44_RS06755	COG1388	LysM domain
IAR44_RS06765	COG2239	Acts as a magnesium transporter
IAR44_RS06770	COG0789	Transcriptional regulator
IAR44_RS06785	COG1846	Transcriptional regulator
IAR44_RS06790	COG0726	polysaccharide deacetylase
IAR44_RS06795	COG1793	dna ligase
IAR44_RS06795	COG3285	dna ligase
IAR44_RS06800	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IAR44_RS06805	COG0586	Pfam SNARE associated Golgi protein
IAR44_RS06810	COG0861	Integral membrane protein TerC family
IAR44_RS06815	COG1191	sigma factor activity
IAR44_RS06845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAR44_RS06850	COG2323	membrane
IAR44_RS06860	COG3594	Acyltransferase
IAR44_RS06865	COG5002	protein histidine kinase activity
IAR44_RS06870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAR44_RS06885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAR44_RS06890	COG0436	Aminotransferase
IAR44_RS06920	COG3852	Histidine kinase
IAR44_RS06925	COG1846	Transcriptional regulator
IAR44_RS06930	COG1360	Flagellar Motor Protein
IAR44_RS06935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IAR44_RS06940	COG0542	response to heat
IAR44_RS06945	COG3949	Membrane
IAR44_RS06960	COG0720	synthase
IAR44_RS06965	COG0602	queuosine metabolic process
IAR44_RS06975	COG1733	regulation of RNA biosynthetic process
IAR44_RS06980	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS06990	COG1388	LysM domain
IAR44_RS06990	COG4641	Protein conserved in bacteria
IAR44_RS06995	COG1388	LysM domain
IAR44_RS07000	COG3858	chitin binding
IAR44_RS07010	COG4873	Protein conserved in bacteria
IAR44_RS07020	COG3773	Cell wall hydrolase
IAR44_RS07025	COG2244	polysaccharide biosynthetic process
IAR44_RS07030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAR44_RS07035	COG2217	Heavy metal translocating P-type atpase
IAR44_RS07040	COG0006	proline dipeptidase activity
IAR44_RS07045	COG1609	Transcriptional regulator
IAR44_RS07050	COG3711	transcriptional antiterminator
IAR44_RS07055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAR44_RS07055	COG2190	(PTS) system
IAR44_RS07055	COG1263	PTS System
IAR44_RS07060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAR44_RS07065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAR44_RS07075	COG1533	DNA photolyase activity
IAR44_RS07080	COG0840	transmembrane signaling receptor activity
IAR44_RS07085	COG2084	Dehydrogenase
IAR44_RS07090	COG2340	Cysteine-rich secretory protein family
IAR44_RS07095	COG0768	penicillin binding
IAR44_RS07100	COG4191	Histidine kinase
IAR44_RS07105	COG0436	Aminotransferase
IAR44_RS07115	COG0835	chemotaxis
IAR44_RS07115	COG0784	Response regulator, receiver
IAR44_RS07125	COG2814	Major facilitator Superfamily
IAR44_RS07130	COG1376	ErfK ybiS ycfS ynhG family protein
IAR44_RS07135	COG1408	metallophosphoesterase
IAR44_RS07140	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS07150	COG2200	EAL domain
IAR44_RS07155	COG4703	Protein of unknown function (DUF1797)
IAR44_RS07160	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
IAR44_RS07170	COG0517	IMP dehydrogenase activity
IAR44_RS07175	COG0583	DNA-binding transcription factor activity
IAR44_RS07180	COG0716	FMN binding
IAR44_RS07190	COG0716	FMN binding
IAR44_RS07215	COG0668	transmembrane transport
IAR44_RS07220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAR44_RS07240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAR44_RS07245	COG0303	'Molybdopterin
IAR44_RS07250	COG1763	Mo-molybdopterin cofactor biosynthetic process
IAR44_RS07255	COG0314	molybdopterin synthase activity
IAR44_RS07260	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IAR44_RS07270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAR44_RS07275	COG1136	(ABC) transporter
IAR44_RS07280	COG0577	efflux transmembrane transporter activity
IAR44_RS07285	COG1349	DNA-binding transcription factor activity
IAR44_RS07290	COG1105	Belongs to the carbohydrate kinase PfkB family
IAR44_RS07295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAR44_RS07295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAR44_RS07295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAR44_RS07300	COG0681	Belongs to the peptidase S26 family
IAR44_RS07310	COG0488	(ABC) transporter
IAR44_RS07315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAR44_RS07320	COG2309	aminopeptidase activity
IAR44_RS07330	COG1077	Cell shape determining protein MreB Mrl
IAR44_RS07335	COG2002	toxin-antitoxin pair type II binding
IAR44_RS07340	COG3852	Histidine kinase
IAR44_RS07345	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IAR44_RS07345	COG2105	PFAM AIG2 family protein
IAR44_RS07350	COG0569	domain protein
IAR44_RS07360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAR44_RS07370	COG0561	phosphatase activity
IAR44_RS07375	COG0242	peptide deformylase activity
IAR44_RS07385	COG0497	DNA recombination
IAR44_RS07395	COG3321	synthase
IAR44_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS07395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS07395	COG4221	oxidoreductase activity
IAR44_RS07400	COG4221	oxidoreductase activity
IAR44_RS07400	COG3321	synthase
IAR44_RS07400	COG0300	oxidoreductase activity
IAR44_RS07400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS07405	COG3321	synthase
IAR44_RS07405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS07405	COG4221	oxidoreductase activity
IAR44_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS07410	COG4221	oxidoreductase activity
IAR44_RS07410	COG0300	oxidoreductase activity
IAR44_RS07410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS07410	COG3321	synthase
IAR44_RS07415	COG0300	oxidoreductase activity
IAR44_RS07415	COG4221	oxidoreductase activity
IAR44_RS07415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS07415	COG3321	synthase
IAR44_RS07420	COG3321	synthase
IAR44_RS07420	COG4221	oxidoreductase activity
IAR44_RS07420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS07420	COG0300	oxidoreductase activity
IAR44_RS07425	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS07425	COG3321	synthase
IAR44_RS07425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS07425	COG4221	oxidoreductase activity
IAR44_RS07430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAR44_RS07435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAR44_RS07440	COG0022	dehydrogenase e1 component
IAR44_RS07445	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAR44_RS07450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAR44_RS07455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAR44_RS07470	COG1982	Orn Lys Arg decarboxylase major
IAR44_RS07490	COG0483	inositol monophosphate 1-phosphatase activity
IAR44_RS07500	COG3227	Zinc metalloprotease (Elastase)
IAR44_RS07515	COG1595	DNA-templated transcription, initiation
IAR44_RS07535	COG1217	gtp-binding protein TYPA
IAR44_RS07545	COG4896	Protein conserved in bacteria
IAR44_RS07555	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IAR44_RS07560	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IAR44_RS07565	COG2066	Belongs to the glutaminase family
IAR44_RS07575	COG0772	Belongs to the SEDS family
IAR44_RS07580	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IAR44_RS07595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAR44_RS07595	COG2010	Cytochrome c
IAR44_RS07600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAR44_RS07605	COG1845	cytochrome c oxidase, subunit III
IAR44_RS07610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IAR44_RS07615	COG3336	cytochrome c oxidase
IAR44_RS07625	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IAR44_RS07630	COG2340	Cysteine-rich secretory protein family
IAR44_RS07645	COG3679	Belongs to the UPF0342 family
IAR44_RS07655	COG0742	ribosomal rna small subunit methyltransferase
IAR44_RS07665	COG3314	Sporulation integral membrane protein YlbJ
IAR44_RS07670	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAR44_RS07675	COG3480	Lon protease (S16) C-terminal proteolytic domain
IAR44_RS07685	COG1399	metal-binding, possibly nucleic acid-binding protein
IAR44_RS07705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAR44_RS07725	COG4839	cell division protein FtsL
IAR44_RS07730	COG0768	penicillin binding
IAR44_RS07735	COG0768	penicillin binding
IAR44_RS07755	COG0772	Belongs to the SEDS family
IAR44_RS07770	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IAR44_RS07775	COG0849	cell division
IAR44_RS07780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAR44_RS07785	COG4412	M6 family metalloprotease domain protein
IAR44_RS07785	COG1404	Belongs to the peptidase S8 family
IAR44_RS07795	COG1191	sigma factor activity
IAR44_RS07800	COG1191	sigma factor activity
IAR44_RS07805	COG1119	ATPase activity
IAR44_RS07810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAR44_RS07815	COG1873	PFAM PRC-barrel domain
IAR44_RS07820	COG1496	oxidoreductase activity
IAR44_RS07825	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IAR44_RS07835	COG0762	integral membrane protein
IAR44_RS07840	COG2302	S4 RNA-binding domain
IAR44_RS07845	COG3599	regulation of cell shape
IAR44_RS07850	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAR44_RS07855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAR44_RS07865	COG0564	pseudouridine synthase activity
IAR44_RS07875	COG2233	PERMEase
IAR44_RS07885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IAR44_RS07890	COG0505	Belongs to the CarA family
IAR44_RS07895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAR44_RS07910	COG0284	orotidine-5'-phosphate decarboxylase activity
IAR44_RS07915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAR44_RS07925	COG0306	phosphate transporter
IAR44_RS07940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAR44_RS07945	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
IAR44_RS07950	COG1648	precorrin-2 dehydrogenase activity
IAR44_RS07960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IAR44_RS07965	COG1561	YicC-like family, N-terminal region
IAR44_RS07975	COG0194	GDP metabolic process
IAR44_RS07985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAR44_RS07990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAR44_RS07995	COG0242	peptide deformylase activity
IAR44_RS08005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAR44_RS08005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAR44_RS08015	COG0631	protein serine/threonine phosphatase activity
IAR44_RS08020	COG2815	serine threonine protein kinase
IAR44_RS08020	COG0515	serine threonine protein kinase
IAR44_RS08030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAR44_RS08035	COG1564	THIamine pyrophosphokinase
IAR44_RS08050	COG1302	Protein conserved in bacteria
IAR44_RS08055	COG1461	Dihydroxyacetone kinase
IAR44_RS08060	COG1760	l-serine dehydratase
IAR44_RS08065	COG1760	l-serine dehydratase
IAR44_RS08070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAR44_RS08085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IAR44_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS08105	COG1196	nuclear chromosome segregation
IAR44_RS08110	COG0552	protein localization to endoplasmic reticulum
IAR44_RS08125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAR44_RS08135	COG1837	Belongs to the UPF0109 family
IAR44_RS08160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IAR44_RS08175	COG2257	FlhB HrpN YscU SpaS Family
IAR44_RS08185	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAR44_RS08190	COG0758	DNA mediated transformation
IAR44_RS08195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAR44_RS08205	COG4974	Belongs to the 'phage' integrase family
IAR44_RS08225	COG1815	bacterial-type flagellum-dependent cell motility
IAR44_RS08230	COG1558	bacterial-type flagellum-dependent cell motility
IAR44_RS08235	COG1677	Flagellar hook-basal body complex protein FliE
IAR44_RS08240	COG1766	The M ring may be actively involved in energy transduction
IAR44_RS08245	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAR44_RS08250	COG1317	bacterial-type flagellum organization
IAR44_RS08255	COG1157	protein secretion by the type III secretion system
IAR44_RS08260	COG2882	bacterial-type flagellum organization
IAR44_RS08265	COG3334	PFAM MgtE intracellular
IAR44_RS08270	COG3144	bacterial-type flagellum assembly
IAR44_RS08275	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IAR44_RS08280	COG4786	Flagellar basal body rod
IAR44_RS08285	COG1582	Flagellar protein (FlbD)
IAR44_RS08290	COG1580	Controls the rotational direction of flagella during chemotaxis
IAR44_RS08295	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAR44_RS08300	COG1776	CheC inhibitor of MCP methylation
IAR44_RS08300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAR44_RS08305	COG2201	protein-glutamate methylesterase activity
IAR44_RS08310	COG3190	flagellar
IAR44_RS08315	COG1338	Plays a role in the flagellum-specific transport system
IAR44_RS08320	COG1987	bacterial-type flagellum assembly
IAR44_RS08325	COG1684	flagellar biosynthetic protein fliR
IAR44_RS08330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAR44_RS08335	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAR44_RS08340	COG1419	protein localization to endoplasmic reticulum
IAR44_RS08345	COG0455	bacterial-type flagellum organization
IAR44_RS08350	COG2201	protein-glutamate methylesterase activity
IAR44_RS08355	COG2198	Histidine kinase
IAR44_RS08355	COG0643	Histidine kinase
IAR44_RS08360	COG0835	chemotaxis
IAR44_RS08365	COG1776	CheC inhibitor of MCP methylation
IAR44_RS08375	COG1191	sigma factor activity
IAR44_RS08405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAR44_RS08410	COG4589	Belongs to the CDS family
IAR44_RS08420	COG0750	zinc metalloprotease
IAR44_RS08430	COG2176	DNA-directed DNA polymerase activity
IAR44_RS08440	COG0195	Participates in both transcription termination and antitermination
IAR44_RS08445	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IAR44_RS08450	COG1358	cellular component organization or biogenesis
IAR44_RS08460	COG1550	Protein conserved in bacteria
IAR44_RS08475	COG0196	riboflavin kinase activity
IAR44_RS08490	COG0726	polysaccharide deacetylase
IAR44_RS08495	COG0612	Peptidase, M16
IAR44_RS08500	COG1873	PFAM PRC-barrel domain
IAR44_RS08505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAR44_RS08510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAR44_RS08515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAR44_RS08520	COG0527	aspartate kinase activity
IAR44_RS08530	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAR44_RS08535	COG0740	serine-type endopeptidase activity
IAR44_RS08545	COG4980	gas vesicle protein
IAR44_RS08545	COG1674	ftsk spoiiie
IAR44_RS08550	COG2188	Transcriptional regulator
IAR44_RS08555	COG2814	Major facilitator Superfamily
IAR44_RS08560	COG1846	Transcriptional regulator
IAR44_RS08565	COG2409	Drug exporters of the RND superfamily
IAR44_RS08565	COG1033	growth of symbiont in host cell
IAR44_RS08570	COG0612	Peptidase, M16
IAR44_RS08575	COG0612	Peptidase, M16
IAR44_RS08580	COG0300	oxidoreductase activity
IAR44_RS08595	COG1426	Protein conserved in bacteria
IAR44_RS08600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAR44_RS08615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAR44_RS08625	COG1692	metallophosphoesterase
IAR44_RS08630	COG2359	stage V sporulation protein S
IAR44_RS08650	COG4550	Control of competence regulator ComK, YlbF/YmcA
IAR44_RS08670	COG0582	viral genome integration into host DNA
IAR44_RS08720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS08725	COG3425	synthase
IAR44_RS08730	COG1024	Enoyl-CoA hydratase
IAR44_RS08735	COG1024	Enoyl-CoA hydratase
IAR44_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS08740	COG0300	oxidoreductase activity
IAR44_RS08740	COG3321	synthase
IAR44_RS08740	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS08740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS08745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS08745	COG0300	oxidoreductase activity
IAR44_RS08745	COG4221	oxidoreductase activity
IAR44_RS08745	COG3321	synthase
IAR44_RS08750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS08750	COG3321	synthase
IAR44_RS08750	COG3321	synthase
IAR44_RS08750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS08750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS08750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAR44_RS08750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAR44_RS08750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS08755	COG4221	oxidoreductase activity
IAR44_RS08755	COG3321	synthase
IAR44_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS08755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS08760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS08760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAR44_RS08760	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IAR44_RS08760	COG3321	synthase
IAR44_RS08765	COG2124	cytochrome p450
IAR44_RS08770	COG3209	COG3209 Rhs family protein
IAR44_RS08775	COG3619	membrane
IAR44_RS08785	COG1404	Belongs to the peptidase S8 family
IAR44_RS08795	COG4195	phage-related replication protein
IAR44_RS08800	COG1764	response to oxidative stress
IAR44_RS08810	COG2076	Multidrug Resistance protein
IAR44_RS08850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAR44_RS08855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAR44_RS08860	COG4112	unkown
IAR44_RS08865	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAR44_RS08870	COG0464	growth
IAR44_RS08875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAR44_RS08880	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IAR44_RS08885	COG0789	Transcriptional regulator
IAR44_RS08890	COG0174	glutamine synthetase
IAR44_RS08905	COG1396	sequence-specific DNA binding
IAR44_RS08955	COG0305	Participates in initiation and elongation during chromosome replication
IAR44_RS08975	COG1595	DNA-templated transcription, initiation
IAR44_RS09030	COG0740	serine-type endopeptidase activity
IAR44_RS09070	COG3953	SLT domain
IAR44_RS09070	COG5280	Phage tail tape measure protein TP901
IAR44_RS09130	COG5444	nuclease activity
IAR44_RS09135	COG0457	Tetratricopeptide repeat
IAR44_RS09150	COG4282	regulation of fungal-type cell wall biogenesis
IAR44_RS09155	COG5444	nuclease activity
IAR44_RS09175	COG2211	Major facilitator Superfamily
IAR44_RS09180	COG3507	Belongs to the glycosyl hydrolase 43 family
IAR44_RS09195	COG1070	Carbohydrate kinase
IAR44_RS09200	COG0574	Belongs to the PEP-utilizing enzyme family
IAR44_RS09200	COG3848	Pyruvate phosphate dikinase
IAR44_RS09220	COG1064	alcohol dehydrogenase
IAR44_RS09235	COG0456	acetyltransferase
IAR44_RS09260	COG3397	chitin binding
IAR44_RS09270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAR44_RS09285	COG5434	Belongs to the glycosyl hydrolase 28 family
IAR44_RS09295	COG4195	phage-related replication protein
IAR44_RS09330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IAR44_RS09340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAR44_RS09360	COG0785	Cytochrome C biogenesis protein
IAR44_RS09365	COG2201	protein-glutamate methylesterase activity
IAR44_RS09370	COG4846	Membrane protein involved in cytochrome C biogenesis
IAR44_RS09380	COG0071	Belongs to the small heat shock protein (HSP20) family
IAR44_RS09395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAR44_RS09400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAR44_RS09420	COG0824	Thioesterase
IAR44_RS09430	COG4841	protein insertion into membrane
IAR44_RS09440	COG1832	CoA-binding protein
IAR44_RS09445	COG0187	DNA topoisomerase II activity
IAR44_RS09450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAR44_RS09465	COG1115	amino acid carrier protein
IAR44_RS09475	COG1063	alcohol dehydrogenase
IAR44_RS09480	COG0800	Aldolase
IAR44_RS09485	COG1312	Catalyzes the dehydration of D-mannonate
IAR44_RS09490	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS09495	COG1609	Transcriptional regulator
IAR44_RS09500	COG2271	Major facilitator Superfamily
IAR44_RS09570	COG0577	efflux transmembrane transporter activity
IAR44_RS09570	COG1136	(ABC) transporter
IAR44_RS09600	COG2205	protein histidine kinase activity
IAR44_RS09605	COG0745	RESPONSE REGULATOR receiver
IAR44_RS09615	COG3507	Belongs to the glycosyl hydrolase 43 family
IAR44_RS09645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAR44_RS09650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAR44_RS09655	COG2610	gluconate transmembrane transporter activity
IAR44_RS09660	COG2124	cytochrome p450
IAR44_RS09680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAR44_RS09690	COG2246	polysaccharide biosynthetic process
IAR44_RS09695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAR44_RS09700	COG0586	Pfam SNARE associated Golgi protein
IAR44_RS09705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAR44_RS09710	COG1024	Enoyl-CoA hydratase
IAR44_RS09715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAR44_RS09720	COG0511	ligase activity, forming carbon-carbon bonds
IAR44_RS09725	COG0439	Biotin carboxylase
IAR44_RS09730	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS09735	COG1960	acyl-CoA dehydrogenase activity
IAR44_RS09740	COG1649	PFAM Uncharacterised BCR, COG1649
IAR44_RS09750	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IAR44_RS09750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS09755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS09760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS09765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS09770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS09775	COG2027	D-alanyl-D-alanine carboxypeptidase
IAR44_RS09780	COG2017	converts alpha-aldose to the beta-anomer
IAR44_RS09785	COG0534	Mate efflux family protein
IAR44_RS09800	COG0582	viral genome integration into host DNA
IAR44_RS09805	COG0166	Belongs to the GPI family
IAR44_RS09810	COG0405	Gamma-glutamyltransferase
IAR44_RS09815	COG2814	Major facilitator Superfamily
IAR44_RS09820	COG0640	Transcriptional regulator
IAR44_RS09825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAR44_RS09835	COG0604	alcohol dehydrogenase
IAR44_RS09840	COG0493	'glutamate synthase
IAR44_RS09845	COG0069	glutamate synthase activity
IAR44_RS09845	COG0070	glutamate synthase
IAR44_RS09845	COG0067	glutamate synthase
IAR44_RS09850	COG0583	DNA-binding transcription factor activity
IAR44_RS09855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAR44_RS09875	COG0300	oxidoreductase activity
IAR44_RS09880	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IAR44_RS09890	COG2814	Major facilitator Superfamily
IAR44_RS09895	COG1070	Carbohydrate kinase
IAR44_RS09900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAR44_RS09905	COG0243	molybdopterin cofactor binding
IAR44_RS09940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAR44_RS09945	COG0662	Cupin 2, conserved barrel domain protein
IAR44_RS09945	COG2207	Transcriptional regulator
IAR44_RS09950	COG1309	transcriptional regulator
IAR44_RS09955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAR44_RS09965	COG0640	Transcriptional regulator
IAR44_RS09970	COG0741	lytic transglycosylase activity
IAR44_RS09975	COG2322	membrane
IAR44_RS09990	COG1619	proteins homologs of microcin C7 resistance protein MccF
IAR44_RS10000	COG3584	3D domain protein
IAR44_RS10000	COG1388	LysM domain
IAR44_RS10005	COG0514	ATP-dependent DNA helicase (RecQ)
IAR44_RS10015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAR44_RS10020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAR44_RS10035	COG0071	Belongs to the small heat shock protein (HSP20) family
IAR44_RS10065	COG1012	belongs to the aldehyde dehydrogenase family
IAR44_RS10070	COG1657	PFAM Prenyltransferase squalene oxidase
IAR44_RS10075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAR44_RS10080	COG0733	neurotransmitter:sodium symporter activity
IAR44_RS10085	COG0385	Bile acid
IAR44_RS10090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAR44_RS10095	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAR44_RS10105	COG4548	von Willebrand factor, type A
IAR44_RS10110	COG0714	Associated with various cellular activities
IAR44_RS10115	COG2032	superoxide dismutase activity
IAR44_RS10120	COG0791	NLP P60 protein
IAR44_RS10120	COG1388	LysM domain
IAR44_RS10125	COG1819	glycosyl
IAR44_RS10130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IAR44_RS10135	COG0534	Mate efflux family protein
IAR44_RS10140	COG1366	Belongs to the anti-sigma-factor antagonist family
IAR44_RS10145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAR44_RS10150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAR44_RS10160	COG2962	Rard protein
IAR44_RS10175	COG1942	4-Oxalocrotonate Tautomerase
IAR44_RS10185	COG1733	regulation of RNA biosynthetic process
IAR44_RS10190	COG0778	Nitroreductase
IAR44_RS10195	COG0400	carboxylic ester hydrolase activity
IAR44_RS10200	COG0346	lactoylglutathione lyase activity
IAR44_RS10210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAR44_RS10220	COG2723	6-phospho-beta-galactosidase activity
IAR44_RS10225	COG2188	Transcriptional regulator
IAR44_RS10230	COG3409	Peptidoglycan-binding domain 1 protein
IAR44_RS10230	COG0793	Belongs to the peptidase S41A family
IAR44_RS10235	COG2226	methyltransferase
IAR44_RS10245	COG1876	peptidase activity
IAR44_RS10265	COG0671	phosphoesterase, PA-phosphatase related
IAR44_RS10300	COG1509	lysine 2,3-aminomutase activity
IAR44_RS10305	COG0456	acetyltransferase
IAR44_RS10310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAR44_RS10315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAR44_RS10320	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAR44_RS10325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAR44_RS10330	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IAR44_RS10340	COG0456	acetyltransferase
IAR44_RS10345	COG0463	Glycosyl transferase, family 2
IAR44_RS10360	COG4641	Protein conserved in bacteria
IAR44_RS10370	COG1086	Polysaccharide biosynthesis protein
IAR44_RS10415	COG1388	LysM domain
IAR44_RS10420	COG0457	Tetratricopeptide repeat
IAR44_RS10440	COG5444	nuclease activity
IAR44_RS10445	COG4282	regulation of fungal-type cell wall biogenesis
IAR44_RS10450	COG1525	nuclease
IAR44_RS10455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IAR44_RS10475	COG1846	Transcriptional regulator
IAR44_RS10480	COG4698	Protein conserved in bacteria
IAR44_RS10485	COG2755	lipolytic protein G-D-S-L family
IAR44_RS10490	COG1999	signal sequence binding
IAR44_RS10500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAR44_RS10505	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IAR44_RS10510	COG1272	protein, Hemolysin III
IAR44_RS10515	COG0204	Acyl-transferase
IAR44_RS10520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAR44_RS10535	COG2521	methyltransferase
IAR44_RS10535	COG2136	Putative SAM-dependent methyltransferase
IAR44_RS10550	COG1413	lyase activity
IAR44_RS10555	COG1418	mRNA catabolic process
IAR44_RS10560	COG0386	Belongs to the glutathione peroxidase family
IAR44_RS10570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAR44_RS10580	COG1278	Cold shock
IAR44_RS10600	COG0328	RNA-DNA hybrid ribonuclease activity
IAR44_RS10605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IAR44_RS10610	COG0328	RNA-DNA hybrid ribonuclease activity
IAR44_RS10620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAR44_RS10635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IAR44_RS10645	COG1755	Isoprenylcysteine carboxyl methyltransferase
IAR44_RS10650	COG3424	synthase
IAR44_RS10675	COG1335	isochorismatase
IAR44_RS10685	COG2233	PERMEase
IAR44_RS10695	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IAR44_RS10700	COG1199	ATP-dependent helicase activity
IAR44_RS10715	COG0116	Belongs to the methyltransferase superfamily
IAR44_RS10745	COG3359	exonuclease
IAR44_RS10750	COG1111	helicase
IAR44_RS10750	COG1205	dead DEAH box helicase
IAR44_RS10755	COG2190	(PTS) system
IAR44_RS10760	COG0071	Belongs to the small heat shock protein (HSP20) family
IAR44_RS10800	COG4499	WXG100 protein secretion system (Wss), protein YukC
IAR44_RS10800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAR44_RS10815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAR44_RS10820	COG3935	DnaD domain protein
IAR44_RS10830	COG0436	Aminotransferase
IAR44_RS10835	COG5353	protein conserved in bacteria
IAR44_RS10845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAR44_RS10845	COG1199	ATP-dependent helicase activity
IAR44_RS10875	COG0438	transferase activity, transferring glycosyl groups
IAR44_RS10880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAR44_RS10895	COG1694	Mazg nucleotide pyrophosphohydrolase
IAR44_RS10900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAR44_RS10905	COG2140	Oxalate decarboxylase
IAR44_RS10915	COG4347	Protein of unknown function (DUF1405)
IAR44_RS10920	COG2010	Cytochrome c
IAR44_RS10920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IAR44_RS10925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IAR44_RS10930	COG0723	plastoquinol--plastocyanin reductase activity
IAR44_RS10945	COG0457	Tetratricopeptide repeat
IAR44_RS10955	COG0287	Prephenate dehydrogenase
IAR44_RS10990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAR44_RS10995	COG4401	Chorismate mutase type I
IAR44_RS11010	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IAR44_RS11015	COG0105	UTP biosynthetic process
IAR44_RS11020	COG0142	geranyltranstransferase activity
IAR44_RS11030	COG0142	geranyltranstransferase activity
IAR44_RS11045	COG0776	regulation of translation
IAR44_RS11050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IAR44_RS11090	COG0539	negative regulation of cytoplasmic translation
IAR44_RS11105	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IAR44_RS11110	COG2959	enzyme of heme biosynthesis
IAR44_RS11115	COG3773	Cell wall hydrolase
IAR44_RS11115	COG3409	Peptidoglycan-binding domain 1 protein
IAR44_RS11120	COG2339	peptidase activity
IAR44_RS11125	COG0492	ferredoxin-NADP+ reductase activity
IAR44_RS11130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAR44_RS11135	COG4862	establishment of competence for transformation
IAR44_RS11140	COG1408	metallophosphoesterase
IAR44_RS11150	COG1388	LysM domain
IAR44_RS11155	COG1266	CAAX protease self-immunity
IAR44_RS11160	COG0514	ATP-dependent DNA helicase (RecQ)
IAR44_RS11165	COG4955	Helix-turn-helix domain
IAR44_RS11170	COG1141	Ferredoxin
IAR44_RS11175	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IAR44_RS11180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAR44_RS11190	COG1595	DNA-templated transcription, initiation
IAR44_RS11195	COG5002	protein histidine kinase activity
IAR44_RS11200	COG0745	RESPONSE REGULATOR receiver
IAR44_RS11205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IAR44_RS11210	COG1333	cytochrome c biogenesis protein
IAR44_RS11215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAR44_RS11220	COG1187	pseudouridine synthase activity
IAR44_RS11225	COG0700	Nucleoside recognition
IAR44_RS11230	COG2715	membrane protein required for spore maturation
IAR44_RS11235	COG1686	Belongs to the peptidase S11 family
IAR44_RS11260	COG1547	Domain of unknown function (DUF309)
IAR44_RS11265	COG0456	acetyltransferase
IAR44_RS11280	COG0307	riboflavin synthase, alpha
IAR44_RS11285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAR44_RS11285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAR44_RS11295	COG0681	Belongs to the peptidase S26 family
IAR44_RS11305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAR44_RS11310	COG4086	secreted protein
IAR44_RS11315	COG0019	diaminopimelate decarboxylase activity
IAR44_RS11320	COG0697	spore germination
IAR44_RS11335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAR44_RS11355	COG1191	sigma factor activity
IAR44_RS11365	COG1366	Belongs to the anti-sigma-factor antagonist family
IAR44_RS11370	COG1686	Belongs to the peptidase S11 family
IAR44_RS11375	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IAR44_RS11380	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IAR44_RS11385	COG4974	Belongs to the 'phage' integrase family
IAR44_RS11395	COG0735	belongs to the Fur family
IAR44_RS11400	COG1300	Membrane
IAR44_RS11415	COG0281	malic enzyme
IAR44_RS11420	COG1757	Na H antiporter
IAR44_RS11425	COG1027	Aspartate ammonia-lyase
IAR44_RS11430	COG0252	asparaginase activity
IAR44_RS11435	COG1396	sequence-specific DNA binding
IAR44_RS11440	COG1379	DNA repair
IAR44_RS11445	COG0494	nUDIX hydrolase
IAR44_RS11455	COG0667	Aldo Keto reductase
IAR44_RS11475	COG4918	Iron-sulphur cluster biosynthesis
IAR44_RS11480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAR44_RS11480	COG0456	acetyltransferase
IAR44_RS11485	COG2329	Antibiotic biosynthesis monooxygenase
IAR44_RS11490	COG0456	acetyltransferase
IAR44_RS11495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAR44_RS11510	COG0628	permease
IAR44_RS11520	COG0346	lactoylglutathione lyase activity
IAR44_RS11530	COG3048	D-serine ammonia-lyase activity
IAR44_RS11535	COG0300	oxidoreductase activity
IAR44_RS11540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAR44_RS11545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAR44_RS11550	COG1024	Enoyl-CoA hydratase
IAR44_RS11555	COG3425	synthase
IAR44_RS11560	COG2124	cytochrome p450
IAR44_RS11565	COG3321	synthase
IAR44_RS11565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS11565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS11565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAR44_RS11570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS11570	COG3321	synthase
IAR44_RS11570	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS11570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS11570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAR44_RS11575	COG0300	oxidoreductase activity
IAR44_RS11575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS11575	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS11575	COG3321	synthase
IAR44_RS11580	COG0300	oxidoreductase activity
IAR44_RS11580	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS11580	COG3321	synthase
IAR44_RS11580	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS11580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS11585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS11585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAR44_RS11585	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS11585	COG3321	synthase
IAR44_RS11585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS11590	COG3321	synthase
IAR44_RS11590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS11590	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS11590	COG0300	oxidoreductase activity
IAR44_RS11595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAR44_RS11595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS11595	COG3321	synthase
IAR44_RS11595	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS11595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAR44_RS11600	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS11605	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS11620	COG2070	2-Nitropropane dioxygenase
IAR44_RS11620	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IAR44_RS11625	COG0250	Participates in transcription elongation, termination and antitermination
IAR44_RS11645	COG0596	Alpha beta hydrolase
IAR44_RS11660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IAR44_RS11665	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAR44_RS11680	COG0706	membrane insertase activity
IAR44_RS11685	COG2195	Cleaves the N-terminal amino acid of tripeptides
IAR44_RS11690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAR44_RS11695	COG0346	lactoylglutathione lyase activity
IAR44_RS11705	COG1376	ErfK ybiS ycfS ynhG family protein
IAR44_RS11710	COG4129	membrane
IAR44_RS11715	COG1126	abc transporter atp-binding protein
IAR44_RS11720	COG0765	amino acid transport
IAR44_RS11725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAR44_RS11735	COG1597	lipid kinase activity
IAR44_RS11740	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAR44_RS11745	COG0022	dehydrogenase e1 component
IAR44_RS11750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAR44_RS11755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAR44_RS11760	COG3426	butyrate kinase activity
IAR44_RS11765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAR44_RS11770	COG0280	phosphate acetyltransferase
IAR44_RS11775	COG3829	transcription factor binding
IAR44_RS11775	COG3290	protein histidine kinase activity
IAR44_RS11785	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IAR44_RS11790	COG2079	MmgE PrpD family protein
IAR44_RS11795	COG0372	Belongs to the citrate synthase family
IAR44_RS11800	COG1960	acyl-CoA dehydrogenase activity
IAR44_RS11805	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAR44_RS11810	COG0183	Belongs to the thiolase family
IAR44_RS11815	COG0584	glycerophosphoryl diester phosphodiesterase
IAR44_RS11820	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAR44_RS11845	COG1902	pentaerythritol trinitrate reductase activity
IAR44_RS11860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAR44_RS11865	COG0745	RESPONSE REGULATOR receiver
IAR44_RS11870	COG0750	zinc metalloprotease
IAR44_RS11875	COG0497	DNA recombination
IAR44_RS11885	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IAR44_RS11895	COG0142	geranyltranstransferase activity
IAR44_RS11905	COG1570	exodeoxyribonuclease VII activity
IAR44_RS11920	COG1302	Protein conserved in bacteria
IAR44_RS11925	COG0439	Biotin carboxylase
IAR44_RS11930	COG0511	ligase activity, forming carbon-carbon bonds
IAR44_RS11970	COG3854	ATPases associated with a variety of cellular activities
IAR44_RS11985	COG0006	proline dipeptidase activity
IAR44_RS11995	COG3872	metal-dependent enzyme
IAR44_RS12005	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAR44_RS12020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAR44_RS12040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAR44_RS12055	COG1396	sequence-specific DNA binding
IAR44_RS12065	COG0681	Belongs to the peptidase S26 family
IAR44_RS12090	COG4940	Competence protein ComGF
IAR44_RS12100	COG4970	Tfp pilus assembly protein FimT
IAR44_RS12105	COG4537	Required for transformation and DNA binding
IAR44_RS12110	COG1459	type II secretion system
IAR44_RS12115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAR44_RS12120	COG0598	Magnesium transport protein CorA
IAR44_RS12125	COG1253	flavin adenine dinucleotide binding
IAR44_RS12130	COG1366	Belongs to the anti-sigma-factor antagonist family
IAR44_RS12140	COG1393	Belongs to the ArsC family
IAR44_RS12150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAR44_RS12165	COG0011	TIGRFAM Protein of
IAR44_RS12175	COG2866	Carboxypeptidase
IAR44_RS12180	COG1940	carbohydrate kinase activity
IAR44_RS12185	COG4483	Protein conserved in bacteria
IAR44_RS12190	COG1757	Na H antiporter
IAR44_RS12200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAR44_RS12215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAR44_RS12220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAR44_RS12225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAR44_RS12230	COG0581	inorganic phosphate transmembrane transporter activity
IAR44_RS12235	COG0573	inorganic phosphate transmembrane transporter activity
IAR44_RS12240	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAR44_RS12245	COG0768	penicillin binding
IAR44_RS12250	COG0477	Major facilitator Superfamily
IAR44_RS12255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAR44_RS12260	COG2839	Protein conserved in bacteria
IAR44_RS12265	COG5521	maltodextrose utilization protein MalA
IAR44_RS12270	COG1388	LysM domain
IAR44_RS12280	COG4709	membrane
IAR44_RS12285	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
IAR44_RS12290	COG0735	belongs to the Fur family
IAR44_RS12295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAR44_RS12310	COG0513	Belongs to the DEAD box helicase family
IAR44_RS12325	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAR44_RS12330	COG2384	SAM-dependent methyltransferase
IAR44_RS12335	COG2010	Cytochrome c
IAR44_RS12340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAR44_RS12345	COG0358	DNA primase activity
IAR44_RS12360	COG0517	IMP dehydrogenase activity
IAR44_RS12365	COG0751	glycine-tRNA ligase activity
IAR44_RS12385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAR44_RS12390	COG0295	cytidine deaminase activity
IAR44_RS12395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IAR44_RS12405	COG1480	7TM receptor with intracellular HD hydrolase
IAR44_RS12410	COG1702	phosphate starvation-inducible protein PhoH
IAR44_RS12415	COG0561	phosphatase activity
IAR44_RS12430	COG4864	UPF0365 protein
IAR44_RS12435	COG1030	water channel activity
IAR44_RS12440	COG1610	YqeY-like protein
IAR44_RS12450	COG1283	sodium-dependent phosphate transmembrane transporter activity
IAR44_RS12460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAR44_RS12465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAR44_RS12495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAR44_RS12510	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAR44_RS12525	COG1466	dna polymerase III delta subunit
IAR44_RS12540	COG2333	competence protein COMEC
IAR44_RS12540	COG0658	competence protein
IAR44_RS12545	COG2131	deaminase
IAR44_RS12550	COG1596	polysaccharide export
IAR44_RS12550	COG1555	photosystem II stabilization
IAR44_RS12555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAR44_RS12560	COG2226	methyltransferase
IAR44_RS12565	COG0799	negative regulation of ribosome biogenesis
IAR44_RS12570	COG1713	HD superfamily hydrolase involved in NAD metabolism
IAR44_RS12580	COG1534	Rna-binding protein
IAR44_RS12585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAR44_RS12590	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IAR44_RS12595	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IAR44_RS12605	COG2755	lipolytic protein G-D-S-L family
IAR44_RS12615	COG0398	Pfam SNARE associated Golgi protein
IAR44_RS12650	COG0642	Histidine kinase
IAR44_RS12650	COG5002	protein histidine kinase activity
IAR44_RS12655	COG0745	RESPONSE REGULATOR receiver
IAR44_RS12660	COG2311	Membrane
IAR44_RS12670	COG0454	-acetyltransferase
IAR44_RS12675	COG0563	adenylate kinase activity
IAR44_RS12705	COG5444	nuclease activity
IAR44_RS12735	COG0456	acetyltransferase
IAR44_RS12740	COG2318	DinB family
IAR44_RS12750	COG0561	phosphatase activity
IAR44_RS12755	COG0561	phosphatase activity
IAR44_RS12765	COG1482	cell wall glycoprotein biosynthetic process
IAR44_RS12770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAR44_RS12770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAR44_RS12770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAR44_RS12775	COG3711	transcriptional antiterminator
IAR44_RS12775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAR44_RS12785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAR44_RS12790	COG0583	DNA-binding transcription factor activity
IAR44_RS12795	COG2814	Major facilitator Superfamily
IAR44_RS12800	COG2124	cytochrome p450
IAR44_RS12800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IAR44_RS12805	COG1309	transcriptional regulator
IAR44_RS12810	COG2226	methyltransferase
IAR44_RS12825	COG2116	formate transmembrane transporter activity
IAR44_RS12830	COG5609	conserved protein (DUF2294)
IAR44_RS12835	COG3383	formate dehydrogenase (NAD+) activity
IAR44_RS12840	COG2427	Protein of unknown function (DUF1641)
IAR44_RS12850	COG0626	cystathionine gamma-synthase activity
IAR44_RS12855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAR44_RS12880	COG0768	penicillin binding
IAR44_RS12895	COG0826	peptidase U32
IAR44_RS12900	COG0826	peptidase U32
IAR44_RS12905	COG4122	O-methyltransferase activity
IAR44_RS12910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAR44_RS12925	COG4472	Bacterial protein of unknown function (DUF965)
IAR44_RS12935	COG0628	permease
IAR44_RS12940	COG1126	abc transporter atp-binding protein
IAR44_RS12945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAR44_RS12950	COG0765	amino acid transport
IAR44_RS12955	COG0765	amino acid transport
IAR44_RS12970	COG3881	PFAM PRC-barrel domain
IAR44_RS12975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAR44_RS12980	COG0457	Tetratricopeptide repeat
IAR44_RS12990	COG1104	cysteine desulfurase activity
IAR44_RS12995	COG1959	2 iron, 2 sulfur cluster binding
IAR44_RS13000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAR44_RS13005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IAR44_RS13030	COG3103	Sh3 type 3 domain protein
IAR44_RS13030	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAR44_RS13030	COG4991	sh3 domain protein
IAR44_RS13040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAR44_RS13050	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IAR44_RS13050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IAR44_RS13055	COG5416	Lipopolysaccharide assembly protein A domain
IAR44_RS13060	COG0490	domain, Protein
IAR44_RS13065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAR44_RS13065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAR44_RS13075	COG2244	polysaccharide biosynthetic process
IAR44_RS13080	COG2323	membrane
IAR44_RS13090	COG1862	Preprotein translocase
IAR44_RS13135	COG1388	LysM domain
IAR44_RS13145	COG0157	Belongs to the NadC ModD family
IAR44_RS13150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IAR44_RS13155	COG1104	cysteine desulfurase activity
IAR44_RS13160	COG1827	regulation of RNA biosynthetic process
IAR44_RS13165	COG0077	Prephenate dehydratase
IAR44_RS13180	COG3290	protein histidine kinase activity
IAR44_RS13185	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IAR44_RS13190	COG2868	ribosomal protein
IAR44_RS13200	COG1994	Peptidase M50
IAR44_RS13205	COG0739	heme binding
IAR44_RS13210	COG2894	cell division
IAR44_RS13220	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IAR44_RS13230	COG1077	Cell shape determining protein MreB Mrl
IAR44_RS13250	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IAR44_RS13255	COG0285	dihydrofolate synthase activity
IAR44_RS13260	COG0525	valine-tRNA ligase activity
IAR44_RS13270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IAR44_RS13275	COG1388	LysM domain
IAR44_RS13285	COG0113	porphobilinogen synthase activity
IAR44_RS13290	COG1587	Uroporphyrinogen-III synthase
IAR44_RS13300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IAR44_RS13320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IAR44_RS13325	COG0470	DNA polymerase III
IAR44_RS13325	COG1067	ATP-dependent peptidase activity
IAR44_RS13340	COG1477	protein flavinylation
IAR44_RS13340	COG0457	Tetratricopeptide repeat
IAR44_RS13355	COG0473	3-isopropylmalate dehydrogenase activity
IAR44_RS13370	COG0440	acetolactate synthase activity
IAR44_RS13375	COG0028	Belongs to the TPP enzyme family
IAR44_RS13405	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IAR44_RS13420	COG0622	Phosphoesterase
IAR44_RS13425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IAR44_RS13435	COG5401	PFAM Sporulation and spore germination
IAR44_RS13445	COG1846	Transcriptional regulator
IAR44_RS13450	COG2197	response regulator
IAR44_RS13455	COG0824	Thioesterase
IAR44_RS13460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAR44_RS13465	COG1053	succinate dehydrogenase
IAR44_RS13470	COG2009	succinate dehydrogenase
IAR44_RS13475	COG1719	4-vinyl reductase, 4VR
IAR44_RS13480	COG0527	aspartate kinase activity
IAR44_RS13490	COG3118	belongs to the thioredoxin family
IAR44_RS13495	COG3534	alpha-L-arabinofuranosidase
IAR44_RS13500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IAR44_RS13505	COG2086	electron transfer activity
IAR44_RS13510	COG1024	Enoyl-CoA hydratase
IAR44_RS13515	COG1309	transcriptional regulator
IAR44_RS13520	COG0318	PFAM AMP-dependent synthetase and ligase
IAR44_RS13530	COG3766	membrane
IAR44_RS13540	COG1796	DNA polymerase
IAR44_RS13540	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IAR44_RS13545	COG1286	toxin biosynthetic process
IAR44_RS13560	COG0072	phenylalanine-tRNA ligase activity
IAR44_RS13560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAR44_RS13565	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAR44_RS13570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAR44_RS13580	COG3835	regulator
IAR44_RS13585	COG0277	FAD linked oxidase domain protein
IAR44_RS13590	COG0247	lactate metabolic process
IAR44_RS13595	COG1966	Carbon starvation protein
IAR44_RS13600	COG3534	alpha-L-arabinofuranosidase
IAR44_RS13605	COG0395	ABC-type sugar transport system, permease component
IAR44_RS13610	COG1175	transmembrane transport
IAR44_RS13615	COG1653	transport
IAR44_RS13625	COG0647	UMP catabolic process
IAR44_RS13630	COG0235	Class ii aldolase
IAR44_RS13635	COG1069	ribulokinase activity
IAR44_RS13640	COG2160	L-arabinose isomerase activity
IAR44_RS13645	COG3507	Belongs to the glycosyl hydrolase 43 family
IAR44_RS13650	COG1363	Peptidase, m42
IAR44_RS13660	COG3326	Membrane
IAR44_RS13665	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IAR44_RS13675	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAR44_RS13680	COG1346	cytolysis
IAR44_RS13685	COG1380	Effector of murein hydrolase LrgA
IAR44_RS13690	COG3279	Response regulator of the LytR AlgR family
IAR44_RS13695	COG3275	phosphorelay sensor kinase activity
IAR44_RS13700	COG1011	Hydrolase
IAR44_RS13715	COG0398	Pfam SNARE associated Golgi protein
IAR44_RS13720	COG1484	DNA-dependent DNA replication
IAR44_RS13725	COG3611	Membrane attachment protein
IAR44_RS13740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAR44_RS13745	COG1733	regulation of RNA biosynthetic process
IAR44_RS13750	COG2814	Major facilitator Superfamily
IAR44_RS13755	COG0656	L-ascorbic acid biosynthetic process
IAR44_RS13760	COG0237	dephospho-CoA kinase activity
IAR44_RS13765	COG1971	Probably functions as a manganese efflux pump
IAR44_RS13770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IAR44_RS13775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAR44_RS13775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAR44_RS13780	COG5002	protein histidine kinase activity
IAR44_RS13785	COG0745	RESPONSE REGULATOR receiver
IAR44_RS13795	COG0538	isocitrate dehydrogenase activity
IAR44_RS13800	COG0372	Belongs to the citrate synthase family
IAR44_RS13815	COG0628	permease
IAR44_RS13820	COG3030	protein affecting phage T7 exclusion by the F plasmid
IAR44_RS13825	COG0469	pyruvate kinase activity
IAR44_RS13845	COG0281	malic enzyme
IAR44_RS13850	COG0587	DNA-directed DNA polymerase activity
IAR44_RS13870	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IAR44_RS13880	COG4109	DRTGG domain
IAR44_RS13890	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS13905	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAR44_RS13915	COG0827	DNA restriction-modification system
IAR44_RS13920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IAR44_RS13925	COG3874	Sporulation protein YtfJ
IAR44_RS13935	COG1714	RDD family
IAR44_RS13940	COG0616	signal peptide processing
IAR44_RS13945	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAR44_RS13950	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IAR44_RS13955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAR44_RS13970	COG1104	cysteine desulfurase activity
IAR44_RS13975	COG1114	Component of the transport system for branched-chain amino acids
IAR44_RS13985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IAR44_RS13990	COG1309	transcriptional regulator
IAR44_RS13995	COG1956	GAF domain-containing protein
IAR44_RS14000	COG2203	Gaf domain
IAR44_RS14000	COG2199	diguanylate cyclase activity
IAR44_RS14010	COG1012	belongs to the aldehyde dehydrogenase family
IAR44_RS14015	COG4282	regulation of fungal-type cell wall biogenesis
IAR44_RS14065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAR44_RS14065	COG1017	nitric oxide dioxygenase activity
IAR44_RS14080	COG0693	protein deglycase activity
IAR44_RS14095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAR44_RS14100	COG1378	Sugar-specific transcriptional regulator TrmB
IAR44_RS14120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAR44_RS14125	COG0454	-acetyltransferase
IAR44_RS14130	COG0517	IMP dehydrogenase activity
IAR44_RS14135	COG0123	including yeast histone deacetylase and acetoin utilization protein
IAR44_RS14140	COG1360	Flagellar Motor Protein
IAR44_RS14145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IAR44_RS14150	COG1609	Transcriptional regulator
IAR44_RS14155	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IAR44_RS14155	COG1605	Chorismate mutase
IAR44_RS14160	COG3118	belongs to the thioredoxin family
IAR44_RS14165	COG4980	gas vesicle protein
IAR44_RS14170	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IAR44_RS14180	COG1674	ftsk spoiiie
IAR44_RS14185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAR44_RS14195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAR44_RS14205	COG1363	Peptidase, m42
IAR44_RS14210	COG5584	Small secreted protein
IAR44_RS14215	COG0281	malic enzyme
IAR44_RS14220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAR44_RS14235	COG0510	thiamine kinase activity
IAR44_RS14240	COG1597	lipid kinase activity
IAR44_RS14250	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IAR44_RS14255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAR44_RS14260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAR44_RS14265	COG2252	PERMEase
IAR44_RS14270	COG4473	ABC transporter
IAR44_RS14275	COG1131	(ABC) transporter
IAR44_RS14280	COG1349	DNA-binding transcription factor activity
IAR44_RS14285	COG1187	pseudouridine synthase activity
IAR44_RS14290	COG2244	polysaccharide biosynthetic process
IAR44_RS14295	COG2081	HI0933 family
IAR44_RS14300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAR44_RS14310	COG1609	Transcriptional regulator
IAR44_RS14315	COG1653	transport
IAR44_RS14320	COG1175	transmembrane transport
IAR44_RS14325	COG0395	ABC-type sugar transport system, permease component
IAR44_RS14330	COG1486	melibiose metabolic process
IAR44_RS14340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAR44_RS14355	COG2202	Pas domain
IAR44_RS14355	COG1366	Belongs to the anti-sigma-factor antagonist family
IAR44_RS14360	COG2814	Major facilitator Superfamily
IAR44_RS14365	COG5522	Integral membrane protein (intg_mem_TP0381)
IAR44_RS14375	COG0577	efflux transmembrane transporter activity
IAR44_RS14380	COG1136	(ABC) transporter
IAR44_RS14385	COG2205	protein histidine kinase activity
IAR44_RS14390	COG0745	RESPONSE REGULATOR receiver
IAR44_RS14395	COG0577	efflux transmembrane transporter activity
IAR44_RS14400	COG1136	(ABC) transporter
IAR44_RS14420	COG1131	(ABC) transporter
IAR44_RS14425	COG1725	Transcriptional regulator
IAR44_RS14435	COG0640	Transcriptional regulator
IAR44_RS14440	COG0477	Major facilitator Superfamily
IAR44_RS14445	COG1242	4 iron, 4 sulfur cluster binding
IAR44_RS14450	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IAR44_RS14460	COG0584	glycerophosphoryl diester phosphodiesterase
IAR44_RS14470	COG2267	carboxylic ester hydrolase activity
IAR44_RS14475	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IAR44_RS14480	COG1113	amino acid transport
IAR44_RS14485	COG0367	asparagine synthase
IAR44_RS14505	COG1506	peptidase
IAR44_RS14510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAR44_RS14515	COG1116	anion transmembrane transporter activity
IAR44_RS14520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAR44_RS14525	COG0494	nUDIX hydrolase
IAR44_RS14530	COG4824	toxin secretion phage lysis holin
IAR44_RS14535	COG0783	Belongs to the Dps family
IAR44_RS14560	COG0288	reversible hydration of carbon dioxide
IAR44_RS14570	COG1271	oxidase subunit
IAR44_RS14575	COG1294	oxidase, subunit
IAR44_RS14585	COG4948	Mandelate Racemase Muconate Lactonizing
IAR44_RS14595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAR44_RS14600	COG0596	Alpha beta hydrolase
IAR44_RS14610	COG1169	isochorismate synthase
IAR44_RS14615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAR44_RS14620	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IAR44_RS14745	COG3859	Proton-coupled thiamine transporter YuaJ
IAR44_RS14750	COG2268	Band 7 protein
IAR44_RS14755	COG1585	Membrane protein implicated in regulation of membrane protease activity
IAR44_RS14760	COG2318	DinB family
IAR44_RS14770	COG1454	alcohol dehydrogenase
IAR44_RS14775	COG1012	belongs to the aldehyde dehydrogenase family
IAR44_RS14780	COG1510	regulation of RNA biosynthetic process
IAR44_RS14790	COG0569	domain protein
IAR44_RS14795	COG1705	Flagellar rod assembly protein muramidase FlgJ
IAR44_RS14800	COG1017	nitric oxide dioxygenase activity
IAR44_RS14800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAR44_RS14845	COG0628	permease
IAR44_RS14850	COG0673	inositol 2-dehydrogenase activity
IAR44_RS14855	COG0693	protein deglycase activity
IAR44_RS14860	COG0840	transmembrane signaling receptor activity
IAR44_RS14865	COG0840	transmembrane signaling receptor activity
IAR44_RS14870	COG0840	transmembrane signaling receptor activity
IAR44_RS14875	COG0840	transmembrane signaling receptor activity
IAR44_RS14890	COG2070	2-Nitropropane dioxygenase
IAR44_RS14895	COG0432	Pfam Uncharacterised protein family UPF0047
IAR44_RS14900	COG0366	Alpha amylase catalytic
IAR44_RS14905	COG1253	flavin adenine dinucleotide binding
IAR44_RS14910	COG2738	Putative neutral zinc metallopeptidase
IAR44_RS14925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IAR44_RS14950	COG1335	isochorismatase
IAR44_RS14955	COG1979	alcohol dehydrogenase
IAR44_RS14960	COG1979	alcohol dehydrogenase
IAR44_RS14965	COG2155	Conserved Protein
IAR44_RS14970	COG1098	S1 RNA binding domain
IAR44_RS14975	COG0436	Aminotransferase
IAR44_RS14980	COG1522	sequence-specific DNA binding
IAR44_RS14985	COG2267	carboxylic ester hydrolase activity
IAR44_RS14995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IAR44_RS15000	COG2205	protein histidine kinase activity
IAR44_RS15010	COG5018	Exonuclease
IAR44_RS15015	COG2814	Major facilitator Superfamily
IAR44_RS15020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAR44_RS15025	COG3011	Protein conserved in bacteria
IAR44_RS15035	COG3290	protein histidine kinase activity
IAR44_RS15040	COG4565	transcriptional regulatory protein
IAR44_RS15045	COG1744	ABC transporter substrate-binding protein PnrA-like
IAR44_RS15050	COG3845	ABC transporter
IAR44_RS15055	COG4603	Belongs to the binding-protein-dependent transport system permease family
IAR44_RS15060	COG1079	Belongs to the binding-protein-dependent transport system permease family
IAR44_RS15070	COG2111	Na H antiporter
IAR44_RS15070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAR44_RS15075	COG2111	Na H antiporter
IAR44_RS15080	COG1006	Multisubunit Na H antiporter MnhC subunit
IAR44_RS15085	COG0651	ATP synthesis coupled electron transport
IAR44_RS15090	COG1863	multisubunit Na H antiporter MnhE subunit
IAR44_RS15095	COG2212	antiporter activity
IAR44_RS15100	COG1320	monovalent cation:proton antiporter activity
IAR44_RS15105	COG2050	protein possibly involved in aromatic compounds catabolism
IAR44_RS15110	COG2197	response regulator
IAR44_RS15115	COG4585	Histidine kinase
IAR44_RS15125	COG0142	geranyltranstransferase activity
IAR44_RS15140	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IAR44_RS15145	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAR44_RS15150	COG1335	isochorismatase
IAR44_RS15155	COG5506	Protein of unknown function (DUF1694)
IAR44_RS15170	COG0628	permease
IAR44_RS15180	COG1418	mRNA catabolic process
IAR44_RS15185	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS15195	COG1511	domain protein
IAR44_RS15200	COG1674	ftsk spoiiie
IAR44_RS15200	COG0433	COG0433 Predicted ATPase
IAR44_RS15205	COG4499	WXG100 protein secretion system (Wss), protein YukC
IAR44_RS15210	COG5417	Belongs to the EsaB family
IAR44_RS15215	COG4842	Belongs to the WXG100 family
IAR44_RS15220	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IAR44_RS15220	COG2508	Transcriptional regulator
IAR44_RS15225	COG0686	Belongs to the AlaDH PNT family
IAR44_RS15230	COG5634	Uncharacterized conserved protein (DUF2278)
IAR44_RS15235	COG3251	PFAM MbtH domain protein
IAR44_RS15240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAR44_RS15245	COG1535	isochorismatase
IAR44_RS15245	COG3433	isochorismatase activity
IAR44_RS15250	COG1021	2,3-dihydroxybenzoate-AMP ligase
IAR44_RS15255	COG1169	isochorismate synthase
IAR44_RS15260	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS15265	COG2819	hydrolase of the alpha beta superfamily
IAR44_RS15270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IAR44_RS15275	COG1268	BioY protein
IAR44_RS15280	COG2056	Na+-H+ antiporter family
IAR44_RS15290	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
IAR44_RS15295	COG3584	3D domain protein
IAR44_RS15310	COG1252	NADH dehydrogenase
IAR44_RS15340	COG1131	(ABC) transporter
IAR44_RS15360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAR44_RS15365	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
IAR44_RS15370	COG0316	Belongs to the HesB IscA family
IAR44_RS15380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAR44_RS15390	COG1252	NADH dehydrogenase
IAR44_RS15395	COG4837	Protein of unknown function (DUF1462)
IAR44_RS15400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IAR44_RS15405	COG4946	Tricorn protease homolog
IAR44_RS15405	COG1506	peptidase
IAR44_RS15405	COG0823	Involved in the tonB-independent uptake of proteins
IAR44_RS15415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IAR44_RS15420	COG0460	homoserine dehydrogenase
IAR44_RS15425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IAR44_RS15430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IAR44_RS15435	COG0647	UMP catabolic process
IAR44_RS15440	COG2445	Protein of unknown function DUF86
IAR44_RS15445	COG4470	Protein conserved in bacteria
IAR44_RS15455	COG0739	heme binding
IAR44_RS15465	COG0737	Belongs to the 5'-nucleotidase family
IAR44_RS15470	COG0730	response to heat
IAR44_RS15475	COG1801	Protein of unknown function DUF72
IAR44_RS15490	COG2508	Transcriptional regulator
IAR44_RS15495	COG0457	Tetratricopeptide repeat
IAR44_RS15505	COG2814	Major facilitator Superfamily
IAR44_RS15510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IAR44_RS15515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAR44_RS15520	COG2356	endonuclease I
IAR44_RS15525	COG3842	ATPase activity
IAR44_RS15530	COG2188	Transcriptional regulator
IAR44_RS15535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAR44_RS15540	COG0395	ABC-type sugar transport system, permease component
IAR44_RS15545	COG1175	transmembrane transport
IAR44_RS15550	COG1653	transport
IAR44_RS15555	COG2222	sugar isomerase
IAR44_RS15560	COG0789	Transcriptional regulator
IAR44_RS15575	COG0322	excinuclease ABC activity
IAR44_RS15580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAR44_RS15585	COG2226	methyltransferase
IAR44_RS15595	COG3409	Peptidoglycan-binding domain 1 protein
IAR44_RS15600	COG0719	Fe-S assembly protein
IAR44_RS15605	COG0822	iron-sulfur transferase activity
IAR44_RS15610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAR44_RS15615	COG0719	Fe-S assembly protein
IAR44_RS15620	COG0396	ATPase activity
IAR44_RS15630	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAR44_RS15635	COG1464	Belongs to the NlpA lipoprotein family
IAR44_RS15640	COG2011	ABC-type metal ion transport system permease component
IAR44_RS15645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAR44_RS15655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAR44_RS15660	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IAR44_RS15675	COG1393	Belongs to the ArsC family
IAR44_RS15680	COG1960	acyl-CoA dehydrogenase activity
IAR44_RS15685	COG0183	Belongs to the thiolase family
IAR44_RS15690	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAR44_RS15690	COG1024	Enoyl-CoA hydratase
IAR44_RS15705	COG0477	Major facilitator Superfamily
IAR44_RS15715	COG5577	PFAM Coat F domain
IAR44_RS15720	COG1846	Transcriptional regulator
IAR44_RS15725	COG0477	Major facilitator Superfamily
IAR44_RS15730	COG1942	4-Oxalocrotonate Tautomerase
IAR44_RS15735	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS15740	COG0583	DNA-binding transcription factor activity
IAR44_RS15750	COG0583	DNA-binding transcription factor activity
IAR44_RS15770	COG1120	ATPase activity
IAR44_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS15790	COG0783	Belongs to the Dps family
IAR44_RS15795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAR44_RS15800	COG0745	RESPONSE REGULATOR receiver
IAR44_RS15805	COG2770	Histidine kinase
IAR44_RS15805	COG2205	protein histidine kinase activity
IAR44_RS15815	COG1309	transcriptional regulator
IAR44_RS15820	COG0114	fumarate hydratase activity
IAR44_RS15830	COG0697	spore germination
IAR44_RS15835	COG0814	amino acid
IAR44_RS15845	COG2197	response regulator
IAR44_RS15850	COG4585	Histidine kinase
IAR44_RS15855	COG4758	membrane
IAR44_RS15860	COG3595	metallopeptidase activity
IAR44_RS15865	COG1842	Phage shock protein A
IAR44_RS15870	COG4758	membrane
IAR44_RS15875	COG2814	Major facilitator Superfamily
IAR44_RS15880	COG2096	Adenosyltransferase
IAR44_RS15885	COG1120	ATPase activity
IAR44_RS15890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAR44_RS15895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAR44_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS15905	COG3386	PFAM SMP-30 Gluconolaconase
IAR44_RS15910	COG2205	protein histidine kinase activity
IAR44_RS15915	COG0745	RESPONSE REGULATOR receiver
IAR44_RS15925	COG1191	sigma factor activity
IAR44_RS15935	COG2140	Oxalate decarboxylase
IAR44_RS15945	COG1120	ATPase activity
IAR44_RS15950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAR44_RS15955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAR44_RS15960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAR44_RS15965	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IAR44_RS15970	COG0531	amino acid
IAR44_RS15980	COG1988	membrane-bound metal-dependent
IAR44_RS15985	COG1368	sulfuric ester hydrolase activity
IAR44_RS15990	COG1910	domain protein
IAR44_RS15995	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAR44_RS16000	COG4149	molybdate abc transporter
IAR44_RS16005	COG2197	response regulator
IAR44_RS16010	COG3850	Histidine kinase
IAR44_RS16015	COG1131	(ABC) transporter
IAR44_RS16025	COG0842	Transport permease protein
IAR44_RS16030	COG0656	L-ascorbic acid biosynthetic process
IAR44_RS16050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IAR44_RS16055	COG3973	AAA domain
IAR44_RS16060	COG2860	membrane
IAR44_RS16070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IAR44_RS16075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAR44_RS16080	COG2217	Heavy metal translocating P-type atpase
IAR44_RS16085	COG2217	Heavy metal translocating P-type atpase
IAR44_RS16090	COG2608	mercury ion transmembrane transporter activity
IAR44_RS16095	COG1937	Protein conserved in bacteria
IAR44_RS16100	COG0673	inositol 2-dehydrogenase activity
IAR44_RS16115	COG2814	Major facilitator Superfamily
IAR44_RS16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAR44_RS16135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IAR44_RS16140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAR44_RS16145	COG1126	abc transporter atp-binding protein
IAR44_RS16150	COG0765	amino acid transport
IAR44_RS16155	COG0765	amino acid transport
IAR44_RS16160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAR44_RS16165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAR44_RS16170	COG0454	-acetyltransferase
IAR44_RS16175	COG0583	DNA-binding transcription factor activity
IAR44_RS16180	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS16185	COG2732	(Barnase) inhibitor
IAR44_RS16200	COG0557	exoribonuclease II activity
IAR44_RS16205	COG1647	Serine aminopeptidase, S33
IAR44_RS16210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAR44_RS16215	COG1476	TRANSCRIPTIONal
IAR44_RS16220	COG1396	sequence-specific DNA binding
IAR44_RS16225	COG1396	sequence-specific DNA binding
IAR44_RS16230	COG1733	regulation of RNA biosynthetic process
IAR44_RS16255	COG1131	(ABC) transporter
IAR44_RS16260	COG1174	glycine betaine transport
IAR44_RS16265	COG1732	Glycine betaine
IAR44_RS16270	COG1174	glycine betaine transport
IAR44_RS16275	COG0517	IMP dehydrogenase activity
IAR44_RS16275	COG1125	glycine betaine transport
IAR44_RS16280	COG1510	regulation of RNA biosynthetic process
IAR44_RS16285	COG1174	glycine betaine transport
IAR44_RS16290	COG1732	Glycine betaine
IAR44_RS16295	COG1174	glycine betaine transport
IAR44_RS16300	COG1125	glycine betaine transport
IAR44_RS16300	COG0517	IMP dehydrogenase activity
IAR44_RS16305	COG1510	regulation of RNA biosynthetic process
IAR44_RS16310	COG2095	MarC family integral membrane protein
IAR44_RS16315	COG3064	Membrane
IAR44_RS16320	COG4640	response to antibiotic
IAR44_RS16325	COG0456	acetyltransferase
IAR44_RS16340	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAR44_RS16360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAR44_RS16365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IAR44_RS16375	COG2234	aminopeptidase activity
IAR44_RS16395	COG0126	phosphoglycerate kinase activity
IAR44_RS16400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAR44_RS16405	COG2390	Transcriptional regulator
IAR44_RS16410	COG2814	Major facilitator Superfamily
IAR44_RS16415	COG1609	Transcriptional regulator
IAR44_RS16425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAR44_RS16430	COG0583	DNA-binding transcription factor activity
IAR44_RS16435	COG0697	spore germination
IAR44_RS16440	COG1113	amino acid transport
IAR44_RS16450	COG1609	Transcriptional regulator
IAR44_RS16460	COG0561	phosphatase activity
IAR44_RS16465	COG1737	Transcriptional regulator
IAR44_RS16470	COG1070	Carbohydrate kinase
IAR44_RS16495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAR44_RS16500	COG2186	Transcriptional regulator
IAR44_RS16505	COG1620	l-lactate permease
IAR44_RS16510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IAR44_RS16520	COG5039	Polysaccharide pyruvyl transferase
IAR44_RS16525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IAR44_RS16530	COG0110	maltose O-acetyltransferase activity
IAR44_RS16535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IAR44_RS16540	COG2244	polysaccharide biosynthetic process
IAR44_RS16545	COG1216	Glycosyl transferase, family 2
IAR44_RS16550	COG5039	Polysaccharide pyruvyl transferase
IAR44_RS16555	COG1216	Glycosyl transferase, family 2
IAR44_RS16565	COG0438	transferase activity, transferring glycosyl groups
IAR44_RS16570	COG1215	transferase activity, transferring glycosyl groups
IAR44_RS16575	COG0438	transferase activity, transferring glycosyl groups
IAR44_RS16580	COG1086	Polysaccharide biosynthesis protein
IAR44_RS16585	COG0489	protein tyrosine kinase activity
IAR44_RS16590	COG3944	biosynthesis protein
IAR44_RS16595	COG1396	sequence-specific DNA binding
IAR44_RS16600	COG2272	Belongs to the type-B carboxylesterase lipase family
IAR44_RS16605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAR44_RS16610	COG2364	Membrane
IAR44_RS16615	COG0456	acetyltransferase
IAR44_RS16620	COG3479	Phenolic acid decarboxylase
IAR44_RS16685	COG2223	nitrite transmembrane transporter activity
IAR44_RS16690	COG1609	Transcriptional regulator
IAR44_RS16700	COG0583	DNA-binding transcription factor activity
IAR44_RS16705	COG2828	Protein conserved in bacteria
IAR44_RS16710	COG0477	Major facilitator Superfamily
IAR44_RS16710	COG2814	Major facilitator Superfamily
IAR44_RS16715	COG1611	Belongs to the LOG family
IAR44_RS16720	COG1694	Mazg nucleotide pyrophosphohydrolase
IAR44_RS16725	COG0659	secondary active sulfate transmembrane transporter activity
IAR44_RS16730	COG0288	reversible hydration of carbon dioxide
IAR44_RS16735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAR44_RS16740	COG4290	ribonuclease
IAR44_RS16750	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IAR44_RS16755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAR44_RS16765	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IAR44_RS16775	COG1051	belongs to the nudix hydrolase family
IAR44_RS16780	COG0492	ferredoxin-NADP+ reductase activity
IAR44_RS16785	COG0791	NLP P60 protein
IAR44_RS16785	COG3883	PFAM NLP P60 protein
IAR44_RS16790	COG0457	Tetratricopeptide repeat
IAR44_RS16795	COG5002	protein histidine kinase activity
IAR44_RS16800	COG0745	RESPONSE REGULATOR receiver
IAR44_RS16810	COG1132	(ABC) transporter
IAR44_RS16815	COG0140	phosphoribosyl-ATP diphosphatase activity
IAR44_RS16815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IAR44_RS16840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAR44_RS16855	COG4990	cell redox homeostasis
IAR44_RS16860	COG0110	maltose O-acetyltransferase activity
IAR44_RS16880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAR44_RS16890	COG2188	Transcriptional regulator
IAR44_RS16895	COG1309	transcriptional regulator
IAR44_RS16900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAR44_RS16905	COG1950	PFAM Membrane protein of
IAR44_RS16910	COG1983	PspC domain protein
IAR44_RS16915	COG3595	metallopeptidase activity
IAR44_RS16930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IAR44_RS16940	COG4897	Protein conserved in bacteria
IAR44_RS16945	COG0574	Belongs to the PEP-utilizing enzyme family
IAR44_RS16945	COG3848	Pyruvate phosphate dikinase
IAR44_RS16950	COG1309	transcriptional regulator
IAR44_RS16955	COG2814	Major facilitator Superfamily
IAR44_RS16965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAR44_RS16975	COG0793	Belongs to the peptidase S41A family
IAR44_RS16975	COG3409	Peptidoglycan-binding domain 1 protein
IAR44_RS16980	COG3420	alginic acid biosynthetic process
IAR44_RS16985	COG2177	Part of the ABC transporter FtsEX involved in
IAR44_RS16990	COG2884	Cell division ATP-binding protein ftsE
IAR44_RS16995	COG2010	Cytochrome c
IAR44_RS17000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAR44_RS17015	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAR44_RS17030	COG1516	flagellar protein fliS
IAR44_RS17035	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IAR44_RS17040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IAR44_RS17060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IAR44_RS17065	COG4786	Flagellar basal body rod
IAR44_RS17065	COG1256	bacterial-type flagellum assembly
IAR44_RS17070	COG3418	PFAM FlgN family protein
IAR44_RS17075	COG2747	anti-sigma28 factor FlgM
IAR44_RS17085	COG1040	competence protein
IAR44_RS17095	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IAR44_RS17100	COG1307	EDD domain protein, DegV family
IAR44_RS17105	COG2197	response regulator
IAR44_RS17110	COG4585	Histidine kinase
IAR44_RS17115	COG1739	Uncharacterized protein family UPF0029
IAR44_RS17120	COG1316	TRANSCRIPTIONal
IAR44_RS17125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAR44_RS17130	COG0438	transferase activity, transferring glycosyl groups
IAR44_RS17135	COG1215	transferase activity, transferring glycosyl groups
IAR44_RS17140	COG3206	protein involved in exopolysaccharide biosynthesis
IAR44_RS17145	COG3307	-O-antigen
IAR44_RS17150	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAR44_RS17155	COG0438	transferase activity, transferring glycosyl groups
IAR44_RS17155	COG0297	glycogen (starch) synthase activity
IAR44_RS17160	COG2244	polysaccharide biosynthetic process
IAR44_RS17170	COG2247	cell wall binding repeat
IAR44_RS17170	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAR44_RS17175	COG2247	cell wall binding repeat
IAR44_RS17175	COG2385	sporulation resulting in formation of a cellular spore
IAR44_RS17185	COG1316	TRANSCRIPTIONal
IAR44_RS17190	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IAR44_RS17195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAR44_RS17200	COG1134	teichoic acid transport
IAR44_RS17205	COG1682	transport, permease protein
IAR44_RS17210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAR44_RS17215	COG0438	transferase activity, transferring glycosyl groups
IAR44_RS17220	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IAR44_RS17225	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IAR44_RS17230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAR44_RS17235	COG4193	domain, Protein
IAR44_RS17240	COG1482	cell wall glycoprotein biosynthetic process
IAR44_RS17245	COG0697	spore germination
IAR44_RS17250	COG0814	amino acid
IAR44_RS17260	COG1215	transferase activity, transferring glycosyl groups
IAR44_RS17265	COG2814	Major facilitator Superfamily
IAR44_RS17270	COG1316	TRANSCRIPTIONal
IAR44_RS17275	COG0561	phosphatase activity
IAR44_RS17280	COG2433	Pfam Transposase IS66
IAR44_RS17285	COG0791	NLP P60 protein
IAR44_RS17295	COG2843	Capsule synthesis protein
IAR44_RS17305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAR44_RS17310	COG0697	spore germination
IAR44_RS17315	COG0814	amino acid
IAR44_RS17325	COG1609	Transcriptional regulator
IAR44_RS17330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAR44_RS17340	COG1129	ABC transporter
IAR44_RS17345	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAR44_RS17350	COG1879	ABC-type sugar transport system periplasmic component
IAR44_RS17355	COG3103	Sh3 type 3 domain protein
IAR44_RS17360	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAR44_RS17365	COG3527	Alpha-acetolactate decarboxylase
IAR44_RS17370	COG0028	Belongs to the TPP enzyme family
IAR44_RS17375	COG0583	DNA-binding transcription factor activity
IAR44_RS17380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAR44_RS17395	COG5337	Spore coat protein CotH
IAR44_RS17405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAR44_RS17415	COG0405	Gamma-glutamyltransferase
IAR44_RS17420	COG1522	sequence-specific DNA binding
IAR44_RS17425	COG2059	Chromate
IAR44_RS17430	COG2059	Chromate
IAR44_RS17455	COG5444	nuclease activity
IAR44_RS17470	COG3878	Protein conserved in bacteria
IAR44_RS17475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAR44_RS17480	COG4464	protein tyrosine phosphatase activity
IAR44_RS17485	COG0489	protein tyrosine kinase activity
IAR44_RS17490	COG3944	biosynthesis protein
IAR44_RS17500	COG4715	Zinc finger, swim domain protein
IAR44_RS17505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAR44_RS17510	COG0561	phosphatase activity
IAR44_RS17515	COG1349	DNA-binding transcription factor activity
IAR44_RS17520	COG0629	single-stranded DNA binding
IAR44_RS17545	COG0457	Tetratricopeptide repeat
IAR44_RS17550	COG4786	Flagellar basal body rod
IAR44_RS17555	COG4786	Flagellar basal body rod
IAR44_RS17560	COG1077	Cell shape determining protein MreB Mrl
IAR44_RS17565	COG1609	Transcriptional regulator
IAR44_RS17570	COG1846	Transcriptional regulator
IAR44_RS17575	COG2814	Major facilitator Superfamily
IAR44_RS17580	COG1953	Uracil, thiamine, allantoin
IAR44_RS17585	COG0477	Major facilitator Superfamily
IAR44_RS17590	COG1335	isochorismatase
IAR44_RS17595	COG0004	ammonium transporteR
IAR44_RS17600	COG0347	Belongs to the P(II) protein family
IAR44_RS17605	COG0772	Belongs to the SEDS family
IAR44_RS17610	COG0671	phosphoesterase, PA-phosphatase related
IAR44_RS17620	COG0739	heme binding
IAR44_RS17625	COG1247	-acetyltransferase
IAR44_RS17640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAR44_RS17650	COG0726	polysaccharide deacetylase
IAR44_RS17655	COG1959	2 iron, 2 sulfur cluster binding
IAR44_RS17670	COG0831	urea catabolic process
IAR44_RS17680	COG1994	Peptidase M50
IAR44_RS17685	COG0457	Tetratricopeptide repeat
IAR44_RS17695	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IAR44_RS17705	COG2304	oxidoreductase activity
IAR44_RS17710	COG2304	oxidoreductase activity
IAR44_RS17715	COG2385	sporulation resulting in formation of a cellular spore
IAR44_RS17720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAR44_RS17730	COG4836	Membrane
IAR44_RS17800	COG0698	ribose 5-phosphate isomerase
IAR44_RS17805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAR44_RS17815	COG0009	L-threonylcarbamoyladenylate synthase
IAR44_RS17820	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IAR44_RS17840	COG2890	protein-(glutamine-N5) methyltransferase activity
IAR44_RS17845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAR44_RS17850	COG0346	lactoylglutathione lyase activity
IAR44_RS17855	COG0789	Transcriptional regulator
IAR44_RS17860	COG0679	Auxin Efflux Carrier
IAR44_RS17865	COG0281	malic enzyme
IAR44_RS17880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IAR44_RS17885	COG1494	fructose-1,6-bisphosphatase
IAR44_RS17890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAR44_RS17900	COG0191	fructose-bisphosphate aldolase activity
IAR44_RS17905	COG2204	response regulator
IAR44_RS17910	COG4821	SIS domain
IAR44_RS17925	COG0247	lactate metabolic process
IAR44_RS17925	COG2181	nitrate reductase activity
IAR44_RS17930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAR44_RS17945	COG1132	(ABC) transporter
IAR44_RS17950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAR44_RS17960	COG2181	nitrate reductase activity
IAR44_RS17965	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IAR44_RS17970	COG1140	nitrate reductase beta subunit
IAR44_RS17975	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAR44_RS17980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAR44_RS17990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAR44_RS17995	COG2223	nitrite transmembrane transporter activity
IAR44_RS18005	COG4506	Protein conserved in bacteria
IAR44_RS18015	COG3391	amine dehydrogenase activity
IAR44_RS18020	COG3391	amine dehydrogenase activity
IAR44_RS18025	COG0457	Tetratricopeptide repeat
IAR44_RS18065	COG0010	Belongs to the arginase family
IAR44_RS18070	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IAR44_RS18075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAR44_RS18090	COG1994	Peptidase M50
IAR44_RS18095	COG1942	4-Oxalocrotonate Tautomerase
IAR44_RS18100	COG1846	Transcriptional regulator
IAR44_RS18105	COG0531	amino acid
IAR44_RS18110	COG3465	dGTPase activity
IAR44_RS18115	COG1078	dGTPase activity
IAR44_RS18130	COG1695	Transcriptional regulator
IAR44_RS18140	COG1131	(ABC) transporter
IAR44_RS18145	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IAR44_RS18175	COG0583	DNA-binding transcription factor activity
IAR44_RS18180	COG2855	membrane
IAR44_RS18185	COG0280	phosphate acetyltransferase
IAR44_RS18195	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS18200	COG0436	Aminotransferase
IAR44_RS18230	COG2814	Major facilitator Superfamily
IAR44_RS18235	COG2814	Major facilitator Superfamily
IAR44_RS18240	COG0833	amino acid
IAR44_RS18245	COG4187	Peptidase family M20/M25/M40
IAR44_RS18250	COG1012	belongs to the aldehyde dehydrogenase family
IAR44_RS18255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAR44_RS18265	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IAR44_RS18270	COG1091	dTDP-4-dehydrorhamnose reductase activity
IAR44_RS18275	COG1088	dTDP-glucose 4,6-dehydratase activity
IAR44_RS18280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IAR44_RS18285	COG3980	spore coat polysaccharide biosynthesis protein
IAR44_RS18290	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
IAR44_RS18295	COG2089	acid synthase
IAR44_RS18300	COG0456	acetyltransferase
IAR44_RS18305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IAR44_RS18310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAR44_RS18315	COG0463	Glycosyl transferase, family 2
IAR44_RS18325	COG2363	Small membrane protein
IAR44_RS18330	COG2233	PERMEase
IAR44_RS18345	COG1216	Glycosyl transferase, family 2
IAR44_RS18360	COG1695	Transcriptional regulator
IAR44_RS18365	COG0351	phosphomethylpyrimidine kinase
IAR44_RS18375	COG1621	beta-fructofuranosidase activity
IAR44_RS18380	COG1263	PTS System
IAR44_RS18380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAR44_RS18385	COG3711	transcriptional antiterminator
IAR44_RS18395	COG1404	Belongs to the peptidase S8 family
IAR44_RS18400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAR44_RS18405	COG0778	Nitroreductase
IAR44_RS18410	COG0772	Belongs to the SEDS family
IAR44_RS18415	COG0454	-acetyltransferase
IAR44_RS18435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAR44_RS18440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAR44_RS18445	COG2261	transglycosylase associated protein
IAR44_RS18450	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IAR44_RS18455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAR44_RS18460	COG2246	polysaccharide biosynthetic process
IAR44_RS18465	COG1309	transcriptional regulator
IAR44_RS18485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAR44_RS18490	COG2837	iron assimilation
IAR44_RS18495	COG2822	iron ion transport
IAR44_RS18510	COG0583	DNA-binding transcription factor activity
IAR44_RS18520	COG1346	cytolysis
IAR44_RS18525	COG4895	conserved protein (DUF2196)
IAR44_RS18530	COG0789	Transcriptional regulator
IAR44_RS18535	COG5504	Zn-dependent protease
IAR44_RS18540	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IAR44_RS18545	COG0346	lactoylglutathione lyase activity
IAR44_RS18550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAR44_RS18555	COG1404	Belongs to the peptidase S8 family
IAR44_RS18560	COG1442	glycosyl transferase family 8
IAR44_RS18565	COG2357	RelA SpoT domain protein
IAR44_RS18570	COG1575	Belongs to the MenA family. Type 1 subfamily
IAR44_RS18585	COG1696	Membrane protein involved in D-alanine export
IAR44_RS18595	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IAR44_RS18600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAR44_RS18605	COG1486	melibiose metabolic process
IAR44_RS18610	COG1447	Phosphotransferase system cellobiose-specific component IIA
IAR44_RS18615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAR44_RS18620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAR44_RS18625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAR44_RS18625	COG3711	transcriptional antiterminator
IAR44_RS18635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAR44_RS18640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAR44_RS18645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAR44_RS18650	COG0640	Transcriptional regulator
IAR44_RS18655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAR44_RS18660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAR44_RS18665	COG1447	Phosphotransferase system cellobiose-specific component IIA
IAR44_RS18670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAR44_RS18675	COG2723	6-phospho-beta-galactosidase activity
IAR44_RS18680	COG1940	carbohydrate kinase activity
IAR44_RS18685	COG1482	cell wall glycoprotein biosynthetic process
IAR44_RS18695	COG0753	catalase activity
IAR44_RS18700	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IAR44_RS18705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IAR44_RS18710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IAR44_RS18715	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IAR44_RS18720	COG4988	ABC transporter
IAR44_RS18725	COG1294	oxidase, subunit
IAR44_RS18730	COG1271	oxidase subunit
IAR44_RS18735	COG3493	citrate carrier protein
IAR44_RS18740	COG0726	polysaccharide deacetylase
IAR44_RS18745	COG3842	ATPase activity
IAR44_RS18750	COG2508	Transcriptional regulator
IAR44_RS18755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAR44_RS18765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAR44_RS18780	COG4894	glucomannan catabolic process
IAR44_RS18785	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAR44_RS18790	COG0500	methyltransferase
IAR44_RS18795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAR44_RS18815	COG0693	protein deglycase activity
IAR44_RS18815	COG0753	catalase activity
IAR44_RS18820	COG2851	Citrate transporter
IAR44_RS18825	COG2273	Hydrolase Family 16
IAR44_RS18830	COG3711	transcriptional antiterminator
IAR44_RS18835	COG2270	Major facilitator Superfamily
IAR44_RS18840	COG0513	Belongs to the DEAD box helicase family
IAR44_RS18920	COG0697	spore germination
IAR44_RS18925	COG0589	response to stress
IAR44_RS18940	COG0494	nUDIX hydrolase
IAR44_RS18945	COG3507	Belongs to the glycosyl hydrolase 43 family
IAR44_RS18970	COG0010	Belongs to the arginase family
IAR44_RS18975	COG0833	amino acid
IAR44_RS18980	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IAR44_RS18985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAR44_RS18995	COG2390	Transcriptional regulator
IAR44_RS19000	COG0561	phosphatase activity
IAR44_RS19030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAR44_RS19035	COG5294	Protein conserved in bacteria
IAR44_RS19040	COG0577	efflux transmembrane transporter activity
IAR44_RS19045	COG1136	(ABC) transporter
IAR44_RS19050	COG2205	protein histidine kinase activity
IAR44_RS19055	COG0745	RESPONSE REGULATOR receiver
IAR44_RS19060	COG2205	protein histidine kinase activity
IAR44_RS19065	COG0745	RESPONSE REGULATOR receiver
IAR44_RS19095	COG1082	Xylose isomerase domain protein TIM barrel
IAR44_RS19105	COG2814	Major facilitator Superfamily
IAR44_RS19135	COG1349	DNA-binding transcription factor activity
IAR44_RS19140	COG0667	Aldo Keto reductase
IAR44_RS19145	COG2814	Major facilitator Superfamily
IAR44_RS19155	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS19160	COG2197	response regulator
IAR44_RS19165	COG4585	Histidine kinase
IAR44_RS19170	COG3239	Fatty acid desaturase
IAR44_RS19175	COG1309	transcriptional regulator
IAR44_RS19180	COG1012	belongs to the aldehyde dehydrogenase family
IAR44_RS19185	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAR44_RS19195	COG0640	Transcriptional regulator
IAR44_RS19200	COG2814	Major facilitator Superfamily
IAR44_RS19205	COG1714	RDD family
IAR44_RS19215	COG0501	Belongs to the peptidase M48B family
IAR44_RS19220	COG1715	Restriction endonuclease
IAR44_RS19225	COG0450	alkyl hydroperoxide reductase
IAR44_RS19230	COG3634	alkyl hydroperoxide reductase activity
IAR44_RS19235	COG3177	Filamentation induced by cAMP protein fic
IAR44_RS19240	COG1113	amino acid transport
IAR44_RS19250	COG2080	2 iron, 2 sulfur cluster binding
IAR44_RS19265	COG2068	MobA-Related Protein
IAR44_RS19270	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IAR44_RS19325	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IAR44_RS19330	COG0667	Aldo Keto reductase
IAR44_RS19335	COG0456	acetyltransferase
IAR44_RS19340	COG0457	Tetratricopeptide repeat
IAR44_RS19345	COG0010	Belongs to the arginase family
IAR44_RS19350	COG0833	amino acid
IAR44_RS19355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAR44_RS19360	COG5658	integral membrane protein
IAR44_RS19365	COG0640	Transcriptional regulator
IAR44_RS19370	COG3829	transcription factor binding
IAR44_RS19380	COG0488	(ABC) transporter
IAR44_RS19395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAR44_RS19400	COG3850	Histidine kinase
IAR44_RS19400	COG5002	protein histidine kinase activity
IAR44_RS19405	COG0745	RESPONSE REGULATOR receiver
IAR44_RS19410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAR44_RS19415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IAR44_RS19420	COG4853	Protein conserved in bacteria
IAR44_RS19425	COG4863	YycH protein
IAR44_RS19430	COG5002	protein histidine kinase activity
IAR44_RS19435	COG0745	RESPONSE REGULATOR receiver
IAR44_RS19465	COG0346	lactoylglutathione lyase activity
IAR44_RS19470	COG0305	Participates in initiation and elongation during chromosome replication
IAR44_RS19485	COG3093	addiction module antidote protein HigA
IAR44_RS19490	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAR44_RS19495	COG0297	glycogen (starch) synthase activity
IAR44_RS19505	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IAR44_RS19510	COG0438	transferase activity, transferring glycosyl groups
IAR44_RS19535	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
IAR44_RS19540	COG4241	membrane
IAR44_RS19550	COG5577	PFAM Coat F domain
IAR44_RS19555	COG1733	regulation of RNA biosynthetic process
IAR44_RS19565	COG0697	spore germination
IAR44_RS19570	COG1621	beta-fructofuranosidase activity
IAR44_RS19575	COG1621	beta-fructofuranosidase activity
IAR44_RS19580	COG1802	Transcriptional regulator
IAR44_RS19585	COG2318	DinB family
IAR44_RS19590	COG2211	Major facilitator Superfamily
IAR44_RS19595	COG0583	DNA-binding transcription factor activity
IAR44_RS19610	COG0778	Nitroreductase
IAR44_RS19615	COG1846	Transcriptional regulator
IAR44_RS19620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAR44_RS19625	COG1846	Transcriptional regulator
IAR44_RS19630	COG2153	protein acetylation
IAR44_RS19640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAR44_RS19645	COG0583	DNA-binding transcription factor activity
IAR44_RS19650	COG1028	Short-chain dehydrogenase reductase Sdr
IAR44_RS19655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAR44_RS19660	COG0697	spore germination
IAR44_RS19665	COG1331	Highly conserved protein containing a thioredoxin domain
IAR44_RS19675	COG0457	Tetratricopeptide repeat
IAR44_RS19695	COG0791	NLP P60 protein
IAR44_RS19695	COG0741	lytic transglycosylase activity
IAR44_RS19700	COG5644	endopeptidase inhibitor activity
IAR44_RS19710	COG0433	COG0433 Predicted ATPase
IAR44_RS19745	COG2946	Replication initiation factor
IAR44_RS19750	COG1674	ftsk spoiiie
IAR44_RS19775	COG1396	sequence-specific DNA binding
IAR44_RS19780	COG2856	Zn peptidase
IAR44_RS19785	COG1331	Highly conserved protein containing a thioredoxin domain
IAR44_RS19790	COG1331	Highly conserved protein containing a thioredoxin domain
IAR44_RS19795	COG1266	CAAX protease self-immunity
IAR44_RS19800	COG0477	Major facilitator Superfamily
IAR44_RS19800	COG2814	Major facilitator Superfamily
IAR44_RS19805	COG0346	lactoylglutathione lyase activity
IAR44_RS19810	COG1609	Transcriptional regulator
IAR44_RS19815	COG0708	Exodeoxyribonuclease III
IAR44_RS19820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAR44_RS19825	COG2169	Transcriptional regulator
IAR44_RS19835	COG0629	single-stranded DNA binding
IAR44_RS19845	COG0012	GTP binding
IAR44_RS19850	COG0243	molybdopterin cofactor binding
IAR44_RS19855	COG4481	Protein conserved in bacteria
IAR44_RS19860	COG3949	Membrane
IAR44_RS19875	COG1475	DNA binding
IAR44_RS19880	COG1192	Involved in chromosome partitioning
IAR44_RS19905	COG1847	R3H domain protein
IAR44_RS19910	COG0706	membrane insertase activity