CXR48_RS05470 2c462015278b469e06b35241ffd65edc 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 117 6.1E-16 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS05470 2c462015278b469e06b35241ffd65edc 140 Gene3D G3DSA:3.10.180.10 2 136 6.2E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS05470 2c462015278b469e06b35241ffd65edc 140 Hamap MF_01512 Metallothiol transferase FosB [fosB]. 2 139 42.019 T 29-03-2018 IPR022858 Metallothiol transferase FosB GO:0016765|GO:0046677 CXR48_RS05470 2c462015278b469e06b35241ffd65edc 140 SUPERFAMILY SSF54593 3 130 1.07E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 5.3E-141 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 SMART SM01230 105 354 4.8E-139 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 Gene3D G3DSA:3.10.20.70 2 104 6.5E-39 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 Gene3D G3DSA:3.30.590.10 105 444 8.3E-130 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 SUPERFAMILY SSF54368 5 104 4.71E-36 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 SUPERFAMILY SSF55931 105 442 4.12E-129 T 29-03-2018 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 99 1.0E-33 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CXR48_RS08715 081879ad1e11865044a66280aaff037b 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 3.8E-191 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CXR48_RS01455 5ef51fc5161de04cf55470ff42b23622 375 SUPERFAMILY SSF53383 7 372 3.63E-70 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS01455 5ef51fc5161de04cf55470ff42b23622 375 Pfam PF00266 Aminotransferase class-V 52 341 3.9E-46 T 29-03-2018 IPR000192 Aminotransferase class V domain CXR48_RS01455 5ef51fc5161de04cf55470ff42b23622 375 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 198 218 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CXR48_RS01455 5ef51fc5161de04cf55470ff42b23622 375 Gene3D G3DSA:3.40.640.10 29 267 7.2E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS01455 5ef51fc5161de04cf55470ff42b23622 375 Gene3D G3DSA:3.90.1150.10 268 372 2.3E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS01590 dc3bceac4814ab8dc8376523837e0696 293 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 172 6.7E-41 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CXR48_RS01590 dc3bceac4814ab8dc8376523837e0696 293 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 190 293 1.0E-22 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CXR48_RS01590 dc3bceac4814ab8dc8376523837e0696 293 Gene3D G3DSA:3.40.190.10 191 287 2.1E-15 T 29-03-2018 CXR48_RS01590 dc3bceac4814ab8dc8376523837e0696 293 SUPERFAMILY SSF53850 188 293 4.85E-28 T 29-03-2018 CXR48_RS01590 dc3bceac4814ab8dc8376523837e0696 293 Gene3D G3DSA:3.40.190.10 28 190 9.2E-40 T 29-03-2018 CXR48_RS01590 dc3bceac4814ab8dc8376523837e0696 293 SUPERFAMILY SSF53850 31 188 1.56E-50 T 29-03-2018 CXR48_RS11485 cb8f5dadac8a122ba39052d53dddfb63 240 SMART SM00382 26 213 4.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS11485 cb8f5dadac8a122ba39052d53dddfb63 240 Gene3D G3DSA:3.40.50.300 1 239 8.5E-81 T 29-03-2018 CXR48_RS11485 cb8f5dadac8a122ba39052d53dddfb63 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS11485 cb8f5dadac8a122ba39052d53dddfb63 240 PIRSF PIRSF039085 1 240 7.9E-116 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CXR48_RS11485 cb8f5dadac8a122ba39052d53dddfb63 240 Pfam PF00005 ABC transporter 17 165 4.0E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS11485 cb8f5dadac8a122ba39052d53dddfb63 240 SUPERFAMILY SSF52540 1 235 2.2E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS17925 e94d38e148acf23821e13080f21475e0 287 SUPERFAMILY SSF55729 124 279 2.92E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS17925 e94d38e148acf23821e13080f21475e0 287 Pfam PF00583 Acetyltransferase (GNAT) family 161 269 4.4E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS17925 e94d38e148acf23821e13080f21475e0 287 Gene3D G3DSA:3.40.630.30 127 286 3.1E-22 T 29-03-2018 CXR48_RS14690 662e9943c27e569408614d511e414b39 510 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS14690 662e9943c27e569408614d511e414b39 510 Pfam PF00005 ABC transporter 21 169 1.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS14690 662e9943c27e569408614d511e414b39 510 Pfam PF00005 ABC transporter 274 429 2.0E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS14690 662e9943c27e569408614d511e414b39 510 Gene3D G3DSA:3.40.50.300 250 496 7.8E-37 T 29-03-2018 CXR48_RS14690 662e9943c27e569408614d511e414b39 510 SMART SM00382 29 217 2.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS14690 662e9943c27e569408614d511e414b39 510 SUPERFAMILY SSF52540 256 488 1.41E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14690 662e9943c27e569408614d511e414b39 510 Gene3D G3DSA:3.40.50.300 1 243 1.2E-52 T 29-03-2018 CXR48_RS14690 662e9943c27e569408614d511e414b39 510 SUPERFAMILY SSF52540 3 224 9.21E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14690 662e9943c27e569408614d511e414b39 510 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS04120 aefec32679b4542560a3a8ebce280b37 397 Pfam PF07690 Major Facilitator Superfamily 15 335 8.4E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS04120 aefec32679b4542560a3a8ebce280b37 397 Gene3D G3DSA:1.20.1250.20 195 387 9.6E-14 T 29-03-2018 CXR48_RS04120 aefec32679b4542560a3a8ebce280b37 397 SUPERFAMILY SSF103473 8 382 4.71E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS04120 aefec32679b4542560a3a8ebce280b37 397 Gene3D G3DSA:1.20.1250.20 3 193 8.8E-31 T 29-03-2018 CXR48_RS16210 45798d3aab4b992d6fa184c0450d17f5 151 SMART SM00530 5 61 1.2E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS16210 45798d3aab4b992d6fa184c0450d17f5 151 Pfam PF08671 Anti-repressor SinI 123 148 2.3E-10 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CXR48_RS16210 45798d3aab4b992d6fa184c0450d17f5 151 Gene3D G3DSA:1.10.1660.10 88 148 0.33 T 29-03-2018 CXR48_RS16210 45798d3aab4b992d6fa184c0450d17f5 151 Gene3D G3DSA:1.10.260.40 1 75 1.2E-17 T 29-03-2018 CXR48_RS16210 45798d3aab4b992d6fa184c0450d17f5 151 SUPERFAMILY SSF47406 123 147 1.83E-5 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CXR48_RS16210 45798d3aab4b992d6fa184c0450d17f5 151 Pfam PF01381 Helix-turn-helix 6 61 3.5E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS16210 45798d3aab4b992d6fa184c0450d17f5 151 SUPERFAMILY SSF47413 2 65 2.28E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 Pfam PF00117 Glutamine amidotransferase class-I 165 340 2.3E-46 T 29-03-2018 IPR017926 Glutamine amidotransferase CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 342 6.0E-134 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00097 Anthranilate synthase component II signature 317 330 2.0E-7 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00097 Anthranilate synthase component II signature 204 213 2.0E-7 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00097 Anthranilate synthase component II signature 231 242 2.0E-7 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 SUPERFAMILY SSF52317 153 343 6.97E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 242 8.7E-12 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00096 Glutamine amidotransferase superfamily signature 204 213 8.7E-12 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00096 Glutamine amidotransferase superfamily signature 317 330 8.7E-12 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 128 3.4E-47 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 231 247 3.5E-33 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 248 265 3.5E-33 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 201 215 3.5E-33 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 273 284 3.5E-33 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 163 177 3.5E-33 T 29-03-2018 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 Gene3D G3DSA:3.40.50.880 135 347 1.1E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 Gene3D G3DSA:3.50.30.20 1 134 3.5E-51 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 346 42.414 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 SUPERFAMILY SSF52021 1 133 1.15E-47 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05505 8b67df05c43dc33a0af14d6b72d843ea 352 SMART SM01097 1 130 3.5E-69 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 PIRSF PIRSF000538 2 495 4.9E-182 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 SUPERFAMILY SSF53067 4 254 3.34E-100 T 29-03-2018 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 493 9.4E-228 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 251 2.3E-95 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 SUPERFAMILY SSF53067 254 492 1.24E-86 T 29-03-2018 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 59.556 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 Gene3D G3DSA:3.30.420.40 248 496 4.6E-80 T 29-03-2018 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 Gene3D G3DSA:3.30.420.40 1 247 7.2E-90 T 29-03-2018 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS04630 547bf9813dbf5ee938aedc203919c1c7 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 449 1.8E-65 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.0E-75 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 1.0E-75 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 1.0E-75 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 1.0E-75 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.0E-75 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.0E-75 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 1.0E-75 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 1.0E-75 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 1.0E-75 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 SUPERFAMILY SSF55424 346 468 1.01E-41 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 2.3E-43 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 2.3E-43 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.3E-43 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 2.3E-43 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 2.3E-43 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 468 7.0E-183 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 Gene3D G3DSA:3.40.50.720 9 43 0.038 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 Gene3D G3DSA:3.30.390.30 336 463 3.4E-41 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 457 4.0E-38 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 SUPERFAMILY SSF51905 7 339 7.62E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 330 7.2E-75 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 PIRSF PIRSF000350 3 459 6.3E-99 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 Gene3D G3DSA:1.10.287.990 44 109 1.5E-24 T 29-03-2018 CXR48_RS07280 ba090e8c98acbd816aece914da95c932 470 Gene3D G3DSA:3.40.50.720 157 335 3.9E-38 T 29-03-2018 CXR48_RS13665 5bfb0c782682a53444125615ae0273d6 207 Gene3D G3DSA:1.10.10.60 1 62 4.3E-15 T 29-03-2018 CXR48_RS13665 5bfb0c782682a53444125615ae0273d6 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS13665 5bfb0c782682a53444125615ae0273d6 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS13665 5bfb0c782682a53444125615ae0273d6 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CXR48_RS13665 5bfb0c782682a53444125615ae0273d6 207 SUPERFAMILY SSF46689 4 73 1.9E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS13665 5bfb0c782682a53444125615ae0273d6 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 7.7E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS13665 5bfb0c782682a53444125615ae0273d6 207 Gene3D G3DSA:1.10.357.10 63 199 1.5E-8 T 29-03-2018 CXR48_RS01925 e2e4487f51acc4e3037c7686d7a2f15f 227 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS01925 e2e4487f51acc4e3037c7686d7a2f15f 227 Pfam PF00005 ABC transporter 22 167 3.5E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS01925 e2e4487f51acc4e3037c7686d7a2f15f 227 SMART SM00382 30 216 1.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS01925 e2e4487f51acc4e3037c7686d7a2f15f 227 Gene3D G3DSA:3.40.50.300 1 226 2.2E-55 T 29-03-2018 CXR48_RS01925 e2e4487f51acc4e3037c7686d7a2f15f 227 SUPERFAMILY SSF52540 18 216 3.17E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.2E-10 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.2E-10 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 SMART SM01134 74 233 7.6E-62 T 29-03-2018 CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 SUPERFAMILY SSF46785 4 70 2.46E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 Gene3D G3DSA:1.10.10.10 1 67 9.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 Gene3D G3DSA:3.40.50.1360 75 239 3.5E-31 T 29-03-2018 CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 SUPERFAMILY SSF100950 76 232 1.33E-28 T 29-03-2018 CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 2.4E-19 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 Pfam PF00455 DeoR C terminal sensor domain 76 231 6.0E-46 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CXR48_RS05965 27fcaa104f2818dc96caf28ccd02dbf7 253 SMART SM00420 6 58 7.4E-21 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 SMART SM00155 312 339 3.6E-6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 SMART SM00155 141 168 6.8E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 Gene3D G3DSA:3.30.870.10 23 212 2.8E-29 T 29-03-2018 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 SUPERFAMILY SSF56024 42 217 2.26E-40 T 29-03-2018 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 37 396 6.3E-94 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 Pfam PF13091 PLD-like domain 241 365 9.0E-26 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 Pfam PF13091 PLD-like domain 61 171 6.2E-12 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 SUPERFAMILY SSF56024 232 382 2.69E-37 T 29-03-2018 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 PIRSF PIRSF000850 22 206 0.003 T 29-03-2018 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 PIRSF PIRSF000850 231 297 0.002 T 29-03-2018 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 PIRSF PIRSF000850 292 381 0.15 T 29-03-2018 CXR48_RS17585 ef1c79fc4134451983f587050faa7e72 399 Gene3D G3DSA:3.30.870.10 223 389 9.1E-28 T 29-03-2018 CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 Pfam PF13575 Domain of unknown function (DUF4135) 119 485 1.5E-88 T 29-03-2018 IPR025410 Lantibiotic biosynthesis protein, dehydration domain CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 SMART SM01260 604 959 6.0E-37 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 Pfam PF05147 Lanthionine synthetase C-like protein 605 954 3.9E-56 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 PRINTS PR01950 LanC-like protein superfamily signature 825 845 9.7E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 PRINTS PR01950 LanC-like protein superfamily signature 607 625 9.7E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 PRINTS PR01950 LanC-like protein superfamily signature 932 949 9.7E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 PRINTS PR01950 LanC-like protein superfamily signature 764 780 9.7E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 PRINTS PR01950 LanC-like protein superfamily signature 873 886 9.7E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 PRINTS PR01950 LanC-like protein superfamily signature 705 720 9.7E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 PIRSF PIRSF037228 1 961 5.2E-181 T 29-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 SUPERFAMILY SSF158745 581 957 7.45E-58 T 29-03-2018 CXR48_RS06150 3da200af2504fdea84a927dafbe1b250 961 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 30 951 3.1E-201 T 29-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 Gene3D G3DSA:1.10.287.950 217 430 6.7E-42 T 29-03-2018 CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 319 348 3.3E-15 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 317 3.3E-15 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 SMART SM00283 192 425 2.7E-23 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 Gene3D G3DSA:1.10.490.10 7 183 1.7E-34 T 29-03-2018 CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 Pfam PF11563 Protoglobin 30 182 5.7E-42 T 29-03-2018 CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 244 419 1.0E-33 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 SUPERFAMILY SSF58104 198 428 2.09E-50 T 29-03-2018 CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 SUPERFAMILY SSF58104 136 160 2.09E-50 T 29-03-2018 CXR48_RS05165 2dd80b1f2f3851984e40ccddb0ca29c7 430 SUPERFAMILY SSF46458 19 175 2.37E-40 T 29-03-2018 IPR009050 Globin-like CXR48_RS11980 1547c576ab08a955f37828a82d50e646 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS11980 1547c576ab08a955f37828a82d50e646 260 Gene3D G3DSA:3.40.50.300 2 258 2.2E-59 T 29-03-2018 CXR48_RS11980 1547c576ab08a955f37828a82d50e646 260 Pfam PF00005 ABC transporter 29 185 4.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS11980 1547c576ab08a955f37828a82d50e646 260 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 14 260 3.2E-120 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CXR48_RS11980 1547c576ab08a955f37828a82d50e646 260 SMART SM00382 38 231 3.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS11980 1547c576ab08a955f37828a82d50e646 260 SUPERFAMILY SSF52540 11 250 7.29E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 Pfam PF00202 Aminotransferase class-III 11 377 5.5E-126 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 378 1.4E-157 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 Gene3D G3DSA:3.90.1150.10 275 380 2.0E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 378 45.165 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 Gene3D G3DSA:3.40.640.10 151 274 4.5E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 PIRSF PIRSF000521 3 111 5.8E-5 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 PIRSF PIRSF000521 157 380 4.3E-33 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 PIRSF PIRSF000521 106 147 0.022 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 205 242 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 SUPERFAMILY SSF53383 4 378 2.11E-121 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS05500 a6e494cb0a8cd39d3d84d9e069ee349e 385 Gene3D G3DSA:3.90.1150.10 1 149 4.4E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS13255 137864c911f9448ed52d9d3a8bd6751a 442 Pfam PF13183 4Fe-4S dicluster domain 23 92 1.0E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CXR48_RS13255 137864c911f9448ed52d9d3a8bd6751a 442 SUPERFAMILY SSF46548 14 107 9.42E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CXR48_RS13255 137864c911f9448ed52d9d3a8bd6751a 442 Gene3D G3DSA:3.30.70.20 5 32 0.24 T 29-03-2018 CXR48_RS13255 137864c911f9448ed52d9d3a8bd6751a 442 Pfam PF02754 Cysteine-rich domain 199 280 1.7E-19 T 29-03-2018 IPR004017 Cysteine-rich domain CXR48_RS13255 137864c911f9448ed52d9d3a8bd6751a 442 Pfam PF02754 Cysteine-rich domain 329 414 3.7E-17 T 29-03-2018 IPR004017 Cysteine-rich domain CXR48_RS13255 137864c911f9448ed52d9d3a8bd6751a 442 PIRSF PIRSF000139 6 440 1.2E-136 T 29-03-2018 CXR48_RS13255 137864c911f9448ed52d9d3a8bd6751a 442 Gene3D G3DSA:3.30.70.20 85 381 4.2E-5 T 29-03-2018 CXR48_RS13255 137864c911f9448ed52d9d3a8bd6751a 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CXR48_RS13255 137864c911f9448ed52d9d3a8bd6751a 442 Gene3D G3DSA:3.30.70.20 33 84 1.1E-8 T 29-03-2018 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1790 1806 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Gene3D G3DSA:3.40.50.720 1264 1515 3.9E-30 T 29-03-2018 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Gene3D G3DSA:3.40.47.10 1892 2049 2.9E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Gene3D G3DSA:3.40.47.10 714 884 1.5E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SUPERFAMILY SSF47336 332 400 2.88E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SUPERFAMILY SSF53901 1643 1989 1.84E-66 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1564 1579 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 450 699 7.8E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1645 1877 9.5E-58 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Gene3D G3DSA:1.10.1200.10 1530 1642 1.0E-17 T 29-03-2018 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SUPERFAMILY SSF51735 1268 1520 7.3E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Gene3D G3DSA:3.10.129.10 44 163 7.8E-11 T 29-03-2018 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Gene3D G3DSA:3.40.47.10 1643 1889 4.6E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 828 952 1.2E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Pfam PF08659 KR domain 1272 1462 1.2E-34 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SMART SM00825 Beta-ketoacyl synthase 452 886 2.8E-193 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SMART SM00825 Beta-ketoacyl synthase 1647 2051 8.1E-103 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SMART SM00823 Phosphopantetheine attachment site 1538 1609 3.0E-11 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SMART SM00823 Phosphopantetheine attachment site 330 400 0.0083 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 707 824 4.3E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1885 1998 3.4E-31 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SUPERFAMILY SSF47336 1535 1659 1.31E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SUPERFAMILY SSF51735 1130 1253 1.38E-6 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Gene3D G3DSA:1.10.1200.10 310 406 1.2E-6 T 29-03-2018 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1269 1463 1.7E-31 T 29-03-2018 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SMART SM00826 42 203 0.0095 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Pfam PF14765 Polyketide synthase dehydratase 42 309 1.9E-26 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SMART SM01294 1539 1605 1.7E-6 T 29-03-2018 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Gene3D G3DSA:3.40.47.10 442 710 6.0E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SUPERFAMILY SSF53901 448 817 8.89E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 SUPERFAMILY SSF53901 862 880 8.89E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Pfam PF00550 Phosphopantetheine attachment site 332 395 9.3E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11355 d5576ae25e682ed66b8e5a1275d345f0 2098 Pfam PF00550 Phosphopantetheine attachment site 1539 1605 6.7E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SMART SM01294 3046 3109 0.0084 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.40.50.980 2702 2849 7.7E-27 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.40.50.980 608 773 1.4E-32 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.40.50.980 1659 1815 1.6E-29 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.30.559.10 2089 2288 4.8E-38 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.30.559.10 1049 1249 9.0E-44 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF52777 8 185 1.45E-28 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF56801 424 989 1.83E-149 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:1.10.1200.10 2022 2088 8.1E-23 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.40.50.980 1503 1658 1.2E-43 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.40.50.980 2542 2701 1.6E-47 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.40.50.980 458 607 3.7E-46 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.30.300.30 2934 3048 6.3E-40 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.30.300.30 862 982 1.4E-39 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.30.300.30 1903 2021 9.0E-41 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF56801 1470 2028 6.02E-151 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF52777 191 429 1.22E-41 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:1.10.1200.10 3049 3111 4.6E-22 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF47336 969 1041 1.21E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:1.10.1200.10 983 1048 7.8E-21 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF56801 2510 3058 8.5E-152 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00550 Phosphopantetheine attachment site 2018 2081 5.2E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00550 Phosphopantetheine attachment site 3048 3109 1.9E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00550 Phosphopantetheine attachment site 979 1041 2.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1001 1016 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00501 AMP-binding enzyme 1512 1908 2.6E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00501 AMP-binding enzyme 2551 2939 2.0E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00501 AMP-binding enzyme 466 867 1.7E-102 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF47336 3038 3110 7.2E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF52777 3119 3293 2.22E-34 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.30.559.10 3112 3309 3.0E-27 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2040 2055 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3427 3580 1.2E-50 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SMART SM00823 Phosphopantetheine attachment site 3045 3113 5.2E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SMART SM00823 Phosphopantetheine attachment site 977 1046 0.0014 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SMART SM00823 Phosphopantetheine attachment site 2016 2085 0.012 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:3.30.559.10 2 194 1.5E-21 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 ProSitePatterns PS00455 Putative AMP-binding domain signature. 602 613 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2572 2963 1.6E-121 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 487 891 2.4E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1533 1932 1.4E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2696 2707 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:2.30.38.10 777 857 1.8E-23 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:2.30.38.10 2850 2929 1.1E-21 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:2.30.38.10 1818 1898 3.0E-24 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF52777 2272 2519 5.89E-58 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Gene3D G3DSA:1.10.1220.10 1259 1314 0.0076 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF47336 2008 2113 3.14E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF52777 2099 2266 5.11E-40 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00668 Condensation domain 3123 3572 1.4E-122 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00668 Condensation domain 1060 1488 3.1E-142 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00668 Condensation domain 4 446 5.6E-111 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF00668 Condensation domain 2098 2531 3.2E-139 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1653 1664 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF52777 1234 1475 2.67E-64 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF52777 1058 1247 2.33E-44 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3069 3084 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 SUPERFAMILY SSF52777 3308 3556 9.67E-37 T 29-03-2018 CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF13193 AMP-binding enzyme C-terminal domain 2947 3019 2.5E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF13193 AMP-binding enzyme C-terminal domain 1916 1989 2.5E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01785 cf78d1f00fc5949d4d75015b56567a63 3584 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 950 7.7E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Gene3D G3DSA:3.30.230.70 13 246 8.1E-58 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 SUPERFAMILY SSF54211 293 488 1.16E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Pfam PF00575 S1 RNA binding domain 620 691 5.3E-19 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 SUPERFAMILY SSF55666 145 235 1.7E-31 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 SMART SM00322 553 618 1.8E-13 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 31.178 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Pfam PF00013 KH domain 557 615 2.8E-10 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Gene3D G3DSA:3.30.230.70 309 564 5.0E-61 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 SUPERFAMILY SSF54791 556 641 6.83E-24 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Gene3D G3DSA:2.40.50.140 618 699 6.1E-24 T 29-03-2018 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 693 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 2.7E-16 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Pfam PF03725 3' exoribonuclease family, domain 2 460 530 1.0E-7 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 SUPERFAMILY SSF50249 621 704 1.86E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Gene3D G3DSA:3.30.1370.10 565 617 1.1E-14 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 241 320 2.0E-19 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Gene3D G3DSA:1.10.10.400 247 308 9.1E-22 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 SUPERFAMILY SSF55666 454 561 2.66E-28 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 3.1E-18 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 1.5E-19 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 SUPERFAMILY SSF54211 7 144 1.72E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 PIRSF PIRSF005499 2 707 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CXR48_RS08325 2e05675536937d9d903a427ddba8bad2 707 SMART SM00316 621 691 1.3E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 263 931 3.0E-256 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 SUPERFAMILY SSF50692 795 933 3.94E-33 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Gene3D G3DSA:2.40.40.20 782 933 1.0E-24 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 SUPERFAMILY SSF54292 6 74 1.57E-15 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Gene3D G3DSA:2.20.25.90 268 313 8.8E-18 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 6 75 1.7E-12 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Gene3D G3DSA:3.40.228.10 425 504 2.3E-15 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Gene3D G3DSA:3.30.70.20 152 196 6.6E-11 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Gene3D G3DSA:3.30.70.20 197 267 0.065 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 SMART SM00929 84 125 2.3E-9 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 SUPERFAMILY SSF53706 252 775 4.97E-195 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Gene3D G3DSA:3.40.50.740 315 424 2.8E-27 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 123 2.4E-8 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Gene3D G3DSA:3.30.70.20 108 151 0.031 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 191 202 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Gene3D G3DSA:3.40.50.740 506 781 5.8E-78 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 SUPERFAMILY SSF54862 77 211 2.05E-29 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Gene3D G3DSA:3.10.20.30 3 107 3.5E-10 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 258 312 2.2E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Pfam PF00384 Molybdopterin oxidoreductase 315 738 7.2E-76 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Pfam PF01568 Molydopterin dinucleotide binding domain 823 928 7.5E-21 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 SMART SM00926 258 312 9.2E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 PIRSF PIRSF036643 1 965 0.0 T 29-03-2018 CXR48_RS06015 3ddd80b0e8a3d28b19202e9fcc89519e 985 Pfam PF12838 4Fe-4S dicluster domain 147 205 2.7E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CXR48_RS08930 0fcfaf94a7793af6ae2618265725c7f9 48 Pfam PF08179 Small acid-soluble spore protein P family 1 43 4.1E-24 T 29-03-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 CXR48_RS08930 0fcfaf94a7793af6ae2618265725c7f9 48 Hamap MF_00666 Small, acid-soluble spore protein P [sspP]. 1 48 19.711 T 29-03-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 CXR48_RS14180 7aea160617a715e9c597fa39ae98333a 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 1.0E-14 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CXR48_RS14180 7aea160617a715e9c597fa39ae98333a 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 1.0E-14 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CXR48_RS14180 7aea160617a715e9c597fa39ae98333a 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 1.0E-14 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CXR48_RS14180 7aea160617a715e9c597fa39ae98333a 145 SUPERFAMILY SSF47240 3 145 1.13E-46 T 29-03-2018 IPR009078 Ferritin-like superfamily CXR48_RS14180 7aea160617a715e9c597fa39ae98333a 145 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CXR48_RS14180 7aea160617a715e9c597fa39ae98333a 145 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CXR48_RS14180 7aea160617a715e9c597fa39ae98333a 145 PIRSF PIRSF005900 1 145 3.9E-46 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CXR48_RS14180 7aea160617a715e9c597fa39ae98333a 145 Pfam PF00210 Ferritin-like domain 7 145 6.7E-32 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CXR48_RS14180 7aea160617a715e9c597fa39ae98333a 145 Gene3D G3DSA:1.20.1260.10 1 145 3.9E-47 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS13530 b2b9f93d891e96997ae08cb27e376195 113 Pfam PF14034 Sporulation protein YtrH 10 108 7.6E-42 T 29-03-2018 IPR025689 Sporulation protein YtrH CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 SMART SM00382 193 332 1.3E-23 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 109 601 1.6E-248 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 Pfam PF01434 Peptidase family M41 391 600 4.5E-90 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 Gene3D G3DSA:3.40.50.300 423 591 0.039 T 29-03-2018 CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 197 329 5.8E-44 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 ProSitePatterns PS00674 AAA-protein family signature. 300 318 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 SUPERFAMILY SSF52540 151 401 2.02E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 SUPERFAMILY SSF140990 411 607 4.58E-74 T 29-03-2018 CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 Gene3D G3DSA:1.10.8.60 346 418 1.6E-23 T 29-03-2018 CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 Pfam PF06480 FtsH Extracellular 9 99 3.2E-11 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 Gene3D G3DSA:3.40.50.300 135 345 1.6E-63 T 29-03-2018 CXR48_RS00420 20597ffc09c038af1bd563e86e6a5087 639 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 609 38.76 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CXR48_RS17465 6c6efbf6a63b2319838c31d6b0c48489 185 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 7 185 22.244 T 29-03-2018 IPR022929 Putative manganese efflux pump MntP CXR48_RS17465 6c6efbf6a63b2319838c31d6b0c48489 185 Pfam PF02659 Putative manganese efflux pump 35 182 1.0E-39 T 29-03-2018 IPR003810 Putative manganese efflux pump CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 Gene3D G3DSA:3.30.200.20 2 78 3.4E-21 T 29-03-2018 CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 SUPERFAMILY SSF56112 8 267 4.99E-84 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 Pfam PF03793 PASTA domain 495 556 7.4E-13 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 Pfam PF03793 PASTA domain 431 489 1.5E-14 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 Pfam PF03793 PASTA domain 358 419 2.1E-11 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 SMART SM00220 11 271 4.4E-78 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 Pfam PF00069 Protein kinase domain 11 260 3.2E-56 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 Gene3D G3DSA:1.10.510.10 79 461 7.6E-59 T 29-03-2018 CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 SMART SM00740 423 490 3.9E-14 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 SMART SM00740 491 557 9.1E-17 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 SMART SM00740 354 422 2.5E-16 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07860 60d85d2a01f6efc54d60070b8977f01d 647 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CXR48_RS10615 1e43983be07e0314eccc4c3414e296df 127 Pfam PF02261 Aspartate decarboxylase 1 114 1.4E-54 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CXR48_RS10615 1e43983be07e0314eccc4c3414e296df 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 98 3.0E-47 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CXR48_RS10615 1e43983be07e0314eccc4c3414e296df 127 PIRSF PIRSF006246 1 126 6.8E-56 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CXR48_RS10615 1e43983be07e0314eccc4c3414e296df 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 126 1.1E-67 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CXR48_RS10615 1e43983be07e0314eccc4c3414e296df 127 SUPERFAMILY SSF50692 1 117 3.23E-51 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CXR48_RS10615 1e43983be07e0314eccc4c3414e296df 127 Gene3D G3DSA:2.40.40.20 1 117 5.3E-56 T 29-03-2018 CXR48_RS10615 1e43983be07e0314eccc4c3414e296df 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 75.116 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CXR48_RS09785 49a0c53ea41ff81e92f83cefea3a7b08 290 Pfam PF00583 Acetyltransferase (GNAT) family 168 239 3.2E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS09785 49a0c53ea41ff81e92f83cefea3a7b08 290 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 17 280 1.4E-91 T 29-03-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 CXR48_RS09785 49a0c53ea41ff81e92f83cefea3a7b08 290 Gene3D G3DSA:3.40.630.30 34 95 0.067 T 29-03-2018 CXR48_RS09785 49a0c53ea41ff81e92f83cefea3a7b08 290 SUPERFAMILY SSF55729 130 280 5.14E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS09785 49a0c53ea41ff81e92f83cefea3a7b08 290 Gene3D G3DSA:3.40.630.30 124 289 6.1E-15 T 29-03-2018 CXR48_RS00435 cd25977feff2a3c8caa5d1bfc12597e1 296 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 182 203 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CXR48_RS00435 cd25977feff2a3c8caa5d1bfc12597e1 296 SUPERFAMILY SSF109998 37 182 1.18E-23 T 29-03-2018 IPR027304 Trigger factor/SurA domain CXR48_RS00435 cd25977feff2a3c8caa5d1bfc12597e1 296 Pfam PF13624 SurA N-terminal domain 5 127 5.1E-7 T 29-03-2018 CXR48_RS00435 cd25977feff2a3c8caa5d1bfc12597e1 296 SUPERFAMILY SSF54534 146 245 3.06E-18 T 29-03-2018 CXR48_RS00435 cd25977feff2a3c8caa5d1bfc12597e1 296 Pfam PF13145 PPIC-type PPIASE domain 134 259 7.7E-18 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CXR48_RS00435 cd25977feff2a3c8caa5d1bfc12597e1 296 Gene3D G3DSA:1.10.4030.10 30 132 3.0E-8 T 29-03-2018 CXR48_RS00435 cd25977feff2a3c8caa5d1bfc12597e1 296 Gene3D G3DSA:3.10.50.40 145 271 8.6E-27 T 29-03-2018 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 3.6E-114 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 44.277 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 158 175 2.6E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 196 210 2.6E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.6E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.6E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.6E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 175 186 2.6E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 Pfam PF00318 Ribosomal protein S2 9 224 1.8E-102 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 SUPERFAMILY SSF52313 6 231 2.22E-101 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CXR48_RS08225 26dd73881c440a2e75ab5dc2e1b7bfaa 246 Gene3D G3DSA:3.40.50.10490 5 246 2.3E-106 T 29-03-2018 CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 SMART SM00345 16 74 8.9E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 Pfam PF07729 FCD domain 84 208 1.4E-23 T 29-03-2018 IPR011711 GntR, C-terminal CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 SUPERFAMILY SSF48008 79 217 6.54E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 SMART SM00895 84 209 3.8E-16 T 29-03-2018 IPR011711 GntR, C-terminal CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 Gene3D G3DSA:1.20.120.530 84 225 1.1E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 Gene3D G3DSA:1.10.10.10 3 83 2.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 3.7E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02895 250c001b4e60dc4f306bd8196e9c2428 228 SUPERFAMILY SSF46785 6 78 1.73E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 Pfam PF00813 FliP family 25 217 3.0E-82 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 143 155 2.5E-26 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 81 93 2.5E-26 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 211 221 2.5E-26 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 21 30 2.5E-26 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 93 107 2.5E-26 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 121 133 2.5E-26 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 25 221 3.3E-94 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 150 165 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 23 42 1.9E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 171 192 1.9E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 150 170 1.9E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 1.9E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 42 62 1.9E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 220 1.9E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CXR48_RS08155 3cfcfb96bc69136a79ba7ef4f56c1725 221 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 198 210 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CXR48_RS13080 652e3ab0511e5e342ce31503fc6ff2c4 169 SUPERFAMILY SSF56300 1 155 8.29E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS13080 652e3ab0511e5e342ce31503fc6ff2c4 169 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 145 5.8E-37 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CXR48_RS13080 652e3ab0511e5e342ce31503fc6ff2c4 169 Gene3D G3DSA:3.60.21.10 1 168 2.8E-22 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS13080 652e3ab0511e5e342ce31503fc6ff2c4 169 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 145 9.5E-30 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 491 5.8E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 Gene3D G3DSA:3.40.50.980 153 308 4.5E-36 T 29-03-2018 CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 SUPERFAMILY SSF56801 3 500 3.92E-119 T 29-03-2018 CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 28 428 2.1E-101 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 148 159 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 Gene3D G3DSA:3.30.300.30 397 502 6.9E-26 T 29-03-2018 CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 2 501 2.3E-229 T 29-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 Gene3D G3DSA:3.40.50.980 2 152 3.7E-31 T 29-03-2018 CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 Gene3D G3DSA:2.30.38.10 309 396 1.2E-20 T 29-03-2018 CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 Pfam PF00501 AMP-binding enzyme 10 403 2.2E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS18235 cc58b7a2a48c4da240491a3b92f26077 503 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 503 237.917 T 29-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CXR48_RS17210 67c74c8b41e06c0e7064bd49c7533f0a 265 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 185 260 5.8E-17 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CXR48_RS17210 67c74c8b41e06c0e7064bd49c7533f0a 265 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CXR48_RS17210 67c74c8b41e06c0e7064bd49c7533f0a 265 SUPERFAMILY SSF117143 110 223 1.44E-8 T 29-03-2018 CXR48_RS17210 67c74c8b41e06c0e7064bd49c7533f0a 265 Pfam PF00460 Flagella basal body rod protein 5 35 4.3E-13 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CXR48_RS10160 788243d78c0bbc1351c441fb612ca738 366 PIRSF PIRSF000451 1 364 3.4E-125 T 29-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 CXR48_RS10160 788243d78c0bbc1351c441fb612ca738 366 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 2 205 7.6E-20 T 29-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal CXR48_RS10160 788243d78c0bbc1351c441fb612ca738 366 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 223 358 4.2E-19 T 29-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal CXR48_RS10160 788243d78c0bbc1351c441fb612ca738 366 Gene3D G3DSA:3.40.47.10 1 209 6.3E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS10160 788243d78c0bbc1351c441fb612ca738 366 Gene3D G3DSA:3.40.47.10 219 364 1.5E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS10160 788243d78c0bbc1351c441fb612ca738 366 SUPERFAMILY SSF53901 1 207 5.28E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS10160 788243d78c0bbc1351c441fb612ca738 366 SUPERFAMILY SSF53901 219 361 9.21E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS10665 3fc4ceb88fcd69d656db7fd52405ee57 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 222 276 3.9E-23 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CXR48_RS10665 3fc4ceb88fcd69d656db7fd52405ee57 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 217 5.6E-65 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS10665 3fc4ceb88fcd69d656db7fd52405ee57 290 PIRSF PIRSF006483 1 284 2.3E-100 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS18880 5ed2be9ac2f728544bc356740d8f1ce9 771 SUPERFAMILY SSF52540 169 206 5.32E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18880 5ed2be9ac2f728544bc356740d8f1ce9 771 SUPERFAMILY SSF52540 70 99 5.32E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18880 5ed2be9ac2f728544bc356740d8f1ce9 771 SUPERFAMILY SSF52540 473 751 5.32E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18880 5ed2be9ac2f728544bc356740d8f1ce9 771 SUPERFAMILY SSF52540 2 40 5.32E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18880 5ed2be9ac2f728544bc356740d8f1ce9 771 Gene3D G3DSA:3.40.50.300 587 767 5.0E-21 T 29-03-2018 CXR48_RS18880 5ed2be9ac2f728544bc356740d8f1ce9 771 Pfam PF13086 AAA domain 2 534 3.2E-8 T 29-03-2018 CXR48_RS18880 5ed2be9ac2f728544bc356740d8f1ce9 771 Gene3D G3DSA:3.40.50.300 1 532 3.9E-20 T 29-03-2018 CXR48_RS18880 5ed2be9ac2f728544bc356740d8f1ce9 771 Pfam PF13087 AAA domain 614 749 2.7E-15 T 29-03-2018 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 Hamap MF_00318 Enolase [eno]. 2 413 46.008 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 Gene3D G3DSA:3.20.20.120 128 430 2.2E-107 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 Pfam PF03952 Enolase, N-terminal domain 4 134 4.9E-63 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 SMART SM01192 139 427 4.0E-229 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 PRINTS PR00148 Enolase signature 313 324 6.7E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 PRINTS PR00148 Enolase signature 336 350 6.7E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 PRINTS PR00148 Enolase signature 161 174 6.7E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 PRINTS PR00148 Enolase signature 37 51 6.7E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 PRINTS PR00148 Enolase signature 107 123 6.7E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 PRINTS PR00148 Enolase signature 365 382 6.7E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 SUPERFAMILY SSF51604 139 428 1.13E-130 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 SMART SM01193 4 134 3.6E-101 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 PIRSF PIRSF001400 1 427 5.1E-198 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 Gene3D G3DSA:3.30.390.10 3 126 1.5E-56 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 427 5.0E-224 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 ProSitePatterns PS00164 Enolase signature. 336 349 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 426 3.2E-145 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16010 4b437ffed5aa0501b9f9d3e90886ec27 430 SUPERFAMILY SSF54826 3 138 1.92E-61 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS14790 da467873ad4c89ca8884e79643d3059c 183 Gene3D G3DSA:3.40.50.850 1 183 7.2E-51 T 29-03-2018 CXR48_RS14790 da467873ad4c89ca8884e79643d3059c 183 Pfam PF00857 Isochorismatase family 4 181 2.3E-39 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS14790 da467873ad4c89ca8884e79643d3059c 183 SUPERFAMILY SSF52499 2 181 2.75E-52 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS19015 c351cba13c705d44c659665788052a92 279 Pfam PF09648 YycH protein 35 267 9.9E-61 T 29-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 CXR48_RS07345 9e1c0c1785c345aecc38f2b9de814be9 97 Pfam PF13490 Putative zinc-finger 6 36 1.3E-5 T 29-03-2018 IPR027383 Putative zinc-finger CXR48_RS06900 1566d29ac6be6a4c452b34cc31204044 288 PIRSF PIRSF000103 1 287 3.3E-71 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CXR48_RS06900 1566d29ac6be6a4c452b34cc31204044 288 SUPERFAMILY SSF51735 3 164 3.65E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS06900 1566d29ac6be6a4c452b34cc31204044 288 Gene3D G3DSA:1.10.1040.10 174 288 1.7E-34 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS06900 1566d29ac6be6a4c452b34cc31204044 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 161 2.4E-53 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CXR48_RS06900 1566d29ac6be6a4c452b34cc31204044 288 Gene3D G3DSA:3.40.50.720 1 173 6.4E-36 T 29-03-2018 CXR48_RS06900 1566d29ac6be6a4c452b34cc31204044 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 286 2.4E-35 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CXR48_RS06900 1566d29ac6be6a4c452b34cc31204044 288 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CXR48_RS06900 1566d29ac6be6a4c452b34cc31204044 288 SUPERFAMILY SSF48179 164 286 1.7E-38 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS14210 80e7fcada051d8c8850d4008867f1098 82 Pfam PF01197 Ribosomal protein L31 1 79 2.6E-26 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS14210 80e7fcada051d8c8850d4008867f1098 82 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 2.6E-18 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS14210 80e7fcada051d8c8850d4008867f1098 82 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS14210 80e7fcada051d8c8850d4008867f1098 82 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 23.877 T 29-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS14210 80e7fcada051d8c8850d4008867f1098 82 PRINTS PR01249 Ribosomal protein L31 signature 2 19 4.9E-17 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS14210 80e7fcada051d8c8850d4008867f1098 82 PRINTS PR01249 Ribosomal protein L31 signature 60 78 4.9E-17 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS14210 80e7fcada051d8c8850d4008867f1098 82 PRINTS PR01249 Ribosomal protein L31 signature 45 60 4.9E-17 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS14210 80e7fcada051d8c8850d4008867f1098 82 SUPERFAMILY SSF143800 1 80 2.24E-22 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 5 910 5.6E-245 T 29-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 SUPERFAMILY SSF52540 671 890 3.06E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 SUPERFAMILY SSF52540 272 325 3.06E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 SUPERFAMILY SSF52540 412 482 3.06E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 SMART SM00487 253 525 0.0044 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 Gene3D G3DSA:3.40.50.300 724 897 9.4E-12 T 29-03-2018 CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 Gene3D G3DSA:3.40.50.300 255 696 3.3E-26 T 29-03-2018 CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 Pfam PF13307 Helicase C-terminal domain 751 908 1.8E-36 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 Gene3D G3DSA:3.30.420.10 1 156 1.5E-39 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 SMART SM00491 762 896 2.0E-45 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 Pfam PF00929 Exonuclease 7 161 1.3E-37 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 SMART SM00479 5 172 8.6E-51 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 SUPERFAMILY SSF53098 5 195 1.96E-55 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 Pfam PF04851 Type III restriction enzyme, res subunit 256 468 3.2E-6 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 Gene3D G3DSA:1.20.5.140 157 173 6.9E-4 T 29-03-2018 CXR48_RS10610 e29009cf84b0e6bb63322a44b18a1267 928 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 2 172 1.5E-29 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS15305 ee0f591980d678f1f81b8116732334c0 341 Gene3D G3DSA:3.30.70.260 260 340 4.3E-26 T 29-03-2018 CXR48_RS15305 ee0f591980d678f1f81b8116732334c0 341 Pfam PF00005 ABC transporter 22 169 2.8E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15305 ee0f591980d678f1f81b8116732334c0 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15305 ee0f591980d678f1f81b8116732334c0 341 Pfam PF09383 NIL domain 266 337 6.4E-21 T 29-03-2018 IPR018449 NIL domain CXR48_RS15305 ee0f591980d678f1f81b8116732334c0 341 SMART SM00930 263 338 3.9E-28 T 29-03-2018 IPR018449 NIL domain CXR48_RS15305 ee0f591980d678f1f81b8116732334c0 341 SMART SM00382 30 218 1.8E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15305 ee0f591980d678f1f81b8116732334c0 341 SUPERFAMILY SSF55021 249 340 4.01E-23 T 29-03-2018 CXR48_RS15305 ee0f591980d678f1f81b8116732334c0 341 Gene3D G3DSA:3.40.50.300 1 259 1.0E-79 T 29-03-2018 CXR48_RS15305 ee0f591980d678f1f81b8116732334c0 341 SUPERFAMILY SSF52540 1 240 4.69E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS15185 ef70bedb07abbb4fe052e6e31aebffa8 368 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15185 ef70bedb07abbb4fe052e6e31aebffa8 368 Gene3D G3DSA:2.40.50.100 240 296 1.3E-11 T 29-03-2018 CXR48_RS15185 ef70bedb07abbb4fe052e6e31aebffa8 368 Gene3D G3DSA:2.40.50.140 297 351 4.2E-14 T 29-03-2018 CXR48_RS15185 ef70bedb07abbb4fe052e6e31aebffa8 368 Pfam PF08402 TOBE domain 286 359 7.7E-5 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CXR48_RS15185 ef70bedb07abbb4fe052e6e31aebffa8 368 SUPERFAMILY SSF52540 4 243 8.4E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS15185 ef70bedb07abbb4fe052e6e31aebffa8 368 SUPERFAMILY SSF50331 237 366 4.37E-26 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CXR48_RS15185 ef70bedb07abbb4fe052e6e31aebffa8 368 SMART SM00382 29 212 4.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15185 ef70bedb07abbb4fe052e6e31aebffa8 368 Gene3D G3DSA:3.40.50.300 1 237 5.5E-70 T 29-03-2018 CXR48_RS15185 ef70bedb07abbb4fe052e6e31aebffa8 368 Pfam PF00005 ABC transporter 21 162 3.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS00260 ce3129c929c62def93a38c3dab6da426 255 Gene3D G3DSA:3.20.20.140 1 255 1.4E-98 T 29-03-2018 CXR48_RS00260 ce3129c929c62def93a38c3dab6da426 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CXR48_RS00260 ce3129c929c62def93a38c3dab6da426 255 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CXR48_RS00260 ce3129c929c62def93a38c3dab6da426 255 SUPERFAMILY SSF51556 1 254 1.22E-98 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS00260 ce3129c929c62def93a38c3dab6da426 255 PIRSF PIRSF005902 1 255 5.6E-92 T 29-03-2018 IPR001130 TatD family GO:0016788 CXR48_RS00260 ce3129c929c62def93a38c3dab6da426 255 Pfam PF01026 TatD related DNase 3 252 4.0E-91 T 29-03-2018 IPR001130 TatD family GO:0016788 CXR48_RS00260 ce3129c929c62def93a38c3dab6da426 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CXR48_RS00260 ce3129c929c62def93a38c3dab6da426 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 2.1E-104 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CXR48_RS18340 2ca1b2a3264310333bdb2167abc6c899 293 Pfam PF00480 ROK family 3 282 1.1E-72 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CXR48_RS18340 2ca1b2a3264310333bdb2167abc6c899 293 Gene3D G3DSA:3.30.420.40 114 292 2.4E-41 T 29-03-2018 CXR48_RS18340 2ca1b2a3264310333bdb2167abc6c899 293 ProSitePatterns PS01125 ROK family signature. 128 153 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CXR48_RS18340 2ca1b2a3264310333bdb2167abc6c899 293 SUPERFAMILY SSF53067 3 283 6.48E-46 T 29-03-2018 CXR48_RS18340 2ca1b2a3264310333bdb2167abc6c899 293 Gene3D G3DSA:3.30.420.40 1 113 1.2E-19 T 29-03-2018 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 793 1.2E-270 T 29-03-2018 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Gene3D G3DSA:1.10.268.10 343 485 1.1E-48 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 599 5.8E-6 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 507 519 1.5 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 606 650 4.9E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 704 752 4.0E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 696 4.0E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Gene3D G3DSA:3.90.199.10 33 214 5.3E-77 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 SUPERFAMILY SSF101904 499 804 1.19E-96 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 7 744 0.0 T 29-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 SMART SM00434 10 463 3.8E-265 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 467 1.8E-152 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Gene3D G3DSA:3.30.1360.40 235 331 2.2E-33 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 6 802 33.26 T 29-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 Gene3D G3DSA:2.120.10.90 499 806 5.4E-89 T 29-03-2018 CXR48_RS08995 545ab3668e8ff932bf48c6d0ab8f06be 807 SUPERFAMILY SSF56719 30 485 1.7E-170 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CXR48_RS19260 fd5f54753f24e2a3895ff11610252cd1 213 SUPERFAMILY SSF52218 1 211 5.35E-43 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS19260 fd5f54753f24e2a3895ff11610252cd1 213 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 210 26.427 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CXR48_RS19260 fd5f54753f24e2a3895ff11610252cd1 213 Gene3D G3DSA:3.40.50.360 2 213 5.0E-30 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS19260 fd5f54753f24e2a3895ff11610252cd1 213 Pfam PF02525 Flavodoxin-like fold 3 205 1.0E-39 T 29-03-2018 IPR003680 Flavodoxin-like fold CXR48_RS10395 0c46b285b02a6c013a8acdb6de4efcca 233 Pfam PF07261 Replication initiation and membrane attachment 127 195 5.3E-10 T 29-03-2018 IPR006343 DnaD domain CXR48_RS10395 0c46b285b02a6c013a8acdb6de4efcca 233 Gene3D G3DSA:1.10.10.630 131 195 1.9E-9 T 29-03-2018 IPR034829 DnaD-like domain CXR48_RS10395 0c46b285b02a6c013a8acdb6de4efcca 233 SUPERFAMILY SSF158499 127 184 1.83E-8 T 29-03-2018 IPR006343 DnaD domain CXR48_RS10395 0c46b285b02a6c013a8acdb6de4efcca 233 Gene3D G3DSA:1.10.10.10 18 130 1.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10395 0c46b285b02a6c013a8acdb6de4efcca 233 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 127 184 1.7E-6 T 29-03-2018 IPR006343 DnaD domain CXR48_RS17545 c0179e067f28066cab1ee6ef852b5ce3 429 Gene3D G3DSA:3.65.10.10 21 217 1.6E-44 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CXR48_RS17545 c0179e067f28066cab1ee6ef852b5ce3 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 3.8E-97 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CXR48_RS17545 c0179e067f28066cab1ee6ef852b5ce3 429 Gene3D G3DSA:3.65.10.10 218 419 4.9E-47 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CXR48_RS17545 c0179e067f28066cab1ee6ef852b5ce3 429 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 2.4E-175 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS17545 c0179e067f28066cab1ee6ef852b5ce3 429 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 42.615 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS17545 c0179e067f28066cab1ee6ef852b5ce3 429 SUPERFAMILY SSF55205 1 415 4.74E-135 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CXR48_RS15260 46926922cd15a5e5237737694bced4ce 465 SUPERFAMILY SSF101960 32 462 2.48E-140 T 29-03-2018 CXR48_RS15260 46926922cd15a5e5237737694bced4ce 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 2.5E-74 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CXR48_RS15260 46926922cd15a5e5237737694bced4ce 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 6.0E-232 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CXR48_RS11245 5d79db72e1a419a7190e004bd45d611f 322 SUPERFAMILY SSF55729 5 138 1.15E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS11245 5d79db72e1a419a7190e004bd45d611f 322 SUPERFAMILY SSF81301 155 317 1.28E-55 T 29-03-2018 CXR48_RS11245 5d79db72e1a419a7190e004bd45d611f 322 Gene3D G3DSA:3.40.630.30 5 156 9.3E-16 T 29-03-2018 CXR48_RS11245 5d79db72e1a419a7190e004bd45d611f 322 Gene3D G3DSA:3.30.460.10 157 320 9.9E-64 T 29-03-2018 CXR48_RS11245 5d79db72e1a419a7190e004bd45d611f 322 Pfam PF04229 GrpB protein 154 312 3.4E-56 T 29-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CXR48_RS11245 5d79db72e1a419a7190e004bd45d611f 322 Pfam PF13673 Acetyltransferase (GNAT) domain 46 142 2.8E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 SUPERFAMILY SSF52540 307 507 6.26E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 Gene3D G3DSA:3.40.50.300 1 272 1.5E-55 T 29-03-2018 CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 Gene3D G3DSA:3.40.50.300 288 511 1.5E-39 T 29-03-2018 CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 Pfam PF00005 ABC transporter 20 191 2.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 Pfam PF00005 ABC transporter 342 469 4.4E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 SUPERFAMILY SSF52540 4 244 4.17E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 Pfam PF12848 ABC transporter 230 315 2.9E-21 T 29-03-2018 IPR032781 ABC-transporter extension domain CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 SMART SM00382 349 518 7.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 SMART SM00382 28 252 3.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03645 917315270d53f2a8410abe50fce0064a 518 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS00145 3d2bf26612ec4f8676f3ffe1cc54f30a 198 SMART SM00493 80 165 7.7E-20 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS00145 3d2bf26612ec4f8676f3ffe1cc54f30a 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CXR48_RS00145 3d2bf26612ec4f8676f3ffe1cc54f30a 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 112.436 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CXR48_RS00145 3d2bf26612ec4f8676f3ffe1cc54f30a 198 TIGRFAM TIGR00615 recR: recombination protein RecR 1 196 7.0E-92 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CXR48_RS00145 3d2bf26612ec4f8676f3ffe1cc54f30a 198 SUPERFAMILY SSF111304 1 198 1.96E-79 T 29-03-2018 IPR023627 Recombination protein RecR CXR48_RS00145 3d2bf26612ec4f8676f3ffe1cc54f30a 198 Pfam PF13662 Toprim domain 80 171 6.8E-26 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS00145 3d2bf26612ec4f8676f3ffe1cc54f30a 198 Gene3D G3DSA:3.40.1360.10 77 170 6.0E-41 T 29-03-2018 CXR48_RS00145 3d2bf26612ec4f8676f3ffe1cc54f30a 198 Pfam PF02132 RecR protein 40 78 1.5E-17 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 ProSitePatterns PS00012 Phosphopantetheine attachment site. 420 435 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3909 4023 2.0E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2453 2568 7.8E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 981 1095 3.1E-9 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00825 Beta-ketoacyl synthase 4739 5157 5.0E-152 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00825 Beta-ketoacyl synthase 2098 2503 2.0E-148 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00825 Beta-ketoacyl synthase 620 1039 6.7E-200 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00825 Beta-ketoacyl synthase 3534 3964 1.1E-203 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2096 2324 7.1E-67 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 619 852 6.3E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3532 3780 3.2E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4738 4981 3.9E-77 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:1.10.1200.10 3392 3483 2.3E-15 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:1.10.1200.10 356 468 1.6E-15 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 765 781 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.50.150 67 347 4.7E-19 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF53901 617 967 2.82E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF51735 1696 1923 3.06E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.47.10 2339 2501 6.9E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.47.10 867 1037 1.4E-53 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.47.10 3796 3962 8.2E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2237 2253 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF47336 394 463 6.54E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.50.720 4346 4593 2.4E-31 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3693 3709 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF51735 3136 3387 3.06E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 ProSitePatterns PS00012 Phosphopantetheine attachment site. 518 533 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF47336 4625 4749 7.98E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM01294 4631 4698 1.4E-7 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM01294 3410 3476 8.7E-6 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF53335 145 334 7.93E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF53901 2095 2438 9.98E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00823 Phosphopantetheine attachment site 3409 3480 2.4E-14 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00823 Phosphopantetheine attachment site 492 562 3.3E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00823 Phosphopantetheine attachment site 1975 2047 1.3E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00823 Phosphopantetheine attachment site 4630 4702 7.2E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00823 Phosphopantetheine attachment site 394 464 9.5E-15 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF47336 492 563 9.81E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.10.129.10 1212 1321 3.0E-4 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.10.129.10 2694 2817 4.9E-19 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2332 2449 1.1E-35 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4989 5106 5.6E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 860 977 2.1E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3788 3905 1.9E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF47336 1979 2048 3.53E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF47336 2080 2109 3.53E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF08242 Methyltransferase domain 173 277 1.3E-14 T 29-03-2018 IPR013217 Methyltransferase type 12 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00826 2692 2855 2.4E-17 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4894 4910 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.47.10 4997 5159 4.5E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF53901 3940 3959 1.25E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF53901 3530 3898 1.25E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF47336 3406 3481 1.7E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF51735 4349 4575 1.09E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1698 1884 8.7E-43 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3140 3327 2.5E-48 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4350 4545 1.5E-33 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF08659 KR domain 1699 1883 9.8E-49 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF08659 KR domain 4351 4544 6.8E-36 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF08659 KR domain 3140 3326 6.3E-53 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF14765 Polyketide synthase dehydratase 2692 2966 5.2E-57 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF14765 Polyketide synthase dehydratase 1209 1467 1.8E-25 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.47.10 2089 2336 1.8E-70 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.47.10 4733 4993 3.1E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.47.10 3524 3792 3.1E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.47.10 617 864 3.7E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF00550 Phosphopantetheine attachment site 3410 3476 8.2E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF00550 Phosphopantetheine attachment site 1979 2042 6.0E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF00550 Phosphopantetheine attachment site 4632 4698 2.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF00550 Phosphopantetheine attachment site 397 460 6.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Pfam PF00550 Phosphopantetheine attachment site 493 558 4.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 SUPERFAMILY SSF53901 4736 5103 2.81E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:1.10.1200.10 1972 2088 1.8E-13 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:1.10.1200.10 489 616 2.2E-15 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:1.10.1200.10 4623 4732 4.2E-17 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.50.720 1690 1955 1.3E-39 T 29-03-2018 CXR48_RS11345 0522f4c06200fbb3b16918e6b3b1be2e 5207 Gene3D G3DSA:3.40.50.720 3133 3391 5.8E-47 T 29-03-2018 CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 Gene3D G3DSA:3.40.50.2300 12 143 0.0016 T 29-03-2018 CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 6.3E-26 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 SUPERFAMILY SSF102114 127 363 2.88E-58 T 29-03-2018 CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 SMART SM00729 143 361 3.7E-61 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 Gene3D G3DSA:3.80.30.20 144 375 7.7E-51 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 Pfam PF04055 Radical SAM superfamily 149 319 3.4E-29 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 Pfam PF01938 TRAM domain 391 434 3.6E-6 T 29-03-2018 IPR002792 TRAM domain CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 431 9.3E-154 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 6 426 7.6E-107 T 29-03-2018 CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CXR48_RS12215 4870b34f4fd7324185f52a6a012c8132 451 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 4.9E-143 T 29-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 Gene3D G3DSA:3.40.720.10 303 511 1.7E-34 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 Gene3D G3DSA:3.40.1450.10 77 302 6.2E-99 T 29-03-2018 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 510 50.69 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 Pfam PF01676 Metalloenzyme superfamily 4 499 2.8E-79 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 PIRSF PIRSF001492 1 511 5.3E-209 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 509 3.8E-215 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 299 1.7E-86 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 SUPERFAMILY SSF64158 77 310 3.79E-93 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 SUPERFAMILY SSF53649 311 509 5.06E-76 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CXR48_RS16015 4fdba78f4f481d63c07f0f145e632266 511 SUPERFAMILY SSF53649 4 77 5.06E-76 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 Pfam PF00575 S1 RNA binding domain 133 195 1.4E-11 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 SUPERFAMILY SSF50249 132 198 1.27E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 Gene3D G3DSA:3.30.300.20 198 272 2.8E-35 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 Pfam PF13184 NusA-like KH domain 229 296 6.2E-29 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 SUPERFAMILY SSF54814 199 277 1.63E-30 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 Gene3D G3DSA:2.40.50.140 136 197 9.7E-16 T 29-03-2018 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 SUPERFAMILY SSF54814 278 341 2.29E-16 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 373 30.71 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 Pfam PF08529 NusA N-terminal domain 4 123 2.5E-46 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 SMART SM00316 133 199 9.2E-11 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 SMART SM00322 229 301 1.4E-5 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 SMART SM00322 302 360 10.0 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 Gene3D G3DSA:3.30.1480.10 1 129 1.1E-51 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 Gene3D G3DSA:3.30.300.20 273 341 1.4E-16 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 SUPERFAMILY SSF69705 1 126 4.45E-45 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CXR48_RS08280 c2ca253c8296a2d55de39ab2ded8b20b 373 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 8.2E-131 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CXR48_RS04375 a11d7a2f334d9cfe0617952c1f3ba4d6 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 1.1E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS04375 a11d7a2f334d9cfe0617952c1f3ba4d6 328 SUPERFAMILY SSF52540 5 254 2.72E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04375 a11d7a2f334d9cfe0617952c1f3ba4d6 328 Gene3D G3DSA:3.40.50.300 2 328 4.2E-79 T 29-03-2018 CXR48_RS04375 a11d7a2f334d9cfe0617952c1f3ba4d6 328 SMART SM00382 34 233 2.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04375 a11d7a2f334d9cfe0617952c1f3ba4d6 328 Pfam PF00005 ABC transporter 26 183 9.6E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS04375 a11d7a2f334d9cfe0617952c1f3ba4d6 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 320 5.4E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 SUPERFAMILY SSF55804 535 682 1.74E-14 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 SUPERFAMILY SSF46785 1 45 3.63E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Gene3D G3DSA:3.40.50.2300 410 499 5.7E-21 T 29-03-2018 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Pfam PF05043 Mga helix-turn-helix domain 86 158 9.1E-6 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Gene3D G3DSA:1.10.10.10 85 152 1.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Gene3D G3DSA:1.10.10.10 1 69 2.0E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 SUPERFAMILY SSF46785 87 152 3.04E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 SUPERFAMILY SSF52794 412 496 1.52E-12 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Gene3D G3DSA:1.10.1790.10 295 406 3.6E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Gene3D G3DSA:1.10.1790.10 178 294 6.2E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 SUPERFAMILY SSF63520 312 404 2.09E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 SUPERFAMILY SSF63520 197 293 2.88E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Pfam PF08279 HTH domain 6 63 1.2E-7 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Gene3D G3DSA:3.40.930.10 532 683 3.7E-12 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 414 490 3.1E-6 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Pfam PF00874 PRD domain 316 403 5.3E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Pfam PF00874 PRD domain 207 293 1.6E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS02145 eb072a1f7eb38f3e2c53ed9c33416d6b 694 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 555 682 7.6E-10 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 Gene3D G3DSA:2.30.24.10 8 66 2.1E-24 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 Gene3D G3DSA:1.10.1790.10 179 287 1.5E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 SUPERFAMILY SSF63520 186 283 1.57E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 SMART SM01061 12 70 1.4E-23 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 SUPERFAMILY SSF63520 66 177 2.09E-31 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 Gene3D G3DSA:1.10.1790.10 67 178 2.7E-27 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 Pfam PF03123 CAT RNA binding domain 13 68 4.3E-21 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 SUPERFAMILY SSF50151 12 64 3.01E-15 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 Pfam PF00874 PRD domain 192 282 1.8E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS06865 fd6c1d7931e617974462e07fd2d77afe 288 Pfam PF00874 PRD domain 87 174 3.4E-26 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS15970 306cc0a58eda1be538b0099fa0077fc1 225 Gene3D G3DSA:3.40.50.10320 1 224 2.8E-49 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CXR48_RS15970 306cc0a58eda1be538b0099fa0077fc1 225 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 130 4.7E-24 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CXR48_RS15970 306cc0a58eda1be538b0099fa0077fc1 225 SUPERFAMILY SSF102588 1 223 1.83E-46 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CXR48_RS14620 5b1b499b8a4f1d69511b7ef60afbef3d 166 Gene3D G3DSA:3.30.70.920 55 153 5.9E-26 T 29-03-2018 CXR48_RS14620 5b1b499b8a4f1d69511b7ef60afbef3d 166 Gene3D G3DSA:1.10.10.10 1 53 9.6E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14620 5b1b499b8a4f1d69511b7ef60afbef3d 166 SUPERFAMILY SSF46785 3 61 2.29E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14620 5b1b499b8a4f1d69511b7ef60afbef3d 166 SUPERFAMILY SSF54909 66 147 2.41E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS14620 5b1b499b8a4f1d69511b7ef60afbef3d 166 SMART SM00344 3 114 1.2E-5 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CXR48_RS14620 5b1b499b8a4f1d69511b7ef60afbef3d 166 Pfam PF01037 Lrp/AsnC ligand binding domain 72 144 2.0E-13 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CXR48_RS14620 5b1b499b8a4f1d69511b7ef60afbef3d 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 49 9.6E-6 T 29-03-2018 CXR48_RS18655 a7ec264d7a258d5a254cfc172a8bbfb9 320 Pfam PF01497 Periplasmic binding protein 72 287 4.4E-29 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CXR48_RS18655 a7ec264d7a258d5a254cfc172a8bbfb9 320 Gene3D G3DSA:3.40.50.1980 37 145 8.3E-19 T 29-03-2018 CXR48_RS18655 a7ec264d7a258d5a254cfc172a8bbfb9 320 Gene3D G3DSA:3.40.50.1980 146 320 2.5E-30 T 29-03-2018 CXR48_RS18655 a7ec264d7a258d5a254cfc172a8bbfb9 320 SUPERFAMILY SSF53807 39 304 5.49E-52 T 29-03-2018 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 Gene3D G3DSA:1.10.10.10 129 214 4.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.5E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.5E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.5E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 SMART SM00421 151 208 3.4E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 Gene3D G3DSA:3.40.50.2300 1 128 1.7E-19 T 29-03-2018 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 9.2E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 SMART SM00448 2 117 5.0E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 SUPERFAMILY SSF46894 147 210 1.5E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 Pfam PF00072 Response regulator receiver domain 4 117 4.9E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 SUPERFAMILY SSF52172 1 130 6.4E-20 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS14750 af48eb7a5c84b5358ebe7f928b37c211 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 Pfam PF02780 Transketolase, C-terminal domain 493 615 2.2E-33 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 SMART SM00861 316 481 6.2E-63 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 278 1.1E-115 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 624 44.713 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 Gene3D G3DSA:3.40.50.970 2 310 5.3E-74 T 29-03-2018 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 623 0.0 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 SUPERFAMILY SSF52922 489 621 2.22E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 SUPERFAMILY SSF52518 239 378 8.5E-71 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 SUPERFAMILY SSF52518 6 193 8.5E-71 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 Gene3D G3DSA:3.40.50.920 492 624 1.8E-35 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 Gene3D G3DSA:3.40.50.970 326 484 3.1E-43 T 29-03-2018 CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 6.7E-39 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS11655 8c0d279747d15857ec20abdcf1976fc6 633 SUPERFAMILY SSF52518 315 503 1.77E-54 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS08310 81bb8333409eb6fc365f58040ccbe427 309 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 178 3.0E-57 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CXR48_RS08310 81bb8333409eb6fc365f58040ccbe427 309 SUPERFAMILY SSF55120 1 221 4.08E-79 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS08310 81bb8333409eb6fc365f58040ccbe427 309 Gene3D G3DSA:3.30.2350.10 1 227 2.2E-83 T 29-03-2018 CXR48_RS08310 81bb8333409eb6fc365f58040ccbe427 309 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 303 19.097 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS08310 81bb8333409eb6fc365f58040ccbe427 309 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 2 217 9.6E-90 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS08310 81bb8333409eb6fc365f58040ccbe427 309 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 3.2E-13 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CXR48_RS15255 2a0b08421e87522be2bf21c5bc0b2726 278 Gene3D G3DSA:3.30.386.10 34 136 7.8E-42 T 29-03-2018 CXR48_RS15255 2a0b08421e87522be2bf21c5bc0b2726 278 Pfam PF01374 Glycosyl hydrolase family 46 49 265 8.4E-76 T 29-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 CXR48_RS15255 2a0b08421e87522be2bf21c5bc0b2726 278 ProSitePatterns PS60000 Chitosanases families 46 and 80 active sites signature. 48 88 - T 29-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 CXR48_RS15255 2a0b08421e87522be2bf21c5bc0b2726 278 Gene3D G3DSA:1.20.141.10 137 271 5.9E-46 T 29-03-2018 CXR48_RS15255 2a0b08421e87522be2bf21c5bc0b2726 278 PIRSF PIRSF036551 1 278 2.0E-98 T 29-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 CXR48_RS15255 2a0b08421e87522be2bf21c5bc0b2726 278 SUPERFAMILY SSF53955 19 277 2.17E-83 T 29-03-2018 IPR023346 Lysozyme-like domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 2364 2538 1.67E-34 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 4058 4300 1.01E-62 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00501 AMP-binding enzyme 1780 2174 1.6E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00501 AMP-binding enzyme 4338 4733 6.9E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00501 AMP-binding enzyme 3289 3693 2.2E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00501 AMP-binding enzyme 269 662 7.9E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:2.30.38.10 574 655 1.3E-23 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 1032 1285 3.89E-39 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF56801 1739 2294 4.32E-152 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 2830 3007 1.11E-42 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 2546 2793 3.78E-42 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2306 2321 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 1499 1767 4.78E-53 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF56801 4295 4852 6.15E-138 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 852 1026 2.0E-32 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF47336 4831 4905 7.33E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:1.10.1200.10 2286 2352 1.2E-17 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00550 Phosphopantetheine attachment site 3804 3867 4.6E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00550 Phosphopantetheine attachment site 772 834 2.7E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00550 Phosphopantetheine attachment site 2285 2346 4.3E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00550 Phosphopantetheine attachment site 4840 4904 1.3E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 3008 3252 8.34E-54 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:1.10.1200.10 776 832 1.1E-17 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:1.10.1200.10 3809 3869 1.2E-19 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:1.10.1200.10 4845 4909 1.9E-20 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SMART SM00823 Phosphopantetheine attachment site 2282 2350 9.7E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SMART SM00823 Phosphopantetheine attachment site 4839 4908 0.016 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SMART SM00823 Phosphopantetheine attachment site 770 838 0.0069 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SMART SM00823 Phosphopantetheine attachment site 3802 3871 9.6E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 5 254 2.22E-22 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.40.50.980 262 413 7.5E-48 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 3886 4070 7.11E-41 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:2.30.38.10 3604 3684 1.4E-22 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00668 Condensation domain 4921 5350 1.8E-124 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00668 Condensation domain 2359 2800 2.7E-106 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00668 Condensation domain 3886 4315 1.1E-130 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00668 Condensation domain 1316 1761 4.4E-123 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00668 Condensation domain 2824 3269 5.3E-123 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00668 Condensation domain 4 249 1.3E-21 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF00668 Condensation domain 851 1291 3.4E-102 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF47336 2274 2346 6.02E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 4920 5084 2.11E-41 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 5095 5341 1.67E-56 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF47336 3794 3867 3.14E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.559.10 4910 5101 2.1E-41 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF56801 3247 3815 6.41E-146 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.40.50.980 3434 3597 4.1E-28 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.40.50.980 414 573 4.8E-37 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.40.50.980 1926 2076 1.6E-28 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.40.50.980 4483 4635 3.7E-25 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1801 2198 1.1E-140 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 290 686 9.0E-138 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4359 4755 9.9E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3310 3717 8.6E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3826 3841 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4477 4488 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF52777 1321 1498 7.45E-41 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.300.30 2169 2285 4.4E-36 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.300.30 4728 4844 1.8E-31 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.300.30 657 775 1.2E-36 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.300.30 3689 3808 1.3E-33 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:2.30.38.10 2077 2166 1.2E-24 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:2.30.38.10 4636 4725 1.1E-21 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 794 809 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4863 4878 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF13193 AMP-binding enzyme C-terminal domain 2182 2255 3.2E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF13193 AMP-binding enzyme C-terminal domain 670 743 5.1E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF13193 AMP-binding enzyme C-terminal domain 4741 4812 2.6E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Pfam PF13193 AMP-binding enzyme C-terminal domain 3702 3775 9.5E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF47336 762 834 1.24E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 SUPERFAMILY SSF56801 230 782 1.44E-162 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1154 1305 1.5E-43 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2666 2814 3.5E-48 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.40.50.980 1772 1925 3.9E-46 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.40.50.980 3280 3433 2.4E-45 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.40.50.980 4330 4482 4.0E-42 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.559.10 3870 4072 2.2E-36 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.559.10 2816 3028 9.3E-39 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.559.10 833 1050 2.7E-29 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.559.10 1288 1521 5.0E-33 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 Gene3D G3DSA:3.30.559.10 2353 2564 1.3E-27 T 29-03-2018 CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1919 1930 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09100 5533789d067f0a254a96aa28db2dea8a 5362 ProSitePatterns PS00455 Putative AMP-binding domain signature. 408 419 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS03265 fd9ce1bfc25b363b2664d456c31a142d 162 SUPERFAMILY SSF52255 4 160 7.46E-69 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CXR48_RS03265 fd9ce1bfc25b363b2664d456c31a142d 162 Gene3D G3DSA:3.40.50.7700 1 162 1.1E-68 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CXR48_RS03265 fd9ce1bfc25b363b2664d456c31a142d 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 161 5.4E-68 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CXR48_RS03265 fd9ce1bfc25b363b2664d456c31a142d 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.29 T 29-03-2018 IPR033747 Class I PurE CXR48_RS03265 fd9ce1bfc25b363b2664d456c31a142d 162 SMART SM01001 3 154 7.9E-107 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CXR48_RS03265 fd9ce1bfc25b363b2664d456c31a142d 162 Pfam PF00731 AIR carboxylase 6 152 1.8E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CXR48_RS03265 fd9ce1bfc25b363b2664d456c31a142d 162 PIRSF PIRSF001338 1 162 1.1E-68 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CXR48_RS08820 652457ba4ced85c3649ba1a80b4375f7 32 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 6 28 4.4E-13 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS08820 652457ba4ced85c3649ba1a80b4375f7 32 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 5 29 8.4E-16 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS04425 c1cf78976ebe7e7ee72be04b4cbfd0b8 67 Gene3D G3DSA:1.10.260.40 1 67 8.9E-15 T 29-03-2018 CXR48_RS04425 c1cf78976ebe7e7ee72be04b4cbfd0b8 67 SMART SM00530 4 59 2.9E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS04425 c1cf78976ebe7e7ee72be04b4cbfd0b8 67 SUPERFAMILY SSF47413 2 63 1.77E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS04425 c1cf78976ebe7e7ee72be04b4cbfd0b8 67 Pfam PF01381 Helix-turn-helix 5 59 3.9E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 PIRSF PIRSF001529 1 425 1.8E-190 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 400 4.7E-39 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 2.7E-31 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 44.219 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 2.0E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 2.0E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 2.0E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 2.0E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 2.0E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 SUPERFAMILY SSF55681 117 422 1.44E-106 T 29-03-2018 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 SUPERFAMILY SSF46589 1 113 4.6E-31 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 Gene3D G3DSA:3.30.930.10 106 425 1.2E-101 T 29-03-2018 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 Gene3D G3DSA:1.10.287.40 2 105 7.9E-26 T 29-03-2018 CXR48_RS00090 9b1572006f25ea5829c423a0e0681afd 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 1.7E-188 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CXR48_RS17565 7936cdf03b8cf0969299571bd2876f26 173 Gene3D G3DSA:3.40.50.10490 1 171 1.4E-4 T 29-03-2018 CXR48_RS17565 7936cdf03b8cf0969299571bd2876f26 173 SUPERFAMILY SSF53697 1 164 2.22E-5 T 29-03-2018 CXR48_RS17565 7936cdf03b8cf0969299571bd2876f26 173 Pfam PF10740 Domain of unknown function (DUF2529) 1 169 1.8E-64 T 29-03-2018 IPR019676 Domain of unknown function (DUF2529) CXR48_RS12665 790098546c62dc95287a770012184f9c 206 Pfam PF13181 Tetratricopeptide repeat 160 193 8.5E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 Pfam PF13181 Tetratricopeptide repeat 1 20 0.14 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 Pfam PF13432 Tetratricopeptide repeat 96 159 4.9E-6 T 29-03-2018 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 SUPERFAMILY SSF81901 2 200 2.09E-34 T 29-03-2018 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 Gene3D G3DSA:1.25.40.10 50 78 1.7E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 Gene3D G3DSA:1.25.40.10 1 49 8.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 Gene3D G3DSA:1.25.40.10 140 171 1.4E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 Gene3D G3DSA:1.25.40.10 172 205 4.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 Pfam PF13414 TPR repeat 38 70 5.7E-7 T 29-03-2018 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 Gene3D G3DSA:1.25.40.10 79 139 5.4E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 SMART SM00028 160 193 0.015 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 SMART SM00028 126 159 0.058 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 SMART SM00028 24 57 0.082 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 SMART SM00028 58 91 2.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS12665 790098546c62dc95287a770012184f9c 206 SMART SM00028 92 125 0.0041 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 SUPERFAMILY SSF52029 183 374 1.18E-84 T 29-03-2018 IPR027409 GroEL-like apical domain CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 1.6E-259 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 Gene3D G3DSA:1.10.560.10 372 513 1.0E-27 T 29-03-2018 IPR027413 GroEL-like equatorial domain CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 Gene3D G3DSA:1.10.560.10 1 190 6.5E-36 T 29-03-2018 IPR027413 GroEL-like equatorial domain CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 SUPERFAMILY SSF48592 404 518 6.66E-81 T 29-03-2018 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 SUPERFAMILY SSF48592 5 133 6.66E-81 T 29-03-2018 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 Hamap MF_00600 60 kDa chaperonin [groL]. 1 543 42.66 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 9.4E-105 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 SUPERFAMILY SSF54849 136 204 3.89E-27 T 29-03-2018 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 Gene3D G3DSA:3.50.7.10 191 371 3.2E-98 T 29-03-2018 IPR027409 GroEL-like apical domain CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 82 109 3.0E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 26 52 3.0E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 266 289 3.0E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 348 373 3.0E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CXR48_RS03085 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 396 417 3.0E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CXR48_RS08495 1291a974978d237c8ab3c868c4061f27 181 Pfam PF10628 Outer spore coat protein E (CotE) 3 175 5.2E-68 T 29-03-2018 IPR018901 Spore coat protein CotE CXR48_RS15455 d2c0169aaae175875bb56fb0be6cb1be 291 Gene3D G3DSA:1.10.10.60 40 228 3.7E-11 T 29-03-2018 CXR48_RS15455 d2c0169aaae175875bb56fb0be6cb1be 291 SUPERFAMILY SSF46689 4 77 1.55E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS15455 d2c0169aaae175875bb56fb0be6cb1be 291 Gene3D G3DSA:1.10.10.60 2 39 4.1E-18 T 29-03-2018 CXR48_RS15455 d2c0169aaae175875bb56fb0be6cb1be 291 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CXR48_RS15455 d2c0169aaae175875bb56fb0be6cb1be 291 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 1.1E-19 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS15455 d2c0169aaae175875bb56fb0be6cb1be 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 9.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS15455 d2c0169aaae175875bb56fb0be6cb1be 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 9.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 Gene3D G3DSA:3.40.50.720 2 159 3.5E-30 T 29-03-2018 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 SUPERFAMILY SSF56327 173 440 8.64E-98 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 SUPERFAMILY SSF51735 4 170 3.26E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 3.9E-55 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 3.9E-55 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 3.9E-55 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 3.9E-55 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 3.9E-55 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 3.9E-55 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 3.9E-55 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 Gene3D G3DSA:3.90.110.10 160 436 5.6E-90 T 29-03-2018 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 6.1E-77 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS18260 ddf39ad018da1a2a26548f9636828e5c 442 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 412 6.6E-50 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Gene3D G3DSA:3.30.70.260 327 403 1.9E-21 T 29-03-2018 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 1.0E-156 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Gene3D G3DSA:3.40.1160.10 1 234 4.0E-70 T 29-03-2018 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 401 2.0E-142 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 SUPERFAMILY SSF53633 3 242 7.46E-73 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Gene3D G3DSA:3.30.70.260 235 326 6.2E-18 T 29-03-2018 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 SUPERFAMILY SSF55021 249 325 6.54E-15 T 29-03-2018 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 SUPERFAMILY SSF55021 330 403 6.18E-23 T 29-03-2018 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Pfam PF01842 ACT domain 275 326 5.1E-9 T 29-03-2018 IPR002912 ACT domain CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Pfam PF00696 Amino acid kinase family 3 229 2.6E-53 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Pfam PF13840 ACT domain 335 398 8.3E-16 T 29-03-2018 IPR027795 GATS-like ACT domain CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 PIRSF PIRSF000726 1 62 4.5E-21 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS13140 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 PIRSF PIRSF000726 53 409 2.0E-139 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 94 9.4E-17 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 507 650 6.7E-34 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 SUPERFAMILY SSF52794 2 103 6.28E-38 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 Gene3D G3DSA:3.40.50.2300 2 98 3.2E-40 T 29-03-2018 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 Gene3D G3DSA:3.40.930.10 502 652 6.9E-38 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 509 635 2.4E-38 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 SUPERFAMILY SSF55804 503 650 2.49E-38 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 112 458 6.0E-94 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 86 4.0E-31 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 Pfam PF02378 Phosphotransferase system, EIIC 128 403 3.3E-19 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS12455 5b7bad0f5acad5c104b10ce1f8f61d29 652 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 553 569 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Pfam PF00550 Phosphopantetheine attachment site 1495 1548 4.4E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Gene3D G3DSA:3.40.50.720 1182 1485 2.6E-38 T 29-03-2018 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 SUPERFAMILY SSF53901 33 415 7.64E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Gene3D G3DSA:1.10.1200.10 1486 1576 8.9E-12 T 29-03-2018 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Pfam PF14765 Polyketide synthase dehydratase 671 942 2.4E-45 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 300 417 2.6E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Gene3D G3DSA:3.40.47.10 28 304 4.8E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 420 530 2.7E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Gene3D G3DSA:3.40.47.10 307 468 3.7E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 SMART SM00825 Beta-ketoacyl synthase 38 470 1.0E-158 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 SMART SM00823 Phosphopantetheine attachment site 1482 1552 0.006 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Pfam PF08659 KR domain 1186 1381 1.0E-52 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 206 222 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1186 1382 1.4E-41 T 29-03-2018 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1507 1522 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 SMART SM00826 671 830 0.0012 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Gene3D G3DSA:3.10.129.10 673 791 2.0E-9 T 29-03-2018 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 SUPERFAMILY SSF51735 951 1167 2.56E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 SUPERFAMILY SSF51735 1184 1430 4.74E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 SUPERFAMILY SSF47336 1479 1549 3.01E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 SMART SM01294 1484 1548 8.3E-4 T 29-03-2018 CXR48_RS01210 77c4b0eee12ac46b54b46cecc53fe651 1596 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 292 4.8E-57 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 ProSitePatterns PS00123 Alkaline phosphatase active site. 103 111 - T 29-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 Pfam PF00245 Alkaline phosphatase 47 456 1.4E-130 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 Gene3D G3DSA:3.40.720.10 25 459 3.8E-125 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 PRINTS PR00113 Alkaline phosphatase signature 103 118 7.1E-43 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 PRINTS PR00113 Alkaline phosphatase signature 256 285 7.1E-43 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 PRINTS PR00113 Alkaline phosphatase signature 140 160 7.1E-43 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 PRINTS PR00113 Alkaline phosphatase signature 47 67 7.1E-43 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 PRINTS PR00113 Alkaline phosphatase signature 190 200 7.1E-43 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 SUPERFAMILY SSF53649 34 457 6.87E-123 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CXR48_RS04690 028b89df3737e82623d4d91152bfde59 459 SMART SM00098 48 458 5.8E-190 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CXR48_RS11500 bfe5c183dadb61271d9f38d592c12756 145 Pfam PF06491 Disulphide isomerase 8 142 3.8E-63 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CXR48_RS11500 bfe5c183dadb61271d9f38d592c12756 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 142 6.5E-64 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 SUPERFAMILY SSF81665 644 693 3.4E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 SUPERFAMILY SSF81665 143 202 3.4E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 SUPERFAMILY SSF81665 299 394 3.4E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 174 674 3.5E-72 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 548 3.9E-22 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 594 613 3.9E-22 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 618 630 3.9E-22 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 400 414 3.9E-22 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 248 262 3.9E-22 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 Gene3D G3DSA:3.40.1110.10 415 514 7.4E-26 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 Pfam PF00122 E1-E2 ATPase 199 379 5.9E-45 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 149 699 1.6E-155 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00941 Cadmium-transporting ATPase signature 19 40 2.8E-14 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00941 Cadmium-transporting ATPase signature 264 280 2.8E-14 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00941 Cadmium-transporting ATPase signature 183 203 2.8E-14 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00941 Cadmium-transporting ATPase signature 283 297 2.8E-14 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 PRINTS PR00941 Cadmium-transporting ATPase signature 8 17 2.8E-14 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 Pfam PF00702 haloacid dehalogenase-like hydrolase 399 608 1.9E-34 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 Gene3D G3DSA:3.40.50.1000 515 667 5.1E-33 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 Gene3D G3DSA:3.30.70.100 3 83 6.6E-12 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 SUPERFAMILY SSF56784 456 695 2.09E-58 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 SUPERFAMILY SSF56784 400 418 2.09E-58 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 150 697 2.2E-169 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 Gene3D G3DSA:1.20.1110.10 91 414 6.5E-29 T 29-03-2018 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 SUPERFAMILY SSF81653 201 298 3.27E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 Pfam PF00403 Heavy-metal-associated domain 10 65 6.4E-8 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 SUPERFAMILY SSF55008 7 77 2.09E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CXR48_RS15730 97365e1217e62f3de3139a3c3ccf126c 703 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 402 408 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CXR48_RS09985 3c5feeec6b082cc33b73d354791211ef 177 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 164 36.801 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CXR48_RS09985 3c5feeec6b082cc33b73d354791211ef 177 Gene3D G3DSA:3.30.1060.10 1 172 1.8E-66 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CXR48_RS09985 3c5feeec6b082cc33b73d354791211ef 177 SUPERFAMILY SSF55068 3 168 7.59E-72 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CXR48_RS09985 3c5feeec6b082cc33b73d354791211ef 177 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 157 2.1E-69 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CXR48_RS09985 3c5feeec6b082cc33b73d354791211ef 177 Pfam PF01625 Peptide methionine sulfoxide reductase 8 157 2.4E-61 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CXR48_RS09345 b27298c5c68300353fb047986365fd80 282 Gene3D G3DSA:3.40.50.720 5 169 1.2E-22 T 29-03-2018 CXR48_RS09345 b27298c5c68300353fb047986365fd80 282 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 8 272 24.23 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CXR48_RS09345 b27298c5c68300353fb047986365fd80 282 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 9 105 5.6E-19 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CXR48_RS09345 b27298c5c68300353fb047986365fd80 282 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 168 271 8.2E-33 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CXR48_RS09345 b27298c5c68300353fb047986365fd80 282 SUPERFAMILY SSF48179 167 275 2.21E-32 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS09345 b27298c5c68300353fb047986365fd80 282 PIRSF PIRSF000193 7 275 2.7E-72 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CXR48_RS09345 b27298c5c68300353fb047986365fd80 282 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 10 271 5.7E-82 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CXR48_RS09345 b27298c5c68300353fb047986365fd80 282 Gene3D G3DSA:1.10.3730.10 170 277 1.2E-36 T 29-03-2018 CXR48_RS09345 b27298c5c68300353fb047986365fd80 282 SUPERFAMILY SSF51735 8 166 1.18E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS09285 f97d7a2f338933f0be1e811dc5dbaaeb 181 SUPERFAMILY SSF56349 6 179 2.53E-39 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CXR48_RS09285 f97d7a2f338933f0be1e811dc5dbaaeb 181 Gene3D G3DSA:1.10.443.10 9 176 5.4E-32 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CXR48_RS09285 f97d7a2f338933f0be1e811dc5dbaaeb 181 Pfam PF00589 Phage integrase family 21 164 2.2E-24 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CXR48_RS08120 2d69a815d6a4e234c83d82636ea7b37c 258 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CXR48_RS08120 2d69a815d6a4e234c83d82636ea7b37c 258 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 237 3.3E-57 T 29-03-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 CXR48_RS08120 2d69a815d6a4e234c83d82636ea7b37c 258 SUPERFAMILY SSF117143 86 218 2.48E-35 T 29-03-2018 CXR48_RS08120 2d69a815d6a4e234c83d82636ea7b37c 258 Pfam PF00460 Flagella basal body rod protein 5 35 3.9E-13 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CXR48_RS08120 2d69a815d6a4e234c83d82636ea7b37c 258 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 144 239 3.4E-31 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CXR48_RS08120 2d69a815d6a4e234c83d82636ea7b37c 258 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 128 4.8E-44 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CXR48_RS08120 2d69a815d6a4e234c83d82636ea7b37c 258 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 177 256 1.8E-25 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 Gene3D G3DSA:3.30.1360.120 2 129 3.4E-35 T 29-03-2018 CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 Gene3D G3DSA:4.10.1250.10 238 278 8.8E-14 T 29-03-2018 CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 SUPERFAMILY SSF101790 273 362 3.76E-27 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 266 356 1.2E-27 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 362 1.5E-160 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 PIRSF PIRSF006487 1 366 8.5E-107 T 29-03-2018 CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 SUPERFAMILY SSF103025 2 281 4.49E-101 T 29-03-2018 CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 362 48.728 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 Gene3D G3DSA:3.30.1360.120 130 235 1.3E-31 T 29-03-2018 CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 Gene3D G3DSA:2.40.30.110 281 366 3.5E-27 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CXR48_RS11800 c4132695360fe7b0a4183f74b640a2cc 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 258 9.5E-97 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CXR48_RS06460 42b223f19b76abf57ed32e3a0d3a139f 299 Gene3D G3DSA:3.90.1720.10 163 299 5.0E-31 T 29-03-2018 CXR48_RS06460 42b223f19b76abf57ed32e3a0d3a139f 299 Pfam PF00877 NlpC/P60 family 185 292 5.2E-24 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CXR48_RS06460 42b223f19b76abf57ed32e3a0d3a139f 299 SUPERFAMILY SSF54001 169 294 1.91E-33 T 29-03-2018 CXR48_RS06460 42b223f19b76abf57ed32e3a0d3a139f 299 Gene3D G3DSA:2.30.30.40 42 107 2.4E-7 T 29-03-2018 CXR48_RS14660 049b061f51bcd3935d1625db43f89c67 624 SUPERFAMILY SSF56601 299 624 1.47E-94 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS14660 049b061f51bcd3935d1625db43f89c67 624 SUPERFAMILY SSF56601 221 243 1.47E-94 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS14660 049b061f51bcd3935d1625db43f89c67 624 SUPERFAMILY SSF53955 54 265 9.56E-71 T 29-03-2018 IPR023346 Lysozyme-like domain CXR48_RS14660 049b061f51bcd3935d1625db43f89c67 624 Pfam PF00912 Transglycosylase 63 238 1.2E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CXR48_RS14660 049b061f51bcd3935d1625db43f89c67 624 Gene3D G3DSA:3.40.710.10 258 624 1.6E-85 T 29-03-2018 CXR48_RS14660 049b061f51bcd3935d1625db43f89c67 624 Gene3D G3DSA:1.10.3810.10 56 257 3.2E-72 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CXR48_RS14660 049b061f51bcd3935d1625db43f89c67 624 Pfam PF00905 Penicillin binding protein transpeptidase domain 350 590 5.7E-27 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SMART SM00823 Phosphopantetheine attachment site 1750 1821 3.9E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SMART SM00823 Phosphopantetheine attachment site 538 608 9.1E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF08659 KR domain 1466 1666 1.5E-41 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF08659 KR domain 274 453 1.1E-53 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SUPERFAMILY SSF51735 272 492 2.45E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF00550 Phosphopantetheine attachment site 1751 1813 5.8E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF00550 Phosphopantetheine attachment site 540 603 3.5E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SUPERFAMILY SSF51735 1463 1670 5.15E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1020 1128 1.0E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2235 2283 5.2E-7 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SUPERFAMILY SSF51735 1253 1443 3.54E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Gene3D G3DSA:3.40.50.720 270 545 5.3E-46 T 29-03-2018 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Gene3D G3DSA:3.40.47.10 2123 2286 3.4E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Gene3D G3DSA:1.10.1200.10 1723 1824 2.5E-13 T 29-03-2018 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2020 2036 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Gene3D G3DSA:1.10.1200.10 546 642 3.1E-12 T 29-03-2018 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1864 2107 2.5E-82 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 647 892 1.1E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Gene3D G3DSA:3.40.47.10 907 1068 6.1E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 274 455 2.0E-48 T 29-03-2018 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1465 1667 4.5E-31 T 29-03-2018 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SMART SM00825 Beta-ketoacyl synthase 1866 2285 2.7E-170 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SMART SM00825 Beta-ketoacyl synthase 649 1070 3.8E-206 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1776 1791 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Gene3D G3DSA:3.40.47.10 643 904 7.5E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Gene3D G3DSA:3.40.47.10 1856 2119 2.6E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SMART SM01294 1751 1817 1.8E-5 T 29-03-2018 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SUPERFAMILY SSF53901 1862 2228 1.38E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SUPERFAMILY SSF53901 2260 2280 1.38E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SUPERFAMILY SSF53901 644 1009 1.34E-94 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SUPERFAMILY SSF53901 1045 1066 1.34E-94 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 900 1016 1.3E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2115 2232 4.8E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SUPERFAMILY SSF47336 536 661 1.31E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 Gene3D G3DSA:3.40.50.720 1463 1702 1.2E-33 T 29-03-2018 CXR48_RS07240 e941a0fe685cf811cca670928e45114c 2332 SUPERFAMILY SSF47336 1747 1830 1.44E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 SUPERFAMILY SSF100950 72 233 3.03E-32 T 29-03-2018 CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 23 37 1.0E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 37 55 1.0E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 SMART SM01134 71 232 6.3E-62 T 29-03-2018 CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 SUPERFAMILY SSF46785 5 58 1.59E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 Gene3D G3DSA:1.10.10.10 2 57 1.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 SMART SM00420 5 57 9.9E-23 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 Pfam PF08220 DeoR-like helix-turn-helix domain 5 60 2.3E-21 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 Gene3D G3DSA:3.40.50.1360 63 235 6.1E-36 T 29-03-2018 CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CXR48_RS18735 74aeb2b39a8caaf9ae41b9049a6d206a 251 Pfam PF00455 DeoR C terminal sensor domain 73 230 4.8E-51 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CXR48_RS11140 6861ec3a15664e83a4c11c5facd48019 272 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 74 115 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CXR48_RS11140 6861ec3a15664e83a4c11c5facd48019 272 SUPERFAMILY SSF53167 3 269 8.25E-100 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CXR48_RS11140 6861ec3a15664e83a4c11c5facd48019 272 Pfam PF01048 Phosphorylase superfamily 21 268 1.2E-57 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CXR48_RS11140 6861ec3a15664e83a4c11c5facd48019 272 Gene3D G3DSA:3.40.50.1580 1 270 1.2E-75 T 29-03-2018 CXR48_RS11140 6861ec3a15664e83a4c11c5facd48019 272 PIRSF PIRSF000477 1 270 3.6E-124 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CXR48_RS11140 6861ec3a15664e83a4c11c5facd48019 272 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 21 268 3.6E-124 T 29-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CXR48_RS11140 6861ec3a15664e83a4c11c5facd48019 272 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 21 267 1.9E-110 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CXR48_RS14765 c2a92ca50dce18989cc61ad41605f7dd 303 Pfam PF00348 Polyprenyl synthetase 47 223 9.9E-15 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CXR48_RS14765 c2a92ca50dce18989cc61ad41605f7dd 303 SUPERFAMILY SSF48576 44 277 2.64E-33 T 29-03-2018 IPR008949 Isoprenoid synthase domain CXR48_RS14765 c2a92ca50dce18989cc61ad41605f7dd 303 Gene3D G3DSA:1.10.600.10 4 300 8.9E-30 T 29-03-2018 IPR008949 Isoprenoid synthase domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SUPERFAMILY SSF56801 1161 1715 7.33E-138 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 517 4.3E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:3.30.300.30 1594 1707 1.5E-27 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SUPERFAMILY SSF53901 39 408 2.73E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:2.30.38.10 1496 1591 9.5E-25 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SUPERFAMILY SSF47336 1695 1764 6.54E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:3.30.559.10 1768 1952 1.3E-18 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:3.40.50.980 1339 1495 5.5E-32 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Pfam PF00668 Condensation domain 1780 2204 8.5E-69 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Pfam PF00668 Condensation domain 749 1179 5.9E-112 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 42 285 7.4E-68 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:1.10.1200.10 1708 1767 8.5E-15 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 ProSitePatterns PS00012 Phosphopantetheine attachment site. 685 700 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1220 1623 7.0E-130 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:1.10.1200.10 650 737 2.7E-12 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SMART SM00825 Beta-ketoacyl synthase 43 463 1.4E-168 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 6.0E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 200 216 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:3.40.47.10 300 461 6.4E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SUPERFAMILY SSF47336 660 727 6.02E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SMART SM01294 669 726 2.3E-4 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2084 2201 1.2E-24 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Pfam PF13193 AMP-binding enzyme C-terminal domain 1610 1675 2.0E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Pfam PF00501 AMP-binding enzyme 1199 1599 2.0E-96 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SUPERFAMILY SSF52777 752 914 2.56E-37 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SMART SM00823 Phosphopantetheine attachment site 661 730 0.0035 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SUPERFAMILY SSF52777 1967 2204 7.23E-24 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SUPERFAMILY SSF52777 1786 1956 3.0E-30 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:3.40.47.10 33 296 8.6E-68 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:3.40.50.980 1192 1338 2.2E-41 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 SUPERFAMILY SSF52777 920 1162 3.45E-54 T 29-03-2018 CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Pfam PF00550 Phosphopantetheine attachment site 1705 1764 2.3E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Pfam PF00550 Phosphopantetheine attachment site 666 726 3.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1337 1348 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01220 2a68bf6442a6f1e9c01937bb682d8eae 2206 Gene3D G3DSA:3.30.559.10 738 935 3.6E-31 T 29-03-2018 CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 6 296 5.1E-101 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 89 4.4E-23 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 296 1.2E-119 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 296 63.892 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 Gene3D G3DSA:1.10.150.130 1 110 5.0E-20 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 Pfam PF00589 Phage integrase family 111 282 4.9E-56 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 SUPERFAMILY SSF47823 4 99 1.47E-18 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 296 56.35 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 SUPERFAMILY SSF56349 106 294 5.3E-60 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CXR48_RS11150 0a8393fd9f905d98f6d7ce7aebd606f7 296 Gene3D G3DSA:1.10.443.10 111 290 1.4E-52 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CXR48_RS16885 0fcafd842ebaec4314a5539be8580bde 285 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 277 1.2E-63 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS16885 0fcafd842ebaec4314a5539be8580bde 285 Gene3D G3DSA:3.40.50.1000 1 285 7.0E-41 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS16885 0fcafd842ebaec4314a5539be8580bde 285 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 277 7.9E-57 T 29-03-2018 IPR000150 Cof family GO:0016787 CXR48_RS16885 0fcafd842ebaec4314a5539be8580bde 285 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 250 1.1E-29 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CXR48_RS16885 0fcafd842ebaec4314a5539be8580bde 285 SUPERFAMILY SSF56784 2 281 4.07E-67 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS16885 0fcafd842ebaec4314a5539be8580bde 285 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 29-03-2018 CXR48_RS12780 3affbc39e3aa07f79e94a752ac79c433 342 Gene3D G3DSA:3.40.1780.10 172 342 2.8E-68 T 29-03-2018 CXR48_RS12780 3affbc39e3aa07f79e94a752ac79c433 342 Gene3D G3DSA:3.40.1780.10 1 144 3.3E-40 T 29-03-2018 CXR48_RS12780 3affbc39e3aa07f79e94a752ac79c433 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.546 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CXR48_RS12780 3affbc39e3aa07f79e94a752ac79c433 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 3.0E-140 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CXR48_RS12780 3affbc39e3aa07f79e94a752ac79c433 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 342 5.5E-156 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CXR48_RS12780 3affbc39e3aa07f79e94a752ac79c433 342 SUPERFAMILY SSF111337 1 342 9.42E-139 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CXR48_RS00440 33878885b4a7bff32ae0a09633ee9f77 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 293 1.5E-71 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS00440 33878885b4a7bff32ae0a09633ee9f77 308 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 305 1.8E-147 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CXR48_RS00440 33878885b4a7bff32ae0a09633ee9f77 308 Gene3D G3DSA:3.40.50.1100 39 142 7.8E-42 T 29-03-2018 CXR48_RS00440 33878885b4a7bff32ae0a09633ee9f77 308 SUPERFAMILY SSF53686 3 306 8.25E-106 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS00440 33878885b4a7bff32ae0a09633ee9f77 308 Gene3D G3DSA:3.40.50.1100 143 307 2.0E-56 T 29-03-2018 CXR48_RS00440 33878885b4a7bff32ae0a09633ee9f77 308 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CXR48_RS00440 33878885b4a7bff32ae0a09633ee9f77 308 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 305 8.0E-138 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 SUPERFAMILY SSF47336 295 373 4.58E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 Pfam PF08659 KR domain 712 896 2.4E-48 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 SMART SM00823 Phosphopantetheine attachment site 299 370 2.9E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 SMART SM00823 Phosphopantetheine attachment site 392 463 5.6E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 SUPERFAMILY SSF53474 1042 1277 2.7E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 Gene3D G3DSA:3.40.50.720 700 942 1.0E-38 T 29-03-2018 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 SUPERFAMILY SSF51735 488 681 4.72E-7 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 SUPERFAMILY SSF47336 388 476 1.15E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 Pfam PF00561 alpha/beta hydrolase fold 1059 1164 3.5E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 Gene3D G3DSA:1.10.1200.10 275 375 3.4E-12 T 29-03-2018 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 Gene3D G3DSA:1.10.1200.10 376 471 7.0E-16 T 29-03-2018 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 712 897 2.4E-36 T 29-03-2018 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 SUPERFAMILY SSF51735 708 913 9.59E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 Pfam PF14765 Polyketide synthase dehydratase 14 274 1.9E-18 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 Pfam PF00550 Phosphopantetheine attachment site 394 459 6.7E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 Pfam PF00550 Phosphopantetheine attachment site 302 366 2.0E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 SMART SM01294 389 459 3.8E-4 T 29-03-2018 CXR48_RS07255 4aeb5145ce2705744650df547e6c6405 1284 Gene3D G3DSA:3.40.50.1820 1026 1279 3.5E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14830 48e81e3ae0c498c5752dbd9bb42ff12e 157 TIGRFAM TIGR03927 T7SS_EssA_Firm: type VII secretion protein EssA 6 150 1.5E-47 T 29-03-2018 IPR018920 ESAT-6 secretion machinery protein EssA/YueC CXR48_RS14830 48e81e3ae0c498c5752dbd9bb42ff12e 157 ProDom PD090911 YUEC MEMBRANE TRANSMEMBRANE 24 153 7.0E-41 T 29-03-2018 IPR020212 ESX secretion system protein YueC CXR48_RS14830 48e81e3ae0c498c5752dbd9bb42ff12e 157 Pfam PF17355 Family of unknown function (DUF5383) 29 152 7.1E-37 T 29-03-2018 IPR020212 ESX secretion system protein YueC CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF52777 13 190 2.78E-45 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF52777 2087 2260 6.0E-38 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:3.40.50.980 1651 1808 8.8E-32 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:3.40.50.980 614 781 9.5E-34 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:1.10.1200.10 2008 2072 1.5E-20 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:3.30.559.10 1042 1241 1.3E-42 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:3.30.559.10 5 213 6.2E-35 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:3.30.559.10 2073 2288 1.8E-29 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF52777 191 435 4.78E-45 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF47336 968 1041 3.89E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1645 1656 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SMART SM00823 Phosphopantetheine attachment site 2004 2072 1.5E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SMART SM00823 Phosphopantetheine attachment site 976 1045 0.002 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:1.10.1200.10 981 1041 2.1E-21 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Pfam PF00501 AMP-binding enzyme 469 873 1.2E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Pfam PF00501 AMP-binding enzyme 1506 1898 2.8E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF47336 1996 2069 8.9E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF52777 1055 1239 4.34E-43 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF52777 2269 2518 1.67E-35 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:3.30.300.30 868 980 2.6E-36 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:3.30.300.30 1893 2007 3.9E-39 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF56801 428 988 1.57E-153 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:2.30.38.10 1809 1888 1.2E-24 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:2.30.38.10 783 863 1.4E-24 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Pfam PF00668 Condensation domain 1058 1483 1.5E-136 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Pfam PF00668 Condensation domain 2081 2534 9.3E-102 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Pfam PF00668 Condensation domain 8 448 2.0E-124 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF56801 1465 2016 1.05E-155 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Pfam PF13193 AMP-binding enzyme C-terminal domain 881 950 1.3E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Pfam PF13193 AMP-binding enzyme C-terminal domain 1906 1979 1.7E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:3.40.50.980 1497 1650 1.4E-41 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Gene3D G3DSA:3.40.50.980 460 613 2.6E-46 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2389 2542 4.9E-49 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 490 897 9.3E-131 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1527 1922 4.6E-130 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 SUPERFAMILY SSF52777 1226 1469 2.11E-63 T 29-03-2018 CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2028 2043 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 608 619 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Pfam PF00550 Phosphopantetheine attachment site 2006 2065 8.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09240 8733d5af2f963bec39f9e2e553b4af28 2549 Pfam PF00550 Phosphopantetheine attachment site 978 1039 2.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS02875 ed9b81f7c9caba6191a688a1764aef43 260 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 134 148 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CXR48_RS02875 ed9b81f7c9caba6191a688a1764aef43 260 Pfam PF08241 Methyltransferase domain 48 143 1.2E-22 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CXR48_RS02875 ed9b81f7c9caba6191a688a1764aef43 260 SUPERFAMILY SSF53335 11 242 1.51E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS02875 ed9b81f7c9caba6191a688a1764aef43 260 Gene3D G3DSA:3.40.50.150 29 239 7.1E-44 T 29-03-2018 CXR48_RS13325 a0d555af34b8605ea08d5d1dce47cf91 88 Pfam PF06961 Protein of unknown function (DUF1294) 11 65 4.2E-22 T 29-03-2018 IPR010718 Protein of unknown function DUF1294 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 425 1.9E-152 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 429 29.045 T 29-03-2018 IPR026593 Protein translocase subunit SecY CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 Pfam PF00344 SecY translocase 68 413 1.4E-111 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 SUPERFAMILY SSF103491 2 420 2.48E-126 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 Gene3D G3DSA:1.10.3370.10 1 431 4.3E-151 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 3.8E-101 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 3.8E-101 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 3.8E-101 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 3.8E-101 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 3.8E-101 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 3.8E-101 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 3.8E-101 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 3.8E-101 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 3.8E-101 T 29-03-2018 CXR48_RS00835 20ef1c5bb09d5a6879b0fee977d44d79 431 PIRSF PIRSF004557 1 431 7.6E-124 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CXR48_RS05380 4d0d5ac847468dffc6769141358cee44 343 Gene3D G3DSA:3.30.360.10 137 334 1.1E-43 T 29-03-2018 CXR48_RS05380 4d0d5ac847468dffc6769141358cee44 343 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 244 2.8E-13 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CXR48_RS05380 4d0d5ac847468dffc6769141358cee44 343 Gene3D G3DSA:3.40.50.720 1 136 2.0E-41 T 29-03-2018 CXR48_RS05380 4d0d5ac847468dffc6769141358cee44 343 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 125 8.1E-30 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CXR48_RS05380 4d0d5ac847468dffc6769141358cee44 343 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 5 332 3.3E-107 T 29-03-2018 IPR030827 Inositol 2-dehydrogenase CXR48_RS05380 4d0d5ac847468dffc6769141358cee44 343 SUPERFAMILY SSF55347 130 302 2.45E-30 T 29-03-2018 CXR48_RS05380 4d0d5ac847468dffc6769141358cee44 343 SUPERFAMILY SSF51735 3 153 8.47E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS02375 a6bf94605dbdaa0bae033c6dce1d3f63 105 Gene3D G3DSA:3.40.30.10 2 67 7.7E-18 T 29-03-2018 CXR48_RS02375 a6bf94605dbdaa0bae033c6dce1d3f63 105 SUPERFAMILY SSF52833 2 105 3.89E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS02375 a6bf94605dbdaa0bae033c6dce1d3f63 105 Pfam PF00085 Thioredoxin 5 103 2.3E-19 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CXR48_RS02375 a6bf94605dbdaa0bae033c6dce1d3f63 105 PIRSF PIRSF000077 1 105 3.8E-20 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CXR48_RS02375 a6bf94605dbdaa0bae033c6dce1d3f63 105 Gene3D G3DSA:3.40.30.10 68 104 2.4E-4 T 29-03-2018 CXR48_RS10640 c1e0731eb33865a006c1f3325ae512b4 377 Pfam PF13439 Glycosyltransferase Family 4 14 178 3.9E-27 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CXR48_RS10640 c1e0731eb33865a006c1f3325ae512b4 377 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 4 373 1.6E-174 T 29-03-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 CXR48_RS10640 c1e0731eb33865a006c1f3325ae512b4 377 SUPERFAMILY SSF53756 9 374 1.61E-86 T 29-03-2018 CXR48_RS10640 c1e0731eb33865a006c1f3325ae512b4 377 Gene3D G3DSA:3.40.50.2000 189 357 9.4E-41 T 29-03-2018 CXR48_RS10640 c1e0731eb33865a006c1f3325ae512b4 377 Gene3D G3DSA:3.40.50.2000 1 188 2.6E-20 T 29-03-2018 CXR48_RS10640 c1e0731eb33865a006c1f3325ae512b4 377 Pfam PF00534 Glycosyl transferases group 1 187 351 5.2E-42 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CXR48_RS05075 20cff37de9a00728fa266f38344c0452 325 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 3 323 2.8E-102 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CXR48_RS05075 20cff37de9a00728fa266f38344c0452 325 Gene3D G3DSA:3.40.47.10 163 323 1.2E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05075 20cff37de9a00728fa266f38344c0452 325 SUPERFAMILY SSF53901 2 323 9.89E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05075 20cff37de9a00728fa266f38344c0452 325 Gene3D G3DSA:3.40.47.10 3 162 1.5E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05075 20cff37de9a00728fa266f38344c0452 325 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 234 323 5.0E-32 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CXR48_RS05075 20cff37de9a00728fa266f38344c0452 325 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 323 61.82 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CXR48_RS05075 20cff37de9a00728fa266f38344c0452 325 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 184 2.0E-26 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CXR48_RS09705 00f1ee7674a7d6807d95d81c87e591e5 241 SUPERFAMILY SSF64288 76 230 4.71E-39 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS09705 00f1ee7674a7d6807d95d81c87e591e5 241 SMART SM00345 7 66 1.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS09705 00f1ee7674a7d6807d95d81c87e591e5 241 Pfam PF07702 UTRA domain 90 223 2.5E-26 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS09705 00f1ee7674a7d6807d95d81c87e591e5 241 Gene3D G3DSA:1.10.10.10 2 72 1.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09705 00f1ee7674a7d6807d95d81c87e591e5 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 1.3E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS09705 00f1ee7674a7d6807d95d81c87e591e5 241 SMART SM00866 87 226 6.0E-28 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS09705 00f1ee7674a7d6807d95d81c87e591e5 241 SUPERFAMILY SSF46785 5 75 5.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09705 00f1ee7674a7d6807d95d81c87e591e5 241 Gene3D G3DSA:3.40.1410.10 73 236 1.1E-31 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 SUPERFAMILY SSF47005 117 160 2.09E-9 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 Gene3D G3DSA:3.90.1170.30 1 47 2.4E-15 T 29-03-2018 CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 Gene3D G3DSA:3.30.559.10 173 413 5.0E-87 T 29-03-2018 CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 Gene3D G3DSA:4.10.320.10 124 172 1.2E-18 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 Gene3D G3DSA:2.40.50.100 48 123 7.3E-5 T 29-03-2018 CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 Pfam PF00364 Biotin-requiring enzyme 3 75 2.0E-23 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 SUPERFAMILY SSF51230 2 94 2.09E-26 T 29-03-2018 IPR011053 Single hybrid motif CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 185 413 1.1E-77 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 414 7.4E-176 T 29-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 Pfam PF02817 e3 binding domain 123 157 9.5E-13 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS09575 2a734a5ffc0a5499274a219281f91083 415 SUPERFAMILY SSF52777 184 413 2.31E-85 T 29-03-2018 CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 SUPERFAMILY SSF55874 309 449 2.88E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 304 2.3E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 SMART SM00304 187 239 4.4E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 SUPERFAMILY SSF158472 188 236 2.09E-8 T 29-03-2018 CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 SMART SM00387 350 451 3.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 443 2.0E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 Gene3D G3DSA:3.30.565.10 288 451 8.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 Pfam PF00672 HAMP domain 188 235 2.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 Gene3D G3DSA:1.10.287.130 230 287 2.7E-12 T 29-03-2018 CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 SMART SM00388 240 306 1.1E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS15445 d6d05f19c3742962425604d754337afa 451 SUPERFAMILY SSF47384 224 304 3.73E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS18415 c2c37508c2802e9a5cb28f408735c261 278 PIRSF PIRSF006483 1 278 1.1E-83 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS18415 c2c37508c2802e9a5cb28f408735c261 278 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 1.8E-21 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CXR48_RS18415 c2c37508c2802e9a5cb28f408735c261 278 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 210 6.6E-64 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS00970 684e2b318d18e6fce9905e22cde7f919 404 Gene3D G3DSA:1.20.1250.20 186 390 1.3E-23 T 29-03-2018 CXR48_RS00970 684e2b318d18e6fce9905e22cde7f919 404 Pfam PF07690 Major Facilitator Superfamily 12 173 1.7E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS00970 684e2b318d18e6fce9905e22cde7f919 404 Pfam PF07690 Major Facilitator Superfamily 215 388 1.6E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS00970 684e2b318d18e6fce9905e22cde7f919 404 SUPERFAMILY SSF103473 4 385 3.01E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS00970 684e2b318d18e6fce9905e22cde7f919 404 Gene3D G3DSA:1.20.1250.20 1 175 5.0E-21 T 29-03-2018 CXR48_RS18175 716cfc07405264935bb8402314744156 253 Gene3D G3DSA:1.10.1660.10 2 139 4.8E-38 T 29-03-2018 CXR48_RS18175 716cfc07405264935bb8402314744156 253 SUPERFAMILY SSF89082 161 245 5.49E-25 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CXR48_RS18175 716cfc07405264935bb8402314744156 253 Gene3D G3DSA:1.10.490.50 153 247 7.6E-25 T 29-03-2018 CXR48_RS18175 716cfc07405264935bb8402314744156 253 SMART SM00422 3 72 9.0E-29 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS18175 716cfc07405264935bb8402314744156 253 Pfam PF07739 TipAS antibiotic-recognition domain 130 243 1.0E-31 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CXR48_RS18175 716cfc07405264935bb8402314744156 253 Pfam PF13411 MerR HTH family regulatory protein 3 69 1.7E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS18175 716cfc07405264935bb8402314744156 253 SUPERFAMILY SSF46955 3 108 6.23E-29 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 SUPERFAMILY SSF52540 530 706 2.2E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 SMART SM00490 564 661 7.3E-9 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 SMART SM00487 262 453 1.6E-26 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 Gene3D G3DSA:3.40.50.300 275 431 4.5E-27 T 29-03-2018 CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 Gene3D G3DSA:3.40.50.300 467 728 3.7E-22 T 29-03-2018 CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 802 26.13 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 SUPERFAMILY SSF52540 235 448 6.68E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 Gene3D G3DSA:1.10.10.10 186 274 7.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 Pfam PF00271 Helicase conserved C-terminal domain 561 660 4.1E-8 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 Pfam PF04851 Type III restriction enzyme, res subunit 265 429 1.7E-17 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CXR48_RS07830 95d62ed6f2e495906fd05e44c4bd3c28 803 TIGRFAM TIGR00595 priA: primosomal protein N' 290 800 5.7E-234 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 Pfam PF00771 FHIPEP family 15 667 2.5E-275 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 29-03-2018 IPR025505 FHIPEP conserved site CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 PIRSF PIRSF005419 1 677 1.4E-261 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 4 675 2.6E-285 T 29-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 2.6E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 2.6E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 2.6E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 2.6E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 2.6E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CXR48_RS08175 a9b6abd1dcb1cf50494a397e19707917 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 2.6E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CXR48_RS10735 ec820c1c972854fce72407d25a0fd7f3 400 Gene3D G3DSA:3.40.50.1100 201 396 4.2E-39 T 29-03-2018 CXR48_RS10735 ec820c1c972854fce72407d25a0fd7f3 400 PIRSF PIRSF001413 2 398 5.2E-162 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CXR48_RS10735 ec820c1c972854fce72407d25a0fd7f3 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 56 379 1.1E-51 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS10735 ec820c1c972854fce72407d25a0fd7f3 400 SUPERFAMILY SSF53686 5 390 3.14E-144 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS10735 ec820c1c972854fce72407d25a0fd7f3 400 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CXR48_RS10735 ec820c1c972854fce72407d25a0fd7f3 400 Gene3D G3DSA:3.40.50.1100 11 200 1.8E-45 T 29-03-2018 CXR48_RS10735 ec820c1c972854fce72407d25a0fd7f3 400 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 390 2.1E-187 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CXR48_RS10735 ec820c1c972854fce72407d25a0fd7f3 400 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 392 52.465 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 Gene3D G3DSA:3.30.1360.80 1 147 3.9E-54 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 148 5.0E-77 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 3.8E-40 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 3.8E-40 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 3.8E-40 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 3.8E-40 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 3.8E-40 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 157 32.424 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 PIRSF PIRSF006160 1 156 5.0E-60 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 150 1.0E-50 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS14195 27f4686af8a458e9a30a03d1835af982 157 SUPERFAMILY SSF63411 4 150 2.38E-58 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 500 2.0E-36 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 SUPERFAMILY SSF51569 3 290 3.3E-97 T 29-03-2018 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 498 2.7E-244 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 Gene3D G3DSA:3.40.50.10090 326 512 0.14 T 29-03-2018 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 510 42.74 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 Gene3D G3DSA:3.20.20.70 1 325 1.6E-111 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 Pfam PF00682 HMGL-like 3 272 1.7E-95 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 SMART SM00917 368 501 9.0E-34 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 SUPERFAMILY SSF110921 397 499 7.06E-20 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CXR48_RS13040 2b2f943a992df95480eb1828feccec5b 518 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 Gene3D G3DSA:3.40.80.10 2 155 2.9E-42 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 Pfam PF01471 Putative peptidoglycan binding domain 226 287 3.2E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 SMART SM00257 160 204 2.0E-21 T 29-03-2018 IPR018392 LysM domain CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 SUPERFAMILY SSF54106 159 204 4.45E-14 T 29-03-2018 IPR018392 LysM domain CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 SMART SM00644 11 153 1.1E-35 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 Gene3D G3DSA:1.10.101.10 218 292 1.0E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 SUPERFAMILY SSF47090 220 289 2.98E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 SUPERFAMILY SSF55846 1 153 1.31E-48 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 Gene3D G3DSA:3.10.350.10 156 209 4.5E-21 T 29-03-2018 CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 25 140 2.7E-24 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS06370 0336e8237ba6545d75c656bfbfc1582b 292 Pfam PF01476 LysM domain 161 203 2.7E-18 T 29-03-2018 IPR018392 LysM domain CXR48_RS01010 2ba5dd10902dd00abf216a0f583e1c9f 335 SUPERFAMILY SSF81345 3 327 5.62E-78 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS01010 2ba5dd10902dd00abf216a0f583e1c9f 335 Gene3D G3DSA:1.10.3470.10 2 334 8.4E-62 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS01010 2ba5dd10902dd00abf216a0f583e1c9f 335 Pfam PF01032 FecCD transport family 18 327 6.3E-86 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CXR48_RS17625 9192fd883426a3be7934829430dc888f 487 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 484 3.2E-288 T 29-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CXR48_RS17625 9192fd883426a3be7934829430dc888f 487 Pfam PF13247 4Fe-4S dicluster domain 172 269 5.9E-37 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CXR48_RS17625 9192fd883426a3be7934829430dc888f 487 SUPERFAMILY SSF54862 2 485 8.48E-161 T 29-03-2018 CXR48_RS17625 9192fd883426a3be7934829430dc888f 487 Gene3D G3DSA:3.30.70.20 196 233 2.2E-17 T 29-03-2018 CXR48_RS17625 9192fd883426a3be7934829430dc888f 487 Gene3D G3DSA:3.30.70.20 368 466 7.3E-26 T 29-03-2018 CXR48_RS17625 9192fd883426a3be7934829430dc888f 487 Gene3D G3DSA:3.30.70.20 234 367 6.8E-31 T 29-03-2018 CXR48_RS17625 9192fd883426a3be7934829430dc888f 487 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 356 436 7.7E-28 T 29-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 CXR48_RS17625 9192fd883426a3be7934829430dc888f 487 Gene3D G3DSA:3.30.70.20 5 195 3.7E-29 T 29-03-2018 CXR48_RS10770 1f26485c7cbbe15c07c9848ef5f15f77 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 369 1.4E-128 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CXR48_RS10770 1f26485c7cbbe15c07c9848ef5f15f77 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CXR48_RS10770 1f26485c7cbbe15c07c9848ef5f15f77 390 PIRSF PIRSF001456 1 384 3.4E-132 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CXR48_RS10770 1f26485c7cbbe15c07c9848ef5f15f77 390 SUPERFAMILY SSF103263 1 388 3.01E-149 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CXR48_RS10770 1f26485c7cbbe15c07c9848ef5f15f77 390 Pfam PF01264 Chorismate synthase 1 364 5.2E-124 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CXR48_RS10770 1f26485c7cbbe15c07c9848ef5f15f77 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CXR48_RS10770 1f26485c7cbbe15c07c9848ef5f15f77 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CXR48_RS10770 1f26485c7cbbe15c07c9848ef5f15f77 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 36.517 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CXR48_RS10770 1f26485c7cbbe15c07c9848ef5f15f77 390 Gene3D G3DSA:3.60.150.10 1 390 2.8E-143 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CXR48_RS05570 d596588f5e13bf16b274a2e6e47232a1 261 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 67 258 1.4E-61 T 29-03-2018 IPR018728 Domain of unknown function DUF2268 CXR48_RS03050 f4803d9012e1994588530f3e18b03414 170 Pfam PF01967 MoaC family 15 152 4.6E-52 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CXR48_RS03050 f4803d9012e1994588530f3e18b03414 170 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 6.2E-66 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CXR48_RS03050 f4803d9012e1994588530f3e18b03414 170 SUPERFAMILY SSF55040 11 157 9.15E-56 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CXR48_RS03050 f4803d9012e1994588530f3e18b03414 170 Gene3D G3DSA:3.30.70.640 2 160 4.0E-66 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CXR48_RS03050 f4803d9012e1994588530f3e18b03414 170 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 160 35.106 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CXR48_RS10465 54f94d220ea40ad3bc3a8d39a25c1ffd 194 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 42.368 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CXR48_RS10465 54f94d220ea40ad3bc3a8d39a25c1ffd 194 SUPERFAMILY SSF53271 2 189 8.52E-47 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS10465 54f94d220ea40ad3bc3a8d39a25c1ffd 194 Pfam PF00156 Phosphoribosyl transferase domain 35 159 8.4E-9 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CXR48_RS10465 54f94d220ea40ad3bc3a8d39a25c1ffd 194 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 2 191 5.0E-93 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CXR48_RS10465 54f94d220ea40ad3bc3a8d39a25c1ffd 194 Gene3D G3DSA:3.40.50.2020 3 188 8.3E-25 T 29-03-2018 CXR48_RS03305 f7d94ad74bad2c3e196899707cb263d3 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 334 1.2E-149 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS03305 f7d94ad74bad2c3e196899707cb263d3 346 Gene3D G3DSA:3.30.1330.10 29 158 8.5E-54 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03305 f7d94ad74bad2c3e196899707cb263d3 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 72 160 1.3E-16 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03305 f7d94ad74bad2c3e196899707cb263d3 346 SUPERFAMILY SSF55326 4 166 1.27E-48 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03305 f7d94ad74bad2c3e196899707cb263d3 346 Gene3D G3DSA:3.90.650.10 168 340 2.4E-62 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03305 f7d94ad74bad2c3e196899707cb263d3 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 343 47.882 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS03305 f7d94ad74bad2c3e196899707cb263d3 346 SUPERFAMILY SSF56042 169 338 1.45E-58 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03305 f7d94ad74bad2c3e196899707cb263d3 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 338 1.1E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS07260 9855ec28264ca8532dc0189d8c872a49 363 Pfam PF00144 Beta-lactamase 22 342 7.5E-49 T 29-03-2018 IPR001466 Beta-lactamase-related CXR48_RS07260 9855ec28264ca8532dc0189d8c872a49 363 Gene3D G3DSA:3.40.710.10 9 355 6.9E-66 T 29-03-2018 CXR48_RS07260 9855ec28264ca8532dc0189d8c872a49 363 SUPERFAMILY SSF56601 16 357 7.05E-70 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 Gene3D G3DSA:3.10.290.10 327 421 1.4E-22 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 Gene3D G3DSA:3.40.50.620 4 225 1.6E-66 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 SUPERFAMILY SSF55174 323 420 2.75E-25 T 29-03-2018 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 1 420 1.1E-149 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 SMART SM00363 356 417 5.0E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 Gene3D G3DSA:1.10.240.10 226 326 9.9E-38 T 29-03-2018 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 421 46.542 T 29-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 Pfam PF00579 tRNA synthetases class I (W and Y) 29 325 4.0E-92 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 6.5E-32 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 6.5E-32 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 6.5E-32 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 218 230 6.5E-32 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 SUPERFAMILY SSF52374 2 325 1.62E-105 T 29-03-2018 CXR48_RS13755 8a2a699c8c56b150b5ab8ef79497d7bb 421 Pfam PF01479 S4 domain 357 402 8.4E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS06175 7755acb2faf418ff923767221d14d9ee 125 Gene3D G3DSA:2.30.29.50 13 101 1.7E-37 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CXR48_RS06175 7755acb2faf418ff923767221d14d9ee 125 SUPERFAMILY SSF50729 6 124 1.68E-41 T 29-03-2018 IPR011993 PH domain-like CXR48_RS06175 7755acb2faf418ff923767221d14d9ee 125 Pfam PF08000 Bacterial PH domain 3 123 1.0E-48 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SMART SM00823 Phosphopantetheine attachment site 769 838 0.0055 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SMART SM00823 Phosphopantetheine attachment site 3307 3376 0.1 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2945 2956 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF56801 225 781 1.7E-136 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF47336 3301 3373 3.14E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF47336 1797 1869 6.67E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF52777 3393 3578 1.67E-9 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.30.559.10 837 1039 3.8E-31 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.30.559.10 2335 2550 1.3E-31 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.40.50.980 1295 1448 2.5E-46 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.40.50.980 256 411 1.3E-36 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.40.50.980 2797 2950 2.3E-45 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:1.10.1200.10 1809 1872 8.1E-13 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF52777 2350 2527 1.26E-38 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF52777 2528 2772 1.11E-46 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:1.10.1200.10 3314 3377 1.8E-14 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF47336 761 834 1.28E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF52777 857 1018 3.26E-35 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF13193 AMP-binding enzyme C-terminal domain 673 742 1.0E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF13193 AMP-binding enzyme C-terminal domain 3206 3279 3.7E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF13193 AMP-binding enzyme C-terminal domain 1705 1778 1.4E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF52777 2069 2313 1.67E-34 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:2.30.38.10 1607 1687 9.3E-20 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:2.30.38.10 3110 3188 3.1E-25 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.30.559.10 1873 2072 2.3E-27 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1829 1844 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2827 3222 5.6E-130 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 286 689 1.3E-116 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1325 1721 1.0E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF52777 1887 2062 1.67E-35 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00550 Phosphopantetheine attachment site 770 834 1.9E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00550 Phosphopantetheine attachment site 1808 1869 3.5E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00550 Phosphopantetheine attachment site 3310 3372 1.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 ProSitePatterns PS00455 Putative AMP-binding domain signature. 405 416 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:2.30.38.10 576 658 4.4E-26 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF56801 2765 3320 4.45E-143 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.30.300.30 660 774 1.6E-32 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.30.300.30 1692 1808 3.1E-34 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.30.300.30 3193 3313 9.2E-28 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.40.50.980 412 571 1.1E-25 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.40.50.980 1449 1605 4.8E-30 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:3.40.50.980 2951 3109 1.1E-34 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1443 1454 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00501 AMP-binding enzyme 2806 3198 6.8E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00501 AMP-binding enzyme 265 665 1.6E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00501 AMP-binding enzyme 1304 1697 4.5E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF56801 1266 1817 5.49E-142 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2189 2337 4.2E-44 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00668 Condensation domain 2345 2786 6.5E-109 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00668 Condensation domain 1882 2320 6.6E-100 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00668 Condensation domain 851 1284 5.3E-116 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Pfam PF00668 Condensation domain 15 245 1.6E-43 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 Gene3D G3DSA:1.10.1200.10 775 836 2.1E-21 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF52777 17 237 8.12E-37 T 29-03-2018 CXR48_RS01195 26b62fa7252df90c351ef50041cbc2be 3584 SUPERFAMILY SSF52777 1025 1289 3.56E-56 T 29-03-2018 CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 212.347 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 SMART SM00788 3 422 4.1E-292 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 Gene3D G3DSA:3.40.440.10 150 264 4.4E-29 T 29-03-2018 CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 Gene3D G3DSA:3.40.440.10 1 149 6.1E-53 T 29-03-2018 CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.1E-184 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 SUPERFAMILY SSF52540 1 427 7.75E-175 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 Gene3D G3DSA:3.90.170.10 265 429 3.6E-68 T 29-03-2018 CXR48_RS19060 ee378df736eb44dfa6dae39c7447d64c 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 5.1E-202 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CXR48_RS15520 f08f41ef96daff1e0e96c609f3417e16 189 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 180 1.0E-66 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CXR48_RS15520 f08f41ef96daff1e0e96c609f3417e16 189 Gene3D G3DSA:1.20.1200.10 12 186 1.8E-61 T 29-03-2018 CXR48_RS15520 f08f41ef96daff1e0e96c609f3417e16 189 Pfam PF01923 Cobalamin adenosyltransferase 4 166 3.9E-59 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CXR48_RS15520 f08f41ef96daff1e0e96c609f3417e16 189 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 178 5.2E-67 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CXR48_RS15520 f08f41ef96daff1e0e96c609f3417e16 189 SUPERFAMILY SSF89028 1 179 2.35E-66 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF52777 684 856 3.78E-33 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF56801 1105 1662 9.03E-155 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00823 Phosphopantetheine attachment site 4418 4489 1.8E-8 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00823 Phosphopantetheine attachment site 3096 3167 6.6E-14 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00823 Phosphopantetheine attachment site 1650 1719 2.0E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00823 Phosphopantetheine attachment site 3189 3260 5.4E-12 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00823 Phosphopantetheine attachment site 586 657 8.6E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF47336 3095 3167 1.22E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3469 3485 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00825 Beta-ketoacyl synthase 1753 2179 3.2E-140 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00825 Beta-ketoacyl synthase 4535 4939 4.9E-108 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00825 Beta-ketoacyl synthase 3309 3747 2.4E-200 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:1.10.1200.10 562 662 1.5E-16 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1290 1301 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.47.10 4525 4777 2.2E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.47.10 3300 3568 1.2E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.50.980 1296 1443 2.8E-36 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.50.980 198 363 2.1E-28 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF51735 4128 4391 6.23E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4773 4887 1.6E-31 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2008 2126 5.6E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3564 3688 2.4E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF47336 1646 1765 7.85E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.30.559.10 663 865 4.0E-28 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.50.720 4123 4390 9.7E-37 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.50.720 2821 3089 1.5E-40 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1674 1689 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF53901 4531 4880 1.88E-68 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 ProSitePatterns PS00012 Phosphopantetheine attachment site. 612 627 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.47.10 2015 2177 8.7E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.47.10 3572 3745 1.0E-53 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.47.10 4780 4937 3.2E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF08659 KR domain 2829 3014 8.3E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF08659 KR domain 4131 4327 2.2E-41 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF51735 3934 4110 3.03E-9 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2129 2240 2.1E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3692 3791 2.8E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:1.10.1200.10 4392 4491 7.0E-15 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF47336 4417 4490 1.06E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF47336 4533 4547 1.06E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM01294 4419 4485 8.0E-10 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM01294 3190 3256 5.5E-5 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM01294 3097 3163 9.0E-5 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM01294 588 653 3.1E-4 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF51735 2828 3034 1.28E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.10.129.10 2360 2487 1.0E-16 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.30.300.30 1535 1654 1.3E-35 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4533 4765 2.8E-63 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3307 3556 7.6E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1751 2000 6.7E-62 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00826 2358 2523 3.3E-18 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00501 AMP-binding enzyme 52 456 5.9E-66 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00501 AMP-binding enzyme 1146 1540 4.7E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF14765 Polyketide synthase dehydratase 2358 2644 5.0E-60 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF47336 583 663 5.23E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2829 3015 9.0E-48 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4129 4328 7.0E-40 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4678 4694 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF53901 1896 2119 4.4E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF53901 1749 1868 4.4E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF53901 2154 2175 4.4E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00668 Condensation domain 682 1126 3.6E-106 T 29-03-2018 IPR001242 Condensation domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:1.10.1200.10 3090 3184 2.3E-14 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:1.10.1200.10 1655 1748 1.5E-18 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:1.10.1200.10 3185 3299 3.2E-16 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00550 Phosphopantetheine attachment site 3191 3256 1.9E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00550 Phosphopantetheine attachment site 1652 1715 8.0E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00550 Phosphopantetheine attachment site 4419 4485 3.5E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00550 Phosphopantetheine attachment site 3099 3163 2.0E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF00550 Phosphopantetheine attachment site 592 652 8.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF56801 23 561 6.54E-99 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Pfam PF13193 AMP-binding enzyme C-terminal domain 1549 1623 1.4E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1167 1564 4.6E-124 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.47.10 1749 2011 2.7E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF47336 3291 3321 1.18E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF47336 3183 3261 1.18E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4444 4459 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF52777 863 1132 2.22E-46 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF53901 3723 3741 9.26E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 SUPERFAMILY SSF53901 3304 3681 9.26E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:2.30.38.10 1444 1532 6.8E-21 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:2.30.38.10 364 448 2.3E-21 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.50.980 26 197 6.1E-26 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.40.50.980 1138 1295 1.5E-48 T 29-03-2018 CXR48_RS08560 821cf966c868f27a30da6d79252f5af0 4984 Gene3D G3DSA:3.30.300.30 449 559 7.8E-13 T 29-03-2018 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 SMART SM01240 9 474 0.0 T 29-03-2018 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 86.098 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 Gene3D G3DSA:3.20.20.70 3 484 8.6E-115 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 SUPERFAMILY SSF51412 220 478 5.63E-127 T 29-03-2018 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 SUPERFAMILY SSF51412 6 92 5.63E-127 T 29-03-2018 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 Pfam PF00571 CBS domain 153 204 3.9E-9 T 29-03-2018 IPR000644 CBS domain CXR48_RS00070 72500279437ed86dca9191aa37686997 488 Pfam PF00571 CBS domain 97 144 1.2E-7 T 29-03-2018 IPR000644 CBS domain CXR48_RS00070 72500279437ed86dca9191aa37686997 488 SMART SM00116 161 209 5.8E-9 T 29-03-2018 IPR000644 CBS domain CXR48_RS00070 72500279437ed86dca9191aa37686997 488 SMART SM00116 98 148 1.3E-8 T 29-03-2018 IPR000644 CBS domain CXR48_RS00070 72500279437ed86dca9191aa37686997 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 4.4E-208 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 1.0E-168 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 SUPERFAMILY SSF54631 66 208 6.36E-32 T 29-03-2018 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CXR48_RS00070 72500279437ed86dca9191aa37686997 488 PIRSF PIRSF000130 1 488 9.4E-213 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CXR48_RS12135 f72c43d3f967bb2101b881ba26bb3dad 255 TIGRFAM TIGR00613 reco: DNA repair protein RecO 3 243 4.1E-86 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CXR48_RS12135 f72c43d3f967bb2101b881ba26bb3dad 255 Gene3D G3DSA:2.40.50.140 1 81 1.8E-24 T 29-03-2018 CXR48_RS12135 f72c43d3f967bb2101b881ba26bb3dad 255 SUPERFAMILY SSF50249 1 75 4.11E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS12135 f72c43d3f967bb2101b881ba26bb3dad 255 SUPERFAMILY SSF57863 81 231 3.4E-46 T 29-03-2018 CXR48_RS12135 f72c43d3f967bb2101b881ba26bb3dad 255 Pfam PF11967 Recombination protein O N terminal 1 76 1.7E-26 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CXR48_RS12135 f72c43d3f967bb2101b881ba26bb3dad 255 Pfam PF02565 Recombination protein O C terminal 82 238 7.2E-41 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CXR48_RS12135 f72c43d3f967bb2101b881ba26bb3dad 255 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 30.089 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CXR48_RS15215 c87bda458dda16f5b94005f924fa2345 328 Pfam PF01380 SIS domain 25 125 7.4E-13 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CXR48_RS15215 c87bda458dda16f5b94005f924fa2345 328 SUPERFAMILY SSF53697 22 328 1.21E-59 T 29-03-2018 CXR48_RS15215 c87bda458dda16f5b94005f924fa2345 328 PIRSF PIRSF009290 2 328 1.2E-92 T 29-03-2018 IPR024713 Fructosamine deglycase FrlB CXR48_RS15215 c87bda458dda16f5b94005f924fa2345 328 Gene3D G3DSA:3.40.50.10490 175 327 6.9E-16 T 29-03-2018 CXR48_RS15215 c87bda458dda16f5b94005f924fa2345 328 Gene3D G3DSA:3.40.50.10490 1 154 2.4E-27 T 29-03-2018 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 464 9.2E-199 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 Gene3D G3DSA:3.40.50.620 1 305 5.2E-94 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 4.9E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.9E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.9E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 4.9E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 Gene3D G3DSA:1.20.120.640 306 407 2.4E-21 T 29-03-2018 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 SUPERFAMILY SSF52374 4 314 5.09E-103 T 29-03-2018 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 39.021 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 SMART SM00840 353 416 3.2E-18 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 SUPERFAMILY SSF47323 320 464 9.48E-36 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 Pfam PF09190 DALR domain 353 412 1.1E-16 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CXR48_RS00625 975d10df1524fa0c9277c02f7f260e8a 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 2.5E-140 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CXR48_RS16075 d7c11b93ba46dc1dc09181c24da9b011 446 Pfam PF00324 Amino acid permease 16 421 6.4E-98 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS16075 d7c11b93ba46dc1dc09181c24da9b011 446 PIRSF PIRSF006060 1 445 3.9E-72 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS03855 2f43c463e8150f1484fe54d6db08bd4b 294 Gene3D G3DSA:3.40.50.10860 2 122 1.2E-44 T 29-03-2018 CXR48_RS03855 2f43c463e8150f1484fe54d6db08bd4b 294 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 17 99 2.3E-28 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CXR48_RS03855 2f43c463e8150f1484fe54d6db08bd4b 294 SUPERFAMILY SSF53223 8 111 1.15E-34 T 29-03-2018 CXR48_RS03855 2f43c463e8150f1484fe54d6db08bd4b 294 Gene3D G3DSA:3.40.50.720 123 294 1.4E-29 T 29-03-2018 CXR48_RS03855 2f43c463e8150f1484fe54d6db08bd4b 294 SUPERFAMILY SSF51735 112 292 4.34E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS03855 2f43c463e8150f1484fe54d6db08bd4b 294 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 14 292 6.9E-62 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CXR48_RS03855 2f43c463e8150f1484fe54d6db08bd4b 294 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 12 294 32.985 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CXR48_RS10760 d7154ff0bac8e82ae72c7f3f8a819752 127 Pfam PF07736 Chorismate mutase type I 3 119 2.0E-48 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CXR48_RS10760 d7154ff0bac8e82ae72c7f3f8a819752 127 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 127 8.0E-55 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CXR48_RS10760 d7154ff0bac8e82ae72c7f3f8a819752 127 PIRSF PIRSF005965 1 125 2.0E-52 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CXR48_RS10760 d7154ff0bac8e82ae72c7f3f8a819752 127 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 119 2.9E-48 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CXR48_RS10760 d7154ff0bac8e82ae72c7f3f8a819752 127 Gene3D G3DSA:3.30.1330.40 3 120 4.5E-50 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CXR48_RS10760 d7154ff0bac8e82ae72c7f3f8a819752 127 SUPERFAMILY SSF55298 1 126 4.39E-50 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 467 6.5E-137 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 SUPERFAMILY SSF48179 176 468 5.44E-133 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 468 3.1E-232 T 29-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 SUPERFAMILY SSF51735 4 176 5.99E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 29-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 PIRSF PIRSF000109 1 469 3.2E-245 T 29-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 Gene3D G3DSA:1.20.5.320 436 469 1.2E-21 T 29-03-2018 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 SMART SM01350 178 468 5.0E-232 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 8.4E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 8.4E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 8.4E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 8.4E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 8.4E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 8.4E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 Gene3D G3DSA:3.40.50.720 1 179 1.7E-36 T 29-03-2018 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 Gene3D G3DSA:1.10.1040.10 180 435 8.0E-114 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS11440 06301f667b9868629fbdfbe5737a1692 469 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 167 1.4E-54 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CXR48_RS04055 637973ea0e3ad9cc1b60b3ce4b2261cb 803 SUPERFAMILY SSF52009 675 788 1.7E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS04055 637973ea0e3ad9cc1b60b3ce4b2261cb 803 Pfam PF00391 PEP-utilising enzyme, mobile domain 711 781 1.1E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS04055 637973ea0e3ad9cc1b60b3ce4b2261cb 803 Gene3D G3DSA:3.30.470.20 146 248 3.0E-28 T 29-03-2018 CXR48_RS04055 637973ea0e3ad9cc1b60b3ce4b2261cb 803 SUPERFAMILY SSF56059 1 289 9.65E-63 T 29-03-2018 CXR48_RS04055 637973ea0e3ad9cc1b60b3ce4b2261cb 803 Gene3D G3DSA:3.50.30.10 683 801 3.8E-33 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS04055 637973ea0e3ad9cc1b60b3ce4b2261cb 803 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 207 252 3.8E-8 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CXR48_RS04055 637973ea0e3ad9cc1b60b3ce4b2261cb 803 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 46 197 4.1E-34 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CXR48_RS04055 637973ea0e3ad9cc1b60b3ce4b2261cb 803 Gene3D G3DSA:3.30.1490.20 57 145 7.1E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS04055 637973ea0e3ad9cc1b60b3ce4b2261cb 803 Gene3D G3DSA:3.30.1490.20 1 56 9.7E-6 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS18540 cbba72c3df237b132ab7d7d97bcd1c94 354 Pfam PF00544 Pectate lyase 101 283 1.9E-42 T 29-03-2018 IPR002022 Pectate lyase CXR48_RS18540 cbba72c3df237b132ab7d7d97bcd1c94 354 SMART SM00656 65 289 1.1E-46 T 29-03-2018 IPR002022 Pectate lyase CXR48_RS18540 cbba72c3df237b132ab7d7d97bcd1c94 354 Gene3D G3DSA:2.160.20.10 101 350 1.3E-28 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS18540 cbba72c3df237b132ab7d7d97bcd1c94 354 Gene3D G3DSA:2.160.20.10 21 100 7.3E-7 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS18540 cbba72c3df237b132ab7d7d97bcd1c94 354 SUPERFAMILY SSF51126 44 349 5.39E-56 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 SUPERFAMILY SSF52518 15 192 1.97E-61 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 207 342 1.4E-44 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 400 548 1.4E-53 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 18 182 1.8E-55 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 Gene3D G3DSA:3.40.50.1220 211 360 1.9E-51 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 18 572 1.4E-279 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 Gene3D G3DSA:3.40.50.970 361 564 1.0E-52 T 29-03-2018 CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 SUPERFAMILY SSF52467 200 368 3.41E-62 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 Gene3D G3DSA:3.40.50.970 11 210 7.6E-62 T 29-03-2018 CXR48_RS13055 316ea093aad044c9cd27f282795b8958 574 SUPERFAMILY SSF52518 376 572 2.32E-68 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 SMART SM00534 328 513 2.2E-86 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 SUPERFAMILY SSF52540 292 512 5.97E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 SMART SM00533 9 315 7.8E-48 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 SMART SM00463 707 785 2.4E-21 T 29-03-2018 IPR002625 Smr domain CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 784 22.56 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 Gene3D G3DSA:1.10.1420.10 17 290 7.3E-8 T 29-03-2018 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 Pfam PF05192 MutS domain III 34 282 1.1E-6 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 Gene3D G3DSA:3.40.50.300 291 513 7.8E-37 T 29-03-2018 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 Pfam PF01713 Smr domain 710 785 9.9E-20 T 29-03-2018 IPR002625 Smr domain CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 SUPERFAMILY SSF160443 708 785 4.18E-9 T 29-03-2018 IPR002625 Smr domain CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 TIGRFAM TIGR01069 mutS2: MutS2 family protein 2 785 0.0 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 Pfam PF00488 MutS domain V 331 512 1.7E-37 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 PIRSF PIRSF005814 1 785 1.0E-290 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 Gene3D G3DSA:1.20.5.1230 514 760 0.0026 T 29-03-2018 CXR48_RS13200 3a3b43e193720e5a874ed185bf45da37 785 SUPERFAMILY SSF48334 21 288 1.7E-29 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CXR48_RS05460 15d7d8a35e40f89b181d1e7ac855d95b 255 Pfam PF00326 Prolyl oligopeptidase family 101 255 5.4E-9 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CXR48_RS05460 15d7d8a35e40f89b181d1e7ac855d95b 255 SUPERFAMILY SSF53474 21 255 2.22E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS05460 15d7d8a35e40f89b181d1e7ac855d95b 255 Gene3D G3DSA:3.40.50.1820 4 255 4.6E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 3.5E-39 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 SUPERFAMILY SSF52794 171 273 8.55E-38 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 SUPERFAMILY SSF55804 2 148 1.12E-44 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 148 2.0E-39 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 Gene3D G3DSA:3.40.50.2300 171 267 2.1E-39 T 29-03-2018 CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 174 255 7.7E-31 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 Gene3D G3DSA:3.40.930.10 1 150 1.1E-45 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 299 628 1.9E-127 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CXR48_RS07110 ac6d52fa4f9aeaebe41b78ed77e3bcc9 634 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 174 263 8.8E-18 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 SUPERFAMILY SSF53383 3 391 4.12E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 1.8E-16 T 29-03-2018 CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 1.8E-16 T 29-03-2018 CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 1.8E-16 T 29-03-2018 CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 1.8E-16 T 29-03-2018 CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 1.8E-16 T 29-03-2018 CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 Gene3D G3DSA:3.40.640.10 44 271 2.0E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 Pfam PF00155 Aminotransferase class I and II 31 385 1.6E-80 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS10595 9c73eff9681489cce5ab30b3f138d94b 393 Gene3D G3DSA:3.90.1150.10 272 393 4.2E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 10 498 5.1E-234 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 SUPERFAMILY SSF50249 10 151 3.86E-46 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 SUPERFAMILY SSF55681 158 497 2.49E-125 T 29-03-2018 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 17 499 46.631 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 PIRSF PIRSF039101 1 499 5.3E-205 T 29-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 Gene3D G3DSA:3.30.930.10 152 496 2.9E-111 T 29-03-2018 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 Gene3D G3DSA:2.40.50.140 11 151 2.3E-44 T 29-03-2018 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 Pfam PF01336 OB-fold nucleic acid binding domain 65 142 7.6E-16 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 Pfam PF00152 tRNA synthetases class II (D, K and N) 159 496 1.7E-84 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 211 227 4.0E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 240 253 4.0E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 258 275 4.0E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 195 205 4.0E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CXR48_RS00485 5eb3288842f121dcb0216db9d7884d87 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 381 397 4.0E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CXR48_RS13395 06d0f38410e9d4a4fc954a13038cc36a 469 Gene3D G3DSA:1.10.10.630 321 394 1.8E-13 T 29-03-2018 IPR034829 DnaD-like domain CXR48_RS13395 06d0f38410e9d4a4fc954a13038cc36a 469 Pfam PF07261 Replication initiation and membrane attachment 329 394 1.5E-11 T 29-03-2018 IPR006343 DnaD domain CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 SUPERFAMILY SSF54570 3 84 2.35E-35 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 PIRSF PIRSF002144 1 92 4.3E-32 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 Pfam PF00203 Ribosomal protein S19 3 83 8.4E-36 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 Gene3D G3DSA:3.30.860.10 1 92 1.4E-40 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.8E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.8E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.8E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 5.7E-48 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CXR48_RS00755 d48e274fe6a31501d4887f4975c5cd5d 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.418 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS15090 bd7c679ff7867e64b2c140a1115d0b8a 144 Pfam PF01934 Protein of unknown function DUF86 25 127 1.8E-21 T 29-03-2018 IPR008201 Protein of unknown function DUF86 CXR48_RS15090 bd7c679ff7867e64b2c140a1115d0b8a 144 Gene3D G3DSA:1.20.120.580 1 144 1.6E-33 T 29-03-2018 IPR008201 Protein of unknown function DUF86 CXR48_RS12895 0a2b95847616c58eccebb164c4c168fd 226 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 108 206 2.7E-30 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CXR48_RS12895 0a2b95847616c58eccebb164c4c168fd 226 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 8 209 6.7E-53 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CXR48_RS12895 0a2b95847616c58eccebb164c4c168fd 226 Gene3D G3DSA:3.30.750.50 9 96 9.8E-27 T 29-03-2018 CXR48_RS12895 0a2b95847616c58eccebb164c4c168fd 226 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 210 22.162 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CXR48_RS12895 0a2b95847616c58eccebb164c4c168fd 226 Gene3D G3DSA:2.160.20.70 97 213 1.1E-38 T 29-03-2018 CXR48_RS12895 0a2b95847616c58eccebb164c4c168fd 226 SUPERFAMILY SSF63848 106 210 9.68E-30 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 Pfam PF02743 Cache domain 43 263 2.1E-29 T 29-03-2018 IPR033479 Double Cache domain 1 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 SMART SM00283 384 659 1.4E-96 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 Gene3D G3DSA:1.10.287.950 418 661 1.0E-58 T 29-03-2018 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 Gene3D G3DSA:3.30.450.20 36 171 7.6E-18 T 29-03-2018 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 SUPERFAMILY SSF58104 390 659 2.09E-73 T 29-03-2018 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 SUPERFAMILY SSF58104 323 357 2.09E-73 T 29-03-2018 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 Gene3D G3DSA:1.10.287.950 329 417 1.1E-8 T 29-03-2018 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 Gene3D G3DSA:3.30.450.20 172 277 5.7E-18 T 29-03-2018 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 SMART SM00304 303 355 3.6E-16 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 612 5.3E-60 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 Pfam PF00672 HAMP domain 303 351 2.8E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 SMART SM00319 33 151 2.7E-27 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CXR48_RS14495 30b2109673b70e88266eab0a6915b60d 661 SUPERFAMILY SSF103190 87 191 7.06E-11 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS04600 03ff935f4dc429f3669dcd7590d8fa2c 140 SMART SM00116 75 122 9.9E-11 T 29-03-2018 IPR000644 CBS domain CXR48_RS04600 03ff935f4dc429f3669dcd7590d8fa2c 140 SMART SM00116 11 58 2.7E-14 T 29-03-2018 IPR000644 CBS domain CXR48_RS04600 03ff935f4dc429f3669dcd7590d8fa2c 140 SUPERFAMILY SSF54631 3 117 2.53E-35 T 29-03-2018 CXR48_RS04600 03ff935f4dc429f3669dcd7590d8fa2c 140 Gene3D G3DSA:3.10.580.10 2 138 4.3E-33 T 29-03-2018 CXR48_RS04600 03ff935f4dc429f3669dcd7590d8fa2c 140 Pfam PF00571 CBS domain 8 54 2.4E-13 T 29-03-2018 IPR000644 CBS domain CXR48_RS04600 03ff935f4dc429f3669dcd7590d8fa2c 140 Pfam PF00571 CBS domain 68 118 7.6E-11 T 29-03-2018 IPR000644 CBS domain CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 PIRSF PIRSF000497 1 398 3.1E-181 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 SUPERFAMILY SSF55973 247 395 5.49E-70 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 1.3E-70 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 4.8E-191 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 Gene3D G3DSA:3.30.300.10 146 247 5.7E-49 T 29-03-2018 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 SUPERFAMILY SSF55973 125 246 5.89E-54 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 8.2E-51 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 SUPERFAMILY SSF55973 5 111 1.29E-47 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 60.809 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 Gene3D G3DSA:3.30.300.10 13 145 8.0E-46 T 29-03-2018 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 Gene3D G3DSA:3.30.300.10 260 399 9.0E-49 T 29-03-2018 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 3.5E-44 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS14135 97f0d09011444a00a59c07ed0968bfdc 400 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CXR48_RS16005 5cece69cd3b48b08620e87329cc6615f 426 SUPERFAMILY SSF53187 28 89 5.59E-50 T 29-03-2018 CXR48_RS16005 5cece69cd3b48b08620e87329cc6615f 426 SUPERFAMILY SSF53187 213 422 5.59E-50 T 29-03-2018 CXR48_RS16005 5cece69cd3b48b08620e87329cc6615f 426 Gene3D G3DSA:3.40.630.10 23 426 3.3E-49 T 29-03-2018 CXR48_RS16005 5cece69cd3b48b08620e87329cc6615f 426 Pfam PF04389 Peptidase family M28 221 419 1.3E-37 T 29-03-2018 IPR007484 Peptidase M28 CXR48_RS16005 5cece69cd3b48b08620e87329cc6615f 426 SUPERFAMILY SSF52025 111 207 1.23E-13 T 29-03-2018 CXR48_RS16005 5cece69cd3b48b08620e87329cc6615f 426 Pfam PF02225 PA domain 127 201 6.4E-14 T 29-03-2018 IPR003137 PA domain CXR48_RS08555 217f56167309617a16becfb0dd2e5bde 249 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CXR48_RS08555 217f56167309617a16becfb0dd2e5bde 249 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 244 6.4E-65 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CXR48_RS08555 217f56167309617a16becfb0dd2e5bde 249 SUPERFAMILY SSF52096 8 244 5.32E-44 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS08555 217f56167309617a16becfb0dd2e5bde 249 Gene3D G3DSA:3.90.226.10 3 247 5.6E-39 T 29-03-2018 CXR48_RS08665 08d1dd10268700f8145623254302fb01 130 Hamap MF_00128 Protein NrdI [nrdI]. 2 122 27.118 T 29-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial CXR48_RS08665 08d1dd10268700f8145623254302fb01 130 Pfam PF07972 NrdI Flavodoxin like 4 112 3.0E-31 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CXR48_RS08665 08d1dd10268700f8145623254302fb01 130 PIRSF PIRSF005087 1 126 1.6E-39 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CXR48_RS08665 08d1dd10268700f8145623254302fb01 130 SUPERFAMILY SSF52218 2 121 5.91E-24 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS08665 08d1dd10268700f8145623254302fb01 130 Gene3D G3DSA:3.40.50.360 2 121 2.5E-19 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS08665 08d1dd10268700f8145623254302fb01 130 TIGRFAM TIGR00333 nrdI: nrdI protein 4 125 2.7E-49 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 SUPERFAMILY SSF82679 2 114 2.88E-41 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 SMART SM00738 2 113 7.3E-54 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 SMART SM00739 123 150 2.2E-6 T 29-03-2018 IPR005824 KOW CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 Gene3D G3DSA:3.30.70.940 2 116 5.1E-45 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 Pfam PF02357 Transcription termination factor nusG 3 109 1.8E-28 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.3E-21 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.3E-21 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.3E-21 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 SUPERFAMILY SSF50104 121 177 1.12E-19 T 29-03-2018 IPR008991 Translation protein SH3-like domain CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 Pfam PF00467 KOW motif 128 158 3.4E-8 T 29-03-2018 IPR005824 KOW CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 Gene3D G3DSA:2.30.30.30 118 177 3.7E-22 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 5.2E-69 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CXR48_RS00660 9d098af3b14e14a461fb1da34c210a16 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 30.634 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CXR48_RS10810 b6acc7c928a58dea98a1223257dc0366 92 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.3E-38 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CXR48_RS10810 b6acc7c928a58dea98a1223257dc0366 92 Gene3D G3DSA:4.10.520.10 1 92 1.6E-40 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CXR48_RS10810 b6acc7c928a58dea98a1223257dc0366 92 SUPERFAMILY SSF47729 1 90 1.62E-36 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CXR48_RS10810 b6acc7c928a58dea98a1223257dc0366 92 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.2E-22 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CXR48_RS10810 b6acc7c928a58dea98a1223257dc0366 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.2E-22 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CXR48_RS10810 b6acc7c928a58dea98a1223257dc0366 92 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.2E-22 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CXR48_RS10810 b6acc7c928a58dea98a1223257dc0366 92 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CXR48_RS10810 b6acc7c928a58dea98a1223257dc0366 92 SMART SM00411 1 90 7.2E-54 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:3.30.559.10 836 1034 1.3E-29 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF00668 Condensation domain 1315 1758 8.0E-115 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF00668 Condensation domain 3 249 3.5E-11 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF00668 Condensation domain 848 1290 2.6E-103 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SMART SM00823 Phosphopantetheine attachment site 2292 2361 0.007 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SMART SM00823 Phosphopantetheine attachment site 769 837 0.14 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:2.30.38.10 2095 2178 2.6E-24 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF47336 2284 2357 7.59E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF00550 Phosphopantetheine attachment site 2294 2357 2.0E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF00550 Phosphopantetheine attachment site 772 830 4.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1800 2209 1.2E-144 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 290 687 6.7E-134 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 ProSitePatterns PS00012 Phosphopantetheine attachment site. 793 808 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1153 1303 1.4E-43 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF00501 AMP-binding enzyme 269 663 3.1E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF00501 AMP-binding enzyme 1779 2185 3.8E-112 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:2.30.38.10 566 655 2.2E-24 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:3.40.50.980 1770 1923 4.0E-52 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:3.40.50.980 260 413 3.3E-48 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1918 1929 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF47336 761 833 3.8E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF53474 2368 2586 2.78E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF13193 AMP-binding enzyme C-terminal domain 2193 2265 1.3E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF13193 AMP-binding enzyme C-terminal domain 671 743 5.1E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF52777 1031 1286 5.0E-38 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF52777 851 1025 1.02E-38 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF52777 1498 1748 2.0E-51 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Pfam PF00975 Thioesterase domain 2380 2480 7.3E-22 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:3.40.50.980 414 565 8.0E-25 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:3.40.50.980 1924 2094 1.5E-38 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:1.10.1200.10 2295 2366 2.6E-16 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:1.10.1200.10 775 835 3.5E-18 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF56801 1738 2304 7.98E-169 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2316 2331 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SMART SM00824 Thioesterase 2382 2539 3.4E-5 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF52777 1312 1513 3.56E-44 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF56801 230 781 3.27E-146 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:3.40.50.1820 2367 2587 3.8E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:3.30.300.30 2180 2294 7.3E-36 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:3.30.300.30 658 774 1.1E-35 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 Gene3D G3DSA:3.30.559.10 1294 1519 2.7E-37 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 SUPERFAMILY SSF52777 3 237 5.34E-15 T 29-03-2018 CXR48_RS09095 1d20ae21821337389e948aa2f3c0a7b9 2617 ProSitePatterns PS00455 Putative AMP-binding domain signature. 408 419 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09145 27ec7273be4dd4b22264563e9ae8b075 339 TIGRFAM TIGR00433 bioB: biotin synthase 27 320 4.1E-119 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CXR48_RS09145 27ec7273be4dd4b22264563e9ae8b075 339 SMART SM00729 55 263 3.3E-34 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CXR48_RS09145 27ec7273be4dd4b22264563e9ae8b075 339 Gene3D G3DSA:3.20.20.70 14 324 3.4E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS09145 27ec7273be4dd4b22264563e9ae8b075 339 SMART SM00876 231 321 8.5E-32 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CXR48_RS09145 27ec7273be4dd4b22264563e9ae8b075 339 Pfam PF04055 Radical SAM superfamily 65 220 4.7E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS09145 27ec7273be4dd4b22264563e9ae8b075 339 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 231 320 1.5E-14 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CXR48_RS09145 27ec7273be4dd4b22264563e9ae8b075 339 SUPERFAMILY SSF102114 16 320 3.14E-70 T 29-03-2018 CXR48_RS09145 27ec7273be4dd4b22264563e9ae8b075 339 PIRSF PIRSF001619 1 328 2.6E-127 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CXR48_RS09145 27ec7273be4dd4b22264563e9ae8b075 339 Hamap MF_01694 Biotin synthase [bioB]. 15 322 40.677 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CXR48_RS14610 337a598919f31a7cf703ddf8d06a1b2c 130 SMART SM00316 6 77 1.0E-26 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS14610 337a598919f31a7cf703ddf8d06a1b2c 130 Pfam PF00575 S1 RNA binding domain 4 77 1.7E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS14610 337a598919f31a7cf703ddf8d06a1b2c 130 Gene3D G3DSA:2.40.50.140 8 107 3.9E-28 T 29-03-2018 CXR48_RS14610 337a598919f31a7cf703ddf8d06a1b2c 130 PRINTS PR00681 Ribosomal protein S1 signature 60 78 3.7E-11 T 29-03-2018 CXR48_RS14610 337a598919f31a7cf703ddf8d06a1b2c 130 PRINTS PR00681 Ribosomal protein S1 signature 21 40 3.7E-11 T 29-03-2018 CXR48_RS14610 337a598919f31a7cf703ddf8d06a1b2c 130 SUPERFAMILY SSF50249 5 87 2.33E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS14600 e2c46b5f933da3ddc61ce34b7f933f88 387 Gene3D G3DSA:3.40.50.1970 9 183 7.4E-53 T 29-03-2018 CXR48_RS14600 e2c46b5f933da3ddc61ce34b7f933f88 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CXR48_RS14600 e2c46b5f933da3ddc61ce34b7f933f88 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 368 9.9E-104 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CXR48_RS14600 e2c46b5f933da3ddc61ce34b7f933f88 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CXR48_RS14600 e2c46b5f933da3ddc61ce34b7f933f88 387 SUPERFAMILY SSF56796 1 385 1.44E-119 T 29-03-2018 CXR48_RS14600 e2c46b5f933da3ddc61ce34b7f933f88 387 Gene3D G3DSA:1.20.1090.10 184 387 8.8E-48 T 29-03-2018 CXR48_RS09190 8daaec6dc1e3ac01bdeba658798ba060 259 Gene3D G3DSA:1.10.12.10 217 259 2.0E-19 T 29-03-2018 IPR014748 Crontonase, C-terminal CXR48_RS09190 8daaec6dc1e3ac01bdeba658798ba060 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 258 6.1E-67 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CXR48_RS09190 8daaec6dc1e3ac01bdeba658798ba060 259 Gene3D G3DSA:3.90.226.10 5 216 4.3E-74 T 29-03-2018 CXR48_RS09190 8daaec6dc1e3ac01bdeba658798ba060 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CXR48_RS09190 8daaec6dc1e3ac01bdeba658798ba060 259 SUPERFAMILY SSF52096 3 258 1.91E-84 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS05010 1a93f0453184a1dd60443a29001929f8 145 PRINTS PR00332 Histidine triad family signature 8 24 8.5E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CXR48_RS05010 1a93f0453184a1dd60443a29001929f8 145 PRINTS PR00332 Histidine triad family signature 96 106 8.5E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CXR48_RS05010 1a93f0453184a1dd60443a29001929f8 145 PRINTS PR00332 Histidine triad family signature 29 47 8.5E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CXR48_RS05010 1a93f0453184a1dd60443a29001929f8 145 SUPERFAMILY SSF54197 5 141 6.81E-49 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CXR48_RS05010 1a93f0453184a1dd60443a29001929f8 145 ProSitePatterns PS00892 HIT domain signature. 89 107 - T 29-03-2018 IPR019808 Histidine triad, conserved site CXR48_RS05010 1a93f0453184a1dd60443a29001929f8 145 Pfam PF01230 HIT domain 16 109 3.2E-29 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CXR48_RS05010 1a93f0453184a1dd60443a29001929f8 145 Gene3D G3DSA:3.30.428.10 1 115 7.2E-36 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CXR48_RS05010 1a93f0453184a1dd60443a29001929f8 145 Gene3D G3DSA:1.20.5.1170 117 142 1.6E-13 T 29-03-2018 CXR48_RS03120 98dacac34b1ee667ad2891edb2c377cb 353 SMART SM00829 15 349 1.4E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS03120 98dacac34b1ee667ad2891edb2c377cb 353 Pfam PF00107 Zinc-binding dehydrogenase 183 311 7.2E-36 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS03120 98dacac34b1ee667ad2891edb2c377cb 353 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CXR48_RS03120 98dacac34b1ee667ad2891edb2c377cb 353 SUPERFAMILY SSF50129 8 180 1.52E-61 T 29-03-2018 IPR011032 GroES-like CXR48_RS03120 98dacac34b1ee667ad2891edb2c377cb 353 SUPERFAMILY SSF51735 147 315 1.63E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS03120 98dacac34b1ee667ad2891edb2c377cb 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 142 9.6E-35 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS03120 98dacac34b1ee667ad2891edb2c377cb 353 Gene3D G3DSA:3.90.180.10 9 167 2.3E-57 T 29-03-2018 CXR48_RS03120 98dacac34b1ee667ad2891edb2c377cb 353 Gene3D G3DSA:3.40.50.10730 168 347 3.5E-34 T 29-03-2018 CXR48_RS10565 cf6430932e7075c06e482c211743fada 202 TIGRFAM TIGR00648 recU: recombination protein U 30 196 7.2E-89 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CXR48_RS10565 cf6430932e7075c06e482c211743fada 202 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 202 98.705 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CXR48_RS10565 cf6430932e7075c06e482c211743fada 202 SUPERFAMILY SSF52980 34 197 7.78E-65 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CXR48_RS10565 cf6430932e7075c06e482c211743fada 202 Pfam PF03838 Recombination protein U 31 193 6.0E-64 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CXR48_RS10565 cf6430932e7075c06e482c211743fada 202 Gene3D G3DSA:3.40.1350.10 32 196 2.6E-59 T 29-03-2018 CXR48_RS10565 cf6430932e7075c06e482c211743fada 202 PIRSF PIRSF037785 22 202 2.6E-76 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CXR48_RS01910 7c5f0b21eb3308312b22aee5a4908cb2 249 SUPERFAMILY SSF52540 1 238 6.5E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01910 7c5f0b21eb3308312b22aee5a4908cb2 249 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS01910 7c5f0b21eb3308312b22aee5a4908cb2 249 Pfam PF00005 ABC transporter 17 168 1.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS01910 7c5f0b21eb3308312b22aee5a4908cb2 249 Gene3D G3DSA:3.40.50.300 1 248 3.3E-76 T 29-03-2018 CXR48_RS01910 7c5f0b21eb3308312b22aee5a4908cb2 249 PIRSF PIRSF039085 1 244 4.6E-103 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CXR48_RS01910 7c5f0b21eb3308312b22aee5a4908cb2 249 SMART SM00382 26 216 2.2E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS02370 9cfc58d7df9c9f6f19b411d867cab52b 297 Gene3D G3DSA:3.30.70.1350 207 289 2.9E-18 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CXR48_RS02370 9cfc58d7df9c9f6f19b411d867cab52b 297 Pfam PF01545 Cation efflux family 16 207 1.2E-48 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CXR48_RS02370 9cfc58d7df9c9f6f19b411d867cab52b 297 SUPERFAMILY SSF160240 214 287 2.35E-18 T 29-03-2018 CXR48_RS02370 9cfc58d7df9c9f6f19b411d867cab52b 297 SUPERFAMILY SSF161111 8 209 5.62E-53 T 29-03-2018 CXR48_RS02370 9cfc58d7df9c9f6f19b411d867cab52b 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 216 288 1.5E-18 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CXR48_RS02370 9cfc58d7df9c9f6f19b411d867cab52b 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 288 1.3E-70 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CXR48_RS02370 9cfc58d7df9c9f6f19b411d867cab52b 297 Gene3D G3DSA:1.20.1510.10 12 206 4.4E-40 T 29-03-2018 CXR48_RS09010 a96c01c79e246477e2d23799e39e253b 318 SUPERFAMILY SSF53613 5 310 1.56E-81 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS09010 a96c01c79e246477e2d23799e39e253b 318 Gene3D G3DSA:3.40.1190.20 5 318 1.6E-67 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS09010 a96c01c79e246477e2d23799e39e253b 318 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CXR48_RS09010 a96c01c79e246477e2d23799e39e253b 318 Pfam PF00294 pfkB family carbohydrate kinase 7 301 1.7E-48 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CXR48_RS08370 0b5ff8d8b374c13b48cc9bbbed3cc2ca 555 Pfam PF00753 Metallo-beta-lactamase superfamily 20 167 3.5E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS08370 0b5ff8d8b374c13b48cc9bbbed3cc2ca 555 SMART SM00849 21 216 6.3E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS08370 0b5ff8d8b374c13b48cc9bbbed3cc2ca 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 362 407 1.3E-8 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CXR48_RS08370 0b5ff8d8b374c13b48cc9bbbed3cc2ca 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 45.088 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CXR48_RS08370 0b5ff8d8b374c13b48cc9bbbed3cc2ca 555 Gene3D G3DSA:3.60.15.10 1 448 6.4E-57 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS08370 0b5ff8d8b374c13b48cc9bbbed3cc2ca 555 PIRSF PIRSF004803 1 555 5.3E-228 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CXR48_RS08370 0b5ff8d8b374c13b48cc9bbbed3cc2ca 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 9.3E-224 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CXR48_RS08370 0b5ff8d8b374c13b48cc9bbbed3cc2ca 555 SUPERFAMILY SSF56281 10 424 1.07E-78 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 ProSitePatterns PS00785 5'-nucleotidase signature 1. 45 57 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 PRINTS PR01607 Apyrase family signature 668 686 1.6E-42 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 PRINTS PR01607 Apyrase family signature 1114 1133 1.6E-42 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 PRINTS PR01607 Apyrase family signature 882 905 1.6E-42 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 PRINTS PR01607 Apyrase family signature 913 933 1.6E-42 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 PRINTS PR01607 Apyrase family signature 863 880 1.6E-42 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 PRINTS PR01607 Apyrase family signature 1036 1059 1.6E-42 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 SUPERFAMILY SSF56300 41 373 1.34E-83 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 Gene3D G3DSA:3.90.780.10 992 1177 8.9E-64 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1392 1423 0.0034 T 29-03-2018 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 ProSitePatterns PS00785 5'-nucleotidase signature 1. 670 682 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 Pfam PF00149 Calcineurin-like phosphoesterase 46 284 2.7E-15 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 Pfam PF00149 Calcineurin-like phosphoesterase 670 899 1.8E-15 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 SUPERFAMILY SSF55816 375 611 1.7E-45 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 Gene3D G3DSA:3.60.21.10 34 365 2.4E-85 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 Gene3D G3DSA:3.60.21.10 659 991 1.9E-78 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 Gene3D G3DSA:3.90.780.10 366 618 1.1E-56 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 SUPERFAMILY SSF55816 976 1176 2.35E-60 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 SUPERFAMILY SSF56300 664 975 7.75E-77 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 ProSitePatterns PS00786 5'-nucleotidase signature 2. 134 145 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 Pfam PF02872 5'-nucleotidase, C-terminal domain 375 573 1.1E-24 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03840 e4136328d0690510d23058c7bb3d895d 1430 Pfam PF02872 5'-nucleotidase, C-terminal domain 978 1140 1.2E-48 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 SUPERFAMILY SSF48452 699 805 4.09E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 SUPERFAMILY SSF52540 167 398 5.48E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 Pfam PF00931 NB-ARC domain 184 393 2.7E-8 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 Gene3D G3DSA:1.25.40.10 598 709 9.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 Gene3D G3DSA:3.40.50.300 154 318 4.3E-14 T 29-03-2018 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 Gene3D G3DSA:1.25.40.10 710 749 5.4E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 Pfam PF13181 Tetratricopeptide repeat 737 761 6.2E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 SMART SM00382 192 382 5.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 SMART SM00028 697 730 450.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 SMART SM00028 775 808 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 SMART SM00028 736 768 12.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 SUPERFAMILY SSF48452 622 723 4.64E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03115 d4567d2f28092d7822b49748aadbde5e 833 Gene3D G3DSA:1.25.40.10 750 807 3.7E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03730 96d99c8387b63c182de3d340f587ade3 432 Pfam PF03600 Citrate transporter 13 377 2.7E-42 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CXR48_RS03730 96d99c8387b63c182de3d340f587ade3 432 TIGRFAM TIGR00784 citMHS: citrate transporter 2 431 1.2E-229 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 CXR48_RS00890 6c3f34312d6fe2e8c197f47152a6c3d4 289 Pfam PF00005 ABC transporter 25 174 2.8E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS00890 6c3f34312d6fe2e8c197f47152a6c3d4 289 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS00890 6c3f34312d6fe2e8c197f47152a6c3d4 289 SMART SM00382 32 223 9.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS00890 6c3f34312d6fe2e8c197f47152a6c3d4 289 SUPERFAMILY SSF52540 3 236 1.65E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00890 6c3f34312d6fe2e8c197f47152a6c3d4 289 Gene3D G3DSA:3.40.50.300 1 282 1.1E-64 T 29-03-2018 CXR48_RS00890 6c3f34312d6fe2e8c197f47152a6c3d4 289 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 1.9E-120 T 29-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CXR48_RS13895 d7f39b9d4805b269daa48d70acfbd2e1 183 Gene3D G3DSA:3.90.1140.10 7 183 3.3E-34 T 29-03-2018 CXR48_RS13895 d7f39b9d4805b269daa48d70acfbd2e1 183 SUPERFAMILY SSF55144 6 182 2.27E-41 T 29-03-2018 IPR009097 Cyclic phosphodiesterase CXR48_RS13895 d7f39b9d4805b269daa48d70acfbd2e1 183 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 7 182 1.3E-46 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CXR48_RS13895 d7f39b9d4805b269daa48d70acfbd2e1 183 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 6 182 21.499 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CXR48_RS13895 d7f39b9d4805b269daa48d70acfbd2e1 183 Pfam PF13563 2'-5' RNA ligase superfamily 15 136 1.4E-17 T 29-03-2018 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 Gene3D G3DSA:3.40.50.2300 1 125 1.0E-35 T 29-03-2018 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 SUPERFAMILY SSF52172 1 130 7.83E-36 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 SUPERFAMILY SSF46894 138 207 9.18E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 Pfam PF00072 Response regulator receiver domain 4 112 2.1E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 SMART SM00421 144 201 5.8E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 4.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 4.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 4.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 9.2E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 SMART SM00448 2 114 7.7E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS02800 0223a17504b2a12e3b37075359e7f76c 211 Gene3D G3DSA:1.10.10.10 126 211 5.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05725 3efe2eff3edf2223470e3fba4c0cd66d 235 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 215 4.2E-88 T 29-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 CXR48_RS05725 3efe2eff3edf2223470e3fba4c0cd66d 235 SUPERFAMILY SSF48613 3 220 2.82E-70 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CXR48_RS05725 3efe2eff3edf2223470e3fba4c0cd66d 235 Gene3D G3DSA:1.20.910.10 1 222 3.6E-53 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CXR48_RS05725 3efe2eff3edf2223470e3fba4c0cd66d 235 Pfam PF03070 TENA/THI-4/PQQC family 9 214 3.3E-61 T 29-03-2018 IPR004305 Thiaminase-2/PQQC CXR48_RS07855 da93006837385790f035b7a07240a5f5 253 Pfam PF13672 Protein phosphatase 2C 13 230 8.4E-25 T 29-03-2018 CXR48_RS07855 da93006837385790f035b7a07240a5f5 253 SMART SM00331 7 242 1.3E-59 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS07855 da93006837385790f035b7a07240a5f5 253 SMART SM00332 1 240 2.6E-35 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS07855 da93006837385790f035b7a07240a5f5 253 Gene3D G3DSA:3.60.40.10 2 242 4.5E-51 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS07855 da93006837385790f035b7a07240a5f5 253 SUPERFAMILY SSF81606 5 242 1.01E-69 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS13220 b092d1f4376b05f730df284a51d1ba29 313 Gene3D G3DSA:3.30.420.10 94 312 3.7E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS13220 b092d1f4376b05f730df284a51d1ba29 313 PIRSF PIRSF037748 1 309 1.6E-118 T 29-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CXR48_RS13220 b092d1f4376b05f730df284a51d1ba29 313 Pfam PF11858 Domain of unknown function (DUF3378) 3 76 3.2E-27 T 29-03-2018 IPR024568 Ribonuclease HIII, N-terminal CXR48_RS13220 b092d1f4376b05f730df284a51d1ba29 313 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 5 300 2.1E-124 T 29-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CXR48_RS13220 b092d1f4376b05f730df284a51d1ba29 313 SUPERFAMILY SSF53098 95 307 6.37E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS13220 b092d1f4376b05f730df284a51d1ba29 313 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 308 34.634 T 29-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CXR48_RS13220 b092d1f4376b05f730df284a51d1ba29 313 Pfam PF01351 Ribonuclease HII 97 301 5.0E-56 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.7E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 SUPERFAMILY SSF46785 1 84 9.82E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 Gene3D G3DSA:3.40.190.10 89 180 2.5E-21 T 29-03-2018 CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 Gene3D G3DSA:1.10.10.10 1 83 6.5E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 Gene3D G3DSA:3.40.190.10 181 267 2.1E-23 T 29-03-2018 CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 SUPERFAMILY SSF53850 88 296 1.33E-40 T 29-03-2018 CXR48_RS09335 019b2e791c8a0509b5a0530d98dbe05f 300 Pfam PF03466 LysR substrate binding domain 89 291 3.7E-46 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS05580 628d8796931ab70d3d2346619c2246be 329 Gene3D G3DSA:3.40.50.300 6 329 8.7E-85 T 29-03-2018 CXR48_RS05580 628d8796931ab70d3d2346619c2246be 329 SMART SM00382 45 238 4.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS05580 628d8796931ab70d3d2346619c2246be 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 307 7.0E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS05580 628d8796931ab70d3d2346619c2246be 329 SUPERFAMILY SSF52540 9 260 9.2E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05580 628d8796931ab70d3d2346619c2246be 329 Pfam PF00005 ABC transporter 37 188 1.1E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS05580 628d8796931ab70d3d2346619c2246be 329 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS05580 628d8796931ab70d3d2346619c2246be 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 327 2.5E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 SMART SM00612 108 159 7.8E-5 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 SMART SM00612 207 258 9.6E-4 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 SMART SM00612 259 306 9.7E-5 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 SMART SM00612 160 206 17.0 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 SMART SM00612 61 107 1.3E-7 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 Gene3D G3DSA:2.120.10.80 20 156 3.8E-32 T 29-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 Pfam PF01344 Kelch motif 197 244 1.4E-8 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 Pfam PF01344 Kelch motif 49 94 8.8E-10 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 Pfam PF01344 Kelch motif 96 144 6.3E-13 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 Pfam PF13964 Kelch motif 250 296 1.5E-7 T 29-03-2018 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 Pfam PF13964 Kelch motif 151 194 4.8E-6 T 29-03-2018 CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 SUPERFAMILY SSF50965 38 319 8.11E-57 T 29-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller CXR48_RS10195 1dad87d0a9b21e98c13b9d2555f85304 440 Gene3D G3DSA:2.120.10.80 157 364 5.8E-37 T 29-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 CXR48_RS01000 df2a84fc2b737367c8ec2b662200596e 250 Gene3D G3DSA:3.40.50.1820 6 250 1.1E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS01000 df2a84fc2b737367c8ec2b662200596e 250 SUPERFAMILY SSF53474 13 244 3.5E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS01000 df2a84fc2b737367c8ec2b662200596e 250 Pfam PF00756 Putative esterase 15 241 1.7E-24 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CXR48_RS14485 e3585f5610a791d5586354351606ced0 174 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 7 171 5.8E-49 T 29-03-2018 IPR006286 Peptidase C56, PfpI CXR48_RS14485 e3585f5610a791d5586354351606ced0 174 Pfam PF01965 DJ-1/PfpI family 6 168 1.1E-45 T 29-03-2018 IPR002818 DJ-1/PfpI CXR48_RS14485 e3585f5610a791d5586354351606ced0 174 SUPERFAMILY SSF52317 5 173 1.41E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS14485 e3585f5610a791d5586354351606ced0 174 Gene3D G3DSA:3.40.50.880 1 174 4.6E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 Gene3D G3DSA:2.40.50.140 179 260 1.1E-27 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 Gene3D G3DSA:2.40.50.140 5 90 6.3E-14 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 Gene3D G3DSA:2.40.50.140 91 175 4.8E-12 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 SUPERFAMILY SSF50249 256 345 1.44E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 SUPERFAMILY SSF50249 10 109 2.33E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 Gene3D G3DSA:2.40.50.140 273 368 6.2E-26 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 SMART SM00316 186 256 1.6E-28 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 SMART SM00316 14 84 4.2E-14 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 SMART SM00316 271 342 2.9E-26 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 SMART SM00316 100 167 1.1E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 SUPERFAMILY SSF50249 185 273 4.53E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 SUPERFAMILY SSF50249 88 170 2.54E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 325 343 1.9E-49 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 105 121 1.9E-49 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 286 305 1.9E-49 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 151 171 1.9E-49 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 208 229 1.9E-49 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 81 100 1.9E-49 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 122 139 1.9E-49 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 16 34 1.9E-49 T 29-03-2018 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 Pfam PF00575 S1 RNA binding domain 100 167 1.0E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 Pfam PF00575 S1 RNA binding domain 269 342 6.0E-24 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 Pfam PF00575 S1 RNA binding domain 13 83 2.7E-16 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS10855 d537cb9415a903d13423a96fa1358b34 382 Pfam PF00575 S1 RNA binding domain 185 256 2.3E-26 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 Gene3D G3DSA:3.40.50.670 403 635 3.6E-106 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 638 98.548 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 Gene3D G3DSA:3.30.565.10 20 223 1.2E-75 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 SUPERFAMILY SSF55874 8 220 1.09E-73 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 176 1.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 Pfam PF01751 Toprim domain 423 534 5.4E-19 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 SUPERFAMILY SSF54211 225 395 5.12E-64 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR00418 DNA topoisomerase II family signature 115 129 1.6E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR00418 DNA topoisomerase II family signature 490 506 1.6E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR00418 DNA topoisomerase II family signature 528 540 1.6E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR00418 DNA topoisomerase II family signature 508 525 1.6E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR00418 DNA topoisomerase II family signature 37 52 1.6E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR00418 DNA topoisomerase II family signature 424 438 1.6E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR00418 DNA topoisomerase II family signature 272 285 1.6E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR00418 DNA topoisomerase II family signature 72 85 1.6E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR00418 DNA topoisomerase II family signature 570 586 1.6E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 638 0.0 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 568 627 4.1E-30 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 SMART SM00433 37 631 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 198 211 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 607 623 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 8 18 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 474 483 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 224 246 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 183 198 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 316 332 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 591 603 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 364 378 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 PRINTS PR01159 DNA gyrase subunit B signature 378 398 1.8E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 SMART SM00387 33 177 1.4E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 SUPERFAMILY SSF56719 398 629 6.8E-93 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 Pfam PF00204 DNA gyrase B 225 394 4.3E-65 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00030 da905b6af908f79b6ad8d63423b8e249 638 Gene3D G3DSA:3.30.230.10 224 396 1.0E-67 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS09770 cae333afe8594b81382b157952ed6f1a 74 Gene3D G3DSA:1.10.150.260 3 69 3.5E-27 T 29-03-2018 IPR023089 YozE SAM-like domain CXR48_RS09770 cae333afe8594b81382b157952ed6f1a 74 Hamap MF_01538 UPF0346 protein . 1 70 22.99 T 29-03-2018 IPR010673 Protein of unknown function UPF0346 CXR48_RS09770 cae333afe8594b81382b157952ed6f1a 74 Pfam PF06855 YozE SAM-like fold 3 68 2.6E-27 T 29-03-2018 IPR023089 YozE SAM-like domain CXR48_RS09770 cae333afe8594b81382b157952ed6f1a 74 SUPERFAMILY SSF140652 1 71 1.57E-29 T 29-03-2018 IPR023089 YozE SAM-like domain CXR48_RS09770 cae333afe8594b81382b157952ed6f1a 74 PIRSF PIRSF037262 1 72 3.8E-35 T 29-03-2018 IPR010673 Protein of unknown function UPF0346 CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 SMART SM00448 175 297 3.4E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 Gene3D G3DSA:2.30.30.40 98 142 2.2E-12 T 29-03-2018 CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 Gene3D G3DSA:3.40.50.2300 167 302 3.6E-23 T 29-03-2018 CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 Pfam PF00072 Response regulator receiver domain 178 297 2.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 Gene3D G3DSA:2.40.50.180 35 97 2.0E-16 T 29-03-2018 CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 SUPERFAMILY SSF50341 8 153 2.35E-32 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 PIRSF PIRSF002867 2 303 6.5E-98 T 29-03-2018 IPR024181 Chemotaxis response regulator CheV CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 SMART SM00260 14 149 1.1E-35 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 Pfam PF01584 CheW-like domain 19 152 6.6E-33 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CXR48_RS06930 cb6f5e50177505c93987eee81b5e2084 303 SUPERFAMILY SSF52172 174 299 2.13E-24 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS18680 f3345728d44a830bf6f2e6afe55e8b32 229 Gene3D G3DSA:1.10.10.10 120 229 7.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18680 f3345728d44a830bf6f2e6afe55e8b32 229 SUPERFAMILY SSF52172 3 177 6.4E-36 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS18680 f3345728d44a830bf6f2e6afe55e8b32 229 SMART SM00448 2 112 2.1E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS18680 f3345728d44a830bf6f2e6afe55e8b32 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 1.5E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS18680 f3345728d44a830bf6f2e6afe55e8b32 229 Pfam PF00072 Response regulator receiver domain 4 112 3.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS18680 f3345728d44a830bf6f2e6afe55e8b32 229 SMART SM00862 150 225 1.9E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS18680 f3345728d44a830bf6f2e6afe55e8b32 229 Gene3D G3DSA:3.40.50.2300 1 119 4.7E-32 T 29-03-2018 CXR48_RS15825 394e04fa36f8c48447673c47997b722e 156 SUPERFAMILY SSF74982 4 132 2.22E-54 T 29-03-2018 IPR023620 Small protein B CXR48_RS15825 394e04fa36f8c48447673c47997b722e 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 11 132 1.0E-64 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CXR48_RS15825 394e04fa36f8c48447673c47997b722e 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 149 7.3E-61 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CXR48_RS15825 394e04fa36f8c48447673c47997b722e 156 Pfam PF01668 SmpB protein 10 150 2.5E-64 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CXR48_RS15825 394e04fa36f8c48447673c47997b722e 156 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site CXR48_RS15825 394e04fa36f8c48447673c47997b722e 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 79.519 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CXR48_RS15825 394e04fa36f8c48447673c47997b722e 156 Gene3D G3DSA:2.40.280.10 9 127 1.8E-53 T 29-03-2018 IPR023620 Small protein B CXR48_RS02430 71eaed4225533056c7d2b4a3109e1240 116 PIRSF PIRSF033490 1 113 2.6E-39 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CXR48_RS02430 71eaed4225533056c7d2b4a3109e1240 116 Gene3D G3DSA:2.30.30.110 1 116 1.8E-38 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CXR48_RS02430 71eaed4225533056c7d2b4a3109e1240 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 4.7E-33 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CXR48_RS02430 71eaed4225533056c7d2b4a3109e1240 116 SUPERFAMILY SSF50118 2 113 2.78E-41 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 Pfam PF00667 FAD binding domain 230 425 3.6E-33 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PIRSF PIRSF000207 1 602 7.4E-272 T 29-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 Pfam PF00258 Flavodoxin 67 198 2.9E-34 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 389 396 7.7E-29 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 551 559 7.7E-29 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 484 493 7.7E-29 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 528 544 7.7E-29 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 268 278 7.7E-29 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 497 508 7.7E-29 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 459 478 7.7E-29 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 Pfam PF00175 Oxidoreductase NAD-binding domain 460 566 3.2E-18 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 6 602 2.4E-272 T 29-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 Gene3D G3DSA:3.40.50.360 38 221 6.0E-44 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 SUPERFAMILY SSF63380 227 448 2.49E-64 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00369 Flavodoxin signature 66 79 7.3E-16 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00369 Flavodoxin signature 114 125 7.3E-16 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00369 Flavodoxin signature 146 156 7.3E-16 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 PRINTS PR00369 Flavodoxin signature 170 189 7.3E-16 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 Gene3D G3DSA:3.40.50.80 448 600 2.3E-38 T 29-03-2018 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 Gene3D G3DSA:2.40.30.10 222 442 2.2E-51 T 29-03-2018 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 SUPERFAMILY SSF52343 447 602 7.33E-53 T 29-03-2018 CXR48_RS15700 e41985e817c0c6f0e72b3a4f37df0dbf 602 SUPERFAMILY SSF52218 63 206 1.16E-50 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS12280 7494fa4bae8b51008ec38644611754dc 340 SUPERFAMILY SSF48019 217 336 4.59E-27 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CXR48_RS12280 7494fa4bae8b51008ec38644611754dc 340 Pfam PF06144 DNA polymerase III, delta subunit 18 193 6.8E-51 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CXR48_RS12280 7494fa4bae8b51008ec38644611754dc 340 Gene3D G3DSA:1.20.272.10 226 340 2.2E-37 T 29-03-2018 CXR48_RS12280 7494fa4bae8b51008ec38644611754dc 340 SUPERFAMILY SSF52540 4 214 7.44E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12280 7494fa4bae8b51008ec38644611754dc 340 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 15 336 1.8E-88 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CXR48_RS12280 7494fa4bae8b51008ec38644611754dc 340 Gene3D G3DSA:3.40.50.300 4 144 2.4E-30 T 29-03-2018 CXR48_RS12280 7494fa4bae8b51008ec38644611754dc 340 Gene3D G3DSA:1.10.8.60 147 225 7.1E-22 T 29-03-2018 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 Gene3D G3DSA:3.40.50.10860 11 139 4.3E-46 T 29-03-2018 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 SUPERFAMILY SSF53223 1 121 4.22E-40 T 29-03-2018 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 SUPERFAMILY SSF51735 122 280 2.49E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 Gene3D G3DSA:3.40.50.720 140 263 1.0E-41 T 29-03-2018 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.3E-39 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.5E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.5E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.5E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.5E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.5E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.5E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.5E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 40.276 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS11675 ea7ce85119adbbfa89b5dce0a2aa487d 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 2.0E-75 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CXR48_RS07595 f153a1bb8585903e311caa2d2585294e 303 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 299 6.4E-29 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS07595 f153a1bb8585903e311caa2d2585294e 303 SUPERFAMILY SSF56194 197 300 3.92E-36 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS07595 f153a1bb8585903e311caa2d2585294e 303 Pfam PF01565 FAD binding domain 35 164 9.8E-26 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CXR48_RS07595 f153a1bb8585903e311caa2d2585294e 303 Gene3D G3DSA:3.90.78.10 205 299 3.7E-28 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS07595 f153a1bb8585903e311caa2d2585294e 303 Gene3D G3DSA:3.30.465.10 89 204 8.1E-35 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS07595 f153a1bb8585903e311caa2d2585294e 303 SUPERFAMILY SSF56176 14 193 3.31E-44 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS07595 f153a1bb8585903e311caa2d2585294e 303 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 300 1.9E-113 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS07595 f153a1bb8585903e311caa2d2585294e 303 Gene3D G3DSA:3.30.43.10 14 88 1.2E-24 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CXR48_RS07595 f153a1bb8585903e311caa2d2585294e 303 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 303 91.597 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS10510 383ce9816a707b5eddc8dd67d75edf19 78 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 7 77 2.0E-27 T 29-03-2018 IPR020108 Spore coat protein CotD CXR48_RS10510 383ce9816a707b5eddc8dd67d75edf19 78 Pfam PF11122 Inner spore coat protein D 13 74 1.3E-15 T 29-03-2018 IPR020108 Spore coat protein CotD CXR48_RS02470 37f62cc2c7cb959fd61f806121ba2955 200 SMART SM00332 6 196 0.0017 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS02470 37f62cc2c7cb959fd61f806121ba2955 200 SUPERFAMILY SSF81606 15 195 7.46E-13 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS02470 37f62cc2c7cb959fd61f806121ba2955 200 SMART SM00331 9 198 9.0E-46 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS02470 37f62cc2c7cb959fd61f806121ba2955 200 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 36 158 1.5E-13 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS02470 37f62cc2c7cb959fd61f806121ba2955 200 Gene3D G3DSA:3.60.40.10 1 198 1.2E-20 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 SUPERFAMILY SSF55785 246 356 1.03E-8 T 29-03-2018 IPR000014 PAS domain CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 SUPERFAMILY SSF55874 420 587 5.5E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 Gene3D G3DSA:3.30.565.10 426 589 7.5E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 SMART SM00388 364 431 4.5E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 587 7.6E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 SUPERFAMILY SSF47384 348 432 3.73E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 SMART SM00091 253 320 8.7E-7 T 29-03-2018 IPR000014 PAS domain CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 Pfam PF00989 PAS fold 253 355 5.9E-11 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 431 1.4E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 SMART SM00387 477 589 1.5E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 Gene3D G3DSA:3.30.450.20 250 369 7.3E-13 T 29-03-2018 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 SMART SM00304 194 246 2.1E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 SUPERFAMILY SSF158472 195 242 8.89E-10 T 29-03-2018 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 Gene3D G3DSA:1.10.287.130 370 425 2.8E-18 T 29-03-2018 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 Gene3D G3DSA:3.30.450.20 32 168 3.3E-8 T 29-03-2018 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 8.2E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 8.2E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 567 8.2E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 586 8.2E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS10955 c38dba57e0f09da1c4621be6289dd238 593 Pfam PF00672 HAMP domain 195 241 1.6E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 327 2.9E-60 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 341 37.722 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 SMART SM00859 6 121 2.9E-41 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 SUPERFAMILY SSF55347 129 328 1.57E-74 T 29-03-2018 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 342 2.1E-164 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 237 251 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 120 1.1E-33 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 SUPERFAMILY SSF51735 5 157 3.96E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 Gene3D G3DSA:3.30.360.10 141 324 9.6E-72 T 29-03-2018 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 PIRSF PIRSF000148 4 346 4.4E-129 T 29-03-2018 CXR48_RS08355 9f08fcdfb7d784a3d45a5b2ebdff6808 346 Gene3D G3DSA:3.40.50.720 2 140 3.3E-34 T 29-03-2018 CXR48_RS01915 e7f3d775bbc7ccf8a5f63f7a62e9cce4 383 SUPERFAMILY SSF53187 4 196 5.74E-86 T 29-03-2018 CXR48_RS01915 e7f3d775bbc7ccf8a5f63f7a62e9cce4 383 SUPERFAMILY SSF53187 297 380 5.74E-86 T 29-03-2018 CXR48_RS01915 e7f3d775bbc7ccf8a5f63f7a62e9cce4 383 Pfam PF01546 Peptidase family M20/M25/M40 72 376 1.9E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS01915 e7f3d775bbc7ccf8a5f63f7a62e9cce4 383 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 13 367 1.4E-124 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CXR48_RS01915 e7f3d775bbc7ccf8a5f63f7a62e9cce4 383 SUPERFAMILY SSF55031 182 295 1.57E-31 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS01915 e7f3d775bbc7ccf8a5f63f7a62e9cce4 383 Pfam PF07687 Peptidase dimerisation domain 184 277 5.7E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS01915 e7f3d775bbc7ccf8a5f63f7a62e9cce4 383 PIRSF PIRSF005962 1 383 1.7E-127 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CXR48_RS01915 e7f3d775bbc7ccf8a5f63f7a62e9cce4 383 Gene3D G3DSA:3.40.630.10 243 383 1.6E-22 T 29-03-2018 CXR48_RS01915 e7f3d775bbc7ccf8a5f63f7a62e9cce4 383 Gene3D G3DSA:3.40.630.10 1 237 2.2E-51 T 29-03-2018 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 Gene3D G3DSA:3.30.360.10 190 489 4.3E-123 T 29-03-2018 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 8 488 3.2E-209 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 12 188 1.5E-61 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 PIRSF PIRSF000110 1 489 1.1E-187 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 191 486 8.0E-115 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 178 184 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 SUPERFAMILY SSF51735 7 185 5.51E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 Gene3D G3DSA:3.40.50.720 6 189 2.5E-68 T 29-03-2018 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 8 488 90.972 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 220 237 2.5E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 144 157 2.5E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 329 355 2.5E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 238 254 2.5E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 168 196 2.5E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CXR48_RS11435 ca2313e56935c7cdb44543a2763df0f0 489 SUPERFAMILY SSF55347 183 487 2.62E-116 T 29-03-2018 CXR48_RS16860 44e9b02b15b68f289125b7fdfca99ec6 368 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 361 7.0E-69 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CXR48_RS16860 44e9b02b15b68f289125b7fdfca99ec6 368 Pfam PF03845 Spore germination protein 7 330 9.8E-92 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CXR48_RS16860 44e9b02b15b68f289125b7fdfca99ec6 368 PIRSF PIRSF006060 1 292 6.6E-14 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS16860 44e9b02b15b68f289125b7fdfca99ec6 368 PIRSF PIRSF006060 305 367 2.1 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 Gene3D G3DSA:3.10.450.40 140 218 2.2E-4 T 29-03-2018 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 SUPERFAMILY SSF55486 222 521 2.2E-101 T 29-03-2018 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 225 372 2.0E-51 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 Pfam PF03413 Peptidase propeptide and YPEB domain 139 215 3.2E-11 T 29-03-2018 IPR025711 PepSY domain CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 375 520 3.3E-48 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 Gene3D G3DSA:3.10.170.10 224 376 5.6E-53 T 29-03-2018 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 78 126 4.9E-14 T 29-03-2018 IPR011096 FTP domain CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 448 464 1.8E-28 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 363 379 1.8E-28 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 384 395 1.8E-28 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 327 347 1.8E-28 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CXR48_RS07335 ac96e91169052f543b5b3d7adf55f356 521 Gene3D G3DSA:1.10.390.10 377 521 1.2E-50 T 29-03-2018 CXR48_RS00880 bb141308cb8a2d6af3a1fd029d1e177b 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 120 2.9E-50 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00880 bb141308cb8a2d6af3a1fd029d1e177b 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 29.088 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00880 bb141308cb8a2d6af3a1fd029d1e177b 120 Gene3D G3DSA:3.90.1030.10 1 120 3.7E-49 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00880 bb141308cb8a2d6af3a1fd029d1e177b 120 Pfam PF01196 Ribosomal protein L17 16 120 5.1E-40 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00880 bb141308cb8a2d6af3a1fd029d1e177b 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00880 bb141308cb8a2d6af3a1fd029d1e177b 120 SUPERFAMILY SSF64263 2 120 4.19E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS05665 2ad0dddbeaf6df4f3d7082f41e90ca7b 609 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 13 601 6.7E-231 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CXR48_RS05665 2ad0dddbeaf6df4f3d7082f41e90ca7b 609 Pfam PF01432 Peptidase family M3 211 590 2.9E-87 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CXR48_RS05665 2ad0dddbeaf6df4f3d7082f41e90ca7b 609 SUPERFAMILY SSF55486 10 587 5.46E-144 T 29-03-2018 CXR48_RS05665 2ad0dddbeaf6df4f3d7082f41e90ca7b 609 Pfam PF08439 Oligopeptidase F 120 189 6.4E-24 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CXR48_RS05665 2ad0dddbeaf6df4f3d7082f41e90ca7b 609 Gene3D G3DSA:1.10.1370.10 84 603 4.1E-50 T 29-03-2018 CXR48_RS04005 5b328ac4c09ba2164c6975172185f361 528 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 408 512 3.3E-28 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS04005 5b328ac4c09ba2164c6975172185f361 528 Pfam PF00367 phosphotransferase system, EIIB 457 486 7.8E-16 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS04005 5b328ac4c09ba2164c6975172185f361 528 TIGRFAM TIGR02005 PTS-IIBC-alpha: PTS system, alpha-glucoside-specific IIBC component 2 524 1.2E-264 T 29-03-2018 IPR010975 Phosphotransferase system, alpha-glucoside-specific IIBC component GO:0008982|GO:0009401 CXR48_RS04005 5b328ac4c09ba2164c6975172185f361 528 Gene3D G3DSA:3.30.1360.60 450 526 4.8E-25 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS04005 5b328ac4c09ba2164c6975172185f361 528 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 59 357 3.3E-91 T 29-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS04005 5b328ac4c09ba2164c6975172185f361 528 Pfam PF02378 Phosphotransferase system, EIIC 10 345 2.3E-74 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS04005 5b328ac4c09ba2164c6975172185f361 528 SUPERFAMILY SSF55604 452 526 4.58E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS04005 5b328ac4c09ba2164c6975172185f361 528 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 465 482 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 SUPERFAMILY SSF49464 837 904 6.67E-8 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 SUPERFAMILY SSF49464 910 1001 1.61E-12 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Gene3D G3DSA:3.40.50.200 187 521 1.7E-76 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Gene3D G3DSA:3.30.70.80 61 182 6.4E-9 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Pfam PF13715 CarboxypepD_reg-like domain 834 905 1.1E-8 T 29-03-2018 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Pfam PF13715 CarboxypepD_reg-like domain 911 985 1.3E-10 T 29-03-2018 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 SUPERFAMILY SSF49899 638 791 5.06E-8 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Gene3D G3DSA:2.60.40.1120 910 1010 1.2E-11 T 29-03-2018 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 PRINTS PR00723 Subtilisin serine protease family (S8) signature 451 467 3.5E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 PRINTS PR00723 Subtilisin serine protease family (S8) signature 272 285 3.5E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 PRINTS PR00723 Subtilisin serine protease family (S8) signature 220 239 3.5E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Gene3D G3DSA:2.60.40.1120 832 906 3.1E-8 T 29-03-2018 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Pfam PF05547 Immune inhibitor A peptidase M6 699 790 1.5E-10 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Gene3D G3DSA:2.60.40.10 1152 1238 3.3E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Gene3D G3DSA:2.60.40.10 1240 1326 3.3E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Gene3D G3DSA:2.60.40.10 534 628 0.27 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 PIRSF PIRSF015477 1 1431 0.0 T 29-03-2018 IPR012103 Peptidase S8A, bacillopeptidase F CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Gene3D G3DSA:2.60.120.260 636 792 1.8E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Pfam PF05922 Peptidase inhibitor I9 68 177 4.3E-8 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 452 462 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 SUPERFAMILY SSF52743 164 517 9.56E-71 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 Pfam PF00082 Subtilase family 220 506 4.1E-50 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS07615 066a39b65bc4245e34471aa2c361e77c 1431 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 276 286 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CXR48_RS19030 46c4ea798b401bea7b36c7c9b3fbaed2 235 SUPERFAMILY SSF52172 2 125 4.98E-44 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS19030 46c4ea798b401bea7b36c7c9b3fbaed2 235 Pfam PF00072 Response regulator receiver domain 5 114 1.5E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS19030 46c4ea798b401bea7b36c7c9b3fbaed2 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 7.5E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS19030 46c4ea798b401bea7b36c7c9b3fbaed2 235 SMART SM00448 3 113 4.2E-48 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS19030 46c4ea798b401bea7b36c7c9b3fbaed2 235 SUPERFAMILY SSF46894 130 230 2.13E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS19030 46c4ea798b401bea7b36c7c9b3fbaed2 235 SMART SM00862 153 229 5.5E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS19030 46c4ea798b401bea7b36c7c9b3fbaed2 235 Gene3D G3DSA:3.40.50.2300 1 126 6.5E-40 T 29-03-2018 CXR48_RS19030 46c4ea798b401bea7b36c7c9b3fbaed2 235 Gene3D G3DSA:1.10.10.10 127 235 1.5E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Gene3D G3DSA:3.40.50.1780 197 227 0.0014 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Gene3D G3DSA:3.30.70.20 148 196 1.5E-8 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 6 77 4.2E-16 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 SMART SM00929 86 127 2.1E-14 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Gene3D G3DSA:3.40.50.740 519 791 3.1E-78 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Gene3D G3DSA:2.20.25.90 256 321 5.4E-17 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Gene3D G3DSA:2.40.40.20 792 939 4.0E-27 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 196 207 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 SUPERFAMILY SSF50692 799 938 2.71E-34 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Gene3D G3DSA:3.10.20.30 1 126 1.3E-15 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 SUPERFAMILY SSF54862 139 220 2.72E-17 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Pfam PF00037 4Fe-4S binding domain 147 164 4.8E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Pfam PF00037 4Fe-4S binding domain 189 211 3.1E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 SUPERFAMILY SSF53706 257 787 6.54E-193 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Pfam PF01568 Molydopterin dinucleotide binding domain 826 933 1.1E-20 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 268 936 6.1E-245 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Gene3D G3DSA:3.40.50.740 322 518 9.5E-46 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 SMART SM00926 263 317 9.7E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 PIRSF PIRSF036643 2 970 0.0 T 29-03-2018 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 125 7.9E-12 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Pfam PF00384 Molybdopterin oxidoreductase 320 743 2.2E-85 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 264 317 2.0E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS12520 82c33f4448a23236bec337e9c0c42c3a 980 SUPERFAMILY SSF54292 7 129 1.55E-31 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CXR48_RS01030 b100df72c6e7b1a237261207eb0613e0 637 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 38 387 1.5E-119 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CXR48_RS01030 b100df72c6e7b1a237261207eb0613e0 637 Gene3D G3DSA:3.20.20.300 21 414 3.4E-107 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CXR48_RS01030 b100df72c6e7b1a237261207eb0613e0 637 SUPERFAMILY SSF51445 21 429 1.68E-101 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS01030 b100df72c6e7b1a237261207eb0613e0 637 SUPERFAMILY SSF52279 431 630 1.05E-8 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CXR48_RS01030 b100df72c6e7b1a237261207eb0613e0 637 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 431 617 5.6E-15 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CXR48_RS01030 b100df72c6e7b1a237261207eb0613e0 637 Gene3D G3DSA:3.40.50.1700 415 630 1.9E-16 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CXR48_RS01030 b100df72c6e7b1a237261207eb0613e0 637 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 299 316 - T 29-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 140 7.8E-33 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 SMART SM00859 2 141 3.7E-45 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 316 9.0E-30 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 339 42.63 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 Gene3D G3DSA:3.40.50.720 1 155 3.1E-35 T 29-03-2018 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 Gene3D G3DSA:3.30.360.10 156 313 1.8E-60 T 29-03-2018 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 345 6.0E-139 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 SUPERFAMILY SSF55347 149 313 1.57E-56 T 29-03-2018 CXR48_RS05485 2d2ac39bf5708afa944d418eb756b179 345 SUPERFAMILY SSF51735 2 175 3.1E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11635 0475b48fbd57699c62567d76108d84ef 426 Gene3D G3DSA:2.30.42.10 114 218 7.5E-16 T 29-03-2018 CXR48_RS11635 0475b48fbd57699c62567d76108d84ef 426 Pfam PF05580 SpoIVB peptidase S55 204 412 2.9E-87 T 29-03-2018 IPR008763 Peptidase S55, SpoIVB CXR48_RS11635 0475b48fbd57699c62567d76108d84ef 426 SMART SM00228 111 187 8.5E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS11635 0475b48fbd57699c62567d76108d84ef 426 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 3 417 8.9E-177 T 29-03-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B CXR48_RS11635 0475b48fbd57699c62567d76108d84ef 426 SUPERFAMILY SSF50494 347 411 5.68E-7 T 29-03-2018 IPR009003 Peptidase S1, PA clan CXR48_RS11635 0475b48fbd57699c62567d76108d84ef 426 Gene3D G3DSA:2.40.10.10 306 415 1.4E-4 T 29-03-2018 CXR48_RS11635 0475b48fbd57699c62567d76108d84ef 426 SUPERFAMILY SSF50156 132 194 3.29E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS11635 0475b48fbd57699c62567d76108d84ef 426 Pfam PF13180 PDZ domain 136 192 5.8E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 2.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 2.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 2.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 2.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 2.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 SMART SM00846 3 152 2.1E-99 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.6E-72 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 2.8E-141 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 SUPERFAMILY SSF55347 152 314 1.55E-74 T 29-03-2018 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 PIRSF PIRSF000149 1 334 4.9E-143 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 SUPERFAMILY SSF51735 3 168 3.21E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 Gene3D G3DSA:3.30.360.10 162 315 1.3E-72 T 29-03-2018 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.3E-40 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 Gene3D G3DSA:3.40.50.720 1 161 8.5E-82 T 29-03-2018 CXR48_RS16035 6971077534b6d5643f921807b60b819d 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 Gene3D G3DSA:1.10.238.10 9 233 0.13 T 29-03-2018 CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 SUPERFAMILY SSF47384 339 422 5.3E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 SUPERFAMILY SSF55874 414 578 4.85E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 Gene3D G3DSA:3.30.565.10 438 580 2.6E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 Pfam PF00512 His Kinase A (phospho-acceptor) domain 357 417 1.1E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 SMART SM00388 356 424 2.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 578 5.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 SMART SM00387 470 580 5.5E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 Gene3D G3DSA:1.10.287.130 341 420 4.2E-11 T 29-03-2018 CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 559 2.0E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 578 2.0E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 535 2.0E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS15550 1468b7b9f68d0672c49383fd8ab18590 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 521 2.0E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 Gene3D G3DSA:2.60.40.1180 480 561 4.6E-21 T 29-03-2018 CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 Gene3D G3DSA:3.20.20.80 346 473 4.3E-21 T 29-03-2018 CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 Pfam PF00128 Alpha amylase, catalytic domain 31 377 3.6E-129 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 SMART SM00642 16 419 2.2E-164 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 Gene3D G3DSA:3.20.20.470 174 345 1.0E-37 T 29-03-2018 CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 Gene3D G3DSA:3.90.400.10 108 173 8.5E-29 T 29-03-2018 CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 Pfam PF16657 Maltogenic Amylase, C-terminal domain 480 552 3.0E-12 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 8 557 1.4E-265 T 29-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 SUPERFAMILY SSF51011 480 558 3.96E-17 T 29-03-2018 CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 SUPERFAMILY SSF51445 7 475 1.13E-154 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS03815 5edbe050b32533f6da1450017e80e351 561 Gene3D G3DSA:3.20.20.470 2 98 4.9E-36 T 29-03-2018 CXR48_RS05680 b27c011fde400a56faf7094323218aae 228 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 128 156 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CXR48_RS05680 b27c011fde400a56faf7094323218aae 228 Pfam PF01464 Transglycosylase SLT domain 110 217 2.9E-35 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CXR48_RS05680 b27c011fde400a56faf7094323218aae 228 Gene3D G3DSA:1.10.530.10 64 228 8.7E-51 T 29-03-2018 CXR48_RS05680 b27c011fde400a56faf7094323218aae 228 SUPERFAMILY SSF53955 96 226 4.5E-49 T 29-03-2018 IPR023346 Lysozyme-like domain CXR48_RS14250 d56b253321779f9318376ff81b2bcb6d 276 Pfam PF00561 alpha/beta hydrolase fold 28 261 3.0E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14250 d56b253321779f9318376ff81b2bcb6d 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 2.2E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14250 d56b253321779f9318376ff81b2bcb6d 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 2.2E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14250 d56b253321779f9318376ff81b2bcb6d 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 2.2E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14250 d56b253321779f9318376ff81b2bcb6d 276 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 26 273 1.4E-85 T 29-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CXR48_RS14250 d56b253321779f9318376ff81b2bcb6d 276 Gene3D G3DSA:3.40.50.1820 12 275 5.7E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14250 d56b253321779f9318376ff81b2bcb6d 276 SUPERFAMILY SSF53474 5 273 1.21E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14250 d56b253321779f9318376ff81b2bcb6d 276 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 23 274 35.855 T 29-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CXR48_RS19265 b58947640a46595cc4f9ec298d3360f0 166 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CXR48_RS19265 b58947640a46595cc4f9ec298d3360f0 166 Pfam PF02082 Transcriptional regulator 1 83 3.7E-27 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CXR48_RS19265 b58947640a46595cc4f9ec298d3360f0 166 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 141 6.1E-32 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CXR48_RS19265 b58947640a46595cc4f9ec298d3360f0 166 SUPERFAMILY SSF46785 3 145 1.98E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19265 b58947640a46595cc4f9ec298d3360f0 166 Gene3D G3DSA:1.10.10.10 1 156 8.2E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02445 a54c907e3d60c3ee12346df68aa9ea19 133 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 127 4.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02445 a54c907e3d60c3ee12346df68aa9ea19 133 Gene3D G3DSA:3.30.565.10 10 129 1.3E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02445 a54c907e3d60c3ee12346df68aa9ea19 133 SUPERFAMILY SSF55874 21 127 1.57E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02445 a54c907e3d60c3ee12346df68aa9ea19 133 SMART SM00387 34 133 2.6E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 Pfam PF00067 Cytochrome P450 163 354 1.0E-26 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 Gene3D G3DSA:1.10.630.10 2 384 5.7E-74 T 29-03-2018 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 327 336 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 PRINTS PR00359 B-class P450 signature 142 157 2.6E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 PRINTS PR00359 B-class P450 signature 325 334 2.6E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 PRINTS PR00359 B-class P450 signature 178 200 2.6E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 PRINTS PR00359 B-class P450 signature 259 270 2.6E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 PRINTS PR00359 B-class P450 signature 276 303 2.6E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 PRINTS PR00359 B-class P450 signature 334 345 2.6E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 PRINTS PR00359 B-class P450 signature 304 319 2.6E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 PRINTS PR00359 B-class P450 signature 79 90 2.6E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 PRINTS PR00359 B-class P450 signature 125 141 2.6E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS11325 0589798d1d9116d0f07b75ed34ee2295 384 SUPERFAMILY SSF48264 7 384 4.06E-92 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 SUPERFAMILY SSF82057 196 277 1.34E-15 T 29-03-2018 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 Gene3D G3DSA:2.30.30.170 197 281 2.1E-13 T 29-03-2018 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 Pfam PF13457 SH3-like domain 204 275 2.0E-11 T 29-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 58 193 3.6E-23 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 Gene3D G3DSA:1.10.530.10 44 196 2.3E-37 T 29-03-2018 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 SMART SM00047 39 197 1.7E-65 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 PRINTS PR01002 Flagellar protein FlgJ signature 69 87 5.6E-9 T 29-03-2018 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 PRINTS PR01002 Flagellar protein FlgJ signature 154 173 5.6E-9 T 29-03-2018 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 PRINTS PR01002 Flagellar protein FlgJ signature 174 192 5.6E-9 T 29-03-2018 CXR48_RS14445 0775e2e13aacbe63cfd4bf848fcdd6e0 281 PRINTS PR01002 Flagellar protein FlgJ signature 45 68 5.6E-9 T 29-03-2018 CXR48_RS17530 1365da38ab99dd43f9381595b4f6c7c4 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 4.4E-31 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS17530 1365da38ab99dd43f9381595b4f6c7c4 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS17530 1365da38ab99dd43f9381595b4f6c7c4 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 66 28.649 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS17530 1365da38ab99dd43f9381595b4f6c7c4 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.6E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS17530 1365da38ab99dd43f9381595b4f6c7c4 66 PRINTS PR01249 Ribosomal protein L31 signature 30 45 3.6E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS17530 1365da38ab99dd43f9381595b4f6c7c4 66 PRINTS PR01249 Ribosomal protein L31 signature 45 63 3.6E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS17530 1365da38ab99dd43f9381595b4f6c7c4 66 SUPERFAMILY SSF143800 1 65 1.96E-25 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS17530 1365da38ab99dd43f9381595b4f6c7c4 66 Pfam PF01197 Ribosomal protein L31 1 64 1.7E-31 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS17395 e6612112b138529c678a9aa2c42b6ed6 132 Gene3D G3DSA:2.60.15.10 1 88 1.7E-29 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17395 e6612112b138529c678a9aa2c42b6ed6 132 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 86 6.0E-37 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17395 e6612112b138529c678a9aa2c42b6ed6 132 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 82 2.9E-30 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17395 e6612112b138529c678a9aa2c42b6ed6 132 SUPERFAMILY SSF46604 87 130 8.37E-10 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17395 e6612112b138529c678a9aa2c42b6ed6 132 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 86 131 2.5E-15 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17395 e6612112b138529c678a9aa2c42b6ed6 132 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 130 4.3E-43 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17395 e6612112b138529c678a9aa2c42b6ed6 132 Gene3D G3DSA:1.20.5.440 89 130 1.4E-14 T 29-03-2018 CXR48_RS17395 e6612112b138529c678a9aa2c42b6ed6 132 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 23.678 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17395 e6612112b138529c678a9aa2c42b6ed6 132 SUPERFAMILY SSF51344 3 84 4.32E-25 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 250 9.2E-70 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 SUPERFAMILY SSF53067 7 253 1.97E-69 T 29-03-2018 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 454 2.0E-34 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 PIRSF PIRSF000538 4 506 1.4E-148 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 Gene3D G3DSA:3.30.420.40 248 514 7.4E-68 T 29-03-2018 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 7 509 2.9E-204 T 29-03-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 Gene3D G3DSA:3.30.420.40 1 247 7.0E-70 T 29-03-2018 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS16085 af6ba81f228d689313f685a4f994b810 514 SUPERFAMILY SSF53067 252 501 2.22E-67 T 29-03-2018 CXR48_RS02835 aac9d684009338debb1d9be48e64fd17 403 SUPERFAMILY SSF103473 5 400 5.62E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS02835 aac9d684009338debb1d9be48e64fd17 403 Pfam PF07690 Major Facilitator Superfamily 19 359 4.7E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS02835 aac9d684009338debb1d9be48e64fd17 403 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 9 394 5.5E-138 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CXR48_RS02835 aac9d684009338debb1d9be48e64fd17 403 Gene3D G3DSA:1.20.1250.20 7 199 1.3E-25 T 29-03-2018 CXR48_RS02835 aac9d684009338debb1d9be48e64fd17 403 Gene3D G3DSA:1.20.1250.20 204 403 2.9E-16 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SUPERFAMILY SSF47336 956 1026 5.37E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:3.30.559.10 1 187 5.3E-27 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SUPERFAMILY SSF56801 1473 2050 1.22E-162 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:3.30.559.10 1029 1249 3.1E-45 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:2.30.38.10 765 845 2.2E-26 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:3.40.50.980 448 608 6.1E-49 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SUPERFAMILY SSF56801 419 974 1.83E-160 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:3.40.50.1820 2108 2369 3.5E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SUPERFAMILY SSF52777 192 444 1.06E-35 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Pfam PF00501 AMP-binding enzyme 1514 1929 5.4E-101 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Pfam PF00501 AMP-binding enzyme 457 855 3.0E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SMART SM00823 Phosphopantetheine attachment site 2037 2106 2.1E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SMART SM00823 Phosphopantetheine attachment site 961 1030 3.7E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:1.10.1200.10 967 1028 4.6E-22 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:1.10.1200.10 2043 2107 4.2E-23 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Pfam PF00975 Thioesterase domain 2125 2259 2.5E-31 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Pfam PF13193 AMP-binding enzyme C-terminal domain 863 936 2.1E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Pfam PF13193 AMP-binding enzyme C-terminal domain 1937 2012 1.4E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SMART SM00824 Thioesterase 2127 2364 3.3E-5 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SUPERFAMILY SSF52777 1047 1219 6.56E-48 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 478 879 1.1E-134 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1535 1952 4.4E-138 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SUPERFAMILY SSF53474 2105 2368 1.02E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1664 1675 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SUPERFAMILY SSF47336 2031 2103 2.22E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SUPERFAMILY SSF52777 9 183 5.45E-36 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Pfam PF00668 Condensation domain 1043 1495 1.4E-95 T 29-03-2018 IPR001242 Condensation domain CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Pfam PF00668 Condensation domain 5 434 5.7E-68 T 29-03-2018 IPR001242 Condensation domain CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:3.40.50.980 1507 1668 3.1E-43 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:2.30.38.10 1841 1922 1.5E-22 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:3.40.50.980 1669 1835 8.5E-40 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:3.40.50.980 609 763 2.4E-35 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:3.30.300.30 1924 2042 1.0E-40 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Gene3D G3DSA:3.30.300.30 850 966 3.0E-36 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 SUPERFAMILY SSF52777 1232 1483 2.89E-59 T 29-03-2018 CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Pfam PF00550 Phosphopantetheine attachment site 964 1025 4.4E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS14880 7f5aa685bb93635ff37869f0dc796435 2375 Pfam PF00550 Phosphopantetheine attachment site 2040 2102 2.5E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS06580 5ccbd85151de27d6ff35ea01a733ea19 545 Gene3D G3DSA:3.40.50.300 288 538 4.5E-64 T 29-03-2018 CXR48_RS06580 5ccbd85151de27d6ff35ea01a733ea19 545 Gene3D G3DSA:3.40.50.300 3 245 1.3E-56 T 29-03-2018 CXR48_RS06580 5ccbd85151de27d6ff35ea01a733ea19 545 ProSitePatterns PS00211 ABC transporters family signature. 422 436 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS06580 5ccbd85151de27d6ff35ea01a733ea19 545 Pfam PF00005 ABC transporter 25 175 7.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS06580 5ccbd85151de27d6ff35ea01a733ea19 545 Pfam PF00005 ABC transporter 309 449 1.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS06580 5ccbd85151de27d6ff35ea01a733ea19 545 SUPERFAMILY SSF52540 282 515 1.9E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS06580 5ccbd85151de27d6ff35ea01a733ea19 545 SMART SM00382 317 499 2.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS06580 5ccbd85151de27d6ff35ea01a733ea19 545 SMART SM00382 34 246 5.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS06580 5ccbd85151de27d6ff35ea01a733ea19 545 SUPERFAMILY SSF52540 6 237 1.82E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 Pfam PF07690 Major Facilitator Superfamily 16 270 4.1E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 SUPERFAMILY SSF103473 1 390 1.02E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 Gene3D G3DSA:1.20.1250.20 197 390 3.4E-22 T 29-03-2018 CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 PRINTS PR01035 Tetracycline resistance protein signature 341 364 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 PRINTS PR01035 Tetracycline resistance protein signature 253 273 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 PRINTS PR01035 Tetracycline resistance protein signature 21 37 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 PRINTS PR01035 Tetracycline resistance protein signature 136 158 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 PRINTS PR01035 Tetracycline resistance protein signature 164 184 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS05255 bd9c626f2920f852e4d345f393e9f5b3 398 Gene3D G3DSA:1.20.1250.20 6 196 6.5E-45 T 29-03-2018 CXR48_RS10060 9fb1ebf69a3a0caa21b06beaf19e6be5 558 Pfam PF00920 Dehydratase family 34 553 9.5E-229 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CXR48_RS10060 9fb1ebf69a3a0caa21b06beaf19e6be5 558 SUPERFAMILY SSF52016 377 556 8.63E-63 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CXR48_RS10060 9fb1ebf69a3a0caa21b06beaf19e6be5 558 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 557 48.066 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CXR48_RS10060 9fb1ebf69a3a0caa21b06beaf19e6be5 558 SUPERFAMILY SSF143975 3 376 3.14E-141 T 29-03-2018 CXR48_RS10060 9fb1ebf69a3a0caa21b06beaf19e6be5 558 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 17 557 6.3E-271 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CXR48_RS10060 9fb1ebf69a3a0caa21b06beaf19e6be5 558 Gene3D G3DSA:3.40.50.2300 37 257 0.0037 T 29-03-2018 CXR48_RS10060 9fb1ebf69a3a0caa21b06beaf19e6be5 558 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CXR48_RS10060 9fb1ebf69a3a0caa21b06beaf19e6be5 558 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 470 1.3E-33 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 Pfam PF00391 PEP-utilising enzyme, mobile domain 504 575 1.4E-22 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 Gene3D G3DSA:3.40.1380.20 322 473 2.1E-55 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 SUPERFAMILY SSF50800 71 167 4.19E-25 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 SUPERFAMILY SSF51621 2 74 1.95E-105 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 SUPERFAMILY SSF51621 156 343 1.95E-105 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 Gene3D G3DSA:3.20.20.60 95 321 8.0E-82 T 29-03-2018 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 Gene3D G3DSA:3.20.20.60 1 94 3.8E-21 T 29-03-2018 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 7.4E-195 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 Pfam PF00224 Pyruvate kinase, barrel domain 2 343 3.2E-157 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 SUPERFAMILY SSF52009 465 582 1.19E-30 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.5E-79 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.5E-79 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.5E-79 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.5E-79 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 PRINTS PR01050 Pyruvate kinase family signature 186 200 1.5E-79 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.5E-79 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.5E-79 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 SUPERFAMILY SSF52935 323 473 5.76E-41 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CXR48_RS13500 efae4bfd65c397f8b2e6bf994c153ad8 585 Gene3D G3DSA:3.50.30.10 474 585 8.7E-31 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 Gene3D G3DSA:1.10.1160.10 247 333 4.6E-29 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 Gene3D G3DSA:1.10.8.70 334 384 2.5E-6 T 29-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 SUPERFAMILY SSF48163 298 482 4.45E-49 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 Gene3D G3DSA:3.40.50.620 5 129 2.1E-40 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 483 34.37 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 1.9E-129 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 SUPERFAMILY SSF52374 5 316 7.51E-116 T 29-03-2018 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 9.6E-30 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 9.6E-30 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 9.6E-30 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 9.6E-30 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 9.6E-30 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 Gene3D G3DSA:3.40.50.620 130 246 4.1E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 Gene3D G3DSA:1.10.10.350 386 483 1.6E-29 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS00610 45163a2f097f4da4a9921120efb8fcbe 483 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 481 2.9E-206 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CXR48_RS15085 405f6aaa12936ac2555195a19b394d4d 256 SUPERFAMILY SSF56784 3 253 1.87E-76 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS15085 405f6aaa12936ac2555195a19b394d4d 256 PIRSF PIRSF000915 1 256 1.5E-60 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CXR48_RS15085 405f6aaa12936ac2555195a19b394d4d 256 Pfam PF13242 HAD-hyrolase-like 179 251 1.4E-21 T 29-03-2018 CXR48_RS15085 405f6aaa12936ac2555195a19b394d4d 256 Gene3D G3DSA:3.40.50.10490 18 78 5.1E-4 T 29-03-2018 CXR48_RS15085 405f6aaa12936ac2555195a19b394d4d 256 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 252 9.9E-139 T 29-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 CXR48_RS15085 405f6aaa12936ac2555195a19b394d4d 256 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 106 4.8E-29 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CXR48_RS15085 405f6aaa12936ac2555195a19b394d4d 256 Gene3D G3DSA:3.40.50.1000 79 173 9.7E-32 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS15085 405f6aaa12936ac2555195a19b394d4d 256 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 228 1.9E-41 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CXR48_RS15085 405f6aaa12936ac2555195a19b394d4d 256 Gene3D G3DSA:3.40.50.1000 174 235 0.12 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 13 458 6.7E-112 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 PRINTS PR00171 Sugar transporter signature 277 287 2.0E-21 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 PRINTS PR00171 Sugar transporter signature 117 136 2.0E-21 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 PRINTS PR00171 Sugar transporter signature 363 384 2.0E-21 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 PRINTS PR00171 Sugar transporter signature 386 398 2.0E-21 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 PRINTS PR00171 Sugar transporter signature 34 44 2.0E-21 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 SUPERFAMILY SSF103473 15 459 1.02E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 Gene3D G3DSA:1.20.1250.20 234 464 2.4E-39 T 29-03-2018 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 Gene3D G3DSA:1.20.1250.20 16 224 1.3E-36 T 29-03-2018 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 97 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 Pfam PF00083 Sugar (and other) transporter 30 462 1.3E-112 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CXR48_RS16045 53e9b70630388379e2bf16cb256705cf 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 321 338 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 SUPERFAMILY SSF52440 1 127 2.01E-50 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 SMART SM00851 949 1036 7.9E-27 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 SUPERFAMILY SSF56059 666 927 1.63E-101 T 29-03-2018 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Gene3D G3DSA:3.30.470.20 738 920 7.0E-40 T 29-03-2018 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 2.1E-38 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 2.9E-77 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 SUPERFAMILY SSF48108 395 546 1.05E-47 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Gene3D G3DSA:3.30.470.20 120 400 7.0E-67 T 29-03-2018 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 SMART SM01096 420 540 6.0E-66 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Gene3D G3DSA:3.40.50.1380 921 1049 1.7E-34 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Gene3D G3DSA:1.10.1030.10 401 531 5.3E-49 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 7.0E-40 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 6.5E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 6.5E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 6.5E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 6.5E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 6.5E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 6.5E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 6.5E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.127 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1063 13.552 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 SUPERFAMILY SSF52440 550 668 1.73E-47 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Gene3D G3DSA:3.40.50.20 532 647 9.2E-60 T 29-03-2018 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Pfam PF02142 MGS-like domain 953 1036 1.9E-18 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 SUPERFAMILY SSF56059 128 399 1.06E-107 T 29-03-2018 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Gene3D G3DSA:3.30.1490.20 648 737 2.6E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 SUPERFAMILY SSF52335 935 1053 1.57E-31 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS07730 55bad20fbeb4e4bc0a379301aab2b77f 1071 Gene3D G3DSA:3.40.50.20 4 117 2.5E-38 T 29-03-2018 CXR48_RS18185 6b627565f9f6c99f2c2b4689f14b82f3 127 Gene3D G3DSA:3.10.180.10 1 127 1.4E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS18185 6b627565f9f6c99f2c2b4689f14b82f3 127 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CXR48_RS18185 6b627565f9f6c99f2c2b4689f14b82f3 127 SUPERFAMILY SSF54593 4 127 6.31E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS18185 6b627565f9f6c99f2c2b4689f14b82f3 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 3.9E-17 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 67 401 1.0E-92 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 403 5.8E-150 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 Gene3D G3DSA:3.40.1160.10 1 239 2.7E-62 T 29-03-2018 CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 Pfam PF00696 Amino acid kinase family 2 235 4.2E-48 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 SUPERFAMILY SSF53633 3 247 3.53E-68 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 Gene3D G3DSA:3.30.70.260 240 332 3.2E-13 T 29-03-2018 CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 SUPERFAMILY SSF55021 334 403 1.29E-15 T 29-03-2018 CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 SUPERFAMILY SSF55021 260 346 1.14E-11 T 29-03-2018 CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 Gene3D G3DSA:3.30.2130.10 333 404 2.7E-12 T 29-03-2018 CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 PIRSF PIRSF000726 1 65 8.8E-8 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 PIRSF PIRSF000726 61 404 2.6E-88 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 Pfam PF13840 ACT domain 336 398 4.0E-21 T 29-03-2018 IPR027795 GATS-like ACT domain CXR48_RS08360 19739ae64f596fc638b69abda2caf54b 404 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS15785 73ead74f9822ead161a8501c6979d324 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 225 7.8E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15785 73ead74f9822ead161a8501c6979d324 240 SUPERFAMILY SSF161098 15 215 2.62E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15785 73ead74f9822ead161a8501c6979d324 240 Gene3D G3DSA:1.10.3720.10 4 229 3.2E-38 T 29-03-2018 CXR48_RS15785 73ead74f9822ead161a8501c6979d324 240 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 118 7.5E-21 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 SUPERFAMILY SSF52540 161 468 2.62E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:1.10.1780.10 1 76 7.4E-24 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 317 1.6E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF02151 UvrB/uvrC motif 417 452 4.9E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 SUPERFAMILY SSF52540 486 802 3.11E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 SMART SM01086 714 803 1.4E-35 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:3.40.50.300 193 342 3.6E-20 T 29-03-2018 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:3.40.50.300 492 713 2.1E-56 T 29-03-2018 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 662 1.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 541 559 1.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 586 604 1.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 615 633 1.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:1.10.8.60 714 809 3.3E-25 T 29-03-2018 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 714 793 4.2E-25 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 SMART SM00382 200 343 1.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 SMART SM00382 537 715 3.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 571 589 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 2.1E-17 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.0E-18 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF07724 AAA domain (Cdc48 subfamily) 536 708 2.4E-57 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 SUPERFAMILY SSF81923 5 149 8.63E-34 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:1.10.8.60 344 487 1.3E-44 T 29-03-2018 CXR48_RS00580 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:1.10.1780.10 77 192 2.6E-28 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CXR48_RS16960 d4de8e74c0482cca946befedc9c0865a 323 Gene3D G3DSA:1.10.3470.10 35 321 1.2E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS16960 d4de8e74c0482cca946befedc9c0865a 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 315 1.4E-52 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CXR48_RS11495 71a4939769dbdb537bb70a3afd07b72c 255 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 252 1.6E-64 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS11495 71a4939769dbdb537bb70a3afd07b72c 255 SMART SM00062 33 254 2.2E-79 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS11495 71a4939769dbdb537bb70a3afd07b72c 255 Gene3D G3DSA:3.40.190.10 143 255 7.2E-17 T 29-03-2018 CXR48_RS11495 71a4939769dbdb537bb70a3afd07b72c 255 Gene3D G3DSA:3.40.190.10 16 142 3.3E-40 T 29-03-2018 CXR48_RS11495 71a4939769dbdb537bb70a3afd07b72c 255 SMART SM00079 33 253 2.5E-6 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CXR48_RS11495 71a4939769dbdb537bb70a3afd07b72c 255 SUPERFAMILY SSF53850 1 253 3.63E-71 T 29-03-2018 CXR48_RS06720 bcea669ccfc52cd9f6a548a5e5d04357 394 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 36 390 1.2E-160 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CXR48_RS06720 bcea669ccfc52cd9f6a548a5e5d04357 394 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 394 187.342 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CXR48_RS06720 bcea669ccfc52cd9f6a548a5e5d04357 394 Gene3D G3DSA:3.30.200.20 1 119 2.3E-37 T 29-03-2018 CXR48_RS06720 bcea669ccfc52cd9f6a548a5e5d04357 394 PIRSF PIRSF031134 4 393 5.5E-152 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CXR48_RS06720 bcea669ccfc52cd9f6a548a5e5d04357 394 Gene3D G3DSA:3.90.1200.10 123 365 3.4E-16 T 29-03-2018 CXR48_RS06720 bcea669ccfc52cd9f6a548a5e5d04357 394 Pfam PF01636 Phosphotransferase enzyme family 35 269 7.4E-14 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CXR48_RS06720 bcea669ccfc52cd9f6a548a5e5d04357 394 SUPERFAMILY SSF56112 7 388 1.79E-92 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS19385 55d3e6a4d5d64bad355e77048cc42696 204 Gene3D G3DSA:3.40.50.1450 7 175 6.1E-37 T 29-03-2018 IPR023430 Peptidase HybD-like domain CXR48_RS19385 55d3e6a4d5d64bad355e77048cc42696 204 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 42 181 7.6E-70 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CXR48_RS19385 55d3e6a4d5d64bad355e77048cc42696 204 Pfam PF06866 Protein of unknown function (DUF1256) 17 179 1.9E-67 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CXR48_RS19385 55d3e6a4d5d64bad355e77048cc42696 204 SUPERFAMILY SSF53163 13 193 9.68E-56 T 29-03-2018 IPR023430 Peptidase HybD-like domain CXR48_RS05250 4688ca403d36c072e3c31f1dd24ae710 385 Pfam PF05145 Transition state regulatory protein AbrB 33 365 1.7E-83 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CXR48_RS05250 4688ca403d36c072e3c31f1dd24ae710 385 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 11 172 1.2E-37 T 29-03-2018 IPR017516 AbrB duplication CXR48_RS05250 4688ca403d36c072e3c31f1dd24ae710 385 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 206 365 3.5E-34 T 29-03-2018 IPR017516 AbrB duplication CXR48_RS05250 4688ca403d36c072e3c31f1dd24ae710 385 PIRSF PIRSF038991 1 374 7.6E-99 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CXR48_RS13020 def2750f8e86f50e68ef8845a75924ed 334 Pfam PF14559 Tetratricopeptide repeat 27 81 1.4E-9 T 29-03-2018 CXR48_RS13020 def2750f8e86f50e68ef8845a75924ed 334 Gene3D G3DSA:1.25.40.10 17 321 1.0E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS13020 def2750f8e86f50e68ef8845a75924ed 334 SUPERFAMILY SSF116965 81 291 2.09E-8 T 29-03-2018 CXR48_RS13020 def2750f8e86f50e68ef8845a75924ed 334 SUPERFAMILY SSF48452 14 121 1.39E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS14825 abeecc57cedd5ccba8ba9c506ccce86f 243 SUPERFAMILY SSF51735 4 230 9.38E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS14825 abeecc57cedd5ccba8ba9c506ccce86f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.1E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS14825 abeecc57cedd5ccba8ba9c506ccce86f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.1E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS14825 abeecc57cedd5ccba8ba9c506ccce86f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.1E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS14825 abeecc57cedd5ccba8ba9c506ccce86f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.1E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS14825 abeecc57cedd5ccba8ba9c506ccce86f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.1E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS14825 abeecc57cedd5ccba8ba9c506ccce86f 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS14825 abeecc57cedd5ccba8ba9c506ccce86f 243 Gene3D G3DSA:3.40.50.720 1 241 2.3E-40 T 29-03-2018 CXR48_RS14825 abeecc57cedd5ccba8ba9c506ccce86f 243 Pfam PF00106 short chain dehydrogenase 4 192 3.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13280 7c87845d674f80dad5dad3d15a2c59d2 431 Gene3D G3DSA:3.40.190.10 33 213 2.2E-34 T 29-03-2018 CXR48_RS13280 7c87845d674f80dad5dad3d15a2c59d2 431 SUPERFAMILY SSF53850 32 430 1.41E-61 T 29-03-2018 CXR48_RS13280 7c87845d674f80dad5dad3d15a2c59d2 431 Gene3D G3DSA:3.40.190.10 214 377 4.4E-10 T 29-03-2018 CXR48_RS13280 7c87845d674f80dad5dad3d15a2c59d2 431 Pfam PF01547 Bacterial extracellular solute-binding protein 44 334 7.7E-41 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CXR48_RS00620 d3e4ca559417c172fd0c6168c79eb04f 217 Gene3D G3DSA:1.10.3130.10 2 62 1.2E-27 T 29-03-2018 CXR48_RS00620 d3e4ca559417c172fd0c6168c79eb04f 217 SUPERFAMILY SSF51161 3 169 3.6E-56 T 29-03-2018 IPR011004 Trimeric LpxA-like CXR48_RS00620 d3e4ca559417c172fd0c6168c79eb04f 217 Gene3D G3DSA:2.160.10.10 63 216 7.2E-39 T 29-03-2018 CXR48_RS00620 d3e4ca559417c172fd0c6168c79eb04f 217 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 73 109 0.0014 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS00620 d3e4ca559417c172fd0c6168c79eb04f 217 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 6.0E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS00620 d3e4ca559417c172fd0c6168c79eb04f 217 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 7 167 9.9E-78 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CXR48_RS00620 d3e4ca559417c172fd0c6168c79eb04f 217 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 127 155 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CXR48_RS00620 d3e4ca559417c172fd0c6168c79eb04f 217 Pfam PF06426 Serine acetyltransferase, N-terminal 5 36 1.9E-4 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CXR48_RS00620 d3e4ca559417c172fd0c6168c79eb04f 217 PIRSF PIRSF000441 1 217 1.7E-83 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 Pfam PF00698 Acyl transferase domain 3 271 1.6E-34 T 29-03-2018 IPR014043 Acyl transferase CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 PIRSF PIRSF000446 1 289 1.1E-105 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 SUPERFAMILY SSF55048 121 176 8.63E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 SUPERFAMILY SSF52151 1 117 4.45E-63 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 SUPERFAMILY SSF52151 182 285 4.45E-63 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 289 2.7E-22 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 282 8.3E-121 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 Gene3D G3DSA:3.40.366.10 185 288 6.2E-21 T 29-03-2018 CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 Gene3D G3DSA:3.30.70.250 131 184 1.4E-16 T 29-03-2018 CXR48_RS08525 3b25b227381b9f8d92d6e8279757ce71 289 Gene3D G3DSA:3.40.366.10 1 130 3.4E-32 T 29-03-2018 CXR48_RS11965 a318b7f0c89d8e2a1169b71156a37ab5 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS11965 a318b7f0c89d8e2a1169b71156a37ab5 49 Pfam PF00471 Ribosomal protein L33 3 49 4.3E-22 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS11965 a318b7f0c89d8e2a1169b71156a37ab5 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.083 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS11965 a318b7f0c89d8e2a1169b71156a37ab5 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 2.3E-19 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS11965 a318b7f0c89d8e2a1169b71156a37ab5 49 SUPERFAMILY SSF57829 1 49 1.59E-18 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CXR48_RS07070 c14de877a183228a9ce1696272057c29 156 SUPERFAMILY SSF54690 4 136 1.19E-45 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CXR48_RS07070 c14de877a183228a9ce1696272057c29 156 Gene3D G3DSA:3.90.1170.40 1 142 1.6E-49 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CXR48_RS07070 c14de877a183228a9ce1696272057c29 156 Pfam PF02391 MoaE protein 6 117 1.4E-37 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CXR48_RS09270 19c04fda0755350f451f47b4ed5f070d 462 Pfam PF01554 MatE 256 417 4.5E-34 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS09270 19c04fda0755350f451f47b4ed5f070d 462 Pfam PF01554 MatE 27 186 5.1E-40 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS09270 19c04fda0755350f451f47b4ed5f070d 462 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 430 6.5E-106 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS09270 19c04fda0755350f451f47b4ed5f070d 462 PIRSF PIRSF006603 3 462 1.9E-140 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS18935 9a572e46187314968556f289f21cea0f 371 Gene3D G3DSA:1.25.40.10 145 370 3.2E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS18935 9a572e46187314968556f289f21cea0f 371 SMART SM00028 213 246 0.023 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS18935 9a572e46187314968556f289f21cea0f 371 SMART SM00028 132 165 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS18935 9a572e46187314968556f289f21cea0f 371 SMART SM00028 326 359 30.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS18935 9a572e46187314968556f289f21cea0f 371 SMART SM00028 173 206 460.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS18935 9a572e46187314968556f289f21cea0f 371 SMART SM00028 252 285 59.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS18935 9a572e46187314968556f289f21cea0f 371 SUPERFAMILY SSF48452 111 310 2.19E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS18935 9a572e46187314968556f289f21cea0f 371 Gene3D G3DSA:1.25.40.10 1 144 2.3E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS06585 4a84697f94b078d14ec39a21cd3ff38b 199 Pfam PF09819 ABC-type cobalt transport system, permease component 7 125 6.0E-35 T 29-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CXR48_RS06585 4a84697f94b078d14ec39a21cd3ff38b 199 PIRSF PIRSF037394 1 191 9.4E-64 T 29-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 Gene3D G3DSA:3.90.1820.10 1 294 1.7E-72 T 29-03-2018 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 Gene3D G3DSA:3.90.1820.10 295 432 4.0E-32 T 29-03-2018 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 139 169 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 Pfam PF02056 Family 4 glycosyl hydrolase 3 184 1.0E-74 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 SUPERFAMILY SSF56327 168 431 1.81E-70 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 194 404 8.7E-64 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 SUPERFAMILY SSF51735 3 167 2.67E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 190 202 3.0E-41 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 3.0E-41 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 110 130 3.0E-41 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 3 18 3.0E-41 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 94 107 3.0E-41 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 139 156 3.0E-41 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS13980 e8c2b55f1073cd60fc95569ff2f8d169 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 72 88 3.0E-41 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS05815 20e6e304fc34980fc974ce96c9f41fbf 761 Gene3D G3DSA:3.40.50.300 403 758 3.8E-53 T 29-03-2018 CXR48_RS05815 20e6e304fc34980fc974ce96c9f41fbf 761 Pfam PF00580 UvrD/REP helicase N-terminal domain 137 400 2.9E-63 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CXR48_RS05815 20e6e304fc34980fc974ce96c9f41fbf 761 SUPERFAMILY SSF52540 135 751 2.85E-134 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05815 20e6e304fc34980fc974ce96c9f41fbf 761 Pfam PF13361 UvrD-like helicase C-terminal domain 644 732 6.1E-23 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CXR48_RS05815 20e6e304fc34980fc974ce96c9f41fbf 761 Pfam PF13361 UvrD-like helicase C-terminal domain 405 545 3.2E-17 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CXR48_RS05815 20e6e304fc34980fc974ce96c9f41fbf 761 Gene3D G3DSA:3.40.50.300 134 402 1.1E-57 T 29-03-2018 CXR48_RS11185 27f6751022ebf314dd45423f1df53b38 468 Pfam PF03553 Na+/H+ antiporter family 159 451 4.6E-70 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CXR48_RS11185 27f6751022ebf314dd45423f1df53b38 468 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 5 458 1.2E-212 T 29-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CXR48_RS03810 b36c15460b0ec91c435cb06e25ced5b4 471 Pfam PF00367 phosphotransferase system, EIIB 9 42 6.5E-14 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS03810 b36c15460b0ec91c435cb06e25ced5b4 471 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS03810 b36c15460b0ec91c435cb06e25ced5b4 471 SUPERFAMILY SSF55604 8 83 8.5E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS03810 b36c15460b0ec91c435cb06e25ced5b4 471 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 111 2.1E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS03810 b36c15460b0ec91c435cb06e25ced5b4 471 Gene3D G3DSA:3.30.1360.60 5 82 1.2E-23 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS03810 b36c15460b0ec91c435cb06e25ced5b4 471 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 464 3.9E-213 T 29-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 CXR48_RS03810 b36c15460b0ec91c435cb06e25ced5b4 471 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 165 452 2.5E-88 T 29-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS03810 b36c15460b0ec91c435cb06e25ced5b4 471 Pfam PF02378 Phosphotransferase system, EIIC 112 410 3.5E-45 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS08305 7d2531d8264bbcc7f51496d231514dd2 117 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 94 2.0E-30 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CXR48_RS08305 7d2531d8264bbcc7f51496d231514dd2 117 Gene3D G3DSA:3.30.300.20 2 114 1.3E-38 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS08305 7d2531d8264bbcc7f51496d231514dd2 117 SUPERFAMILY SSF89919 2 110 5.76E-37 T 29-03-2018 IPR023799 Ribosome-binding factor A domain CXR48_RS08305 7d2531d8264bbcc7f51496d231514dd2 117 Pfam PF02033 Ribosome-binding factor A 4 107 8.6E-36 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CXR48_RS08305 7d2531d8264bbcc7f51496d231514dd2 117 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CXR48_RS08305 7d2531d8264bbcc7f51496d231514dd2 117 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 114 23.4 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CXR48_RS08305 7d2531d8264bbcc7f51496d231514dd2 117 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 6.5E-44 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 Gene3D G3DSA:1.10.540.10 1 118 1.2E-37 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 Gene3D G3DSA:2.40.110.10 119 215 7.3E-38 T 29-03-2018 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 SUPERFAMILY SSF47203 225 376 1.55E-60 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 Gene3D G3DSA:1.20.140.10 216 377 1.3E-64 T 29-03-2018 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 2.3E-38 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 SUPERFAMILY SSF56645 2 238 4.06E-88 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 PIRSF PIRSF016578 2 366 6.6E-18 T 29-03-2018 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 5.0E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CXR48_RS11570 eeda6c8e1244a57bb38e146a78ec720b 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 3.4E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CXR48_RS08870 9d9a576516fa50fbb833c254d5b08548 103 SMART SM00257 37 88 0.0021 T 29-03-2018 IPR018392 LysM domain CXR48_RS08870 9d9a576516fa50fbb833c254d5b08548 103 Gene3D G3DSA:3.10.350.10 31 93 1.9E-10 T 29-03-2018 CXR48_RS08870 9d9a576516fa50fbb833c254d5b08548 103 Pfam PF01476 LysM domain 39 88 1.5E-8 T 29-03-2018 IPR018392 LysM domain CXR48_RS08870 9d9a576516fa50fbb833c254d5b08548 103 Hamap MF_02014 Cell division suppressor protein YneA [yneA]. 1 102 28.89 T 29-03-2018 IPR022887 Cell division suppressor protein, YneA CXR48_RS10790 9f9257ed8d6f3ddc4eca859e4edba138 233 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 233 1.1E-112 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CXR48_RS10790 9f9257ed8d6f3ddc4eca859e4edba138 233 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 35.699 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CXR48_RS10790 9f9257ed8d6f3ddc4eca859e4edba138 233 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CXR48_RS10790 9f9257ed8d6f3ddc4eca859e4edba138 233 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CXR48_RS10790 9f9257ed8d6f3ddc4eca859e4edba138 233 SUPERFAMILY SSF53335 4 227 5.02E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS10790 9f9257ed8d6f3ddc4eca859e4edba138 233 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 1.3E-136 T 29-03-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CXR48_RS10790 9f9257ed8d6f3ddc4eca859e4edba138 233 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 6.9E-80 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CXR48_RS10790 9f9257ed8d6f3ddc4eca859e4edba138 233 Gene3D G3DSA:3.40.50.150 1 229 8.7E-42 T 29-03-2018 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 SUPERFAMILY SSF56634 12 535 8.24E-227 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 Pfam PF00199 Catalase 31 416 1.2E-180 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 361 369 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 Pfam PF06628 Catalase-related immune-responsive 446 510 1.1E-22 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 PIRSF PIRSF038927 1 683 0.0 T 29-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 SMART SM01060 31 419 4.4E-276 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 SUPERFAMILY SSF52317 541 681 3.24E-18 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 Pfam PF01965 DJ-1/PfpI family 543 651 1.5E-12 T 29-03-2018 IPR002818 DJ-1/PfpI CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 PRINTS PR00067 Catalase signature 44 67 3.0E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 PRINTS PR00067 Catalase signature 107 125 3.0E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 PRINTS PR00067 Catalase signature 348 374 3.0E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 PRINTS PR00067 Catalase signature 316 343 3.0E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 PRINTS PR00067 Catalase signature 128 145 3.0E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 PRINTS PR00067 Catalase signature 147 165 3.0E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 Gene3D G3DSA:3.40.50.880 539 683 4.5E-21 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 ProSitePatterns PS00438 Catalase proximal active site signature. 67 83 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18465 a16e808fad1889e7973e8b3f5847640c 683 Gene3D G3DSA:2.40.180.10 1 386 1.6E-169 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 607 7.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 648 7.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 PRINTS PR00344 Bacterial sensor protein C-terminal signature 611 629 7.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 PRINTS PR00344 Bacterial sensor protein C-terminal signature 579 593 7.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Gene3D G3DSA:3.40.50.2300 680 875 1.6E-34 T 29-03-2018 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 SMART SM00388 428 496 2.9E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 SMART SM00448 688 801 5.1E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Pfam PF00072 Response regulator receiver domain 690 801 7.9E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Gene3D G3DSA:1.10.287.130 418 490 4.1E-14 T 29-03-2018 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 SUPERFAMILY SSF55874 878 1009 1.96E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 SUPERFAMILY SSF52172 684 813 7.26E-35 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 SUPERFAMILY SSF47384 419 496 7.85E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Pfam PF07695 7TM diverse intracellular signalling 207 404 4.0E-9 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 543 650 3.0E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 915 1009 6.0E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Pfam PF06580 Histidine kinase 817 897 5.2E-21 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Gene3D G3DSA:2.60.120.260 30 216 5.2E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 SMART SM00387 542 651 5.5E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 SMART SM00387 907 1014 0.0069 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Pfam PF00512 His Kinase A (phospho-acceptor) domain 429 496 1.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Gene3D G3DSA:3.30.565.10 491 651 8.3E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 Gene3D G3DSA:3.30.565.10 876 1017 1.9E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03695 0218234279b7808baae254f3f89322a0 1029 SUPERFAMILY SSF55874 485 649 1.44E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 331 4.0E-34 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 334 175.365 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 SMART SM00382 52 183 4.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 SUPERFAMILY SSF52540 21 253 2.38E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 Gene3D G3DSA:1.10.8.60 185 255 6.4E-31 T 29-03-2018 CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 235 6.3E-119 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 327 8.2E-152 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 Gene3D G3DSA:3.40.50.300 19 182 4.2E-29 T 29-03-2018 CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 SUPERFAMILY SSF46785 257 331 3.81E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 Gene3D G3DSA:1.10.10.10 258 328 2.9E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12790 f48030b16ef740c3c2a295d34ff687de 334 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 2.3E-33 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 106 120 1.3E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 186 208 1.3E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 228 248 1.3E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 1.3E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 Gene3D G3DSA:3.40.50.720 195 428 2.7E-74 T 29-03-2018 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 SUPERFAMILY SSF53223 18 197 1.25E-67 T 29-03-2018 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 SMART SM00839 197 426 1.5E-93 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 195 426 3.3E-75 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 Gene3D G3DSA:3.40.50.10860 47 181 1.2E-51 T 29-03-2018 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 PIRSF PIRSF000185 11 428 2.7E-167 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 SUPERFAMILY SSF51735 195 427 2.02E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 114 127 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS17880 3a2a05960d2011ff3f4d55d378e71a25 428 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 49 177 3.8E-55 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 SMART SM00387 359 466 1.4E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 465 4.3E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 309 4.5E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 Gene3D G3DSA:3.30.565.10 308 466 1.7E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 SUPERFAMILY SSF55874 303 465 9.56E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 Gene3D G3DSA:1.10.287.130 236 307 8.5E-12 T 29-03-2018 CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 SUPERFAMILY SSF47384 230 313 3.73E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS09075 ad720e9d23fab517b7df63d8a778d6fd 466 SMART SM00388 245 313 3.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS14235 0e27f63f59374b5224692e2633f8a99d 371 Gene3D G3DSA:3.20.20.120 146 343 2.6E-61 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CXR48_RS14235 0e27f63f59374b5224692e2633f8a99d 371 Gene3D G3DSA:3.30.390.10 1 145 1.1E-35 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS14235 0e27f63f59374b5224692e2633f8a99d 371 Pfam PF13378 Enolase C-terminal domain-like 145 355 5.9E-51 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CXR48_RS14235 0e27f63f59374b5224692e2633f8a99d 371 SUPERFAMILY SSF54826 3 127 1.93E-34 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS14235 0e27f63f59374b5224692e2633f8a99d 371 SUPERFAMILY SSF51604 125 360 8.78E-76 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CXR48_RS14235 0e27f63f59374b5224692e2633f8a99d 371 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 2 360 46.65 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS14235 0e27f63f59374b5224692e2633f8a99d 371 SMART SM00922 143 235 4.8E-24 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CXR48_RS14235 0e27f63f59374b5224692e2633f8a99d 371 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 126 7.3E-14 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CXR48_RS14235 0e27f63f59374b5224692e2633f8a99d 371 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 334 2.1E-154 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 266 1.1E-18 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 442 450 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 SMART SM00382 89 267 8.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 SUPERFAMILY SSF54211 350 532 1.52E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 SUPERFAMILY SSF52540 56 204 7.04E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 SUPERFAMILY SSF52540 235 328 7.04E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 Gene3D G3DSA:3.30.230.10 329 552 2.0E-53 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 533 5.9E-291 T 29-03-2018 IPR014251 Sporulation protease LonB CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 Gene3D G3DSA:1.10.8.60 256 328 7.2E-12 T 29-03-2018 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 Gene3D G3DSA:3.40.50.300 47 255 6.1E-33 T 29-03-2018 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 343 534 4.3E-33 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 3.2E-32 T 29-03-2018 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 458 3.2E-32 T 29-03-2018 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 3.2E-32 T 29-03-2018 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 469 488 3.2E-32 T 29-03-2018 CXR48_RS13005 deb029eb992b376ebc31410c8e3e6beb 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 3.2E-32 T 29-03-2018 CXR48_RS16975 ae981ead9747e9febef70132bee8b75f 174 Pfam PF02525 Flavodoxin-like fold 2 167 1.5E-46 T 29-03-2018 IPR003680 Flavodoxin-like fold CXR48_RS16975 ae981ead9747e9febef70132bee8b75f 174 SUPERFAMILY SSF52218 2 172 1.8E-46 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS16975 ae981ead9747e9febef70132bee8b75f 174 Gene3D G3DSA:3.40.50.360 1 174 9.9E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS14860 fc771a55807e1f5a20177bec8d2be5c8 409 Pfam PF06018 CodY GAF-like domain 16 155 4.0E-7 T 29-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CXR48_RS14860 fc771a55807e1f5a20177bec8d2be5c8 409 Pfam PF13556 PucR C-terminal helix-turn-helix domain 347 403 4.7E-18 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CXR48_RS14860 fc771a55807e1f5a20177bec8d2be5c8 409 Gene3D G3DSA:1.10.10.60 329 383 4.5E-11 T 29-03-2018 CXR48_RS14860 fc771a55807e1f5a20177bec8d2be5c8 409 Gene3D G3DSA:3.30.450.40 13 146 4.2E-11 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 2.6E-51 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 Gene3D G3DSA:2.40.110.10 121 217 4.1E-38 T 29-03-2018 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 SUPERFAMILY SSF56645 1 243 2.09E-84 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.9E-35 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 2.3E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 SUPERFAMILY SSF47203 229 380 1.48E-59 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 Gene3D G3DSA:1.20.140.10 218 380 3.2E-62 T 29-03-2018 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 PIRSF PIRSF016578 130 380 8.9E-20 T 29-03-2018 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 PIRSF PIRSF016578 2 111 4.9E-8 T 29-03-2018 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 Gene3D G3DSA:1.10.540.10 1 120 6.3E-37 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CXR48_RS09215 01753fe291c085bd89f2bbeaf158abfb 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 Gene3D G3DSA:2.30.24.10 2 43 4.5E-19 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 SUPERFAMILY SSF63520 169 272 4.71E-30 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 SMART SM01061 1 59 4.3E-22 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 Gene3D G3DSA:1.10.1790.10 44 161 8.5E-28 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 Gene3D G3DSA:1.10.1790.10 162 274 4.3E-27 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 SUPERFAMILY SSF63520 51 161 3.66E-32 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 Pfam PF03123 CAT RNA binding domain 2 55 6.7E-20 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 SUPERFAMILY SSF50151 2 53 6.67E-16 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 Pfam PF00874 PRD domain 72 159 5.2E-27 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18010 dd3f87dafeb858753c80de8c139b2805 276 Pfam PF00874 PRD domain 178 270 2.8E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SMART SM00823 Phosphopantetheine attachment site 2164 2234 6.1E-11 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SMART SM00823 Phosphopantetheine attachment site 289 360 0.0023 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SMART SM00823 Phosphopantetheine attachment site 3384 3455 0.0086 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 ProSitePatterns PS00012 Phosphopantetheine attachment site. 315 330 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2435 2451 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF53901 2284 2640 8.2E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF53901 2681 2700 8.2E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF51735 1501 1719 2.27E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:3.10.129.10 996 1120 5.0E-23 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:3.10.129.10 2 113 2.5E-6 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:3.40.50.720 1496 1746 9.1E-29 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:3.40.50.720 3108 3368 1.3E-38 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF08659 KR domain 1503 1681 1.5E-37 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF08659 KR domain 3116 3295 3.8E-45 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SMART SM01294 290 356 1.6E-5 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:3.40.47.10 2281 2534 8.0E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF08242 Methyltransferase domain 1939 2043 7.4E-18 T 29-03-2018 IPR013217 Methyltransferase type 12 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:3.40.47.10 2537 2703 1.4E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:3.40.47.10 656 826 4.0E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF47336 2164 2235 1.83E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF51735 3114 3341 1.07E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF51735 1296 1489 1.94E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SMART SM00826 993 1157 2.0E-19 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:1.10.1200.10 3376 3493 9.8E-11 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:1.10.1200.10 2157 2280 1.2E-14 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1503 1683 1.2E-22 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3116 3297 1.5E-34 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF47336 284 403 3.01E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:3.40.47.10 382 652 1.3E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2288 2522 5.2E-81 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 391 641 1.9E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2190 2205 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF53901 387 757 1.88E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF00550 Phosphopantetheine attachment site 2165 2230 5.6E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF00550 Phosphopantetheine attachment site 292 356 5.9E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF00550 Phosphopantetheine attachment site 3386 3450 1.9E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF53335 1902 2098 9.27E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2651 2762 1.3E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 770 890 2.3E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2530 2647 6.6E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 649 765 1.8E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:3.40.50.150 1836 2107 4.7E-22 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SUPERFAMILY SSF47336 3381 3455 1.44E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Gene3D G3DSA:1.10.1200.10 264 370 6.8E-15 T 29-03-2018 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SMART SM00825 Beta-ketoacyl synthase 2290 2705 1.5E-187 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 SMART SM00825 Beta-ketoacyl synthase 392 828 7.6E-203 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF14765 Polyketide synthase dehydratase 993 1279 5.4E-64 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08570 456d564ec1be1a82f7283a55f1cbfb9e 3514 Pfam PF14765 Polyketide synthase dehydratase 11 265 2.3E-20 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09015 1413c48a13b991b2290bbe365e51111b 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 131 2.0E-37 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS09015 1413c48a13b991b2290bbe365e51111b 339 SUPERFAMILY SSF50129 1 171 4.87E-51 T 29-03-2018 IPR011032 GroES-like CXR48_RS09015 1413c48a13b991b2290bbe365e51111b 339 Gene3D G3DSA:3.40.50.10730 156 304 3.3E-29 T 29-03-2018 CXR48_RS09015 1413c48a13b991b2290bbe365e51111b 339 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CXR48_RS09015 1413c48a13b991b2290bbe365e51111b 339 Pfam PF00107 Zinc-binding dehydrogenase 172 297 4.5E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS09015 1413c48a13b991b2290bbe365e51111b 339 SUPERFAMILY SSF51735 135 302 1.91E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS09015 1413c48a13b991b2290bbe365e51111b 339 SMART SM00829 8 336 3.5E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS09015 1413c48a13b991b2290bbe365e51111b 339 Gene3D G3DSA:3.90.180.10 1 155 6.0E-50 T 29-03-2018 CXR48_RS04075 1505439f8e850f1a266f43212f1eaac1 160 Pfam PF01047 MarR family 48 105 1.0E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS04075 1505439f8e850f1a266f43212f1eaac1 160 Gene3D G3DSA:1.10.10.10 29 144 1.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04075 1505439f8e850f1a266f43212f1eaac1 160 SUPERFAMILY SSF46785 24 155 9.97E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04075 1505439f8e850f1a266f43212f1eaac1 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 1.5E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS04075 1505439f8e850f1a266f43212f1eaac1 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 1.5E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS04075 1505439f8e850f1a266f43212f1eaac1 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 1.5E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS04075 1505439f8e850f1a266f43212f1eaac1 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 1.5E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS04075 1505439f8e850f1a266f43212f1eaac1 160 SMART SM00347 40 140 9.5E-34 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 Pfam PF01556 DnaJ C terminal domain 118 335 7.7E-44 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 371 41.48 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 Gene3D G3DSA:2.60.260.20 112 183 3.1E-13 T 29-03-2018 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 Gene3D G3DSA:2.60.260.20 257 367 6.4E-31 T 29-03-2018 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 SUPERFAMILY SSF49493 260 346 4.06E-26 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 SUPERFAMILY SSF49493 112 153 1.23E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 SUPERFAMILY SSF49493 216 259 1.23E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 Gene3D G3DSA:1.10.287.110 1 111 1.9E-37 T 29-03-2018 IPR001623 DnaJ domain CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 Pfam PF00226 DnaJ domain 5 66 6.5E-27 T 29-03-2018 IPR001623 DnaJ domain CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 351 8.0E-141 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 SUPERFAMILY SSF57938 132 213 7.85E-18 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 PRINTS PR00625 DnaJ domain signature 25 40 7.6E-32 T 29-03-2018 IPR001623 DnaJ domain CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 PRINTS PR00625 DnaJ domain signature 41 61 7.6E-32 T 29-03-2018 IPR001623 DnaJ domain CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 PRINTS PR00625 DnaJ domain signature 7 25 7.6E-32 T 29-03-2018 IPR001623 DnaJ domain CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 PRINTS PR00625 DnaJ domain signature 61 80 7.6E-32 T 29-03-2018 IPR001623 DnaJ domain CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 Pfam PF00684 DnaJ central domain 145 209 1.4E-13 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 SUPERFAMILY SSF46565 1 101 4.58E-37 T 29-03-2018 IPR001623 DnaJ domain CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 29-03-2018 IPR018253 DnaJ domain, conserved site CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 Gene3D G3DSA:2.60.260.20 184 256 1.4E-19 T 29-03-2018 CXR48_RS12230 b53af8bb6b41cf4266de726e693a3033 375 SMART SM00271 4 61 4.0E-30 T 29-03-2018 IPR001623 DnaJ domain CXR48_RS06455 74791773dd079e68bcc859aa7324926c 365 Pfam PF13378 Enolase C-terminal domain-like 144 355 1.0E-51 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CXR48_RS06455 74791773dd079e68bcc859aa7324926c 365 SUPERFAMILY SSF54826 2 125 1.03E-31 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS06455 74791773dd079e68bcc859aa7324926c 365 SMART SM00922 141 240 1.9E-29 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CXR48_RS06455 74791773dd079e68bcc859aa7324926c 365 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 12 124 8.3E-21 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CXR48_RS06455 74791773dd079e68bcc859aa7324926c 365 SUPERFAMILY SSF51604 112 355 6.55E-69 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CXR48_RS06455 74791773dd079e68bcc859aa7324926c 365 Gene3D G3DSA:3.20.20.120 136 353 2.9E-64 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CXR48_RS06455 74791773dd079e68bcc859aa7324926c 365 Gene3D G3DSA:3.30.390.10 1 135 2.2E-34 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 Gene3D G3DSA:2.30.42.10 106 186 6.3E-20 T 29-03-2018 CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 Pfam PF03572 Peptidase family S41 200 361 5.7E-49 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 Gene3D G3DSA:1.10.101.10 371 449 6.8E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 SMART SM00228 98 169 6.1E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 Gene3D G3DSA:3.90.226.10 187 370 7.6E-55 T 29-03-2018 CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 SMART SM00245 171 362 1.0E-79 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 Gene3D G3DSA:3.30.750.44 30 105 2.3E-18 T 29-03-2018 CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 Pfam PF13180 PDZ domain 99 175 3.8E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 SUPERFAMILY SSF50156 69 189 2.37E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 SUPERFAMILY SSF52096 193 366 3.15E-69 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 SUPERFAMILY SSF52096 37 116 3.15E-69 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 Pfam PF01471 Putative peptidoglycan binding domain 384 439 2.4E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 SUPERFAMILY SSF47090 371 445 1.57E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS16585 919408f8049fffd08265772fb47d3574 466 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 50 368 4.3E-130 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CXR48_RS03845 574de699ebbc3c1bc943b2bccca5729c 171 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 170 1.7E-58 T 29-03-2018 IPR006286 Peptidase C56, PfpI CXR48_RS03845 574de699ebbc3c1bc943b2bccca5729c 171 Pfam PF01965 DJ-1/PfpI family 3 168 1.1E-56 T 29-03-2018 IPR002818 DJ-1/PfpI CXR48_RS03845 574de699ebbc3c1bc943b2bccca5729c 171 SUPERFAMILY SSF52317 1 170 2.29E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS03845 574de699ebbc3c1bc943b2bccca5729c 171 Gene3D G3DSA:3.40.50.880 1 171 3.3E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 Pfam PF01842 ACT domain 452 513 2.6E-9 T 29-03-2018 IPR002912 ACT domain CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 Gene3D G3DSA:3.30.1330.90 314 446 7.6E-33 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 Gene3D G3DSA:3.40.50.720 1 104 1.9E-30 T 29-03-2018 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 SUPERFAMILY SSF143548 316 446 6.28E-34 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 310 5.3E-34 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 524 5.5E-225 T 29-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 Gene3D G3DSA:3.40.50.720 105 280 1.0E-58 T 29-03-2018 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 SUPERFAMILY SSF51735 95 279 4.96E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 SUPERFAMILY SSF55021 440 522 5.0E-18 T 29-03-2018 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 Gene3D G3DSA:3.30.70.260 447 522 2.7E-17 T 29-03-2018 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 141 168 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 278 6.7E-61 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CXR48_RS10940 44b60cc95fcd829398d02146829ace95 525 SUPERFAMILY SSF52283 14 126 4.73E-33 T 29-03-2018 CXR48_RS15800 a18779218000aee42f3797f551ab4d77 179 SUPERFAMILY SSF55729 1 152 5.49E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS15800 a18779218000aee42f3797f551ab4d77 179 Gene3D G3DSA:3.40.630.30 5 167 8.2E-21 T 29-03-2018 CXR48_RS15800 a18779218000aee42f3797f551ab4d77 179 Pfam PF00583 Acetyltransferase (GNAT) family 33 142 2.0E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS03735 75ef339e0fe0df7c615f3b80c9ccd1f1 264 SUPERFAMILY SSF56281 17 254 1.44E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS03735 75ef339e0fe0df7c615f3b80c9ccd1f1 264 Gene3D G3DSA:3.60.15.10 11 262 2.4E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS03735 75ef339e0fe0df7c615f3b80c9ccd1f1 264 SMART SM00849 30 240 1.0E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS03735 75ef339e0fe0df7c615f3b80c9ccd1f1 264 Pfam PF00753 Metallo-beta-lactamase superfamily 28 240 2.5E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 8.3E-33 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 SUPERFAMILY SSF50249 2 125 5.83E-51 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 SMART SM01382 124 253 3.0E-92 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 Gene3D G3DSA:2.40.50.140 1 114 6.1E-49 T 29-03-2018 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 Gene3D G3DSA:2.30.30.30 119 195 3.8E-34 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 PIRSF PIRSF002158 3 276 6.6E-99 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 SMART SM01383 42 118 7.8E-45 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 Gene3D G3DSA:4.10.950.10 197 275 1.0E-34 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 4.1E-141 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 4.5E-57 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 49.764 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00750 059205cfeae83aba168bdd4fb5a3b074 277 SUPERFAMILY SSF50104 126 273 5.54E-61 T 29-03-2018 IPR008991 Translation protein SH3-like domain CXR48_RS13340 9548e0749f644f2d322861648e615a47 183 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 18 87 6.3E-32 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CXR48_RS13340 9548e0749f644f2d322861648e615a47 183 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 12 181 31.09 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CXR48_RS13340 9548e0749f644f2d322861648e615a47 183 Gene3D G3DSA:3.30.110.10 90 183 2.2E-36 T 29-03-2018 CXR48_RS13340 9548e0749f644f2d322861648e615a47 183 SUPERFAMILY SSF54364 16 89 3.92E-29 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CXR48_RS13340 9548e0749f644f2d322861648e615a47 183 SUPERFAMILY SSF55200 93 182 1.96E-33 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CXR48_RS13340 9548e0749f644f2d322861648e615a47 183 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 18 180 6.4E-78 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CXR48_RS13340 9548e0749f644f2d322861648e615a47 183 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 94 179 3.2E-38 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CXR48_RS13340 9548e0749f644f2d322861648e615a47 183 Gene3D G3DSA:3.10.20.80 13 89 1.2E-32 T 29-03-2018 CXR48_RS13340 9548e0749f644f2d322861648e615a47 183 ProSitePatterns PS00938 Initiation factor 3 signature. 69 82 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Gene3D G3DSA:3.30.1490.20 129 201 3.0E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 SUPERFAMILY SSF52440 1 113 3.53E-51 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 SUPERFAMILY SSF56059 83 351 1.22E-71 T 29-03-2018 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.2E-47 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Gene3D G3DSA:3.40.50.20 1 128 1.0E-53 T 29-03-2018 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 1.1E-82 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Gene3D G3DSA:3.30.470.20 204 445 2.6E-102 T 29-03-2018 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 1.7E-43 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 SUPERFAMILY SSF51246 332 445 3.61E-47 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 449 1.3E-247 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CXR48_RS11690 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 SMART SM00878 337 443 3.0E-70 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS16190 2add11da600ed2d5a7060897a8215be3 379 Pfam PF00534 Glycosyl transferases group 1 185 350 4.6E-43 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CXR48_RS16190 2add11da600ed2d5a7060897a8215be3 379 Gene3D G3DSA:3.40.50.2000 20 182 2.0E-17 T 29-03-2018 CXR48_RS16190 2add11da600ed2d5a7060897a8215be3 379 SUPERFAMILY SSF53756 19 368 6.28E-77 T 29-03-2018 CXR48_RS16190 2add11da600ed2d5a7060897a8215be3 379 Pfam PF13477 Glycosyl transferase 4-like 4 146 2.4E-16 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CXR48_RS16190 2add11da600ed2d5a7060897a8215be3 379 Gene3D G3DSA:3.40.50.2000 183 352 3.6E-47 T 29-03-2018 CXR48_RS10960 65ff41a15f583a9c2abf85e10ac68ff8 240 Pfam PF00072 Response regulator receiver domain 9 117 3.5E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS10960 65ff41a15f583a9c2abf85e10ac68ff8 240 Gene3D G3DSA:3.40.50.2300 1 131 8.8E-41 T 29-03-2018 CXR48_RS10960 65ff41a15f583a9c2abf85e10ac68ff8 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 235 1.3E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS10960 65ff41a15f583a9c2abf85e10ac68ff8 240 SUPERFAMILY SSF52172 6 193 2.7E-44 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS10960 65ff41a15f583a9c2abf85e10ac68ff8 240 SMART SM00862 158 235 7.4E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS10960 65ff41a15f583a9c2abf85e10ac68ff8 240 Gene3D G3DSA:1.10.10.10 132 240 4.4E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10960 65ff41a15f583a9c2abf85e10ac68ff8 240 SMART SM00448 7 117 1.6E-47 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SUPERFAMILY SSF54106 301 344 2.22E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Gene3D G3DSA:3.90.1720.10 363 484 7.7E-35 T 29-03-2018 CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SUPERFAMILY SSF54106 233 276 2.88E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Pfam PF00877 NlpC/P60 family 381 481 6.5E-29 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SMART SM00257 28 71 9.3E-17 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SMART SM00257 234 277 5.9E-18 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SMART SM00257 302 345 6.6E-18 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SMART SM00257 166 209 1.2E-13 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SMART SM00257 93 136 1.3E-16 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Gene3D G3DSA:3.10.350.10 295 360 9.0E-18 T 29-03-2018 CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Gene3D G3DSA:3.10.350.10 228 294 6.3E-19 T 29-03-2018 CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Gene3D G3DSA:3.10.350.10 21 85 5.9E-15 T 29-03-2018 CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SUPERFAMILY SSF54001 365 483 2.35E-36 T 29-03-2018 CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SUPERFAMILY SSF54106 166 207 1.03E-8 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Pfam PF01476 LysM domain 30 71 2.2E-14 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Pfam PF01476 LysM domain 167 207 6.5E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Pfam PF01476 LysM domain 235 276 3.1E-16 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Pfam PF01476 LysM domain 94 135 3.6E-14 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Pfam PF01476 LysM domain 303 344 2.1E-15 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Gene3D G3DSA:3.10.350.10 154 227 8.4E-13 T 29-03-2018 CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 Gene3D G3DSA:3.10.350.10 86 153 2.6E-16 T 29-03-2018 CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SUPERFAMILY SSF54106 93 135 3.92E-11 T 29-03-2018 IPR018392 LysM domain CXR48_RS04670 ba799904be0453701947edf1d38ba25b 484 SUPERFAMILY SSF54106 27 71 4.58E-10 T 29-03-2018 IPR018392 LysM domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 625 728 1.3E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SUPERFAMILY SSF55785 138 260 2.27E-14 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 151 268 9.0E-10 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 390 509 2.5E-8 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 272 389 1.2E-11 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 31 147 1.4E-7 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SUPERFAMILY SSF55785 379 451 1.77E-13 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Pfam PF13426 PAS domain 164 261 0.002 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SUPERFAMILY SSF55785 20 139 8.86E-14 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Gene3D G3DSA:3.30.565.10 582 739 1.5E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SUPERFAMILY SSF47384 512 579 5.89E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Pfam PF13188 PAS domain 395 447 3.9E-4 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Gene3D G3DSA:3.30.450.20 370 507 1.4E-16 T 29-03-2018 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Gene3D G3DSA:3.30.450.20 149 266 6.5E-19 T 29-03-2018 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SMART SM00387 623 730 1.1E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 661 675 3.6E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 690 708 3.6E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 714 727 3.6E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 679 689 3.6E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Gene3D G3DSA:3.30.450.20 16 148 1.2E-15 T 29-03-2018 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Pfam PF00512 His Kinase A (phospho-acceptor) domain 519 579 5.5E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SUPERFAMILY SSF55874 576 729 1.57E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SUPERFAMILY SSF55785 259 371 6.63E-16 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SMART SM00091 394 462 0.05 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SMART SM00091 153 219 0.006 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SMART SM00091 32 98 7.9E-5 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SMART SM00091 274 342 2.3E-7 T 29-03-2018 IPR000014 PAS domain CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 SMART SM00388 517 581 1.1E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Gene3D G3DSA:3.30.450.20 267 369 3.5E-18 T 29-03-2018 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Pfam PF00989 PAS fold 274 371 8.3E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Pfam PF00989 PAS fold 33 138 9.4E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS06705 f640ad8c1fceb2c572df4b485abe42fa 739 Gene3D G3DSA:1.10.287.130 508 577 2.9E-12 T 29-03-2018 CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 SUPERFAMILY SSF46785 1 82 3.27E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 Gene3D G3DSA:3.40.190.10 174 259 2.3E-16 T 29-03-2018 CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 Gene3D G3DSA:1.10.10.10 1 83 2.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 Pfam PF03466 LysR substrate binding domain 90 283 1.8E-27 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 SUPERFAMILY SSF53850 89 287 1.69E-27 T 29-03-2018 CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 5.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS15390 4c3b8663aa270b971227962fd4fe926b 295 Gene3D G3DSA:3.40.190.10 87 173 1.6E-9 T 29-03-2018 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 SUPERFAMILY SSF53223 5 273 7.91E-102 T 29-03-2018 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 Gene3D G3DSA:3.40.50.10380 16 271 4.9E-102 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 SMART SM01274 82 264 2.7E-92 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 SMART SM00919 274 534 2.8E-117 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 Gene3D G3DSA:3.40.50.720 272 564 1.8E-103 T 29-03-2018 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 Pfam PF03949 Malic enzyme, NAD binding domain 274 534 6.6E-102 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 PIRSF PIRSF000106 2 565 5.7E-227 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 Pfam PF00390 Malic enzyme, N-terminal domain 82 264 1.3E-72 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 PRINTS PR00072 Malic enzyme signature 88 112 5.3E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 PRINTS PR00072 Malic enzyme signature 270 286 5.3E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 PRINTS PR00072 Malic enzyme signature 186 208 5.3E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 PRINTS PR00072 Malic enzyme signature 150 179 5.3E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 PRINTS PR00072 Malic enzyme signature 245 263 5.3E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 PRINTS PR00072 Malic enzyme signature 301 317 5.3E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 PRINTS PR00072 Malic enzyme signature 412 428 5.3E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 SUPERFAMILY SSF51735 274 562 2.89E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS17520 88fd87409ebc14fc5f5bc4810ae0b977 565 ProSitePatterns PS00331 Malic enzymes signature. 270 286 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CXR48_RS14915 94f53789c859ae57cc6ced4adb2fb90e 197 Pfam PF02632 BioY family 38 183 3.3E-29 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CXR48_RS14915 94f53789c859ae57cc6ced4adb2fb90e 197 PIRSF PIRSF016661 1 192 1.6E-42 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CXR48_RS18550 7f27fe553ddd1f78e3953ec226587688 148 Pfam PF00582 Universal stress protein family 1 148 4.4E-33 T 29-03-2018 IPR006016 UspA GO:0006950 CXR48_RS18550 7f27fe553ddd1f78e3953ec226587688 148 SUPERFAMILY SSF52402 2 148 3.27E-39 T 29-03-2018 CXR48_RS18550 7f27fe553ddd1f78e3953ec226587688 148 PIRSF PIRSF006276 1 148 8.2E-18 T 29-03-2018 IPR006015 Universal stress protein A CXR48_RS18550 7f27fe553ddd1f78e3953ec226587688 148 Gene3D G3DSA:3.40.50.620 1 148 5.1E-40 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS18550 7f27fe553ddd1f78e3953ec226587688 148 PRINTS PR01438 Universal stress protein signature 108 120 2.5E-21 T 29-03-2018 IPR006015 Universal stress protein A CXR48_RS18550 7f27fe553ddd1f78e3953ec226587688 148 PRINTS PR01438 Universal stress protein signature 126 148 2.5E-21 T 29-03-2018 IPR006015 Universal stress protein A CXR48_RS18550 7f27fe553ddd1f78e3953ec226587688 148 PRINTS PR01438 Universal stress protein signature 2 20 2.5E-21 T 29-03-2018 IPR006015 Universal stress protein A CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1166 1351 8.8E-38 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2686 2867 1.3E-55 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM00823 Phosphopantetheine attachment site 1435 1505 1.2E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM00823 Phosphopantetheine attachment site 2950 3021 0.014 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM00823 Phosphopantetheine attachment site 3046 3117 2.7E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM01294 3047 3113 4.0E-5 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF00550 Phosphopantetheine attachment site 2952 3017 3.8E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF00550 Phosphopantetheine attachment site 1438 1501 5.0E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF00550 Phosphopantetheine attachment site 3049 3113 6.3E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF53901 1546 1916 2.65E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF53901 1960 1980 2.65E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF47336 2948 3022 1.05E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 168 184 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 380 7.4E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1806 1923 3.7E-39 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3420 3544 6.8E-37 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF47336 3164 3176 3.01E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF47336 3041 3118 3.01E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2976 2991 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.10.129.10 3780 3898 1.0E-10 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.10.129.10 2148 2284 7.9E-18 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1959 2024 7.6E-10 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 384 484 2.4E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3548 3638 1.0E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.40.50.720 2682 2887 1.2E-46 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.40.47.10 3156 3423 2.0E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF08659 KR domain 2686 2866 1.0E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF08659 KR domain 1167 1350 3.5E-52 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF53901 8 378 1.52E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:1.10.1200.10 2943 3026 9.2E-9 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.40.47.10 1813 1982 3.9E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.40.47.10 270 432 1.1E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.40.47.10 3427 3601 3.6E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM00826 2166 2322 9.1E-6 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3072 3087 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF47336 1436 1560 1.18E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.40.47.10 1 267 2.2E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.40.47.10 1543 1810 1.4E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:1.10.1200.10 1432 1542 7.6E-10 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 173 191 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3325 3341 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF53901 3579 3599 2.18E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF53901 3160 3537 2.18E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:3.40.50.720 1160 1423 1.3E-37 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1711 1727 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF51735 2684 2914 7.4E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Gene3D G3DSA:1.10.1200.10 3031 3118 7.8E-14 T 29-03-2018 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1548 1798 1.1E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 255 3.5E-83 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3164 3412 6.1E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM00825 Beta-ketoacyl synthase 1548 1984 3.7E-187 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM00825 Beta-ketoacyl synthase 3166 3603 9.3E-198 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SMART SM00825 Beta-ketoacyl synthase 11 434 5.2E-194 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 SUPERFAMILY SSF51735 1164 1390 4.71E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF14765 Polyketide synthase dehydratase 2173 2440 5.0E-48 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07225 34e174ec2b4baddfeb8f7335c50eac01 4083 Pfam PF14765 Polyketide synthase dehydratase 3777 4048 2.7E-41 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS10420 a020bb202f32a607c3d68f50e66ebe4f 65 Gene3D G3DSA:3.30.40.30 3 65 1.4E-26 T 29-03-2018 CXR48_RS10420 a020bb202f32a607c3d68f50e66ebe4f 65 SUPERFAMILY SSF160713 2 64 1.96E-20 T 29-03-2018 IPR023118 YqaI domain CXR48_RS10420 a020bb202f32a607c3d68f50e66ebe4f 65 Pfam PF09466 Hypothetical protein Yqai 3 64 8.3E-21 T 29-03-2018 IPR018474 Uncharacterised protein family YqaI CXR48_RS05005 19580395a930b8a98fc504be24c99036 359 PIRSF PIRSF000525 1 359 1.7E-149 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CXR48_RS05005 19580395a930b8a98fc504be24c99036 359 Gene3D G3DSA:3.90.1150.10 256 357 9.4E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS05005 19580395a930b8a98fc504be24c99036 359 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 185 204 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CXR48_RS05005 19580395a930b8a98fc504be24c99036 359 Gene3D G3DSA:3.40.640.10 16 255 2.0E-25 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS05005 19580395a930b8a98fc504be24c99036 359 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 357 3.7E-153 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CXR48_RS05005 19580395a930b8a98fc504be24c99036 359 SUPERFAMILY SSF53383 1 357 5.63E-109 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS05005 19580395a930b8a98fc504be24c99036 359 Pfam PF00266 Aminotransferase class-V 6 347 1.4E-49 T 29-03-2018 IPR000192 Aminotransferase class V domain CXR48_RS05005 19580395a930b8a98fc504be24c99036 359 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 358 47.617 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CXR48_RS08750 c4ecf4b76d76c29eb78761dc53d69799 865 Gene3D G3DSA:3.50.30.10 764 865 2.1E-31 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS08750 c4ecf4b76d76c29eb78761dc53d69799 865 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 317 5.6E-96 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CXR48_RS08750 c4ecf4b76d76c29eb78761dc53d69799 865 Gene3D G3DSA:3.30.470.20 184 314 3.5E-44 T 29-03-2018 CXR48_RS08750 c4ecf4b76d76c29eb78761dc53d69799 865 Gene3D G3DSA:3.30.1490.20 1 183 1.5E-56 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS08750 c4ecf4b76d76c29eb78761dc53d69799 865 SUPERFAMILY SSF52009 759 862 7.06E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS08750 c4ecf4b76d76c29eb78761dc53d69799 865 Pfam PF00391 PEP-utilising enzyme, mobile domain 789 860 9.4E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS08750 c4ecf4b76d76c29eb78761dc53d69799 865 SUPERFAMILY SSF56059 1 342 5.18E-98 T 29-03-2018 CXR48_RS08750 c4ecf4b76d76c29eb78761dc53d69799 865 Gene3D G3DSA:1.10.150.20 685 763 0.019 T 29-03-2018 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 Gene3D G3DSA:3.30.70.270 122 174 1.7E-14 T 29-03-2018 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 Gene3D G3DSA:3.30.70.270 46 121 1.3E-26 T 29-03-2018 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 Pfam PF00817 impB/mucB/samB family 11 158 7.6E-52 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 Gene3D G3DSA:1.10.150.20 175 249 6.9E-21 T 29-03-2018 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 PIRSF PIRSF036603 1 139 2.0E-27 T 29-03-2018 IPR017061 DNA polymerase eta/kappa/iota/IV KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 PIRSF PIRSF036603 123 414 1.2E-17 T 29-03-2018 IPR017061 DNA polymerase eta/kappa/iota/IV KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 Hamap MF_01113 DNA polymerase IV [dinB]. 5 357 38.331 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 Pfam PF11798 IMS family HHH motif 172 201 4.0E-8 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 SUPERFAMILY SSF56672 5 238 1.42E-83 T 29-03-2018 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 Pfam PF11799 impB/mucB/samB family C-terminal domain 247 350 8.8E-18 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 Gene3D G3DSA:3.30.1490.100 250 360 1.2E-27 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS11445 5753a3abf3674eb1e47a06514b90179d 414 SUPERFAMILY SSF100879 247 357 9.22E-25 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 Pfam PF01225 Mur ligase family, catalytic domain 31 100 6.0E-9 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 Pfam PF08245 Mur ligase middle domain 111 292 3.6E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 Gene3D G3DSA:3.40.1190.10 96 309 1.4E-59 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 452 6.6E-140 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 Gene3D G3DSA:3.90.190.20 312 456 3.6E-43 T 29-03-2018 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 SUPERFAMILY SSF53623 107 310 1.57E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 Gene3D G3DSA:3.40.1390.10 1 95 4.3E-25 T 29-03-2018 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 453 34.478 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 392 5.1E-17 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 SUPERFAMILY SSF63418 3 102 2.09E-22 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CXR48_RS02385 77ecd0cf6551dcba841bdf48f664b8b7 456 SUPERFAMILY SSF53244 314 452 1.43E-35 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 SUPERFAMILY SSF52374 21 181 2.04E-27 T 29-03-2018 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 86 9.1E-11 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 PIRSF PIRSF004491 3 313 4.0E-108 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 312 1.6E-114 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 Pfam PF01687 Riboflavin kinase 186 310 5.3E-38 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 SUPERFAMILY SSF82114 175 312 1.66E-46 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 SMART SM00904 185 312 1.2E-62 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 Gene3D G3DSA:2.40.30.30 182 313 4.8E-42 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 Pfam PF06574 FAD synthetase 14 168 1.8E-47 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CXR48_RS08315 c8aeaa5f76c8f4b5ef8822e81620afcd 313 Gene3D G3DSA:3.40.50.620 1 181 2.5E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS04015 9c59134557978cd83157638540b61265 605 SUPERFAMILY SSF90123 32 349 3.92E-87 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04015 9c59134557978cd83157638540b61265 605 Pfam PF00005 ABC transporter 382 531 8.1E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS04015 9c59134557978cd83157638540b61265 605 SUPERFAMILY SSF52540 356 602 2.01E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04015 9c59134557978cd83157638540b61265 605 Pfam PF00664 ABC transporter transmembrane region 49 320 5.2E-64 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04015 9c59134557978cd83157638540b61265 605 SMART SM00382 391 577 8.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04015 9c59134557978cd83157638540b61265 605 Gene3D G3DSA:3.40.50.300 352 605 7.7E-77 T 29-03-2018 CXR48_RS04015 9c59134557978cd83157638540b61265 605 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS04015 9c59134557978cd83157638540b61265 605 Gene3D G3DSA:1.20.1560.10 16 351 4.9E-87 T 29-03-2018 CXR48_RS04615 9f9536b26fce4a6a4bb3e1cd7cbb840c 450 Pfam PF00202 Aminotransferase class-III 34 443 8.6E-108 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS04615 9f9536b26fce4a6a4bb3e1cd7cbb840c 450 PIRSF PIRSF000521 32 143 2.7E-7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS04615 9f9536b26fce4a6a4bb3e1cd7cbb840c 450 PIRSF PIRSF000521 134 447 1.5E-25 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS04615 9f9536b26fce4a6a4bb3e1cd7cbb840c 450 SUPERFAMILY SSF53383 24 444 1.09E-124 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS04615 9f9536b26fce4a6a4bb3e1cd7cbb840c 450 Gene3D G3DSA:3.90.1150.10 2 181 3.5E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS04615 9f9536b26fce4a6a4bb3e1cd7cbb840c 450 Gene3D G3DSA:3.90.1150.10 327 448 1.8E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS04615 9f9536b26fce4a6a4bb3e1cd7cbb840c 450 Gene3D G3DSA:3.40.640.10 191 326 3.5E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS04615 9f9536b26fce4a6a4bb3e1cd7cbb840c 450 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 457 1.5E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 SMART SM00388 236 301 3.0E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 SUPERFAMILY SSF55874 292 456 1.7E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 PRINTS PR01780 Lantibiotic regulatory protein signature 208 222 5.6E-11 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 PRINTS PR01780 Lantibiotic regulatory protein signature 73 88 5.6E-11 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 PRINTS PR01780 Lantibiotic regulatory protein signature 386 402 5.6E-11 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 PRINTS PR01780 Lantibiotic regulatory protein signature 407 422 5.6E-11 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 PRINTS PR01780 Lantibiotic regulatory protein signature 245 261 5.6E-11 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 Gene3D G3DSA:3.30.565.10 304 466 8.0E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 SUPERFAMILY SSF47384 221 299 2.16E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 Gene3D G3DSA:1.10.287.130 219 297 2.2E-9 T 29-03-2018 CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 SMART SM00387 347 458 2.2E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15865 2f1e834779b2a65611c9c0977f72026e 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 300 3.8E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2117 2132 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 677 693 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SUPERFAMILY SSF47336 1373 1449 1.96E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Gene3D G3DSA:3.40.50.1820 2175 2457 1.1E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 771 888 5.4E-34 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1729 1843 1.5E-34 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF00975 Thioesterase domain 2182 2456 6.0E-43 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SMART SM00825 Beta-ketoacyl synthase 515 948 9.5E-118 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SMART SM00825 Beta-ketoacyl synthase 1491 1905 1.3E-127 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Gene3D G3DSA:3.40.47.10 1486 1730 5.4E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1490 1719 1.5E-72 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 513 763 9.7E-67 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 892 1009 3.7E-8 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1855 1965 3.1E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF08242 Methyltransferase domain 165 269 6.3E-16 T 29-03-2018 IPR013217 Methyltransferase type 12 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Gene3D G3DSA:3.40.47.10 507 775 1.0E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Gene3D G3DSA:3.40.50.150 118 382 4.6E-25 T 29-03-2018 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SUPERFAMILY SSF47336 2094 2164 1.57E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SUPERFAMILY SSF53901 510 881 1.97E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SUPERFAMILY SSF53901 924 942 1.97E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF14765 Polyketide synthase dehydratase 1095 1348 2.4E-27 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF00550 Phosphopantetheine attachment site 383 447 2.9E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF00550 Phosphopantetheine attachment site 1378 1442 5.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Pfam PF00550 Phosphopantetheine attachment site 2096 2153 2.0E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SMART SM00823 Phosphopantetheine attachment site 381 451 5.3E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SMART SM00823 Phosphopantetheine attachment site 2091 2139 0.049 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SMART SM00823 Phosphopantetheine attachment site 1376 1447 1.3E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SUPERFAMILY SSF53335 126 327 4.69E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SMART SM01294 382 447 2.2E-4 T 29-03-2018 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SUPERFAMILY SSF53474 2163 2444 3.08E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Gene3D G3DSA:3.40.47.10 1734 1903 4.1E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Gene3D G3DSA:3.40.47.10 779 946 7.9E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Gene3D G3DSA:1.10.1200.10 1370 1485 1.2E-11 T 29-03-2018 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Gene3D G3DSA:1.10.1200.10 383 506 6.0E-12 T 29-03-2018 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 Gene3D G3DSA:1.10.1200.10 2088 2174 5.4E-9 T 29-03-2018 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SUPERFAMILY SSF53901 1881 1901 5.47E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SUPERFAMILY SSF53901 1489 1842 5.47E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08580 c550ad1b3416e13f890deda20435c2f7 2485 SUPERFAMILY SSF47336 379 452 5.37E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08735 58966f7bc97f083cb3a16a72ff4b690b 384 SUPERFAMILY SSF53067 80 379 2.99E-59 T 29-03-2018 CXR48_RS08735 58966f7bc97f083cb3a16a72ff4b690b 384 ProSitePatterns PS01125 ROK family signature. 213 240 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CXR48_RS08735 58966f7bc97f083cb3a16a72ff4b690b 384 Gene3D G3DSA:1.10.10.10 13 64 4.8E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08735 58966f7bc97f083cb3a16a72ff4b690b 384 Gene3D G3DSA:3.30.420.40 199 384 3.9E-50 T 29-03-2018 CXR48_RS08735 58966f7bc97f083cb3a16a72ff4b690b 384 Pfam PF13412 Winged helix-turn-helix DNA-binding 14 56 7.2E-8 T 29-03-2018 CXR48_RS08735 58966f7bc97f083cb3a16a72ff4b690b 384 Gene3D G3DSA:3.30.420.40 72 198 9.2E-28 T 29-03-2018 CXR48_RS08735 58966f7bc97f083cb3a16a72ff4b690b 384 SUPERFAMILY SSF46785 8 74 1.36E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08735 58966f7bc97f083cb3a16a72ff4b690b 384 Pfam PF00480 ROK family 83 375 2.1E-95 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CXR48_RS05720 cd8ef69b6f57b9c9c84ef4d369a10a69 614 SUPERFAMILY SSF51735 403 516 3.43E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS05720 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Pfam PF02254 TrkA-N domain 406 514 1.8E-9 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CXR48_RS05720 cd8ef69b6f57b9c9c84ef4d369a10a69 614 SUPERFAMILY SSF116726 541 612 3.92E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS05720 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Gene3D G3DSA:3.40.50.720 395 535 4.7E-11 T 29-03-2018 CXR48_RS05720 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Pfam PF00999 Sodium/hydrogen exchanger family 10 392 1.7E-79 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CXR48_RS05720 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Gene3D G3DSA:1.20.91.10 241 325 9.2E-18 T 29-03-2018 CXR48_RS05720 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Pfam PF02080 TrkA-C domain 553 612 2.6E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS05720 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Gene3D G3DSA:3.30.70.1450 536 614 7.0E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS18405 8b13738bb06b3b288a6c3e576e3171e9 366 Pfam PF03459 TOBE domain 303 355 4.5E-8 T 29-03-2018 IPR005116 Transport-associated OB, type 1 CXR48_RS18405 8b13738bb06b3b288a6c3e576e3171e9 366 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS18405 8b13738bb06b3b288a6c3e576e3171e9 366 Gene3D G3DSA:2.40.50.140 294 349 4.6E-15 T 29-03-2018 CXR48_RS18405 8b13738bb06b3b288a6c3e576e3171e9 366 Gene3D G3DSA:2.40.50.100 240 293 3.0E-14 T 29-03-2018 CXR48_RS18405 8b13738bb06b3b288a6c3e576e3171e9 366 Gene3D G3DSA:3.40.50.300 1 235 3.7E-74 T 29-03-2018 CXR48_RS18405 8b13738bb06b3b288a6c3e576e3171e9 366 SUPERFAMILY SSF52540 4 243 6.89E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18405 8b13738bb06b3b288a6c3e576e3171e9 366 SMART SM00382 29 212 6.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS18405 8b13738bb06b3b288a6c3e576e3171e9 366 Pfam PF00005 ABC transporter 21 162 8.5E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS18405 8b13738bb06b3b288a6c3e576e3171e9 366 SUPERFAMILY SSF50331 237 364 2.67E-28 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CXR48_RS10805 f24564b871e8715c94a5c8a30c5dc2ed 190 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CXR48_RS10805 f24564b871e8715c94a5c8a30c5dc2ed 190 Pfam PF01227 GTP cyclohydrolase I 9 186 8.0E-82 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CXR48_RS10805 f24564b871e8715c94a5c8a30c5dc2ed 190 SUPERFAMILY SSF55620 3 187 7.26E-80 T 29-03-2018 CXR48_RS10805 f24564b871e8715c94a5c8a30c5dc2ed 190 Gene3D G3DSA:1.10.286.10 7 55 5.0E-27 T 29-03-2018 CXR48_RS10805 f24564b871e8715c94a5c8a30c5dc2ed 190 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 42.891 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CXR48_RS10805 f24564b871e8715c94a5c8a30c5dc2ed 190 Gene3D G3DSA:3.30.1130.10 56 189 6.1E-60 T 29-03-2018 CXR48_RS10805 f24564b871e8715c94a5c8a30c5dc2ed 190 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 188 5.7E-85 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CXR48_RS10805 f24564b871e8715c94a5c8a30c5dc2ed 190 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 SUPERFAMILY SSF57716 223 274 5.5E-17 T 29-03-2018 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 117 1.8E-33 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 223 1.8E-33 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 Gene3D G3DSA:1.10.8.50 135 276 3.6E-51 T 29-03-2018 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 44.983 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 SUPERFAMILY SSF46946 134 223 1.57E-30 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 1.3E-117 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 SMART SM01232 134 226 1.6E-49 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 SMART SM00898 2 118 3.5E-52 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 SUPERFAMILY SSF81624 2 138 7.85E-43 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 Gene3D G3DSA:3.20.190.10 2 133 7.9E-44 T 29-03-2018 CXR48_RS13440 5b1b4f791840a6ddb09d3e172e46174b 276 Pfam PF06827 Zinc finger found in FPG and IleRS 247 274 5.8E-12 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CXR48_RS14260 68ef584d10061df9b855be7ce9392630 471 Pfam PF00425 chorismate binding enzyme 206 458 6.8E-76 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CXR48_RS14260 68ef584d10061df9b855be7ce9392630 471 SUPERFAMILY SSF56322 49 467 2.09E-100 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CXR48_RS14260 68ef584d10061df9b855be7ce9392630 471 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 117 466 1.3E-109 T 29-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CXR48_RS14260 68ef584d10061df9b855be7ce9392630 471 Hamap MF_01935 Isochorismate synthase MenF [menF]. 1 468 30.451 T 29-03-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CXR48_RS14260 68ef584d10061df9b855be7ce9392630 471 Gene3D G3DSA:3.60.120.10 2 469 1.9E-101 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF56801 1459 2023 5.23E-151 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:3.30.300.30 863 975 9.5E-37 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:3.30.300.30 1900 2013 1.7E-36 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 485 892 2.9E-131 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1522 1929 3.4E-123 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Pfam PF00550 Phosphopantetheine attachment site 973 1034 2.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Pfam PF00550 Phosphopantetheine attachment site 2013 2074 3.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF52777 2278 2532 7.67E-35 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:3.30.559.10 1038 1236 4.5E-41 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2403 2544 4.4E-33 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SMART SM00823 Phosphopantetheine attachment site 971 1040 0.002 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SMART SM00823 Phosphopantetheine attachment site 2010 2078 1.0E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:3.30.559.10 2 190 4.8E-20 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF52777 2083 2289 7.11E-42 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Pfam PF00501 AMP-binding enzyme 464 868 2.1E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Pfam PF00501 AMP-binding enzyme 1501 1905 2.0E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF52777 187 427 3.89E-36 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF52777 8 181 2.0E-33 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Pfam PF13193 AMP-binding enzyme C-terminal domain 876 945 3.4E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Pfam PF13193 AMP-binding enzyme C-terminal domain 1913 1985 6.6E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:2.30.38.10 1808 1897 7.0E-23 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Pfam PF00668 Condensation domain 2087 2537 1.8E-105 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Pfam PF00668 Condensation domain 3 442 4.8E-109 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Pfam PF00668 Condensation domain 1052 1480 1.6E-141 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF52777 1051 1234 7.67E-42 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF47336 2003 2074 4.45E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:3.40.50.980 455 608 3.1E-46 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:3.40.50.980 1492 1649 4.5E-47 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF47336 963 1036 3.6E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:1.10.1200.10 976 1037 1.5E-21 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF52777 1221 1486 4.11E-66 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1644 1655 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2034 2049 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:1.10.1200.10 2014 2076 4.5E-18 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:3.30.559.10 2077 2286 9.7E-33 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 SUPERFAMILY SSF56801 422 983 6.15E-155 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:3.40.50.980 609 776 4.7E-34 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:3.40.50.980 1650 1807 7.0E-33 T 29-03-2018 CXR48_RS09250 5699672146e6a97ae041796634b54fdd 2552 Gene3D G3DSA:2.30.38.10 778 858 2.1E-24 T 29-03-2018 CXR48_RS05455 cf0affadd9312a7e15fd3d586d48a442 270 SUPERFAMILY SSF56784 4 268 5.32E-71 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS05455 cf0affadd9312a7e15fd3d586d48a442 270 Gene3D G3DSA:3.40.50.1000 1 270 1.3E-43 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS05455 cf0affadd9312a7e15fd3d586d48a442 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 264 8.4E-68 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS05455 cf0affadd9312a7e15fd3d586d48a442 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 7 264 1.2E-60 T 29-03-2018 IPR000150 Cof family GO:0016787 CXR48_RS05455 cf0affadd9312a7e15fd3d586d48a442 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 237 2.6E-28 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 Pfam PF00270 DEAD/DEAH box helicase 26 192 3.2E-47 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 Gene3D G3DSA:3.40.50.300 4 218 5.9E-57 T 29-03-2018 CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 SMART SM00490 254 335 1.2E-33 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 SMART SM00487 21 218 1.2E-60 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 Gene3D G3DSA:3.40.50.300 219 449 2.3E-47 T 29-03-2018 CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 SUPERFAMILY SSF52540 69 353 8.12E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 Pfam PF00271 Helicase conserved C-terminal domain 229 335 1.8E-28 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 4 478 75.033 T 29-03-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 CXR48_RS18490 3de334741f35ddc95326ee1d04dc0d23 479 Pfam PF03880 DbpA RNA binding domain 405 475 8.4E-20 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CXR48_RS01950 9f8ed2aad9ccd681c8045c46581ef306 39 Pfam PF11131 Rap-phr extracellular signalling 3 39 2.4E-15 T 29-03-2018 IPR025899 Phosphatase RapC/F inhibitor, PhrC/F CXR48_RS01950 9f8ed2aad9ccd681c8045c46581ef306 39 ProDom PD048351 COMPETENCE SPORULATION FACTOR PHOSPHATASE INHIBITOR RAPC REGULATOR C PHRC 1 39 8.0E-8 T 29-03-2018 IPR020243 Phosphatase RapC inhibitor, PhrC CXR48_RS03065 d94308b1a331231158a608454792907e 252 Pfam PF00902 Sec-independent protein translocase protein (TatC) 13 221 6.4E-58 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS03065 d94308b1a331231158a608454792907e 252 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 11 226 1.4E-72 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS03065 d94308b1a331231158a608454792907e 252 ProSitePatterns PS01218 TatC family signature. 154 173 - T 29-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site CXR48_RS03065 d94308b1a331231158a608454792907e 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 10 37 1.3E-41 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS03065 d94308b1a331231158a608454792907e 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 102 128 1.3E-41 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS03065 d94308b1a331231158a608454792907e 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 84 102 1.3E-41 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS03065 d94308b1a331231158a608454792907e 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 1.3E-41 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS03065 d94308b1a331231158a608454792907e 252 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 241 17.954 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 SUPERFAMILY SSF57783 4 98 1.7E-36 T 29-03-2018 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 Gene3D G3DSA:1.10.860.10 467 563 1.1E-10 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 SMART SM00493 262 333 6.4E-17 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 Pfam PF13155 Toprim-like 265 350 8.6E-19 T 29-03-2018 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 Gene3D G3DSA:3.90.580.10 1 102 6.6E-37 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 Hamap MF_00974 DNA primase [dnaG]. 4 593 30.089 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 SUPERFAMILY SSF56731 117 426 3.27E-102 T 29-03-2018 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 Gene3D G3DSA:3.40.1360.10 244 367 1.1E-32 T 29-03-2018 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 Pfam PF10410 DnaB-helicase binding domain of primase 371 425 5.5E-11 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 TIGRFAM TIGR01391 dnaG: DNA primase 4 420 1.5E-150 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 Pfam PF01807 CHC2 zinc finger 6 99 6.9E-40 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 255 1.3E-45 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 Gene3D G3DSA:3.90.980.10 110 243 2.0E-46 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 SMART SM00400 36 90 8.0E-36 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 SUPERFAMILY SSF48024 462 563 1.44E-8 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CXR48_RS12105 8338105b05e6264a6c0a55231a162220 603 PIRSF PIRSF002811 2 603 1.6E-202 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 Hamap MF_00551 Uridine kinase [udk]. 2 206 42.37 T 29-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 Gene3D G3DSA:3.40.50.300 1 211 3.4E-62 T 29-03-2018 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 192 3.6E-44 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 SUPERFAMILY SSF52540 3 197 7.43E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 35 46 5.3E-38 T 29-03-2018 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 150 161 5.3E-38 T 29-03-2018 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 5 22 5.3E-38 T 29-03-2018 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 172 185 5.3E-38 T 29-03-2018 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 136 146 5.3E-38 T 29-03-2018 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 80 95 5.3E-38 T 29-03-2018 CXR48_RS12575 5d90fa37b417ff6174546430f7ba8705 211 TIGRFAM TIGR00235 udk: uridine kinase 4 206 8.6E-97 T 29-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Pfam PF08659 KR domain 1667 1845 1.5E-40 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SUPERFAMILY SSF51735 1483 1653 1.38E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 686 803 1.0E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SMART SM00825 Beta-ketoacyl synthase 427 865 3.6E-181 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 426 678 1.4E-82 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1667 1847 5.8E-24 T 29-03-2018 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SUPERFAMILY SSF51735 1665 1884 1.37E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SUPERFAMILY SSF47336 920 993 2.22E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Gene3D G3DSA:1.10.1200.10 291 389 1.7E-12 T 29-03-2018 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Gene3D G3DSA:3.10.129.10 1159 1285 1.4E-16 T 29-03-2018 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Gene3D G3DSA:3.10.129.10 4 110 1.4E-4 T 29-03-2018 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Pfam PF14765 Polyketide synthase dehydratase 9 270 4.5E-19 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Pfam PF14765 Polyketide synthase dehydratase 1157 1441 8.4E-57 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SMART SM00823 Phosphopantetheine attachment site 924 995 9.5E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SMART SM00823 Phosphopantetheine attachment site 314 385 9.1E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SUPERFAMILY SSF47336 316 439 1.09E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SUPERFAMILY SSF53901 422 794 1.41E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Pfam PF00550 Phosphopantetheine attachment site 926 991 4.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Pfam PF00550 Phosphopantetheine attachment site 316 381 3.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Gene3D G3DSA:3.40.47.10 417 690 1.7E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Gene3D G3DSA:1.10.1200.10 911 999 2.1E-13 T 29-03-2018 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Gene3D G3DSA:3.40.47.10 693 863 1.5E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 807 904 1.6E-10 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SMART SM00826 1157 1323 2.1E-8 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 Gene3D G3DSA:3.40.50.720 1662 1893 1.4E-34 T 29-03-2018 CXR48_RS11350 165b35c39c3c3879640b4475615d4775 1908 SMART SM01294 315 381 8.1E-6 T 29-03-2018 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 SUPERFAMILY SSF103190 92 189 1.41E-12 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 Pfam PF02743 Cache domain 49 214 9.4E-20 T 29-03-2018 IPR033479 Double Cache domain 1 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 SUPERFAMILY SSF47384 280 355 3.73E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 Gene3D G3DSA:3.30.565.10 356 505 1.1E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 SMART SM00387 398 504 5.7E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 Gene3D G3DSA:3.30.450.20 50 125 1.6E-22 T 29-03-2018 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 Gene3D G3DSA:3.30.450.20 163 216 7.5E-7 T 29-03-2018 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 Gene3D G3DSA:1.10.287.130 273 351 2.4E-15 T 29-03-2018 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 Pfam PF00512 His Kinase A (phospho-acceptor) domain 292 353 4.5E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 449 1.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 482 1.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 463 1.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 501 1.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 SUPERFAMILY SSF55874 356 501 2.23E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 401 502 3.8E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06760 e674d2f0b5f845f58aff805c9e782e3e 505 SMART SM00388 290 355 3.0E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 Gene3D G3DSA:1.10.10.10 210 260 4.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 188 196 2.8E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 348 359 2.8E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 164 177 2.8E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 333 348 2.8E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 312 324 2.8E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF04545 Sigma-70, region 4 308 361 5.1E-20 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 SUPERFAMILY SSF88946 101 210 4.32E-53 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 9 373 34.124 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF04539 Sigma-70 region 3 219 295 4.1E-33 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF00140 Sigma-70 factor, region 1.2 102 135 5.2E-16 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 Gene3D G3DSA:1.10.10.10 302 373 6.5E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 333 359 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF03979 Sigma-70 factor, region 1.1 16 85 1.3E-15 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 SUPERFAMILY SSF88659 270 371 5.42E-30 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 138 361 1.0E-39 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 SUPERFAMILY SSF88659 213 286 1.29E-23 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 137 372 1.0E-125 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF04542 Sigma-70 region 2 140 209 3.3E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 164 177 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12100 f91c537863ddbb75ccac15f7c36fb2e4 373 Gene3D G3DSA:1.10.601.10 1 209 2.0E-75 T 29-03-2018 CXR48_RS04045 2ad6522e2ff3a5f1de76d0aa76f04aff 200 Gene3D G3DSA:3.40.50.360 1 198 7.3E-41 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS04045 2ad6522e2ff3a5f1de76d0aa76f04aff 200 SUPERFAMILY SSF52218 1 192 1.71E-48 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS04045 2ad6522e2ff3a5f1de76d0aa76f04aff 200 Pfam PF02525 Flavodoxin-like fold 1 185 1.0E-36 T 29-03-2018 IPR003680 Flavodoxin-like fold CXR48_RS12320 0ccbe762b9d915f74f6706717cfabb27 193 Pfam PF01966 HD domain 18 130 1.4E-16 T 29-03-2018 IPR006674 HD domain CXR48_RS12320 0ccbe762b9d915f74f6706717cfabb27 193 SUPERFAMILY SSF109604 4 185 1.13E-36 T 29-03-2018 CXR48_RS12320 0ccbe762b9d915f74f6706717cfabb27 193 Gene3D G3DSA:1.10.3210.10 1 187 1.1E-29 T 29-03-2018 CXR48_RS12320 0ccbe762b9d915f74f6706717cfabb27 193 SMART SM00471 14 141 2.7E-11 T 29-03-2018 IPR003607 HD/PDEase domain CXR48_RS12320 0ccbe762b9d915f74f6706717cfabb27 193 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 181 3.7E-74 T 29-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CXR48_RS05865 9bd794a7f8cfb53dee59453c1228e374 391 PIRSF PIRSF001434 1 385 2.7E-143 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CXR48_RS05865 9bd794a7f8cfb53dee59453c1228e374 391 Gene3D G3DSA:3.90.1150.10 252 391 3.2E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS05865 9bd794a7f8cfb53dee59453c1228e374 391 Gene3D G3DSA:3.40.640.10 6 250 4.5E-59 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS05865 9bd794a7f8cfb53dee59453c1228e374 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 382 1.1E-147 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CXR48_RS05865 9bd794a7f8cfb53dee59453c1228e374 391 SUPERFAMILY SSF53383 21 384 6.66E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS05865 9bd794a7f8cfb53dee59453c1228e374 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 192 206 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 SUPERFAMILY SSF56420 2 182 1.7E-58 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 180 7.3E-54 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 PIRSF PIRSF004749 2 184 8.0E-48 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 Pfam PF01327 Polypeptide deformylase 4 171 4.9E-46 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 PRINTS PR01576 Peptide deformylase signature 121 139 2.9E-30 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 PRINTS PR01576 Peptide deformylase signature 47 76 2.9E-30 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 PRINTS PR01576 Peptide deformylase signature 108 119 2.9E-30 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 PRINTS PR01576 Peptide deformylase signature 140 169 2.9E-30 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 Hamap MF_00163 Peptide deformylase [def]. 3 182 27.368 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07200 5665bb7c399bada833a31343ffaf8fbf 184 Gene3D G3DSA:3.90.45.10 3 184 3.1E-53 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SUPERFAMILY SSF51735 1702 1938 2.57E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SUPERFAMILY SSF47336 1978 2105 1.96E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2238 2254 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Gene3D G3DSA:1.10.1200.10 1956 2056 3.6E-18 T 29-03-2018 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SUPERFAMILY SSF53901 874 1242 1.04E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Gene3D G3DSA:3.40.50.720 599 863 7.1E-40 T 29-03-2018 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Gene3D G3DSA:3.40.50.720 1698 1955 1.0E-37 T 29-03-2018 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2007 2022 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SMART SM00823 Phosphopantetheine attachment site 330 401 6.5E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SMART SM00823 Phosphopantetheine attachment site 1981 2052 1.8E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1255 1370 2.2E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF14765 Polyketide synthase dehydratase 22 288 7.4E-30 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF00550 Phosphopantetheine attachment site 1982 2047 2.0E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF00550 Phosphopantetheine attachment site 332 397 2.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Gene3D G3DSA:3.40.47.10 2341 2505 7.5E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Gene3D G3DSA:3.40.47.10 1141 1305 1.9E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SUPERFAMILY SSF51735 602 849 2.04E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 607 789 2.7E-44 T 29-03-2018 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1704 1901 1.0E-40 T 29-03-2018 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Gene3D G3DSA:3.40.47.10 2083 2337 3.6E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Gene3D G3DSA:3.40.47.10 869 1138 5.9E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 878 1126 3.9E-75 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2091 2325 5.4E-60 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SUPERFAMILY SSF53901 2088 2446 1.73E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF08659 KR domain 1706 1900 1.5E-39 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF08659 KR domain 607 788 1.7E-52 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SUPERFAMILY SSF47336 325 400 2.75E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1134 1251 2.2E-39 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2333 2449 6.3E-29 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Gene3D G3DSA:1.10.1200.10 311 403 6.1E-11 T 29-03-2018 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SUPERFAMILY SSF51735 1482 1688 9.05E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 Gene3D G3DSA:3.10.129.10 6 104 3.8E-8 T 29-03-2018 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SMART SM01294 331 397 1.7E-4 T 29-03-2018 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SMART SM01294 1982 2048 1.4E-4 T 29-03-2018 CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SMART SM00825 Beta-ketoacyl synthase 879 1307 1.1E-177 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11340 d3990b42f816737d85a61e02bd3be5b2 2572 SMART SM00825 Beta-ketoacyl synthase 2093 2503 1.5E-110 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 2.1E-32 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 2.1E-32 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 2.1E-32 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 2.1E-32 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 1.8E-6 T 29-03-2018 CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 1.8E-6 T 29-03-2018 CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 9 472 2.5E-252 T 29-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 Gene3D G3DSA:1.10.40.30 418 465 2.4E-19 T 29-03-2018 CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 Gene3D G3DSA:1.20.200.10 142 417 1.6E-81 T 29-03-2018 CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 SUPERFAMILY SSF48557 8 465 9.27E-149 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 Gene3D G3DSA:1.10.275.10 6 141 3.3E-54 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 Pfam PF10415 Fumarase C C-terminus 412 464 2.9E-19 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS11190 4b9caa179451106f1f5d7ffc6f4a33ba 475 Pfam PF00206 Lyase 16 345 8.0E-117 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CXR48_RS01150 503f9de0e974b52ffb1afe4ac037ead0 234 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 227 3.7E-85 T 29-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CXR48_RS01150 503f9de0e974b52ffb1afe4ac037ead0 234 Gene3D G3DSA:3.40.50.1000 92 233 3.9E-25 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS01150 503f9de0e974b52ffb1afe4ac037ead0 234 Gene3D G3DSA:1.10.150.240 17 91 9.5E-22 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CXR48_RS01150 503f9de0e974b52ffb1afe4ac037ead0 234 SUPERFAMILY SSF56784 4 227 1.02E-43 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS01150 503f9de0e974b52ffb1afe4ac037ead0 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 199 1.2E-18 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS01150 503f9de0e974b52ffb1afe4ac037ead0 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 194 2.1E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 SMART SM00382 362 547 2.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 Pfam PF00005 ABC transporter 353 500 3.9E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 5 531 2.2E-176 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 Gene3D G3DSA:1.20.1560.10 5 314 1.4E-24 T 29-03-2018 CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 SUPERFAMILY SSF52540 331 570 1.46E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 Gene3D G3DSA:3.40.50.300 320 572 6.4E-66 T 29-03-2018 CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 Pfam PF00664 ABC transporter transmembrane region 18 277 1.1E-9 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 SUPERFAMILY SSF90123 3 301 7.85E-41 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS18375 0c5a052e15c2a3dd0aa6890920a164a4 576 SUPERFAMILY SSF90123 477 490 7.85E-41 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS08050 a854411afeb8fff1ea482d56cef7d999 181 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 41.244 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CXR48_RS08050 a854411afeb8fff1ea482d56cef7d999 181 PIRSF PIRSF039093 1 181 8.9E-85 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CXR48_RS08050 a854411afeb8fff1ea482d56cef7d999 181 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 6.7E-83 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CXR48_RS08050 a854411afeb8fff1ea482d56cef7d999 181 Gene3D G3DSA:3.60.20.10 7 181 1.1E-25 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS08050 a854411afeb8fff1ea482d56cef7d999 181 SUPERFAMILY SSF56235 4 180 3.87E-59 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS08050 a854411afeb8fff1ea482d56cef7d999 181 Pfam PF00227 Proteasome subunit 5 177 3.0E-26 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS05825 53d137090fd8c9ac4b44d0b8a6702864 249 ProSitePatterns PS00744 Beta-lactamases class B signature 2. 179 191 - T 29-03-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 CXR48_RS05825 53d137090fd8c9ac4b44d0b8a6702864 249 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 103 122 - T 29-03-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 CXR48_RS05825 53d137090fd8c9ac4b44d0b8a6702864 249 SUPERFAMILY SSF56281 21 249 5.77E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS05825 53d137090fd8c9ac4b44d0b8a6702864 249 Gene3D G3DSA:3.60.15.10 20 247 1.5E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS05825 53d137090fd8c9ac4b44d0b8a6702864 249 Pfam PF00753 Metallo-beta-lactamase superfamily 57 230 8.9E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS05825 53d137090fd8c9ac4b44d0b8a6702864 249 SMART SM00849 59 230 4.4E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS06755 f661d28dfd3ba8aa6737f6231dd22b2c 86 Pfam PF09388 Spo0E like sporulation regulatory protein 10 51 2.9E-12 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CXR48_RS06755 f661d28dfd3ba8aa6737f6231dd22b2c 86 SUPERFAMILY SSF140500 6 57 7.85E-15 T 29-03-2018 CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 SMART SM00382 37 149 5.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 125 9.9E-16 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 Pfam PF16193 AAA C-terminal domain 172 251 2.0E-27 T 29-03-2018 IPR032423 AAA C-terminal domain CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 Gene3D G3DSA:1.10.8.60 138 227 7.5E-22 T 29-03-2018 CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 Pfam PF12002 MgsA AAA+ ATPase C terminal 252 417 1.1E-67 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 SUPERFAMILY SSF52540 2 228 1.44E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 Gene3D G3DSA:1.10.3710.10 332 422 1.4E-32 T 29-03-2018 CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 Gene3D G3DSA:1.20.272.10 236 329 4.1E-37 T 29-03-2018 CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 Pfam PF03215 Rad17 cell cycle checkpoint protein 141 204 4.3E-5 T 29-03-2018 CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 Gene3D G3DSA:3.40.50.300 1 137 4.1E-26 T 29-03-2018 CXR48_RS12685 e7ae18703cb026963f9fa1913c9d8a2d 422 SUPERFAMILY SSF48019 237 420 3.0E-73 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CXR48_RS01505 d7a68e8389755a1753441d3e74d8ba6f 167 SUPERFAMILY SSF55166 43 165 1.12E-30 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CXR48_RS01505 d7a68e8389755a1753441d3e74d8ba6f 167 Gene3D G3DSA:3.30.1380.10 28 164 1.1E-31 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CXR48_RS01505 d7a68e8389755a1753441d3e74d8ba6f 167 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 95 164 1.2E-18 T 29-03-2018 CXR48_RS10025 7138f10c7f7d864b08937efb7e2eae79 212 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 6 206 3.5E-70 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CXR48_RS10025 7138f10c7f7d864b08937efb7e2eae79 212 Pfam PF03006 Haemolysin-III related 2 197 6.3E-39 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CXR48_RS03910 8706c841b7da38b7f09968a6de357fd5 373 Pfam PF13353 4Fe-4S single cluster domain 41 114 3.7E-5 T 29-03-2018 CXR48_RS03910 8706c841b7da38b7f09968a6de357fd5 373 Pfam PF08756 YfkB-like domain 221 371 8.0E-78 T 29-03-2018 IPR014866 YfkB-like domain CXR48_RS03910 8706c841b7da38b7f09968a6de357fd5 373 Gene3D G3DSA:3.20.20.70 21 347 3.0E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS03910 8706c841b7da38b7f09968a6de357fd5 373 SUPERFAMILY SSF102114 33 330 1.31E-28 T 29-03-2018 CXR48_RS03910 8706c841b7da38b7f09968a6de357fd5 373 Pfam PF04055 Radical SAM superfamily 37 175 4.0E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS03910 8706c841b7da38b7f09968a6de357fd5 373 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 9 371 9.3E-198 T 29-03-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 25 374 42.647 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 26 87 2.5E-4 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 26 379 1.4E-139 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 Pfam PF02222 ATP-grasp domain 130 299 4.0E-61 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 Gene3D G3DSA:3.40.50.20 24 109 3.9E-24 T 29-03-2018 CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 SUPERFAMILY SSF51246 323 386 6.83E-13 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 SUPERFAMILY SSF56059 121 319 1.08E-62 T 29-03-2018 CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 Gene3D G3DSA:3.30.1490.20 136 199 2.4E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 SUPERFAMILY SSF52440 21 107 2.3E-25 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS03270 5fab5d056fec8d02896857587d8ab77d 393 Gene3D G3DSA:3.30.470.20 200 384 3.0E-37 T 29-03-2018 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 434 35.849 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 Gene3D G3DSA:1.20.120.140 1 92 2.9E-30 T 29-03-2018 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 Gene3D G3DSA:3.40.50.300 100 211 1.3E-17 T 29-03-2018 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 Gene3D G3DSA:1.10.260.30 328 432 5.8E-40 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 8.9E-79 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.4E-22 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 SUPERFAMILY SSF52540 43 355 2.02E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 4.7E-191 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 SUPERFAMILY SSF47446 329 430 3.76E-39 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 Pfam PF02978 Signal peptide binding domain 329 427 1.7E-34 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 SMART SM00963 2 87 3.7E-34 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 SMART SM00382 100 275 3.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 SMART SM00962 101 297 1.3E-119 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07965 a5bf7a644f7c3898f2c761f81afd0842 446 Gene3D G3DSA:1.20.120.140 212 311 1.3E-31 T 29-03-2018 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 SUPERFAMILY SSF103473 8 393 9.68E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 Gene3D G3DSA:1.20.1250.20 193 397 6.3E-26 T 29-03-2018 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 Pfam PF07690 Major Facilitator Superfamily 10 266 8.9E-50 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 PRINTS PR01035 Tetracycline resistance protein signature 337 360 3.2E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 PRINTS PR01035 Tetracycline resistance protein signature 159 179 3.2E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 PRINTS PR01035 Tetracycline resistance protein signature 73 97 3.2E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 PRINTS PR01035 Tetracycline resistance protein signature 16 32 3.2E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 PRINTS PR01035 Tetracycline resistance protein signature 131 153 3.2E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 PRINTS PR01035 Tetracycline resistance protein signature 249 269 3.2E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 PRINTS PR01035 Tetracycline resistance protein signature 277 298 3.2E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS15165 e6c89c8969d438367f634b822880a8e3 398 Gene3D G3DSA:1.20.1250.20 5 192 7.2E-45 T 29-03-2018 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 Gene3D G3DSA:3.40.190.10 1 104 1.2E-45 T 29-03-2018 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 3.7E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 3.7E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 3.7E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 3.7E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 3.7E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 SUPERFAMILY SSF53850 2 216 9.06E-83 T 29-03-2018 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 SUPERFAMILY SSF54782 220 309 1.7E-22 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 PIRSF PIRSF001438 1 310 2.0E-123 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 Gene3D G3DSA:3.30.160.40 220 304 2.7E-21 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 Gene3D G3DSA:3.40.190.10 105 198 5.6E-36 T 29-03-2018 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 2.2E-20 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 39.304 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 295 4.3E-111 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12975 4d198b8135a5f8c07d62a94e75341eba 313 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 4.0E-81 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 Gene3D G3DSA:3.40.50.720 161 313 1.4E-27 T 29-03-2018 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 SUPERFAMILY SSF69742 1 158 1.15E-45 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 SUPERFAMILY SSF69075 318 420 4.71E-14 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 30.117 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 Gene3D G3DSA:1.10.1200.70 332 420 2.3E-19 T 29-03-2018 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 PIRSF PIRSF000445 1 434 3.8E-157 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 2.3E-46 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 3.6E-170 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.2E-45 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 SUPERFAMILY SSF51735 162 314 2.29E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS12985 7533848e628b7f5bed828ee2608f5abf 455 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 320 418 3.2E-19 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 PRINTS PR00126 ATP synthase gamma subunit signature 264 285 9.6E-42 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 PRINTS PR00126 ATP synthase gamma subunit signature 233 252 9.6E-42 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 9.6E-42 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 9.6E-42 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 272 285 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 Gene3D G3DSA:1.10.287.80 239 281 1.7E-15 T 29-03-2018 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 Gene3D G3DSA:1.10.287.80 2 41 3.2E-18 T 29-03-2018 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 Pfam PF00231 ATP synthase 3 286 1.4E-100 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 Gene3D G3DSA:3.40.1380.10 42 238 8.9E-74 T 29-03-2018 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 286 36.087 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 286 9.7E-115 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17405 5a61b77c294015ddf60eaf8b4e804b6c 287 SUPERFAMILY SSF52943 2 286 1.31E-92 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS00080 7c81c14b0358d8a91dca4b4323e9b340 294 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 294 1.7E-160 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00080 7c81c14b0358d8a91dca4b4323e9b340 294 SUPERFAMILY SSF51366 18 269 7.53E-70 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CXR48_RS00080 7c81c14b0358d8a91dca4b4323e9b340 294 ProSitePatterns PS01235 PdxS/SNZ family signature. 205 223 - T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00080 7c81c14b0358d8a91dca4b4323e9b340 294 Pfam PF01680 SOR/SNZ family 8 212 1.1E-106 T 29-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00080 7c81c14b0358d8a91dca4b4323e9b340 294 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 4 294 53.864 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00080 7c81c14b0358d8a91dca4b4323e9b340 294 PIRSF PIRSF029271 1 294 9.5E-154 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00080 7c81c14b0358d8a91dca4b4323e9b340 294 Gene3D G3DSA:3.20.20.70 18 271 2.1E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:3.40.50.980 242 394 1.0E-44 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF13193 AMP-binding enzyme C-terminal domain 1686 1759 7.9E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF13193 AMP-binding enzyme C-terminal domain 653 726 9.1E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF52777 1868 2043 6.67E-35 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF47336 745 818 6.81E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF52777 27 213 2.22E-8 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:3.30.559.10 2327 2536 1.6E-33 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:3.30.559.10 821 1023 2.1E-31 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:3.30.559.10 1854 2070 3.3E-31 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2173 2323 1.4E-42 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:2.30.38.10 1588 1668 6.8E-24 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:2.30.38.10 553 635 3.8E-23 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF00668 Condensation domain 2331 2538 1.7E-50 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF00668 Condensation domain 835 1268 3.2E-115 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF00668 Condensation domain 27 230 2.1E-5 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF00668 Condensation domain 1865 2301 2.3E-97 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF52777 2050 2299 7.34E-33 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:1.10.1200.10 1790 1853 4.6E-15 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF47336 1779 1850 8.38E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:3.40.50.980 1433 1586 1.2E-26 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF52777 1009 1274 4.0E-56 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF52777 2336 2513 1.19E-40 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF56801 1246 1799 6.8E-153 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF00550 Phosphopantetheine attachment site 755 818 2.9E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF00550 Phosphopantetheine attachment site 1789 1850 1.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 391 402 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF56801 241 765 1.31E-145 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SMART SM00823 Phosphopantetheine attachment site 753 822 0.0021 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1810 1825 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:1.10.1200.10 759 820 1.1E-21 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:3.40.50.980 1279 1432 6.1E-47 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:3.40.50.980 395 544 4.6E-34 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 SUPERFAMILY SSF52777 841 1002 1.78E-35 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1309 1702 2.1E-127 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 271 669 2.0E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:3.30.300.30 640 758 1.2E-35 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Gene3D G3DSA:3.30.300.30 1673 1789 2.0E-33 T 29-03-2018 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF00501 AMP-binding enzyme 249 645 2.9E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 Pfam PF00501 AMP-binding enzyme 1288 1678 5.8E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01190 689dc0875df6d6dfc48aeb62297e0f01 2540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1427 1438 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF46955 413 483 1.83E-19 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 797 46.186 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:2.40.50.140 55 161 3.4E-42 T 29-03-2018 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF55681 475 697 1.99E-50 T 29-03-2018 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SMART SM00873 221 394 8.1E-90 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Pfam PF03147 Ferredoxin-fold anticodon binding domain 710 803 2.0E-29 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SMART SM00896 710 803 1.2E-45 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.30.56.10 410 483 2.4E-24 T 29-03-2018 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF54991 705 803 3.92E-32 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.30.70.380 706 803 3.5E-28 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SMART SM00874 411 479 1.4E-27 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF56037 209 405 2.59E-70 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF50249 36 199 7.35E-46 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 803 2.2E-269 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Pfam PF03483 B3/4 domain 222 394 1.8E-64 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.50.40.10 204 405 1.1E-70 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Pfam PF01588 Putative tRNA binding domain 46 152 4.0E-27 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Pfam PF03484 tRNA synthetase B5 domain 414 479 2.4E-20 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.30.56.10 1 54 6.6E-12 T 29-03-2018 CXR48_RS13225 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.30.930.10 498 697 4.8E-36 T 29-03-2018 CXR48_RS15935 4775766bb6d950452ca8e74a9a49d114 185 Gene3D G3DSA:1.10.10.10 1 181 1.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15935 4775766bb6d950452ca8e74a9a49d114 185 PIRSF PIRSF006707 2 185 1.0E-47 T 29-03-2018 IPR026282 DNA-binding protein, MJ1563 type CXR48_RS15935 4775766bb6d950452ca8e74a9a49d114 185 SUPERFAMILY SSF46785 11 160 1.39E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15935 4775766bb6d950452ca8e74a9a49d114 185 Pfam PF12802 MarR family 28 79 2.4E-6 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.30.559.10 2081 2284 1.6E-41 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.30.559.10 3 211 4.8E-37 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF47336 963 1070 5.5E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.40.50.980 1648 1810 7.7E-37 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.40.50.980 2699 2846 6.8E-27 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF56801 431 984 1.27E-153 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF52777 190 434 8.56E-49 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1642 1653 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF52777 3116 3295 4.37E-39 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.30.559.10 1042 1233 1.0E-41 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF52777 2269 2511 2.11E-57 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 ProSitePatterns PS00012 Phosphopantetheine attachment site. 994 1009 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:2.30.38.10 2847 2926 1.1E-21 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:2.30.38.10 774 854 1.4E-22 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2035 2050 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:1.10.1200.10 2018 2080 1.5E-20 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF56801 1462 2023 3.79E-149 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF52777 1226 1467 3.89E-62 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3066 3081 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 ProSitePatterns PS00455 Putative AMP-binding domain signature. 611 622 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2693 2704 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:1.10.1200.10 975 1041 2.2E-19 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.40.50.980 462 614 5.2E-47 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.40.50.980 2539 2698 2.1E-47 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.40.50.980 1495 1647 2.2E-46 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00550 Phosphopantetheine attachment site 2012 2076 9.8E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00550 Phosphopantetheine attachment site 972 1035 6.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00550 Phosphopantetheine attachment site 3045 3106 1.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.40.50.980 615 764 6.1E-36 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00501 AMP-binding enzyme 2548 2936 1.4E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00501 AMP-binding enzyme 1503 1904 7.7E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00501 AMP-binding enzyme 471 864 2.2E-101 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF56801 2507 3055 3.53E-152 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:1.10.1200.10 3048 3109 2.0E-21 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.30.559.10 3110 3324 1.6E-30 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00668 Condensation domain 1054 1484 7.1E-140 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00668 Condensation domain 2094 2528 5.1E-140 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00668 Condensation domain 3120 3569 8.9E-123 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF00668 Condensation domain 7 450 5.3E-137 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF52777 3306 3557 2.45E-38 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 492 887 8.1E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1523 1928 2.1E-133 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2569 2960 9.7E-122 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF52777 2099 2263 3.34E-45 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF52777 12 189 4.89E-43 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:2.30.38.10 1817 1896 3.7E-21 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.30.300.30 859 974 5.5E-38 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.30.300.30 1899 2017 4.8E-35 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Gene3D G3DSA:3.30.300.30 2931 3047 2.0E-39 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3428 3576 4.6E-51 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF13193 AMP-binding enzyme C-terminal domain 2944 3016 2.5E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF13193 AMP-binding enzyme C-terminal domain 1912 1984 2.5E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 Pfam PF13193 AMP-binding enzyme C-terminal domain 872 945 9.7E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF47336 3035 3107 2.09E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF52777 1060 1222 6.08E-45 T 29-03-2018 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SMART SM00823 Phosphopantetheine attachment site 3042 3110 7.1E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SMART SM00823 Phosphopantetheine attachment site 971 1039 0.0014 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SMART SM00823 Phosphopantetheine attachment site 2011 2080 0.0046 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01790 0d2240c829147d9d4bddccbdcd861e10 3586 SUPERFAMILY SSF47336 2005 2110 4.84E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS03110 af5e024b034e405a8c63351363aaf2db 479 Gene3D G3DSA:3.40.50.150 1 272 3.8E-49 T 29-03-2018 CXR48_RS03110 af5e024b034e405a8c63351363aaf2db 479 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 41 46 - T 29-03-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 CXR48_RS03110 af5e024b034e405a8c63351363aaf2db 479 Pfam PF01555 DNA methylase 37 271 2.4E-46 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CXR48_RS03110 af5e024b034e405a8c63351363aaf2db 479 SUPERFAMILY SSF53335 5 270 6.69E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS03110 af5e024b034e405a8c63351363aaf2db 479 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 232 250 3.7E-19 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CXR48_RS03110 af5e024b034e405a8c63351363aaf2db 479 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 74 94 3.7E-19 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CXR48_RS03110 af5e024b034e405a8c63351363aaf2db 479 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 255 275 3.7E-19 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CXR48_RS03110 af5e024b034e405a8c63351363aaf2db 479 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 36 50 3.7E-19 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CXR48_RS03110 af5e024b034e405a8c63351363aaf2db 479 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 213 230 3.7E-19 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1791 1806 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.50.720 3450 3590 0.066 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF53901 2309 2328 1.84E-94 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF53901 1888 2264 1.84E-94 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.47.10 1884 2157 6.0E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.47.10 406 678 5.0E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4169 4185 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF53901 410 782 8.3E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3088 3205 3.3E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4264 4378 1.6E-32 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 675 792 2.5E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2154 2270 9.9E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:1.10.1200.10 1757 1881 2.5E-14 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:1.10.1200.10 2566 2693 3.6E-20 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF51735 3437 3617 8.53E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF47336 4024 4038 2.75E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF47336 3918 3991 2.75E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF47336 2701 2781 1.96E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF08659 KR domain 3641 3832 1.2E-40 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF08659 KR domain 1491 1676 1.5E-50 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF51735 1489 1715 2.3E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4024 4256 2.7E-61 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 414 667 1.9E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1892 2146 3.3E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2835 3080 5.1E-84 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2600 2615 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF00550 Phosphopantetheine attachment site 1768 1830 1.3E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF00550 Phosphopantetheine attachment site 314 379 7.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF00550 Phosphopantetheine attachment site 2711 2776 1.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF00550 Phosphopantetheine attachment site 2576 2641 3.0E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF00550 Phosphopantetheine attachment site 3921 3986 1.5E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF47336 1876 1904 7.46E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF47336 1762 1836 7.46E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.10.129.10 1026 1158 2.5E-17 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.10.129.10 4 116 5.8E-7 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.47.10 2161 2331 3.3E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.47.10 3095 3256 9.7E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.47.10 4271 4428 7.3E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.47.10 682 852 8.8E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF53901 4023 4373 1.08E-67 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2275 2373 3.7E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 796 893 2.1E-8 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3208 3318 6.5E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.47.10 4016 4268 1.3E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.47.10 2827 3092 1.5E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3638 3833 2.0E-39 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1491 1677 7.4E-40 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:1.10.1200.10 3896 3991 1.0E-14 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF53901 2835 3198 1.2E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00826 1029 1192 8.1E-16 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00823 Phosphopantetheine attachment site 3919 3990 4.4E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00823 Phosphopantetheine attachment site 2573 2645 4.3E-21 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00823 Phosphopantetheine attachment site 312 383 0.002 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00823 Phosphopantetheine attachment site 2708 2780 7.6E-17 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00823 Phosphopantetheine attachment site 1765 1835 1.2E-11 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF47336 307 428 5.63E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3945 3960 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF14765 Polyketide synthase dehydratase 12 277 1.8E-20 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Pfam PF14765 Polyketide synthase dehydratase 1029 1311 2.3E-55 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:1.10.1200.10 296 387 1.5E-10 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:1.10.1200.10 2694 2790 1.8E-18 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00825 Beta-ketoacyl synthase 416 854 2.0E-198 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00825 Beta-ketoacyl synthase 2837 3258 2.3E-191 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00825 Beta-ketoacyl synthase 4026 4430 6.4E-102 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM00825 Beta-ketoacyl synthase 1894 2333 1.4E-208 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF51735 3633 3876 2.02E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF51735 1374 1473 2.32E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM01294 2575 2641 1.9E-41 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM01294 3920 3986 1.0E-8 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SMART SM01294 2710 2776 4.8E-39 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 SUPERFAMILY SSF47336 2569 2655 8.24E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.50.720 1483 1748 4.4E-38 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 Gene3D G3DSA:3.40.50.720 3631 3895 5.5E-35 T 29-03-2018 CXR48_RS08565 c1a6674f3189130ac8774d418b57a3ab 4474 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2735 2750 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08425 4ab0dde34440214ae5cc33afbf29c4a1 85 PIRSF PIRSF004764 1 85 5.7E-28 T 29-03-2018 IPR024702 Uncharacterised conserved protein YmfJ CXR48_RS08425 4ab0dde34440214ae5cc33afbf29c4a1 85 Pfam PF11588 Protein of unknown function (DUF3243) 2 80 8.7E-35 T 29-03-2018 IPR021637 Protein of unknown function DUF3243 CXR48_RS07740 f454317b28cd6c1e065007d68cf76297 311 SUPERFAMILY SSF51395 2 300 1.73E-87 T 29-03-2018 CXR48_RS07740 f454317b28cd6c1e065007d68cf76297 311 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 2 299 41.355 T 29-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CXR48_RS07740 f454317b28cd6c1e065007d68cf76297 311 Pfam PF01180 Dihydroorotate dehydrogenase 1 284 1.2E-95 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CXR48_RS07740 f454317b28cd6c1e065007d68cf76297 311 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 38 57 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CXR48_RS07740 f454317b28cd6c1e065007d68cf76297 311 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 2 300 5.2E-134 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CXR48_RS07740 f454317b28cd6c1e065007d68cf76297 311 PIRSF PIRSF000164 1 301 2.2E-88 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CXR48_RS07740 f454317b28cd6c1e065007d68cf76297 311 Gene3D G3DSA:3.20.20.70 1 310 1.1E-62 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS12630 38614a216d596165beee01764f567448 275 Gene3D G3DSA:3.40.190.10 38 195 2.5E-39 T 29-03-2018 CXR48_RS12630 38614a216d596165beee01764f567448 275 Gene3D G3DSA:3.40.190.10 196 275 7.6E-19 T 29-03-2018 CXR48_RS12630 38614a216d596165beee01764f567448 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 50 270 2.9E-59 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS12630 38614a216d596165beee01764f567448 275 SMART SM00079 49 271 4.0E-5 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CXR48_RS12630 38614a216d596165beee01764f567448 275 SMART SM00062 49 272 1.9E-83 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS12630 38614a216d596165beee01764f567448 275 SUPERFAMILY SSF53850 6 271 1.24E-68 T 29-03-2018 CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 Gene3D G3DSA:3.10.350.10 46 106 1.0E-14 T 29-03-2018 CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 SMART SM00636 100 407 1.6E-34 T 29-03-2018 IPR011583 Chitinase II GO:0008061 CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 SMART SM00257 1 43 3.2E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 SMART SM00257 48 92 1.4E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 SUPERFAMILY SSF51445 379 423 1.22E-45 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 SUPERFAMILY SSF51445 125 320 1.22E-45 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 Gene3D G3DSA:3.10.50.10 337 378 4.8E-21 T 29-03-2018 IPR029070 Chitinase insertion domain CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 SUPERFAMILY SSF54106 47 92 3.4E-10 T 29-03-2018 IPR018392 LysM domain CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 Gene3D G3DSA:3.20.20.80 114 336 2.6E-25 T 29-03-2018 CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 Pfam PF01476 LysM domain 49 92 1.4E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 Pfam PF01476 LysM domain 2 43 6.4E-14 T 29-03-2018 IPR018392 LysM domain CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 Gene3D G3DSA:3.10.350.10 1 45 8.9E-14 T 29-03-2018 CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 SUPERFAMILY SSF54106 1 43 1.06E-9 T 29-03-2018 IPR018392 LysM domain CXR48_RS00115 0a4d7db64eaeb485376d9c59acc4f4b3 427 Pfam PF00704 Glycosyl hydrolases family 18 148 405 8.5E-27 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CXR48_RS11975 a1543d830b2a6817547ced8c8910765a 154 Pfam PF02618 YceG-like family 93 153 1.1E-6 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 SUPERFAMILY SSF46785 4 76 2.86E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 Gene3D G3DSA:3.40.50.1360 73 235 3.6E-36 T 29-03-2018 CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 SUPERFAMILY SSF100950 74 231 4.6E-26 T 29-03-2018 CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 Gene3D G3DSA:1.10.10.10 2 65 2.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 SMART SM01134 73 232 3.8E-65 T 29-03-2018 CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 8.0E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 Pfam PF00455 DeoR C terminal sensor domain 76 231 1.2E-49 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 SMART SM00420 6 58 4.2E-12 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.9E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS17170 884acdf30518fc4053f318a01f65cd92 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.9E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 SMART SM00798 135 447 3.4E-204 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 Gene3D G3DSA:3.40.50.1380 1 193 4.5E-74 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 PIRSF PIRSF000414 1 512 1.7E-215 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 SUPERFAMILY SSF52335 3 194 3.01E-71 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 Gene3D G3DSA:3.40.140.20 361 502 3.2E-50 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 SUPERFAMILY SSF53927 208 512 2.31E-127 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 Pfam PF02142 MGS-like domain 16 129 2.3E-28 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 512 1.9E-254 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 SMART SM00851 15 130 1.9E-54 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 446 3.0E-121 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 Gene3D G3DSA:3.40.140.20 213 360 8.2E-55 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03315 edfd7cdde1462f74f8add09d798c54fd 512 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 512 45.242 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 SUPERFAMILY SSF47323 644 917 2.43E-72 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 SUPERFAMILY SSF52374 393 640 2.82E-154 T 29-03-2018 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 SUPERFAMILY SSF52374 1 201 2.82E-154 T 29-03-2018 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 Gene3D G3DSA:3.40.50.620 16 621 1.5E-139 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 Pfam PF08264 Anticodon-binding domain of tRNA 677 830 1.0E-30 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 20.598 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 Gene3D G3DSA:3.30.2320.20 792 883 1.4E-23 T 29-03-2018 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 Gene3D G3DSA:1.10.730.10 622 788 3.1E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 562 1.9E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 1.9E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 1.9E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 1.9E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 1.9E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 630 5.7E-221 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 832 0.0 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CXR48_RS07685 02f1f51e4e7448b0880c57bb7e33416d 921 SUPERFAMILY SSF50677 203 393 1.47E-63 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CXR48_RS10605 edcf010fd8db5ebab33a287f3a85652a 56 PIRSF PIRSF036698 1 56 1.2E-37 T 29-03-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA CXR48_RS10605 edcf010fd8db5ebab33a287f3a85652a 56 Pfam PF14084 Protein of unknown function (DUF4264) 4 56 9.9E-25 T 29-03-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA CXR48_RS13550 f19f21f258e01fc873e68d7a25281629 100 Pfam PF14007 YtpI-like protein 5 89 8.8E-32 T 29-03-2018 IPR025618 YtpI-like protein CXR48_RS13940 60c21503986545e10e68b26100dae1e8 545 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 375 523 8.4E-30 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CXR48_RS13940 60c21503986545e10e68b26100dae1e8 545 PIRSF PIRSF038958 1 541 7.9E-157 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CXR48_RS13940 60c21503986545e10e68b26100dae1e8 545 Pfam PF01943 Polysaccharide biosynthesis protein 5 319 6.1E-75 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CXR48_RS15330 51b03e0bba53f252926c1befa8379699 127 Pfam PF01597 Glycine cleavage H-protein 8 126 4.2E-51 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CXR48_RS15330 51b03e0bba53f252926c1befa8379699 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 39.78 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CXR48_RS15330 51b03e0bba53f252926c1befa8379699 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 9.6E-60 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CXR48_RS15330 51b03e0bba53f252926c1befa8379699 127 Gene3D G3DSA:2.40.50.100 5 127 4.8E-49 T 29-03-2018 CXR48_RS15330 51b03e0bba53f252926c1befa8379699 127 SUPERFAMILY SSF51230 3 125 2.09E-45 T 29-03-2018 IPR011053 Single hybrid motif CXR48_RS15330 51b03e0bba53f252926c1befa8379699 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CXR48_RS03665 894d62f5667d7f8a7b4199c7f0ba3e63 116 Pfam PF11486 Protein of unknown function (DUF3212) 5 115 3.8E-48 T 29-03-2018 IPR021579 Protein of unknown function DUF3212 CXR48_RS03665 894d62f5667d7f8a7b4199c7f0ba3e63 116 SUPERFAMILY SSF140688 4 116 4.84E-58 T 29-03-2018 CXR48_RS01115 8cb776acd1735761ff4ef41b090927da 290 SUPERFAMILY SSF52540 3 223 1.01E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01115 8cb776acd1735761ff4ef41b090927da 290 Pfam PF00005 ABC transporter 20 158 2.5E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS01115 8cb776acd1735761ff4ef41b090927da 290 SMART SM00382 29 208 4.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS01115 8cb776acd1735761ff4ef41b090927da 290 Gene3D G3DSA:3.40.50.300 1 263 5.3E-49 T 29-03-2018 CXR48_RS03725 9cccad5a0d4dc1483fa18a89d25e8598 320 SUPERFAMILY SSF53850 64 288 5.83E-15 T 29-03-2018 CXR48_RS03725 9cccad5a0d4dc1483fa18a89d25e8598 320 PIRSF PIRSF017082 1 320 3.0E-94 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CXR48_RS03725 9cccad5a0d4dc1483fa18a89d25e8598 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 316 1.0E-22 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CXR48_RS03725 9cccad5a0d4dc1483fa18a89d25e8598 320 Gene3D G3DSA:3.40.190.10 128 298 1.4E-13 T 29-03-2018 CXR48_RS09560 6d1b8201d19d9b0e08582ca5afb32b63 445 Pfam PF00209 Sodium:neurotransmitter symporter family 5 123 8.4E-27 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS09560 6d1b8201d19d9b0e08582ca5afb32b63 445 Pfam PF00209 Sodium:neurotransmitter symporter family 148 440 4.5E-26 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS09560 6d1b8201d19d9b0e08582ca5afb32b63 445 SUPERFAMILY SSF161070 5 442 7.19E-130 T 29-03-2018 CXR48_RS09560 6d1b8201d19d9b0e08582ca5afb32b63 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 3.9E-15 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS09560 6d1b8201d19d9b0e08582ca5afb32b63 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 3.9E-15 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS09560 6d1b8201d19d9b0e08582ca5afb32b63 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 3.9E-15 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS09560 6d1b8201d19d9b0e08582ca5afb32b63 445 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 Pfam PF12848 ABC transporter 228 318 3.2E-14 T 29-03-2018 IPR032781 ABC-transporter extension domain CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 SUPERFAMILY SSF52540 331 535 9.61E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 Gene3D G3DSA:3.40.50.300 294 541 8.1E-45 T 29-03-2018 CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 SMART SM00382 357 521 7.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 SMART SM00382 26 234 1.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 Pfam PF00005 ABC transporter 18 189 9.5E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 Pfam PF00005 ABC transporter 348 477 8.1E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 SUPERFAMILY SSF52540 130 238 5.77E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 SUPERFAMILY SSF52540 2 92 5.77E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS18975 1902b2536771e6ca17c48e3daaf62465 541 Gene3D G3DSA:3.40.50.300 2 289 6.9E-51 T 29-03-2018 CXR48_RS14035 fba5e1dce15d2102c2d17ecc46b5a05e 231 Gene3D G3DSA:3.40.50.2300 1 123 1.2E-28 T 29-03-2018 CXR48_RS14035 fba5e1dce15d2102c2d17ecc46b5a05e 231 SUPERFAMILY SSF46894 133 222 1.22E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS14035 fba5e1dce15d2102c2d17ecc46b5a05e 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 222 8.2E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS14035 fba5e1dce15d2102c2d17ecc46b5a05e 231 SMART SM00862 148 223 2.2E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS14035 fba5e1dce15d2102c2d17ecc46b5a05e 231 SUPERFAMILY SSF52172 1 126 4.55E-33 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS14035 fba5e1dce15d2102c2d17ecc46b5a05e 231 SMART SM00448 2 112 6.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS14035 fba5e1dce15d2102c2d17ecc46b5a05e 231 Pfam PF00072 Response regulator receiver domain 4 113 4.6E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS14035 fba5e1dce15d2102c2d17ecc46b5a05e 231 Gene3D G3DSA:1.10.10.10 124 228 2.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03130 4e76fa64bf070cfe7502126406e82841 320 Pfam PF00294 pfkB family carbohydrate kinase 4 312 8.0E-80 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CXR48_RS03130 4e76fa64bf070cfe7502126406e82841 320 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CXR48_RS03130 4e76fa64bf070cfe7502126406e82841 320 Gene3D G3DSA:3.40.1190.20 5 320 1.1E-68 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS03130 4e76fa64bf070cfe7502126406e82841 320 SUPERFAMILY SSF53613 5 317 1.71E-80 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS03130 4e76fa64bf070cfe7502126406e82841 320 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 Pfam PF00698 Acyl transferase domain 6 291 7.9E-45 T 29-03-2018 IPR014043 Acyl transferase CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 SUPERFAMILY SSF52151 4 121 8.11E-79 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 SUPERFAMILY SSF52151 190 310 8.11E-79 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 SUPERFAMILY SSF55048 128 193 5.75E-15 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 Gene3D G3DSA:3.30.70.250 143 187 8.1E-21 T 29-03-2018 CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 Gene3D G3DSA:3.40.366.10 188 314 3.1E-32 T 29-03-2018 CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 2.6E-128 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 2.5E-40 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 Gene3D G3DSA:3.40.366.10 3 142 2.4E-44 T 29-03-2018 CXR48_RS07925 e9f95727a9ef21e94b50540eadaa2ca5 317 PIRSF PIRSF000446 1 311 1.4E-137 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 SUPERFAMILY SSF53098 317 464 2.05E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 Gene3D G3DSA:1.10.3500.10 351 493 1.2E-43 T 29-03-2018 IPR023323 Tex-like domain CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 Gene3D G3DSA:1.10.10.650 5 103 2.3E-32 T 29-03-2018 IPR023319 Tex-like protein, HTH domain CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 Pfam PF12836 Helix-hairpin-helix motif 486 550 8.5E-26 T 29-03-2018 CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 SUPERFAMILY SSF50249 633 717 8.95E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 Pfam PF00575 S1 RNA binding domain 646 717 2.4E-18 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 SUPERFAMILY SSF47781 465 553 1.89E-26 T 29-03-2018 IPR010994 RuvA domain 2-like CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 SMART SM00732 321 419 4.4E-38 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 Pfam PF09371 Tex-like protein N-terminal domain 11 195 1.5E-68 T 29-03-2018 IPR018974 Tex-like protein, N-terminal CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 SMART SM00316 647 718 1.2E-23 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 SUPERFAMILY SSF158832 9 316 5.49E-110 T 29-03-2018 CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 Gene3D G3DSA:1.10.3500.10 104 350 5.2E-83 T 29-03-2018 IPR023323 Tex-like domain CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 Pfam PF16921 Tex protein YqgF-like domain 321 446 1.2E-58 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 Gene3D G3DSA:2.40.50.140 638 719 3.9E-23 T 29-03-2018 CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 Gene3D G3DSA:1.10.150.310 494 628 1.8E-44 T 29-03-2018 CXR48_RS02475 e26027b8a4b8e371499eaaac2eda82b5 719 SUPERFAMILY SSF47781 556 630 7.11E-14 T 29-03-2018 IPR010994 RuvA domain 2-like CXR48_RS00725 24750c1ec782f478bfb527b088660374 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 66 77 5.7E-10 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CXR48_RS00725 24750c1ec782f478bfb527b088660374 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 38 46 5.7E-10 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CXR48_RS00725 24750c1ec782f478bfb527b088660374 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 114 128 5.7E-10 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CXR48_RS00725 24750c1ec782f478bfb527b088660374 321 Pfam PF00561 alpha/beta hydrolase fold 36 134 5.1E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS00725 24750c1ec782f478bfb527b088660374 321 SUPERFAMILY SSF53474 19 316 7.12E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS00725 24750c1ec782f478bfb527b088660374 321 Gene3D G3DSA:3.40.50.1820 26 316 2.9E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 Pfam PF04545 Sigma-70, region 4 208 254 2.8E-13 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 258 1.2E-156 T 29-03-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 257 2.2E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 258 8.2E-85 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 Gene3D G3DSA:1.10.10.10 112 164 7.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 PIRSF PIRSF000770 15 260 3.1E-32 T 29-03-2018 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 Pfam PF04539 Sigma-70 region 3 125 176 2.5E-8 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 SUPERFAMILY SSF88659 115 191 1.31E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 SUPERFAMILY SSF88659 176 258 1.83E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 228 254 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 67 80 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 Gene3D G3DSA:1.10.601.10 5 111 2.6E-32 T 29-03-2018 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 Gene3D G3DSA:1.10.1270.10 176 260 1.5E-16 T 29-03-2018 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 SUPERFAMILY SSF88946 12 111 2.35E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 91 99 1.8E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 211 223 1.8E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 228 243 1.8E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 243 254 1.8E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 67 80 1.8E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07630 f6e1406933a2065a5eb005fa64fe0d8d 260 Pfam PF04542 Sigma-70 region 2 43 111 4.7E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 SMART SM00116 258 306 3.9E-10 T 29-03-2018 IPR000644 CBS domain CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 SMART SM00116 318 366 4.5E-8 T 29-03-2018 IPR000644 CBS domain CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 Pfam PF00571 CBS domain 311 363 1.6E-7 T 29-03-2018 IPR000644 CBS domain CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 Pfam PF00571 CBS domain 251 297 5.5E-9 T 29-03-2018 IPR000644 CBS domain CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 13 371 3.5E-183 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 SMART SM00382 27 213 9.2E-22 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 Gene3D G3DSA:3.10.580.10 264 377 1.6E-22 T 29-03-2018 CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 Pfam PF00005 ABC transporter 19 163 1.9E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 Gene3D G3DSA:3.40.50.300 1 263 2.3E-81 T 29-03-2018 CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 SUPERFAMILY SSF54631 250 374 1.3E-24 T 29-03-2018 CXR48_RS15930 9371c0e650713c56f0a2e1c43d656a44 379 SUPERFAMILY SSF52540 1 240 2.51E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16020 90febcc635a32d3bcf19300cfe18856b 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 41.454 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16020 90febcc635a32d3bcf19300cfe18856b 253 SUPERFAMILY SSF51351 1 248 8.64E-94 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16020 90febcc635a32d3bcf19300cfe18856b 253 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.6E-57 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16020 90febcc635a32d3bcf19300cfe18856b 253 Gene3D G3DSA:3.20.20.70 1 253 1.1E-102 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS16020 90febcc635a32d3bcf19300cfe18856b 253 Pfam PF00121 Triosephosphate isomerase 5 246 4.4E-95 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16020 90febcc635a32d3bcf19300cfe18856b 253 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS10390 28c7052618a854c3df5b65e60e2efb10 303 Gene3D G3DSA:3.40.50.300 41 286 6.1E-13 T 29-03-2018 CXR48_RS10390 28c7052618a854c3df5b65e60e2efb10 303 SMART SM00382 153 278 2.1E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS10390 28c7052618a854c3df5b65e60e2efb10 303 SUPERFAMILY SSF52540 138 277 5.53E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10390 28c7052618a854c3df5b65e60e2efb10 303 Pfam PF01695 IstB-like ATP binding protein 153 264 3.7E-8 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 Gene3D G3DSA:3.40.50.720 1 252 9.5E-78 T 29-03-2018 CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 SUPERFAMILY SSF51735 5 252 7.73E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 251 4.5E-72 T 29-03-2018 CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.9E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.9E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.9E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.9E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.9E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17840 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.9E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 791 0.0 T 29-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Gene3D G3DSA:3.50.50.60 248 309 9.1E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Gene3D G3DSA:3.50.50.60 102 241 3.5E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 SUPERFAMILY SSF56014 627 793 2.62E-48 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.2E-14 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.2E-14 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 1.2E-14 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 1.2E-14 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00397 Sirohaem Fe-binding site signature 673 691 1.5E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00397 Sirohaem Fe-binding site signature 630 648 1.5E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Gene3D G3DSA:3.30.413.10 625 800 8.2E-39 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PIRSF PIRSF037149 1 805 0.0 T 29-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 SUPERFAMILY SSF55124 514 635 5.23E-24 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.3E-23 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.3E-23 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.3E-23 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.3E-23 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.3E-23 T 29-03-2018 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Gene3D G3DSA:3.50.50.60 13 101 3.2E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 SUPERFAMILY SSF51905 4 191 2.29E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 282 7.2E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 SUPERFAMILY SSF51905 143 306 1.92E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 556 618 1.0E-13 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 626 762 5.0E-26 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Pfam PF04324 BFD-like [2Fe-2S] binding domain 416 465 2.0E-13 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Pfam PF04324 BFD-like [2Fe-2S] binding domain 481 530 2.5E-12 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CXR48_RS01730 22672a358ff61abccba6170e3aa76831 805 Gene3D G3DSA:3.90.480.10 398 621 2.9E-15 T 29-03-2018 CXR48_RS09780 29d711455a9940ed8db497b8ee1bde4d 473 Gene3D G3DSA:3.20.20.70 115 326 7.3E-20 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS09780 29d711455a9940ed8db497b8ee1bde4d 473 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 23 427 2.2E-189 T 29-03-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 CXR48_RS09780 29d711455a9940ed8db497b8ee1bde4d 473 TIGRFAM TIGR00238 TIGR00238: KamA family protein 13 342 3.7E-152 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CXR48_RS09780 29d711455a9940ed8db497b8ee1bde4d 473 PIRSF PIRSF004911 2 399 4.7E-158 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CXR48_RS09780 29d711455a9940ed8db497b8ee1bde4d 473 Pfam PF12544 Lysine-2,3-aminomutase 321 447 4.3E-60 T 29-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain CXR48_RS09780 29d711455a9940ed8db497b8ee1bde4d 473 SUPERFAMILY SSF102114 114 359 5.23E-33 T 29-03-2018 CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 Gene3D G3DSA:3.10.350.10 165 236 1.8E-17 T 29-03-2018 CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 SUPERFAMILY SSF47090 243 313 7.85E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 SUPERFAMILY SSF55846 7 158 1.12E-46 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 SMART SM00644 15 153 1.9E-42 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 Pfam PF01476 LysM domain 179 221 3.0E-14 T 29-03-2018 IPR018392 LysM domain CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 Gene3D G3DSA:1.10.101.10 243 317 1.2E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 Gene3D G3DSA:3.40.80.10 3 162 6.0E-38 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 SUPERFAMILY SSF54106 178 221 2.35E-10 T 29-03-2018 IPR018392 LysM domain CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 24 142 5.0E-18 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 SMART SM00257 178 222 1.3E-15 T 29-03-2018 IPR018392 LysM domain CXR48_RS06170 a35a3f2889181fd5ff703a2de716e5cc 317 Pfam PF01471 Putative peptidoglycan binding domain 252 312 3.1E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS15640 d836336b9437cafbb2198b995d68b987 265 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 44 261 1.9E-65 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CXR48_RS15640 d836336b9437cafbb2198b995d68b987 265 SUPERFAMILY SSF53850 38 263 2.86E-67 T 29-03-2018 CXR48_RS15640 d836336b9437cafbb2198b995d68b987 265 Gene3D G3DSA:3.40.190.10 33 132 2.4E-16 T 29-03-2018 CXR48_RS15640 d836336b9437cafbb2198b995d68b987 265 Gene3D G3DSA:3.40.190.10 133 225 2.2E-39 T 29-03-2018 CXR48_RS15640 d836336b9437cafbb2198b995d68b987 265 PIRSF PIRSF004846 2 265 1.0E-88 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CXR48_RS15640 d836336b9437cafbb2198b995d68b987 265 Pfam PF13531 Bacterial extracellular solute-binding protein 39 262 3.4E-52 T 29-03-2018 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 368 1.1E-35 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 Gene3D G3DSA:3.40.120.10 2 157 1.7E-44 T 29-03-2018 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 Gene3D G3DSA:3.40.120.10 158 262 5.6E-26 T 29-03-2018 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 3.9E-43 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 SUPERFAMILY SSF55957 357 446 2.22E-27 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 5.4E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 5.4E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 5.4E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 45.235 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 1.7E-187 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 9.8E-16 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 SUPERFAMILY SSF53738 157 256 1.37E-26 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 SUPERFAMILY SSF53738 3 180 1.81E-46 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 Gene3D G3DSA:3.40.120.10 263 373 3.2E-36 T 29-03-2018 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 SUPERFAMILY SSF53738 257 366 8.83E-33 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 1.4E-19 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS01105 4fda3bbe2aaa9526467f924a532556bf 448 Gene3D G3DSA:3.30.310.50 374 446 2.5E-23 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS00215 57fb4df3e607acf41ec007b616eb344f 146 Pfam PF03885 Protein of unknown function (DUF327) 13 145 7.0E-38 T 29-03-2018 IPR005585 Protein of unknown function DUF327 CXR48_RS00215 57fb4df3e607acf41ec007b616eb344f 146 SUPERFAMILY SSF158397 28 146 4.84E-33 T 29-03-2018 CXR48_RS00215 57fb4df3e607acf41ec007b616eb344f 146 Gene3D G3DSA:1.20.120.490 28 145 5.7E-34 T 29-03-2018 IPR024042 Hypothetical protein TM1646-like domain CXR48_RS01900 488b8f0d851e53b8bf95045a41957828 263 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 55 68 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CXR48_RS01900 488b8f0d851e53b8bf95045a41957828 263 Gene3D G3DSA:3.40.190.10 151 263 1.5E-15 T 29-03-2018 CXR48_RS01900 488b8f0d851e53b8bf95045a41957828 263 Gene3D G3DSA:3.40.190.10 30 150 2.4E-34 T 29-03-2018 CXR48_RS01900 488b8f0d851e53b8bf95045a41957828 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 255 5.0E-60 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS01900 488b8f0d851e53b8bf95045a41957828 263 SMART SM00062 33 256 4.8E-78 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS01900 488b8f0d851e53b8bf95045a41957828 263 SUPERFAMILY SSF53850 1 257 4.66E-66 T 29-03-2018 CXR48_RS13905 850261b7344077a8afd5d8abe9eb8dcd 463 Gene3D G3DSA:3.30.70.360 204 283 4.1E-9 T 29-03-2018 CXR48_RS13905 850261b7344077a8afd5d8abe9eb8dcd 463 Gene3D G3DSA:3.40.630.10 4 191 1.4E-27 T 29-03-2018 CXR48_RS13905 850261b7344077a8afd5d8abe9eb8dcd 463 SUPERFAMILY SSF53187 10 184 3.83E-68 T 29-03-2018 CXR48_RS13905 850261b7344077a8afd5d8abe9eb8dcd 463 SUPERFAMILY SSF53187 380 462 3.83E-68 T 29-03-2018 CXR48_RS13905 850261b7344077a8afd5d8abe9eb8dcd 463 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 11 458 7.9E-173 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CXR48_RS13905 850261b7344077a8afd5d8abe9eb8dcd 463 SUPERFAMILY SSF55031 184 366 1.21E-50 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS13905 850261b7344077a8afd5d8abe9eb8dcd 463 Gene3D G3DSA:3.30.70.360 284 368 2.2E-25 T 29-03-2018 CXR48_RS13905 850261b7344077a8afd5d8abe9eb8dcd 463 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 114 152 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CXR48_RS13905 850261b7344077a8afd5d8abe9eb8dcd 463 Pfam PF01546 Peptidase family M20/M25/M40 84 459 3.0E-35 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS12165 2daa1ad3ad991252349c1de4b6bccb49 710 SUPERFAMILY SSF109604 499 658 3.77E-15 T 29-03-2018 CXR48_RS12165 2daa1ad3ad991252349c1de4b6bccb49 710 Gene3D G3DSA:1.10.3210.10 444 681 9.8E-34 T 29-03-2018 CXR48_RS12165 2daa1ad3ad991252349c1de4b6bccb49 710 Pfam PF01966 HD domain 500 641 2.1E-19 T 29-03-2018 IPR006674 HD domain CXR48_RS12165 2daa1ad3ad991252349c1de4b6bccb49 710 TIGRFAM TIGR00277 HDIG: HDIG domain 497 595 3.2E-29 T 29-03-2018 IPR006675 HDIG domain CXR48_RS12165 2daa1ad3ad991252349c1de4b6bccb49 710 SMART SM00471 496 651 1.0E-11 T 29-03-2018 IPR003607 HD/PDEase domain CXR48_RS12165 2daa1ad3ad991252349c1de4b6bccb49 710 Pfam PF07697 7TM-HD extracellular 53 269 6.1E-39 T 29-03-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain CXR48_RS12165 2daa1ad3ad991252349c1de4b6bccb49 710 Pfam PF07698 7TM receptor with intracellular HD hydrolase 276 475 1.3E-51 T 29-03-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 Gene3D G3DSA:3.40.228.10 370 531 4.3E-9 T 29-03-2018 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 SUPERFAMILY SSF53706 12 556 1.7E-160 T 29-03-2018 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 418 435 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 Pfam PF01568 Molydopterin dinucleotide binding domain 566 667 7.2E-17 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 11 63 2.4E-16 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 SUPERFAMILY SSF50692 558 682 2.03E-27 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 Gene3D G3DSA:2.20.25.90 2 68 8.8E-18 T 29-03-2018 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 SMART SM00926 9 64 6.0E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 Gene3D G3DSA:2.40.40.20 551 687 3.2E-25 T 29-03-2018 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 Gene3D G3DSA:3.40.228.10 155 351 4.2E-62 T 29-03-2018 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 Gene3D G3DSA:3.40.50.740 69 154 3.8E-13 T 29-03-2018 CXR48_RS09385 1d837e76da15fd05d9cf1548e61a7667 687 Pfam PF00384 Molybdopterin oxidoreductase 67 472 2.0E-62 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS07900 89faf669937cd67911d268ed8e655a01 220 Pfam PF03315 Serine dehydratase beta chain 5 73 9.5E-13 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CXR48_RS07900 89faf669937cd67911d268ed8e655a01 220 Gene3D G3DSA:3.30.70.260 147 219 5.1E-14 T 29-03-2018 CXR48_RS07900 89faf669937cd67911d268ed8e655a01 220 SUPERFAMILY SSF143548 19 137 3.01E-32 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CXR48_RS07900 89faf669937cd67911d268ed8e655a01 220 PIRSF PIRSF036692 1 220 2.7E-103 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CXR48_RS07900 89faf669937cd67911d268ed8e655a01 220 Pfam PF01842 ACT domain 149 210 1.1E-8 T 29-03-2018 IPR002912 ACT domain CXR48_RS07900 89faf669937cd67911d268ed8e655a01 220 Gene3D G3DSA:3.30.1330.90 20 145 3.0E-27 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CXR48_RS07900 89faf669937cd67911d268ed8e655a01 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 1.2E-110 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CXR48_RS07900 89faf669937cd67911d268ed8e655a01 220 SUPERFAMILY SSF55021 137 217 7.63E-16 T 29-03-2018 CXR48_RS16680 1d8839384f04a1dff8598222d8d50a28 160 SUPERFAMILY SSF140566 2 129 1.12E-18 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CXR48_RS16680 1d8839384f04a1dff8598222d8d50a28 160 Pfam PF05130 FlgN protein 1 144 2.5E-26 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CXR48_RS16680 1d8839384f04a1dff8598222d8d50a28 160 Gene3D G3DSA:1.20.58.300 2 131 1.6E-25 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF47336 4 129 7.98E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00826 2706 2869 2.4E-17 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF53901 519 539 5.31E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF53901 114 483 5.31E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3154 3341 2.5E-48 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1221 1401 2.4E-29 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2456 2559 4.7E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 494 581 6.4E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3920 4027 8.0E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF08659 KR domain 3154 3340 4.9E-53 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF08659 KR domain 1221 1399 2.3E-40 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF51735 3150 3391 5.71E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 373 490 7.8E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2335 2452 2.2E-37 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3792 3916 3.9E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF53901 2490 2508 5.31E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF53901 2093 2445 5.31E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:1.10.1200.10 1868 1970 5.2E-13 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:1.10.1200.10 3 115 4.5E-9 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:1.10.1200.10 3417 3527 9.7E-16 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF53335 1627 1812 1.62E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00823 Phosphopantetheine attachment site 3422 3493 2.1E-11 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00823 Phosphopantetheine attachment site 1982 2051 6.7E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00823 Phosphopantetheine attachment site 5 75 9.8E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00823 Phosphopantetheine attachment site 1873 1943 2.0E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF47336 1873 1944 1.83E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF14765 Polyketide synthase dehydratase 2706 2980 4.0E-57 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF14765 Polyketide synthase dehydratase 718 987 4.0E-42 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3697 3713 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.40.50.150 1609 1833 6.7E-19 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF00550 Phosphopantetheine attachment site 1984 2048 1.9E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF00550 Phosphopantetheine attachment site 1877 1938 7.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF00550 Phosphopantetheine attachment site 3424 3489 1.6E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF00550 Phosphopantetheine attachment site 7 71 9.5E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1899 1914 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2094 2327 7.6E-80 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3536 3784 8.7E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 117 365 6.3E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:1.10.1200.10 1971 2056 7.1E-11 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF53901 3533 3909 8.05E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF53901 3951 3970 8.05E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Pfam PF08242 Methyltransferase domain 1655 1759 4.8E-15 T 29-03-2018 IPR013217 Methyltransferase type 12 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.40.50.720 3147 3414 1.9E-47 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.40.50.720 1215 1465 2.8E-33 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.40.47.10 380 542 3.7E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.40.47.10 2343 2512 1.4E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.40.47.10 3800 3973 8.9E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00825 Beta-ketoacyl synthase 2095 2514 1.4E-184 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00825 Beta-ketoacyl synthase 119 544 2.2E-194 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM00825 Beta-ketoacyl synthase 3538 3975 3.4E-200 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF47336 3420 3550 9.42E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 278 294 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2240 2256 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.40.47.10 116 376 3.3E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.40.47.10 3528 3796 5.8E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.40.47.10 2087 2339 1.5E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF51735 1219 1443 6.61E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.10.129.10 720 837 7.8E-13 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 Gene3D G3DSA:3.10.129.10 2709 2831 4.0E-19 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF51735 1005 1205 1.61E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SUPERFAMILY SSF47336 1983 2051 1.28E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM01294 6 71 6.5E-4 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 SMART SM01294 3423 3489 5.7E-6 T 29-03-2018 CXR48_RS11360 3202e97e0d901c38a9631a92d6bfafbb 4193 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2008 2023 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS15620 88fc35cda42bb09f5ae8f3902c1ea5ca 46 TIGRFAM TIGR02863 spore_sspJ: small, acid-soluble spore protein, SspJ family 1 46 4.1E-26 T 29-03-2018 IPR014220 Small acid-soluble spore protein, SspJ CXR48_RS15620 88fc35cda42bb09f5ae8f3902c1ea5ca 46 Pfam PF09575 Small spore protein J (Spore_SspJ) 1 46 1.2E-24 T 29-03-2018 IPR014220 Small acid-soluble spore protein, SspJ CXR48_RS09370 0a88bfa442f9a3d1b46089b2c923f80c 415 Pfam PF07690 Major Facilitator Superfamily 15 251 9.5E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS09370 0a88bfa442f9a3d1b46089b2c923f80c 415 Pfam PF07690 Major Facilitator Superfamily 262 392 7.7E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS09370 0a88bfa442f9a3d1b46089b2c923f80c 415 TIGRFAM TIGR00897 2A0118: polyol permease 1 398 2.3E-196 T 29-03-2018 IPR004748 Polyol permease GO:0005215|GO:0006810|GO:0016021 CXR48_RS09370 0a88bfa442f9a3d1b46089b2c923f80c 415 Gene3D G3DSA:1.20.1250.20 8 206 6.2E-23 T 29-03-2018 CXR48_RS09370 0a88bfa442f9a3d1b46089b2c923f80c 415 SUPERFAMILY SSF103473 8 397 8.37E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS09370 0a88bfa442f9a3d1b46089b2c923f80c 415 Gene3D G3DSA:1.20.1250.20 208 409 1.5E-20 T 29-03-2018 CXR48_RS09670 ae76da89a411bd8a8f6a82dbba3da357 202 Pfam PF00881 Nitroreductase family 9 182 7.0E-29 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CXR48_RS09670 ae76da89a411bd8a8f6a82dbba3da357 202 Gene3D G3DSA:3.40.109.10 3 202 1.2E-41 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS09670 ae76da89a411bd8a8f6a82dbba3da357 202 SUPERFAMILY SSF55469 1 201 6.28E-52 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS11020 455eff6f822e20f866fcfff8d7b82613 173 SUPERFAMILY SSF140663 2 128 4.05E-33 T 29-03-2018 IPR023203 TTHA0068-like domain CXR48_RS11020 455eff6f822e20f866fcfff8d7b82613 173 Pfam PF03745 Domain of unknown function (DUF309) 9 66 3.6E-22 T 29-03-2018 IPR005500 Protein of unknown function DUF309 CXR48_RS11020 455eff6f822e20f866fcfff8d7b82613 173 Gene3D G3DSA:1.10.3450.10 1 134 1.0E-37 T 29-03-2018 IPR023203 TTHA0068-like domain CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 373 4.4E-28 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 3 124 1.2E-40 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 Pfam PF12631 MnmE helical domain 127 456 8.5E-60 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 2 459 34.493 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 SUPERFAMILY SSF52540 202 375 4.99E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 SUPERFAMILY SSF52540 78 167 4.99E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 Gene3D G3DSA:3.30.1360.120 1 125 1.2E-44 T 29-03-2018 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 9 459 1.2E-131 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 Pfam PF01926 50S ribosome-binding GTPase 225 336 1.3E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 PRINTS PR00449 Transforming protein P21 ras signature 222 243 8.6E-6 T 29-03-2018 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 PRINTS PR00449 Transforming protein P21 ras signature 262 284 8.6E-6 T 29-03-2018 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 PRINTS PR00449 Transforming protein P21 ras signature 326 339 8.6E-6 T 29-03-2018 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 SUPERFAMILY SSF116878 125 225 8.76E-51 T 29-03-2018 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 SUPERFAMILY SSF116878 384 459 8.76E-51 T 29-03-2018 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 Gene3D G3DSA:1.20.120.430 126 287 1.5E-32 T 29-03-2018 CXR48_RS19415 dd8639052229419e447b72dae7a4ec40 459 Gene3D G3DSA:1.20.120.430 288 459 8.9E-31 T 29-03-2018 CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 Pfam PF04055 Radical SAM superfamily 215 386 1.4E-33 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 Gene3D G3DSA:3.80.30.20 209 443 3.1E-57 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 SUPERFAMILY SSF102114 198 434 2.35E-63 T 29-03-2018 CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 66 503 74.685 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 Pfam PF01938 TRAM domain 441 500 1.2E-16 T 29-03-2018 IPR002792 TRAM domain CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 Pfam PF00919 Uncharacterized protein family UPF0004 67 168 1.7E-29 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 67 501 5.1E-221 T 29-03-2018 CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 SMART SM00729 211 429 6.3E-63 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 215 235 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CXR48_RS08485 7e25125d332e407348a088a5ff1f6d2f 509 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 67 499 2.0E-167 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CXR48_RS05525 41649a21c0ca249f00ee6c521a7e8d27 61 Pfam PF11151 Protein of unknown function (DUF2929) 2 55 4.6E-17 T 29-03-2018 IPR021324 Protein of unknown function DUF2929 CXR48_RS00105 9a15b5b171f7f30033bdeefabec20809 217 Pfam PF01712 Deoxynucleoside kinase 12 211 9.2E-67 T 29-03-2018 IPR031314 Deoxynucleoside kinase domain CXR48_RS00105 9a15b5b171f7f30033bdeefabec20809 217 Gene3D G3DSA:3.40.50.300 6 215 5.3E-42 T 29-03-2018 CXR48_RS00105 9a15b5b171f7f30033bdeefabec20809 217 SUPERFAMILY SSF52540 8 212 1.03E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00105 9a15b5b171f7f30033bdeefabec20809 217 PIRSF PIRSF000705 1 217 3.2E-66 T 29-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CXR48_RS10090 d4d4c93025f2abd4554cd96b040af7c8 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.5E-29 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS10090 d4d4c93025f2abd4554cd96b040af7c8 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CXR48_RS10090 d4d4c93025f2abd4554cd96b040af7c8 66 Gene3D G3DSA:2.40.50.140 1 66 2.7E-27 T 29-03-2018 CXR48_RS10090 d4d4c93025f2abd4554cd96b040af7c8 66 SUPERFAMILY SSF50249 1 65 9.04E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS10090 d4d4c93025f2abd4554cd96b040af7c8 66 SMART SM00357 3 66 2.0E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CXR48_RS10090 d4d4c93025f2abd4554cd96b040af7c8 66 PRINTS PR00050 Cold shock protein signature 39 57 5.0E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS10090 d4d4c93025f2abd4554cd96b040af7c8 66 PRINTS PR00050 Cold shock protein signature 24 33 5.0E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS10090 d4d4c93025f2abd4554cd96b040af7c8 66 PRINTS PR00050 Cold shock protein signature 4 19 5.0E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS10090 d4d4c93025f2abd4554cd96b040af7c8 66 PIRSF PIRSF002599 1 66 4.7E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CXR48_RS07655 84e43ccf82cc43b50ced8bc40f835578 230 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CXR48_RS07655 84e43ccf82cc43b50ced8bc40f835578 230 SUPERFAMILY SSF51419 3 222 1.2E-72 T 29-03-2018 IPR029066 PLP-binding barrel CXR48_RS07655 84e43ccf82cc43b50ced8bc40f835578 230 Gene3D G3DSA:3.20.20.10 2 230 2.9E-59 T 29-03-2018 IPR029066 PLP-binding barrel CXR48_RS07655 84e43ccf82cc43b50ced8bc40f835578 230 Pfam PF01168 Alanine racemase, N-terminal domain 8 225 1.3E-22 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS07655 84e43ccf82cc43b50ced8bc40f835578 230 PIRSF PIRSF004848 1 226 2.4E-69 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CXR48_RS07655 84e43ccf82cc43b50ced8bc40f835578 230 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 6 223 1.8E-52 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 5.5E-128 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 Gene3D G3DSA:1.10.580.10 11 260 9.0E-86 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 SUPERFAMILY SSF48256 2 371 1.83E-135 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 PIRSF PIRSF001369 1 372 7.5E-161 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 8.7E-171 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 Gene3D G3DSA:1.10.580.10 298 351 9.4E-11 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 PRINTS PR00143 Citrate synthase signature 123 136 1.5E-43 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 PRINTS PR00143 Citrate synthase signature 172 187 1.5E-43 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 PRINTS PR00143 Citrate synthase signature 304 320 1.5E-43 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 PRINTS PR00143 Citrate synthase signature 324 338 1.5E-43 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 PRINTS PR00143 Citrate synthase signature 194 222 1.5E-43 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS13470 1cb8ca3e84ee6ce112b0adc77b6cc018 372 PRINTS PR00143 Citrate synthase signature 247 267 1.5E-43 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS18445 7e17a0fb3a15dab1151243f77ed37ccd 293 Pfam PF13649 Methyltransferase domain 104 191 1.9E-11 T 29-03-2018 CXR48_RS18445 7e17a0fb3a15dab1151243f77ed37ccd 293 PIRSF PIRSF018249 6 291 1.1E-74 T 29-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 CXR48_RS18445 7e17a0fb3a15dab1151243f77ed37ccd 293 Gene3D G3DSA:3.40.50.150 17 290 1.0E-44 T 29-03-2018 CXR48_RS18445 7e17a0fb3a15dab1151243f77ed37ccd 293 SUPERFAMILY SSF53335 21 270 5.16E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS15240 a17259b4b9dd365ae5d711dfb7c392d3 371 SUPERFAMILY SSF54373 224 312 2.22E-14 T 29-03-2018 CXR48_RS15240 a17259b4b9dd365ae5d711dfb7c392d3 371 Gene3D G3DSA:3.50.50.60 267 369 1.7E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS15240 a17259b4b9dd365ae5d711dfb7c392d3 371 Pfam PF01266 FAD dependent oxidoreductase 5 351 1.0E-52 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CXR48_RS15240 a17259b4b9dd365ae5d711dfb7c392d3 371 SUPERFAMILY SSF51905 312 366 1.81E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS15240 a17259b4b9dd365ae5d711dfb7c392d3 371 SUPERFAMILY SSF51905 4 221 1.81E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS15240 a17259b4b9dd365ae5d711dfb7c392d3 371 Gene3D G3DSA:3.50.50.60 3 266 2.1E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 Gene3D G3DSA:1.20.1250.20 254 553 2.7E-34 T 29-03-2018 CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 102 122 1.1E-8 T 29-03-2018 CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 1.1E-8 T 29-03-2018 CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 1.1E-8 T 29-03-2018 CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 1.1E-8 T 29-03-2018 CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 SUPERFAMILY SSF103473 197 414 1.11E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 SUPERFAMILY SSF103473 513 547 1.11E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 Gene3D G3DSA:1.20.1250.20 2 196 3.1E-34 T 29-03-2018 CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 535 3.2E-87 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 SUPERFAMILY SSF103473 4 189 3.79E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS14085 3dbcb207f1a350ff332ab9afd1970ba3 555 Pfam PF07690 Major Facilitator Superfamily 12 404 2.4E-49 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS14945 7c1a5744f11ee28c5e90632c4ee37781 41 SUPERFAMILY SSF57938 7 38 6.54E-6 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CXR48_RS14945 7c1a5744f11ee28c5e90632c4ee37781 41 Pfam PF17302 Family of unknown function (DUF5351) 11 39 3.7E-18 T 29-03-2018 IPR035272 Protein of unknown function DUF5351 CXR48_RS14945 7c1a5744f11ee28c5e90632c4ee37781 41 Gene3D G3DSA:2.10.230.10 1 41 9.5E-5 T 29-03-2018 CXR48_RS14945 7c1a5744f11ee28c5e90632c4ee37781 41 ProDom PD049837 YUIA BH3406 1 39 6.0E-11 T 29-03-2018 IPR035272 Protein of unknown function DUF5351 CXR48_RS13250 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 457 7.0E-74 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CXR48_RS13250 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Gene3D G3DSA:1.10.45.10 418 457 3.4E-16 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CXR48_RS13250 a7cb4f5b07de74b5ccb65b7ec91d040c 470 SUPERFAMILY SSF55103 220 460 1.64E-65 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CXR48_RS13250 a7cb4f5b07de74b5ccb65b7ec91d040c 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 7.7E-189 T 29-03-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 CXR48_RS13250 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Pfam PF01565 FAD binding domain 41 180 1.2E-42 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CXR48_RS13250 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Gene3D G3DSA:3.30.43.10 3 93 2.0E-21 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CXR48_RS13250 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Gene3D G3DSA:3.30.465.10 94 239 8.7E-45 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS13250 a7cb4f5b07de74b5ccb65b7ec91d040c 470 SUPERFAMILY SSF56176 6 217 9.81E-73 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS04060 2109f624cbaf70978a63aec07664afdd 90 Gene3D G3DSA:3.30.370.10 1 90 1.7E-26 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CXR48_RS04060 2109f624cbaf70978a63aec07664afdd 90 SUPERFAMILY SSF52038 4 87 2.88E-27 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CXR48_RS04060 2109f624cbaf70978a63aec07664afdd 90 Pfam PF01337 Barstar (barnase inhibitor) 6 81 4.8E-23 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 Gene3D G3DSA:3.30.70.20 96 191 1.2E-4 T 29-03-2018 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 42.397 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 SMART SM00567 E-Z type HEAT repeats 298 327 270.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 SMART SM00567 E-Z type HEAT repeats 330 359 2.3E-6 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 Pfam PF13646 HEAT repeats 300 368 2.3E-12 T 29-03-2018 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 SUPERFAMILY SSF54862 164 250 7.95E-14 T 29-03-2018 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 Gene3D G3DSA:1.25.40.70 261 371 8.2E-9 T 29-03-2018 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 Pfam PF13484 4Fe-4S double cluster binding domain 188 250 1.8E-17 T 29-03-2018 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 8.7E-18 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 Gene3D G3DSA:3.30.70.20 192 251 2.6E-8 T 29-03-2018 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 SUPERFAMILY SSF48371 265 372 8.64E-12 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CXR48_RS04440 e57e550c4740b5b26ee3de641c3365d9 386 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 342 9.9E-126 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CXR48_RS14005 754e7a2515e64ea18fcd37ca2760f308 261 SMART SM00086 89 129 2.2E-6 T 29-03-2018 IPR001610 PAC motif CXR48_RS14005 754e7a2515e64ea18fcd37ca2760f308 261 SUPERFAMILY SSF52091 148 258 1.06E-12 T 29-03-2018 IPR002645 STAS domain CXR48_RS14005 754e7a2515e64ea18fcd37ca2760f308 261 Gene3D G3DSA:3.30.750.24 144 259 2.6E-10 T 29-03-2018 IPR002645 STAS domain CXR48_RS14005 754e7a2515e64ea18fcd37ca2760f308 261 Pfam PF13426 PAS domain 27 128 1.1E-19 T 29-03-2018 IPR000014 PAS domain CXR48_RS14005 754e7a2515e64ea18fcd37ca2760f308 261 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 134 3.8E-20 T 29-03-2018 IPR000014 PAS domain CXR48_RS14005 754e7a2515e64ea18fcd37ca2760f308 261 SUPERFAMILY SSF55785 21 129 2.27E-24 T 29-03-2018 IPR000014 PAS domain CXR48_RS14005 754e7a2515e64ea18fcd37ca2760f308 261 Pfam PF01740 STAS domain 151 254 1.4E-7 T 29-03-2018 IPR002645 STAS domain CXR48_RS14005 754e7a2515e64ea18fcd37ca2760f308 261 SMART SM00091 14 84 0.0011 T 29-03-2018 IPR000014 PAS domain CXR48_RS14005 754e7a2515e64ea18fcd37ca2760f308 261 Gene3D G3DSA:3.30.450.20 7 142 3.7E-27 T 29-03-2018 CXR48_RS17525 4980f64fe25955615a616d4e251ff517 196 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 37.477 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CXR48_RS17525 4980f64fe25955615a616d4e251ff517 196 SUPERFAMILY SSF52540 8 142 1.91E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS17525 4980f64fe25955615a616d4e251ff517 196 SUPERFAMILY SSF57716 142 193 1.32E-16 T 29-03-2018 CXR48_RS17525 4980f64fe25955615a616d4e251ff517 196 Gene3D G3DSA:3.30.60.20 142 196 5.6E-20 T 29-03-2018 CXR48_RS17525 4980f64fe25955615a616d4e251ff517 196 Pfam PF00265 Thymidine kinase 8 187 1.9E-60 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CXR48_RS17525 4980f64fe25955615a616d4e251ff517 196 Gene3D G3DSA:3.40.50.300 7 141 4.1E-44 T 29-03-2018 CXR48_RS17525 4980f64fe25955615a616d4e251ff517 196 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 29-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CXR48_RS17525 4980f64fe25955615a616d4e251ff517 196 PIRSF PIRSF035805 5 196 1.8E-64 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CXR48_RS17815 3a356ee17369535af951cf3430c2ebec 254 Pfam PF06778 Chlorite dismutase 41 243 3.8E-77 T 29-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CXR48_RS17815 3a356ee17369535af951cf3430c2ebec 254 Gene3D G3DSA:3.30.70.1100 145 250 2.4E-31 T 29-03-2018 CXR48_RS17815 3a356ee17369535af951cf3430c2ebec 254 Gene3D G3DSA:3.30.70.1030 10 142 3.4E-42 T 29-03-2018 CXR48_RS17815 3a356ee17369535af951cf3430c2ebec 254 Hamap MF_01442 Putative heme-dependent peroxidase . 7 254 56.92 T 29-03-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family CXR48_RS17815 3a356ee17369535af951cf3430c2ebec 254 SUPERFAMILY SSF54909 13 253 1.82E-95 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS02920 f8bfc5ac8e3fb69f0d591cf9cb6ecdc5 188 Pfam PF07563 Protein of unknown function (DUF1541) 130 181 5.5E-28 T 29-03-2018 IPR011438 Domain of unknown function DUF1541 CXR48_RS02920 f8bfc5ac8e3fb69f0d591cf9cb6ecdc5 188 Pfam PF07563 Protein of unknown function (DUF1541) 66 117 3.3E-24 T 29-03-2018 IPR011438 Domain of unknown function DUF1541 CXR48_RS02920 f8bfc5ac8e3fb69f0d591cf9cb6ecdc5 188 Gene3D G3DSA:3.40.190.10 1 182 5.8E-5 T 29-03-2018 CXR48_RS05370 8bee59f79f252f1c9a4426a3c29130b7 287 SMART SM00342 196 279 2.7E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS05370 8bee59f79f252f1c9a4426a3c29130b7 287 SUPERFAMILY SSF51215 2 170 1.7E-21 T 29-03-2018 CXR48_RS05370 8bee59f79f252f1c9a4426a3c29130b7 287 Gene3D G3DSA:2.60.120.10 6 238 9.4E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS05370 8bee59f79f252f1c9a4426a3c29130b7 287 SUPERFAMILY SSF46689 183 230 2.91E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS05370 8bee59f79f252f1c9a4426a3c29130b7 287 Gene3D G3DSA:1.10.10.60 239 287 2.2E-13 T 29-03-2018 CXR48_RS05370 8bee59f79f252f1c9a4426a3c29130b7 287 Pfam PF02311 AraC-like ligand binding domain 28 93 6.0E-8 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CXR48_RS05370 8bee59f79f252f1c9a4426a3c29130b7 287 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 233 275 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CXR48_RS05370 8bee59f79f252f1c9a4426a3c29130b7 287 Pfam PF12833 Helix-turn-helix domain 202 280 2.4E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS05370 8bee59f79f252f1c9a4426a3c29130b7 287 SUPERFAMILY SSF46689 232 280 3.4E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS04070 0d5ab020185b622404c3212358b5a033 530 Pfam PF07690 Major Facilitator Superfamily 19 416 3.4E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS04070 0d5ab020185b622404c3212358b5a033 530 SUPERFAMILY SSF103473 489 515 4.84E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS04070 0d5ab020185b622404c3212358b5a033 530 SUPERFAMILY SSF103473 258 425 4.84E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS04070 0d5ab020185b622404c3212358b5a033 530 SUPERFAMILY SSF103473 9 204 4.84E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS04070 0d5ab020185b622404c3212358b5a033 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 77 99 2.7E-5 T 29-03-2018 CXR48_RS04070 0d5ab020185b622404c3212358b5a033 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 2.7E-5 T 29-03-2018 CXR48_RS04070 0d5ab020185b622404c3212358b5a033 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 204 222 2.7E-5 T 29-03-2018 CXR48_RS04070 0d5ab020185b622404c3212358b5a033 530 Gene3D G3DSA:1.20.1250.20 6 201 5.5E-40 T 29-03-2018 CXR48_RS04070 0d5ab020185b622404c3212358b5a033 530 Gene3D G3DSA:1.20.1250.20 268 529 9.2E-27 T 29-03-2018 CXR48_RS03515 7c88809e01ac73701dbb6b69c85059af 229 Gene3D G3DSA:3.30.240.20 82 151 2.2E-22 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CXR48_RS03515 7c88809e01ac73701dbb6b69c85059af 229 Gene3D G3DSA:3.30.240.20 170 226 2.1E-17 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CXR48_RS03515 7c88809e01ac73701dbb6b69c85059af 229 Pfam PF04239 Protein of unknown function (DUF421) 88 204 7.0E-31 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CXR48_RS17250 768eb416b8ebcceb28e11b30a381dd3b 403 ProSitePatterns PS01219 Ammonium transporters signature. 157 182 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CXR48_RS17250 768eb416b8ebcceb28e11b30a381dd3b 403 TIGRFAM TIGR00836 amt: ammonium transporter 5 400 1.1E-145 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CXR48_RS17250 768eb416b8ebcceb28e11b30a381dd3b 403 Pfam PF00909 Ammonium Transporter Family 7 400 2.1E-135 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CXR48_RS17250 768eb416b8ebcceb28e11b30a381dd3b 403 PRINTS PR00342 Rhesus blood group protein signature 101 117 1.3E-6 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CXR48_RS17250 768eb416b8ebcceb28e11b30a381dd3b 403 PRINTS PR00342 Rhesus blood group protein signature 225 247 1.3E-6 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CXR48_RS17250 768eb416b8ebcceb28e11b30a381dd3b 403 PRINTS PR00342 Rhesus blood group protein signature 194 212 1.3E-6 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CXR48_RS17250 768eb416b8ebcceb28e11b30a381dd3b 403 PRINTS PR00342 Rhesus blood group protein signature 280 298 1.3E-6 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CXR48_RS17250 768eb416b8ebcceb28e11b30a381dd3b 403 SUPERFAMILY SSF111352 3 380 3.4E-128 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CXR48_RS17250 768eb416b8ebcceb28e11b30a381dd3b 403 Gene3D G3DSA:1.10.3430.10 1 381 7.7E-135 T 29-03-2018 CXR48_RS18595 aeaf22e8e4b0336c97e2df2cb6aa3047 316 PRINTS PR00116 Arginase signature 122 137 3.2E-6 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18595 aeaf22e8e4b0336c97e2df2cb6aa3047 316 PRINTS PR00116 Arginase signature 236 265 3.2E-6 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18595 aeaf22e8e4b0336c97e2df2cb6aa3047 316 TIGRFAM TIGR01227 hutG: formimidoylglutamase 1 310 5.1E-110 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CXR48_RS18595 aeaf22e8e4b0336c97e2df2cb6aa3047 316 Gene3D G3DSA:3.40.800.10 23 315 1.7E-70 T 29-03-2018 CXR48_RS18595 aeaf22e8e4b0336c97e2df2cb6aa3047 316 Pfam PF00491 Arginase family 38 308 3.0E-63 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18595 aeaf22e8e4b0336c97e2df2cb6aa3047 316 ProSitePatterns PS01053 Arginase family signature. 239 260 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CXR48_RS18595 aeaf22e8e4b0336c97e2df2cb6aa3047 316 PIRSF PIRSF036979 26 314 7.7E-52 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18595 aeaf22e8e4b0336c97e2df2cb6aa3047 316 SUPERFAMILY SSF52768 36 312 3.06E-68 T 29-03-2018 CXR48_RS18930 e06d2fd87ba1e1867c05f27cf0f977e9 157 SUPERFAMILY SSF55729 3 151 7.27E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS18930 e06d2fd87ba1e1867c05f27cf0f977e9 157 Gene3D G3DSA:3.40.630.30 2 156 5.5E-29 T 29-03-2018 CXR48_RS18930 e06d2fd87ba1e1867c05f27cf0f977e9 157 Pfam PF00583 Acetyltransferase (GNAT) family 55 145 1.8E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS06775 6db60ddcfd1d30881b32689697e70641 271 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 219 7.3E-28 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CXR48_RS06775 6db60ddcfd1d30881b32689697e70641 271 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 186 203 - T 29-03-2018 IPR000540 Flagellar motor protein MotA, conserved site CXR48_RS03905 c10e1e9c7467f07c77e4bd559618bb11 277 Gene3D G3DSA:2.30.30.60 116 165 3.3E-9 T 29-03-2018 CXR48_RS03905 c10e1e9c7467f07c77e4bd559618bb11 277 Pfam PF00924 Mechanosensitive ion channel 59 265 3.6E-32 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CXR48_RS03905 c10e1e9c7467f07c77e4bd559618bb11 277 Gene3D G3DSA:3.30.70.100 167 265 1.5E-7 T 29-03-2018 CXR48_RS03905 c10e1e9c7467f07c77e4bd559618bb11 277 SUPERFAMILY SSF82861 15 99 1.83E-9 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CXR48_RS03905 c10e1e9c7467f07c77e4bd559618bb11 277 SUPERFAMILY SSF50182 101 161 5.23E-11 T 29-03-2018 IPR010920 LSM domain CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 Gene3D G3DSA:3.40.50.880 1 191 1.0E-58 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 SUPERFAMILY SSF52317 1 189 6.88E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.5E-7 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.5E-7 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 3.5E-91 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 Pfam PF00117 Glutamine amidotransferase class-I 4 185 8.0E-56 T 29-03-2018 IPR017926 Glutamine amidotransferase CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 4.1E-13 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 4.1E-13 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 4.1E-13 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.0E-35 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.0E-35 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.0E-35 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.0E-35 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.0E-35 T 29-03-2018 CXR48_RS00450 7fed617931af0adf0a19fe6ade7bf74e 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.0E-35 T 29-03-2018 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 SUPERFAMILY SSF51430 8 274 1.7E-95 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 Gene3D G3DSA:3.20.20.100 2 279 4.6E-100 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 PRINTS PR00069 Aldo-keto reductase signature 40 64 1.3E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 PRINTS PR00069 Aldo-keto reductase signature 100 118 1.3E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 PRINTS PR00069 Aldo-keto reductase signature 130 147 1.3E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 PRINTS PR00069 Aldo-keto reductase signature 164 193 1.3E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 PRINTS PR00069 Aldo-keto reductase signature 201 225 1.3E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 Pfam PF00248 Aldo/keto reductase family 31 266 4.1E-52 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 PIRSF PIRSF000097 120 277 1.8E-53 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 PIRSF PIRSF000097 2 123 7.6E-40 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 234 249 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 44 61 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS13425 8368f03c3e81b7a9057955679c4a0187 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 130 147 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 Pfam PF03466 LysR substrate binding domain 88 291 1.3E-44 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 Gene3D G3DSA:3.40.190.10 176 267 1.2E-20 T 29-03-2018 CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 SUPERFAMILY SSF53850 91 291 1.99E-39 T 29-03-2018 CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 SUPERFAMILY SSF46785 1 85 2.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 Gene3D G3DSA:1.10.10.10 1 82 1.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.0E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16990 19c17d227870bdc7d2f7084a7e04f773 302 Gene3D G3DSA:3.40.190.10 88 175 3.0E-21 T 29-03-2018 CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 SUPERFAMILY SSF101386 363 464 1.64E-22 T 29-03-2018 CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 207 4.1E-29 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 SUPERFAMILY SSF101386 233 333 1.74E-25 T 29-03-2018 CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 TIGRFAM TIGR00444 mazG: MazG family protein 240 485 4.8E-116 T 29-03-2018 IPR011551 NTP pyrophosphohydrolase MazG CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 PIRSF PIRSF002845 1 489 5.0E-227 T 29-03-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 Gene3D G3DSA:1.10.287.1080 365 491 1.5E-26 T 29-03-2018 CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 SUPERFAMILY SSF53790 3 258 8.14E-36 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 396 454 6.2E-5 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 256 329 2.2E-28 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 Gene3D G3DSA:1.10.287.1080 233 351 1.2E-39 T 29-03-2018 CXR48_RS00355 57f74d44ffaf8caab47331f5d449276f 491 Gene3D G3DSA:3.40.1010.10 1 121 2.7E-21 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS13390 9ab44f62322b9fbe480001a442b6e2fe 311 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 2.5E-29 T 29-03-2018 IPR009928 Primosomal DnaI, N-terminal CXR48_RS13390 9ab44f62322b9fbe480001a442b6e2fe 311 Gene3D G3DSA:3.40.50.300 108 302 1.6E-22 T 29-03-2018 CXR48_RS13390 9ab44f62322b9fbe480001a442b6e2fe 311 Pfam PF01695 IstB-like ATP binding protein 145 274 4.4E-12 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CXR48_RS13390 9ab44f62322b9fbe480001a442b6e2fe 311 SUPERFAMILY SSF52540 130 274 7.71E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS13390 9ab44f62322b9fbe480001a442b6e2fe 311 SMART SM00382 160 284 1.2E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 8.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 8.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 SUPERFAMILY SSF51735 6 251 2.24E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 1.1E-66 T 29-03-2018 CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 Gene3D G3DSA:3.40.50.720 1 43 9.2E-10 T 29-03-2018 CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 Gene3D G3DSA:3.40.50.720 44 258 6.2E-62 T 29-03-2018 CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02035 e9af24f9daa40004df42a1ad5cff433a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS00590 15608a9026bd9a8bf798e8b9e7241c20 360 SUPERFAMILY SSF143597 22 146 5.1E-30 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CXR48_RS00590 15608a9026bd9a8bf798e8b9e7241c20 360 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 7 357 44.903 T 29-03-2018 IPR023763 DNA integrity scanning protein, DisA CXR48_RS00590 15608a9026bd9a8bf798e8b9e7241c20 360 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 29 141 4.6E-28 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CXR48_RS00590 15608a9026bd9a8bf798e8b9e7241c20 360 Gene3D G3DSA:1.10.150.20 293 357 2.1E-7 T 29-03-2018 CXR48_RS00590 15608a9026bd9a8bf798e8b9e7241c20 360 SUPERFAMILY SSF47781 242 357 1.91E-11 T 29-03-2018 IPR010994 RuvA domain 2-like CXR48_RS00590 15608a9026bd9a8bf798e8b9e7241c20 360 Pfam PF10635 DisA bacterial checkpoint controller linker region 146 284 5.5E-50 T 29-03-2018 IPR018906 DNA integrity scanning, DisA, linker region CXR48_RS00590 15608a9026bd9a8bf798e8b9e7241c20 360 Gene3D G3DSA:3.40.1700.10 10 146 2.2E-27 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 Gene3D G3DSA:3.40.50.1820 7 273 2.3E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 SUPERFAMILY SSF53474 10 272 2.68E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 Pfam PF00561 alpha/beta hydrolase fold 29 136 1.1E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 1.9E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 1.9E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 1.9E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 1.9E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 PRINTS PR00412 Epoxide hydrolase signature 112 125 2.8E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 PRINTS PR00412 Epoxide hydrolase signature 34 52 2.8E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CXR48_RS14625 94ec0d6afdd75767af69eb495a59b617 273 PRINTS PR00412 Epoxide hydrolase signature 249 271 2.8E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CXR48_RS18350 ddd0818013f9b3dd982080aa024f69de 360 PRINTS PR00739 Glycosyl hydrolase family 26 signature 218 241 3.3E-27 T 29-03-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CXR48_RS18350 ddd0818013f9b3dd982080aa024f69de 360 PRINTS PR00739 Glycosyl hydrolase family 26 signature 254 266 3.3E-27 T 29-03-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CXR48_RS18350 ddd0818013f9b3dd982080aa024f69de 360 PRINTS PR00739 Glycosyl hydrolase family 26 signature 116 130 3.3E-27 T 29-03-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CXR48_RS18350 ddd0818013f9b3dd982080aa024f69de 360 PRINTS PR00739 Glycosyl hydrolase family 26 signature 183 200 3.3E-27 T 29-03-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CXR48_RS18350 ddd0818013f9b3dd982080aa024f69de 360 Pfam PF02156 Glycosyl hydrolase family 26 30 348 1.4E-110 T 29-03-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 CXR48_RS18350 ddd0818013f9b3dd982080aa024f69de 360 Gene3D G3DSA:3.20.20.80 18 358 9.0E-81 T 29-03-2018 CXR48_RS18350 ddd0818013f9b3dd982080aa024f69de 360 PIRSF PIRSF018168 1 359 1.1E-149 T 29-03-2018 IPR016714 Mannan endo-1,4-beta-mannosidase GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CXR48_RS18350 ddd0818013f9b3dd982080aa024f69de 360 SUPERFAMILY SSF51445 27 333 3.16E-54 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 945 8.0E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Pfam PF00550 Phosphopantetheine attachment site 973 1034 2.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Gene3D G3DSA:3.40.50.1820 1043 1257 2.9E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 SUPERFAMILY SSF52777 13 192 3.22E-45 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Gene3D G3DSA:3.30.300.30 861 976 8.5E-33 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 SUPERFAMILY SSF53474 1042 1255 1.08E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Pfam PF00501 AMP-binding enzyme 474 866 5.9E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Gene3D G3DSA:3.40.50.980 619 774 1.3E-31 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Gene3D G3DSA:3.30.559.10 3 211 1.0E-36 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 495 890 4.3E-123 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 PRINTS PR00154 AMP-binding signature 620 628 4.5E-5 T 29-03-2018 IPR020459 AMP-binding CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 PRINTS PR00154 AMP-binding signature 608 619 4.5E-5 T 29-03-2018 IPR020459 AMP-binding CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Pfam PF00975 Thioesterase domain 1059 1159 1.5E-21 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Gene3D G3DSA:1.10.1200.10 977 1042 2.5E-18 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Gene3D G3DSA:2.30.38.10 776 856 8.8E-24 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 PIRSF PIRSF001617 908 1059 8.2E-22 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 PIRSF PIRSF001617 196 580 4.7E-10 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 PIRSF PIRSF001617 589 914 6.9E-26 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 ProSitePatterns PS00455 Putative AMP-binding domain signature. 613 624 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 SUPERFAMILY SSF47336 964 1036 4.97E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Gene3D G3DSA:3.40.50.980 465 618 2.2E-41 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 Pfam PF00668 Condensation domain 8 453 1.4E-123 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 SUPERFAMILY SSF56801 434 983 1.16E-143 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 SUPERFAMILY SSF52777 193 442 2.45E-50 T 29-03-2018 CXR48_RS09230 8caa7b035cba6330daeb526ad6d530cf 1267 SMART SM00824 Thioesterase 1061 1202 0.0081 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 Pfam PF01016 Ribosomal L27 protein 10 89 3.6E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 SUPERFAMILY SSF110324 10 91 1.43E-32 T 29-03-2018 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 Gene3D G3DSA:2.40.50.100 28 92 5.0E-29 T 29-03-2018 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 3.2E-41 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 2.0E-17 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 27.333 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 PRINTS PR00063 Ribosomal protein L27 signature 12 36 5.1E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 PRINTS PR00063 Ribosomal protein L27 signature 62 86 5.1E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12865 e92c8534ee9098f939abf170cc50e39a 94 PRINTS PR00063 Ribosomal protein L27 signature 37 61 5.1E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS06250 72f563bafead858c79e3ce098347e905 311 Pfam PF05065 Phage capsid family 20 305 1.7E-22 T 29-03-2018 IPR024455 Phage capsid CXR48_RS06250 72f563bafead858c79e3ce098347e905 311 SUPERFAMILY SSF56563 19 293 2.22E-8 T 29-03-2018 CXR48_RS06250 72f563bafead858c79e3ce098347e905 311 Gene3D G3DSA:3.30.2400.10 40 194 5.0E-9 T 29-03-2018 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF51735 277 485 1.34E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF08659 KR domain 279 456 3.1E-51 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF08659 KR domain 1609 1807 3.9E-39 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SMART SM00825 Beta-ketoacyl synthase 665 1087 6.2E-192 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SMART SM00825 Beta-ketoacyl synthase 1999 2416 5.0E-166 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SMART SM01294 1891 1957 1.7E-4 T 29-03-2018 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Gene3D G3DSA:3.40.50.720 1599 1867 7.5E-36 T 29-03-2018 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Gene3D G3DSA:3.40.50.720 269 525 1.5E-42 T 29-03-2018 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Gene3D G3DSA:1.10.1200.10 1888 1986 1.5E-15 T 29-03-2018 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Gene3D G3DSA:1.10.1200.10 1123 1220 2.4E-9 T 29-03-2018 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Gene3D G3DSA:1.10.1200.10 526 618 5.9E-11 T 29-03-2018 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF00550 Phosphopantetheine attachment site 1146 1210 9.1E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF00550 Phosphopantetheine attachment site 543 606 1.4E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF00550 Phosphopantetheine attachment site 1892 1957 7.4E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF53901 2391 2411 4.53E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF53901 1995 2361 4.53E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1029 1122 1.2E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2368 2414 3.8E-7 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 908 1025 3.9E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2248 2365 2.1E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF47336 1889 1964 3.4E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SMART SM00823 Phosphopantetheine attachment site 541 611 7.0E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SMART SM00823 Phosphopantetheine attachment site 1890 1961 1.0E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SMART SM00823 Phosphopantetheine attachment site 1143 1214 0.14 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 ProSitePatterns PS00012 Phosphopantetheine attachment site. 567 582 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 664 900 2.1E-77 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1998 2240 2.9E-81 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF47336 1141 1220 1.96E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1606 1808 1.7E-28 T 29-03-2018 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 277 458 1.3E-36 T 29-03-2018 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Gene3D G3DSA:3.40.47.10 2255 2414 3.0E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Gene3D G3DSA:3.40.47.10 915 1085 1.5E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF47336 537 612 1.44E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF47336 647 676 1.44E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF53901 663 1018 8.5E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF53901 1063 1082 8.5E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF51735 46 230 2.53E-6 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Gene3D G3DSA:3.40.47.10 1989 2252 1.5E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 Gene3D G3DSA:3.40.47.10 656 912 2.0E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07250 4d69124ebd5f5e30bb3dfd1c21a656f3 2460 SUPERFAMILY SSF51735 1604 1842 2.41E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 466 59.756 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 Pfam PF00330 Aconitase family (aconitate hydratase) 8 457 2.0E-157 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 Gene3D G3DSA:3.30.499.10 326 472 9.2E-51 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 Gene3D G3DSA:3.40.1060.10 155 288 7.5E-45 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 PRINTS PR00415 Aconitase family signature 82 95 1.6E-46 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 PRINTS PR00415 Aconitase family signature 286 300 1.6E-46 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 PRINTS PR00415 Aconitase family signature 195 208 1.6E-46 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 PRINTS PR00415 Aconitase family signature 209 222 1.6E-46 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 PRINTS PR00415 Aconitase family signature 133 148 1.6E-46 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 PRINTS PR00415 Aconitase family signature 119 132 1.6E-46 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 PRINTS PR00415 Aconitase family signature 108 116 1.6E-46 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 PRINTS PR00415 Aconitase family signature 399 412 1.6E-46 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 PRINTS PR00415 Aconitase family signature 343 354 1.6E-46 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 Gene3D G3DSA:3.30.499.10 1 154 4.1E-43 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 SUPERFAMILY SSF53732 2 465 3.66E-168 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13030 15a401f09de8258148c56f7e4616e40e 472 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 2 465 2.7E-268 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 SUPERFAMILY SSF47384 293 353 6.67E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 SMART SM00260 532 671 9.4E-48 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 400 539 3.7E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 537 3.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 518 3.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 456 3.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 494 3.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 SUPERFAMILY SSF50341 539 671 5.49E-33 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Pfam PF07194 P2 response regulator binding domain 169 247 2.8E-26 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 SMART SM00073 3 100 6.7E-42 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Gene3D G3DSA:1.20.120.160 1 148 5.1E-35 T 29-03-2018 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Gene3D G3DSA:1.10.287.560 292 353 7.3E-18 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 SMART SM01231 292 352 3.3E-16 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Gene3D G3DSA:3.30.70.1110 167 246 4.6E-25 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Gene3D G3DSA:3.30.565.10 354 541 2.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Pfam PF01584 CheW-like domain 545 671 2.1E-27 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Gene3D G3DSA:2.30.30.40 618 671 3.2E-21 T 29-03-2018 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Gene3D G3DSA:2.40.50.180 563 617 9.0E-12 T 29-03-2018 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Pfam PF01627 Hpt domain 5 98 7.2E-21 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 SUPERFAMILY SSF55874 354 538 3.27E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 SMART SM00387 397 540 2.7E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 SUPERFAMILY SSF55052 165 247 1.02E-24 T 29-03-2018 IPR015162 CheY binding CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 SUPERFAMILY SSF47226 2 112 1.31E-33 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CXR48_RS08195 5361ed768e7cd0e96ed5b50b05fa17f3 672 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 292 351 2.4E-12 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CXR48_RS04115 4e31b4b48123b1a6bca4c0c9f16889f1 103 Pfam PF08838 Protein of unknown function (DUF1811) 3 101 2.4E-42 T 29-03-2018 IPR014938 Protein of unknown function DUF1811 CXR48_RS04115 4e31b4b48123b1a6bca4c0c9f16889f1 103 Gene3D G3DSA:1.10.287.880 1 50 1.2E-30 T 29-03-2018 CXR48_RS04115 4e31b4b48123b1a6bca4c0c9f16889f1 103 SUPERFAMILY SSF101697 1 103 7.45E-47 T 29-03-2018 IPR014938 Protein of unknown function DUF1811 CXR48_RS04115 4e31b4b48123b1a6bca4c0c9f16889f1 103 Gene3D G3DSA:2.30.30.340 51 102 3.4E-24 T 29-03-2018 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 Gene3D G3DSA:1.20.1250.20 5 195 5.5E-11 T 29-03-2018 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 SUPERFAMILY SSF103473 10 376 6.41E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 71 89 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 160 177 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 349 372 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 94 112 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 210 232 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 133 154 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 286 309 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 247 264 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 10 32 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 45 63 2.0E-142 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 Pfam PF07690 Major Facilitator Superfamily 11 347 7.2E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS17830 dab2a512bc7de7d40e6ba86d4548d531 393 Gene3D G3DSA:1.20.1250.20 196 374 2.1E-6 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 833 849 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2446 2461 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF52777 3547 3709 2.11E-43 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF47336 3451 3522 2.09E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.40.640.10 1678 1823 2.1E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.40.50.980 175 341 7.2E-33 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.40.50.980 3102 3253 1.1E-26 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:1.10.1200.10 3466 3525 2.2E-18 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 924 1041 7.5E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF56801 5 340 9.29E-101 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF56801 368 554 9.29E-101 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.40.47.10 931 1092 1.0E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.30.559.10 3526 3730 8.8E-44 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.30.559.10 2489 2695 2.2E-32 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.30.559.10 1936 2155 2.5E-32 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SMART SM00825 Beta-ketoacyl synthase 671 1094 7.2E-174 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF56801 2914 3472 2.22E-154 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SMART SM00823 Phosphopantetheine attachment site 583 652 0.0016 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SMART SM00823 Phosphopantetheine attachment site 3459 3527 0.02 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SMART SM00823 Phosphopantetheine attachment site 2422 2491 0.038 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SMART SM00823 Phosphopantetheine attachment site 1292 1364 0.0044 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF52777 2137 2373 1.67E-34 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.40.50.980 4 174 7.7E-23 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.40.50.980 2948 3101 4.3E-51 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF52777 1953 2130 1.28E-37 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.40.47.10 661 928 7.6E-69 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3483 3498 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.90.1150.10 1824 1928 3.2E-6 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2978 3375 2.1E-135 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF52777 2679 2943 1.78E-58 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00668 Condensation domain 2506 2937 2.0E-117 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00668 Condensation domain 3544 3971 1.3E-121 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00668 Condensation domain 1949 2389 1.2E-67 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3096 3107 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF47336 2414 2520 6.54E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF47336 578 682 2.49E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF53383 1514 1926 1.58E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:2.30.38.10 3254 3343 1.8E-24 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:2.30.38.10 354 446 1.3E-22 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.90.1150.10 1501 1668 1.8E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1044 1149 4.9E-18 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 1737 1773 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF47336 1286 1385 1.06E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF53901 667 789 4.36E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF53901 816 1035 4.36E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00501 AMP-binding enzyme 2957 3351 3.9E-100 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00501 AMP-binding enzyme 31 452 1.1E-71 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF52777 2505 2692 1.11E-37 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF13193 AMP-binding enzyme C-terminal domain 3359 3432 1.3E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00202 Aminotransferase class-III 1537 1898 2.6E-56 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.30.300.30 449 586 6.2E-14 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.30.300.30 2364 2428 0.39 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:3.30.300.30 3346 3465 4.0E-38 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 669 916 5.4E-68 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00550 Phosphopantetheine attachment site 585 648 9.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00550 Phosphopantetheine attachment site 1295 1360 1.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00550 Phosphopantetheine attachment site 2423 2487 9.8E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Pfam PF00550 Phosphopantetheine attachment site 3461 3522 1.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 SUPERFAMILY SSF52777 3715 3959 2.45E-55 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:1.10.1200.10 2429 2488 4.2E-17 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:1.10.1200.10 1269 1370 2.0E-13 T 29-03-2018 CXR48_RS09105 887ac37b96912af0497934636f6a4518 3982 Gene3D G3DSA:1.10.1200.10 587 660 3.8E-17 T 29-03-2018 CXR48_RS06040 a714a5e958eafd772d456a5418408074 272 Gene3D G3DSA:3.40.50.10090 45 160 4.8E-18 T 29-03-2018 CXR48_RS06040 a714a5e958eafd772d456a5418408074 272 Pfam PF02602 Uroporphyrinogen-III synthase HemD 20 259 5.8E-39 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS06040 a714a5e958eafd772d456a5418408074 272 SUPERFAMILY SSF69618 7 267 1.7E-55 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS06040 a714a5e958eafd772d456a5418408074 272 Gene3D G3DSA:3.40.50.10090 161 269 1.8E-14 T 29-03-2018 CXR48_RS14525 f6b13259e97bff0bbe1c6e8f146c04c2 138 Gene3D G3DSA:2.60.120.460 1 131 5.6E-47 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 CXR48_RS14525 f6b13259e97bff0bbe1c6e8f146c04c2 138 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 5.2E-39 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 CXR48_RS14525 f6b13259e97bff0bbe1c6e8f146c04c2 138 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 3 131 1.3E-56 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 CXR48_RS14525 f6b13259e97bff0bbe1c6e8f146c04c2 138 PIRSF PIRSF004681 1 133 1.9E-37 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 CXR48_RS14525 f6b13259e97bff0bbe1c6e8f146c04c2 138 SUPERFAMILY SSF111038 3 132 1.83E-47 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 CXR48_RS14525 f6b13259e97bff0bbe1c6e8f146c04c2 138 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 95 113 - T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 Gene3D G3DSA:3.30.479.20 57 157 4.8E-24 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 Gene3D G3DSA:3.30.479.20 158 290 6.5E-52 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 SUPERFAMILY SSF54713 152 292 4.97E-52 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 Pfam PF00889 Elongation factor TS 70 274 1.6E-76 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 Gene3D G3DSA:1.10.8.10 1 55 1.8E-24 T 29-03-2018 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 SUPERFAMILY SSF46934 3 54 1.93E-20 T 29-03-2018 IPR009060 UBA-like GO:0005515 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 82.57 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 2.5E-129 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS08230 fd230f57be8abe173cb7cc45b0d6bee0 293 SUPERFAMILY SSF54713 55 144 6.93E-23 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 Gene3D G3DSA:2.40.10.10 71 182 2.2E-30 T 29-03-2018 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 PRINTS PR00834 HtrA/DegQ protease family signature 339 351 5.7E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 PRINTS PR00834 HtrA/DegQ protease family signature 120 132 5.7E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 5.7E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 PRINTS PR00834 HtrA/DegQ protease family signature 248 265 5.7E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 PRINTS PR00834 HtrA/DegQ protease family signature 182 206 5.7E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 PRINTS PR00834 HtrA/DegQ protease family signature 141 161 5.7E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 Pfam PF13180 PDZ domain 293 390 1.0E-21 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 SUPERFAMILY SSF50156 292 390 7.28E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 SUPERFAMILY SSF50494 76 289 3.39E-55 T 29-03-2018 IPR009003 Peptidase S1, PA clan CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 Gene3D G3DSA:2.30.42.10 292 398 4.4E-24 T 29-03-2018 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 SMART SM00228 293 381 2.1E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 Pfam PF13365 Trypsin-like peptidase domain 108 255 1.2E-31 T 29-03-2018 CXR48_RS19005 73ec01a09a65ff2e5faba3a44f5533ad 398 Gene3D G3DSA:2.40.10.10 183 291 2.4E-32 T 29-03-2018 CXR48_RS11710 3249110470872eb3826cbdfbc0b350e5 206 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 3 111 1.7E-37 T 29-03-2018 IPR014245 Sporulation stage III, protein AF CXR48_RS11710 3249110470872eb3826cbdfbc0b350e5 206 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 195 2.0E-40 T 29-03-2018 IPR014245 Sporulation stage III, protein AF CXR48_RS01630 a9e61bbf40a63a80ed06a5424c69e6f5 153 SMART SM00347 31 131 3.5E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS01630 a9e61bbf40a63a80ed06a5424c69e6f5 153 SUPERFAMILY SSF46785 9 149 1.15E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01630 a9e61bbf40a63a80ed06a5424c69e6f5 153 Gene3D G3DSA:1.10.10.10 2 149 3.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01630 a9e61bbf40a63a80ed06a5424c69e6f5 153 Pfam PF01047 MarR family 48 96 3.7E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS18730 4b6ac19667aa07b496b7da32a4e30c36 487 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 481 4.6E-185 T 29-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CXR48_RS18730 4b6ac19667aa07b496b7da32a4e30c36 487 Gene3D G3DSA:3.40.309.10 266 459 1.8E-64 T 29-03-2018 CXR48_RS18730 4b6ac19667aa07b496b7da32a4e30c36 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS18730 4b6ac19667aa07b496b7da32a4e30c36 487 Pfam PF00171 Aldehyde dehydrogenase family 15 477 3.8E-157 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS18730 4b6ac19667aa07b496b7da32a4e30c36 487 Gene3D G3DSA:3.40.605.10 1 265 1.0E-90 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS18730 4b6ac19667aa07b496b7da32a4e30c36 487 SUPERFAMILY SSF53720 4 482 6.02E-153 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS18730 4b6ac19667aa07b496b7da32a4e30c36 487 Hamap MF_01670 Methylmalonate semialdehyde dehydrogenase [acylating] [iolA]. 1 481 73.131 T 29-03-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 6.3E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 Gene3D G3DSA:3.40.1410.10 74 242 3.3E-45 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 Pfam PF07702 UTRA domain 95 233 5.0E-38 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 SUPERFAMILY SSF46785 4 84 6.94E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 SMART SM00866 95 234 2.5E-40 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 SUPERFAMILY SSF64288 62 240 2.36E-53 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 SMART SM00345 15 74 2.4E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16500 fe64f02f07eed6333e59aa4ee4fad962 243 Gene3D G3DSA:1.10.10.10 1 73 1.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 Gene3D G3DSA:3.60.20.10 2 238 9.1E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 SUPERFAMILY SSF53697 244 600 9.0E-97 T 29-03-2018 CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 Gene3D G3DSA:3.40.50.10490 452 598 3.3E-41 T 29-03-2018 CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 Pfam PF13522 Glutamine amidotransferase domain 60 191 2.3E-19 T 29-03-2018 CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 9.2E-231 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 Pfam PF01380 SIS domain 457 582 2.5E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 Pfam PF01380 SIS domain 288 413 1.6E-35 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 Gene3D G3DSA:3.40.50.10490 239 451 1.1E-54 T 29-03-2018 CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 SUPERFAMILY SSF56235 2 234 2.39E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS01110 f7abc5408c857b7cef09ff469a6702c6 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 38.804 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 Hamap MF_00335 Ribonuclease Y [rny]. 4 519 25.917 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 7 519 1.6E-246 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 SMART SM00322 207 274 1.1E-6 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 TIGRFAM TIGR00277 HDIG: HDIG domain 331 408 9.9E-27 T 29-03-2018 IPR006675 HDIG domain CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 SMART SM00471 331 437 5.3E-14 T 29-03-2018 IPR003607 HD/PDEase domain CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 Gene3D G3DSA:3.30.300.20 109 244 1.4E-10 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 Gene3D G3DSA:1.10.3210.10 245 455 4.8E-36 T 29-03-2018 CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 Pfam PF00013 KH domain 212 266 3.4E-6 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 Pfam PF12072 Domain of unknown function (DUF3552) 5 204 5.5E-76 T 29-03-2018 IPR022711 Ribonuclease Y, N-terminal CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 SUPERFAMILY SSF54791 207 303 7.03E-16 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 SUPERFAMILY SSF109604 315 466 2.92E-32 T 29-03-2018 CXR48_RS08460 3261f0676e26284a1fe90f5ad63441ca 519 Pfam PF01966 HD domain 336 427 5.9E-19 T 29-03-2018 IPR006674 HD domain CXR48_RS03125 1297ec090f0c5ef837e59b980acc3b1b 458 Gene3D G3DSA:1.20.1250.20 23 224 1.0E-20 T 29-03-2018 CXR48_RS03125 1297ec090f0c5ef837e59b980acc3b1b 458 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 22 455 2.2E-150 T 29-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CXR48_RS03125 1297ec090f0c5ef837e59b980acc3b1b 458 SUPERFAMILY SSF103473 15 443 5.1E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS03125 1297ec090f0c5ef837e59b980acc3b1b 458 Gene3D G3DSA:1.20.1250.20 225 458 5.6E-20 T 29-03-2018 CXR48_RS03125 1297ec090f0c5ef837e59b980acc3b1b 458 Pfam PF13347 MFS/sugar transport protein 24 442 6.7E-96 T 29-03-2018 CXR48_RS03125 1297ec090f0c5ef837e59b980acc3b1b 458 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 73 98 - T 29-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 SMART SM00354 1 71 2.0E-31 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 SUPERFAMILY SSF53822 61 321 6.42E-54 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 305 2.2E-26 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 Gene3D G3DSA:3.40.50.2300 169 302 4.2E-28 T 29-03-2018 CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 SUPERFAMILY SSF47413 1 58 3.94E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 Gene3D G3DSA:3.40.50.2300 57 168 1.2E-24 T 29-03-2018 CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 Gene3D G3DSA:1.10.260.40 2 56 1.6E-20 T 29-03-2018 CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.1E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.1E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS06860 b523080b2d8481550b6e39aada1eb056 321 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.6E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS14905 6b58560e46ed87f8488efeba812ee13e 289 SUPERFAMILY SSF53474 14 278 1.16E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14905 6b58560e46ed87f8488efeba812ee13e 289 Pfam PF00756 Putative esterase 31 258 8.1E-21 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CXR48_RS14905 6b58560e46ed87f8488efeba812ee13e 289 Gene3D G3DSA:3.40.50.1820 18 281 8.6E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 SUPERFAMILY SSF51735 191 423 1.59E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 191 422 2.1E-77 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 182 204 1.0E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 224 244 1.0E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 102 116 1.0E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 350 361 1.0E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 110 123 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 PIRSF PIRSF000185 12 424 1.6E-170 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 Gene3D G3DSA:3.40.50.10860 43 177 2.9E-49 T 29-03-2018 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 SMART SM00839 193 422 1.1E-92 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 47 173 1.1E-53 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 SUPERFAMILY SSF53223 15 193 2.62E-65 T 29-03-2018 CXR48_RS10890 68c4a54492c83d44aa16dc634aa308b8 424 Gene3D G3DSA:3.40.50.720 191 424 6.4E-78 T 29-03-2018 CXR48_RS03825 afe62312e50bc525cf19663718251bc5 221 SUPERFAMILY SSF55469 8 220 1.22E-54 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS03825 afe62312e50bc525cf19663718251bc5 221 Gene3D G3DSA:3.40.109.10 5 221 8.7E-41 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS03825 afe62312e50bc525cf19663718251bc5 221 Pfam PF00881 Nitroreductase family 14 201 4.9E-27 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 8.1E-37 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 Gene3D G3DSA:3.50.50.60 2 171 4.8E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 473 3.8E-180 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 SUPERFAMILY SSF51905 1 378 2.31E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 Gene3D G3DSA:3.30.390.30 353 473 8.2E-39 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 2.2E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 3.4E-38 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 3.4E-38 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.4E-38 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 3.4E-38 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 3.4E-38 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 SUPERFAMILY SSF55424 350 472 3.09E-39 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 Gene3D G3DSA:3.40.50.720 172 344 1.4E-31 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PIRSF PIRSF000350 1 470 3.8E-85 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 2.5E-68 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 2.5E-68 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.5E-68 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 2.5E-68 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 2.5E-68 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 2.5E-68 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 2.5E-68 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.5E-68 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 2.5E-68 T 29-03-2018 CXR48_RS11525 f892ebfc392b492dc90a5ae69e0866ec 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CXR48_RS08685 1c76bfb0df97a704fff89899daab6ad6 252 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 172 1.6E-44 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS08685 1c76bfb0df97a704fff89899daab6ad6 252 Pfam PF05036 Sporulation related domain 182 251 2.1E-16 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CXR48_RS08685 1c76bfb0df97a704fff89899daab6ad6 252 Gene3D G3DSA:3.30.70.1070 180 252 8.0E-17 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CXR48_RS08685 1c76bfb0df97a704fff89899daab6ad6 252 SUPERFAMILY SSF110997 181 250 4.18E-16 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CXR48_RS08685 1c76bfb0df97a704fff89899daab6ad6 252 SMART SM00646 64 172 2.0E-45 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS08685 1c76bfb0df97a704fff89899daab6ad6 252 SUPERFAMILY SSF53187 1 178 7.53E-53 T 29-03-2018 CXR48_RS08685 1c76bfb0df97a704fff89899daab6ad6 252 Gene3D G3DSA:3.40.630.40 1 179 1.0E-54 T 29-03-2018 CXR48_RS01680 2644756d167f861e7abc1db79dd2bed2 186 Gene3D G3DSA:3.40.50.300 12 178 8.3E-21 T 29-03-2018 CXR48_RS01680 2644756d167f861e7abc1db79dd2bed2 186 SUPERFAMILY SSF52540 12 176 5.72E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01680 2644756d167f861e7abc1db79dd2bed2 186 Hamap MF_00109 Shikimate kinase [aroK]. 11 177 23.885 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CXR48_RS01680 2644756d167f861e7abc1db79dd2bed2 186 Pfam PF01202 Shikimate kinase 20 177 3.3E-43 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CXR48_RS01680 2644756d167f861e7abc1db79dd2bed2 186 PRINTS PR01100 Shikimate kinase family signature 85 94 7.9E-14 T 29-03-2018 CXR48_RS01680 2644756d167f861e7abc1db79dd2bed2 186 PRINTS PR01100 Shikimate kinase family signature 38 51 7.9E-14 T 29-03-2018 CXR48_RS01680 2644756d167f861e7abc1db79dd2bed2 186 PRINTS PR01100 Shikimate kinase family signature 14 29 7.9E-14 T 29-03-2018 CXR48_RS01680 2644756d167f861e7abc1db79dd2bed2 186 PRINTS PR01100 Shikimate kinase family signature 66 74 7.9E-14 T 29-03-2018 CXR48_RS01680 2644756d167f861e7abc1db79dd2bed2 186 ProSitePatterns PS01128 Shikimate kinase signature. 67 93 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CXR48_RS03850 073561607d87d85c237563f1beb4671c 343 Gene3D G3DSA:3.40.50.2300 174 340 5.4E-50 T 29-03-2018 CXR48_RS03850 073561607d87d85c237563f1beb4671c 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 53 8.6E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS03850 073561607d87d85c237563f1beb4671c 343 Gene3D G3DSA:1.10.260.40 21 64 2.1E-20 T 29-03-2018 CXR48_RS03850 073561607d87d85c237563f1beb4671c 343 Gene3D G3DSA:3.40.50.2300 65 173 5.0E-31 T 29-03-2018 CXR48_RS03850 073561607d87d85c237563f1beb4671c 343 SUPERFAMILY SSF53822 68 338 9.79E-77 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS03850 073561607d87d85c237563f1beb4671c 343 SMART SM00354 8 78 3.8E-27 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS03850 073561607d87d85c237563f1beb4671c 343 Pfam PF13377 Periplasmic binding protein-like domain 176 337 4.2E-39 T 29-03-2018 CXR48_RS03850 073561607d87d85c237563f1beb4671c 343 SUPERFAMILY SSF47413 7 66 2.18E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS03850 073561607d87d85c237563f1beb4671c 343 Gene3D G3DSA:1.10.10.60 3 20 0.13 T 29-03-2018 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 131 143 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 SUPERFAMILY SSF53067 248 488 8.14E-66 T 29-03-2018 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 354 374 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 246 2.0E-70 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 Gene3D G3DSA:3.30.420.40 1 243 5.4E-77 T 29-03-2018 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 440 1.0E-32 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 SUPERFAMILY SSF53067 2 248 6.76E-77 T 29-03-2018 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 TIGRFAM TIGR01312 XylB: xylulokinase 5 483 1.7E-188 T 29-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 PIRSF PIRSF000538 1 495 1.1E-160 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS08745 7709e68982647663703009fcc9e65d2d 499 Gene3D G3DSA:3.30.420.40 244 499 4.7E-65 T 29-03-2018 CXR48_RS17890 b89a47c02da1eb9f84b6186f310a6238 151 Gene3D G3DSA:2.60.120.10 1 151 7.4E-45 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS17890 b89a47c02da1eb9f84b6186f310a6238 151 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 2 147 2.4E-25 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CXR48_RS17890 b89a47c02da1eb9f84b6186f310a6238 151 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 2 147 6.0E-27 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CXR48_RS17890 b89a47c02da1eb9f84b6186f310a6238 151 SUPERFAMILY SSF51182 2 148 1.7E-41 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS14980 081c76d1eeebcc0f7853d20bd78b2589 234 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS14980 081c76d1eeebcc0f7853d20bd78b2589 234 SMART SM00382 26 209 2.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS14980 081c76d1eeebcc0f7853d20bd78b2589 234 Pfam PF00005 ABC transporter 17 161 7.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS14980 081c76d1eeebcc0f7853d20bd78b2589 234 Gene3D G3DSA:3.40.50.300 1 233 3.5E-58 T 29-03-2018 CXR48_RS14980 081c76d1eeebcc0f7853d20bd78b2589 234 SUPERFAMILY SSF52540 2 216 2.33E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03390 d16b8460c020a1f45044f120cd2fb817 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 26.378 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CXR48_RS03390 d16b8460c020a1f45044f120cd2fb817 96 SUPERFAMILY SSF141000 3 94 4.32E-33 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CXR48_RS03390 d16b8460c020a1f45044f120cd2fb817 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 5.2E-37 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CXR48_RS03390 d16b8460c020a1f45044f120cd2fb817 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 5.5E-24 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CXR48_RS16170 07af05e94fa06f8ba9be226df4cbc318 345 SUPERFAMILY SSF53448 4 228 7.97E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16170 07af05e94fa06f8ba9be226df4cbc318 345 Gene3D G3DSA:3.90.550.10 1 273 8.6E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16170 07af05e94fa06f8ba9be226df4cbc318 345 Pfam PF00535 Glycosyl transferase family 2 7 170 1.1E-38 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS13615 fe7ca0e070dff3a25691128bea2fad1c 335 SUPERFAMILY SSF52096 207 268 1.59E-43 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS13615 fe7ca0e070dff3a25691128bea2fad1c 335 SUPERFAMILY SSF52096 51 178 1.59E-43 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS13615 fe7ca0e070dff3a25691128bea2fad1c 335 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 59 280 4.3E-89 T 29-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 CXR48_RS13615 fe7ca0e070dff3a25691128bea2fad1c 335 Pfam PF01343 Peptidase family S49 131 280 1.9E-59 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CXR48_RS13615 fe7ca0e070dff3a25691128bea2fad1c 335 Gene3D G3DSA:3.90.226.10 51 335 4.8E-51 T 29-03-2018 CXR48_RS00425 be391ec21a064e14e55122825223a06b 258 Pfam PF03309 Type III pantothenate kinase 2 206 1.6E-76 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CXR48_RS00425 be391ec21a064e14e55122825223a06b 258 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 250 9.7E-96 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CXR48_RS00425 be391ec21a064e14e55122825223a06b 258 SUPERFAMILY SSF53067 123 253 9.72E-42 T 29-03-2018 CXR48_RS00425 be391ec21a064e14e55122825223a06b 258 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 38.099 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CXR48_RS00425 be391ec21a064e14e55122825223a06b 258 SUPERFAMILY SSF53067 2 122 2.73E-40 T 29-03-2018 CXR48_RS00425 be391ec21a064e14e55122825223a06b 258 Gene3D G3DSA:3.30.420.40 89 257 6.6E-65 T 29-03-2018 CXR48_RS15515 0823227f122721b47c563b37b745f444 422 Gene3D G3DSA:1.20.1250.20 5 208 4.7E-11 T 29-03-2018 CXR48_RS15515 0823227f122721b47c563b37b745f444 422 SUPERFAMILY SSF103473 12 407 2.75E-33 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15515 0823227f122721b47c563b37b745f444 422 Gene3D G3DSA:1.20.1250.20 216 419 1.5E-13 T 29-03-2018 CXR48_RS15515 0823227f122721b47c563b37b745f444 422 Pfam PF07690 Major Facilitator Superfamily 50 368 1.8E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS09300 82ef3def7e4eb12cf7417dbba0ca9b2a 391 SUPERFAMILY SSF103473 5 378 1.44E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS09300 82ef3def7e4eb12cf7417dbba0ca9b2a 391 Pfam PF07690 Major Facilitator Superfamily 10 343 2.8E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS09300 82ef3def7e4eb12cf7417dbba0ca9b2a 391 Gene3D G3DSA:1.20.1250.20 2 190 1.2E-27 T 29-03-2018 CXR48_RS09300 82ef3def7e4eb12cf7417dbba0ca9b2a 391 Gene3D G3DSA:1.20.1250.20 191 391 1.4E-20 T 29-03-2018 CXR48_RS19105 48a9653021a923be2e388ef8591e4376 351 Gene3D G3DSA:3.90.1200.10 98 318 1.4E-11 T 29-03-2018 CXR48_RS19105 48a9653021a923be2e388ef8591e4376 351 SUPERFAMILY SSF56112 30 316 7.66E-26 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS19105 48a9653021a923be2e388ef8591e4376 351 Pfam PF02958 Ecdysteroid kinase 90 282 7.9E-9 T 29-03-2018 IPR004119 Protein of unknown function DUF227 CXR48_RS00885 f54217018d4653d2198fbad03e1791d4 281 SMART SM00382 34 219 7.2E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS00885 f54217018d4653d2198fbad03e1791d4 281 Pfam PF00005 ABC transporter 25 171 1.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS00885 f54217018d4653d2198fbad03e1791d4 281 SUPERFAMILY SSF52540 6 232 3.31E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00885 f54217018d4653d2198fbad03e1791d4 281 Gene3D G3DSA:3.40.50.300 2 242 4.0E-73 T 29-03-2018 CXR48_RS00885 f54217018d4653d2198fbad03e1791d4 281 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS00885 f54217018d4653d2198fbad03e1791d4 281 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 7 275 8.1E-119 T 29-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CXR48_RS02050 f0ac118cacfd77f1c67a362ab9043a85 190 Gene3D G3DSA:1.10.10.10 5 76 1.5E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02050 f0ac118cacfd77f1c67a362ab9043a85 190 SUPERFAMILY SSF46785 6 61 4.32E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02050 f0ac118cacfd77f1c67a362ab9043a85 190 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.6E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS02050 f0ac118cacfd77f1c67a362ab9043a85 190 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.6E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS02050 f0ac118cacfd77f1c67a362ab9043a85 190 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 4.0E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS02050 f0ac118cacfd77f1c67a362ab9043a85 190 SMART SM00420 6 58 7.5E-13 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS02050 f0ac118cacfd77f1c67a362ab9043a85 190 SUPERFAMILY SSF160387 82 188 1.1E-21 T 29-03-2018 CXR48_RS16095 44d0302795c6622680e205f3c0e4fc65 240 SUPERFAMILY SSF100950 48 237 4.18E-39 T 29-03-2018 CXR48_RS16095 44d0302795c6622680e205f3c0e4fc65 240 Pfam PF02589 LUD domain 118 237 2.2E-28 T 29-03-2018 IPR003741 LUD domain CXR48_RS16095 44d0302795c6622680e205f3c0e4fc65 240 Gene3D G3DSA:3.40.50.10420 45 238 6.6E-38 T 29-03-2018 CXR48_RS16095 44d0302795c6622680e205f3c0e4fc65 240 Hamap MF_02104 Lactate utilization protein C [lutC]. 5 237 46.762 T 29-03-2018 IPR022823 Lactate utilization protein C CXR48_RS07775 8fda4fe96a4556399442110000007707 257 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 1.6E-51 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS07775 8fda4fe96a4556399442110000007707 257 Gene3D G3DSA:3.30.950.10 127 254 6.1E-34 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS07775 8fda4fe96a4556399442110000007707 257 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CXR48_RS07775 8fda4fe96a4556399442110000007707 257 Gene3D G3DSA:3.40.1010.10 1 126 2.1E-40 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS07775 8fda4fe96a4556399442110000007707 257 SUPERFAMILY SSF53790 1 244 1.16E-81 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS07775 8fda4fe96a4556399442110000007707 257 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CXR48_RS07775 8fda4fe96a4556399442110000007707 257 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 2.7E-101 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 SUPERFAMILY SSF54106 79 121 1.03E-11 T 29-03-2018 IPR018392 LysM domain CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 Pfam PF06725 3D domain 229 289 9.4E-22 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 Gene3D G3DSA:3.10.350.10 20 75 1.9E-15 T 29-03-2018 CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 SMART SM00257 79 122 2.9E-17 T 29-03-2018 IPR018392 LysM domain CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 SMART SM00257 27 70 8.5E-15 T 29-03-2018 IPR018392 LysM domain CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 Gene3D G3DSA:3.10.350.10 76 122 2.4E-15 T 29-03-2018 CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 SUPERFAMILY SSF50685 231 278 4.88E-9 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 Pfam PF01476 LysM domain 80 121 2.5E-15 T 29-03-2018 IPR018392 LysM domain CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 Pfam PF01476 LysM domain 28 69 5.5E-13 T 29-03-2018 IPR018392 LysM domain CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 Gene3D G3DSA:2.40.40.10 123 289 1.2E-45 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CXR48_RS09480 8dfe4bd00f974525a77feb8788876812 290 SUPERFAMILY SSF54106 27 69 3.27E-10 T 29-03-2018 IPR018392 LysM domain CXR48_RS10860 fc2590af9da64092075fc95b8c67fdb0 224 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 217 7.3E-92 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CXR48_RS10860 fc2590af9da64092075fc95b8c67fdb0 224 Gene3D G3DSA:3.40.50.300 3 223 4.2E-53 T 29-03-2018 CXR48_RS10860 fc2590af9da64092075fc95b8c67fdb0 224 SUPERFAMILY SSF52540 6 220 3.86E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10860 fc2590af9da64092075fc95b8c67fdb0 224 Pfam PF02224 Cytidylate kinase 7 220 1.5E-83 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CXR48_RS10860 fc2590af9da64092075fc95b8c67fdb0 224 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 34.349 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CXR48_RS03310 589ab70285a94ea6dfa920e9bcb5db4e 195 SUPERFAMILY SSF53328 2 186 1.31E-59 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS03310 589ab70285a94ea6dfa920e9bcb5db4e 195 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS03310 589ab70285a94ea6dfa920e9bcb5db4e 195 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 190 2.6E-74 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CXR48_RS03310 589ab70285a94ea6dfa920e9bcb5db4e 195 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 30.113 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CXR48_RS03310 589ab70285a94ea6dfa920e9bcb5db4e 195 Pfam PF00551 Formyl transferase 2 182 3.8E-63 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS03310 589ab70285a94ea6dfa920e9bcb5db4e 195 Gene3D G3DSA:3.40.50.170 1 187 1.2E-62 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 SUPERFAMILY SSF81665 398 493 1.14E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 SUPERFAMILY SSF81665 263 301 1.14E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 Pfam PF00122 E1-E2 ATPase 297 478 6.4E-58 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 SUPERFAMILY SSF55008 73 138 1.83E-20 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 211 801 2.2E-182 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 698 717 6.1E-28 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 634 6.1E-28 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 347 361 6.1E-28 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 645 655 6.1E-28 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 499 513 6.1E-28 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 721 733 6.1E-28 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 Gene3D G3DSA:3.40.1110.10 514 624 1.1E-34 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 SUPERFAMILY SSF55008 3 72 1.96E-19 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 Pfam PF00702 haloacid dehalogenase-like hydrolase 496 712 8.8E-47 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 SUPERFAMILY SSF81653 301 397 1.07E-29 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 Gene3D G3DSA:3.30.70.100 4 72 1.2E-19 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 Gene3D G3DSA:3.30.70.100 73 143 6.0E-22 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 7 70 3.4E-12 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 74 138 3.9E-11 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 Gene3D G3DSA:1.20.1110.10 263 513 3.1E-49 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 ProSitePatterns PS01047 Heavy-metal-associated domain. 79 108 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 Pfam PF00403 Heavy-metal-associated domain 8 69 1.3E-15 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 Pfam PF00403 Heavy-metal-associated domain 77 136 4.4E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00942 Copper-transporting ATPase 1 signature 213 238 2.5E-19 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00942 Copper-transporting ATPase 1 signature 32 55 2.5E-19 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00942 Copper-transporting ATPase 1 signature 193 213 2.5E-19 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 PRINTS PR00942 Copper-transporting ATPase 1 signature 6 31 2.5E-19 T 29-03-2018 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 501 507 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 Gene3D G3DSA:3.40.50.1000 625 763 2.9E-42 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 SUPERFAMILY SSF56784 497 517 3.87E-59 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 SUPERFAMILY SSF56784 556 798 3.87E-59 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 270 782 6.0E-91 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS15735 2f3b0b4e9f8d1fbae1e47935c31631ce 809 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 230 800 1.4E-201 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS05575 ccffdcd4beb03929a0dbb9911ebe28c9 328 Pfam PF00005 ABC transporter 25 183 1.2E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS05575 ccffdcd4beb03929a0dbb9911ebe28c9 328 SMART SM00382 33 234 2.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS05575 ccffdcd4beb03929a0dbb9911ebe28c9 328 SUPERFAMILY SSF52540 4 254 1.33E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05575 ccffdcd4beb03929a0dbb9911ebe28c9 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 1.7E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS05575 ccffdcd4beb03929a0dbb9911ebe28c9 328 Gene3D G3DSA:3.40.50.300 1 328 1.5E-82 T 29-03-2018 CXR48_RS05575 ccffdcd4beb03929a0dbb9911ebe28c9 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 4.2E-21 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS05575 ccffdcd4beb03929a0dbb9911ebe28c9 328 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 Pfam PF00067 Cytochrome P450 85 374 2.1E-26 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00385 P450 superfamily signature 352 363 3.2E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00385 P450 superfamily signature 343 352 3.2E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00385 P450 superfamily signature 276 287 3.2E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00385 P450 superfamily signature 241 258 3.2E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 Gene3D G3DSA:1.10.630.10 1 403 1.4E-81 T 29-03-2018 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 SUPERFAMILY SSF48264 7 396 1.14E-94 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00359 B-class P450 signature 352 363 3.2E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00359 B-class P450 signature 343 352 3.2E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00359 B-class P450 signature 157 172 3.2E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00359 B-class P450 signature 195 217 3.2E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00359 B-class P450 signature 322 337 3.2E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00359 B-class P450 signature 276 287 3.2E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00359 B-class P450 signature 94 105 3.2E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00359 B-class P450 signature 140 156 3.2E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS08585 d5d6053d240e4cfd621dc25410cd8943 403 PRINTS PR00359 B-class P450 signature 294 321 3.2E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS15440 6c41258b76edccadb0e21960e5bd5b29 225 Gene3D G3DSA:1.10.10.10 126 225 2.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15440 6c41258b76edccadb0e21960e5bd5b29 225 SUPERFAMILY SSF46894 131 223 5.67E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS15440 6c41258b76edccadb0e21960e5bd5b29 225 Gene3D G3DSA:3.40.50.2300 2 125 1.1E-28 T 29-03-2018 CXR48_RS15440 6c41258b76edccadb0e21960e5bd5b29 225 SMART SM00862 151 222 3.4E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS15440 6c41258b76edccadb0e21960e5bd5b29 225 Pfam PF00072 Response regulator receiver domain 5 113 4.6E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS15440 6c41258b76edccadb0e21960e5bd5b29 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 222 8.6E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS15440 6c41258b76edccadb0e21960e5bd5b29 225 SMART SM00448 3 113 8.9E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS15440 6c41258b76edccadb0e21960e5bd5b29 225 SUPERFAMILY SSF52172 3 126 8.11E-32 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 Pfam PF02811 PHP domain 5 164 9.3E-35 T 29-03-2018 IPR004013 PHP domain GO:0003824 CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 Gene3D G3DSA:3.20.20.140 1 253 2.1E-36 T 29-03-2018 CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 Pfam PF01336 OB-fold nucleic acid binding domain 962 1023 3.6E-8 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 Gene3D G3DSA:1.10.150.280 761 860 5.9E-6 T 29-03-2018 CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 Gene3D G3DSA:2.40.50.140 937 1031 5.0E-12 T 29-03-2018 CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 SMART SM00481 4 71 3.7E-25 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 990 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 Pfam PF14579 Helix-hairpin-helix motif 776 863 2.9E-24 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 280 702 2.4E-172 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13525 b4fe65a59353a8a166365031c64bceca 1112 SUPERFAMILY SSF89550 3 250 7.06E-17 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 3 450 1.1E-120 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 ProSitePatterns PS00217 Sugar transport proteins signature 2. 112 137 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 Pfam PF00083 Sugar (and other) transporter 15 455 2.6E-120 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 PRINTS PR00171 Sugar transporter signature 107 126 7.6E-24 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 PRINTS PR00171 Sugar transporter signature 356 377 7.6E-24 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 PRINTS PR00171 Sugar transporter signature 22 32 7.6E-24 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 PRINTS PR00171 Sugar transporter signature 379 391 7.6E-24 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 PRINTS PR00171 Sugar transporter signature 267 277 7.6E-24 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 Gene3D G3DSA:1.20.1250.20 1 238 3.5E-35 T 29-03-2018 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 Gene3D G3DSA:1.20.1250.20 239 468 6.7E-37 T 29-03-2018 CXR48_RS02980 e8ea5a25f051f12f559d4ea4243e7f94 472 SUPERFAMILY SSF103473 6 452 2.49E-79 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 2.5E-277 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 SMART SM00437 242 510 7.7E-141 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Gene3D G3DSA:2.70.20.10 327 451 2.2E-41 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 658 689 0.083 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 613 3.9E-16 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 616 655 2.3E-14 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Pfam PF01751 Toprim domain 5 113 1.2E-29 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Gene3D G3DSA:1.10.460.10 135 326 6.0E-51 T 29-03-2018 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Gene3D G3DSA:1.10.460.10 452 563 3.9E-26 T 29-03-2018 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Gene3D G3DSA:3.30.65.10 653 691 9.9E-4 T 29-03-2018 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Gene3D G3DSA:3.30.65.10 615 652 1.7E-9 T 29-03-2018 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Gene3D G3DSA:3.30.65.10 564 614 7.9E-17 T 29-03-2018 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 SMART SM00436 104 192 6.2E-54 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 633 56.257 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 SUPERFAMILY SSF57783 569 613 9.52E-14 T 29-03-2018 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 2.2E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 2.2E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 2.2E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 2.2E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 2.2E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Pfam PF01131 DNA topoisomerase 128 547 4.1E-139 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 SUPERFAMILY SSF56712 4 561 3.92E-203 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 Gene3D G3DSA:3.40.50.140 2 129 1.4E-37 T 29-03-2018 CXR48_RS08035 9a27eaf45cd26674c74292a3f3c2b646 691 SMART SM00493 3 103 5.3E-34 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS08720 59616a5fea02274375eded5fa8d116af 364 Gene3D G3DSA:2.120.10.30 9 364 2.3E-48 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CXR48_RS08720 59616a5fea02274375eded5fa8d116af 364 SUPERFAMILY SSF63829 216 333 3.01E-24 T 29-03-2018 CXR48_RS08720 59616a5fea02274375eded5fa8d116af 364 SUPERFAMILY SSF63829 23 184 3.01E-24 T 29-03-2018 CXR48_RS08720 59616a5fea02274375eded5fa8d116af 364 Pfam PF03022 Major royal jelly protein 80 340 1.8E-32 T 29-03-2018 IPR017996 Major royal jelly protein/protein yellow CXR48_RS19115 a43313134fc15f873877968b24fe0090 444 Pfam PF13439 Glycosyltransferase Family 4 66 244 2.2E-19 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CXR48_RS19115 a43313134fc15f873877968b24fe0090 444 Gene3D G3DSA:3.40.50.2000 248 418 5.0E-41 T 29-03-2018 CXR48_RS19115 a43313134fc15f873877968b24fe0090 444 SUPERFAMILY SSF53756 54 434 2.11E-80 T 29-03-2018 CXR48_RS19115 a43313134fc15f873877968b24fe0090 444 Pfam PF00534 Glycosyl transferases group 1 251 412 2.4E-37 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CXR48_RS19115 a43313134fc15f873877968b24fe0090 444 Gene3D G3DSA:3.40.50.2000 46 247 1.0E-10 T 29-03-2018 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 ProSitePatterns PS00211 ABC transporters family signature. 627 641 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 Gene3D G3DSA:3.40.50.300 478 714 2.4E-57 T 29-03-2018 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 SUPERFAMILY SSF52540 482 703 8.6E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 Pfam PF00005 ABC transporter 506 654 1.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 Pfam PF03412 Peptidase C39 family 8 140 9.3E-26 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 SUPERFAMILY SSF90123 631 640 5.49E-50 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 SUPERFAMILY SSF90123 155 454 5.49E-50 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 Gene3D G3DSA:3.90.70.10 13 154 2.2E-26 T 29-03-2018 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 Pfam PF00664 ABC transporter transmembrane region 174 443 2.4E-30 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 Gene3D G3DSA:1.20.1560.10 155 477 5.4E-44 T 29-03-2018 CXR48_RS06145 7840bbb9213396f2a0b6991b18e94c6d 715 SMART SM00382 515 701 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.8E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.8E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.8E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.8E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 0.0029 T 29-03-2018 CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 PIRSF PIRSF000126 1 237 1.9E-64 T 29-03-2018 CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 8.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 Gene3D G3DSA:3.40.50.720 1 221 4.1E-64 T 29-03-2018 CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 Pfam PF00106 short chain dehydrogenase 7 197 7.6E-66 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09355 a43235c80a845261a7fef5a04fa62879 238 SUPERFAMILY SSF51735 2 220 2.81E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01775 8ea579e6598279c919a7db18b2d7cd5a 211 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 2 207 2.1E-86 T 29-03-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 CXR48_RS01775 8ea579e6598279c919a7db18b2d7cd5a 211 Gene3D G3DSA:3.20.20.70 1 208 2.6E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS01775 8ea579e6598279c919a7db18b2d7cd5a 211 SUPERFAMILY SSF51366 3 209 9.7E-41 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CXR48_RS01775 8ea579e6598279c919a7db18b2d7cd5a 211 SMART SM00934 2 203 4.0E-43 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS01775 8ea579e6598279c919a7db18b2d7cd5a 211 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 202 1.4E-29 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 Gene3D G3DSA:3.40.50.2300 1 121 1.8E-28 T 29-03-2018 CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 SMART SM00421 135 192 7.8E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 2.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 2.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 2.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 SUPERFAMILY SSF52172 1 129 3.27E-29 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 190 1.9E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 SUPERFAMILY SSF46894 121 198 3.3E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 SMART SM00448 2 113 8.5E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 Gene3D G3DSA:1.10.10.10 122 199 6.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18760 2c53fae1bc3f585e47e6d652b3d43c0d 199 Pfam PF00072 Response regulator receiver domain 4 114 7.5E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 Pfam PF07690 Major Facilitator Superfamily 25 361 1.6E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 SUPERFAMILY SSF103473 13 400 8.5E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 13 391 3.1E-102 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 Gene3D G3DSA:1.20.1250.20 9 200 2.8E-30 T 29-03-2018 CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 Gene3D G3DSA:1.20.1250.20 204 400 1.1E-16 T 29-03-2018 CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 PRINTS PR01035 Tetracycline resistance protein signature 109 130 5.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 PRINTS PR01035 Tetracycline resistance protein signature 282 303 5.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 PRINTS PR01035 Tetracycline resistance protein signature 82 106 5.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS17860 0fe3c352187090ca4db6f1d1dded52ca 400 PRINTS PR01035 Tetracycline resistance protein signature 25 41 5.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 Gene3D G3DSA:3.30.70.240 400 560 2.8E-31 T 29-03-2018 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 SUPERFAMILY SSF50447 176 298 1.28E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 SUPERFAMILY SSF54980 302 380 1.01E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 Gene3D G3DSA:2.40.30.10 198 297 2.4E-28 T 29-03-2018 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.9E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 PRINTS PR00315 GTP-binding elongation factor signature 16 29 3.9E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.9E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.9E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.9E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 TIGRFAM TIGR01393 lepA: elongation factor 4 13 606 0.0 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 Hamap MF_00071 Elongation factor 4 [lepA]. 1 608 314.71 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 Pfam PF00009 Elongation factor Tu GTP binding domain 13 191 1.4E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 Gene3D G3DSA:3.40.50.300 9 195 2.6E-36 T 29-03-2018 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 Pfam PF03144 Elongation factor Tu domain 2 215 285 1.0E-12 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 Pfam PF00679 Elongation factor G C-terminus 409 496 2.5E-25 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 SUPERFAMILY SSF52540 10 215 4.67E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 SMART SM00838 411 496 2.7E-4 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 Gene3D G3DSA:3.30.70.870 298 377 7.5E-28 T 29-03-2018 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 184 5.2E-20 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 SUPERFAMILY SSF54980 409 504 1.73E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like CXR48_RS12255 f059b7a6984171575dbd7783719aa2d7 611 Pfam PF06421 GTP-binding protein LepA C-terminus 498 604 2.7E-51 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 Gene3D G3DSA:3.50.50.60 2 420 4.0E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 1.5E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 369 381 1.5E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 1.5E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 97 109 1.5E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 339 345 1.5E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 1.5E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 SUPERFAMILY SSF54373 252 345 3.01E-11 T 29-03-2018 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 28 45 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 SUPERFAMILY SSF51905 160 240 2.21E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 SUPERFAMILY SSF51905 2 116 2.21E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 Pfam PF01266 FAD dependent oxidoreductase 24 353 2.8E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 374 384 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CXR48_RS04635 54ab89f547dd33fc7379a610e897dccf 555 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 406 534 3.5E-25 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CXR48_RS03625 426924dd62c554ef59a4c9c30a280867 355 Gene3D G3DSA:1.25.40.10 280 353 2.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03625 426924dd62c554ef59a4c9c30a280867 355 Gene3D G3DSA:3.90.550.10 2 154 8.6E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS03625 426924dd62c554ef59a4c9c30a280867 355 Gene3D G3DSA:1.25.40.10 175 279 1.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03625 426924dd62c554ef59a4c9c30a280867 355 SUPERFAMILY SSF53448 3 154 1.13E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS03625 426924dd62c554ef59a4c9c30a280867 355 Pfam PF00535 Glycosyl transferase family 2 5 134 1.2E-19 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS03625 426924dd62c554ef59a4c9c30a280867 355 SUPERFAMILY SSF48452 196 350 9.2E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS16155 9f70bf8f8fe31c9a6b0fca570911e48e 505 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 346 482 2.5E-8 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CXR48_RS16155 9f70bf8f8fe31c9a6b0fca570911e48e 505 Pfam PF01943 Polysaccharide biosynthesis protein 9 285 7.8E-12 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CXR48_RS15715 0f84953400dbc56655c0853cf3d0ad97 266 Pfam PF13688 Metallo-peptidase family M12 98 239 2.7E-27 T 29-03-2018 CXR48_RS15715 0f84953400dbc56655c0853cf3d0ad97 266 Gene3D G3DSA:3.40.390.10 66 262 9.1E-20 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CXR48_RS15715 0f84953400dbc56655c0853cf3d0ad97 266 SUPERFAMILY SSF55486 99 258 2.38E-20 T 29-03-2018 CXR48_RS00095 49bbff178e6421ecfa50803dd23aeb29 381 Gene3D G3DSA:3.90.1510.10 42 276 1.2E-93 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CXR48_RS00095 49bbff178e6421ecfa50803dd23aeb29 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 374 9.3E-155 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CXR48_RS00095 49bbff178e6421ecfa50803dd23aeb29 381 SUPERFAMILY SSF110738 1 373 2.75E-136 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CXR48_RS00095 49bbff178e6421ecfa50803dd23aeb29 381 Pfam PF02595 Glycerate kinase family 3 373 1.0E-146 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CXR48_RS00095 49bbff178e6421ecfa50803dd23aeb29 381 PIRSF PIRSF006078 1 378 1.1E-139 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CXR48_RS07010 55c320e3f00b15121a546f49253a7710 151 TIGRFAM TIGR01753 flav_short: flavodoxin 4 143 9.3E-47 T 29-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 CXR48_RS07010 55c320e3f00b15121a546f49253a7710 151 Gene3D G3DSA:3.40.50.360 1 150 4.7E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS07010 55c320e3f00b15121a546f49253a7710 151 PRINTS PR00369 Flavodoxin signature 82 92 1.5E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS07010 55c320e3f00b15121a546f49253a7710 151 PRINTS PR00369 Flavodoxin signature 53 64 1.5E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS07010 55c320e3f00b15121a546f49253a7710 151 PRINTS PR00369 Flavodoxin signature 5 18 1.5E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS07010 55c320e3f00b15121a546f49253a7710 151 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CXR48_RS07010 55c320e3f00b15121a546f49253a7710 151 Pfam PF00258 Flavodoxin 6 136 6.1E-29 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CXR48_RS07010 55c320e3f00b15121a546f49253a7710 151 SUPERFAMILY SSF52218 1 145 2.1E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 SUPERFAMILY SSF53244 294 428 9.71E-38 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 Pfam PF08245 Mur ligase middle domain 106 275 9.3E-25 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 Gene3D G3DSA:3.40.1190.10 90 295 8.2E-41 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 430 1.7E-145 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 432 34.787 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 Gene3D G3DSA:3.90.190.20 296 431 4.5E-25 T 29-03-2018 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 SUPERFAMILY SSF51984 4 88 1.96E-21 T 29-03-2018 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 377 9.4E-19 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 Gene3D G3DSA:3.40.50.720 3 89 1.0E-5 T 29-03-2018 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 SUPERFAMILY SSF53623 87 293 1.7E-58 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS13820 8cc015fd05f6d32c49c9519a155f02ad 432 Pfam PF01225 Mur ligase family, catalytic domain 4 101 7.8E-25 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 SUPERFAMILY SSF50447 204 303 1.47E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 PRINTS PR00315 GTP-binding elongation factor signature 79 89 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 PRINTS PR00315 GTP-binding elongation factor signature 132 141 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 PRINTS PR00315 GTP-binding elongation factor signature 95 106 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 Gene3D G3DSA:2.40.30.10 194 300 1.3E-32 T 29-03-2018 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 Gene3D G3DSA:3.40.50.300 76 193 2.9E-32 T 29-03-2018 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 Gene3D G3DSA:2.40.30.10 302 395 1.2E-30 T 29-03-2018 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 147 4.8E-16 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.16 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 1.9E-60 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 SUPERFAMILY SSF50465 304 396 4.32E-35 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 2.1E-233 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 Gene3D G3DSA:3.40.50.300 1 75 2.0E-10 T 29-03-2018 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 SUPERFAMILY SSF52540 6 220 5.12E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 Pfam PF03144 Elongation factor Tu domain 2 226 295 5.6E-19 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CXR48_RS00720 472bc36293f30b658afc6f2480a37957 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.5E-32 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CXR48_RS06400 3c3b675f40e6833bb807c3bc0e0c581b 316 Gene3D G3DSA:3.10.180.10 1 138 2.9E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS06400 3c3b675f40e6833bb807c3bc0e0c581b 316 Gene3D G3DSA:3.10.180.10 148 316 4.2E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS06400 3c3b675f40e6833bb807c3bc0e0c581b 316 SUPERFAMILY SSF54593 1 292 2.26E-51 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS06400 3c3b675f40e6833bb807c3bc0e0c581b 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 104 1.1E-17 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS06400 3c3b675f40e6833bb807c3bc0e0c581b 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 154 275 1.8E-20 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 436 29.979 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 SMART SM00842 7 194 2.2E-89 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 Gene3D G3DSA:3.30.420.40 195 245 4.1E-7 T 29-03-2018 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 1.0E-131 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 Gene3D G3DSA:3.90.640.10 246 298 1.8E-21 T 29-03-2018 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 Pfam PF14450 Cell division protein FtsA 205 366 5.4E-25 T 29-03-2018 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 Pfam PF14450 Cell division protein FtsA 9 187 1.2E-9 T 29-03-2018 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 Gene3D G3DSA:3.30.420.40 1 185 9.1E-34 T 29-03-2018 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 PIRSF PIRSF003101 1 436 2.4E-148 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 SUPERFAMILY SSF53067 197 368 4.98E-42 T 29-03-2018 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 SUPERFAMILY SSF53067 5 195 3.79E-58 T 29-03-2018 CXR48_RS07605 0f6efa7090a688085c44b973f7408761 437 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 1.1E-22 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 309 4.5E-28 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 5 312 46.799 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 PIRSF PIRSF000102 2 311 4.9E-105 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 SUPERFAMILY SSF51735 4 147 3.29E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 3.2E-172 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 1.6E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 1.6E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 1.6E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 1.6E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 1.6E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 1.6E-41 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 SUPERFAMILY SSF56327 151 309 1.15E-53 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 Gene3D G3DSA:3.90.110.10 150 312 7.8E-50 T 29-03-2018 CXR48_RS13460 b174dcdfdda60d32a4235c7a2d1792ec 312 Gene3D G3DSA:3.40.50.720 7 149 5.1E-40 T 29-03-2018 CXR48_RS18135 54febee0e8bd63f537c2e5edac41f8d0 418 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 11 34 1.7E-7 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CXR48_RS18135 54febee0e8bd63f537c2e5edac41f8d0 418 Pfam PF04261 Dyp-type peroxidase family 68 406 2.2E-114 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CXR48_RS18135 54febee0e8bd63f537c2e5edac41f8d0 418 SUPERFAMILY SSF54909 63 410 6.79E-86 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS18135 54febee0e8bd63f537c2e5edac41f8d0 418 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 5 417 1.3E-175 T 29-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 CXR48_RS18135 54febee0e8bd63f537c2e5edac41f8d0 418 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 68 406 1.4E-100 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 SUPERFAMILY SSF54999 5 102 6.41E-39 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.352 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.3E-20 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.3E-20 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.3E-20 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 3.4E-47 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 Gene3D G3DSA:3.30.70.600 3 102 3.2E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.9E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CXR48_RS00730 e3951e97f9f82491c34b4f58bf503c25 102 SMART SM01403 7 101 5.7E-61 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CXR48_RS18830 b8d7a9385ea2544535fd01c21139e739 448 Pfam PF00324 Amino acid permease 14 443 5.8E-103 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS18830 b8d7a9385ea2544535fd01c21139e739 448 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CXR48_RS18830 b8d7a9385ea2544535fd01c21139e739 448 PIRSF PIRSF006060 1 446 3.4E-68 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS18590 8ff55ac63cb576f2f59c0f84fba77401 421 Gene3D G3DSA:2.30.40.10 2 84 3.7E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS18590 8ff55ac63cb576f2f59c0f84fba77401 421 SUPERFAMILY SSF51556 74 372 3.89E-84 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS18590 8ff55ac63cb576f2f59c0f84fba77401 421 Gene3D G3DSA:3.20.20.140 85 372 2.0E-56 T 29-03-2018 CXR48_RS18590 8ff55ac63cb576f2f59c0f84fba77401 421 SUPERFAMILY SSF51338 3 72 1.63E-23 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS18590 8ff55ac63cb576f2f59c0f84fba77401 421 TIGRFAM TIGR01224 hutI: imidazolonepropionase 36 410 7.0E-162 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18590 8ff55ac63cb576f2f59c0f84fba77401 421 SUPERFAMILY SSF51338 355 415 2.8E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS18590 8ff55ac63cb576f2f59c0f84fba77401 421 Hamap MF_00372 Imidazolonepropionase [hutI]. 6 412 42.972 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18590 8ff55ac63cb576f2f59c0f84fba77401 421 Pfam PF07969 Amidohydrolase family 135 413 3.9E-21 T 29-03-2018 IPR013108 Amidohydrolase 3 CXR48_RS12270 305680d5972f25b49603dfae9cf9cb53 368 TIGRFAM TIGR01441 GPR: GPR endopeptidase 12 368 3.1E-196 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CXR48_RS12270 305680d5972f25b49603dfae9cf9cb53 368 Pfam PF03418 Germination protease 18 367 9.7E-188 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CXR48_RS12270 305680d5972f25b49603dfae9cf9cb53 368 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 10 368 0.0 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CXR48_RS12270 305680d5972f25b49603dfae9cf9cb53 368 Gene3D G3DSA:3.40.50.1450 9 364 4.3E-128 T 29-03-2018 IPR023430 Peptidase HybD-like domain CXR48_RS12270 305680d5972f25b49603dfae9cf9cb53 368 PIRSF PIRSF019549 4 368 1.5E-184 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CXR48_RS12270 305680d5972f25b49603dfae9cf9cb53 368 SUPERFAMILY SSF53163 5 367 1.33E-128 T 29-03-2018 IPR023430 Peptidase HybD-like domain CXR48_RS12270 305680d5972f25b49603dfae9cf9cb53 368 Hamap MF_00626 Germination protease [gpr]. 1 368 161.922 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CXR48_RS09320 b1b878bfbeed27f66d5a655dec34b94c 326 SUPERFAMILY SSF51735 129 298 2.47E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS09320 b1b878bfbeed27f66d5a655dec34b94c 326 Gene3D G3DSA:3.90.180.10 2 151 3.2E-29 T 29-03-2018 CXR48_RS09320 b1b878bfbeed27f66d5a655dec34b94c 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 119 2.6E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS09320 b1b878bfbeed27f66d5a655dec34b94c 326 SUPERFAMILY SSF50129 11 155 3.04E-26 T 29-03-2018 IPR011032 GroES-like CXR48_RS09320 b1b878bfbeed27f66d5a655dec34b94c 326 Gene3D G3DSA:3.90.180.10 265 326 0.0013 T 29-03-2018 CXR48_RS09320 b1b878bfbeed27f66d5a655dec34b94c 326 Pfam PF00107 Zinc-binding dehydrogenase 165 286 3.7E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS09320 b1b878bfbeed27f66d5a655dec34b94c 326 SMART SM00829 10 322 2.0E-11 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS09320 b1b878bfbeed27f66d5a655dec34b94c 326 Gene3D G3DSA:3.40.50.720 152 264 4.6E-22 T 29-03-2018 CXR48_RS05150 d9f467f070cd7a5d50e5890269aa78af 363 Pfam PF00108 Thiolase, N-terminal domain 4 231 6.3E-46 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CXR48_RS05150 d9f467f070cd7a5d50e5890269aa78af 363 PIRSF PIRSF000429 1 363 1.2E-101 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CXR48_RS05150 d9f467f070cd7a5d50e5890269aa78af 363 SUPERFAMILY SSF53901 3 238 1.69E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05150 d9f467f070cd7a5d50e5890269aa78af 363 Gene3D G3DSA:3.40.47.10 1 232 3.9E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05150 d9f467f070cd7a5d50e5890269aa78af 363 Gene3D G3DSA:3.40.47.10 233 359 1.2E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05150 d9f467f070cd7a5d50e5890269aa78af 363 Pfam PF02803 Thiolase, C-terminal domain 243 360 8.8E-31 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CXR48_RS05150 d9f467f070cd7a5d50e5890269aa78af 363 ProSitePatterns PS00737 Thiolases signature 2. 307 323 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CXR48_RS05150 d9f467f070cd7a5d50e5890269aa78af 363 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 5 360 1.2E-103 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CXR48_RS05150 d9f467f070cd7a5d50e5890269aa78af 363 SUPERFAMILY SSF53901 240 361 4.53E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS12890 168d308a52035f4144f91e62665dc764 267 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 263 3.9E-126 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CXR48_RS12890 168d308a52035f4144f91e62665dc764 267 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 219 4.6E-24 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CXR48_RS12890 168d308a52035f4144f91e62665dc764 267 SUPERFAMILY SSF52540 5 262 2.09E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12890 168d308a52035f4144f91e62665dc764 267 Gene3D G3DSA:3.40.50.300 2 242 8.9E-55 T 29-03-2018 CXR48_RS12890 168d308a52035f4144f91e62665dc764 267 PIRSF PIRSF003092 1 267 3.7E-94 T 29-03-2018 IPR025501 ATP binding protein MinD CXR48_RS09365 4fa8d37e7edebec67f9ea148ee029b49 253 ProDom PD315856 ORF119 CPE0798 YOXB 8 246 1.0E-67 T 29-03-2018 IPR020530 Uncharacterised protein family, YoxB CXR48_RS09365 4fa8d37e7edebec67f9ea148ee029b49 253 Gene3D G3DSA:3.40.470.10 6 250 2.5E-35 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CXR48_RS07895 90411fe2acac7b530a55e38d26cb8d78 555 SUPERFAMILY SSF101473 5 202 2.35E-45 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CXR48_RS07895 90411fe2acac7b530a55e38d26cb8d78 555 Pfam PF13684 Dihydroxyacetone kinase family 239 555 4.3E-123 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain CXR48_RS07895 90411fe2acac7b530a55e38d26cb8d78 555 SMART SM01121 239 555 1.4E-186 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain CXR48_RS07895 90411fe2acac7b530a55e38d26cb8d78 555 Pfam PF02734 DAK2 domain 36 200 9.9E-42 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CXR48_RS07895 90411fe2acac7b530a55e38d26cb8d78 555 SMART SM01120 36 201 3.8E-72 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CXR48_RS07895 90411fe2acac7b530a55e38d26cb8d78 555 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 555 1.1E-213 T 29-03-2018 IPR019986 DAK2 domain-containing protein YloV CXR48_RS08935 dea4fd42e6db7b162055552f51f74650 48 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 48 7.0E-19 T 29-03-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 CXR48_RS08935 dea4fd42e6db7b162055552f51f74650 48 Hamap MF_00665 Small, acid-soluble spore protein O [sspO]. 1 48 20.261 T 29-03-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 CXR48_RS08935 dea4fd42e6db7b162055552f51f74650 48 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 48 3.2E-27 T 29-03-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 CXR48_RS08935 dea4fd42e6db7b162055552f51f74650 48 Pfam PF08175 Small acid-soluble spore protein O family 2 48 1.5E-25 T 29-03-2018 CXR48_RS07075 712af436faa3b699a1873d76d392c68a 77 SUPERFAMILY SSF54285 1 77 3.74E-15 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CXR48_RS07075 712af436faa3b699a1873d76d392c68a 77 Gene3D G3DSA:3.10.20.30 2 77 2.6E-17 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS07075 712af436faa3b699a1873d76d392c68a 77 Pfam PF02597 ThiS family 4 77 2.7E-14 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CXR48_RS07075 712af436faa3b699a1873d76d392c68a 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 2.0E-22 T 29-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CXR48_RS02115 cf466df34964f197570e786857640d73 249 SUPERFAMILY SSF55781 61 249 2.9E-47 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS02115 cf466df34964f197570e786857640d73 249 SMART SM00346 5 93 4.2E-26 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CXR48_RS02115 cf466df34964f197570e786857640d73 249 Gene3D G3DSA:3.30.450.40 75 249 5.7E-45 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS02115 cf466df34964f197570e786857640d73 249 Pfam PF09339 IclR helix-turn-helix domain 8 55 2.6E-9 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CXR48_RS02115 cf466df34964f197570e786857640d73 249 Pfam PF01614 Bacterial transcriptional regulator 120 245 3.1E-35 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CXR48_RS02115 cf466df34964f197570e786857640d73 249 SUPERFAMILY SSF46785 7 76 6.69E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02115 cf466df34964f197570e786857640d73 249 Gene3D G3DSA:1.10.10.10 3 64 1.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03360 966835accce6ed41e74ee8818882404e 739 Gene3D G3DSA:3.40.50.300 204 680 8.0E-92 T 29-03-2018 CXR48_RS03360 966835accce6ed41e74ee8818882404e 739 Gene3D G3DSA:1.10.10.160 130 190 1.6E-23 T 29-03-2018 CXR48_RS03360 966835accce6ed41e74ee8818882404e 739 Gene3D G3DSA:3.40.50.300 2 129 3.2E-30 T 29-03-2018 CXR48_RS03360 966835accce6ed41e74ee8818882404e 739 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 8 737 0.0 T 29-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CXR48_RS03360 966835accce6ed41e74ee8818882404e 739 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 275 2.9E-83 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CXR48_RS03360 966835accce6ed41e74ee8818882404e 739 SUPERFAMILY SSF52540 1 648 4.38E-185 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03360 966835accce6ed41e74ee8818882404e 739 Pfam PF13361 UvrD-like helicase C-terminal domain 280 621 4.2E-73 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CXR48_RS14635 ae150aea70251335fa661820e6d8c263 387 Pfam PF00155 Aminotransferase class I and II 42 381 3.0E-42 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS14635 ae150aea70251335fa661820e6d8c263 387 Gene3D G3DSA:3.90.1150.10 1 71 2.5E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS14635 ae150aea70251335fa661820e6d8c263 387 Gene3D G3DSA:3.90.1150.10 271 387 4.7E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS14635 ae150aea70251335fa661820e6d8c263 387 SUPERFAMILY SSF53383 2 386 7.75E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS14635 ae150aea70251335fa661820e6d8c263 387 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 386 1.1E-148 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CXR48_RS14635 ae150aea70251335fa661820e6d8c263 387 Gene3D G3DSA:3.40.640.10 72 270 2.0E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS09950 0d7e833277f0d6aa95accd0b41d511d6 152 Gene3D G3DSA:3.40.1580.10 2 152 6.6E-34 T 29-03-2018 CXR48_RS09950 0d7e833277f0d6aa95accd0b41d511d6 152 SMART SM00860 22 135 3.2E-12 T 29-03-2018 IPR018958 Knr4/Smi1-like domain CXR48_RS09950 0d7e833277f0d6aa95accd0b41d511d6 152 SUPERFAMILY SSF160631 1 150 1.23E-39 T 29-03-2018 CXR48_RS09950 0d7e833277f0d6aa95accd0b41d511d6 152 Pfam PF14567 SMI1-KNR4 cell-wall 7 137 3.4E-33 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1567 1582 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SUPERFAMILY SSF53901 879 1232 1.81E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 882 1114 1.1E-79 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SMART SM00829 538 851 1.8E-111 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:3.40.50.720 678 789 2.2E-20 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:3.40.47.10 1129 1291 6.2E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SUPERFAMILY SSF53335 133 329 3.96E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SUPERFAMILY SSF51735 642 798 3.7E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SUPERFAMILY SSF47336 1536 1620 2.09E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF00975 Thioesterase domain 1755 2031 5.3E-35 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SMART SM00825 Beta-ketoacyl synthase 884 1293 2.4E-187 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SUPERFAMILY SSF47336 1643 1720 6.28E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:3.40.47.10 875 1126 2.7E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 556 620 6.5E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SUPERFAMILY SSF50129 529 678 2.2E-30 T 29-03-2018 IPR011032 GroES-like CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SMART SM01294 401 467 7.9E-7 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SMART SM01294 1542 1608 8.2E-41 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SMART SM01294 1646 1712 3.9E-39 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:3.90.180.10 790 855 4.0E-4 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF08242 Methyltransferase domain 169 272 1.3E-12 T 29-03-2018 IPR013217 Methyltransferase type 12 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 ProSitePatterns PS00012 Phosphopantetheine attachment site. 426 441 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF00107 Zinc-binding dehydrogenase 680 784 1.3E-23 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1671 1686 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SMART SM00823 Phosphopantetheine attachment site 1645 1716 2.2E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SMART SM00823 Phosphopantetheine attachment site 400 471 4.9E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SMART SM00823 Phosphopantetheine attachment site 1541 1612 4.9E-18 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SUPERFAMILY SSF47336 866 893 9.16E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SUPERFAMILY SSF47336 398 472 9.16E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:3.90.180.10 512 677 3.7E-40 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1027 1043 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1243 1352 2.7E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:3.40.50.1820 1740 2037 4.3E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1122 1239 2.4E-39 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF00550 Phosphopantetheine attachment site 1647 1712 5.6E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF00550 Phosphopantetheine attachment site 1543 1608 8.3E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Pfam PF00550 Phosphopantetheine attachment site 402 467 3.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:3.40.50.150 70 339 5.9E-16 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:1.10.1200.10 1642 1739 9.1E-16 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:1.10.1200.10 1533 1640 1.1E-18 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 Gene3D G3DSA:1.10.1200.10 392 511 2.9E-13 T 29-03-2018 CXR48_RS11330 fe520d7915be7f2738590e37802eefaf 2071 SUPERFAMILY SSF53474 1735 2033 8.45E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS00865 eef8e12edafd89c201e1b546fa7d812a 121 Gene3D G3DSA:4.10.910.10 86 121 5.0E-26 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00865 eef8e12edafd89c201e1b546fa7d812a 121 Gene3D G3DSA:1.10.8.50 1 66 3.1E-26 T 29-03-2018 CXR48_RS00865 eef8e12edafd89c201e1b546fa7d812a 121 Gene3D G3DSA:4.10.910.10 67 85 2.3E-18 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00865 eef8e12edafd89c201e1b546fa7d812a 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 8.4E-34 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00865 eef8e12edafd89c201e1b546fa7d812a 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00865 eef8e12edafd89c201e1b546fa7d812a 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.5E-52 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00865 eef8e12edafd89c201e1b546fa7d812a 121 SUPERFAMILY SSF46946 2 114 3.93E-45 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CXR48_RS00865 eef8e12edafd89c201e1b546fa7d812a 121 PIRSF PIRSF002134 1 121 6.9E-42 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00865 eef8e12edafd89c201e1b546fa7d812a 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 28.708 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS01275 1bbfaaeeace2258afc419545c5b16398 481 SUPERFAMILY SSF56645 3 273 1.47E-68 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CXR48_RS01275 1bbfaaeeace2258afc419545c5b16398 481 PIRSF PIRSF000331 1 481 3.9E-144 T 29-03-2018 IPR004925 HpaB/PvcC/4-BUDH CXR48_RS01275 1bbfaaeeace2258afc419545c5b16398 481 Gene3D G3DSA:1.20.140.10 283 478 4.3E-71 T 29-03-2018 CXR48_RS01275 1bbfaaeeace2258afc419545c5b16398 481 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 6 271 4.2E-84 T 29-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal CXR48_RS01275 1bbfaaeeace2258afc419545c5b16398 481 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 283 477 2.2E-65 T 29-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal CXR48_RS01275 1bbfaaeeace2258afc419545c5b16398 481 TIGRFAM TIGR02309 HpaB-1: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 5 478 6.2E-156 T 29-03-2018 IPR012687 4-HPA 3-monooxygenase large component, Deinococcus-type GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 CXR48_RS01275 1bbfaaeeace2258afc419545c5b16398 481 SUPERFAMILY SSF47203 263 479 2.51E-60 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CXR48_RS01275 1bbfaaeeace2258afc419545c5b16398 481 Gene3D G3DSA:1.10.3140.10 3 146 2.5E-41 T 29-03-2018 CXR48_RS01275 1bbfaaeeace2258afc419545c5b16398 481 Gene3D G3DSA:2.40.110.10 147 274 6.5E-12 T 29-03-2018 CXR48_RS10030 00ba835934f166075c16bf69accf43a2 207 Gene3D G3DSA:3.40.1130.10 22 206 3.9E-12 T 29-03-2018 CXR48_RS10030 00ba835934f166075c16bf69accf43a2 207 SUPERFAMILY SSF69593 17 176 2.09E-12 T 29-03-2018 CXR48_RS18840 294968c72eb11f7b18df62c71810ac7f 154 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 57 3.8E-5 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CXR48_RS18840 294968c72eb11f7b18df62c71810ac7f 154 SUPERFAMILY SSF54292 5 87 1.7E-21 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CXR48_RS18840 294968c72eb11f7b18df62c71810ac7f 154 Gene3D G3DSA:3.10.20.30 1 76 9.6E-24 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS18840 294968c72eb11f7b18df62c71810ac7f 154 SUPERFAMILY SSF47741 75 148 3.66E-29 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CXR48_RS18840 294968c72eb11f7b18df62c71810ac7f 154 Pfam PF01799 [2Fe-2S] binding domain 75 144 5.8E-27 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CXR48_RS18840 294968c72eb11f7b18df62c71810ac7f 154 Gene3D G3DSA:1.10.150.120 77 154 5.3E-28 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CXR48_RS18840 294968c72eb11f7b18df62c71810ac7f 154 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 Pfam PF03466 LysR substrate binding domain 88 287 2.6E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 Gene3D G3DSA:1.10.10.10 1 84 1.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 Gene3D G3DSA:3.40.190.10 92 175 7.4E-20 T 29-03-2018 CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 Gene3D G3DSA:3.40.190.10 176 263 1.2E-14 T 29-03-2018 CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 SUPERFAMILY SSF46785 1 111 1.61E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 SUPERFAMILY SSF53850 91 290 5.27E-34 T 29-03-2018 CXR48_RS16065 0b6622869d9616706e3065030d7191da 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.7E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16845 552cbc0b546b4958e5feee1f35f5b708 881 Gene3D G3DSA:3.30.70.1070 41 108 0.16 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CXR48_RS16845 552cbc0b546b4958e5feee1f35f5b708 881 Gene3D G3DSA:2.40.50.110 603 691 2.1E-9 T 29-03-2018 CXR48_RS16845 552cbc0b546b4958e5feee1f35f5b708 881 Gene3D G3DSA:1.10.530.10 725 867 5.5E-27 T 29-03-2018 CXR48_RS16845 552cbc0b546b4958e5feee1f35f5b708 881 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 735 862 4.2E-11 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CXR48_RS16845 552cbc0b546b4958e5feee1f35f5b708 881 SMART SM00047 722 874 3.0E-57 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CXR48_RS16845 552cbc0b546b4958e5feee1f35f5b708 881 SMART SM00287 629 699 8.4E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS16845 552cbc0b546b4958e5feee1f35f5b708 881 Pfam PF08239 Bacterial SH3 domain 638 679 2.6E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS16845 552cbc0b546b4958e5feee1f35f5b708 881 Pfam PF05036 Sporulation related domain 245 306 1.2E-4 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CXR48_RS02165 01990fa725b359800e0210486ae682d5 207 SUPERFAMILY SSF55729 8 176 1.01E-40 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS02165 01990fa725b359800e0210486ae682d5 207 Pfam PF13302 Acetyltransferase (GNAT) domain 9 151 1.9E-25 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS02165 01990fa725b359800e0210486ae682d5 207 Gene3D G3DSA:3.40.630.30 3 183 2.1E-33 T 29-03-2018 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 5.3E-135 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 SUPERFAMILY SSF55347 152 314 1.16E-70 T 29-03-2018 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 SUPERFAMILY SSF51735 1 178 4.7E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 SMART SM00846 3 152 7.5E-89 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 6.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 6.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 6.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 6.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 6.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 PIRSF PIRSF000149 1 335 5.3E-140 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 Gene3D G3DSA:3.30.360.10 162 315 2.9E-65 T 29-03-2018 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.5E-67 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 9.4E-39 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS13410 16a966e92b10121d66ee0f50ab9f0d7d 340 Gene3D G3DSA:3.40.50.720 1 161 4.5E-77 T 29-03-2018 CXR48_RS08800 22f24db15c939fc788edc57c4c5af672 180 SUPERFAMILY SSF55729 2 150 2.76E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS08800 22f24db15c939fc788edc57c4c5af672 180 Gene3D G3DSA:3.40.630.30 1 178 4.2E-21 T 29-03-2018 CXR48_RS08800 22f24db15c939fc788edc57c4c5af672 180 Pfam PF13302 Acetyltransferase (GNAT) domain 8 140 1.1E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS10250 309e80bfb23a803a4437f9e0c45512f9 567 PRINTS PR01002 Flagellar protein FlgJ signature 110 129 5.5E-8 T 29-03-2018 CXR48_RS10250 309e80bfb23a803a4437f9e0c45512f9 567 PRINTS PR01002 Flagellar protein FlgJ signature 25 43 5.5E-8 T 29-03-2018 CXR48_RS10250 309e80bfb23a803a4437f9e0c45512f9 567 PRINTS PR01002 Flagellar protein FlgJ signature 130 148 5.5E-8 T 29-03-2018 CXR48_RS10250 309e80bfb23a803a4437f9e0c45512f9 567 Gene3D G3DSA:1.10.530.10 1 152 4.7E-38 T 29-03-2018 CXR48_RS10250 309e80bfb23a803a4437f9e0c45512f9 567 Pfam PF06605 Prophage endopeptidase tail 225 546 3.3E-57 T 29-03-2018 IPR010572 Prophage tail endopeptidase CXR48_RS10250 309e80bfb23a803a4437f9e0c45512f9 567 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 13 148 1.1E-22 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CXR48_RS10250 309e80bfb23a803a4437f9e0c45512f9 567 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 257 485 7.4E-10 T 29-03-2018 IPR007119 Phage minor structural protein, N-terminal domain CXR48_RS10250 309e80bfb23a803a4437f9e0c45512f9 567 SMART SM00047 2 153 3.9E-46 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CXR48_RS17275 6bfada2df69c88459c8e77cb4eab7d45 289 SUPERFAMILY SSF51261 112 220 3.14E-27 T 29-03-2018 IPR011055 Duplicated hybrid motif CXR48_RS17275 6bfada2df69c88459c8e77cb4eab7d45 289 Gene3D G3DSA:2.70.70.10 73 267 8.7E-33 T 29-03-2018 CXR48_RS17275 6bfada2df69c88459c8e77cb4eab7d45 289 Pfam PF01551 Peptidase family M23 119 216 7.9E-25 T 29-03-2018 IPR016047 Peptidase M23 CXR48_RS05235 374f782432033c11180fb66753e78b53 171 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 23 39 1.3E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS05235 374f782432033c11180fb66753e78b53 171 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 132 151 1.3E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS05235 374f782432033c11180fb66753e78b53 171 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 73 85 1.3E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS05235 374f782432033c11180fb66753e78b53 171 ProSitePatterns PS00760 Signal peptidases I lysine active site. 75 87 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CXR48_RS05235 374f782432033c11180fb66753e78b53 171 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 9 165 6.0E-44 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS05235 374f782432033c11180fb66753e78b53 171 Pfam PF00717 Peptidase S24-like 29 97 5.8E-17 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS05235 374f782432033c11180fb66753e78b53 171 Gene3D G3DSA:2.10.109.10 20 166 2.9E-35 T 29-03-2018 CXR48_RS05235 374f782432033c11180fb66753e78b53 171 ProSitePatterns PS00501 Signal peptidases I serine active site. 32 39 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CXR48_RS05235 374f782432033c11180fb66753e78b53 171 SUPERFAMILY SSF51306 25 166 1.57E-41 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS05235 374f782432033c11180fb66753e78b53 171 ProSitePatterns PS00761 Signal peptidases I signature 3. 137 150 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 Gene3D G3DSA:3.30.70.250 3 82 9.5E-39 T 29-03-2018 CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 45.499 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 1.0E-118 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 2.0E-10 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 118 3.5E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 SUPERFAMILY SSF51161 39 223 3.8E-50 T 29-03-2018 IPR011004 Trimeric LpxA-like CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 198 6.8E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 Gene3D G3DSA:2.160.10.10 83 235 7.6E-44 T 29-03-2018 CXR48_RS07015 626fef6d68837964897b8bb0fb959fd8 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 9.5E-37 T 29-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 Pfam PF01497 Periplasmic binding protein 292 501 1.1E-17 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 SUPERFAMILY SSF46689 165 214 3.05E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 SMART SM00342 180 263 7.5E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 Gene3D G3DSA:1.10.10.60 231 251 2.3E-9 T 29-03-2018 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 217 259 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 Gene3D G3DSA:3.40.50.1980 378 530 1.9E-22 T 29-03-2018 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 232 247 2.1E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 263 2.1E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 Gene3D G3DSA:3.40.50.1980 271 377 1.3E-7 T 29-03-2018 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 SUPERFAMILY SSF46689 216 267 1.88E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 SUPERFAMILY SSF53807 268 525 6.28E-32 T 29-03-2018 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 Pfam PF12833 Helix-turn-helix domain 186 264 1.7E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 Gene3D G3DSA:3.90.1240.10 82 230 3.2E-19 T 29-03-2018 CXR48_RS01020 f3c9d4fff7f77d7a31126775118fea15 531 Gene3D G3DSA:3.90.1240.10 252 270 6.3E-6 T 29-03-2018 CXR48_RS01700 5f75127a32bfd0438fd99f8e41103da5 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 515 8.5E-291 T 29-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CXR48_RS01700 5f75127a32bfd0438fd99f8e41103da5 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS01700 5f75127a32bfd0438fd99f8e41103da5 515 Gene3D G3DSA:3.40.309.10 302 490 2.1E-63 T 29-03-2018 CXR48_RS01700 5f75127a32bfd0438fd99f8e41103da5 515 Gene3D G3DSA:3.40.605.10 23 301 2.2E-87 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS01700 5f75127a32bfd0438fd99f8e41103da5 515 Pfam PF00171 Aldehyde dehydrogenase family 50 511 3.9E-155 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS01700 5f75127a32bfd0438fd99f8e41103da5 515 SUPERFAMILY SSF53720 4 511 2.36E-156 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS01700 5f75127a32bfd0438fd99f8e41103da5 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS01700 5f75127a32bfd0438fd99f8e41103da5 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 67.877 T 29-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 Gene3D G3DSA:3.30.1330.10 49 183 9.6E-48 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 Gene3D G3DSA:3.30.1330.10 419 567 1.6E-54 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 SUPERFAMILY SSF56042 572 738 1.09E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 445 562 1.1E-25 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 89 194 2.3E-25 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 742 329.145 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 575 706 9.9E-13 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 359 1.1E-31 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 Gene3D G3DSA:3.90.650.10 184 377 1.8E-34 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 SUPERFAMILY SSF56042 204 430 4.49E-56 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 PIRSF PIRSF001587 8 741 0.0 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 SUPERFAMILY SSF55326 19 201 5.68E-52 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 Gene3D G3DSA:3.90.650.10 569 740 2.0E-31 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 SUPERFAMILY SSF55326 400 569 9.81E-57 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03295 5342bf8f1304c703638447de876fd414 742 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 24 737 0.0 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Gene3D G3DSA:3.10.600.10 992 1062 1.4E-21 T 29-03-2018 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 SUPERFAMILY SSF51246 341 460 1.41E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 SUPERFAMILY SSF51569 526 837 3.48E-81 T 29-03-2018 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 SUPERFAMILY SSF89000 834 1010 3.22E-58 T 29-03-2018 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Gene3D G3DSA:3.30.470.20 215 455 2.3E-92 T 29-03-2018 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Pfam PF00289 Biotin carboxylase, N-terminal domain 6 114 2.0E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 PIRSF PIRSF001594 1 1147 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Gene3D G3DSA:1.10.10.60 945 991 7.8E-17 T 29-03-2018 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 SUPERFAMILY SSF52440 5 117 3.24E-45 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 326 1.9E-78 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Pfam PF02436 Conserved carboxylase domain 829 1029 1.9E-77 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Gene3D G3DSA:3.20.20.70 533 826 1.8E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 SMART SM00878 346 453 9.0E-50 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Gene3D G3DSA:2.40.50.100 1075 1147 2.7E-18 T 29-03-2018 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 SUPERFAMILY SSF56059 88 329 6.36E-71 T 29-03-2018 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Gene3D G3DSA:3.10.600.10 465 532 9.1E-21 T 29-03-2018 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 8 1146 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Gene3D G3DSA:3.30.1490.20 129 214 8.5E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Pfam PF00682 HMGL-like 534 806 2.5E-25 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Pfam PF00364 Biotin-requiring enzyme 1079 1145 4.5E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 SUPERFAMILY SSF51230 1071 1146 7.85E-21 T 29-03-2018 IPR011053 Single hybrid motif CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Pfam PF02785 Biotin carboxylase C-terminal domain 346 453 1.2E-31 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS07405 12e99be7dcfbbca89130065c2e4da9b0 1148 Gene3D G3DSA:3.40.50.20 5 128 1.9E-52 T 29-03-2018 CXR48_RS12090 ccab8b675acd1f7ab7270ea1c001c809 234 SUPERFAMILY SSF53335 7 101 1.01E-6 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS12090 ccab8b675acd1f7ab7270ea1c001c809 234 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 20 229 2.8E-73 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CXR48_RS12090 ccab8b675acd1f7ab7270ea1c001c809 234 Gene3D G3DSA:3.40.50.150 1 163 1.5E-13 T 29-03-2018 CXR48_RS12090 ccab8b675acd1f7ab7270ea1c001c809 234 PIRSF PIRSF018637 1 234 9.8E-88 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CXR48_RS10385 a2ee8c5db5b48e3620f755d8aabfa2e9 142 SUPERFAMILY SSF103084 3 140 1.83E-24 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CXR48_RS10385 a2ee8c5db5b48e3620f755d8aabfa2e9 142 Gene3D G3DSA:3.30.1330.70 1 142 1.4E-32 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CXR48_RS10385 a2ee8c5db5b48e3620f755d8aabfa2e9 142 Pfam PF05866 Endodeoxyribonuclease RusA 10 137 7.9E-33 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:3.90.1800.10 1072 1116 8.1E-12 T 29-03-2018 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 SUPERFAMILY SSF64484 367 1157 0.0 T 29-03-2018 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 SUPERFAMILY SSF64484 13 288 0.0 T 29-03-2018 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04560 RNA polymerase Rpb2, domain 7 1071 1145 4.7E-27 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:3.90.1100.10 20 240 4.3E-57 T 29-03-2018 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:3.90.1100.10 605 671 8.7E-13 T 29-03-2018 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:3.90.1100.10 337 604 2.4E-82 T 29-03-2018 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF10385 RNA polymerase beta subunit external 1 domain 547 614 6.1E-25 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 ProSitePatterns PS01166 RNA polymerases beta chain signature. 922 934 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04561 RNA polymerase Rpb2, domain 2 371 410 1.4E-6 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 1.7E-27 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:2.40.270.10 752 850 7.3E-11 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:2.40.50.100 673 751 2.0E-24 T 29-03-2018 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04563 RNA polymerase beta subunit 28 454 3.1E-30 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1147 12.582 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:2.40.270.10 851 1055 5.4E-76 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 896 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF00562 RNA polymerase Rpb2, domain 6 676 1069 2.2E-164 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00690 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04565 RNA polymerase Rpb2, domain 3 469 537 3.5E-30 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS03235 b4f97c5111a0aa7f6e7a99ff84af93f7 480 Gene3D G3DSA:2.60.40.1630 74 215 2.1E-23 T 29-03-2018 CXR48_RS03235 b4f97c5111a0aa7f6e7a99ff84af93f7 480 Pfam PF13786 Domain of unknown function (DUF4179) 44 133 2.0E-13 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 CXR48_RS05955 094fcb5da1a04f42dae5e25d28a0be84 104 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 10 101 9.0E-32 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS05955 094fcb5da1a04f42dae5e25d28a0be84 104 SUPERFAMILY SSF46973 1 101 2.09E-32 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS05955 094fcb5da1a04f42dae5e25d28a0be84 104 PIRSF PIRSF000699 1 104 3.3E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS05955 094fcb5da1a04f42dae5e25d28a0be84 104 Gene3D G3DSA:1.20.58.80 4 102 1.2E-34 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS03920 8f6f53d8c2d3919571952cad33158e8e 263 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 30 253 1.7E-112 T 29-03-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA CXR48_RS03920 8f6f53d8c2d3919571952cad33158e8e 263 SUPERFAMILY SSF88713 43 253 2.97E-64 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CXR48_RS03920 8f6f53d8c2d3919571952cad33158e8e 263 Pfam PF01522 Polysaccharide deacetylase 61 184 1.7E-34 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CXR48_RS03920 8f6f53d8c2d3919571952cad33158e8e 263 Gene3D G3DSA:3.20.20.370 24 261 7.1E-60 T 29-03-2018 CXR48_RS10435 a803fbef19f779267baf806b806738ee 242 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 14 99 1.2E-28 T 29-03-2018 IPR014054 Bacteriophage regulatory protein, Rha family CXR48_RS10435 a803fbef19f779267baf806b806738ee 242 TIGRFAM TIGR02681 phage_pRha: phage regulatory protein, Rha family 4 103 3.0E-31 T 29-03-2018 IPR014054 Bacteriophage regulatory protein, Rha family CXR48_RS10435 a803fbef19f779267baf806b806738ee 242 Pfam PF03374 Phage antirepressor protein KilAC domain 132 238 7.3E-23 T 29-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 CXR48_RS10475 218ac9ec9da3fbdf030dc0fe769db991 639 Gene3D G3DSA:3.40.50.300 36 457 2.2E-19 T 29-03-2018 CXR48_RS10475 218ac9ec9da3fbdf030dc0fe769db991 639 SMART SM00491 497 626 1.9E-8 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CXR48_RS10475 218ac9ec9da3fbdf030dc0fe769db991 639 SUPERFAMILY SSF52540 418 613 1.86E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10475 218ac9ec9da3fbdf030dc0fe769db991 639 SUPERFAMILY SSF52540 52 107 1.86E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10475 218ac9ec9da3fbdf030dc0fe769db991 639 SUPERFAMILY SSF52540 197 279 1.86E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10475 218ac9ec9da3fbdf030dc0fe769db991 639 Gene3D G3DSA:3.40.50.300 460 633 2.2E-11 T 29-03-2018 CXR48_RS10475 218ac9ec9da3fbdf030dc0fe769db991 639 Pfam PF13307 Helicase C-terminal domain 482 615 2.6E-25 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CXR48_RS10870 564f55e190712fb39a30071d5d1ec3a9 449 Pfam PF03413 Peptidase propeptide and YPEB domain 377 436 0.0029 T 29-03-2018 IPR025711 PepSY domain CXR48_RS10870 564f55e190712fb39a30071d5d1ec3a9 449 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 439 4.5E-164 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 CXR48_RS10870 564f55e190712fb39a30071d5d1ec3a9 449 Pfam PF14620 YpeB sporulation 13 373 1.0E-132 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 CXR48_RS06510 900921f078e47a4cfc16a5b7b80f4faa 415 Gene3D G3DSA:3.40.605.10 1 234 2.0E-38 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS06510 900921f078e47a4cfc16a5b7b80f4faa 415 Pfam PF00171 Aldehyde dehydrogenase family 308 377 1.2E-5 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS06510 900921f078e47a4cfc16a5b7b80f4faa 415 Pfam PF00171 Aldehyde dehydrogenase family 9 281 2.8E-13 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS06510 900921f078e47a4cfc16a5b7b80f4faa 415 SUPERFAMILY SSF53720 2 414 9.95E-109 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS06510 900921f078e47a4cfc16a5b7b80f4faa 415 Gene3D G3DSA:3.40.605.10 235 415 7.0E-38 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS06510 900921f078e47a4cfc16a5b7b80f4faa 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 404 3.0E-177 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS06510 900921f078e47a4cfc16a5b7b80f4faa 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 321 342 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS06510 900921f078e47a4cfc16a5b7b80f4faa 415 PIRSF PIRSF000151 1 415 1.2E-171 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CXR48_RS06510 900921f078e47a4cfc16a5b7b80f4faa 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 414 40.472 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS01830 afdc4c28dd8c6bbaae0ab1ee394eb32b 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 261 9.8E-56 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS01830 afdc4c28dd8c6bbaae0ab1ee394eb32b 265 SMART SM00062 44 262 6.8E-80 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS01830 afdc4c28dd8c6bbaae0ab1ee394eb32b 265 Gene3D G3DSA:3.40.190.10 1 155 6.7E-33 T 29-03-2018 CXR48_RS01830 afdc4c28dd8c6bbaae0ab1ee394eb32b 265 SUPERFAMILY SSF53850 1 262 1.2E-62 T 29-03-2018 CXR48_RS01830 afdc4c28dd8c6bbaae0ab1ee394eb32b 265 Gene3D G3DSA:3.40.190.10 156 258 3.6E-23 T 29-03-2018 CXR48_RS01830 afdc4c28dd8c6bbaae0ab1ee394eb32b 265 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 68 81 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CXR48_RS07210 fd23348112841afee6fdcf6c4b90d069 212 SUPERFAMILY SSF140423 23 210 1.02E-54 T 29-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CXR48_RS07210 fd23348112841afee6fdcf6c4b90d069 212 Pfam PF10368 Putative cell-wall binding lipoprotein 17 210 2.1E-62 T 29-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CXR48_RS07210 fd23348112841afee6fdcf6c4b90d069 212 Gene3D G3DSA:1.20.120.570 14 209 7.5E-43 T 29-03-2018 CXR48_RS16570 dbfaa9f24463c586d0fce8eb51e43912 359 Gene3D G3DSA:3.40.390.10 143 331 5.3E-4 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CXR48_RS16570 dbfaa9f24463c586d0fce8eb51e43912 359 Pfam PF12725 Protein of unknown function (DUF3810) 25 346 3.2E-97 T 29-03-2018 IPR024294 Protein of unknown function DUF3810 CXR48_RS08975 d7dafffd47409a87e646abbf5dcf1ed2 95 SUPERFAMILY SSF89360 1 85 4.97E-11 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CXR48_RS08975 d7dafffd47409a87e646abbf5dcf1ed2 95 Gene3D G3DSA:2.60.300.12 1 94 1.0E-11 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CXR48_RS08975 d7dafffd47409a87e646abbf5dcf1ed2 95 PIRSF PIRSF034852 1 95 1.5E-39 T 29-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 SUPERFAMILY SSF51338 11 70 5.15E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 SUPERFAMILY SSF51338 318 356 5.15E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 Gene3D G3DSA:3.20.20.140 75 228 1.1E-14 T 29-03-2018 CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 SUPERFAMILY SSF51556 70 318 1.59E-43 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 TIGRFAM TIGR01178 ade: adenine deaminase 20 575 1.3E-236 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 Pfam PF01979 Amidohydrolase family 66 349 1.8E-41 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 Gene3D G3DSA:2.30.40.10 16 74 2.4E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 Hamap MF_01518 Adenine deaminase [ade]. 20 575 39.283 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 Pfam PF13382 Adenine deaminase C-terminal domain 406 572 2.6E-59 T 29-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CXR48_RS07175 d526a49b7acc96293f3c4b36f3538a71 577 Gene3D G3DSA:2.30.40.10 229 351 4.5E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS18420 7256b927f482ad49cf2828de3089dc8e 212 Pfam PF11611 Domain of unknown function (DUF4352) 78 207 6.7E-15 T 29-03-2018 IPR029051 Domain of unknown function DUF4352 CXR48_RS18420 7256b927f482ad49cf2828de3089dc8e 212 Gene3D G3DSA:2.60.40.1240 77 211 3.1E-19 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CXR48_RS19350 ab1787431c6d0dd9de13804f49f7ddb8 172 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 172 1.6E-53 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CXR48_RS19350 ab1787431c6d0dd9de13804f49f7ddb8 172 SUPERFAMILY SSF50249 1 172 1.34E-57 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS19350 ab1787431c6d0dd9de13804f49f7ddb8 172 Gene3D G3DSA:2.40.50.140 1 110 3.3E-41 T 29-03-2018 CXR48_RS19350 ab1787431c6d0dd9de13804f49f7ddb8 172 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 37.058 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CXR48_RS19350 ab1787431c6d0dd9de13804f49f7ddb8 172 Pfam PF00436 Single-strand binding protein family 2 103 7.2E-38 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CXR48_RS09465 547ba40b6813c231541f818acddb5e18 165 SUPERFAMILY SSF55729 86 150 2.34E-5 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS09465 547ba40b6813c231541f818acddb5e18 165 Gene3D G3DSA:3.40.630.30 5 162 5.6E-5 T 29-03-2018 CXR48_RS02130 6599419aa0dcda16f8851fa692b3d5b4 106 Gene3D G3DSA:3.30.70.100 1 95 7.2E-18 T 29-03-2018 CXR48_RS02130 6599419aa0dcda16f8851fa692b3d5b4 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 7.9E-13 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CXR48_RS02130 6599419aa0dcda16f8851fa692b3d5b4 106 SUPERFAMILY SSF54909 1 95 5.37E-27 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS18805 1fc6f69c8b382db6b422a8fd34fd1ac3 388 Pfam PF07690 Major Facilitator Superfamily 12 271 2.6E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS18805 1fc6f69c8b382db6b422a8fd34fd1ac3 388 Gene3D G3DSA:1.20.1250.20 1 192 2.5E-24 T 29-03-2018 CXR48_RS18805 1fc6f69c8b382db6b422a8fd34fd1ac3 388 SUPERFAMILY SSF103473 9 379 3.27E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS18805 1fc6f69c8b382db6b422a8fd34fd1ac3 388 Gene3D G3DSA:1.20.1250.20 193 388 7.2E-18 T 29-03-2018 CXR48_RS04610 942f91a180c9d08b722e3bd07dcd7034 512 Gene3D G3DSA:3.60.110.10 226 510 6.9E-54 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CXR48_RS04610 942f91a180c9d08b722e3bd07dcd7034 512 Gene3D G3DSA:3.40.630.30 7 225 2.2E-32 T 29-03-2018 CXR48_RS04610 942f91a180c9d08b722e3bd07dcd7034 512 SUPERFAMILY SSF55729 16 144 1.34E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS04610 942f91a180c9d08b722e3bd07dcd7034 512 Pfam PF00795 Carbon-nitrogen hydrolase 230 487 9.7E-31 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CXR48_RS04610 942f91a180c9d08b722e3bd07dcd7034 512 Pfam PF00583 Acetyltransferase (GNAT) family 25 147 4.6E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS04610 942f91a180c9d08b722e3bd07dcd7034 512 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 374 394 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CXR48_RS04610 942f91a180c9d08b722e3bd07dcd7034 512 SUPERFAMILY SSF56317 228 495 5.49E-59 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CXR48_RS06625 bb26e954fc645ffd8ca1dfaaa0156b37 154 Pfam PF01047 MarR family 42 99 8.6E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06625 bb26e954fc645ffd8ca1dfaaa0156b37 154 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CXR48_RS06625 bb26e954fc645ffd8ca1dfaaa0156b37 154 SUPERFAMILY SSF46785 13 144 5.94E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06625 bb26e954fc645ffd8ca1dfaaa0156b37 154 Gene3D G3DSA:1.10.10.10 10 146 3.7E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06625 bb26e954fc645ffd8ca1dfaaa0156b37 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06625 bb26e954fc645ffd8ca1dfaaa0156b37 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 2.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06625 bb26e954fc645ffd8ca1dfaaa0156b37 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06625 bb26e954fc645ffd8ca1dfaaa0156b37 154 SMART SM00347 34 134 2.5E-33 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS13545 72321aa64ca7e321937781d9736223c3 313 Pfam PF02272 DHHA1 domain 180 308 7.2E-17 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CXR48_RS13545 72321aa64ca7e321937781d9736223c3 313 Gene3D G3DSA:3.90.1640.10 1 197 7.2E-40 T 29-03-2018 CXR48_RS13545 72321aa64ca7e321937781d9736223c3 313 Pfam PF01368 DHH family 15 153 1.7E-12 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CXR48_RS13545 72321aa64ca7e321937781d9736223c3 313 SUPERFAMILY SSF64182 12 296 4.71E-72 T 29-03-2018 CXR48_RS09545 5be65c8e09d4cd6cf4eb96bfe649d22d 495 SUPERFAMILY SSF53720 12 492 1.09E-184 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS09545 5be65c8e09d4cd6cf4eb96bfe649d22d 495 Gene3D G3DSA:3.40.605.10 7 281 5.8E-114 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS09545 5be65c8e09d4cd6cf4eb96bfe649d22d 495 PIRSF PIRSF036492 43 494 1.9E-84 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CXR48_RS09545 5be65c8e09d4cd6cf4eb96bfe649d22d 495 Pfam PF00171 Aldehyde dehydrogenase family 29 489 7.4E-191 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS09545 5be65c8e09d4cd6cf4eb96bfe649d22d 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS09545 5be65c8e09d4cd6cf4eb96bfe649d22d 495 Gene3D G3DSA:3.40.309.10 282 475 3.8E-78 T 29-03-2018 CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 298 368 6.2E-25 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 SUPERFAMILY SSF101801 295 376 1.96E-24 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 SUPERFAMILY SSF103039 31 220 6.15E-51 T 29-03-2018 IPR028976 CheC-like domain CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 Pfam PF04509 CheC-like family 36 71 5.5E-15 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 Pfam PF04509 CheC-like family 132 168 5.0E-16 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 Gene3D G3DSA:2.30.330.10 284 378 1.2E-28 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 PRINTS PR00956 Flagellar motor switch protein FliN signature 344 359 1.6E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 PRINTS PR00956 Flagellar motor switch protein FliN signature 315 331 1.6E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 PRINTS PR00956 Flagellar motor switch protein FliN signature 298 314 1.6E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 PRINTS PR00956 Flagellar motor switch protein FliN signature 331 344 1.6E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 Gene3D G3DSA:3.40.1550.10 1 80 1.1E-22 T 29-03-2018 IPR028976 CheC-like domain CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 Gene3D G3DSA:3.40.1550.10 81 207 6.7E-37 T 29-03-2018 IPR028976 CheC-like domain CXR48_RS08140 8c676010691a6480ec21cc36ee7c5a77 378 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 295 370 4.6E-31 T 29-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CXR48_RS04065 e3e88e35d2eae8198502e3330f95ba6f 180 Pfam PF12867 DinB superfamily 30 168 2.3E-17 T 29-03-2018 IPR024775 DinB-like domain CXR48_RS04065 e3e88e35d2eae8198502e3330f95ba6f 180 Gene3D G3DSA:1.20.120.450 1 178 1.1E-40 T 29-03-2018 CXR48_RS04065 e3e88e35d2eae8198502e3330f95ba6f 180 Hamap MF_01256 Putative metal-dependent hydrolase . 4 178 37.557 T 29-03-2018 IPR023774 Putative metal-dependent hydrolase YfiT CXR48_RS04065 e3e88e35d2eae8198502e3330f95ba6f 180 SUPERFAMILY SSF109854 7 177 6.72E-51 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CXR48_RS16350 60885baac2814eb0099952c2ffa717d4 321 Gene3D G3DSA:3.40.50.720 2 112 1.4E-28 T 29-03-2018 CXR48_RS16350 60885baac2814eb0099952c2ffa717d4 321 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 196 218 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CXR48_RS16350 60885baac2814eb0099952c2ffa717d4 321 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 175 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CXR48_RS16350 60885baac2814eb0099952c2ffa717d4 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 286 1.9E-66 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CXR48_RS16350 60885baac2814eb0099952c2ffa717d4 321 Gene3D G3DSA:3.40.50.720 113 289 3.8E-56 T 29-03-2018 CXR48_RS16350 60885baac2814eb0099952c2ffa717d4 321 SUPERFAMILY SSF52283 2 130 4.46E-30 T 29-03-2018 CXR48_RS16350 60885baac2814eb0099952c2ffa717d4 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 316 4.9E-29 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CXR48_RS16350 60885baac2814eb0099952c2ffa717d4 321 SUPERFAMILY SSF51735 99 287 1.3E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 Pfam PF00248 Aldo/keto reductase family 32 262 4.0E-54 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 Gene3D G3DSA:3.20.20.100 2 275 3.1E-104 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 PRINTS PR00069 Aldo-keto reductase signature 126 143 1.6E-53 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 PRINTS PR00069 Aldo-keto reductase signature 96 114 1.6E-53 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 PRINTS PR00069 Aldo-keto reductase signature 197 221 1.6E-53 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 PRINTS PR00069 Aldo-keto reductase signature 40 64 1.6E-53 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 PRINTS PR00069 Aldo-keto reductase signature 160 189 1.6E-53 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 PIRSF PIRSF000097 115 272 7.5E-54 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 PIRSF PIRSF000097 2 120 1.7E-40 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 44 61 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS15675 ba439c6412af088a34ac485e1311cbc0 276 SUPERFAMILY SSF51430 7 268 3.27E-96 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS11115 f9f67d24f742c2250e99218f99eb3d64 206 Gene3D G3DSA:2.60.480.10 2 92 2.0E-23 T 29-03-2018 CXR48_RS11115 f9f67d24f742c2250e99218f99eb3d64 206 Pfam PF12164 Stage V sporulation protein AA 4 88 7.5E-20 T 29-03-2018 IPR021997 Stage V sporulation protein AA CXR48_RS05635 c95fb93d1deaa88ba6d3fda1506457e6 395 SUPERFAMILY SSF51445 124 252 2.81E-6 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS05635 c95fb93d1deaa88ba6d3fda1506457e6 395 Pfam PF13200 Putative glycosyl hydrolase domain 64 386 1.8E-128 T 29-03-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 CXR48_RS05635 c95fb93d1deaa88ba6d3fda1506457e6 395 Gene3D G3DSA:3.20.20.70 65 333 1.2E-11 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS00300 4db241ce114883e65fe5b13363a7abdc 285 Gene3D G3DSA:1.10.10.10 1 73 1.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS00300 4db241ce114883e65fe5b13363a7abdc 285 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 3.2E-31 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CXR48_RS00300 4db241ce114883e65fe5b13363a7abdc 285 SUPERFAMILY SSF46785 2 73 1.2E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS00300 4db241ce114883e65fe5b13363a7abdc 285 Gene3D G3DSA:3.40.50.2020 74 274 1.9E-34 T 29-03-2018 CXR48_RS00300 4db241ce114883e65fe5b13363a7abdc 285 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 270 6.0E-136 T 29-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CXR48_RS00300 4db241ce114883e65fe5b13363a7abdc 285 SUPERFAMILY SSF53271 93 264 7.67E-42 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS00300 4db241ce114883e65fe5b13363a7abdc 285 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 74 8.0E-32 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CXR48_RS00300 4db241ce114883e65fe5b13363a7abdc 285 Pfam PF00156 Phosphoribosyl transferase domain 108 244 7.8E-22 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CXR48_RS00740 f93a9cffb3084fa85334cbdf03bebf91 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 2.1E-83 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00740 f93a9cffb3084fa85334cbdf03bebf91 207 Gene3D G3DSA:3.40.1370.10 2 145 3.8E-58 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CXR48_RS00740 f93a9cffb3084fa85334cbdf03bebf91 207 Gene3D G3DSA:3.40.1370.10 146 205 3.1E-16 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CXR48_RS00740 f93a9cffb3084fa85334cbdf03bebf91 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 1.1E-72 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CXR48_RS00740 f93a9cffb3084fa85334cbdf03bebf91 207 SUPERFAMILY SSF52166 1 206 4.19E-84 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CXR48_RS00740 f93a9cffb3084fa85334cbdf03bebf91 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 37.893 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12960 f9b4648b10218f61ffbd4cd6e31452a1 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 427 104.166 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CXR48_RS12960 f9b4648b10218f61ffbd4cd6e31452a1 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS12960 f9b4648b10218f61ffbd4cd6e31452a1 429 SUPERFAMILY SSF53383 4 425 1.19E-130 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS12960 f9b4648b10218f61ffbd4cd6e31452a1 429 Pfam PF00202 Aminotransferase class-III 34 397 2.7E-74 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS12960 f9b4648b10218f61ffbd4cd6e31452a1 429 Gene3D G3DSA:3.90.1150.10 315 429 1.1E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS12960 f9b4648b10218f61ffbd4cd6e31452a1 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 426 1.2E-202 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CXR48_RS12960 f9b4648b10218f61ffbd4cd6e31452a1 429 Gene3D G3DSA:3.90.1150.10 1 169 3.6E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS12960 f9b4648b10218f61ffbd4cd6e31452a1 429 Gene3D G3DSA:3.40.640.10 175 314 1.7E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS19270 303c47eb2f5bbdaa258fe719503f961d 75 Gene3D G3DSA:1.10.260.40 1 74 8.3E-12 T 29-03-2018 CXR48_RS19270 303c47eb2f5bbdaa258fe719503f961d 75 Pfam PF01381 Helix-turn-helix 1 30 1.1E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS19270 303c47eb2f5bbdaa258fe719503f961d 75 SUPERFAMILY SSF47413 1 37 9.01E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS01575 4877391cd98c6695fee5938f5f306b59 400 ProSitePatterns PS00217 Sugar transport proteins signature 2. 108 133 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS01575 4877391cd98c6695fee5938f5f306b59 400 Gene3D G3DSA:1.20.1250.20 7 201 7.3E-36 T 29-03-2018 CXR48_RS01575 4877391cd98c6695fee5938f5f306b59 400 Gene3D G3DSA:1.20.1250.20 212 400 1.4E-27 T 29-03-2018 CXR48_RS01575 4877391cd98c6695fee5938f5f306b59 400 SUPERFAMILY SSF103473 8 397 9.16E-82 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01575 4877391cd98c6695fee5938f5f306b59 400 Pfam PF07690 Major Facilitator Superfamily 21 265 2.5E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 SUPERFAMILY SSF56784 333 353 3.35E-55 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 SUPERFAMILY SSF56784 407 632 3.35E-55 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 SUPERFAMILY SSF81653 137 234 5.23E-27 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 SUPERFAMILY SSF81665 582 613 4.18E-16 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 SUPERFAMILY SSF81665 86 138 4.18E-16 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 SUPERFAMILY SSF81665 235 329 4.18E-16 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 547 1.1E-37 T 29-03-2018 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 Gene3D G3DSA:2.70.150.10 3 235 4.0E-36 T 29-03-2018 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 107 612 8.9E-85 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 Gene3D G3DSA:3.40.50.1000 460 600 3.5E-44 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00941 Cadmium-transporting ATPase signature 47 64 2.3E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00941 Cadmium-transporting ATPase signature 64 76 2.3E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00941 Cadmium-transporting ATPase signature 119 139 2.3E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00941 Cadmium-transporting ATPase signature 200 216 2.3E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00941 Cadmium-transporting ATPase signature 219 233 2.3E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 84 635 1.7E-182 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 Pfam PF00122 E1-E2 ATPase 134 313 3.2E-50 T 29-03-2018 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 Gene3D G3DSA:3.40.1110.10 346 459 6.0E-25 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 184 198 1.8E-30 T 29-03-2018 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 490 1.8E-30 T 29-03-2018 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 568 1.8E-30 T 29-03-2018 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 1.8E-30 T 29-03-2018 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 552 1.8E-30 T 29-03-2018 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 469 1.8E-30 T 29-03-2018 CXR48_RS06850 05e8cb4b1c908c61c6f191782d31ffe7 637 ProSitePatterns PS01229 Hypothetical cof family signature 2. 533 555 - T 29-03-2018 CXR48_RS06060 92f8d3736fef858bfde96f10b1c766ad 165 Gene3D G3DSA:2.60.120.10 27 148 1.6E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS06060 92f8d3736fef858bfde96f10b1c766ad 165 PIRSF PIRSF019307 1 165 4.8E-60 T 29-03-2018 IPR014500 Uncharacterised conserved protein UCP019307, cupin-type CXR48_RS06060 92f8d3736fef858bfde96f10b1c766ad 165 SUPERFAMILY SSF51182 10 128 1.89E-17 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS06060 92f8d3736fef858bfde96f10b1c766ad 165 Pfam PF07883 Cupin domain 55 107 4.1E-8 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CXR48_RS00680 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Gene3D G3DSA:3.30.1390.10 53 123 3.0E-31 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CXR48_RS00680 4b262c4e56ac9c79fea9c34bb4db9fd5 123 SUPERFAMILY SSF54736 52 123 1.05E-24 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CXR48_RS00680 4b262c4e56ac9c79fea9c34bb4db9fd5 123 SUPERFAMILY SSF48300 4 58 3.92E-16 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00680 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Gene3D G3DSA:1.20.5.710 3 52 1.2E-14 T 29-03-2018 CXR48_RS00680 4b262c4e56ac9c79fea9c34bb4db9fd5 123 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 58 96 7.0E-15 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00680 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 57 123 2.1E-30 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00680 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 123 25.469 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00680 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 5.1E-20 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00680 4b262c4e56ac9c79fea9c34bb4db9fd5 123 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 123 1.3E-51 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS14030 3c9be1aa9c9d343d7875c298e228f842 334 SUPERFAMILY SSF55874 175 323 8.12E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14030 3c9be1aa9c9d343d7875c298e228f842 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 280 6.7E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14030 3c9be1aa9c9d343d7875c298e228f842 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 323 6.7E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14030 3c9be1aa9c9d343d7875c298e228f842 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 252 266 6.7E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14030 3c9be1aa9c9d343d7875c298e228f842 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 304 6.7E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14030 3c9be1aa9c9d343d7875c298e228f842 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 325 4.7E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14030 3c9be1aa9c9d343d7875c298e228f842 334 Gene3D G3DSA:3.30.565.10 147 324 8.6E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14030 3c9be1aa9c9d343d7875c298e228f842 334 SMART SM00387 216 326 7.6E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS04755 627f3470408aba2753c30a05df81c5f1 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 99 119 1.1E-11 T 29-03-2018 CXR48_RS04755 627f3470408aba2753c30a05df81c5f1 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 234 258 1.1E-11 T 29-03-2018 CXR48_RS04755 627f3470408aba2753c30a05df81c5f1 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 166 190 1.1E-11 T 29-03-2018 CXR48_RS04755 627f3470408aba2753c30a05df81c5f1 394 Gene3D G3DSA:3.90.1150.10 254 394 2.1E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS04755 627f3470408aba2753c30a05df81c5f1 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 240 253 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CXR48_RS04755 627f3470408aba2753c30a05df81c5f1 394 Gene3D G3DSA:3.40.640.10 53 253 8.3E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS04755 627f3470408aba2753c30a05df81c5f1 394 Pfam PF00155 Aminotransferase class I and II 38 379 2.3E-53 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS04755 627f3470408aba2753c30a05df81c5f1 394 SUPERFAMILY SSF53383 30 388 1.51E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 PRINTS PR00171 Sugar transporter signature 101 120 6.3E-27 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 PRINTS PR00171 Sugar transporter signature 253 263 6.3E-27 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 PRINTS PR00171 Sugar transporter signature 365 377 6.3E-27 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 PRINTS PR00171 Sugar transporter signature 18 28 6.3E-27 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 PRINTS PR00171 Sugar transporter signature 342 363 6.3E-27 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 Gene3D G3DSA:1.20.1250.20 4 201 8.2E-37 T 29-03-2018 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 5 437 3.4E-116 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 SUPERFAMILY SSF103473 5 438 2.09E-82 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 ProSitePatterns PS00216 Sugar transport proteins signature 1. 297 314 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 81 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 Pfam PF00083 Sugar (and other) transporter 13 439 2.5E-122 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CXR48_RS18745 c9e6aeeac7da0b921fef0442f8294924 462 Gene3D G3DSA:1.20.1250.20 217 454 5.6E-43 T 29-03-2018 CXR48_RS03055 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Gene3D G3DSA:3.40.50.720 73 186 1.2E-15 T 29-03-2018 CXR48_RS03055 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Pfam PF06971 Putative DNA-binding protein N-terminus 7 55 1.4E-19 T 29-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CXR48_RS03055 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 SMART SM00881 81 180 4.2E-15 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CXR48_RS03055 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Gene3D G3DSA:1.10.10.10 6 72 1.1E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03055 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Pfam PF02629 CoA binding domain 83 178 1.9E-28 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CXR48_RS03055 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 209 37.711 T 29-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CXR48_RS03055 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 SUPERFAMILY SSF46785 9 80 2.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03055 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 SUPERFAMILY SSF51735 84 207 2.07E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 Pfam PF08245 Mur ligase middle domain 46 274 4.8E-17 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 TIGRFAM TIGR01499 folC: bifunctional protein FolC 25 428 9.9E-131 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 Pfam PF02875 Mur ligase family, glutamate ligase domain 299 378 7.5E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 SUPERFAMILY SSF53244 301 429 5.13E-27 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 Gene3D G3DSA:3.90.190.20 301 430 4.2E-23 T 29-03-2018 CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 SUPERFAMILY SSF53623 4 299 2.29E-92 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 Gene3D G3DSA:3.40.1190.10 3 300 5.1E-84 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 67 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CXR48_RS12935 60ad9df1b490b73c790e5d0328e071e1 430 PIRSF PIRSF001563 1 430 9.0E-158 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CXR48_RS07155 50c0840c730fd41a3e917ceb48f63bee 94 SUPERFAMILY SSF89447 1 51 3.92E-15 T 29-03-2018 CXR48_RS07155 50c0840c730fd41a3e917ceb48f63bee 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 2.4E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS07155 50c0840c730fd41a3e917ceb48f63bee 94 Gene3D G3DSA:2.10.260.10 1 48 6.7E-17 T 29-03-2018 CXR48_RS07155 50c0840c730fd41a3e917ceb48f63bee 94 SMART SM00966 8 51 1.3E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS16980 b6197b12a1647c6f27ce4e694d9c302b 255 Gene3D G3DSA:3.30.1330.80 110 216 5.6E-44 T 29-03-2018 CXR48_RS16980 b6197b12a1647c6f27ce4e694d9c302b 255 Gene3D G3DSA:3.30.1330.80 19 109 2.3E-30 T 29-03-2018 CXR48_RS16980 b6197b12a1647c6f27ce4e694d9c302b 255 Pfam PF03306 Alpha-acetolactate decarboxylase 22 239 6.3E-82 T 29-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CXR48_RS16980 b6197b12a1647c6f27ce4e694d9c302b 255 SUPERFAMILY SSF117856 20 251 6.28E-85 T 29-03-2018 CXR48_RS16980 b6197b12a1647c6f27ce4e694d9c302b 255 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 21 251 9.7E-105 T 29-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CXR48_RS16980 b6197b12a1647c6f27ce4e694d9c302b 255 PIRSF PIRSF001332 3 252 6.8E-98 T 29-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CXR48_RS14910 9c7ef4921f05e29049f3b6f6f0806ac5 198 Gene3D G3DSA:3.90.420.10 5 197 5.6E-53 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CXR48_RS14910 9c7ef4921f05e29049f3b6f6f0806ac5 198 SUPERFAMILY SSF56524 12 198 6.8E-62 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CXR48_RS14910 9c7ef4921f05e29049f3b6f6f0806ac5 198 Pfam PF00174 Oxidoreductase molybdopterin binding domain 32 178 7.6E-38 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CXR48_RS07995 42dbf36198f6a93519c15d8733524d56 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 113 6.6E-53 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07995 42dbf36198f6a93519c15d8733524d56 115 PIRSF PIRSF002191 1 115 6.4E-52 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07995 42dbf36198f6a93519c15d8733524d56 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS07995 42dbf36198f6a93519c15d8733524d56 115 Pfam PF01245 Ribosomal protein L19 4 112 4.0E-54 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07995 42dbf36198f6a93519c15d8733524d56 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 32.952 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07995 42dbf36198f6a93519c15d8733524d56 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07995 42dbf36198f6a93519c15d8733524d56 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07995 42dbf36198f6a93519c15d8733524d56 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07995 42dbf36198f6a93519c15d8733524d56 115 SUPERFAMILY SSF50104 2 114 4.41E-49 T 29-03-2018 IPR008991 Translation protein SH3-like domain CXR48_RS03320 429b8448427e013be348c00ba833e514 422 Gene3D G3DSA:3.90.600.10 325 417 2.1E-31 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 Gene3D G3DSA:3.30.1490.20 85 187 4.6E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 Gene3D G3DSA:3.40.50.20 2 84 6.4E-35 T 29-03-2018 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 SMART SM01209 101 293 8.3E-131 T 29-03-2018 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 1.3E-85 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 SMART SM01210 325 417 1.3E-42 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 42.628 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 Gene3D G3DSA:3.30.470.20 189 323 4.2E-57 T 29-03-2018 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 4.9E-32 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 SUPERFAMILY SSF51246 324 417 2.43E-27 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 SUPERFAMILY SSF52440 2 101 5.75E-33 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS03320 429b8448427e013be348c00ba833e514 422 SUPERFAMILY SSF56059 102 322 7.07E-62 T 29-03-2018 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 417 2.4E-173 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS03320 429b8448427e013be348c00ba833e514 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 326 415 4.5E-26 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CXR48_RS08300 62a42f152c792968fab7d7ea889cf568 92 SUPERFAMILY SSF103007 3 92 1.16E-31 T 29-03-2018 IPR007546 Protein of unknown function DUF503 CXR48_RS08300 62a42f152c792968fab7d7ea889cf568 92 Pfam PF04456 Protein of unknown function (DUF503) 2 87 2.5E-31 T 29-03-2018 IPR007546 Protein of unknown function DUF503 CXR48_RS08300 62a42f152c792968fab7d7ea889cf568 92 Gene3D G3DSA:3.30.70.1120 1 91 1.1E-31 T 29-03-2018 CXR48_RS04920 eb461aab16cea778cffd52cc972c31d7 298 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS04920 eb461aab16cea778cffd52cc972c31d7 298 SMART SM00382 26 205 1.2E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04920 eb461aab16cea778cffd52cc972c31d7 298 Pfam PF13732 Domain of unknown function (DUF4162) 211 293 5.5E-21 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 CXR48_RS04920 eb461aab16cea778cffd52cc972c31d7 298 Gene3D G3DSA:3.40.50.300 1 260 6.0E-60 T 29-03-2018 CXR48_RS04920 eb461aab16cea778cffd52cc972c31d7 298 Pfam PF00005 ABC transporter 17 157 2.7E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS04920 eb461aab16cea778cffd52cc972c31d7 298 SUPERFAMILY SSF52540 2 224 4.26E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS06220 d5fa4eb04ca7bb8d2f71a3771d4cd629 67 ProDom PD027572 XTRA PBSX RELATED YQAO ELEMENT PHAGE PHAGE-LIKE 9 61 6.0E-19 T 29-03-2018 IPR035530 Phage-like element PBSX protein XtrA CXR48_RS06220 d5fa4eb04ca7bb8d2f71a3771d4cd629 67 Pfam PF17356 Phage-like element PBSX protein XtrA 2 66 1.8E-21 T 29-03-2018 IPR035530 Phage-like element PBSX protein XtrA CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Pfam PF00550 Phosphopantetheine attachment site 429 492 1.0E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Pfam PF00550 Phosphopantetheine attachment site 326 390 7.4E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SMART SM00823 Phosphopantetheine attachment site 425 497 1.3E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SMART SM00823 Phosphopantetheine attachment site 323 394 0.0018 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 755 940 1.9E-39 T 29-03-2018 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SUPERFAMILY SSF51735 752 959 6.35E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Gene3D G3DSA:1.10.1200.10 301 399 6.5E-14 T 29-03-2018 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Gene3D G3DSA:1.10.1200.10 402 506 1.9E-15 T 29-03-2018 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SUPERFAMILY SSF53901 1417 1438 3.17E-94 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SUPERFAMILY SSF53901 1015 1377 3.17E-94 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1018 1263 5.0E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SUPERFAMILY SSF47336 319 394 1.44E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1271 1384 6.9E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Gene3D G3DSA:3.40.47.10 1013 1275 3.1E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1388 1501 3.7E-10 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Gene3D G3DSA:3.40.47.10 1278 1440 9.3E-53 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SUPERFAMILY SSF47336 426 497 6.02E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SMART SM00825 Beta-ketoacyl synthase 1020 1442 8.9E-190 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Gene3D G3DSA:3.40.50.720 748 1012 3.2E-43 T 29-03-2018 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 SMART SM01294 427 493 0.0021 T 29-03-2018 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Pfam PF08659 KR domain 755 939 1.1E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07245 eb5cfdc2d5743714a16296b26de1bf95 1903 Pfam PF14765 Polyketide synthase dehydratase 9 285 4.9E-24 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 2.5E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 SUPERFAMILY SSF53822 93 371 2.16E-61 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 Gene3D G3DSA:3.40.50.2300 88 204 1.5E-22 T 29-03-2018 CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 SUPERFAMILY SSF46785 15 84 4.02E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 Gene3D G3DSA:3.40.50.2300 205 373 6.4E-36 T 29-03-2018 CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 Gene3D G3DSA:1.10.10.10 8 82 3.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 SMART SM00345 21 80 5.2E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 3.9E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 3.9E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16050 5a3f327bcb36937f1ba74c3210a31e86 375 Pfam PF13377 Periplasmic binding protein-like domain 207 370 1.4E-31 T 29-03-2018 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 Gene3D G3DSA:3.40.1160.10 1 263 1.4E-59 T 29-03-2018 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 Pfam PF00696 Amino acid kinase family 4 232 7.7E-47 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 361 7.0E-143 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 SMART SM00359 277 356 4.7E-15 T 29-03-2018 IPR002478 PUA domain GO:0003723 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 258 37.007 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 PIRSF PIRSF000729 1 364 3.5E-133 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 Pfam PF01472 PUA domain 277 346 5.3E-17 T 29-03-2018 IPR002478 PUA domain GO:0003723 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 SUPERFAMILY SSF88697 277 361 1.31E-15 T 29-03-2018 IPR015947 PUA-like domain CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 SUPERFAMILY SSF53633 4 254 1.2E-69 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 2.6E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 2.6E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 2.6E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 2.6E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 2.6E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS06505 b740b860a73256e3ed5c3ecfda5d8d69 370 Gene3D G3DSA:2.30.130.10 275 362 2.3E-18 T 29-03-2018 IPR002478 PUA domain GO:0003723 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Gene3D G3DSA:3.30.70.870 305 402 2.5E-34 T 29-03-2018 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 SUPERFAMILY SSF54980 400 515 1.1E-29 T 29-03-2018 IPR035647 EF-G domain III/V-like CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Pfam PF14492 Elongation Factor G, domain II 330 379 9.8E-7 T 29-03-2018 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 PRINTS PR00315 GTP-binding elongation factor signature 89 100 3.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 PRINTS PR00315 GTP-binding elongation factor signature 125 134 3.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 PRINTS PR00315 GTP-binding elongation factor signature 9 22 3.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 PRINTS PR00315 GTP-binding elongation factor signature 53 61 3.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 PRINTS PR00315 GTP-binding elongation factor signature 73 83 3.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Pfam PF00679 Elongation factor G C-terminus 399 479 5.6E-25 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Gene3D G3DSA:3.40.50.300 2 69 4.4E-10 T 29-03-2018 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 SUPERFAMILY SSF54980 304 389 1.22E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 146 1.6E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 2.5E-56 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Gene3D G3DSA:2.40.30.10 194 304 2.1E-22 T 29-03-2018 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 SUPERFAMILY SSF50447 154 301 1.29E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 SUPERFAMILY SSF52540 3 208 6.64E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Gene3D G3DSA:3.40.50.300 70 193 5.3E-31 T 29-03-2018 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Gene3D G3DSA:3.30.70.240 403 484 3.7E-20 T 29-03-2018 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Pfam PF03144 Elongation factor Tu domain 2 221 291 6.6E-14 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 Gene3D G3DSA:2.40.50.250 485 575 2.7E-37 T 29-03-2018 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 601 1.5E-290 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CXR48_RS07360 1eb48868b81ab441825d26db0f818e3b 612 SMART SM00838 397 485 5.4E-5 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CXR48_RS12375 28d079d91e9ce2249096a943d9a1db45 418 Gene3D G3DSA:1.20.1250.20 1 195 2.7E-14 T 29-03-2018 CXR48_RS12375 28d079d91e9ce2249096a943d9a1db45 418 Gene3D G3DSA:1.20.1250.20 208 414 2.0E-17 T 29-03-2018 CXR48_RS12375 28d079d91e9ce2249096a943d9a1db45 418 SUPERFAMILY SSF103473 1 405 1.83E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS12375 28d079d91e9ce2249096a943d9a1db45 418 Pfam PF07690 Major Facilitator Superfamily 16 362 1.6E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS19310 1eb888a202268efb56b59d90c0aa570a 298 Pfam PF02517 CAAX protease self-immunity 142 240 3.3E-11 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CXR48_RS03865 5a98096caf320cc56d56d848640617bb 397 SUPERFAMILY SSF103473 6 392 1.7E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS03865 5a98096caf320cc56d56d848640617bb 397 Gene3D G3DSA:1.20.1250.20 1 198 2.3E-27 T 29-03-2018 CXR48_RS03865 5a98096caf320cc56d56d848640617bb 397 Pfam PF07690 Major Facilitator Superfamily 13 299 1.7E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS03865 5a98096caf320cc56d56d848640617bb 397 Gene3D G3DSA:1.20.1250.20 204 389 1.4E-19 T 29-03-2018 CXR48_RS16560 4afb1c2d492712110e83c2f5a8e7eb26 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 2.0E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS16560 4afb1c2d492712110e83c2f5a8e7eb26 208 Gene3D G3DSA:1.10.357.10 58 202 3.5E-9 T 29-03-2018 CXR48_RS16560 4afb1c2d492712110e83c2f5a8e7eb26 208 Gene3D G3DSA:1.10.10.60 3 35 2.1E-11 T 29-03-2018 CXR48_RS16560 4afb1c2d492712110e83c2f5a8e7eb26 208 Gene3D G3DSA:1.10.260.40 36 57 0.0021 T 29-03-2018 CXR48_RS16560 4afb1c2d492712110e83c2f5a8e7eb26 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 9.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS16560 4afb1c2d492712110e83c2f5a8e7eb26 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 9.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS16560 4afb1c2d492712110e83c2f5a8e7eb26 208 SUPERFAMILY SSF46689 4 66 5.64E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS18170 d6acdccd378b7b9e0112092875bf2691 64 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 2 62 1.5E-32 T 29-03-2018 IPR019240 Protein of unknown function DUF2196 CXR48_RS18170 d6acdccd378b7b9e0112092875bf2691 64 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 2 62 4.6E-34 T 29-03-2018 IPR019240 Protein of unknown function DUF2196 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 Gene3D G3DSA:1.10.1040.10 245 321 1.7E-29 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 27 429 1.9E-121 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 225 315 1.5E-27 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 SUPERFAMILY SSF51735 27 218 2.57E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 27 204 3.0E-39 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 SMART SM00984 337 433 6.1E-25 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 SUPERFAMILY SSF48179 224 317 1.87E-28 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 PIRSF PIRSF000124 25 444 2.3E-57 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 PIRSF PIRSF500136 16 443 8.4E-137 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 SUPERFAMILY SSF52413 332 433 1.07E-22 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 Gene3D G3DSA:3.40.50.720 20 222 2.2E-35 T 29-03-2018 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 337 432 1.3E-20 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 Gene3D G3DSA:1.20.5.170 224 244 1.9E-10 T 29-03-2018 CXR48_RS16000 d38b8f57fb3b28ee13f90ca7e614025d 444 Gene3D G3DSA:3.40.50.720 327 436 5.2E-22 T 29-03-2018 CXR48_RS01840 05eca562f136836a821ded85edb85504 204 SUPERFAMILY SSF52507 13 196 8.24E-62 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CXR48_RS01840 05eca562f136836a821ded85edb85504 204 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 13 196 37.289 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CXR48_RS01840 05eca562f136836a821ded85edb85504 204 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 14 194 1.6E-88 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CXR48_RS01840 05eca562f136836a821ded85edb85504 204 Pfam PF02441 Flavoprotein 13 175 3.9E-27 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CXR48_RS01840 05eca562f136836a821ded85edb85504 204 Gene3D G3DSA:3.40.50.1950 13 203 8.8E-56 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CXR48_RS01840 05eca562f136836a821ded85edb85504 204 Hamap MF_01986 Probable UbiX-like flavin prenyltransferase. 13 200 50.545 T 29-03-2018 IPR032901 Probable UbiX-like flavin prenyltransferase CXR48_RS14130 b47f6df8c8bb9f5c158ea6c85a9736ba 632 Gene3D G3DSA:3.60.20.10 1 222 4.4E-56 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS14130 b47f6df8c8bb9f5c158ea6c85a9736ba 632 PIRSF PIRSF001589 1 628 5.6E-196 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CXR48_RS14130 b47f6df8c8bb9f5c158ea6c85a9736ba 632 Pfam PF13537 Glutamine amidotransferase domain 51 168 6.3E-45 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CXR48_RS14130 b47f6df8c8bb9f5c158ea6c85a9736ba 632 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 4.0E-182 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CXR48_RS14130 b47f6df8c8bb9f5c158ea6c85a9736ba 632 SUPERFAMILY SSF56235 1 222 6.52E-60 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS14130 b47f6df8c8bb9f5c158ea6c85a9736ba 632 SUPERFAMILY SSF52402 467 605 3.94E-87 T 29-03-2018 CXR48_RS14130 b47f6df8c8bb9f5c158ea6c85a9736ba 632 SUPERFAMILY SSF52402 228 380 3.94E-87 T 29-03-2018 CXR48_RS14130 b47f6df8c8bb9f5c158ea6c85a9736ba 632 Pfam PF00733 Asparagine synthase 240 610 7.6E-112 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CXR48_RS14130 b47f6df8c8bb9f5c158ea6c85a9736ba 632 Gene3D G3DSA:3.40.50.620 223 617 5.6E-82 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS13765 05f99b375d7c464e3fb2dacd79675e5f 572 Pfam PF00501 AMP-binding enzyme 51 462 6.0E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS13765 05f99b375d7c464e3fb2dacd79675e5f 572 Gene3D G3DSA:3.40.50.980 218 371 2.5E-40 T 29-03-2018 CXR48_RS13765 05f99b375d7c464e3fb2dacd79675e5f 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 549 7.5E-24 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS13765 05f99b375d7c464e3fb2dacd79675e5f 572 Gene3D G3DSA:3.30.300.30 458 570 5.4E-27 T 29-03-2018 CXR48_RS13765 05f99b375d7c464e3fb2dacd79675e5f 572 SUPERFAMILY SSF56801 15 562 2.49E-158 T 29-03-2018 CXR48_RS13765 05f99b375d7c464e3fb2dacd79675e5f 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS13765 05f99b375d7c464e3fb2dacd79675e5f 572 Gene3D G3DSA:2.30.38.10 372 455 8.3E-22 T 29-03-2018 CXR48_RS13765 05f99b375d7c464e3fb2dacd79675e5f 572 Gene3D G3DSA:3.40.50.980 41 217 2.6E-37 T 29-03-2018 CXR48_RS03285 de85513c871176796b1c96b776342624 84 SUPERFAMILY SSF82697 1 80 1.53E-30 T 29-03-2018 CXR48_RS03285 de85513c871176796b1c96b776342624 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 9.5E-39 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS03285 de85513c871176796b1c96b776342624 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 8.4E-34 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS03285 de85513c871176796b1c96b776342624 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 80 2.0E-35 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS03285 de85513c871176796b1c96b776342624 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 22.211 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS03285 de85513c871176796b1c96b776342624 84 Gene3D G3DSA:3.30.1280.10 2 79 7.8E-33 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 SUPERFAMILY SSF55781 108 177 1.63E-5 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 2.9E-90 T 29-03-2018 IPR014213 Sporulation stage V, protein T CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 Gene3D G3DSA:3.30.450.40 35 178 3.9E-6 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 Gene3D G3DSA:2.10.260.10 1 34 2.5E-20 T 29-03-2018 CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 29-03-2018 CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 2.3E-46 T 29-03-2018 CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 SMART SM00966 8 52 1.1E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS00345 59ad887476deac092d5bd9c291a75a5c 178 PIRSF PIRSF026579 1 178 1.3E-96 T 29-03-2018 IPR014213 Sporulation stage V, protein T CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 SUPERFAMILY SSF46557 6 80 5.23E-28 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 SUPERFAMILY SSF54534 84 156 1.57E-21 T 29-03-2018 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 85 157 5.5E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 2.4E-32 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 PIRSF PIRSF006092 1 157 5.1E-52 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 157 3.1E-59 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 Gene3D G3DSA:3.10.50.30 78 157 5.8E-26 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 157 33.702 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CXR48_RS12570 43f4af10a922eb624f7c37a50e0fd373 157 Gene3D G3DSA:1.10.287.180 6 77 3.7E-33 T 29-03-2018 CXR48_RS14560 422e21ce14f479cf971728201f0f7228 134 SUPERFAMILY SSF160755 1 132 1.96E-35 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CXR48_RS14560 422e21ce14f479cf971728201f0f7228 134 Gene3D G3DSA:3.30.310.100 1 116 1.9E-40 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CXR48_RS14560 422e21ce14f479cf971728201f0f7228 134 Pfam PF08868 YugN-like family 4 132 5.2E-50 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CXR48_RS14535 71e946be76ca4c6c6116956111a1c892 429 SUPERFAMILY SSF54631 204 338 1.09E-33 T 29-03-2018 CXR48_RS14535 71e946be76ca4c6c6116956111a1c892 429 Gene3D G3DSA:3.30.465.10 342 428 4.0E-20 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS14535 71e946be76ca4c6c6116956111a1c892 429 Gene3D G3DSA:3.10.580.10 195 341 4.0E-33 T 29-03-2018 CXR48_RS14535 71e946be76ca4c6c6116956111a1c892 429 Pfam PF01595 Domain of unknown function DUF21 7 201 8.3E-48 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CXR48_RS14535 71e946be76ca4c6c6116956111a1c892 429 Pfam PF00571 CBS domain 218 272 5.5E-8 T 29-03-2018 IPR000644 CBS domain CXR48_RS14535 71e946be76ca4c6c6116956111a1c892 429 Pfam PF00571 CBS domain 284 335 7.0E-7 T 29-03-2018 IPR000644 CBS domain CXR48_RS14535 71e946be76ca4c6c6116956111a1c892 429 Pfam PF03471 Transporter associated domain 352 427 1.7E-16 T 29-03-2018 IPR005170 Transporter-associated domain CXR48_RS14535 71e946be76ca4c6c6116956111a1c892 429 SUPERFAMILY SSF56176 349 427 7.63E-16 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS14535 71e946be76ca4c6c6116956111a1c892 429 SMART SM01091 351 428 1.5E-20 T 29-03-2018 IPR005170 Transporter-associated domain CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 56 1.2E-23 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 84 99 1.2E-23 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 112 127 1.2E-23 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 99 111 1.2E-23 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 18 33 1.2E-23 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 PIRSF PIRSF001467 1 142 6.8E-41 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 39 56 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 Gene3D G3DSA:2.40.100.10 2 142 6.2E-50 T 29-03-2018 IPR029000 Cyclophilin-like domain CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 6 135 4.2E-41 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CXR48_RS11070 0917ed91c3f5e6954ed48a68ebea3673 143 SUPERFAMILY SSF50891 7 137 4.53E-47 T 29-03-2018 IPR029000 Cyclophilin-like domain CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 SUPERFAMILY SSF54814 2 105 3.92E-39 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 6.7E-39 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 SMART SM00322 59 124 9.9E-9 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.263 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 Pfam PF07650 KH domain 37 109 1.7E-21 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 Gene3D G3DSA:3.30.300.20 17 106 1.8E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 SUPERFAMILY SSF54821 107 205 2.09E-37 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.4E-96 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CXR48_RS00765 c1f910591b92bdc63982b5cae04386f7 218 Gene3D G3DSA:3.30.1140.32 107 206 1.5E-35 T 29-03-2018 CXR48_RS16780 353ea6984652933f26291e54f05d36e7 496 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 322 492 5.7E-51 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS16780 353ea6984652933f26291e54f05d36e7 496 SUPERFAMILY SSF53187 319 495 2.07E-51 T 29-03-2018 CXR48_RS16780 353ea6984652933f26291e54f05d36e7 496 SMART SM00646 380 492 1.1E-41 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS16780 353ea6984652933f26291e54f05d36e7 496 Gene3D G3DSA:3.40.630.40 317 496 1.9E-57 T 29-03-2018 CXR48_RS16780 353ea6984652933f26291e54f05d36e7 496 Pfam PF04122 Putative cell wall binding repeat 2 129 213 1.7E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CXR48_RS16780 353ea6984652933f26291e54f05d36e7 496 Pfam PF04122 Putative cell wall binding repeat 2 223 308 1.9E-8 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CXR48_RS16780 353ea6984652933f26291e54f05d36e7 496 Pfam PF04122 Putative cell wall binding repeat 2 30 115 1.3E-17 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CXR48_RS07700 675cf1b440020b7b1306d30490830f35 304 SMART SM00363 15 72 1.3E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS07700 675cf1b440020b7b1306d30490830f35 304 SUPERFAMILY SSF55174 15 101 1.16E-15 T 29-03-2018 CXR48_RS07700 675cf1b440020b7b1306d30490830f35 304 Gene3D G3DSA:3.30.2350.10 79 304 5.9E-75 T 29-03-2018 CXR48_RS07700 675cf1b440020b7b1306d30490830f35 304 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS07700 675cf1b440020b7b1306d30490830f35 304 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 301 3.6E-110 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS07700 675cf1b440020b7b1306d30490830f35 304 Pfam PF00849 RNA pseudouridylate synthase 88 242 1.3E-37 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS07700 675cf1b440020b7b1306d30490830f35 304 Gene3D G3DSA:3.10.290.10 1 72 5.0E-25 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS07700 675cf1b440020b7b1306d30490830f35 304 Pfam PF01479 S4 domain 15 61 1.7E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS07700 675cf1b440020b7b1306d30490830f35 304 SUPERFAMILY SSF55120 73 301 6.37E-81 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Gene3D G3DSA:3.30.54.20 148 189 2.7E-20 T 29-03-2018 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Gene3D G3DSA:3.40.50.800 540 643 2.0E-30 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 SUPERFAMILY SSF55681 245 534 5.77E-96 T 29-03-2018 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 SUPERFAMILY SSF55186 68 243 1.26E-66 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Gene3D G3DSA:3.30.980.10 68 147 2.8E-26 T 29-03-2018 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 221 1.1E-16 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 472 500 3.1E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 3.1E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 515 528 3.1E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 3.1E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 542 554 3.1E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 SUPERFAMILY SSF52954 535 638 5.29E-31 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Pfam PF02824 TGS domain 5 64 1.7E-14 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 SUPERFAMILY SSF81271 5 64 7.41E-17 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 640 2.6E-245 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Pfam PF03129 Anticodon binding domain 549 636 1.6E-25 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 643 35.284 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 SMART SM00863 172 221 2.8E-25 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 327 536 1.8E-34 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Gene3D G3DSA:3.10.20.30 2 65 3.8E-21 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS13375 499e1d13e9fc0dd6a823847625871d1f 643 Gene3D G3DSA:3.30.930.10 223 539 6.1E-104 T 29-03-2018 CXR48_RS11520 812024b2559a158e781754a0b87a2d03 330 Gene3D G3DSA:3.40.50.970 2 330 4.6E-89 T 29-03-2018 CXR48_RS11520 812024b2559a158e781754a0b87a2d03 330 Pfam PF00676 Dehydrogenase E1 component 20 320 1.2E-111 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CXR48_RS11520 812024b2559a158e781754a0b87a2d03 330 SUPERFAMILY SSF52518 8 330 3.93E-106 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 SUPERFAMILY SSF51246 331 443 1.67E-36 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 SUPERFAMILY SSF52440 2 113 1.65E-46 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 6.3E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 Gene3D G3DSA:3.30.1490.20 119 204 4.4E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 Gene3D G3DSA:3.30.470.20 205 443 1.8E-99 T 29-03-2018 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 SMART SM00878 336 441 5.1E-49 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 1.9E-77 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 SUPERFAMILY SSF56059 83 349 5.66E-66 T 29-03-2018 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 Gene3D G3DSA:3.40.50.20 1 118 2.7E-52 T 29-03-2018 CXR48_RS09205 ff3491bc17dde9557b5fb7e6649986e5 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 3.3E-34 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 SUPERFAMILY SSF88659 125 211 3.79E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 Pfam PF08281 Sigma-70, region 4 164 207 3.4E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 62 75 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 16 212 1.1E-110 T 29-03-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 SUPERFAMILY SSF88946 20 107 9.55E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 Pfam PF04542 Sigma-70 region 2 38 107 2.0E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 211 7.7E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 PIRSF PIRSF002939 3 218 3.2E-110 T 29-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 Gene3D G3DSA:1.10.1740.10 15 118 2.5E-19 T 29-03-2018 CXR48_RS00645 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 Gene3D G3DSA:1.10.10.10 140 217 5.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 Gene3D G3DSA:3.50.50.60 249 347 9.4E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 Gene3D G3DSA:3.50.50.60 348 421 0.04 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 153 475 5.7E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 SUPERFAMILY SSF46548 2 163 2.62E-36 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 SUPERFAMILY SSF51971 151 421 1.06E-61 T 29-03-2018 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 493 1.3E-258 T 29-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 Gene3D G3DSA:3.40.50.720 150 248 2.2E-20 T 29-03-2018 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 PRINTS PR00419 Adrenodoxin reductase family signature 295 309 7.0E-25 T 29-03-2018 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 PRINTS PR00419 Adrenodoxin reductase family signature 154 176 7.0E-25 T 29-03-2018 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 PRINTS PR00419 Adrenodoxin reductase family signature 219 229 7.0E-25 T 29-03-2018 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 PRINTS PR00419 Adrenodoxin reductase family signature 177 190 7.0E-25 T 29-03-2018 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 Gene3D G3DSA:1.10.1060.10 3 149 3.7E-41 T 29-03-2018 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 Gene3D G3DSA:3.50.50.60 442 493 2.4E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS09325 d39b2c4bd8b587bb52eee3e9b632f75b 493 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 140 2.2E-21 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CXR48_RS07355 6b8c52b1bf587c5f408529ea8e8ad869 62 Pfam PF17259 Family of unknown function (DUF5325) 1 61 7.7E-26 T 29-03-2018 IPR035211 Protein of unknown function DUF5325 CXR48_RS07355 6b8c52b1bf587c5f408529ea8e8ad869 62 ProDom PD699877 YLAF TRANSMEMBRANE MEMBRANE BH2633 1 56 5.0E-11 T 29-03-2018 IPR035211 Protein of unknown function DUF5325 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 378 393 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 Pfam PF01590 GAF domain 89 195 1.8E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 578 598 2.2E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 561 578 2.2E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 SMART SM00382 311 455 3.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 Pfam PF02954 Bacterial regulatory protein, Fis family 556 595 6.0E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 Pfam PF00158 Sigma-54 interaction domain 293 459 2.0E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 Gene3D G3DSA:1.10.8.60 465 532 1.1E-9 T 29-03-2018 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 SUPERFAMILY SSF46689 500 597 3.37E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 Gene3D G3DSA:1.10.10.60 533 599 8.0E-12 T 29-03-2018 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 Gene3D G3DSA:3.30.450.40 49 204 6.9E-5 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 Gene3D G3DSA:3.40.50.300 286 463 2.4E-28 T 29-03-2018 CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 SUPERFAMILY SSF52540 293 521 4.61E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03985 79240f9f4bfc66cea0bb0cd61730e87e 602 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 500 509 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 265 1.3E-84 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 264 5.0E-36 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 98 7.9E-23 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 SUPERFAMILY SSF51735 2 157 4.34E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 SUPERFAMILY SSF48179 160 268 2.89E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 265 26.348 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 Gene3D G3DSA:1.10.3730.10 159 270 2.0E-38 T 29-03-2018 CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 PIRSF PIRSF000193 1 268 2.8E-80 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 221 243 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CXR48_RS11310 70ce1496bc6c6d1c2cf05d4502f9dbfc 280 Gene3D G3DSA:3.40.50.720 1 158 6.8E-28 T 29-03-2018 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 330 349 9.7E-45 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 9.7E-45 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 9.7E-45 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 9.7E-45 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 225 244 9.7E-45 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 46 66 9.7E-45 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 9.7E-45 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 9.7E-45 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 9.7E-45 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 Pfam PF00375 Sodium:dicarboxylate symporter family 8 403 1.3E-125 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 Gene3D G3DSA:1.10.3860.10 2 410 2.5E-128 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 SUPERFAMILY SSF118215 8 404 1.14E-123 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 298 321 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CXR48_RS05090 83b6591cae0f60978f55358dc11bc83c 429 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 38 53 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CXR48_RS18200 4c10d8385f1c890565c42d2b6657dc85 286 Pfam PF01501 Glycosyl transferase family 8 8 256 2.4E-60 T 29-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CXR48_RS18200 4c10d8385f1c890565c42d2b6657dc85 286 Gene3D G3DSA:3.90.550.10 7 281 5.2E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS18200 4c10d8385f1c890565c42d2b6657dc85 286 SUPERFAMILY SSF53448 7 277 2.76E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 Gene3D G3DSA:1.10.10.10 3 65 1.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 SUPERFAMILY SSF46785 6 62 1.01E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 Gene3D G3DSA:2.30.30.100 280 322 1.4E-8 T 29-03-2018 CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 Pfam PF02237 Biotin protein ligase C terminal domain 281 324 8.1E-8 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 86 324 3.1E-81 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 Pfam PF08279 HTH domain 9 60 8.0E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 Pfam PF03099 Biotin/lipoate A/B protein ligase family 91 214 2.5E-18 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 325 37.604 T 29-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 SUPERFAMILY SSF55681 72 276 1.13E-60 T 29-03-2018 CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 10 77 3.0E-26 T 29-03-2018 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 CXR48_RS10630 6c5f9fd8507c1c2b89dfe176c6d0eb33 325 Gene3D G3DSA:3.30.930.10 66 278 7.1E-67 T 29-03-2018 CXR48_RS10685 37c9437281ad162b5de735bab0fcd23b 255 PIRSF PIRSF036636 1 255 5.4E-149 T 29-03-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 CXR48_RS10685 37c9437281ad162b5de735bab0fcd23b 255 Gene3D G3DSA:1.10.760.10 178 255 1.0E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS10685 37c9437281ad162b5de735bab0fcd23b 255 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 71 158 3.0E-8 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CXR48_RS10685 37c9437281ad162b5de735bab0fcd23b 255 SUPERFAMILY SSF81648 21 156 6.02E-30 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CXR48_RS10685 37c9437281ad162b5de735bab0fcd23b 255 SUPERFAMILY SSF46626 132 251 2.33E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS10685 37c9437281ad162b5de735bab0fcd23b 255 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 181 249 1.4E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS10685 37c9437281ad162b5de735bab0fcd23b 255 Gene3D G3DSA:1.20.810.10 15 166 2.4E-26 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 SMART SM00470 31 122 5.4E-35 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 SUPERFAMILY SSF110849 23 125 2.25E-28 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 Gene3D G3DSA:1.10.10.730 123 170 3.0E-18 T 29-03-2018 CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 Hamap MF_02015 Nucleoid occlusion protein [noc]. 3 283 39.043 T 29-03-2018 IPR023705 Nucleoid occlusion protein CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 Gene3D G3DSA:3.90.1530.10 18 122 3.6E-36 T 29-03-2018 CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 Gene3D G3DSA:1.10.10.10 205 270 0.18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 Pfam PF02195 ParB-like nuclease domain 32 121 1.0E-27 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 29 283 3.1E-112 T 29-03-2018 IPR023705 Nucleoid occlusion protein CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 SUPERFAMILY SSF109709 116 221 4.71E-33 T 29-03-2018 CXR48_RS19400 907852163860ed82bbee866072ea26e9 283 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 27 208 6.2E-66 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 SUPERFAMILY SSF82693 134 180 2.3E-16 T 29-03-2018 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 SUPERFAMILY SSF82693 297 340 2.3E-16 T 29-03-2018 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 SUPERFAMILY SSF82866 319 520 4.19E-44 T 29-03-2018 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 SUPERFAMILY SSF82866 816 1040 1.83E-45 T 29-03-2018 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 Gene3D G3DSA:3.30.2090.10 727 816 1.5E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 Gene3D G3DSA:3.30.2090.10 179 295 9.8E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 Pfam PF00873 AcrB/AcrD/AcrF family 4 1034 1.1E-206 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 Gene3D G3DSA:3.30.70.1430 41 140 1.1E-24 T 29-03-2018 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 SUPERFAMILY SSF82714 184 248 6.93E-5 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 SUPERFAMILY SSF82714 731 814 8.24E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 Gene3D G3DSA:1.20.1640.10 817 1036 1.8E-40 T 29-03-2018 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 Gene3D G3DSA:1.20.1640.10 296 524 5.9E-48 T 29-03-2018 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 7.2E-45 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 469 492 7.2E-45 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 413 437 7.2E-45 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 7.2E-45 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 358 381 7.2E-45 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 494 517 7.2E-45 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 385 406 7.2E-45 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CXR48_RS03410 8c6ac5b8901b57eba9932a2f976a2fbe 1047 SUPERFAMILY SSF82693 41 132 1.53E-21 T 29-03-2018 CXR48_RS08345 8204bd6bbd87292d0e660402bb18cf06 296 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 152 293 2.4E-10 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CXR48_RS08345 8204bd6bbd87292d0e660402bb18cf06 296 SUPERFAMILY SSF51735 133 248 1.64E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08345 8204bd6bbd87292d0e660402bb18cf06 296 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 5 289 3.5E-137 T 29-03-2018 IPR014215 Dipicolinic acid synthetase subunit A CXR48_RS08345 8204bd6bbd87292d0e660402bb18cf06 296 Gene3D G3DSA:3.40.50.720 137 272 5.9E-22 T 29-03-2018 CXR48_RS08345 8204bd6bbd87292d0e660402bb18cf06 296 Gene3D G3DSA:3.40.50.720 1 136 1.9E-5 T 29-03-2018 CXR48_RS08345 8204bd6bbd87292d0e660402bb18cf06 296 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 123 6.1E-29 T 29-03-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal CXR48_RS00475 039b6533e4d7646e3b219c9987b07142 69 SUPERFAMILY SSF47413 4 66 6.97E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS00475 039b6533e4d7646e3b219c9987b07142 69 Gene3D G3DSA:1.10.260.40 1 69 2.6E-18 T 29-03-2018 CXR48_RS00475 039b6533e4d7646e3b219c9987b07142 69 SMART SM00530 9 64 1.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS00475 039b6533e4d7646e3b219c9987b07142 69 Pfam PF01381 Helix-turn-helix 10 64 7.8E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS07470 fda5e201f26ef0fa008cb0d8802a396b 149 SUPERFAMILY SSF158622 5 126 1.7E-34 T 29-03-2018 IPR023378 YheA/YmcA-like domain CXR48_RS07470 fda5e201f26ef0fa008cb0d8802a396b 149 Gene3D G3DSA:1.20.1500.10 9 118 2.1E-28 T 29-03-2018 IPR023378 YheA/YmcA-like domain CXR48_RS07470 fda5e201f26ef0fa008cb0d8802a396b 149 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 12 115 4.3E-21 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CXR48_RS00825 db79bd5df674f1cb28ec63f6b39adbfc 59 PIRSF PIRSF002211 1 59 2.7E-28 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00825 db79bd5df674f1cb28ec63f6b39adbfc 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 29-03-2018 IPR018038 Ribosomal protein L30, conserved site CXR48_RS00825 db79bd5df674f1cb28ec63f6b39adbfc 59 SUPERFAMILY SSF55129 1 58 4.84E-21 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CXR48_RS00825 db79bd5df674f1cb28ec63f6b39adbfc 59 Gene3D G3DSA:3.30.1390.20 4 58 2.0E-24 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CXR48_RS00825 db79bd5df674f1cb28ec63f6b39adbfc 59 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 3.0E-20 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CXR48_RS00825 db79bd5df674f1cb28ec63f6b39adbfc 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.58 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00825 db79bd5df674f1cb28ec63f6b39adbfc 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 7.7E-26 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS11680 28398ad5cf08570df6131f6d517ad02d 130 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 129 24.964 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CXR48_RS11680 28398ad5cf08570df6131f6d517ad02d 130 Pfam PF01029 NusB family 4 124 2.5E-42 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CXR48_RS11680 28398ad5cf08570df6131f6d517ad02d 130 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 127 1.3E-45 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CXR48_RS11680 28398ad5cf08570df6131f6d517ad02d 130 Gene3D G3DSA:1.10.940.10 1 130 5.5E-48 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CXR48_RS11680 28398ad5cf08570df6131f6d517ad02d 130 SUPERFAMILY SSF48013 2 125 1.96E-43 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 Pfam PF00375 Sodium:dicarboxylate symporter family 6 395 1.8E-115 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 290 313 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 Gene3D G3DSA:1.10.3860.10 1 402 6.3E-108 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 PRINTS PR00173 Glutamate-aspartate symporter signature 349 369 1.6E-34 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 PRINTS PR00173 Glutamate-aspartate symporter signature 70 95 1.6E-34 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 PRINTS PR00173 Glutamate-aspartate symporter signature 322 341 1.6E-34 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 PRINTS PR00173 Glutamate-aspartate symporter signature 3 23 1.6E-34 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 PRINTS PR00173 Glutamate-aspartate symporter signature 187 206 1.6E-34 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 PRINTS PR00173 Glutamate-aspartate symporter signature 140 162 1.6E-34 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 PRINTS PR00173 Glutamate-aspartate symporter signature 287 313 1.6E-34 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 PRINTS PR00173 Glutamate-aspartate symporter signature 222 241 1.6E-34 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 SUPERFAMILY SSF118215 6 396 1.57E-109 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS01335 cbe4a253a8023c5233478be37a647ada 416 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 32 47 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CXR48_RS04735 d3f25295ad64d2fe5c8d893dc874952e 163 Pfam PF08281 Sigma-70, region 4 105 152 4.6E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS04735 d3f25295ad64d2fe5c8d893dc874952e 163 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 28 58 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS04735 d3f25295ad64d2fe5c8d893dc874952e 163 Gene3D G3DSA:1.10.10.10 85 159 1.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04735 d3f25295ad64d2fe5c8d893dc874952e 163 Pfam PF04542 Sigma-70 region 2 6 72 4.7E-19 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS04735 d3f25295ad64d2fe5c8d893dc874952e 163 SUPERFAMILY SSF88946 4 81 4.19E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS04735 d3f25295ad64d2fe5c8d893dc874952e 163 Gene3D G3DSA:1.10.1740.10 2 74 3.1E-20 T 29-03-2018 CXR48_RS04735 d3f25295ad64d2fe5c8d893dc874952e 163 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 2 156 2.3E-70 T 29-03-2018 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS04735 d3f25295ad64d2fe5c8d893dc874952e 163 SUPERFAMILY SSF88659 93 156 7.1E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS04735 d3f25295ad64d2fe5c8d893dc874952e 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 153 9.0E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS17825 1abcd28fa8ca58933c2e297cd2305386 399 Gene3D G3DSA:3.40.640.10 43 279 6.3E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS17825 1abcd28fa8ca58933c2e297cd2305386 399 Gene3D G3DSA:3.90.1150.10 280 387 1.7E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS17825 1abcd28fa8ca58933c2e297cd2305386 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CXR48_RS17825 1abcd28fa8ca58933c2e297cd2305386 399 SUPERFAMILY SSF53383 5 387 4.62E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS17825 1abcd28fa8ca58933c2e297cd2305386 399 Pfam PF00155 Aminotransferase class I and II 33 382 1.7E-75 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS13310 7f2de7f553031cfd1288ac7d1b8273ce 321 PIRSF PIRSF026534 2 321 3.5E-101 T 29-03-2018 IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase GO:0046558 CXR48_RS13310 7f2de7f553031cfd1288ac7d1b8273ce 321 Gene3D G3DSA:2.115.10.20 43 321 9.5E-55 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS13310 7f2de7f553031cfd1288ac7d1b8273ce 321 SUPERFAMILY SSF75005 35 319 2.62E-68 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS13310 7f2de7f553031cfd1288ac7d1b8273ce 321 Pfam PF04616 Glycosyl hydrolases family 43 39 319 2.3E-48 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CXR48_RS07380 f361da764b926b4cf7fa0062b3dcd6b1 442 SMART SM00670 3 135 1.4E-25 T 29-03-2018 IPR002716 PIN domain CXR48_RS07380 f361da764b926b4cf7fa0062b3dcd6b1 442 Pfam PF13638 PIN domain 5 147 9.3E-34 T 29-03-2018 IPR002716 PIN domain CXR48_RS07380 f361da764b926b4cf7fa0062b3dcd6b1 442 SUPERFAMILY SSF88723 4 64 4.37E-11 T 29-03-2018 IPR029060 PIN domain-like CXR48_RS07380 f361da764b926b4cf7fa0062b3dcd6b1 442 SUPERFAMILY SSF88723 94 149 4.37E-11 T 29-03-2018 IPR029060 PIN domain-like CXR48_RS07380 f361da764b926b4cf7fa0062b3dcd6b1 442 Pfam PF02562 PhoH-like protein 233 436 1.8E-53 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CXR48_RS07380 f361da764b926b4cf7fa0062b3dcd6b1 442 SUPERFAMILY SSF52540 232 422 3.23E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07380 f361da764b926b4cf7fa0062b3dcd6b1 442 Gene3D G3DSA:3.40.50.1010 1 182 7.9E-38 T 29-03-2018 IPR029060 PIN domain-like CXR48_RS07380 f361da764b926b4cf7fa0062b3dcd6b1 442 Gene3D G3DSA:3.40.50.300 231 438 2.8E-17 T 29-03-2018 CXR48_RS11255 4b8e4e664bc5c4b74a93994521535b3d 156 PIRSF PIRSF037663 1 156 1.2E-74 T 29-03-2018 IPR017255 Acetyltransferase, GNAT, predicted CXR48_RS11255 4b8e4e664bc5c4b74a93994521535b3d 156 Pfam PF00583 Acetyltransferase (GNAT) family 33 124 2.8E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS11255 4b8e4e664bc5c4b74a93994521535b3d 156 Gene3D G3DSA:3.40.630.30 1 156 2.4E-25 T 29-03-2018 CXR48_RS11255 4b8e4e664bc5c4b74a93994521535b3d 156 SUPERFAMILY SSF55729 1 155 1.86E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 Gene3D G3DSA:3.40.30.10 102 196 1.6E-7 T 29-03-2018 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 481 6.3E-38 T 29-03-2018 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 6.3E-38 T 29-03-2018 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 6.3E-38 T 29-03-2018 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 6.3E-38 T 29-03-2018 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 6.3E-38 T 29-03-2018 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 Gene3D G3DSA:3.40.30.10 2 93 2.0E-24 T 29-03-2018 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 SUPERFAMILY SSF52833 104 194 8.85E-24 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 SUPERFAMILY SSF52833 3 100 3.58E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 509 5.7E-244 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 Gene3D G3DSA:3.40.50.720 204 330 5.9E-20 T 29-03-2018 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 Gene3D G3DSA:3.50.50.60 331 435 4.3E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 Pfam PF13192 Thioredoxin domain 125 192 1.1E-8 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 SUPERFAMILY SSF51905 199 505 1.3E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 4.2E-66 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 4.2E-66 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 4.2E-66 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 4.2E-66 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 469 487 4.2E-66 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 4.2E-66 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 4.2E-66 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 4.2E-66 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 4.2E-66 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 483 2.9E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 Gene3D G3DSA:3.50.50.60 436 509 6.4E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS18825 8b19bd879e8f8ba3caf62ba8db6014d3 509 PIRSF PIRSF000238 2 509 1.2E-259 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CXR48_RS17420 b9ca53987afdee2bd0ded33ce75c7a16 170 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 20 166 9.2E-50 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CXR48_RS17420 b9ca53987afdee2bd0ded33ce75c7a16 170 Hamap MF_01398 ATP synthase subunit b [atpF]. 10 148 13.488 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CXR48_RS17420 b9ca53987afdee2bd0ded33ce75c7a16 170 Pfam PF00430 ATP synthase B/B' CF(0) 17 147 2.7E-37 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CXR48_RS17420 b9ca53987afdee2bd0ded33ce75c7a16 170 Gene3D G3DSA:1.20.5.620 53 132 1.9E-5 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CXR48_RS17420 b9ca53987afdee2bd0ded33ce75c7a16 170 SUPERFAMILY SSF81573 74 131 5.36E-10 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CXR48_RS18700 7381baff629e6ec53d1d42213341f87e 344 SUPERFAMILY SSF51735 3 154 3.64E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS18700 7381baff629e6ec53d1d42213341f87e 344 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 125 8.3E-30 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CXR48_RS18700 7381baff629e6ec53d1d42213341f87e 344 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 1 337 51.695 T 29-03-2018 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 CXR48_RS18700 7381baff629e6ec53d1d42213341f87e 344 Gene3D G3DSA:3.40.50.720 1 136 3.0E-34 T 29-03-2018 CXR48_RS18700 7381baff629e6ec53d1d42213341f87e 344 Gene3D G3DSA:3.30.360.10 137 328 1.4E-27 T 29-03-2018 CXR48_RS18700 7381baff629e6ec53d1d42213341f87e 344 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 239 2.6E-14 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CXR48_RS18700 7381baff629e6ec53d1d42213341f87e 344 SUPERFAMILY SSF55347 132 284 3.14E-16 T 29-03-2018 CXR48_RS05860 8c277be33972fc2454ea19cd19040017 373 SUPERFAMILY SSF53383 20 365 4.03E-102 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS05860 8c277be33972fc2454ea19cd19040017 373 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 363 2.8E-133 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CXR48_RS05860 8c277be33972fc2454ea19cd19040017 373 Gene3D G3DSA:3.40.640.10 3 247 4.1E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS05860 8c277be33972fc2454ea19cd19040017 373 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CXR48_RS05860 8c277be33972fc2454ea19cd19040017 373 Gene3D G3DSA:3.90.1150.10 279 372 2.8E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS05860 8c277be33972fc2454ea19cd19040017 373 Gene3D G3DSA:3.90.1150.10 249 278 3.2E-7 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS05860 8c277be33972fc2454ea19cd19040017 373 PIRSF PIRSF001434 1 366 5.5E-120 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CXR48_RS17920 ef065650150ccbeaaa667f089dcd48f3 373 Pfam PF08666 SAF domain 309 364 1.5E-6 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CXR48_RS17920 ef065650150ccbeaaa667f089dcd48f3 373 SUPERFAMILY SSF51569 4 281 2.72E-84 T 29-03-2018 CXR48_RS17920 ef065650150ccbeaaa667f089dcd48f3 373 Gene3D G3DSA:3.20.20.70 3 276 1.1E-81 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS17920 ef065650150ccbeaaa667f089dcd48f3 373 Pfam PF03102 NeuB family 37 274 3.1E-76 T 29-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 CXR48_RS17920 ef065650150ccbeaaa667f089dcd48f3 373 SMART SM00858 303 365 3.4E-6 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CXR48_RS17920 ef065650150ccbeaaa667f089dcd48f3 373 SUPERFAMILY SSF51269 299 364 2.67E-17 T 29-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 CXR48_RS17920 ef065650150ccbeaaa667f089dcd48f3 373 Gene3D G3DSA:3.90.1210.10 305 364 1.7E-19 T 29-03-2018 CXR48_RS04885 2c5bd34666a7f9632eea29ca6c842a24 500 Pfam PF04055 Radical SAM superfamily 179 351 1.9E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS04885 2c5bd34666a7f9632eea29ca6c842a24 500 Gene3D G3DSA:3.20.20.70 117 498 3.8E-40 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS04885 2c5bd34666a7f9632eea29ca6c842a24 500 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 88 490 4.0E-150 T 29-03-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ CXR48_RS04885 2c5bd34666a7f9632eea29ca6c842a24 500 SMART SM00729 171 395 5.2E-47 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CXR48_RS04885 2c5bd34666a7f9632eea29ca6c842a24 500 SUPERFAMILY SSF102114 155 482 5.23E-70 T 29-03-2018 CXR48_RS12585 761eebfcd27f7f3244b6a9350b8fe770 309 Pfam PF01136 Peptidase family U32 75 306 9.0E-68 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CXR48_RS12585 761eebfcd27f7f3244b6a9350b8fe770 309 Gene3D G3DSA:3.20.20.70 4 271 5.4E-5 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 Gene3D G3DSA:1.20.5.100 199 221 5.0E-15 T 29-03-2018 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 SUPERFAMILY SSF48179 197 295 3.06E-32 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 182 6.1E-70 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 SUPERFAMILY SSF52413 299 425 6.41E-32 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 411 5.6E-142 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 SUPERFAMILY SSF51735 1 188 4.89E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 PIRSF PIRSF500134 1 433 1.4E-178 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 Gene3D G3DSA:3.40.50.720 222 427 8.3E-73 T 29-03-2018 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 SMART SM00984 313 415 6.3E-39 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 Gene3D G3DSA:3.40.50.720 1 195 1.3E-58 T 29-03-2018 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 290 8.8E-39 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 313 412 4.5E-27 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS17125 a96a415bf152e57e836b8af5ae20b366 441 PIRSF PIRSF000124 1 430 1.3E-143 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CXR48_RS12225 2e24ef50e0456605deffda1400b50051 311 SUPERFAMILY SSF53335 95 310 2.81E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS12225 2e24ef50e0456605deffda1400b50051 311 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 311 2.9E-109 T 29-03-2018 CXR48_RS12225 2e24ef50e0456605deffda1400b50051 311 Gene3D G3DSA:3.40.50.150 116 311 1.2E-46 T 29-03-2018 CXR48_RS12225 2e24ef50e0456605deffda1400b50051 311 PIRSF PIRSF000401 1 311 3.2E-110 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CXR48_RS12225 2e24ef50e0456605deffda1400b50051 311 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 36.404 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CXR48_RS12225 2e24ef50e0456605deffda1400b50051 311 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 1.9E-119 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 SUPERFAMILY SSF103473 239 456 1.57E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 SUPERFAMILY SSF103473 7 193 1.57E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 Pfam PF07690 Major Facilitator Superfamily 20 396 3.7E-41 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 Gene3D G3DSA:1.20.1250.20 3 195 4.3E-30 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 Gene3D G3DSA:1.20.1250.20 243 458 9.2E-18 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 224 242 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 294 318 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 165 189 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 349 369 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 203 221 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 329 349 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 258 283 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 391 410 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 78 100 1.2E-164 T 29-03-2018 CXR48_RS12415 6bd24956a6a89025a0168f81525e65ab 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 1.2E-164 T 29-03-2018 CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 Gene3D G3DSA:3.40.190.10 168 257 5.9E-15 T 29-03-2018 CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 Gene3D G3DSA:3.40.190.10 88 167 3.5E-16 T 29-03-2018 CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 SUPERFAMILY SSF53850 87 285 3.38E-38 T 29-03-2018 CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 Gene3D G3DSA:1.10.10.10 1 86 1.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 SUPERFAMILY SSF46785 2 109 1.33E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 8.8E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS09315 f4f49a1ca698dba05d2db786256c3aa1 288 Pfam PF03466 LysR substrate binding domain 86 281 2.1E-42 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS12325 8f801dc79917b8cf1716fd62b8b9f447 189 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 188 32.771 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CXR48_RS12325 8f801dc79917b8cf1716fd62b8b9f447 189 Pfam PF01467 Cytidylyltransferase-like 6 162 1.7E-36 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CXR48_RS12325 8f801dc79917b8cf1716fd62b8b9f447 189 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 187 5.6E-60 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CXR48_RS12325 8f801dc79917b8cf1716fd62b8b9f447 189 Gene3D G3DSA:3.40.50.620 1 189 2.6E-53 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS12325 8f801dc79917b8cf1716fd62b8b9f447 189 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 66 1.3E-14 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CXR48_RS12325 8f801dc79917b8cf1716fd62b8b9f447 189 SUPERFAMILY SSF52374 1 187 7.82E-56 T 29-03-2018 CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 SMART SM00564 178 213 1.9E-4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 SMART SM00564 96 127 0.0081 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 SMART SM00564 303 334 8.8E-5 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 SMART SM00564 343 374 1.5E-8 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 SMART SM00564 222 254 1.1E-6 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 SMART SM00564 263 294 2.1E-8 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 SMART SM00564 137 169 8.4E-4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 Gene3D G3DSA:2.140.10.10 201 333 1.2E-30 T 29-03-2018 CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 Pfam PF13360 PQQ-like domain 75 189 9.6E-9 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 Pfam PF13360 PQQ-like domain 286 402 2.5E-13 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 Gene3D G3DSA:2.140.10.10 22 200 5.0E-21 T 29-03-2018 CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 Gene3D G3DSA:2.140.10.10 334 405 7.2E-16 T 29-03-2018 CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 SUPERFAMILY SSF50998 76 213 6.59E-16 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 SUPERFAMILY SSF50998 182 397 6.02E-30 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 Pfam PF13570 PQQ-like domain 247 283 4.3E-6 T 29-03-2018 IPR025666 Pyrrolo-quinoline quinone-like domain CXR48_RS18790 610e0984cbcae7160ed4a28b576cb148 406 Pfam PF13570 PQQ-like domain 207 245 2.2E-5 T 29-03-2018 IPR025666 Pyrrolo-quinoline quinone-like domain CXR48_RS05415 d3c46b072a51a6ee62771a9a2e649442 282 Pfam PF13509 S1 domain 4 62 3.1E-21 T 29-03-2018 CXR48_RS05415 d3c46b072a51a6ee62771a9a2e649442 282 Gene3D G3DSA:2.40.50.140 148 219 3.7E-9 T 29-03-2018 CXR48_RS05415 d3c46b072a51a6ee62771a9a2e649442 282 Gene3D G3DSA:1.10.10.10 221 279 1.4E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05415 d3c46b072a51a6ee62771a9a2e649442 282 SMART SM00316 149 211 3.7E-4 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS05415 d3c46b072a51a6ee62771a9a2e649442 282 SMART SM00316 2 62 1.6 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS05415 d3c46b072a51a6ee62771a9a2e649442 282 Gene3D G3DSA:2.40.50.140 73 128 0.0015 T 29-03-2018 CXR48_RS05415 d3c46b072a51a6ee62771a9a2e649442 282 PIRSF PIRSF012524 1 282 1.4E-116 T 29-03-2018 IPR014464 Conserved virulence factor B CXR48_RS05415 d3c46b072a51a6ee62771a9a2e649442 282 Gene3D G3DSA:2.40.50.140 1 56 0.35 T 29-03-2018 CXR48_RS12345 01798079dde4bbb4f9f4a9e868ea4663 172 Pfam PF13242 HAD-hyrolase-like 92 137 1.8E-10 T 29-03-2018 CXR48_RS12345 01798079dde4bbb4f9f4a9e868ea4663 172 Gene3D G3DSA:3.40.50.1000 38 167 1.2E-21 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12345 01798079dde4bbb4f9f4a9e868ea4663 172 Pfam PF08282 haloacid dehalogenase-like hydrolase 31 86 1.1E-5 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12345 01798079dde4bbb4f9f4a9e868ea4663 172 Gene3D G3DSA:3.40.50.1000 12 37 0.12 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12345 01798079dde4bbb4f9f4a9e868ea4663 172 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 4 169 1.6E-66 T 29-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CXR48_RS12345 01798079dde4bbb4f9f4a9e868ea4663 172 SUPERFAMILY SSF56784 16 151 1.09E-24 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12345 01798079dde4bbb4f9f4a9e868ea4663 172 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 29 139 1.8E-24 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CXR48_RS12345 01798079dde4bbb4f9f4a9e868ea4663 172 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 61 129 2.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS07415 cc8603291f640c4ba2083a5b431cded5 305 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 23 301 3.0E-97 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CXR48_RS07415 cc8603291f640c4ba2083a5b431cded5 305 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 81 103 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site CXR48_RS07415 cc8603291f640c4ba2083a5b431cded5 305 Pfam PF01040 UbiA prenyltransferase family 38 288 4.4E-57 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CXR48_RS07415 cc8603291f640c4ba2083a5b431cded5 305 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 21 304 18.286 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CXR48_RS00295 ef150d09f908cb5d063380f15b287ee7 289 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 279 35.644 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CXR48_RS00295 ef150d09f908cb5d063380f15b287ee7 289 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 1 287 3.8E-120 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CXR48_RS00295 ef150d09f908cb5d063380f15b287ee7 289 Pfam PF00288 GHMP kinases N terminal domain 87 144 1.5E-12 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CXR48_RS00295 ef150d09f908cb5d063380f15b287ee7 289 SUPERFAMILY SSF55060 161 281 1.12E-31 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CXR48_RS00295 ef150d09f908cb5d063380f15b287ee7 289 SUPERFAMILY SSF54211 2 157 3.57E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS00295 ef150d09f908cb5d063380f15b287ee7 289 Gene3D G3DSA:3.30.70.890 161 287 8.2E-29 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CXR48_RS00295 ef150d09f908cb5d063380f15b287ee7 289 PIRSF PIRSF010376 1 288 2.9E-99 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CXR48_RS00295 ef150d09f908cb5d063380f15b287ee7 289 Pfam PF08544 GHMP kinases C terminal 197 270 9.3E-9 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CXR48_RS00295 ef150d09f908cb5d063380f15b287ee7 289 Gene3D G3DSA:3.30.230.10 4 159 1.5E-50 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 SUPERFAMILY SSF56601 301 708 8.35E-103 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 SUPERFAMILY SSF56601 244 266 8.35E-103 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 SMART SM00060 710 785 5.4E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 Pfam PF00905 Penicillin binding protein transpeptidase domain 357 645 4.6E-48 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 Gene3D G3DSA:1.10.3810.10 79 279 3.3E-79 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 SUPERFAMILY SSF49265 711 790 2.95E-9 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 Gene3D G3DSA:3.40.710.10 286 706 7.2E-93 T 29-03-2018 CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 Gene3D G3DSA:2.60.40.10 707 827 1.5E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 97 650 4.1E-175 T 29-03-2018 CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 SUPERFAMILY SSF53955 75 281 1.94E-73 T 29-03-2018 IPR023346 Lysozyme-like domain CXR48_RS10570 508852487654ca63d1a146e375d82a4e 927 Pfam PF00912 Transglycosylase 87 262 4.3E-63 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 SUPERFAMILY SSF46548 278 392 2.54E-15 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 SUPERFAMILY SSF100950 65 89 1.34E-39 T 29-03-2018 CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 SUPERFAMILY SSF100950 135 296 1.34E-39 T 29-03-2018 CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 Gene3D G3DSA:3.30.70.20 282 316 0.056 T 29-03-2018 CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 Gene3D G3DSA:3.40.50.10420 138 281 8.5E-48 T 29-03-2018 CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 Gene3D G3DSA:3.40.50.10420 65 137 5.5E-10 T 29-03-2018 CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 Pfam PF02589 LUD domain 70 295 2.1E-56 T 29-03-2018 IPR003741 LUD domain CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 455 5.2E-223 T 29-03-2018 IPR004452 4Fe-4S binding protein GO:0019516 CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 Gene3D G3DSA:1.10.1060.10 317 396 2.6E-10 T 29-03-2018 CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 475 68.519 T 29-03-2018 IPR022825 Lactate utilization protein B CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 Pfam PF13183 4Fe-4S dicluster domain 311 377 2.2E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 313 324 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CXR48_RS16100 cddf218479a3c44547e31c86e8d25860 476 Pfam PF11870 Domain of unknown function (DUF3390) 385 471 3.1E-21 T 29-03-2018 IPR024569 4Fe-4S binding protein, C-terminal CXR48_RS10170 86f9ed3b01c55f560c6e3538b595db11 102 Gene3D G3DSA:1.10.10.10 1 102 5.3E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10170 86f9ed3b01c55f560c6e3538b595db11 102 SUPERFAMILY SSF46767 3 84 2.35E-20 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS10170 86f9ed3b01c55f560c6e3538b595db11 102 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 3 83 8.6E-23 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 Gene3D G3DSA:3.30.230.10 223 395 4.1E-54 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 8 643 0.0 T 29-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 7 639 48.242 T 29-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 SMART SM00433 38 634 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 SUPERFAMILY SSF55874 9 220 3.93E-69 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 157 3.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 Pfam PF01751 Toprim domain 424 527 1.9E-17 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 Gene3D G3DSA:3.40.50.670 404 636 3.4E-95 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 Pfam PF00204 DNA gyrase B 223 393 5.8E-57 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 SMART SM00387 34 178 1.0E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 Gene3D G3DSA:3.30.565.10 21 222 1.3E-70 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 630 2.2E-30 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR00418 DNA topoisomerase II family signature 73 86 4.9E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR00418 DNA topoisomerase II family signature 509 526 4.9E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR00418 DNA topoisomerase II family signature 573 589 4.9E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR00418 DNA topoisomerase II family signature 38 53 4.9E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR00418 DNA topoisomerase II family signature 529 541 4.9E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR00418 DNA topoisomerase II family signature 269 282 4.9E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR00418 DNA topoisomerase II family signature 115 129 4.9E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR00418 DNA topoisomerase II family signature 425 439 4.9E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR00418 DNA topoisomerase II family signature 491 507 4.9E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 363 377 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 377 397 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 610 626 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 198 211 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 222 244 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 475 484 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 313 329 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 183 198 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 9 19 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 PRINTS PR01159 DNA gyrase subunit B signature 594 606 2.0E-57 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 SUPERFAMILY SSF56719 399 634 2.51E-87 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 SUPERFAMILY SSF54211 223 393 1.61E-51 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS08990 06d69d05c2590b9b957854d308cf2a31 655 ProSitePatterns PS00177 DNA topoisomerase II signature. 427 435 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS13735 de96d1207c7a5f3976af7dd2e601d350 289 Pfam PF16916 Dimerisation domain of Zinc Transporter 206 284 9.8E-22 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CXR48_RS13735 de96d1207c7a5f3976af7dd2e601d350 289 Gene3D G3DSA:3.30.70.1350 202 289 4.4E-23 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CXR48_RS13735 de96d1207c7a5f3976af7dd2e601d350 289 Gene3D G3DSA:1.20.1510.10 3 201 1.1E-48 T 29-03-2018 CXR48_RS13735 de96d1207c7a5f3976af7dd2e601d350 289 Pfam PF01545 Cation efflux family 9 201 1.1E-50 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CXR48_RS13735 de96d1207c7a5f3976af7dd2e601d350 289 SUPERFAMILY SSF161111 4 203 1.96E-57 T 29-03-2018 CXR48_RS13735 de96d1207c7a5f3976af7dd2e601d350 289 SUPERFAMILY SSF160240 206 285 1.06E-20 T 29-03-2018 CXR48_RS13735 de96d1207c7a5f3976af7dd2e601d350 289 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 5 285 7.7E-74 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CXR48_RS12915 819c27e831b1cad5538bfe7619adda6b 231 Gene3D G3DSA:1.10.150.20 50 94 3.1E-6 T 29-03-2018 CXR48_RS12915 819c27e831b1cad5538bfe7619adda6b 231 Pfam PF04002 RadC-like JAB domain 110 229 9.1E-48 T 29-03-2018 IPR025657 RadC-like JAB domain CXR48_RS12915 819c27e831b1cad5538bfe7619adda6b 231 SUPERFAMILY SSF102712 159 197 3.01E-5 T 29-03-2018 CXR48_RS12915 819c27e831b1cad5538bfe7619adda6b 231 SUPERFAMILY SSF47781 22 96 1.67E-9 T 29-03-2018 IPR010994 RuvA domain 2-like CXR48_RS12915 819c27e831b1cad5538bfe7619adda6b 231 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 180 185 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CXR48_RS12915 819c27e831b1cad5538bfe7619adda6b 231 Gene3D G3DSA:3.40.140.10 106 231 3.2E-52 T 29-03-2018 CXR48_RS12915 819c27e831b1cad5538bfe7619adda6b 231 TIGRFAM TIGR00608 radc: DNA repair protein RadC 18 231 1.7E-91 T 29-03-2018 IPR001405 RadC protein CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 Gene3D G3DSA:3.40.50.1220 191 342 1.0E-38 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 SUPERFAMILY SSF52518 358 557 3.22E-62 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 Gene3D G3DSA:3.40.50.970 343 531 9.6E-44 T 29-03-2018 CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 321 1.3E-35 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 SUPERFAMILY SSF52467 187 350 1.69E-46 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 SUPERFAMILY SSF52518 4 180 4.01E-44 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 Gene3D G3DSA:3.40.50.970 1 190 9.8E-43 T 29-03-2018 CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 526 4.2E-44 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CXR48_RS02230 5eef9797110438fd55080fe4f4843120 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.1E-45 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 SUPERFAMILY SSF50129 2 93 1.41E-34 T 29-03-2018 IPR011032 GroES-like CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 PRINTS PR00297 10kDa chaperonin signature 59 71 3.5E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 PRINTS PR00297 10kDa chaperonin signature 80 93 3.5E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 PRINTS PR00297 10kDa chaperonin signature 2 17 3.5E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 PRINTS PR00297 10kDa chaperonin signature 24 45 3.5E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 3.7E-36 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 Gene3D G3DSA:2.30.33.40 1 94 9.1E-40 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 27.025 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 SMART SM00883 1 93 6.3E-56 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CXR48_RS03080 7659a13e86a9ec574d293d9e4d3a32f0 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 149 161 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 SUPERFAMILY SSF56645 21 263 3.53E-73 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 SUPERFAMILY SSF47203 257 422 8.05E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 142 2.1E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 252 416 7.1E-35 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 Gene3D G3DSA:1.20.140.10 427 594 9.8E-10 T 29-03-2018 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 Gene3D G3DSA:1.20.140.10 241 426 6.6E-51 T 29-03-2018 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 Gene3D G3DSA:2.40.110.10 146 240 3.8E-33 T 29-03-2018 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 239 1.9E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CXR48_RS15340 873419bb177e41b4152a8870fad29d3d 594 Gene3D G3DSA:1.10.540.10 1 145 1.6E-31 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.8E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 Gene3D G3DSA:1.10.10.10 1 82 2.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 Gene3D G3DSA:3.40.190.10 86 174 3.6E-17 T 29-03-2018 CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 SUPERFAMILY SSF53850 86 294 6.81E-27 T 29-03-2018 CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 Pfam PF03466 LysR substrate binding domain 86 275 1.6E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 SUPERFAMILY SSF46785 2 109 5.34E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 Gene3D G3DSA:3.40.190.10 175 260 7.1E-13 T 29-03-2018 CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS15805 4dce3af55ae3294ff7b61211e3e306d7 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS02545 731ee80c4c0d469a43667ebd69060aff 467 SUPERFAMILY SSF103473 15 434 2.09E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS02545 731ee80c4c0d469a43667ebd69060aff 467 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS02545 731ee80c4c0d469a43667ebd69060aff 467 Gene3D G3DSA:1.20.1250.20 228 457 1.6E-26 T 29-03-2018 CXR48_RS02545 731ee80c4c0d469a43667ebd69060aff 467 Pfam PF07690 Major Facilitator Superfamily 27 359 4.3E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS02545 731ee80c4c0d469a43667ebd69060aff 467 Gene3D G3DSA:1.20.1250.20 16 227 2.9E-23 T 29-03-2018 CXR48_RS03900 f4d696030c9533c839f20ca0098352ef 264 Pfam PF14167 YfkD-like protein 33 264 3.8E-119 T 29-03-2018 IPR025548 YfkD-like protein CXR48_RS09570 162965f9ac439025ad3382170f63c720 248 Gene3D G3DSA:3.60.15.10 20 246 3.5E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS09570 162965f9ac439025ad3382170f63c720 248 SUPERFAMILY SSF56281 20 240 4.46E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS09570 162965f9ac439025ad3382170f63c720 248 SMART SM00849 19 224 8.1E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS09570 162965f9ac439025ad3382170f63c720 248 Pfam PF00753 Metallo-beta-lactamase superfamily 23 203 1.9E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS03180 771f2ce12e9a491bc7078fff3b43414a 122 Pfam PF03330 Lytic transglycolase 30 117 9.4E-9 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CXR48_RS03180 771f2ce12e9a491bc7078fff3b43414a 122 Gene3D G3DSA:2.40.40.10 28 122 0.0011 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CXR48_RS05375 329fda211b6adecee98728458150edfc 341 Gene3D G3DSA:1.10.260.40 3 58 1.9E-23 T 29-03-2018 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 Gene3D G3DSA:3.40.50.2300 171 335 8.6E-55 T 29-03-2018 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 SMART SM00354 2 72 3.1E-37 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 SUPERFAMILY SSF47413 2 61 4.74E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 Gene3D G3DSA:3.40.50.2300 59 170 2.3E-31 T 29-03-2018 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 Pfam PF13377 Periplasmic binding protein-like domain 172 332 7.8E-46 T 29-03-2018 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 2.1E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 2.1E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 5.4E-22 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 29-03-2018 CXR48_RS05375 329fda211b6adecee98728458150edfc 341 SUPERFAMILY SSF53822 62 336 8.58E-87 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS18575 678a46024032e3936ff15e26ed8cc5ea 148 SUPERFAMILY SSF111064 7 148 1.83E-61 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP CXR48_RS18575 678a46024032e3936ff15e26ed8cc5ea 148 Pfam PF09021 HutP 9 146 2.5E-36 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP CXR48_RS18575 678a46024032e3936ff15e26ed8cc5ea 148 Hamap MF_00779 Hut operon positive regulatory protein [hutP]. 1 148 45.151 T 29-03-2018 IPR023552 Hut operon regulatory protein HutP, bacillales CXR48_RS18575 678a46024032e3936ff15e26ed8cc5ea 148 Gene3D G3DSA:3.40.1510.10 6 148 5.3E-47 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 SUPERFAMILY SSF47831 23 143 4.84E-36 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 Gene3D G3DSA:3.50.30.10 137 254 7.5E-30 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 Gene3D G3DSA:1.10.274.10 25 136 3.2E-38 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 126 2.0E-33 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 4 566 6.6E-274 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 1.8E-32 T 29-03-2018 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 1.8E-32 T 29-03-2018 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 1.8E-32 T 29-03-2018 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 1.8E-32 T 29-03-2018 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 SUPERFAMILY SSF52009 125 246 2.09E-36 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 SUPERFAMILY SSF51621 249 547 5.76E-113 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 Pfam PF00391 PEP-utilising enzyme, mobile domain 153 225 5.8E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 Gene3D G3DSA:3.20.20.60 255 571 3.7E-103 T 29-03-2018 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 540 2.1E-129 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CXR48_RS06880 7d187685203e54ba1b547fbc6513703b 571 PIRSF PIRSF000732 1 571 1.1E-226 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CXR48_RS19215 7326b8ef184b145ec1bbbcb47b390780 150 Gene3D G3DSA:1.10.10.10 14 114 1.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19215 7326b8ef184b145ec1bbbcb47b390780 150 SUPERFAMILY SSF46785 4 143 3.21E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19215 7326b8ef184b145ec1bbbcb47b390780 150 Pfam PF01047 MarR family 28 85 4.4E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19215 7326b8ef184b145ec1bbbcb47b390780 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 3.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19215 7326b8ef184b145ec1bbbcb47b390780 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 3.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19215 7326b8ef184b145ec1bbbcb47b390780 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 3.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19215 7326b8ef184b145ec1bbbcb47b390780 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 3.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19215 7326b8ef184b145ec1bbbcb47b390780 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 60 94 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CXR48_RS19215 7326b8ef184b145ec1bbbcb47b390780 150 SMART SM00347 21 121 2.3E-25 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 Pfam PF02355 Protein export membrane protein 551 727 1.8E-66 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 Pfam PF02355 Protein export membrane protein 241 409 2.4E-15 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 420 32.747 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 447 730 24.846 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 SUPERFAMILY SSF82866 553 731 3.14E-36 T 29-03-2018 CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 SUPERFAMILY SSF82866 215 413 3.01E-42 T 29-03-2018 CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 Pfam PF07549 SecD/SecF GG Motif 469 492 2.7E-5 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 PRINTS PR01755 Bacterial translocase SecF protein signature 474 489 8.6E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 PRINTS PR01755 Bacterial translocase SecF protein signature 584 598 8.6E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 PRINTS PR01755 Bacterial translocase SecF protein signature 632 650 8.6E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 PRINTS PR01755 Bacterial translocase SecF protein signature 667 682 8.6E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 476 719 2.4E-69 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 33 405 7.1E-119 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 Gene3D G3DSA:1.20.1640.10 195 411 1.7E-35 T 29-03-2018 CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 179 398 2.9E-59 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 554 716 7.3E-51 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CXR48_RS12745 352f6058190007c559015e71f934cbe9 739 Gene3D G3DSA:1.20.1640.10 521 739 5.5E-29 T 29-03-2018 CXR48_RS07795 46c7345a0b449e507de2177b9c60c92d 568 Gene3D G3DSA:2.30.310.10 1 166 3.7E-54 T 29-03-2018 CXR48_RS07795 46c7345a0b449e507de2177b9c60c92d 568 Gene3D G3DSA:3.40.970.40 240 288 4.3E-15 T 29-03-2018 CXR48_RS07795 46c7345a0b449e507de2177b9c60c92d 568 Gene3D G3DSA:1.10.8.50 167 236 7.3E-18 T 29-03-2018 CXR48_RS07795 46c7345a0b449e507de2177b9c60c92d 568 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 2.5E-166 T 29-03-2018 CXR48_RS07795 46c7345a0b449e507de2177b9c60c92d 568 Pfam PF05670 Domain of unknown function (DUF814) 454 537 2.3E-29 T 29-03-2018 IPR008532 Domain of unknown function DUF814 CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 SUPERFAMILY SSF52518 382 568 2.06E-30 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 Gene3D G3DSA:3.40.50.970 365 571 1.4E-31 T 29-03-2018 CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 2 568 37.864 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 9 442 1.4E-158 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 Pfam PF16582 Middle domain of thiamine pyrophosphate 218 400 2.4E-17 T 29-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 430 548 8.9E-8 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 176 3.8E-35 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 SUPERFAMILY SSF52518 13 179 1.69E-32 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 Gene3D G3DSA:3.40.50.970 7 201 7.1E-52 T 29-03-2018 CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 PIRSF PIRSF004983 1 575 6.8E-207 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 SUPERFAMILY SSF52467 165 367 7.85E-10 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS14255 dc09f0298ce08298ddbb72c843f4b1f0 578 Gene3D G3DSA:3.40.50.1220 204 364 3.7E-32 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS01305 85ef417719a33e9c2e5d86b5e8ad88a0 384 Gene3D G3DSA:3.40.50.20 1 121 2.2E-18 T 29-03-2018 CXR48_RS01305 85ef417719a33e9c2e5d86b5e8ad88a0 384 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 1 384 51.561 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CXR48_RS01305 85ef417719a33e9c2e5d86b5e8ad88a0 384 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 6 383 1.2E-187 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CXR48_RS01305 85ef417719a33e9c2e5d86b5e8ad88a0 384 SUPERFAMILY SSF56059 105 307 9.9E-57 T 29-03-2018 CXR48_RS01305 85ef417719a33e9c2e5d86b5e8ad88a0 384 SUPERFAMILY SSF51246 312 383 1.43E-13 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CXR48_RS01305 85ef417719a33e9c2e5d86b5e8ad88a0 384 Pfam PF02222 ATP-grasp domain 115 286 2.9E-58 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CXR48_RS01305 85ef417719a33e9c2e5d86b5e8ad88a0 384 SUPERFAMILY SSF52440 4 104 3.6E-28 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS01305 85ef417719a33e9c2e5d86b5e8ad88a0 384 Gene3D G3DSA:3.30.1490.20 123 189 9.0E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS01305 85ef417719a33e9c2e5d86b5e8ad88a0 384 Gene3D G3DSA:3.30.470.20 190 383 1.3E-37 T 29-03-2018 CXR48_RS02700 69a29f30debc74269fc00d8ab5aa2b67 264 SMART SM01130 3 264 1.1E-28 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS02700 69a29f30debc74269fc00d8ab5aa2b67 264 PIRSF PIRSF001365 1 264 8.5E-49 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS02700 69a29f30debc74269fc00d8ab5aa2b67 264 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 2.4E-12 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS02700 69a29f30debc74269fc00d8ab5aa2b67 264 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 2.4E-12 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS02700 69a29f30debc74269fc00d8ab5aa2b67 264 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 2.4E-12 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS02700 69a29f30debc74269fc00d8ab5aa2b67 264 Pfam PF00701 Dihydrodipicolinate synthetase family 5 263 1.4E-43 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS02700 69a29f30debc74269fc00d8ab5aa2b67 264 Gene3D G3DSA:3.20.20.70 1 264 2.8E-52 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS02700 69a29f30debc74269fc00d8ab5aa2b67 264 SUPERFAMILY SSF51569 5 263 5.34E-55 T 29-03-2018 CXR48_RS13650 f39426b5c44d693d76ff5f1b7b2458a8 446 Pfam PF05525 Branched-chain amino acid transport protein 8 432 1.5E-165 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CXR48_RS13650 f39426b5c44d693d76ff5f1b7b2458a8 446 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 420 2.7E-163 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CXR48_RS14695 d76e6f663aad1d572f3664e93086ac90 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 329 5.1E-45 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CXR48_RS14695 d76e6f663aad1d572f3664e93086ac90 348 Gene3D G3DSA:1.10.3470.10 54 345 7.8E-50 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 SUPERFAMILY SSF63380 146 247 8.96E-28 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 Gene3D G3DSA:2.40.30.10 156 238 9.3E-27 T 29-03-2018 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 Pfam PF00175 Oxidoreductase NAD-binding domain 258 365 4.6E-17 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 PRINTS PR00409 Phthalate dioxygenase reductase family signature 221 235 3.1E-13 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 PRINTS PR00409 Phthalate dioxygenase reductase family signature 174 184 3.1E-13 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 PRINTS PR00409 Phthalate dioxygenase reductase family signature 257 276 3.1E-13 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 PRINTS PR00409 Phthalate dioxygenase reductase family signature 235 249 3.1E-13 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 Pfam PF00970 Oxidoreductase FAD-binding domain 152 248 3.6E-12 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 SUPERFAMILY SSF52343 251 386 2.75E-35 T 29-03-2018 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 Gene3D G3DSA:1.10.490.10 1 155 2.6E-41 T 29-03-2018 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 SUPERFAMILY SSF46458 1 149 2.49E-43 T 29-03-2018 IPR009050 Globin-like CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 Gene3D G3DSA:3.40.50.80 239 380 3.6E-28 T 29-03-2018 CXR48_RS14450 0953875f915fa8bee7a5a5bb3652cfc0 391 Pfam PF00042 Globin 8 102 7.6E-11 T 29-03-2018 IPR000971 Globin GO:0020037 CXR48_RS12595 4dc33106d73a0a9f82d1c05f32f44142 363 Gene3D G3DSA:3.30.160.60 89 119 0.0015 T 29-03-2018 CXR48_RS12595 4dc33106d73a0a9f82d1c05f32f44142 363 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 21 360 33.755 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CXR48_RS12595 4dc33106d73a0a9f82d1c05f32f44142 363 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 15 360 2.3E-133 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CXR48_RS12595 4dc33106d73a0a9f82d1c05f32f44142 363 Gene3D G3DSA:3.30.160.60 329 362 9.9E-12 T 29-03-2018 CXR48_RS12595 4dc33106d73a0a9f82d1c05f32f44142 363 Pfam PF02618 YceG-like family 55 354 9.6E-83 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.10 1511 1604 2.2E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.10 1323 1417 1.2E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.10 1418 1510 1.5E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.10 1605 1698 3.1E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Pfam PF05737 Collagen binding domain 557 677 2.0E-9 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Pfam PF05737 Collagen binding domain 411 535 7.3E-17 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Pfam PF05737 Collagen binding domain 975 1113 1.5E-13 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Pfam PF05737 Collagen binding domain 696 810 2.2E-5 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Pfam PF05737 Collagen binding domain 829 954 1.6E-14 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.1280 261 415 6.8E-29 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.810 1132 1219 1.6E-21 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.810 1220 1319 1.8E-21 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.810 1794 1922 1.8E-29 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49478 1802 1878 1.57E-7 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49401 50 185 1.57E-8 T 29-03-2018 IPR008966 Adhesion domain CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49478 1428 1495 6.28E-6 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.1280 47 204 9.2E-14 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49401 828 966 1.02E-21 T 29-03-2018 IPR008966 Adhesion domain CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49401 266 407 1.49E-25 T 29-03-2018 IPR008966 Adhesion domain CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.740 686 823 3.8E-20 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.740 825 968 3.3E-15 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.740 548 685 1.9E-12 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.740 416 547 2.1E-16 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49478 1234 1304 7.85E-6 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49401 546 689 1.89E-21 T 29-03-2018 IPR008966 Adhesion domain CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.740 969 1124 7.3E-19 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49478 1522 1585 9.81E-6 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49478 1613 1681 5.1E-7 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 Gene3D G3DSA:2.60.40.10 1699 1793 5.7E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49478 1334 1401 2.79E-6 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49478 1714 1765 1.73E-5 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49478 1143 1202 7.45E-8 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49401 410 544 1.41E-18 T 29-03-2018 IPR008966 Adhesion domain CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1932 1965 2.5E-6 T 29-03-2018 CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49401 693 815 5.22E-19 T 29-03-2018 IPR008966 Adhesion domain CXR48_RS03705 dda3cae7e2f632ad04144b44b60ed61d 1969 SUPERFAMILY SSF49401 971 1117 3.73E-21 T 29-03-2018 IPR008966 Adhesion domain CXR48_RS17580 920c045ef8dd2c6a57d3820e5aa13529 702 Pfam PF13183 4Fe-4S dicluster domain 274 383 1.1E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CXR48_RS17580 920c045ef8dd2c6a57d3820e5aa13529 702 Gene3D G3DSA:1.20.950.20 4 236 1.1E-46 T 29-03-2018 CXR48_RS17580 920c045ef8dd2c6a57d3820e5aa13529 702 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 371 382 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CXR48_RS17580 920c045ef8dd2c6a57d3820e5aa13529 702 SUPERFAMILY SSF103501 6 238 1.7E-18 T 29-03-2018 IPR023234 NarG-like domain CXR48_RS17580 920c045ef8dd2c6a57d3820e5aa13529 702 Gene3D G3DSA:1.10.1060.10 244 404 1.0E-32 T 29-03-2018 CXR48_RS17580 920c045ef8dd2c6a57d3820e5aa13529 702 Pfam PF02754 Cysteine-rich domain 580 667 1.0E-16 T 29-03-2018 IPR004017 Cysteine-rich domain CXR48_RS17580 920c045ef8dd2c6a57d3820e5aa13529 702 Pfam PF02754 Cysteine-rich domain 458 541 1.0E-5 T 29-03-2018 IPR004017 Cysteine-rich domain CXR48_RS17580 920c045ef8dd2c6a57d3820e5aa13529 702 SUPERFAMILY SSF46548 252 313 4.19E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CXR48_RS17580 920c045ef8dd2c6a57d3820e5aa13529 702 SUPERFAMILY SSF46548 353 399 4.19E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 ProSitePatterns PS01228 Hypothetical cof family signature 1. 12 23 - T 29-03-2018 CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 12 217 3.2E-30 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 SUPERFAMILY SSF56784 9 248 4.65E-69 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 13 244 3.4E-33 T 29-03-2018 CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 Gene3D G3DSA:3.40.50.1000 2 249 1.3E-47 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 ProSitePatterns PS01229 Hypothetical cof family signature 2. 198 220 - T 29-03-2018 CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 221 233 2.2E-5 T 29-03-2018 CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 14 28 2.2E-5 T 29-03-2018 CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 198 217 2.2E-5 T 29-03-2018 CXR48_RS02085 222e714c726aa51e984fe216a9078678 249 Pfam PF08282 haloacid dehalogenase-like hydrolase 126 244 5.5E-32 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS16605 e0696288cef37e6c79a0addc3c2660c0 113 PIRSF PIRSF000025 1 113 2.6E-38 T 29-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 CXR48_RS16605 e0696288cef37e6c79a0addc3c2660c0 113 Gene3D G3DSA:1.10.760.10 19 113 7.2E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS16605 e0696288cef37e6c79a0addc3c2660c0 113 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 41 109 4.9E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS16605 e0696288cef37e6c79a0addc3c2660c0 113 SUPERFAMILY SSF46626 1 111 1.2E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS07990 5c972be4bb835208f46f89ba66b146f2 243 Gene3D G3DSA:1.10.1270.20 170 243 3.8E-34 T 29-03-2018 CXR48_RS07990 5c972be4bb835208f46f89ba66b146f2 243 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 243 114.051 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CXR48_RS07990 5c972be4bb835208f46f89ba66b146f2 243 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 4.6E-77 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CXR48_RS07990 5c972be4bb835208f46f89ba66b146f2 243 PIRSF PIRSF000386 1 242 1.8E-103 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CXR48_RS07990 5c972be4bb835208f46f89ba66b146f2 243 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 235 1.2E-108 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CXR48_RS07990 5c972be4bb835208f46f89ba66b146f2 243 SUPERFAMILY SSF75217 1 242 9.81E-103 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CXR48_RS07990 5c972be4bb835208f46f89ba66b146f2 243 Gene3D G3DSA:3.40.1280.10 1 169 1.5E-77 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CXR48_RS15025 0c0d3408057d2b00aa9c93bac2808dcc 284 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CXR48_RS15025 0c0d3408057d2b00aa9c93bac2808dcc 284 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 283 5.3E-100 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CXR48_RS15025 0c0d3408057d2b00aa9c93bac2808dcc 284 Gene3D G3DSA:3.10.310.10 131 271 2.3E-46 T 29-03-2018 CXR48_RS15025 0c0d3408057d2b00aa9c93bac2808dcc 284 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 284 37.775 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CXR48_RS15025 0c0d3408057d2b00aa9c93bac2808dcc 284 SUPERFAMILY SSF54506 3 280 8.98E-51 T 29-03-2018 CXR48_RS15025 0c0d3408057d2b00aa9c93bac2808dcc 284 Pfam PF01678 Diaminopimelate epimerase 161 276 1.9E-33 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CXR48_RS15025 0c0d3408057d2b00aa9c93bac2808dcc 284 Pfam PF01678 Diaminopimelate epimerase 6 130 1.6E-33 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CXR48_RS15025 0c0d3408057d2b00aa9c93bac2808dcc 284 Gene3D G3DSA:3.10.310.10 1 130 7.3E-45 T 29-03-2018 CXR48_RS07430 26447be0aea6d2027eaa6cd48b4f68d4 207 Gene3D G3DSA:1.20.120.80 21 206 8.9E-49 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07430 26447be0aea6d2027eaa6cd48b4f68d4 207 Pfam PF00510 Cytochrome c oxidase subunit III 28 204 7.9E-19 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07430 26447be0aea6d2027eaa6cd48b4f68d4 207 SUPERFAMILY SSF81452 19 204 5.76E-55 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS17230 9888cf8bddc1fcd5a0d989e7a6c20ef1 398 Gene3D G3DSA:1.20.1250.20 5 195 1.5E-32 T 29-03-2018 CXR48_RS17230 9888cf8bddc1fcd5a0d989e7a6c20ef1 398 SUPERFAMILY SSF103473 10 386 3.66E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS17230 9888cf8bddc1fcd5a0d989e7a6c20ef1 398 Gene3D G3DSA:1.20.1250.20 199 392 4.1E-22 T 29-03-2018 CXR48_RS17230 9888cf8bddc1fcd5a0d989e7a6c20ef1 398 Pfam PF07690 Major Facilitator Superfamily 245 383 1.6E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS17230 9888cf8bddc1fcd5a0d989e7a6c20ef1 398 Pfam PF07690 Major Facilitator Superfamily 16 239 2.9E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS17440 5793741988501f97fb4058ef497267d9 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 7.3E-76 T 29-03-2018 CXR48_RS17440 5793741988501f97fb4058ef497267d9 209 Gene3D G3DSA:3.40.50.2020 2 207 1.5E-65 T 29-03-2018 CXR48_RS17440 5793741988501f97fb4058ef497267d9 209 SUPERFAMILY SSF53271 4 207 9.31E-72 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS17440 5793741988501f97fb4058ef497267d9 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 7.5E-93 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CXR48_RS17440 5793741988501f97fb4058ef497267d9 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.988 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CXR48_RS11005 89a60f0aab6eca08d0bea8259ee51777 197 Gene3D G3DSA:1.10.10.10 87 177 6.6E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11005 89a60f0aab6eca08d0bea8259ee51777 197 Pfam PF04079 Segregation and condensation complex subunit ScpB 10 169 1.6E-52 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CXR48_RS11005 89a60f0aab6eca08d0bea8259ee51777 197 PIRSF PIRSF019345 4 195 1.1E-55 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CXR48_RS11005 89a60f0aab6eca08d0bea8259ee51777 197 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 195 8.7E-75 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CXR48_RS11005 89a60f0aab6eca08d0bea8259ee51777 197 Gene3D G3DSA:1.10.10.10 3 86 9.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11005 89a60f0aab6eca08d0bea8259ee51777 197 SUPERFAMILY SSF46785 87 160 1.34E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11005 89a60f0aab6eca08d0bea8259ee51777 197 SUPERFAMILY SSF46785 3 83 2.99E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11005 89a60f0aab6eca08d0bea8259ee51777 197 Hamap MF_01804 Segregation and condensation protein B [scpB]. 6 185 34.341 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CXR48_RS07750 70f340ff392a79cded5f3db94d73f88a 216 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 216 30.328 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07750 70f340ff392a79cded5f3db94d73f88a 216 Gene3D G3DSA:3.40.50.2020 3 216 3.1E-40 T 29-03-2018 CXR48_RS07750 70f340ff392a79cded5f3db94d73f88a 216 SUPERFAMILY SSF53271 13 210 1.7E-53 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS07750 70f340ff392a79cded5f3db94d73f88a 216 Pfam PF00156 Phosphoribosyl transferase domain 50 163 1.8E-18 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CXR48_RS07750 70f340ff392a79cded5f3db94d73f88a 216 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 183 2.7E-53 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07905 53d5208eef599ba60a6c3dbd5f767984 300 Gene3D G3DSA:1.10.4100.10 76 275 2.4E-30 T 29-03-2018 CXR48_RS07905 53d5208eef599ba60a6c3dbd5f767984 300 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 300 8.7E-164 T 29-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CXR48_RS07905 53d5208eef599ba60a6c3dbd5f767984 300 Pfam PF03313 Serine dehydratase alpha chain 14 274 6.1E-78 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CXR48_RS05195 f9cdde51f96b3272962aae5ab98215a9 123 Pfam PF08818 Domain of unknown function (DU1801) 19 110 4.9E-11 T 29-03-2018 IPR014922 Domain of unknown function DUF1801 CXR48_RS05195 f9cdde51f96b3272962aae5ab98215a9 123 SUPERFAMILY SSF159888 1 123 6.28E-39 T 29-03-2018 CXR48_RS17355 38a38f7a8bd851bf968f621c8ff7b9aa 262 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 23 261 3.3E-91 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CXR48_RS17355 38a38f7a8bd851bf968f621c8ff7b9aa 262 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 3 261 32.137 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CXR48_RS17355 38a38f7a8bd851bf968f621c8ff7b9aa 262 Pfam PF02634 FdhD/NarQ family 27 260 6.3E-80 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CXR48_RS17355 38a38f7a8bd851bf968f621c8ff7b9aa 262 PIRSF PIRSF015626 1 262 1.7E-79 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CXR48_RS17355 38a38f7a8bd851bf968f621c8ff7b9aa 262 Gene3D G3DSA:3.10.20.10 29 84 2.3E-17 T 29-03-2018 CXR48_RS17355 38a38f7a8bd851bf968f621c8ff7b9aa 262 Gene3D G3DSA:3.40.140.10 126 262 2.2E-51 T 29-03-2018 CXR48_RS17355 38a38f7a8bd851bf968f621c8ff7b9aa 262 SUPERFAMILY SSF53927 7 260 1.44E-78 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CXR48_RS16625 1eac9eb6bf23ee9f91964e95f6466ef7 188 SUPERFAMILY SSF69754 2 110 2.62E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CXR48_RS16625 1eac9eb6bf23ee9f91964e95f6466ef7 188 Gene3D G3DSA:3.30.160.100 1 102 6.2E-29 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CXR48_RS16625 1eac9eb6bf23ee9f91964e95f6466ef7 188 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 4.5E-37 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CXR48_RS16625 1eac9eb6bf23ee9f91964e95f6466ef7 188 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 128 183 7.1E-30 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CXR48_RS16625 1eac9eb6bf23ee9f91964e95f6466ef7 188 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 187 25.121 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CXR48_RS16625 1eac9eb6bf23ee9f91964e95f6466ef7 188 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 95 8.2E-29 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CXR48_RS07495 a1145950781bf3e0440a43ad1b709788 408 Pfam PF07670 Nucleoside recognition 44 141 7.7E-7 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CXR48_RS07495 a1145950781bf3e0440a43ad1b709788 408 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 10 390 6.0E-135 T 29-03-2018 IPR014226 Sporulation integral membrane protein YlbJ CXR48_RS11160 317333c8aa330f4dd4bbe17247336a92 149 Gene3D G3DSA:1.10.10.10 8 97 3.5E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11160 317333c8aa330f4dd4bbe17247336a92 149 SUPERFAMILY SSF46785 7 141 2.27E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11160 317333c8aa330f4dd4bbe17247336a92 149 Pfam PF01475 Ferric uptake regulator family 15 136 3.1E-40 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CXR48_RS03420 2ce5bff540b26181e08c2e3389817896 458 SUPERFAMILY SSF53335 72 455 3.4E-96 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS03420 2ce5bff540b26181e08c2e3389817896 458 SUPERFAMILY SSF50249 2 64 3.26E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS03420 2ce5bff540b26181e08c2e3389817896 458 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 388 419 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site CXR48_RS03420 2ce5bff540b26181e08c2e3389817896 458 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 440 450 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CXR48_RS03420 2ce5bff540b26181e08c2e3389817896 458 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 281 452 6.6E-20 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CXR48_RS03420 2ce5bff540b26181e08c2e3389817896 458 Gene3D G3DSA:3.40.50.150 79 456 1.1E-65 T 29-03-2018 CXR48_RS03420 2ce5bff540b26181e08c2e3389817896 458 Gene3D G3DSA:2.40.50.140 1 78 8.0E-26 T 29-03-2018 CXR48_RS03420 2ce5bff540b26181e08c2e3389817896 458 Pfam PF01938 TRAM domain 10 63 1.6E-12 T 29-03-2018 IPR002792 TRAM domain CXR48_RS03420 2ce5bff540b26181e08c2e3389817896 458 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 450 1.3E-213 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CXR48_RS12850 ea5b28ac81341bf28bcb1f8a4677cfc3 147 Pfam PF01842 ACT domain 70 133 1.5E-8 T 29-03-2018 IPR002912 ACT domain CXR48_RS12850 ea5b28ac81341bf28bcb1f8a4677cfc3 147 Hamap MF_00707 UPF0735 ACT domain-containing protein . 2 146 31.946 T 29-03-2018 IPR008310 UPF0735 ACT domain-containing protein CXR48_RS12850 ea5b28ac81341bf28bcb1f8a4677cfc3 147 SUPERFAMILY SSF55021 70 143 1.5E-10 T 29-03-2018 CXR48_RS12850 ea5b28ac81341bf28bcb1f8a4677cfc3 147 PIRSF PIRSF025624 1 146 7.2E-63 T 29-03-2018 IPR008310 UPF0735 ACT domain-containing protein CXR48_RS12850 ea5b28ac81341bf28bcb1f8a4677cfc3 147 Gene3D G3DSA:3.30.70.260 64 146 1.4E-11 T 29-03-2018 CXR48_RS11515 2bf0a5e01e6dbc5aa73589d1cf7e8b17 327 Pfam PF02780 Transketolase, C-terminal domain 194 316 3.9E-42 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CXR48_RS11515 2bf0a5e01e6dbc5aa73589d1cf7e8b17 327 Gene3D G3DSA:3.40.50.920 195 326 4.3E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS11515 2bf0a5e01e6dbc5aa73589d1cf7e8b17 327 Gene3D G3DSA:3.40.50.970 1 194 6.1E-74 T 29-03-2018 CXR48_RS11515 2bf0a5e01e6dbc5aa73589d1cf7e8b17 327 SMART SM00861 4 179 6.0E-71 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS11515 2bf0a5e01e6dbc5aa73589d1cf7e8b17 327 SUPERFAMILY SSF52922 188 325 9.68E-41 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS11515 2bf0a5e01e6dbc5aa73589d1cf7e8b17 327 SUPERFAMILY SSF52518 1 204 1.77E-73 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS11515 2bf0a5e01e6dbc5aa73589d1cf7e8b17 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 3.5E-51 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Gene3D G3DSA:3.30.1360.40 237 333 2.9E-40 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 SUPERFAMILY SSF101904 500 817 1.7E-114 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 807 0.0 T 29-03-2018 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Gene3D G3DSA:1.10.268.10 345 487 3.0E-54 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 2.8E-162 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 604 7.0E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 705 2.2E-14 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 806 8.8E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 710 754 4.1E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 611 655 1.4E-7 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 506 551 4.8E-15 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Gene3D G3DSA:2.120.10.90 500 819 4.8E-127 T 29-03-2018 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 808 25.193 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 Gene3D G3DSA:3.90.199.10 35 215 4.0E-85 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 SMART SM00434 12 465 3.8E-295 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CXR48_RS00035 1fe11aa69035b733480912cac5b3c5af 819 SUPERFAMILY SSF56719 31 488 6.02E-183 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CXR48_RS04990 f81f45a815e0bd1cd9a52222949a7432 118 Pfam PF12732 YtxH-like protein 8 92 4.2E-12 T 29-03-2018 IPR024623 Uncharacterised protein family YtxH CXR48_RS04990 f81f45a815e0bd1cd9a52222949a7432 118 Gene3D G3DSA:1.20.5.50 20 118 1.1E-7 T 29-03-2018 CXR48_RS07195 a3b0056ceb9169ed3b5d91e966b946fd 257 Gene3D G3DSA:3.40.50.1000 118 254 8.1E-22 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS07195 a3b0056ceb9169ed3b5d91e966b946fd 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 249 9.7E-57 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS07195 a3b0056ceb9169ed3b5d91e966b946fd 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 223 1.8E-22 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CXR48_RS07195 a3b0056ceb9169ed3b5d91e966b946fd 257 SUPERFAMILY SSF56784 1 254 6.05E-68 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS07195 a3b0056ceb9169ed3b5d91e966b946fd 257 ProSitePatterns PS01229 Hypothetical cof family signature 2. 204 226 - T 29-03-2018 CXR48_RS07195 a3b0056ceb9169ed3b5d91e966b946fd 257 Gene3D G3DSA:3.40.50.1000 1 117 6.3E-22 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS07195 a3b0056ceb9169ed3b5d91e966b946fd 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 247 1.5E-59 T 29-03-2018 IPR000150 Cof family GO:0016787 CXR48_RS01255 9aa9211cfac45ec5e1f424b41a1bbc8b 295 Gene3D G3DSA:3.20.20.190 26 295 1.9E-82 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CXR48_RS01255 9aa9211cfac45ec5e1f424b41a1bbc8b 295 SUPERFAMILY SSF51695 37 289 8.11E-77 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CXR48_RS01255 9aa9211cfac45ec5e1f424b41a1bbc8b 295 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 43 284 1.6E-59 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CXR48_RS05520 f5b52fb232f97b99423353f0aab1b6bf 59 Pfam PF14168 YjzC-like protein 2 55 3.8E-27 T 29-03-2018 IPR025549 YjzC-like protein CXR48_RS10445 7d96d2b7c220d8203a56df6e0d6156ee 82 SMART SM00530 10 65 2.9E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS10445 7d96d2b7c220d8203a56df6e0d6156ee 82 Gene3D G3DSA:1.10.260.40 1 82 3.4E-16 T 29-03-2018 CXR48_RS10445 7d96d2b7c220d8203a56df6e0d6156ee 82 SUPERFAMILY SSF47413 8 68 2.68E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS10445 7d96d2b7c220d8203a56df6e0d6156ee 82 Pfam PF01381 Helix-turn-helix 11 60 9.7E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS17495 f5bb527829ff37d6466d1359c371a5ff 286 Gene3D G3DSA:3.40.50.150 81 285 1.0E-42 T 29-03-2018 CXR48_RS17495 f5bb527829ff37d6466d1359c371a5ff 286 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 3 285 8.8E-91 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CXR48_RS17495 f5bb527829ff37d6466d1359c371a5ff 286 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 187 193 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CXR48_RS17495 f5bb527829ff37d6466d1359c371a5ff 286 SUPERFAMILY SSF53335 4 280 5.83E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS17495 f5bb527829ff37d6466d1359c371a5ff 286 Pfam PF05175 Methyltransferase small domain 116 220 7.7E-15 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CXR48_RS17495 f5bb527829ff37d6466d1359c371a5ff 286 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 280 4.3E-83 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CXR48_RS17495 f5bb527829ff37d6466d1359c371a5ff 286 Gene3D G3DSA:1.10.8.10 2 80 4.9E-17 T 29-03-2018 CXR48_RS17495 f5bb527829ff37d6466d1359c371a5ff 286 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 284 43.343 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 ProSitePatterns PS01244 Aconitase family signature 2. 508 521 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 Gene3D G3DSA:3.30.499.10 29 246 2.6E-69 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 SUPERFAMILY SSF52016 646 905 1.65E-88 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 ProSitePatterns PS00450 Aconitase family signature 1. 442 458 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 Gene3D G3DSA:3.20.19.10 669 907 3.3E-93 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 Gene3D G3DSA:3.30.499.10 380 591 7.4E-62 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 Pfam PF00694 Aconitase C-terminal domain 707 834 7.5E-47 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 Gene3D G3DSA:3.40.1060.10 247 379 1.1E-42 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 24 906 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 Pfam PF00330 Aconitase family (aconitate hydratase) 85 577 4.1E-173 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 SUPERFAMILY SSF53732 11 642 4.19E-221 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 PRINTS PR00415 Aconitase family signature 224 239 3.2E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 PRINTS PR00415 Aconitase family signature 153 166 3.2E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 PRINTS PR00415 Aconitase family signature 286 299 3.2E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 PRINTS PR00415 Aconitase family signature 380 394 3.2E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 PRINTS PR00415 Aconitase family signature 446 457 3.2E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 PRINTS PR00415 Aconitase family signature 177 185 3.2E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 PRINTS PR00415 Aconitase family signature 300 313 3.2E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 PRINTS PR00415 Aconitase family signature 210 223 3.2E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS08940 0ba2b8fc9bd08fb1a039883ccb6d05f4 908 PRINTS PR00415 Aconitase family signature 508 521 3.2E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS16575 9e6eab860589eecaea2dfca311113097 396 Gene3D G3DSA:2.30.42.10 275 382 2.4E-10 T 29-03-2018 CXR48_RS16575 9e6eab860589eecaea2dfca311113097 396 SMART SM00228 295 361 3.7E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS16575 9e6eab860589eecaea2dfca311113097 396 SUPERFAMILY SSF50156 303 386 3.02E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS08980 2f489a53dd68975b8fdb83b36348419a 193 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 1 192 2.7E-74 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CXR48_RS08980 2f489a53dd68975b8fdb83b36348419a 193 SMART SM01207 8 183 2.4E-80 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CXR48_RS08980 2f489a53dd68975b8fdb83b36348419a 193 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 182 2.8E-52 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CXR48_RS08980 2f489a53dd68975b8fdb83b36348419a 193 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 191 20.399 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CXR48_RS02725 ad6997bf59a8d0ee0bf10e19029a6fb5 349 SUPERFAMILY SSF51735 151 314 1.55E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS02725 ad6997bf59a8d0ee0bf10e19029a6fb5 349 SUPERFAMILY SSF50129 13 174 3.04E-54 T 29-03-2018 IPR011032 GroES-like CXR48_RS02725 ad6997bf59a8d0ee0bf10e19029a6fb5 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CXR48_RS02725 ad6997bf59a8d0ee0bf10e19029a6fb5 349 SMART SM00829 8 344 2.6E-8 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS02725 ad6997bf59a8d0ee0bf10e19029a6fb5 349 Gene3D G3DSA:3.40.50.20 281 344 7.3E-6 T 29-03-2018 CXR48_RS02725 ad6997bf59a8d0ee0bf10e19029a6fb5 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 146 1.1E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS02725 ad6997bf59a8d0ee0bf10e19029a6fb5 349 Pfam PF00107 Zinc-binding dehydrogenase 188 310 1.2E-23 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS02725 ad6997bf59a8d0ee0bf10e19029a6fb5 349 Gene3D G3DSA:3.40.50.720 181 280 9.1E-22 T 29-03-2018 CXR48_RS02725 ad6997bf59a8d0ee0bf10e19029a6fb5 349 Gene3D G3DSA:3.90.180.10 4 180 3.4E-54 T 29-03-2018 CXR48_RS08895 5550d1b59c010251aff6cc912acb8f5e 72 Hamap MF_00363 UPF0154 protein . 2 72 22.651 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 CXR48_RS08895 5550d1b59c010251aff6cc912acb8f5e 72 Pfam PF03672 Uncharacterised protein family (UPF0154) 11 69 3.1E-31 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 CXR48_RS08895 5550d1b59c010251aff6cc912acb8f5e 72 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 1 41 1.0E-6 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 CXR48_RS10725 05eda58c67562d307c78adb0f251f6d6 360 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 359 6.8E-121 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CXR48_RS10725 05eda58c67562d307c78adb0f251f6d6 360 SUPERFAMILY SSF53383 4 360 1.1E-84 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS10725 05eda58c67562d307c78adb0f251f6d6 360 Gene3D G3DSA:3.90.1150.10 268 360 1.3E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS10725 05eda58c67562d307c78adb0f251f6d6 360 Gene3D G3DSA:3.40.640.10 43 267 2.8E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS10725 05eda58c67562d307c78adb0f251f6d6 360 Pfam PF00155 Aminotransferase class I and II 30 354 2.1E-65 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS10725 05eda58c67562d307c78adb0f251f6d6 360 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 360 62.123 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CXR48_RS10725 05eda58c67562d307c78adb0f251f6d6 360 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CXR48_RS03740 9eb6216cd5a3712e7cf9cf2db05574ad 363 Gene3D G3DSA:3.90.1230.10 194 304 1.6E-49 T 29-03-2018 CXR48_RS03740 9eb6216cd5a3712e7cf9cf2db05574ad 363 PIRSF PIRSF037219 1 363 3.1E-189 T 29-03-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 CXR48_RS03740 9eb6216cd5a3712e7cf9cf2db05574ad 363 SUPERFAMILY SSF56512 3 362 9.16E-166 T 29-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CXR48_RS03740 9eb6216cd5a3712e7cf9cf2db05574ad 363 Pfam PF02898 Nitric oxide synthase, oxygenase domain 5 362 7.3E-166 T 29-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CXR48_RS03740 9eb6216cd5a3712e7cf9cf2db05574ad 363 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 65 72 - T 29-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CXR48_RS03740 9eb6216cd5a3712e7cf9cf2db05574ad 363 Gene3D G3DSA:3.90.340.10 1 126 2.8E-47 T 29-03-2018 CXR48_RS09840 768307dd6d13f2df079dfe200ca6c957 318 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 80 152 4.7E-12 T 29-03-2018 IPR024542 Domain of unknown function DUF3880 CXR48_RS09840 768307dd6d13f2df079dfe200ca6c957 318 Gene3D G3DSA:3.40.50.2000 150 301 5.4E-8 T 29-03-2018 CXR48_RS09840 768307dd6d13f2df079dfe200ca6c957 318 SUPERFAMILY SSF53756 39 217 2.12E-9 T 29-03-2018 CXR48_RS09840 768307dd6d13f2df079dfe200ca6c957 318 Pfam PF13524 Glycosyl transferases group 1 211 304 2.5E-11 T 29-03-2018 CXR48_RS04415 ef150fdd937951a15b2c3f1e605b5a7f 89 SUPERFAMILY SSF57716 2 89 9.98E-33 T 29-03-2018 CXR48_RS04415 ef150fdd937951a15b2c3f1e605b5a7f 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 25.422 T 29-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CXR48_RS04415 ef150fdd937951a15b2c3f1e605b5a7f 89 ProSitePatterns PS00527 Ribosomal protein S14 signature. 51 73 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS04415 ef150fdd937951a15b2c3f1e605b5a7f 89 Gene3D G3DSA:4.10.830.10 1 89 4.4E-35 T 29-03-2018 CXR48_RS04415 ef150fdd937951a15b2c3f1e605b5a7f 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 3.3E-28 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS17175 6a1e565b04987638b2cb6fc5d3075e01 113 Gene3D G3DSA:2.40.50.140 1 110 8.2E-39 T 29-03-2018 CXR48_RS17175 6a1e565b04987638b2cb6fc5d3075e01 113 SUPERFAMILY SSF50249 2 108 2.47E-40 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS17175 6a1e565b04987638b2cb6fc5d3075e01 113 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 31.888 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CXR48_RS17175 6a1e565b04987638b2cb6fc5d3075e01 113 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 108 7.0E-35 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CXR48_RS17175 6a1e565b04987638b2cb6fc5d3075e01 113 PIRSF PIRSF002070 2 112 3.6E-31 T 29-03-2018 CXR48_RS17175 6a1e565b04987638b2cb6fc5d3075e01 113 Pfam PF00436 Single-strand binding protein family 2 103 1.4E-33 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 SUPERFAMILY SSF50677 197 347 3.27E-65 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 SUPERFAMILY SSF46589 814 878 2.88E-17 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 565 1.4E-229 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Gene3D G3DSA:3.40.50.620 439 564 2.9E-45 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 PRINTS PR00986 Valyl-tRNA synthetase signature 445 466 6.6E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 6.6E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 6.6E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 6.6E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 PRINTS PR00986 Valyl-tRNA synthetase signature 477 495 6.6E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Pfam PF08264 Anticodon-binding domain of tRNA 608 756 9.4E-44 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 879 4.5E-23 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 TIGRFAM TIGR00422 valS: valine--tRNA ligase 8 861 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Gene3D G3DSA:3.90.740.10 198 241 4.4E-16 T 29-03-2018 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Gene3D G3DSA:1.10.287.380 807 877 2.6E-25 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Gene3D G3DSA:3.40.50.620 22 197 3.8E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Gene3D G3DSA:1.10.730.10 565 746 7.8E-57 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 879 16.259 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 SUPERFAMILY SSF52374 6 198 6.53E-147 T 29-03-2018 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 SUPERFAMILY SSF52374 346 575 6.53E-147 T 29-03-2018 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 Gene3D G3DSA:3.90.740.10 242 438 1.4E-66 T 29-03-2018 CXR48_RS12940 4872f88cdf4595c187c8d21d7fb6251a 880 SUPERFAMILY SSF47323 577 829 2.62E-77 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 Gene3D G3DSA:3.40.50.720 41 259 8.2E-66 T 29-03-2018 CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 Gene3D G3DSA:3.40.50.720 1 40 1.6E-8 T 29-03-2018 CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 SUPERFAMILY SSF51735 6 253 8.0E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 1.7E-67 T 29-03-2018 CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS01515 10beba505fd50bd3551378b5f07d311f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS10715 bf62fa21f3fe539da53574aeb85e1ee0 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 5 421 5.8E-125 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CXR48_RS10715 bf62fa21f3fe539da53574aeb85e1ee0 428 ProSitePatterns PS00885 EPSP synthase signature 2. 337 355 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CXR48_RS10715 bf62fa21f3fe539da53574aeb85e1ee0 428 Gene3D G3DSA:3.65.10.10 217 427 3.6E-54 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CXR48_RS10715 bf62fa21f3fe539da53574aeb85e1ee0 428 Gene3D G3DSA:3.65.10.10 18 216 2.4E-56 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CXR48_RS10715 bf62fa21f3fe539da53574aeb85e1ee0 428 ProSitePatterns PS00104 EPSP synthase signature 1. 85 99 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CXR48_RS10715 bf62fa21f3fe539da53574aeb85e1ee0 428 SUPERFAMILY SSF55205 4 424 2.94E-134 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CXR48_RS10715 bf62fa21f3fe539da53574aeb85e1ee0 428 PIRSF PIRSF000505 2 428 4.3E-120 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CXR48_RS10715 bf62fa21f3fe539da53574aeb85e1ee0 428 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 11 426 1.9E-131 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CXR48_RS10715 bf62fa21f3fe539da53574aeb85e1ee0 428 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 7 427 34.729 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CXR48_RS16320 c5bf25d355b397295fe1015c04ec8e28 458 SUPERFAMILY SSF103473 10 443 3.27E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS16320 c5bf25d355b397295fe1015c04ec8e28 458 Pfam PF00083 Sugar (and other) transporter 25 441 1.8E-34 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CXR48_RS16320 c5bf25d355b397295fe1015c04ec8e28 458 Gene3D G3DSA:1.20.1250.20 237 457 2.1E-26 T 29-03-2018 CXR48_RS16320 c5bf25d355b397295fe1015c04ec8e28 458 Gene3D G3DSA:1.20.1250.20 3 230 1.0E-32 T 29-03-2018 CXR48_RS10695 7f7b5ac5e7093f5474beea5929beaa08 167 Pfam PF08802 Cytochrome B6-F complex Fe-S subunit 6 35 7.0E-7 T 29-03-2018 IPR014909 Cytochrome b6-f complex Fe-S subunit GO:0009496|GO:0042651|GO:0051537|GO:0055114 KEGG: 00195+1.10.9.1|MetaCyc: PWY-101 CXR48_RS10695 7f7b5ac5e7093f5474beea5929beaa08 167 Gene3D G3DSA:1.20.5.700 2 39 4.9E-17 T 29-03-2018 CXR48_RS10695 7f7b5ac5e7093f5474beea5929beaa08 167 Pfam PF00355 Rieske [2Fe-2S] domain 78 147 2.1E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CXR48_RS10695 7f7b5ac5e7093f5474beea5929beaa08 167 Gene3D G3DSA:2.102.10.10 41 166 1.1E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CXR48_RS10695 7f7b5ac5e7093f5474beea5929beaa08 167 SUPERFAMILY SSF50022 4 158 2.23E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CXR48_RS15845 94c7914a44d852553aad87c532a1bed1 61 SMART SM00530 1 51 0.0057 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS15845 94c7914a44d852553aad87c532a1bed1 61 Pfam PF01381 Helix-turn-helix 4 50 1.8E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS15845 94c7914a44d852553aad87c532a1bed1 61 SUPERFAMILY SSF47413 4 55 3.76E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS15845 94c7914a44d852553aad87c532a1bed1 61 Gene3D G3DSA:1.10.260.40 2 61 1.5E-9 T 29-03-2018 CXR48_RS02575 a72b90ed0c4f487eb9d4e3c89a46e0e5 212 Gene3D G3DSA:3.40.50.720 1 210 1.5E-20 T 29-03-2018 CXR48_RS02575 a72b90ed0c4f487eb9d4e3c89a46e0e5 212 SUPERFAMILY SSF51735 2 210 6.99E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS02575 a72b90ed0c4f487eb9d4e3c89a46e0e5 212 Pfam PF13460 NAD(P)H-binding 7 195 2.6E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01360 3507a3c008d56af692419749e9b77025 327 Gene3D G3DSA:3.40.710.10 8 327 1.3E-115 T 29-03-2018 CXR48_RS01360 3507a3c008d56af692419749e9b77025 327 SUPERFAMILY SSF56601 3 327 1.13E-121 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS01360 3507a3c008d56af692419749e9b77025 327 TIGRFAM TIGR03814 Gln_ase: glutaminase A 18 327 1.1E-120 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CXR48_RS01360 3507a3c008d56af692419749e9b77025 327 Pfam PF04960 Glutaminase 32 327 1.1E-106 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CXR48_RS01360 3507a3c008d56af692419749e9b77025 327 Hamap MF_00313 Glutaminase [glsA]. 14 327 44.329 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CXR48_RS11875 5c411184fe734970896650aba04b8b7c 345 Pfam PF00482 Type II secretion system (T2SS), protein F 16 136 4.7E-12 T 29-03-2018 IPR018076 Type II secretion system F domain CXR48_RS11875 5c411184fe734970896650aba04b8b7c 345 Pfam PF00482 Type II secretion system (T2SS), protein F 215 337 4.0E-20 T 29-03-2018 IPR018076 Type II secretion system F domain CXR48_RS11875 5c411184fe734970896650aba04b8b7c 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 38 50 7.9E-5 T 29-03-2018 IPR003004 GspF/PilC family CXR48_RS11875 5c411184fe734970896650aba04b8b7c 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 310 324 7.9E-5 T 29-03-2018 IPR003004 GspF/PilC family CXR48_RS11875 5c411184fe734970896650aba04b8b7c 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 326 345 7.9E-5 T 29-03-2018 IPR003004 GspF/PilC family CXR48_RS17135 a1b2a42b52e92305ef2cf4a026051f03 229 Gene3D G3DSA:3.40.50.300 11 225 3.1E-36 T 29-03-2018 CXR48_RS17135 a1b2a42b52e92305ef2cf4a026051f03 229 Pfam PF13614 AAA domain 57 174 2.3E-13 T 29-03-2018 IPR025669 AAA domain CXR48_RS17135 a1b2a42b52e92305ef2cf4a026051f03 229 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 26 228 2.5E-64 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CXR48_RS17135 a1b2a42b52e92305ef2cf4a026051f03 229 SUPERFAMILY SSF52540 46 219 1.27E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03205 15f0935f64841e753939dab9c94f167f 461 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CXR48_RS03205 15f0935f64841e753939dab9c94f167f 461 TIGRFAM TIGR01773 GABAperm: GABA permease 3 449 8.1E-225 T 29-03-2018 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 CXR48_RS03205 15f0935f64841e753939dab9c94f167f 461 Pfam PF00324 Amino acid permease 15 450 2.6E-127 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS03205 15f0935f64841e753939dab9c94f167f 461 PIRSF PIRSF006060 1 459 2.7E-77 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS02675 d6beb6f3a69bfd8b4cb2754ffef972db 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 290 2.7E-95 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CXR48_RS02675 d6beb6f3a69bfd8b4cb2754ffef972db 313 Pfam PF16916 Dimerisation domain of Zinc Transporter 220 288 2.0E-6 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CXR48_RS02675 d6beb6f3a69bfd8b4cb2754ffef972db 313 SUPERFAMILY SSF160240 214 289 1.96E-12 T 29-03-2018 CXR48_RS02675 d6beb6f3a69bfd8b4cb2754ffef972db 313 Pfam PF01545 Cation efflux family 16 209 3.9E-50 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CXR48_RS02675 d6beb6f3a69bfd8b4cb2754ffef972db 313 Gene3D G3DSA:3.30.70.1350 211 293 4.5E-17 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CXR48_RS02675 d6beb6f3a69bfd8b4cb2754ffef972db 313 SUPERFAMILY SSF161111 12 210 7.72E-60 T 29-03-2018 CXR48_RS02675 d6beb6f3a69bfd8b4cb2754ffef972db 313 Gene3D G3DSA:1.20.1510.10 11 209 7.1E-61 T 29-03-2018 CXR48_RS03660 644c2ced714ab9868426b37bb9b151d3 339 SUPERFAMILY SSF51735 123 300 1.75E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS03660 644c2ced714ab9868426b37bb9b151d3 339 SUPERFAMILY SSF50129 6 142 8.81E-37 T 29-03-2018 IPR011032 GroES-like CXR48_RS03660 644c2ced714ab9868426b37bb9b151d3 339 SMART SM00829 18 333 5.2E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS03660 644c2ced714ab9868426b37bb9b151d3 339 Gene3D G3DSA:3.40.50.720 148 276 8.6E-29 T 29-03-2018 CXR48_RS03660 644c2ced714ab9868426b37bb9b151d3 339 Gene3D G3DSA:3.90.180.10 1 147 3.9E-38 T 29-03-2018 CXR48_RS03660 644c2ced714ab9868426b37bb9b151d3 339 Pfam PF16884 N-terminal domain of oxidoreductase 7 111 1.3E-35 T 29-03-2018 CXR48_RS03660 644c2ced714ab9868426b37bb9b151d3 339 Pfam PF00107 Zinc-binding dehydrogenase 157 294 2.3E-22 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS09695 e727dd5d596831ca192d59a34babbeb7 492 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 425 486 9.8E-13 T 29-03-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 CXR48_RS09695 e727dd5d596831ca192d59a34babbeb7 492 PRINTS PR00843 Glycosyl hydrolase family 30 signature 221 238 9.4E-9 T 29-03-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 CXR48_RS09695 e727dd5d596831ca192d59a34babbeb7 492 PRINTS PR00843 Glycosyl hydrolase family 30 signature 123 149 9.4E-9 T 29-03-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 CXR48_RS09695 e727dd5d596831ca192d59a34babbeb7 492 PRINTS PR00843 Glycosyl hydrolase family 30 signature 87 107 9.4E-9 T 29-03-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 CXR48_RS09695 e727dd5d596831ca192d59a34babbeb7 492 Gene3D G3DSA:2.60.40.1180 419 492 2.4E-16 T 29-03-2018 CXR48_RS09695 e727dd5d596831ca192d59a34babbeb7 492 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 98 422 1.1E-31 T 29-03-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 CXR48_RS09695 e727dd5d596831ca192d59a34babbeb7 492 SUPERFAMILY SSF51445 98 426 2.36E-62 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS09695 e727dd5d596831ca192d59a34babbeb7 492 Gene3D G3DSA:3.20.20.80 95 418 1.2E-73 T 29-03-2018 CXR48_RS05405 3e56fefb95855ada171c664939a342af 613 Pfam PF02574 Homocysteine S-methyltransferase 12 280 9.3E-60 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CXR48_RS05405 3e56fefb95855ada171c664939a342af 613 SUPERFAMILY SSF82282 2 360 1.19E-99 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CXR48_RS05405 3e56fefb95855ada171c664939a342af 613 Pfam PF02219 Methylenetetrahydrofolate reductase 314 571 6.2E-26 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CXR48_RS05405 3e56fefb95855ada171c664939a342af 613 SUPERFAMILY SSF51730 314 601 9.81E-64 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CXR48_RS05405 3e56fefb95855ada171c664939a342af 613 Gene3D G3DSA:3.20.20.220 315 612 9.8E-60 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CXR48_RS05405 3e56fefb95855ada171c664939a342af 613 Gene3D G3DSA:3.20.20.330 1 314 1.2E-84 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CXR48_RS02160 758f32505e9115f1a844005737501206 167 SUPERFAMILY SSF51182 44 158 1.39E-9 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS02160 758f32505e9115f1a844005737501206 167 Gene3D G3DSA:2.60.120.10 1 166 1.0E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 SUPERFAMILY SSF53223 85 234 3.53E-49 T 29-03-2018 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 Gene3D G3DSA:3.40.50.10380 84 233 1.2E-34 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 SMART SM00919 236 435 6.3E-43 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 Gene3D G3DSA:3.30.70.260 4 83 1.8E-5 T 29-03-2018 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 Pfam PF00390 Malic enzyme, N-terminal domain 95 224 1.1E-25 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 262 324 1.6E-4 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 SMART SM01274 91 224 8.1E-68 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 Pfam PF03949 Malic enzyme, NAD binding domain 371 424 3.7E-6 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 ProSitePatterns PS00331 Malic enzymes signature. 232 248 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 PIRSF PIRSF000106 1 437 8.9E-79 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 Gene3D G3DSA:3.40.50.720 234 437 4.2E-36 T 29-03-2018 CXR48_RS11180 fd1fde8fb11284aa3802064a5ca79c38 437 SUPERFAMILY SSF51735 236 434 7.37E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS16725 7d0aeeeae6d6efec2dee45d40da060f1 215 SUPERFAMILY SSF54211 1 131 1.52E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS16725 7d0aeeeae6d6efec2dee45d40da060f1 215 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 1.3E-17 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CXR48_RS16725 7d0aeeeae6d6efec2dee45d40da060f1 215 Gene3D G3DSA:3.30.70.240 135 197 1.8E-15 T 29-03-2018 CXR48_RS16725 7d0aeeeae6d6efec2dee45d40da060f1 215 Pfam PF01205 Uncharacterized protein family UPF0029 20 123 2.2E-32 T 29-03-2018 IPR001498 Impact, N-terminal CXR48_RS16725 7d0aeeeae6d6efec2dee45d40da060f1 215 SUPERFAMILY SSF54980 135 198 4.39E-9 T 29-03-2018 IPR035647 EF-G domain III/V-like CXR48_RS16725 7d0aeeeae6d6efec2dee45d40da060f1 215 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 200 4.5E-87 T 29-03-2018 IPR015796 Impact family, bacterial/archaeal CXR48_RS16725 7d0aeeeae6d6efec2dee45d40da060f1 215 Gene3D G3DSA:3.30.230.30 4 133 3.8E-46 T 29-03-2018 IPR001498 Impact, N-terminal CXR48_RS16725 7d0aeeeae6d6efec2dee45d40da060f1 215 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 29-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CXR48_RS01200 7b45805110b72a309e6e99ac3edf4c70 417 Gene3D G3DSA:3.30.70.250 140 187 1.6E-15 T 29-03-2018 CXR48_RS01200 7b45805110b72a309e6e99ac3edf4c70 417 Pfam PF00698 Acyl transferase domain 6 290 1.4E-40 T 29-03-2018 IPR014043 Acyl transferase CXR48_RS01200 7b45805110b72a309e6e99ac3edf4c70 417 SUPERFAMILY SSF55048 128 197 2.88E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CXR48_RS01200 7b45805110b72a309e6e99ac3edf4c70 417 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 321 8.2E-33 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CXR48_RS01200 7b45805110b72a309e6e99ac3edf4c70 417 Gene3D G3DSA:3.40.366.10 188 312 8.7E-22 T 29-03-2018 CXR48_RS01200 7b45805110b72a309e6e99ac3edf4c70 417 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 287 1.7E-86 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS01200 7b45805110b72a309e6e99ac3edf4c70 417 Gene3D G3DSA:3.40.366.10 3 139 2.5E-40 T 29-03-2018 CXR48_RS01200 7b45805110b72a309e6e99ac3edf4c70 417 SUPERFAMILY SSF52151 198 297 2.62E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS01200 7b45805110b72a309e6e99ac3edf4c70 417 SUPERFAMILY SSF52151 3 128 2.62E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS14115 0adb97ac7dfa41c377730869d86c01ba 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 3.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14115 0adb97ac7dfa41c377730869d86c01ba 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 198 212 3.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14115 0adb97ac7dfa41c377730869d86c01ba 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 3.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS14115 0adb97ac7dfa41c377730869d86c01ba 259 Gene3D G3DSA:3.40.50.1820 1 259 9.0E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14115 0adb97ac7dfa41c377730869d86c01ba 259 Pfam PF12146 Serine aminopeptidase, S33 8 243 9.7E-60 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CXR48_RS14115 0adb97ac7dfa41c377730869d86c01ba 259 SUPERFAMILY SSF53474 5 258 1.85E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS10670 e8a52d03c7baace42434a4f0a1b848b4 391 SUPERFAMILY SSF51182 15 384 7.22E-105 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS10670 e8a52d03c7baace42434a4f0a1b848b4 391 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 20 385 4.1E-175 T 29-03-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 CXR48_RS10670 e8a52d03c7baace42434a4f0a1b848b4 391 Gene3D G3DSA:2.60.120.10 219 390 4.0E-40 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS10670 e8a52d03c7baace42434a4f0a1b848b4 391 Gene3D G3DSA:2.60.120.10 7 212 1.7E-49 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS10670 e8a52d03c7baace42434a4f0a1b848b4 391 SMART SM00835 234 375 1.4E-32 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS10670 e8a52d03c7baace42434a4f0a1b848b4 391 SMART SM00835 56 198 8.2E-21 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS10670 e8a52d03c7baace42434a4f0a1b848b4 391 Pfam PF00190 Cupin 236 371 3.8E-20 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS10670 e8a52d03c7baace42434a4f0a1b848b4 391 Pfam PF00190 Cupin 67 192 1.0E-21 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS16660 7a14462b9b10b52b4fef3ae01756af3e 143 Pfam PF02623 FliW protein 19 137 1.7E-39 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CXR48_RS16660 7a14462b9b10b52b4fef3ae01756af3e 143 SUPERFAMILY SSF141457 1 138 2.75E-49 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain CXR48_RS16660 7a14462b9b10b52b4fef3ae01756af3e 143 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 141 25.021 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CXR48_RS16660 7a14462b9b10b52b4fef3ae01756af3e 143 Gene3D G3DSA:2.30.290.10 1 141 2.6E-52 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain CXR48_RS00860 608809e732b4bd5a9ebf3fc55cc4543b 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00860 608809e732b4bd5a9ebf3fc55cc4543b 37 SUPERFAMILY SSF57840 1 37 6.28E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00860 608809e732b4bd5a9ebf3fc55cc4543b 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 2.0E-8 T 29-03-2018 CXR48_RS00860 608809e732b4bd5a9ebf3fc55cc4543b 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.611 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00860 608809e732b4bd5a9ebf3fc55cc4543b 37 Pfam PF00444 Ribosomal protein L36 1 37 3.2E-19 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00860 608809e732b4bd5a9ebf3fc55cc4543b 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 5.8E-24 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 29-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 Pfam PF10509 Galactokinase galactose-binding signature 9 56 5.1E-20 T 29-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 Gene3D G3DSA:3.30.70.890 208 376 4.5E-56 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 PRINTS PR00473 Galactokinase signature 269 283 6.7E-27 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 PRINTS PR00473 Galactokinase signature 26 44 6.7E-27 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 PRINTS PR00473 Galactokinase signature 91 102 6.7E-27 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 PRINTS PR00473 Galactokinase signature 112 130 6.7E-27 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 Gene3D G3DSA:3.30.230.10 3 207 6.9E-52 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 TIGRFAM TIGR00131 gal_kin: galactokinase 6 384 3.6E-118 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 SUPERFAMILY SSF54211 6 201 5.39E-60 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 Hamap MF_00246 Galactokinase [galK]. 24 385 46.214 T 29-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 PRINTS PR00959 Mevalonate kinase family signature 119 141 2.2E-42 T 29-03-2018 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 PRINTS PR00959 Mevalonate kinase family signature 332 349 2.2E-42 T 29-03-2018 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 PRINTS PR00959 Mevalonate kinase family signature 162 181 2.2E-42 T 29-03-2018 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 PRINTS PR00959 Mevalonate kinase family signature 24 48 2.2E-42 T 29-03-2018 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 PIRSF PIRSF000530 1 387 2.7E-123 T 29-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 Pfam PF08544 GHMP kinases C terminal 285 358 5.2E-15 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 Pfam PF00288 GHMP kinases N terminal domain 114 177 2.5E-10 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CXR48_RS05945 804a5e0de8225377cb98925d352ac42f 389 SUPERFAMILY SSF55060 205 384 6.24E-56 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CXR48_RS14220 dc80f94cd88bd1cb35ede0f1ff018a78 346 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 8 335 4.2E-35 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CXR48_RS19155 0d76b8cad494fcda744a0e3fbb320c65 123 SUPERFAMILY SSF46785 6 105 1.07E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19155 0d76b8cad494fcda744a0e3fbb320c65 123 Gene3D G3DSA:1.10.10.10 16 123 4.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19155 0d76b8cad494fcda744a0e3fbb320c65 123 Pfam PF01638 HxlR-like helix-turn-helix 18 104 7.3E-39 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CXR48_RS01370 08ec6ec8fa1e3d8d770ff233cc5a2cce 315 Pfam PF00072 Response regulator receiver domain 4 114 3.9E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS01370 08ec6ec8fa1e3d8d770ff233cc5a2cce 315 Gene3D G3DSA:3.40.50.2300 1 146 1.7E-21 T 29-03-2018 CXR48_RS01370 08ec6ec8fa1e3d8d770ff233cc5a2cce 315 Pfam PF08664 YcbB domain 160 296 5.8E-45 T 29-03-2018 IPR013972 YcbB domain CXR48_RS01370 08ec6ec8fa1e3d8d770ff233cc5a2cce 315 SUPERFAMILY SSF52172 2 137 3.13E-23 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS01370 08ec6ec8fa1e3d8d770ff233cc5a2cce 315 SMART SM00448 1 114 2.9E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS18705 eeaae09ede431f99a67b8e531b9ae08b 431 Gene3D G3DSA:1.20.1250.20 207 416 6.9E-24 T 29-03-2018 CXR48_RS18705 eeaae09ede431f99a67b8e531b9ae08b 431 Pfam PF07690 Major Facilitator Superfamily 32 363 1.6E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS18705 eeaae09ede431f99a67b8e531b9ae08b 431 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS18705 eeaae09ede431f99a67b8e531b9ae08b 431 Gene3D G3DSA:1.20.1250.20 6 206 1.5E-28 T 29-03-2018 CXR48_RS18705 eeaae09ede431f99a67b8e531b9ae08b 431 ProSitePatterns PS00217 Sugar transport proteins signature 2. 111 136 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS18705 eeaae09ede431f99a67b8e531b9ae08b 431 SUPERFAMILY SSF103473 14 413 7.19E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 1 495 2.2E-302 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PIRSF PIRSF006615 2 500 8.9E-200 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 SUPERFAMILY SSF55486 6 495 1.57E-112 T 29-03-2018 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 228 244 3.3E-89 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 402 423 3.3E-89 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 265 284 3.3E-89 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 333 352 3.3E-89 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 379 396 3.3E-89 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 148 168 3.3E-89 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 447 465 3.3E-89 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 245 264 3.3E-89 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 292 308 3.3E-89 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CXR48_RS10470 775f4fb6916a2cf6d1342a550f2695fb 500 Gene3D G3DSA:1.10.1370.10 15 497 3.0E-42 T 29-03-2018 CXR48_RS19430 f8b58b7f1414819135b72b43863e65d2 116 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 100 5.0E-39 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CXR48_RS19430 f8b58b7f1414819135b72b43863e65d2 116 Gene3D G3DSA:3.30.230.10 1 116 5.5E-37 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS19430 f8b58b7f1414819135b72b43863e65d2 116 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 29-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CXR48_RS19430 f8b58b7f1414819135b72b43863e65d2 116 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 110 20.341 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CXR48_RS19430 f8b58b7f1414819135b72b43863e65d2 116 Pfam PF00825 Ribonuclease P 2 107 2.6E-34 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CXR48_RS19430 f8b58b7f1414819135b72b43863e65d2 116 SUPERFAMILY SSF54211 2 111 6.07E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS19430 f8b58b7f1414819135b72b43863e65d2 116 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 110 1.1E-36 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 290 1.8E-26 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 SUPERFAMILY SSF55048 121 188 1.44E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 Gene3D G3DSA:3.40.366.10 1 133 3.4E-34 T 29-03-2018 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 SUPERFAMILY SSF51395 311 569 9.7E-27 T 29-03-2018 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 Pfam PF03060 Nitronate monooxygenase 322 588 1.7E-8 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 281 1.2E-110 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 Pfam PF00698 Acyl transferase domain 3 281 1.7E-36 T 29-03-2018 IPR014043 Acyl transferase CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 311 745 7.2E-210 T 29-03-2018 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 SUPERFAMILY SSF52151 1 117 1.49E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 SUPERFAMILY SSF52151 181 290 1.49E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 Gene3D G3DSA:3.30.70.250 134 182 2.1E-17 T 29-03-2018 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 Gene3D G3DSA:3.40.366.10 183 299 1.5E-19 T 29-03-2018 CXR48_RS11385 56db5bf098db59ef07fa141fc0eff4ed 752 Gene3D G3DSA:3.20.20.70 303 742 7.9E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS10920 52caa7c88e47a24e98f9abe41e42c408 496 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 7 349 4.3E-106 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CXR48_RS10920 52caa7c88e47a24e98f9abe41e42c408 496 Pfam PF00271 Helicase conserved C-terminal domain 215 323 1.1E-16 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS10920 52caa7c88e47a24e98f9abe41e42c408 496 SUPERFAMILY SSF52540 57 346 9.34E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10920 52caa7c88e47a24e98f9abe41e42c408 496 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 131 140 - T 29-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site CXR48_RS10920 52caa7c88e47a24e98f9abe41e42c408 496 SMART SM00490 242 324 1.0E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS10920 52caa7c88e47a24e98f9abe41e42c408 496 Pfam PF00270 DEAD/DEAH box helicase 20 178 3.3E-19 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CXR48_RS10920 52caa7c88e47a24e98f9abe41e42c408 496 Gene3D G3DSA:3.40.50.300 200 461 4.9E-44 T 29-03-2018 CXR48_RS10920 52caa7c88e47a24e98f9abe41e42c408 496 SMART SM00487 13 199 3.4E-23 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS10920 52caa7c88e47a24e98f9abe41e42c408 496 Gene3D G3DSA:3.40.50.300 1 196 7.7E-33 T 29-03-2018 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 SMART SM00363 351 413 4.5E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 Pfam PF00579 tRNA synthetases class I (W and Y) 46 332 5.3E-78 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 SUPERFAMILY SSF55174 335 411 3.53E-19 T 29-03-2018 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 12 412 44.502 T 29-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 15 412 3.5E-134 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 56 66 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 Pfam PF01479 S4 domain 353 391 1.5E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 Gene3D G3DSA:1.10.240.10 233 324 8.1E-27 T 29-03-2018 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 Gene3D G3DSA:3.10.290.10 325 414 5.6E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 SUPERFAMILY SSF52374 17 331 6.7E-85 T 29-03-2018 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 Gene3D G3DSA:3.40.50.620 9 232 2.6E-55 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 225 237 7.1E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 175 190 7.1E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 192 214 7.1E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS18210 87ae9622f45a49e91637caae9513d0f5 414 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 60 82 7.1E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 12 434 5.3E-138 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 PIRSF PIRSF000774 1 437 1.1E-124 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 Pfam PF04552 Sigma-54, DNA binding domain 276 435 2.1E-61 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 Gene3D G3DSA:1.10.10.10 281 373 2.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 8.9E-12 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 PRINTS PR00045 Sigma-54 factor signature 147 164 3.4E-25 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 PRINTS PR00045 Sigma-54 factor signature 351 362 3.4E-25 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 PRINTS PR00045 Sigma-54 factor signature 335 347 3.4E-25 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 PRINTS PR00045 Sigma-54 factor signature 410 428 3.4E-25 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 323 342 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 Pfam PF04963 Sigma-54 factor, core binding domain 79 262 5.3E-50 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CXR48_RS16125 2da8630882fdc586b784c9af04c05cd7 437 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 415 422 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11665 3ad0b0f3555d80713cfd602511169f70 84 Gene3D G3DSA:1.10.287.1040 9 74 2.1E-24 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CXR48_RS11665 3ad0b0f3555d80713cfd602511169f70 84 Pfam PF02609 Exonuclease VII small subunit 12 61 1.1E-20 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CXR48_RS11665 3ad0b0f3555d80713cfd602511169f70 84 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 11 66 1.4E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CXR48_RS11665 3ad0b0f3555d80713cfd602511169f70 84 SUPERFAMILY SSF116842 5 74 1.44E-21 T 29-03-2018 CXR48_RS11665 3ad0b0f3555d80713cfd602511169f70 84 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 11 71 14.484 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CXR48_RS11665 3ad0b0f3555d80713cfd602511169f70 84 PIRSF PIRSF006488 1 83 1.2E-20 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CXR48_RS11665 3ad0b0f3555d80713cfd602511169f70 84 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 11 50 1.0E-15 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CXR48_RS00855 282aa395aea73944db10ffebf2ea0e27 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.425 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CXR48_RS00855 282aa395aea73944db10ffebf2ea0e27 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 4.6E-40 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CXR48_RS00855 282aa395aea73944db10ffebf2ea0e27 72 SUPERFAMILY SSF50249 1 71 4.65E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS00855 282aa395aea73944db10ffebf2ea0e27 72 Gene3D G3DSA:2.40.50.140 1 72 2.4E-38 T 29-03-2018 CXR48_RS00855 282aa395aea73944db10ffebf2ea0e27 72 SMART SM00316 4 72 1.5E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS00855 282aa395aea73944db10ffebf2ea0e27 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 9.2E-29 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.9E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 Gene3D G3DSA:1.10.10.10 1 83 3.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 Gene3D G3DSA:3.40.190.10 87 180 5.6E-18 T 29-03-2018 CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 SUPERFAMILY SSF53850 88 292 8.15E-42 T 29-03-2018 CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 Gene3D G3DSA:3.40.190.10 181 266 6.3E-20 T 29-03-2018 CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 SUPERFAMILY SSF46785 1 86 7.41E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17060 9c7098a1aae6599e504b6a311337e052 293 Pfam PF03466 LysR substrate binding domain 86 292 4.8E-49 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS06715 e42cdf93b4ad73ee4875fdf1d9aa8fef 353 SUPERFAMILY SSF100950 6 343 1.4E-114 T 29-03-2018 CXR48_RS06715 e42cdf93b4ad73ee4875fdf1d9aa8fef 353 Gene3D G3DSA:3.40.50.10470 143 350 4.2E-66 T 29-03-2018 CXR48_RS06715 e42cdf93b4ad73ee4875fdf1d9aa8fef 353 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 347 39.036 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CXR48_RS06715 e42cdf93b4ad73ee4875fdf1d9aa8fef 353 Gene3D G3DSA:1.20.120.420 6 142 9.8E-46 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CXR48_RS06715 e42cdf93b4ad73ee4875fdf1d9aa8fef 353 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 36 336 1.0E-131 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CXR48_RS06715 e42cdf93b4ad73ee4875fdf1d9aa8fef 353 Pfam PF01008 Initiation factor 2 subunit family 49 336 2.5E-89 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CXR48_RS06715 e42cdf93b4ad73ee4875fdf1d9aa8fef 353 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 336 1.1E-139 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CXR48_RS12490 5b2d3cd109409594514a5123f57da16a 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CXR48_RS12490 5b2d3cd109409594514a5123f57da16a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 3.1E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS12490 5b2d3cd109409594514a5123f57da16a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 3.1E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS12490 5b2d3cd109409594514a5123f57da16a 188 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 57 186 3.2E-44 T 29-03-2018 IPR032551 HTH-type transcriptional repressor, C-terminal CXR48_RS12490 5b2d3cd109409594514a5123f57da16a 188 SUPERFAMILY SSF46689 4 69 4.54E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS12490 5b2d3cd109409594514a5123f57da16a 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 2.4E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS12490 5b2d3cd109409594514a5123f57da16a 188 Gene3D G3DSA:1.10.10.60 43 132 8.1E-10 T 29-03-2018 CXR48_RS12490 5b2d3cd109409594514a5123f57da16a 188 Gene3D G3DSA:1.10.10.60 4 42 1.6E-14 T 29-03-2018 CXR48_RS03395 d5922da0099f4f662965f0bb1ad4da33 485 Gene3D G3DSA:3.90.1300.10 1 485 7.5E-176 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CXR48_RS03395 d5922da0099f4f662965f0bb1ad4da33 485 ProSitePatterns PS00571 Amidases signature. 152 183 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CXR48_RS03395 d5922da0099f4f662965f0bb1ad4da33 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 97.285 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CXR48_RS03395 d5922da0099f4f662965f0bb1ad4da33 485 SUPERFAMILY SSF75304 1 483 7.19E-171 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CXR48_RS03395 d5922da0099f4f662965f0bb1ad4da33 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 11 477 2.1E-213 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CXR48_RS03395 d5922da0099f4f662965f0bb1ad4da33 485 Pfam PF01425 Amidase 24 465 3.5E-166 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CXR48_RS16370 511d8618c3d4dd2f24a7f5e5863fc502 316 Gene3D G3DSA:3.10.28.10 1 107 1.1E-13 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CXR48_RS16370 511d8618c3d4dd2f24a7f5e5863fc502 316 Gene3D G3DSA:3.10.28.10 112 212 6.3E-19 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CXR48_RS16370 511d8618c3d4dd2f24a7f5e5863fc502 316 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 2.0E-131 T 29-03-2018 IPR033981 Sporulation regulator WhiA-like CXR48_RS16370 511d8618c3d4dd2f24a7f5e5863fc502 316 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 18 103 5.8E-37 T 29-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CXR48_RS16370 511d8618c3d4dd2f24a7f5e5863fc502 316 Pfam PF02650 WhiA C-terminal HTH domain 220 304 1.9E-35 T 29-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CXR48_RS16370 511d8618c3d4dd2f24a7f5e5863fc502 316 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 35.522 T 29-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CXR48_RS16370 511d8618c3d4dd2f24a7f5e5863fc502 316 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 4.2E-36 T 29-03-2018 CXR48_RS16370 511d8618c3d4dd2f24a7f5e5863fc502 316 SUPERFAMILY SSF55608 119 221 5.16E-19 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CXR48_RS11320 7e910b181e93257ebe1e2b52ac836cea 415 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 273 411 1.7E-12 T 29-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CXR48_RS11320 7e910b181e93257ebe1e2b52ac836cea 415 Gene3D G3DSA:3.40.47.10 16 183 1.2E-7 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11320 7e910b181e93257ebe1e2b52ac836cea 415 SUPERFAMILY SSF53901 185 413 3.51E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11320 7e910b181e93257ebe1e2b52ac836cea 415 Gene3D G3DSA:3.40.47.10 190 339 1.9E-34 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11320 7e910b181e93257ebe1e2b52ac836cea 415 SUPERFAMILY SSF53901 2 180 1.46E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11320 7e910b181e93257ebe1e2b52ac836cea 415 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 177 1.6E-8 T 29-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 SUPERFAMILY SSF54106 27 71 2.49E-9 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 SUPERFAMILY SSF54106 219 264 5.89E-11 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 SMART SM00257 154 197 1.4E-18 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 SMART SM00257 28 71 1.8E-13 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 SMART SM00257 89 132 1.4E-16 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 SMART SM00257 221 264 1.9E-16 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 SUPERFAMILY SSF54106 154 197 7.98E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Pfam PF00877 NlpC/P60 family 310 410 2.0E-28 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Gene3D G3DSA:3.10.350.10 85 136 1.7E-15 T 29-03-2018 CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 SUPERFAMILY SSF54001 291 412 3.68E-32 T 29-03-2018 CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 SUPERFAMILY SSF54106 89 131 1.57E-11 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Gene3D G3DSA:3.90.1720.10 294 412 5.9E-29 T 29-03-2018 CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Gene3D G3DSA:3.10.350.10 147 216 1.0E-17 T 29-03-2018 CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Gene3D G3DSA:3.10.350.10 217 292 4.6E-16 T 29-03-2018 CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Gene3D G3DSA:3.10.350.10 21 84 7.5E-13 T 29-03-2018 CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Pfam PF01476 LysM domain 90 132 6.0E-16 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Pfam PF01476 LysM domain 222 263 2.9E-14 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Pfam PF01476 LysM domain 155 197 1.8E-15 T 29-03-2018 IPR018392 LysM domain CXR48_RS09600 a3ef64fb8f6849c54a91e2e8307b7820 413 Pfam PF01476 LysM domain 30 71 2.9E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 Gene3D G3DSA:3.40.190.10 180 267 3.3E-22 T 29-03-2018 CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 4.4E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 Pfam PF03466 LysR substrate binding domain 90 293 3.4E-47 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 Gene3D G3DSA:1.10.10.10 1 83 5.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 SUPERFAMILY SSF46785 4 111 7.99E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 SUPERFAMILY SSF53850 90 296 5.0E-41 T 29-03-2018 CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS17800 24a0769ce146321907920b6f6791d70e 299 Gene3D G3DSA:3.40.190.10 88 179 3.7E-25 T 29-03-2018 CXR48_RS18130 b43f8ada7a8f78266aa12c6362918a75 200 SUPERFAMILY SSF52833 1 199 8.69E-43 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS18130 b43f8ada7a8f78266aa12c6362918a75 200 Gene3D G3DSA:3.40.30.10 1 199 5.6E-50 T 29-03-2018 CXR48_RS18130 b43f8ada7a8f78266aa12c6362918a75 200 Pfam PF01323 DSBA-like thioredoxin domain 4 193 2.3E-40 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CXR48_RS01530 2622b295d2701dfdbc7aac01e3d9ea5b 231 Pfam PF00005 ABC transporter 19 165 2.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS01530 2622b295d2701dfdbc7aac01e3d9ea5b 231 Gene3D G3DSA:3.40.50.300 1 217 5.7E-54 T 29-03-2018 CXR48_RS01530 2622b295d2701dfdbc7aac01e3d9ea5b 231 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS01530 2622b295d2701dfdbc7aac01e3d9ea5b 231 SUPERFAMILY SSF52540 3 215 2.15E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01530 2622b295d2701dfdbc7aac01e3d9ea5b 231 SMART SM00382 28 215 1.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 SUPERFAMILY SSF54184 598 654 2.35E-12 T 29-03-2018 CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 SUPERFAMILY SSF56601 191 590 2.05E-94 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 SMART SM00740 595 655 8.4E-8 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 SMART SM00740 656 712 0.52 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 Gene3D G3DSA:3.40.710.10 242 607 2.2E-88 T 29-03-2018 CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 SUPERFAMILY SSF54184 656 711 3.79E-12 T 29-03-2018 CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 SUPERFAMILY SSF56519 56 240 2.88E-46 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 Gene3D G3DSA:3.90.1310.10 24 241 6.8E-40 T 29-03-2018 CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 Pfam PF03793 PASTA domain 600 653 4.0E-6 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 Pfam PF03793 PASTA domain 657 709 8.0E-8 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 Pfam PF00905 Penicillin binding protein transpeptidase domain 267 567 5.2E-89 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS07560 aa7f352526ec067427a085a4abbc2e54 714 Pfam PF03717 Penicillin-binding Protein dimerisation domain 58 223 1.7E-23 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS03650 798d0e8796dc2343a8a845768d28b48b 376 SUPERFAMILY SSF52540 72 354 2.96E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03650 798d0e8796dc2343a8a845768d28b48b 376 Pfam PF00271 Helicase conserved C-terminal domain 230 335 5.0E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS03650 798d0e8796dc2343a8a845768d28b48b 376 SMART SM00490 255 335 1.8E-21 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS03650 798d0e8796dc2343a8a845768d28b48b 376 SMART SM00487 23 220 2.2E-50 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS03650 798d0e8796dc2343a8a845768d28b48b 376 Pfam PF00270 DEAD/DEAH box helicase 28 192 3.5E-45 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CXR48_RS03650 798d0e8796dc2343a8a845768d28b48b 376 Gene3D G3DSA:3.40.50.300 213 368 9.5E-35 T 29-03-2018 CXR48_RS03650 798d0e8796dc2343a8a845768d28b48b 376 Gene3D G3DSA:3.40.50.300 2 212 3.4E-50 T 29-03-2018 CXR48_RS09980 e317ffb54ce8c9735c9d2df6e0e33c75 144 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 4 127 37.367 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CXR48_RS09980 e317ffb54ce8c9735c9d2df6e0e33c75 144 Gene3D G3DSA:2.170.150.20 1 143 2.7E-54 T 29-03-2018 CXR48_RS09980 e317ffb54ce8c9735c9d2df6e0e33c75 144 SUPERFAMILY SSF51316 3 143 2.41E-60 T 29-03-2018 IPR011057 Mss4-like CXR48_RS09980 e317ffb54ce8c9735c9d2df6e0e33c75 144 Pfam PF01641 SelR domain 10 126 4.1E-49 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CXR48_RS09980 e317ffb54ce8c9735c9d2df6e0e33c75 144 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 4 135 1.1E-66 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CXR48_RS13990 5995678d8f8ba39c70647d834737f96a 103 SUPERFAMILY SSF52821 2 99 3.27E-29 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS13990 5995678d8f8ba39c70647d834737f96a 103 Gene3D G3DSA:3.40.250.10 1 103 3.6E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS13990 5995678d8f8ba39c70647d834737f96a 103 SMART SM00450 7 101 9.2E-21 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS13990 5995678d8f8ba39c70647d834737f96a 103 Pfam PF00581 Rhodanese-like domain 10 96 6.7E-14 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 Pfam PF02881 SRP54-type protein, helical bundle domain 33 99 1.6E-15 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 2.0E-80 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 SMART SM00963 22 103 1.3E-27 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 Gene3D G3DSA:1.20.120.140 22 116 1.5E-23 T 29-03-2018 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 Gene3D G3DSA:1.20.120.140 1 21 0.13 T 29-03-2018 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 SMART SM00382 119 320 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 320 1.2E-118 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 SUPERFAMILY SSF52540 120 320 2.08E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 SMART SM00962 120 321 1.2E-120 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 SUPERFAMILY SSF47364 18 96 4.19E-22 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 Gene3D G3DSA:3.40.50.300 117 322 2.5E-42 T 29-03-2018 CXR48_RS07950 119de8531d4c9e201aa98b5025304aa1 329 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 65.989 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CXR48_RS08615 93a499aaf082abf4f8af9f8c704f4c2c 235 Pfam PF05908 Poly-gamma-glutamate hydrolase 36 224 1.2E-71 T 29-03-2018 IPR008585 Poly-gamma-glutamate hydrolase CXR48_RS07030 c7f5f93cf3b0ca53516459a76cb4520f 268 Gene3D G3DSA:3.30.70.100 175 263 2.3E-10 T 29-03-2018 CXR48_RS07030 c7f5f93cf3b0ca53516459a76cb4520f 268 Gene3D G3DSA:2.30.30.60 126 174 1.0E-13 T 29-03-2018 CXR48_RS07030 c7f5f93cf3b0ca53516459a76cb4520f 268 SUPERFAMILY SSF82689 174 260 2.22E-8 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CXR48_RS07030 c7f5f93cf3b0ca53516459a76cb4520f 268 Pfam PF00924 Mechanosensitive ion channel 70 261 2.2E-47 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CXR48_RS07030 c7f5f93cf3b0ca53516459a76cb4520f 268 SUPERFAMILY SSF50182 111 170 4.25E-15 T 29-03-2018 IPR010920 LSM domain CXR48_RS07030 c7f5f93cf3b0ca53516459a76cb4520f 268 SUPERFAMILY SSF82861 21 109 3.01E-14 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01270 Histone deacetylase superfamily signature 129 152 2.8E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01270 Histone deacetylase superfamily signature 248 258 2.8E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01270 Histone deacetylase superfamily signature 162 177 2.8E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 Pfam PF00850 Histone deacetylase domain 21 315 1.9E-74 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 Gene3D G3DSA:3.40.800.20 1 381 1.0E-91 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 SUPERFAMILY SSF52768 5 372 7.19E-106 T 29-03-2018 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 312 331 6.5E-57 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 6.5E-57 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 106 119 6.5E-57 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 273 289 6.5E-57 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 85 99 6.5E-57 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 349 368 6.5E-57 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CXR48_RS13780 d38b164fe09c9bc368df3c6592a9cf58 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 332 348 6.5E-57 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CXR48_RS14020 ddb5978f2f270674179a3edc6479ef2c 646 PIRSF PIRSF018968 1 646 1.4E-148 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2299 2315 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF14765 Polyketide synthase dehydratase 1292 1515 7.6E-15 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SMART SM00823 Phosphopantetheine attachment site 544 614 2.0E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SMART SM00823 Phosphopantetheine attachment site 2629 2700 0.0048 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SMART SM00823 Phosphopantetheine attachment site 2019 2090 9.3E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SMART SM00825 Beta-ketoacyl synthase 667 1085 4.0E-199 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SMART SM00825 Beta-ketoacyl synthase 2142 2575 3.7E-189 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF51735 274 502 7.42E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 ProSitePatterns PS00012 Phosphopantetheine attachment site. 570 585 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:3.40.47.10 2401 2573 8.9E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:3.40.47.10 922 1083 6.1E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF53901 1061 1081 5.13E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF53901 662 1025 5.13E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF47336 2623 2703 3.14E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2394 2516 2.9E-39 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 915 1030 8.2E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF47336 2124 2154 4.71E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF47336 2015 2091 4.71E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF53901 2137 2509 1.34E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF53901 2551 2570 1.34E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF00550 Phosphopantetheine attachment site 2020 2086 1.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF00550 Phosphopantetheine attachment site 546 609 7.7E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF00550 Phosphopantetheine attachment site 2630 2696 5.0E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:1.10.1200.10 2619 2705 2.0E-11 T 29-03-2018 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 665 907 1.4E-83 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2140 2386 4.5E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF08659 KR domain 1750 1933 4.2E-51 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF08659 KR domain 277 457 8.3E-51 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:3.10.129.10 1264 1379 0.002 T 29-03-2018 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:3.40.50.720 270 521 3.4E-41 T 29-03-2018 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:3.40.50.720 1742 2002 5.8E-42 T 29-03-2018 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF51735 1748 1979 9.85E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2520 2621 8.0E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1037 1150 5.0E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:1.10.1200.10 2003 2100 1.5E-13 T 29-03-2018 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SUPERFAMILY SSF47336 542 615 1.06E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SMART SM01294 2020 2086 3.9E-4 T 29-03-2018 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:3.40.47.10 2132 2398 5.1E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:3.40.47.10 657 919 3.2E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 Gene3D G3DSA:1.10.1200.10 522 618 1.2E-12 T 29-03-2018 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 277 458 1.1E-41 T 29-03-2018 CXR48_RS07235 ce67919ede6dd49052fa55785521daac 2898 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1750 1935 8.2E-42 T 29-03-2018 CXR48_RS01435 ecb0b3c54e6025c2deb10469199a00a7 583 Pfam PF09423 PhoD-like phosphatase 175 512 7.0E-120 T 29-03-2018 IPR018946 Alkaline phosphatase D-related CXR48_RS01435 ecb0b3c54e6025c2deb10469199a00a7 583 Gene3D G3DSA:2.60.40.380 64 166 7.3E-9 T 29-03-2018 CXR48_RS01435 ecb0b3c54e6025c2deb10469199a00a7 583 SUPERFAMILY SSF56300 168 515 1.14E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS01435 ecb0b3c54e6025c2deb10469199a00a7 583 Gene3D G3DSA:3.60.21.10 171 576 6.1E-53 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS01435 ecb0b3c54e6025c2deb10469199a00a7 583 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 67 162 7.7E-33 T 29-03-2018 IPR032093 Phospholipase D, N-terminal CXR48_RS07095 0bae29f657a102c49a11cf6741c69cd8 397 SMART SM01066 57 132 0.0052 T 29-03-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 CXR48_RS07095 0bae29f657a102c49a11cf6741c69cd8 397 Pfam PF12704 MacB-like periplasmic core domain 21 238 1.8E-30 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CXR48_RS07095 0bae29f657a102c49a11cf6741c69cd8 397 Pfam PF02687 FtsX-like permease family 303 390 1.8E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CXR48_RS03220 5ae2757fa307e08de2eedf0e9c542dc4 735 Pfam PF01841 Transglutaminase-like superfamily 426 549 2.2E-28 T 29-03-2018 IPR002931 Transglutaminase-like CXR48_RS03220 5ae2757fa307e08de2eedf0e9c542dc4 735 Gene3D G3DSA:3.90.260.10 425 582 1.5E-28 T 29-03-2018 IPR002931 Transglutaminase-like CXR48_RS03220 5ae2757fa307e08de2eedf0e9c542dc4 735 Pfam PF13559 Domain of unknown function (DUF4129) 663 713 5.8E-7 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 CXR48_RS03220 5ae2757fa307e08de2eedf0e9c542dc4 735 SUPERFAMILY SSF54001 407 573 2.62E-46 T 29-03-2018 CXR48_RS03220 5ae2757fa307e08de2eedf0e9c542dc4 735 SMART SM00460 476 551 9.1E-26 T 29-03-2018 IPR002931 Transglutaminase-like CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 SUPERFAMILY SSF53067 1 194 1.77E-73 T 29-03-2018 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 Gene3D G3DSA:3.30.420.40 195 395 5.0E-80 T 29-03-2018 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 PIRSF PIRSF000722 1 395 1.6E-155 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 PRINTS PR00471 Acetate kinase family signature 299 312 2.0E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 PRINTS PR00471 Acetate kinase family signature 202 223 2.0E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 PRINTS PR00471 Acetate kinase family signature 321 337 2.0E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 PRINTS PR00471 Acetate kinase family signature 375 387 2.0E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 PRINTS PR00471 Acetate kinase family signature 4 15 2.0E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 PRINTS PR00471 Acetate kinase family signature 172 185 2.0E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 SUPERFAMILY SSF53067 157 393 2.59E-95 T 29-03-2018 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 Pfam PF00871 Acetokinase family 3 388 3.3E-179 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 TIGRFAM TIGR00016 ackA: acetate kinase 2 394 1.5E-184 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 Gene3D G3DSA:3.30.420.40 3 194 2.2E-81 T 29-03-2018 CXR48_RS13585 81da8ad9949772618db54bcc1e89bad4 395 Hamap MF_00020 Acetate kinase [ackA]. 1 395 199.323 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS18255 1893d19723976a9c68b428d7b3d8afe8 363 Gene3D G3DSA:3.30.470.10 1 175 8.3E-68 T 29-03-2018 CXR48_RS18255 1893d19723976a9c68b428d7b3d8afe8 363 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 44 356 6.2E-123 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CXR48_RS18255 1893d19723976a9c68b428d7b3d8afe8 363 ProSitePatterns PS00770 Aminotransferases class-IV signature. 233 262 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS18255 1893d19723976a9c68b428d7b3d8afe8 363 Pfam PF01063 Amino-transferase class IV 70 312 1.1E-34 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS18255 1893d19723976a9c68b428d7b3d8afe8 363 Gene3D G3DSA:3.20.10.10 176 339 1.5E-50 T 29-03-2018 CXR48_RS18255 1893d19723976a9c68b428d7b3d8afe8 363 SUPERFAMILY SSF56752 4 353 6.02E-115 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS18255 1893d19723976a9c68b428d7b3d8afe8 363 PIRSF PIRSF006468 1 358 1.5E-135 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CXR48_RS02450 60a58a3297be39d0410c37ecb9b90102 335 Gene3D G3DSA:1.10.1240.30 5 83 3.4E-29 T 29-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 CXR48_RS02450 60a58a3297be39d0410c37ecb9b90102 335 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 9 83 2.3E-30 T 29-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 CXR48_RS02450 60a58a3297be39d0410c37ecb9b90102 335 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 146 333 1.1E-51 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS02450 60a58a3297be39d0410c37ecb9b90102 335 Gene3D G3DSA:3.60.40.10 85 335 4.4E-32 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS02450 60a58a3297be39d0410c37ecb9b90102 335 SUPERFAMILY SSF81606 127 332 4.32E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS02450 60a58a3297be39d0410c37ecb9b90102 335 SMART SM00331 119 333 8.3E-74 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS02450 60a58a3297be39d0410c37ecb9b90102 335 SUPERFAMILY SSF101215 2 84 3.27E-30 T 29-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 CXR48_RS02450 60a58a3297be39d0410c37ecb9b90102 335 ProDom PD685490 RSBU REGULATOR SIGMA REGULATION FACTOR B PHOSPHATASE SIGMAB INDIRECT SIGMA-B 5 91 5.0E-43 T 29-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 CXR48_RS15590 c4791583eb8057295b8529f6b59cd65a 336 Gene3D G3DSA:1.10.3470.10 3 336 2.9E-70 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS15590 c4791583eb8057295b8529f6b59cd65a 336 Pfam PF01032 FecCD transport family 18 334 2.3E-97 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CXR48_RS15590 c4791583eb8057295b8529f6b59cd65a 336 SUPERFAMILY SSF81345 6 334 1.44E-87 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS12845 d54f64f09a0b84780562c78b35b1760b 285 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 230 237 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CXR48_RS12845 d54f64f09a0b84780562c78b35b1760b 285 Gene3D G3DSA:3.30.70.260 194 285 1.3E-22 T 29-03-2018 CXR48_RS12845 d54f64f09a0b84780562c78b35b1760b 285 SUPERFAMILY SSF55021 193 281 4.93E-22 T 29-03-2018 CXR48_RS12845 d54f64f09a0b84780562c78b35b1760b 285 PIRSF PIRSF001500 1 285 6.6E-70 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CXR48_RS12845 d54f64f09a0b84780562c78b35b1760b 285 SUPERFAMILY SSF53850 1 185 3.62E-52 T 29-03-2018 CXR48_RS12845 d54f64f09a0b84780562c78b35b1760b 285 Gene3D G3DSA:3.40.190.10 1 92 1.8E-29 T 29-03-2018 CXR48_RS12845 d54f64f09a0b84780562c78b35b1760b 285 Pfam PF00800 Prephenate dehydratase 3 185 2.7E-56 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CXR48_RS12845 d54f64f09a0b84780562c78b35b1760b 285 Gene3D G3DSA:3.40.190.10 93 172 2.7E-24 T 29-03-2018 CXR48_RS12845 d54f64f09a0b84780562c78b35b1760b 285 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 159 181 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CXR48_RS15740 3e98c5c26557ef0960aa14ebb2143d10 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CXR48_RS15740 3e98c5c26557ef0960aa14ebb2143d10 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 68 6.0E-31 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CXR48_RS15740 3e98c5c26557ef0960aa14ebb2143d10 68 SUPERFAMILY SSF55008 2 68 2.88E-21 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CXR48_RS15740 3e98c5c26557ef0960aa14ebb2143d10 68 Pfam PF00403 Heavy-metal-associated domain 5 66 1.5E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CXR48_RS15740 3e98c5c26557ef0960aa14ebb2143d10 68 Gene3D G3DSA:3.30.70.100 1 68 1.3E-22 T 29-03-2018 CXR48_RS15740 3e98c5c26557ef0960aa14ebb2143d10 68 PRINTS PR00944 Copper ion binding protein signature 54 67 8.7E-9 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CXR48_RS15740 3e98c5c26557ef0960aa14ebb2143d10 68 PRINTS PR00944 Copper ion binding protein signature 15 28 8.7E-9 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CXR48_RS15740 3e98c5c26557ef0960aa14ebb2143d10 68 PRINTS PR00944 Copper ion binding protein signature 3 15 8.7E-9 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CXR48_RS15740 3e98c5c26557ef0960aa14ebb2143d10 68 PRINTS PR00944 Copper ion binding protein signature 28 41 8.7E-9 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Gene3D G3DSA:1.10.10.60 606 684 2.3E-16 T 29-03-2018 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Pfam PF00158 Sigma-54 interaction domain 368 535 1.5E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 SUPERFAMILY SSF51735 1 98 4.1E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 SUPERFAMILY SSF52540 367 601 3.75E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 SUPERFAMILY SSF46689 631 683 1.43E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 647 664 5.3E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 664 684 5.3E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Gene3D G3DSA:1.10.8.60 542 605 1.5E-22 T 29-03-2018 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Pfam PF02954 Bacterial regulatory protein, Fis family 641 681 4.4E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 392 405 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Pfam PF00989 PAS fold 120 218 5.0E-16 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Pfam PF00989 PAS fold 237 339 5.6E-14 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 SMART SM00382 388 532 8.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Gene3D G3DSA:3.30.450.20 229 359 1.1E-15 T 29-03-2018 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Gene3D G3DSA:3.30.450.20 110 228 1.5E-19 T 29-03-2018 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 455 470 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 SUPERFAMILY SSF55785 104 215 6.98E-17 T 29-03-2018 IPR000014 PAS domain CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 582 591 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 SMART SM00091 117 183 4.4E-10 T 29-03-2018 IPR000014 PAS domain CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 SMART SM00091 236 301 1.9E-5 T 29-03-2018 IPR000014 PAS domain CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 SUPERFAMILY SSF55785 217 336 1.92E-14 T 29-03-2018 IPR000014 PAS domain CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Gene3D G3DSA:3.40.50.300 361 540 9.1E-29 T 29-03-2018 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 Gene3D G3DSA:3.40.50.720 1 109 1.2E-10 T 29-03-2018 CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 235 349 2.8E-17 T 29-03-2018 IPR000014 PAS domain CXR48_RS11545 f4a10b41273b635394f583b71ba09659 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 119 227 2.8E-12 T 29-03-2018 IPR000014 PAS domain CXR48_RS02610 2644789d13cccae23a09dbe2aa7c9c02 375 SUPERFAMILY SSF56281 124 370 7.45E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS02610 2644789d13cccae23a09dbe2aa7c9c02 375 SUPERFAMILY SSF52821 2 110 1.7E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02610 2644789d13cccae23a09dbe2aa7c9c02 375 Pfam PF00581 Rhodanese-like domain 7 105 1.5E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02610 2644789d13cccae23a09dbe2aa7c9c02 375 Gene3D G3DSA:3.60.15.10 118 371 5.2E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS02610 2644789d13cccae23a09dbe2aa7c9c02 375 SMART SM00450 7 109 7.5E-13 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02610 2644789d13cccae23a09dbe2aa7c9c02 375 SMART SM00849 130 294 2.6E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS02610 2644789d13cccae23a09dbe2aa7c9c02 375 Gene3D G3DSA:3.40.250.10 1 117 2.0E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02610 2644789d13cccae23a09dbe2aa7c9c02 375 Pfam PF00753 Metallo-beta-lactamase superfamily 130 275 1.1E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SMART SM00823 Phosphopantetheine attachment site 2004 2073 0.002 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SMART SM00823 Phosphopantetheine attachment site 973 1042 0.0018 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SMART SM00823 Phosphopantetheine attachment site 3032 3100 4.3E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF52777 5 206 1.33E-41 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF47336 965 1038 6.67E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 ProSitePatterns PS00012 Phosphopantetheine attachment site. 997 1012 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF56801 1460 2016 2.88E-155 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF52777 2083 2267 6.67E-43 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2671 2682 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1641 1652 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF52777 1222 1467 5.0E-64 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF52777 3301 3560 3.11E-28 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.40.50.980 1492 1646 4.0E-46 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.40.50.980 461 613 2.6E-46 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.40.50.980 2524 2676 3.6E-49 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:2.30.38.10 777 856 1.3E-19 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:2.30.38.10 1811 1891 1.3E-22 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:2.30.38.10 2837 2914 7.6E-22 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00550 Phosphopantetheine attachment site 3034 3095 4.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00550 Phosphopantetheine attachment site 2006 2067 3.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00550 Phosphopantetheine attachment site 975 1036 2.6E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF47336 1996 2069 5.33E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 890 1.7E-123 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1522 1925 3.7E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2553 2948 4.5E-133 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF56801 430 985 2.35E-144 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF52777 1053 1235 1.1E-42 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00501 AMP-binding enzyme 470 866 3.4E-92 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00501 AMP-binding enzyme 1501 1901 1.3E-100 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00501 AMP-binding enzyme 2534 2924 5.3E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF52777 191 452 6.45E-45 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00668 Condensation domain 2086 2511 1.6E-137 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00668 Condensation domain 8 451 7.5E-120 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00668 Condensation domain 1056 1479 1.1E-133 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF00668 Condensation domain 3109 3577 6.4E-99 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF47336 3025 3096 7.85E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 PRINTS PR00154 AMP-binding signature 2666 2677 9.1E-5 T 29-03-2018 IPR020459 AMP-binding CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 PRINTS PR00154 AMP-binding signature 2678 2686 9.1E-5 T 29-03-2018 IPR020459 AMP-binding CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:1.10.1200.10 3036 3101 3.7E-21 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3056 3071 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3427 3584 8.3E-42 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.40.50.980 1647 1810 1.5E-37 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.40.50.980 614 772 5.5E-28 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.40.50.980 2677 2836 1.2E-34 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:1.10.1200.10 979 1038 5.5E-21 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:1.10.1200.10 2009 2070 2.1E-21 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF56801 2490 3044 1.57E-153 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF52777 3106 3287 1.11E-33 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 ProSitePatterns PS00455 Putative AMP-binding domain signature. 608 619 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.30.559.10 1039 1237 2.3E-40 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.30.559.10 3 213 4.9E-32 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.30.559.10 3102 3318 4.0E-30 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.30.559.10 2071 2269 2.1E-42 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF13193 AMP-binding enzyme C-terminal domain 1909 1978 3.0E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 947 7.9E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Pfam PF13193 AMP-binding enzyme C-terminal domain 2932 3005 9.4E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.30.300.30 2919 3035 4.9E-37 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.30.300.30 1896 2008 5.0E-36 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 Gene3D G3DSA:3.30.300.30 861 978 3.0E-39 T 29-03-2018 CXR48_RS09235 155dd488181b3fb58ebc47c5f5f5db15 3591 SUPERFAMILY SSF52777 2254 2495 1.07E-66 T 29-03-2018 CXR48_RS19335 1b0820a40dbe464ee6933ca64a284dac 185 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 88 167 7.2E-36 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS19335 1b0820a40dbe464ee6933ca64a284dac 185 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 89 168 1.6E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS19335 1b0820a40dbe464ee6933ca64a284dac 185 SUPERFAMILY SSF53155 6 85 4.12E-10 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS19335 1b0820a40dbe464ee6933ca64a284dac 185 SUPERFAMILY SSF46767 87 168 9.29E-32 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS19335 1b0820a40dbe464ee6933ca64a284dac 185 Gene3D G3DSA:3.30.160.70 1 84 7.9E-12 T 29-03-2018 CXR48_RS19335 1b0820a40dbe464ee6933ca64a284dac 185 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 138 144 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS19335 1b0820a40dbe464ee6933ca64a284dac 185 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 6 85 2.6E-7 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS19335 1b0820a40dbe464ee6933ca64a284dac 185 Gene3D G3DSA:1.10.10.10 85 170 8.0E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.0E-40 T 29-03-2018 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.0E-40 T 29-03-2018 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.0E-40 T 29-03-2018 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.0E-40 T 29-03-2018 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 Gene3D G3DSA:3.40.50.261 120 299 1.4E-55 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 5.6E-150 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 PIRSF PIRSF001553 1 291 1.1E-134 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 SUPERFAMILY SSF51735 1 122 2.91E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 SUPERFAMILY SSF52210 123 287 7.59E-55 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.976 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 SMART SM00881 4 100 2.8E-36 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 Gene3D G3DSA:3.40.50.720 1 119 2.9E-46 T 29-03-2018 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 Pfam PF02629 CoA binding domain 6 99 9.1E-32 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CXR48_RS08025 3886bda3d8e3315621f7b12e020cba4d 300 Pfam PF00549 CoA-ligase 151 267 3.1E-19 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 5 228 2.5E-115 T 29-03-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 SUPERFAMILY SSF88659 139 225 1.55E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 PRINTS PR00046 Major sigma-70 factor signature 212 223 7.1E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 PRINTS PR00046 Major sigma-70 factor signature 176 188 7.1E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 PRINTS PR00046 Major sigma-70 factor signature 78 91 7.1E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 PRINTS PR00046 Major sigma-70 factor signature 197 212 7.1E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 Gene3D G3DSA:1.10.1270.10 143 238 5.9E-22 T 29-03-2018 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 223 6.1E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 SUPERFAMILY SSF88946 9 120 4.45E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 Gene3D G3DSA:1.10.601.10 20 122 5.8E-28 T 29-03-2018 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 Pfam PF04542 Sigma-70 region 2 54 123 3.1E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 197 223 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 Pfam PF04545 Sigma-70, region 4 173 223 1.5E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12380 04e81486bc79bcf507937da2e0336d80 240 PIRSF PIRSF000770 1 240 4.7E-94 T 29-03-2018 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 SUPERFAMILY SSF52374 4 157 1.83E-42 T 29-03-2018 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 Pfam PF01467 Cytidylyltransferase-like 7 134 1.6E-19 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 Gene3D G3DSA:3.40.50.620 2 159 8.1E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 1.3E-61 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 4.4E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 4.4E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 4.4E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 4.4E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 4.4E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 64 3.3E-18 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CXR48_RS07490 25204472837215d1a52dbe2d37a7c2d0 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 35.526 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CXR48_RS19175 68a1064b3b42089e5d40260c1bfc0d21 519 Gene3D G3DSA:2.115.10.20 26 372 4.6E-79 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS19175 68a1064b3b42089e5d40260c1bfc0d21 519 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 50 358 5.1E-82 T 29-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CXR48_RS19175 68a1064b3b42089e5d40260c1bfc0d21 519 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 362 511 1.6E-27 T 29-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CXR48_RS19175 68a1064b3b42089e5d40260c1bfc0d21 519 SUPERFAMILY SSF49899 359 517 8.7E-28 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CXR48_RS19175 68a1064b3b42089e5d40260c1bfc0d21 519 SUPERFAMILY SSF75005 43 360 2.42E-84 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS19175 68a1064b3b42089e5d40260c1bfc0d21 519 SMART SM00640 50 478 7.8E-122 T 29-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CXR48_RS19175 68a1064b3b42089e5d40260c1bfc0d21 519 Gene3D G3DSA:2.60.120.560 373 519 2.6E-32 T 29-03-2018 CXR48_RS00220 e213e8ccefd8745262c0efa12c9a2aa9 329 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 17 199 3.1E-67 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS00220 e213e8ccefd8745262c0efa12c9a2aa9 329 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 240 325 4.3E-7 T 29-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS00220 e213e8ccefd8745262c0efa12c9a2aa9 329 SUPERFAMILY SSF52540 11 198 4.84E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00220 e213e8ccefd8745262c0efa12c9a2aa9 329 Gene3D G3DSA:1.20.272.10 208 329 3.7E-22 T 29-03-2018 CXR48_RS00220 e213e8ccefd8745262c0efa12c9a2aa9 329 Pfam PF13177 DNA polymerase III, delta subunit 12 169 8.7E-60 T 29-03-2018 CXR48_RS00220 e213e8ccefd8745262c0efa12c9a2aa9 329 Gene3D G3DSA:3.40.50.300 15 167 3.2E-31 T 29-03-2018 CXR48_RS12030 a278c04bd3b010139dea4a15080fd8c5 100 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 1 98 3.0E-32 T 29-03-2018 IPR020506 Uncharacterised protein family YqfZ CXR48_RS12030 a278c04bd3b010139dea4a15080fd8c5 100 SMART SM00257 49 96 1.4E-5 T 29-03-2018 IPR018392 LysM domain CXR48_RS12030 a278c04bd3b010139dea4a15080fd8c5 100 Gene3D G3DSA:3.10.350.10 36 100 1.4E-8 T 29-03-2018 CXR48_RS18820 733a54bbcc87df2252cc5510a8e17ff0 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 9.0E-102 T 29-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CXR48_RS18820 733a54bbcc87df2252cc5510a8e17ff0 187 Gene3D G3DSA:3.30.1020.10 155 183 2.6E-6 T 29-03-2018 CXR48_RS18820 733a54bbcc87df2252cc5510a8e17ff0 187 SUPERFAMILY SSF52833 1 187 3.32E-53 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS18820 733a54bbcc87df2252cc5510a8e17ff0 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 1.8E-4 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CXR48_RS18820 733a54bbcc87df2252cc5510a8e17ff0 187 PIRSF PIRSF000239 1 187 1.3E-48 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CXR48_RS18820 733a54bbcc87df2252cc5510a8e17ff0 187 Pfam PF00578 AhpC/TSA family 4 133 7.7E-32 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CXR48_RS18820 733a54bbcc87df2252cc5510a8e17ff0 187 Gene3D G3DSA:3.40.30.10 3 154 1.1E-30 T 29-03-2018 CXR48_RS09775 4c34ab41a179a9de8c70cad021cd4e3a 92 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 4 50 1.5E-10 T 29-03-2018 IPR022453 Zinc finger, MqsA-type CXR48_RS09775 4c34ab41a179a9de8c70cad021cd4e3a 92 Pfam PF14122 YokU-like protein, putative antitoxin 4 89 4.2E-41 T 29-03-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU CXR48_RS09775 4c34ab41a179a9de8c70cad021cd4e3a 92 TIGRFAM TIGR03829 YokU_near_AblA: uncharacterized protein, YokU family 4 91 7.1E-44 T 29-03-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU CXR48_RS18695 ffd4d8cc90f1313e4c63b83f06713f84 289 Pfam PF01261 Xylose isomerase-like TIM barrel 23 241 1.9E-38 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS18695 ffd4d8cc90f1313e4c63b83f06713f84 289 SUPERFAMILY SSF51658 1 281 1.57E-54 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS18695 ffd4d8cc90f1313e4c63b83f06713f84 289 Gene3D G3DSA:3.20.20.150 1 289 1.4E-46 T 29-03-2018 CXR48_RS11395 526765a607f021beb98832a24b5a61e2 176 SUPERFAMILY SSF50104 125 172 3.85E-7 T 29-03-2018 IPR008991 Translation protein SH3-like domain CXR48_RS11395 526765a607f021beb98832a24b5a61e2 176 SUPERFAMILY SSF82679 1 114 6.54E-18 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CXR48_RS11395 526765a607f021beb98832a24b5a61e2 176 Gene3D G3DSA:3.30.70.940 1 114 3.5E-22 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CXR48_RS11395 526765a607f021beb98832a24b5a61e2 176 Pfam PF02357 Transcription termination factor nusG 1 104 1.6E-15 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CXR48_RS11395 526765a607f021beb98832a24b5a61e2 176 SMART SM00738 1 111 4.0E-6 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CXR48_RS11395 526765a607f021beb98832a24b5a61e2 176 PRINTS PR00338 Transcription termination factor NUSG signature 134 149 8.5E-5 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CXR48_RS11395 526765a607f021beb98832a24b5a61e2 176 PRINTS PR00338 Transcription termination factor NUSG signature 50 62 8.5E-5 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CXR48_RS11395 526765a607f021beb98832a24b5a61e2 176 PRINTS PR00338 Transcription termination factor NUSG signature 152 168 8.5E-5 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CXR48_RS11395 526765a607f021beb98832a24b5a61e2 176 Gene3D G3DSA:2.30.30.30 120 175 6.0E-7 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 Gene3D G3DSA:1.20.1270.10 502 588 3.3E-21 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 Gene3D G3DSA:2.60.34.10 360 501 3.1E-67 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 SUPERFAMILY SSF53067 2 157 9.5E-58 T 29-03-2018 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 SUPERFAMILY SSF100920 354 510 5.49E-62 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 3.9E-286 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 Gene3D G3DSA:3.30.420.40 171 331 9.2E-50 T 29-03-2018 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 605 37.139 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 SUPERFAMILY SSF100934 477 575 1.44E-12 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.1E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 PRINTS PR00301 70kDa heat shock protein signature 304 320 2.1E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 PRINTS PR00301 70kDa heat shock protein signature 439 455 2.1E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 PRINTS PR00301 70kDa heat shock protein signature 358 377 2.1E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.1E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 PRINTS PR00301 70kDa heat shock protein signature 112 132 2.1E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 PRINTS PR00301 70kDa heat shock protein signature 335 355 2.1E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 PRINTS PR00301 70kDa heat shock protein signature 53 61 2.1E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 PRINTS PR00301 70kDa heat shock protein signature 172 182 2.1E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 Pfam PF00012 Hsp70 protein 76 573 1.6E-222 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 Gene3D G3DSA:3.30.420.40 1 170 2.8E-68 T 29-03-2018 CXR48_RS12235 41ad03b4a264a1aa8ddf87d94902059a 612 SUPERFAMILY SSF53067 160 351 2.3E-67 T 29-03-2018 CXR48_RS06195 8f2cf2f91484ef0bba12aa6484161f62 112 Gene3D G3DSA:1.10.260.40 1 109 2.1E-25 T 29-03-2018 CXR48_RS06195 8f2cf2f91484ef0bba12aa6484161f62 112 Pfam PF12844 Helix-turn-helix domain 3 62 1.6E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS06195 8f2cf2f91484ef0bba12aa6484161f62 112 SMART SM00530 5 58 2.2E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS06195 8f2cf2f91484ef0bba12aa6484161f62 112 SUPERFAMILY SSF47413 2 65 1.15E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS04205 1c7a145d8be1a2e93e1893d64333c806 573 SUPERFAMILY SSF52540 324 570 5.33E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04205 1c7a145d8be1a2e93e1893d64333c806 573 Pfam PF00664 ABC transporter transmembrane region 12 282 1.2E-46 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04205 1c7a145d8be1a2e93e1893d64333c806 573 Gene3D G3DSA:3.40.50.300 322 573 1.0E-79 T 29-03-2018 CXR48_RS04205 1c7a145d8be1a2e93e1893d64333c806 573 Pfam PF00005 ABC transporter 351 500 7.9E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS04205 1c7a145d8be1a2e93e1893d64333c806 573 Gene3D G3DSA:1.20.1560.10 1 321 1.1E-69 T 29-03-2018 CXR48_RS04205 1c7a145d8be1a2e93e1893d64333c806 573 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS04205 1c7a145d8be1a2e93e1893d64333c806 573 SUPERFAMILY SSF90123 2 320 1.44E-80 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04205 1c7a145d8be1a2e93e1893d64333c806 573 SMART SM00382 360 546 1.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Gene3D G3DSA:1.10.10.10 1 71 3.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Gene3D G3DSA:1.10.10.10 91 157 7.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Gene3D G3DSA:3.40.930.10 512 650 2.1E-30 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 517 649 1.1E-28 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 SUPERFAMILY SSF55804 512 649 7.72E-30 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Pfam PF08279 HTH domain 7 65 5.8E-7 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Gene3D G3DSA:3.40.50.2300 408 498 9.1E-17 T 29-03-2018 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 557 573 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 SUPERFAMILY SSF63520 301 402 5.36E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 SUPERFAMILY SSF63520 193 285 6.54E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Pfam PF00874 PRD domain 199 283 1.4E-14 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Pfam PF00874 PRD domain 311 399 3.4E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Pfam PF05043 Mga helix-turn-helix domain 103 164 9.0E-8 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 SUPERFAMILY SSF52794 410 489 8.37E-8 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Gene3D G3DSA:1.10.1790.10 288 403 1.5E-25 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS12460 076b7948d7c8bbebd73486e7fa772464 650 Gene3D G3DSA:1.10.1790.10 166 287 4.4E-14 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS04770 4b338d2495e6427c7c5eddcf78e9fe74 119 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 113 2.0E-21 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CXR48_RS04770 4b338d2495e6427c7c5eddcf78e9fe74 119 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 118 16.493 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CXR48_RS04770 4b338d2495e6427c7c5eddcf78e9fe74 119 TIGRFAM TIGR00494 crcB: protein CrcB 6 116 2.5E-30 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CXR48_RS16380 cbae4ffc132453e2fd95db6dca901108 295 PIRSF PIRSF005052 9 294 6.9E-109 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CXR48_RS16380 cbae4ffc132453e2fd95db6dca901108 295 Gene3D G3DSA:3.40.50.300 2 169 2.0E-6 T 29-03-2018 CXR48_RS16380 cbae4ffc132453e2fd95db6dca901108 295 Pfam PF03668 P-loop ATPase protein family 9 292 4.0E-143 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CXR48_RS16380 cbae4ffc132453e2fd95db6dca901108 295 SUPERFAMILY SSF52540 11 166 2.77E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16380 cbae4ffc132453e2fd95db6dca901108 295 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 9 291 42.153 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CXR48_RS07875 4299270bfb3c29351df3970aacd427ab 214 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 22 127 8.4E-22 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CXR48_RS07875 4299270bfb3c29351df3970aacd427ab 214 SMART SM00983 142 208 7.6E-26 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CXR48_RS07875 4299270bfb3c29351df3970aacd427ab 214 Gene3D G3DSA:2.60.120.320 120 214 2.7E-21 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CXR48_RS07875 4299270bfb3c29351df3970aacd427ab 214 SUPERFAMILY SSF63862 134 211 5.89E-14 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CXR48_RS07875 4299270bfb3c29351df3970aacd427ab 214 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 4 210 9.2E-67 T 29-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CXR48_RS07875 4299270bfb3c29351df3970aacd427ab 214 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 144 207 1.1E-15 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CXR48_RS07875 4299270bfb3c29351df3970aacd427ab 214 Gene3D G3DSA:3.40.50.10240 1 119 3.9E-26 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CXR48_RS07875 4299270bfb3c29351df3970aacd427ab 214 SUPERFAMILY SSF63999 1 131 2.22E-35 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 55 501 1.4E-147 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 Gene3D G3DSA:1.10.287.70 570 637 2.9E-16 T 29-03-2018 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 274 295 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 457 478 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 335 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 344 365 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 174 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 379 397 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 120 144 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 194 212 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 407 426 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 71 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 93 116 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 223 242 7.9E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 276 330 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 5 646 0.0 T 29-03-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 Gene3D G3DSA:1.20.210.10 42 558 7.9E-193 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18080 85100c580c85e23265866fa0f496f1d2 649 SUPERFAMILY SSF81442 44 556 3.79E-176 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07920 465bf74e40390c68c808295267ec15c9 332 PIRSF PIRSF002465 1 332 4.1E-130 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CXR48_RS07920 465bf74e40390c68c808295267ec15c9 332 Gene3D G3DSA:3.40.718.10 1 330 5.4E-108 T 29-03-2018 CXR48_RS07920 465bf74e40390c68c808295267ec15c9 332 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 329 3.9E-146 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CXR48_RS07920 465bf74e40390c68c808295267ec15c9 332 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 332 152.831 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CXR48_RS07920 465bf74e40390c68c808295267ec15c9 332 SUPERFAMILY SSF53659 1 327 9.05E-107 T 29-03-2018 CXR48_RS07920 465bf74e40390c68c808295267ec15c9 332 Pfam PF02504 Fatty acid synthesis protein 1 318 2.1E-131 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CXR48_RS11880 d4efda3f3160827d4e7d5c791bc66763 356 Gene3D G3DSA:3.40.50.300 110 329 1.2E-31 T 29-03-2018 CXR48_RS11880 d4efda3f3160827d4e7d5c791bc66763 356 SMART SM00382 136 259 1.4E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS11880 d4efda3f3160827d4e7d5c791bc66763 356 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 204 218 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CXR48_RS11880 d4efda3f3160827d4e7d5c791bc66763 356 Gene3D G3DSA:3.30.450.90 2 109 7.2E-29 T 29-03-2018 CXR48_RS11880 d4efda3f3160827d4e7d5c791bc66763 356 Pfam PF00437 Type II/IV secretion system protein 12 275 4.3E-77 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CXR48_RS11880 d4efda3f3160827d4e7d5c791bc66763 356 SUPERFAMILY SSF52540 5 308 3.2E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 253 1.2E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 PRINTS PR00046 Major sigma-70 factor signature 206 218 4.7E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 PRINTS PR00046 Major sigma-70 factor signature 223 238 4.7E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 PRINTS PR00046 Major sigma-70 factor signature 58 71 4.7E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 PRINTS PR00046 Major sigma-70 factor signature 238 249 4.7E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 3 253 8.2E-123 T 29-03-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 Gene3D G3DSA:1.10.601.10 1 102 8.1E-20 T 29-03-2018 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 Pfam PF04545 Sigma-70, region 4 202 251 5.2E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 Gene3D G3DSA:1.10.10.10 182 256 5.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 Pfam PF04542 Sigma-70 region 2 34 103 6.5E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 Gene3D G3DSA:1.10.10.10 104 155 3.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 28 253 8.5E-90 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 SUPERFAMILY SSF88659 107 180 5.23E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 SUPERFAMILY SSF88946 4 103 3.01E-27 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 223 249 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 SUPERFAMILY SSF88659 181 253 1.85E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02465 b3e6e535286ff8444493c4fcdc06ab8c 262 Pfam PF04539 Sigma-70 region 3 113 187 5.8E-18 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS18295 01f6f41ca169b03fd4e3fb86b8bc9257 342 Gene3D G3DSA:1.10.3470.10 14 341 3.5E-62 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS18295 01f6f41ca169b03fd4e3fb86b8bc9257 342 SUPERFAMILY SSF81345 16 337 2.35E-78 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS18295 01f6f41ca169b03fd4e3fb86b8bc9257 342 Pfam PF01032 FecCD transport family 28 337 2.2E-87 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CXR48_RS09675 50ba00e7164d1c9a86edad4b025bb693 200 Gene3D G3DSA:3.40.50.1820 6 199 2.8E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS09675 50ba00e7164d1c9a86edad4b025bb693 200 SUPERFAMILY SSF53474 5 198 2.79E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS09675 50ba00e7164d1c9a86edad4b025bb693 200 Pfam PF01738 Dienelactone hydrolase family 71 191 5.3E-9 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 51 312 9.7E-141 T 29-03-2018 IPR014232 Sporulation stage V, protein K CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 SUPERFAMILY SSF52540 41 315 2.41E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 SMART SM00382 91 229 8.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 95 226 3.4E-19 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 PRINTS PR00819 CbxX/CfqX superfamily signature 214 233 3.7E-61 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 PRINTS PR00819 CbxX/CfqX superfamily signature 197 214 3.7E-61 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 PRINTS PR00819 CbxX/CfqX superfamily signature 94 109 3.7E-61 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 PRINTS PR00819 CbxX/CfqX superfamily signature 274 286 3.7E-61 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 PRINTS PR00819 CbxX/CfqX superfamily signature 176 188 3.7E-61 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 PRINTS PR00819 CbxX/CfqX superfamily signature 54 68 3.7E-61 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 PRINTS PR00819 CbxX/CfqX superfamily signature 132 146 3.7E-61 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 PRINTS PR00819 CbxX/CfqX superfamily signature 146 165 3.7E-61 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CXR48_RS08695 3aa82c56931f6e2287f054d59bf27cd0 322 Gene3D G3DSA:3.40.50.300 27 226 8.9E-27 T 29-03-2018 CXR48_RS11995 db837b249ddb7fb62ab7448a979a2de2 309 SUPERFAMILY SSF161098 32 303 3.66E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS11995 db837b249ddb7fb62ab7448a979a2de2 309 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 29 307 1.3E-87 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CXR48_RS11995 db837b249ddb7fb62ab7448a979a2de2 309 Gene3D G3DSA:1.10.3720.10 17 302 7.3E-38 T 29-03-2018 CXR48_RS11995 db837b249ddb7fb62ab7448a979a2de2 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 308 1.2E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 Gene3D G3DSA:1.25.40.10 83 167 0.043 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 Gene3D G3DSA:1.10.10.60 338 480 0.029 T 29-03-2018 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 Gene3D G3DSA:1.25.40.10 246 337 0.0011 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 SMART SM00028 290 323 500.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 SMART SM00028 21 54 3.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 SMART SM00028 187 220 0.032 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 SMART SM00028 55 88 500.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 Gene3D G3DSA:1.25.40.10 18 82 3.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 Gene3D G3DSA:1.25.40.10 168 198 1.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 Gene3D G3DSA:1.25.40.10 199 239 9.9E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 SUPERFAMILY SSF48452 23 123 7.09E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 SUPERFAMILY SSF48452 153 316 7.09E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS16400 ba480039a8297118afdac736b2a4a95f 484 Pfam PF13432 Tetratricopeptide repeat 159 206 0.0053 T 29-03-2018 CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 Gene3D G3DSA:3.40.190.10 176 260 2.7E-10 T 29-03-2018 CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 SUPERFAMILY SSF53850 87 286 3.37E-27 T 29-03-2018 CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.4E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 SUPERFAMILY SSF46785 1 87 1.27E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 Gene3D G3DSA:1.10.10.10 1 91 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 Pfam PF03466 LysR substrate binding domain 87 288 1.4E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS04700 30db06fa4d37b96ad2711956fe1c9da7 291 Gene3D G3DSA:3.40.190.10 92 175 9.4E-15 T 29-03-2018 CXR48_RS06380 f8fdb5cc5bd86d20d82e2203913f56e3 248 ProDom PD120066 SPORULATION STAGE SA II SPOIISA TRANSMEMBRANE MEMBRANE KILLER 1 247 1.0E-114 T 29-03-2018 CXR48_RS06380 f8fdb5cc5bd86d20d82e2203913f56e3 248 Pfam PF14171 Toxin SpoIISA, type II toxin-antitoxin system 3 239 4.0E-90 T 29-03-2018 IPR025940 Toxin SpoIISA, type II toxin-antitoxin system GO:0009405|GO:0016021 CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 Pfam PF07687 Peptidase dimerisation domain 180 273 3.3E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 Gene3D G3DSA:3.40.630.10 259 371 8.1E-11 T 29-03-2018 CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 SUPERFAMILY SSF55031 179 283 2.22E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 367 4.6E-182 T 29-03-2018 IPR010162 Peptidase M20B, peptidase T-like CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 PIRSF PIRSF001123 97 184 1.8E-4 T 29-03-2018 IPR008007 Peptidase M42 CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 PIRSF PIRSF001123 4 102 4.7E-5 T 29-03-2018 IPR008007 Peptidase M42 CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 PIRSF PIRSF001123 262 371 3.0E-6 T 29-03-2018 IPR008007 Peptidase M42 CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 SUPERFAMILY SSF53187 5 175 5.03E-64 T 29-03-2018 CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 SUPERFAMILY SSF53187 287 370 5.03E-64 T 29-03-2018 CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 Gene3D G3DSA:3.40.630.10 2 258 5.8E-52 T 29-03-2018 CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CXR48_RS11460 d4f5c600a43d40192cc562ec4ea7678c 371 Pfam PF01546 Peptidase family M20/M25/M40 73 367 4.0E-25 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS03435 bc355ee66001dcf675a5563b075953c0 291 Pfam PF01061 ABC-2 type transporter 5 227 1.9E-18 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CXR48_RS03435 bc355ee66001dcf675a5563b075953c0 291 PIRSF PIRSF006648 2 291 5.7E-16 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CXR48_RS06450 846738c8bb66440bd239aa71e13c7360 311 SUPERFAMILY SSF141986 144 298 2.35E-42 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CXR48_RS06450 846738c8bb66440bd239aa71e13c7360 311 Gene3D G3DSA:3.40.50.10740 1 153 5.1E-53 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CXR48_RS06450 846738c8bb66440bd239aa71e13c7360 311 Gene3D G3DSA:3.50.30.60 154 307 1.5E-43 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CXR48_RS06450 846738c8bb66440bd239aa71e13c7360 311 SUPERFAMILY SSF52317 3 164 2.84E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS06450 846738c8bb66440bd239aa71e13c7360 311 PIRSF PIRSF028757 2 307 2.9E-87 T 29-03-2018 IPR003507 Peptidase family S66 CXR48_RS06450 846738c8bb66440bd239aa71e13c7360 311 Pfam PF02016 LD-carboxypeptidase 14 293 8.4E-79 T 29-03-2018 IPR003507 Peptidase family S66 CXR48_RS04940 1d7da37dec3cf445159dd7958d57ce3f 314 Hamap MF_01427 3'-5' exoribonuclease YhaM [yhaM]. 1 313 64.87 T 29-03-2018 IPR020873 3'-5' exoribonuclease YhaM GO:0000175 CXR48_RS04940 1d7da37dec3cf445159dd7958d57ce3f 314 SUPERFAMILY SSF109604 145 280 1.85E-17 T 29-03-2018 CXR48_RS04940 1d7da37dec3cf445159dd7958d57ce3f 314 Pfam PF01966 HD domain 161 278 6.6E-13 T 29-03-2018 IPR006674 HD domain CXR48_RS04940 1d7da37dec3cf445159dd7958d57ce3f 314 SMART SM00471 156 288 6.6E-7 T 29-03-2018 IPR003607 HD/PDEase domain CXR48_RS04940 1d7da37dec3cf445159dd7958d57ce3f 314 Gene3D G3DSA:2.40.50.140 13 110 2.2E-11 T 29-03-2018 CXR48_RS04940 1d7da37dec3cf445159dd7958d57ce3f 314 Gene3D G3DSA:1.10.3210.10 120 312 2.9E-16 T 29-03-2018 CXR48_RS09625 7d8e7964ae8258e5fc24e2a27eaf0650 221 Gene3D G3DSA:3.40.50.10320 1 216 2.5E-44 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CXR48_RS09625 7d8e7964ae8258e5fc24e2a27eaf0650 221 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 135 1.2E-25 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CXR48_RS09625 7d8e7964ae8258e5fc24e2a27eaf0650 221 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 3 219 1.5E-109 T 29-03-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 CXR48_RS09625 7d8e7964ae8258e5fc24e2a27eaf0650 221 SUPERFAMILY SSF102588 2 215 5.1E-50 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CXR48_RS04955 eb0a3a6a581974eb37f4e4a42635f80b 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 2 27 8.9E-15 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS04955 eb0a3a6a581974eb37f4e4a42635f80b 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 4 27 1.8E-13 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 SUPERFAMILY SSF55781 270 425 5.23E-11 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 Gene3D G3DSA:3.30.70.270 424 582 3.3E-47 T 29-03-2018 CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 SUPERFAMILY SSF55781 126 279 5.45E-8 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 Pfam PF00990 Diguanylate cyclase, GGDEF domain 425 572 1.5E-41 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 SMART SM00267 413 576 1.6E-54 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 Gene3D G3DSA:3.30.450.40 350 423 8.2E-8 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 Gene3D G3DSA:3.30.450.40 257 342 0.0044 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 Gene3D G3DSA:3.30.450.40 57 256 1.4E-4 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 420 575 2.9E-40 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS13675 077b59ebdfb1ee176afda71419e43c90 582 SUPERFAMILY SSF55073 429 577 9.42E-41 T 29-03-2018 IPR029787 Nucleotide cyclase CXR48_RS07770 0b0f96d696947c24774796ad025f52e6 197 Pfam PF01583 Adenylylsulphate kinase 26 178 2.1E-74 T 29-03-2018 CXR48_RS07770 0b0f96d696947c24774796ad025f52e6 197 SUPERFAMILY SSF52540 22 194 1.43E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07770 0b0f96d696947c24774796ad025f52e6 197 Gene3D G3DSA:3.40.50.300 21 195 1.0E-46 T 29-03-2018 CXR48_RS07770 0b0f96d696947c24774796ad025f52e6 197 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 8 191 2.9E-94 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CXR48_RS07770 0b0f96d696947c24774796ad025f52e6 197 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 24 196 39.641 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CXR48_RS02410 b94a233f2e7e67df8be9036cef0c0bec 121 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 112 3.1E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CXR48_RS02410 b94a233f2e7e67df8be9036cef0c0bec 121 SUPERFAMILY SSF56214 1 117 6.8E-35 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CXR48_RS02410 b94a233f2e7e67df8be9036cef0c0bec 121 Gene3D G3DSA:3.90.470.20 1 121 9.0E-35 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CXR48_RS02410 b94a233f2e7e67df8be9036cef0c0bec 121 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 119 6.0E-39 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CXR48_RS02410 b94a233f2e7e67df8be9036cef0c0bec 121 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 118 7.3E-33 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CXR48_RS02410 b94a233f2e7e67df8be9036cef0c0bec 121 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 120 2.5E-45 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CXR48_RS02410 b94a233f2e7e67df8be9036cef0c0bec 121 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 118 25.843 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CXR48_RS18980 933fad842b5b7d93760f60ef90ad584c 396 Gene3D G3DSA:1.20.1250.20 195 395 4.6E-20 T 29-03-2018 CXR48_RS18980 933fad842b5b7d93760f60ef90ad584c 396 SUPERFAMILY SSF103473 9 385 7.46E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS18980 933fad842b5b7d93760f60ef90ad584c 396 Pfam PF07690 Major Facilitator Superfamily 11 228 1.0E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS18980 933fad842b5b7d93760f60ef90ad584c 396 Gene3D G3DSA:1.20.1250.20 1 191 5.2E-22 T 29-03-2018 CXR48_RS18980 933fad842b5b7d93760f60ef90ad584c 396 ProSitePatterns PS00216 Sugar transport proteins signature 1. 55 71 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS01465 1f0d21b14c97538e90099a331c57899b 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 5.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS01465 1f0d21b14c97538e90099a331c57899b 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 5.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS01465 1f0d21b14c97538e90099a331c57899b 188 SUPERFAMILY SSF46689 5 69 1.95E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS01465 1f0d21b14c97538e90099a331c57899b 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 57 5.2E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS01465 1f0d21b14c97538e90099a331c57899b 188 Gene3D G3DSA:1.10.10.60 3 54 1.9E-13 T 29-03-2018 CXR48_RS01465 1f0d21b14c97538e90099a331c57899b 188 SUPERFAMILY SSF48498 78 187 1.07E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS01465 1f0d21b14c97538e90099a331c57899b 188 Gene3D G3DSA:1.10.357.10 55 187 8.0E-17 T 29-03-2018 CXR48_RS07330 f4dadfa76fb56bfed2e9507f110dbb82 150 Pfam PF00583 Acetyltransferase (GNAT) family 30 129 1.4E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS07330 f4dadfa76fb56bfed2e9507f110dbb82 150 SUPERFAMILY SSF55729 2 150 2.34E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS07330 f4dadfa76fb56bfed2e9507f110dbb82 150 Gene3D G3DSA:3.40.630.30 1 149 1.9E-12 T 29-03-2018 CXR48_RS18765 ccec0014c18b102653f787b97a685e28 378 Gene3D G3DSA:3.30.565.10 242 370 2.3E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18765 ccec0014c18b102653f787b97a685e28 378 Pfam PF07730 Histidine kinase 178 241 3.7E-21 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CXR48_RS18765 ccec0014c18b102653f787b97a685e28 378 SUPERFAMILY SSF55874 250 366 3.01E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13230 966613df815f56fb9f684c651dca8fdb 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 1.0E-108 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CXR48_RS13230 966613df815f56fb9f684c651dca8fdb 344 SUPERFAMILY SSF55681 93 342 9.76E-83 T 29-03-2018 CXR48_RS13230 966613df815f56fb9f684c651dca8fdb 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 48.77 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CXR48_RS13230 966613df815f56fb9f684c651dca8fdb 344 Gene3D G3DSA:3.30.930.10 8 344 2.1E-95 T 29-03-2018 CXR48_RS13230 966613df815f56fb9f684c651dca8fdb 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 342 5.1E-118 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CXR48_RS13230 966613df815f56fb9f684c651dca8fdb 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 7.7E-26 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CXR48_RS13230 966613df815f56fb9f684c651dca8fdb 344 SUPERFAMILY SSF46589 15 99 1.41E-20 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CXR48_RS13165 14205ac21c5c851485bdeb6e524c1748 325 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 8.5E-36 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CXR48_RS13165 14205ac21c5c851485bdeb6e524c1748 325 Gene3D G3DSA:3.40.50.620 3 191 2.5E-45 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS13165 14205ac21c5c851485bdeb6e524c1748 325 PIRSF PIRSF000089 1 322 2.9E-114 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CXR48_RS13165 14205ac21c5c851485bdeb6e524c1748 325 SUPERFAMILY SSF52467 198 317 1.41E-48 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS13165 14205ac21c5c851485bdeb6e524c1748 325 SUPERFAMILY SSF52402 3 191 2.93E-48 T 29-03-2018 CXR48_RS13165 14205ac21c5c851485bdeb6e524c1748 325 SMART SM00893 5 195 3.5E-45 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CXR48_RS13165 14205ac21c5c851485bdeb6e524c1748 325 Pfam PF01012 Electron transfer flavoprotein domain 7 179 1.3E-42 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CXR48_RS13165 14205ac21c5c851485bdeb6e524c1748 325 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CXR48_RS13165 14205ac21c5c851485bdeb6e524c1748 325 Gene3D G3DSA:3.40.50.1220 194 324 1.5E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS12905 9247d676239a15399937a91064fa0100 287 Pfam PF04085 rod shape-determining protein MreC 119 276 7.8E-43 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CXR48_RS12905 9247d676239a15399937a91064fa0100 287 PIRSF PIRSF038471 1 286 8.2E-60 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CXR48_RS12905 9247d676239a15399937a91064fa0100 287 Gene3D G3DSA:1.20.58.130 59 150 0.0016 T 29-03-2018 CXR48_RS12905 9247d676239a15399937a91064fa0100 287 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 284 6.6E-105 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CXR48_RS10740 a8b76a404f872f3346c349b99953904f 217 Gene3D G3DSA:3.20.20.70 3 213 7.3E-54 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS10740 a8b76a404f872f3346c349b99953904f 217 SUPERFAMILY SSF51366 6 208 2.83E-43 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CXR48_RS10740 a8b76a404f872f3346c349b99953904f 217 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 7 206 3.9E-47 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CXR48_RS10740 a8b76a404f872f3346c349b99953904f 217 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 4 212 31.611 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CXR48_RS05905 9dc4beffbcc2ab96baab55684b590793 128 SUPERFAMILY SSF54593 1 126 5.77E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS05905 9dc4beffbcc2ab96baab55684b590793 128 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CXR48_RS05905 9dc4beffbcc2ab96baab55684b590793 128 Pfam PF12681 Glyoxalase-like domain 8 125 2.2E-17 T 29-03-2018 IPR025870 Glyoxalase-like domain CXR48_RS05905 9dc4beffbcc2ab96baab55684b590793 128 Gene3D G3DSA:3.10.180.10 1 128 1.6E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS06920 3e0100fc14975673c14a719f53336a08 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 228 241 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CXR48_RS06920 3e0100fc14975673c14a719f53336a08 389 Pfam PF00155 Aminotransferase class I and II 29 375 1.3E-63 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS06920 3e0100fc14975673c14a719f53336a08 389 Gene3D G3DSA:3.40.640.10 43 292 1.5E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS06920 3e0100fc14975673c14a719f53336a08 389 SUPERFAMILY SSF53383 4 379 2.42E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS06920 3e0100fc14975673c14a719f53336a08 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 113 134 1.6E-11 T 29-03-2018 CXR48_RS06920 3e0100fc14975673c14a719f53336a08 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 195 218 1.6E-11 T 29-03-2018 CXR48_RS06920 3e0100fc14975673c14a719f53336a08 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 159 183 1.6E-11 T 29-03-2018 CXR48_RS06920 3e0100fc14975673c14a719f53336a08 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 91 111 1.6E-11 T 29-03-2018 CXR48_RS06920 3e0100fc14975673c14a719f53336a08 389 Gene3D G3DSA:3.90.1150.10 293 383 3.6E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS05425 6464a45b595d40c3dc5b32d64da31261 291 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 93 220 2.5E-29 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS05425 6464a45b595d40c3dc5b32d64da31261 291 Gene3D G3DSA:1.10.287.950 31 291 3.6E-43 T 29-03-2018 CXR48_RS05425 6464a45b595d40c3dc5b32d64da31261 291 SUPERFAMILY SSF58104 32 289 1.83E-47 T 29-03-2018 CXR48_RS05425 6464a45b595d40c3dc5b32d64da31261 291 SMART SM00283 24 290 2.5E-27 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 Pfam PF00710 Asparaginase, N-terminal 3 186 4.5E-65 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 SMART SM00870 3 316 3.4E-120 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 PIRSF PIRSF500176 1 325 8.2E-110 T 29-03-2018 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 Gene3D G3DSA:3.40.50.1170 1 201 2.9E-65 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 Gene3D G3DSA:3.40.50.40 203 328 1.3E-30 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 PIRSF PIRSF001220 1 327 3.9E-101 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 1 328 5.2E-142 T 29-03-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 SUPERFAMILY SSF53774 1 327 1.83E-100 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 7.3E-16 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 7.3E-16 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS11195 52a803fc692acfabe53db88fcccee8f5 329 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 7.3E-16 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS19135 eea055d7fca10c3e4405215a30356316 659 SMART SM00267 132 299 1.2E-16 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS19135 eea055d7fca10c3e4405215a30356316 659 Pfam PF01368 DHH family 339 496 2.4E-21 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CXR48_RS19135 eea055d7fca10c3e4405215a30356316 659 PIRSF PIRSF026583 1 659 4.4E-277 T 29-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CXR48_RS19135 eea055d7fca10c3e4405215a30356316 659 Gene3D G3DSA:3.30.70.270 129 300 2.3E-7 T 29-03-2018 CXR48_RS19135 eea055d7fca10c3e4405215a30356316 659 SUPERFAMILY SSF64182 339 644 2.49E-67 T 29-03-2018 CXR48_RS19135 eea055d7fca10c3e4405215a30356316 659 Pfam PF02272 DHHA1 domain 518 649 1.6E-13 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CXR48_RS19135 eea055d7fca10c3e4405215a30356316 659 Gene3D G3DSA:3.90.1640.10 317 536 2.6E-47 T 29-03-2018 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 Pfam PF16124 RecQ zinc-binding 337 398 3.0E-17 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 Gene3D G3DSA:1.10.150.80 518 591 3.0E-26 T 29-03-2018 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 SMART SM00956 406 509 4.7E-42 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 Pfam PF00270 DEAD/DEAH box helicase 21 182 1.5E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 SMART SM00341 514 592 1.5E-21 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 Pfam PF09382 RQC domain 403 508 7.4E-32 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 Gene3D G3DSA:3.40.50.300 203 347 6.4E-33 T 29-03-2018 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 Gene3D G3DSA:3.40.50.300 2 202 1.1E-33 T 29-03-2018 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 SUPERFAMILY SSF52540 59 346 1.98E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 Gene3D G3DSA:1.10.10.10 348 517 1.2E-48 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 458 1.2E-147 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 6 587 1.3E-232 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 SUPERFAMILY SSF46785 397 539 2.18E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 Pfam PF00271 Helicase conserved C-terminal domain 217 324 1.6E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 Pfam PF00570 HRDC domain 519 584 1.6E-22 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 SMART SM00490 244 325 2.0E-26 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 SUPERFAMILY SSF47819 515 590 3.36E-25 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CXR48_RS09485 2e2369e531d2a0ce77be888232879e3b 592 SMART SM00487 14 212 6.4E-30 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 PIRSF PIRSF001554 1 385 6.0E-155 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 Pfam PF00549 CoA-ligase 262 381 3.8E-26 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 SUPERFAMILY SSF52210 239 384 1.96E-54 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 Gene3D G3DSA:3.30.470.20 97 239 1.2E-55 T 29-03-2018 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 Gene3D G3DSA:3.40.50.261 240 385 4.5E-42 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 Gene3D G3DSA:3.30.1490.20 21 96 7.4E-25 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 Pfam PF08442 ATP-grasp domain 2 203 5.0E-85 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 385 44.515 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 384 6.4E-168 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CXR48_RS08020 cca56433021207c0842d6103cf33d4b7 385 SUPERFAMILY SSF56059 1 238 1.38E-85 T 29-03-2018 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 SMART SM00562 1 138 2.3E-90 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 SUPERFAMILY SSF54919 1 148 3.8E-62 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 29-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 Gene3D G3DSA:3.30.70.141 1 148 8.0E-59 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 37.265 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 3.1E-52 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 3.1E-52 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 3.1E-52 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 3.1E-52 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 3.1E-52 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS10780 617b8a1654908d3b29014728e4cdb672 148 Pfam PF00334 Nucleoside diphosphate kinase 2 135 1.1E-58 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 7.3E-12 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 325 338 7.3E-12 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 7.3E-12 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 Gene3D G3DSA:3.40.50.880 140 355 7.3E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 SMART SM01097 1 131 8.5E-89 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 351 2.3E-145 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 6.0E-37 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 6.0E-37 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 6.0E-37 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 6.0E-37 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 6.0E-37 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00097 Anthranilate synthase component II signature 214 223 1.3E-6 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00097 Anthranilate synthase component II signature 241 252 1.3E-6 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00097 Anthranilate synthase component II signature 325 338 1.3E-6 T 29-03-2018 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 354 48.825 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 Pfam PF00117 Glutamine amidotransferase class-I 174 348 3.1E-46 T 29-03-2018 IPR017926 Glutamine amidotransferase CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 SUPERFAMILY SSF52317 140 351 9.35E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 Gene3D G3DSA:3.50.30.20 1 139 5.1E-59 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 8.7E-53 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07725 0695c4e13179af8fe9f71eb5f15ee684 364 SUPERFAMILY SSF52021 1 144 1.31E-57 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 PRINTS PR01398 Isochorismatase signature 63 80 3.9E-49 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 PRINTS PR01398 Isochorismatase signature 186 203 3.9E-49 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 PRINTS PR01398 Isochorismatase signature 80 99 3.9E-49 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 PRINTS PR01398 Isochorismatase signature 2 14 3.9E-49 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 PRINTS PR01398 Isochorismatase signature 112 134 3.9E-49 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 PRINTS PR01398 Isochorismatase signature 168 186 3.9E-49 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 SUPERFAMILY SSF47336 227 297 2.49E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 PIRSF PIRSF001111 1 302 5.0E-132 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 Gene3D G3DSA:1.10.1200.10 223 301 3.1E-12 T 29-03-2018 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 Gene3D G3DSA:3.40.50.850 1 211 1.1E-45 T 29-03-2018 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 Pfam PF00857 Isochorismatase family 32 202 9.9E-42 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 SUPERFAMILY SSF52499 2 210 1.01E-61 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS14885 d14471af6be62d5f4f159aaa2e6b9122 308 Pfam PF00550 Phosphopantetheine attachment site 229 290 1.4E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07705 e2d52224fea95f7d60e7c7003a5bd426 181 SUPERFAMILY SSF53271 5 172 1.05E-43 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS07705 e2d52224fea95f7d60e7c7003a5bd426 181 Pfam PF00156 Phosphoribosyl transferase domain 7 151 3.6E-22 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CXR48_RS07705 e2d52224fea95f7d60e7c7003a5bd426 181 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 179 39.16 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CXR48_RS07705 e2d52224fea95f7d60e7c7003a5bd426 181 Gene3D G3DSA:3.40.50.2020 1 181 1.2E-42 T 29-03-2018 CXR48_RS12670 ac75455d2c3775db3227a02cc37aff28 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 359 40.528 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CXR48_RS12670 ac75455d2c3775db3227a02cc37aff28 371 Gene3D G3DSA:2.40.30.10 279 371 3.5E-27 T 29-03-2018 CXR48_RS12670 ac75455d2c3775db3227a02cc37aff28 371 Gene3D G3DSA:2.30.30.280 214 277 4.8E-26 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CXR48_RS12670 ac75455d2c3775db3227a02cc37aff28 371 Gene3D G3DSA:3.40.50.620 1 213 7.3E-68 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS12670 ac75455d2c3775db3227a02cc37aff28 371 Pfam PF03054 tRNA methyl transferase 9 358 8.9E-151 T 29-03-2018 CXR48_RS12670 ac75455d2c3775db3227a02cc37aff28 371 SUPERFAMILY SSF52402 7 244 9.92E-60 T 29-03-2018 CXR48_RS12670 ac75455d2c3775db3227a02cc37aff28 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 358 5.0E-139 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PIRSF PIRSF002133 1 137 2.2E-49 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.782 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 2.2E-69 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.7E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.7E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.7E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.7E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.7E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.7E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 SUPERFAMILY SSF50249 2 136 2.83E-49 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 Gene3D G3DSA:2.40.50.140 1 138 1.3E-64 T 29-03-2018 CXR48_RS00705 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 Pfam PF00164 Ribosomal protein S12/S23 36 136 4.6E-38 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS09790 7662b2cd9724a0393b11cc8bb2b35789 435 Pfam PF07687 Peptidase dimerisation domain 203 315 2.4E-17 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS09790 7662b2cd9724a0393b11cc8bb2b35789 435 SUPERFAMILY SSF55031 205 313 4.93E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS09790 7662b2cd9724a0393b11cc8bb2b35789 435 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 22 411 1.4E-131 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CXR48_RS09790 7662b2cd9724a0393b11cc8bb2b35789 435 Gene3D G3DSA:3.40.630.10 1 314 2.0E-60 T 29-03-2018 CXR48_RS09790 7662b2cd9724a0393b11cc8bb2b35789 435 SUPERFAMILY SSF53187 336 421 6.0E-60 T 29-03-2018 CXR48_RS09790 7662b2cd9724a0393b11cc8bb2b35789 435 SUPERFAMILY SSF53187 8 205 6.0E-60 T 29-03-2018 CXR48_RS09790 7662b2cd9724a0393b11cc8bb2b35789 435 Pfam PF01546 Peptidase family M20/M25/M40 99 417 2.5E-40 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS06100 23a1e2c8a02f4c9b7c46922979f78959 223 SMART SM00862 145 221 1.2E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS06100 23a1e2c8a02f4c9b7c46922979f78959 223 Gene3D G3DSA:1.10.10.10 124 223 2.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06100 23a1e2c8a02f4c9b7c46922979f78959 223 Gene3D G3DSA:3.40.50.2300 2 123 2.4E-21 T 29-03-2018 CXR48_RS06100 23a1e2c8a02f4c9b7c46922979f78959 223 SMART SM00448 2 110 9.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS06100 23a1e2c8a02f4c9b7c46922979f78959 223 Pfam PF00072 Response regulator receiver domain 4 111 4.4E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS06100 23a1e2c8a02f4c9b7c46922979f78959 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.6E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS06100 23a1e2c8a02f4c9b7c46922979f78959 223 SUPERFAMILY SSF46894 131 221 1.08E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS06100 23a1e2c8a02f4c9b7c46922979f78959 223 SUPERFAMILY SSF52172 3 116 2.28E-28 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 ProSitePatterns PS00455 Putative AMP-binding domain signature. 634 645 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF51735 2179 2406 3.01E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF14765 Polyketide synthase dehydratase 4668 4950 6.5E-59 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF14765 Polyketide synthase dehydratase 3196 3477 8.4E-63 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF14765 Polyketide synthase dehydratase 1702 1993 1.1E-48 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3661 3847 2.0E-51 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5166 5346 5.0E-31 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2182 2368 2.8E-44 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.30.559.10 16 229 1.4E-29 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF53901 4464 4482 2.81E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF53901 4048 4422 2.81E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF08659 KR domain 2182 2367 2.2E-53 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF08659 KR domain 5166 5344 5.6E-41 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF08659 KR domain 3661 3846 2.5E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:1.10.1200.10 1008 1083 5.4E-18 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4210 4226 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF13193 AMP-binding enzyme C-terminal domain 904 977 5.5E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF52777 217 468 5.56E-48 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4051 4297 2.3E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1103 1352 1.0E-60 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2574 2822 2.8E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.10.129.10 4666 4795 2.0E-20 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.10.129.10 1699 1832 2.8E-14 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.10.129.10 3196 3323 1.1E-18 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.50.980 483 639 9.1E-49 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 513 918 3.2E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.47.10 4043 4309 2.1E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.47.10 1098 1364 3.3E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.50.720 5156 5413 5.9E-33 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF53901 1101 1220 2.28E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF53901 1248 1471 2.28E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF53901 1506 1527 2.28E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.50.720 3655 3914 6.6E-44 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.50.720 2177 2433 4.9E-45 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF51735 4986 5153 1.88E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF51735 5163 5382 1.56E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF56801 449 1017 1.23E-154 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2735 2751 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1029 1044 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4433 4551 1.1E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1481 1595 8.6E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2955 3068 2.0E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00826 4668 4835 7.0E-10 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00826 1702 1867 3.8E-5 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00826 3196 3360 3.0E-23 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:2.30.38.10 805 885 2.5E-26 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF47336 2558 2588 1.3E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF47336 2449 2523 1.3E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4305 4429 2.7E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2830 2951 1.8E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1360 1478 1.3E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF47336 3930 4003 1.11E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF47336 4035 4064 1.11E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF00550 Phosphopantetheine attachment site 2454 2517 5.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF00550 Phosphopantetheine attachment site 3934 3998 1.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF00550 Phosphopantetheine attachment site 1007 1070 1.7E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.30.300.30 890 1007 9.9E-34 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF53901 2571 2944 6.04E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF53901 2985 3005 6.04E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.50.980 640 804 5.6E-35 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF00501 AMP-binding enzyme 492 895 7.0E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:2.30.40.10 3031 3150 0.031 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM01294 3928 3998 5.7E-7 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM01294 2452 2518 2.1E-6 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00825 Beta-ketoacyl synthase 2576 3010 1.9E-200 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00825 Beta-ketoacyl synthase 1105 1531 4.2E-139 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00825 Beta-ketoacyl synthase 4053 4488 1.0E-188 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.47.10 2837 3008 3.1E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.47.10 4312 4486 2.4E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.47.10 1367 1529 2.0E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF52777 36 208 6.34E-35 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00823 Phosphopantetheine attachment site 3931 4002 4.9E-16 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00823 Phosphopantetheine attachment site 2451 2522 2.4E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SMART SM00823 Phosphopantetheine attachment site 1005 1074 7.5E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:3.40.47.10 2566 2833 3.5E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Pfam PF00668 Condensation domain 34 462 4.6E-105 T 29-03-2018 IPR001242 Condensation domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF47336 999 1071 4.32E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:1.10.1200.10 3915 4007 1.0E-15 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 Gene3D G3DSA:1.10.1200.10 2434 2530 1.7E-12 T 29-03-2018 CXR48_RS08575 7a403dd7190f1e2c097f482a3f757f19 5432 SUPERFAMILY SSF51735 3657 3885 3.66E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 18 521 3.9E-207 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 245 299 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 289 304 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 17 42 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 366 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 313 334 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 181 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 64 87 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 133 145 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 211 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 426 447 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 91 115 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 2.8E-103 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 Gene3D G3DSA:1.10.287.70 537 609 6.6E-14 T 29-03-2018 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 SUPERFAMILY SSF81442 14 523 2.22E-177 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 Gene3D G3DSA:1.20.210.10 13 525 1.2E-192 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07425 cc6dd6934ef950ebffa182c16efc88da 622 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 469 4.4E-147 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07575 a96c3985442b4ea803872884706fe507 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CXR48_RS07575 a96c3985442b4ea803872884706fe507 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 323 5.4E-129 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CXR48_RS07575 a96c3985442b4ea803872884706fe507 324 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CXR48_RS07575 a96c3985442b4ea803872884706fe507 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 24.637 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CXR48_RS07575 a96c3985442b4ea803872884706fe507 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 1.4E-5 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CXR48_RS07575 a96c3985442b4ea803872884706fe507 324 Pfam PF00953 Glycosyl transferase family 4 82 248 9.9E-39 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CXR48_RS07670 329066a37890494d6215bc00b3c9f35b 256 SUPERFAMILY SSF55174 177 250 1.41E-33 T 29-03-2018 CXR48_RS07670 329066a37890494d6215bc00b3c9f35b 256 SUPERFAMILY SSF55174 36 125 1.41E-33 T 29-03-2018 CXR48_RS07670 329066a37890494d6215bc00b3c9f35b 256 Pfam PF01479 S4 domain 181 225 7.4E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS07670 329066a37890494d6215bc00b3c9f35b 256 SMART SM00363 180 237 2.0E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS07670 329066a37890494d6215bc00b3c9f35b 256 Gene3D G3DSA:3.10.290.10 179 231 2.4E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS17645 6b0b2bda526300d5da7e534b01283ec3 238 Gene3D G3DSA:2.60.120.10 2 138 5.5E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS17645 6b0b2bda526300d5da7e534b01283ec3 238 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 7.0E-17 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CXR48_RS17645 6b0b2bda526300d5da7e534b01283ec3 238 SMART SM00100 9 129 9.3E-19 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CXR48_RS17645 6b0b2bda526300d5da7e534b01283ec3 238 SUPERFAMILY SSF51206 17 145 1.44E-30 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CXR48_RS17645 6b0b2bda526300d5da7e534b01283ec3 238 SUPERFAMILY SSF46785 147 233 2.14E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17645 6b0b2bda526300d5da7e534b01283ec3 238 ProSitePatterns PS00042 Crp-type HTH domain signature. 176 199 - T 29-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 CXR48_RS17645 6b0b2bda526300d5da7e534b01283ec3 238 Pfam PF13545 Crp-like helix-turn-helix domain 151 222 1.3E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CXR48_RS17645 6b0b2bda526300d5da7e534b01283ec3 238 SMART SM00419 168 217 1.5E-11 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CXR48_RS17645 6b0b2bda526300d5da7e534b01283ec3 238 Gene3D G3DSA:1.10.10.10 139 226 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14940 0e316b1bfe62746b736e9fe9ec03d4c8 106 Pfam PF14068 Putative membrane protein 7 106 4.7E-43 T 29-03-2018 IPR025917 Putative membrane protein YuiB CXR48_RS05605 da510507609b575297cde405efbdc889 330 Gene3D G3DSA:1.10.240.10 200 308 8.3E-35 T 29-03-2018 CXR48_RS05605 da510507609b575297cde405efbdc889 330 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 326 42.097 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CXR48_RS05605 da510507609b575297cde405efbdc889 330 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 325 1.6E-123 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CXR48_RS05605 da510507609b575297cde405efbdc889 330 Pfam PF00579 tRNA synthetases class I (W and Y) 4 281 1.1E-81 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS05605 da510507609b575297cde405efbdc889 330 Gene3D G3DSA:3.40.50.620 1 199 5.2E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS05605 da510507609b575297cde405efbdc889 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 3.7E-29 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CXR48_RS05605 da510507609b575297cde405efbdc889 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 3.7E-29 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CXR48_RS05605 da510507609b575297cde405efbdc889 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 3.7E-29 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CXR48_RS05605 da510507609b575297cde405efbdc889 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 3.7E-29 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CXR48_RS05605 da510507609b575297cde405efbdc889 330 SUPERFAMILY SSF52374 4 325 4.22E-98 T 29-03-2018 CXR48_RS05605 da510507609b575297cde405efbdc889 330 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 20 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS01560 6b2683a789eee53e08e96d5609fa7351 257 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 32 240 1.1E-79 T 29-03-2018 IPR022493 Integral membrane YkoY CXR48_RS01560 6b2683a789eee53e08e96d5609fa7351 257 Pfam PF03741 Integral membrane protein TerC family 35 212 2.6E-51 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CXR48_RS14065 50990db29c116baebe9003cca5f90b39 292 SMART SM00382 26 203 8.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS14065 50990db29c116baebe9003cca5f90b39 292 Pfam PF00005 ABC transporter 17 154 1.3E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS14065 50990db29c116baebe9003cca5f90b39 292 SUPERFAMILY SSF52540 1 218 5.43E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14065 50990db29c116baebe9003cca5f90b39 292 Gene3D G3DSA:3.40.50.300 1 269 1.6E-47 T 29-03-2018 CXR48_RS17290 235b2379e2235fdb5f847b89f294d7a8 145 Pfam PF17370 Family of unknown function (DUF5392) 6 141 4.8E-48 T 29-03-2018 IPR020205 Uncharacterised protein family, YwnF, transmembrane CXR48_RS17290 235b2379e2235fdb5f847b89f294d7a8 145 ProDom PD087515 YWNF MEMBRANE SYNTHASE BH1886 BETA-KETOACYL TRANSMEMBRANE 1 141 1.0E-24 T 29-03-2018 IPR020205 Uncharacterised protein family, YwnF, transmembrane CXR48_RS01300 dccd36409f97bab08503cac4154bfd8c 356 Gene3D G3DSA:3.40.50.1970 11 153 2.1E-19 T 29-03-2018 CXR48_RS01300 dccd36409f97bab08503cac4154bfd8c 356 SUPERFAMILY SSF56796 10 329 9.94E-57 T 29-03-2018 CXR48_RS01300 dccd36409f97bab08503cac4154bfd8c 356 PIRSF PIRSF000112 1 355 1.5E-109 T 29-03-2018 CXR48_RS01300 dccd36409f97bab08503cac4154bfd8c 356 Gene3D G3DSA:1.20.1090.10 154 355 4.0E-24 T 29-03-2018 CXR48_RS01300 dccd36409f97bab08503cac4154bfd8c 356 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 332 9.4E-49 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 SMART SM00436 126 216 1.6E-45 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 Gene3D G3DSA:2.70.20.10 349 461 4.4E-34 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 637 69.204 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 299 314 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 Pfam PF01131 DNA topoisomerase 152 582 1.1E-123 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 Pfam PF01751 Toprim domain 5 134 1.5E-13 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 Gene3D G3DSA:3.40.50.140 3 154 9.0E-40 T 29-03-2018 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 SMART SM00493 3 126 5.7E-22 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 SUPERFAMILY SSF56712 3 598 1.31E-175 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 Gene3D G3DSA:3.30.65.10 646 691 0.39 T 29-03-2018 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 Gene3D G3DSA:3.30.65.10 598 645 2.3E-5 T 29-03-2018 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 SMART SM00437 262 548 3.1E-111 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 305 314 1.4E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 511 525 1.4E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.4E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 1.4E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 387 403 1.4E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 Gene3D G3DSA:1.10.460.10 159 341 4.1E-36 T 29-03-2018 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 Gene3D G3DSA:1.10.460.10 462 597 1.5E-19 T 29-03-2018 CXR48_RS02190 c7b1fd42bb6ee3723958eec0f67bd7cb 728 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 728 0.0 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 145 164 4.6E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 91 103 4.6E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 40 56 4.6E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 ProSitePatterns PS00760 Signal peptidases I lysine active site. 93 105 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 Pfam PF00717 Peptidase S24-like 47 115 4.1E-20 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 ProSitePatterns PS00501 Signal peptidases I serine active site. 49 56 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 25 186 1.2E-52 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 Gene3D G3DSA:2.10.109.10 36 193 1.0E-44 T 29-03-2018 CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 ProSitePatterns PS00761 Signal peptidases I signature 3. 150 163 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CXR48_RS07115 7ba92ee0dc97e5e747561ca608a7762e 193 SUPERFAMILY SSF51306 38 190 4.06E-50 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS02820 8388da1279c4d87ba4c9ef585c28c013 175 Pfam PF13302 Acetyltransferase (GNAT) domain 7 141 1.6E-33 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS02820 8388da1279c4d87ba4c9ef585c28c013 175 SUPERFAMILY SSF55729 2 165 1.61E-50 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS02820 8388da1279c4d87ba4c9ef585c28c013 175 Gene3D G3DSA:3.40.630.30 1 168 1.0E-36 T 29-03-2018 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 Gene3D G3DSA:2.40.10.170 1 82 4.6E-31 T 29-03-2018 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 80 1.3E-23 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 351 6.0E-67 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 SUPERFAMILY SSF50615 2 82 6.54E-27 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 SUPERFAMILY SSF52540 84 354 2.83E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 Gene3D G3DSA:1.10.1140.10 357 467 4.4E-43 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 Gene3D G3DSA:3.40.50.300 83 356 2.4E-90 T 29-03-2018 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 469 57.555 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 SUPERFAMILY SSF47917 354 469 1.46E-51 T 29-03-2018 CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 SMART SM00382 150 335 1.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS17400 e4ec49fe757cc31db146d6b6d3b61d40 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 469 9.5E-258 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CXR48_RS13430 76b47570695cd391a894923f9a746836 197 Gene3D G3DSA:3.40.50.300 2 197 1.8E-47 T 29-03-2018 CXR48_RS13430 76b47570695cd391a894923f9a746836 197 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 195 28.565 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CXR48_RS13430 76b47570695cd391a894923f9a746836 197 SUPERFAMILY SSF52540 4 194 3.58E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS13430 76b47570695cd391a894923f9a746836 197 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 191 6.3E-69 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CXR48_RS13430 76b47570695cd391a894923f9a746836 197 Pfam PF01121 Dephospho-CoA kinase 3 182 5.1E-62 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CXR48_RS04550 dc96dda1f0ae6f043d1445aff2d4f387 359 Gene3D G3DSA:3.30.70.270 186 359 2.0E-49 T 29-03-2018 CXR48_RS04550 dc96dda1f0ae6f043d1445aff2d4f387 359 Pfam PF07694 5TMR of 5TMR-LYT 22 176 5.7E-15 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CXR48_RS04550 dc96dda1f0ae6f043d1445aff2d4f387 359 SUPERFAMILY SSF55073 197 355 9.42E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CXR48_RS04550 dc96dda1f0ae6f043d1445aff2d4f387 359 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 189 353 3.1E-44 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS04550 dc96dda1f0ae6f043d1445aff2d4f387 359 SMART SM00267 181 355 2.9E-56 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS04550 dc96dda1f0ae6f043d1445aff2d4f387 359 Pfam PF00990 Diguanylate cyclase, GGDEF domain 192 351 1.6E-42 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS14950 517810b3052d2d2b8b0feb0fddaf2a6c 406 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 327 1.3E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS14950 517810b3052d2d2b8b0feb0fddaf2a6c 406 Gene3D G3DSA:3.50.50.60 6 130 2.5E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS14950 517810b3052d2d2b8b0feb0fddaf2a6c 406 Gene3D G3DSA:3.50.50.60 131 336 1.8E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS14950 517810b3052d2d2b8b0feb0fddaf2a6c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.6E-5 T 29-03-2018 CXR48_RS14950 517810b3052d2d2b8b0feb0fddaf2a6c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.6E-5 T 29-03-2018 CXR48_RS14950 517810b3052d2d2b8b0feb0fddaf2a6c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 1.6E-5 T 29-03-2018 CXR48_RS14950 517810b3052d2d2b8b0feb0fddaf2a6c 406 SUPERFAMILY SSF51905 5 172 1.76E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS14950 517810b3052d2d2b8b0feb0fddaf2a6c 406 SUPERFAMILY SSF51905 217 340 1.76E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS08220 d67cd4a3a5d4a2efad5f7f7555d177c3 157 Gene3D G3DSA:1.10.10.60 91 124 0.002 T 29-03-2018 CXR48_RS08220 d67cd4a3a5d4a2efad5f7f7555d177c3 157 ProDom PD177368 TRANSCRIPTION DNA-BINDING MOTILITY SWRB SWARMING YLXL REGULATION BH2428 1 154 8.0E-35 T 29-03-2018 CXR48_RS08220 d67cd4a3a5d4a2efad5f7f7555d177c3 157 Gene3D G3DSA:1.10.10.60 125 149 0.0016 T 29-03-2018 CXR48_RS09805 e3d702524e747a3d8fa5ad02ba464c0a 443 SUPERFAMILY SSF53383 15 432 8.97E-114 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS09805 e3d702524e747a3d8fa5ad02ba464c0a 443 Gene3D G3DSA:3.90.1150.10 9 193 2.7E-39 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS09805 e3d702524e747a3d8fa5ad02ba464c0a 443 PIRSF PIRSF000521 10 397 5.5E-34 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS09805 e3d702524e747a3d8fa5ad02ba464c0a 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS09805 e3d702524e747a3d8fa5ad02ba464c0a 443 Pfam PF00202 Aminotransferase class-III 17 431 6.5E-101 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS09805 e3d702524e747a3d8fa5ad02ba464c0a 443 Gene3D G3DSA:3.90.1150.10 246 436 6.4E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 52 70 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 SUPERFAMILY SSF53706 8 1065 0.0 T 29-03-2018 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 768 785 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 7 1227 0.0 T 29-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 Gene3D G3DSA:3.40.228.10 229 601 2.6E-82 T 29-03-2018 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 Gene3D G3DSA:3.40.50.740 618 922 8.8E-39 T 29-03-2018 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 SMART SM00926 47 109 6.0E-7 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 9 44 4.6E-14 T 29-03-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 Gene3D G3DSA:3.40.50.740 112 217 0.045 T 29-03-2018 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 Gene3D G3DSA:2.20.25.90 59 102 1.2E-25 T 29-03-2018 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 Gene3D G3DSA:2.40.40.20 1042 1228 1.7E-40 T 29-03-2018 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 Pfam PF01568 Molydopterin dinucleotide binding domain 1080 1194 5.9E-21 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 Pfam PF00384 Molybdopterin oxidoreductase 112 824 1.6E-188 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 SUPERFAMILY SSF50692 1074 1226 1.7E-44 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CXR48_RS17630 da8f9135b32b7a2c15f5d788d8a4e44b 1228 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1117 1144 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CXR48_RS18325 8f0c2a53febf9479f75618356cdb51cd 105 Gene3D G3DSA:1.20.58.80 5 102 4.0E-34 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS18325 8f0c2a53febf9479f75618356cdb51cd 105 PIRSF PIRSF000699 1 105 4.6E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS18325 8f0c2a53febf9479f75618356cdb51cd 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 101 3.0E-33 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS18325 8f0c2a53febf9479f75618356cdb51cd 105 SUPERFAMILY SSF46973 2 101 7.59E-34 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS04520 8bfe577389b1d4542c1ef7f8825cf159 238 Gene3D G3DSA:3.40.50.300 1 235 1.2E-49 T 29-03-2018 CXR48_RS04520 8bfe577389b1d4542c1ef7f8825cf159 238 SMART SM00382 27 203 5.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04520 8bfe577389b1d4542c1ef7f8825cf159 238 SUPERFAMILY SSF52540 3 229 1.9E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04520 8bfe577389b1d4542c1ef7f8825cf159 238 Pfam PF00005 ABC transporter 19 153 2.0E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS02945 796d836d7078542554605225385816fc 104 SUPERFAMILY SSF103481 5 102 2.35E-19 T 29-03-2018 CXR48_RS02945 796d836d7078542554605225385816fc 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.7E-31 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CXR48_RS18780 e576d4dd5376ebf610a8cf061a23dda7 385 Pfam PF00440 Bacterial regulatory proteins, tetR family 222 256 3.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS18780 e576d4dd5376ebf610a8cf061a23dda7 385 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 54 2.5E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS18780 e576d4dd5376ebf610a8cf061a23dda7 385 Gene3D G3DSA:1.10.10.60 6 43 5.1E-12 T 29-03-2018 CXR48_RS18780 e576d4dd5376ebf610a8cf061a23dda7 385 Gene3D G3DSA:1.10.10.60 44 202 2.3E-8 T 29-03-2018 CXR48_RS18780 e576d4dd5376ebf610a8cf061a23dda7 385 Gene3D G3DSA:1.10.10.60 246 358 5.4E-6 T 29-03-2018 CXR48_RS18780 e576d4dd5376ebf610a8cf061a23dda7 385 Gene3D G3DSA:1.10.10.60 203 245 1.1E-13 T 29-03-2018 CXR48_RS18780 e576d4dd5376ebf610a8cf061a23dda7 385 SUPERFAMILY SSF46689 7 72 4.39E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS18780 e576d4dd5376ebf610a8cf061a23dda7 385 SUPERFAMILY SSF46689 201 269 8.48E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS09825 defca5b2a7e5f25138f63f4f861c832c 423 Pfam PF00535 Glycosyl transferase family 2 6 168 1.5E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS09825 defca5b2a7e5f25138f63f4f861c832c 423 SUPERFAMILY SSF53448 4 221 8.91E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS09825 defca5b2a7e5f25138f63f4f861c832c 423 Gene3D G3DSA:3.90.550.10 4 286 1.0E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS14025 531adfd17f4cda12fbc23e4b6b549ad2 251 SMART SM00382 32 220 5.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS14025 531adfd17f4cda12fbc23e4b6b549ad2 251 SUPERFAMILY SSF52540 3 224 8.63E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14025 531adfd17f4cda12fbc23e4b6b549ad2 251 Gene3D G3DSA:3.40.50.300 2 230 5.4E-62 T 29-03-2018 CXR48_RS14025 531adfd17f4cda12fbc23e4b6b549ad2 251 Pfam PF00005 ABC transporter 23 171 8.1E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 Gene3D G3DSA:3.40.50.300 321 567 1.3E-62 T 29-03-2018 CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 Pfam PF00664 ABC transporter transmembrane region 16 276 4.0E-28 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 SMART SM00382 352 538 7.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 Pfam PF00005 ABC transporter 346 492 1.8E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 12 534 5.7E-173 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 SUPERFAMILY SSF90123 7 296 4.84E-50 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 SUPERFAMILY SSF90123 468 476 4.84E-50 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 SUPERFAMILY SSF52540 342 562 6.41E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS18380 e5f8076990b8b13d0b831341ac0c244f 567 Gene3D G3DSA:1.20.1560.10 5 314 7.2E-41 T 29-03-2018 CXR48_RS15065 d663a8f040afc893216fc45c6eeca020 352 TIGRFAM TIGR00260 thrC: threonine synthase 6 322 6.5E-113 T 29-03-2018 IPR004450 Threonine synthase-like CXR48_RS15065 d663a8f040afc893216fc45c6eeca020 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CXR48_RS15065 d663a8f040afc893216fc45c6eeca020 352 SUPERFAMILY SSF53686 4 346 3.93E-107 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS15065 d663a8f040afc893216fc45c6eeca020 352 PIRSF PIRSF038945 1 347 2.1E-162 T 29-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CXR48_RS15065 d663a8f040afc893216fc45c6eeca020 352 Gene3D G3DSA:3.40.50.1100 118 348 9.1E-56 T 29-03-2018 CXR48_RS15065 d663a8f040afc893216fc45c6eeca020 352 Gene3D G3DSA:3.40.50.1100 2 117 8.3E-22 T 29-03-2018 CXR48_RS15065 d663a8f040afc893216fc45c6eeca020 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 315 1.4E-76 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 SUPERFAMILY SSF52540 313 533 4.55E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 SMART SM00382 352 517 4.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 SMART SM00382 28 245 8.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 SUPERFAMILY SSF52540 4 234 6.94E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 Gene3D G3DSA:3.40.50.300 2 272 2.6E-54 T 29-03-2018 CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 Pfam PF00005 ABC transporter 343 473 5.5E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 Pfam PF00005 ABC transporter 19 191 4.1E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 Gene3D G3DSA:3.40.50.300 326 579 5.6E-57 T 29-03-2018 CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 Pfam PF16326 ABC transporter C-terminal domain 574 639 3.6E-13 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 Gene3D G3DSA:1.20.58.410 580 642 1.1E-7 T 29-03-2018 CXR48_RS03045 21f4f324de26a31d805c30944f28fa41 642 Pfam PF12848 ABC transporter 231 316 6.2E-25 T 29-03-2018 IPR032781 ABC-transporter extension domain CXR48_RS02900 01668cf7127ccf635b4b858243399b94 397 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 225 369 4.0E-17 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CXR48_RS02900 01668cf7127ccf635b4b858243399b94 397 Gene3D G3DSA:3.40.50.2000 232 376 2.9E-34 T 29-03-2018 CXR48_RS02900 01668cf7127ccf635b4b858243399b94 397 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 376 3.0E-92 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CXR48_RS02900 01668cf7127ccf635b4b858243399b94 397 SUPERFAMILY SSF53756 1 391 9.07E-72 T 29-03-2018 CXR48_RS02900 01668cf7127ccf635b4b858243399b94 397 Gene3D G3DSA:3.40.50.2000 4 231 9.2E-24 T 29-03-2018 CXR48_RS09605 492cbf5206c72ddc59f1a8b49ec0d14b 403 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 228 370 1.5E-14 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CXR48_RS09605 492cbf5206c72ddc59f1a8b49ec0d14b 403 SUPERFAMILY SSF53756 1 392 7.42E-74 T 29-03-2018 CXR48_RS09605 492cbf5206c72ddc59f1a8b49ec0d14b 403 Gene3D G3DSA:3.40.50.2000 3 236 2.3E-24 T 29-03-2018 CXR48_RS09605 492cbf5206c72ddc59f1a8b49ec0d14b 403 Gene3D G3DSA:3.40.50.2000 237 380 1.9E-36 T 29-03-2018 CXR48_RS09605 492cbf5206c72ddc59f1a8b49ec0d14b 403 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 393 3.2E-108 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CXR48_RS12055 f4dc8ebd209f2a0d64fa63f14e34d906 293 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 19 225 3.6E-62 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS12055 f4dc8ebd209f2a0d64fa63f14e34d906 293 PIRSF PIRSF006483 1 292 6.3E-89 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS12055 f4dc8ebd209f2a0d64fa63f14e34d906 293 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 8.9E-22 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CXR48_RS04525 4075dd7c30e1858a09cb5da0f3f8a9f3 305 SUPERFAMILY SSF52540 3 224 3.76E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04525 4075dd7c30e1858a09cb5da0f3f8a9f3 305 Gene3D G3DSA:3.40.50.300 1 250 5.1E-60 T 29-03-2018 CXR48_RS04525 4075dd7c30e1858a09cb5da0f3f8a9f3 305 SMART SM00382 29 209 5.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04525 4075dd7c30e1858a09cb5da0f3f8a9f3 305 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS04525 4075dd7c30e1858a09cb5da0f3f8a9f3 305 Pfam PF00005 ABC transporter 21 161 6.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 SUPERFAMILY SSF51735 10 274 8.29E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 4.5E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 4.5E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.5E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 Pfam PF00106 short chain dehydrogenase 12 215 4.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 7.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 7.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 7.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 235 255 7.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 7.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 7.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09030 d205d135dc3dd52bef0a5456e474392f 278 Gene3D G3DSA:3.40.50.720 2 275 7.6E-60 T 29-03-2018 CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 Gene3D G3DSA:3.40.50.920 542 664 2.0E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 5 338 8.8E-154 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 Pfam PF02780 Transketolase, C-terminal domain 548 657 2.3E-12 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 SMART SM00861 354 525 3.7E-71 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 666 0.0 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 1.7E-44 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 SUPERFAMILY SSF52518 341 527 2.24E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 SUPERFAMILY SSF52922 531 667 3.8E-41 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 Gene3D G3DSA:3.40.50.970 1 361 3.1E-111 T 29-03-2018 CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 Gene3D G3DSA:3.40.50.970 362 541 2.0E-42 T 29-03-2018 CXR48_RS08885 ab2fb475cceefaa79e518384b5f0fecb 667 SUPERFAMILY SSF52518 4 325 9.82E-118 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS06410 5fe5f7318554452d44f34fba4be6d0c5 323 Pfam PF00535 Glycosyl transferase family 2 8 170 7.3E-35 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS06410 5fe5f7318554452d44f34fba4be6d0c5 323 SUPERFAMILY SSF53448 6 227 6.03E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS06410 5fe5f7318554452d44f34fba4be6d0c5 323 Gene3D G3DSA:3.90.550.10 2 189 6.2E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS18425 f5edccb2f15ede051218cffa30fa96fc 338 Gene3D G3DSA:3.40.50.720 1 206 1.4E-44 T 29-03-2018 CXR48_RS18425 f5edccb2f15ede051218cffa30fa96fc 338 Gene3D G3DSA:3.90.25.10 250 336 1.5E-25 T 29-03-2018 CXR48_RS18425 f5edccb2f15ede051218cffa30fa96fc 338 Gene3D G3DSA:3.90.25.10 207 249 1.7E-10 T 29-03-2018 CXR48_RS18425 f5edccb2f15ede051218cffa30fa96fc 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 1.8E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS18425 f5edccb2f15ede051218cffa30fa96fc 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 2.9E-151 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CXR48_RS18425 f5edccb2f15ede051218cffa30fa96fc 338 SUPERFAMILY SSF51735 1 336 1.12E-103 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 501 638 1.1E-30 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 SUPERFAMILY SSF46785 2 64 4.08E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Gene3D G3DSA:3.40.50.2300 407 496 2.5E-17 T 29-03-2018 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 SUPERFAMILY SSF52794 409 487 5.23E-6 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Gene3D G3DSA:1.10.1790.10 284 402 1.9E-26 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Gene3D G3DSA:1.10.1790.10 164 283 4.9E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Gene3D G3DSA:1.10.10.10 2 67 1.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Gene3D G3DSA:1.10.10.10 88 154 3.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Pfam PF08279 HTH domain 5 63 1.8E-11 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 SUPERFAMILY SSF63520 298 402 1.57E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 SUPERFAMILY SSF63520 185 281 1.12E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Pfam PF05043 Mga helix-turn-helix domain 79 166 2.0E-18 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 SUPERFAMILY SSF55804 499 638 1.1E-29 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Pfam PF00874 PRD domain 203 281 1.5E-14 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Pfam PF00874 PRD domain 309 398 6.0E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CXR48_RS18280 652c8cb94ca8e47c44f24144c39fed30 651 Gene3D G3DSA:3.40.930.10 497 640 1.5E-30 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS10130 12c72e87c7fd08f0ad8e7198527a5733 295 Gene3D G3DSA:1.10.150.20 188 265 1.0E-24 T 29-03-2018 CXR48_RS10130 12c72e87c7fd08f0ad8e7198527a5733 295 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 170 5.8E-47 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CXR48_RS10130 12c72e87c7fd08f0ad8e7198527a5733 295 Gene3D G3DSA:3.40.50.1010 3 187 4.9E-59 T 29-03-2018 IPR029060 PIN domain-like CXR48_RS10130 12c72e87c7fd08f0ad8e7198527a5733 295 SUPERFAMILY SSF47807 174 286 1.64E-25 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CXR48_RS10130 12c72e87c7fd08f0ad8e7198527a5733 295 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 261 2.7E-26 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CXR48_RS10130 12c72e87c7fd08f0ad8e7198527a5733 295 SMART SM00475 3 264 5.7E-126 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CXR48_RS10130 12c72e87c7fd08f0ad8e7198527a5733 295 SMART SM00279 176 211 2.1E-16 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CXR48_RS10130 12c72e87c7fd08f0ad8e7198527a5733 295 SUPERFAMILY SSF88723 3 156 1.57E-44 T 29-03-2018 IPR029060 PIN domain-like CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 SMART SM00283 384 659 2.5E-90 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 Pfam PF02743 Cache domain 44 265 6.0E-24 T 29-03-2018 IPR033479 Double Cache domain 1 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 Pfam PF00672 HAMP domain 303 351 4.5E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 Gene3D G3DSA:1.10.287.950 298 407 1.4E-9 T 29-03-2018 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 Gene3D G3DSA:3.30.450.20 170 272 1.1E-13 T 29-03-2018 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 SUPERFAMILY SSF58104 390 658 1.28E-71 T 29-03-2018 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 SUPERFAMILY SSF58104 323 357 1.28E-71 T 29-03-2018 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 SMART SM00319 33 151 8.4E-15 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 Gene3D G3DSA:1.10.287.950 604 653 1.0E-4 T 29-03-2018 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 Gene3D G3DSA:1.10.287.950 408 603 2.8E-51 T 29-03-2018 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 Gene3D G3DSA:3.30.450.20 36 169 1.7E-22 T 29-03-2018 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 612 2.5E-54 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 SMART SM00304 303 355 1.0E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS14490 17818b9eb10fed120775d8f00bbd164c 668 SUPERFAMILY SSF103190 82 190 5.96E-10 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS12080 0788d24a1cb1ee263ea738695ed94f4a 314 Pfam PF02401 LytB protein 4 284 6.1E-82 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CXR48_RS12080 0788d24a1cb1ee263ea738695ed94f4a 314 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 33.184 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CXR48_RS12080 0788d24a1cb1ee263ea738695ed94f4a 314 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 286 6.4E-98 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CXR48_RS17780 2af055069d98eda6f1a6ad22330134da 91 Pfam PF03551 Transcriptional regulator PadR-like family 1 66 1.1E-18 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CXR48_RS17780 2af055069d98eda6f1a6ad22330134da 91 SUPERFAMILY SSF46785 1 87 5.77E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17780 2af055069d98eda6f1a6ad22330134da 91 Gene3D G3DSA:1.10.10.10 1 91 2.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 SUPERFAMILY SSF54814 182 297 4.45E-43 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 279 2.7E-118 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 Gene3D G3DSA:3.40.50.300 65 194 1.1E-16 T 29-03-2018 CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 Hamap MF_00367 GTPase Era [era]. 6 296 38.763 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 Pfam PF07650 KH domain 208 285 1.2E-21 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 Gene3D G3DSA:1.20.120.430 2 64 2.4E-16 T 29-03-2018 CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 SUPERFAMILY SSF52540 11 206 4.46E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 169 4.6E-28 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 Gene3D G3DSA:3.30.300.20 195 299 4.8E-47 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 2.8E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 2.8E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS12145 c39eabac4a63075a0ea24d8453ad6210 301 Pfam PF01926 50S ribosome-binding GTPase 11 125 2.7E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS15685 057e495e5f4f7d0421313883330bd895 671 Pfam PF00999 Sodium/hydrogen exchanger family 6 413 4.8E-66 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CXR48_RS15685 057e495e5f4f7d0421313883330bd895 671 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 11 525 9.5E-102 T 29-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 SMART SM00866 90 229 1.2E-30 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 Pfam PF07702 UTRA domain 91 229 4.3E-32 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 Gene3D G3DSA:3.40.1410.10 72 238 3.8E-31 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 SUPERFAMILY SSF64288 75 234 3.45E-40 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 SUPERFAMILY SSF46785 3 77 3.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 3.5E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 Gene3D G3DSA:1.10.10.10 1 69 1.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 5 236 3.8E-100 T 29-03-2018 IPR012770 Trehalose operon transcriptional repressor CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 SMART SM00345 9 68 4.2E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.8E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS03820 74146b6959de4ded3fc4d81da30c2c99 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.8E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS06010 588fe7fea6c1d22ef6107b95e35bcd29 189 Pfam PF14172 Domain of unknown function (DUF4309) 49 186 1.0E-27 T 29-03-2018 IPR025453 Protein of unknown function DUF4309 CXR48_RS09150 968a48eba6269c3fb32a2e115a0dc214 233 Pfam PF13500 AAA domain 2 209 1.3E-48 T 29-03-2018 CXR48_RS09150 968a48eba6269c3fb32a2e115a0dc214 233 SUPERFAMILY SSF52540 1 214 6.64E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS09150 968a48eba6269c3fb32a2e115a0dc214 233 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 172 7.9E-60 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CXR48_RS09150 968a48eba6269c3fb32a2e115a0dc214 233 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 208 29.575 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CXR48_RS09150 968a48eba6269c3fb32a2e115a0dc214 233 Gene3D G3DSA:3.40.50.300 1 218 1.5E-55 T 29-03-2018 CXR48_RS09150 968a48eba6269c3fb32a2e115a0dc214 233 PIRSF PIRSF006755 1 230 3.0E-72 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CXR48_RS01130 c0108cd7dcf7254ffbdaba0b24c631b7 230 Pfam PF04172 LrgB-like family 14 225 1.2E-70 T 29-03-2018 IPR007300 CidB/LrgB family CXR48_RS05200 6c1dd140dc0da00fab7b408c73c02377 236 Pfam PF15493 Domain of unknown function, YrpD 36 234 3.6E-83 T 29-03-2018 IPR029143 Protein of unknown function, YrpD CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 Pfam PF01134 Glucose inhibited division protein A 9 399 3.5E-170 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 3.9E-6 T 29-03-2018 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 3.9E-6 T 29-03-2018 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.37 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 Pfam PF13932 GidA associated domain 401 615 8.3E-80 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 Gene3D G3DSA:3.50.50.60 6 265 2.1E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 2.4E-299 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 SMART SM01228 545 616 1.0E-41 T 29-03-2018 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 SUPERFAMILY SSF51905 98 261 3.84E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS19410 97151fbca0919c5967dc7ead48a0043e 628 SUPERFAMILY SSF51905 7 67 3.84E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS02650 dbe69997d51c973a9c85a260fe0b468b 121 SUPERFAMILY SSF51182 3 107 2.17E-29 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS02650 dbe69997d51c973a9c85a260fe0b468b 121 Pfam PF07883 Cupin domain 35 93 4.4E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CXR48_RS02650 dbe69997d51c973a9c85a260fe0b468b 121 Gene3D G3DSA:2.60.120.10 1 106 1.2E-25 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS09160 1bb9d943d662975ec5c37f167b806b98 448 Gene3D G3DSA:3.40.640.10 182 325 6.5E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS09160 1bb9d943d662975ec5c37f167b806b98 448 SUPERFAMILY SSF53383 10 442 1.43E-126 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS09160 1bb9d943d662975ec5c37f167b806b98 448 Gene3D G3DSA:3.90.1150.10 326 447 1.7E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS09160 1bb9d943d662975ec5c37f167b806b98 448 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 443 53.127 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CXR48_RS09160 1bb9d943d662975ec5c37f167b806b98 448 Gene3D G3DSA:3.90.1150.10 1 176 8.3E-46 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS09160 1bb9d943d662975ec5c37f167b806b98 448 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 13 440 1.4E-168 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CXR48_RS09160 1bb9d943d662975ec5c37f167b806b98 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS09160 1bb9d943d662975ec5c37f167b806b98 448 Pfam PF00202 Aminotransferase class-III 23 440 7.1E-114 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS09160 1bb9d943d662975ec5c37f167b806b98 448 PIRSF PIRSF000521 19 443 2.6E-28 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 Gene3D G3DSA:2.40.37.10 287 437 2.1E-42 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 42.285 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 3.8E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 3.8E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 3.8E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 3.8E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 3.8E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 SUPERFAMILY SSF51419 30 299 2.91E-82 T 29-03-2018 IPR029066 PLP-binding barrel CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 296 4.0E-78 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 6.0E-31 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 6.0E-31 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 6.0E-31 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 6.0E-31 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 235 250 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 430 2.6E-164 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 63 81 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 33 388 8.6E-18 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 SUPERFAMILY SSF50621 273 431 2.3E-54 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CXR48_RS11080 6ca22f4c15aa7d2bc60d8af442b8653a 439 Gene3D G3DSA:3.20.20.10 39 286 4.6E-61 T 29-03-2018 IPR029066 PLP-binding barrel CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 Gene3D G3DSA:1.20.5.470 364 396 8.1E-10 T 29-03-2018 CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 SUPERFAMILY SSF52402 3 171 1.1E-48 T 29-03-2018 CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 Pfam PF00764 Arginosuccinate synthase 8 392 2.3E-184 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 SUPERFAMILY SSF69864 171 398 3.01E-94 T 29-03-2018 CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 397 54.95 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 Gene3D G3DSA:3.40.50.620 5 158 3.4E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 Gene3D G3DSA:3.90.1260.10 159 353 3.7E-84 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS13575 c7369ebcec9fa13e83b5109307336fcf 403 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 396 1.0E-180 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS09195 d3072605417825f54a4a83d110beeda0 299 Gene3D G3DSA:3.20.20.70 2 299 5.1E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS09195 d3072605417825f54a4a83d110beeda0 299 SUPERFAMILY SSF51569 2 292 7.77E-70 T 29-03-2018 CXR48_RS09195 d3072605417825f54a4a83d110beeda0 299 Pfam PF00682 HMGL-like 7 277 1.2E-49 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CXR48_RS12035 888257e422ce31f06570610e0b79b710 375 Pfam PF04551 GcpE protein 10 351 3.3E-141 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CXR48_RS12035 888257e422ce31f06570610e0b79b710 375 SUPERFAMILY SSF51717 15 214 2.59E-17 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CXR48_RS12035 888257e422ce31f06570610e0b79b710 375 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 1.2E-131 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CXR48_RS12035 888257e422ce31f06570610e0b79b710 375 Gene3D G3DSA:3.20.20.120 17 229 1.0E-21 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CXR48_RS12035 888257e422ce31f06570610e0b79b710 375 PIRSF PIRSF004640 1 361 2.1E-157 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CXR48_RS12035 888257e422ce31f06570610e0b79b710 375 SUPERFAMILY SSF56014 263 357 4.91E-14 T 29-03-2018 CXR48_RS12035 888257e422ce31f06570610e0b79b710 375 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 34.779 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CXR48_RS12840 64ccd2f529d9c3012c049808207c3249 180 PIRSF PIRSF037847 7 180 1.0E-66 T 29-03-2018 IPR026043 Transcription repressor NadR CXR48_RS12840 64ccd2f529d9c3012c049808207c3249 180 SUPERFAMILY SSF46785 10 66 5.97E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12840 64ccd2f529d9c3012c049808207c3249 180 Pfam PF02829 3H domain 81 177 3.9E-34 T 29-03-2018 IPR004173 3H domain GO:0036094 CXR48_RS12840 64ccd2f529d9c3012c049808207c3249 180 Gene3D G3DSA:1.10.10.10 2 87 1.3E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12840 64ccd2f529d9c3012c049808207c3249 180 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 85 175 8.0E-38 T 29-03-2018 IPR004173 3H domain GO:0036094 CXR48_RS12840 64ccd2f529d9c3012c049808207c3249 180 SUPERFAMILY SSF75500 77 179 9.29E-37 T 29-03-2018 IPR004173 3H domain GO:0036094 CXR48_RS12840 64ccd2f529d9c3012c049808207c3249 180 Pfam PF08279 HTH domain 12 64 3.0E-13 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CXR48_RS12840 64ccd2f529d9c3012c049808207c3249 180 Gene3D G3DSA:3.30.1340.20 88 178 7.5E-38 T 29-03-2018 IPR004173 3H domain GO:0036094 CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 Gene3D G3DSA:3.40.50.720 53 268 1.3E-59 T 29-03-2018 CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 Gene3D G3DSA:3.40.50.720 7 52 1.6E-12 T 29-03-2018 CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 266 1.5E-65 T 29-03-2018 CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 2.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 SUPERFAMILY SSF51735 13 267 4.64E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS19240 8953664500dfe9b3423fde28de253c84 268 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 15 268 7.8E-110 T 29-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CXR48_RS16360 eca4b54f9e1420fdbb4fcc9673114408 248 Gene3D G3DSA:3.30.2140.10 2 146 3.4E-21 T 29-03-2018 CXR48_RS16360 eca4b54f9e1420fdbb4fcc9673114408 248 Gene3D G3DSA:3.30.2140.10 147 248 4.2E-10 T 29-03-2018 CXR48_RS16360 eca4b54f9e1420fdbb4fcc9673114408 248 Pfam PF00797 N-acetyltransferase 22 246 2.6E-47 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CXR48_RS16360 eca4b54f9e1420fdbb4fcc9673114408 248 SUPERFAMILY SSF54001 2 247 7.6E-57 T 29-03-2018 CXR48_RS16910 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 118 132 3.9E-48 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CXR48_RS16910 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 20 37 3.9E-48 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CXR48_RS16910 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 88 101 3.9E-48 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CXR48_RS16910 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 66 80 3.9E-48 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CXR48_RS16910 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 2 17 3.9E-48 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CXR48_RS16910 f8037460b48bd451efa2a1342b22bf15 149 TIGRFAM TIGR04011 poly_gGlu_PgsC: poly-gamma-glutamate biosynthesis protein PgsC 10 139 8.5E-44 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CXR48_RS16910 f8037460b48bd451efa2a1342b22bf15 149 Pfam PF14102 Capsule biosynthesis CapC 12 128 3.2E-39 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 6.5E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 6.5E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 6.5E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 6.5E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 Gene3D G3DSA:1.10.1270.10 155 239 3.8E-21 T 29-03-2018 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 Gene3D G3DSA:1.10.601.10 32 130 6.9E-31 T 29-03-2018 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 8 239 1.3E-133 T 29-03-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 Pfam PF04542 Sigma-70 region 2 62 131 1.8E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 Pfam PF04545 Sigma-70, region 4 180 233 3.9E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 4.0E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 SUPERFAMILY SSF88946 18 131 3.66E-35 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 PIRSF PIRSF000770 1 239 6.0E-81 T 29-03-2018 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 SUPERFAMILY SSF88659 143 237 3.36E-22 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07625 5aee90b3aca5630df60bbd130f56d3cb 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 Gene3D G3DSA:3.40.50.2300 171 297 3.6E-11 T 29-03-2018 CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.6E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 Gene3D G3DSA:3.40.50.2300 55 170 2.0E-19 T 29-03-2018 CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 SUPERFAMILY SSF47413 1 60 2.44E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 Gene3D G3DSA:1.10.260.40 3 54 5.6E-20 T 29-03-2018 CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 279 1.2E-44 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.5E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.5E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 SUPERFAMILY SSF53822 58 294 2.16E-37 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS19325 35d94c157cd16edba98e7037ab7c4cb8 312 SMART SM00354 1 71 6.6E-36 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS02395 87a0110dbcef09efcb15493454f77c02 159 Pfam PF03703 Bacterial PH domain 73 148 7.5E-17 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CXR48_RS16145 d79b24879c23e99ff0db95cacfa2931d 215 Gene3D G3DSA:2.160.10.10 89 215 1.3E-26 T 29-03-2018 CXR48_RS16145 d79b24879c23e99ff0db95cacfa2931d 215 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 165 193 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CXR48_RS16145 d79b24879c23e99ff0db95cacfa2931d 215 Gene3D G3DSA:3.40.50.20 1 88 9.5E-8 T 29-03-2018 CXR48_RS16145 d79b24879c23e99ff0db95cacfa2931d 215 SUPERFAMILY SSF51161 2 210 8.32E-42 T 29-03-2018 IPR011004 Trimeric LpxA-like CXR48_RS16145 d79b24879c23e99ff0db95cacfa2931d 215 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 3 205 3.6E-60 T 29-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CXR48_RS16145 d79b24879c23e99ff0db95cacfa2931d 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 134 3.4E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS16145 d79b24879c23e99ff0db95cacfa2931d 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 141 166 7.6E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS05045 03641d7b57156cfc1fa3fcc33bd110dd 713 SUPERFAMILY SSF53955 44 253 1.12E-74 T 29-03-2018 IPR023346 Lysozyme-like domain CXR48_RS05045 03641d7b57156cfc1fa3fcc33bd110dd 713 Pfam PF00905 Penicillin binding protein transpeptidase domain 321 593 2.7E-44 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS05045 03641d7b57156cfc1fa3fcc33bd110dd 713 SUPERFAMILY SSF56601 262 611 1.59E-105 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS05045 03641d7b57156cfc1fa3fcc33bd110dd 713 SUPERFAMILY SSF56601 211 233 1.59E-105 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS05045 03641d7b57156cfc1fa3fcc33bd110dd 713 Gene3D G3DSA:1.10.3810.10 47 246 2.0E-81 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CXR48_RS05045 03641d7b57156cfc1fa3fcc33bd110dd 713 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 65 597 1.6E-182 T 29-03-2018 CXR48_RS05045 03641d7b57156cfc1fa3fcc33bd110dd 713 Gene3D G3DSA:3.40.710.10 249 625 2.0E-97 T 29-03-2018 CXR48_RS05045 03641d7b57156cfc1fa3fcc33bd110dd 713 Pfam PF00912 Transglycosylase 55 229 6.4E-66 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CXR48_RS16410 301e8edb1b89122eb568a47b7b8eb1fe 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 1.9E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS16410 301e8edb1b89122eb568a47b7b8eb1fe 225 SMART SM00862 146 221 5.0E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS16410 301e8edb1b89122eb568a47b7b8eb1fe 225 Gene3D G3DSA:1.10.10.10 125 225 6.9E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16410 301e8edb1b89122eb568a47b7b8eb1fe 225 Gene3D G3DSA:3.40.50.2300 2 124 1.8E-38 T 29-03-2018 CXR48_RS16410 301e8edb1b89122eb568a47b7b8eb1fe 225 Pfam PF00072 Response regulator receiver domain 4 112 4.1E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS16410 301e8edb1b89122eb568a47b7b8eb1fe 225 SMART SM00448 2 112 4.5E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS16410 301e8edb1b89122eb568a47b7b8eb1fe 225 SUPERFAMILY SSF52172 3 153 1.71E-42 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS16410 301e8edb1b89122eb568a47b7b8eb1fe 225 SUPERFAMILY SSF46894 121 222 3.68E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 Gene3D G3DSA:4.10.640.10 3 79 4.0E-35 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 2.8E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 2.8E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 2.8E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 2.8E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 7 78 22.443 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 77 1.7E-37 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 76 9.0E-23 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 Pfam PF01084 Ribosomal protein S18 23 73 3.2E-28 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19345 cd15e0b730edf60671567640d8cacc7f 79 SUPERFAMILY SSF46911 6 78 4.05E-31 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 310 413 2.1E-22 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 1.4E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 1.4E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 1.4E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 34 287 3.7E-84 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 Gene3D G3DSA:3.40.710.10 28 309 5.1E-48 T 29-03-2018 CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 SMART SM00936 310 413 4.3E-25 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 Gene3D G3DSA:2.60.410.10 312 413 6.1E-23 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 SUPERFAMILY SSF56601 13 307 3.18E-75 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS00075 02af80620a83431e0689ce287f1f7cbc 443 SUPERFAMILY SSF69189 301 391 1.84E-19 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 Gene3D G3DSA:3.40.50.720 145 349 6.2E-39 T 29-03-2018 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 22 131 7.6E-28 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 SUPERFAMILY SSF51735 141 348 9.54E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 1.7E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 1.7E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 1.7E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 1.7E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 Gene3D G3DSA:3.40.50.10860 1 144 3.4E-55 T 29-03-2018 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 SMART SM00839 144 351 9.1E-72 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 SUPERFAMILY SSF53223 4 143 1.15E-49 T 29-03-2018 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 PIRSF PIRSF000188 1 353 9.6E-167 T 29-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 218 298 4.0E-9 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS11535 059423c5db6e54667b4aafd9afc37167 364 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 148 200 1.5E-6 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CXR48_RS06905 a50aae4f9d24c27c43bfa9e8c1bc48cf 258 Pfam PF00188 Cysteine-rich secretory protein family 143 254 5.9E-23 T 29-03-2018 IPR014044 CAP domain CXR48_RS06905 a50aae4f9d24c27c43bfa9e8c1bc48cf 258 Gene3D G3DSA:3.40.33.10 129 255 1.1E-21 T 29-03-2018 IPR014044 CAP domain CXR48_RS06905 a50aae4f9d24c27c43bfa9e8c1bc48cf 258 SUPERFAMILY SSF55797 135 254 7.85E-26 T 29-03-2018 IPR014044 CAP domain CXR48_RS06905 a50aae4f9d24c27c43bfa9e8c1bc48cf 258 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 135 257 1.3E-61 T 29-03-2018 IPR014258 CAP domain, YkwD-like CXR48_RS18720 1605a1ecfb5e7fab3d0beaefe8fd4d07 330 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 265 278 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CXR48_RS18720 1605a1ecfb5e7fab3d0beaefe8fd4d07 330 Pfam PF00294 pfkB family carbohydrate kinase 12 313 4.3E-67 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CXR48_RS18720 1605a1ecfb5e7fab3d0beaefe8fd4d07 330 Hamap MF_01668 5-dehydro-2-deoxygluconokinase [iolC]. 7 325 55.328 T 29-03-2018 IPR022841 5-dehydro-2-deoxygluconokinase, Firmicutes GO:0016310|GO:0047590 KEGG: 00562+2.7.1.92 CXR48_RS18720 1605a1ecfb5e7fab3d0beaefe8fd4d07 330 SUPERFAMILY SSF53613 10 321 1.51E-73 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS18720 1605a1ecfb5e7fab3d0beaefe8fd4d07 330 Gene3D G3DSA:2.20.150.10 21 44 1.4E-14 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CXR48_RS18720 1605a1ecfb5e7fab3d0beaefe8fd4d07 330 Gene3D G3DSA:3.40.1190.20 45 329 1.8E-54 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS18720 1605a1ecfb5e7fab3d0beaefe8fd4d07 330 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 11 320 3.8E-119 T 29-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 CXR48_RS13880 b1ec8303d0a3194a512017b6236ad764 265 Pfam PF01636 Phosphotransferase enzyme family 17 228 1.5E-22 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CXR48_RS13880 b1ec8303d0a3194a512017b6236ad764 265 Gene3D G3DSA:3.90.1200.10 30 263 8.3E-21 T 29-03-2018 CXR48_RS13880 b1ec8303d0a3194a512017b6236ad764 265 SUPERFAMILY SSF56112 2 229 3.46E-33 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS07735 cd0acdc8fda8822dc2053bc550066bbe 256 Gene3D G3DSA:2.10.240.10 215 255 1.8E-18 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CXR48_RS07735 cd0acdc8fda8822dc2053bc550066bbe 256 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 3 256 38.446 T 29-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit CXR48_RS07735 cd0acdc8fda8822dc2053bc550066bbe 256 Pfam PF00175 Oxidoreductase NAD-binding domain 112 202 7.5E-6 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CXR48_RS07735 cd0acdc8fda8822dc2053bc550066bbe 256 Gene3D G3DSA:3.40.50.80 101 207 5.4E-11 T 29-03-2018 CXR48_RS07735 cd0acdc8fda8822dc2053bc550066bbe 256 SUPERFAMILY SSF63380 3 99 2.15E-20 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CXR48_RS07735 cd0acdc8fda8822dc2053bc550066bbe 256 PIRSF PIRSF006816 1 256 5.2E-70 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CXR48_RS07735 cd0acdc8fda8822dc2053bc550066bbe 256 SUPERFAMILY SSF52343 94 255 7.2E-33 T 29-03-2018 CXR48_RS07735 cd0acdc8fda8822dc2053bc550066bbe 256 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 215 254 1.3E-16 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CXR48_RS07735 cd0acdc8fda8822dc2053bc550066bbe 256 Gene3D G3DSA:2.40.30.10 1 97 6.7E-12 T 29-03-2018 CXR48_RS02915 a29b3298836a7bf69f6c84f620b355d4 452 Gene3D G3DSA:3.40.710.10 1 353 1.9E-75 T 29-03-2018 CXR48_RS02915 a29b3298836a7bf69f6c84f620b355d4 452 Pfam PF00144 Beta-lactamase 9 337 2.1E-59 T 29-03-2018 IPR001466 Beta-lactamase-related CXR48_RS02915 a29b3298836a7bf69f6c84f620b355d4 452 SUPERFAMILY SSF56601 8 332 4.81E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS12220 2da31c5114fdb3c9761ffc1093c0dff0 256 Pfam PF04452 RNA methyltransferase 20 247 5.5E-76 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS12220 2da31c5114fdb3c9761ffc1093c0dff0 256 SUPERFAMILY SSF75217 74 251 2.01E-54 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CXR48_RS12220 2da31c5114fdb3c9761ffc1093c0dff0 256 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 251 9.3E-83 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS12220 2da31c5114fdb3c9761ffc1093c0dff0 256 PIRSF PIRSF015601 1 251 2.1E-64 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS12220 2da31c5114fdb3c9761ffc1093c0dff0 256 Gene3D G3DSA:3.40.1280.10 1 256 2.2E-80 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CXR48_RS12220 2da31c5114fdb3c9761ffc1093c0dff0 256 SUPERFAMILY SSF88697 2 71 1.17E-15 T 29-03-2018 IPR015947 PUA-like domain CXR48_RS07500 9f56863b0b493a0017d5273378fd4269 259 Gene3D G3DSA:3.40.1090.10 2 257 3.6E-44 T 29-03-2018 CXR48_RS07500 9f56863b0b493a0017d5273378fd4269 259 Pfam PF01734 Patatin-like phospholipase 8 164 1.2E-22 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CXR48_RS07500 9f56863b0b493a0017d5273378fd4269 259 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 11 43 - T 29-03-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 CXR48_RS07500 9f56863b0b493a0017d5273378fd4269 259 SUPERFAMILY SSF52151 3 251 1.44E-55 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS03785 a1a34ca6f30fe6684fbc31604b08657a 645 Gene3D G3DSA:3.40.720.10 237 546 1.0E-42 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CXR48_RS03785 a1a34ca6f30fe6684fbc31604b08657a 645 SUPERFAMILY SSF53649 243 635 1.03E-76 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CXR48_RS03785 a1a34ca6f30fe6684fbc31604b08657a 645 PIRSF PIRSF005091 1 620 6.2E-187 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like CXR48_RS03785 a1a34ca6f30fe6684fbc31604b08657a 645 Pfam PF00884 Sulfatase 245 536 4.2E-45 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CXR48_RS12625 003709c1c6802576a56379e099e9742a 242 SUPERFAMILY SSF52540 1 234 3.14E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12625 003709c1c6802576a56379e099e9742a 242 Gene3D G3DSA:3.40.50.300 1 240 5.3E-77 T 29-03-2018 CXR48_RS12625 003709c1c6802576a56379e099e9742a 242 Pfam PF00005 ABC transporter 17 165 9.8E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS12625 003709c1c6802576a56379e099e9742a 242 SMART SM00382 26 213 9.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS12625 003709c1c6802576a56379e099e9742a 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS12625 003709c1c6802576a56379e099e9742a 242 PIRSF PIRSF039085 1 241 7.6E-117 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CXR48_RS15270 39187295f07d59f46f328c767cc78e78 406 Gene3D G3DSA:3.90.1150.10 281 398 2.0E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS15270 39187295f07d59f46f328c767cc78e78 406 SUPERFAMILY SSF53383 2 398 5.38E-134 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS15270 39187295f07d59f46f328c767cc78e78 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 402 1.1E-193 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CXR48_RS15270 39187295f07d59f46f328c767cc78e78 406 Pfam PF00266 Aminotransferase class-V 23 391 7.7E-165 T 29-03-2018 IPR000192 Aminotransferase class V domain CXR48_RS15270 39187295f07d59f46f328c767cc78e78 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CXR48_RS15270 39187295f07d59f46f328c767cc78e78 406 Gene3D G3DSA:3.40.640.10 32 280 9.5E-64 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS15270 39187295f07d59f46f328c767cc78e78 406 PIRSF PIRSF005572 20 404 3.3E-50 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CXR48_RS02925 b5fd213b58528daa6e653f06bcbc14e4 386 Gene3D G3DSA:1.20.1250.20 193 386 3.5E-21 T 29-03-2018 CXR48_RS02925 b5fd213b58528daa6e653f06bcbc14e4 386 Pfam PF07690 Major Facilitator Superfamily 10 320 1.0E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS02925 b5fd213b58528daa6e653f06bcbc14e4 386 SUPERFAMILY SSF103473 5 379 8.89E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS02925 b5fd213b58528daa6e653f06bcbc14e4 386 Gene3D G3DSA:1.20.1250.20 1 192 3.0E-27 T 29-03-2018 CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 11 358 1.6E-142 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 Pfam PF13167 GTP-binding GTPase N-terminal 27 115 8.2E-34 T 29-03-2018 IPR025121 GTPase HflX, N-terminal CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 Hamap MF_00900 GTPase HflX [hflX]. 30 389 47.037 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 PIRSF PIRSF006809 1 420 8.5E-144 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 Gene3D G3DSA:3.40.50.300 174 233 4.7E-9 T 29-03-2018 CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 Pfam PF16360 GTP-binding GTPase Middle Region 117 195 1.0E-30 T 29-03-2018 IPR032305 GTP-binding protein, middle domain CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 SUPERFAMILY SSF52540 201 363 1.1E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 Gene3D G3DSA:3.40.50.300 234 381 3.6E-13 T 29-03-2018 CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 203 223 2.0E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 270 288 2.0E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS08700 f24453a7040e7fe306066a2f263babbe 420 Pfam PF01926 50S ribosome-binding GTPase 203 321 3.7E-18 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS14965 189a02cb6ddf912807e4b4834d82a162 326 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 165 177 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CXR48_RS14965 189a02cb6ddf912807e4b4834d82a162 326 PIRSF PIRSF036500 1 326 1.3E-195 T 29-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CXR48_RS14965 189a02cb6ddf912807e4b4834d82a162 326 SMART SM01240 3 326 3.4E-117 T 29-03-2018 CXR48_RS14965 189a02cb6ddf912807e4b4834d82a162 326 SUPERFAMILY SSF51412 4 315 1.13E-93 T 29-03-2018 CXR48_RS14965 189a02cb6ddf912807e4b4834d82a162 326 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 4 324 1.9E-199 T 29-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CXR48_RS14965 189a02cb6ddf912807e4b4834d82a162 326 Hamap MF_01511 GMP reductase [guaC]. 2 325 64.675 T 29-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CXR48_RS14965 189a02cb6ddf912807e4b4834d82a162 326 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 6 310 4.3E-71 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CXR48_RS14965 189a02cb6ddf912807e4b4834d82a162 326 Gene3D G3DSA:3.20.20.70 1 325 1.1E-72 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS17710 e067b57c406ac282121bd86ddb08720c 290 TIGRFAM TIGR01230 agmatinase: agmatinase 10 286 1.4E-122 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CXR48_RS17710 e067b57c406ac282121bd86ddb08720c 290 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CXR48_RS17710 e067b57c406ac282121bd86ddb08720c 290 Gene3D G3DSA:3.40.800.10 16 290 9.8E-85 T 29-03-2018 CXR48_RS17710 e067b57c406ac282121bd86ddb08720c 290 PIRSF PIRSF036979 1 290 3.7E-95 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS17710 e067b57c406ac282121bd86ddb08720c 290 Pfam PF00491 Arginase family 22 285 2.2E-79 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS17710 e067b57c406ac282121bd86ddb08720c 290 SUPERFAMILY SSF52768 14 288 1.98E-86 T 29-03-2018 CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 1 406 8.6E-217 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 Gene3D G3DSA:3.40.50.300 53 309 8.8E-71 T 29-03-2018 CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 SMART SM00994 10 49 8.0E-24 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 SMART SM01086 311 407 1.3E-32 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 53.457 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 SUPERFAMILY SSF57716 11 46 1.71E-11 T 29-03-2018 CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 2.7E-51 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 SUPERFAMILY SSF52540 59 392 7.36E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 Pfam PF06689 ClpX C4-type zinc finger 12 48 2.6E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 1.3E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 SMART SM00382 108 259 3.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS13010 421d251cd3d420e129b6b2bc2ef70c95 420 Gene3D G3DSA:1.10.8.60 311 401 6.3E-32 T 29-03-2018 CXR48_RS12465 d87f9e7e75227ea82a1783bafd2b2286 305 PIRSF PIRSF038896 2 305 3.9E-96 T 29-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 CXR48_RS12465 d87f9e7e75227ea82a1783bafd2b2286 305 SUPERFAMILY SSF56281 57 268 1.57E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS12465 d87f9e7e75227ea82a1783bafd2b2286 305 SMART SM00849 62 262 2.0E-4 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS12465 d87f9e7e75227ea82a1783bafd2b2286 305 Pfam PF12706 Beta-lactamase superfamily domain 74 263 3.7E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS12465 d87f9e7e75227ea82a1783bafd2b2286 305 Gene3D G3DSA:3.60.15.10 19 305 8.0E-56 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS08915 1176cac99a8f0a1e6ae1230e55b2bb8c 163 Pfam PF07301 Protein of unknown function (DUF1453) 8 151 4.7E-58 T 29-03-2018 IPR009916 Protein of unknown function DUF1453 CXR48_RS08915 1176cac99a8f0a1e6ae1230e55b2bb8c 163 PIRSF PIRSF021441 1 162 1.5E-68 T 29-03-2018 IPR031306 CcdC protein CXR48_RS16475 c287050e7d7361f04b7453e087bfbb9d 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 74 178 7.4E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS16475 c287050e7d7361f04b7453e087bfbb9d 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 73 184 1.9E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS16475 c287050e7d7361f04b7453e087bfbb9d 216 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 4 216 43.546 T 29-03-2018 IPR023733 Pyrophosphatase PpaX GO:0008152|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CXR48_RS16475 c287050e7d7361f04b7453e087bfbb9d 216 SUPERFAMILY SSF56784 5 212 5.34E-58 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS16475 c287050e7d7361f04b7453e087bfbb9d 216 Gene3D G3DSA:3.40.50.1000 76 214 7.0E-33 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS16475 c287050e7d7361f04b7453e087bfbb9d 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 184 7.5E-56 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS16475 c287050e7d7361f04b7453e087bfbb9d 216 Gene3D G3DSA:1.10.150.240 32 75 2.3E-13 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CXR48_RS16475 c287050e7d7361f04b7453e087bfbb9d 216 Gene3D G3DSA:3.40.50.1000 2 31 0.017 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS09110 43f3be7bd7f040cb17de0f69aeb20bc0 400 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 323 6.0E-40 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CXR48_RS09110 43f3be7bd7f040cb17de0f69aeb20bc0 400 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 4 290 2.0E-97 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS09110 43f3be7bd7f040cb17de0f69aeb20bc0 400 Gene3D G3DSA:3.40.366.10 188 309 3.9E-25 T 29-03-2018 CXR48_RS09110 43f3be7bd7f040cb17de0f69aeb20bc0 400 SUPERFAMILY SSF52151 190 305 2.28E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS09110 43f3be7bd7f040cb17de0f69aeb20bc0 400 SUPERFAMILY SSF52151 4 122 2.28E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS09110 43f3be7bd7f040cb17de0f69aeb20bc0 400 Pfam PF00698 Acyl transferase domain 6 291 1.0E-34 T 29-03-2018 IPR014043 Acyl transferase CXR48_RS09110 43f3be7bd7f040cb17de0f69aeb20bc0 400 SUPERFAMILY SSF55048 129 197 1.44E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CXR48_RS09110 43f3be7bd7f040cb17de0f69aeb20bc0 400 Gene3D G3DSA:3.30.70.250 144 187 7.6E-16 T 29-03-2018 CXR48_RS09110 43f3be7bd7f040cb17de0f69aeb20bc0 400 Gene3D G3DSA:3.40.366.10 1 143 5.0E-39 T 29-03-2018 CXR48_RS18215 c9ee5be5521bac7a4b1a31a28d5eada5 210 Gene3D G3DSA:1.10.287.860 163 210 4.0E-17 T 29-03-2018 CXR48_RS18215 c9ee5be5521bac7a4b1a31a28d5eada5 210 SUPERFAMILY SSF81301 18 208 1.13E-57 T 29-03-2018 CXR48_RS18215 c9ee5be5521bac7a4b1a31a28d5eada5 210 Pfam PF04607 Region found in RelA / SpoT proteins 57 178 2.0E-38 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CXR48_RS18215 c9ee5be5521bac7a4b1a31a28d5eada5 210 SMART SM00954 57 180 1.8E-46 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CXR48_RS18215 c9ee5be5521bac7a4b1a31a28d5eada5 210 Gene3D G3DSA:3.30.460.10 7 161 7.0E-40 T 29-03-2018 CXR48_RS15460 819a587a456333fba83128e849543af5 462 SUPERFAMILY SSF48557 2 458 2.67E-156 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CXR48_RS15460 819a587a456333fba83128e849543af5 462 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 1.3E-34 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS15460 819a587a456333fba83128e849543af5 462 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 1.3E-34 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS15460 819a587a456333fba83128e849543af5 462 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 1.3E-34 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS15460 819a587a456333fba83128e849543af5 462 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 1.3E-34 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS15460 819a587a456333fba83128e849543af5 462 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 1.3E-5 T 29-03-2018 CXR48_RS15460 819a587a456333fba83128e849543af5 462 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 1.3E-5 T 29-03-2018 CXR48_RS15460 819a587a456333fba83128e849543af5 462 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 90.004 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS15460 819a587a456333fba83128e849543af5 462 Gene3D G3DSA:1.10.275.10 1 136 2.0E-61 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CXR48_RS15460 819a587a456333fba83128e849543af5 462 Pfam PF10415 Fumarase C C-terminus 406 459 1.3E-26 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS15460 819a587a456333fba83128e849543af5 462 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 458 4.5E-251 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CXR48_RS15460 819a587a456333fba83128e849543af5 462 Gene3D G3DSA:1.20.200.10 137 415 2.1E-90 T 29-03-2018 CXR48_RS15460 819a587a456333fba83128e849543af5 462 Gene3D G3DSA:1.10.40.30 416 460 3.1E-27 T 29-03-2018 CXR48_RS15460 819a587a456333fba83128e849543af5 462 Pfam PF00206 Lyase 11 340 3.1E-121 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CXR48_RS15460 819a587a456333fba83128e849543af5 462 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 Pfam PF00158 Sigma-54 interaction domain 143 308 5.7E-62 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 SUPERFAMILY SSF46689 355 458 6.09E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 SUPERFAMILY SSF55785 12 114 9.9E-9 T 29-03-2018 IPR000014 PAS domain CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 Gene3D G3DSA:3.30.450.20 12 124 2.3E-10 T 29-03-2018 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 438 458 5.6E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 421 438 5.6E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 Gene3D G3DSA:3.40.50.300 138 314 1.8E-28 T 29-03-2018 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 125 1.3E-8 T 29-03-2018 IPR000014 PAS domain CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 SMART SM00382 163 305 1.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 Gene3D G3DSA:1.10.10.60 374 458 3.9E-21 T 29-03-2018 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 Gene3D G3DSA:1.10.8.60 315 373 3.2E-20 T 29-03-2018 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 Pfam PF02954 Bacterial regulatory protein, Fis family 415 455 1.6E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 SUPERFAMILY SSF52540 143 385 2.66E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18965 cea81a7f69d758a2c0cda30e2d8e3805 461 Pfam PF13426 PAS domain 22 121 5.8E-8 T 29-03-2018 IPR000014 PAS domain CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 Pfam PF01018 GTP1/OBG 3 157 1.2E-61 T 29-03-2018 IPR006169 GTP1/OBG domain CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 Gene3D G3DSA:3.40.50.300 189 347 1.3E-29 T 29-03-2018 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 Pfam PF09269 Domain of unknown function (DUF1967) 358 426 2.2E-24 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 Gene3D G3DSA:2.70.210.12 1 151 1.2E-60 T 29-03-2018 IPR006169 GTP1/OBG domain CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 426 9.3E-26 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 Gene3D G3DSA:3.40.50.300 152 188 0.0062 T 29-03-2018 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 4.7E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 4.7E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 4.7E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 4.7E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 4.1E-13 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 Pfam PF01926 50S ribosome-binding GTPase 160 283 1.1E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 SUPERFAMILY SSF102741 356 428 9.55E-24 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 PIRSF PIRSF002401 1 375 3.5E-146 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 8.3E-146 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 SUPERFAMILY SSF52540 151 330 4.06E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 Hamap MF_01454 GTPase Obg [obg]. 1 329 48.847 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CXR48_RS12855 3acfe1d1ba7a27de4ac8d29c94466b93 428 SUPERFAMILY SSF82051 1 157 4.05E-57 T 29-03-2018 IPR006169 GTP1/OBG domain CXR48_RS08190 40f5d5d37c7ab3ee0cf08709c986bf60 355 PIRSF PIRSF000876 1 355 9.5E-133 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CXR48_RS08190 40f5d5d37c7ab3ee0cf08709c986bf60 355 Gene3D G3DSA:3.40.50.180 169 355 3.3E-68 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CXR48_RS08190 40f5d5d37c7ab3ee0cf08709c986bf60 355 SUPERFAMILY SSF52172 2 108 1.08E-29 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS08190 40f5d5d37c7ab3ee0cf08709c986bf60 355 Pfam PF00072 Response regulator receiver domain 4 109 9.3E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS08190 40f5d5d37c7ab3ee0cf08709c986bf60 355 Gene3D G3DSA:3.40.50.2300 1 168 2.1E-31 T 29-03-2018 CXR48_RS08190 40f5d5d37c7ab3ee0cf08709c986bf60 355 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 2 351 38.093 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CXR48_RS08190 40f5d5d37c7ab3ee0cf08709c986bf60 355 SUPERFAMILY SSF52738 162 351 1.05E-60 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CXR48_RS08190 40f5d5d37c7ab3ee0cf08709c986bf60 355 SMART SM00448 2 125 5.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS08190 40f5d5d37c7ab3ee0cf08709c986bf60 355 Pfam PF01339 CheB methylesterase 166 346 6.8E-56 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CXR48_RS15555 072133a5a6a1476fae19e6d61fc8538b 239 Gene3D G3DSA:3.40.50.2300 1 125 5.4E-36 T 29-03-2018 CXR48_RS15555 072133a5a6a1476fae19e6d61fc8538b 239 Pfam PF00072 Response regulator receiver domain 6 115 2.9E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS15555 072133a5a6a1476fae19e6d61fc8538b 239 SMART SM00448 4 115 7.3E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS15555 072133a5a6a1476fae19e6d61fc8538b 239 Gene3D G3DSA:1.10.10.10 126 235 3.1E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15555 072133a5a6a1476fae19e6d61fc8538b 239 SUPERFAMILY SSF46894 132 230 2.1E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS15555 072133a5a6a1476fae19e6d61fc8538b 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 6.4E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS15555 072133a5a6a1476fae19e6d61fc8538b 239 SUPERFAMILY SSF52172 3 137 2.7E-38 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS15555 072133a5a6a1476fae19e6d61fc8538b 239 SMART SM00862 152 228 1.9E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS06805 5564e826291197845aee50abcf734317 146 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 110 1.6E-28 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CXR48_RS06805 5564e826291197845aee50abcf734317 146 SUPERFAMILY SSF55620 11 139 2.5E-32 T 29-03-2018 CXR48_RS06805 5564e826291197845aee50abcf734317 146 Gene3D G3DSA:3.30.479.10 3 141 5.7E-34 T 29-03-2018 CXR48_RS06805 5564e826291197845aee50abcf734317 146 TIGRFAM TIGR00039 6PTHBS: 6-pyruvoyl tetrahydropterin synthase/QueD family protein 15 141 1.4E-40 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CXR48_RS06805 5564e826291197845aee50abcf734317 146 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 138 3.4E-28 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CXR48_RS06805 5564e826291197845aee50abcf734317 146 PIRSF PIRSF006113 13 140 9.7E-20 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 Pfam PF00390 Malic enzyme, N-terminal domain 82 263 1.1E-71 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 SUPERFAMILY SSF53223 4 272 5.68E-102 T 29-03-2018 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 PRINTS PR00072 Malic enzyme signature 185 207 2.5E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 PRINTS PR00072 Malic enzyme signature 88 112 2.5E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 PRINTS PR00072 Malic enzyme signature 412 428 2.5E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 PRINTS PR00072 Malic enzyme signature 149 178 2.5E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 PRINTS PR00072 Malic enzyme signature 269 285 2.5E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 PRINTS PR00072 Malic enzyme signature 244 262 2.5E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 PRINTS PR00072 Malic enzyme signature 300 316 2.5E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 Gene3D G3DSA:3.40.50.720 271 565 9.9E-109 T 29-03-2018 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 PIRSF PIRSF000106 2 565 1.6E-220 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 SMART SM00919 273 534 1.6E-127 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 ProSitePatterns PS00331 Malic enzymes signature. 269 285 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 SMART SM01274 82 263 5.9E-94 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 SUPERFAMILY SSF51735 273 563 5.91E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 Gene3D G3DSA:3.40.50.10380 16 270 1.5E-103 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS13860 0f43a5cfc546c49942ee38a70a722c33 565 Pfam PF03949 Malic enzyme, NAD binding domain 273 534 1.7E-105 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 SUPERFAMILY SSF54719 159 274 2.1E-41 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 SUPERFAMILY SSF46609 74 161 5.63E-31 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 167 269 2.6E-34 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 PRINTS PR01703 Manganese superoxide dismutase signature 83 94 7.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 PRINTS PR01703 Manganese superoxide dismutase signature 196 204 7.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 PRINTS PR01703 Manganese superoxide dismutase signature 143 156 7.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 PRINTS PR01703 Manganese superoxide dismutase signature 234 246 7.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 PRINTS PR01703 Manganese superoxide dismutase signature 104 117 7.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 236 243 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 Gene3D G3DSA:1.10.287.990 97 160 1.5E-18 T 29-03-2018 CXR48_RS09555 a06fb7fc1c1fcb9835a6ca9a11992858 281 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 79 159 1.1E-26 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 SUPERFAMILY SSF53218 186 328 1.31E-37 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 Gene3D G3DSA:2.40.340.10 339 413 1.9E-18 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 Pfam PF00994 Probable molybdopterin binding domain 189 326 6.8E-24 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 SMART SM00852 189 327 4.4E-36 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 Gene3D G3DSA:3.40.980.10 159 333 4.2E-49 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 Pfam PF03454 MoeA C-terminal region (domain IV) 341 410 5.8E-18 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 176 2.5E-40 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 SUPERFAMILY SSF63867 339 413 3.66E-18 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 SUPERFAMILY SSF63882 8 185 8.5E-52 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 323 1.4E-31 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS07060 706981ec42689c0338337bb330dcc82f 430 Gene3D G3DSA:2.170.190.11 50 150 7.0E-25 T 29-03-2018 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 SMART SM01016 5 95 7.6E-36 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 Pfam PF05746 DALR anticodon binding domain 438 556 7.9E-39 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 556 1.7E-189 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 Gene3D G3DSA:3.40.50.620 109 366 4.7E-59 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 Gene3D G3DSA:1.10.730.10 403 556 7.2E-49 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 SUPERFAMILY SSF52374 118 448 2.0E-98 T 29-03-2018 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 7.4E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 7.4E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 7.4E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 7.4E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 Pfam PF00750 tRNA synthetases class I (R) 104 400 1.5E-26 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 SUPERFAMILY SSF47323 432 556 1.77E-37 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 SUPERFAMILY SSF55190 5 115 1.22E-28 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 94 1.4E-25 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 556 28.866 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 Gene3D G3DSA:3.30.1360.70 3 108 2.1E-34 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CXR48_RS17655 e705bb54cc4e63c16d0b0f1eadeecc69 556 SMART SM00836 437 556 4.2E-57 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CXR48_RS02335 663243e44aa499c72616a819fa432287 349 Pfam PF01594 AI-2E family transporter 18 334 3.7E-57 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 SUPERFAMILY SSF101801 251 323 8.76E-17 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 PIRSF PIRSF002888 2 332 6.6E-122 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 322 4.2E-21 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 SUPERFAMILY SSF103039 47 232 4.19E-34 T 29-03-2018 IPR028976 CheC-like domain CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 1.9E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 212 230 1.9E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 116 135 1.9E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 91 107 1.9E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 4 322 8.9E-113 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 Gene3D G3DSA:3.40.1550.10 48 236 7.3E-50 T 29-03-2018 IPR028976 CheC-like domain CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 Pfam PF02154 Flagellar motor switch protein FliM 40 230 5.2E-82 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CXR48_RS08135 4d932402d7c03055e9fb426ec37ae603 332 Gene3D G3DSA:2.30.330.10 237 330 7.6E-20 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CXR48_RS14925 f98e9640b485128cd78003923581291f 496 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 341 348 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 PRINTS PR00481 Cytosol aminopeptidase signature 337 357 1.0E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 PRINTS PR00481 Cytosol aminopeptidase signature 365 380 1.0E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 PRINTS PR00481 Cytosol aminopeptidase signature 278 299 1.0E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 PRINTS PR00481 Cytosol aminopeptidase signature 256 273 1.0E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 PRINTS PR00481 Cytosol aminopeptidase signature 315 336 1.0E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 180 485 1.6E-116 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 Gene3D G3DSA:3.40.630.10 173 492 1.8E-128 T 29-03-2018 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 SUPERFAMILY SSF53187 176 488 1.26E-111 T 29-03-2018 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 SUPERFAMILY SSF52949 12 177 8.24E-35 T 29-03-2018 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 1 494 35.589 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 15 142 5.0E-24 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CXR48_RS14925 f98e9640b485128cd78003923581291f 496 Gene3D G3DSA:3.40.220.10 11 172 1.1E-26 T 29-03-2018 CXR48_RS03075 8fba856727be82f2a60f6e7728ac8889 244 Pfam PF02517 CAAX protease self-immunity 129 214 2.5E-16 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CXR48_RS06210 a33a079f9caec12fbeafd5e4ebe703b9 266 Gene3D G3DSA:3.40.50.300 59 249 3.8E-10 T 29-03-2018 CXR48_RS06210 a33a079f9caec12fbeafd5e4ebe703b9 266 SUPERFAMILY SSF52540 93 253 5.93E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS06210 a33a079f9caec12fbeafd5e4ebe703b9 266 Pfam PF01695 IstB-like ATP binding protein 116 227 9.8E-9 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CXR48_RS06210 a33a079f9caec12fbeafd5e4ebe703b9 266 SMART SM00382 116 256 1.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS17375 95f8c77c983f092950c969fad730ff97 436 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 2.3E-181 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS17375 95f8c77c983f092950c969fad730ff97 436 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.573 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS17375 95f8c77c983f092950c969fad730ff97 436 Gene3D G3DSA:3.65.10.10 21 221 7.7E-51 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CXR48_RS17375 95f8c77c983f092950c969fad730ff97 436 SUPERFAMILY SSF55205 2 417 4.19E-141 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CXR48_RS17375 95f8c77c983f092950c969fad730ff97 436 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 1.5E-122 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CXR48_RS17375 95f8c77c983f092950c969fad730ff97 436 Gene3D G3DSA:3.65.10.10 222 419 4.2E-50 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 Gene3D G3DSA:1.20.150.20 373 498 1.4E-50 T 29-03-2018 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 PIRSF PIRSF039088 1 501 8.6E-252 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 92 1.3E-20 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 SUPERFAMILY SSF47917 372 499 2.62E-48 T 29-03-2018 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 SUPERFAMILY SSF50615 10 94 1.31E-31 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 1.1E-264 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.6E-73 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 491 1.9E-47 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 51.607 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 Gene3D G3DSA:2.40.30.20 3 82 2.2E-39 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 Gene3D G3DSA:3.40.50.300 83 364 8.6E-119 T 29-03-2018 CXR48_RS17410 fd34697eee8ca3ecb1d7d342103afe1d 502 SUPERFAMILY SSF52540 95 370 3.29E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS02150 13630645b55f5c94dc01aa91328106a7 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS02150 13630645b55f5c94dc01aa91328106a7 504 SUPERFAMILY SSF56801 13 501 4.71E-134 T 29-03-2018 CXR48_RS02150 13630645b55f5c94dc01aa91328106a7 504 Gene3D G3DSA:3.40.50.980 1 169 8.7E-37 T 29-03-2018 CXR48_RS02150 13630645b55f5c94dc01aa91328106a7 504 Gene3D G3DSA:3.40.50.980 170 318 1.3E-35 T 29-03-2018 CXR48_RS02150 13630645b55f5c94dc01aa91328106a7 504 Pfam PF00501 AMP-binding enzyme 17 408 1.0E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS02150 13630645b55f5c94dc01aa91328106a7 504 Gene3D G3DSA:2.30.38.10 319 401 9.5E-26 T 29-03-2018 CXR48_RS02150 13630645b55f5c94dc01aa91328106a7 504 Gene3D G3DSA:3.30.300.30 403 504 4.1E-25 T 29-03-2018 CXR48_RS02150 13630645b55f5c94dc01aa91328106a7 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 491 4.1E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS07090 f162bf51d9640db1d477586797dc915f 230 Pfam PF00005 ABC transporter 21 169 9.4E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS07090 f162bf51d9640db1d477586797dc915f 230 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS07090 f162bf51d9640db1d477586797dc915f 230 Gene3D G3DSA:3.40.50.300 1 226 1.1E-64 T 29-03-2018 CXR48_RS07090 f162bf51d9640db1d477586797dc915f 230 SMART SM00382 30 217 4.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS07090 f162bf51d9640db1d477586797dc915f 230 SUPERFAMILY SSF52540 1 224 4.91E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04010 77bdab299cdc479e7207c22302f7e190 577 Gene3D G3DSA:3.40.50.300 318 570 1.9E-73 T 29-03-2018 CXR48_RS04010 77bdab299cdc479e7207c22302f7e190 577 SMART SM00382 356 540 1.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04010 77bdab299cdc479e7207c22302f7e190 577 Gene3D G3DSA:1.20.1560.10 1 314 2.4E-66 T 29-03-2018 CXR48_RS04010 77bdab299cdc479e7207c22302f7e190 577 Pfam PF00005 ABC transporter 347 496 1.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS04010 77bdab299cdc479e7207c22302f7e190 577 Pfam PF00664 ABC transporter transmembrane region 17 285 1.3E-41 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04010 77bdab299cdc479e7207c22302f7e190 577 SUPERFAMILY SSF52540 324 565 1.7E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04010 77bdab299cdc479e7207c22302f7e190 577 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS04010 77bdab299cdc479e7207c22302f7e190 577 SUPERFAMILY SSF90123 5 316 2.75E-71 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS02555 d418d465be8896dd9c280571970481a1 138 Pfam PF02566 OsmC-like protein 40 133 3.0E-17 T 29-03-2018 IPR003718 OsmC/Ohr family CXR48_RS02555 d418d465be8896dd9c280571970481a1 138 Gene3D G3DSA:2.20.25.10 1 37 6.5E-12 T 29-03-2018 CXR48_RS02555 d418d465be8896dd9c280571970481a1 138 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 133 1.8E-49 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CXR48_RS02555 d418d465be8896dd9c280571970481a1 138 SUPERFAMILY SSF82784 4 133 8.77E-36 T 29-03-2018 IPR003718 OsmC/Ohr family CXR48_RS02555 d418d465be8896dd9c280571970481a1 138 Gene3D G3DSA:3.30.300.20 43 138 8.7E-24 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS09470 e72162a873449f7f75d614c50fde72f2 325 SUPERFAMILY SSF52317 2 164 4.58E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS09470 e72162a873449f7f75d614c50fde72f2 325 Gene3D G3DSA:3.50.30.60 159 325 9.1E-42 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CXR48_RS09470 e72162a873449f7f75d614c50fde72f2 325 Gene3D G3DSA:3.40.50.10740 1 158 1.8E-47 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CXR48_RS09470 e72162a873449f7f75d614c50fde72f2 325 Pfam PF02016 LD-carboxypeptidase 12 311 4.1E-73 T 29-03-2018 IPR003507 Peptidase family S66 CXR48_RS09470 e72162a873449f7f75d614c50fde72f2 325 PIRSF PIRSF028757 1 325 4.0E-88 T 29-03-2018 IPR003507 Peptidase family S66 CXR48_RS09470 e72162a873449f7f75d614c50fde72f2 325 SUPERFAMILY SSF141986 165 315 1.2E-36 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 SMART SM00388 248 314 1.8E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 Gene3D G3DSA:3.30.565.10 309 471 2.3E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 313 8.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 470 1.9E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 SMART SM00304 188 240 7.6E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 SUPERFAMILY SSF55874 305 469 1.7E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 Gene3D G3DSA:3.30.450.20 30 162 1.8E-4 T 29-03-2018 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 Pfam PF00672 HAMP domain 191 236 3.9E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 SUPERFAMILY SSF158472 191 237 1.44E-9 T 29-03-2018 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 Gene3D G3DSA:1.10.287.130 234 308 9.8E-17 T 29-03-2018 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 SUPERFAMILY SSF47384 231 315 9.81E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 3.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 3.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 3.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 3.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS01940 d5c7f790d7e17a106bc63efea94e20d8 476 SMART SM00387 359 471 2.5E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 Gene3D G3DSA:3.40.50.300 1 188 1.6E-24 T 29-03-2018 CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 SUPERFAMILY SSF52540 867 1119 1.22E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 Gene3D G3DSA:1.20.1170.10 421 696 6.2E-6 T 29-03-2018 CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 SUPERFAMILY SSF52540 212 327 1.38E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 SUPERFAMILY SSF52540 1 178 1.38E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 Gene3D G3DSA:1.20.120.330 697 824 0.022 T 29-03-2018 CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1017 1085 1.7E-13 T 29-03-2018 CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 Gene3D G3DSA:3.40.50.300 836 1130 1.8E-17 T 29-03-2018 CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 Gene3D G3DSA:1.20.5.340 209 288 6.0E-4 T 29-03-2018 CXR48_RS05290 bf77befd0c0c62a1e537a27e0eb5238f 1130 Pfam PF13476 AAA domain 6 267 1.3E-22 T 29-03-2018 CXR48_RS01025 117f6dbb2945228b057875804c35a452 414 Pfam PF07075 Protein of unknown function (DUF1343) 57 414 2.5E-147 T 29-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CXR48_RS01025 117f6dbb2945228b057875804c35a452 414 PIRSF PIRSF016719 1 414 2.7E-173 T 29-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 Gene3D G3DSA:1.10.287.990 45 101 5.3E-21 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 Gene3D G3DSA:3.40.50.720 1 44 1.1E-4 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 447 7.4E-32 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 320 2.4E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 7.1E-39 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 7.1E-39 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 7.1E-39 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 7.1E-39 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 7.1E-39 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 SUPERFAMILY SSF51905 3 365 5.01E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 Gene3D G3DSA:3.50.50.60 110 248 5.1E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 SUPERFAMILY SSF55424 335 457 8.93E-34 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 Gene3D G3DSA:3.50.50.60 272 350 2.4E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 6.2E-62 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 6.2E-62 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 6.2E-62 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 6.2E-62 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 6.2E-62 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 6.2E-62 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 6.2E-62 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 6.2E-62 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 6.2E-62 T 29-03-2018 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 457 1.0E-161 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 Gene3D G3DSA:3.30.390.30 351 459 6.3E-35 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CXR48_RS03980 fc684b01ba2476f533c5630b729ada96 459 PIRSF PIRSF000350 1 452 1.0E-88 T 29-03-2018 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 Pfam PF13091 PLD-like domain 342 465 3.0E-30 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 Pfam PF13091 PLD-like domain 155 297 1.4E-13 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 Gene3D G3DSA:3.30.870.10 323 495 6.9E-35 T 29-03-2018 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 Pfam PF13396 Phospholipase_D-nuclease N-terminal 42 82 5.7E-7 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 Hamap MF_01916 Cardiolipin synthase. 35 500 37.271 T 29-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 SMART SM00155 413 440 2.6E-6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 SMART SM00155 237 264 4.8E-6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 SUPERFAMILY SSF56024 122 331 2.24E-50 T 29-03-2018 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 Gene3D G3DSA:3.30.870.10 108 303 5.8E-31 T 29-03-2018 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 38 500 9.7E-136 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CXR48_RS17605 0a280137656c7d39f14f8baa786067fe 500 SUPERFAMILY SSF56024 319 486 6.95E-45 T 29-03-2018 CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SUPERFAMILY SSF52540 14 368 8.89E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SUPERFAMILY SSF52540 802 1009 5.21E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 Pfam PF00270 DEAD/DEAH box helicase 625 784 2.7E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 Pfam PF00271 Helicase conserved C-terminal domain 828 929 3.9E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 Gene3D G3DSA:3.40.50.300 812 976 3.2E-26 T 29-03-2018 CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1097 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 37 1119 30.014 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 Gene3D G3DSA:3.40.50.300 605 807 3.7E-32 T 29-03-2018 CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SUPERFAMILY SSF52540 543 803 3.64E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 Pfam PF02559 CarD-like/TRCF domain 500 595 1.4E-31 T 29-03-2018 IPR003711 CarD-like/TRCF domain CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 Pfam PF03461 TRCF domain 1026 1117 1.9E-25 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SUPERFAMILY SSF141259 491 568 2.22E-26 T 29-03-2018 IPR003711 CarD-like/TRCF domain CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 Gene3D G3DSA:3.40.50.300 14 373 6.4E-5 T 29-03-2018 CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SUPERFAMILY SSF52540 377 490 7.17E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SMART SM00982 1024 1124 1.6E-34 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SMART SM00487 620 810 6.6E-36 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SMART SM00490 846 930 5.3E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SMART SM01058 499 596 2.7E-50 T 29-03-2018 IPR003711 CarD-like/TRCF domain CXR48_RS00340 5b81704f89182c9f319bba1024e92dc9 1177 SUPERFAMILY SSF143517 1011 1169 4.05E-36 T 29-03-2018 CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 Gene3D G3DSA:3.40.50.720 1 44 1.0E-9 T 29-03-2018 CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 Gene3D G3DSA:3.40.50.720 45 252 4.0E-53 T 29-03-2018 CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 5.7E-56 T 29-03-2018 CXR48_RS06955 f45f688c1d5ff25632967f5fdfc08d8b 254 SUPERFAMILY SSF51735 3 249 5.68E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 326 5.8E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 275 289 5.8E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 303 5.8E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 5.8E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 SUPERFAMILY SSF55874 184 347 1.28E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 347 5.7E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 Gene3D G3DSA:3.30.565.10 198 356 6.8E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 Gene3D G3DSA:1.10.287.130 133 189 1.4E-17 T 29-03-2018 CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 SUPERFAMILY SSF47384 111 193 1.28E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 Pfam PF00512 His Kinase A (phospho-acceptor) domain 129 192 1.4E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 SMART SM00387 238 348 1.9E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 SMART SM00388 128 194 9.5E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS16405 81b14c62edc45b56dbb2cd8cbd575e8e 369 Gene3D G3DSA:3.30.450.20 95 132 7.6E-5 T 29-03-2018 CXR48_RS09085 ad89527d67431b2e4f8d9d7e7781730d 423 SUPERFAMILY SSF51011 327 422 2.75E-27 T 29-03-2018 CXR48_RS09085 ad89527d67431b2e4f8d9d7e7781730d 423 Gene3D G3DSA:2.60.40.1180 323 423 4.0E-31 T 29-03-2018 CXR48_RS09085 ad89527d67431b2e4f8d9d7e7781730d 423 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 107 175 9.1E-5 T 29-03-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 CXR48_RS09085 ad89527d67431b2e4f8d9d7e7781730d 423 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 334 419 1.5E-5 T 29-03-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 CXR48_RS09085 ad89527d67431b2e4f8d9d7e7781730d 423 Gene3D G3DSA:3.20.20.80 49 322 3.3E-62 T 29-03-2018 CXR48_RS09085 ad89527d67431b2e4f8d9d7e7781730d 423 SUPERFAMILY SSF51445 48 331 6.7E-49 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS17720 d823d7616c0b5bf0471ed85c3ab8e28c 690 Pfam PF00912 Transglycosylase 65 237 7.3E-62 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CXR48_RS17720 d823d7616c0b5bf0471ed85c3ab8e28c 690 Pfam PF00905 Penicillin binding protein transpeptidase domain 330 599 1.2E-26 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS17720 d823d7616c0b5bf0471ed85c3ab8e28c 690 Gene3D G3DSA:3.40.710.10 257 656 2.6E-102 T 29-03-2018 CXR48_RS17720 d823d7616c0b5bf0471ed85c3ab8e28c 690 Gene3D G3DSA:1.10.3810.10 55 256 7.8E-74 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CXR48_RS17720 d823d7616c0b5bf0471ed85c3ab8e28c 690 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 609 2.8E-167 T 29-03-2018 CXR48_RS17720 d823d7616c0b5bf0471ed85c3ab8e28c 690 SUPERFAMILY SSF53955 50 262 2.11E-72 T 29-03-2018 IPR023346 Lysozyme-like domain CXR48_RS17720 d823d7616c0b5bf0471ed85c3ab8e28c 690 SUPERFAMILY SSF56601 271 660 4.58E-108 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS17720 d823d7616c0b5bf0471ed85c3ab8e28c 690 SUPERFAMILY SSF56601 219 241 4.58E-108 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS00670 3e74d236eb0d2d081920339e3ad6aaf1 232 Gene3D G3DSA:3.40.50.790 68 144 1.2E-36 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CXR48_RS00670 3e74d236eb0d2d081920339e3ad6aaf1 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00670 3e74d236eb0d2d081920339e3ad6aaf1 232 SUPERFAMILY SSF56808 6 226 3.4E-85 T 29-03-2018 IPR023674 Ribosomal protein L1-like CXR48_RS00670 3e74d236eb0d2d081920339e3ad6aaf1 232 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 7.2E-56 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CXR48_RS00670 3e74d236eb0d2d081920339e3ad6aaf1 232 PIRSF PIRSF002155 1 227 1.0E-81 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00670 3e74d236eb0d2d081920339e3ad6aaf1 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 44.655 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CXR48_RS00670 3e74d236eb0d2d081920339e3ad6aaf1 232 Gene3D G3DSA:3.30.190.20 145 224 2.5E-20 T 29-03-2018 CXR48_RS00670 3e74d236eb0d2d081920339e3ad6aaf1 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 2.9E-108 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 Pfam PF00672 HAMP domain 303 351 5.3E-16 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 Gene3D G3DSA:1.10.287.950 301 411 5.2E-9 T 29-03-2018 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 SMART SM00304 303 355 4.2E-18 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 Gene3D G3DSA:3.30.450.20 172 279 1.5E-14 T 29-03-2018 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 Gene3D G3DSA:3.30.450.20 36 171 9.0E-20 T 29-03-2018 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 Pfam PF02743 Cache domain 42 263 1.5E-26 T 29-03-2018 IPR033479 Double Cache domain 1 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 SUPERFAMILY SSF58104 390 659 9.02E-73 T 29-03-2018 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 SUPERFAMILY SSF58104 323 357 9.02E-73 T 29-03-2018 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 431 612 2.6E-55 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 SMART SM00319 33 151 1.4E-8 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 SMART SM00283 384 659 1.8E-99 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 SUPERFAMILY SSF103190 90 192 1.02E-10 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS14500 1a2521f3c9c488a0923f595002026963 662 Gene3D G3DSA:1.10.287.950 412 662 8.9E-57 T 29-03-2018 CXR48_RS12675 99ff7a8d8b79b64c0eb464f5b2b1b63a 379 Gene3D G3DSA:3.90.1150.10 242 379 1.9E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS12675 99ff7a8d8b79b64c0eb464f5b2b1b63a 379 Pfam PF00266 Aminotransferase class-V 4 365 1.4E-82 T 29-03-2018 IPR000192 Aminotransferase class V domain CXR48_RS12675 99ff7a8d8b79b64c0eb464f5b2b1b63a 379 SUPERFAMILY SSF53383 3 377 1.1E-99 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS12675 99ff7a8d8b79b64c0eb464f5b2b1b63a 379 Gene3D G3DSA:3.40.640.10 12 241 5.1E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS12675 99ff7a8d8b79b64c0eb464f5b2b1b63a 379 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CXR48_RS12675 99ff7a8d8b79b64c0eb464f5b2b1b63a 379 PIRSF PIRSF005572 1 379 7.1E-126 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CXR48_RS14060 fba58109ff04c275232df4cfa1af69ef 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 241 255 1.1E-39 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14060 fba58109ff04c275232df4cfa1af69ef 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 261 280 1.1E-39 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14060 fba58109ff04c275232df4cfa1af69ef 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 151 165 1.1E-39 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14060 fba58109ff04c275232df4cfa1af69ef 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 91 105 1.1E-39 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14060 fba58109ff04c275232df4cfa1af69ef 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 168 180 1.1E-39 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14060 fba58109ff04c275232df4cfa1af69ef 328 Pfam PF12679 ABC-2 family transporter protein 70 257 1.3E-8 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CXR48_RS07815 c35793adb9f834f725889991dbee5d49 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 7.3E-74 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CXR48_RS07815 c35793adb9f834f725889991dbee5d49 204 Pfam PF00625 Guanylate kinase 7 183 9.3E-55 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CXR48_RS07815 c35793adb9f834f725889991dbee5d49 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CXR48_RS07815 c35793adb9f834f725889991dbee5d49 204 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 37.148 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CXR48_RS07815 c35793adb9f834f725889991dbee5d49 204 SMART SM00072 4 187 2.9E-82 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CXR48_RS07815 c35793adb9f834f725889991dbee5d49 204 SUPERFAMILY SSF52540 3 192 3.49E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07815 c35793adb9f834f725889991dbee5d49 204 Gene3D G3DSA:3.40.50.300 84 187 7.2E-31 T 29-03-2018 CXR48_RS07815 c35793adb9f834f725889991dbee5d49 204 Gene3D G3DSA:3.40.50.300 1 51 1.1E-9 T 29-03-2018 CXR48_RS07815 c35793adb9f834f725889991dbee5d49 204 Gene3D G3DSA:3.30.63.10 52 83 1.9E-26 T 29-03-2018 CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 Gene3D G3DSA:3.40.50.720 2 44 2.2E-10 T 29-03-2018 CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 Gene3D G3DSA:3.40.50.720 45 261 7.0E-62 T 29-03-2018 CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 SUPERFAMILY SSF51735 8 260 3.08E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 0.0015 T 29-03-2018 CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.0E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.0E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.0E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.0E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.0E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.0E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 7 261 1.0E-113 T 29-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CXR48_RS09120 cdbc67f203d0a163d954378077a1a446 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 259 6.3E-67 T 29-03-2018 CXR48_RS07085 d75e8dc973a77677116f56121f01897f 378 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 377 6.3E-29 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CXR48_RS07085 d75e8dc973a77677116f56121f01897f 378 Gene3D G3DSA:1.20.1600.10 82 312 2.6E-10 T 29-03-2018 CXR48_RS07085 d75e8dc973a77677116f56121f01897f 378 Gene3D G3DSA:2.40.50.100 32 81 0.59 T 29-03-2018 CXR48_RS07085 d75e8dc973a77677116f56121f01897f 378 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 47 265 1.4E-14 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CXR48_RS01800 5ac0cd8f709fd92aeb919ec82dcf5970 243 Pfam PF00975 Thioesterase domain 15 236 4.7E-57 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CXR48_RS01800 5ac0cd8f709fd92aeb919ec82dcf5970 243 SUPERFAMILY SSF53474 11 234 3.38E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS01800 5ac0cd8f709fd92aeb919ec82dcf5970 243 Gene3D G3DSA:3.40.50.1820 9 237 4.3E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 SUPERFAMILY SSF53850 90 295 3.26E-42 T 29-03-2018 CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 Gene3D G3DSA:3.40.190.10 88 176 1.5E-19 T 29-03-2018 CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 Gene3D G3DSA:1.10.10.10 1 83 7.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.4E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 SUPERFAMILY SSF46785 1 110 9.47E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 Pfam PF03466 LysR substrate binding domain 90 289 1.7E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS19235 90a537207a04af126ddb4746f62b9c44 298 Gene3D G3DSA:3.40.190.10 177 265 5.6E-21 T 29-03-2018 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 SUPERFAMILY SSF54211 4 159 2.66E-31 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 Pfam PF08544 GHMP kinases C terminal 205 282 2.5E-11 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 PIRSF PIRSF000676 4 301 1.1E-92 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 Pfam PF00288 GHMP kinases N terminal domain 83 144 2.4E-13 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 90 101 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 TIGRFAM TIGR00191 thrB: homoserine kinase 8 305 3.0E-100 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 Gene3D G3DSA:3.30.230.10 6 165 9.4E-32 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 Hamap MF_00384 Homoserine kinase [thrB]. 8 298 32.061 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 SUPERFAMILY SSF55060 164 285 5.76E-34 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 Gene3D G3DSA:3.30.70.890 166 294 6.1E-25 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 PRINTS PR00958 Homoserine kinase signature 15 30 2.2E-39 T 29-03-2018 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 PRINTS PR00958 Homoserine kinase signature 97 112 2.2E-39 T 29-03-2018 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 PRINTS PR00958 Homoserine kinase signature 131 144 2.2E-39 T 29-03-2018 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 PRINTS PR00958 Homoserine kinase signature 169 186 2.2E-39 T 29-03-2018 CXR48_RS15060 edae3a232516fc52c0612000e5cb8be3 309 PRINTS PR00958 Homoserine kinase signature 249 264 2.2E-39 T 29-03-2018 CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 Gene3D G3DSA:1.10.357.10 75 204 1.5E-11 T 29-03-2018 CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 SUPERFAMILY SSF46689 10 89 2.0E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 Pfam PF08360 QacR-like protein, C-terminal region 73 196 7.7E-23 T 29-03-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 Gene3D G3DSA:1.10.10.60 2 50 4.6E-16 T 29-03-2018 CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.6E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 SUPERFAMILY SSF48498 85 196 2.11E-40 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 Gene3D G3DSA:1.10.10.60 51 74 5.3E-13 T 29-03-2018 CXR48_RS05260 2a6437c0b6beb5146dda5c5197958c7e 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CXR48_RS18085 13cc9f8c48af347b095ca3fb340716ee 321 Gene3D G3DSA:1.10.287.90 30 117 3.3E-26 T 29-03-2018 CXR48_RS18085 13cc9f8c48af347b095ca3fb340716ee 321 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 151 228 5.6E-5 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18085 13cc9f8c48af347b095ca3fb340716ee 321 SUPERFAMILY SSF81464 20 120 1.8E-23 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18085 13cc9f8c48af347b095ca3fb340716ee 321 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 40 112 1.9E-10 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18085 13cc9f8c48af347b095ca3fb340716ee 321 SUPERFAMILY SSF49503 127 279 2.74E-41 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS18085 13cc9f8c48af347b095ca3fb340716ee 321 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 14 242 1.0E-132 T 29-03-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 CXR48_RS18085 13cc9f8c48af347b095ca3fb340716ee 321 Gene3D G3DSA:2.60.40.420 118 314 1.2E-38 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS18085 13cc9f8c48af347b095ca3fb340716ee 321 PIRSF PIRSF000292 4 312 3.9E-111 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CXR48_RS01165 18536aa6a88bb2a81d52b3f7487030dd 310 Pfam PF00005 ABC transporter 17 160 9.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS01165 18536aa6a88bb2a81d52b3f7487030dd 310 SMART SM00382 26 209 4.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS01165 18536aa6a88bb2a81d52b3f7487030dd 310 Gene3D G3DSA:3.40.50.300 1 270 6.4E-68 T 29-03-2018 CXR48_RS01165 18536aa6a88bb2a81d52b3f7487030dd 310 SUPERFAMILY SSF52540 2 224 9.57E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01165 18536aa6a88bb2a81d52b3f7487030dd 310 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS07745 bb2bd60a054433377d3d080bf8c636f3 239 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 235 38.079 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07745 bb2bd60a054433377d3d080bf8c636f3 239 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 57 70 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07745 bb2bd60a054433377d3d080bf8c636f3 239 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 231 4.1E-60 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07745 bb2bd60a054433377d3d080bf8c636f3 239 Gene3D G3DSA:3.20.20.70 1 234 8.5E-60 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS07745 bb2bd60a054433377d3d080bf8c636f3 239 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 230 2.1E-44 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07745 bb2bd60a054433377d3d080bf8c636f3 239 SUPERFAMILY SSF51366 1 235 1.66E-68 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CXR48_RS07745 bb2bd60a054433377d3d080bf8c636f3 239 SMART SM00934 5 230 8.5E-85 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS13920 bd78486e9cc583261e0b6b45fdc5ffd1 234 SMART SM00382 30 201 6.6E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS13920 bd78486e9cc583261e0b6b45fdc5ffd1 234 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS13920 bd78486e9cc583261e0b6b45fdc5ffd1 234 Pfam PF00005 ABC transporter 22 153 2.9E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS13920 bd78486e9cc583261e0b6b45fdc5ffd1 234 Gene3D G3DSA:3.40.50.300 4 227 1.4E-50 T 29-03-2018 CXR48_RS13920 bd78486e9cc583261e0b6b45fdc5ffd1 234 SUPERFAMILY SSF52540 14 216 1.54E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12285 d83137932521fb2c43fe342872eef21d 44 Pfam PF14141 YqzM-like protein 2 43 1.3E-23 T 29-03-2018 IPR025416 YqzM-like protein CXR48_RS09930 575d97a243660963a7d7929a81e81224 155 Pfam PF16219 Domain of unknown function (DUF4879) 30 145 2.6E-19 T 29-03-2018 IPR032624 Protein of unknown function DUF4879 CXR48_RS08490 14dbfed806ff8664ff3c6b6aeacea2ff 143 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 3.4E-21 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CXR48_RS08490 14dbfed806ff8664ff3c6b6aeacea2ff 143 Gene3D G3DSA:1.20.1500.10 8 116 2.0E-28 T 29-03-2018 IPR023378 YheA/YmcA-like domain CXR48_RS08490 14dbfed806ff8664ff3c6b6aeacea2ff 143 SUPERFAMILY SSF158622 4 123 1.31E-33 T 29-03-2018 IPR023378 YheA/YmcA-like domain CXR48_RS08490 14dbfed806ff8664ff3c6b6aeacea2ff 143 PIRSF PIRSF021287 1 123 2.9E-52 T 29-03-2018 IPR016783 Biofilm formation YmcA CXR48_RS03185 0dd4829cffbc5d9856709c3cf3e78f82 348 Gene3D G3DSA:2.130.10.10 196 347 6.5E-13 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CXR48_RS03185 0dd4829cffbc5d9856709c3cf3e78f82 348 Gene3D G3DSA:2.140.10.30 24 193 2.1E-8 T 29-03-2018 CXR48_RS03185 0dd4829cffbc5d9856709c3cf3e78f82 348 Pfam PF07676 WD40-like Beta Propeller Repeat 220 248 1.9E-4 T 29-03-2018 IPR011659 WD40-like Beta Propeller CXR48_RS03185 0dd4829cffbc5d9856709c3cf3e78f82 348 SUPERFAMILY SSF69304 42 343 5.62E-19 T 29-03-2018 CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 Pfam PF01424 R3H domain 145 203 1.8E-16 T 29-03-2018 IPR001374 R3H domain GO:0003676 CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 Gene3D G3DSA:3.30.1370.50 141 212 2.7E-21 T 29-03-2018 IPR001374 R3H domain GO:0003676 CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 SUPERFAMILY SSF82708 148 205 3.14E-10 T 29-03-2018 IPR001374 R3H domain GO:0003676 CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 Pfam PF13083 KH domain 68 129 4.1E-12 T 29-03-2018 CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 Gene3D G3DSA:3.30.300.20 58 140 1.4E-18 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 Gene3D G3DSA:3.30.30.80 3 54 7.6E-19 T 29-03-2018 CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 Pfam PF14804 Jag N-terminus 8 54 2.9E-18 T 29-03-2018 IPR032782 Jag, N-terminal CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 SMART SM00393 126 205 1.5E-25 T 29-03-2018 IPR001374 R3H domain GO:0003676 CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 SUPERFAMILY SSF54814 69 119 5.49E-5 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CXR48_RS19420 3f2f4178bf58995e01be22d2d1c953e8 213 SMART SM01245 5 57 6.8E-21 T 29-03-2018 IPR032782 Jag, N-terminal CXR48_RS10485 06b0e9afec48af918ae4809ddff5af2e 50 Pfam PF14139 YpzG-like protein 1 49 4.8E-26 T 29-03-2018 IPR025413 YpzG-like protein CXR48_RS17895 884e55fbae13855de14625739aae8713 282 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 276 5.3E-100 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CXR48_RS17895 884e55fbae13855de14625739aae8713 282 SUPERFAMILY SSF51735 3 277 6.36E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS17895 884e55fbae13855de14625739aae8713 282 Pfam PF04321 RmlD substrate binding domain 3 277 4.8E-101 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CXR48_RS17895 884e55fbae13855de14625739aae8713 282 Gene3D G3DSA:3.90.25.10 198 265 3.4E-23 T 29-03-2018 CXR48_RS17895 884e55fbae13855de14625739aae8713 282 Gene3D G3DSA:3.40.50.720 2 197 1.2E-36 T 29-03-2018 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 Gene3D G3DSA:3.40.50.720 149 326 6.1E-19 T 29-03-2018 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 SUPERFAMILY SSF51905 8 314 3.18E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.4E-16 T 29-03-2018 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 3.4E-16 T 29-03-2018 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 3.4E-16 T 29-03-2018 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 Gene3D G3DSA:3.50.50.60 1 139 9.6E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 Hamap MF_01685 Ferredoxin--NADP reductase. 7 328 44.598 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 293 3.4E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 8.4E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 8.4E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 8.4E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 8.4E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 8.4E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS14960 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 8.4E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 Gene3D G3DSA:1.10.8.10 126 223 9.9E-29 T 29-03-2018 CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 108 5.4E-7 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 SMART SM01086 359 453 4.7E-26 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 Pfam PF07724 AAA domain (Cdc48 subfamily) 212 353 8.0E-42 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 SMART SM00382 51 360 3.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 467 3.0E-226 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 Gene3D G3DSA:3.40.50.300 51 125 1.7E-5 T 29-03-2018 CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 359 429 4.1E-8 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 SUPERFAMILY SSF52540 6 465 4.03E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 Gene3D G3DSA:1.10.8.60 359 455 4.1E-32 T 29-03-2018 CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 Gene3D G3DSA:1.10.8.10 224 266 1.7E-16 T 29-03-2018 CXR48_RS08055 177f8f6e395c0be84ec5a4394b405fa3 467 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 467 44.232 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 184 1.0E-34 T 29-03-2018 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 SUPERFAMILY SSF51905 143 281 2.09E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 8.6E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 8.6E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 8.6E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 Gene3D G3DSA:3.50.50.60 145 174 1.2E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 SUPERFAMILY SSF51905 1 185 2.49E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 Gene3D G3DSA:3.50.50.60 175 343 2.2E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.0E-7 T 29-03-2018 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 5.0E-7 T 29-03-2018 CXR48_RS02680 067a30fc610ca6b1dc924a20cbedd6bf 345 Gene3D G3DSA:3.50.50.60 1 144 7.7E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS07180 d225f94499ec9e7cb99a7771ddb5efc7 555 Pfam PF00753 Metallo-beta-lactamase superfamily 20 167 1.1E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS07180 d225f94499ec9e7cb99a7771ddb5efc7 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 29-03-2018 IPR001587 Ribonuclease J, conserved site CXR48_RS07180 d225f94499ec9e7cb99a7771ddb5efc7 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 47.814 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CXR48_RS07180 d225f94499ec9e7cb99a7771ddb5efc7 555 SUPERFAMILY SSF56281 11 423 1.94E-95 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS07180 d225f94499ec9e7cb99a7771ddb5efc7 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 553 4.6E-236 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CXR48_RS07180 d225f94499ec9e7cb99a7771ddb5efc7 555 SMART SM00849 21 215 4.9E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS07180 d225f94499ec9e7cb99a7771ddb5efc7 555 Gene3D G3DSA:3.60.15.10 3 448 2.7E-62 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS07180 d225f94499ec9e7cb99a7771ddb5efc7 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 360 408 5.1E-8 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CXR48_RS07180 d225f94499ec9e7cb99a7771ddb5efc7 555 PIRSF PIRSF004803 1 555 6.7E-248 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CXR48_RS04745 c29f87b33f4b40272585b88e132a1065 444 Pfam PF00571 CBS domain 290 338 4.0E-5 T 29-03-2018 IPR000644 CBS domain CXR48_RS04745 c29f87b33f4b40272585b88e132a1065 444 Pfam PF00571 CBS domain 217 272 1.8E-4 T 29-03-2018 IPR000644 CBS domain CXR48_RS04745 c29f87b33f4b40272585b88e132a1065 444 Pfam PF01595 Domain of unknown function DUF21 7 201 7.3E-48 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CXR48_RS04745 c29f87b33f4b40272585b88e132a1065 444 Gene3D G3DSA:3.30.465.10 345 431 3.2E-18 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS04745 c29f87b33f4b40272585b88e132a1065 444 SUPERFAMILY SSF56176 352 430 7.09E-16 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS04745 c29f87b33f4b40272585b88e132a1065 444 Gene3D G3DSA:3.10.580.10 195 344 2.5E-30 T 29-03-2018 CXR48_RS04745 c29f87b33f4b40272585b88e132a1065 444 SUPERFAMILY SSF54631 204 341 6.95E-29 T 29-03-2018 CXR48_RS04745 c29f87b33f4b40272585b88e132a1065 444 Pfam PF03471 Transporter associated domain 355 430 4.7E-16 T 29-03-2018 IPR005170 Transporter-associated domain CXR48_RS04745 c29f87b33f4b40272585b88e132a1065 444 SMART SM01091 354 431 4.9E-20 T 29-03-2018 IPR005170 Transporter-associated domain CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 2.9E-109 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 29-03-2018 IPR033135 ClpP, histidine active site CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.338 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 Gene3D G3DSA:3.90.226.10 2 194 1.0E-46 T 29-03-2018 CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 Pfam PF00574 Clp protease 13 192 8.4E-87 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 SUPERFAMILY SSF52096 10 193 4.56E-73 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 29-03-2018 IPR018215 ClpP, Ser active site CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 7.1E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 7.1E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 7.1E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 7.1E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CXR48_RS16305 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 7.1E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Gene3D G3DSA:1.10.150.20 498 547 1.0E-21 T 29-03-2018 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 SUPERFAMILY SSF50249 313 396 5.14E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 662 7.3E-286 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 SMART SM00532 5 443 1.0E-297 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 SMART SM00278 475 494 140.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 SMART SM00278 441 460 200.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 SMART SM00278 539 558 1.6 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 593 663 7.9E-14 T 29-03-2018 IPR001357 BRCT domain CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 327 342 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 SUPERFAMILY SSF52113 589 666 1.89E-20 T 29-03-2018 IPR001357 BRCT domain CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Gene3D G3DSA:3.30.470.30 119 234 3.9E-51 T 29-03-2018 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Hamap MF_01588 DNA ligase [ligA]. 4 666 54.341 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 SUPERFAMILY SSF56091 2 312 2.4E-124 T 29-03-2018 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Gene3D G3DSA:3.30.1490.70 235 317 3.3E-30 T 29-03-2018 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Gene3D G3DSA:1.10.150.20 548 612 2.0E-8 T 29-03-2018 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 404 429 2.6E-9 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Gene3D G3DSA:3.40.50.10190 613 668 3.5E-17 T 29-03-2018 IPR001357 BRCT domain CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Gene3D G3DSA:1.10.287.610 1 69 4.0E-27 T 29-03-2018 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Gene3D G3DSA:2.40.50.140 318 386 1.0E-31 T 29-03-2018 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 PIRSF PIRSF001604 1 668 5.8E-264 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 SMART SM00292 592 668 3.1E-11 T 29-03-2018 IPR001357 BRCT domain CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 318 394 1.4E-33 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Pfam PF14520 Helix-hairpin-helix domain 443 497 5.5E-4 T 29-03-2018 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Pfam PF12826 Helix-hairpin-helix motif 505 567 5.5E-25 T 29-03-2018 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 SUPERFAMILY SSF47781 400 579 1.33E-64 T 29-03-2018 IPR010994 RuvA domain 2-like CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 314 3.8E-139 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CXR48_RS03365 ef3bc9db09430571dddbd719d329d2fc 668 Gene3D G3DSA:1.10.150.20 427 497 3.8E-29 T 29-03-2018 CXR48_RS10900 ce893770ef567554f3c34104cd5fa4ec 262 SUPERFAMILY SSF56300 43 258 1.05E-34 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS10900 ce893770ef567554f3c34104cd5fa4ec 262 Gene3D G3DSA:3.60.21.10 44 240 8.6E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS10900 ce893770ef567554f3c34104cd5fa4ec 262 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 49 204 5.9E-12 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 217 2.8E-45 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 Gene3D G3DSA:3.30.950.10 129 260 9.0E-37 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 Gene3D G3DSA:3.40.50.10090 261 443 6.3E-11 T 29-03-2018 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 SUPERFAMILY SSF53790 2 254 1.57E-78 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 SUPERFAMILY SSF69618 253 449 2.62E-9 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 Gene3D G3DSA:3.40.1010.10 3 128 4.3E-35 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 PIRSF PIRSF036426 1 254 3.2E-94 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CXR48_RS01720 9d03ca9aaf2eea087a2443333ce38920 479 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 241 1.1E-92 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 SUPERFAMILY SSF46689 57 115 3.72E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 SUPERFAMILY SSF46689 5 55 5.82E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 Pfam PF12833 Helix-turn-helix domain 28 104 2.0E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 Gene3D G3DSA:1.10.10.60 3 61 3.8E-11 T 29-03-2018 CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 Gene3D G3DSA:1.10.10.60 62 122 1.4E-8 T 29-03-2018 CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 Pfam PF06445 GyrI-like small molecule binding domain 128 287 5.4E-31 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 SMART SM00871 128 288 3.2E-35 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 SMART SM00342 21 104 2.0E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 Gene3D G3DSA:3.20.80.10 123 288 6.7E-41 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CXR48_RS12395 f0a063f3095a08ec20f7d5b9664e817b 293 SUPERFAMILY SSF55136 128 290 7.06E-29 T 29-03-2018 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.5E-45 T 29-03-2018 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 SUPERFAMILY SSF52540 31 222 1.08E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 238 362 4.1E-11 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 SUPERFAMILY SSF48019 244 363 1.45E-25 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 Gene3D G3DSA:1.20.272.10 243 364 1.5E-19 T 29-03-2018 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 Gene3D G3DSA:3.40.50.300 2 166 2.7E-41 T 29-03-2018 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 6.9E-145 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 3.5E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 3.5E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 Gene3D G3DSA:1.10.8.60 167 242 1.6E-20 T 29-03-2018 CXR48_RS00135 b6900d48636fea7c5a4cb51116648587 563 SMART SM00382 37 179 2.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS01050 3cb85f9677be1052787b5a4cf6a5cafe 158 Gene3D G3DSA:3.40.630.30 2 155 1.2E-12 T 29-03-2018 CXR48_RS01050 3cb85f9677be1052787b5a4cf6a5cafe 158 SUPERFAMILY SSF55729 1 151 2.02E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS01050 3cb85f9677be1052787b5a4cf6a5cafe 158 Pfam PF00583 Acetyltransferase (GNAT) family 41 137 9.2E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS01385 0ae5c85624fa6bfaee2beabdeb20f3bf 297 Gene3D G3DSA:1.20.1510.10 8 211 9.2E-43 T 29-03-2018 CXR48_RS01385 0ae5c85624fa6bfaee2beabdeb20f3bf 297 Gene3D G3DSA:3.30.70.1350 212 297 3.1E-21 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CXR48_RS01385 0ae5c85624fa6bfaee2beabdeb20f3bf 297 SUPERFAMILY SSF160240 215 294 2.22E-18 T 29-03-2018 CXR48_RS01385 0ae5c85624fa6bfaee2beabdeb20f3bf 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 217 294 1.0E-20 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CXR48_RS01385 0ae5c85624fa6bfaee2beabdeb20f3bf 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 10 294 2.9E-85 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CXR48_RS01385 0ae5c85624fa6bfaee2beabdeb20f3bf 297 SUPERFAMILY SSF161111 7 213 1.96E-49 T 29-03-2018 CXR48_RS01385 0ae5c85624fa6bfaee2beabdeb20f3bf 297 Pfam PF01545 Cation efflux family 14 212 3.1E-47 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CXR48_RS00775 cb5cc3a5fc0650741768f0402dc689c4 66 SUPERFAMILY SSF46561 1 63 4.84E-24 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00775 cb5cc3a5fc0650741768f0402dc689c4 66 Gene3D G3DSA:1.10.287.310 1 65 4.8E-27 T 29-03-2018 CXR48_RS00775 cb5cc3a5fc0650741768f0402dc689c4 66 Pfam PF00831 Ribosomal L29 protein 4 60 1.3E-26 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00775 cb5cc3a5fc0650741768f0402dc689c4 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00775 cb5cc3a5fc0650741768f0402dc689c4 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 19.203 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00775 cb5cc3a5fc0650741768f0402dc689c4 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 5.7E-25 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 498 8.8E-119 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 Gene3D G3DSA:1.20.1480.30 95 223 2.3E-4 T 29-03-2018 CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 Pfam PF00460 Flagella basal body rod protein 8 38 5.5E-12 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 SUPERFAMILY SSF64518 150 498 1.7E-23 T 29-03-2018 CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 PRINTS PR01005 Flagellar hook-associated protein signature 134 154 5.4E-9 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 PRINTS PR01005 Flagellar hook-associated protein signature 167 191 5.4E-9 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 PRINTS PR01005 Flagellar hook-associated protein signature 225 243 5.4E-9 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 5.4E-9 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CXR48_RS16675 2ebd952a91bc049b2f4916e344809a64 505 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 439 498 3.2E-13 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 SUPERFAMILY SSF54897 32 91 1.79E-8 T 29-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 SUPERFAMILY SSF52743 113 375 1.83E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 136 147 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 322 332 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 PRINTS PR00723 Subtilisin serine protease family (S8) signature 131 150 8.6E-16 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 179 8.6E-16 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 PRINTS PR00723 Subtilisin serine protease family (S8) signature 321 337 8.6E-16 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 Pfam PF05922 Peptidase inhibitor I9 24 91 1.3E-4 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 Gene3D G3DSA:3.30.70.80 30 78 3.3E-10 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 Gene3D G3DSA:3.40.50.200 79 378 3.7E-87 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 170 180 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CXR48_RS18195 60e4bf0f35eead94d6396f8e65c346ab 581 Pfam PF00082 Subtilase family 131 372 1.6E-53 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS12385 8736cccbc7a537150ea3ed10cad068f2 280 SUPERFAMILY SSF52266 2 272 1.08E-79 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS12385 8736cccbc7a537150ea3ed10cad068f2 280 Gene3D G3DSA:3.40.50.1110 1 245 5.3E-50 T 29-03-2018 CXR48_RS12385 8736cccbc7a537150ea3ed10cad068f2 280 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 5 225 9.7E-53 T 29-03-2018 IPR005181 Sialate O-acetylesterase domain CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 Pfam PF17392 Urocanase C-terminal domain 348 542 4.3E-95 T 29-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 Gene3D G3DSA:3.40.1770.10 192 550 1.7E-163 T 29-03-2018 CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 Gene3D G3DSA:3.40.1770.10 6 150 6.9E-26 T 29-03-2018 CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 Pfam PF17391 Urocanase N-terminal domain 8 134 2.3E-60 T 29-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 SUPERFAMILY SSF111326 6 551 7.98E-257 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 550 0.0 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 ProSitePatterns PS01233 Urocanase signature. 438 453 - T 29-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 Hamap MF_00577 Urocanate hydratase [hutU]. 2 552 51.756 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 PIRSF PIRSF001423 1 554 9.3E-296 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18585 e97fd31bb053ec59699b1839d2cd6bee 554 Pfam PF01175 Urocanase Rossmann-like domain 137 345 6.0E-89 T 29-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS13635 dbd77d3494963665ff7c4ff9a9833a6f 73 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 11 65 6.9E-22 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CXR48_RS13635 dbd77d3494963665ff7c4ff9a9833a6f 73 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 44 58 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CXR48_RS13635 dbd77d3494963665ff7c4ff9a9833a6f 73 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 26 35 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CXR48_RS04820 e7b32a78479014f0901e120a3adc68e1 166 SUPERFAMILY SSF52402 5 166 2.34E-30 T 29-03-2018 CXR48_RS04820 e7b32a78479014f0901e120a3adc68e1 166 Gene3D G3DSA:3.40.50.620 3 166 6.8E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS04820 e7b32a78479014f0901e120a3adc68e1 166 PRINTS PR01438 Universal stress protein signature 4 22 1.5E-14 T 29-03-2018 IPR006015 Universal stress protein A CXR48_RS04820 e7b32a78479014f0901e120a3adc68e1 166 PRINTS PR01438 Universal stress protein signature 144 166 1.5E-14 T 29-03-2018 IPR006015 Universal stress protein A CXR48_RS04820 e7b32a78479014f0901e120a3adc68e1 166 PRINTS PR01438 Universal stress protein signature 126 138 1.5E-14 T 29-03-2018 IPR006015 Universal stress protein A CXR48_RS04820 e7b32a78479014f0901e120a3adc68e1 166 Pfam PF00582 Universal stress protein family 5 166 6.6E-36 T 29-03-2018 IPR006016 UspA GO:0006950 CXR48_RS18510 7c5d1dccef453da936655ce5ec1b1707 281 SUPERFAMILY SSF101898 19 277 1.7E-5 T 29-03-2018 CXR48_RS18510 7c5d1dccef453da936655ce5ec1b1707 281 Gene3D G3DSA:2.120.10.30 18 280 4.2E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 88 100 1.7E-24 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 39 55 1.7E-24 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 143 162 1.7E-24 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 22 185 5.6E-53 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 ProSitePatterns PS00501 Signal peptidases I serine active site. 48 55 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 Gene3D G3DSA:2.10.109.10 35 191 4.4E-44 T 29-03-2018 CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 SUPERFAMILY SSF51306 37 188 8.11E-48 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 ProSitePatterns PS00761 Signal peptidases I signature 3. 148 161 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 ProSitePatterns PS00760 Signal peptidases I lysine active site. 90 102 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CXR48_RS11060 ce9bee7a0b7c182b3247cb859b3626a3 191 Pfam PF00717 Peptidase S24-like 46 112 5.2E-19 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS02840 f3750be65e5620517873a8a92d0ed2ef 411 SUPERFAMILY SSF53901 213 410 2.4E-67 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS02840 f3750be65e5620517873a8a92d0ed2ef 411 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 408 2.4E-171 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CXR48_RS02840 f3750be65e5620517873a8a92d0ed2ef 411 PIRSF PIRSF000447 1 411 1.1E-165 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CXR48_RS02840 f3750be65e5620517873a8a92d0ed2ef 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 1.8E-33 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS02840 f3750be65e5620517873a8a92d0ed2ef 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 245 8.1E-61 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS02840 f3750be65e5620517873a8a92d0ed2ef 411 Gene3D G3DSA:3.40.47.10 259 410 8.5E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS02840 f3750be65e5620517873a8a92d0ed2ef 411 SMART SM00825 Beta-ketoacyl synthase 4 411 3.6E-16 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS02840 f3750be65e5620517873a8a92d0ed2ef 411 SUPERFAMILY SSF53901 1 250 9.36E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS02840 f3750be65e5620517873a8a92d0ed2ef 411 Gene3D G3DSA:3.40.47.10 4 258 6.5E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS10515 5b11b3e3cbae37bc45fa51e2042929f8 412 Gene3D G3DSA:1.25.40.10 273 409 8.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS10515 5b11b3e3cbae37bc45fa51e2042929f8 412 SUPERFAMILY SSF53098 104 280 7.59E-27 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS10515 5b11b3e3cbae37bc45fa51e2042929f8 412 Gene3D G3DSA:3.30.420.10 93 150 0.13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS10515 5b11b3e3cbae37bc45fa51e2042929f8 412 Pfam PF13482 RNase_H superfamily 105 273 3.2E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS10515 5b11b3e3cbae37bc45fa51e2042929f8 412 Gene3D G3DSA:3.30.420.10 151 272 5.0E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS16600 519c0f9dcc2b3498006d1264b13e4e1d 228 Pfam PF00005 ABC transporter 19 165 8.0E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS16600 519c0f9dcc2b3498006d1264b13e4e1d 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 2.6E-89 T 29-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CXR48_RS16600 519c0f9dcc2b3498006d1264b13e4e1d 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS16600 519c0f9dcc2b3498006d1264b13e4e1d 228 SMART SM00382 27 221 3.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS16600 519c0f9dcc2b3498006d1264b13e4e1d 228 Gene3D G3DSA:3.40.50.300 1 226 6.4E-66 T 29-03-2018 CXR48_RS16600 519c0f9dcc2b3498006d1264b13e4e1d 228 SUPERFAMILY SSF52540 1 223 7.59E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 Gene3D G3DSA:1.10.1900.20 55 116 2.9E-29 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.05 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 4.0E-14 T 29-03-2018 CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 SUPERFAMILY SSF74731 2 116 1.24E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.8E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.8E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.8E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 4.0E-51 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS13330 bad157a078b6487f071453d0e8d18da0 119 Pfam PF00453 Ribosomal protein L20 3 109 4.4E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS10850 11f3a6d6a83d74386b316675d9796c61 349 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 38.596 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CXR48_RS10850 11f3a6d6a83d74386b316675d9796c61 349 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 7.4E-121 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CXR48_RS10850 11f3a6d6a83d74386b316675d9796c61 349 PIRSF PIRSF003314 1 340 2.1E-123 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CXR48_RS10850 11f3a6d6a83d74386b316675d9796c61 349 SUPERFAMILY SSF51395 23 346 1.92E-89 T 29-03-2018 CXR48_RS10850 11f3a6d6a83d74386b316675d9796c61 349 Gene3D G3DSA:3.20.20.70 3 342 8.6E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS10850 11f3a6d6a83d74386b316675d9796c61 349 Pfam PF01070 FMN-dependent dehydrogenase 167 324 1.7E-19 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CXR48_RS10850 11f3a6d6a83d74386b316675d9796c61 349 Pfam PF01070 FMN-dependent dehydrogenase 17 96 7.6E-6 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CXR48_RS01045 8f40783f01b48b7facff11cb37f7c426 309 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 6 299 41.255 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CXR48_RS01045 8f40783f01b48b7facff11cb37f7c426 309 Gene3D G3DSA:3.40.50.10490 14 243 6.8E-50 T 29-03-2018 CXR48_RS01045 8f40783f01b48b7facff11cb37f7c426 309 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 189 206 - T 29-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CXR48_RS01045 8f40783f01b48b7facff11cb37f7c426 309 Pfam PF01380 SIS domain 133 200 5.4E-11 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CXR48_RS01045 8f40783f01b48b7facff11cb37f7c426 309 Gene3D G3DSA:1.10.8.10 274 300 1.3E-4 T 29-03-2018 CXR48_RS01045 8f40783f01b48b7facff11cb37f7c426 309 Gene3D G3DSA:1.10.8.10 244 273 1.2E-10 T 29-03-2018 CXR48_RS01045 8f40783f01b48b7facff11cb37f7c426 309 SUPERFAMILY SSF53697 10 252 7.28E-67 T 29-03-2018 CXR48_RS01045 8f40783f01b48b7facff11cb37f7c426 309 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 10 300 9.6E-136 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CXR48_RS18145 c3bcda04a302e13e77a21bb64ee61d94 224 Pfam PF02581 Thiamine monophosphate synthase 15 198 3.9E-61 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18145 c3bcda04a302e13e77a21bb64ee61d94 224 SUPERFAMILY SSF51391 7 214 5.89E-70 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18145 c3bcda04a302e13e77a21bb64ee61d94 224 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 14 210 9.3E-69 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18145 c3bcda04a302e13e77a21bb64ee61d94 224 Gene3D G3DSA:3.20.20.70 4 216 6.5E-52 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS18145 c3bcda04a302e13e77a21bb64ee61d94 224 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 13 216 29.454 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS02975 5592a97c5b7cfb9f965ec119059ef85a 333 SUPERFAMILY SSF50129 5 145 5.33E-43 T 29-03-2018 IPR011032 GroES-like CXR48_RS02975 5592a97c5b7cfb9f965ec119059ef85a 333 Gene3D G3DSA:3.40.50.720 154 271 1.6E-13 T 29-03-2018 CXR48_RS02975 5592a97c5b7cfb9f965ec119059ef85a 333 SUPERFAMILY SSF51735 119 294 1.23E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS02975 5592a97c5b7cfb9f965ec119059ef85a 333 Gene3D G3DSA:3.90.180.10 1 153 1.4E-33 T 29-03-2018 CXR48_RS02975 5592a97c5b7cfb9f965ec119059ef85a 333 SMART SM00829 14 328 3.7E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS02975 5592a97c5b7cfb9f965ec119059ef85a 333 Pfam PF00107 Zinc-binding dehydrogenase 162 289 1.9E-14 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS02975 5592a97c5b7cfb9f965ec119059ef85a 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 90 3.5E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS02975 5592a97c5b7cfb9f965ec119059ef85a 333 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 330 5.0E-142 T 29-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CXR48_RS13825 cd605c21e3283c1ad199c3eae930104a 866 SUPERFAMILY SSF46785 797 861 6.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13825 cd605c21e3283c1ad199c3eae930104a 866 SMART SM00382 545 722 0.0067 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS13825 cd605c21e3283c1ad199c3eae930104a 866 SMART SM00843 796 861 1.8E-40 T 29-03-2018 IPR018541 FtsK gamma domain CXR48_RS13825 cd605c21e3283c1ad199c3eae930104a 866 Gene3D G3DSA:3.40.50.300 67 865 7.1E-57 T 29-03-2018 CXR48_RS13825 cd605c21e3283c1ad199c3eae930104a 866 Pfam PF01580 FtsK/SpoIIIE family 510 648 1.4E-50 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CXR48_RS13825 cd605c21e3283c1ad199c3eae930104a 866 Pfam PF09397 Ftsk gamma domain 798 859 1.4E-30 T 29-03-2018 IPR018541 FtsK gamma domain CXR48_RS13825 cd605c21e3283c1ad199c3eae930104a 866 SUPERFAMILY SSF52540 483 773 1.42E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08440 d1928d07ef5f8620563b6d38d15a5d9b 193 Pfam PF01066 CDP-alcohol phosphatidyltransferase 3 82 2.6E-18 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CXR48_RS08440 d1928d07ef5f8620563b6d38d15a5d9b 193 PIRSF PIRSF000847 1 193 3.1E-53 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CXR48_RS08440 d1928d07ef5f8620563b6d38d15a5d9b 193 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CXR48_RS08440 d1928d07ef5f8620563b6d38d15a5d9b 193 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 191 2.9E-68 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CXR48_RS05085 c6bbd8fee894f550773f32859a1f0441 346 SUPERFAMILY SSF101821 73 185 2.9E-32 T 29-03-2018 CXR48_RS05085 c6bbd8fee894f550773f32859a1f0441 346 Pfam PF05343 M42 glutamyl aminopeptidase 48 336 1.3E-87 T 29-03-2018 IPR008007 Peptidase M42 CXR48_RS05085 c6bbd8fee894f550773f32859a1f0441 346 SUPERFAMILY SSF53187 6 85 3.03E-55 T 29-03-2018 CXR48_RS05085 c6bbd8fee894f550773f32859a1f0441 346 SUPERFAMILY SSF53187 180 342 3.03E-55 T 29-03-2018 CXR48_RS05085 c6bbd8fee894f550773f32859a1f0441 346 Gene3D G3DSA:3.40.630.10 2 343 2.0E-45 T 29-03-2018 CXR48_RS05085 c6bbd8fee894f550773f32859a1f0441 346 PIRSF PIRSF001123 4 343 5.3E-40 T 29-03-2018 IPR008007 Peptidase M42 CXR48_RS16090 03b4586a1e98927c06192bd288f68550 442 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 2 442 8.5E-161 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CXR48_RS16090 03b4586a1e98927c06192bd288f68550 442 PIRSF PIRSF002746 1 442 2.5E-160 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CXR48_RS16090 03b4586a1e98927c06192bd288f68550 442 Pfam PF02447 GntP family permease 1 439 1.9E-169 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CXR48_RS18660 5c08b9e450d76d6e62c53da4aa88ac1b 115 Pfam PF06486 Protein of unknown function (DUF1093) 33 103 8.4E-21 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CXR48_RS18660 5c08b9e450d76d6e62c53da4aa88ac1b 115 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 114 4.5E-42 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CXR48_RS18660 5c08b9e450d76d6e62c53da4aa88ac1b 115 SUPERFAMILY SSF159121 29 115 4.97E-27 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CXR48_RS03465 6186fb4eec32be5b3657df6e6ea3ee72 153 TIGRFAM TIGR01741 staph_tand_hypo: conserved hypothetical protein 1 147 6.8E-50 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03465 6186fb4eec32be5b3657df6e6ea3ee72 153 SUPERFAMILY SSF160424 1 151 1.7E-51 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03465 6186fb4eec32be5b3657df6e6ea3ee72 153 Pfam PF04634 Protein of unknown function, DUF600 1 145 1.7E-51 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03465 6186fb4eec32be5b3657df6e6ea3ee72 153 Gene3D G3DSA:3.30.500.20 1 111 6.1E-36 T 29-03-2018 CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 Gene3D G3DSA:3.40.1390.20 69 189 1.5E-27 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 SMART SM00116 259 307 2.0E-8 T 29-03-2018 IPR000644 CBS domain CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 SMART SM00116 200 248 8.2 T 29-03-2018 IPR000644 CBS domain CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 Pfam PF03061 Thioesterase superfamily 352 424 1.4E-9 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 SUPERFAMILY SSF75138 72 185 7.72E-29 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 SUPERFAMILY SSF54631 182 306 2.02E-29 T 29-03-2018 CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 SUPERFAMILY SSF54637 334 425 1.28E-16 T 29-03-2018 IPR029069 HotDog domain CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 Gene3D G3DSA:3.10.129.10 301 437 3.0E-22 T 29-03-2018 CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 Gene3D G3DSA:3.10.580.10 190 300 8.7E-27 T 29-03-2018 CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 SUPERFAMILY SSF46785 5 54 3.36E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 Gene3D G3DSA:1.10.10.10 5 68 1.2E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 Pfam PF00571 CBS domain 191 244 5.5E-6 T 29-03-2018 IPR000644 CBS domain CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 Pfam PF00571 CBS domain 253 307 1.3E-8 T 29-03-2018 IPR000644 CBS domain CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 58 5.0E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS13555 e0b3828dc1716a7c326df33b8518440d 438 Pfam PF07085 DRTGG domain 76 178 2.1E-28 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 541 2.7E-213 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 Gene3D G3DSA:1.10.730.10 505 674 1.1E-8 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 676 27.499 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 243 258 3.3E-38 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 3.3E-38 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 3.3E-38 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 3.3E-38 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 315 331 3.3E-38 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 SUPERFAMILY SSF109604 338 492 2.04E-18 T 29-03-2018 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 676 5.1E-296 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12125 d6b5948bf1f64c7bcdbaf3320ddd395a 679 Pfam PF05746 DALR anticodon binding domain 576 669 9.2E-8 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CXR48_RS17660 edbe54ec37772b325784c5deb97b7f90 142 Pfam PF09148 Domain of unknown function (DUF1934) 9 134 3.7E-30 T 29-03-2018 IPR015231 Protein of unknown function DUF1934 CXR48_RS17660 edbe54ec37772b325784c5deb97b7f90 142 SUPERFAMILY SSF50814 1 138 3.07E-38 T 29-03-2018 IPR012674 Calycin CXR48_RS17660 edbe54ec37772b325784c5deb97b7f90 142 Gene3D G3DSA:2.40.128.20 1 142 1.6E-37 T 29-03-2018 IPR012674 Calycin CXR48_RS03020 59b53b2b499db9449d9827d57a314cef 325 Pfam PF02769 AIR synthase related protein, C-terminal domain 151 301 4.7E-10 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03020 59b53b2b499db9449d9827d57a314cef 325 SUPERFAMILY SSF55326 3 140 2.97E-33 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03020 59b53b2b499db9449d9827d57a314cef 325 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 324 2.2E-110 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CXR48_RS03020 59b53b2b499db9449d9827d57a314cef 325 Gene3D G3DSA:3.90.650.10 146 325 3.9E-37 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS03020 59b53b2b499db9449d9827d57a314cef 325 Pfam PF00586 AIR synthase related protein, N-terminal domain 26 139 8.7E-21 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03020 59b53b2b499db9449d9827d57a314cef 325 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 321 31.157 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CXR48_RS03020 59b53b2b499db9449d9827d57a314cef 325 Gene3D G3DSA:3.30.1330.10 5 145 2.8E-29 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CXR48_RS03020 59b53b2b499db9449d9827d57a314cef 325 PIRSF PIRSF005303 1 324 2.1E-102 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CXR48_RS03020 59b53b2b499db9449d9827d57a314cef 325 SUPERFAMILY SSF56042 146 307 1.79E-28 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CXR48_RS19405 069c1cfe53a23e7f13307a0f7290b30b 239 PIRSF PIRSF003078 2 220 1.8E-55 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CXR48_RS19405 069c1cfe53a23e7f13307a0f7290b30b 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 27.828 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CXR48_RS19405 069c1cfe53a23e7f13307a0f7290b30b 239 Gene3D G3DSA:3.40.50.150 1 238 2.8E-39 T 29-03-2018 CXR48_RS19405 069c1cfe53a23e7f13307a0f7290b30b 239 Pfam PF02527 rRNA small subunit methyltransferase G 21 204 4.5E-59 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CXR48_RS19405 069c1cfe53a23e7f13307a0f7290b30b 239 SUPERFAMILY SSF53335 1 237 2.23E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS19405 069c1cfe53a23e7f13307a0f7290b30b 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 216 1.9E-49 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CXR48_RS06525 1c3c804df380eb280ff93879a7642448 136 Gene3D G3DSA:2.20.25.10 1 42 2.7E-12 T 29-03-2018 CXR48_RS06525 1c3c804df380eb280ff93879a7642448 136 Pfam PF02566 OsmC-like protein 39 134 9.1E-20 T 29-03-2018 IPR003718 OsmC/Ohr family CXR48_RS06525 1c3c804df380eb280ff93879a7642448 136 Gene3D G3DSA:3.30.300.20 43 136 1.4E-25 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS06525 1c3c804df380eb280ff93879a7642448 136 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 3 134 4.2E-51 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CXR48_RS06525 1c3c804df380eb280ff93879a7642448 136 SUPERFAMILY SSF82784 3 135 3.27E-39 T 29-03-2018 IPR003718 OsmC/Ohr family CXR48_RS12705 bb306bbfb52f1a2ec7d9bb54219a4eb2 424 SUPERFAMILY SSF52954 329 419 1.66E-25 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS12705 bb306bbfb52f1a2ec7d9bb54219a4eb2 424 SUPERFAMILY SSF55681 3 317 2.11E-97 T 29-03-2018 CXR48_RS12705 bb306bbfb52f1a2ec7d9bb54219a4eb2 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 409 5.8E-159 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CXR48_RS12705 bb306bbfb52f1a2ec7d9bb54219a4eb2 424 Gene3D G3DSA:3.40.50.800 327 424 2.9E-22 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS12705 bb306bbfb52f1a2ec7d9bb54219a4eb2 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 34.755 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CXR48_RS12705 bb306bbfb52f1a2ec7d9bb54219a4eb2 424 PIRSF PIRSF001549 1 422 1.4E-120 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CXR48_RS12705 bb306bbfb52f1a2ec7d9bb54219a4eb2 424 Pfam PF03129 Anticodon binding domain 331 420 2.3E-19 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS12705 bb306bbfb52f1a2ec7d9bb54219a4eb2 424 Pfam PF13393 Histidyl-tRNA synthetase 8 313 4.1E-50 T 29-03-2018 CXR48_RS12705 bb306bbfb52f1a2ec7d9bb54219a4eb2 424 Gene3D G3DSA:3.30.930.10 1 324 1.0E-73 T 29-03-2018 CXR48_RS13695 b549857dcbd9aa0b4c01c1132db9ec34 456 PIRSF PIRSF036492 1 456 2.6E-186 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CXR48_RS13695 b549857dcbd9aa0b4c01c1132db9ec34 456 Gene3D G3DSA:3.40.605.10 2 228 8.4E-73 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS13695 b549857dcbd9aa0b4c01c1132db9ec34 456 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 237 248 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS13695 b549857dcbd9aa0b4c01c1132db9ec34 456 Gene3D G3DSA:3.40.309.10 229 408 8.6E-67 T 29-03-2018 CXR48_RS13695 b549857dcbd9aa0b4c01c1132db9ec34 456 Pfam PF00171 Aldehyde dehydrogenase family 7 428 1.3E-97 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS13695 b549857dcbd9aa0b4c01c1132db9ec34 456 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 209 216 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS13695 b549857dcbd9aa0b4c01c1132db9ec34 456 SUPERFAMILY SSF53720 7 442 1.06E-130 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 230 250 5.5E-79 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 9 25 5.5E-79 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 252 272 5.5E-79 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 38 64 5.5E-79 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 118 141 5.5E-79 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 276 302 5.5E-79 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 199 224 5.5E-79 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 Pfam PF14841 FliG middle domain 119 193 7.6E-31 T 29-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 Pfam PF14842 FliG N-terminal domain 8 111 5.1E-36 T 29-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 PIRSF PIRSF003161 3 338 1.0E-126 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 1 338 6.8E-164 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 SUPERFAMILY SSF48029 9 104 2.62E-20 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 Pfam PF01706 FliG C-terminal domain 222 328 1.9E-42 T 29-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 SUPERFAMILY SSF48029 118 329 6.54E-70 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 Gene3D G3DSA:1.10.220.30 87 196 6.3E-21 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 Gene3D G3DSA:1.10.220.30 9 86 8.3E-12 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CXR48_RS08085 d3855dc326f32b7d4f12b587b36cc9f6 338 Gene3D G3DSA:1.10.220.30 199 338 3.1E-36 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Gene3D G3DSA:1.10.1420.10 395 523 1.5E-31 T 29-03-2018 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 SUPERFAMILY SSF53150 114 266 1.57E-28 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Pfam PF05188 MutS domain II 125 239 3.8E-12 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 SMART SM00533 270 578 2.8E-114 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Gene3D G3DSA:3.40.50.300 555 825 1.9E-45 T 29-03-2018 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 852 25.473 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 PIRSF PIRSF037677 161 840 1.0E-129 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 PIRSF PIRSF037677 1 185 1.0E-32 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Gene3D G3DSA:1.10.1420.10 249 394 1.3E-36 T 29-03-2018 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Gene3D G3DSA:3.40.1170.10 1 128 1.5E-48 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 858 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 SUPERFAMILY SSF55271 2 112 1.44E-42 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Pfam PF05192 MutS domain III 258 547 3.1E-45 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 SUPERFAMILY SSF52540 555 786 4.7E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 SMART SM00534 595 782 8.4E-125 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Gene3D G3DSA:3.30.420.110 129 248 2.7E-14 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 SUPERFAMILY SSF48334 253 552 1.44E-87 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Pfam PF00488 MutS domain V 599 785 4.4E-85 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 676 692 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Pfam PF01624 MutS domain I 5 116 6.0E-47 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CXR48_RS08500 4877fd9ead4de3fa26fc0e79515a6904 861 Pfam PF05190 MutS family domain IV 415 506 4.9E-29 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CXR48_RS06990 a116719040b6f2a654f5d91ea4714386 147 Gene3D G3DSA:3.10.580.10 1 147 2.7E-18 T 29-03-2018 CXR48_RS06990 a116719040b6f2a654f5d91ea4714386 147 SUPERFAMILY SSF54631 13 139 2.12E-28 T 29-03-2018 CXR48_RS07485 a8901665e5750827cae1bc941230939d 184 Gene3D G3DSA:3.40.50.150 1 184 1.6E-32 T 29-03-2018 CXR48_RS07485 a8901665e5750827cae1bc941230939d 184 PIRSF PIRSF004553 1 183 2.5E-50 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CXR48_RS07485 a8901665e5750827cae1bc941230939d 184 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CXR48_RS07485 a8901665e5750827cae1bc941230939d 184 Pfam PF03602 Conserved hypothetical protein 95 1 181 5.5E-58 T 29-03-2018 CXR48_RS07485 a8901665e5750827cae1bc941230939d 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 181 5.9E-61 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CXR48_RS07485 a8901665e5750827cae1bc941230939d 184 SUPERFAMILY SSF53335 1 181 3.83E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS00920 bfc15e1427a3fe73e8d0a2214ae011ec 157 Gene3D G3DSA:1.20.120.450 1 154 1.9E-23 T 29-03-2018 CXR48_RS00920 bfc15e1427a3fe73e8d0a2214ae011ec 157 SUPERFAMILY SSF109854 2 132 3.3E-28 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CXR48_RS00920 bfc15e1427a3fe73e8d0a2214ae011ec 157 Pfam PF05163 DinB family 3 146 3.9E-29 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CXR48_RS07020 e0805333af8c7086583c9eb4067a3167 374 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 6 361 1.1E-89 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CXR48_RS07020 e0805333af8c7086583c9eb4067a3167 374 Pfam PF01546 Peptidase family M20/M25/M40 66 368 6.2E-24 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS07020 e0805333af8c7086583c9eb4067a3167 374 PIRSF PIRSF005962 1 374 2.0E-108 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CXR48_RS07020 e0805333af8c7086583c9eb4067a3167 374 Pfam PF07687 Peptidase dimerisation domain 179 269 4.4E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS07020 e0805333af8c7086583c9eb4067a3167 374 Gene3D G3DSA:3.40.630.10 2 272 9.9E-55 T 29-03-2018 CXR48_RS07020 e0805333af8c7086583c9eb4067a3167 374 SUPERFAMILY SSF55031 178 282 1.83E-28 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS07020 e0805333af8c7086583c9eb4067a3167 374 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 3 372 63.022 T 29-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 CXR48_RS07020 e0805333af8c7086583c9eb4067a3167 374 SUPERFAMILY SSF53187 3 189 1.35E-67 T 29-03-2018 CXR48_RS07020 e0805333af8c7086583c9eb4067a3167 374 SUPERFAMILY SSF53187 290 372 1.35E-67 T 29-03-2018 CXR48_RS16565 6e3435b403600cf1d2b5a16c9a3f2da9 445 SUPERFAMILY SSF103473 3 190 5.23E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS16565 6e3435b403600cf1d2b5a16c9a3f2da9 445 SUPERFAMILY SSF103473 239 432 5.23E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS16565 6e3435b403600cf1d2b5a16c9a3f2da9 445 Gene3D G3DSA:1.20.1250.20 3 193 2.4E-32 T 29-03-2018 CXR48_RS16565 6e3435b403600cf1d2b5a16c9a3f2da9 445 Pfam PF07690 Major Facilitator Superfamily 13 185 2.8E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS16565 6e3435b403600cf1d2b5a16c9a3f2da9 445 Pfam PF07690 Major Facilitator Superfamily 263 428 5.7E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS16565 6e3435b403600cf1d2b5a16c9a3f2da9 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 5.0E-6 T 29-03-2018 CXR48_RS16565 6e3435b403600cf1d2b5a16c9a3f2da9 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 5.0E-6 T 29-03-2018 CXR48_RS16565 6e3435b403600cf1d2b5a16c9a3f2da9 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 5.0E-6 T 29-03-2018 CXR48_RS16565 6e3435b403600cf1d2b5a16c9a3f2da9 445 Gene3D G3DSA:1.20.1250.20 250 444 1.8E-26 T 29-03-2018 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 SUPERFAMILY SSF50249 4 108 2.1E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 2.8E-17 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 Pfam PF02938 GAD domain 314 408 3.5E-32 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 587 34.77 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 Gene3D G3DSA:2.40.50.140 3 111 2.9E-28 T 29-03-2018 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 2 588 5.0E-271 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 SUPERFAMILY SSF55261 295 422 9.65E-44 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 1.3E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 208 1.3E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 1.3E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 213 226 1.3E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 SUPERFAMILY SSF55681 118 298 1.91E-106 T 29-03-2018 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 SUPERFAMILY SSF55681 427 587 1.91E-106 T 29-03-2018 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 Gene3D G3DSA:3.30.930.10 137 317 1.2E-54 T 29-03-2018 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 Gene3D G3DSA:3.30.930.10 370 589 5.3E-54 T 29-03-2018 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 560 5.1E-108 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS12700 96257d3a166405b882c42e5fdbeae712 592 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 299 411 0.005 T 29-03-2018 CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 188 216 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 239 3.1E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 53 70 3.1E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 3.1E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 260 280 3.1E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 191 3.1E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 220 3.1E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 61 296 2.3E-53 T 29-03-2018 CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 SUPERFAMILY SSF51735 50 296 2.4E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS03620 5fd4f2f25227d917238634edbd1c7fd3 299 Gene3D G3DSA:3.40.50.720 3 298 1.0E-70 T 29-03-2018 CXR48_RS16430 ffac5477dec837936a4befc8c3388a0a 252 Pfam PF00977 Histidine biosynthesis protein 5 235 3.2E-84 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CXR48_RS16430 ffac5477dec837936a4befc8c3388a0a 252 Gene3D G3DSA:3.20.20.70 4 248 1.7E-62 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS16430 ffac5477dec837936a4befc8c3388a0a 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 3.4E-117 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CXR48_RS16430 ffac5477dec837936a4befc8c3388a0a 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 47.233 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CXR48_RS16430 ffac5477dec837936a4befc8c3388a0a 252 SUPERFAMILY SSF51366 1 252 3.3E-78 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 Pfam PF11962 Peptidase_G2, IMC autoproteolytic cleavage domain 636 850 5.1E-69 T 29-03-2018 IPR021865 Peptidase G2, IMC autoproteolytic cleavage domain CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 SMART SM00710 276 298 990.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 SMART SM00710 333 354 130.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 SMART SM00710 299 331 90.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 SMART SM00710 487 509 2700.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 Gene3D G3DSA:2.160.20.10 109 552 8.7E-57 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 Gene3D G3DSA:2.160.10.20 553 679 2.5E-43 T 29-03-2018 CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 Gene3D G3DSA:4.10.80.40 749 767 5.7E-13 T 29-03-2018 CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 Pfam PF12708 Pectate lyase superfamily protein 121 350 6.3E-16 T 29-03-2018 IPR024535 Pectate lyase superfamily protein CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 SUPERFAMILY SSF51126 118 407 1.98E-33 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 Gene3D G3DSA:2.40.300.10 687 748 6.8E-18 T 29-03-2018 CXR48_RS10245 189008f4bf65bbff5164c4479f224d3a 854 Gene3D G3DSA:2.40.300.10 768 843 1.0E-24 T 29-03-2018 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 91 163 5.7E-17 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 95 688 1.1E-173 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 Gene3D G3DSA:3.20.70.20 71 692 4.8E-154 T 29-03-2018 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 Pfam PF02867 Ribonucleotide reductase, barrel domain 168 616 3.5E-121 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 SUPERFAMILY SSF51998 167 689 1.95E-166 T 29-03-2018 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 Pfam PF08343 Ribonucleotide reductase N-terminal 9 89 2.6E-29 T 29-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 1.2E-27 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 1.2E-27 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 243 262 1.2E-27 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 1.2E-27 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 420 443 1.2E-27 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 1.2E-27 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 SUPERFAMILY SSF48168 8 166 5.36E-50 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08670 49dd853658d9c4545e610f55a787556a 700 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 8 700 0.0 T 29-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS06560 ac2ee3341f074d5d7655d950f2bc1fb1 762 SUPERFAMILY SSF51726 6 386 1.09E-90 T 29-03-2018 CXR48_RS06560 ac2ee3341f074d5d7655d950f2bc1fb1 762 Gene3D G3DSA:3.20.20.210 4 388 8.4E-120 T 29-03-2018 CXR48_RS06560 ac2ee3341f074d5d7655d950f2bc1fb1 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 4 757 33.901 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CXR48_RS06560 ac2ee3341f074d5d7655d950f2bc1fb1 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 6 309 9.0E-116 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CXR48_RS06560 ac2ee3341f074d5d7655d950f2bc1fb1 762 PIRSF PIRSF000382 3 761 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CXR48_RS06560 ac2ee3341f074d5d7655d950f2bc1fb1 762 SUPERFAMILY SSF51726 397 756 5.89E-115 T 29-03-2018 CXR48_RS06560 ac2ee3341f074d5d7655d950f2bc1fb1 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 9 757 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CXR48_RS06560 ac2ee3341f074d5d7655d950f2bc1fb1 762 Gene3D G3DSA:3.20.20.210 389 758 1.0E-118 T 29-03-2018 CXR48_RS06560 ac2ee3341f074d5d7655d950f2bc1fb1 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 430 752 4.7E-156 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CXR48_RS01225 9a204f0ffbe4b3236f3685c385f9f551 347 Gene3D G3DSA:1.10.10.10 12 104 6.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01225 9a204f0ffbe4b3236f3685c385f9f551 347 SUPERFAMILY SSF53335 103 344 2.62E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS01225 9a204f0ffbe4b3236f3685c385f9f551 347 Gene3D G3DSA:3.40.50.150 105 347 1.3E-30 T 29-03-2018 CXR48_RS01225 9a204f0ffbe4b3236f3685c385f9f551 347 Pfam PF00891 O-methyltransferase 111 330 9.6E-46 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CXR48_RS01225 9a204f0ffbe4b3236f3685c385f9f551 347 SUPERFAMILY SSF46785 17 97 2.28E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01225 9a204f0ffbe4b3236f3685c385f9f551 347 PIRSF PIRSF005739 1 346 2.0E-52 T 29-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CXR48_RS01225 9a204f0ffbe4b3236f3685c385f9f551 347 Pfam PF16864 Dimerisation domain 20 95 2.6E-9 T 29-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 Gene3D G3DSA:2.40.50.140 129 184 6.3E-27 T 29-03-2018 CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 Gene3D G3DSA:2.40.50.140 65 126 1.2E-23 T 29-03-2018 CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 SMART SM01185 67 121 3.3E-23 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 50.469 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 Gene3D G3DSA:2.30.30.30 2 61 1.8E-27 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 3.0E-80 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 SMART SM00841 129 184 2.1E-33 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 119 2.0E-19 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 SUPERFAMILY SSF50104 1 62 4.63E-22 T 29-03-2018 IPR008991 Translation protein SH3-like domain CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 2.5E-26 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 SUPERFAMILY SSF50249 128 185 1.37E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 PIRSF PIRSF005901 1 185 2.3E-71 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 7.3E-29 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like CXR48_RS11745 e7d5c25c156790baf4407ac5921f744f 185 SUPERFAMILY SSF50249 65 129 9.94E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 460 565 5.6E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Pfam PF14765 Polyketide synthase dehydratase 715 992 4.2E-39 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 340 457 1.6E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 SMART SM01294 1523 1582 0.0094 T 29-03-2018 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Pfam PF08659 KR domain 1231 1418 3.1E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Gene3D G3DSA:3.40.47.10 347 507 2.8E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1231 1419 1.1E-37 T 29-03-2018 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 SUPERFAMILY SSF51735 997 1213 2.56E-9 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 79 332 5.0E-67 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 SUPERFAMILY SSF53901 227 456 1.43E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 SUPERFAMILY SSF53901 77 199 1.43E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Gene3D G3DSA:3.10.129.10 706 823 8.3E-10 T 29-03-2018 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 SUPERFAMILY SSF51735 1229 1461 1.82E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Gene3D G3DSA:3.40.50.720 1224 1492 2.5E-43 T 29-03-2018 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 SMART SM00825 Beta-ketoacyl synthase 80 509 6.3E-168 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Gene3D G3DSA:1.10.1200.10 1513 1608 7.1E-17 T 29-03-2018 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Gene3D G3DSA:3.40.47.10 70 344 1.3E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 244 260 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 SUPERFAMILY SSF47336 1513 1583 2.49E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01205 52cd28a5dd35396758142977ea5b7643 1630 Pfam PF00550 Phosphopantetheine attachment site 1519 1582 4.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS05685 438d04e311b1bb2e8050a94ed2ea478f 191 Gene3D G3DSA:2.40.320.10 2 190 3.5E-31 T 29-03-2018 CXR48_RS05685 438d04e311b1bb2e8050a94ed2ea478f 191 SMART SM01118 4 189 9.2E-24 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CXR48_RS05685 438d04e311b1bb2e8050a94ed2ea478f 191 SUPERFAMILY SSF55154 5 186 4.41E-30 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CXR48_RS05685 438d04e311b1bb2e8050a94ed2ea478f 191 PIRSF PIRSF012526 1 190 8.5E-70 T 29-03-2018 IPR009195 Uncharacterised protein family YjbK CXR48_RS05685 438d04e311b1bb2e8050a94ed2ea478f 191 Pfam PF01928 CYTH domain 4 183 1.4E-30 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CXR48_RS15265 930ec831aaf11cbd17287b559923900b 147 Gene3D G3DSA:3.90.1010.10 4 141 2.6E-50 T 29-03-2018 CXR48_RS15265 930ec831aaf11cbd17287b559923900b 147 Pfam PF01592 NifU-like N terminal domain 11 128 3.1E-39 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CXR48_RS15265 930ec831aaf11cbd17287b559923900b 147 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 7 140 3.4E-58 T 29-03-2018 CXR48_RS15265 930ec831aaf11cbd17287b559923900b 147 SUPERFAMILY SSF82649 2 142 2.88E-51 T 29-03-2018 CXR48_RS01340 18a175b3582c7c08689b7a2277cabc94 355 SUPERFAMILY SSF56752 3 352 9.03E-113 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS01340 18a175b3582c7c08689b7a2277cabc94 355 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 43 355 6.3E-131 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CXR48_RS01340 18a175b3582c7c08689b7a2277cabc94 355 Pfam PF01063 Amino-transferase class IV 68 310 3.4E-35 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS01340 18a175b3582c7c08689b7a2277cabc94 355 PIRSF PIRSF006468 2 355 8.3E-127 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CXR48_RS01340 18a175b3582c7c08689b7a2277cabc94 355 Gene3D G3DSA:3.30.470.10 2 172 1.2E-66 T 29-03-2018 CXR48_RS01340 18a175b3582c7c08689b7a2277cabc94 355 Gene3D G3DSA:3.20.10.10 173 338 4.2E-50 T 29-03-2018 CXR48_RS01340 18a175b3582c7c08689b7a2277cabc94 355 ProSitePatterns PS00770 Aminotransferases class-IV signature. 232 261 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS11290 3eb11f71c2ef72d127437bf41e195699 319 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 91 245 3.5E-14 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CXR48_RS11290 3eb11f71c2ef72d127437bf41e195699 319 Gene3D G3DSA:3.40.50.300 9 318 4.9E-48 T 29-03-2018 CXR48_RS11290 3eb11f71c2ef72d127437bf41e195699 319 PIRSF PIRSF000545 1 319 8.5E-140 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CXR48_RS11290 3eb11f71c2ef72d127437bf41e195699 319 SUPERFAMILY SSF52540 10 317 6.46E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11290 3eb11f71c2ef72d127437bf41e195699 319 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 11 318 8.2E-162 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CXR48_RS11290 3eb11f71c2ef72d127437bf41e195699 319 Hamap MF_00215 Pantothenate kinase [coaA]. 1 319 155.136 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CXR48_RS16465 5be547f8d6f237922421b43e8dd1006e 241 Gene3D G3DSA:3.90.70.10 65 241 2.9E-25 T 29-03-2018 CXR48_RS16465 5be547f8d6f237922421b43e8dd1006e 241 Pfam PF13529 Peptidase_C39 like family 53 213 1.3E-42 T 29-03-2018 CXR48_RS16465 5be547f8d6f237922421b43e8dd1006e 241 PIRSF PIRSF032442 1 241 3.2E-74 T 29-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 CXR48_RS11990 8fddd96e3839e36eda919d6a0c9ecb46 294 Gene3D G3DSA:1.10.3720.10 1 281 1.8E-38 T 29-03-2018 CXR48_RS11990 8fddd96e3839e36eda919d6a0c9ecb46 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 286 1.2E-77 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CXR48_RS11990 8fddd96e3839e36eda919d6a0c9ecb46 294 SUPERFAMILY SSF161098 17 277 2.43E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS11990 8fddd96e3839e36eda919d6a0c9ecb46 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 292 2.9E-51 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS13630 a8bf16e848e40f9987371b79fae66e0f 528 Gene3D G3DSA:3.40.50.980 13 179 1.3E-35 T 29-03-2018 CXR48_RS13630 a8bf16e848e40f9987371b79fae66e0f 528 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 509 1.7E-23 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS13630 a8bf16e848e40f9987371b79fae66e0f 528 Gene3D G3DSA:2.30.38.10 330 415 1.4E-20 T 29-03-2018 CXR48_RS13630 a8bf16e848e40f9987371b79fae66e0f 528 SUPERFAMILY SSF56801 23 520 1.27E-141 T 29-03-2018 CXR48_RS13630 a8bf16e848e40f9987371b79fae66e0f 528 Gene3D G3DSA:3.30.300.30 416 528 1.3E-29 T 29-03-2018 CXR48_RS13630 a8bf16e848e40f9987371b79fae66e0f 528 Gene3D G3DSA:3.40.50.980 180 329 1.2E-40 T 29-03-2018 CXR48_RS13630 a8bf16e848e40f9987371b79fae66e0f 528 Pfam PF00501 AMP-binding enzyme 24 422 5.9E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS13630 a8bf16e848e40f9987371b79fae66e0f 528 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 PIRSF PIRSF004862 1 536 1.6E-113 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 Pfam PF01514 Secretory protein of YscJ/FliF family 31 221 2.7E-61 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 536 5.9E-194 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 Gene3D G3DSA:1.20.5.510 433 475 0.0033 T 29-03-2018 CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 Pfam PF08345 Flagellar M-ring protein C-terminal 257 402 1.3E-24 T 29-03-2018 IPR013556 Flagellar M-ring C-terminal CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 Gene3D G3DSA:3.30.70.1530 52 114 3.5E-4 T 29-03-2018 CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 PRINTS PR01009 Flagellar M-ring protein signature 122 140 3.6E-27 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 PRINTS PR01009 Flagellar M-ring protein signature 270 288 3.6E-27 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 PRINTS PR01009 Flagellar M-ring protein signature 349 373 3.6E-27 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 PRINTS PR01009 Flagellar M-ring protein signature 154 168 3.6E-27 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CXR48_RS08080 90482b22c4a66404a33e0ba8d29c83c2 536 PRINTS PR01009 Flagellar M-ring protein signature 198 216 3.6E-27 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CXR48_RS06470 30662467c7599f7ea3ac24268ecaa057 349 Gene3D G3DSA:2.130.10.10 2 347 6.6E-44 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CXR48_RS06470 30662467c7599f7ea3ac24268ecaa057 349 Pfam PF10282 Lactonase, 7-bladed beta-propeller 7 345 1.0E-128 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CXR48_RS06470 30662467c7599f7ea3ac24268ecaa057 349 SUPERFAMILY SSF51004 11 347 1.52E-49 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 29-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 TIGRFAM TIGR01083 nth: endonuclease III 5 196 5.9E-89 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 SMART SM00478 39 187 3.3E-71 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 4.6E-24 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 PIRSF PIRSF001435 3 214 1.9E-57 T 29-03-2018 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 Gene3D G3DSA:1.10.340.30 22 118 6.4E-29 T 29-03-2018 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 SUPERFAMILY SSF48150 3 210 1.57E-72 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 Hamap MF_00942 Endonuclease III [nth]. 1 211 39.216 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 Pfam PF00633 Helix-hairpin-helix motif 100 128 9.7E-10 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 SMART SM00525 188 208 0.0026 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CXR48_RS10580 fcc1a29d2b41ac1e065b0a060b91f820 219 Gene3D G3DSA:1.10.1670.10 119 219 2.2E-33 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 Pfam PF02926 THUMP domain 30 164 5.9E-29 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 Gene3D G3DSA:3.40.50.620 175 398 1.2E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 SUPERFAMILY SSF52402 174 387 6.17E-51 T 29-03-2018 CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 SMART SM00981 74 165 4.3E-25 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 371 1.1E-66 T 29-03-2018 IPR020536 Thil, AANH domain GO:0004810 CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 SUPERFAMILY SSF143437 3 173 2.27E-54 T 29-03-2018 CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 401 164.719 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 373 9.1E-148 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 Gene3D G3DSA:3.30.70.1510 5 81 2.6E-25 T 29-03-2018 CXR48_RS13640 0d26bd46f82d93b1e069d554ce52dce9 401 Gene3D G3DSA:3.30.2300.10 82 162 1.4E-20 T 29-03-2018 CXR48_RS11555 9bc790c578c706f1ab00306a4d243cf2 301 SUPERFAMILY SSF51621 9 294 1.75E-98 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CXR48_RS11555 9bc790c578c706f1ab00306a4d243cf2 301 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CXR48_RS11555 9bc790c578c706f1ab00306a4d243cf2 301 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 16 295 1.0E-126 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CXR48_RS11555 9bc790c578c706f1ab00306a4d243cf2 301 Gene3D G3DSA:3.20.20.60 10 298 1.8E-86 T 29-03-2018 CXR48_RS11555 9bc790c578c706f1ab00306a4d243cf2 301 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 256 7.3E-55 T 29-03-2018 CXR48_RS11555 9bc790c578c706f1ab00306a4d243cf2 301 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 296 46.399 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CXR48_RS01445 46e80625b2e3f728a9a78be244998f60 240 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 3 233 16.103 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS01445 46e80625b2e3f728a9a78be244998f60 240 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 122 3.5E-34 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS01445 46e80625b2e3f728a9a78be244998f60 240 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 78 96 3.5E-34 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS01445 46e80625b2e3f728a9a78be244998f60 240 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 147 175 3.5E-34 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS01445 46e80625b2e3f728a9a78be244998f60 240 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 3.5E-34 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS01445 46e80625b2e3f728a9a78be244998f60 240 Pfam PF00902 Sec-independent protein translocase protein (TatC) 11 214 3.9E-52 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS01445 46e80625b2e3f728a9a78be244998f60 240 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 8 219 3.6E-55 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CXR48_RS01445 46e80625b2e3f728a9a78be244998f60 240 ProSitePatterns PS01218 TatC family signature. 147 166 - T 29-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site CXR48_RS07475 e42a6512cc66334f6ed1473ba9bfacda 90 PIRSF PIRSF031653 1 90 2.8E-34 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 CXR48_RS07475 e42a6512cc66334f6ed1473ba9bfacda 90 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 8.3E-31 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 CXR48_RS07475 e42a6512cc66334f6ed1473ba9bfacda 90 Hamap MF_01126 UPF0298 protein . 1 78 22.548 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 CXR48_RS02560 7d457accf0b73c30c811b7f585046449 145 Gene3D G3DSA:1.10.10.10 7 145 3.7E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02560 7d457accf0b73c30c811b7f585046449 145 SMART SM00347 29 127 1.5E-25 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS02560 7d457accf0b73c30c811b7f585046449 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.7E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS02560 7d457accf0b73c30c811b7f585046449 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.7E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS02560 7d457accf0b73c30c811b7f585046449 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.7E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS02560 7d457accf0b73c30c811b7f585046449 145 SUPERFAMILY SSF46785 5 142 8.24E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02560 7d457accf0b73c30c811b7f585046449 145 Pfam PF01047 MarR family 36 94 6.9E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS01860 c97fe1aef622622f580c9ff49247f9b6 492 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 84 108 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CXR48_RS01860 c97fe1aef622622f580c9ff49247f9b6 492 Pfam PF00854 POT family 96 460 5.6E-88 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CXR48_RS01860 c97fe1aef622622f580c9ff49247f9b6 492 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 17 488 9.3E-137 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CXR48_RS01860 c97fe1aef622622f580c9ff49247f9b6 492 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 158 170 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CXR48_RS01860 c97fe1aef622622f580c9ff49247f9b6 492 SUPERFAMILY SSF103473 228 486 3.92E-12 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01860 c97fe1aef622622f580c9ff49247f9b6 492 SUPERFAMILY SSF103473 14 208 7.06E-26 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01860 c97fe1aef622622f580c9ff49247f9b6 492 Gene3D G3DSA:1.20.1250.20 278 490 3.9E-14 T 29-03-2018 CXR48_RS01860 c97fe1aef622622f580c9ff49247f9b6 492 Gene3D G3DSA:1.20.1250.20 9 218 1.8E-26 T 29-03-2018 CXR48_RS13800 c01f11bbf40d0be0337d92573fb5c221 358 Gene3D G3DSA:1.20.59.10 1 97 3.4E-24 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CXR48_RS13800 c01f11bbf40d0be0337d92573fb5c221 358 SMART SM00830 10 89 8.3E-20 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CXR48_RS13800 c01f11bbf40d0be0337d92573fb5c221 358 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 101 1.1E-48 T 29-03-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CXR48_RS13800 c01f11bbf40d0be0337d92573fb5c221 358 Pfam PF01817 Chorismate mutase type II 10 87 2.1E-17 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CXR48_RS13800 c01f11bbf40d0be0337d92573fb5c221 358 Gene3D G3DSA:3.20.20.70 98 356 1.7E-74 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS13800 c01f11bbf40d0be0337d92573fb5c221 358 SUPERFAMILY SSF51569 26 353 1.1E-103 T 29-03-2018 CXR48_RS13800 c01f11bbf40d0be0337d92573fb5c221 358 Pfam PF00793 DAHP synthetase I family 110 354 9.8E-85 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CXR48_RS13800 c01f11bbf40d0be0337d92573fb5c221 358 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 1.2E-121 T 29-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CXR48_RS03160 f8d89bc95b1951c45b70ef6c91658fb6 643 Gene3D G3DSA:3.40.50.1110 453 643 1.3E-24 T 29-03-2018 CXR48_RS03160 f8d89bc95b1951c45b70ef6c91658fb6 643 SUPERFAMILY SSF52266 480 641 2.93E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS03160 f8d89bc95b1951c45b70ef6c91658fb6 643 Pfam PF01757 Acyltransferase family 12 327 2.8E-22 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CXR48_RS12580 a584a55fc22983ab6794918cb6a1aa61 422 Gene3D G3DSA:3.20.20.70 15 288 4.1E-7 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS12580 a584a55fc22983ab6794918cb6a1aa61 422 Pfam PF16325 Peptidase family U32 C-terminal domain 339 419 1.2E-24 T 29-03-2018 IPR032525 Peptidase family U32, C-terminal CXR48_RS12580 a584a55fc22983ab6794918cb6a1aa61 422 ProSitePatterns PS01276 Peptidase family U32 signature. 179 197 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CXR48_RS12580 a584a55fc22983ab6794918cb6a1aa61 422 Pfam PF01136 Peptidase family U32 93 323 1.3E-86 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CXR48_RS04750 0f6a3fdc083346c038895e0ddf9565ca 141 SUPERFAMILY SSF46955 11 100 2.33E-19 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS04750 0f6a3fdc083346c038895e0ddf9565ca 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 9.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS04750 0f6a3fdc083346c038895e0ddf9565ca 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 9.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS04750 0f6a3fdc083346c038895e0ddf9565ca 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 9.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS04750 0f6a3fdc083346c038895e0ddf9565ca 141 Gene3D G3DSA:1.10.1660.10 4 130 1.9E-22 T 29-03-2018 CXR48_RS04750 0f6a3fdc083346c038895e0ddf9565ca 141 Pfam PF13411 MerR HTH family regulatory protein 11 78 3.4E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS04750 0f6a3fdc083346c038895e0ddf9565ca 141 SMART SM00422 11 79 1.6E-25 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 SUPERFAMILY SSF51735 44 286 7.27E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 133 6.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 249 269 6.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 47 64 6.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 232 6.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 213 6.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 184 6.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 Gene3D G3DSA:3.40.50.720 1 288 4.4E-80 T 29-03-2018 CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 181 209 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 55 284 1.0E-65 T 29-03-2018 CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 182 2.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 194 213 2.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04710 3a209671525f2a3f3bc5b93fd50dd4b3 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 133 2.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 156 259 7.1E-45 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 PIRSF PIRSF002937 1 266 1.2E-135 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 155 265 2.0E-59 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 Gene3D G3DSA:1.10.10.10 152 262 8.4E-54 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 SUPERFAMILY SSF52172 2 126 2.99E-32 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 Gene3D G3DSA:3.40.50.2300 3 146 9.1E-32 T 29-03-2018 CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 SMART SM00448 4 119 2.9E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 Pfam PF00072 Response regulator receiver domain 6 119 7.7E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 SUPERFAMILY SSF46894 150 264 4.08E-48 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS11630 734ed62872a6fc068ef404919807bf0b 266 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 2 266 7.1E-131 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CXR48_RS02270 f16445b8af013f0ce41d9c7d76fe21f5 106 Gene3D G3DSA:2.40.50.110 16 103 1.5E-7 T 29-03-2018 CXR48_RS16455 5f22c70fe3352319c0ba548630089cc4 213 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 184 2.1E-61 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CXR48_RS16455 5f22c70fe3352319c0ba548630089cc4 213 Pfam PF01634 ATP phosphoribosyltransferase 54 204 6.2E-49 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CXR48_RS16455 5f22c70fe3352319c0ba548630089cc4 213 SUPERFAMILY SSF53850 3 207 1.54E-65 T 29-03-2018 CXR48_RS16455 5f22c70fe3352319c0ba548630089cc4 213 Gene3D G3DSA:3.40.190.10 116 176 3.1E-26 T 29-03-2018 CXR48_RS16455 5f22c70fe3352319c0ba548630089cc4 213 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 4 208 56.991 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CXR48_RS16455 5f22c70fe3352319c0ba548630089cc4 213 Gene3D G3DSA:3.40.190.10 1 115 2.4E-35 T 29-03-2018 CXR48_RS16455 5f22c70fe3352319c0ba548630089cc4 213 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CXR48_RS07205 4928e66d5e4093d42fbafc026a433a1f 61 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 32 57 6.3E-16 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS07205 4928e66d5e4093d42fbafc026a433a1f 61 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 34 56 2.2E-13 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 Pfam PF00106 short chain dehydrogenase 4 193 2.9E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 8.0E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 8.0E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 8.0E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 8.0E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.0E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 8.0E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 SUPERFAMILY SSF51735 3 243 5.58E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 Gene3D G3DSA:3.40.50.720 2 264 3.3E-60 T 29-03-2018 CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15425 b83a412e32792885a1ad6a9b213947d7 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04830 8699b45b82e0e37eb71105f7b8c080b1 673 SUPERFAMILY SSF90123 3 44 6.67E-74 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04830 8699b45b82e0e37eb71105f7b8c080b1 673 SUPERFAMILY SSF90123 139 421 6.67E-74 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04830 8699b45b82e0e37eb71105f7b8c080b1 673 Pfam PF00664 ABC transporter transmembrane region 152 386 7.5E-41 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04830 8699b45b82e0e37eb71105f7b8c080b1 673 ProSitePatterns PS00211 ABC transporters family signature. 567 581 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS04830 8699b45b82e0e37eb71105f7b8c080b1 673 SUPERFAMILY SSF52540 424 665 1.52E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04830 8699b45b82e0e37eb71105f7b8c080b1 673 SMART SM00382 455 641 1.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04830 8699b45b82e0e37eb71105f7b8c080b1 673 Gene3D G3DSA:3.40.50.300 415 671 2.5E-74 T 29-03-2018 CXR48_RS04830 8699b45b82e0e37eb71105f7b8c080b1 673 Gene3D G3DSA:1.20.1560.10 1 414 1.9E-68 T 29-03-2018 CXR48_RS04830 8699b45b82e0e37eb71105f7b8c080b1 673 Pfam PF00005 ABC transporter 446 595 1.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 Pfam PF00815 Histidinol dehydrogenase 22 421 3.7E-174 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 Gene3D G3DSA:3.40.50.1980 221 366 5.4E-68 T 29-03-2018 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 422 42.873 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 PIRSF PIRSF000099 2 425 2.1E-170 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 29 421 2.8E-170 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 224 256 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 Gene3D G3DSA:3.40.50.1980 22 220 6.5E-90 T 29-03-2018 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 SUPERFAMILY SSF53720 12 422 7.06E-90 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 PRINTS PR00083 Histidinol dehydrogenase signature 246 265 1.6E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 PRINTS PR00083 Histidinol dehydrogenase signature 165 191 1.6E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 PRINTS PR00083 Histidinol dehydrogenase signature 29 53 1.6E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 PRINTS PR00083 Histidinol dehydrogenase signature 130 156 1.6E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 PRINTS PR00083 Histidinol dehydrogenase signature 195 220 1.6E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 PRINTS PR00083 Histidinol dehydrogenase signature 356 374 1.6E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 PRINTS PR00083 Histidinol dehydrogenase signature 224 245 1.6E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS16450 c3cb1773ca09d1cde2aa7747c9dd804b 437 PRINTS PR00083 Histidinol dehydrogenase signature 315 340 1.6E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CXR48_RS01175 843f3cdac95a07295682d32e6dd66f0e 387 Gene3D G3DSA:3.40.1710.10 36 203 1.4E-16 T 29-03-2018 CXR48_RS01175 843f3cdac95a07295682d32e6dd66f0e 387 Pfam PF12698 ABC-2 family transporter protein 21 378 8.3E-36 T 29-03-2018 CXR48_RS13380 a957a256159a7ff1939a004f9f804a3c 276 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 3 262 4.3E-77 T 29-03-2018 IPR014199 Sporulation protein YtxC CXR48_RS13380 a957a256159a7ff1939a004f9f804a3c 276 PIRSF PIRSF012563 1 275 3.3E-94 T 29-03-2018 IPR014199 Sporulation protein YtxC CXR48_RS13380 a957a256159a7ff1939a004f9f804a3c 276 Pfam PF08812 YtxC-like family 51 261 1.8E-53 T 29-03-2018 IPR014199 Sporulation protein YtxC CXR48_RS03975 03063e59e0d9723e0a213e9c0d340b76 397 Gene3D G3DSA:4.10.320.10 109 162 2.1E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS03975 03063e59e0d9723e0a213e9c0d340b76 397 SUPERFAMILY SSF47005 112 156 9.81E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS03975 03063e59e0d9723e0a213e9c0d340b76 397 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 171 396 1.7E-79 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS03975 03063e59e0d9723e0a213e9c0d340b76 397 Pfam PF00364 Biotin-requiring enzyme 4 76 2.0E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CXR48_RS03975 03063e59e0d9723e0a213e9c0d340b76 397 SUPERFAMILY SSF51230 1 96 1.31E-24 T 29-03-2018 IPR011053 Single hybrid motif CXR48_RS03975 03063e59e0d9723e0a213e9c0d340b76 397 Gene3D G3DSA:3.30.559.10 163 397 9.3E-81 T 29-03-2018 CXR48_RS03975 03063e59e0d9723e0a213e9c0d340b76 397 SUPERFAMILY SSF52777 172 396 3.02E-79 T 29-03-2018 CXR48_RS03975 03063e59e0d9723e0a213e9c0d340b76 397 Pfam PF02817 e3 binding domain 117 151 8.3E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS03975 03063e59e0d9723e0a213e9c0d340b76 397 Gene3D G3DSA:2.40.50.100 2 80 3.2E-18 T 29-03-2018 CXR48_RS07105 01bfb1e45438d56f6f67ab73666f1459 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CXR48_RS07105 01bfb1e45438d56f6f67ab73666f1459 303 Pfam PF00294 pfkB family carbohydrate kinase 12 284 1.9E-61 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CXR48_RS07105 01bfb1e45438d56f6f67ab73666f1459 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 6.0E-109 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CXR48_RS07105 01bfb1e45438d56f6f67ab73666f1459 303 Gene3D G3DSA:3.40.1190.20 43 303 7.1E-44 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS07105 01bfb1e45438d56f6f67ab73666f1459 303 Gene3D G3DSA:2.20.150.10 9 42 1.6E-14 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CXR48_RS07105 01bfb1e45438d56f6f67ab73666f1459 303 SUPERFAMILY SSF53613 1 282 2.34E-68 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS07105 01bfb1e45438d56f6f67ab73666f1459 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 6.3E-108 T 29-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CXR48_RS07105 01bfb1e45438d56f6f67ab73666f1459 303 PIRSF PIRSF000535 1 303 7.2E-104 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CXR48_RS04805 8204666c5fe49fe47328a96ec8fda6fd 283 SUPERFAMILY SSF56752 2 274 3.79E-77 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS04805 8204666c5fe49fe47328a96ec8fda6fd 283 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 2 276 3.1E-133 T 29-03-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 CXR48_RS04805 8204666c5fe49fe47328a96ec8fda6fd 283 Pfam PF01063 Amino-transferase class IV 29 248 3.5E-49 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS04805 8204666c5fe49fe47328a96ec8fda6fd 283 Gene3D G3DSA:3.20.10.10 130 279 1.8E-41 T 29-03-2018 CXR48_RS04805 8204666c5fe49fe47328a96ec8fda6fd 283 Gene3D G3DSA:3.30.470.10 2 129 1.9E-29 T 29-03-2018 CXR48_RS04805 8204666c5fe49fe47328a96ec8fda6fd 283 ProSitePatterns PS00770 Aminotransferases class-IV signature. 176 205 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS15840 8123e7da8b829bceaa9ba00c905cd8e6 76 Pfam PF03840 Preprotein translocase SecG subunit 4 75 1.2E-22 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CXR48_RS15840 8123e7da8b829bceaa9ba00c905cd8e6 76 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 3.5E-24 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CXR48_RS15840 8123e7da8b829bceaa9ba00c905cd8e6 76 PRINTS PR01651 Protein-export SecG membrane protein signature 56 76 2.6E-14 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CXR48_RS15840 8123e7da8b829bceaa9ba00c905cd8e6 76 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 2.6E-14 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CXR48_RS15840 8123e7da8b829bceaa9ba00c905cd8e6 76 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 2.6E-14 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CXR48_RS04810 b4cc7c64073407452d0a0c0b7d7ed7ca 194 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 82 193 6.2E-19 T 29-03-2018 CXR48_RS04810 b4cc7c64073407452d0a0c0b7d7ed7ca 194 SUPERFAMILY SSF46689 3 83 1.16E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS04810 b4cc7c64073407452d0a0c0b7d7ed7ca 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CXR48_RS04810 b4cc7c64073407452d0a0c0b7d7ed7ca 194 SUPERFAMILY SSF48498 79 193 1.67E-24 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS04810 b4cc7c64073407452d0a0c0b7d7ed7ca 194 Gene3D G3DSA:1.10.357.10 4 193 8.8E-24 T 29-03-2018 CXR48_RS04810 b4cc7c64073407452d0a0c0b7d7ed7ca 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 1.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS07810 d8e3e35f73cddf821ba373ab14d96347 89 Hamap MF_01503 UPF0296 protein . 3 86 29.068 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CXR48_RS07810 d8e3e35f73cddf821ba373ab14d96347 89 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 78 2.0E-36 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CXR48_RS07810 d8e3e35f73cddf821ba373ab14d96347 89 Pfam PF04025 Domain of unknown function (DUF370) 5 77 2.9E-36 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CXR48_RS05645 85e0b0928d3f6ea9263e0cb33aa776cf 131 Gene3D G3DSA:3.40.30.10 1 131 2.8E-39 T 29-03-2018 CXR48_RS05645 85e0b0928d3f6ea9263e0cb33aa776cf 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 39.681 T 29-03-2018 IPR023731 Regulatory protein Spx GO:0045892 CXR48_RS05645 85e0b0928d3f6ea9263e0cb33aa776cf 131 SUPERFAMILY SSF52833 1 128 1.17E-39 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS05645 85e0b0928d3f6ea9263e0cb33aa776cf 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 6.0E-36 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CXR48_RS05645 85e0b0928d3f6ea9263e0cb33aa776cf 131 Pfam PF03960 ArsC family 5 113 1.3E-23 T 29-03-2018 IPR006660 Arsenate reductase-like CXR48_RS12155 49ddc05da5a03f73c83521910d285cb6 124 Pfam PF01219 Prokaryotic diacylglycerol kinase 19 119 2.3E-35 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CXR48_RS12155 49ddc05da5a03f73c83521910d285cb6 124 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 72 83 - T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CXR48_RS12155 49ddc05da5a03f73c83521910d285cb6 124 Gene3D G3DSA:1.10.3830.10 9 121 1.4E-40 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CXR48_RS16470 1d338ac35aa28ee71a6ed5d09e9cc551 172 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 139 8.2E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS16470 1d338ac35aa28ee71a6ed5d09e9cc551 172 SUPERFAMILY SSF51161 9 159 3.33E-32 T 29-03-2018 IPR011004 Trimeric LpxA-like CXR48_RS16470 1d338ac35aa28ee71a6ed5d09e9cc551 172 Gene3D G3DSA:2.160.10.10 20 159 1.3E-27 T 29-03-2018 CXR48_RS03830 8bdce92fb542cec04648dfa81fc1271a 253 PIRSF PIRSF031503 1 253 4.9E-80 T 29-03-2018 IPR014564 Uncharacterised conserved protein UCP031503, transmembrane CXR48_RS03830 8bdce92fb542cec04648dfa81fc1271a 253 Pfam PF07907 YibE/F-like protein 4 244 1.7E-68 T 29-03-2018 IPR012507 YibE/F-like CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 Gene3D G3DSA:3.40.190.10 88 176 8.5E-21 T 29-03-2018 CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 Gene3D G3DSA:3.40.190.10 177 261 1.9E-21 T 29-03-2018 CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 SUPERFAMILY SSF53850 90 291 7.47E-40 T 29-03-2018 CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 SUPERFAMILY SSF46785 1 82 6.53E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.9E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 Gene3D G3DSA:1.10.10.10 1 86 4.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS12475 3b244a80365952b36ea0c6bf4b2dd9f2 294 Pfam PF03466 LysR substrate binding domain 89 288 7.7E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS06550 ca192999d00573e08abc2b0952fa1c39 394 PIRSF PIRSF004925 1 389 4.4E-69 T 29-03-2018 IPR026032 Probable 3-phenylpropionic acid transporter CXR48_RS06550 ca192999d00573e08abc2b0952fa1c39 394 Gene3D G3DSA:1.20.1250.20 193 386 4.8E-13 T 29-03-2018 CXR48_RS06550 ca192999d00573e08abc2b0952fa1c39 394 SUPERFAMILY SSF103473 3 383 4.45E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS06550 ca192999d00573e08abc2b0952fa1c39 394 Gene3D G3DSA:1.20.1250.20 1 192 2.7E-11 T 29-03-2018 CXR48_RS06550 ca192999d00573e08abc2b0952fa1c39 394 Pfam PF12832 MFS_1 like family 6 357 7.9E-30 T 29-03-2018 IPR024989 Major facilitator superfamily associated domain CXR48_RS03770 3bc81c386a929e395bbe815858664e6b 249 SUPERFAMILY SSF55920 2 248 2.49E-66 T 29-03-2018 IPR000994 Peptidase M24 CXR48_RS03770 3bc81c386a929e395bbe815858664e6b 249 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 1 248 2.4E-100 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS03770 3bc81c386a929e395bbe815858664e6b 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 1.4E-17 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS03770 3bc81c386a929e395bbe815858664e6b 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 1.4E-17 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS03770 3bc81c386a929e395bbe815858664e6b 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 1.4E-17 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS03770 3bc81c386a929e395bbe815858664e6b 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 1.4E-17 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS03770 3bc81c386a929e395bbe815858664e6b 249 Gene3D G3DSA:3.90.230.10 1 249 1.7E-62 T 29-03-2018 CXR48_RS03770 3bc81c386a929e395bbe815858664e6b 249 Hamap MF_01974 Methionine aminopeptidase [map]. 1 249 34.925 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS03770 3bc81c386a929e395bbe815858664e6b 249 Pfam PF00557 Metallopeptidase family M24 11 240 8.2E-41 T 29-03-2018 IPR000994 Peptidase M24 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 89 4.4E-35 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 PRINTS PR01703 Manganese superoxide dismutase signature 161 173 4.0E-28 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 4.0E-28 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 4.0E-28 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 4.0E-28 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 4.0E-28 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 Gene3D G3DSA:1.10.287.990 20 89 5.6E-30 T 29-03-2018 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 163 170 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 194 1.2E-43 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 SUPERFAMILY SSF46609 1 90 1.96E-37 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 PIRSF PIRSF000349 1 201 2.0E-86 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS12015 e3113a74bdf3f03cdc81e40602374bbf 201 SUPERFAMILY SSF54719 91 200 4.45E-49 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 Pfam PF00689 Cation transporting ATPase, C-terminus 715 880 3.0E-52 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 SUPERFAMILY SSF81665 681 879 1.07E-134 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 SUPERFAMILY SSF81665 225 318 1.07E-134 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 SUPERFAMILY SSF81665 1 114 1.07E-134 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 Gene3D G3DSA:1.20.1110.10 654 885 2.8E-74 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 Pfam PF00702 haloacid dehalogenase-like hydrolase 322 645 1.7E-25 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 Pfam PF00122 E1-E2 ATPase 111 304 3.7E-53 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 177 3.8E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 210 346 3.2E-29 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 428 575 5.6E-20 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 599 721 7.7E-37 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 Gene3D G3DSA:3.40.1110.10 287 525 1.3E-58 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 488 506 7.9E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 631 647 7.9E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 663 688 7.9E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 603 619 7.9E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 Gene3D G3DSA:2.70.150.10 11 225 2.5E-53 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 71 3.3E-19 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 54 881 2.7E-214 T 29-03-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 SUPERFAMILY SSF56784 485 735 2.14E-67 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 SUPERFAMILY SSF56784 322 342 2.14E-67 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 Gene3D G3DSA:3.40.50.1000 526 653 1.1E-22 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 SUPERFAMILY SSF81660 331 533 8.07E-57 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 SUPERFAMILY SSF81653 114 224 3.79E-31 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 8.6E-42 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 655 667 8.6E-42 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 8.6E-42 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 551 561 8.6E-42 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 631 650 8.6E-42 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 540 8.6E-42 T 29-03-2018 CXR48_RS07800 f44e0e60a4f0d18eac81f31514161121 890 SMART SM00831 2 76 1.3E-25 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 264 385 1.4E-10 T 29-03-2018 IPR000014 PAS domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 259 1.0E-12 T 29-03-2018 IPR000014 PAS domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 96 1.3E-5 T 29-03-2018 IPR000014 PAS domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 585 1.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 538 552 1.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 556 566 1.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 591 604 1.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SMART SM00387 501 606 2.0E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SUPERFAMILY SSF55785 19 101 6.15E-11 T 29-03-2018 IPR000014 PAS domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SMART SM00388 395 458 1.3E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SUPERFAMILY SSF55785 158 263 1.74E-14 T 29-03-2018 IPR000014 PAS domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Gene3D G3DSA:1.10.287.130 386 454 4.9E-13 T 29-03-2018 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Gene3D G3DSA:3.30.450.20 15 121 9.6E-11 T 29-03-2018 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SUPERFAMILY SSF47384 392 457 2.55E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Gene3D G3DSA:3.30.565.10 459 606 1.1E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Gene3D G3DSA:3.30.450.20 263 385 4.9E-15 T 29-03-2018 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Pfam PF00989 PAS fold 267 377 8.1E-15 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Pfam PF00989 PAS fold 144 249 6.7E-15 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SUPERFAMILY SSF55785 252 378 5.93E-13 T 29-03-2018 IPR000014 PAS domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SMART SM00091 143 209 2.5E-5 T 29-03-2018 IPR000014 PAS domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SMART SM00091 267 333 2.2E-8 T 29-03-2018 IPR000014 PAS domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SMART SM00091 5 71 4.6E-6 T 29-03-2018 IPR000014 PAS domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Gene3D G3DSA:3.30.450.20 125 262 7.5E-18 T 29-03-2018 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SMART SM00086 215 255 0.19 T 29-03-2018 IPR001610 PAC motif CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SMART SM00086 74 117 31.0 T 29-03-2018 IPR001610 PAC motif CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Pfam PF08447 PAS fold 28 96 1.2E-6 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Pfam PF00512 His Kinase A (phospho-acceptor) domain 397 456 1.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 SUPERFAMILY SSF55874 449 605 1.44E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06915 a09a234d9e341eeaf89ecae1b686b2c3 606 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 501 605 2.7E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 SUPERFAMILY SSF52540 6 226 1.14E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 SUPERFAMILY SSF52540 348 395 1.14E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Pfam PF02810 SEC-C motif 821 839 7.7E-8 T 29-03-2018 IPR004027 SEC-C motif CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 781 19.621 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 SMART SM00958 226 338 3.3E-69 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 SUPERFAMILY SSF81886 571 789 2.88E-78 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 SUPERFAMILY SSF81886 817 829 2.88E-78 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Pfam PF07517 SecA DEAD-like domain 6 382 2.3E-128 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 SUPERFAMILY SSF52540 397 568 1.01E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Pfam PF01043 SecA preprotein cross-linking domain 230 338 1.3E-42 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 SUPERFAMILY SSF81767 225 348 3.01E-48 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Pfam PF07516 SecA Wing and Scaffold domain 568 778 2.5E-64 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 1.9E-245 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 ProSitePatterns PS01312 SecA family signature. 480 495 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Gene3D G3DSA:3.40.50.300 8 268 2.5E-54 T 29-03-2018 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Gene3D G3DSA:3.40.50.300 280 396 7.6E-9 T 29-03-2018 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 SMART SM00957 5 382 8.0E-283 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 PRINTS PR00906 SecA protein signature 393 406 4.0E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 PRINTS PR00906 SecA protein signature 99 113 4.0E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 PRINTS PR00906 SecA protein signature 168 188 4.0E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 PRINTS PR00906 SecA protein signature 61 85 4.0E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 PRINTS PR00906 SecA protein signature 356 373 4.0E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 PRINTS PR00906 SecA protein signature 115 125 4.0E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 PRINTS PR00906 SecA protein signature 319 341 4.0E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Gene3D G3DSA:1.10.3060.10 585 690 5.0E-30 T 29-03-2018 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Gene3D G3DSA:1.10.3060.10 691 790 6.0E-27 T 29-03-2018 CXR48_RS16620 8010d9fae7a36fff63d6dae533a47cdf 841 Gene3D G3DSA:3.40.50.300 397 584 3.3E-52 T 29-03-2018 CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 SUPERFAMILY SSF51735 3 182 1.07E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 44.532 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 Gene3D G3DSA:3.40.50.720 10 68 4.5E-4 T 29-03-2018 CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 Gene3D G3DSA:1.10.1040.10 69 330 3.8E-119 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 4.9E-150 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 2.0E-76 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 1.1E-65 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 PIRSF PIRSF000116 201 332 1.5E-16 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 PIRSF PIRSF000116 3 206 5.6E-41 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CXR48_RS13045 ac40118b8c10d3832fc143ca4afff85c 342 SUPERFAMILY SSF48179 183 332 5.61E-71 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 Gene3D G3DSA:1.10.287.950 332 416 7.5E-8 T 29-03-2018 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 Gene3D G3DSA:3.30.450.20 170 272 3.0E-15 T 29-03-2018 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 SUPERFAMILY SSF103190 92 194 2.75E-11 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 Gene3D G3DSA:1.10.287.950 417 661 7.7E-59 T 29-03-2018 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 612 5.4E-56 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 SUPERFAMILY SSF58104 390 659 5.23E-72 T 29-03-2018 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 SUPERFAMILY SSF58104 323 357 5.23E-72 T 29-03-2018 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 Pfam PF00672 HAMP domain 303 351 3.0E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 Pfam PF02743 Cache domain 48 263 2.8E-25 T 29-03-2018 IPR033479 Double Cache domain 1 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 Gene3D G3DSA:3.30.450.20 36 169 2.5E-20 T 29-03-2018 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 SMART SM00319 33 151 3.8E-26 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 SMART SM00304 303 355 1.9E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS14505 50d64b72b433f7565ef4a3c05ab8ed90 661 SMART SM00283 384 659 3.9E-93 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS01520 ea0ccaa097159a2ff704157df366c1ea 559 Pfam PF00128 Alpha amylase, catalytic domain 28 376 4.4E-118 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CXR48_RS01520 ea0ccaa097159a2ff704157df366c1ea 559 Gene3D G3DSA:2.60.40.1180 482 559 4.3E-19 T 29-03-2018 CXR48_RS01520 ea0ccaa097159a2ff704157df366c1ea 559 Gene3D G3DSA:3.20.20.80 2 481 1.1E-131 T 29-03-2018 CXR48_RS01520 ea0ccaa097159a2ff704157df366c1ea 559 SUPERFAMILY SSF51445 4 476 3.84E-151 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS01520 ea0ccaa097159a2ff704157df366c1ea 559 SMART SM00642 13 420 2.1E-154 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CXR48_RS01520 ea0ccaa097159a2ff704157df366c1ea 559 SUPERFAMILY SSF51011 481 557 7.2E-16 T 29-03-2018 CXR48_RS14615 9ceeaa7ac4dfa986bc90a556c6283422 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CXR48_RS14615 9ceeaa7ac4dfa986bc90a556c6283422 389 SUPERFAMILY SSF53383 7 387 2.02E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS14615 9ceeaa7ac4dfa986bc90a556c6283422 389 Gene3D G3DSA:3.90.1150.10 296 389 1.7E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS14615 9ceeaa7ac4dfa986bc90a556c6283422 389 Pfam PF00155 Aminotransferase class I and II 32 381 3.8E-68 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS14615 9ceeaa7ac4dfa986bc90a556c6283422 389 Gene3D G3DSA:3.40.640.10 46 295 2.6E-65 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS19200 3a65066f2b111fca5239dc17c9391fa1 212 Pfam PF00881 Nitroreductase family 14 192 4.8E-32 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CXR48_RS19200 3a65066f2b111fca5239dc17c9391fa1 212 Gene3D G3DSA:3.40.109.10 1 212 3.0E-51 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS19200 3a65066f2b111fca5239dc17c9391fa1 212 SUPERFAMILY SSF55469 9 210 4.06E-60 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS08455 54c290c6ca7e41d4287793b49768252a 393 Gene3D G3DSA:3.40.710.10 59 392 2.6E-66 T 29-03-2018 CXR48_RS08455 54c290c6ca7e41d4287793b49768252a 393 SUPERFAMILY SSF56601 84 375 2.58E-75 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS08455 54c290c6ca7e41d4287793b49768252a 393 Pfam PF00144 Beta-lactamase 97 384 4.7E-52 T 29-03-2018 IPR001466 Beta-lactamase-related CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 Gene3D G3DSA:3.90.20.20 1 133 3.9E-23 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 PRINTS PR00773 GrpE protein signature 61 77 1.4E-30 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 PRINTS PR00773 GrpE protein signature 170 189 1.4E-30 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 PRINTS PR00773 GrpE protein signature 89 104 1.4E-30 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 PRINTS PR00773 GrpE protein signature 143 158 1.4E-30 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 Gene3D G3DSA:2.30.22.10 135 191 4.3E-22 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 ProSitePatterns PS01071 grpE protein signature. 146 189 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 SUPERFAMILY SSF51064 136 191 3.79E-19 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 Hamap MF_01151 Protein GrpE [grpE]. 3 191 21.94 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 SUPERFAMILY SSF58014 40 135 4.97E-26 T 29-03-2018 CXR48_RS12240 eb876340a3c3f1964aade68dec8d6a88 191 Pfam PF01025 GrpE 28 191 1.0E-52 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CXR48_RS09210 a1f93834e70b6b291f8da410eb5cfeff 546 Gene3D G3DSA:2.30.38.10 354 437 1.8E-28 T 29-03-2018 CXR48_RS09210 a1f93834e70b6b291f8da410eb5cfeff 546 SUPERFAMILY SSF56801 5 540 1.1E-162 T 29-03-2018 CXR48_RS09210 a1f93834e70b6b291f8da410eb5cfeff 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09210 a1f93834e70b6b291f8da410eb5cfeff 546 Gene3D G3DSA:3.30.300.30 438 540 1.5E-31 T 29-03-2018 CXR48_RS09210 a1f93834e70b6b291f8da410eb5cfeff 546 Pfam PF00501 AMP-binding enzyme 13 445 1.2E-112 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09210 a1f93834e70b6b291f8da410eb5cfeff 546 Gene3D G3DSA:3.40.50.980 6 199 2.1E-42 T 29-03-2018 CXR48_RS09210 a1f93834e70b6b291f8da410eb5cfeff 546 Gene3D G3DSA:3.40.50.980 200 353 2.2E-52 T 29-03-2018 CXR48_RS09210 a1f93834e70b6b291f8da410eb5cfeff 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 529 1.1E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 Gene3D G3DSA:3.40.1190.20 1 272 7.3E-57 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 10 259 1.4E-97 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 1.8E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 164 181 1.8E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 1.8E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 1.8E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 1.8E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 1.8E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 264 33.391 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 SUPERFAMILY SSF53613 9 261 5.61E-56 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 Pfam PF02110 Hydroxyethylthiazole kinase family 10 257 9.1E-95 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS18150 988356c22bad925270825569e4ddd0d0 272 PIRSF PIRSF000513 4 269 1.2E-95 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS15760 d6edfb77d67db7ac4359c3add36c67cf 442 SUPERFAMILY SSF51679 7 431 3.01E-132 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS15760 d6edfb77d67db7ac4359c3add36c67cf 442 PIRSF PIRSF000337 2 436 1.5E-140 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CXR48_RS15760 d6edfb77d67db7ac4359c3add36c67cf 442 Pfam PF00296 Luciferase-like monooxygenase 21 379 4.2E-63 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS15760 d6edfb77d67db7ac4359c3add36c67cf 442 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 425 1.4E-160 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CXR48_RS15760 d6edfb77d67db7ac4359c3add36c67cf 442 Gene3D G3DSA:3.20.20.30 3 436 5.0E-97 T 29-03-2018 CXR48_RS11750 ad615cc7b0bc5eb11dd680d0ebc13c9c 353 SUPERFAMILY SSF55920 82 348 1.31E-81 T 29-03-2018 IPR000994 Peptidase M24 CXR48_RS11750 ad615cc7b0bc5eb11dd680d0ebc13c9c 353 Gene3D G3DSA:3.90.230.10 126 353 5.6E-79 T 29-03-2018 CXR48_RS11750 ad615cc7b0bc5eb11dd680d0ebc13c9c 353 Pfam PF00557 Metallopeptidase family M24 136 337 6.7E-66 T 29-03-2018 IPR000994 Peptidase M24 CXR48_RS11750 ad615cc7b0bc5eb11dd680d0ebc13c9c 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 4.5E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS11750 ad615cc7b0bc5eb11dd680d0ebc13c9c 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 4.5E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS11750 ad615cc7b0bc5eb11dd680d0ebc13c9c 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 274 286 4.5E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS11750 ad615cc7b0bc5eb11dd680d0ebc13c9c 353 Gene3D G3DSA:3.40.350.10 1 125 4.5E-31 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CXR48_RS11750 ad615cc7b0bc5eb11dd680d0ebc13c9c 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 127 2.6E-29 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 Gene3D G3DSA:3.60.20.10 22 444 3.1E-161 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 Pfam PF04898 Glutamate synthase central domain 464 740 4.4E-114 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 Pfam PF01645 Conserved region in glutamate synthase 799 1167 1.2E-162 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 Pfam PF00310 Glutamine amidotransferases class-II 22 438 1.1E-187 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 Gene3D G3DSA:3.20.20.70 784 1219 5.1E-160 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 SUPERFAMILY SSF56235 22 441 6.78E-152 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 Pfam PF01493 GXGXG motif 1245 1433 6.1E-84 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 SUPERFAMILY SSF69336 1214 1478 7.19E-92 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 Gene3D G3DSA:2.160.20.60 1220 1495 5.8E-109 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 Gene3D G3DSA:3.20.20.70 445 783 2.4E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS09330 0632d4da9eb73fe7d813195215094e73 1519 SUPERFAMILY SSF51395 459 1204 9.36E-263 T 29-03-2018 CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 SUPERFAMILY SSF47203 235 370 1.53E-25 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 PIRSF PIRSF016578 136 380 3.7E-27 T 29-03-2018 CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 PIRSF PIRSF016578 1 100 2.1E-11 T 29-03-2018 CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 SUPERFAMILY SSF56645 19 224 1.2E-42 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 Gene3D G3DSA:1.20.140.10 220 361 4.7E-21 T 29-03-2018 CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 Gene3D G3DSA:1.10.540.10 5 125 2.8E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 216 3.9E-13 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 360 5.5E-18 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 Gene3D G3DSA:2.40.110.10 126 219 3.8E-19 T 29-03-2018 CXR48_RS02355 c9ad1fd891276b2d1ca4d5ad731078db 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 95 5.0E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 SUPERFAMILY SSF55174 2 200 2.22E-67 T 29-03-2018 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 Gene3D G3DSA:3.10.290.10 98 140 9.4E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 SMART SM00363 92 156 2.5E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 Gene3D G3DSA:1.10.1050.10 1 97 5.4E-39 T 29-03-2018 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 Pfam PF01479 S4 domain 93 139 3.9E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 7.7E-86 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 SMART SM01390 3 91 4.3E-46 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 36.265 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 2.9E-28 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CXR48_RS13685 750f35d5e0b236b40cba6db00f78447b 200 Gene3D G3DSA:1.10.1050.10 141 200 9.4E-17 T 29-03-2018 CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 Pfam PF01476 LysM domain 4 46 2.1E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 Pfam PF01476 LysM domain 50 93 1.9E-7 T 29-03-2018 IPR018392 LysM domain CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 Pfam PF00704 Glycosyl hydrolases family 18 179 400 5.5E-27 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 SMART SM00636 101 403 2.3E-26 T 29-03-2018 IPR011583 Chitinase II GO:0008061 CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 SUPERFAMILY SSF54106 49 93 7.72E-7 T 29-03-2018 IPR018392 LysM domain CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 Gene3D G3DSA:3.20.20.80 130 412 7.0E-47 T 29-03-2018 CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 SUPERFAMILY SSF54106 2 46 1.83E-11 T 29-03-2018 IPR018392 LysM domain CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 SMART SM00257 49 93 5.5E-10 T 29-03-2018 IPR018392 LysM domain CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 SMART SM00257 3 46 1.5E-13 T 29-03-2018 IPR018392 LysM domain CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 Gene3D G3DSA:3.10.350.10 48 94 1.7E-12 T 29-03-2018 CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 SUPERFAMILY SSF51445 375 417 3.75E-45 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 SUPERFAMILY SSF51445 120 316 3.75E-45 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS06590 91d677e5ad10338120b1b68054d8f54d 420 Gene3D G3DSA:3.10.350.10 1 47 3.6E-13 T 29-03-2018 CXR48_RS06875 84702c5692d3eb35ff694687624db347 88 SUPERFAMILY SSF55594 1 83 1.57E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS06875 84702c5692d3eb35ff694687624db347 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CXR48_RS06875 84702c5692d3eb35ff694687624db347 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 6.4E-33 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS06875 84702c5692d3eb35ff694687624db347 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CXR48_RS06875 84702c5692d3eb35ff694687624db347 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.3E-26 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS06875 84702c5692d3eb35ff694687624db347 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.3E-26 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS06875 84702c5692d3eb35ff694687624db347 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.3E-26 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS06875 84702c5692d3eb35ff694687624db347 88 Gene3D G3DSA:3.30.1340.10 1 88 1.4E-33 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS06875 84702c5692d3eb35ff694687624db347 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.8E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 SUPERFAMILY SSF103190 99 193 1.99E-9 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 Pfam PF02743 Cache domain 36 259 1.6E-30 T 29-03-2018 IPR033479 Double Cache domain 1 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 Gene3D G3DSA:3.30.450.20 170 277 2.0E-18 T 29-03-2018 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 Gene3D G3DSA:1.10.287.1060 327 403 4.2E-5 T 29-03-2018 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 Gene3D G3DSA:1.10.287.950 404 571 3.4E-41 T 29-03-2018 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 Gene3D G3DSA:1.10.287.950 572 647 3.8E-4 T 29-03-2018 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 Gene3D G3DSA:3.30.450.20 29 169 4.3E-26 T 29-03-2018 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 SMART SM00283 379 640 1.5E-79 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 448 607 1.6E-34 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 SMART SM00304 298 350 2.4E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 SUPERFAMILY SSF58104 318 352 9.42E-66 T 29-03-2018 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 SUPERFAMILY SSF58104 385 653 9.42E-66 T 29-03-2018 CXR48_RS06895 47c897f8ba90ed7301b03e77130c569e 655 Pfam PF00672 HAMP domain 299 345 1.5E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS12680 5590894c71348034418f9b2bda922a15 138 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CXR48_RS12680 5590894c71348034418f9b2bda922a15 138 Gene3D G3DSA:1.10.10.10 1 138 2.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12680 5590894c71348034418f9b2bda922a15 138 SUPERFAMILY SSF46785 2 125 2.16E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12680 5590894c71348034418f9b2bda922a15 138 Pfam PF02082 Transcriptional regulator 1 82 3.8E-26 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CXR48_RS12680 5590894c71348034418f9b2bda922a15 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 124 1.3E-33 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CXR48_RS03400 ae3a27c5164e6caf4cf85187bf5e0bef 476 SUPERFAMILY SSF55931 4 294 4.71E-122 T 29-03-2018 CXR48_RS03400 ae3a27c5164e6caf4cf85187bf5e0bef 476 Gene3D G3DSA:1.10.10.410 413 474 1.0E-21 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CXR48_RS03400 ae3a27c5164e6caf4cf85187bf5e0bef 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 473 2.7E-183 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CXR48_RS03400 ae3a27c5164e6caf4cf85187bf5e0bef 476 Pfam PF02934 GatB/GatE catalytic domain 5 286 1.6E-112 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CXR48_RS03400 ae3a27c5164e6caf4cf85187bf5e0bef 476 SMART SM00845 326 473 5.8E-77 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CXR48_RS03400 ae3a27c5164e6caf4cf85187bf5e0bef 476 SUPERFAMILY SSF89095 295 400 6.93E-37 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CXR48_RS03400 ae3a27c5164e6caf4cf85187bf5e0bef 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 39.288 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CXR48_RS03400 ae3a27c5164e6caf4cf85187bf5e0bef 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CXR48_RS03400 ae3a27c5164e6caf4cf85187bf5e0bef 476 Pfam PF02637 GatB domain 326 473 2.8E-55 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CXR48_RS04855 d1fbc6da77b264a4cd9a190077efe0c1 452 Gene3D G3DSA:3.30.470.20 288 421 3.4E-12 T 29-03-2018 CXR48_RS04855 d1fbc6da77b264a4cd9a190077efe0c1 452 SUPERFAMILY SSF56059 193 251 2.87E-14 T 29-03-2018 CXR48_RS04855 d1fbc6da77b264a4cd9a190077efe0c1 452 SUPERFAMILY SSF56059 290 422 2.87E-14 T 29-03-2018 CXR48_RS04855 d1fbc6da77b264a4cd9a190077efe0c1 452 Gene3D G3DSA:3.30.1490.20 217 287 1.2E-8 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS04855 d1fbc6da77b264a4cd9a190077efe0c1 452 Pfam PF14398 YheC/D like ATP-grasp 185 439 8.7E-81 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CXR48_RS02525 3cb88ac6e4261f1ec341bbe5a438c127 174 Pfam PF02525 Flavodoxin-like fold 1 166 2.4E-44 T 29-03-2018 IPR003680 Flavodoxin-like fold CXR48_RS02525 3cb88ac6e4261f1ec341bbe5a438c127 174 SUPERFAMILY SSF52218 1 171 3.03E-47 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS02525 3cb88ac6e4261f1ec341bbe5a438c127 174 Gene3D G3DSA:3.40.50.360 1 173 1.9E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS16720 1f363c9d139bd2ecc5df195a995eb907 387 Pfam PF07730 Histidine kinase 180 248 1.7E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CXR48_RS16720 1f363c9d139bd2ecc5df195a995eb907 387 PIRSF PIRSF003169 1 386 2.1E-165 T 29-03-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 CXR48_RS16720 1f363c9d139bd2ecc5df195a995eb907 387 SUPERFAMILY SSF55874 255 383 1.05E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS16720 1f363c9d139bd2ecc5df195a995eb907 387 Gene3D G3DSA:3.30.565.10 246 385 1.2E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS16720 1f363c9d139bd2ecc5df195a995eb907 387 Pfam PF05384 Sensor protein DegS 12 170 3.9E-58 T 29-03-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 CXR48_RS16720 1f363c9d139bd2ecc5df195a995eb907 387 Gene3D G3DSA:1.20.120.570 1 165 7.3E-4 T 29-03-2018 CXR48_RS16720 1f363c9d139bd2ecc5df195a995eb907 387 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 291 384 2.6E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS16720 1f363c9d139bd2ecc5df195a995eb907 387 SMART SM00387 289 385 4.7E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS11035 15cc788283a3b84148a0f511a4cf963a 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 30.627 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS11035 15cc788283a3b84148a0f511a4cf963a 154 Gene3D G3DSA:3.40.50.960 1 154 6.5E-68 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS11035 15cc788283a3b84148a0f511a4cf963a 154 SUPERFAMILY SSF52121 3 153 1.7E-63 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS11035 15cc788283a3b84148a0f511a4cf963a 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 6.2E-61 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS11035 15cc788283a3b84148a0f511a4cf963a 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 150 1.2E-60 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 Gene3D G3DSA:1.10.150.20 523 590 6.9E-12 T 29-03-2018 CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 SMART SM00465 15 95 1.0E-24 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 569 1.2E-231 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 28.973 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 SUPERFAMILY SSF46600 182 235 3.92E-14 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 Gene3D G3DSA:3.40.1440.10 1 98 2.1E-26 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 Pfam PF01541 GIY-YIG catalytic domain 16 90 8.5E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 Gene3D G3DSA:4.10.860.10 175 235 2.6E-12 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 Pfam PF02151 UvrB/uvrC motif 198 229 3.3E-8 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 SUPERFAMILY SSF82771 14 97 4.58E-21 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 372 523 7.6E-57 T 29-03-2018 IPR001162 UvrC family homology region CXR48_RS13150 4ff16922bc6a3f0082f1ba1768956c3a 590 SUPERFAMILY SSF47781 501 589 5.72E-20 T 29-03-2018 IPR010994 RuvA domain 2-like CXR48_RS05650 b605ce4fc95ebd3027a8376c4514cfe7 218 Pfam PF03741 Integral membrane protein TerC family 12 179 6.4E-45 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CXR48_RS05650 b605ce4fc95ebd3027a8376c4514cfe7 218 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 181 3.1E-67 T 29-03-2018 IPR022301 Integral membrane protein YjbE CXR48_RS11805 fe846e67b802e5fec6b607ca87a26508 556 SUPERFAMILY SSF52540 28 258 1.78E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11805 fe846e67b802e5fec6b607ca87a26508 556 SMART SM00487 56 239 1.4E-33 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS11805 fe846e67b802e5fec6b607ca87a26508 556 SUPERFAMILY SSF52540 349 518 2.66E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11805 fe846e67b802e5fec6b607ca87a26508 556 SUPERFAMILY SSF52540 168 222 2.66E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11805 fe846e67b802e5fec6b607ca87a26508 556 Pfam PF00176 SNF2 family N-terminal domain 79 293 6.1E-34 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CXR48_RS11805 fe846e67b802e5fec6b607ca87a26508 556 Gene3D G3DSA:3.40.50.300 342 503 9.7E-37 T 29-03-2018 CXR48_RS11805 fe846e67b802e5fec6b607ca87a26508 556 Gene3D G3DSA:3.40.50.10810 36 264 8.9E-40 T 29-03-2018 CXR48_RS11805 fe846e67b802e5fec6b607ca87a26508 556 SMART SM00490 385 465 7.2E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS11805 fe846e67b802e5fec6b607ca87a26508 556 Pfam PF00271 Helicase conserved C-terminal domain 363 465 1.9E-21 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS18035 e0d2c3cdce810d6ad3fce5b0bb0b5c98 215 SUPERFAMILY SSF52540 1 215 2.03E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18035 e0d2c3cdce810d6ad3fce5b0bb0b5c98 215 SMART SM00382 26 212 4.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS18035 e0d2c3cdce810d6ad3fce5b0bb0b5c98 215 Pfam PF00005 ABC transporter 18 165 5.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS18035 e0d2c3cdce810d6ad3fce5b0bb0b5c98 215 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS18035 e0d2c3cdce810d6ad3fce5b0bb0b5c98 215 Gene3D G3DSA:3.40.50.300 1 215 2.3E-64 T 29-03-2018 CXR48_RS03340 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 Gene3D G3DSA:1.10.1270.10 1 100 3.2E-31 T 29-03-2018 CXR48_RS03340 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 SUPERFAMILY SSF48295 3 94 2.41E-32 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CXR48_RS03340 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 2.4E-49 T 29-03-2018 IPR013368 TrpR homologue YerC/YecD CXR48_RS03340 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 PIRSF PIRSF012508 1 100 1.2E-47 T 29-03-2018 IPR013368 TrpR homologue YerC/YecD CXR48_RS03340 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 Pfam PF01371 Trp repressor protein 10 94 2.5E-34 T 29-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 CXR48_RS18945 0a71cf00e672612eb4271456be4d0f76 466 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CXR48_RS18945 0a71cf00e672612eb4271456be4d0f76 466 Pfam PF00324 Amino acid permease 18 461 1.3E-126 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS18945 0a71cf00e672612eb4271456be4d0f76 466 PIRSF PIRSF006060 1 465 6.3E-91 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS11660 11dfe02feaf41fba880a12605e89c84c 296 SUPERFAMILY SSF48576 8 275 2.16E-83 T 29-03-2018 IPR008949 Isoprenoid synthase domain CXR48_RS11660 11dfe02feaf41fba880a12605e89c84c 296 Gene3D G3DSA:1.10.600.10 1 296 5.4E-86 T 29-03-2018 IPR008949 Isoprenoid synthase domain CXR48_RS11660 11dfe02feaf41fba880a12605e89c84c 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 98 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CXR48_RS11660 11dfe02feaf41fba880a12605e89c84c 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CXR48_RS11660 11dfe02feaf41fba880a12605e89c84c 296 Pfam PF00348 Polyprenyl synthetase 31 264 4.2E-59 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CXR48_RS18120 8212e9288a7d2608aa44628154cfed9e 226 Gene3D G3DSA:3.40.50.150 18 226 4.0E-33 T 29-03-2018 CXR48_RS18120 8212e9288a7d2608aa44628154cfed9e 226 Pfam PF13489 Methyltransferase domain 22 176 2.2E-16 T 29-03-2018 CXR48_RS18120 8212e9288a7d2608aa44628154cfed9e 226 SUPERFAMILY SSF53335 6 191 1.75E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS06240 185bf1460ce5800a7dbbefe8774ae660 463 Pfam PF04860 Phage portal protein 113 435 3.3E-10 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CXR48_RS06240 185bf1460ce5800a7dbbefe8774ae660 463 TIGRFAM TIGR01540 portal_PBSX: phage portal protein, PBSX family 22 393 1.5E-139 T 29-03-2018 IPR006430 Phage portal protein PBSX family CXR48_RS06240 185bf1460ce5800a7dbbefe8774ae660 463 PIRSF PIRSF019260 1 463 2.5E-171 T 29-03-2018 IPR016753 Phage portal protein PBSX family, Firmicutes CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 Gene3D G3DSA:3.90.1170.10 3 139 7.2E-55 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 8.4E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 8.4E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 8.4E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 8.4E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 SUPERFAMILY SSF54686 1 137 1.7E-59 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 5.8E-64 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.6E-53 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.632 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00770 f3527853780abeced6befc2565a4e57a 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS04485 65f2b22e8a58f4eb3e82a52d5f6a922d 154 Gene3D G3DSA:1.10.10.10 16 152 4.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04485 65f2b22e8a58f4eb3e82a52d5f6a922d 154 SUPERFAMILY SSF46785 12 145 3.35E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04485 65f2b22e8a58f4eb3e82a52d5f6a922d 154 Pfam PF01047 MarR family 38 96 2.0E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS04485 65f2b22e8a58f4eb3e82a52d5f6a922d 154 SMART SM00347 31 131 1.2E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS17990 6f182f7ebe86bf5351c5c4298a00989c 270 Gene3D G3DSA:3.40.1190.20 1 256 1.6E-57 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS17990 6f182f7ebe86bf5351c5c4298a00989c 270 SUPERFAMILY SSF53613 1 264 2.49E-75 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS17990 6f182f7ebe86bf5351c5c4298a00989c 270 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 2.5E-89 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CXR48_RS17990 6f182f7ebe86bf5351c5c4298a00989c 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 6.8E-87 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS02965 11fda8b32cb7382a0bf614f120bbab10 284 SUPERFAMILY SSF47240 1 283 1.54E-86 T 29-03-2018 IPR009078 Ferritin-like superfamily CXR48_RS02965 11fda8b32cb7382a0bf614f120bbab10 284 Gene3D G3DSA:1.20.1260.10 1 200 1.5E-60 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS02965 11fda8b32cb7382a0bf614f120bbab10 284 Pfam PF05067 Manganese containing catalase 1 276 5.0E-67 T 29-03-2018 IPR007760 Manganese catalase CXR48_RS04220 74040b1ea31ac634caa99986507c3254 157 Pfam PF00578 AhpC/TSA family 5 132 4.4E-39 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CXR48_RS04220 74040b1ea31ac634caa99986507c3254 157 PIRSF PIRSF000239 1 157 5.5E-29 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CXR48_RS04220 74040b1ea31ac634caa99986507c3254 157 SUPERFAMILY SSF52833 3 154 5.38E-52 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS04220 74040b1ea31ac634caa99986507c3254 157 Gene3D G3DSA:3.40.30.10 1 154 6.2E-41 T 29-03-2018 CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 Gene3D G3DSA:3.40.190.10 89 176 1.1E-10 T 29-03-2018 CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.5E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 Pfam PF03466 LysR substrate binding domain 88 289 3.7E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 Gene3D G3DSA:1.10.10.10 1 87 2.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 SUPERFAMILY SSF46785 1 88 2.14E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 Gene3D G3DSA:3.40.190.10 177 268 2.6E-16 T 29-03-2018 CXR48_RS01835 4f9038cd028e1343c7f9279352fc2c5f 290 SUPERFAMILY SSF53850 89 289 2.17E-32 T 29-03-2018 CXR48_RS16040 aa1ad2a9b270c7135df373d3762a7d67 344 Gene3D G3DSA:3.40.50.1360 89 343 1.8E-39 T 29-03-2018 CXR48_RS16040 aa1ad2a9b270c7135df373d3762a7d67 344 Pfam PF04198 Putative sugar-binding domain 91 337 4.7E-76 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CXR48_RS16040 aa1ad2a9b270c7135df373d3762a7d67 344 Gene3D G3DSA:1.10.10.10 17 87 3.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16040 aa1ad2a9b270c7135df373d3762a7d67 344 SUPERFAMILY SSF100950 90 337 2.93E-66 T 29-03-2018 CXR48_RS16040 aa1ad2a9b270c7135df373d3762a7d67 344 SUPERFAMILY SSF46785 19 81 6.18E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 Gene3D G3DSA:3.30.450.20 35 178 1.4E-14 T 29-03-2018 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF47384 362 443 2.16E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 555 4.9E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 599 4.9E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 541 4.9E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 580 4.9E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 Gene3D G3DSA:3.30.450.20 261 381 4.9E-17 T 29-03-2018 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 Gene3D G3DSA:1.10.287.130 382 439 2.6E-18 T 29-03-2018 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 Pfam PF00672 HAMP domain 204 252 3.1E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 Pfam PF00512 His Kinase A (phospho-acceptor) domain 377 442 1.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 489 600 7.3E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF158472 204 253 8.24E-10 T 29-03-2018 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF55785 250 368 2.62E-10 T 29-03-2018 IPR000014 PAS domain CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF103190 50 177 3.26E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 SMART SM00388 376 443 1.6E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 SMART SM00304 204 256 9.1E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 SMART SM00387 488 602 1.4E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF55874 432 600 2.1E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 Gene3D G3DSA:3.30.565.10 451 602 2.5E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 Pfam PF13426 PAS domain 274 369 1.6E-7 T 29-03-2018 IPR000014 PAS domain CXR48_RS19025 fc34b1baf322c00698fcd04cac9cb118 611 SMART SM00091 263 329 1.4E-5 T 29-03-2018 IPR000014 PAS domain CXR48_RS09185 c19f8b6be8c1536c5516865b4a5dd37e 509 Gene3D G3DSA:3.90.226.10 2 247 3.3E-61 T 29-03-2018 CXR48_RS09185 c19f8b6be8c1536c5516865b4a5dd37e 509 SUPERFAMILY SSF52096 8 249 8.25E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS09185 c19f8b6be8c1536c5516865b4a5dd37e 509 SUPERFAMILY SSF52096 236 508 8.86E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS09185 c19f8b6be8c1536c5516865b4a5dd37e 509 Pfam PF01039 Carboxyl transferase domain 26 506 6.2E-161 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CXR48_RS09185 c19f8b6be8c1536c5516865b4a5dd37e 509 Gene3D G3DSA:3.90.226.10 248 507 6.4E-68 T 29-03-2018 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.8E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.8E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.8E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.8E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 PIRSF PIRSF006641 1 366 2.6E-167 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 Gene3D G3DSA:3.40.50.300 1 80 8.3E-8 T 29-03-2018 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 SUPERFAMILY SSF81271 282 363 4.58E-36 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 47.181 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 7.9E-40 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 SUPERFAMILY SSF52540 3 304 1.38E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 3.4E-160 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 Gene3D G3DSA:3.10.20.30 266 365 1.8E-46 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 Pfam PF01926 50S ribosome-binding GTPase 5 125 1.3E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS19360 729d5a1aa87b60613354bb391db59b60 366 Gene3D G3DSA:1.10.150.300 110 200 1.2E-29 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CXR48_RS03155 4e3aed45b7efe35c430912446334cf95 334 SUPERFAMILY SSF117892 91 226 6.54E-5 T 29-03-2018 IPR001107 Band 7 domain CXR48_RS03155 4e3aed45b7efe35c430912446334cf95 334 Gene3D G3DSA:2.20.70.10 310 322 0.15 T 29-03-2018 CXR48_RS03155 4e3aed45b7efe35c430912446334cf95 334 Gene3D G3DSA:2.20.70.10 323 334 0.3 T 29-03-2018 CXR48_RS03155 4e3aed45b7efe35c430912446334cf95 334 Pfam PF13248 zinc-ribbon domain 311 333 9.0E-8 T 29-03-2018 CXR48_RS03155 4e3aed45b7efe35c430912446334cf95 334 Pfam PF13421 SPFH domain-Band 7 family 27 231 1.9E-44 T 29-03-2018 IPR033880 SPFH domain, YdjI-like CXR48_RS04465 c5a30a60f156e21d4a82c7ab4e779d62 236 Gene3D G3DSA:2.160.10.10 19 236 2.7E-5 T 29-03-2018 CXR48_RS07535 5a7977be1e428291accb337e33bf1b36 306 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 191 304 4.7E-28 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CXR48_RS07535 5a7977be1e428291accb337e33bf1b36 306 Gene3D G3DSA:1.10.1040.10 184 306 5.4E-31 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS07535 5a7977be1e428291accb337e33bf1b36 306 SUPERFAMILY SSF48179 184 304 2.72E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS07535 5a7977be1e428291accb337e33bf1b36 306 SUPERFAMILY SSF51735 15 161 3.35E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07535 5a7977be1e428291accb337e33bf1b36 306 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 15 305 4.1E-72 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CXR48_RS07535 5a7977be1e428291accb337e33bf1b36 306 Gene3D G3DSA:3.40.50.720 13 183 1.2E-28 T 29-03-2018 CXR48_RS07535 5a7977be1e428291accb337e33bf1b36 306 Pfam PF02558 Ketopantoate reductase PanE/ApbA 16 157 1.1E-26 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 454 4.1E-190 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 Gene3D G3DSA:3.90.550.10 2 240 1.5E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 SUPERFAMILY SSF53448 5 253 1.32E-63 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 Pfam PF00483 Nucleotidyl transferase 6 216 6.1E-23 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 Gene3D G3DSA:2.160.10.10 342 455 2.2E-20 T 29-03-2018 CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 Gene3D G3DSA:2.160.10.10 241 341 6.6E-31 T 29-03-2018 CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.579 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 7.3E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 352 5.6E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 300 7.4E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS00315 e4af30ae3b4f1c9239b1aa2364f7c902 456 SUPERFAMILY SSF51161 249 446 3.05E-50 T 29-03-2018 IPR011004 Trimeric LpxA-like CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 Gene3D G3DSA:3.30.1360.60 439 513 1.3E-24 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 Pfam PF00367 phosphotransferase system, EIIB 443 475 1.6E-13 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 552 671 2.9E-46 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 Pfam PF02378 Phosphotransferase system, EIIC 14 354 3.1E-99 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 64 365 1.1E-99 T 29-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 Gene3D G3DSA:2.70.70.10 537 698 2.4E-56 T 29-03-2018 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 453 470 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 551 672 1.6E-48 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 SUPERFAMILY SSF55604 442 512 3.79E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 SUPERFAMILY SSF51261 545 691 1.71E-52 T 29-03-2018 IPR011055 Duplicated hybrid motif CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 613 625 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 413 499 1.3E-26 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS06870 dfceaa85494efb697a5f8a4d9bf03263 698 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 515 1.4E-248 T 29-03-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 CXR48_RS07665 9a65040c2ca11da1ef2d84d790495bf3 92 Pfam PF02325 YGGT family 12 78 1.8E-21 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 Gene3D G3DSA:3.40.366.10 1 131 5.7E-36 T 29-03-2018 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 SUPERFAMILY SSF52151 3 123 1.36E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 SUPERFAMILY SSF52151 189 288 1.36E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 Pfam PF00698 Acyl transferase domain 4 278 3.6E-35 T 29-03-2018 IPR014043 Acyl transferase CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 Gene3D G3DSA:3.30.70.250 132 181 6.5E-17 T 29-03-2018 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 Gene3D G3DSA:3.20.20.70 325 763 1.1E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 326 760 2.1E-173 T 29-03-2018 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 Gene3D G3DSA:3.40.366.10 182 294 6.1E-21 T 29-03-2018 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 281 4.2E-107 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 SUPERFAMILY SSF51395 16 290 8.42E-20 T 29-03-2018 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 SUPERFAMILY SSF51395 327 681 8.42E-20 T 29-03-2018 CXR48_RS07220 74f4dbb78cdf4e7331748de706b0a868 768 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 352 8.9E-38 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CXR48_RS17985 c6087f7eef505e2791391e5e7920a664 112 SUPERFAMILY SSF46785 13 106 9.1E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17985 c6087f7eef505e2791391e5e7920a664 112 Gene3D G3DSA:1.10.10.10 1 98 4.8E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17985 c6087f7eef505e2791391e5e7920a664 112 Pfam PF03551 Transcriptional regulator PadR-like family 15 88 3.1E-27 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CXR48_RS13560 5998c27aba0727539396c0dc0a460800 228 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 227 36.922 T 29-03-2018 IPR022877 Protein of unknown funcion UPF0173 CXR48_RS13560 5998c27aba0727539396c0dc0a460800 228 Gene3D G3DSA:3.60.15.10 1 219 4.7E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS13560 5998c27aba0727539396c0dc0a460800 228 SUPERFAMILY SSF56281 1 208 9.17E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS13560 5998c27aba0727539396c0dc0a460800 228 Pfam PF13483 Beta-lactamase superfamily domain 2 193 6.1E-25 T 29-03-2018 CXR48_RS13560 5998c27aba0727539396c0dc0a460800 228 SMART SM00849 7 193 1.3E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS14730 b92986305ff85fccd0cb7f9c3f2cf078 158 Pfam PF01899 Na+/H+ ion antiporter subunit 8 156 1.4E-43 T 29-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CXR48_RS14730 b92986305ff85fccd0cb7f9c3f2cf078 158 PIRSF PIRSF019239 1 158 2.3E-49 T 29-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CXR48_RS13175 376ed5e9c1d0a276ffb076cf9e0a08ba 259 Gene3D G3DSA:1.10.12.10 225 256 8.9E-15 T 29-03-2018 IPR014748 Crontonase, C-terminal CXR48_RS13175 376ed5e9c1d0a276ffb076cf9e0a08ba 259 SUPERFAMILY SSF52096 5 258 1.28E-82 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS13175 376ed5e9c1d0a276ffb076cf9e0a08ba 259 Gene3D G3DSA:3.90.226.10 2 224 2.4E-70 T 29-03-2018 CXR48_RS13175 376ed5e9c1d0a276ffb076cf9e0a08ba 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CXR48_RS13175 376ed5e9c1d0a276ffb076cf9e0a08ba 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 257 2.6E-62 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CXR48_RS16435 4e926ee30e10398241242e4b955f1dba 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 241 36.683 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CXR48_RS16435 4e926ee30e10398241242e4b955f1dba 245 SUPERFAMILY SSF51366 5 240 3.14E-67 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CXR48_RS16435 4e926ee30e10398241242e4b955f1dba 245 Pfam PF00977 Histidine biosynthesis protein 6 233 1.2E-75 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CXR48_RS16435 4e926ee30e10398241242e4b955f1dba 245 Gene3D G3DSA:3.20.20.70 4 245 3.6E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS16435 4e926ee30e10398241242e4b955f1dba 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 6 237 1.9E-84 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CXR48_RS00470 1159d39dff6d0c56bf607a114a52ccd7 167 Gene3D G3DSA:3.30.70.560 1 157 7.6E-60 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CXR48_RS00470 1159d39dff6d0c56bf607a114a52ccd7 167 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CXR48_RS00470 1159d39dff6d0c56bf607a114a52ccd7 167 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 134 1.3E-49 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CXR48_RS00470 1159d39dff6d0c56bf607a114a52ccd7 167 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 134 7.7E-40 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CXR48_RS00470 1159d39dff6d0c56bf607a114a52ccd7 167 SUPERFAMILY SSF55083 3 140 3.4E-54 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 Gene3D G3DSA:2.40.10.10 127 219 2.6E-7 T 29-03-2018 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 PRINTS PR00839 V8 serine protease family signature 246 262 8.3E-28 T 29-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 PRINTS PR00839 V8 serine protease family signature 213 226 8.3E-28 T 29-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 PRINTS PR00839 V8 serine protease family signature 267 279 8.3E-28 T 29-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 PRINTS PR00839 V8 serine protease family signature 91 108 8.3E-28 T 29-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 PRINTS PR00839 V8 serine protease family signature 121 138 8.3E-28 T 29-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 PRINTS PR00839 V8 serine protease family signature 151 163 8.3E-28 T 29-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 Pfam PF00089 Trypsin 98 291 1.4E-21 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 132 137 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 Gene3D G3DSA:2.40.10.10 85 126 5.7E-5 T 29-03-2018 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 SUPERFAMILY SSF50494 83 297 2.31E-31 T 29-03-2018 IPR009003 Peptidase S1, PA clan CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 ProSitePatterns PS00673 Serine proteases, V8 family, serine active site. 252 262 - T 29-03-2018 IPR000126 Serine proteases, V8 family, serine active site GO:0006508|GO:0008236 CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 ProSitePatterns PS00672 Serine proteases, V8 family, histidine active site. 122 136 - T 29-03-2018 IPR028301 Serine proteases, V8 family, histidine active site CXR48_RS04130 33b782d3dffd686b987e632745fcc5a9 303 Gene3D G3DSA:2.40.10.10 221 303 8.1E-20 T 29-03-2018 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 SMART SM01060 26 419 7.8E-252 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 SUPERFAMILY SSF56634 17 505 1.57E-196 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 Gene3D G3DSA:2.40.180.10 1 381 3.8E-158 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 PRINTS PR00067 Catalase signature 107 125 1.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 PRINTS PR00067 Catalase signature 344 370 1.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 PRINTS PR00067 Catalase signature 312 339 1.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 PRINTS PR00067 Catalase signature 147 165 1.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 PRINTS PR00067 Catalase signature 128 145 1.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 PRINTS PR00067 Catalase signature 39 62 1.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 Pfam PF00199 Catalase 26 415 1.2E-172 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 ProSitePatterns PS00438 Catalase proximal active site signature. 62 78 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 Pfam PF06628 Catalase-related immune-responsive 441 503 6.4E-20 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 357 365 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS18355 e4d821e5bf99472febe34307626e9bed 537 PIRSF PIRSF038928 13 509 6.3E-180 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS01955 527c84eef1723cf2cda9d2b7b9df74d6 31 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 8 28 4.6E-13 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS01955 527c84eef1723cf2cda9d2b7b9df74d6 31 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 8 28 2.8E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS02460 870de02ae8ab0e129b6e8ea5d081a6e6 160 Gene3D G3DSA:3.30.565.10 3 155 8.8E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02460 870de02ae8ab0e129b6e8ea5d081a6e6 160 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 1 159 1.4E-83 T 29-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CXR48_RS02460 870de02ae8ab0e129b6e8ea5d081a6e6 160 SUPERFAMILY SSF55874 31 137 2.62E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02460 870de02ae8ab0e129b6e8ea5d081a6e6 160 Pfam PF13581 Histidine kinase-like ATPase domain 12 141 6.3E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02460 870de02ae8ab0e129b6e8ea5d081a6e6 160 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 2 156 39.437 T 29-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CXR48_RS13775 8c79aaee2929704b6a7698769f329859 214 Gene3D G3DSA:3.10.580.10 1 150 2.3E-25 T 29-03-2018 CXR48_RS13775 8c79aaee2929704b6a7698769f329859 214 Pfam PF00571 CBS domain 74 126 5.1E-8 T 29-03-2018 IPR000644 CBS domain CXR48_RS13775 8c79aaee2929704b6a7698769f329859 214 Pfam PF00571 CBS domain 4 55 1.4E-12 T 29-03-2018 IPR000644 CBS domain CXR48_RS13775 8c79aaee2929704b6a7698769f329859 214 SUPERFAMILY SSF54631 1 129 2.81E-28 T 29-03-2018 CXR48_RS13775 8c79aaee2929704b6a7698769f329859 214 SMART SM00116 81 128 5.1E-9 T 29-03-2018 IPR000644 CBS domain CXR48_RS13775 8c79aaee2929704b6a7698769f329859 214 SMART SM00116 10 58 3.3E-10 T 29-03-2018 IPR000644 CBS domain CXR48_RS19355 8467545102aeffd0c4516d52d09a8176 95 Pfam PF01250 Ribosomal protein S6 3 92 6.4E-29 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19355 8467545102aeffd0c4516d52d09a8176 95 Gene3D G3DSA:3.30.70.60 1 95 2.8E-30 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CXR48_RS19355 8467545102aeffd0c4516d52d09a8176 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.1E-36 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19355 8467545102aeffd0c4516d52d09a8176 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 23.585 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CXR48_RS19355 8467545102aeffd0c4516d52d09a8176 95 SUPERFAMILY SSF54995 1 95 7.33E-34 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19355 8467545102aeffd0c4516d52d09a8176 95 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 29-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 CXR48_RS02305 25fc98df5e69b3182362065e141d6264 119 Pfam PF16291 Domain of unknown function (DUF4937 2 92 1.0E-30 T 29-03-2018 IPR032555 Domain of unknown function DUF4937 CXR48_RS02305 25fc98df5e69b3182362065e141d6264 119 SUPERFAMILY SSF54909 1 93 2.41E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS02305 25fc98df5e69b3182362065e141d6264 119 Gene3D G3DSA:3.30.70.100 1 95 1.5E-4 T 29-03-2018 CXR48_RS02455 b12a7a657d137fe51bb225cba7b74851 109 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 105 2.9E-31 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CXR48_RS02455 b12a7a657d137fe51bb225cba7b74851 109 Gene3D G3DSA:3.30.750.24 7 108 1.1E-13 T 29-03-2018 IPR002645 STAS domain CXR48_RS02455 b12a7a657d137fe51bb225cba7b74851 109 Pfam PF01740 STAS domain 6 99 1.2E-14 T 29-03-2018 IPR002645 STAS domain CXR48_RS02455 b12a7a657d137fe51bb225cba7b74851 109 SUPERFAMILY SSF52091 14 101 3.34E-21 T 29-03-2018 IPR002645 STAS domain CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 SUPERFAMILY SSF52540 211 390 1.83E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 SUPERFAMILY SSF50447 389 472 3.53E-26 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Gene3D G3DSA:3.30.56.50 143 184 4.9E-11 T 29-03-2018 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Gene3D G3DSA:3.30.56.50 4 46 3.7E-10 T 29-03-2018 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 133 715 1.7E-290 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Pfam PF11987 Translation-initiation factor 2 503 607 3.1E-38 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 ProSitePatterns PS01176 Initiation factor 2 signature. 668 690 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Gene3D G3DSA:2.40.30.10 618 716 1.6E-31 T 29-03-2018 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Gene3D G3DSA:3.40.50.300 190 388 5.5E-41 T 29-03-2018 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Pfam PF00009 Elongation factor Tu GTP binding domain 222 377 1.8E-35 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Gene3D G3DSA:2.40.30.10 389 482 1.3E-14 T 29-03-2018 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Gene3D G3DSA:3.40.50.10050 515 596 1.6E-28 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 SUPERFAMILY SSF52156 495 624 1.31E-40 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 2.7E-12 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 143 191 4.7E-15 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 SUPERFAMILY SSF50447 618 715 3.33E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 715 17.52 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CXR48_RS08295 4522848f9717717b2667f7ec2aee79c7 716 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 220 376 5.5E-44 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS02535 27f7cb0050a7c1672bb2cb233a53eddd 267 Pfam PF12146 Serine aminopeptidase, S33 14 244 2.2E-14 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CXR48_RS02535 27f7cb0050a7c1672bb2cb233a53eddd 267 Gene3D G3DSA:3.40.50.1820 1 263 4.0E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS02535 27f7cb0050a7c1672bb2cb233a53eddd 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 3.0E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS02535 27f7cb0050a7c1672bb2cb233a53eddd 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 3.0E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS02535 27f7cb0050a7c1672bb2cb233a53eddd 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 3.0E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS02535 27f7cb0050a7c1672bb2cb233a53eddd 267 SUPERFAMILY SSF53474 3 257 3.62E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 4.9E-73 T 29-03-2018 CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 Gene3D G3DSA:3.40.50.720 45 246 1.3E-73 T 29-03-2018 CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 SUPERFAMILY SSF51735 4 246 2.84E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 9.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 9.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 9.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 4.4E-6 T 29-03-2018 CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 Gene3D G3DSA:3.40.50.10090 1 44 1.7E-9 T 29-03-2018 CXR48_RS07930 c83efacb7b53c61cb2d6119525246815 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 3.8E-111 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CXR48_RS03940 14a8a52a9f2b3785675182fb30d0203b 287 SUPERFAMILY SSF48150 107 285 7.15E-39 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CXR48_RS03940 14a8a52a9f2b3785675182fb30d0203b 287 SMART SM00478 127 286 1.5E-26 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CXR48_RS03940 14a8a52a9f2b3785675182fb30d0203b 287 Gene3D G3DSA:1.10.340.30 93 251 3.4E-27 T 29-03-2018 CXR48_RS03940 14a8a52a9f2b3785675182fb30d0203b 287 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 124 271 3.4E-18 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CXR48_RS03940 14a8a52a9f2b3785675182fb30d0203b 287 Gene3D G3DSA:1.10.1670.10 252 287 3.1E-11 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 205 1.9E-42 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 Pfam PF00378 Enoyl-CoA hydratase/isomerase 490 623 1.6E-12 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 Gene3D G3DSA:1.10.1040.10 365 459 1.9E-12 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 SUPERFAMILY SSF48179 357 449 3.06E-18 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 Gene3D G3DSA:1.10.1040.10 206 312 1.1E-16 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 SUPERFAMILY SSF48179 206 325 5.1E-21 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 SUPERFAMILY SSF51735 4 206 1.65E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 Gene3D G3DSA:3.90.226.10 474 788 4.8E-39 T 29-03-2018 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 208 306 1.2E-11 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 371 413 1.6E-4 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 SUPERFAMILY SSF52096 482 786 8.37E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS15350 fbf2cbd037929ead5080bb04fb947391 789 Gene3D G3DSA:3.40.50.720 3 205 3.3E-40 T 29-03-2018 CXR48_RS18685 1230f40d6e5a5c2995f82f62fe2096f6 290 PIRSF PIRSF001359 1 284 3.7E-119 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS18685 1230f40d6e5a5c2995f82f62fe2096f6 290 SUPERFAMILY SSF51569 1 284 4.98E-95 T 29-03-2018 CXR48_RS18685 1230f40d6e5a5c2995f82f62fe2096f6 290 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 284 2.6E-126 T 29-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CXR48_RS18685 1230f40d6e5a5c2995f82f62fe2096f6 290 Gene3D G3DSA:3.20.20.70 1 286 1.5E-97 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS18685 1230f40d6e5a5c2995f82f62fe2096f6 290 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 283 1.5E-95 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS18685 1230f40d6e5a5c2995f82f62fe2096f6 290 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS18685 1230f40d6e5a5c2995f82f62fe2096f6 290 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS18685 1230f40d6e5a5c2995f82f62fe2096f6 290 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 284 3.5E-112 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS07870 004485d462a63aa8f86f0da01428c766 217 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CXR48_RS07870 004485d462a63aa8f86f0da01428c766 217 SUPERFAMILY SSF51366 1 214 5.72E-77 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CXR48_RS07870 004485d462a63aa8f86f0da01428c766 217 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 214 9.5E-95 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CXR48_RS07870 004485d462a63aa8f86f0da01428c766 217 Gene3D G3DSA:3.20.20.70 1 216 4.5E-90 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS07870 004485d462a63aa8f86f0da01428c766 217 PIRSF PIRSF001461 1 217 5.2E-100 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CXR48_RS07870 004485d462a63aa8f86f0da01428c766 217 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 201 2.3E-92 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CXR48_RS07870 004485d462a63aa8f86f0da01428c766 217 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CXR48_RS05915 10b4f7681fce3f8be152833d1fccc551 93 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 77 3.2E-10 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CXR48_RS05915 10b4f7681fce3f8be152833d1fccc551 93 Gene3D G3DSA:3.30.70.100 1 92 3.1E-14 T 29-03-2018 CXR48_RS05915 10b4f7681fce3f8be152833d1fccc551 93 SUPERFAMILY SSF54909 1 81 2.82E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS07820 676e72f51068612a4aebbe17e72ee434 67 Pfam PF01192 RNA polymerase Rpb6 9 61 1.0E-11 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CXR48_RS07820 676e72f51068612a4aebbe17e72ee434 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 2.8E-28 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS07820 676e72f51068612a4aebbe17e72ee434 67 SUPERFAMILY SSF63562 1 65 1.57E-20 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CXR48_RS07820 676e72f51068612a4aebbe17e72ee434 67 Gene3D G3DSA:3.90.940.10 1 67 1.2E-19 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CXR48_RS07820 676e72f51068612a4aebbe17e72ee434 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 13.772 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS07820 676e72f51068612a4aebbe17e72ee434 67 SMART SM01409 8 61 2.0E-11 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CXR48_RS03585 b742ef49e5b0d5ff8802792f0ccaf6bb 303 SUPERFAMILY SSF53448 5 274 6.19E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS03585 b742ef49e5b0d5ff8802792f0ccaf6bb 303 Pfam PF03407 Nucleotide-diphospho-sugar transferase 33 198 1.1E-5 T 29-03-2018 IPR005069 Nucleotide-diphospho-sugar transferase CXR48_RS03585 b742ef49e5b0d5ff8802792f0ccaf6bb 303 Gene3D G3DSA:3.90.550.10 3 267 2.3E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 SUPERFAMILY SSF52343 254 389 1.83E-33 T 29-03-2018 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 SUPERFAMILY SSF63380 152 254 1.04E-25 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 Pfam PF00042 Globin 7 102 2.0E-11 T 29-03-2018 IPR000971 Globin GO:0020037 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 Pfam PF00175 Oxidoreductase NAD-binding domain 264 371 2.8E-18 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 357 365 9.9E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 185 197 9.9E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 263 282 9.9E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 247 256 9.9E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 288 297 9.9E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 Hamap MF_01252 Flavohemoprotein [hmp]. 1 395 53.192 T 29-03-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 SUPERFAMILY SSF46458 2 143 1.83E-41 T 29-03-2018 IPR009050 Globin-like CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 Gene3D G3DSA:3.40.50.80 245 386 3.7E-28 T 29-03-2018 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 Pfam PF00970 Oxidoreductase FAD-binding domain 157 252 2.5E-9 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 Gene3D G3DSA:1.10.490.10 1 160 1.1E-41 T 29-03-2018 CXR48_RS13710 80f785738a6f492d53ebc912801b7b4f 396 Gene3D G3DSA:2.40.30.10 161 244 7.5E-24 T 29-03-2018 CXR48_RS03280 e7a6281db2d6f8286c93945138531de7 241 Pfam PF01259 SAICAR synthetase 9 233 1.9E-69 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03280 e7a6281db2d6f8286c93945138531de7 241 Gene3D G3DSA:3.30.200.20 3 95 5.2E-29 T 29-03-2018 CXR48_RS03280 e7a6281db2d6f8286c93945138531de7 241 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 6 237 33.87 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03280 e7a6281db2d6f8286c93945138531de7 241 SUPERFAMILY SSF56104 3 238 1.54E-83 T 29-03-2018 CXR48_RS03280 e7a6281db2d6f8286c93945138531de7 241 Gene3D G3DSA:3.30.470.20 96 223 3.9E-49 T 29-03-2018 CXR48_RS03280 e7a6281db2d6f8286c93945138531de7 241 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 6 240 4.1E-87 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CXR48_RS03280 e7a6281db2d6f8286c93945138531de7 241 ProSitePatterns PS01057 SAICAR synthetase signature 1. 88 102 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03280 e7a6281db2d6f8286c93945138531de7 241 ProSitePatterns PS01058 SAICAR synthetase signature 2. 175 183 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 533 663 1.1E-46 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 Gene3D G3DSA:2.40.50.140 555 663 1.1E-27 T 29-03-2018 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 Gene3D G3DSA:3.40.50.620 5 358 3.6E-105 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 Pfam PF01588 Putative tRNA binding domain 569 660 1.3E-26 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 6.1E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 6.1E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 362 373 6.1E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 270 285 6.1E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 6.1E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 237 248 6.1E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 522 52.2 T 29-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 Pfam PF08264 Anticodon-binding domain of tRNA 398 547 2.4E-10 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 Pfam PF09334 tRNA synthetases class I (M) 8 374 9.2E-122 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 Gene3D G3DSA:1.10.730.10 359 525 4.5E-42 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 SUPERFAMILY SSF50249 563 662 9.3E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 524 8.8E-193 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 SUPERFAMILY SSF47323 364 576 7.29E-49 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS00255 7a40536203889ae20efdc933e4f497ea 663 SUPERFAMILY SSF52374 4 361 6.97E-118 T 29-03-2018 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 SUPERFAMILY SSF63380 672 895 4.86E-63 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PIRSF PIRSF000209 1 1060 0.0 T 29-03-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 Pfam PF00067 Cytochrome P450 12 444 3.3E-83 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 Pfam PF00175 Oxidoreductase NAD-binding domain 912 1020 1.4E-17 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 Gene3D G3DSA:1.10.630.10 5 463 2.0E-112 T 29-03-2018 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 SUPERFAMILY SSF48264 6 453 3.67E-110 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 Gene3D G3DSA:3.40.50.80 897 1056 4.5E-36 T 29-03-2018 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 Gene3D G3DSA:2.40.30.10 665 892 2.0E-49 T 29-03-2018 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 Pfam PF00258 Flavodoxin 494 626 1.5E-27 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 Pfam PF00667 FAD binding domain 673 879 7.7E-36 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 Gene3D G3DSA:3.40.50.360 464 652 8.7E-43 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 952 963 6.4E-33 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 874 883 6.4E-33 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 705 715 6.4E-33 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 940 949 6.4E-33 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 983 999 6.4E-33 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1006 1014 6.4E-33 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 911 930 6.4E-33 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 839 846 6.4E-33 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 SUPERFAMILY SSF52343 900 1057 9.17E-46 T 29-03-2018 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00369 Flavodoxin signature 571 581 5.5E-12 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00369 Flavodoxin signature 493 506 5.5E-12 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 PRINTS PR00369 Flavodoxin signature 596 615 5.5E-12 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS03565 65a0e99f01e6c4110c49548a59a13cfc 1060 SUPERFAMILY SSF52218 488 643 2.51E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS14205 25341f010a548f5836e5cba2ab7ae9bd 189 Gene3D G3DSA:3.40.1050.10 1 188 9.9E-34 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CXR48_RS14205 25341f010a548f5836e5cba2ab7ae9bd 189 Pfam PF00484 Carbonic anhydrase 34 178 2.3E-18 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CXR48_RS14205 25341f010a548f5836e5cba2ab7ae9bd 189 SMART SM00947 26 182 5.5E-36 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CXR48_RS14205 25341f010a548f5836e5cba2ab7ae9bd 189 SUPERFAMILY SSF53056 1 181 8.63E-43 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CXR48_RS07140 e619d9928602e42241f709f96768ad22 44 Pfam PF17447 Uncharacterized protein YkpC 29 42 4.5E-6 T 29-03-2018 IPR035379 Uncharacterized protein YkpC CXR48_RS07140 e619d9928602e42241f709f96768ad22 44 ProDom PD049302 YKPC PRECURSOR SIGNAL 1 42 6.0E-6 T 29-03-2018 IPR035379 Uncharacterized protein YkpC CXR48_RS00600 0c52f8b2fdc329e22cd2e4246311cb5d 232 SUPERFAMILY SSF53448 3 224 9.97E-63 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS00600 0c52f8b2fdc329e22cd2e4246311cb5d 232 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 223 43.386 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CXR48_RS00600 0c52f8b2fdc329e22cd2e4246311cb5d 232 Gene3D G3DSA:3.90.550.10 1 230 2.8E-52 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS00600 0c52f8b2fdc329e22cd2e4246311cb5d 232 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 100 107 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CXR48_RS00600 0c52f8b2fdc329e22cd2e4246311cb5d 232 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 224 2.7E-84 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CXR48_RS00600 0c52f8b2fdc329e22cd2e4246311cb5d 232 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 223 3.3E-80 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 8.0E-9 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 Pfam PF01165 Ribosomal protein S21 5 57 2.5E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.664 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.1E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.1E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.1E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.1E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 Gene3D G3DSA:1.20.5.1150 16 52 1.7E-18 T 29-03-2018 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 2.4E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12205 14b9659fd5d60c2bb9b0636536514cb6 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 29-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 Gene3D G3DSA:3.30.420.40 158 193 0.0012 T 29-03-2018 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 SUPERFAMILY SSF53067 147 329 8.26E-51 T 29-03-2018 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 333 1.6E-162 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 1.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 297 323 1.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 1.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 1.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 1.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 Gene3D G3DSA:3.90.640.10 194 248 2.8E-30 T 29-03-2018 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 Gene3D G3DSA:3.30.420.40 4 157 7.6E-36 T 29-03-2018 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 Gene3D G3DSA:3.30.420.40 249 314 7.1E-10 T 29-03-2018 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 SUPERFAMILY SSF53067 8 144 1.3E-37 T 29-03-2018 CXR48_RS12910 a7b45dacd290530bc50407e453323274 337 Pfam PF06723 MreB/Mbl protein 7 331 4.9E-151 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS14670 6e77d6b769ec49751fe8d1c80d6d526a 185 ProDom PD108804 YUFK TRANSMEMBRANE MEMBRANE PRECURSOR SIGNAL 1 185 1.0E-63 T 29-03-2018 IPR035289 Protein of unknown function DUF5366 CXR48_RS14670 6e77d6b769ec49751fe8d1c80d6d526a 185 Pfam PF17328 Family of unknown function (DUF5366) 29 184 2.9E-61 T 29-03-2018 IPR035289 Protein of unknown function DUF5366 CXR48_RS00125 1afa69cb3415371f2368924169009999 160 Gene3D G3DSA:3.40.140.10 1 158 8.6E-51 T 29-03-2018 CXR48_RS00125 1afa69cb3415371f2368924169009999 160 SUPERFAMILY SSF53927 2 152 1.67E-53 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CXR48_RS00125 1afa69cb3415371f2368924169009999 160 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CXR48_RS00125 1afa69cb3415371f2368924169009999 160 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 148 46.86 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CXR48_RS00125 1afa69cb3415371f2368924169009999 160 Pfam PF14437 MafB19-like deaminase 1 148 3.2E-41 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 318 3.6E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 Pfam PF00672 HAMP domain 192 241 3.6E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 SUPERFAMILY SSF158472 192 242 3.79E-7 T 29-03-2018 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 3.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 471 3.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 3.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 3.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 SUPERFAMILY SSF55874 310 471 2.62E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 Gene3D G3DSA:1.10.287.130 236 316 4.4E-17 T 29-03-2018 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 SUPERFAMILY SSF47384 235 318 1.43E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 SMART SM00387 362 472 1.5E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 Gene3D G3DSA:3.30.565.10 333 472 3.7E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 SMART SM00388 253 320 2.1E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 471 8.4E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18995 e669ccc7c797eed80f471813818d76f8 472 SMART SM00304 192 245 1.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS01545 cc4eb682b90d3b750528c1d8f4711383 198 Gene3D G3DSA:2.60.60.30 18 195 2.3E-53 T 29-03-2018 CXR48_RS01545 cc4eb682b90d3b750528c1d8f4711383 198 Pfam PF02342 TerD domain 1 197 5.8E-74 T 29-03-2018 IPR003325 TerD domain GO:0006950 CXR48_RS16055 852b54a5e968410642b2ab8dd2724154 335 SUPERFAMILY SSF51679 11 331 1.13E-87 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS16055 852b54a5e968410642b2ab8dd2724154 335 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 11 331 2.0E-137 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CXR48_RS16055 852b54a5e968410642b2ab8dd2724154 335 Pfam PF00296 Luciferase-like monooxygenase 24 303 9.1E-40 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS16055 852b54a5e968410642b2ab8dd2724154 335 Gene3D G3DSA:3.20.20.30 14 334 7.3E-77 T 29-03-2018 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 Pfam PF00128 Alpha amylase, catalytic domain 28 372 2.5E-114 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 Gene3D G3DSA:3.20.20.80 6 117 1.9E-34 T 29-03-2018 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 SUPERFAMILY SSF51445 3 472 8.86E-151 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 Pfam PF16657 Maltogenic Amylase, C-terminal domain 475 548 2.5E-6 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 Gene3D G3DSA:2.60.40.1180 476 552 1.4E-16 T 29-03-2018 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 PRINTS PR00110 Alpha-amylase signature 92 103 1.0E-5 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 PRINTS PR00110 Alpha-amylase signature 316 328 1.0E-5 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 PRINTS PR00110 Alpha-amylase signature 193 204 1.0E-5 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 SMART SM00642 13 414 1.4E-158 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 Gene3D G3DSA:3.20.20.470 168 339 5.4E-34 T 29-03-2018 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 SUPERFAMILY SSF51011 475 551 4.93E-14 T 29-03-2018 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 Gene3D G3DSA:3.90.400.10 118 167 1.7E-33 T 29-03-2018 CXR48_RS14530 d1338ae87b3710b101213c41ca364a55 552 Gene3D G3DSA:3.20.20.80 340 475 1.5E-23 T 29-03-2018 CXR48_RS02780 0da4c9964302bb330ce429b3a3d16af1 378 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 139 4.6E-29 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS02780 0da4c9964302bb330ce429b3a3d16af1 378 SUPERFAMILY SSF51735 157 340 1.16E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS02780 0da4c9964302bb330ce429b3a3d16af1 378 Gene3D G3DSA:3.40.50.720 178 331 5.2E-21 T 29-03-2018 CXR48_RS02780 0da4c9964302bb330ce429b3a3d16af1 378 Gene3D G3DSA:3.90.180.10 1 177 5.2E-47 T 29-03-2018 CXR48_RS02780 0da4c9964302bb330ce429b3a3d16af1 378 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CXR48_RS02780 0da4c9964302bb330ce429b3a3d16af1 378 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 1.3E-11 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CXR48_RS02780 0da4c9964302bb330ce429b3a3d16af1 378 Pfam PF00107 Zinc-binding dehydrogenase 189 257 1.2E-8 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS02780 0da4c9964302bb330ce429b3a3d16af1 378 SUPERFAMILY SSF50129 1 188 3.2E-59 T 29-03-2018 IPR011032 GroES-like CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 Pfam PF00271 Helicase conserved C-terminal domain 452 572 5.2E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 SMART SM00490 488 573 1.1E-19 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 Pfam PF00270 DEAD/DEAH box helicase 261 415 6.3E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 Pfam PF17191 RecG wedge domain 11 165 6.0E-17 T 29-03-2018 IPR033454 RecG, wedge domain CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 SUPERFAMILY SSF52540 173 436 5.79E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 Gene3D G3DSA:1.10.150.20 4 54 1.1E-4 T 29-03-2018 CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 Gene3D G3DSA:2.40.50.140 55 140 1.8E-9 T 29-03-2018 CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 SUPERFAMILY SSF52540 369 629 9.58E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 Gene3D G3DSA:3.40.50.300 441 613 3.0E-33 T 29-03-2018 CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 Gene3D G3DSA:3.40.50.300 238 440 5.5E-37 T 29-03-2018 CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 648 1.0E-257 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 SMART SM00487 253 442 5.3E-33 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS07910 ae46fe11000a09f9fc1202b40506d16b 682 SUPERFAMILY SSF50249 5 167 7.02E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Gene3D G3DSA:2.40.10.10 107 235 9.0E-30 T 29-03-2018 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Pfam PF13180 PDZ domain 343 442 5.1E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Gene3D G3DSA:2.30.42.10 346 450 3.2E-23 T 29-03-2018 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 SUPERFAMILY SSF50156 327 441 9.6E-19 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Pfam PF13365 Trypsin-like peptidase domain 161 305 1.6E-29 T 29-03-2018 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 SMART SM00228 343 433 1.8E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Gene3D G3DSA:2.40.10.10 236 345 6.2E-35 T 29-03-2018 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 SUPERFAMILY SSF50494 109 340 9.09E-56 T 29-03-2018 IPR009003 Peptidase S1, PA clan CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 173 185 7.2E-39 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 390 402 7.2E-39 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 276 293 7.2E-39 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 235 259 7.2E-39 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 298 315 7.2E-39 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS06415 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 194 214 7.2E-39 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 Pfam PF01293 Phosphoenolpyruvate carboxykinase 18 481 1.1E-224 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 250 265 - T 29-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 Gene3D G3DSA:3.90.228.20 292 525 4.6E-94 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 Gene3D G3DSA:3.90.228.20 213 291 6.9E-30 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 Gene3D G3DSA:3.40.449.10 19 211 4.8E-79 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 PIRSF PIRSF006294 3 526 2.5E-241 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 SUPERFAMILY SSF68923 11 212 6.1E-80 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 SUPERFAMILY SSF53795 213 518 7.1E-135 T 29-03-2018 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 527 55.725 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CXR48_RS14140 26c680a41801e8fdcc5a423ddb515c1c 527 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 2 526 1.6E-265 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CXR48_RS09305 9348e38bcee3aa8b44ce23d5a8a62814 100 Gene3D G3DSA:1.10.10.10 8 87 2.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09305 9348e38bcee3aa8b44ce23d5a8a62814 100 Pfam PF12840 Helix-turn-helix domain 5 77 8.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09305 9348e38bcee3aa8b44ce23d5a8a62814 100 SMART SM00418 5 98 6.8E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS09305 9348e38bcee3aa8b44ce23d5a8a62814 100 SUPERFAMILY SSF46785 4 97 1.15E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06230 17360c680eef868a633fa43e395938ea 265 Gene3D G3DSA:1.10.10.60 2 165 0.0019 T 29-03-2018 CXR48_RS06230 17360c680eef868a633fa43e395938ea 265 Pfam PF10668 Phage terminase small subunit 4 51 9.3E-7 T 29-03-2018 IPR018925 Phage terminase small subunit CXR48_RS06230 17360c680eef868a633fa43e395938ea 265 Pfam PF03592 Terminase small subunit 67 235 2.1E-42 T 29-03-2018 IPR005335 Terminase small subunit GO:0006323 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 SUPERFAMILY SSF55681 9 237 8.3E-101 T 29-03-2018 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 SUPERFAMILY SSF55681 404 475 8.3E-101 T 29-03-2018 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 Gene3D G3DSA:3.30.930.10 11 457 2.7E-95 T 29-03-2018 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 Gene3D G3DSA:3.40.50.800 458 564 2.0E-29 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 SUPERFAMILY SSF55826 218 386 4.84E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 564 41.246 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 Pfam PF04073 Aminoacyl-tRNA editing domain 257 371 3.8E-31 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 SUPERFAMILY SSF52954 460 563 2.45E-28 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 7.7E-17 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 7.7E-17 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 7.7E-17 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 7.7E-17 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 Pfam PF03129 Anticodon binding domain 474 563 1.3E-19 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 563 7.2E-258 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 PIRSF PIRSF001535 1 564 6.5E-261 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CXR48_RS08265 aa78ef902df3bebde9e2662a945f1440 564 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 456 6.7E-54 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS14015 6ce65f4f9e999d8527c89148c715a9b3 236 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 13 229 6.0E-65 T 29-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CXR48_RS14015 6ce65f4f9e999d8527c89148c715a9b3 236 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 16 226 5.2E-54 T 29-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CXR48_RS04435 92c17f142ff794cbb974ac0495ccc33a 207 SUPERFAMILY SSF56037 84 201 8.11E-9 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CXR48_RS04435 92c17f142ff794cbb974ac0495ccc33a 207 Gene3D G3DSA:3.50.40.10 77 166 1.6E-4 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 Gene3D G3DSA:1.10.10.10 2 79 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 Gene3D G3DSA:3.90.1150.10 386 480 6.7E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 3.7E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 3.7E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 SUPERFAMILY SSF46785 8 86 2.01E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 SMART SM00345 18 77 2.8E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 3.6E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 Gene3D G3DSA:3.40.640.10 135 385 2.6E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 Pfam PF00155 Aminotransferase class I and II 120 467 8.7E-31 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS19250 fcc5b976fe55c1b8064f3e0ebff4a515 482 SUPERFAMILY SSF53383 102 478 2.42E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS11010 c92e3bdac41544702bf97994f10dff04 251 Hamap MF_01805 Segregation and condensation protein A [scpA]. 4 246 28.097 T 29-03-2018 IPR003768 Segregation and condensation protein A CXR48_RS11010 c92e3bdac41544702bf97994f10dff04 251 Gene3D G3DSA:1.10.10.580 180 244 4.6E-17 T 29-03-2018 CXR48_RS11010 c92e3bdac41544702bf97994f10dff04 251 Pfam PF02616 Segregation and condensation protein ScpA 21 244 6.5E-79 T 29-03-2018 IPR003768 Segregation and condensation protein A CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 289 1.1E-102 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 Gene3D G3DSA:3.40.50.1370 1 151 4.6E-57 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 140 2.1E-42 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 291 38.843 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 207 216 2.1E-34 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 2.1E-34 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 2.1E-34 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 270 284 2.1E-34 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 2.1E-34 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 246 251 2.1E-34 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 285 1.0E-22 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 Gene3D G3DSA:3.40.50.1370 152 304 6.5E-43 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 242 251 3.8E-22 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 3.8E-22 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 3.8E-22 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 254 277 3.8E-22 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS07715 54c7f01f5caa0e56cc3667065e3b68ed 304 SUPERFAMILY SSF53671 1 289 4.19E-91 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 PRINTS PR00758 Arsenical pump membrane protein signature 180 203 1.6E-113 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 PRINTS PR00758 Arsenical pump membrane protein signature 147 171 1.6E-113 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 PRINTS PR00758 Arsenical pump membrane protein signature 281 305 1.6E-113 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 PRINTS PR00758 Arsenical pump membrane protein signature 400 424 1.6E-113 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 PRINTS PR00758 Arsenical pump membrane protein signature 104 128 1.6E-113 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 PRINTS PR00758 Arsenical pump membrane protein signature 220 245 1.6E-113 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 PRINTS PR00758 Arsenical pump membrane protein signature 367 392 1.6E-113 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 PRINTS PR00758 Arsenical pump membrane protein signature 326 348 1.6E-113 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 6 429 1.4E-218 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS18315 0eb37a2e801afce63ddd9d3ec4eb2dba 432 Pfam PF02040 Arsenical pump membrane protein 7 428 7.2E-233 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS13660 c9cba12e011872df69cba62b9ec9b353 270 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 265 5.3E-85 T 29-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 CXR48_RS13660 c9cba12e011872df69cba62b9ec9b353 270 Gene3D G3DSA:3.20.20.140 2 270 1.6E-35 T 29-03-2018 CXR48_RS13660 c9cba12e011872df69cba62b9ec9b353 270 Pfam PF13263 PHP-associated 236 261 1.7E-5 T 29-03-2018 CXR48_RS13660 c9cba12e011872df69cba62b9ec9b353 270 SUPERFAMILY SSF89550 4 263 5.76E-37 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CXR48_RS13660 c9cba12e011872df69cba62b9ec9b353 270 Pfam PF02811 PHP domain 5 217 2.5E-14 T 29-03-2018 IPR004013 PHP domain GO:0003824 CXR48_RS05050 44d82763959922e186b4e13e52ff8bdc 353 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 10 342 7.7E-126 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CXR48_RS05050 44d82763959922e186b4e13e52ff8bdc 353 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 8 343 6.5E-121 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CXR48_RS05050 44d82763959922e186b4e13e52ff8bdc 353 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 344 46.444 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CXR48_RS05050 44d82763959922e186b4e13e52ff8bdc 353 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CXR48_RS05050 44d82763959922e186b4e13e52ff8bdc 353 Gene3D G3DSA:3.20.20.210 1 346 9.3E-95 T 29-03-2018 CXR48_RS05050 44d82763959922e186b4e13e52ff8bdc 353 SUPERFAMILY SSF51726 7 345 1.96E-101 T 29-03-2018 CXR48_RS05050 44d82763959922e186b4e13e52ff8bdc 353 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 SMART SM00028 263 296 0.38 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 SMART SM00028 183 216 12.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 SMART SM00028 142 175 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 SMART SM00028 223 256 6.0E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 Pfam PF13424 Tetratricopeptide repeat 223 294 2.6E-9 T 29-03-2018 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 SUPERFAMILY SSF48452 121 326 2.91E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 Gene3D G3DSA:1.25.40.10 156 228 1.6E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 Gene3D G3DSA:1.25.40.10 2 154 1.9E-32 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 Gene3D G3DSA:1.25.40.10 229 273 2.3E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS01945 6137ce392691fc1b5fb3dd744b354ac1 382 Gene3D G3DSA:1.10.150.200 274 320 0.0059 T 29-03-2018 CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 SMART SM00065 238 373 2.0E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 579 3.8E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 Gene3D G3DSA:3.30.450.40 212 387 1.6E-7 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 Gene3D G3DSA:3.30.565.10 388 579 1.9E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 SUPERFAMILY SSF55874 433 578 5.63E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 Pfam PF13492 GAF domain 259 364 2.4E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 Pfam PF06580 Histidine kinase 378 455 9.2E-24 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 SMART SM00387 468 580 6.7E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 Pfam PF07694 5TMR of 5TMR-LYT 25 207 6.8E-60 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CXR48_RS13360 a15f0d4c502539c35d0560505a298780 593 SUPERFAMILY SSF55781 244 364 8.97E-8 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 SUPERFAMILY SSF103473 1 383 2.09E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 PRINTS PR01035 Tetracycline resistance protein signature 69 93 6.7E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 PRINTS PR01035 Tetracycline resistance protein signature 331 354 6.7E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 PRINTS PR01035 Tetracycline resistance protein signature 38 57 6.7E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 PRINTS PR01035 Tetracycline resistance protein signature 126 148 6.7E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 PRINTS PR01035 Tetracycline resistance protein signature 270 291 6.7E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 PRINTS PR01035 Tetracycline resistance protein signature 96 117 6.7E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 Gene3D G3DSA:1.20.1250.20 1 191 1.1E-31 T 29-03-2018 CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 Pfam PF07690 Major Facilitator Superfamily 1 255 1.2E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS14655 f413af93f07fb18415558416eb72f487 392 Gene3D G3DSA:1.20.1250.20 193 390 3.2E-26 T 29-03-2018 CXR48_RS00980 6f991a038ebd54df787d68bb52eed62c 316 Gene3D G3DSA:3.40.190.80 150 301 2.5E-23 T 29-03-2018 CXR48_RS00980 6f991a038ebd54df787d68bb52eed62c 316 Pfam PF00459 Inositol monophosphatase family 32 300 3.9E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS00980 6f991a038ebd54df787d68bb52eed62c 316 Gene3D G3DSA:3.30.540.10 12 115 1.1E-12 T 29-03-2018 CXR48_RS00980 6f991a038ebd54df787d68bb52eed62c 316 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 1.1E-8 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS00980 6f991a038ebd54df787d68bb52eed62c 316 PRINTS PR00377 Inositol monophosphatase superfamily signature 36 56 1.1E-8 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS00980 6f991a038ebd54df787d68bb52eed62c 316 PRINTS PR00377 Inositol monophosphatase superfamily signature 241 265 1.1E-8 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS00980 6f991a038ebd54df787d68bb52eed62c 316 SUPERFAMILY SSF56655 33 304 4.58E-26 T 29-03-2018 CXR48_RS00975 647070966b3d5f9ae25fd5bbf68b1f95 422 Pfam PF00202 Aminotransferase class-III 19 417 1.1E-97 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS00975 647070966b3d5f9ae25fd5bbf68b1f95 422 SUPERFAMILY SSF53383 13 421 1.65E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS00975 647070966b3d5f9ae25fd5bbf68b1f95 422 PIRSF PIRSF000521 4 146 1.9E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS00975 647070966b3d5f9ae25fd5bbf68b1f95 422 PIRSF PIRSF000521 122 421 1.9E-36 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS00975 647070966b3d5f9ae25fd5bbf68b1f95 422 Gene3D G3DSA:3.90.1150.10 5 155 5.6E-34 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS00975 647070966b3d5f9ae25fd5bbf68b1f95 422 Gene3D G3DSA:3.90.1150.10 304 422 2.3E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS00975 647070966b3d5f9ae25fd5bbf68b1f95 422 Gene3D G3DSA:3.40.640.10 172 303 7.9E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS05025 993e32f47df3c0c5d54f59b542edc160 234 Pfam PF12787 EcsC protein family 6 229 1.0E-70 T 29-03-2018 IPR024787 EcsC protein CXR48_RS05025 993e32f47df3c0c5d54f59b542edc160 234 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 1 229 2.0E-85 T 29-03-2018 CXR48_RS18725 a355c738f3eed6f9a908cb184e2060c4 271 SUPERFAMILY SSF51182 5 257 3.21E-71 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS18725 a355c738f3eed6f9a908cb184e2060c4 271 Gene3D G3DSA:2.60.120.10 20 125 1.4E-32 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS18725 a355c738f3eed6f9a908cb184e2060c4 271 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 22 268 2.2E-107 T 29-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CXR48_RS18725 a355c738f3eed6f9a908cb184e2060c4 271 Pfam PF04962 KduI/IolB family 13 268 3.7E-107 T 29-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CXR48_RS18725 a355c738f3eed6f9a908cb184e2060c4 271 Gene3D G3DSA:2.60.120.10 126 271 1.1E-58 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS18725 a355c738f3eed6f9a908cb184e2060c4 271 Hamap MF_01673 5-deoxy-glucuronate isomerase [iolB]. 1 271 62.123 T 29-03-2018 IPR023770 5-deoxy-glucuronate isomerase, Bacilli GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CXR48_RS18725 a355c738f3eed6f9a908cb184e2060c4 271 PIRSF PIRSF036628 1 271 3.6E-113 T 29-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CXR48_RS00360 8c9b8ec07d632733b98dbf1a1f89bd38 86 Pfam PF01479 S4 domain 1 47 5.4E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS00360 8c9b8ec07d632733b98dbf1a1f89bd38 86 SMART SM00363 1 64 1.6E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS00360 8c9b8ec07d632733b98dbf1a1f89bd38 86 Gene3D G3DSA:3.10.290.10 1 85 2.3E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS00360 8c9b8ec07d632733b98dbf1a1f89bd38 86 SUPERFAMILY SSF55174 1 76 1.83E-20 T 29-03-2018 CXR48_RS00360 8c9b8ec07d632733b98dbf1a1f89bd38 86 PIRSF PIRSF038881 1 86 8.7E-35 T 29-03-2018 IPR025490 RNA-binding protein, HP1423 type CXR48_RS02310 3d62b5c25f9a020f80a440a10665b299 273 Gene3D G3DSA:1.20.1260.10 1 198 3.3E-72 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS02310 3d62b5c25f9a020f80a440a10665b299 273 Gene3D G3DSA:3.30.1530.10 208 267 2.9E-18 T 29-03-2018 IPR027407 Manganese catalase, domain 2 CXR48_RS02310 3d62b5c25f9a020f80a440a10665b299 273 Pfam PF05067 Manganese containing catalase 1 268 2.6E-126 T 29-03-2018 IPR007760 Manganese catalase CXR48_RS02310 3d62b5c25f9a020f80a440a10665b299 273 SUPERFAMILY SSF47240 1 271 3.29E-98 T 29-03-2018 IPR009078 Ferritin-like superfamily CXR48_RS12550 49e5b611226f6ed124afc52aaa977e01 213 SUPERFAMILY SSF53335 7 196 2.84E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS12550 49e5b611226f6ed124afc52aaa977e01 213 Hamap MF_02100 Uncharacterized methyltransferase . 2 213 44.229 T 29-03-2018 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 CXR48_RS12550 49e5b611226f6ed124afc52aaa977e01 213 Gene3D G3DSA:3.40.50.150 24 213 3.1E-33 T 29-03-2018 CXR48_RS12550 49e5b611226f6ed124afc52aaa977e01 213 Pfam PF13649 Methyltransferase domain 49 137 1.9E-14 T 29-03-2018 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 PIRSF PIRSF000106 42 407 5.7E-87 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 Gene3D G3DSA:3.40.50.10380 3 157 2.2E-41 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 SUPERFAMILY SSF51735 160 405 5.21E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 SUPERFAMILY SSF53223 6 158 3.09E-57 T 29-03-2018 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 PRINTS PR00072 Malic enzyme signature 187 203 1.5E-8 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 PRINTS PR00072 Malic enzyme signature 77 99 1.5E-8 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 PRINTS PR00072 Malic enzyme signature 156 172 1.5E-8 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 SMART SM00919 160 384 2.6E-134 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 5.2E-26 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 Gene3D G3DSA:3.40.50.720 158 406 5.3E-89 T 29-03-2018 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 Pfam PF00390 Malic enzyme, N-terminal domain 16 148 1.6E-30 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS13520 ee81c339f47b1ae0ecc46009833348ff 410 SMART SM01274 15 148 4.3E-85 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CXR48_RS09395 dac22d50fcaf92f057b354063924de6d 192 SUPERFAMILY SSF46785 10 148 2.86E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09395 dac22d50fcaf92f057b354063924de6d 192 Pfam PF12802 MarR family 38 97 1.4E-10 T 29-03-2018 CXR48_RS09395 dac22d50fcaf92f057b354063924de6d 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 3.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS09395 dac22d50fcaf92f057b354063924de6d 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 3.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS09395 dac22d50fcaf92f057b354063924de6d 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 3.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS09395 dac22d50fcaf92f057b354063924de6d 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 3.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS09395 dac22d50fcaf92f057b354063924de6d 192 SMART SM00347 33 133 1.6E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS09395 dac22d50fcaf92f057b354063924de6d 192 Gene3D G3DSA:1.10.10.10 1 191 4.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01670 5aaacd96702862caa0d23ede018e41df 262 Pfam PF01261 Xylose isomerase-like TIM barrel 20 217 1.1E-29 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS01670 5aaacd96702862caa0d23ede018e41df 262 Gene3D G3DSA:3.20.20.150 1 257 1.3E-48 T 29-03-2018 CXR48_RS01670 5aaacd96702862caa0d23ede018e41df 262 SUPERFAMILY SSF51658 1 245 4.45E-46 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 SUPERFAMILY SSF54427 27 145 7.45E-29 T 29-03-2018 IPR032710 NTF2-like domain CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 662 3.8E-73 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 SUPERFAMILY SSF56519 148 333 4.58E-36 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 Gene3D G3DSA:3.40.710.10 333 666 5.2E-64 T 29-03-2018 CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 25 146 4.3E-33 T 29-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 Gene3D G3DSA:3.90.1310.10 229 332 1.2E-20 T 29-03-2018 CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 Gene3D G3DSA:3.30.1390.30 176 228 2.0E-19 T 29-03-2018 CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 SUPERFAMILY SSF56601 334 665 1.35E-76 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 Gene3D G3DSA:3.10.450.100 23 141 1.5E-30 T 29-03-2018 CXR48_RS02135 d7276ebb7ac7dfcb5b34ae18f19cc7be 667 Pfam PF03717 Penicillin-binding Protein dimerisation domain 154 321 1.4E-33 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 SUPERFAMILY SSF52540 72 323 1.3E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 Gene3D G3DSA:3.40.50.300 70 252 7.2E-25 T 29-03-2018 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 Gene3D G3DSA:3.40.50.300 392 607 4.3E-50 T 29-03-2018 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 Pfam PF07724 AAA domain (Cdc48 subfamily) 436 602 1.1E-51 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 608 679 4.7E-23 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 SMART SM00382 110 254 7.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 SMART SM00382 437 609 2.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 Gene3D G3DSA:1.10.8.60 608 697 1.4E-22 T 29-03-2018 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 486 504 4.1E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 441 459 4.1E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 515 533 4.1E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 548 562 4.1E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 SUPERFAMILY SSF52540 386 686 1.15E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 471 489 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 Pfam PF02151 UvrB/uvrC motif 325 359 1.3E-5 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 115 246 3.5E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 SMART SM01086 608 695 7.3E-30 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 Gene3D G3DSA:1.10.8.60 253 387 1.1E-37 T 29-03-2018 CXR48_RS06780 e5fce686a1dc69adc4cde5778d6dba0a 698 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 205 217 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CXR48_RS08320 86244228c0cfb291becb7990ddb1af6a 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 7.0E-38 T 29-03-2018 CXR48_RS08320 86244228c0cfb291becb7990ddb1af6a 89 Gene3D G3DSA:1.10.287.10 2 89 2.0E-37 T 29-03-2018 CXR48_RS08320 86244228c0cfb291becb7990ddb1af6a 89 SMART SM01387 8 88 7.5E-52 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08320 86244228c0cfb291becb7990ddb1af6a 89 Pfam PF00312 Ribosomal protein S15 8 88 1.8E-38 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08320 86244228c0cfb291becb7990ddb1af6a 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 1.2E-42 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS08320 86244228c0cfb291becb7990ddb1af6a 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS08320 86244228c0cfb291becb7990ddb1af6a 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.218 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS08320 86244228c0cfb291becb7990ddb1af6a 89 SUPERFAMILY SSF47060 3 89 7.36E-37 T 29-03-2018 IPR009068 S15/NS1, RNA-binding CXR48_RS18985 ff90396050dbad13bce2ec434c2c8439 440 SUPERFAMILY SSF53850 8 432 3.69E-19 T 29-03-2018 CXR48_RS18985 ff90396050dbad13bce2ec434c2c8439 440 Gene3D G3DSA:3.90.76.10 73 152 1.2E-4 T 29-03-2018 CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 SUPERFAMILY SSF47757 3 66 8.37E-11 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 SUPERFAMILY SSF53335 67 239 3.2E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 Pfam PF03705 CheR methyltransferase, all-alpha domain 4 54 8.3E-12 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 Pfam PF01739 CheR methyltransferase, SAM binding domain 67 249 9.0E-65 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 Gene3D G3DSA:1.10.155.10 2 65 2.0E-9 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 SMART SM00138 1 254 7.5E-120 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 Gene3D G3DSA:3.40.50.150 66 256 1.7E-49 T 29-03-2018 CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 PRINTS PR00996 Glutamate methyltransferase family signature 214 237 4.1E-41 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 PRINTS PR00996 Glutamate methyltransferase family signature 128 144 4.1E-41 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 PRINTS PR00996 Glutamate methyltransferase family signature 195 209 4.1E-41 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 4.1E-41 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 PRINTS PR00996 Glutamate methyltransferase family signature 96 116 4.1E-41 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CXR48_RS10775 d265b7a5dbbe962d0da0db94d5e67fcc 256 PRINTS PR00996 Glutamate methyltransferase family signature 23 36 4.1E-41 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CXR48_RS17120 789fad09cb92447852139afb31bf5bdc 262 SUPERFAMILY SSF103032 5 262 7.59E-86 T 29-03-2018 IPR015315 Protein of unknown function DUF1963 CXR48_RS17120 789fad09cb92447852139afb31bf5bdc 262 Gene3D G3DSA:2.30.320.10 1 262 6.1E-73 T 29-03-2018 CXR48_RS17120 789fad09cb92447852139afb31bf5bdc 262 Pfam PF09234 Domain of unknown function (DUF1963) 40 261 1.4E-65 T 29-03-2018 IPR015315 Protein of unknown function DUF1963 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 172 6.5E-53 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 694 7.2E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 764 775 7.2E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 628 643 7.2E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 605 627 7.2E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 730 7.2E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 742 753 7.2E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 651 674 7.2E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 796 812 7.2E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 839 7.2E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 SMART SM00475 5 264 8.6E-151 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 SUPERFAMILY SSF56672 472 879 6.0E-160 T 29-03-2018 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 Gene3D G3DSA:1.20.1060.10 422 603 3.2E-60 T 29-03-2018 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 SMART SM00482 636 843 2.6E-124 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 268 2.4E-35 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 SUPERFAMILY SSF88723 4 172 1.64E-54 T 29-03-2018 IPR029060 PIN domain-like CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 TIGRFAM TIGR00593 pola: DNA polymerase I 7 879 0.0 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 Gene3D G3DSA:1.10.150.20 187 265 1.5E-30 T 29-03-2018 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 SMART SM00474 301 469 2.9E-24 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 Gene3D G3DSA:3.40.50.1010 5 186 1.6E-66 T 29-03-2018 IPR029060 PIN domain-like CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 Pfam PF00476 DNA polymerase family A 501 877 4.9E-162 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 SUPERFAMILY SSF53098 303 471 1.27E-43 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 SMART SM00279 175 210 6.3E-17 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 ProSitePatterns PS00447 DNA polymerase family A signature. 705 724 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 Gene3D G3DSA:3.30.70.370 604 701 1.3E-16 T 29-03-2018 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 Gene3D G3DSA:3.30.70.370 705 879 2.4E-53 T 29-03-2018 CXR48_RS13445 803d2103f8710ccfc1d013d3797d35fd 879 SUPERFAMILY SSF47807 173 287 3.59E-34 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CXR48_RS02810 98589656ff118794b0fcdc1f8512bfca 240 SUPERFAMILY SSF52317 27 238 1.3E-36 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS02810 98589656ff118794b0fcdc1f8512bfca 240 Pfam PF07722 Peptidase C26 5 218 4.6E-66 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CXR48_RS02810 98589656ff118794b0fcdc1f8512bfca 240 Gene3D G3DSA:3.40.50.880 1 240 1.1E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS19100 c3bc9d057b880c1fa878726e3c34416f 430 Pfam PF00534 Glycosyl transferases group 1 248 406 4.1E-34 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CXR48_RS19100 c3bc9d057b880c1fa878726e3c34416f 430 Gene3D G3DSA:3.40.50.2000 253 412 6.8E-43 T 29-03-2018 CXR48_RS19100 c3bc9d057b880c1fa878726e3c34416f 430 SUPERFAMILY SSF53756 53 428 1.69E-77 T 29-03-2018 CXR48_RS19100 c3bc9d057b880c1fa878726e3c34416f 430 Gene3D G3DSA:3.40.50.2000 46 252 7.6E-6 T 29-03-2018 CXR48_RS19100 c3bc9d057b880c1fa878726e3c34416f 430 Pfam PF13439 Glycosyltransferase Family 4 65 244 3.5E-18 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CXR48_RS11155 c3eebe2b6f8bace999a50f3ca1e1be6d 75 Pfam PF14004 Protein of unknown function (DUF4227) 6 75 2.1E-32 T 29-03-2018 IPR025321 Protein of unknown function DUF4227 CXR48_RS16195 5f5af02f04f201be66dea2f8480843da 597 Pfam PF02719 Polysaccharide biosynthesis protein 271 552 1.4E-121 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CXR48_RS16195 5f5af02f04f201be66dea2f8480843da 597 SUPERFAMILY SSF51735 268 532 1.62E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS16195 5f5af02f04f201be66dea2f8480843da 597 Gene3D G3DSA:3.40.50.720 125 252 3.4E-25 T 29-03-2018 CXR48_RS16195 5f5af02f04f201be66dea2f8480843da 597 Gene3D G3DSA:3.40.50.720 264 592 8.9E-62 T 29-03-2018 CXR48_RS16195 5f5af02f04f201be66dea2f8480843da 597 SUPERFAMILY SSF51735 129 258 1.02E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS16195 5f5af02f04f201be66dea2f8480843da 597 Pfam PF13727 CoA-binding domain 64 226 1.4E-16 T 29-03-2018 CXR48_RS16460 3bbe2cb3e77879a5c46a3e61acd46799 390 Gene3D G3DSA:3.30.930.10 1 330 2.9E-59 T 29-03-2018 CXR48_RS16460 3bbe2cb3e77879a5c46a3e61acd46799 390 SUPERFAMILY SSF55681 4 320 1.45E-62 T 29-03-2018 CXR48_RS16460 3bbe2cb3e77879a5c46a3e61acd46799 390 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 11 320 8.4E-95 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CXR48_RS16460 3bbe2cb3e77879a5c46a3e61acd46799 390 PIRSF PIRSF001549 1 385 2.3E-81 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CXR48_RS16460 3bbe2cb3e77879a5c46a3e61acd46799 390 Pfam PF13393 Histidyl-tRNA synthetase 9 316 3.0E-75 T 29-03-2018 CXR48_RS16460 3bbe2cb3e77879a5c46a3e61acd46799 390 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 370 34.413 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CXR48_RS12920 956a3e1d5bc1859c85834413823c4384 189 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 183 3.1E-70 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CXR48_RS12920 956a3e1d5bc1859c85834413823c4384 189 SUPERFAMILY SSF52972 2 184 7.85E-63 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CXR48_RS12920 956a3e1d5bc1859c85834413823c4384 189 Pfam PF02545 Maf-like protein 4 184 2.9E-59 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CXR48_RS12920 956a3e1d5bc1859c85834413823c4384 189 Hamap MF_00528 Septum formation protein Maf [maf]. 4 189 32.049 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CXR48_RS12920 956a3e1d5bc1859c85834413823c4384 189 PIRSF PIRSF006305 1 189 1.7E-64 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CXR48_RS12920 956a3e1d5bc1859c85834413823c4384 189 Gene3D G3DSA:3.90.950.10 1 189 1.5E-74 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CXR48_RS15315 c8d2254cfe0566ee6af6d3255d8e8b85 106 Pfam PF00085 Thioredoxin 13 97 7.4E-10 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CXR48_RS15315 c8d2254cfe0566ee6af6d3255d8e8b85 106 SUPERFAMILY SSF52833 6 98 5.54E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS15315 c8d2254cfe0566ee6af6d3255d8e8b85 106 Gene3D G3DSA:3.40.30.10 1 105 2.1E-14 T 29-03-2018 CXR48_RS10600 e56a8f9eaa8b8f1dfcb801c47ce23bba 161 Gene3D G3DSA:3.10.450.40 99 161 3.4E-14 T 29-03-2018 CXR48_RS10600 e56a8f9eaa8b8f1dfcb801c47ce23bba 161 Gene3D G3DSA:3.10.450.40 30 94 8.7E-24 T 29-03-2018 CXR48_RS10600 e56a8f9eaa8b8f1dfcb801c47ce23bba 161 SUPERFAMILY SSF54403 99 160 8.84E-16 T 29-03-2018 CXR48_RS10600 e56a8f9eaa8b8f1dfcb801c47ce23bba 161 SUPERFAMILY SSF54403 35 99 4.76E-16 T 29-03-2018 CXR48_RS12715 35f20b09642b5d11fc2849483bc48843 147 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 146 1.4E-66 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CXR48_RS12715 35f20b09642b5d11fc2849483bc48843 147 Gene3D G3DSA:3.50.80.10 1 145 7.8E-60 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CXR48_RS12715 35f20b09642b5d11fc2849483bc48843 147 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 35.405 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CXR48_RS12715 35f20b09642b5d11fc2849483bc48843 147 SUPERFAMILY SSF69500 1 145 8.76E-59 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CXR48_RS12715 35f20b09642b5d11fc2849483bc48843 147 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 3.6E-57 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CXR48_RS16870 967e8b6801dd3536a70fe5393b4e5230 470 SUPERFAMILY SSF53448 10 255 3.56E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16870 967e8b6801dd3536a70fe5393b4e5230 470 Gene3D G3DSA:3.90.550.10 7 260 1.6E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16870 967e8b6801dd3536a70fe5393b4e5230 470 Pfam PF13489 Methyltransferase domain 259 413 1.4E-18 T 29-03-2018 CXR48_RS16870 967e8b6801dd3536a70fe5393b4e5230 470 SUPERFAMILY SSF53335 254 436 4.84E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS16870 967e8b6801dd3536a70fe5393b4e5230 470 Pfam PF00535 Glycosyl transferase family 2 15 136 6.2E-26 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS16870 967e8b6801dd3536a70fe5393b4e5230 470 Gene3D G3DSA:3.40.50.150 261 469 9.1E-33 T 29-03-2018 CXR48_RS05855 413b3f3b0966e9bb93c231fc5ffe3500 240 Gene3D G3DSA:3.40.50.1820 2 240 2.0E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS05855 413b3f3b0966e9bb93c231fc5ffe3500 240 Pfam PF00756 Putative esterase 15 238 2.2E-58 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CXR48_RS05855 413b3f3b0966e9bb93c231fc5ffe3500 240 SUPERFAMILY SSF53474 6 237 1.49E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS18300 54963b812b7a8ca772d9fe54a2df0ba3 337 SUPERFAMILY SSF81345 9 334 2.62E-76 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS18300 54963b812b7a8ca772d9fe54a2df0ba3 337 Gene3D G3DSA:1.10.3470.10 5 337 1.5E-63 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS18300 54963b812b7a8ca772d9fe54a2df0ba3 337 Pfam PF01032 FecCD transport family 22 334 3.0E-87 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CXR48_RS07620 c7c8902154fe5c1ab0c6d613f7b2aae8 309 Pfam PF03419 Sporulation factor SpoIIGA 3 299 9.3E-84 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CXR48_RS07620 c7c8902154fe5c1ab0c6d613f7b2aae8 309 PIRSF PIRSF018571 1 302 1.1E-97 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CXR48_RS07620 c7c8902154fe5c1ab0c6d613f7b2aae8 309 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 2 300 9.1E-89 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CXR48_RS16290 431670a56c8a55491cb00e9715cfae01 487 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 27 331 1.1E-112 T 29-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CXR48_RS16290 431670a56c8a55491cb00e9715cfae01 487 SUPERFAMILY SSF49899 331 484 2.61E-34 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CXR48_RS16290 431670a56c8a55491cb00e9715cfae01 487 SUPERFAMILY SSF75005 19 332 8.03E-121 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS16290 431670a56c8a55491cb00e9715cfae01 487 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 16 455 2.0E-152 T 29-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CXR48_RS16290 431670a56c8a55491cb00e9715cfae01 487 SMART SM00640 27 444 1.5E-152 T 29-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CXR48_RS16290 431670a56c8a55491cb00e9715cfae01 487 Gene3D G3DSA:2.115.10.20 32 354 1.7E-112 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS16290 431670a56c8a55491cb00e9715cfae01 487 Gene3D G3DSA:2.60.120.560 355 481 9.3E-32 T 29-03-2018 CXR48_RS16290 431670a56c8a55491cb00e9715cfae01 487 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 349 478 3.9E-30 T 29-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CXR48_RS16290 431670a56c8a55491cb00e9715cfae01 487 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 27 40 - T 29-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CXR48_RS02045 98dfaa19330a524bef055c48dc3c54ee 542 Gene3D G3DSA:2.60.40.1220 23 121 2.1E-23 T 29-03-2018 CXR48_RS02045 98dfaa19330a524bef055c48dc3c54ee 542 Pfam PF04234 CopC domain 24 120 2.8E-19 T 29-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CXR48_RS02045 98dfaa19330a524bef055c48dc3c54ee 542 SUPERFAMILY SSF81296 23 120 4.76E-22 T 29-03-2018 IPR014756 Immunoglobulin E-set CXR48_RS02045 98dfaa19330a524bef055c48dc3c54ee 542 Pfam PF05425 Copper resistance protein D 328 420 2.2E-17 T 29-03-2018 IPR008457 Copper resistance protein D GO:0016021 CXR48_RS02045 98dfaa19330a524bef055c48dc3c54ee 542 Gene3D G3DSA:2.60.40.10 314 485 2.6E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS02045 98dfaa19330a524bef055c48dc3c54ee 542 Pfam PF13115 YtkA-like 455 525 5.9E-6 T 29-03-2018 IPR032693 YtkA-like domain CXR48_RS14835 3b2021f104f9bb1207e5b6d3e48d5333 1041 Gene3D G3DSA:1.20.120.330 498 624 1.4E-8 T 29-03-2018 CXR48_RS14835 3b2021f104f9bb1207e5b6d3e48d5333 1041 TIGRFAM TIGR03929 T7_esaA_Nterm: type VII secretion protein EsaA 11 204 4.2E-76 T 29-03-2018 IPR023838 Type VII secretion system EsaA GO:0016021 CXR48_RS14835 3b2021f104f9bb1207e5b6d3e48d5333 1041 Gene3D G3DSA:3.40.1710.10 39 194 4.1E-20 T 29-03-2018 CXR48_RS14835 3b2021f104f9bb1207e5b6d3e48d5333 1041 Gene3D G3DSA:1.20.120.20 678 834 0.098 T 29-03-2018 CXR48_RS14835 3b2021f104f9bb1207e5b6d3e48d5333 1041 Gene3D G3DSA:1.20.1480.30 195 319 0.0044 T 29-03-2018 CXR48_RS17960 5e1f9749888341b68efce9dd63532806 140 ProDom PD705231 YWDI GROUP-SPECIFIC 34 140 6.0E-28 T 29-03-2018 IPR035218 Protein of unknown function DUF5327 CXR48_RS17960 5e1f9749888341b68efce9dd63532806 140 Pfam PF17261 Family of unknown function (DUF5327) 33 140 2.2E-24 T 29-03-2018 IPR035218 Protein of unknown function DUF5327 CXR48_RS18060 79f363d0580ad5c0b858943fc9bd4cf2 165 SUPERFAMILY SSF55729 18 162 1.49E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS18060 79f363d0580ad5c0b858943fc9bd4cf2 165 Pfam PF00583 Acetyltransferase (GNAT) family 41 142 1.0E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS18060 79f363d0580ad5c0b858943fc9bd4cf2 165 Gene3D G3DSA:3.40.630.30 14 165 2.6E-27 T 29-03-2018 CXR48_RS01990 d4f3f7d87ab9db2278d97627c9b55a1b 473 Pfam PF07690 Major Facilitator Superfamily 20 410 4.4E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS01990 d4f3f7d87ab9db2278d97627c9b55a1b 473 Gene3D G3DSA:1.20.1250.20 260 473 2.1E-24 T 29-03-2018 CXR48_RS01990 d4f3f7d87ab9db2278d97627c9b55a1b 473 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 423 2.5E-105 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CXR48_RS01990 d4f3f7d87ab9db2278d97627c9b55a1b 473 SUPERFAMILY SSF103473 10 198 4.32E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01990 d4f3f7d87ab9db2278d97627c9b55a1b 473 SUPERFAMILY SSF103473 249 466 4.32E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01990 d4f3f7d87ab9db2278d97627c9b55a1b 473 Gene3D G3DSA:1.20.1250.20 3 201 4.6E-32 T 29-03-2018 CXR48_RS01990 d4f3f7d87ab9db2278d97627c9b55a1b 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 1.1E-7 T 29-03-2018 CXR48_RS01990 d4f3f7d87ab9db2278d97627c9b55a1b 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 1.1E-7 T 29-03-2018 CXR48_RS01990 d4f3f7d87ab9db2278d97627c9b55a1b 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 1.1E-7 T 29-03-2018 CXR48_RS09020 de0fd7cb8c80bb536c3ae91af93a8406 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 197 8.6E-54 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CXR48_RS09020 de0fd7cb8c80bb536c3ae91af93a8406 211 Pfam PF01081 KDPG and KHG aldolase 8 191 1.1E-43 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CXR48_RS09020 de0fd7cb8c80bb536c3ae91af93a8406 211 SUPERFAMILY SSF51569 4 201 1.19E-57 T 29-03-2018 CXR48_RS09020 de0fd7cb8c80bb536c3ae91af93a8406 211 Gene3D G3DSA:3.20.20.70 5 202 6.0E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS14425 4dda96622c289f14b79ea3963dd2414c 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS14425 4dda96622c289f14b79ea3963dd2414c 490 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 6 474 3.5E-237 T 29-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 CXR48_RS14425 4dda96622c289f14b79ea3963dd2414c 490 Gene3D G3DSA:3.40.605.10 1 264 3.4E-97 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS14425 4dda96622c289f14b79ea3963dd2414c 490 Gene3D G3DSA:3.40.309.10 265 462 3.9E-78 T 29-03-2018 CXR48_RS14425 4dda96622c289f14b79ea3963dd2414c 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS14425 4dda96622c289f14b79ea3963dd2414c 490 SUPERFAMILY SSF53720 4 481 7.2E-171 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS14425 4dda96622c289f14b79ea3963dd2414c 490 Pfam PF00171 Aldehyde dehydrogenase family 11 476 1.3E-180 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS03990 2566f63e32c3af7700362d9e67dc63e0 60 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 18.508 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CXR48_RS03990 2566f63e32c3af7700362d9e67dc63e0 60 Pfam PF08141 Small acid-soluble spore protein H family 2 58 1.2E-19 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CXR48_RS03990 2566f63e32c3af7700362d9e67dc63e0 60 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 2 58 7.0E-20 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CXR48_RS03990 2566f63e32c3af7700362d9e67dc63e0 60 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 59 1.0E-14 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CXR48_RS15020 4e333a476ce7a49ffa834c00aaf11ff8 120 SUPERFAMILY SSF89360 4 98 2.55E-30 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CXR48_RS15020 4e333a476ce7a49ffa834c00aaf11ff8 120 Gene3D G3DSA:2.60.300.12 4 113 1.2E-38 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CXR48_RS15020 4e333a476ce7a49ffa834c00aaf11ff8 120 Pfam PF01521 Iron-sulphur cluster biosynthesis 5 105 2.3E-20 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CXR48_RS15020 4e333a476ce7a49ffa834c00aaf11ff8 120 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 91 108 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CXR48_RS15020 4e333a476ce7a49ffa834c00aaf11ff8 120 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 5 109 5.9E-39 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CXR48_RS11790 4ba1cfa30ab67ef7494c949baf2b87fd 491 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 60.211 T 29-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CXR48_RS11790 4ba1cfa30ab67ef7494c949baf2b87fd 491 Gene3D G3DSA:3.90.1150.10 345 470 6.8E-46 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS11790 4ba1cfa30ab67ef7494c949baf2b87fd 491 SUPERFAMILY SSF53383 10 483 1.57E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS11790 4ba1cfa30ab67ef7494c949baf2b87fd 491 Pfam PF02347 Glycine cleavage system P-protein 46 300 5.0E-9 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CXR48_RS11790 4ba1cfa30ab67ef7494c949baf2b87fd 491 Gene3D G3DSA:3.40.640.10 83 344 3.0E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS10455 262b88fca8ce791083e5fcccadf1bc0c 398 Gene3D G3DSA:1.10.150.130 59 173 4.0E-18 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CXR48_RS10455 262b88fca8ce791083e5fcccadf1bc0c 398 Pfam PF14657 Arm DNA-binding domain 11 55 1.6E-5 T 29-03-2018 IPR028259 AP2-like integrase, N-terminal domain CXR48_RS10455 262b88fca8ce791083e5fcccadf1bc0c 398 Gene3D G3DSA:1.10.443.10 179 383 1.2E-40 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CXR48_RS10455 262b88fca8ce791083e5fcccadf1bc0c 398 SUPERFAMILY SSF56349 64 381 1.27E-62 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CXR48_RS10455 262b88fca8ce791083e5fcccadf1bc0c 398 Pfam PF00589 Phage integrase family 179 374 5.2E-28 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 Pfam PF00871 Acetokinase family 10 356 7.9E-70 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 SUPERFAMILY SSF53067 9 177 5.05E-73 T 29-03-2018 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 Gene3D G3DSA:3.30.420.40 7 183 9.7E-60 T 29-03-2018 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 10 21 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 PIRSF PIRSF036458 6 361 1.5E-174 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 184 201 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 9 359 5.1E-176 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 SUPERFAMILY SSF53067 122 352 2.65E-55 T 29-03-2018 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 PRINTS PR00471 Acetate kinase family signature 302 318 4.9E-14 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 PRINTS PR00471 Acetate kinase family signature 10 21 4.9E-14 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 PRINTS PR00471 Acetate kinase family signature 279 292 4.9E-14 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 PRINTS PR00471 Acetate kinase family signature 184 205 4.9E-14 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 Hamap MF_00542 Probable butyrate kinase [buk]. 1 371 172.022 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CXR48_RS11530 19e5478a392ad64463646eace7b20524 371 Gene3D G3DSA:3.30.420.40 184 363 2.9E-44 T 29-03-2018 CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 207 396 2.3E-79 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 PIRSF PIRSF001259 1 398 3.8E-193 T 29-03-2018 CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 394 57.202 T 29-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 398 42.077 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 Pfam PF00925 GTP cyclohydrolase II 207 372 9.3E-76 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 4.7E-85 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 SUPERFAMILY SSF55821 2 199 2.52E-83 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 38.063 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 SUPERFAMILY SSF142695 203 375 5.1E-72 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 Gene3D G3DSA:3.90.870.10 1 210 5.0E-91 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CXR48_RS11040 d531f2fc1d9209bb1a8382071388a9cc 398 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 4.2E-83 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS09430 606588b53e7717330274aea680d04a3d 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 3.9E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS09430 606588b53e7717330274aea680d04a3d 186 SUPERFAMILY SSF48498 79 183 1.67E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS09430 606588b53e7717330274aea680d04a3d 186 Gene3D G3DSA:1.10.10.60 1 50 6.8E-8 T 29-03-2018 CXR48_RS09430 606588b53e7717330274aea680d04a3d 186 Pfam PF13305 WHG domain 85 157 3.1E-12 T 29-03-2018 IPR025996 WHG domain CXR48_RS09430 606588b53e7717330274aea680d04a3d 186 Gene3D G3DSA:1.10.357.10 51 185 9.3E-15 T 29-03-2018 CXR48_RS09430 606588b53e7717330274aea680d04a3d 186 SUPERFAMILY SSF46689 8 71 1.18E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 ProSitePatterns PS00455 Putative AMP-binding domain signature. 612 623 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Gene3D G3DSA:3.40.50.1820 1059 1163 0.002 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Gene3D G3DSA:1.10.287.490 1164 1206 2.9E-30 T 29-03-2018 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 SUPERFAMILY SSF56801 429 986 1.57E-155 T 29-03-2018 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 SMART SM00823 Phosphopantetheine attachment site 974 1043 8.2E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 SUPERFAMILY SSF52777 15 192 6.23E-46 T 29-03-2018 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Gene3D G3DSA:1.10.1200.10 980 1045 3.4E-22 T 29-03-2018 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Gene3D G3DSA:3.40.50.980 461 617 2.6E-50 T 29-03-2018 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Gene3D G3DSA:3.40.50.980 618 774 6.3E-31 T 29-03-2018 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 891 1.8E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Gene3D G3DSA:3.30.559.10 2 215 2.7E-32 T 29-03-2018 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Pfam PF00550 Phosphopantetheine attachment site 976 1039 9.8E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Pfam PF00975 Thioesterase domain 1060 1254 8.0E-32 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Pfam PF00668 Condensation domain 9 451 1.9E-141 T 29-03-2018 IPR001242 Condensation domain CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 ProSitePatterns PS00012 Phosphopantetheine attachment site. 998 1013 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 SUPERFAMILY SSF53474 1055 1267 1.74E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Pfam PF00501 AMP-binding enzyme 470 867 5.6E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 SUPERFAMILY SSF52777 193 452 9.56E-52 T 29-03-2018 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 948 8.5E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Gene3D G3DSA:3.30.300.30 862 979 5.0E-39 T 29-03-2018 CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 SUPERFAMILY SSF47336 968 1039 3.27E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS01795 90b2334af23fe2b1277aa2334cdcb10b 1278 Gene3D G3DSA:2.30.38.10 777 857 7.4E-22 T 29-03-2018 CXR48_RS11045 1c121674e1da87e89a01b45018aa8436 215 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 201 9.4E-84 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS11045 1c121674e1da87e89a01b45018aa8436 215 SUPERFAMILY SSF63380 92 195 3.15E-31 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CXR48_RS11045 1c121674e1da87e89a01b45018aa8436 215 SUPERFAMILY SSF63380 1 89 6.63E-28 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CXR48_RS11045 1c121674e1da87e89a01b45018aa8436 215 Gene3D G3DSA:2.40.30.20 1 92 3.7E-31 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS11045 1c121674e1da87e89a01b45018aa8436 215 Gene3D G3DSA:2.40.30.20 93 190 3.5E-30 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS11045 1c121674e1da87e89a01b45018aa8436 215 PIRSF PIRSF000498 1 210 6.7E-80 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS11045 1c121674e1da87e89a01b45018aa8436 215 Pfam PF00677 Lumazine binding domain 3 86 1.4E-25 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS11045 1c121674e1da87e89a01b45018aa8436 215 Pfam PF00677 Lumazine binding domain 99 183 5.4E-22 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CXR48_RS07520 56122ff5e76c942d5e378262e05d39ff 59 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 19.34 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07520 56122ff5e76c942d5e378262e05d39ff 59 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 2.6E-26 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07520 56122ff5e76c942d5e378262e05d39ff 59 Pfam PF01783 Ribosomal L32p protein family 2 54 3.4E-25 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07520 56122ff5e76c942d5e378262e05d39ff 59 SUPERFAMILY SSF57829 1 54 3.54E-21 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 127 154 7.8E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 22 48 7.8E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 55 67 7.8E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 127 7.8E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 273 7.8E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 273 298 7.8E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 21 299 1.2E-135 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 PIRSF PIRSF036480 17 300 1.2E-112 T 29-03-2018 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 Gene3D G3DSA:3.40.50.170 107 296 1.7E-54 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 SUPERFAMILY SSF55021 21 101 1.16E-18 T 29-03-2018 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 Pfam PF00551 Formyl transferase 104 281 3.3E-43 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 Gene3D G3DSA:3.30.70.260 15 106 4.3E-26 T 29-03-2018 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 SUPERFAMILY SSF53328 104 300 8.37E-61 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 Pfam PF01842 ACT domain 22 83 1.2E-10 T 29-03-2018 IPR002912 ACT domain CXR48_RS06500 49592c783d9049e488f04c19a90f4ba5 300 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 17 299 47.647 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CXR48_RS08015 f7bd9455df7de7a512500c301bf02b10 93 TIGRFAM TIGR00789 flhB_rel: FlhB domain protein 8 87 2.0E-37 T 29-03-2018 IPR004683 Type III secretion system substrate exporter FlhB-like CXR48_RS08015 f7bd9455df7de7a512500c301bf02b10 93 Pfam PF01312 FlhB HrpN YscU SpaS Family 6 82 5.7E-20 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CXR48_RS08015 f7bd9455df7de7a512500c301bf02b10 93 Gene3D G3DSA:3.40.1690.10 6 88 1.0E-28 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CXR48_RS08015 f7bd9455df7de7a512500c301bf02b10 93 SUPERFAMILY SSF160544 5 86 3.92E-25 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CXR48_RS02435 a877455a47e079a7568f9dfd2739cb5d 273 Gene3D G3DSA:3.30.750.24 146 269 2.0E-13 T 29-03-2018 IPR002645 STAS domain CXR48_RS02435 a877455a47e079a7568f9dfd2739cb5d 273 Pfam PF01740 STAS domain 155 255 2.7E-14 T 29-03-2018 IPR002645 STAS domain CXR48_RS02435 a877455a47e079a7568f9dfd2739cb5d 273 SUPERFAMILY SSF52091 149 243 4.71E-16 T 29-03-2018 IPR002645 STAS domain CXR48_RS02435 a877455a47e079a7568f9dfd2739cb5d 273 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 9 134 4.0E-34 T 29-03-2018 CXR48_RS02435 a877455a47e079a7568f9dfd2739cb5d 273 Pfam PF08678 Rsbr N terminal 10 135 2.2E-31 T 29-03-2018 IPR014792 RsbS co-antagonist protein RsbRA N-terminal domain CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 SUPERFAMILY SSF103473 7 438 7.98E-83 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 Gene3D G3DSA:1.20.1250.20 5 201 5.9E-42 T 29-03-2018 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 Pfam PF00083 Sugar (and other) transporter 12 439 3.8E-124 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 PRINTS PR00171 Sugar transporter signature 341 362 4.1E-25 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 PRINTS PR00171 Sugar transporter signature 252 262 4.1E-25 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 PRINTS PR00171 Sugar transporter signature 364 376 4.1E-25 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 PRINTS PR00171 Sugar transporter signature 18 28 4.1E-25 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 PRINTS PR00171 Sugar transporter signature 101 120 4.1E-25 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 Gene3D G3DSA:1.20.1250.20 217 452 2.8E-43 T 29-03-2018 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 12 436 7.1E-116 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CXR48_RS16875 5434cf5402c3c48d42c3846e08c20a4a 458 ProSitePatterns PS00216 Sugar transport proteins signature 1. 296 312 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 SUPERFAMILY SSF46785 5 81 1.11E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 Pfam PF00571 CBS domain 147 203 4.6E-5 T 29-03-2018 IPR000644 CBS domain CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 Pfam PF00571 CBS domain 80 133 6.7E-7 T 29-03-2018 IPR000644 CBS domain CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 SUPERFAMILY SSF54631 70 204 1.04E-21 T 29-03-2018 CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 SMART SM00116 86 134 0.0014 T 29-03-2018 IPR000644 CBS domain CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 SMART SM00116 153 204 0.23 T 29-03-2018 IPR000644 CBS domain CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 Pfam PF08279 HTH domain 9 61 4.5E-13 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 Gene3D G3DSA:1.10.10.10 4 63 1.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 Gene3D G3DSA:3.10.580.10 64 211 4.5E-25 T 29-03-2018 CXR48_RS12120 c0056af1c707d98d9105e8e72abfabda 212 PIRSF PIRSF026546 4 210 6.6E-103 T 29-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 SUPERFAMILY SSF53850 89 286 1.36E-35 T 29-03-2018 CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 Gene3D G3DSA:3.40.190.10 175 246 3.0E-14 T 29-03-2018 CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 61 1.7E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 Gene3D G3DSA:3.40.190.10 87 174 1.5E-22 T 29-03-2018 CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 Gene3D G3DSA:1.10.10.10 1 86 3.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 SUPERFAMILY SSF46785 2 111 8.84E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11405 f769fe86840e3b61b7634cdd35d7fd12 292 Pfam PF03466 LysR substrate binding domain 88 285 6.0E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS12725 f9318133be09b2e96e8909abf5df7d53 170 Gene3D G3DSA:3.40.50.2020 1 168 4.2E-39 T 29-03-2018 CXR48_RS12725 f9318133be09b2e96e8909abf5df7d53 170 SUPERFAMILY SSF53271 2 164 3.27E-50 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS12725 f9318133be09b2e96e8909abf5df7d53 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 1.5E-70 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CXR48_RS12725 f9318133be09b2e96e8909abf5df7d53 170 Pfam PF00156 Phosphoribosyl transferase domain 35 149 7.1E-16 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CXR48_RS12725 f9318133be09b2e96e8909abf5df7d53 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.506 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CXR48_RS13185 319466b9a02b9b45e466c92063ec9bb6 562 Pfam PF00501 AMP-binding enzyme 32 458 3.7E-108 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS13185 319466b9a02b9b45e466c92063ec9bb6 562 Gene3D G3DSA:3.40.50.980 217 368 3.0E-45 T 29-03-2018 CXR48_RS13185 319466b9a02b9b45e466c92063ec9bb6 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 543 4.0E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS13185 319466b9a02b9b45e466c92063ec9bb6 562 Gene3D G3DSA:3.40.50.980 21 216 3.2E-42 T 29-03-2018 CXR48_RS13185 319466b9a02b9b45e466c92063ec9bb6 562 Gene3D G3DSA:2.30.38.10 369 452 1.6E-24 T 29-03-2018 CXR48_RS13185 319466b9a02b9b45e466c92063ec9bb6 562 SUPERFAMILY SSF56801 21 552 2.22E-152 T 29-03-2018 CXR48_RS13185 319466b9a02b9b45e466c92063ec9bb6 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS13185 319466b9a02b9b45e466c92063ec9bb6 562 Gene3D G3DSA:3.30.300.30 454 561 9.8E-30 T 29-03-2018 CXR48_RS12655 a95aa299b185c31d7336a294dbd4027b 152 SUPERFAMILY SSF50346 82 130 1.1E-5 T 29-03-2018 IPR011033 PRC-barrel-like CXR48_RS12655 a95aa299b185c31d7336a294dbd4027b 152 Pfam PF05239 PRC-barrel domain 8 52 4.3E-6 T 29-03-2018 IPR027275 PRC-barrel domain CXR48_RS12655 a95aa299b185c31d7336a294dbd4027b 152 Gene3D G3DSA:2.30.30.240 81 151 1.9E-4 T 29-03-2018 CXR48_RS12655 a95aa299b185c31d7336a294dbd4027b 152 Gene3D G3DSA:2.30.30.240 6 69 1.2E-8 T 29-03-2018 CXR48_RS10550 c87104720174dfbcf390ccabb8fe8010 81 Pfam PF17522 Family of unknown function (DUF5446) 1 64 2.7E-19 T 29-03-2018 IPR020252 Protein of unknown function DUF5446 CXR48_RS10550 c87104720174dfbcf390ccabb8fe8010 81 ProDom PD059812 YPPD 1 65 1.0E-10 T 29-03-2018 IPR020252 Protein of unknown function DUF5446 CXR48_RS03970 31add2d0dd83153aafadcb06fe099c35 342 Pfam PF02780 Transketolase, C-terminal domain 206 328 1.1E-39 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CXR48_RS03970 31add2d0dd83153aafadcb06fe099c35 342 Pfam PF02779 Transketolase, pyrimidine binding domain 5 192 3.6E-53 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS03970 31add2d0dd83153aafadcb06fe099c35 342 Gene3D G3DSA:3.40.50.920 207 337 8.1E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS03970 31add2d0dd83153aafadcb06fe099c35 342 SUPERFAMILY SSF52922 201 336 8.9E-40 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS03970 31add2d0dd83153aafadcb06fe099c35 342 Gene3D G3DSA:3.40.50.970 1 206 2.8E-63 T 29-03-2018 CXR48_RS03970 31add2d0dd83153aafadcb06fe099c35 342 SMART SM00861 5 192 4.8E-58 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS03970 31add2d0dd83153aafadcb06fe099c35 342 SUPERFAMILY SSF52518 3 216 7.85E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS00710 43007148d37f8b0dbe618e6dcbb24fef 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.6E-71 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CXR48_RS00710 43007148d37f8b0dbe618e6dcbb24fef 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.69 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CXR48_RS00710 43007148d37f8b0dbe618e6dcbb24fef 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 5.2E-67 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CXR48_RS00710 43007148d37f8b0dbe618e6dcbb24fef 156 PIRSF PIRSF002122 5 156 2.5E-60 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CXR48_RS00710 43007148d37f8b0dbe618e6dcbb24fef 156 Gene3D G3DSA:1.10.455.10 7 156 3.5E-61 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CXR48_RS00710 43007148d37f8b0dbe618e6dcbb24fef 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00710 43007148d37f8b0dbe618e6dcbb24fef 156 SUPERFAMILY SSF47973 1 149 7.06E-62 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CXR48_RS11885 34514d8982d3b8ce338c6e126c157f79 316 SUPERFAMILY SSF143865 57 221 3.01E-8 T 29-03-2018 CXR48_RS11885 34514d8982d3b8ce338c6e126c157f79 316 Pfam PF01544 CorA-like Mg2+ transporter protein 51 293 4.7E-35 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CXR48_RS11885 34514d8982d3b8ce338c6e126c157f79 316 Gene3D G3DSA:1.20.58.340 221 298 4.9E-19 T 29-03-2018 CXR48_RS11885 34514d8982d3b8ce338c6e126c157f79 316 SUPERFAMILY SSF144083 234 295 6.8E-18 T 29-03-2018 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 Pfam PF00890 FAD binding domain 6 369 5.0E-82 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 SUPERFAMILY SSF51905 6 246 1.33E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 SUPERFAMILY SSF51905 333 396 1.33E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 Gene3D G3DSA:1.20.58.100 389 489 2.6E-17 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 Pfam PF02910 Fumarate reductase flavoprotein C-term 413 499 2.0E-11 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 Gene3D G3DSA:3.50.50.60 5 289 3.4E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 Gene3D G3DSA:3.50.50.60 302 385 4.5E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 SUPERFAMILY SSF46977 411 504 7.06E-21 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 SUPERFAMILY SSF56425 220 329 2.09E-29 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS12830 8b0752ab4ad28bca25d5d716eb691be4 521 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 487 9.4E-186 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CXR48_RS06130 a397ced467115e9746ce50945df62522 221 SMART SM00448 2 114 7.7E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS06130 a397ced467115e9746ce50945df62522 221 SUPERFAMILY SSF46894 148 215 2.93E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS06130 a397ced467115e9746ce50945df62522 221 SUPERFAMILY SSF52172 1 129 5.12E-25 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS06130 a397ced467115e9746ce50945df62522 221 Gene3D G3DSA:1.10.10.10 121 218 1.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06130 a397ced467115e9746ce50945df62522 221 Gene3D G3DSA:3.40.50.2300 1 120 7.8E-25 T 29-03-2018 CXR48_RS06130 a397ced467115e9746ce50945df62522 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 6.0E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS06130 a397ced467115e9746ce50945df62522 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 6.0E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS06130 a397ced467115e9746ce50945df62522 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 6.0E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS06130 a397ced467115e9746ce50945df62522 221 Pfam PF00072 Response regulator receiver domain 4 114 3.0E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS06130 a397ced467115e9746ce50945df62522 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 207 1.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS06130 a397ced467115e9746ce50945df62522 221 SMART SM00421 151 208 8.2E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS12825 4fbcae48939d799e767fe6910156f4f2 282 SUPERFAMILY SSF51690 108 274 2.43E-58 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CXR48_RS12825 4fbcae48939d799e767fe6910156f4f2 282 Gene3D G3DSA:3.20.20.70 134 264 2.0E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS12825 4fbcae48939d799e767fe6910156f4f2 282 SUPERFAMILY SSF54675 5 107 5.1E-28 T 29-03-2018 CXR48_RS12825 4fbcae48939d799e767fe6910156f4f2 282 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 274 2.8E-99 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CXR48_RS12825 4fbcae48939d799e767fe6910156f4f2 282 PIRSF PIRSF006250 1 277 1.1E-102 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CXR48_RS12825 4fbcae48939d799e767fe6910156f4f2 282 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 108 273 1.1E-60 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CXR48_RS12825 4fbcae48939d799e767fe6910156f4f2 282 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 106 4.3E-26 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CXR48_RS12825 4fbcae48939d799e767fe6910156f4f2 282 Gene3D G3DSA:3.90.1170.20 1 133 4.0E-36 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 SMART SM00086 149 191 1.5E-7 T 29-03-2018 IPR001610 PAC motif CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 320 425 8.5E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 Gene3D G3DSA:1.10.287.130 204 273 2.4E-12 T 29-03-2018 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 SMART SM00091 78 146 1.6E-6 T 29-03-2018 IPR000014 PAS domain CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 SUPERFAMILY SSF55874 267 424 6.16E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 SMART SM00388 214 277 7.8E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 Gene3D G3DSA:3.30.565.10 277 434 3.3E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 275 2.3E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 Gene3D G3DSA:3.30.450.20 48 203 1.9E-23 T 29-03-2018 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 SUPERFAMILY SSF47384 201 275 2.55E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 SMART SM00387 320 426 1.3E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 SUPERFAMILY SSF55785 83 194 4.79E-19 T 29-03-2018 IPR000014 PAS domain CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 Pfam PF00989 PAS fold 80 188 1.0E-18 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS07160 777b02e187a47b733a02043f2d64f0af 434 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 82 198 1.0E-17 T 29-03-2018 IPR000014 PAS domain CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 40.498 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 Pfam PF00303 Thymidylate synthase 2 264 7.8E-129 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 29-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 1.8E-97 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 2.5E-43 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 Gene3D G3DSA:3.30.572.10 1 264 6.4E-134 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 4.4E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 4.4E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 4.4E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 4.4E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 4.4E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS10040 25ae601f6f5c567d293d5ed8153bced4 264 SUPERFAMILY SSF55831 1 264 2.09E-131 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 Gene3D G3DSA:3.30.930.10 1 204 1.7E-81 T 29-03-2018 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 288 2.0E-169 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 280 5.2E-147 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 1.9E-67 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 1.9E-67 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 1.9E-67 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 1.9E-67 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 1.9E-67 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 1.9E-67 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 Gene3D G3DSA:1.20.58.180 206 282 2.0E-35 T 29-03-2018 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 57.964 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CXR48_RS12130 78bc61f39450cee5ca9415262de1f193 295 SUPERFAMILY SSF55681 1 280 1.44E-131 T 29-03-2018 CXR48_RS15600 058e3adbf54286ca26cba954f59a849a 312 Gene3D G3DSA:3.40.50.1980 31 151 2.7E-20 T 29-03-2018 CXR48_RS15600 058e3adbf54286ca26cba954f59a849a 312 Gene3D G3DSA:3.40.50.1980 152 312 4.7E-31 T 29-03-2018 CXR48_RS15600 058e3adbf54286ca26cba954f59a849a 312 SUPERFAMILY SSF53807 37 307 1.37E-56 T 29-03-2018 CXR48_RS15600 058e3adbf54286ca26cba954f59a849a 312 Pfam PF01497 Periplasmic binding protein 59 288 1.1E-36 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 SUPERFAMILY SSF53067 3 140 2.45E-39 T 29-03-2018 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 Gene3D G3DSA:3.30.420.40 1 153 5.2E-36 T 29-03-2018 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 Pfam PF06723 MreB/Mbl protein 4 327 9.4E-150 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 Gene3D G3DSA:3.30.420.40 240 309 2.9E-8 T 29-03-2018 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 Gene3D G3DSA:3.30.420.40 154 239 6.3E-29 T 29-03-2018 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 327 1.1E-136 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 SUPERFAMILY SSF53067 143 325 1.53E-49 T 29-03-2018 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 5.8E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 5.8E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 5.8E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 5.8E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS17215 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 5.8E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS06445 e29c1807ee79e0baa0e4a2b5b3c5a21c 539 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 461 5.8E-86 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CXR48_RS06445 e29c1807ee79e0baa0e4a2b5b3c5a21c 539 SUPERFAMILY SSF53850 37 533 1.76E-134 T 29-03-2018 CXR48_RS06445 e29c1807ee79e0baa0e4a2b5b3c5a21c 539 PIRSF PIRSF002741 1 538 1.3E-119 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CXR48_RS06445 e29c1807ee79e0baa0e4a2b5b3c5a21c 539 Gene3D G3DSA:3.10.105.10 308 511 4.1E-52 T 29-03-2018 CXR48_RS06445 e29c1807ee79e0baa0e4a2b5b3c5a21c 539 Gene3D G3DSA:3.40.190.10 175 307 1.0E-40 T 29-03-2018 CXR48_RS06445 e29c1807ee79e0baa0e4a2b5b3c5a21c 539 Gene3D G3DSA:3.90.76.10 64 174 3.5E-33 T 29-03-2018 CXR48_RS00245 c565d84ec462e69909dd312decf8fb71 293 SUPERFAMILY SSF53790 14 232 3.79E-81 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS00245 c565d84ec462e69909dd312decf8fb71 293 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 17 290 1.0E-81 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS00245 c565d84ec462e69909dd312decf8fb71 293 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 215 1.4E-29 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS00245 c565d84ec462e69909dd312decf8fb71 293 PIRSF PIRSF005917 4 293 4.4E-103 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS00245 c565d84ec462e69909dd312decf8fb71 293 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 16 234 36.356 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS00245 c565d84ec462e69909dd312decf8fb71 293 Gene3D G3DSA:3.40.1010.10 14 124 2.8E-41 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS00245 c565d84ec462e69909dd312decf8fb71 293 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 94 105 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS00245 c565d84ec462e69909dd312decf8fb71 293 Gene3D G3DSA:3.30.950.10 125 237 1.8E-42 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 SUPERFAMILY SSF53738 304 455 3.81E-33 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 Gene3D G3DSA:3.40.120.10 13 213 3.1E-57 T 29-03-2018 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 SUPERFAMILY SSF55957 513 573 4.06E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 SUPERFAMILY SSF55957 447 481 4.06E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 451 5.0E-24 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 Gene3D G3DSA:3.30.310.50 467 579 4.8E-26 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 Gene3D G3DSA:3.40.120.10 337 455 1.2E-37 T 29-03-2018 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 312 1.1E-23 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 SUPERFAMILY SSF53738 30 225 1.1E-46 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 7.2E-6 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 7.2E-6 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 Gene3D G3DSA:3.40.120.10 214 336 2.3E-29 T 29-03-2018 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 SUPERFAMILY SSF53738 209 315 6.67E-20 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 504 550 5.0E-10 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 182 1.6E-42 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS04640 2800a65e439c12472bbd975ebc8aebb3 580 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 Pfam PF12833 Helix-turn-helix domain 152 230 7.6E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 SUPERFAMILY SSF51182 17 87 6.23E-13 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 Pfam PF07883 Cupin domain 18 76 1.6E-9 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 SMART SM00342 146 229 8.9E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 183 225 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 Gene3D G3DSA:1.10.10.60 129 183 1.2E-14 T 29-03-2018 CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 SUPERFAMILY SSF46689 130 179 2.15E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 Gene3D G3DSA:1.10.10.60 184 236 1.0E-10 T 29-03-2018 CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 Gene3D G3DSA:2.60.120.10 14 128 2.7E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS09425 f61c381f0918ec731cf0d6ac9b2a605c 236 SUPERFAMILY SSF46689 182 232 4.21E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS09130 a5e7c288ca1d21bb5a08359e9555dd3d 233 Gene3D G3DSA:3.40.1080.10 1 233 1.7E-97 T 29-03-2018 CXR48_RS09130 a5e7c288ca1d21bb5a08359e9555dd3d 233 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 19 34 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS09130 a5e7c288ca1d21bb5a08359e9555dd3d 233 SUPERFAMILY SSF100950 5 227 5.93E-88 T 29-03-2018 CXR48_RS09130 a5e7c288ca1d21bb5a08359e9555dd3d 233 Pfam PF01144 Coenzyme A transferase 9 216 8.7E-78 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS09130 a5e7c288ca1d21bb5a08359e9555dd3d 233 SMART SM00882 7 218 1.5E-93 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS09130 a5e7c288ca1d21bb5a08359e9555dd3d 233 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 5 216 3.0E-78 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 4.1E-203 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 4.0E-61 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 Gene3D G3DSA:3.40.47.10 262 412 4.2E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 2.7E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 SUPERFAMILY SSF53901 214 411 5.77E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 Gene3D G3DSA:3.40.47.10 6 259 1.1E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 SMART SM00825 Beta-ketoacyl synthase 6 412 1.2E-15 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 PIRSF PIRSF000447 1 412 5.3E-191 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CXR48_RS05565 ba3e1f39c0663b0d0566a78ef75e869c 412 SUPERFAMILY SSF53901 4 251 4.55E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS16595 94b71bec2d2e05de7bbd863f128ffc81 296 PIRSF PIRSF003097 1 296 1.6E-96 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CXR48_RS16595 94b71bec2d2e05de7bbd863f128ffc81 296 Pfam PF02687 FtsX-like permease family 199 292 3.3E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CXR48_RS13850 275076c702d6c54868c3552629cf8156 357 Gene3D G3DSA:3.40.630.10 167 355 7.5E-39 T 29-03-2018 CXR48_RS13850 275076c702d6c54868c3552629cf8156 357 Pfam PF05343 M42 glutamyl aminopeptidase 46 337 9.1E-112 T 29-03-2018 IPR008007 Peptidase M42 CXR48_RS13850 275076c702d6c54868c3552629cf8156 357 Gene3D G3DSA:2.40.30.40 70 161 4.1E-32 T 29-03-2018 IPR023367 Peptidase M42, domain 2 CXR48_RS13850 275076c702d6c54868c3552629cf8156 357 SUPERFAMILY SSF101821 71 180 2.14E-31 T 29-03-2018 CXR48_RS13850 275076c702d6c54868c3552629cf8156 357 SUPERFAMILY SSF53187 172 351 6.05E-69 T 29-03-2018 CXR48_RS13850 275076c702d6c54868c3552629cf8156 357 SUPERFAMILY SSF53187 5 81 6.05E-69 T 29-03-2018 CXR48_RS13850 275076c702d6c54868c3552629cf8156 357 PIRSF PIRSF001123 2 356 4.1E-145 T 29-03-2018 IPR008007 Peptidase M42 CXR48_RS07065 15e1138fdeb4bba737382c963df97d3d 173 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 9 162 1.2E-23 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CXR48_RS07065 15e1138fdeb4bba737382c963df97d3d 173 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 9 138 5.4E-26 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CXR48_RS07065 15e1138fdeb4bba737382c963df97d3d 173 Gene3D G3DSA:3.40.50.300 7 172 1.7E-18 T 29-03-2018 CXR48_RS07065 15e1138fdeb4bba737382c963df97d3d 173 SUPERFAMILY SSF52540 8 161 7.5E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS09550 586c8c7c500dd70e41598e2872dd82a9 627 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 18 618 1.5E-112 T 29-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CXR48_RS09550 586c8c7c500dd70e41598e2872dd82a9 627 ProSitePatterns PS01074 Terpene synthases signature. 476 490 - T 29-03-2018 IPR002365 Terpene synthase, conserved site GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CXR48_RS09550 586c8c7c500dd70e41598e2872dd82a9 627 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 308 617 1.9E-92 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CXR48_RS09550 586c8c7c500dd70e41598e2872dd82a9 627 Gene3D G3DSA:1.50.10.20 291 627 1.2E-88 T 29-03-2018 CXR48_RS09550 586c8c7c500dd70e41598e2872dd82a9 627 Gene3D G3DSA:1.50.10.20 33 290 1.6E-42 T 29-03-2018 CXR48_RS09550 586c8c7c500dd70e41598e2872dd82a9 627 SUPERFAMILY SSF48239 35 299 4.49E-47 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CXR48_RS09550 586c8c7c500dd70e41598e2872dd82a9 627 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 17 295 1.9E-62 T 29-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CXR48_RS09550 586c8c7c500dd70e41598e2872dd82a9 627 SUPERFAMILY SSF48239 305 619 2.12E-91 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CXR48_RS04390 f119a18cc26bfaa5ea5026da8f95dfff 311 Gene3D G3DSA:3.20.20.140 3 311 8.8E-45 T 29-03-2018 CXR48_RS04390 f119a18cc26bfaa5ea5026da8f95dfff 311 SUPERFAMILY SSF51556 10 302 9.19E-44 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS04390 f119a18cc26bfaa5ea5026da8f95dfff 311 Pfam PF04909 Amidohydrolase 66 301 2.9E-34 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CXR48_RS16795 b9264864d028d1aefe9dbf26e5a36ff0 305 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 83 224 2.3E-48 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CXR48_RS16795 b9264864d028d1aefe9dbf26e5a36ff0 305 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 82 225 6.1E-54 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CXR48_RS16505 4e7b3411725dd96820dba7df6406ecbd 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 58 4.0E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS16505 4e7b3411725dd96820dba7df6406ecbd 191 SUPERFAMILY SSF46689 7 73 1.18E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS16505 4e7b3411725dd96820dba7df6406ecbd 191 Gene3D G3DSA:1.10.357.10 61 183 1.1E-14 T 29-03-2018 CXR48_RS16505 4e7b3411725dd96820dba7df6406ecbd 191 Gene3D G3DSA:1.10.10.60 2 60 1.2E-11 T 29-03-2018 CXR48_RS16505 4e7b3411725dd96820dba7df6406ecbd 191 SUPERFAMILY SSF48498 79 183 1.61E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS03550 b13b38e9b6a5ef309c576f950526e7a0 170 Pfam PF01047 MarR family 53 112 3.6E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS03550 b13b38e9b6a5ef309c576f950526e7a0 170 Gene3D G3DSA:1.10.10.10 22 161 3.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03550 b13b38e9b6a5ef309c576f950526e7a0 170 SMART SM00347 46 148 6.9E-28 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS03550 b13b38e9b6a5ef309c576f950526e7a0 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 2.6E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS03550 b13b38e9b6a5ef309c576f950526e7a0 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 2.6E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS03550 b13b38e9b6a5ef309c576f950526e7a0 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 2.6E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS03550 b13b38e9b6a5ef309c576f950526e7a0 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 2.6E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS03550 b13b38e9b6a5ef309c576f950526e7a0 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CXR48_RS03550 b13b38e9b6a5ef309c576f950526e7a0 170 SUPERFAMILY SSF46785 22 160 7.86E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11205 3f77c87fc20e74a1bd7490ffea0aaea8 387 SUPERFAMILY SSF89550 2 242 6.87E-11 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CXR48_RS11205 3f77c87fc20e74a1bd7490ffea0aaea8 387 Pfam PF13263 PHP-associated 195 237 8.0E-5 T 29-03-2018 CXR48_RS11205 3f77c87fc20e74a1bd7490ffea0aaea8 387 Gene3D G3DSA:3.20.20.140 1 246 1.5E-11 T 29-03-2018 CXR48_RS11205 3f77c87fc20e74a1bd7490ffea0aaea8 387 Gene3D G3DSA:1.10.150.20 317 369 1.9E-7 T 29-03-2018 CXR48_RS11205 3f77c87fc20e74a1bd7490ffea0aaea8 387 SUPERFAMILY SSF47781 310 368 1.22E-7 T 29-03-2018 IPR010994 RuvA domain 2-like CXR48_RS11205 3f77c87fc20e74a1bd7490ffea0aaea8 387 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 27 385 3.0E-112 T 29-03-2018 IPR005287 Conserved hypothetical protein CHP00375 CXR48_RS04195 d63860499a991e840a60ad6735d33d01 88 Pfam PF14182 YgaB-like protein 3 78 1.1E-32 T 29-03-2018 IPR025572 YgaB-like protein CXR48_RS15985 54022fdeca686c7d29eef9636fcf3066 418 Gene3D G3DSA:3.90.1150.10 293 418 1.2E-9 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS15985 54022fdeca686c7d29eef9636fcf3066 418 Gene3D G3DSA:3.40.640.10 24 264 8.9E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS15985 54022fdeca686c7d29eef9636fcf3066 418 SUPERFAMILY SSF53383 55 222 3.85E-47 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS15985 54022fdeca686c7d29eef9636fcf3066 418 SUPERFAMILY SSF53383 268 412 3.85E-47 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS15985 54022fdeca686c7d29eef9636fcf3066 418 PIRSF PIRSF000390 39 415 1.2E-37 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CXR48_RS15985 54022fdeca686c7d29eef9636fcf3066 418 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 57 407 9.8E-41 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CXR48_RS01155 a9cd54f87949e474cd1fb1178c76d112 385 SUPERFAMILY SSF55874 262 380 8.12E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS01155 a9cd54f87949e474cd1fb1178c76d112 385 Pfam PF07730 Histidine kinase 189 254 8.0E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CXR48_RS01155 a9cd54f87949e474cd1fb1178c76d112 385 Gene3D G3DSA:3.30.565.10 257 383 1.0E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS01825 5ce223157c6df66dcbd7110c0689d766 234 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 25 122 1.3E-29 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CXR48_RS01825 5ce223157c6df66dcbd7110c0689d766 234 Gene3D G3DSA:1.10.3720.10 20 231 3.7E-41 T 29-03-2018 CXR48_RS01825 5ce223157c6df66dcbd7110c0689d766 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 229 2.3E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS01825 5ce223157c6df66dcbd7110c0689d766 234 SUPERFAMILY SSF161098 25 230 1.18E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS08920 b2606d2142e0770d46096316139906b3 142 ProDom PD086666 YNEK BH2332 11 141 6.0E-57 T 29-03-2018 IPR020203 Uncharacterised protein family, YneK CXR48_RS08920 b2606d2142e0770d46096316139906b3 142 Pfam PF11084 Protein of unknown function (DUF2621) 3 141 2.0E-73 T 29-03-2018 IPR020203 Uncharacterised protein family, YneK CXR48_RS17785 180c9c167341d2e89de92cf59268d737 184 Pfam PF08006 Protein of unknown function (DUF1700) 1 174 4.5E-37 T 29-03-2018 IPR012963 Protein of unknown function DUF1700 CXR48_RS04110 b2d96235fed5635d847eb02600facae3 263 Gene3D G3DSA:1.10.10.10 43 107 1.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04110 b2d96235fed5635d847eb02600facae3 263 Hamap MF_01114 Regulatory protein RecX [recX]. 42 209 17.711 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CXR48_RS04110 b2d96235fed5635d847eb02600facae3 263 Pfam PF02631 RecX family 84 206 5.3E-29 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CXR48_RS04110 b2d96235fed5635d847eb02600facae3 263 Gene3D G3DSA:1.10.10.10 109 152 1.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04110 b2d96235fed5635d847eb02600facae3 263 Gene3D G3DSA:1.10.10.10 215 263 3.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04110 b2d96235fed5635d847eb02600facae3 263 Gene3D G3DSA:1.10.10.10 154 206 2.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10035 41820daef6d58c5ac55f3ca957474671 161 PRINTS PR00070 Dihydrofolate reductase signature 27 35 1.6E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CXR48_RS10035 41820daef6d58c5ac55f3ca957474671 161 PRINTS PR00070 Dihydrofolate reductase signature 13 23 1.6E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CXR48_RS10035 41820daef6d58c5ac55f3ca957474671 161 PRINTS PR00070 Dihydrofolate reductase signature 40 51 1.6E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CXR48_RS10035 41820daef6d58c5ac55f3ca957474671 161 PRINTS PR00070 Dihydrofolate reductase signature 91 105 1.6E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CXR48_RS10035 41820daef6d58c5ac55f3ca957474671 161 Pfam PF00186 Dihydrofolate reductase 1 159 7.4E-64 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CXR48_RS10035 41820daef6d58c5ac55f3ca957474671 161 Gene3D G3DSA:3.40.430.10 1 161 3.1E-59 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CXR48_RS10035 41820daef6d58c5ac55f3ca957474671 161 PIRSF PIRSF000194 1 161 1.8E-63 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CXR48_RS10035 41820daef6d58c5ac55f3ca957474671 161 SUPERFAMILY SSF53597 1 160 1.31E-61 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CXR48_RS10035 41820daef6d58c5ac55f3ca957474671 161 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CXR48_RS14650 37ceae63aa51f05b4c8b48c1f506ab8c 205 Gene3D G3DSA:3.30.420.10 3 187 4.9E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS14650 37ceae63aa51f05b4c8b48c1f506ab8c 205 SMART SM00479 5 182 2.2E-34 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CXR48_RS14650 37ceae63aa51f05b4c8b48c1f506ab8c 205 SUPERFAMILY SSF53098 6 178 1.16E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS14650 37ceae63aa51f05b4c8b48c1f506ab8c 205 Pfam PF00929 Exonuclease 7 173 6.9E-29 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 SMART SM00421 156 213 2.5E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 Gene3D G3DSA:1.10.10.10 133 217 8.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 SUPERFAMILY SSF46894 152 215 3.2E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 211 1.8E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 SMART SM00448 1 114 2.3E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 Gene3D G3DSA:3.40.50.2300 1 132 2.8E-39 T 29-03-2018 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 3.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 3.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 3.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 Pfam PF00072 Response regulator receiver domain 3 114 1.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS01160 551271c3d6d9670e12a192d11a80541d 217 SUPERFAMILY SSF52172 1 128 7.68E-36 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS04555 2caca6a44d99533dcad57a2f3a3e56a5 463 SUPERFAMILY SSF118215 30 441 2.35E-90 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS04555 2caca6a44d99533dcad57a2f3a3e56a5 463 PRINTS PR00173 Glutamate-aspartate symporter signature 396 416 2.4E-20 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS04555 2caca6a44d99533dcad57a2f3a3e56a5 463 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 2.4E-20 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS04555 2caca6a44d99533dcad57a2f3a3e56a5 463 PRINTS PR00173 Glutamate-aspartate symporter signature 28 48 2.4E-20 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS04555 2caca6a44d99533dcad57a2f3a3e56a5 463 PRINTS PR00173 Glutamate-aspartate symporter signature 182 204 2.4E-20 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS04555 2caca6a44d99533dcad57a2f3a3e56a5 463 PRINTS PR00173 Glutamate-aspartate symporter signature 369 388 2.4E-20 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS04555 2caca6a44d99533dcad57a2f3a3e56a5 463 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 2.4E-20 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS04555 2caca6a44d99533dcad57a2f3a3e56a5 463 Gene3D G3DSA:1.10.3860.10 19 449 8.5E-86 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS04555 2caca6a44d99533dcad57a2f3a3e56a5 463 Pfam PF00375 Sodium:dicarboxylate symporter family 32 441 1.6E-97 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS13490 5f04394b028f7126c8073f908b7b2b82 371 Pfam PF01594 AI-2E family transporter 22 356 1.2E-71 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CXR48_RS13490 5f04394b028f7126c8073f908b7b2b82 371 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 359 9.6E-112 T 29-03-2018 IPR014227 Sporulation integral membrane protein YtvI CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 287 7.5E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 Gene3D G3DSA:3.50.50.60 157 312 2.3E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 3.1E-8 T 29-03-2018 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.1E-8 T 29-03-2018 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 3.1E-8 T 29-03-2018 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 224 240 3.1E-8 T 29-03-2018 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 3.1E-8 T 29-03-2018 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 Gene3D G3DSA:3.50.50.60 8 102 4.7E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 4.6E-7 T 29-03-2018 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.6E-7 T 29-03-2018 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 273 4.6E-7 T 29-03-2018 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 225 239 4.6E-7 T 29-03-2018 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 SUPERFAMILY SSF51905 1 307 3.04E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS15040 dccb008778b65f8b3efe6f1269c496a5 355 Gene3D G3DSA:3.50.50.60 109 156 0.0042 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS09720 fd23b476e9125afcf41dc511ff868fc9 84 ProDom PD710533 YODI TRANSMEMBRANE MEMBRANE 2 84 4.0E-12 T 29-03-2018 CXR48_RS02005 22773eeeff5b45e97e78180f8e5d63c2 95 SUPERFAMILY SSF54909 1 87 2.61E-27 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS02005 22773eeeff5b45e97e78180f8e5d63c2 95 Gene3D G3DSA:3.30.70.100 1 90 1.7E-23 T 29-03-2018 CXR48_RS02005 22773eeeff5b45e97e78180f8e5d63c2 95 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 3.4E-20 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 568 770 2.4E-100 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 Gene3D G3DSA:1.10.8.60 490 582 2.0E-34 T 29-03-2018 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 SUPERFAMILY SSF88697 9 198 6.46E-45 T 29-03-2018 IPR015947 PUA-like domain CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 701 720 1.5E-53 T 29-03-2018 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 724 742 1.5E-53 T 29-03-2018 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 671 690 1.5E-53 T 29-03-2018 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 593 609 1.5E-53 T 29-03-2018 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 354 373 1.5E-53 T 29-03-2018 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 PIRSF PIRSF001174 1 773 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 Gene3D G3DSA:3.30.230.10 584 770 3.1E-69 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 SUPERFAMILY SSF54211 593 768 2.84E-57 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 Hamap MF_01973 Lon protease [lon]. 9 770 73.525 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 Gene3D G3DSA:1.10.4060.10 120 209 4.2E-29 T 29-03-2018 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 674 682 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 Gene3D G3DSA:2.30.130.40 1 116 2.9E-25 T 29-03-2018 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 SUPERFAMILY SSF52540 308 586 1.74E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 SMART SM00464 8 200 3.0E-73 T 29-03-2018 IPR003111 Lon, substrate-binding domain CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 Gene3D G3DSA:3.40.50.300 311 489 1.1E-32 T 29-03-2018 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 9 196 6.5E-39 T 29-03-2018 IPR003111 Lon, substrate-binding domain CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 487 7.1E-24 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 TIGRFAM TIGR00763 lon: endopeptidase La 10 769 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CXR48_RS13000 0b51c7262a2babaf642d90c4a0077a62 774 SMART SM00382 346 491 7.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS13160 430cfadfbaff77b9c14d8148c07194ac 496 SUPERFAMILY SSF51011 357 491 6.83E-31 T 29-03-2018 CXR48_RS13160 430cfadfbaff77b9c14d8148c07194ac 496 SMART SM00813 294 485 7.1E-82 T 29-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CXR48_RS13160 430cfadfbaff77b9c14d8148c07194ac 496 Gene3D G3DSA:3.20.20.80 18 367 1.8E-106 T 29-03-2018 CXR48_RS13160 430cfadfbaff77b9c14d8148c07194ac 496 SUPERFAMILY SSF51445 17 376 5.66E-98 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS13160 430cfadfbaff77b9c14d8148c07194ac 496 Gene3D G3DSA:2.60.40.1180 368 494 7.4E-29 T 29-03-2018 CXR48_RS13160 430cfadfbaff77b9c14d8148c07194ac 496 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 294 484 6.9E-43 T 29-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CXR48_RS11540 d9b48b97016629bcbb0781940a7a05a0 297 Pfam PF01515 Phosphate acetyl/butaryl transferase 74 291 1.2E-45 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CXR48_RS11540 d9b48b97016629bcbb0781940a7a05a0 297 PIRSF PIRSF000428 1 297 1.1E-80 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CXR48_RS11540 d9b48b97016629bcbb0781940a7a05a0 297 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 4 294 9.7E-127 T 29-03-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 CXR48_RS11540 d9b48b97016629bcbb0781940a7a05a0 297 Gene3D G3DSA:3.40.50.10750 112 266 1.2E-36 T 29-03-2018 CXR48_RS11540 d9b48b97016629bcbb0781940a7a05a0 297 SUPERFAMILY SSF53659 2 294 1.39E-57 T 29-03-2018 CXR48_RS14245 3b49d1a458cead51e9918952a44c07c4 272 Gene3D G3DSA:1.10.12.10 212 260 2.3E-14 T 29-03-2018 IPR014748 Crontonase, C-terminal CXR48_RS14245 3b49d1a458cead51e9918952a44c07c4 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 267 1.8E-91 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CXR48_RS14245 3b49d1a458cead51e9918952a44c07c4 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.684 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CXR48_RS14245 3b49d1a458cead51e9918952a44c07c4 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 4.7E-131 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CXR48_RS14245 3b49d1a458cead51e9918952a44c07c4 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CXR48_RS14245 3b49d1a458cead51e9918952a44c07c4 272 Gene3D G3DSA:3.90.226.10 1 211 4.2E-63 T 29-03-2018 CXR48_RS14245 3b49d1a458cead51e9918952a44c07c4 272 SUPERFAMILY SSF52096 8 267 2.56E-78 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS17875 7c5aafe4a8e9ff583401bb8ee0bf4857 515 SUPERFAMILY SSF53720 4 511 1.31E-158 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS17875 7c5aafe4a8e9ff583401bb8ee0bf4857 515 Gene3D G3DSA:3.40.605.10 23 301 3.2E-86 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS17875 7c5aafe4a8e9ff583401bb8ee0bf4857 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS17875 7c5aafe4a8e9ff583401bb8ee0bf4857 515 Pfam PF00171 Aldehyde dehydrogenase family 49 510 1.2E-159 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS17875 7c5aafe4a8e9ff583401bb8ee0bf4857 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 514 1.5E-259 T 29-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CXR48_RS17875 7c5aafe4a8e9ff583401bb8ee0bf4857 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 66.473 T 29-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CXR48_RS17875 7c5aafe4a8e9ff583401bb8ee0bf4857 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS17875 7c5aafe4a8e9ff583401bb8ee0bf4857 515 Gene3D G3DSA:3.40.309.10 302 490 5.1E-64 T 29-03-2018 CXR48_RS07270 a57404cf26615024f818ad984bd6bf5e 325 SUPERFAMILY SSF52518 2 204 5.65E-65 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS07270 a57404cf26615024f818ad984bd6bf5e 325 Gene3D G3DSA:3.40.50.970 1 194 1.6E-61 T 29-03-2018 CXR48_RS07270 a57404cf26615024f818ad984bd6bf5e 325 Pfam PF02780 Transketolase, C-terminal domain 194 313 2.8E-39 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CXR48_RS07270 a57404cf26615024f818ad984bd6bf5e 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 3.7E-39 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS07270 a57404cf26615024f818ad984bd6bf5e 325 SMART SM00861 4 179 8.7E-61 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS07270 a57404cf26615024f818ad984bd6bf5e 325 SUPERFAMILY SSF52922 188 325 1.7E-41 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS07270 a57404cf26615024f818ad984bd6bf5e 325 Gene3D G3DSA:3.40.50.920 195 324 5.7E-34 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 190 209 2.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 129 2.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 178 2.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 51 280 2.1E-60 T 29-03-2018 CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 228 3.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 43 60 3.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 180 3.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 129 3.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 3.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 245 265 3.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 177 205 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 SUPERFAMILY SSF51735 40 282 1.19E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS05175 81ad4ffcfea2da1bd073e2304ad9fc91 285 Gene3D G3DSA:3.40.50.720 1 284 1.3E-77 T 29-03-2018 CXR48_RS01540 1cc3431feacba704d84b4a7b4668ec80 331 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 328 1.7E-116 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CXR48_RS01540 1cc3431feacba704d84b4a7b4668ec80 331 Pfam PF00296 Luciferase-like monooxygenase 16 299 3.2E-30 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS01540 1cc3431feacba704d84b4a7b4668ec80 331 SUPERFAMILY SSF51679 2 328 2.12E-70 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS01540 1cc3431feacba704d84b4a7b4668ec80 331 Gene3D G3DSA:3.20.20.30 2 330 4.0E-65 T 29-03-2018 CXR48_RS16735 66da82b3afe23545f45185d27a3ede52 358 Pfam PF00953 Glycosyl transferase family 4 78 233 1.7E-41 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CXR48_RS16735 66da82b3afe23545f45185d27a3ede52 358 ProSitePatterns PS01348 MraY family signature 2. 153 164 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CXR48_RS18075 260113ceca66129c8f5eeda53aafb663 204 Gene3D G3DSA:1.20.120.80 17 202 1.1E-49 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18075 260113ceca66129c8f5eeda53aafb663 204 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 14 201 1.3E-90 T 29-03-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 CXR48_RS18075 260113ceca66129c8f5eeda53aafb663 204 Pfam PF00510 Cytochrome c oxidase subunit III 25 200 1.3E-14 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS18075 260113ceca66129c8f5eeda53aafb663 204 SUPERFAMILY SSF81452 21 200 1.7E-52 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 Pfam PF00206 Lyase 7 286 6.0E-84 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 1.7E-10 T 29-03-2018 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 1.7E-10 T 29-03-2018 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 1.7E-10 T 29-03-2018 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 1.7E-10 T 29-03-2018 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 Gene3D G3DSA:1.10.40.30 349 428 7.9E-26 T 29-03-2018 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 1.3E-185 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 Gene3D G3DSA:1.10.275.10 2 92 2.9E-25 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 SMART SM00998 349 429 1.1E-39 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 2.1E-24 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 3.9E-27 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 3.9E-27 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 3.9E-27 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 3.9E-27 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 SUPERFAMILY SSF48557 3 427 1.88E-142 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CXR48_RS03275 ab6f24466808f2aa5d042f4a1375ea4d 430 Gene3D G3DSA:1.20.200.10 93 348 1.2E-81 T 29-03-2018 CXR48_RS07780 0693bce76f7c71bba6105a035859bd0e 261 Gene3D G3DSA:3.40.50.1400 117 229 1.2E-17 T 29-03-2018 CXR48_RS07780 0693bce76f7c71bba6105a035859bd0e 261 Gene3D G3DSA:3.40.50.1400 1 116 5.8E-24 T 29-03-2018 CXR48_RS07780 0693bce76f7c71bba6105a035859bd0e 261 Pfam PF01903 CbiX 134 234 3.6E-19 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CXR48_RS07780 0693bce76f7c71bba6105a035859bd0e 261 Pfam PF01903 CbiX 10 114 8.8E-27 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CXR48_RS07780 0693bce76f7c71bba6105a035859bd0e 261 SUPERFAMILY SSF53800 2 242 2.62E-47 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 Pfam PF00117 Glutamine amidotransferase class-I 11 189 5.6E-46 T 29-03-2018 IPR017926 Glutamine amidotransferase CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 Gene3D G3DSA:3.40.50.620 225 381 3.0E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 513 55.563 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 SUPERFAMILY SSF52317 7 228 1.25E-60 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 4.9E-8 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 4.9E-8 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 4.9E-8 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 Gene3D G3DSA:3.30.300.10 389 513 2.2E-54 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 Pfam PF02540 NAD synthase 214 284 7.6E-6 T 29-03-2018 IPR022310 NAD/GMP synthase CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 2.7E-6 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 2.7E-6 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 2.7E-6 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 SUPERFAMILY SSF54810 393 513 2.35E-51 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 Pfam PF00958 GMP synthase C terminal domain 421 512 2.3E-44 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 195 1.2E-86 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 513 3.5E-160 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 PRINTS PR00097 Anthranilate synthase component II signature 80 91 4.3E-6 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 PRINTS PR00097 Anthranilate synthase component II signature 168 181 4.3E-6 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 PRINTS PR00097 Anthranilate synthase component II signature 53 62 4.3E-6 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 SUPERFAMILY SSF52402 188 406 6.17E-62 T 29-03-2018 CXR48_RS03225 2d002ddb4df9cbf1a5f5cd85025b6fef 513 Gene3D G3DSA:3.40.50.880 4 224 6.3E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS09040 7c37f64337dadbd01a401508227b2843 423 Pfam PF07690 Major Facilitator Superfamily 13 369 4.9E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS09040 7c37f64337dadbd01a401508227b2843 423 Gene3D G3DSA:1.20.1250.20 1 198 1.1E-39 T 29-03-2018 CXR48_RS09040 7c37f64337dadbd01a401508227b2843 423 SUPERFAMILY SSF103473 3 407 9.55E-80 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS09040 7c37f64337dadbd01a401508227b2843 423 PIRSF PIRSF002808 1 420 4.0E-38 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CXR48_RS09040 7c37f64337dadbd01a401508227b2843 423 Gene3D G3DSA:1.20.1250.20 203 419 9.5E-27 T 29-03-2018 CXR48_RS05320 f3c6cd1da2dcd556f397d5296435f5a6 78 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 50 2.0E-19 T 29-03-2018 IPR024255 Spore germination GerPB CXR48_RS05320 f3c6cd1da2dcd556f397d5296435f5a6 78 Pfam PF10803 Spore germination GerPB 1 51 4.2E-29 T 29-03-2018 IPR024255 Spore germination GerPB CXR48_RS08240 fc5fb7de652d19862276a2ee52cff9f0 185 Gene3D G3DSA:1.10.132.20 75 184 9.4E-39 T 29-03-2018 CXR48_RS08240 fc5fb7de652d19862276a2ee52cff9f0 185 Gene3D G3DSA:1.10.132.20 3 74 9.2E-10 T 29-03-2018 CXR48_RS08240 fc5fb7de652d19862276a2ee52cff9f0 185 SUPERFAMILY SSF55194 3 185 1.3E-72 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CXR48_RS08240 fc5fb7de652d19862276a2ee52cff9f0 185 Pfam PF01765 Ribosome recycling factor 21 183 1.6E-65 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CXR48_RS08240 fc5fb7de652d19862276a2ee52cff9f0 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.958 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CXR48_RS08240 fc5fb7de652d19862276a2ee52cff9f0 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.2E-80 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CXR48_RS09850 7cf9d3efcb0f618cd673772acba8b4a5 141 Pfam PF02719 Polysaccharide biosynthesis protein 18 140 7.4E-43 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CXR48_RS09850 7cf9d3efcb0f618cd673772acba8b4a5 141 Gene3D G3DSA:3.40.50.720 12 141 5.4E-31 T 29-03-2018 CXR48_RS09850 7cf9d3efcb0f618cd673772acba8b4a5 141 SUPERFAMILY SSF51735 15 140 1.94E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS04535 0c909e4ff02a9e4764d118accb5fa6e1 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CXR48_RS04535 0c909e4ff02a9e4764d118accb5fa6e1 66 SMART SM00357 3 66 1.3E-30 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CXR48_RS04535 0c909e4ff02a9e4764d118accb5fa6e1 66 PRINTS PR00050 Cold shock protein signature 24 33 5.3E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS04535 0c909e4ff02a9e4764d118accb5fa6e1 66 PRINTS PR00050 Cold shock protein signature 39 57 5.3E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS04535 0c909e4ff02a9e4764d118accb5fa6e1 66 PRINTS PR00050 Cold shock protein signature 4 19 5.3E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS04535 0c909e4ff02a9e4764d118accb5fa6e1 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.0E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS04535 0c909e4ff02a9e4764d118accb5fa6e1 66 Gene3D G3DSA:2.40.50.140 1 66 1.8E-28 T 29-03-2018 CXR48_RS04535 0c909e4ff02a9e4764d118accb5fa6e1 66 PIRSF PIRSF002599 1 66 4.3E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CXR48_RS04535 0c909e4ff02a9e4764d118accb5fa6e1 66 SUPERFAMILY SSF50249 1 64 1.41E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 Pfam PF00571 CBS domain 342 394 0.0011 T 29-03-2018 IPR000644 CBS domain CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 SMART SM00382 58 247 3.4E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 SMART SM00116 347 394 0.01 T 29-03-2018 IPR000644 CBS domain CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 SMART SM00116 287 335 6.9E-4 T 29-03-2018 IPR000644 CBS domain CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 Gene3D G3DSA:3.10.580.10 279 400 6.2E-15 T 29-03-2018 CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 SUPERFAMILY SSF52540 40 275 9.58E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 SUPERFAMILY SSF54631 279 395 9.1E-18 T 29-03-2018 CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 41 396 1.4E-175 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 Gene3D G3DSA:3.40.50.300 6 278 7.0E-75 T 29-03-2018 CXR48_RS01580 f6a12964185785c8d1457dcb27bb8df4 418 Pfam PF00005 ABC transporter 50 197 1.5E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS07310 8a14b8369590d5be876f71afde657b90 210 Hamap MF_01851 UPF0637 protein . 5 205 38.483 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 CXR48_RS07310 8a14b8369590d5be876f71afde657b90 210 PIRSF PIRSF021332 1 209 1.9E-89 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 CXR48_RS07310 8a14b8369590d5be876f71afde657b90 210 Pfam PF06335 Protein of unknown function (DUF1054) 6 203 4.0E-85 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 CXR48_RS07310 8a14b8369590d5be876f71afde657b90 210 SUPERFAMILY SSF142913 3 208 6.28E-85 T 29-03-2018 CXR48_RS10115 3010d918e885c1754663cc817058d87f 226 Pfam PF02592 Putative vitamin uptake transporter 57 217 5.7E-46 T 29-03-2018 IPR003744 Queuosine precursor transporter CXR48_RS10115 3010d918e885c1754663cc817058d87f 226 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 222 8.4E-72 T 29-03-2018 IPR003744 Queuosine precursor transporter CXR48_RS16510 07226a8d370d978885e2588b7b3e970a 1289 Pfam PF00932 Lamin Tail Domain 152 283 5.4E-8 T 29-03-2018 IPR001322 Lamin Tail Domain CXR48_RS16510 07226a8d370d978885e2588b7b3e970a 1289 Gene3D G3DSA:3.60.21.10 915 1204 1.1E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS16510 07226a8d370d978885e2588b7b3e970a 1289 SUPERFAMILY SSF56300 918 1118 1.54E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS16510 07226a8d370d978885e2588b7b3e970a 1289 Gene3D G3DSA:2.60.40.10 446 733 1.2E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS16510 07226a8d370d978885e2588b7b3e970a 1289 Pfam PF00149 Calcineurin-like phosphoesterase 921 1117 5.4E-14 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CXR48_RS16510 07226a8d370d978885e2588b7b3e970a 1289 PIRSF PIRSF036444 4 1289 0.0 T 29-03-2018 IPR011401 Phosphoesterase, YvnB CXR48_RS16510 07226a8d370d978885e2588b7b3e970a 1289 Gene3D G3DSA:2.60.40.1260 124 290 5.6E-15 T 29-03-2018 IPR001322 Lamin Tail Domain CXR48_RS12445 36f8c7846f2d0524acfa1f29d40116ae 241 Gene3D G3DSA:3.40.50.10490 71 241 2.4E-24 T 29-03-2018 CXR48_RS12445 36f8c7846f2d0524acfa1f29d40116ae 241 Pfam PF01380 SIS domain 109 229 3.1E-15 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CXR48_RS12445 36f8c7846f2d0524acfa1f29d40116ae 241 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 69 2.9E-15 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CXR48_RS12445 36f8c7846f2d0524acfa1f29d40116ae 241 SUPERFAMILY SSF53697 77 240 7.02E-30 T 29-03-2018 CXR48_RS12445 36f8c7846f2d0524acfa1f29d40116ae 241 SUPERFAMILY SSF46689 5 70 6.81E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS12445 36f8c7846f2d0524acfa1f29d40116ae 241 Gene3D G3DSA:1.10.10.10 4 70 2.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02325 0f5bafb39ce9d316f8225f6f1afb8983 223 PIRSF PIRSF006171 1 223 3.4E-80 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CXR48_RS02325 0f5bafb39ce9d316f8225f6f1afb8983 223 Pfam PF04703 FaeA-like protein 161 204 2.3E-6 T 29-03-2018 IPR006793 FaeA-like protein GO:0006355|GO:0009289 CXR48_RS02325 0f5bafb39ce9d316f8225f6f1afb8983 223 SUPERFAMILY SSF46785 162 207 2.47E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02325 0f5bafb39ce9d316f8225f6f1afb8983 223 Gene3D G3DSA:3.40.50.2300 2 128 1.9E-32 T 29-03-2018 CXR48_RS02325 0f5bafb39ce9d316f8225f6f1afb8983 223 Pfam PF00072 Response regulator receiver domain 5 116 1.9E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS02325 0f5bafb39ce9d316f8225f6f1afb8983 223 Gene3D G3DSA:1.10.10.10 129 220 1.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02325 0f5bafb39ce9d316f8225f6f1afb8983 223 SMART SM00448 3 116 1.2E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS02325 0f5bafb39ce9d316f8225f6f1afb8983 223 ProDom PD007170 TRANSCRIPTION REGULATORY REGULATION FIMBRIA FIMBRIAL PLASMID ACTIVATOR PAPI OPERON PEFI 161 204 9.0E-4 T 29-03-2018 IPR006793 FaeA-like protein GO:0006355|GO:0009289 CXR48_RS02325 0f5bafb39ce9d316f8225f6f1afb8983 223 SUPERFAMILY SSF52172 3 168 7.68E-35 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS18535 218201072b86118717f80106004347f0 2343 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 56 275 7.0E-92 T 29-03-2018 CXR48_RS18535 218201072b86118717f80106004347f0 2343 Pfam PF05593 RHS Repeat 1080 1106 1.2E-4 T 29-03-2018 IPR031325 RHS repeat CXR48_RS18535 218201072b86118717f80106004347f0 2343 Pfam PF05593 RHS Repeat 2085 2116 1.0E-6 T 29-03-2018 IPR031325 RHS repeat CXR48_RS18535 218201072b86118717f80106004347f0 2343 Pfam PF05593 RHS Repeat 1639 1675 9.4E-5 T 29-03-2018 IPR031325 RHS repeat CXR48_RS18535 218201072b86118717f80106004347f0 2343 Pfam PF05593 RHS Repeat 1035 1068 3.6E-8 T 29-03-2018 IPR031325 RHS repeat CXR48_RS18535 218201072b86118717f80106004347f0 2343 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2107 2190 1.8E-20 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CXR48_RS18535 218201072b86118717f80106004347f0 2343 SUPERFAMILY SSF49785 1292 1434 2.98E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS18535 218201072b86118717f80106004347f0 2343 Gene3D G3DSA:2.60.40.10 620 754 1.6E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS18535 218201072b86118717f80106004347f0 2343 Gene3D G3DSA:2.60.40.10 489 619 2.4E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS18535 218201072b86118717f80106004347f0 2343 Gene3D G3DSA:2.60.40.10 755 888 4.2E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS18535 218201072b86118717f80106004347f0 2343 Gene3D G3DSA:2.60.120.260 1460 1618 2.2E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS18535 218201072b86118717f80106004347f0 2343 Gene3D G3DSA:2.60.120.260 1280 1459 1.4E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS18535 218201072b86118717f80106004347f0 2343 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1725 1755 0.0025 T 29-03-2018 IPR006530 YD repeat CXR48_RS18535 218201072b86118717f80106004347f0 2343 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1639 1674 2.9E-4 T 29-03-2018 IPR006530 YD repeat CXR48_RS18535 218201072b86118717f80106004347f0 2343 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1922 1959 3.9E-8 T 29-03-2018 IPR006530 YD repeat CXR48_RS18535 218201072b86118717f80106004347f0 2343 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1084 1106 9.3E-4 T 29-03-2018 IPR006530 YD repeat CXR48_RS18535 218201072b86118717f80106004347f0 2343 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1035 1070 4.7E-7 T 29-03-2018 IPR006530 YD repeat CXR48_RS13970 9948ef79697b38939d35946325adbf62 304 SUPERFAMILY SSF160964 23 62 5.75E-5 T 29-03-2018 CXR48_RS13970 9948ef79697b38939d35946325adbf62 304 Gene3D G3DSA:1.20.58.370 13 53 4.0E-5 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CXR48_RS13970 9948ef79697b38939d35946325adbf62 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 294 2.4E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS13970 9948ef79697b38939d35946325adbf62 304 Gene3D G3DSA:1.10.3720.10 69 300 7.1E-47 T 29-03-2018 CXR48_RS13970 9948ef79697b38939d35946325adbf62 304 SUPERFAMILY SSF161098 66 289 4.19E-62 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS08480 d8b6ad2dee79bae18e59c6e4ac446f37 392 Gene3D G3DSA:3.90.1150.10 283 392 2.9E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS08480 d8b6ad2dee79bae18e59c6e4ac446f37 392 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 22 382 6.5E-135 T 29-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 CXR48_RS08480 d8b6ad2dee79bae18e59c6e4ac446f37 392 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 237 246 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CXR48_RS08480 d8b6ad2dee79bae18e59c6e4ac446f37 392 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 8 392 2.4E-199 T 29-03-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type CXR48_RS08480 d8b6ad2dee79bae18e59c6e4ac446f37 392 SUPERFAMILY SSF53383 2 389 2.18E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS08480 d8b6ad2dee79bae18e59c6e4ac446f37 392 Pfam PF00155 Aminotransferase class I and II 41 382 1.5E-69 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS08480 d8b6ad2dee79bae18e59c6e4ac446f37 392 Gene3D G3DSA:3.40.640.10 47 282 2.5E-56 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS07785 9a60638939dd9155401fef1c7866c9d7 162 SUPERFAMILY SSF75615 106 161 1.1E-10 T 29-03-2018 CXR48_RS07785 9a60638939dd9155401fef1c7866c9d7 162 Gene3D G3DSA:3.40.50.720 1 117 7.7E-23 T 29-03-2018 CXR48_RS07785 9a60638939dd9155401fef1c7866c9d7 162 SUPERFAMILY SSF51735 1 97 1.18E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07785 9a60638939dd9155401fef1c7866c9d7 162 Pfam PF13241 Putative NAD(P)-binding 5 111 2.6E-25 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CXR48_RS07785 9a60638939dd9155401fef1c7866c9d7 162 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 2 160 5.4E-31 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CXR48_RS07785 9a60638939dd9155401fef1c7866c9d7 162 Gene3D G3DSA:3.30.160.110 118 144 2.5E-10 T 29-03-2018 CXR48_RS08045 10820815633afd0fc26bea629bad6a81 305 Pfam PF00589 Phage integrase family 113 287 7.1E-55 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CXR48_RS08045 10820815633afd0fc26bea629bad6a81 305 Gene3D G3DSA:1.10.150.130 2 113 1.4E-22 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CXR48_RS08045 10820815633afd0fc26bea629bad6a81 305 Gene3D G3DSA:1.10.443.10 114 295 1.3E-48 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CXR48_RS08045 10820815633afd0fc26bea629bad6a81 305 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 11 302 4.6E-112 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CXR48_RS08045 10820815633afd0fc26bea629bad6a81 305 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 7 301 54.574 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CXR48_RS08045 10820815633afd0fc26bea629bad6a81 305 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 92 1.7E-22 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CXR48_RS08045 10820815633afd0fc26bea629bad6a81 305 SUPERFAMILY SSF56349 8 295 2.68E-58 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CXR48_RS05920 57402728bf61ba2ca131093a61c4eafe 470 SUPERFAMILY SSF103473 10 201 1.57E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS05920 57402728bf61ba2ca131093a61c4eafe 470 SUPERFAMILY SSF103473 255 465 1.57E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS05920 57402728bf61ba2ca131093a61c4eafe 470 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 425 1.4E-89 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CXR48_RS05920 57402728bf61ba2ca131093a61c4eafe 470 Gene3D G3DSA:1.20.1250.20 4 204 5.9E-32 T 29-03-2018 CXR48_RS05920 57402728bf61ba2ca131093a61c4eafe 470 Pfam PF07690 Major Facilitator Superfamily 23 387 9.7E-49 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS05920 57402728bf61ba2ca131093a61c4eafe 470 Gene3D G3DSA:1.20.1250.20 266 469 4.1E-25 T 29-03-2018 CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 416 169.937 T 29-03-2018 IPR008135 Competence-induced protein CinA CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 Gene3D G3DSA:3.40.980.10 4 175 1.5E-44 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 267 413 2.7E-53 T 29-03-2018 IPR008136 CinA, C-terminal CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 PIRSF PIRSF006728 4 416 8.2E-167 T 29-03-2018 IPR008135 Competence-induced protein CinA CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 Gene3D G3DSA:3.90.950.20 251 416 6.9E-54 T 29-03-2018 CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 SUPERFAMILY SSF53218 6 210 4.45E-42 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 SMART SM00852 8 175 3.5E-44 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 SUPERFAMILY SSF142433 254 413 6.93E-47 T 29-03-2018 IPR008136 CinA, C-terminal CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 Pfam PF00994 Probable molybdopterin binding domain 8 172 1.5E-35 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 6 170 5.7E-40 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 5 416 9.3E-203 T 29-03-2018 IPR008135 Competence-induced protein CinA CXR48_RS08445 d6d1be7ddcf97b770d32a0597dae1805 416 Pfam PF02464 Competence-damaged protein 261 413 1.4E-50 T 29-03-2018 IPR008136 CinA, C-terminal CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 Pfam PF04539 Sigma-70 region 3 115 183 4.0E-13 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 SUPERFAMILY SSF88659 171 250 5.05E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 Pfam PF04542 Sigma-70 region 2 37 104 1.2E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 SUPERFAMILY SSF88659 109 184 1.18E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 PIRSF PIRSF000770 11 255 7.1E-36 T 29-03-2018 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 220 246 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 Gene3D G3DSA:1.10.601.10 3 105 3.1E-33 T 29-03-2018 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 235 246 2.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 220 235 2.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 203 215 2.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 85 93 2.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 61 74 2.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 Gene3D G3DSA:1.10.10.10 190 251 3.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 249 1.5E-113 T 29-03-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 Gene3D G3DSA:1.10.10.10 106 158 6.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 SUPERFAMILY SSF88946 7 105 4.97E-34 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 250 6.0E-88 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 Pfam PF04545 Sigma-70, region 4 199 247 4.1E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11120 367df27e511a8aa911d009a08f09e356 255 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 250 6.2E-37 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 SUPERFAMILY SSF51735 1583 1756 5.99E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 ProSitePatterns PS00012 Phosphopantetheine attachment site. 300 315 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 656 903 1.4E-81 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Gene3D G3DSA:3.40.47.10 647 915 8.0E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Pfam PF00550 Phosphopantetheine attachment site 276 339 2.7E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Gene3D G3DSA:1.10.1200.10 208 256 0.0015 T 29-03-2018 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Gene3D G3DSA:1.10.1200.10 257 351 1.4E-15 T 29-03-2018 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 SUPERFAMILY SSF53901 1058 1077 4.64E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 SUPERFAMILY SSF53901 655 1018 4.64E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Pfam PF14765 Polyketide synthase dehydratase 373 630 7.2E-21 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Pfam PF14765 Polyketide synthase dehydratase 1265 1550 6.6E-57 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Pfam PF14765 Polyketide synthase dehydratase 10 263 2.6E-20 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1029 1133 2.2E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 SMART SM00825 Beta-ketoacyl synthase 657 1083 3.8E-189 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Pfam PF08659 KR domain 1776 1954 3.1E-43 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1776 1956 2.9E-32 T 29-03-2018 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 SUPERFAMILY SSF51735 1769 1995 2.28E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Gene3D G3DSA:3.40.50.720 1765 2049 2.3E-37 T 29-03-2018 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 SMART SM00826 1265 1432 3.0E-18 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 911 1025 3.0E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Gene3D G3DSA:3.10.129.10 2 108 2.2E-9 T 29-03-2018 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Gene3D G3DSA:3.10.129.10 352 478 4.5E-8 T 29-03-2018 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Gene3D G3DSA:3.10.129.10 1268 1391 1.5E-16 T 29-03-2018 CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 SUPERFAMILY SSF47336 270 360 7.46E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11335 e0ea063e6e786ea7928193784a858361 2051 Gene3D G3DSA:3.40.47.10 918 1081 6.7E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 121 1.8E-25 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 SMART SM01008 18 121 5.0E-44 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 SUPERFAMILY SSF54665 3 142 1.05E-40 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 Gene3D G3DSA:3.30.365.10 452 601 5.6E-35 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 Gene3D G3DSA:3.90.1170.50 2 121 7.1E-33 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 SUPERFAMILY SSF56003 113 769 8.77E-165 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 Gene3D G3DSA:3.30.365.10 273 432 3.9E-40 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 Gene3D G3DSA:3.30.365.10 165 272 3.2E-27 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 156 704 2.3E-139 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CXR48_RS18850 87ce38e1c1575bade8caa1a87c61bc3e 776 Gene3D G3DSA:3.30.365.10 602 770 7.3E-36 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CXR48_RS17240 d12be07861637e7bbd187feb19c5af4e 454 Gene3D G3DSA:1.20.1250.20 250 453 4.7E-27 T 29-03-2018 CXR48_RS17240 d12be07861637e7bbd187feb19c5af4e 454 Pfam PF07690 Major Facilitator Superfamily 16 408 1.2E-56 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS17240 d12be07861637e7bbd187feb19c5af4e 454 Gene3D G3DSA:1.20.1250.20 2 192 1.8E-30 T 29-03-2018 CXR48_RS17240 d12be07861637e7bbd187feb19c5af4e 454 SUPERFAMILY SSF103473 246 451 2.49E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS17240 d12be07861637e7bbd187feb19c5af4e 454 SUPERFAMILY SSF103473 4 191 2.49E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 PIRSF PIRSF000850 305 395 0.61 T 29-03-2018 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 PIRSF PIRSF000850 385 477 0.16 T 29-03-2018 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 PIRSF PIRSF000850 104 278 0.08 T 29-03-2018 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 Pfam PF13396 Phospholipase_D-nuclease N-terminal 13 55 2.5E-12 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 SMART SM00155 217 244 6.1E-7 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 SMART SM00155 395 422 9.7E-7 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 Gene3D G3DSA:3.30.870.10 108 309 3.3E-38 T 29-03-2018 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 Hamap MF_01916 Cardiolipin synthase. 9 482 45.232 T 29-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 SUPERFAMILY SSF56024 269 468 2.47E-52 T 29-03-2018 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 SUPERFAMILY SSF56024 80 312 2.92E-58 T 29-03-2018 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 Gene3D G3DSA:3.30.870.10 311 476 2.8E-31 T 29-03-2018 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 7 482 1.5E-194 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 Pfam PF13091 PLD-like domain 323 449 6.8E-28 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CXR48_RS17295 ab51688c454d52fee8c5b2c3f1c5924c 482 Pfam PF13091 PLD-like domain 134 277 3.8E-15 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 SUPERFAMILY SSF53067 8 128 3.04E-31 T 29-03-2018 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 Gene3D G3DSA:3.30.420.40 7 149 5.1E-44 T 29-03-2018 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 Gene3D G3DSA:3.30.420.40 150 294 1.9E-22 T 29-03-2018 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 SUPERFAMILY SSF53067 107 315 5.41E-44 T 29-03-2018 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 7 338 63.499 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 Pfam PF00814 Glycoprotease family 30 313 1.1E-106 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 ProSitePatterns PS01016 Glycoprotease family signature. 102 122 - T 29-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 10 313 1.7E-108 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 9 320 1.6E-133 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 103 122 1.6E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 269 278 1.6E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 136 148 1.6E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 159 180 1.6E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 82 102 1.6E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03040 ab5baeb1463c9c0d034cf3ddaf33c50f 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 10 23 1.6E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS00460 e920b575c21ba63aa34606b99020e54e 285 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 27 42 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CXR48_RS00460 e920b575c21ba63aa34606b99020e54e 285 Pfam PF00809 Pterin binding enzyme 28 261 2.8E-86 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CXR48_RS00460 e920b575c21ba63aa34606b99020e54e 285 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 27 276 5.7E-100 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CXR48_RS00460 e920b575c21ba63aa34606b99020e54e 285 SUPERFAMILY SSF51717 17 278 2.75E-98 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CXR48_RS00460 e920b575c21ba63aa34606b99020e54e 285 Gene3D G3DSA:3.20.20.20 155 280 1.7E-45 T 29-03-2018 CXR48_RS00460 e920b575c21ba63aa34606b99020e54e 285 Gene3D G3DSA:3.20.20.20 24 154 1.5E-60 T 29-03-2018 CXR48_RS00460 e920b575c21ba63aa34606b99020e54e 285 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 61 74 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CXR48_RS10675 8c61e7f3f9b1e2e187453995457c9297 260 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 28 253 3.6E-82 T 29-03-2018 IPR014231 Sporulation protein YpjB CXR48_RS10675 8c61e7f3f9b1e2e187453995457c9297 260 TIGRFAM TIGR02878 spore_ypjB: sporulation protein YpjB 28 254 6.3E-88 T 29-03-2018 IPR014231 Sporulation protein YpjB CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 SUPERFAMILY SSF56059 670 924 9.55E-76 T 29-03-2018 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 SUPERFAMILY SSF52440 554 672 2.01E-45 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 426 542 2.6E-38 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Gene3D G3DSA:3.30.470.20 750 1006 8.4E-36 T 29-03-2018 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 SUPERFAMILY SSF48108 394 547 4.97E-44 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Gene3D G3DSA:3.30.470.20 119 401 3.8E-66 T 29-03-2018 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 706 720 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 SMART SM01096 420 542 7.6E-60 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 6.7E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 6.7E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 6.7E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 6.7E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 6.7E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 6.7E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 6.7E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Gene3D G3DSA:3.40.50.20 534 651 6.4E-56 T 29-03-2018 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Gene3D G3DSA:3.40.50.20 2 117 1.0E-36 T 29-03-2018 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Gene3D G3DSA:3.30.1490.20 652 748 7.1E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 957 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1018 12.366 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 SUPERFAMILY SSF52440 1 127 2.59E-47 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 833 840 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 SUPERFAMILY SSF56059 128 399 6.01E-107 T 29-03-2018 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 1.8E-82 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 670 869 2.1E-34 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS05510 8dadf795d54d5f7c5227240957f788a4 1031 Gene3D G3DSA:1.10.1030.10 411 533 4.3E-43 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS12470 a5a9e5d579d93ac60f538d8429095247 160 Pfam PF04073 Aminoacyl-tRNA editing domain 39 149 4.0E-23 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CXR48_RS12470 a5a9e5d579d93ac60f538d8429095247 160 SUPERFAMILY SSF55826 8 159 3.53E-37 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CXR48_RS12470 a5a9e5d579d93ac60f538d8429095247 160 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 8 159 3.8E-55 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CXR48_RS12470 a5a9e5d579d93ac60f538d8429095247 160 PIRSF PIRSF006181 3 160 3.0E-58 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CXR48_RS12470 a5a9e5d579d93ac60f538d8429095247 160 Gene3D G3DSA:3.90.960.10 1 160 7.0E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CXR48_RS16745 3a1a0c05538cb8b63cba9f6e1bb2a7a3 252 Pfam PF00535 Glycosyl transferase family 2 9 123 6.0E-39 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS16745 3a1a0c05538cb8b63cba9f6e1bb2a7a3 252 Gene3D G3DSA:3.90.550.10 4 250 3.4E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16745 3a1a0c05538cb8b63cba9f6e1bb2a7a3 252 SUPERFAMILY SSF53448 6 226 9.52E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 Pfam PF07729 FCD domain 95 213 9.5E-22 T 29-03-2018 IPR011711 GntR, C-terminal CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.2E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.2E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 Gene3D G3DSA:1.10.10.10 1 76 6.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 SMART SM00895 95 215 8.2E-21 T 29-03-2018 IPR011711 GntR, C-terminal CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 Gene3D G3DSA:1.20.120.530 82 228 7.0E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 SMART SM00345 15 74 1.8E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 SUPERFAMILY SSF48008 92 219 4.97E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.8E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02935 440c94e951ddbc638215bacf837e64c0 228 SUPERFAMILY SSF46785 5 109 4.84E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 SUPERFAMILY SSF109998 250 423 1.06E-41 T 29-03-2018 IPR027304 Trigger factor/SurA domain CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 8.4E-45 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 Hamap MF_00303 Trigger factor [tig]. 1 424 23.56 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 TIGRFAM TIGR00115 tig: trigger factor 12 421 1.0E-142 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 SUPERFAMILY SSF54534 89 243 2.55E-37 T 29-03-2018 CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 Gene3D G3DSA:3.30.70.1050 1 119 1.8E-38 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 3.4E-15 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 3.2E-46 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 Gene3D G3DSA:1.10.3120.10 213 399 1.2E-54 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 SUPERFAMILY SSF102735 1 128 5.36E-39 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CXR48_RS13015 30f35e6554d529abdff57bb9088c783e 424 PIRSF PIRSF003095 1 424 3.1E-137 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 660 907 4.8E-84 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 SUPERFAMILY SSF47336 644 672 1.57E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 SUPERFAMILY SSF47336 543 617 1.57E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Gene3D G3DSA:3.10.129.10 1271 1385 7.4E-9 T 29-03-2018 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Gene3D G3DSA:1.10.1200.10 546 654 9.3E-13 T 29-03-2018 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 SMART SM00825 Beta-ketoacyl synthase 662 1087 1.2E-188 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 SUPERFAMILY SSF53901 1063 1083 1.06E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 SUPERFAMILY SSF53901 657 1025 1.06E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Gene3D G3DSA:3.40.50.720 276 545 2.1E-39 T 29-03-2018 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 915 1032 1.1E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 SMART SM00826 1268 1430 3.1E-5 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Pfam PF08659 KR domain 280 458 2.1E-52 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 SUPERFAMILY SSF51735 277 497 3.81E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Pfam PF00550 Phosphopantetheine attachment site 547 611 6.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1036 1138 7.4E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 SMART SM00823 Phosphopantetheine attachment site 546 616 4.0E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 280 460 1.9E-41 T 29-03-2018 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Gene3D G3DSA:3.40.47.10 655 919 7.5E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Pfam PF14765 Polyketide synthase dehydratase 1268 1541 4.4E-49 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS07230 11f46657fc6c1fa516546c711fce9bb4 1590 Gene3D G3DSA:3.40.47.10 922 1085 4.4E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08395 2d05684b49b4c0b975e7da67d3752497 389 Gene3D G3DSA:1.20.1250.20 188 388 2.2E-28 T 29-03-2018 CXR48_RS08395 2d05684b49b4c0b975e7da67d3752497 389 Gene3D G3DSA:1.20.1250.20 1 187 1.1E-31 T 29-03-2018 CXR48_RS08395 2d05684b49b4c0b975e7da67d3752497 389 SUPERFAMILY SSF103473 3 383 1.12E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS08395 2d05684b49b4c0b975e7da67d3752497 389 Pfam PF07690 Major Facilitator Superfamily 2 285 6.9E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS08395 2d05684b49b4c0b975e7da67d3752497 389 PRINTS PR01035 Tetracycline resistance protein signature 326 349 6.8E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS08395 2d05684b49b4c0b975e7da67d3752497 389 PRINTS PR01035 Tetracycline resistance protein signature 150 170 6.8E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS08395 2d05684b49b4c0b975e7da67d3752497 389 PRINTS PR01035 Tetracycline resistance protein signature 26 45 6.8E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS11650 1af160cdaf2730f1955354dfaa476917 281 PIRSF PIRSF005578 1 267 2.9E-106 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CXR48_RS11650 1af160cdaf2730f1955354dfaa476917 281 Pfam PF01479 S4 domain 6 47 2.4E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS11650 1af160cdaf2730f1955354dfaa476917 281 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 239 1.5E-98 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CXR48_RS11650 1af160cdaf2730f1955354dfaa476917 281 Gene3D G3DSA:3.10.290.10 1 64 6.4E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS11650 1af160cdaf2730f1955354dfaa476917 281 Pfam PF01728 FtsJ-like methyltransferase 62 243 1.3E-16 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CXR48_RS11650 1af160cdaf2730f1955354dfaa476917 281 Gene3D G3DSA:3.40.50.150 65 281 1.4E-59 T 29-03-2018 CXR48_RS11650 1af160cdaf2730f1955354dfaa476917 281 SUPERFAMILY SSF55174 5 71 1.38E-11 T 29-03-2018 CXR48_RS11650 1af160cdaf2730f1955354dfaa476917 281 SMART SM00363 6 71 1.1E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS11650 1af160cdaf2730f1955354dfaa476917 281 SUPERFAMILY SSF53335 58 246 1.66E-20 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS05145 e0bc6affaaedccce846a7750776b0de3 191 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CXR48_RS05145 e0bc6affaaedccce846a7750776b0de3 191 PIRSF PIRSF000709 2 186 2.3E-9 T 29-03-2018 CXR48_RS05145 e0bc6affaaedccce846a7750776b0de3 191 Gene3D G3DSA:3.40.50.1240 1 191 6.6E-52 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CXR48_RS05145 e0bc6affaaedccce846a7750776b0de3 191 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 183 6.9E-51 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CXR48_RS05145 e0bc6affaaedccce846a7750776b0de3 191 SMART SM00855 3 146 9.1E-23 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CXR48_RS05145 e0bc6affaaedccce846a7750776b0de3 191 SUPERFAMILY SSF53254 1 189 3.14E-54 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 SUPERFAMILY SSF50677 224 410 4.29E-55 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 Gene3D G3DSA:3.40.50.620 399 604 2.0E-69 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 Pfam PF09334 tRNA synthetases class I (M) 39 170 5.7E-18 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 SUPERFAMILY SSF47323 619 803 1.37E-39 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 603 7.0E-19 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 803 23.283 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 3.8E-68 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 803 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 Gene3D G3DSA:3.40.50.620 1 229 1.6E-78 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 SUPERFAMILY SSF52374 411 625 1.38E-144 T 29-03-2018 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 SUPERFAMILY SSF52374 6 224 1.38E-144 T 29-03-2018 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 Gene3D G3DSA:3.90.740.10 230 398 4.3E-59 T 29-03-2018 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 Pfam PF08264 Anticodon-binding domain of tRNA 655 765 1.7E-19 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 2.0E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 2.0E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 2.0E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 2.0E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 2.0E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 2.0E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 2.0E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CXR48_RS13995 f3b10096e5ed97a19c58395d0246bc56 804 Gene3D G3DSA:1.10.730.10 605 740 1.4E-31 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 Gene3D G3DSA:2.160.20.10 223 318 3.7E-4 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 Gene3D G3DSA:2.160.20.10 2 222 9.4E-39 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00722 226 380 7.1E-4 T 29-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SUPERFAMILY SSF51126 420 565 1.49E-8 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SUPERFAMILY SSF51126 280 468 9.08E-15 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 Gene3D G3DSA:2.160.20.10 319 483 1.2E-14 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 Gene3D G3DSA:2.160.20.10 484 573 4.5E-5 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 Pfam PF13229 Right handed beta helix region 308 433 4.0E-14 T 29-03-2018 CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 Pfam PF13229 Right handed beta helix region 65 217 1.3E-10 T 29-03-2018 CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SUPERFAMILY SSF51126 3 293 4.58E-37 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 382 403 200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 173 195 26.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 100 138 1200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 526 551 2200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 424 452 350.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 453 475 3200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 139 161 0.54 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 331 353 530.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 196 225 150.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 354 381 1200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 259 281 1600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS01865 b240c52272631cb698ee2f2abd446cac 581 SMART SM00710 310 330 760.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS11735 83509a1674cfeb646be34314e783b55b 307 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 140 233 1.2E-4 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CXR48_RS11735 83509a1674cfeb646be34314e783b55b 307 SUPERFAMILY SSF52540 25 260 2.52E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11735 83509a1674cfeb646be34314e783b55b 307 Gene3D G3DSA:3.40.50.300 71 279 1.6E-12 T 29-03-2018 CXR48_RS11735 83509a1674cfeb646be34314e783b55b 307 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 28 291 1.0E-123 T 29-03-2018 IPR014217 Sporulation stage III, protein AA CXR48_RS11735 83509a1674cfeb646be34314e783b55b 307 SMART SM00382 135 272 3.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS12330 5a2078b6bb98b2adb9e28339d4dbc55a 96 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 1.7E-23 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CXR48_RS12330 5a2078b6bb98b2adb9e28339d4dbc55a 96 SMART SM01103 2 85 1.3E-44 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CXR48_RS12330 5a2078b6bb98b2adb9e28339d4dbc55a 96 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 1.3E-46 T 29-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CXR48_RS12330 5a2078b6bb98b2adb9e28339d4dbc55a 96 SUPERFAMILY SSF75471 1 94 4.71E-32 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CXR48_RS12330 5a2078b6bb98b2adb9e28339d4dbc55a 96 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 4.0E-45 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CXR48_RS12330 5a2078b6bb98b2adb9e28339d4dbc55a 96 Gene3D G3DSA:3.30.110.60 1 96 2.3E-30 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CXR48_RS14605 cc28292f6b8db9742afaeda9f3e186e9 78 Pfam PF04070 Domain of unknown function (DUF378) 3 61 5.0E-27 T 29-03-2018 IPR007211 Protein of unknown function DUF378 CXR48_RS13495 61e768668d9fe46f3c984bc6060bd855 127 Pfam PF04186 FxsA cytoplasmic membrane protein 6 113 3.1E-34 T 29-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CXR48_RS17455 54790b872cb989761f9ca6d9adfc7cb5 149 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 2.7E-63 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CXR48_RS17455 54790b872cb989761f9ca6d9adfc7cb5 149 Pfam PF02502 Ribose/Galactose Isomerase 3 141 9.0E-56 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CXR48_RS17455 54790b872cb989761f9ca6d9adfc7cb5 149 PIRSF PIRSF005384 1 148 2.6E-58 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CXR48_RS17455 54790b872cb989761f9ca6d9adfc7cb5 149 SUPERFAMILY SSF89623 1 145 1.96E-57 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CXR48_RS17455 54790b872cb989761f9ca6d9adfc7cb5 149 Gene3D G3DSA:3.40.1400.10 1 149 9.8E-66 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CXR48_RS17455 54790b872cb989761f9ca6d9adfc7cb5 149 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 2.8E-51 T 29-03-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 SUPERFAMILY SSF53748 1 393 4.48E-165 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PIRSF PIRSF000724 1 394 1.4E-160 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 Gene3D G3DSA:3.40.50.1260 179 381 7.0E-87 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 3.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 3.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 3.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 3.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 3.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 3.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 3.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 3.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 3.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 43.317 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 Gene3D G3DSA:3.40.50.1260 3 178 2.9E-77 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS16025 8552977d872ea7ca4a63c7a675a355dc 394 Pfam PF00162 Phosphoglycerate kinase 6 383 4.9E-165 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 SUPERFAMILY SSF46785 11 71 2.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 Gene3D G3DSA:3.30.70.920 64 158 1.1E-17 T 29-03-2018 CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 Pfam PF01037 Lrp/AsnC ligand binding domain 79 148 8.7E-11 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 SMART SM00344 12 118 5.7E-42 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 Gene3D G3DSA:1.10.10.10 12 63 3.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 SUPERFAMILY SSF54909 74 156 3.35E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 4.7E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 4.7E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 4.7E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 Pfam PF13404 AsnC-type helix-turn-helix domain 12 52 2.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CXR48_RS17035 78b7c9c7b52e27569dfd8da1acc1646a 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CXR48_RS08645 efff1f256a7dd67747b6bf60e94b541f 314 Pfam PF01715 IPP transferase 41 284 9.7E-87 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CXR48_RS08645 efff1f256a7dd67747b6bf60e94b541f 314 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 8 293 2.1E-117 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CXR48_RS08645 efff1f256a7dd67747b6bf60e94b541f 314 Gene3D G3DSA:3.40.50.300 4 201 2.1E-70 T 29-03-2018 CXR48_RS08645 efff1f256a7dd67747b6bf60e94b541f 314 SUPERFAMILY SSF52540 9 155 2.66E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08645 efff1f256a7dd67747b6bf60e94b541f 314 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 306 30.974 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CXR48_RS08645 efff1f256a7dd67747b6bf60e94b541f 314 SUPERFAMILY SSF52540 127 276 2.62E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08645 efff1f256a7dd67747b6bf60e94b541f 314 SUPERFAMILY SSF52540 7 49 2.62E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08645 efff1f256a7dd67747b6bf60e94b541f 314 Gene3D G3DSA:1.10.287.890 202 282 2.8E-30 T 29-03-2018 CXR48_RS15405 cc9ed7d840cfa391cb8ef66cfaa83c0d 81 Pfam PF10835 Protein of unknown function (DUF2573) 3 79 3.5E-41 T 29-03-2018 IPR020393 Uncharacterised protein family YusU CXR48_RS15405 cc9ed7d840cfa391cb8ef66cfaa83c0d 81 ProDom PD065427 YUSU IG COIL COILED BH3491 1 80 2.0E-33 T 29-03-2018 IPR020393 Uncharacterised protein family YusU CXR48_RS06750 6fb9bdc0dff3d447b5dc73608a1dc497 178 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 176 30.408 T 29-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 CXR48_RS06750 6fb9bdc0dff3d447b5dc73608a1dc497 178 Gene3D G3DSA:2.60.120.10 2 161 1.1E-40 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS06750 6fb9bdc0dff3d447b5dc73608a1dc497 178 SUPERFAMILY SSF51182 8 174 3.96E-36 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS06750 6fb9bdc0dff3d447b5dc73608a1dc497 178 Pfam PF03079 ARD/ARD' family 3 169 2.8E-50 T 29-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 CXR48_RS09910 2df17e9ed5e11c603072162902b0a15e 378 SMART SM00028 220 253 0.018 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS09910 2df17e9ed5e11c603072162902b0a15e 378 SMART SM00028 180 213 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS09910 2df17e9ed5e11c603072162902b0a15e 378 SMART SM00028 139 172 30.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS09910 2df17e9ed5e11c603072162902b0a15e 378 SMART SM00028 262 295 500.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS09910 2df17e9ed5e11c603072162902b0a15e 378 Pfam PF13424 Tetratricopeptide repeat 191 252 3.4E-7 T 29-03-2018 CXR48_RS09910 2df17e9ed5e11c603072162902b0a15e 378 Gene3D G3DSA:1.25.40.10 1 151 1.0E-32 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS09910 2df17e9ed5e11c603072162902b0a15e 378 SUPERFAMILY SSF48452 104 317 1.09E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS09910 2df17e9ed5e11c603072162902b0a15e 378 Gene3D G3DSA:1.25.40.10 152 375 2.1E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS00785 b6e6a668c0d8c2ec78da6a05a59e2aea 122 Gene3D G3DSA:2.40.150.20 1 122 8.5E-52 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CXR48_RS00785 b6e6a668c0d8c2ec78da6a05a59e2aea 122 SMART SM01374 1 122 2.2E-84 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CXR48_RS00785 b6e6a668c0d8c2ec78da6a05a59e2aea 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.5E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CXR48_RS00785 b6e6a668c0d8c2ec78da6a05a59e2aea 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00785 b6e6a668c0d8c2ec78da6a05a59e2aea 122 SUPERFAMILY SSF50193 1 122 5.76E-50 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CXR48_RS00785 b6e6a668c0d8c2ec78da6a05a59e2aea 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.473 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CXR48_RS00785 b6e6a668c0d8c2ec78da6a05a59e2aea 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 9.0E-58 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CXR48_RS15755 73f24fe2e1eb753739e90146acff807e 211 Gene3D G3DSA:3.40.50.360 2 211 4.5E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS15755 73f24fe2e1eb753739e90146acff807e 211 SUPERFAMILY SSF52218 1 209 8.06E-52 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS15755 73f24fe2e1eb753739e90146acff807e 211 Pfam PF02525 Flavodoxin-like fold 3 206 8.8E-45 T 29-03-2018 IPR003680 Flavodoxin-like fold CXR48_RS15755 73f24fe2e1eb753739e90146acff807e 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 27.839 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CXR48_RS03035 716753b66bf7376be0367a24a9c20a38 151 Gene3D G3DSA:3.40.630.30 2 149 1.6E-37 T 29-03-2018 CXR48_RS03035 716753b66bf7376be0367a24a9c20a38 151 SUPERFAMILY SSF55729 7 149 4.32E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS03035 716753b66bf7376be0367a24a9c20a38 151 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 145 9.2E-44 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CXR48_RS03035 716753b66bf7376be0367a24a9c20a38 151 Pfam PF00583 Acetyltransferase (GNAT) family 15 124 7.5E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS11610 1dbe85a156dafa7301adde29e116c421 372 SUPERFAMILY SSF51395 5 340 1.58E-97 T 29-03-2018 CXR48_RS11610 1dbe85a156dafa7301adde29e116c421 372 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 337 6.6E-106 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CXR48_RS11610 1dbe85a156dafa7301adde29e116c421 372 Gene3D G3DSA:3.20.20.70 1 351 3.4E-101 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS14855 5c0bad7ed58f4834e69545b000207f40 97 Gene3D G3DSA:1.10.287.1060 1 97 4.2E-22 T 29-03-2018 CXR48_RS14855 5c0bad7ed58f4834e69545b000207f40 97 SUPERFAMILY SSF140453 4 97 6.41E-24 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CXR48_RS14855 5c0bad7ed58f4834e69545b000207f40 97 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 5.5E-27 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CXR48_RS14855 5c0bad7ed58f4834e69545b000207f40 97 Pfam PF06013 Proteins of 100 residues with WXG 5 89 1.1E-25 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 SUPERFAMILY SSF52540 860 888 4.08E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 SUPERFAMILY SSF52540 342 828 4.08E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 SUPERFAMILY SSF52540 10 180 4.08E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 461 2.1E-97 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 Gene3D G3DSA:3.40.50.300 1 474 3.9E-54 T 29-03-2018 CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1054 1226 9.9E-9 T 29-03-2018 CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 Gene3D G3DSA:3.90.320.10 1003 1234 2.2E-45 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 SUPERFAMILY SSF52980 1014 1232 7.51E-40 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 8 1234 19.982 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 Gene3D G3DSA:3.40.50.300 475 618 3.5E-23 T 29-03-2018 CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 Gene3D G3DSA:1.10.486.10 619 772 4.5E-40 T 29-03-2018 CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 Pfam PF13361 UvrD-like helicase C-terminal domain 472 881 5.9E-33 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CXR48_RS05280 40ad6b4b29fd01567d5f2cf736f3cdff 1234 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 11 1233 0.0 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CXR48_RS05000 f14891e6e326079cdb7477e1fb9af88f 172 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 165 3.0E-38 T 29-03-2018 CXR48_RS05000 f14891e6e326079cdb7477e1fb9af88f 172 Pfam PF17099 Tryptophan transporter TrpP 2 163 8.9E-62 T 29-03-2018 IPR031360 Tryptophan transporter TrpP CXR48_RS15775 3111dc0b7054ed2aed2fefc551ea5e98 259 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15775 3111dc0b7054ed2aed2fefc551ea5e98 259 Pfam PF00005 ABC transporter 17 168 4.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15775 3111dc0b7054ed2aed2fefc551ea5e98 259 Gene3D G3DSA:3.40.50.300 1 244 8.9E-75 T 29-03-2018 CXR48_RS15775 3111dc0b7054ed2aed2fefc551ea5e98 259 SUPERFAMILY SSF52540 1 238 1.39E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS15775 3111dc0b7054ed2aed2fefc551ea5e98 259 SMART SM00382 26 216 7.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15775 3111dc0b7054ed2aed2fefc551ea5e98 259 PIRSF PIRSF039085 1 244 5.4E-107 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CXR48_RS10335 04edcd389b6b336d48b85021c8759f7d 349 Pfam PF16162 Domain of unknown function (DUF4868) 140 278 3.7E-12 T 29-03-2018 IPR032359 Protein of unknown function DUF4868 CXR48_RS17675 1c9a427b0d0fa332ef92b61b1ff8336b 67 SUPERFAMILY SSF47413 2 62 6.48E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS17675 1c9a427b0d0fa332ef92b61b1ff8336b 67 SMART SM00530 4 59 1.8E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS17675 1c9a427b0d0fa332ef92b61b1ff8336b 67 Pfam PF01381 Helix-turn-helix 5 58 2.3E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS17675 1c9a427b0d0fa332ef92b61b1ff8336b 67 Gene3D G3DSA:1.10.260.40 1 67 3.7E-17 T 29-03-2018 CXR48_RS12510 7bff4203ae67e2b9eed15c589a794f9e 266 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 162 172 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site CXR48_RS12510 7bff4203ae67e2b9eed15c589a794f9e 266 Gene3D G3DSA:1.20.1080.10 1 264 1.9E-88 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CXR48_RS12510 7bff4203ae67e2b9eed15c589a794f9e 266 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 77 86 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site CXR48_RS12510 7bff4203ae67e2b9eed15c589a794f9e 266 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 21 253 1.5E-78 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CXR48_RS12510 7bff4203ae67e2b9eed15c589a794f9e 266 Pfam PF01226 Formate/nitrite transporter 8 249 3.7E-78 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 1.9E-35 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 Gene3D G3DSA:3.30.230.10 213 325 4.4E-28 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 Gene3D G3DSA:3.30.565.10 2 204 6.6E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 Pfam PF08676 MutL C terminal dimerisation domain 440 581 3.0E-46 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 1.5E-100 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 SUPERFAMILY SSF54211 190 326 1.02E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 113 3.5E-11 T 29-03-2018 CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 SMART SM00853 439 581 3.3E-52 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 SUPERFAMILY SSF55874 4 213 7.99E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 SMART SM01340 208 326 3.5E-51 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 621 27.588 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CXR48_RS08505 a82b28165209b77b6337ef71ee2943ee 625 SUPERFAMILY SSF118116 435 623 1.83E-53 T 29-03-2018 CXR48_RS12310 caa82b5318b91468d6b64175e15016ba 245 Gene3D G3DSA:3.40.50.150 4 134 1.9E-25 T 29-03-2018 CXR48_RS12310 caa82b5318b91468d6b64175e15016ba 245 Pfam PF13649 Methyltransferase domain 36 130 3.9E-21 T 29-03-2018 CXR48_RS12310 caa82b5318b91468d6b64175e15016ba 245 Gene3D G3DSA:2.20.25.110 138 199 8.5E-20 T 29-03-2018 CXR48_RS12310 caa82b5318b91468d6b64175e15016ba 245 SUPERFAMILY SSF53335 3 241 2.71E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS10205 9b4a68039bc71d5bfa5fb085b32636f3 496 Pfam PF09318 Glycosyl transferase 1 domain A 11 188 2.8E-17 T 29-03-2018 IPR015397 Glycosyl transferase 1, domain A CXR48_RS10205 9b4a68039bc71d5bfa5fb085b32636f3 496 SUPERFAMILY SSF53756 224 495 1.57E-47 T 29-03-2018 CXR48_RS10205 9b4a68039bc71d5bfa5fb085b32636f3 496 Gene3D G3DSA:3.40.50.2000 312 483 1.7E-30 T 29-03-2018 CXR48_RS10205 9b4a68039bc71d5bfa5fb085b32636f3 496 Gene3D G3DSA:2.10.270.10 34 271 5.3E-4 T 29-03-2018 CXR48_RS10205 9b4a68039bc71d5bfa5fb085b32636f3 496 Pfam PF00534 Glycosyl transferases group 1 317 475 7.7E-36 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 112.162 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 5.1E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:3.40.50.300 1 285 6.7E-66 T 29-03-2018 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 SMART SM00838 598 685 8.2E-59 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF54211 477 597 3.03E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF52540 6 279 2.14E-110 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF00679 Elongation factor G C-terminus 598 684 1.9E-31 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF50447 263 402 3.03E-36 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:3.30.70.240 612 689 4.1E-33 T 29-03-2018 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 SMART SM00889 478 596 7.6E-73 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF54980 598 688 2.93E-31 T 29-03-2018 IPR035647 EF-G domain III/V-like CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 5.4E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 5.4E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 5.4E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 5.4E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 5.4E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 181 2.0E-48 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:3.30.230.10 490 611 1.2E-42 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF54980 400 478 2.95E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF03764 Elongation factor G, domain IV 477 595 4.0E-46 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 279 3.0E-69 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:2.40.30.10 286 399 1.2E-31 T 29-03-2018 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF14492 Elongation Factor G, domain II 402 475 9.7E-36 T 29-03-2018 CXR48_RS00715 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:3.30.70.870 400 489 2.7E-35 T 29-03-2018 CXR48_RS12925 ed1b0ad588cede3f80545a139a59ba86 333 Pfam PF05036 Sporulation related domain 180 237 7.2E-9 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CXR48_RS12925 ed1b0ad588cede3f80545a139a59ba86 333 SUPERFAMILY SSF110997 180 245 9.55E-9 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CXR48_RS12925 ed1b0ad588cede3f80545a139a59ba86 333 Gene3D G3DSA:3.30.70.1070 181 251 7.4E-8 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CXR48_RS16105 b1c0e85695b70cfd95bfe8917eebe347 238 Pfam PF02754 Cysteine-rich domain 132 215 1.6E-15 T 29-03-2018 IPR004017 Cysteine-rich domain CXR48_RS16105 b1c0e85695b70cfd95bfe8917eebe347 238 Pfam PF02754 Cysteine-rich domain 3 84 8.3E-18 T 29-03-2018 IPR004017 Cysteine-rich domain CXR48_RS16105 b1c0e85695b70cfd95bfe8917eebe347 238 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 63.666 T 29-03-2018 IPR022822 Lactate utilization protein A GO:0006089 CXR48_RS12435 32e2b69c039c5c86c7487c5236dcc29c 267 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 258 1.8E-43 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12435 32e2b69c039c5c86c7487c5236dcc29c 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 231 1.6E-19 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CXR48_RS12435 32e2b69c039c5c86c7487c5236dcc29c 267 Gene3D G3DSA:3.40.50.1000 1 267 1.3E-30 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12435 32e2b69c039c5c86c7487c5236dcc29c 267 SUPERFAMILY SSF56784 1 262 2.07E-55 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS03575 ff2bee07a177d933ad55c244f092cd13 254 Pfam PF00483 Nucleotidyl transferase 2 242 1.3E-19 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CXR48_RS03575 ff2bee07a177d933ad55c244f092cd13 254 SUPERFAMILY SSF53448 1 254 1.15E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS03575 ff2bee07a177d933ad55c244f092cd13 254 Gene3D G3DSA:3.90.550.10 1 254 4.8E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16490 34ed32c285b32903a3e23aa677e90d1c 396 SUPERFAMILY SSF51338 358 391 2.24E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS16490 34ed32c285b32903a3e23aa677e90d1c 396 SUPERFAMILY SSF51338 4 57 2.24E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS16490 34ed32c285b32903a3e23aa677e90d1c 396 Gene3D G3DSA:3.20.20.140 73 358 7.3E-106 T 29-03-2018 CXR48_RS16490 34ed32c285b32903a3e23aa677e90d1c 396 SUPERFAMILY SSF51556 58 358 2.57E-95 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS16490 34ed32c285b32903a3e23aa677e90d1c 396 Pfam PF01979 Amidohydrolase family 55 384 7.1E-31 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CXR48_RS16490 34ed32c285b32903a3e23aa677e90d1c 396 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 2 385 2.6E-136 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CXR48_RS16490 34ed32c285b32903a3e23aa677e90d1c 396 PIRSF PIRSF038994 3 391 2.2E-135 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CXR48_RS16490 34ed32c285b32903a3e23aa677e90d1c 396 Gene3D G3DSA:2.30.40.10 4 72 2.3E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS03745 1f40de379eda53f6fa3ecb325364ada8 90 SUPERFAMILY SSF54975 1 89 1.11E-27 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CXR48_RS03745 1f40de379eda53f6fa3ecb325364ada8 90 ProSitePatterns PS00151 Acylphosphatase signature 2. 32 48 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CXR48_RS03745 1f40de379eda53f6fa3ecb325364ada8 90 Pfam PF00708 Acylphosphatase 5 88 5.3E-27 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CXR48_RS03745 1f40de379eda53f6fa3ecb325364ada8 90 Gene3D G3DSA:3.30.70.100 1 90 2.8E-29 T 29-03-2018 CXR48_RS03745 1f40de379eda53f6fa3ecb325364ada8 90 PRINTS PR00112 Acylphosphatase signature 3 18 8.0E-5 T 29-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CXR48_RS03745 1f40de379eda53f6fa3ecb325364ada8 90 PRINTS PR00112 Acylphosphatase signature 24 49 8.0E-5 T 29-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CXR48_RS09380 1c97c46a0765666f0c5df17ecd41745a 338 SUPERFAMILY SSF52283 1 138 8.72E-20 T 29-03-2018 CXR48_RS09380 1c97c46a0765666f0c5df17ecd41745a 338 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CXR48_RS09380 1c97c46a0765666f0c5df17ecd41745a 338 Gene3D G3DSA:3.40.50.720 1 117 4.1E-18 T 29-03-2018 CXR48_RS09380 1c97c46a0765666f0c5df17ecd41745a 338 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 236 8.5E-10 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CXR48_RS09380 1c97c46a0765666f0c5df17ecd41745a 338 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 291 5.9E-57 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CXR48_RS09380 1c97c46a0765666f0c5df17ecd41745a 338 Gene3D G3DSA:3.40.50.720 118 294 1.2E-50 T 29-03-2018 CXR48_RS09380 1c97c46a0765666f0c5df17ecd41745a 338 SUPERFAMILY SSF51735 106 291 1.29E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS05105 84db633b540552b55a76b5facab5c9ba 331 Gene3D G3DSA:3.30.930.10 2 246 3.5E-71 T 29-03-2018 CXR48_RS05105 84db633b540552b55a76b5facab5c9ba 331 SUPERFAMILY SSF82649 245 331 8.89E-28 T 29-03-2018 CXR48_RS05105 84db633b540552b55a76b5facab5c9ba 331 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 153 7.8E-12 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CXR48_RS05105 84db633b540552b55a76b5facab5c9ba 331 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 323 2.1E-139 T 29-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CXR48_RS05105 84db633b540552b55a76b5facab5c9ba 331 Gene3D G3DSA:3.30.390.50 247 331 2.0E-28 T 29-03-2018 CXR48_RS05105 84db633b540552b55a76b5facab5c9ba 331 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 246 330 3.7E-32 T 29-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CXR48_RS05105 84db633b540552b55a76b5facab5c9ba 331 SUPERFAMILY SSF55681 2 244 1.42E-81 T 29-03-2018 CXR48_RS07185 30ac6750aee47a92675db63517b341ed 69 Hamap MF_01553 UPF0356 protein . 1 69 22.85 T 29-03-2018 IPR009907 Protein of unknown function DUF1447 CXR48_RS07185 30ac6750aee47a92675db63517b341ed 69 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 2.5E-30 T 29-03-2018 IPR009907 Protein of unknown function DUF1447 CXR48_RS07185 30ac6750aee47a92675db63517b341ed 69 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 6.0E-30 T 29-03-2018 IPR009907 Protein of unknown function DUF1447 CXR48_RS15490 2428c966681c75edf929367f523cf1c2 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 253 343 2.4E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15490 2428c966681c75edf929367f523cf1c2 360 SUPERFAMILY SSF55874 222 343 2.23E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15490 2428c966681c75edf929367f523cf1c2 360 SMART SM00304 74 126 8.7E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CXR48_RS15490 2428c966681c75edf929367f523cf1c2 360 PIRSF PIRSF037431 7 352 1.4E-127 T 29-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 CXR48_RS15490 2428c966681c75edf929367f523cf1c2 360 Gene3D G3DSA:3.30.565.10 215 352 3.1E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15490 2428c966681c75edf929367f523cf1c2 360 Pfam PF07730 Histidine kinase 150 217 1.4E-18 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CXR48_RS15490 2428c966681c75edf929367f523cf1c2 360 SMART SM00387 253 346 1.1E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS17755 db956ce8a2a89d8a2516c9302dc93ca0 459 PIRSF PIRSF006060 5 459 6.1E-87 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS17755 db956ce8a2a89d8a2516c9302dc93ca0 459 Pfam PF13520 Amino acid permease 29 430 5.5E-62 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS11910 e412468aefec4c7c09d4da546a0a40a3 81 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 79 2.0E-35 T 29-03-2018 IPR020254 Protein of unknown function DUF2626 CXR48_RS11910 e412468aefec4c7c09d4da546a0a40a3 81 Pfam PF11117 Protein of unknown function (DUF2626) 1 74 2.0E-36 T 29-03-2018 IPR020254 Protein of unknown function DUF2626 CXR48_RS08185 989cf397dd308f18f50878037e8904d6 297 SUPERFAMILY SSF52540 27 273 3.29E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08185 989cf397dd308f18f50878037e8904d6 297 PIRSF PIRSF003092 2 295 2.1E-76 T 29-03-2018 IPR025501 ATP binding protein MinD CXR48_RS08185 989cf397dd308f18f50878037e8904d6 297 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 29 264 2.3E-18 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CXR48_RS08185 989cf397dd308f18f50878037e8904d6 297 Gene3D G3DSA:3.40.50.300 27 272 6.4E-45 T 29-03-2018 CXR48_RS15965 d0d6a24d96d2903905f5438d7f28b5d4 306 Pfam PF01261 Xylose isomerase-like TIM barrel 50 228 1.7E-6 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS15965 d0d6a24d96d2903905f5438d7f28b5d4 306 Gene3D G3DSA:3.20.20.150 19 79 0.13 T 29-03-2018 CXR48_RS15965 d0d6a24d96d2903905f5438d7f28b5d4 306 Gene3D G3DSA:3.20.20.150 80 305 3.7E-13 T 29-03-2018 CXR48_RS15965 d0d6a24d96d2903905f5438d7f28b5d4 306 SUPERFAMILY SSF51658 31 259 1.66E-14 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS08875 2e488a3b88bf7a94214e32cd12946e75 216 SUPERFAMILY SSF53041 1 149 3.92E-27 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CXR48_RS08875 2e488a3b88bf7a94214e32cd12946e75 216 Gene3D G3DSA:1.10.10.60 156 212 3.2E-4 T 29-03-2018 CXR48_RS08875 2e488a3b88bf7a94214e32cd12946e75 216 Pfam PF00239 Resolvase, N terminal domain 3 147 5.0E-27 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CXR48_RS08875 2e488a3b88bf7a94214e32cd12946e75 216 SMART SM00857 3 149 1.8E-35 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CXR48_RS08875 2e488a3b88bf7a94214e32cd12946e75 216 Gene3D G3DSA:3.40.50.1390 1 155 7.6E-33 T 29-03-2018 CXR48_RS06080 37e59c7b2d00f533b60e284b4e9a9230 463 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 24 458 2.4E-148 T 29-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CXR48_RS06080 37e59c7b2d00f533b60e284b4e9a9230 463 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 75 102 - T 29-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 CXR48_RS06080 37e59c7b2d00f533b60e284b4e9a9230 463 SUPERFAMILY SSF103473 25 448 6.02E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS06080 37e59c7b2d00f533b60e284b4e9a9230 463 Gene3D G3DSA:1.20.1250.20 25 227 1.2E-15 T 29-03-2018 CXR48_RS06080 37e59c7b2d00f533b60e284b4e9a9230 463 Gene3D G3DSA:1.20.1250.20 228 458 2.8E-17 T 29-03-2018 CXR48_RS06080 37e59c7b2d00f533b60e284b4e9a9230 463 Pfam PF13347 MFS/sugar transport protein 26 446 1.9E-95 T 29-03-2018 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 SUPERFAMILY SSF53822 61 324 4.91E-63 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 SMART SM00354 1 71 9.1E-37 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 Pfam PF13377 Periplasmic binding protein-like domain 169 322 1.1E-28 T 29-03-2018 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.4E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.4E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 SUPERFAMILY SSF47413 2 59 3.0E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.3E-22 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 Gene3D G3DSA:3.40.50.2300 158 325 8.5E-45 T 29-03-2018 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 Gene3D G3DSA:1.10.260.40 2 57 7.9E-22 T 29-03-2018 CXR48_RS16940 61b250fe9ba0c797874acd926605d409 329 Gene3D G3DSA:3.40.50.2300 58 157 8.9E-23 T 29-03-2018 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 SUPERFAMILY SSF68912 5 49 2.59E-10 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 SMART SM00959 8 50 2.7E-14 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 SUPERFAMILY SSF52540 92 370 1.33E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 Gene3D G3DSA:3.40.50.300 117 366 3.9E-50 T 29-03-2018 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 Pfam PF07497 Rho termination factor, RNA-binding domain 54 127 3.3E-31 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 SUPERFAMILY SSF50249 52 127 4.57E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 SMART SM00357 55 120 7.8E-20 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 416 221.833 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 Gene3D G3DSA:2.40.50.140 52 116 9.2E-28 T 29-03-2018 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 SMART SM00382 169 354 4.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 Gene3D G3DSA:1.10.720.10 2 46 1.5E-15 T 29-03-2018 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 Pfam PF07498 Rho termination factor, N-terminal domain 9 49 8.4E-15 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 414 1.4E-206 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CXR48_RS17535 4e88df62c43ceb1ea55d8e240742588f 428 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 158 362 1.6E-19 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS19125 27cfca5edc5000323b2cce3063ba67da 187 Gene3D G3DSA:3.30.200.20 8 85 1.0E-6 T 29-03-2018 CXR48_RS19125 27cfca5edc5000323b2cce3063ba67da 187 Gene3D G3DSA:1.10.510.10 86 173 1.4E-7 T 29-03-2018 CXR48_RS19125 27cfca5edc5000323b2cce3063ba67da 187 SUPERFAMILY SSF56112 22 147 3.1E-17 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS10015 679a5afd742bc87d9d8209922b64193c 422 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CXR48_RS10015 679a5afd742bc87d9d8209922b64193c 422 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 421 2.2E-28 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CXR48_RS10015 679a5afd742bc87d9d8209922b64193c 422 SUPERFAMILY SSF53686 13 366 5.63E-101 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS10015 679a5afd742bc87d9d8209922b64193c 422 Gene3D G3DSA:3.40.1020.10 233 422 4.9E-36 T 29-03-2018 CXR48_RS10015 679a5afd742bc87d9d8209922b64193c 422 TIGRFAM TIGR02079 THD1: threonine dehydratase 14 422 5.0E-195 T 29-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CXR48_RS10015 679a5afd742bc87d9d8209922b64193c 422 Gene3D G3DSA:3.40.50.1100 20 180 1.7E-41 T 29-03-2018 CXR48_RS10015 679a5afd742bc87d9d8209922b64193c 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 316 8.3E-76 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS15585 ef393d0a56531833a6d394d1867f934f 268 Pfam PF00005 ABC transporter 20 167 9.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15585 ef393d0a56531833a6d394d1867f934f 268 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15585 ef393d0a56531833a6d394d1867f934f 268 SMART SM00382 28 217 4.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15585 ef393d0a56531833a6d394d1867f934f 268 Gene3D G3DSA:3.40.50.300 1 248 3.1E-60 T 29-03-2018 CXR48_RS15585 ef393d0a56531833a6d394d1867f934f 268 SUPERFAMILY SSF52540 4 229 5.22E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 Pfam PF00199 Catalase 7 388 1.3E-199 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 104 121 2.8E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 123 141 2.8E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 20 43 2.8E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 288 315 2.8E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 320 346 2.8E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 83 101 2.8E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 Gene3D G3DSA:2.40.180.10 1 357 1.8E-171 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 SUPERFAMILY SSF56634 4 479 1.44E-218 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 SMART SM01060 7 391 3.9E-298 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 PIRSF PIRSF038928 1 479 3.1E-228 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS04385 487a04353c84a510b9d2d0432ee4dd7d 481 Pfam PF06628 Catalase-related immune-responsive 414 475 9.3E-27 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CXR48_RS13295 450841dba10779372ecda0f90a991a05 229 TIGRFAM TIGR00760 araD: L-ribulose-5-phosphate 4-epimerase 1 228 1.6E-126 T 29-03-2018 IPR004661 L-ribulose-5-phosphate 4-epimerase GO:0008270|GO:0008742|GO:0019572 KEGG: 00040+5.1.3.4|KEGG: 00053+5.1.3.4|MetaCyc: PWY-6961 CXR48_RS13295 450841dba10779372ecda0f90a991a05 229 SMART SM01007 7 195 2.3E-62 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CXR48_RS13295 450841dba10779372ecda0f90a991a05 229 Gene3D G3DSA:3.40.225.10 1 228 2.7E-57 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CXR48_RS13295 450841dba10779372ecda0f90a991a05 229 SUPERFAMILY SSF53639 1 220 3.73E-66 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CXR48_RS13295 450841dba10779372ecda0f90a991a05 229 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 194 2.8E-46 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CXR48_RS08725 679ed73f52b40d669c5542e3f8c29c1d 463 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 65 90 - T 29-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 CXR48_RS08725 679ed73f52b40d669c5542e3f8c29c1d 463 Gene3D G3DSA:1.20.1250.20 218 454 1.6E-17 T 29-03-2018 CXR48_RS08725 679ed73f52b40d669c5542e3f8c29c1d 463 SUPERFAMILY SSF103473 17 425 5.1E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS08725 679ed73f52b40d669c5542e3f8c29c1d 463 Gene3D G3DSA:1.20.1250.20 15 217 1.3E-22 T 29-03-2018 CXR48_RS08725 679ed73f52b40d669c5542e3f8c29c1d 463 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 14 450 2.7E-155 T 29-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CXR48_RS08725 679ed73f52b40d669c5542e3f8c29c1d 463 Pfam PF13347 MFS/sugar transport protein 16 437 6.7E-104 T 29-03-2018 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Pfam PF14579 Helix-hairpin-helix motif 1353 1429 2.0E-9 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 SMART SM00481 335 402 2.2E-29 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 413 638 1.2E-78 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Gene3D G3DSA:2.40.50.140 219 320 1.7E-20 T 29-03-2018 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Gene3D G3DSA:1.20.5.140 571 590 4.0E-12 T 29-03-2018 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Pfam PF00929 Exonuclease 422 577 8.5E-43 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Gene3D G3DSA:3.30.420.10 412 570 6.3E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 SMART SM00479 420 587 1.5E-57 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Pfam PF02811 PHP domain 336 695 3.6E-55 T 29-03-2018 IPR004013 PHP domain GO:0003824 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 825 1237 3.2E-98 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 SUPERFAMILY SSF53098 420 876 1.97E-109 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Gene3D G3DSA:3.20.20.140 604 796 2.2E-22 T 29-03-2018 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 230 1437 0.0 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Pfam PF14480 DNA polymerase III polC-type N-terminus I 10 79 5.5E-21 T 29-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 SUPERFAMILY SSF50249 234 321 3.83E-11 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1437 463.639 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Pfam PF11490 DNA polymerase III polC-type N-terminus II 96 207 7.3E-29 T 29-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS08270 418f72f9a38dd50e6128926f158ab427 1437 Gene3D G3DSA:1.10.150.280 1370 1424 7.5E-4 T 29-03-2018 CXR48_RS02615 e0cb0bf0fb833518021150fca2741501 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 29-03-2018 IPR001455 TusA-like domain CXR48_RS02615 e0cb0bf0fb833518021150fca2741501 75 Gene3D G3DSA:3.30.110.40 1 75 8.0E-28 T 29-03-2018 IPR001455 TusA-like domain CXR48_RS02615 e0cb0bf0fb833518021150fca2741501 75 SUPERFAMILY SSF64307 2 75 4.58E-26 T 29-03-2018 IPR001455 TusA-like domain CXR48_RS02615 e0cb0bf0fb833518021150fca2741501 75 Pfam PF01206 Sulfurtransferase TusA 5 74 3.9E-24 T 29-03-2018 IPR001455 TusA-like domain CXR48_RS13335 731c373986627df519121790aed4a2a0 66 SUPERFAMILY SSF143034 2 62 6.15E-22 T 29-03-2018 CXR48_RS13335 731c373986627df519121790aed4a2a0 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.5E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CXR48_RS13335 731c373986627df519121790aed4a2a0 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.5E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CXR48_RS13335 731c373986627df519121790aed4a2a0 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.5E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CXR48_RS13335 731c373986627df519121790aed4a2a0 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS13335 731c373986627df519121790aed4a2a0 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 4.3E-26 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CXR48_RS13335 731c373986627df519121790aed4a2a0 66 Pfam PF01632 Ribosomal protein L35 2 61 6.1E-25 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS13335 731c373986627df519121790aed4a2a0 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.872 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CXR48_RS07435 3495d29387f59660fb941d1af2b98d84 110 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 1 110 4.3E-56 T 29-03-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CXR48_RS07435 3495d29387f59660fb941d1af2b98d84 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 29 101 1.5E-12 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CXR48_RS16855 ea2e34e6b18cd9febf1188986840b7a2 483 PIRSF PIRSF005690 1 483 7.1E-184 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS16855 ea2e34e6b18cd9febf1188986840b7a2 483 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 13 472 6.5E-170 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS02195 a5e08a25020367764a10c62fa75cb256 361 Gene3D G3DSA:1.50.10.10 29 356 5.6E-46 T 29-03-2018 CXR48_RS02195 a5e08a25020367764a10c62fa75cb256 361 SUPERFAMILY SSF48208 5 352 9.9E-48 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 444 7.2E-190 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 Pfam PF11638 DnaA N-terminal domain 7 66 2.0E-18 T 29-03-2018 IPR024633 DnaA N-terminal domain CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 Gene3D G3DSA:1.10.8.60 277 348 2.0E-29 T 29-03-2018 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 SUPERFAMILY SSF52540 111 323 4.07E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 Gene3D G3DSA:1.10.1750.10 349 446 2.1E-35 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 SMART SM00760 355 424 4.7E-42 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 SUPERFAMILY SSF48295 342 446 2.04E-36 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 Pfam PF00308 Bacterial dnaA protein 111 327 1.4E-107 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 Gene3D G3DSA:3.40.50.300 108 275 6.6E-23 T 29-03-2018 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 446 35.249 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 356 424 6.2E-31 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CXR48_RS00005 156060d64019eda3e0271fc22e2d1dc2 446 SMART SM00382 143 271 1.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS09515 83524c0c10ae69ad065a9d6f00a453ca 160 Pfam PF00011 Hsp20/alpha crystallin family 61 152 9.8E-10 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CXR48_RS09515 83524c0c10ae69ad065a9d6f00a453ca 160 SUPERFAMILY SSF49764 55 148 1.4E-15 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS09515 83524c0c10ae69ad065a9d6f00a453ca 160 Gene3D G3DSA:2.60.40.790 1 159 4.1E-16 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS04135 14dddcee545f33fcf1c304dfd72f88d4 50 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 17 48 9.6E-23 T 29-03-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 CXR48_RS04135 14dddcee545f33fcf1c304dfd72f88d4 50 Pfam PF08176 Small acid-soluble spore protein K family 2 48 7.5E-30 T 29-03-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 CXR48_RS04135 14dddcee545f33fcf1c304dfd72f88d4 50 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 2 50 19.037 T 29-03-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 CXR48_RS05640 8f66aac6166e51bf64fb87065af18ad7 192 Pfam PF13508 Acetyltransferase (GNAT) domain 49 110 3.5E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS05640 8f66aac6166e51bf64fb87065af18ad7 192 Gene3D G3DSA:3.40.630.30 24 167 5.7E-9 T 29-03-2018 CXR48_RS05640 8f66aac6166e51bf64fb87065af18ad7 192 SUPERFAMILY SSF55729 47 114 5.05E-7 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS02960 0120e310dc5d08d8ff422a3347fdf8cf 520 Pfam PF13520 Amino acid permease 12 419 6.1E-46 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS02960 0120e310dc5d08d8ff422a3347fdf8cf 520 PIRSF PIRSF006060 1 460 8.4E-86 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS02960 0120e310dc5d08d8ff422a3347fdf8cf 520 PIRSF PIRSF006060 428 516 360.0 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS16495 bfeaa64851025a62887492b1c7a4b3ae 241 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 43.778 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CXR48_RS16495 bfeaa64851025a62887492b1c7a4b3ae 241 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 226 9.6E-18 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CXR48_RS16495 bfeaa64851025a62887492b1c7a4b3ae 241 SUPERFAMILY SSF100950 1 238 3.35E-92 T 29-03-2018 CXR48_RS16495 bfeaa64851025a62887492b1c7a4b3ae 241 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 238 2.1E-102 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CXR48_RS16495 bfeaa64851025a62887492b1c7a4b3ae 241 Gene3D G3DSA:3.40.50.1360 1 240 4.1E-75 T 29-03-2018 CXR48_RS00815 48d499cfa4b1df5f0b745ff3c3d57a8e 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 8.5E-54 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00815 48d499cfa4b1df5f0b745ff3c3d57a8e 120 SUPERFAMILY SSF53137 7 118 7.1E-57 T 29-03-2018 CXR48_RS00815 48d499cfa4b1df5f0b745ff3c3d57a8e 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 1.1E-49 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00815 48d499cfa4b1df5f0b745ff3c3d57a8e 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 30.848 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00815 48d499cfa4b1df5f0b745ff3c3d57a8e 120 Gene3D G3DSA:3.30.420.100 1 120 1.4E-47 T 29-03-2018 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 SUPERFAMILY SSF51735 5 166 1.01E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 Pfam PF02056 Family 4 glycosyl hydrolase 7 186 4.9E-71 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 140 171 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 SUPERFAMILY SSF56327 170 441 1.15E-91 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 2.6E-59 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 76 92 2.6E-59 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 2.6E-59 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 2.6E-59 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 2.6E-59 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 2.6E-59 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 7 22 2.6E-59 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 417 1.7E-49 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 Gene3D G3DSA:3.90.1820.10 276 443 1.9E-41 T 29-03-2018 CXR48_RS03995 dd7be8aa424e2d0b2d1d9f5943c8594e 449 Gene3D G3DSA:3.90.1820.10 4 275 3.6E-61 T 29-03-2018 CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 PRINTS PR00084 Mannitol dehydrogenase signature 205 218 1.4E-5 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 PRINTS PR00084 Mannitol dehydrogenase signature 164 177 1.4E-5 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 PRINTS PR00084 Mannitol dehydrogenase signature 235 250 1.4E-5 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 PRINTS PR00084 Mannitol dehydrogenase signature 19 29 1.4E-5 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 Gene3D G3DSA:1.10.1040.10 272 476 2.8E-46 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 Gene3D G3DSA:3.40.50.720 6 268 6.2E-68 T 29-03-2018 CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 18 172 5.6E-19 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 SUPERFAMILY SSF51735 14 267 1.34E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 SUPERFAMILY SSF48179 273 475 4.76E-38 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS06090 7d2c5388ac1f6a86ff4d610c90286406 481 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 205 398 2.1E-48 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CXR48_RS06305 6eb5c15e617d8ced76e06ba3af4494ce 219 SUPERFAMILY SSF54106 158 218 9.29E-8 T 29-03-2018 IPR018392 LysM domain CXR48_RS06305 6eb5c15e617d8ced76e06ba3af4494ce 219 Gene3D G3DSA:3.10.350.10 157 219 4.3E-15 T 29-03-2018 CXR48_RS06305 6eb5c15e617d8ced76e06ba3af4494ce 219 Pfam PF01476 LysM domain 161 218 1.5E-19 T 29-03-2018 IPR018392 LysM domain CXR48_RS06305 6eb5c15e617d8ced76e06ba3af4494ce 219 SMART SM00257 160 218 1.7E-8 T 29-03-2018 IPR018392 LysM domain CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 Gene3D G3DSA:3.40.50.720 1 255 1.4E-56 T 29-03-2018 CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 SUPERFAMILY SSF51735 2 248 5.41E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13565 463faa34b1b5ebaa23bb0db7d9ff42ea 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 247 2.3E-46 T 29-03-2018 CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 Gene3D G3DSA:3.20.20.80 2 466 5.9E-144 T 29-03-2018 CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 SUPERFAMILY SSF51445 2 463 3.57E-157 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 TIGRFAM TIGR01233 lacG: 6-phospho-beta-galactosidase 3 465 8.3E-216 T 29-03-2018 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85 CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 6.4E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 6.4E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 434 446 6.4E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 6.4E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 6.4E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site CXR48_RS05960 0b431f8f6dcf6b766c682aef6542ba03 466 Pfam PF00232 Glycosyl hydrolase family 1 4 463 8.9E-156 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS11670 02b70afcfc461189c516aefa7ddd6e62 448 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 357 3.1E-140 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CXR48_RS11670 02b70afcfc461189c516aefa7ddd6e62 448 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 441 30.729 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CXR48_RS11670 02b70afcfc461189c516aefa7ddd6e62 448 Pfam PF13742 OB-fold nucleic acid binding domain 8 102 2.3E-31 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CXR48_RS11670 02b70afcfc461189c516aefa7ddd6e62 448 Pfam PF02601 Exonuclease VII, large subunit 125 438 2.2E-102 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CXR48_RS11670 02b70afcfc461189c516aefa7ddd6e62 448 Gene3D G3DSA:2.40.50.140 7 103 2.2E-9 T 29-03-2018 CXR48_RS10730 6663cefddd2afb622d3a4664d109bea6 265 Pfam PF00290 Tryptophan synthase alpha chain 6 238 4.2E-91 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CXR48_RS10730 6663cefddd2afb622d3a4664d109bea6 265 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 40 53 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CXR48_RS10730 6663cefddd2afb622d3a4664d109bea6 265 SUPERFAMILY SSF51366 6 233 5.09E-77 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CXR48_RS10730 6663cefddd2afb622d3a4664d109bea6 265 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 5 261 34.147 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CXR48_RS10730 6663cefddd2afb622d3a4664d109bea6 265 Gene3D G3DSA:3.20.20.70 3 261 6.9E-64 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS10730 6663cefddd2afb622d3a4664d109bea6 265 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 5 258 2.7E-94 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CXR48_RS15050 56980fb85f95afa885496fee56849f65 78 Pfam PF01106 NifU-like domain 10 75 3.8E-28 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CXR48_RS15050 56980fb85f95afa885496fee56849f65 78 Gene3D G3DSA:3.30.300.130 2 78 2.6E-29 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CXR48_RS15050 56980fb85f95afa885496fee56849f65 78 SUPERFAMILY SSF117916 2 77 1.14E-26 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CXR48_RS15050 56980fb85f95afa885496fee56849f65 78 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 65 9.0E-23 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CXR48_RS07450 a38f4e84280a5998f534c1210207810a 147 Gene3D G3DSA:3.10.580.10 1 132 2.2E-27 T 29-03-2018 CXR48_RS07450 a38f4e84280a5998f534c1210207810a 147 Pfam PF00571 CBS domain 71 119 4.0E-13 T 29-03-2018 IPR000644 CBS domain CXR48_RS07450 a38f4e84280a5998f534c1210207810a 147 Pfam PF00571 CBS domain 6 56 5.1E-11 T 29-03-2018 IPR000644 CBS domain CXR48_RS07450 a38f4e84280a5998f534c1210207810a 147 SMART SM00116 77 124 1.6E-8 T 29-03-2018 IPR000644 CBS domain CXR48_RS07450 a38f4e84280a5998f534c1210207810a 147 SMART SM00116 11 60 6.4E-5 T 29-03-2018 IPR000644 CBS domain CXR48_RS07450 a38f4e84280a5998f534c1210207810a 147 SUPERFAMILY SSF54631 2 119 6.57E-31 T 29-03-2018 CXR48_RS12175 b87ccc47496cf451656c225754a76da8 394 Pfam PF06898 Putative stage IV sporulation protein YqfD 8 384 1.7E-115 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CXR48_RS12175 b87ccc47496cf451656c225754a76da8 394 PIRSF PIRSF029895 1 394 7.3E-165 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CXR48_RS12175 b87ccc47496cf451656c225754a76da8 394 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 386 3.2E-111 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CXR48_RS17470 8c508a5db9cef4862bb662a9f41e1ae1 346 Pfam PF01300 Telomere recombination 26 203 2.3E-58 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CXR48_RS17470 8c508a5db9cef4862bb662a9f41e1ae1 346 PIRSF PIRSF004930 1 346 6.3E-132 T 29-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CXR48_RS17470 8c508a5db9cef4862bb662a9f41e1ae1 346 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 17 212 1.3E-69 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CXR48_RS17470 8c508a5db9cef4862bb662a9f41e1ae1 346 SUPERFAMILY SSF55821 19 215 9.77E-68 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CXR48_RS17470 8c508a5db9cef4862bb662a9f41e1ae1 346 Gene3D G3DSA:3.90.870.10 7 219 6.7E-80 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CXR48_RS17470 8c508a5db9cef4862bb662a9f41e1ae1 346 Pfam PF03481 Putative GTP-binding controlling metal-binding 205 341 3.4E-26 T 29-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 Pfam PF00154 recA bacterial DNA recombination protein 7 267 3.1E-147 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 SUPERFAMILY SSF54752 267 326 1.1E-21 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 Hamap MF_00268 Protein RecA [recA]. 4 328 53.152 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 PRINTS PR00142 RecA protein signature 296 313 3.8E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 PRINTS PR00142 RecA protein signature 92 121 3.8E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 PRINTS PR00142 RecA protein signature 209 237 3.8E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 PRINTS PR00142 RecA protein signature 242 271 3.8E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 PRINTS PR00142 RecA protein signature 126 155 3.8E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 PRINTS PR00142 RecA protein signature 164 193 3.8E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 Gene3D G3DSA:3.30.250.10 268 324 1.9E-25 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 ProSitePatterns PS00321 recA signature. 212 220 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 Gene3D G3DSA:3.40.50.300 25 267 8.6E-47 T 29-03-2018 CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 SUPERFAMILY SSF52540 3 266 1.77E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 SMART SM00382 56 227 7.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS08450 6b6bb5f2ef8d4d854521d7e70b3afd15 347 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 323 3.9E-177 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CXR48_RS06030 057505ccfc2ef712a45cba09d380a85c 394 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 216 358 4.2E-13 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CXR48_RS06030 057505ccfc2ef712a45cba09d380a85c 394 Gene3D G3DSA:3.40.50.2000 211 372 8.1E-37 T 29-03-2018 CXR48_RS06030 057505ccfc2ef712a45cba09d380a85c 394 SUPERFAMILY SSF53756 5 387 9.11E-77 T 29-03-2018 CXR48_RS06030 057505ccfc2ef712a45cba09d380a85c 394 Gene3D G3DSA:3.40.50.2000 3 210 2.5E-25 T 29-03-2018 CXR48_RS06030 057505ccfc2ef712a45cba09d380a85c 394 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 9 388 2.3E-132 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CXR48_RS03445 98e74fb43dc96220bee6dbf57c887865 157 Gene3D G3DSA:3.30.500.20 3 117 3.9E-35 T 29-03-2018 CXR48_RS03445 98e74fb43dc96220bee6dbf57c887865 157 Pfam PF04634 Protein of unknown function, DUF600 6 151 4.5E-53 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03445 98e74fb43dc96220bee6dbf57c887865 157 SUPERFAMILY SSF160424 4 154 1.29E-50 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03445 98e74fb43dc96220bee6dbf57c887865 157 TIGRFAM TIGR01741 staph_tand_hypo: conserved hypothetical protein 2 156 8.5E-57 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS01695 a01bfa3aaeeab59d2f928b98fb2b749e 303 Gene3D G3DSA:3.20.20.220 8 303 4.1E-72 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CXR48_RS01695 a01bfa3aaeeab59d2f928b98fb2b749e 303 SUPERFAMILY SSF51730 36 298 1.96E-73 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CXR48_RS01695 a01bfa3aaeeab59d2f928b98fb2b749e 303 Pfam PF01619 Proline dehydrogenase 43 292 5.5E-37 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CXR48_RS01695 a01bfa3aaeeab59d2f928b98fb2b749e 303 PIRSF PIRSF000196 1 303 6.1E-125 T 29-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 SUPERFAMILY SSF53633 1 289 2.49E-65 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 Gene3D G3DSA:3.30.70.260 370 450 7.0E-23 T 29-03-2018 CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 Pfam PF13840 ACT domain 381 444 3.7E-8 T 29-03-2018 IPR027795 GATS-like ACT domain CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 PIRSF PIRSF000726 1 451 4.2E-74 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 SUPERFAMILY SSF55021 372 449 3.49E-22 T 29-03-2018 CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 SUPERFAMILY SSF55021 296 361 2.98E-7 T 29-03-2018 CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 Gene3D G3DSA:3.30.70.260 284 369 2.8E-15 T 29-03-2018 CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 448 1.1E-76 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 Gene3D G3DSA:3.40.1160.10 1 283 1.6E-54 T 29-03-2018 CXR48_RS01960 50cd43096db33173614f82dc59888efd 454 Pfam PF00696 Amino acid kinase family 2 276 1.3E-37 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS14160 63b7c37e9545465314b3675bb84e5a80 260 SMART SM00382 32 212 7.8E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS14160 63b7c37e9545465314b3675bb84e5a80 260 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS14160 63b7c37e9545465314b3675bb84e5a80 260 Pfam PF00005 ABC transporter 24 162 3.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS14160 63b7c37e9545465314b3675bb84e5a80 260 SUPERFAMILY SSF52540 4 227 1.56E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14160 63b7c37e9545465314b3675bb84e5a80 260 Gene3D G3DSA:3.40.50.300 1 241 4.0E-54 T 29-03-2018 CXR48_RS05335 c6185a1cbcb5de8f03e877fc23274393 301 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 93 300 2.9E-72 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CXR48_RS05335 c6185a1cbcb5de8f03e877fc23274393 301 SUPERFAMILY SSF56529 80 300 5.23E-80 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CXR48_RS05335 c6185a1cbcb5de8f03e877fc23274393 301 Gene3D G3DSA:3.90.850.10 43 301 2.2E-84 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CXR48_RS14200 58d0034e78b5d4d7c47d63ded0fec6df 75 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 75 2.2E-40 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CXR48_RS14200 58d0034e78b5d4d7c47d63ded0fec6df 75 SMART SM01234 1 68 6.0E-52 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CXR48_RS14200 58d0034e78b5d4d7c47d63ded0fec6df 75 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 1.0E-24 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CXR48_RS14200 58d0034e78b5d4d7c47d63ded0fec6df 75 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 26.32 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CXR48_RS14200 58d0034e78b5d4d7c47d63ded0fec6df 75 Pfam PF01809 Haemolytic domain 2 68 3.6E-33 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CXR48_RS08275 56231006b81a839b9bbbdab675f602dd 156 Gene3D G3DSA:3.30.300.70 1 81 2.6E-29 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CXR48_RS08275 56231006b81a839b9bbbdab675f602dd 156 SUPERFAMILY SSF74942 85 156 2.88E-21 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CXR48_RS08275 56231006b81a839b9bbbdab675f602dd 156 SUPERFAMILY SSF75420 3 84 8.24E-27 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CXR48_RS08275 56231006b81a839b9bbbdab675f602dd 156 Pfam PF17384 RimP C-terminal SH3 domain 87 156 1.4E-22 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CXR48_RS08275 56231006b81a839b9bbbdab675f602dd 156 Gene3D G3DSA:2.30.30.180 88 154 7.3E-22 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CXR48_RS08275 56231006b81a839b9bbbdab675f602dd 156 Pfam PF02576 RimP N-terminal domain 13 84 2.9E-30 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CXR48_RS08275 56231006b81a839b9bbbdab675f602dd 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 156 24.721 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CXR48_RS02020 47cd5c9aa7d908f959f43d674a98ca4f 435 SUPERFAMILY SSF53383 33 435 1.51E-130 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS02020 47cd5c9aa7d908f959f43d674a98ca4f 435 Gene3D G3DSA:3.40.640.10 199 321 2.7E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS02020 47cd5c9aa7d908f959f43d674a98ca4f 435 Gene3D G3DSA:3.90.1150.10 322 435 2.0E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS02020 47cd5c9aa7d908f959f43d674a98ca4f 435 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 16 435 4.0E-224 T 29-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CXR48_RS02020 47cd5c9aa7d908f959f43d674a98ca4f 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 287 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS02020 47cd5c9aa7d908f959f43d674a98ca4f 435 PIRSF PIRSF000521 130 435 6.3E-36 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS02020 47cd5c9aa7d908f959f43d674a98ca4f 435 PIRSF PIRSF000521 29 137 1.2E-7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS02020 47cd5c9aa7d908f959f43d674a98ca4f 435 Pfam PF00202 Aminotransferase class-III 33 435 8.7E-124 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS02020 47cd5c9aa7d908f959f43d674a98ca4f 435 Gene3D G3DSA:3.90.1150.10 2 198 2.2E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS00265 ff0df107b0a2afcbddb1074576a970a2 441 SUPERFAMILY SSF50685 381 423 1.95E-8 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CXR48_RS00265 ff0df107b0a2afcbddb1074576a970a2 441 Pfam PF07501 G5 domain 250 322 5.5E-19 T 29-03-2018 IPR011098 G5 domain CXR48_RS00265 ff0df107b0a2afcbddb1074576a970a2 441 Pfam PF03990 Domain of unknown function (DUF348) 191 230 1.9E-12 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CXR48_RS00265 ff0df107b0a2afcbddb1074576a970a2 441 Pfam PF03990 Domain of unknown function (DUF348) 77 115 3.9E-11 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CXR48_RS00265 ff0df107b0a2afcbddb1074576a970a2 441 Pfam PF03990 Domain of unknown function (DUF348) 137 174 1.2E-8 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CXR48_RS00265 ff0df107b0a2afcbddb1074576a970a2 441 SMART SM01208 245 323 5.5E-25 T 29-03-2018 IPR011098 G5 domain CXR48_RS00265 ff0df107b0a2afcbddb1074576a970a2 441 Gene3D G3DSA:2.40.40.10 242 440 8.5E-42 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CXR48_RS00265 ff0df107b0a2afcbddb1074576a970a2 441 Pfam PF06725 3D domain 380 441 1.5E-20 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CXR48_RS08675 2ae9a999c65d94df4e1f61d9151d6a36 329 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 96 113 - T 29-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08675 2ae9a999c65d94df4e1f61d9151d6a36 329 PIRSF PIRSF000355 1 319 5.1E-96 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08675 2ae9a999c65d94df4e1f61d9151d6a36 329 Gene3D G3DSA:1.10.620.20 4 296 8.9E-73 T 29-03-2018 CXR48_RS08675 2ae9a999c65d94df4e1f61d9151d6a36 329 SUPERFAMILY SSF47240 4 322 5.35E-92 T 29-03-2018 IPR009078 Ferritin-like superfamily CXR48_RS08675 2ae9a999c65d94df4e1f61d9151d6a36 329 Pfam PF00268 Ribonucleotide reductase, small chain 8 284 1.5E-81 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CXR48_RS08675 2ae9a999c65d94df4e1f61d9151d6a36 329 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 5 322 1.7E-146 T 29-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CXR48_RS09970 bc66e1a154ce5f4d1cfb1bac887b11fa 555 SUPERFAMILY SSF53041 15 167 1.44E-16 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CXR48_RS09970 bc66e1a154ce5f4d1cfb1bac887b11fa 555 Pfam PF00239 Resolvase, N terminal domain 16 167 6.4E-15 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CXR48_RS09970 bc66e1a154ce5f4d1cfb1bac887b11fa 555 SMART SM00857 15 167 4.7E-14 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CXR48_RS09970 bc66e1a154ce5f4d1cfb1bac887b11fa 555 Pfam PF07508 Recombinase 189 298 6.9E-21 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CXR48_RS09970 bc66e1a154ce5f4d1cfb1bac887b11fa 555 Gene3D G3DSA:3.40.50.1390 11 176 5.5E-23 T 29-03-2018 CXR48_RS07840 9e459a7239a8ab5c851c1ab7e69cde1b 317 SUPERFAMILY SSF50486 205 310 5.97E-35 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CXR48_RS07840 9e459a7239a8ab5c851c1ab7e69cde1b 317 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 305 37.32 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CXR48_RS07840 9e459a7239a8ab5c851c1ab7e69cde1b 317 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 2.5E-33 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS07840 9e459a7239a8ab5c851c1ab7e69cde1b 317 Gene3D G3DSA:3.40.50.170 1 206 5.6E-71 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS07840 9e459a7239a8ab5c851c1ab7e69cde1b 317 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS07840 9e459a7239a8ab5c851c1ab7e69cde1b 317 SUPERFAMILY SSF53328 3 206 7.46E-68 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS07840 9e459a7239a8ab5c851c1ab7e69cde1b 317 Gene3D G3DSA:3.10.25.10 207 311 3.2E-35 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS07840 9e459a7239a8ab5c851c1ab7e69cde1b 317 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 308 6.3E-122 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CXR48_RS07840 9e459a7239a8ab5c851c1ab7e69cde1b 317 Pfam PF00551 Formyl transferase 3 180 4.4E-39 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 SUPERFAMILY SSF103473 493 520 1.57E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 SUPERFAMILY SSF103473 253 424 1.57E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 SUPERFAMILY SSF103473 13 199 1.57E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 424 2.0E-82 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 Gene3D G3DSA:1.20.1250.20 257 528 3.4E-32 T 29-03-2018 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 Pfam PF07690 Major Facilitator Superfamily 23 414 7.9E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 88 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 2.2E-13 T 29-03-2018 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 405 424 2.2E-13 T 29-03-2018 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 307 331 2.2E-13 T 29-03-2018 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 2.2E-13 T 29-03-2018 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 2.2E-13 T 29-03-2018 CXR48_RS15365 7b3c088bde97d16ceeb0f1bb8fe226aa 541 Gene3D G3DSA:1.20.1250.20 13 199 1.2E-31 T 29-03-2018 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 SUPERFAMILY SSF103473 8 398 1.7E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 Gene3D G3DSA:1.20.1250.20 202 410 7.2E-18 T 29-03-2018 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 Pfam PF01306 LacY proton/sugar symporter 5 398 1.3E-141 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 Gene3D G3DSA:1.20.1250.20 4 201 8.3E-18 T 29-03-2018 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 TIGRFAM TIGR00882 2A0105: oligosaccharide:H+ symporter 7 393 4.1E-142 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 PRINTS PR00174 LacY proton/sugar symporter family signature 102 124 1.2E-88 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 PRINTS PR00174 LacY proton/sugar symporter family signature 308 327 1.2E-88 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 PRINTS PR00174 LacY proton/sugar symporter family signature 67 96 1.2E-88 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 PRINTS PR00174 LacY proton/sugar symporter family signature 253 274 1.2E-88 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 PRINTS PR00174 LacY proton/sugar symporter family signature 277 303 1.2E-88 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 PRINTS PR00174 LacY proton/sugar symporter family signature 207 235 1.2E-88 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 PRINTS PR00174 LacY proton/sugar symporter family signature 144 162 1.2E-88 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS16295 740cda3b3bad0414a02d57f6b1019240 410 PRINTS PR00174 LacY proton/sugar symporter family signature 339 359 1.2E-88 T 29-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 CXR48_RS18345 18c0400b6b0f34013302649c165aa455 314 Gene3D G3DSA:2.60.120.10 1 223 1.6E-63 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS18345 18c0400b6b0f34013302649c165aa455 314 PIRSF PIRSF036894 2 312 1.6E-128 T 29-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CXR48_RS18345 18c0400b6b0f34013302649c165aa455 314 Gene3D G3DSA:2.60.120.10 238 311 4.4E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS18345 18c0400b6b0f34013302649c165aa455 314 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 101 310 3.4E-48 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CXR48_RS18345 18c0400b6b0f34013302649c165aa455 314 Pfam PF01238 Phosphomannose isomerase type I 5 197 3.7E-39 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CXR48_RS18345 18c0400b6b0f34013302649c165aa455 314 SUPERFAMILY SSF51182 1 310 1.96E-107 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS04365 722cdf7e1904f219f00643f4c90cca68 318 SUPERFAMILY SSF161098 89 303 2.49E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS04365 722cdf7e1904f219f00643f4c90cca68 318 Gene3D G3DSA:1.10.3720.10 1 305 1.4E-47 T 29-03-2018 CXR48_RS04365 722cdf7e1904f219f00643f4c90cca68 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 316 5.2E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS17970 6d59ff74a556131aeaccc646b34c1785 268 Gene3D G3DSA:3.90.550.10 2 231 2.4E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS17970 6d59ff74a556131aeaccc646b34c1785 268 SUPERFAMILY SSF53448 3 206 9.21E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS17970 6d59ff74a556131aeaccc646b34c1785 268 Pfam PF00535 Glycosyl transferase family 2 4 162 8.2E-30 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS13090 f299871a9e93dd9e3cd2ae339c2a648d 245 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 5.4E-23 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS13090 f299871a9e93dd9e3cd2ae339c2a648d 245 SUPERFAMILY SSF55666 154 237 3.01E-23 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS13090 f299871a9e93dd9e3cd2ae339c2a648d 245 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 1.2E-115 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CXR48_RS13090 f299871a9e93dd9e3cd2ae339c2a648d 245 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site CXR48_RS13090 f299871a9e93dd9e3cd2ae339c2a648d 245 SUPERFAMILY SSF54211 1 182 1.06E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS13090 f299871a9e93dd9e3cd2ae339c2a648d 245 Hamap MF_00564 Ribonuclease PH [rph]. 1 238 47.717 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CXR48_RS13090 f299871a9e93dd9e3cd2ae339c2a648d 245 Pfam PF03725 3' exoribonuclease family, domain 2 159 225 1.2E-8 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS13090 f299871a9e93dd9e3cd2ae339c2a648d 245 Gene3D G3DSA:3.30.230.70 1 241 2.9E-56 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CXR48_RS01935 0752994d7383f4590b6cade9df51ecf3 227 Pfam PF00072 Response regulator receiver domain 3 112 3.6E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS01935 0752994d7383f4590b6cade9df51ecf3 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 224 4.5E-29 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS01935 0752994d7383f4590b6cade9df51ecf3 227 SMART SM00448 1 111 7.0E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS01935 0752994d7383f4590b6cade9df51ecf3 227 Gene3D G3DSA:1.10.10.10 124 227 1.2E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01935 0752994d7383f4590b6cade9df51ecf3 227 SMART SM00862 149 224 2.5E-30 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS01935 0752994d7383f4590b6cade9df51ecf3 227 SUPERFAMILY SSF52172 1 124 2.99E-39 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS01935 0752994d7383f4590b6cade9df51ecf3 227 Gene3D G3DSA:3.40.50.2300 1 123 6.4E-34 T 29-03-2018 CXR48_RS01935 0752994d7383f4590b6cade9df51ecf3 227 SUPERFAMILY SSF46894 128 225 3.4E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS06255 a469d2f26562f0d74d6edff18729f839 127 SUPERFAMILY SSF116915 1 114 1.09E-40 T 29-03-2018 IPR013514 Protein of unknown function DUF3199, YqbG CXR48_RS06255 a469d2f26562f0d74d6edff18729f839 127 Pfam PF11436 Protein of unknown function (DUF3199) 2 125 5.9E-48 T 29-03-2018 IPR013514 Protein of unknown function DUF3199, YqbG CXR48_RS06255 a469d2f26562f0d74d6edff18729f839 127 Gene3D G3DSA:1.10.3230.10 1 127 6.9E-34 T 29-03-2018 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 SUPERFAMILY SSF55811 229 359 1.07E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 Gene3D G3DSA:1.10.340.30 30 133 1.7E-30 T 29-03-2018 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 Pfam PF14815 NUDIX domain 244 357 1.8E-24 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 SUPERFAMILY SSF48150 13 231 1.11E-70 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 SMART SM00525 200 220 0.0012 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 Gene3D G3DSA:1.10.1670.10 134 237 4.0E-34 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 15 282 2.8E-116 T 29-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 SMART SM00478 48 199 3.4E-51 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 Gene3D G3DSA:3.90.79.10 240 364 1.3E-16 T 29-03-2018 CXR48_RS04175 712154866d6afab91ba8e4c255defefe 364 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 175 2.3E-20 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SUPERFAMILY SSF55021 657 734 4.08E-12 T 29-03-2018 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Pfam PF13328 HD domain 31 180 1.3E-50 T 29-03-2018 IPR003607 HD/PDEase domain CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Gene3D G3DSA:3.30.460.10 193 331 2.9E-46 T 29-03-2018 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SUPERFAMILY SSF81271 381 453 1.4E-22 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 731 1.4E-258 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 3.2E-39 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SMART SM00954 240 350 3.0E-70 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Pfam PF02824 TGS domain 394 453 4.2E-23 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Gene3D G3DSA:3.30.70.260 654 734 3.3E-10 T 29-03-2018 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SMART SM00471 46 158 3.0E-8 T 29-03-2018 IPR003607 HD/PDEase domain CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Pfam PF13291 ACT domain 655 731 4.6E-20 T 29-03-2018 IPR002912 ACT domain CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Gene3D G3DSA:3.10.20.30 388 461 3.0E-24 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SUPERFAMILY SSF81301 185 398 7.19E-67 T 29-03-2018 CXR48_RS12720 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SUPERFAMILY SSF109604 10 196 4.39E-76 T 29-03-2018 CXR48_RS05305 cb5b274f06fc98a2718ed0be3c950335 131 Pfam PF10970 Spore germination protein GerPE 5 127 5.9E-45 T 29-03-2018 IPR024496 Spore germination protein GerPE CXR48_RS05305 cb5b274f06fc98a2718ed0be3c950335 131 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 5 120 5.0E-43 T 29-03-2018 IPR024496 Spore germination protein GerPE CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 579 2.4E-40 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 2.0E-6 T 29-03-2018 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.0E-6 T 29-03-2018 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 Pfam PF00890 FAD binding domain 6 392 1.3E-86 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.4E-8 T 29-03-2018 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 5.4E-8 T 29-03-2018 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 SUPERFAMILY SSF51905 357 425 1.11E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 SUPERFAMILY SSF51905 6 247 1.11E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 Gene3D G3DSA:4.10.80.40 548 579 5.0E-4 T 29-03-2018 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 SUPERFAMILY SSF46977 443 579 2.62E-44 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 Gene3D G3DSA:3.50.50.60 3 445 4.2E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 579 1.0E-282 T 29-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 Gene3D G3DSA:1.20.58.100 446 547 2.9E-26 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 SUPERFAMILY SSF56425 231 353 3.74E-31 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 PIRSF PIRSF000171 343 574 3.7E-16 T 29-03-2018 CXR48_RS13125 4cc4ce8c175634aebfd38c534e0d3080 586 PIRSF PIRSF000171 1 240 1.5E-20 T 29-03-2018 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 SUPERFAMILY SSF52418 69 329 9.42E-94 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 1.6E-28 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 1.9E-184 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 Gene3D G3DSA:1.20.970.10 1 67 3.3E-25 T 29-03-2018 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 Gene3D G3DSA:3.90.1170.30 338 423 1.4E-29 T 29-03-2018 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 Gene3D G3DSA:3.40.1030.10 68 337 3.4E-96 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 SMART SM00941 345 418 9.9E-33 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 2.1E-20 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 SUPERFAMILY SSF54680 331 431 3.01E-30 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 SUPERFAMILY SSF47648 1 69 4.71E-22 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 2.4E-51 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS18605 36876484ce686b09631c2a7fdf7fd43f 433 PIRSF PIRSF000478 1 433 1.9E-173 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS05695 88c8970e816f1e47e173a23a136bd1ee 211 Gene3D G3DSA:1.10.287.860 148 196 7.3E-20 T 29-03-2018 CXR48_RS05695 88c8970e816f1e47e173a23a136bd1ee 211 Gene3D G3DSA:3.30.460.10 1 146 5.3E-36 T 29-03-2018 CXR48_RS05695 88c8970e816f1e47e173a23a136bd1ee 211 Pfam PF04607 Region found in RelA / SpoT proteins 45 163 6.0E-37 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CXR48_RS05695 88c8970e816f1e47e173a23a136bd1ee 211 SUPERFAMILY SSF81301 5 198 7.36E-59 T 29-03-2018 CXR48_RS05695 88c8970e816f1e47e173a23a136bd1ee 211 SMART SM00954 45 165 1.9E-40 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 527 1.7E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 SUPERFAMILY SSF55890 326 392 3.4E-9 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 487 2.9E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 2.9E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 2.9E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 2.9E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 Pfam PF17203 Single cache domain 3 43 174 9.3E-8 T 29-03-2018 IPR033463 Single cache domain 3 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 SMART SM00387 420 528 5.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 SMART SM00091 216 281 0.0038 T 29-03-2018 IPR000014 PAS domain CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 Gene3D G3DSA:3.30.450.20 207 322 6.3E-9 T 29-03-2018 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 323 370 1.1E-8 T 29-03-2018 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 Gene3D G3DSA:3.30.565.10 375 529 5.6E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 SUPERFAMILY SSF103190 41 167 5.1E-15 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 Gene3D G3DSA:1.10.287.130 323 374 6.8E-15 T 29-03-2018 CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 SUPERFAMILY SSF55785 222 309 3.89E-7 T 29-03-2018 IPR000014 PAS domain CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 SUPERFAMILY SSF55874 397 526 3.67E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS03715 0200222d6ee876c6c962ae44cf409728 534 Gene3D G3DSA:3.30.450.20 35 167 2.2E-10 T 29-03-2018 CXR48_RS00405 6f4cd4030b06dcf29cca660876eba22b 333 SUPERFAMILY SSF56112 17 235 3.01E-24 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS00405 6f4cd4030b06dcf29cca660876eba22b 333 Gene3D G3DSA:3.30.200.20 13 102 5.3E-9 T 29-03-2018 CXR48_RS00405 6f4cd4030b06dcf29cca660876eba22b 333 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 34 55 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CXR48_RS00405 6f4cd4030b06dcf29cca660876eba22b 333 Pfam PF00069 Protein kinase domain 28 235 1.2E-14 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CXR48_RS00405 6f4cd4030b06dcf29cca660876eba22b 333 Gene3D G3DSA:1.10.510.10 103 292 1.2E-13 T 29-03-2018 CXR48_RS00405 6f4cd4030b06dcf29cca660876eba22b 333 SMART SM00220 28 265 3.1E-6 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CXR48_RS07935 81db0323fe16cec9cf2e3c94d4d5dd0a 77 Gene3D G3DSA:1.10.1200.10 1 77 5.7E-25 T 29-03-2018 CXR48_RS07935 81db0323fe16cec9cf2e3c94d4d5dd0a 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.5E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07935 81db0323fe16cec9cf2e3c94d4d5dd0a 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 77 2.4E-35 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CXR48_RS07935 81db0323fe16cec9cf2e3c94d4d5dd0a 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 55 76 2.0E-5 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CXR48_RS07935 81db0323fe16cec9cf2e3c94d4d5dd0a 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.652 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CXR48_RS07935 81db0323fe16cec9cf2e3c94d4d5dd0a 77 SUPERFAMILY SSF47336 2 76 4.45E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS07935 81db0323fe16cec9cf2e3c94d4d5dd0a 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS14105 83a4ebf0d9649febef5bdb0c9f71efe2 269 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 35 259 6.5E-38 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CXR48_RS14105 83a4ebf0d9649febef5bdb0c9f71efe2 269 SUPERFAMILY SSF51695 29 265 4.45E-55 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CXR48_RS14105 83a4ebf0d9649febef5bdb0c9f71efe2 269 Gene3D G3DSA:3.20.20.190 16 269 1.4E-59 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CXR48_RS11930 df9d3ef877de3dfd17ca08f5a84cf32b 345 Gene3D G3DSA:2.140.10.30 136 329 1.8E-4 T 29-03-2018 CXR48_RS11930 df9d3ef877de3dfd17ca08f5a84cf32b 345 Gene3D G3DSA:2.140.10.30 22 135 2.2E-4 T 29-03-2018 CXR48_RS11930 df9d3ef877de3dfd17ca08f5a84cf32b 345 SUPERFAMILY SSF69304 274 325 1.06E-9 T 29-03-2018 CXR48_RS11930 df9d3ef877de3dfd17ca08f5a84cf32b 345 SUPERFAMILY SSF69304 55 233 1.06E-9 T 29-03-2018 CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 Gene3D G3DSA:1.25.40.10 187 247 0.28 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 Gene3D G3DSA:1.25.40.10 248 289 1.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 Gene3D G3DSA:1.20.58.280 290 321 0.001 T 29-03-2018 CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 SUPERFAMILY SSF53448 8 106 2.25E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 SUPERFAMILY SSF48452 205 359 7.21E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 SMART SM00028 245 278 5.4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 SMART SM00028 279 312 0.11 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 SMART SM00028 324 357 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 Pfam PF00535 Glycosyl transferase family 2 11 95 1.6E-20 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 Gene3D G3DSA:3.90.550.10 8 174 1.1E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS06540 39698fe56ed563523c124c614e7d642b 375 Gene3D G3DSA:1.25.40.10 322 374 2.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS04490 0aeb0a00f57cbd8b3bf062937328aba4 221 Gene3D G3DSA:2.40.50.100 57 93 3.5E-5 T 29-03-2018 CXR48_RS04490 0aeb0a00f57cbd8b3bf062937328aba4 221 Gene3D G3DSA:1.20.1600.10 94 219 1.7E-10 T 29-03-2018 CXR48_RS04490 0aeb0a00f57cbd8b3bf062937328aba4 221 SUPERFAMILY SSF51230 50 122 4.71E-10 T 29-03-2018 IPR011053 Single hybrid motif CXR48_RS04490 0aeb0a00f57cbd8b3bf062937328aba4 221 Pfam PF13437 HlyD family secretion protein 96 212 2.7E-15 T 29-03-2018 CXR48_RS12870 49cbb6cc7d2c290ad45239355efc9a22 113 SUPERFAMILY SSF118010 1 109 7.72E-29 T 29-03-2018 IPR007422 Cysteine protease Prp CXR48_RS12870 49cbb6cc7d2c290ad45239355efc9a22 113 Gene3D G3DSA:3.30.70.1490 2 112 7.0E-28 T 29-03-2018 IPR007422 Cysteine protease Prp CXR48_RS12870 49cbb6cc7d2c290ad45239355efc9a22 113 Pfam PF04327 Cysteine protease Prp 1 106 1.5E-23 T 29-03-2018 IPR007422 Cysteine protease Prp CXR48_RS14715 8f6dcc64585df2fa91a3b08e45b48e1a 143 TIGRFAM TIGR00943 2a6301s02: monovalent cation:proton antiporter 29 135 2.7E-44 T 29-03-2018 IPR005281 Monovalent cation:proton antiporter, subunit B GO:0006812|GO:0008324|GO:0016021 CXR48_RS14715 8f6dcc64585df2fa91a3b08e45b48e1a 143 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 10 134 4.3E-36 T 29-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CXR48_RS17330 4cf448b6fef1d19a61b76b71ac7f83be 105 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 6.0E-44 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17330 4cf448b6fef1d19a61b76b71ac7f83be 105 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 102 1.2E-55 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17330 4cf448b6fef1d19a61b76b71ac7f83be 105 PIRSF PIRSF001223 1 100 2.2E-49 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17330 4cf448b6fef1d19a61b76b71ac7f83be 105 Gene3D G3DSA:3.30.280.10 2 99 2.6E-45 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17330 4cf448b6fef1d19a61b76b71ac7f83be 105 Pfam PF00547 Urease, gamma subunit 1 99 7.7E-45 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17330 4cf448b6fef1d19a61b76b71ac7f83be 105 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.364 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17330 4cf448b6fef1d19a61b76b71ac7f83be 105 SUPERFAMILY SSF54111 1 101 9.03E-44 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS05355 7adaf5b07c5072a4e88a35ca688624ff 613 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 532 3.1E-177 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CXR48_RS05355 7adaf5b07c5072a4e88a35ca688624ff 613 Pfam PF00733 Asparagine synthase 242 604 2.1E-98 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CXR48_RS05355 7adaf5b07c5072a4e88a35ca688624ff 613 Pfam PF13537 Glutamine amidotransferase domain 48 169 2.5E-47 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CXR48_RS05355 7adaf5b07c5072a4e88a35ca688624ff 613 Gene3D G3DSA:3.40.50.620 227 583 1.6E-65 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS05355 7adaf5b07c5072a4e88a35ca688624ff 613 Gene3D G3DSA:3.60.20.10 1 226 1.2E-55 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS05355 7adaf5b07c5072a4e88a35ca688624ff 613 SUPERFAMILY SSF56235 1 226 1.63E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS05355 7adaf5b07c5072a4e88a35ca688624ff 613 PIRSF PIRSF001589 1 610 2.5E-148 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CXR48_RS05355 7adaf5b07c5072a4e88a35ca688624ff 613 SUPERFAMILY SSF52402 231 396 3.89E-74 T 29-03-2018 CXR48_RS05355 7adaf5b07c5072a4e88a35ca688624ff 613 SUPERFAMILY SSF52402 452 576 3.89E-74 T 29-03-2018 CXR48_RS02485 7dba04c8e4073ad72ed29923d5552934 149 Pfam PF10263 SprT-like family 8 97 3.6E-12 T 29-03-2018 IPR006640 SprT-like CXR48_RS02485 7dba04c8e4073ad72ed29923d5552934 149 SMART SM00731 4 148 1.1E-58 T 29-03-2018 IPR006640 SprT-like CXR48_RS02485 7dba04c8e4073ad72ed29923d5552934 149 Hamap MF_00745 Protein SprT-like. 4 148 39.836 T 29-03-2018 IPR023524 Uncharacterised protein family SprT-like CXR48_RS00310 bc47bad435befc045fe4086f82c274e4 97 Pfam PF04026 SpoVG 2 81 3.4E-35 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CXR48_RS00310 bc47bad435befc045fe4086f82c274e4 97 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 94 27.823 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CXR48_RS00310 bc47bad435befc045fe4086f82c274e4 97 SUPERFAMILY SSF160537 2 84 6.15E-33 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CXR48_RS00310 bc47bad435befc045fe4086f82c274e4 97 Gene3D G3DSA:3.30.1120.40 1 83 1.5E-35 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CXR48_RS17200 42ad676371cc7344b2b63fe4f1346b2c 354 Gene3D G3DSA:1.25.40.10 181 354 3.2E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17200 42ad676371cc7344b2b63fe4f1346b2c 354 Gene3D G3DSA:1.25.40.10 1 134 5.2E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17200 42ad676371cc7344b2b63fe4f1346b2c 354 SUPERFAMILY SSF48452 80 279 2.09E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17200 42ad676371cc7344b2b63fe4f1346b2c 354 SMART SM00028 130 163 22.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17200 42ad676371cc7344b2b63fe4f1346b2c 354 SMART SM00028 171 204 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17200 42ad676371cc7344b2b63fe4f1346b2c 354 SMART SM00028 211 244 31.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17200 42ad676371cc7344b2b63fe4f1346b2c 354 Pfam PF13424 Tetratricopeptide repeat 176 238 1.3E-7 T 29-03-2018 CXR48_RS17200 42ad676371cc7344b2b63fe4f1346b2c 354 Gene3D G3DSA:1.25.40.10 135 180 0.011 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS04450 1507f49e41fc1cc8c7ed5591f75d0885 160 Pfam PF00588 SpoU rRNA Methylase family 6 148 6.4E-34 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CXR48_RS04450 1507f49e41fc1cc8c7ed5591f75d0885 160 PIRSF PIRSF029256 5 160 1.2E-68 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CXR48_RS04450 1507f49e41fc1cc8c7ed5591f75d0885 160 SUPERFAMILY SSF75217 6 158 3.6E-45 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CXR48_RS04450 1507f49e41fc1cc8c7ed5591f75d0885 160 Gene3D G3DSA:3.40.1280.10 4 160 1.0E-42 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CXR48_RS04450 1507f49e41fc1cc8c7ed5591f75d0885 160 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 6 157 34.549 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CXR48_RS04450 1507f49e41fc1cc8c7ed5591f75d0885 160 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 5 159 9.7E-73 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CXR48_RS17740 7606b2633eb0fa78a0c5af38dfbeb43e 62 Gene3D G3DSA:3.30.429.10 2 62 8.4E-19 T 29-03-2018 CXR48_RS17740 7606b2633eb0fa78a0c5af38dfbeb43e 62 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 61 5.8E-29 T 29-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CXR48_RS17740 7606b2633eb0fa78a0c5af38dfbeb43e 62 SUPERFAMILY SSF55331 2 60 8.38E-18 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CXR48_RS17740 7606b2633eb0fa78a0c5af38dfbeb43e 62 Pfam PF01361 Tautomerase enzyme 2 60 5.1E-22 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CXR48_RS06950 ddfd98f92a942366d446393aa3595393 287 Pfam PF00149 Calcineurin-like phosphoesterase 58 223 3.9E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CXR48_RS06950 ddfd98f92a942366d446393aa3595393 287 Gene3D G3DSA:3.60.21.10 55 285 1.0E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS06950 ddfd98f92a942366d446393aa3595393 287 SUPERFAMILY SSF56300 55 283 2.95E-35 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS02580 2b80cc3c7c1304499bfc91b42dddbff9 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CXR48_RS02580 2b80cc3c7c1304499bfc91b42dddbff9 67 PIRSF PIRSF002599 1 67 5.3E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CXR48_RS02580 2b80cc3c7c1304499bfc91b42dddbff9 67 Gene3D G3DSA:2.40.50.140 1 66 2.5E-29 T 29-03-2018 CXR48_RS02580 2b80cc3c7c1304499bfc91b42dddbff9 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.8E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS02580 2b80cc3c7c1304499bfc91b42dddbff9 67 PRINTS PR00050 Cold shock protein signature 39 57 2.6E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS02580 2b80cc3c7c1304499bfc91b42dddbff9 67 PRINTS PR00050 Cold shock protein signature 24 33 2.6E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS02580 2b80cc3c7c1304499bfc91b42dddbff9 67 PRINTS PR00050 Cold shock protein signature 4 19 2.6E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CXR48_RS02580 2b80cc3c7c1304499bfc91b42dddbff9 67 SUPERFAMILY SSF50249 1 65 3.26E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS02580 2b80cc3c7c1304499bfc91b42dddbff9 67 SMART SM00357 3 66 4.2E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 PIRSF PIRSF000183 1 370 4.2E-195 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 139 351 2.8E-83 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 29-03-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.3E-198 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 SMART SM01003 4 135 2.9E-81 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 Gene3D G3DSA:3.50.50.60 176 193 0.04 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 171 196 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 SUPERFAMILY SSF52283 1 135 1.11E-68 T 29-03-2018 CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 SUPERFAMILY SSF52283 304 359 1.11E-68 T 29-03-2018 CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 SUPERFAMILY SSF51735 135 302 5.42E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 135 6.9E-49 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 SMART SM01002 147 296 2.4E-87 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 Gene3D G3DSA:3.40.50.720 1 175 5.1E-47 T 29-03-2018 CXR48_RS14865 02e31b95147e9b275c2b68f661f0b43e 376 Gene3D G3DSA:3.40.50.720 194 370 4.5E-45 T 29-03-2018 CXR48_RS18960 301060b7d80111efebc39986dfc80a7b 95 SMART SM00418 3 81 3.0E-28 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18960 301060b7d80111efebc39986dfc80a7b 95 Gene3D G3DSA:1.10.10.10 1 77 3.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18960 301060b7d80111efebc39986dfc80a7b 95 Pfam PF01022 Bacterial regulatory protein, arsR family 10 55 3.9E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18960 301060b7d80111efebc39986dfc80a7b 95 SUPERFAMILY SSF46785 3 83 4.4E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18960 301060b7d80111efebc39986dfc80a7b 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 5.1E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18960 301060b7d80111efebc39986dfc80a7b 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 5.1E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18960 301060b7d80111efebc39986dfc80a7b 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 5.1E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18970 03b51325ab7dd10c74b2fee6c53d1251 239 SMART SM00558 95 238 1.5E-13 T 29-03-2018 IPR003347 JmjC domain CXR48_RS18970 03b51325ab7dd10c74b2fee6c53d1251 239 Pfam PF13621 Cupin-like domain 20 231 4.1E-26 T 29-03-2018 CXR48_RS18970 03b51325ab7dd10c74b2fee6c53d1251 239 SUPERFAMILY SSF51197 11 230 1.08E-49 T 29-03-2018 CXR48_RS18970 03b51325ab7dd10c74b2fee6c53d1251 239 Gene3D G3DSA:2.60.120.650 3 231 4.0E-43 T 29-03-2018 CXR48_RS01690 1269b053d8fa21a1150f9ca2023274f4 261 Gene3D G3DSA:3.30.460.10 1 119 2.0E-5 T 29-03-2018 CXR48_RS01690 1269b053d8fa21a1150f9ca2023274f4 261 Pfam PF10127 Predicted nucleotidyltransferase 1 249 5.7E-90 T 29-03-2018 IPR018775 Nucleotidyltransferase, predicted CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 SUPERFAMILY SSF56059 135 353 8.49E-65 T 29-03-2018 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 348 42.239 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 Gene3D G3DSA:3.30.1490.20 150 210 1.9E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 PIRSF PIRSF039102 1 356 3.5E-117 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 290 318 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 Gene3D G3DSA:3.30.470.20 211 357 2.2E-47 T 29-03-2018 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 SUPERFAMILY SSF52440 2 134 3.55E-35 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 102 113 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 Pfam PF01820 D-ala D-ala ligase N-terminus 5 124 1.5E-30 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 347 1.1E-122 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 Pfam PF07478 D-ala D-ala ligase C-terminus 142 345 3.6E-86 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02380 28d94979af32ae31e1652bf0e60e131b 361 Gene3D G3DSA:3.40.50.20 1 145 1.5E-43 T 29-03-2018 CXR48_RS14410 cdffa26a69ae87a8c054a01f019fa7b7 162 Gene3D G3DSA:1.20.120.450 1 161 1.5E-31 T 29-03-2018 CXR48_RS14410 cdffa26a69ae87a8c054a01f019fa7b7 162 Pfam PF12867 DinB superfamily 4 152 6.2E-23 T 29-03-2018 IPR024775 DinB-like domain CXR48_RS14410 cdffa26a69ae87a8c054a01f019fa7b7 162 SUPERFAMILY SSF109854 2 158 2.75E-30 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CXR48_RS15105 94806065662fdcd9140f2bc33fb43663 298 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 293 2.7E-120 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CXR48_RS15105 94806065662fdcd9140f2bc33fb43663 298 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 148.407 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CXR48_RS15105 94806065662fdcd9140f2bc33fb43663 298 PIRSF PIRSF005963 1 298 2.7E-135 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CXR48_RS15105 94806065662fdcd9140f2bc33fb43663 298 SUPERFAMILY SSF102114 20 287 4.97E-63 T 29-03-2018 CXR48_RS15105 94806065662fdcd9140f2bc33fb43663 298 Pfam PF04055 Radical SAM superfamily 64 224 1.5E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS15105 94806065662fdcd9140f2bc33fb43663 298 Gene3D G3DSA:3.20.20.70 2 267 7.0E-26 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS15105 94806065662fdcd9140f2bc33fb43663 298 SMART SM00729 57 265 7.2E-16 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CXR48_RS15105 94806065662fdcd9140f2bc33fb43663 298 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 3 45 1.0E-11 T 29-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CXR48_RS00805 dc468fcc1e00d40f1e3ed51c8736fca2 132 Gene3D G3DSA:3.30.1490.10 69 130 3.3E-23 T 29-03-2018 CXR48_RS00805 dc468fcc1e00d40f1e3ed51c8736fca2 132 Pfam PF00410 Ribosomal protein S8 5 132 1.7E-55 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00805 dc468fcc1e00d40f1e3ed51c8736fca2 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.253 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00805 dc468fcc1e00d40f1e3ed51c8736fca2 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00805 dc468fcc1e00d40f1e3ed51c8736fca2 132 Gene3D G3DSA:3.30.1370.30 1 67 2.5E-28 T 29-03-2018 CXR48_RS00805 dc468fcc1e00d40f1e3ed51c8736fca2 132 SUPERFAMILY SSF56047 2 132 1.57E-50 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS10120 acbc5a663c13ef965f37beb69c51166a 130 SUPERFAMILY SSF53098 3 123 1.39E-27 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS10120 acbc5a663c13ef965f37beb69c51166a 130 Pfam PF13456 Reverse transcriptase-like 7 125 4.6E-18 T 29-03-2018 CXR48_RS10120 acbc5a663c13ef965f37beb69c51166a 130 Gene3D G3DSA:3.30.420.10 2 130 9.1E-26 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS01625 64541284de03a4573884c4700f31972f 510 SUPERFAMILY SSF103473 12 202 1.83E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01625 64541284de03a4573884c4700f31972f 510 SUPERFAMILY SSF103473 249 419 1.83E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01625 64541284de03a4573884c4700f31972f 510 SUPERFAMILY SSF103473 471 502 1.83E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01625 64541284de03a4573884c4700f31972f 510 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 493 1.7E-87 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CXR48_RS01625 64541284de03a4573884c4700f31972f 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 302 326 6.4E-5 T 29-03-2018 CXR48_RS01625 64541284de03a4573884c4700f31972f 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 76 98 6.4E-5 T 29-03-2018 CXR48_RS01625 64541284de03a4573884c4700f31972f 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 6.4E-5 T 29-03-2018 CXR48_RS01625 64541284de03a4573884c4700f31972f 510 Gene3D G3DSA:1.20.1250.20 252 510 1.7E-32 T 29-03-2018 CXR48_RS01625 64541284de03a4573884c4700f31972f 510 Pfam PF07690 Major Facilitator Superfamily 18 409 7.7E-57 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS01625 64541284de03a4573884c4700f31972f 510 Gene3D G3DSA:1.20.1250.20 7 203 5.5E-40 T 29-03-2018 CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 Gene3D G3DSA:3.40.50.970 153 528 5.9E-80 T 29-03-2018 CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 16 939 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 SUPERFAMILY SSF52518 150 530 3.09E-72 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 2 942 23.735 T 29-03-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 SUPERFAMILY SSF52518 577 798 1.47E-42 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 PIRSF PIRSF000157 1 942 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 Gene3D G3DSA:3.40.50.970 594 804 9.2E-50 T 29-03-2018 CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 Pfam PF02779 Transketolase, pyrimidine binding domain 594 791 1.7E-57 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 Gene3D G3DSA:1.10.287.1150 68 152 2.6E-9 T 29-03-2018 CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 Pfam PF00676 Dehydrogenase E1 component 220 532 9.7E-95 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 SMART SM00861 595 791 2.9E-42 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CXR48_RS09580 0137153dd1cd5b0a609802d92739d13c 944 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 796 939 1.1E-38 T 29-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CXR48_RS05700 97f6a0cfe5d819e649844ea61f08bdb7 266 Gene3D G3DSA:2.60.200.30 117 240 3.0E-25 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CXR48_RS05700 97f6a0cfe5d819e649844ea61f08bdb7 266 Pfam PF01513 ATP-NAD kinase 32 184 6.5E-24 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CXR48_RS05700 97f6a0cfe5d819e649844ea61f08bdb7 266 Hamap MF_00361 NAD kinase [nadK]. 1 263 23.01 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CXR48_RS05700 97f6a0cfe5d819e649844ea61f08bdb7 266 SUPERFAMILY SSF111331 22 261 7.19E-62 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CXR48_RS05700 97f6a0cfe5d819e649844ea61f08bdb7 266 Gene3D G3DSA:3.40.50.10330 4 116 3.9E-22 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CXR48_RS00185 c21cd78923fe024ba91f873a1d1cd93e 64 Pfam PF10764 Inhibitor of sigma-G Gin 11 55 4.6E-20 T 29-03-2018 IPR019700 Anti-sigma-G factor Gin CXR48_RS12300 ae7318912e1bbf10675714cb6f9855be 204 Gene3D G3DSA:1.10.150.20 146 160 0.19 T 29-03-2018 CXR48_RS12300 ae7318912e1bbf10675714cb6f9855be 204 Pfam PF10531 SLBB domain 67 122 5.0E-14 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS12300 ae7318912e1bbf10675714cb6f9855be 204 Pfam PF12836 Helix-hairpin-helix motif 141 202 9.8E-24 T 29-03-2018 CXR48_RS12300 ae7318912e1bbf10675714cb6f9855be 204 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 139 203 4.2E-30 T 29-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CXR48_RS12300 ae7318912e1bbf10675714cb6f9855be 204 SMART SM00278 181 200 1.2 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS12300 ae7318912e1bbf10675714cb6f9855be 204 SMART SM00278 151 170 0.0055 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS12300 ae7318912e1bbf10675714cb6f9855be 204 SUPERFAMILY SSF47781 128 203 3.78E-29 T 29-03-2018 IPR010994 RuvA domain 2-like CXR48_RS12300 ae7318912e1bbf10675714cb6f9855be 204 Gene3D G3DSA:3.10.560.10 47 145 1.9E-14 T 29-03-2018 CXR48_RS12300 ae7318912e1bbf10675714cb6f9855be 204 Gene3D G3DSA:1.10.150.310 161 204 2.0E-18 T 29-03-2018 CXR48_RS00205 0403a10dbeb786b0ea0acc776aa12d4d 212 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 31.308 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CXR48_RS00205 0403a10dbeb786b0ea0acc776aa12d4d 212 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 197 5.2E-67 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CXR48_RS00205 0403a10dbeb786b0ea0acc776aa12d4d 212 SUPERFAMILY SSF52540 1 210 2.46E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00205 0403a10dbeb786b0ea0acc776aa12d4d 212 Gene3D G3DSA:3.40.50.300 1 211 3.2E-55 T 29-03-2018 CXR48_RS00205 0403a10dbeb786b0ea0acc776aa12d4d 212 Pfam PF02223 Thymidylate kinase 8 197 1.8E-59 T 29-03-2018 CXR48_RS00205 0403a10dbeb786b0ea0acc776aa12d4d 212 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 29-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CXR48_RS12315 6538c7a6e9163c225fb2409832740354 118 Gene3D G3DSA:3.30.460.10 1 108 2.5E-33 T 29-03-2018 CXR48_RS12315 6538c7a6e9163c225fb2409832740354 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 1.4E-37 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CXR48_RS12315 6538c7a6e9163c225fb2409832740354 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 105 25.754 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CXR48_RS12315 6538c7a6e9163c225fb2409832740354 118 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 6.1E-28 T 29-03-2018 CXR48_RS12315 6538c7a6e9163c225fb2409832740354 118 SUPERFAMILY SSF81301 2 113 4.58E-41 T 29-03-2018 CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 Pfam PF13091 PLD-like domain 145 254 1.5E-14 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 SUPERFAMILY SSF56024 113 258 2.07E-11 T 29-03-2018 CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 SMART SM00487 292 479 3.5E-16 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 SUPERFAMILY SSF52540 343 484 3.62E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 SUPERFAMILY SSF52540 512 644 3.62E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 Pfam PF04851 Type III restriction enzyme, res subunit 293 444 3.4E-35 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 Pfam PF00271 Helicase conserved C-terminal domain 533 624 1.7E-9 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 Gene3D G3DSA:3.30.870.10 105 294 7.2E-18 T 29-03-2018 CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 Gene3D G3DSA:3.40.50.300 295 469 1.4E-24 T 29-03-2018 CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 Pfam PF11907 Domain of unknown function (DUF3427) 778 1042 3.1E-59 T 29-03-2018 IPR021835 Protein of unknown function DUF3427 CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 Gene3D G3DSA:3.40.50.300 496 759 7.0E-16 T 29-03-2018 CXR48_RS18560 1ba2f87bc817180fa9ee1e18ecee31ca 1043 SMART SM00490 543 626 6.1E-8 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 Pfam PF08245 Mur ligase middle domain 37 200 4.2E-9 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 TIGRFAM TIGR04012 poly_gGlu_PgsB: poly-gamma-glutamate synthase PgsB 2 383 1.0E-171 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 111 126 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 57 74 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 196 213 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 140 155 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 162 179 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 258 275 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 362 378 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 293 308 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 34 50 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 77 95 1.4E-106 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 Gene3D G3DSA:3.40.1190.10 28 243 4.8E-18 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 SUPERFAMILY SSF53623 33 75 5.23E-18 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS16915 d18a54d45e96fff4adfba2ca9dc4c273 393 SUPERFAMILY SSF53623 104 235 5.23E-18 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 Pfam PF13288 DXP reductoisomerase C-terminal domain 259 375 1.0E-41 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 PIRSF PIRSF006205 1 383 2.1E-161 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 Gene3D G3DSA:3.40.50.720 1 148 1.4E-46 T 29-03-2018 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 SUPERFAMILY SSF69055 290 381 5.23E-30 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 SUPERFAMILY SSF51735 2 148 2.37E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 378 1.7E-178 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 130 2.7E-43 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 381 46.392 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 144 227 6.3E-42 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 SUPERFAMILY SSF55347 125 262 5.23E-60 T 29-03-2018 CXR48_RS08255 6b69b238e0cd7e4c5f97b11b1b7a4606 383 Gene3D G3DSA:1.10.1740.10 301 383 6.0E-29 T 29-03-2018 CXR48_RS04125 296ed1f101bed5af3e1c8c851c78572b 129 Gene3D G3DSA:2.60.40.1120 41 129 3.3E-8 T 29-03-2018 CXR48_RS04125 296ed1f101bed5af3e1c8c851c78572b 129 Pfam PF10794 Protein of unknown function (DUF2606) 1 123 1.0E-27 T 29-03-2018 IPR019730 Protein of unknown function DUF2606 CXR48_RS04125 296ed1f101bed5af3e1c8c851c78572b 129 SUPERFAMILY SSF49452 40 116 8.04E-5 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 3.4E-72 T 29-03-2018 CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 Gene3D G3DSA:3.40.50.720 1 44 2.2E-11 T 29-03-2018 CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 Gene3D G3DSA:3.40.50.720 45 265 7.7E-66 T 29-03-2018 CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 SUPERFAMILY SSF51735 6 256 3.4E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 7.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS18755 4399639379dee46fcfa7159fcd30b720 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS03175 a2be758db07c3b5998207063db4eba69 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CXR48_RS03175 a2be758db07c3b5998207063db4eba69 346 SUPERFAMILY SSF50129 1 178 7.0E-48 T 29-03-2018 IPR011032 GroES-like CXR48_RS03175 a2be758db07c3b5998207063db4eba69 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 138 1.5E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS03175 a2be758db07c3b5998207063db4eba69 346 Pfam PF00107 Zinc-binding dehydrogenase 179 304 1.0E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS03175 a2be758db07c3b5998207063db4eba69 346 SUPERFAMILY SSF51735 143 309 6.41E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS03175 a2be758db07c3b5998207063db4eba69 346 Gene3D G3DSA:3.40.50.720 172 290 1.0E-24 T 29-03-2018 CXR48_RS03175 a2be758db07c3b5998207063db4eba69 346 SMART SM00829 8 343 5.1E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS03175 a2be758db07c3b5998207063db4eba69 346 Gene3D G3DSA:3.90.180.10 1 171 3.0E-46 T 29-03-2018 CXR48_RS04790 3231c451af88f785a3a0b63f59e47f6f 371 SUPERFAMILY SSF50182 181 247 3.27E-18 T 29-03-2018 IPR010920 LSM domain CXR48_RS04790 3231c451af88f785a3a0b63f59e47f6f 371 Gene3D G3DSA:2.30.30.60 197 247 8.7E-17 T 29-03-2018 CXR48_RS04790 3231c451af88f785a3a0b63f59e47f6f 371 SUPERFAMILY SSF82689 248 352 1.83E-18 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CXR48_RS04790 3231c451af88f785a3a0b63f59e47f6f 371 Gene3D G3DSA:3.30.70.100 248 345 1.4E-19 T 29-03-2018 CXR48_RS04790 3231c451af88f785a3a0b63f59e47f6f 371 SUPERFAMILY SSF82861 96 180 1.83E-11 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CXR48_RS04790 3231c451af88f785a3a0b63f59e47f6f 371 Pfam PF00924 Mechanosensitive ion channel 139 341 3.9E-65 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CXR48_RS08620 a832884067d3eb14d6425b2ac85d701b 150 Gene3D G3DSA:3.30.300.20 1 150 2.7E-34 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS08620 a832884067d3eb14d6425b2ac85d701b 150 TIGRFAM TIGR03563 perox_SACOL1771: peroxiredoxin, SACOL1771 subfamily 4 141 2.1E-68 T 29-03-2018 IPR019905 Peroxiredoxin OsmC-like protein, Firmicutes CXR48_RS08620 a832884067d3eb14d6425b2ac85d701b 150 Pfam PF02566 OsmC-like protein 39 142 8.3E-17 T 29-03-2018 IPR003718 OsmC/Ohr family CXR48_RS08620 a832884067d3eb14d6425b2ac85d701b 150 SUPERFAMILY SSF82784 2 145 2.22E-33 T 29-03-2018 IPR003718 OsmC/Ohr family CXR48_RS02140 24281b90a507b639797effca2cbf6095 300 PRINTS PR00069 Aldo-keto reductase signature 143 160 1.3E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS02140 24281b90a507b639797effca2cbf6095 300 PRINTS PR00069 Aldo-keto reductase signature 112 130 1.3E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS02140 24281b90a507b639797effca2cbf6095 300 SUPERFAMILY SSF51430 3 292 5.24E-72 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS02140 24281b90a507b639797effca2cbf6095 300 Gene3D G3DSA:3.20.20.100 1 298 3.7E-64 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS02140 24281b90a507b639797effca2cbf6095 300 Pfam PF00248 Aldo/keto reductase family 15 290 2.1E-58 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS03090 e6fceaa87d0a28d6b053da14fc8c6bf3 152 SUPERFAMILY SSF52980 37 152 4.11E-22 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CXR48_RS03090 e6fceaa87d0a28d6b053da14fc8c6bf3 152 Pfam PF09195 Restriction endonuclease BglII 27 151 1.0E-14 T 29-03-2018 IPR015278 Type-2 restriction enzyme BglII GO:0009036|GO:0009307 CXR48_RS03090 e6fceaa87d0a28d6b053da14fc8c6bf3 152 Gene3D G3DSA:3.40.91.20 12 152 7.4E-26 T 29-03-2018 IPR011338 Restriction endonuclease, type II, BamHI/BglIII/BstY GO:0000287|GO:0003677|GO:0009036|GO:0009307 CXR48_RS06105 6489e65a3e1fecaa2bb7a5b79022dc5b 452 Gene3D G3DSA:1.10.287.130 227 302 4.5E-11 T 29-03-2018 CXR48_RS06105 6489e65a3e1fecaa2bb7a5b79022dc5b 452 SUPERFAMILY SSF47384 227 310 4.71E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06105 6489e65a3e1fecaa2bb7a5b79022dc5b 452 SMART SM00387 354 448 1.3E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06105 6489e65a3e1fecaa2bb7a5b79022dc5b 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 444 9.4E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06105 6489e65a3e1fecaa2bb7a5b79022dc5b 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 308 3.4E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06105 6489e65a3e1fecaa2bb7a5b79022dc5b 452 SUPERFAMILY SSF55874 298 443 3.67E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06105 6489e65a3e1fecaa2bb7a5b79022dc5b 452 SMART SM00388 244 309 5.8E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS06105 6489e65a3e1fecaa2bb7a5b79022dc5b 452 Gene3D G3DSA:3.30.565.10 303 444 4.5E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS05935 79bd08e7402d9135a727dc313e57e516 499 PIRSF PIRSF006005 6 498 7.5E-212 T 29-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05935 79bd08e7402d9135a727dc313e57e516 499 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 13 493 3.4E-202 T 29-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05935 79bd08e7402d9135a727dc313e57e516 499 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 262 279 - T 29-03-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS05935 79bd08e7402d9135a727dc313e57e516 499 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 24 234 1.1E-30 T 29-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CXR48_RS05935 79bd08e7402d9135a727dc313e57e516 499 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 250 442 2.4E-35 T 29-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CXR48_RS05935 79bd08e7402d9135a727dc313e57e516 499 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 499 254.539 T 29-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS10260 a97f51cf83e5327b6f0a46de646c9acd 1495 Gene3D G3DSA:1.10.530.10 1235 1362 1.7E-18 T 29-03-2018 CXR48_RS10260 a97f51cf83e5327b6f0a46de646c9acd 1495 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 168 505 2.1E-82 T 29-03-2018 IPR010090 Phage tail tape measure protein CXR48_RS10260 a97f51cf83e5327b6f0a46de646c9acd 1495 SUPERFAMILY SSF53955 1235 1338 3.97E-14 T 29-03-2018 IPR023346 Lysozyme-like domain CXR48_RS10260 a97f51cf83e5327b6f0a46de646c9acd 1495 Gene3D G3DSA:1.20.120.20 953 1234 2.6E-6 T 29-03-2018 CXR48_RS10260 a97f51cf83e5327b6f0a46de646c9acd 1495 Pfam PF10145 Phage-related minor tail protein 207 405 7.6E-50 T 29-03-2018 IPR010090 Phage tail tape measure protein CXR48_RS10260 a97f51cf83e5327b6f0a46de646c9acd 1495 Gene3D G3DSA:1.20.5.1230 420 857 6.3E-9 T 29-03-2018 CXR48_RS10260 a97f51cf83e5327b6f0a46de646c9acd 1495 Pfam PF01464 Transglycosylase SLT domain 1253 1349 6.1E-15 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 Gene3D G3DSA:3.40.50.970 397 606 4.0E-38 T 29-03-2018 CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 6 634 3.9E-266 T 29-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 440 592 2.7E-41 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 Gene3D G3DSA:3.40.50.970 2 211 2.8E-42 T 29-03-2018 CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 SUPERFAMILY SSF52518 3 210 1.83E-29 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 Hamap MF_01669 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase [iolD]. 2 637 59.923 T 29-03-2018 IPR023757 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, Firmicutes GO:0000287|GO:0016787|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 476 495 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 SUPERFAMILY SSF52467 212 382 7.36E-38 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 197 8.5E-30 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 221 354 5.1E-32 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 Gene3D G3DSA:3.40.50.1220 212 386 3.6E-34 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS18715 f2dfb3d4edd6d528db01ec250c1dcb20 637 SUPERFAMILY SSF52518 417 631 9.4E-55 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS11375 813179f5c18418b55fce83bc224dedad 90 Gene3D G3DSA:1.10.1200.10 1 90 9.3E-9 T 29-03-2018 CXR48_RS11375 813179f5c18418b55fce83bc224dedad 90 SUPERFAMILY SSF47336 7 85 1.57E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS11375 813179f5c18418b55fce83bc224dedad 90 ProSitePatterns PS00012 Phosphopantetheine attachment site. 38 53 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS10950 02f4ec823970be258e7055291a3186b1 194 Gene3D G3DSA:1.10.10.10 75 168 3.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10950 02f4ec823970be258e7055291a3186b1 194 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 30 61 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS10950 02f4ec823970be258e7055291a3186b1 194 Gene3D G3DSA:1.10.1740.10 1 74 2.5E-21 T 29-03-2018 CXR48_RS10950 02f4ec823970be258e7055291a3186b1 194 SUPERFAMILY SSF88946 3 90 1.57E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS10950 02f4ec823970be258e7055291a3186b1 194 SUPERFAMILY SSF88659 92 166 4.11E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS10950 02f4ec823970be258e7055291a3186b1 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 165 2.7E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS10950 02f4ec823970be258e7055291a3186b1 194 Pfam PF04542 Sigma-70 region 2 8 74 6.5E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS10950 02f4ec823970be258e7055291a3186b1 194 Pfam PF08281 Sigma-70, region 4 110 160 3.3E-10 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS16995 bf85481da83041e9cbb9cfd298f982da 444 Pfam PF02040 Arsenical pump membrane protein 3 439 2.1E-64 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS16995 bf85481da83041e9cbb9cfd298f982da 444 PRINTS PR00758 Arsenical pump membrane protein signature 411 435 1.4E-26 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS16995 bf85481da83041e9cbb9cfd298f982da 444 PRINTS PR00758 Arsenical pump membrane protein signature 142 166 1.4E-26 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS16995 bf85481da83041e9cbb9cfd298f982da 444 PRINTS PR00758 Arsenical pump membrane protein signature 378 403 1.4E-26 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS16995 bf85481da83041e9cbb9cfd298f982da 444 PRINTS PR00758 Arsenical pump membrane protein signature 99 123 1.4E-26 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS16995 bf85481da83041e9cbb9cfd298f982da 444 PRINTS PR00758 Arsenical pump membrane protein signature 175 198 1.4E-26 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CXR48_RS14265 27c815f9dc205a36446c846417d5378d 239 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 5 163 1.6E-56 T 29-03-2018 IPR014240 Regulatory protein, YteA family CXR48_RS14265 27c815f9dc205a36446c846417d5378d 239 SUPERFAMILY SSF109635 2 90 2.22E-16 T 29-03-2018 CXR48_RS14265 27c815f9dc205a36446c846417d5378d 239 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 89 113 2.1E-6 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CXR48_RS05490 05049df6c38ed1e260c707bb9899afae 405 Pfam PF01960 ArgJ family 23 405 5.6E-146 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CXR48_RS05490 05049df6c38ed1e260c707bb9899afae 405 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 11 405 1.5E-172 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CXR48_RS05490 05049df6c38ed1e260c707bb9899afae 405 Gene3D G3DSA:3.60.70.12 10 278 2.0E-100 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CXR48_RS05490 05049df6c38ed1e260c707bb9899afae 405 SUPERFAMILY SSF56266 18 401 1.44E-133 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CXR48_RS05490 05049df6c38ed1e260c707bb9899afae 405 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 34 405 4.0E-180 T 29-03-2018 CXR48_RS05490 05049df6c38ed1e260c707bb9899afae 405 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 405 141.428 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 Pfam PF14791 DNA polymerase beta thumb 253 314 3.0E-17 T 29-03-2018 IPR029398 DNA polymerase beta, thumb domain CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:1.10.150.110 1 82 5.7E-16 T 29-03-2018 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 SUPERFAMILY SSF89550 334 569 5.76E-53 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:3.20.20.140 337 560 2.5E-45 T 29-03-2018 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:1.10.150.20 86 145 1.2E-11 T 29-03-2018 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 Pfam PF14520 Helix-hairpin-helix domain 90 144 3.7E-7 T 29-03-2018 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00481 336 415 6.6E-21 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 SUPERFAMILY SSF81301 152 314 6.48E-43 T 29-03-2018 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 Pfam PF02811 PHP domain 337 513 2.6E-7 T 29-03-2018 IPR004013 PHP domain GO:0003824 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00278 88 107 71.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00278 123 142 40.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00278 48 67 110.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 SUPERFAMILY SSF47802 1 81 5.89E-18 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 PIRSF PIRSF005047 1 570 1.2E-238 T 29-03-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:3.30.210.10 246 314 1.6E-18 T 29-03-2018 IPR029398 DNA polymerase beta, thumb domain CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:3.30.460.10 152 244 1.5E-26 T 29-03-2018 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00483 1 314 2.2E-104 T 29-03-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 CXR48_RS13205 8bff67bd96922d4f3ffc39f59ee7e162 570 Pfam PF14716 Helix-hairpin-helix domain 4 69 2.2E-16 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CXR48_RS16160 4975786317b5abb3d3a5bc46195ee2fc 344 SUPERFAMILY SSF53448 4 228 2.11E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16160 4975786317b5abb3d3a5bc46195ee2fc 344 Pfam PF00535 Glycosyl transferase family 2 7 131 4.8E-33 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS16160 4975786317b5abb3d3a5bc46195ee2fc 344 Gene3D G3DSA:3.90.550.10 1 267 4.9E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS11125 f19befdc26bd8b9555a25a6b742ca756 146 SUPERFAMILY SSF55874 28 135 1.7E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS11125 f19befdc26bd8b9555a25a6b742ca756 146 SMART SM00387 35 140 1.1E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS11125 f19befdc26bd8b9555a25a6b742ca756 146 Pfam PF13581 Histidine kinase-like ATPase domain 10 136 1.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS11125 f19befdc26bd8b9555a25a6b742ca756 146 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 35.969 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CXR48_RS11125 f19befdc26bd8b9555a25a6b742ca756 146 Gene3D G3DSA:3.30.565.10 1 145 2.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS11125 f19befdc26bd8b9555a25a6b742ca756 146 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 137 6.0E-79 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CXR48_RS17255 1f6ffdff2affbfa6c5772e6496cbfbca 116 Gene3D G3DSA:3.30.70.120 1 113 1.5E-36 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CXR48_RS17255 1f6ffdff2affbfa6c5772e6496cbfbca 116 Pfam PF00543 Nitrogen regulatory protein P-II 8 109 6.9E-32 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CXR48_RS17255 1f6ffdff2affbfa6c5772e6496cbfbca 116 SMART SM00938 8 109 4.8E-38 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CXR48_RS17255 1f6ffdff2affbfa6c5772e6496cbfbca 116 ProSitePatterns PS00638 P-II protein C-terminal region signature. 87 100 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CXR48_RS17255 1f6ffdff2affbfa6c5772e6496cbfbca 116 PRINTS PR00340 P-II protein signature 6 21 2.2E-21 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CXR48_RS17255 1f6ffdff2affbfa6c5772e6496cbfbca 116 PRINTS PR00340 P-II protein signature 87 107 2.2E-21 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CXR48_RS17255 1f6ffdff2affbfa6c5772e6496cbfbca 116 PRINTS PR00340 P-II protein signature 27 45 2.2E-21 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CXR48_RS17255 1f6ffdff2affbfa6c5772e6496cbfbca 116 PRINTS PR00340 P-II protein signature 56 79 2.2E-21 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CXR48_RS17255 1f6ffdff2affbfa6c5772e6496cbfbca 116 SUPERFAMILY SSF54913 5 116 3.81E-33 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CXR48_RS10765 652dae3923cfb4040d5e821e8c2d1979 362 Gene3D G3DSA:3.40.50.1970 1 172 3.3E-45 T 29-03-2018 CXR48_RS10765 652dae3923cfb4040d5e821e8c2d1979 362 Pfam PF01761 3-dehydroquinate synthase 68 323 3.7E-94 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CXR48_RS10765 652dae3923cfb4040d5e821e8c2d1979 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 355 37.181 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CXR48_RS10765 652dae3923cfb4040d5e821e8c2d1979 362 SUPERFAMILY SSF56796 7 356 3.01E-93 T 29-03-2018 CXR48_RS10765 652dae3923cfb4040d5e821e8c2d1979 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 348 2.9E-115 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CXR48_RS10765 652dae3923cfb4040d5e821e8c2d1979 362 PIRSF PIRSF001455 3 362 1.0E-98 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CXR48_RS10765 652dae3923cfb4040d5e821e8c2d1979 362 Gene3D G3DSA:1.20.1090.10 173 359 4.1E-52 T 29-03-2018 CXR48_RS10080 97eaf51ef9bc42cdf85ddcc128dcd999 301 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 299 9.1E-132 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CXR48_RS10080 97eaf51ef9bc42cdf85ddcc128dcd999 301 Pfam PF04204 Homoserine O-succinyltransferase 2 298 1.7E-137 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CXR48_RS10080 97eaf51ef9bc42cdf85ddcc128dcd999 301 SUPERFAMILY SSF52317 17 296 1.08E-96 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS10080 97eaf51ef9bc42cdf85ddcc128dcd999 301 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 300 54.149 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CXR48_RS10080 97eaf51ef9bc42cdf85ddcc128dcd999 301 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 37 288 2.0E-132 T 29-03-2018 CXR48_RS10080 97eaf51ef9bc42cdf85ddcc128dcd999 301 Gene3D G3DSA:3.40.50.880 34 300 2.8E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS10080 97eaf51ef9bc42cdf85ddcc128dcd999 301 PIRSF PIRSF000450 1 301 3.5E-147 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CXR48_RS07755 c82229fce9db12520e62e6ea2083cdf0 233 Gene3D G3DSA:3.40.50.620 14 233 1.1E-43 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS07755 c82229fce9db12520e62e6ea2083cdf0 233 SUPERFAMILY SSF52402 20 197 1.8E-52 T 29-03-2018 CXR48_RS07755 c82229fce9db12520e62e6ea2083cdf0 233 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 43 231 3.7E-81 T 29-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CXR48_RS07755 c82229fce9db12520e62e6ea2083cdf0 233 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 38 209 9.9E-55 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CXR48_RS07755 c82229fce9db12520e62e6ea2083cdf0 233 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 233 42.566 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CXR48_RS07755 c82229fce9db12520e62e6ea2083cdf0 233 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 24 233 2.6E-101 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CXR48_RS07755 c82229fce9db12520e62e6ea2083cdf0 233 PIRSF PIRSF000857 6 233 6.8E-88 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CXR48_RS18855 2d1288117a76a00eb43e52d930bea41c 206 Pfam PF12804 MobA-like NTP transferase domain 5 171 7.4E-29 T 29-03-2018 IPR025877 MobA-like NTP transferase CXR48_RS18855 2d1288117a76a00eb43e52d930bea41c 206 Gene3D G3DSA:3.90.550.10 1 206 8.7E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS18855 2d1288117a76a00eb43e52d930bea41c 206 SUPERFAMILY SSF53448 1 197 6.76E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS00910 30afbe50c755177a4e04fe3922885c44 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 5.4E-47 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00910 30afbe50c755177a4e04fe3922885c44 130 SUPERFAMILY SSF54211 5 130 1.48E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS00910 30afbe50c755177a4e04fe3922885c44 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CXR48_RS00910 30afbe50c755177a4e04fe3922885c44 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 35.361 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CXR48_RS00910 30afbe50c755177a4e04fe3922885c44 130 Gene3D G3DSA:3.30.230.10 3 130 2.4E-52 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS09730 c2f2f51df370813ec5de141df8bb00be 232 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 1.7E-114 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CXR48_RS09730 c2f2f51df370813ec5de141df8bb00be 232 Gene3D G3DSA:3.40.50.1580 8 232 1.1E-54 T 29-03-2018 CXR48_RS09730 c2f2f51df370813ec5de141df8bb00be 232 Pfam PF01048 Phosphorylase superfamily 15 218 7.6E-42 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CXR48_RS09730 c2f2f51df370813ec5de141df8bb00be 232 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 232 45.496 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CXR48_RS09730 c2f2f51df370813ec5de141df8bb00be 232 SUPERFAMILY SSF53167 2 231 1.83E-90 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CXR48_RS09730 c2f2f51df370813ec5de141df8bb00be 232 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 29-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS11615 4ecff94569ee90607dab3672904b74f1 71 Pfam PF10676 Spore germination protein gerPA/gerPF 6 69 9.3E-16 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 SUPERFAMILY SSF47090 80 137 7.69E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 Pfam PF01471 Putative peptidoglycan binding domain 83 133 1.4E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 Pfam PF01471 Putative peptidoglycan binding domain 222 275 1.2E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 Gene3D G3DSA:3.20.20.80 286 498 1.1E-29 T 29-03-2018 CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 SUPERFAMILY SSF51445 288 479 1.94E-43 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 Gene3D G3DSA:1.10.101.10 71 138 1.6E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 Gene3D G3DSA:1.10.101.10 144 204 0.062 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 SUPERFAMILY SSF47090 208 276 6.91E-13 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 Gene3D G3DSA:1.10.101.10 205 285 3.1E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS01285 d0e1515922b3a22a2ffceb45aa783f8a 734 Pfam PF08924 Domain of unknown function (DUF1906) 299 432 1.5E-37 T 29-03-2018 IPR015020 Protein of unknown function DUF1906 CXR48_RS05585 aa5fcf77293efaf2923f9affd807abb1 542 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 92 114 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CXR48_RS05585 aa5fcf77293efaf2923f9affd807abb1 542 SUPERFAMILY SSF53850 40 540 7.06E-151 T 29-03-2018 CXR48_RS05585 aa5fcf77293efaf2923f9affd807abb1 542 Gene3D G3DSA:3.90.76.10 69 163 1.5E-26 T 29-03-2018 CXR48_RS05585 aa5fcf77293efaf2923f9affd807abb1 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 457 5.0E-100 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CXR48_RS05585 aa5fcf77293efaf2923f9affd807abb1 542 Gene3D G3DSA:3.40.190.10 164 301 8.6E-44 T 29-03-2018 CXR48_RS05585 aa5fcf77293efaf2923f9affd807abb1 542 PIRSF PIRSF002741 3 542 1.3E-165 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CXR48_RS05585 aa5fcf77293efaf2923f9affd807abb1 542 Gene3D G3DSA:3.10.105.10 302 509 5.2E-63 T 29-03-2018 CXR48_RS00605 af1556d6befc553245bdc2a1a7e421aa 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 1.5E-73 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CXR48_RS00605 af1556d6befc553245bdc2a1a7e421aa 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 37.423 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CXR48_RS00605 af1556d6befc553245bdc2a1a7e421aa 158 Gene3D G3DSA:3.30.1330.50 1 158 4.4E-75 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CXR48_RS00605 af1556d6befc553245bdc2a1a7e421aa 158 SUPERFAMILY SSF69765 1 157 6.28E-68 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CXR48_RS00605 af1556d6befc553245bdc2a1a7e421aa 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CXR48_RS00605 af1556d6befc553245bdc2a1a7e421aa 158 Pfam PF02542 YgbB family 2 156 8.8E-67 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CXR48_RS16965 1695b6e27d942c251573031bd8e1d204 305 Gene3D G3DSA:3.40.50.2300 32 151 7.4E-32 T 29-03-2018 CXR48_RS16965 1695b6e27d942c251573031bd8e1d204 305 SUPERFAMILY SSF53822 25 304 1.8E-88 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS16965 1695b6e27d942c251573031bd8e1d204 305 Gene3D G3DSA:3.40.50.2300 152 302 2.1E-43 T 29-03-2018 CXR48_RS16965 1695b6e27d942c251573031bd8e1d204 305 Pfam PF13407 Periplasmic binding protein domain 40 290 4.9E-66 T 29-03-2018 IPR025997 Periplasmic binding protein CXR48_RS01655 336a4b703e3eea17d6464093e33fb11e 272 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 272 2.0E-86 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CXR48_RS01655 336a4b703e3eea17d6464093e33fb11e 272 Pfam PF02540 NAD synthase 23 263 7.8E-79 T 29-03-2018 IPR022310 NAD/GMP synthase CXR48_RS01655 336a4b703e3eea17d6464093e33fb11e 272 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 266 33.015 T 29-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CXR48_RS01655 336a4b703e3eea17d6464093e33fb11e 272 Gene3D G3DSA:3.40.50.620 2 272 1.1E-68 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS01655 336a4b703e3eea17d6464093e33fb11e 272 SUPERFAMILY SSF52402 4 271 3.45E-82 T 29-03-2018 CXR48_RS04480 09f0414bd8f5ed5eed22b869ec829c82 392 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 7 385 31.31 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CXR48_RS04480 09f0414bd8f5ed5eed22b869ec829c82 392 Pfam PF04285 Protein of unknown function (DUF444) 195 383 3.7E-67 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CXR48_RS04480 09f0414bd8f5ed5eed22b869ec829c82 392 Pfam PF04285 Protein of unknown function (DUF444) 11 187 4.1E-35 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CXR48_RS04480 09f0414bd8f5ed5eed22b869ec829c82 392 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 9 380 4.2E-188 T 29-03-2018 IPR014230 Sporulation protein YhbH CXR48_RS01685 3eb3139c0da2a0f1b3e50604b94d127b 318 Gene3D G3DSA:3.40.50.1820 1 318 1.7E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS01685 3eb3139c0da2a0f1b3e50604b94d127b 318 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 313 2.2E-134 T 29-03-2018 IPR008391 Acetyl xylan esterase CXR48_RS01685 3eb3139c0da2a0f1b3e50604b94d127b 318 SUPERFAMILY SSF53474 8 317 4.34E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS08985 1924ab063aea274133fdb558dc6b3fb5 135 SUPERFAMILY SSF51735 6 131 1.61E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08985 1924ab063aea274133fdb558dc6b3fb5 135 Gene3D G3DSA:3.40.50.720 13 134 1.2E-28 T 29-03-2018 CXR48_RS08985 1924ab063aea274133fdb558dc6b3fb5 135 Pfam PF13380 CoA binding domain 17 130 1.1E-33 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CXR48_RS08985 1924ab063aea274133fdb558dc6b3fb5 135 SMART SM00881 12 105 8.3E-16 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CXR48_RS04765 f2b80a4dcd713c1e9f809be66e9f9fad 462 SUPERFAMILY SSF56176 355 429 1.99E-13 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS04765 f2b80a4dcd713c1e9f809be66e9f9fad 462 Gene3D G3DSA:3.10.580.10 196 350 1.3E-26 T 29-03-2018 CXR48_RS04765 f2b80a4dcd713c1e9f809be66e9f9fad 462 Gene3D G3DSA:3.30.465.10 351 433 8.1E-18 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS04765 f2b80a4dcd713c1e9f809be66e9f9fad 462 SMART SM01091 357 433 1.1E-20 T 29-03-2018 IPR005170 Transporter-associated domain CXR48_RS04765 f2b80a4dcd713c1e9f809be66e9f9fad 462 Pfam PF00571 CBS domain 292 341 8.3E-4 T 29-03-2018 IPR000644 CBS domain CXR48_RS04765 f2b80a4dcd713c1e9f809be66e9f9fad 462 Pfam PF00571 CBS domain 219 272 2.6E-4 T 29-03-2018 IPR000644 CBS domain CXR48_RS04765 f2b80a4dcd713c1e9f809be66e9f9fad 462 Pfam PF01595 Domain of unknown function DUF21 9 202 5.2E-49 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CXR48_RS04765 f2b80a4dcd713c1e9f809be66e9f9fad 462 SUPERFAMILY SSF54631 212 355 1.17E-27 T 29-03-2018 CXR48_RS04765 f2b80a4dcd713c1e9f809be66e9f9fad 462 Pfam PF03471 Transporter associated domain 358 431 4.8E-15 T 29-03-2018 IPR005170 Transporter-associated domain CXR48_RS12835 9bb492651eb342eec3342b250dca30c3 383 Gene3D G3DSA:3.40.640.10 10 248 2.1E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS12835 9bb492651eb342eec3342b250dca30c3 383 Pfam PF00266 Aminotransferase class-V 2 366 2.2E-79 T 29-03-2018 IPR000192 Aminotransferase class V domain CXR48_RS12835 9bb492651eb342eec3342b250dca30c3 383 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 191 210 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CXR48_RS12835 9bb492651eb342eec3342b250dca30c3 383 SUPERFAMILY SSF53383 1 374 1.17E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS12835 9bb492651eb342eec3342b250dca30c3 383 Gene3D G3DSA:3.90.1150.10 249 366 2.1E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS12835 9bb492651eb342eec3342b250dca30c3 383 PIRSF PIRSF005572 1 381 1.1E-117 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 SMART SM00345 7 66 5.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 Gene3D G3DSA:3.40.1410.10 77 237 1.9E-37 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 6.7E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 2.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 2.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 SUPERFAMILY SSF46785 1 70 6.71E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 SMART SM00866 90 229 2.9E-41 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 SUPERFAMILY SSF64288 82 231 1.86E-45 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 Gene3D G3DSA:1.10.10.10 1 67 6.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02930 3680fa2be1fee87a07fdccb47d1288a0 238 Pfam PF07702 UTRA domain 92 228 1.2E-36 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS11250 1c9c0c9fe3db2c1f1b8e422f16176707 114 SUPERFAMILY SSF54909 5 102 2.82E-30 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS11250 1c9c0c9fe3db2c1f1b8e422f16176707 114 Gene3D G3DSA:3.30.70.100 10 102 3.4E-23 T 29-03-2018 CXR48_RS11250 1c9c0c9fe3db2c1f1b8e422f16176707 114 Pfam PF03992 Antibiotic biosynthesis monooxygenase 13 84 2.2E-7 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CXR48_RS00905 8584f97ce27c3035c39c865d54f1cdc3 145 PIRSF PIRSF002181 1 143 1.0E-50 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00905 8584f97ce27c3035c39c865d54f1cdc3 145 Pfam PF00572 Ribosomal protein L13 15 139 9.2E-58 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00905 8584f97ce27c3035c39c865d54f1cdc3 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 28.654 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00905 8584f97ce27c3035c39c865d54f1cdc3 145 Gene3D G3DSA:3.90.1180.10 1 145 3.8E-61 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00905 8584f97ce27c3035c39c865d54f1cdc3 145 SUPERFAMILY SSF52161 6 143 5.49E-60 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00905 8584f97ce27c3035c39c865d54f1cdc3 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 6 142 4.1E-66 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00905 8584f97ce27c3035c39c865d54f1cdc3 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CXR48_RS14890 731118cbe8e8f28258d20024b269c8e9 541 Pfam PF00501 AMP-binding enzyme 32 435 9.9E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS14890 731118cbe8e8f28258d20024b269c8e9 541 SUPERFAMILY SSF56801 8 531 1.44E-140 T 29-03-2018 CXR48_RS14890 731118cbe8e8f28258d20024b269c8e9 541 Gene3D G3DSA:3.40.50.980 22 174 5.8E-35 T 29-03-2018 CXR48_RS14890 731118cbe8e8f28258d20024b269c8e9 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS14890 731118cbe8e8f28258d20024b269c8e9 541 Gene3D G3DSA:3.30.300.30 430 535 3.3E-25 T 29-03-2018 CXR48_RS14890 731118cbe8e8f28258d20024b269c8e9 541 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 4 526 1.1E-260 T 29-03-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 CXR48_RS14890 731118cbe8e8f28258d20024b269c8e9 541 Gene3D G3DSA:2.30.38.10 354 429 2.3E-21 T 29-03-2018 CXR48_RS14890 731118cbe8e8f28258d20024b269c8e9 541 Gene3D G3DSA:3.40.50.980 175 340 1.7E-32 T 29-03-2018 CXR48_RS14890 731118cbe8e8f28258d20024b269c8e9 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 519 1.9E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS13580 7128ca379c3ec8ebe27d12ff0930d1e5 170 SUPERFAMILY SSF53218 8 167 1.23E-41 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS13580 7128ca379c3ec8ebe27d12ff0930d1e5 170 PIRSF PIRSF006443 1 170 2.9E-67 T 29-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 CXR48_RS13580 7128ca379c3ec8ebe27d12ff0930d1e5 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 157 3.9E-37 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS13580 7128ca379c3ec8ebe27d12ff0930d1e5 170 SMART SM00852 17 162 7.3E-26 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS13580 7128ca379c3ec8ebe27d12ff0930d1e5 170 Gene3D G3DSA:3.40.980.10 1 168 2.2E-31 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS13580 7128ca379c3ec8ebe27d12ff0930d1e5 170 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CXR48_RS13580 7128ca379c3ec8ebe27d12ff0930d1e5 170 Pfam PF00994 Probable molybdopterin binding domain 18 161 2.5E-35 T 29-03-2018 IPR001453 MoaB/Mog domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Pfam PF00501 AMP-binding enzyme 1510 1905 2.8E-103 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Pfam PF00501 AMP-binding enzyme 475 867 4.0E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF47336 2010 2075 1.09E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:1.10.1200.10 980 1043 2.8E-21 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:3.40.50.980 616 771 2.3E-38 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 614 625 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF52777 13 192 5.89E-46 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:2.30.38.10 778 857 6.5E-20 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Pfam PF13193 AMP-binding enzyme C-terminal domain 1913 1988 3.1E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 948 1.6E-5 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:3.40.50.980 1501 1652 3.7E-48 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF52777 1231 1474 4.45E-55 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2038 2053 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1531 1929 4.5E-136 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 496 891 1.2E-125 T 29-03-2018 IPR010071 Amino acid adenylation domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:3.40.50.980 1653 1806 4.6E-40 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF56801 1470 2027 4.06E-157 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:2.30.38.10 1807 1897 1.1E-20 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1647 1658 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:3.30.300.30 862 979 3.5E-36 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:3.30.300.30 1900 2019 9.2E-36 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:1.10.1200.10 2020 2080 1.8E-17 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF52777 2283 2539 2.0E-37 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Pfam PF00668 Condensation domain 1057 1491 8.0E-130 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Pfam PF00668 Condensation domain 2092 2551 8.3E-110 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Pfam PF00668 Condensation domain 8 455 1.2E-131 T 29-03-2018 IPR001242 Condensation domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Pfam PF00550 Phosphopantetheine attachment site 2019 2075 5.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Pfam PF00550 Phosphopantetheine attachment site 976 1039 2.8E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:3.40.50.980 468 615 7.3E-42 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF56801 453 986 1.1E-145 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF52777 2088 2269 2.0E-37 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF52777 195 440 2.33E-50 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:3.30.559.10 1044 1247 1.4E-45 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:3.30.559.10 2081 2298 3.3E-32 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 Gene3D G3DSA:3.30.559.10 1 216 2.1E-36 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2408 2558 3.2E-44 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF52777 1061 1225 2.45E-46 T 29-03-2018 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SUPERFAMILY SSF47336 966 1040 2.36E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SMART SM00823 Phosphopantetheine attachment site 974 1043 0.0014 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS09245 1de7ee4db0606a84c28d168879818666 2565 SMART SM00823 Phosphopantetheine attachment site 2014 2082 0.012 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Pfam PF03448 MgtE intracellular N domain 33 133 2.0E-20 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Gene3D G3DSA:3.10.580.10 126 261 2.4E-20 T 29-03-2018 CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SMART SM00116 143 196 3.3 T 29-03-2018 IPR000644 CBS domain CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SMART SM00116 207 255 0.0011 T 29-03-2018 IPR000644 CBS domain CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SMART SM00924 33 136 4.8E-26 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Pfam PF00571 CBS domain 137 192 7.4E-6 T 29-03-2018 IPR000644 CBS domain CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Pfam PF00571 CBS domain 200 254 2.1E-6 T 29-03-2018 IPR000644 CBS domain CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 TIGRFAM TIGR00400 mgtE: magnesium transporter 4 450 9.4E-208 T 29-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Gene3D G3DSA:1.25.60.10 1 125 8.9E-17 T 29-03-2018 CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SUPERFAMILY SSF161093 281 448 2.62E-53 T 29-03-2018 CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Pfam PF01769 Divalent cation transporter 320 441 4.6E-31 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SUPERFAMILY SSF54631 136 266 4.17E-29 T 29-03-2018 CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SUPERFAMILY SSF158791 8 132 2.35E-26 T 29-03-2018 CXR48_RS06605 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Gene3D G3DSA:1.10.357.20 278 451 8.9E-44 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CXR48_RS18785 6944437af1188568a93ff4e06f29e096 445 PIRSF PIRSF036492 1 445 1.1E-163 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CXR48_RS18785 6944437af1188568a93ff4e06f29e096 445 Gene3D G3DSA:3.40.309.10 233 419 5.2E-61 T 29-03-2018 CXR48_RS18785 6944437af1188568a93ff4e06f29e096 445 SUPERFAMILY SSF53720 7 442 4.32E-118 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS18785 6944437af1188568a93ff4e06f29e096 445 Gene3D G3DSA:3.40.605.10 2 232 1.5E-63 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS18785 6944437af1188568a93ff4e06f29e096 445 Pfam PF00171 Aldehyde dehydrogenase family 6 437 9.0E-95 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS18785 6944437af1188568a93ff4e06f29e096 445 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 213 220 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS18785 6944437af1188568a93ff4e06f29e096 445 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 241 252 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS10095 5e14d65bae19d9d813d1c3f6438f1667 60 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 60 7.0E-17 T 29-03-2018 CXR48_RS01885 b08b50f960afe54b605a462cc7f93916 372 Pfam PF03845 Spore germination protein 5 325 2.5E-88 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CXR48_RS01885 b08b50f960afe54b605a462cc7f93916 372 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 363 2.7E-77 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 Pfam PF00149 Calcineurin-like phosphoesterase 57 295 1.8E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 649 679 0.0017 T 29-03-2018 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 Gene3D G3DSA:3.60.21.10 46 368 1.6E-70 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 SUPERFAMILY SSF55816 368 561 2.49E-40 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 Pfam PF02872 5'-nucleotidase, C-terminal domain 370 507 2.6E-29 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 SUPERFAMILY SSF56300 52 367 8.59E-69 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 PRINTS PR01607 Apyrase family signature 489 508 1.9E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 PRINTS PR01607 Apyrase family signature 421 444 1.9E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 PRINTS PR01607 Apyrase family signature 304 324 1.9E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 PRINTS PR01607 Apyrase family signature 250 267 1.9E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 PRINTS PR01607 Apyrase family signature 55 73 1.9E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 PRINTS PR01607 Apyrase family signature 278 301 1.9E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 ProSitePatterns PS00786 5'-nucleotidase signature 2. 140 151 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS04580 ba55228f1cad8a58ec534b7f8d7b3b73 684 Gene3D G3DSA:3.90.780.10 369 554 3.5E-38 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 SMART SM00387 419 527 1.7E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 526 1.6E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 Gene3D G3DSA:1.10.287.130 316 374 5.6E-18 T 29-03-2018 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 SUPERFAMILY SSF55874 393 526 4.06E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 Pfam PF00989 PAS fold 212 312 4.7E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 Gene3D G3DSA:3.30.450.20 30 169 8.9E-24 T 29-03-2018 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 Gene3D G3DSA:3.30.450.20 215 315 6.1E-10 T 29-03-2018 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 486 1.4E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 1.4E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 1.4E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 1.4E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 Pfam PF17203 Single cache domain 3 36 170 8.0E-26 T 29-03-2018 IPR033463 Single cache domain 3 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 322 377 2.3E-13 T 29-03-2018 CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 Gene3D G3DSA:3.30.565.10 375 528 1.7E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 SMART SM00091 212 280 0.001 T 29-03-2018 IPR000014 PAS domain CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 SUPERFAMILY SSF103190 36 169 5.49E-37 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS14675 1ec8ce272ca6540d307a2864d6d58f51 533 SUPERFAMILY SSF55890 323 407 1.44E-16 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CXR48_RS01735 5a9226c0905daa2d6a0cb744ee6a53ad 400 SUPERFAMILY SSF52540 2 308 1.01E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01735 5a9226c0905daa2d6a0cb744ee6a53ad 400 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 210 7.0E-59 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CXR48_RS01735 5a9226c0905daa2d6a0cb744ee6a53ad 400 SMART SM00833 259 375 1.0E-50 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CXR48_RS01735 5a9226c0905daa2d6a0cb744ee6a53ad 400 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 259 375 4.2E-26 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CXR48_RS01735 5a9226c0905daa2d6a0cb744ee6a53ad 400 Gene3D G3DSA:3.40.50.300 1 229 1.5E-51 T 29-03-2018 CXR48_RS01735 5a9226c0905daa2d6a0cb744ee6a53ad 400 Gene3D G3DSA:3.30.1220.10 241 376 3.6E-32 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 7.8E-45 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 Pfam PF00108 Thiolase, N-terminal domain 5 263 3.3E-98 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 Gene3D G3DSA:3.40.47.10 264 390 5.8E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 PIRSF PIRSF000429 2 393 2.2E-116 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 SUPERFAMILY SSF53901 271 392 1.15E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 SUPERFAMILY SSF53901 4 268 4.01E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 Gene3D G3DSA:3.40.47.10 2 263 4.3E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 1.5E-139 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CXR48_RS11580 0a68dc570214ece7b55503d51265906d 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 124 1036 5.0E-252 T 29-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 SUPERFAMILY SSF158745 674 1047 7.59E-62 T 29-03-2018 CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 Pfam PF05147 Lanthionine synthetase C-like protein 694 1042 1.4E-58 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 Pfam PF13575 Domain of unknown function (DUF4135) 195 565 3.6E-100 T 29-03-2018 IPR025410 Lantibiotic biosynthesis protein, dehydration domain CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 Gene3D G3DSA:1.50.10.10 635 788 7.2E-11 T 29-03-2018 CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 Gene3D G3DSA:1.50.10.10 789 1042 0.015 T 29-03-2018 CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 PRINTS PR01950 LanC-like protein superfamily signature 798 813 1.2E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 PRINTS PR01950 LanC-like protein superfamily signature 1018 1035 1.2E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 PRINTS PR01950 LanC-like protein superfamily signature 856 872 1.2E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 PRINTS PR01950 LanC-like protein superfamily signature 914 934 1.2E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 PRINTS PR01950 LanC-like protein superfamily signature 963 976 1.2E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 PRINTS PR01950 LanC-like protein superfamily signature 696 714 1.2E-15 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 SMART SM01260 693 1048 1.6E-56 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CXR48_RS06140 6774d2c0a45bca53654ae16b3f8e77d4 1060 PIRSF PIRSF037228 13 1048 2.6E-219 T 29-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM CXR48_RS07805 34ae78d8b9349eaa6beaaccc4824a583 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 291 3.4E-120 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 CXR48_RS07805 34ae78d8b9349eaa6beaaccc4824a583 291 Pfam PF08340 Domain of unknown function (DUF1732) 208 291 6.8E-38 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 CXR48_RS07805 34ae78d8b9349eaa6beaaccc4824a583 291 Pfam PF03755 YicC-like family, N-terminal region 2 156 8.8E-37 T 29-03-2018 IPR013527 YicC-like, N-terminal CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 SUPERFAMILY SSF51735 6 259 5.1E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 Gene3D G3DSA:3.40.50.720 2 264 2.8E-62 T 29-03-2018 CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 Pfam PF00106 short chain dehydrogenase 8 194 1.0E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15810 8bb29ef1ae1284c4b2283729a2faa9e7 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS13210 8703786d9ec5ae6f3f0052b08efde984 177 Pfam PF02674 Colicin V production protein 2 162 1.0E-32 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CXR48_RS15275 c7648067ce9a84d128bb2ff7ab48dcff 437 Pfam PF01458 Uncharacterized protein family (UPF0051) 186 411 3.8E-62 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CXR48_RS15275 c7648067ce9a84d128bb2ff7ab48dcff 437 SUPERFAMILY SSF101960 12 436 2.62E-118 T 29-03-2018 CXR48_RS15275 c7648067ce9a84d128bb2ff7ab48dcff 437 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 152 428 1.4E-74 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 SUPERFAMILY SSF54768 164 245 4.24E-23 T 29-03-2018 CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 23 242 2.6E-81 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 SMART SM00535 35 170 2.1E-62 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 SMART SM00358 176 243 8.4E-23 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 Hamap MF_00104 Ribonuclease 3 [rnc]. 23 239 31.944 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 SUPERFAMILY SSF69065 17 177 5.93E-53 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 Pfam PF14622 Ribonuclease-III-like 33 164 1.3E-37 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 Gene3D G3DSA:1.10.1520.10 19 168 4.6E-45 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 Pfam PF00035 Double-stranded RNA binding motif 177 242 3.2E-16 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 ProSitePatterns PS00517 Ribonuclease III family signature. 59 67 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CXR48_RS07940 da7a21662e0b257e76f9f6ab8a748e1d 249 Gene3D G3DSA:3.30.160.20 174 249 5.2E-22 T 29-03-2018 CXR48_RS13620 41dc1aa6aa5c5a54504fa74e3d0dbfcd 268 Hamap MF_00361 NAD kinase [nadK]. 6 268 21.679 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CXR48_RS13620 41dc1aa6aa5c5a54504fa74e3d0dbfcd 268 SUPERFAMILY SSF111331 10 266 6.05E-54 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CXR48_RS13620 41dc1aa6aa5c5a54504fa74e3d0dbfcd 268 Gene3D G3DSA:2.60.200.30 123 245 3.7E-24 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CXR48_RS13620 41dc1aa6aa5c5a54504fa74e3d0dbfcd 268 Gene3D G3DSA:3.40.50.10330 6 122 2.5E-12 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CXR48_RS13620 41dc1aa6aa5c5a54504fa74e3d0dbfcd 268 Pfam PF01513 ATP-NAD kinase 16 252 2.8E-12 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CXR48_RS00200 1b181bdae4b68f1ae3afc17e3d952bb9 477 Gene3D G3DSA:3.90.100.10 378 477 1.1E-18 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CXR48_RS00200 1b181bdae4b68f1ae3afc17e3d952bb9 477 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 3 306 5.6E-96 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CXR48_RS00200 1b181bdae4b68f1ae3afc17e3d952bb9 477 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 313 360 1.7E-6 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CXR48_RS00200 1b181bdae4b68f1ae3afc17e3d952bb9 477 Gene3D G3DSA:3.40.640.10 3 276 2.6E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS00200 1b181bdae4b68f1ae3afc17e3d952bb9 477 SUPERFAMILY SSF55904 333 467 6.41E-20 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CXR48_RS00200 1b181bdae4b68f1ae3afc17e3d952bb9 477 Gene3D G3DSA:3.90.1150.10 277 377 1.2E-9 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS00200 1b181bdae4b68f1ae3afc17e3d952bb9 477 SUPERFAMILY SSF53383 3 357 3.76E-82 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS00200 1b181bdae4b68f1ae3afc17e3d952bb9 477 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 403 461 1.4E-8 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CXR48_RS12305 2e5d673492eb9bd991ac5f49f0aa2764 273 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 97 1.1E-22 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CXR48_RS12305 2e5d673492eb9bd991ac5f49f0aa2764 273 Gene3D G3DSA:1.10.3730.10 162 263 7.5E-19 T 29-03-2018 CXR48_RS12305 2e5d673492eb9bd991ac5f49f0aa2764 273 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 261 3.9E-17 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CXR48_RS12305 2e5d673492eb9bd991ac5f49f0aa2764 273 SUPERFAMILY SSF51735 2 156 4.01E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS12305 2e5d673492eb9bd991ac5f49f0aa2764 273 Gene3D G3DSA:3.40.50.720 1 161 3.7E-24 T 29-03-2018 CXR48_RS12305 2e5d673492eb9bd991ac5f49f0aa2764 273 SUPERFAMILY SSF48179 162 262 2.38E-18 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS12305 2e5d673492eb9bd991ac5f49f0aa2764 273 PIRSF PIRSF000193 1 265 9.6E-79 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CXR48_RS12305 2e5d673492eb9bd991ac5f49f0aa2764 273 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CXR48_RS15170 6a1a0d01251bc63ddbb5fc2a1e5220a8 417 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 189 209 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CXR48_RS15170 6a1a0d01251bc63ddbb5fc2a1e5220a8 417 Gene3D G3DSA:3.90.1150.10 294 415 5.8E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS15170 6a1a0d01251bc63ddbb5fc2a1e5220a8 417 Gene3D G3DSA:3.40.640.10 20 293 3.2E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS15170 6a1a0d01251bc63ddbb5fc2a1e5220a8 417 SUPERFAMILY SSF53383 10 391 2.61E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS15170 6a1a0d01251bc63ddbb5fc2a1e5220a8 417 Pfam PF00266 Aminotransferase class-V 36 355 8.3E-32 T 29-03-2018 IPR000192 Aminotransferase class V domain CXR48_RS15170 6a1a0d01251bc63ddbb5fc2a1e5220a8 417 PIRSF PIRSF000524 5 412 1.8E-139 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 45.768 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 PRINTS PR01874 DNA repair protein radA signature 322 345 3.4E-94 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 PRINTS PR01874 DNA repair protein radA signature 10 34 3.4E-94 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 PRINTS PR01874 DNA repair protein radA signature 213 241 3.4E-94 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 PRINTS PR01874 DNA repair protein radA signature 82 110 3.4E-94 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 PRINTS PR01874 DNA repair protein radA signature 124 141 3.4E-94 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 PRINTS PR01874 DNA repair protein radA signature 248 274 3.4E-94 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 PRINTS PR01874 DNA repair protein radA signature 174 198 3.4E-94 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 Gene3D G3DSA:3.30.230.10 261 457 2.9E-41 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 Pfam PF13481 AAA domain 71 222 5.4E-17 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 452 8.1E-229 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 SUPERFAMILY SSF54211 303 455 2.73E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 SUPERFAMILY SSF54211 255 269 2.73E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 SMART SM00382 90 244 3.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 Gene3D G3DSA:3.40.50.300 30 260 6.3E-23 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 Pfam PF13541 Subunit ChlI of Mg-chelatase 364 430 4.1E-9 T 29-03-2018 CXR48_RS00585 273e333912f6d1dbfa98b3d84e5b20ea 459 SUPERFAMILY SSF52540 68 292 1.9E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 23.848 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 SMART SM00382 25 564 22.0 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 SMART SM00382 631 906 5.7E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 922 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 SUPERFAMILY SSF52540 438 569 1.65E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 SUPERFAMILY SSF52540 10 206 1.65E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 Gene3D G3DSA:1.20.1580.10 691 828 6.6E-46 T 29-03-2018 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 SUPERFAMILY SSF52540 613 912 2.05E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 Gene3D G3DSA:3.40.50.300 2 36 1.1E-7 T 29-03-2018 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 Gene3D G3DSA:3.30.190.20 141 247 1.1E-44 T 29-03-2018 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 Gene3D G3DSA:3.40.50.300 37 140 1.2E-8 T 29-03-2018 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 Gene3D G3DSA:3.40.50.300 835 946 0.098 T 29-03-2018 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 Pfam PF00005 ABC transporter 622 858 5.0E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 Gene3D G3DSA:1.10.8.280 284 405 5.3E-43 T 29-03-2018 CXR48_RS16540 15d6ece8410aaae7b3911f5340cd82b8 957 Gene3D G3DSA:3.40.50.300 421 678 1.9E-23 T 29-03-2018 CXR48_RS10785 cdb55b758b397550174b163fd3105f38 349 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 31 349 8.9E-174 T 29-03-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 CXR48_RS10785 cdb55b758b397550174b163fd3105f38 349 SUPERFAMILY SSF48576 35 348 8.96E-88 T 29-03-2018 IPR008949 Isoprenoid synthase domain CXR48_RS10785 cdb55b758b397550174b163fd3105f38 349 Pfam PF00348 Polyprenyl synthetase 60 291 2.6E-68 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CXR48_RS10785 cdb55b758b397550174b163fd3105f38 349 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 110 124 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CXR48_RS10785 cdb55b758b397550174b163fd3105f38 349 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 232 244 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CXR48_RS10785 cdb55b758b397550174b163fd3105f38 349 Gene3D G3DSA:1.10.600.10 18 349 6.5E-91 T 29-03-2018 IPR008949 Isoprenoid synthase domain CXR48_RS05270 e0720a8f8dc1c938c3ce989ebe25ac20 237 Gene3D G3DSA:3.30.240.20 83 152 1.0E-22 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CXR48_RS05270 e0720a8f8dc1c938c3ce989ebe25ac20 237 Pfam PF04239 Protein of unknown function (DUF421) 90 206 1.7E-35 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CXR48_RS05270 e0720a8f8dc1c938c3ce989ebe25ac20 237 Gene3D G3DSA:3.30.240.20 173 227 6.8E-15 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CXR48_RS05465 ac8066737acdf97e06728a4008aa3d5f 102 Gene3D G3DSA:3.30.300.130 2 101 8.8E-29 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CXR48_RS05465 ac8066737acdf97e06728a4008aa3d5f 102 Pfam PF01883 Iron-sulfur cluster assembly protein 6 80 4.4E-23 T 29-03-2018 IPR002744 MIP18 family-like CXR48_RS05465 ac8066737acdf97e06728a4008aa3d5f 102 SUPERFAMILY SSF117916 4 100 4.25E-33 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CXR48_RS08200 95b47878c5cbd62c44e1f3dc3c388078 157 Gene3D G3DSA:2.30.30.40 92 137 7.5E-14 T 29-03-2018 CXR48_RS08200 95b47878c5cbd62c44e1f3dc3c388078 157 Pfam PF01584 CheW-like domain 11 144 6.6E-32 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CXR48_RS08200 95b47878c5cbd62c44e1f3dc3c388078 157 Gene3D G3DSA:2.40.50.180 27 91 3.1E-20 T 29-03-2018 CXR48_RS08200 95b47878c5cbd62c44e1f3dc3c388078 157 SMART SM00260 6 143 4.2E-40 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CXR48_RS08200 95b47878c5cbd62c44e1f3dc3c388078 157 SUPERFAMILY SSF50341 10 144 4.97E-34 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CXR48_RS13960 af0b32345e4025049fe56a85359bd25f 341 Gene3D G3DSA:3.40.50.2300 167 338 6.4E-42 T 29-03-2018 CXR48_RS13960 af0b32345e4025049fe56a85359bd25f 341 SUPERFAMILY SSF53822 77 329 8.64E-48 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS13960 af0b32345e4025049fe56a85359bd25f 341 SMART SM00354 1 75 5.5E-15 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS13960 af0b32345e4025049fe56a85359bd25f 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 CXR48_RS13960 af0b32345e4025049fe56a85359bd25f 341 Gene3D G3DSA:1.10.260.40 2 61 2.6E-16 T 29-03-2018 CXR48_RS13960 af0b32345e4025049fe56a85359bd25f 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 50 3.9E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS13960 af0b32345e4025049fe56a85359bd25f 341 Gene3D G3DSA:3.40.50.2300 62 166 3.5E-13 T 29-03-2018 CXR48_RS13960 af0b32345e4025049fe56a85359bd25f 341 Pfam PF13377 Periplasmic binding protein-like domain 169 335 2.9E-32 T 29-03-2018 CXR48_RS13960 af0b32345e4025049fe56a85359bd25f 341 SUPERFAMILY SSF47413 3 53 8.34E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS14480 4dd46ca27b1beccbc031cb52595dbe59 328 SUPERFAMILY SSF55347 129 292 2.29E-28 T 29-03-2018 CXR48_RS14480 4dd46ca27b1beccbc031cb52595dbe59 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 1.0E-23 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CXR48_RS14480 4dd46ca27b1beccbc031cb52595dbe59 328 Gene3D G3DSA:3.30.360.10 144 327 1.9E-33 T 29-03-2018 CXR48_RS14480 4dd46ca27b1beccbc031cb52595dbe59 328 Gene3D G3DSA:3.40.50.720 1 143 4.5E-37 T 29-03-2018 CXR48_RS14480 4dd46ca27b1beccbc031cb52595dbe59 328 SUPERFAMILY SSF51735 2 152 1.91E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11305 aad4787737f2b0eea24bf0e8deb734ff 319 SUPERFAMILY SSF56281 12 309 2.75E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11305 aad4787737f2b0eea24bf0e8deb734ff 319 Pfam PF00753 Metallo-beta-lactamase superfamily 20 231 6.8E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11305 aad4787737f2b0eea24bf0e8deb734ff 319 Gene3D G3DSA:3.60.15.10 1 259 1.3E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11305 aad4787737f2b0eea24bf0e8deb734ff 319 SMART SM00849 19 231 8.4E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 Gene3D G3DSA:3.40.50.720 1 39 7.8E-7 T 29-03-2018 CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 Gene3D G3DSA:3.40.50.720 40 242 2.4E-55 T 29-03-2018 CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 241 5.8E-53 T 29-03-2018 CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 8.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 8.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 8.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS08420 1d16958acc5974707f987d619e30bf53 242 SUPERFAMILY SSF51735 3 241 5.01E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01845 e44dbc029e87640fc635abfbadf3cc39 473 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 441 6.4E-163 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CXR48_RS01845 e44dbc029e87640fc635abfbadf3cc39 473 SUPERFAMILY SSF143968 311 462 3.27E-41 T 29-03-2018 CXR48_RS01845 e44dbc029e87640fc635abfbadf3cc39 473 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 415 2.8E-116 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CXR48_RS01845 e44dbc029e87640fc635abfbadf3cc39 473 Hamap MF_01985 Phenolic acid decarboxylase subunit C. 1 472 74.214 T 29-03-2018 IPR032902 Phenolic acid decarboxylase subunit C GO:0016831 KEGG: 00627+4.1.1.61 CXR48_RS01845 e44dbc029e87640fc635abfbadf3cc39 473 SUPERFAMILY SSF50475 3 308 3.77E-88 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CXR48_RS01845 e44dbc029e87640fc635abfbadf3cc39 473 Gene3D G3DSA:3.40.1670.10 310 453 1.4E-33 T 29-03-2018 CXR48_RS08650 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 Pfam PF17209 Hfq protein 6 68 4.3E-33 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CXR48_RS08650 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 2 64 29.964 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CXR48_RS08650 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 5.8E-32 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CXR48_RS08650 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 SUPERFAMILY SSF50182 5 63 3.89E-24 T 29-03-2018 IPR010920 LSM domain CXR48_RS08650 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 Gene3D G3DSA:2.30.30.100 3 73 1.4E-33 T 29-03-2018 CXR48_RS04215 fab4b0d778e54d468680d9aa850b605a 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 425 3.5E-171 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CXR48_RS04215 fab4b0d778e54d468680d9aa850b605a 429 SUPERFAMILY SSF53383 3 425 4.31E-125 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS04215 fab4b0d778e54d468680d9aa850b605a 429 Gene3D G3DSA:3.90.1150.10 316 429 1.8E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS04215 fab4b0d778e54d468680d9aa850b605a 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 4 427 94.094 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CXR48_RS04215 fab4b0d778e54d468680d9aa850b605a 429 Pfam PF00202 Aminotransferase class-III 35 420 2.9E-71 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS04215 fab4b0d778e54d468680d9aa850b605a 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS04215 fab4b0d778e54d468680d9aa850b605a 429 Gene3D G3DSA:3.90.1150.10 2 167 2.2E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS04215 fab4b0d778e54d468680d9aa850b605a 429 Gene3D G3DSA:3.40.640.10 168 315 1.4E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS12190 99126203c382cf256ede21f93bf739d0 330 Gene3D G3DSA:1.20.1600.10 61 293 9.9E-4 T 29-03-2018 CXR48_RS12190 99126203c382cf256ede21f93bf739d0 330 Pfam PF12127 SigmaW regulon antibacterial 10 319 9.5E-164 T 29-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CXR48_RS12190 99126203c382cf256ede21f93bf739d0 330 Hamap MF_01562 UPF0365 protein . 3 323 49.932 T 29-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CXR48_RS07265 e5615339d63a01b2b49a2c3b1511a629 371 SUPERFAMILY SSF52518 13 367 1.16E-102 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS07265 e5615339d63a01b2b49a2c3b1511a629 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 24 363 1.1E-141 T 29-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CXR48_RS07265 e5615339d63a01b2b49a2c3b1511a629 371 Gene3D G3DSA:3.40.50.970 1 364 3.9E-86 T 29-03-2018 CXR48_RS07265 e5615339d63a01b2b49a2c3b1511a629 371 Pfam PF00676 Dehydrogenase E1 component 53 343 2.7E-103 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CXR48_RS07590 6930fb06808004ad046627a5019453cc 363 SUPERFAMILY SSF53756 1 361 1.98E-108 T 29-03-2018 CXR48_RS07590 6930fb06808004ad046627a5019453cc 363 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 357 3.8E-112 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CXR48_RS07590 6930fb06808004ad046627a5019453cc 363 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 33.717 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CXR48_RS07590 6930fb06808004ad046627a5019453cc 363 Gene3D G3DSA:3.40.50.2000 179 346 2.1E-31 T 29-03-2018 CXR48_RS07590 6930fb06808004ad046627a5019453cc 363 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 353 1.6E-43 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CXR48_RS07590 6930fb06808004ad046627a5019453cc 363 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 143 9.6E-51 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CXR48_RS07590 6930fb06808004ad046627a5019453cc 363 Gene3D G3DSA:3.40.50.2000 1 178 4.6E-38 T 29-03-2018 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 SUPERFAMILY SSF51556 133 433 3.48E-189 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 SUPERFAMILY SSF51556 482 569 3.48E-189 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 Gene3D G3DSA:3.20.20.140 411 434 0.12 T 29-03-2018 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 2 569 7.2E-293 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 Gene3D G3DSA:3.20.20.140 435 555 1.3E-46 T 29-03-2018 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 Gene3D G3DSA:3.20.20.140 144 410 1.8E-153 T 29-03-2018 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 ProSitePatterns PS01120 Urease nickel ligands signature. 130 143 - T 29-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 SUPERFAMILY SSF51338 424 479 1.38E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 Hamap MF_01953 Urease subunit alpha [ureC]. 1 569 57.427 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 SUPERFAMILY SSF51338 2 180 2.55E-66 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 ProSitePatterns PS00145 Urease active site. 320 336 - T 29-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 Gene3D G3DSA:2.30.40.10 66 143 7.8E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 Pfam PF00449 Urease alpha-subunit, N-terminal domain 1 122 3.5E-57 T 29-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 Pfam PF01979 Amidohydrolase family 128 455 1.6E-77 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 429 442 7.2E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 298 315 7.2E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 337 353 7.2E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17320 2089b684cc7f51cfa137f3df0c65671b 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 403 418 7.2E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS13120 e0b7f9f7816408c348bacc654c6d6ec2 252 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 116 6.6E-28 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13120 e0b7f9f7816408c348bacc654c6d6ec2 252 Gene3D G3DSA:1.10.1060.10 112 248 6.5E-19 T 29-03-2018 CXR48_RS13120 e0b7f9f7816408c348bacc654c6d6ec2 252 Pfam PF13183 4Fe-4S dicluster domain 150 225 1.5E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CXR48_RS13120 e0b7f9f7816408c348bacc654c6d6ec2 252 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 154 165 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CXR48_RS13120 e0b7f9f7816408c348bacc654c6d6ec2 252 SUPERFAMILY SSF54292 2 111 5.97E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CXR48_RS13120 e0b7f9f7816408c348bacc654c6d6ec2 252 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 10 233 2.3E-39 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13120 e0b7f9f7816408c348bacc654c6d6ec2 252 Gene3D G3DSA:3.10.20.30 1 110 4.5E-24 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS13120 e0b7f9f7816408c348bacc654c6d6ec2 252 SUPERFAMILY SSF46548 113 237 2.96E-27 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CXR48_RS08605 9fa672c73688ce1e8c993d1e22a5c68c 442 SUPERFAMILY SSF52743 143 439 1.26E-84 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS08605 9fa672c73688ce1e8c993d1e22a5c68c 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 146 165 6.7E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS08605 9fa672c73688ce1e8c993d1e22a5c68c 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 183 196 6.7E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS08605 9fa672c73688ce1e8c993d1e22a5c68c 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 381 397 6.7E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS08605 9fa672c73688ce1e8c993d1e22a5c68c 442 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 382 392 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CXR48_RS08605 9fa672c73688ce1e8c993d1e22a5c68c 442 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 151 161 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CXR48_RS08605 9fa672c73688ce1e8c993d1e22a5c68c 442 Gene3D G3DSA:3.40.50.200 96 442 3.9E-91 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS08605 9fa672c73688ce1e8c993d1e22a5c68c 442 Pfam PF00082 Subtilase family 146 431 3.0E-57 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS08605 9fa672c73688ce1e8c993d1e22a5c68c 442 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 187 197 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CXR48_RS15860 2576c8056676e7f980ab4d1d542d7cc8 105 SUPERFAMILY SSF46785 2 103 1.36E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15860 2576c8056676e7f980ab4d1d542d7cc8 105 Gene3D G3DSA:1.10.10.10 14 103 1.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15860 2576c8056676e7f980ab4d1d542d7cc8 105 Pfam PF01638 HxlR-like helix-turn-helix 16 104 3.9E-34 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CXR48_RS13785 2128a27e7155aa7faee6233eee49a73e 229 Gene3D G3DSA:3.30.1330.60 68 229 7.1E-37 T 29-03-2018 IPR006665 OmpA-like domain CXR48_RS13785 2128a27e7155aa7faee6233eee49a73e 229 Pfam PF00691 OmpA family 118 217 1.1E-18 T 29-03-2018 IPR006665 OmpA-like domain CXR48_RS13785 2128a27e7155aa7faee6233eee49a73e 229 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 11 60 2.2E-20 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CXR48_RS13785 2128a27e7155aa7faee6233eee49a73e 229 SUPERFAMILY SSF103088 106 223 3.4E-28 T 29-03-2018 IPR006665 OmpA-like domain CXR48_RS16365 b7dd3c2a393bb5c90905bbf9e572fb98 85 SUPERFAMILY SSF55594 3 84 3.14E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS16365 b7dd3c2a393bb5c90905bbf9e572fb98 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 2.5E-31 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS16365 b7dd3c2a393bb5c90905bbf9e572fb98 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CXR48_RS16365 b7dd3c2a393bb5c90905bbf9e572fb98 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 4.1E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS16365 b7dd3c2a393bb5c90905bbf9e572fb98 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 4.1E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS16365 b7dd3c2a393bb5c90905bbf9e572fb98 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 4.1E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS16365 b7dd3c2a393bb5c90905bbf9e572fb98 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 3.8E-31 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS16365 b7dd3c2a393bb5c90905bbf9e572fb98 85 Gene3D G3DSA:3.30.1340.10 1 82 1.7E-33 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CXR48_RS04595 9064731bcb37998225220c84c3fff8d1 131 ProDom PD081567 YHCU 8 116 7.0E-38 T 29-03-2018 IPR020355 Uncharacterised protein family YhcU CXR48_RS04595 9064731bcb37998225220c84c3fff8d1 131 Pfam PF17326 Family of unknown function (DUF5365) 8 117 4.3E-38 T 29-03-2018 IPR020355 Uncharacterised protein family YhcU CXR48_RS05275 5706748fa1e5fd8f7346574db6738d91 1166 Pfam PF12705 PD-(D/E)XK nuclease superfamily 791 1131 3.6E-56 T 29-03-2018 CXR48_RS05275 5706748fa1e5fd8f7346574db6738d91 1166 SUPERFAMILY SSF52540 303 750 9.45E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05275 5706748fa1e5fd8f7346574db6738d91 1166 Gene3D G3DSA:3.90.320.10 696 988 6.3E-8 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CXR48_RS05275 5706748fa1e5fd8f7346574db6738d91 1166 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 2 1162 63.165 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CXR48_RS05275 5706748fa1e5fd8f7346574db6738d91 1166 Gene3D G3DSA:3.40.50.300 1 123 3.8E-28 T 29-03-2018 CXR48_RS05275 5706748fa1e5fd8f7346574db6738d91 1166 Gene3D G3DSA:3.40.50.300 124 269 2.0E-35 T 29-03-2018 CXR48_RS05275 5706748fa1e5fd8f7346574db6738d91 1166 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 2 1163 0.0 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CXR48_RS05275 5706748fa1e5fd8f7346574db6738d91 1166 Gene3D G3DSA:3.40.50.300 270 695 1.6E-30 T 29-03-2018 CXR48_RS02200 5cde49d0d7b0a8d9d1689e913fc052e2 282 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 132 276 4.0E-16 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS02200 5cde49d0d7b0a8d9d1689e913fc052e2 282 Pfam PF00990 Diguanylate cyclase, GGDEF domain 132 277 1.3E-25 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS02200 5cde49d0d7b0a8d9d1689e913fc052e2 282 SUPERFAMILY SSF55073 137 274 1.02E-18 T 29-03-2018 IPR029787 Nucleotide cyclase CXR48_RS02200 5cde49d0d7b0a8d9d1689e913fc052e2 282 SMART SM00267 120 282 3.7E-20 T 29-03-2018 IPR000160 GGDEF domain CXR48_RS02200 5cde49d0d7b0a8d9d1689e913fc052e2 282 Gene3D G3DSA:3.30.70.270 121 281 3.7E-21 T 29-03-2018 CXR48_RS10100 3656257b256a78efbb5d3e3ba41c4c85 85 Pfam PF10819 Protein of unknown function (DUF2564) 9 84 7.6E-26 T 29-03-2018 IPR020314 Uncharacterised protein family YpzA CXR48_RS10100 3656257b256a78efbb5d3e3ba41c4c85 85 ProDom PD062992 CYTOSOLIC YPZA BH2151 12 82 6.0E-23 T 29-03-2018 IPR020314 Uncharacterised protein family YpzA CXR48_RS05185 10c61eaabdfacab3194ef21ec170500e 192 Pfam PF06338 ComK protein 10 158 9.2E-59 T 29-03-2018 IPR010461 Competence protein ComK GO:0030420 CXR48_RS05185 10c61eaabdfacab3194ef21ec170500e 192 PIRSF PIRSF011560 4 191 4.4E-74 T 29-03-2018 IPR010461 Competence protein ComK GO:0030420 CXR48_RS04985 15fd83432c1201e245d14e148fdae79b 203 Pfam PF01047 MarR family 44 101 7.8E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS04985 15fd83432c1201e245d14e148fdae79b 203 Hamap MF_01911 HTH-type transcriptional regulator Hpr [hpr]. 2 185 49.342 T 29-03-2018 IPR023488 HTH-type transcriptional regulator Hpr CXR48_RS04985 15fd83432c1201e245d14e148fdae79b 203 SUPERFAMILY SSF46785 20 131 9.27E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04985 15fd83432c1201e245d14e148fdae79b 203 Gene3D G3DSA:1.10.10.10 2 167 1.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04985 15fd83432c1201e245d14e148fdae79b 203 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CXR48_RS04985 15fd83432c1201e245d14e148fdae79b 203 SMART SM00347 37 137 2.2E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS00305 f4f8fcc26e63d2454a765e06bc7a4222 126 Pfam PF01042 Endoribonuclease L-PSP 7 123 2.9E-48 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CXR48_RS00305 f4f8fcc26e63d2454a765e06bc7a4222 126 SUPERFAMILY SSF55298 2 125 1.48E-47 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CXR48_RS00305 f4f8fcc26e63d2454a765e06bc7a4222 126 Gene3D G3DSA:3.30.1330.40 1 126 1.3E-48 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CXR48_RS00305 f4f8fcc26e63d2454a765e06bc7a4222 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 123 3.2E-56 T 29-03-2018 IPR006056 RidA family CXR48_RS00305 f4f8fcc26e63d2454a765e06bc7a4222 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 100 118 - T 29-03-2018 IPR019897 RidA, conserved site CXR48_RS18795 7c6308382a32c740de77a14b36058c76 139 Pfam PF17369 Family of unknown function (DUF5391) 3 132 1.3E-42 T 29-03-2018 IPR020204 Uncharacterised protein family, YxaJ CXR48_RS18795 7c6308382a32c740de77a14b36058c76 139 ProDom PD086672 YXAJ MEMBRANE TRANSMEMBRANE 5 130 1.0E-14 T 29-03-2018 IPR020204 Uncharacterised protein family, YxaJ CXR48_RS04605 f3d166f76c894a1341c2c9b228ecdab2 229 SUPERFAMILY SSF56784 2 207 3.86E-47 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS04605 f3d166f76c894a1341c2c9b228ecdab2 229 Gene3D G3DSA:3.40.50.1000 1 211 5.1E-38 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS04605 f3d166f76c894a1341c2c9b228ecdab2 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 4.2E-31 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS04605 f3d166f76c894a1341c2c9b228ecdab2 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 60 184 1.4E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS04605 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 7.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS04605 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 7.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS04605 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 7.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS04605 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 7.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS04605 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 186 7.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS18400 147297e3eff0cbb4ff51ca091be99272 280 Gene3D G3DSA:3.20.20.370 24 271 7.7E-55 T 29-03-2018 CXR48_RS18400 147297e3eff0cbb4ff51ca091be99272 280 Pfam PF01522 Polysaccharide deacetylase 114 239 1.7E-38 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CXR48_RS18400 147297e3eff0cbb4ff51ca091be99272 280 SUPERFAMILY SSF88713 78 259 1.43E-46 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CXR48_RS02345 18d301670d836cba274826fc3cb85397 246 Pfam PF12730 ABC-2 family transporter protein 1 173 7.2E-20 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CXR48_RS15200 6ba0b0e6e71f4ce0a9f193e64b8e48c1 294 Gene3D G3DSA:1.10.3720.10 17 281 6.5E-45 T 29-03-2018 CXR48_RS15200 6ba0b0e6e71f4ce0a9f193e64b8e48c1 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 287 2.3E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15200 6ba0b0e6e71f4ce0a9f193e64b8e48c1 294 SUPERFAMILY SSF161098 26 294 4.06E-72 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 SUPERFAMILY SSF51735 5 245 3.14E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 9.9E-5 T 29-03-2018 CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 7.6E-60 T 29-03-2018 CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS09410 5383dbda6a01adc88b35f412ba6a8998 248 Gene3D G3DSA:3.40.50.720 2 248 3.4E-71 T 29-03-2018 CXR48_RS16650 6354a0b1a5b5a82e4944dd4eeb94e249 333 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 3.7E-43 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CXR48_RS16650 6354a0b1a5b5a82e4944dd4eeb94e249 333 Gene3D G3DSA:1.20.1330.10 38 304 2.6E-79 T 29-03-2018 CXR48_RS16650 6354a0b1a5b5a82e4944dd4eeb94e249 333 PRINTS PR00207 Flagellin signature 109 132 5.5E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CXR48_RS16650 6354a0b1a5b5a82e4944dd4eeb94e249 333 PRINTS PR00207 Flagellin signature 35 52 5.5E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CXR48_RS16650 6354a0b1a5b5a82e4944dd4eeb94e249 333 PRINTS PR00207 Flagellin signature 74 93 5.5E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CXR48_RS16650 6354a0b1a5b5a82e4944dd4eeb94e249 333 SUPERFAMILY SSF64518 1 332 3.14E-98 T 29-03-2018 CXR48_RS16650 6354a0b1a5b5a82e4944dd4eeb94e249 333 Pfam PF00700 Bacterial flagellin C-terminal helical region 247 331 2.9E-29 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 SUPERFAMILY SSF101353 246 459 8.11E-69 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 Gene3D G3DSA:1.20.120.330 701 876 1.9E-7 T 29-03-2018 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 SMART SM00863 655 698 1.3E-21 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 Gene3D G3DSA:3.30.930.10 3 242 2.2E-98 T 29-03-2018 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 857 0.0 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 1.5E-18 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 Pfam PF01411 tRNA synthetases class II (A) 8 557 2.8E-219 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 Gene3D G3DSA:3.30.980.10 556 700 1.5E-44 T 29-03-2018 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 SUPERFAMILY SSF55186 554 710 6.02E-52 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 878 187.119 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 4.5E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 4.5E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 4.5E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 4.5E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 4.5E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 Pfam PF02272 DHHA1 domain 735 874 7.1E-30 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 SUPERFAMILY SSF55681 5 245 5.96E-90 T 29-03-2018 CXR48_RS12615 f4421024068ae0770a3ac0ba465deecc 878 SUPERFAMILY SSF50447 455 554 8.42E-19 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CXR48_RS11945 ceb2fa8039ae65f13cae8712b02c940e 69 SUPERFAMILY SSF158379 5 63 1.96E-21 T 29-03-2018 IPR023164 YqgQ-like domain CXR48_RS11945 ceb2fa8039ae65f13cae8712b02c940e 69 Gene3D G3DSA:1.10.287.760 5 68 2.1E-25 T 29-03-2018 IPR023164 YqgQ-like domain CXR48_RS11945 ceb2fa8039ae65f13cae8712b02c940e 69 Pfam PF06014 Bacterial protein of unknown function (DUF910) 5 63 7.3E-25 T 29-03-2018 IPR009256 Protein of unknown function DUF910 CXR48_RS06075 6d0eecc925d0141c6842770f5631bf54 465 Pfam PF02614 Glucuronate isomerase 2 463 8.7E-221 T 29-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 CXR48_RS06075 6d0eecc925d0141c6842770f5631bf54 465 Hamap MF_00675 Uronate isomerase [uxaC]. 2 465 48.249 T 29-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 CXR48_RS06075 6d0eecc925d0141c6842770f5631bf54 465 Gene3D G3DSA:3.20.20.140 90 465 2.1E-143 T 29-03-2018 CXR48_RS06075 6d0eecc925d0141c6842770f5631bf54 465 Gene3D G3DSA:3.20.20.140 3 89 8.0E-28 T 29-03-2018 CXR48_RS06075 6d0eecc925d0141c6842770f5631bf54 465 SUPERFAMILY SSF51556 2 464 1.12E-178 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 SUPERFAMILY SSF48452 188 366 7.49E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 Pfam PF13424 Tetratricopeptide repeat 192 251 2.3E-9 T 29-03-2018 CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 SUPERFAMILY SSF48452 99 209 2.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 SMART SM00028 259 292 13.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 SMART SM00028 334 367 300.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 SMART SM00028 180 213 430.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 SMART SM00028 220 253 1.4E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 SMART SM00028 99 132 39.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 Gene3D G3DSA:1.25.40.10 2 151 5.8E-29 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17345 56e6bfaecfb0658bd7bf36ad10486a3e 376 Gene3D G3DSA:1.25.40.10 152 373 1.5E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS19160 476614013d3f7f82b63fb0a784cab3ff 309 Pfam PF02833 DHHA2 domain 183 306 1.3E-23 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CXR48_RS19160 476614013d3f7f82b63fb0a784cab3ff 309 Gene3D G3DSA:3.90.1640.10 1 188 1.3E-71 T 29-03-2018 CXR48_RS19160 476614013d3f7f82b63fb0a784cab3ff 309 SUPERFAMILY SSF64182 1 307 9.16E-87 T 29-03-2018 CXR48_RS19160 476614013d3f7f82b63fb0a784cab3ff 309 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 49.16 T 29-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CXR48_RS19160 476614013d3f7f82b63fb0a784cab3ff 309 Pfam PF01368 DHH family 3 146 3.7E-32 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CXR48_RS19160 476614013d3f7f82b63fb0a784cab3ff 309 SMART SM01131 181 307 2.8E-60 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CXR48_RS19170 12cba1791fd244cf30af108ed0822273 473 SUPERFAMILY SSF75005 35 472 3.85E-109 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS19170 12cba1791fd244cf30af108ed0822273 473 Pfam PF02435 Levansucrase/Invertase 40 469 1.8E-167 T 29-03-2018 IPR003469 Glycoside hydrolase, family 68 GO:0009758|GO:0050053 CXR48_RS19170 12cba1791fd244cf30af108ed0822273 473 Gene3D G3DSA:2.115.10.20 27 467 9.3E-102 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS16800 cec1d1848ab711a00a405bec710a1f85 379 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 363 1.3E-119 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CXR48_RS16800 cec1d1848ab711a00a405bec710a1f85 379 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 366 5.1E-171 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CXR48_RS16800 cec1d1848ab711a00a405bec710a1f85 379 Gene3D G3DSA:3.40.50.2000 205 350 5.7E-39 T 29-03-2018 CXR48_RS16800 cec1d1848ab711a00a405bec710a1f85 379 SUPERFAMILY SSF53756 3 370 1.39E-136 T 29-03-2018 CXR48_RS16800 cec1d1848ab711a00a405bec710a1f85 379 Gene3D G3DSA:3.40.50.2000 4 204 1.2E-76 T 29-03-2018 CXR48_RS13235 6736f39154789a7863c33e931cfdeab8 248 Gene3D G3DSA:3.30.1330.30 3 97 7.4E-23 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CXR48_RS13235 6736f39154789a7863c33e931cfdeab8 248 Gene3D G3DSA:3.40.1280.10 98 248 4.3E-40 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CXR48_RS13235 6736f39154789a7863c33e931cfdeab8 248 SUPERFAMILY SSF75217 98 247 1.18E-39 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CXR48_RS13235 6736f39154789a7863c33e931cfdeab8 248 SUPERFAMILY SSF55315 2 97 1.29E-21 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CXR48_RS13235 6736f39154789a7863c33e931cfdeab8 248 Pfam PF00588 SpoU rRNA Methylase family 107 244 8.6E-34 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CXR48_RS13235 6736f39154789a7863c33e931cfdeab8 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 97 4.4E-7 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CXR48_RS13235 6736f39154789a7863c33e931cfdeab8 248 SMART SM00967 31 99 3.8E-11 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CXR48_RS13370 09f489f0bc401b9633e8a9d684f59ea8 264 Gene3D G3DSA:3.40.50.1000 111 264 3.3E-31 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS13370 09f489f0bc401b9633e8a9d684f59ea8 264 SUPERFAMILY SSF56784 95 259 2.36E-41 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS13370 09f489f0bc401b9633e8a9d684f59ea8 264 SUPERFAMILY SSF56784 1 62 2.36E-41 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS13370 09f489f0bc401b9633e8a9d684f59ea8 264 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 225 3.5E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS13370 09f489f0bc401b9633e8a9d684f59ea8 264 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 231 9.8E-23 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS13370 09f489f0bc401b9633e8a9d684f59ea8 264 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 134 231 1.8E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 Pfam PF01336 OB-fold nucleic acid binding domain 16 95 7.8E-16 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 Gene3D G3DSA:3.30.930.10 101 430 8.7E-94 T 29-03-2018 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 430 42.252 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 SUPERFAMILY SSF50249 9 102 8.78E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 4.8E-85 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 Gene3D G3DSA:2.40.50.140 1 100 2.2E-21 T 29-03-2018 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 2 429 5.6E-174 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 8.1E-15 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 8.1E-15 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 8.1E-15 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 8.1E-15 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CXR48_RS10590 15fc181c01eba184a4e4a10efa27043b 430 SUPERFAMILY SSF55681 110 424 2.7E-97 T 29-03-2018 CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.1E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.1E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 Gene3D G3DSA:3.40.50.1360 73 243 1.8E-36 T 29-03-2018 CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 SUPERFAMILY SSF100950 75 230 2.51E-31 T 29-03-2018 CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 SMART SM01134 73 233 6.1E-63 T 29-03-2018 CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 SMART SM00420 6 58 4.9E-19 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 Gene3D G3DSA:1.10.10.10 6 72 1.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 Pfam PF00455 DeoR C terminal sensor domain 75 231 3.1E-47 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 4.4E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS07100 dcc07bf12d9e37f067dd7c14fc037f47 251 SUPERFAMILY SSF46785 5 68 3.77E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09610 2b378db610aa1f8c68b3972de0fbf598 208 Pfam PF10372 Bacterial membrane-spanning protein N-terminus 5 70 6.4E-22 T 29-03-2018 IPR019457 Uncharacterised domain YojJ, N-terminal CXR48_RS09610 2b378db610aa1f8c68b3972de0fbf598 208 Gene3D G3DSA:3.40.1700.10 73 199 4.9E-34 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CXR48_RS09610 2b378db610aa1f8c68b3972de0fbf598 208 Hamap MF_00838 Diadenylate cyclase [dacB]. 15 201 35.027 T 29-03-2018 IPR034693 Diadenylate cyclase CdaS GO:0004016|GO:0006171 CXR48_RS09610 2b378db610aa1f8c68b3972de0fbf598 208 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 79 194 5.6E-40 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CXR48_RS09610 2b378db610aa1f8c68b3972de0fbf598 208 Gene3D G3DSA:1.10.287.770 9 70 2.4E-22 T 29-03-2018 CXR48_RS09610 2b378db610aa1f8c68b3972de0fbf598 208 SUPERFAMILY SSF143597 14 199 1.7E-51 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CXR48_RS09610 2b378db610aa1f8c68b3972de0fbf598 208 PIRSF PIRSF004793 1 208 1.4E-64 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CXR48_RS15115 85b79c65fbdb12133f4f2cac58ff11c1 252 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 139 228 5.0E-30 T 29-03-2018 IPR014197 Sporulation protein YunB CXR48_RS15115 85b79c65fbdb12133f4f2cac58ff11c1 252 PIRSF PIRSF021383 1 245 3.0E-107 T 29-03-2018 IPR014197 Sporulation protein YunB CXR48_RS15115 85b79c65fbdb12133f4f2cac58ff11c1 252 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 14 232 1.2E-70 T 29-03-2018 IPR014197 Sporulation protein YunB CXR48_RS02950 7e91588b489efd18f1fb5a1328a7d7eb 109 Pfam PF00893 Small Multidrug Resistance protein 1 89 3.3E-21 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CXR48_RS02950 7e91588b489efd18f1fb5a1328a7d7eb 109 SUPERFAMILY SSF103481 5 99 6.93E-12 T 29-03-2018 CXR48_RS18710 11de1a4dd2b011a5eeea10145c34602e 298 SUPERFAMILY SSF51658 7 290 4.01E-55 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS18710 11de1a4dd2b011a5eeea10145c34602e 298 Hamap MF_01672 Inosose dehydratase [iolE]. 1 295 56.78 T 29-03-2018 IPR023952 Inosose dehydratase GO:0019310|GO:0030145|GO:0050114 KEGG: 00562+4.2.1.44 CXR48_RS18710 11de1a4dd2b011a5eeea10145c34602e 298 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 6 291 3.7E-119 T 29-03-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 CXR48_RS18710 11de1a4dd2b011a5eeea10145c34602e 298 Pfam PF01261 Xylose isomerase-like TIM barrel 55 226 2.9E-24 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS18710 11de1a4dd2b011a5eeea10145c34602e 298 Gene3D G3DSA:3.20.20.150 1 294 3.7E-51 T 29-03-2018 CXR48_RS00085 07b8083854053811a49ffa858dff6b28 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 4 185 9.4E-84 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00085 07b8083854053811a49ffa858dff6b28 196 Pfam PF01174 SNO glutamine amidotransferase family 6 188 1.1E-81 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00085 07b8083854053811a49ffa858dff6b28 196 Gene3D G3DSA:3.40.50.880 1 196 1.4E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS00085 07b8083854053811a49ffa858dff6b28 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 37.264 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00085 07b8083854053811a49ffa858dff6b28 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 29-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00085 07b8083854053811a49ffa858dff6b28 196 PIRSF PIRSF005639 1 191 8.7E-74 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CXR48_RS00085 07b8083854053811a49ffa858dff6b28 196 SUPERFAMILY SSF52317 3 188 6.53E-54 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS17955 ca6b32f05d6d9281ae51e34b02590a46 439 Pfam PF00860 Permease family 2 390 2.0E-84 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS17955 ca6b32f05d6d9281ae51e34b02590a46 439 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 336 356 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CXR48_RS14585 8e43d37565b9fcd2d4ad71549986cbb9 214 SUPERFAMILY SSF52499 5 204 1.22E-53 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS14585 8e43d37565b9fcd2d4ad71549986cbb9 214 Pfam PF00857 Isochorismatase family 14 165 4.6E-23 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS14585 8e43d37565b9fcd2d4ad71549986cbb9 214 Gene3D G3DSA:3.40.50.850 1 209 4.2E-40 T 29-03-2018 CXR48_RS01975 f8d52d9776ac0d4162f31ceae4923b9d 315 Gene3D G3DSA:1.10.3470.10 6 315 3.4E-39 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS01975 f8d52d9776ac0d4162f31ceae4923b9d 315 Pfam PF01032 FecCD transport family 36 310 8.1E-53 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CXR48_RS01975 f8d52d9776ac0d4162f31ceae4923b9d 315 SUPERFAMILY SSF81345 6 310 5.75E-58 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 SUPERFAMILY SSF51735 3 199 7.88E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 148 354 4.5E-54 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 2 122 6.1E-26 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 SUPERFAMILY SSF48179 201 357 2.24E-41 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 149 161 - T 29-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 1.1E-20 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 PRINTS PR00084 Mannitol dehydrogenase signature 149 162 1.1E-20 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 PRINTS PR00084 Mannitol dehydrogenase signature 113 126 1.1E-20 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 PRINTS PR00084 Mannitol dehydrogenase signature 167 182 1.1E-20 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 Gene3D G3DSA:3.40.50.720 2 75 1.9E-7 T 29-03-2018 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 Gene3D G3DSA:3.40.50.720 76 199 3.7E-26 T 29-03-2018 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 371 40.462 T 29-03-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CXR48_RS02070 520f79d02ff8589a6ec44193478b2424 373 Gene3D G3DSA:1.10.1040.10 200 372 5.4E-39 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS18895 75262e8a0c93ef20ee2d2115ad34bcf1 159 SUPERFAMILY SSF75217 2 157 1.36E-63 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CXR48_RS18895 75262e8a0c93ef20ee2d2115ad34bcf1 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 159 7.6E-79 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS18895 75262e8a0c93ef20ee2d2115ad34bcf1 159 PIRSF PIRSF004505 1 159 2.2E-54 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS18895 75262e8a0c93ef20ee2d2115ad34bcf1 159 Pfam PF02590 Predicted SPOUT methyltransferase 2 158 9.8E-60 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS18895 75262e8a0c93ef20ee2d2115ad34bcf1 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.804 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS18895 75262e8a0c93ef20ee2d2115ad34bcf1 159 Gene3D G3DSA:3.40.1280.10 1 159 6.0E-63 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 SMART SM00936 280 371 1.2E-25 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 63 74 8.3E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 8.3E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 8.3E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 SUPERFAMILY SSF56601 1 280 7.92E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 280 371 1.2E-18 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 SUPERFAMILY SSF69189 280 373 1.02E-21 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 260 6.8E-92 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 Gene3D G3DSA:2.60.410.10 280 371 9.5E-21 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS11135 5fc193c886bfce80e653a1fc017534ef 389 Gene3D G3DSA:3.40.710.10 25 279 4.1E-49 T 29-03-2018 CXR48_RS04655 0f134cce7f59a4d57b2a1579aa8e5a8d 174 Pfam PF03358 NADPH-dependent FMN reductase 1 135 1.4E-31 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CXR48_RS04655 0f134cce7f59a4d57b2a1579aa8e5a8d 174 SUPERFAMILY SSF52218 1 168 2.48E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS04655 0f134cce7f59a4d57b2a1579aa8e5a8d 174 Gene3D G3DSA:3.40.50.360 1 174 3.7E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS05395 267d41cbd987f772ff519f04cd574914 208 Pfam PF00805 Pentapeptide repeats (8 copies) 51 85 0.0011 T 29-03-2018 IPR001646 Pentapeptide repeat CXR48_RS05395 267d41cbd987f772ff519f04cd574914 208 Pfam PF13599 Pentapeptide repeats (9 copies) 110 178 4.0E-10 T 29-03-2018 IPR001646 Pentapeptide repeat CXR48_RS05395 267d41cbd987f772ff519f04cd574914 208 Gene3D G3DSA:2.160.10.20 111 199 3.4E-12 T 29-03-2018 CXR48_RS05395 267d41cbd987f772ff519f04cd574914 208 Gene3D G3DSA:2.160.10.20 20 110 1.4E-11 T 29-03-2018 CXR48_RS05395 267d41cbd987f772ff519f04cd574914 208 SUPERFAMILY SSF141571 37 207 3.4E-37 T 29-03-2018 CXR48_RS03945 00f0c164180f644e2008dda269629544 466 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 394 425 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site CXR48_RS03945 00f0c164180f644e2008dda269629544 466 Gene3D G3DSA:2.40.50.140 2 83 3.9E-24 T 29-03-2018 CXR48_RS03945 00f0c164180f644e2008dda269629544 466 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 445 455 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CXR48_RS03945 00f0c164180f644e2008dda269629544 466 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 219 457 3.9E-20 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CXR48_RS03945 00f0c164180f644e2008dda269629544 466 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 25 455 1.9E-199 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CXR48_RS03945 00f0c164180f644e2008dda269629544 466 SUPERFAMILY SSF50249 6 68 1.2E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS03945 00f0c164180f644e2008dda269629544 466 Gene3D G3DSA:3.40.50.150 84 151 2.7E-12 T 29-03-2018 CXR48_RS03945 00f0c164180f644e2008dda269629544 466 Gene3D G3DSA:3.40.50.150 200 461 1.7E-46 T 29-03-2018 CXR48_RS03945 00f0c164180f644e2008dda269629544 466 Pfam PF01938 TRAM domain 13 67 2.4E-11 T 29-03-2018 IPR002792 TRAM domain CXR48_RS03945 00f0c164180f644e2008dda269629544 466 SUPERFAMILY SSF53335 77 460 6.0E-78 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS16525 e1c9aeadce417069a8818dfd56cb36ec 365 Pfam PF13349 Putative adhesin 110 353 1.4E-19 T 29-03-2018 IPR025164 Putative adhesin CXR48_RS16525 e1c9aeadce417069a8818dfd56cb36ec 365 PIRSF PIRSF012569 1 365 9.8E-129 T 29-03-2018 IPR016599 Uncharacterised conserved protein UCP012569 CXR48_RS11620 dc985a534745cc8a67354ec8ff4fb627 70 Pfam PF10676 Spore germination protein gerPA/gerPF 5 67 8.6E-18 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CXR48_RS08810 473df93f671f5d3b965723630980fafd 357 Pfam PF00296 Luciferase-like monooxygenase 10 312 8.2E-53 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS08810 473df93f671f5d3b965723630980fafd 357 SUPERFAMILY SSF51679 9 350 8.9E-75 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS08810 473df93f671f5d3b965723630980fafd 357 Gene3D G3DSA:3.20.20.30 1 357 2.3E-74 T 29-03-2018 CXR48_RS14735 23ff4689d339800109b0f4cd48e27ad6 94 PIRSF PIRSF028784 1 92 1.1E-33 T 29-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CXR48_RS14735 23ff4689d339800109b0f4cd48e27ad6 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 83 5.6E-20 T 29-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CXR48_RS17130 e36c19e1d1fe711ac87e1aa8df576b5f 254 SUPERFAMILY SSF89550 1 210 5.1E-20 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CXR48_RS17130 e36c19e1d1fe711ac87e1aa8df576b5f 254 PIRSF PIRSF016557 1 254 1.2E-96 T 29-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 CXR48_RS17130 e36c19e1d1fe711ac87e1aa8df576b5f 254 Gene3D G3DSA:3.20.20.140 1 243 2.2E-25 T 29-03-2018 CXR48_RS06740 1025316abe712d668efe3e03e5a449f2 223 SUPERFAMILY SSF56784 1 217 6.89E-56 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS06740 1025316abe712d668efe3e03e5a449f2 223 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 5 187 3.7E-63 T 29-03-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 CXR48_RS06740 1025316abe712d668efe3e03e5a449f2 223 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 3 217 49.793 T 29-03-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 CXR48_RS06740 1025316abe712d668efe3e03e5a449f2 223 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 178 5.3E-18 T 29-03-2018 CXR48_RS06740 1025316abe712d668efe3e03e5a449f2 223 Gene3D G3DSA:3.40.50.1000 1 215 6.4E-15 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS06740 1025316abe712d668efe3e03e5a449f2 223 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 179 1.5E-42 T 29-03-2018 CXR48_RS06740 1025316abe712d668efe3e03e5a449f2 223 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 6 219 7.1E-116 T 29-03-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 CXR48_RS03165 f5b3bb0452fdaab9fe6750a378c28ff7 286 Gene3D G3DSA:3.90.640.20 187 286 5.0E-27 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CXR48_RS03165 f5b3bb0452fdaab9fe6750a378c28ff7 286 Pfam PF11738 Protein of unknown function (DUF3298) 190 273 6.3E-20 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CXR48_RS03165 f5b3bb0452fdaab9fe6750a378c28ff7 286 Gene3D G3DSA:3.30.565.40 75 186 5.4E-14 T 29-03-2018 CXR48_RS03165 f5b3bb0452fdaab9fe6750a378c28ff7 286 Pfam PF13739 Domain of unknown function (DUF4163) 86 160 8.8E-7 T 29-03-2018 IPR025303 Deacetylase PdaC CXR48_RS17745 1ef96e374f3198afec814771957f7875 139 SMART SM00347 27 127 2.8E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS17745 1ef96e374f3198afec814771957f7875 139 Gene3D G3DSA:1.10.10.10 3 130 9.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17745 1ef96e374f3198afec814771957f7875 139 Pfam PF01047 MarR family 40 92 5.9E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS17745 1ef96e374f3198afec814771957f7875 139 SUPERFAMILY SSF46785 20 138 4.41E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17745 1ef96e374f3198afec814771957f7875 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 6.9E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS17745 1ef96e374f3198afec814771957f7875 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 6.9E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS17745 1ef96e374f3198afec814771957f7875 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 6.9E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS10825 279acd1fbcc779932d4bb1975abeb7cb 67 Pfam PF10966 Protein of unknown function (DUF2768) 7 64 6.3E-25 T 29-03-2018 IPR020076 Protein of unknown function DUF2768 CXR48_RS10825 279acd1fbcc779932d4bb1975abeb7cb 67 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 67 2.0E-22 T 29-03-2018 IPR020076 Protein of unknown function DUF2768 CXR48_RS09640 b047590b340e951bf5d89ba4dd4022d1 298 Pfam PF00892 EamA-like transporter family 156 285 8.4E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS09640 b047590b340e951bf5d89ba4dd4022d1 298 Pfam PF00892 EamA-like transporter family 8 146 1.9E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS09640 b047590b340e951bf5d89ba4dd4022d1 298 SUPERFAMILY SSF103481 209 288 1.44E-9 T 29-03-2018 CXR48_RS09640 b047590b340e951bf5d89ba4dd4022d1 298 TIGRFAM TIGR00688 rarD: protein RarD 8 262 1.4E-102 T 29-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CXR48_RS09640 b047590b340e951bf5d89ba4dd4022d1 298 SUPERFAMILY SSF103481 42 147 6.8E-10 T 29-03-2018 CXR48_RS12690 6674dc09f03e946bf2925acb6d9aad39 254 SUPERFAMILY SSF69572 4 245 1.96E-63 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CXR48_RS12690 6674dc09f03e946bf2925acb6d9aad39 254 Gene3D G3DSA:3.40.50.720 2 252 5.4E-47 T 29-03-2018 CXR48_RS12690 6674dc09f03e946bf2925acb6d9aad39 254 Pfam PF00899 ThiF family 6 158 7.2E-40 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CXR48_RS16930 139752baa825ee6aff2cbde96bdbbe6c 363 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 358 1.6E-59 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CXR48_RS16930 139752baa825ee6aff2cbde96bdbbe6c 363 Pfam PF03845 Spore germination protein 5 321 4.4E-54 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CXR48_RS12010 15250ecbd21e54ce4ef9016a88ff963c 429 SUPERFAMILY SSF103473 14 398 6.45E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS12010 15250ecbd21e54ce4ef9016a88ff963c 429 Gene3D G3DSA:1.20.1250.20 2 201 3.1E-20 T 29-03-2018 CXR48_RS12010 15250ecbd21e54ce4ef9016a88ff963c 429 Pfam PF07690 Major Facilitator Superfamily 62 329 1.5E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS12010 15250ecbd21e54ce4ef9016a88ff963c 429 Gene3D G3DSA:1.20.1250.20 215 415 1.8E-9 T 29-03-2018 CXR48_RS08095 7089fe052def4667723f5f60546453e1 438 SUPERFAMILY SSF52540 92 359 9.83E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08095 7089fe052def4667723f5f60546453e1 438 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 354 9.2E-77 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS08095 7089fe052def4667723f5f60546453e1 438 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 13 434 3.3E-206 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS08095 7089fe052def4667723f5f60546453e1 438 SMART SM00382 157 338 5.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS08095 7089fe052def4667723f5f60546453e1 438 Gene3D G3DSA:3.40.50.300 55 354 1.7E-84 T 29-03-2018 CXR48_RS08095 7089fe052def4667723f5f60546453e1 438 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS08095 7089fe052def4667723f5f60546453e1 438 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 22 88 2.2E-5 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS08095 7089fe052def4667723f5f60546453e1 438 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 20 433 1.1E-206 T 29-03-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CXR48_RS12450 f8039f413d1236a156b1d811fee81068 315 Gene3D G3DSA:2.60.120.10 238 315 2.4E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS12450 f8039f413d1236a156b1d811fee81068 315 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 101 314 6.7E-57 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CXR48_RS12450 f8039f413d1236a156b1d811fee81068 315 Pfam PF01238 Phosphomannose isomerase type I 9 196 1.7E-39 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CXR48_RS12450 f8039f413d1236a156b1d811fee81068 315 SUPERFAMILY SSF51182 4 314 5.13E-106 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS12450 f8039f413d1236a156b1d811fee81068 315 Gene3D G3DSA:2.60.120.10 1 223 4.1E-61 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS12450 f8039f413d1236a156b1d811fee81068 315 PIRSF PIRSF036894 3 315 4.5E-131 T 29-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CXR48_RS09445 79d1becb639e2bcd7f63a1b0c9f71bf0 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 59 7.4E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS09445 79d1becb639e2bcd7f63a1b0c9f71bf0 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 7.4E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS09445 79d1becb639e2bcd7f63a1b0c9f71bf0 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 44 7.4E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS09445 79d1becb639e2bcd7f63a1b0c9f71bf0 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 7.4E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS09445 79d1becb639e2bcd7f63a1b0c9f71bf0 110 Pfam PF01022 Bacterial regulatory protein, arsR family 34 80 2.5E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS09445 79d1becb639e2bcd7f63a1b0c9f71bf0 110 SMART SM00418 27 105 4.7E-36 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS09445 79d1becb639e2bcd7f63a1b0c9f71bf0 110 Gene3D G3DSA:1.10.10.10 2 110 4.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09445 79d1becb639e2bcd7f63a1b0c9f71bf0 110 SUPERFAMILY SSF46785 15 108 4.17E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS00915 cc669be9f9d90df0381ecd01c5686a7e 255 Gene3D G3DSA:3.40.50.150 50 221 4.3E-16 T 29-03-2018 CXR48_RS00915 cc669be9f9d90df0381ecd01c5686a7e 255 SUPERFAMILY SSF53335 48 233 1.59E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS00915 cc669be9f9d90df0381ecd01c5686a7e 255 Pfam PF08241 Methyltransferase domain 63 158 4.7E-14 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 Gene3D G3DSA:1.10.101.10 377 451 8.7E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 SMART SM00228 104 175 4.8E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 55 381 8.7E-123 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 SMART SM00245 176 364 1.5E-77 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 104 171 3.7E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 Gene3D G3DSA:3.30.750.44 27 103 4.4E-18 T 29-03-2018 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 Pfam PF03572 Peptidase family S41 201 363 1.3E-49 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 SUPERFAMILY SSF50156 94 175 1.23E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 SUPERFAMILY SSF52096 40 122 1.82E-71 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 SUPERFAMILY SSF52096 195 368 1.82E-71 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 SUPERFAMILY SSF47090 375 444 5.63E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 Gene3D G3DSA:2.30.42.10 104 184 4.9E-21 T 29-03-2018 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 Gene3D G3DSA:3.90.226.10 185 376 1.4E-58 T 29-03-2018 CXR48_RS09710 7aa5c9732811e74ecb059ad7aadfcafa 467 Pfam PF01471 Putative peptidoglycan binding domain 386 440 2.1E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS01640 ead4d8df8ebdd61b87814763b6782bb4 253 Pfam PF08892 YqcI/YcgG family 37 243 2.3E-74 T 29-03-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 SUPERFAMILY SSF52540 1 240 5.32E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 SUPERFAMILY SSF54631 251 374 5.37E-28 T 29-03-2018 CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 Pfam PF00005 ABC transporter 19 163 4.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 Pfam PF00571 CBS domain 312 364 4.3E-8 T 29-03-2018 IPR000644 CBS domain CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 Pfam PF00571 CBS domain 252 298 3.2E-9 T 29-03-2018 IPR000644 CBS domain CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 Gene3D G3DSA:3.40.50.300 1 253 6.0E-80 T 29-03-2018 CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 SMART SM00382 27 213 3.5E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 12 372 1.2E-172 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 SMART SM00116 319 367 5.0E-6 T 29-03-2018 IPR000644 CBS domain CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 SMART SM00116 259 307 1.6E-6 T 29-03-2018 IPR000644 CBS domain CXR48_RS15905 0cd5551ff775ce88d279f13fa7b43d78 381 Gene3D G3DSA:3.10.580.10 254 380 2.8E-26 T 29-03-2018 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 SUPERFAMILY SSF55785 212 307 5.86E-6 T 29-03-2018 IPR000014 PAS domain CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 Gene3D G3DSA:3.30.450.20 32 172 1.8E-17 T 29-03-2018 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 SUPERFAMILY SSF55874 398 527 1.7E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 Pfam PF13596 PAS domain 219 310 9.4E-5 T 29-03-2018 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 Pfam PF17203 Single cache domain 3 40 163 7.3E-18 T 29-03-2018 IPR033463 Single cache domain 3 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 319 359 1.9E-9 T 29-03-2018 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 SUPERFAMILY SSF103190 40 168 8.63E-31 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 SUPERFAMILY SSF55890 320 374 1.83E-11 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 SMART SM00091 213 278 2.5E-5 T 29-03-2018 IPR000014 PAS domain CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 Gene3D G3DSA:1.10.287.130 313 372 3.9E-16 T 29-03-2018 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 SMART SM00387 417 528 1.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 Gene3D G3DSA:3.30.450.20 213 312 3.3E-10 T 29-03-2018 CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 422 526 9.6E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02320 68451a0becbe680cfb5a6b3b8ca0384e 540 Gene3D G3DSA:3.30.565.10 373 538 3.4E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS12565 4bbf4f7a80d38a42d6829925168e524f 584 SUPERFAMILY SSF56519 50 223 3.14E-20 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS12565 4bbf4f7a80d38a42d6829925168e524f 584 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 219 1.9E-5 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS12565 4bbf4f7a80d38a42d6829925168e524f 584 Gene3D G3DSA:3.40.710.10 242 584 3.1E-66 T 29-03-2018 CXR48_RS12565 4bbf4f7a80d38a42d6829925168e524f 584 SUPERFAMILY SSF56601 424 579 4.7E-62 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS12565 4bbf4f7a80d38a42d6829925168e524f 584 SUPERFAMILY SSF56601 188 390 4.7E-62 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS12565 4bbf4f7a80d38a42d6829925168e524f 584 Gene3D G3DSA:3.90.1310.10 19 232 2.5E-18 T 29-03-2018 CXR48_RS12565 4bbf4f7a80d38a42d6829925168e524f 584 Pfam PF00905 Penicillin binding protein transpeptidase domain 263 573 9.8E-59 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS07545 b467df76031bc5f83b770b1d001821e0 143 SUPERFAMILY SSF89447 1 136 1.05E-52 T 29-03-2018 CXR48_RS07545 b467df76031bc5f83b770b1d001821e0 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 59.742 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CXR48_RS07545 b467df76031bc5f83b770b1d001821e0 143 Gene3D G3DSA:2.10.260.10 74 120 0.0016 T 29-03-2018 CXR48_RS07545 b467df76031bc5f83b770b1d001821e0 143 Gene3D G3DSA:2.10.260.10 1 63 5.8E-7 T 29-03-2018 CXR48_RS07545 b467df76031bc5f83b770b1d001821e0 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 143 4.9E-66 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CXR48_RS07545 b467df76031bc5f83b770b1d001821e0 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 2.0E-76 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CXR48_RS07545 b467df76031bc5f83b770b1d001821e0 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 5.0E-27 T 29-03-2018 IPR020603 MraZ domain CXR48_RS07545 b467df76031bc5f83b770b1d001821e0 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 4.5E-24 T 29-03-2018 IPR020603 MraZ domain CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 Pfam PF00155 Aminotransferase class I and II 105 452 1.2E-27 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 SMART SM00345 18 77 2.2E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 Gene3D G3DSA:3.90.1150.10 363 459 3.0E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 SUPERFAMILY SSF53383 75 458 5.84E-77 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 3.7E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 3.7E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 Gene3D G3DSA:3.40.640.10 119 362 3.2E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 Gene3D G3DSA:1.10.10.10 2 78 1.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 SUPERFAMILY SSF46785 8 84 9.49E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02740 cdcc1fc8c6f2788e37333de10263c0b5 460 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.2E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS00675 f3db6aae06be1e6e18c86e6dc50f4ed3 166 Pfam PF00466 Ribosomal protein L10 6 101 1.9E-30 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CXR48_RS00675 f3db6aae06be1e6e18c86e6dc50f4ed3 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 29.248 T 29-03-2018 IPR022973 Ribosomal protein L10 CXR48_RS00675 f3db6aae06be1e6e18c86e6dc50f4ed3 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00675 f3db6aae06be1e6e18c86e6dc50f4ed3 166 SUPERFAMILY SSF160369 6 160 3.27E-55 T 29-03-2018 CXR48_RS15750 23eff02517784d61d77c4f17e4272c55 346 Gene3D G3DSA:3.40.50.720 1 129 9.2E-32 T 29-03-2018 CXR48_RS15750 23eff02517784d61d77c4f17e4272c55 346 SUPERFAMILY SSF51735 2 201 2.26E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15750 23eff02517784d61d77c4f17e4272c55 346 Gene3D G3DSA:3.30.360.10 130 346 9.7E-39 T 29-03-2018 CXR48_RS15750 23eff02517784d61d77c4f17e4272c55 346 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 4.4E-22 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CXR48_RS15750 23eff02517784d61d77c4f17e4272c55 346 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 240 5.7E-17 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 SUPERFAMILY SSF101386 114 202 3.92E-28 T 29-03-2018 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 52 101 3.0E-21 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 5 203 37.898 T 29-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 SUPERFAMILY SSF141734 4 106 1.96E-45 T 29-03-2018 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 3 106 28.44 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 115 198 2.1E-32 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 115 202 6.8E-19 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 Gene3D G3DSA:1.10.287.1080 111 204 1.9E-24 T 29-03-2018 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 112 198 20.991 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CXR48_RS16425 5d8b94fee311cfaf3b12233a8eb1282a 206 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 30 101 2.4E-33 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CXR48_RS12545 16f52591a41411187d67550ff97f667a 231 Gene3D G3DSA:3.40.50.1580 1 231 5.0E-58 T 29-03-2018 CXR48_RS12545 16f52591a41411187d67550ff97f667a 231 SUPERFAMILY SSF53167 1 229 4.45E-72 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CXR48_RS12545 16f52591a41411187d67550ff97f667a 231 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 47.748 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS12545 16f52591a41411187d67550ff97f667a 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 230 1.8E-133 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CXR48_RS12545 16f52591a41411187d67550ff97f667a 231 Pfam PF01048 Phosphorylase superfamily 2 227 6.4E-52 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CXR48_RS08795 7d2b66a9ac7d819d88d8ac4b6cb4506e 253 Gene3D G3DSA:3.40.630.30 5 156 4.6E-8 T 29-03-2018 CXR48_RS08795 7d2b66a9ac7d819d88d8ac4b6cb4506e 253 SUPERFAMILY SSF55729 73 144 4.75E-9 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS08795 7d2b66a9ac7d819d88d8ac4b6cb4506e 253 Pfam PF00583 Acetyltransferase (GNAT) family 40 134 4.2E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS08795 7d2b66a9ac7d819d88d8ac4b6cb4506e 253 SUPERFAMILY SSF52833 170 251 3.64E-5 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS08795 7d2b66a9ac7d819d88d8ac4b6cb4506e 253 Pfam PF14268 YoaP-like 203 245 1.3E-16 T 29-03-2018 IPR025685 YoaP-like domain CXR48_RS01440 5519d3700e3b7c3240bb5aaf16a6f590 65 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 47 7.4E-17 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CXR48_RS01440 5519d3700e3b7c3240bb5aaf16a6f590 65 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 1.7E-5 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CXR48_RS01440 5519d3700e3b7c3240bb5aaf16a6f590 65 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 1.7E-5 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CXR48_RS01440 5519d3700e3b7c3240bb5aaf16a6f590 65 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 64 16.758 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CXR48_RS01440 5519d3700e3b7c3240bb5aaf16a6f590 65 Pfam PF02416 mttA/Hcf106 family 5 54 6.7E-21 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CXR48_RS14815 54cd04bdb3d36e92ef82372a5d93d745 78 Pfam PF10842 Protein of unknown function (DUF2642) 8 72 1.8E-24 T 29-03-2018 IPR020139 Protein of unknown function DUF2642 CXR48_RS14815 54cd04bdb3d36e92ef82372a5d93d745 78 ProDom PD058323 YUZF BH2251 3 72 1.0E-21 T 29-03-2018 IPR020139 Protein of unknown function DUF2642 CXR48_RS13855 6127267fb7b4ada8062f1b7e78f201b2 105 Pfam PF03413 Peptidase propeptide and YPEB domain 29 98 1.9E-7 T 29-03-2018 IPR025711 PepSY domain CXR48_RS12950 df3f32b8a53e8de3180a6cdc4bf98c31 340 TIGRFAM TIGR02904 spore_ysxE: spore coat protein YsxE 4 310 2.0E-104 T 29-03-2018 IPR014253 Spore coat protein YsxE CXR48_RS12950 df3f32b8a53e8de3180a6cdc4bf98c31 340 Gene3D G3DSA:3.90.1200.10 92 324 2.2E-16 T 29-03-2018 CXR48_RS12950 df3f32b8a53e8de3180a6cdc4bf98c31 340 Gene3D G3DSA:3.30.200.20 1 91 5.1E-8 T 29-03-2018 CXR48_RS12950 df3f32b8a53e8de3180a6cdc4bf98c31 340 SUPERFAMILY SSF56112 2 313 2.04E-14 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 Gene3D G3DSA:3.30.1490.100 243 360 2.4E-27 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 Hamap MF_01113 DNA polymerase IV [dinB]. 1 358 32.93 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 Pfam PF11798 IMS family HHH motif 172 201 3.4E-6 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 Pfam PF00817 impB/mucB/samB family 7 155 7.1E-44 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 Pfam PF11799 impB/mucB/samB family C-terminal domain 243 349 3.2E-20 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 SUPERFAMILY SSF56672 4 238 2.13E-73 T 29-03-2018 CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 Gene3D G3DSA:3.30.70.270 115 173 5.8E-9 T 29-03-2018 CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 Gene3D G3DSA:3.30.70.270 42 114 2.1E-20 T 29-03-2018 CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 SUPERFAMILY SSF100879 246 346 4.51E-21 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CXR48_RS11260 e9ad8218f37612d03487b6af672d9d43 408 Gene3D G3DSA:1.10.150.20 174 239 2.6E-20 T 29-03-2018 CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 5 267 2.4E-95 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 Gene3D G3DSA:3.40.50.720 1 125 4.6E-31 T 29-03-2018 CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 6 267 30.611 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 151 168 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 129 8.1E-32 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 Gene3D G3DSA:3.30.360.10 131 235 3.1E-36 T 29-03-2018 CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 SUPERFAMILY SSF55347 130 238 2.62E-37 T 29-03-2018 CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 SUPERFAMILY SSF51735 4 156 1.12E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 132 265 7.0E-33 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS10655 bb010414bb27f6c884e83313c8516599 267 PIRSF PIRSF000161 4 267 5.6E-71 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS09815 98a7b84abd67afc9795fa47d1eec6776 48 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 24 47 5.2E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS09815 98a7b84abd67afc9795fa47d1eec6776 48 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 22 47 6.6E-13 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 SUPERFAMILY SSF53850 90 292 2.17E-46 T 29-03-2018 CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.3E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 Gene3D G3DSA:3.40.190.10 88 176 4.9E-22 T 29-03-2018 CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.7E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.7E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.7E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 SUPERFAMILY SSF46785 1 111 5.92E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 Pfam PF03466 LysR substrate binding domain 90 290 5.1E-50 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 Gene3D G3DSA:1.10.10.10 1 83 7.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18155 79ff319c9cf93997ed03272dd69002a9 302 Gene3D G3DSA:3.40.190.10 177 264 4.5E-24 T 29-03-2018 CXR48_RS02075 feceb820d50916af409c86c008fcec99 131 Gene3D G3DSA:3.10.129.10 1 129 2.6E-27 T 29-03-2018 CXR48_RS02075 feceb820d50916af409c86c008fcec99 131 SUPERFAMILY SSF54637 4 128 3.57E-28 T 29-03-2018 IPR029069 HotDog domain CXR48_RS02075 feceb820d50916af409c86c008fcec99 131 Pfam PF07977 FabA-like domain 6 123 1.3E-9 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CXR48_RS09035 1219bd466f803b3059b85a355f4fb546 333 Gene3D G3DSA:3.40.50.2300 176 311 1.2E-30 T 29-03-2018 CXR48_RS09035 1219bd466f803b3059b85a355f4fb546 333 Gene3D G3DSA:1.10.260.40 4 57 2.0E-19 T 29-03-2018 CXR48_RS09035 1219bd466f803b3059b85a355f4fb546 333 Pfam PF13377 Periplasmic binding protein-like domain 171 332 8.4E-30 T 29-03-2018 CXR48_RS09035 1219bd466f803b3059b85a355f4fb546 333 SUPERFAMILY SSF47413 2 62 9.93E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS09035 1219bd466f803b3059b85a355f4fb546 333 SMART SM00354 3 74 1.9E-32 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS09035 1219bd466f803b3059b85a355f4fb546 333 SUPERFAMILY SSF53822 62 319 1.45E-64 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS09035 1219bd466f803b3059b85a355f4fb546 333 Gene3D G3DSA:3.40.50.2300 58 175 1.8E-34 T 29-03-2018 CXR48_RS09035 1219bd466f803b3059b85a355f4fb546 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 9.2E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS09035 1219bd466f803b3059b85a355f4fb546 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 29-03-2018 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 TIGRFAM TIGR01481 ccpA: catabolite control protein A 3 333 8.3E-161 T 29-03-2018 IPR006377 Catabolite control protein A GO:0006355 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 SUPERFAMILY SSF53822 63 333 1.26E-87 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 SMART SM00354 3 73 5.6E-39 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 Gene3D G3DSA:3.40.50.2300 177 321 3.9E-42 T 29-03-2018 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 SUPERFAMILY SSF47413 3 61 1.0E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 Gene3D G3DSA:3.40.50.2300 57 176 2.8E-36 T 29-03-2018 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 Pfam PF13377 Periplasmic binding protein-like domain 172 332 1.4E-34 T 29-03-2018 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 2.9E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 4.4E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 4.4E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 Gene3D G3DSA:1.10.260.40 4 56 1.3E-25 T 29-03-2018 CXR48_RS13795 97a6e1d46e7a156b3f979a0f20d055d8 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 29-03-2018 CXR48_RS00795 5f89d0b245e554bc1149ad87a61ca0c9 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.85 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00795 5f89d0b245e554bc1149ad87a61ca0c9 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.5E-42 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00795 5f89d0b245e554bc1149ad87a61ca0c9 179 Pfam PF00281 Ribosomal protein L5 24 80 2.9E-28 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00795 5f89d0b245e554bc1149ad87a61ca0c9 179 SUPERFAMILY SSF55282 3 178 1.3E-79 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00795 5f89d0b245e554bc1149ad87a61ca0c9 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00795 5f89d0b245e554bc1149ad87a61ca0c9 179 Gene3D G3DSA:3.30.1440.10 1 179 3.7E-82 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00795 5f89d0b245e554bc1149ad87a61ca0c9 179 PIRSF PIRSF002161 1 179 3.6E-70 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS03485 14c7ed58daeceedb12f6a964e13660c7 289 SUPERFAMILY SSF81301 2 132 2.65E-49 T 29-03-2018 CXR48_RS03485 14c7ed58daeceedb12f6a964e13660c7 289 Gene3D G3DSA:1.20.120.330 152 281 8.0E-47 T 29-03-2018 CXR48_RS03485 14c7ed58daeceedb12f6a964e13660c7 289 PIRSF PIRSF000812 1 284 1.6E-117 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase CXR48_RS03485 14c7ed58daeceedb12f6a964e13660c7 289 Pfam PF04439 Streptomycin adenylyltransferase 2 277 2.2E-114 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase CXR48_RS03485 14c7ed58daeceedb12f6a964e13660c7 289 SUPERFAMILY SSF81631 138 280 2.51E-51 T 29-03-2018 CXR48_RS03485 14c7ed58daeceedb12f6a964e13660c7 289 Gene3D G3DSA:3.30.460.10 9 151 6.2E-44 T 29-03-2018 CXR48_RS01805 b78dda935ac86b5dd47ee1d5f86da126 436 Gene3D G3DSA:3.90.1150.10 16 95 0.017 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS01805 b78dda935ac86b5dd47ee1d5f86da126 436 Gene3D G3DSA:3.90.1150.10 310 430 1.2E-8 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS01805 b78dda935ac86b5dd47ee1d5f86da126 436 SUPERFAMILY SSF53383 22 419 9.32E-59 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS01805 b78dda935ac86b5dd47ee1d5f86da126 436 Pfam PF00155 Aminotransferase class I and II 75 421 7.7E-28 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS01805 b78dda935ac86b5dd47ee1d5f86da126 436 Gene3D G3DSA:3.40.640.10 96 309 1.8E-22 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS04800 78e2aefcf452902a1f7961673fc80b3b 282 SUPERFAMILY SSF88713 80 275 1.53E-48 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CXR48_RS04800 78e2aefcf452902a1f7961673fc80b3b 282 Gene3D G3DSA:3.20.20.370 60 274 2.5E-45 T 29-03-2018 CXR48_RS04800 78e2aefcf452902a1f7961673fc80b3b 282 Pfam PF01522 Polysaccharide deacetylase 81 203 7.2E-28 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CXR48_RS06515 0906181ccd2fa51a4bb8051dc5fb59aa 141 SUPERFAMILY SSF82784 5 137 7.07E-34 T 29-03-2018 IPR003718 OsmC/Ohr family CXR48_RS06515 0906181ccd2fa51a4bb8051dc5fb59aa 141 Gene3D G3DSA:2.20.25.10 1 39 3.3E-12 T 29-03-2018 CXR48_RS06515 0906181ccd2fa51a4bb8051dc5fb59aa 141 Pfam PF02566 OsmC-like protein 44 137 1.5E-18 T 29-03-2018 IPR003718 OsmC/Ohr family CXR48_RS06515 0906181ccd2fa51a4bb8051dc5fb59aa 141 Gene3D G3DSA:3.30.300.20 47 141 5.3E-23 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS06515 0906181ccd2fa51a4bb8051dc5fb59aa 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 137 2.3E-49 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 Pfam PF00557 Metallopeptidase family M24 13 239 4.5E-57 T 29-03-2018 IPR000994 Peptidase M24 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 Gene3D G3DSA:3.90.230.10 1 248 4.2E-85 T 29-03-2018 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 43.399 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 2.0E-24 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 2.0E-24 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 2.0E-24 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 2.0E-24 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 SUPERFAMILY SSF55920 1 247 1.57E-90 T 29-03-2018 IPR000994 Peptidase M24 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.2E-104 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS00845 5b3b8feae79d105909cbe566c42846f9 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS13025 ed213c86621e354b70433b645fc80987 199 SUPERFAMILY SSF52016 1 196 1.08E-57 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CXR48_RS13025 ed213c86621e354b70433b645fc80987 199 Gene3D G3DSA:3.20.19.10 1 174 6.9E-47 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CXR48_RS13025 ed213c86621e354b70433b645fc80987 199 Pfam PF00694 Aconitase C-terminal domain 1 122 2.3E-33 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CXR48_RS13025 ed213c86621e354b70433b645fc80987 199 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 197 42.144 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CXR48_RS13025 ed213c86621e354b70433b645fc80987 199 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 186 8.4E-97 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CXR48_RS06565 a724d01684a1280ac42ebefa5e271bcc 319 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 46 57 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CXR48_RS06565 a724d01684a1280ac42ebefa5e271bcc 319 Pfam PF00082 Subtilase family 41 284 9.6E-61 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS06565 a724d01684a1280ac42ebefa5e271bcc 319 SUPERFAMILY SSF52743 22 294 7.72E-87 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS06565 a724d01684a1280ac42ebefa5e271bcc 319 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 244 254 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CXR48_RS06565 a724d01684a1280ac42ebefa5e271bcc 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 243 259 7.1E-22 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS06565 a724d01684a1280ac42ebefa5e271bcc 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 41 60 7.1E-22 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS06565 a724d01684a1280ac42ebefa5e271bcc 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 83 96 7.1E-22 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS06565 a724d01684a1280ac42ebefa5e271bcc 319 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 87 97 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CXR48_RS06565 a724d01684a1280ac42ebefa5e271bcc 319 Gene3D G3DSA:3.40.50.200 4 308 5.9E-91 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS13100 4f9a09080584cfe08cfcce8fa0ada5ab 272 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS13100 4f9a09080584cfe08cfcce8fa0ada5ab 272 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS13100 4f9a09080584cfe08cfcce8fa0ada5ab 272 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 216 1.3E-39 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS13100 4f9a09080584cfe08cfcce8fa0ada5ab 272 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 255 7.4E-102 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS13100 4f9a09080584cfe08cfcce8fa0ada5ab 272 Gene3D G3DSA:3.40.50.1860 119 272 1.8E-46 T 29-03-2018 CXR48_RS13100 4f9a09080584cfe08cfcce8fa0ada5ab 272 Hamap MF_00258 Glutamate racemase [murI]. 4 257 40.899 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS13100 4f9a09080584cfe08cfcce8fa0ada5ab 272 SUPERFAMILY SSF53681 5 108 1.44E-36 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS13100 4f9a09080584cfe08cfcce8fa0ada5ab 272 SUPERFAMILY SSF53681 110 264 1.05E-37 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS13100 4f9a09080584cfe08cfcce8fa0ada5ab 272 Gene3D G3DSA:3.40.50.1860 2 118 2.8E-28 T 29-03-2018 CXR48_RS06725 307d9052e5acb02f390dd5a545021890 259 Pfam PF00795 Carbon-nitrogen hydrolase 5 245 7.8E-48 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CXR48_RS06725 307d9052e5acb02f390dd5a545021890 259 SUPERFAMILY SSF56317 3 259 9.81E-74 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CXR48_RS06725 307d9052e5acb02f390dd5a545021890 259 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 141 161 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CXR48_RS06725 307d9052e5acb02f390dd5a545021890 259 Gene3D G3DSA:3.60.110.10 1 259 2.6E-77 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 Pfam PF07732 Multicopper oxidase 101 178 9.9E-6 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 Pfam PF07732 Multicopper oxidase 45 82 8.5E-6 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 Gene3D G3DSA:2.60.40.420 1 175 2.4E-35 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 SUPERFAMILY SSF49503 367 509 2.58E-33 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 Pfam PF07731 Multicopper oxidase 374 511 8.1E-24 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 Gene3D G3DSA:2.60.40.420 357 512 5.3E-35 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 Gene3D G3DSA:2.60.40.420 176 356 8.5E-40 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 Pfam PF00394 Multicopper oxidase 244 321 9.9E-7 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 SUPERFAMILY SSF49503 3 179 1.24E-35 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS03200 e09afc2b62628518f6f04782745ee8fe 512 SUPERFAMILY SSF49503 183 308 1.13E-27 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS03495 ba71a2b7bd39b0108113bf43e51daefb 87 PIRSF PIRSF010606 1 87 9.1E-40 T 29-03-2018 IPR016571 Spore coat assembly protein CotJB CXR48_RS03495 ba71a2b7bd39b0108113bf43e51daefb 87 Pfam PF12652 CotJB protein 11 86 5.0E-28 T 29-03-2018 IPR024207 Spore coat assembly protein CotJB, domain CXR48_RS11145 dcdcf33d011d976faaf1cbeea5bcad97 394 Gene3D G3DSA:3.30.70.1250 102 219 8.3E-57 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CXR48_RS11145 dcdcf33d011d976faaf1cbeea5bcad97 394 Pfam PF01676 Metalloenzyme superfamily 8 382 6.5E-47 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CXR48_RS11145 dcdcf33d011d976faaf1cbeea5bcad97 394 SUPERFAMILY SSF53649 220 393 5.5E-79 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CXR48_RS11145 dcdcf33d011d976faaf1cbeea5bcad97 394 SUPERFAMILY SSF53649 5 103 5.5E-79 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CXR48_RS11145 dcdcf33d011d976faaf1cbeea5bcad97 394 Gene3D G3DSA:3.40.720.10 259 394 7.9E-11 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CXR48_RS11145 dcdcf33d011d976faaf1cbeea5bcad97 394 PIRSF PIRSF001491 5 394 1.3E-167 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CXR48_RS11145 dcdcf33d011d976faaf1cbeea5bcad97 394 SUPERFAMILY SSF143856 103 219 5.49E-51 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CXR48_RS11145 dcdcf33d011d976faaf1cbeea5bcad97 394 Hamap MF_00740 Phosphopentomutase [deoB]. 6 390 55.446 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CXR48_RS11145 dcdcf33d011d976faaf1cbeea5bcad97 394 TIGRFAM TIGR01696 deoB: phosphopentomutase 8 388 2.9E-217 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CXR48_RS19300 12462a46a9bf528de8503da7f963b251 53 Pfam PF03190 Protein of unknown function, DUF255 8 52 1.3E-20 T 29-03-2018 IPR004879 Domain of unknown function DUF255 CXR48_RS19300 12462a46a9bf528de8503da7f963b251 53 Gene3D G3DSA:3.40.30.10 5 52 1.2E-8 T 29-03-2018 CXR48_RS19300 12462a46a9bf528de8503da7f963b251 53 SUPERFAMILY SSF52833 5 52 1.23E-11 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS10185 b0b28d55f237a3109c31cf2baed160e3 188 SUPERFAMILY SSF52499 4 182 6.02E-47 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS10185 b0b28d55f237a3109c31cf2baed160e3 188 Gene3D G3DSA:3.40.50.850 1 188 7.4E-46 T 29-03-2018 CXR48_RS10185 b0b28d55f237a3109c31cf2baed160e3 188 Pfam PF00857 Isochorismatase family 7 179 8.6E-32 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS09220 b1489b92d4e01ab856329e0eebc591f9 512 Gene3D G3DSA:3.20.20.80 40 356 1.1E-45 T 29-03-2018 CXR48_RS09220 b1489b92d4e01ab856329e0eebc591f9 512 Pfam PF02638 Glycosyl hydrolase-like 10 37 358 1.3E-121 T 29-03-2018 IPR003790 Glycosyl hydrolase-like 10 CXR48_RS09220 b1489b92d4e01ab856329e0eebc591f9 512 SUPERFAMILY SSF51445 67 328 1.08E-24 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS05660 8cf254f1af2d780a8ea2b5b4c4891bdc 395 PIRSF PIRSF007487 1 384 1.1E-83 T 29-03-2018 IPR021176 Competence-induced protein CoiA CXR48_RS05660 8cf254f1af2d780a8ea2b5b4c4891bdc 395 Pfam PF06054 Competence protein CoiA-like family 1 362 2.0E-65 T 29-03-2018 IPR010330 Competence-induced protein CoiA-like CXR48_RS15400 b56cedd8727f9a02413ab653d9d109e5 346 Gene3D G3DSA:3.40.50.720 1 176 8.1E-24 T 29-03-2018 CXR48_RS15400 b56cedd8727f9a02413ab653d9d109e5 346 Gene3D G3DSA:1.10.1040.10 180 333 2.2E-29 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS15400 b56cedd8727f9a02413ab653d9d109e5 346 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 140 6.3E-26 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CXR48_RS15400 b56cedd8727f9a02413ab653d9d109e5 346 SUPERFAMILY SSF48179 180 321 1.26E-22 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS15400 b56cedd8727f9a02413ab653d9d109e5 346 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 181 318 2.6E-25 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CXR48_RS15400 b56cedd8727f9a02413ab653d9d109e5 346 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 323 1.9E-51 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CXR48_RS15400 b56cedd8727f9a02413ab653d9d109e5 346 SUPERFAMILY SSF51735 1 173 5.34E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 161 1.5E-55 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 39.616 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 PIRSF PIRSF000114 1 333 7.8E-115 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 SUPERFAMILY SSF51735 3 179 5.65E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 1.1E-55 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 Gene3D G3DSA:3.40.50.720 1 179 8.8E-44 T 29-03-2018 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 Gene3D G3DSA:1.10.1040.10 181 331 1.1E-56 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS10830 7fe6dce1f03f21ac174ce126a6eee205 345 SUPERFAMILY SSF48179 181 332 7.31E-58 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS15780 85051bfd752b4e3222d8f569d135bdb7 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 227 1.9E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15780 85051bfd752b4e3222d8f569d135bdb7 235 SUPERFAMILY SSF161098 13 213 2.62E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15780 85051bfd752b4e3222d8f569d135bdb7 235 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 122 7.3E-13 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CXR48_RS15780 85051bfd752b4e3222d8f569d135bdb7 235 Gene3D G3DSA:1.10.3720.10 6 233 6.7E-27 T 29-03-2018 CXR48_RS03590 6eba743e20e73374673b9b225ea3d786 386 SUPERFAMILY SSF53448 2 142 9.5E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS03590 6eba743e20e73374673b9b225ea3d786 386 SUPERFAMILY SSF53448 194 262 9.5E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS03590 6eba743e20e73374673b9b225ea3d786 386 Pfam PF00535 Glycosyl transferase family 2 4 129 2.4E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS03590 6eba743e20e73374673b9b225ea3d786 386 Gene3D G3DSA:3.90.550.10 1 288 1.6E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 Pfam PF00067 Cytochrome P450 22 368 8.4E-32 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 Gene3D G3DSA:1.10.630.10 3 397 1.3E-77 T 29-03-2018 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 SUPERFAMILY SSF48264 12 397 3.93E-92 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 PRINTS PR00359 B-class P450 signature 196 218 1.1E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 PRINTS PR00359 B-class P450 signature 90 101 1.1E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 PRINTS PR00359 B-class P450 signature 318 333 1.1E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 PRINTS PR00359 B-class P450 signature 136 152 1.1E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 PRINTS PR00359 B-class P450 signature 153 168 1.1E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 PRINTS PR00359 B-class P450 signature 290 317 1.1E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 PRINTS PR00359 B-class P450 signature 348 359 1.1E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 PRINTS PR00359 B-class P450 signature 273 284 1.1E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS09140 abf6d34dfda3c229ef480d53428f461d 398 PRINTS PR00359 B-class P450 signature 339 348 1.1E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS16330 e43def70e6b17514594c80b8b3a865a9 106 Gene3D G3DSA:1.10.287.1080 1 106 1.8E-18 T 29-03-2018 CXR48_RS16330 e43def70e6b17514594c80b8b3a865a9 106 SUPERFAMILY SSF101386 1 104 5.56E-25 T 29-03-2018 CXR48_RS16330 e43def70e6b17514594c80b8b3a865a9 106 PIRSF PIRSF036521 1 106 5.0E-53 T 29-03-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related CXR48_RS16330 e43def70e6b17514594c80b8b3a865a9 106 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 102 4.3E-12 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CXR48_RS02640 39d7805a0d442b118e00ffe30cbfb274 321 Pfam PF01734 Patatin-like phospholipase 8 178 1.6E-13 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CXR48_RS02640 39d7805a0d442b118e00ffe30cbfb274 321 SUPERFAMILY SSF52151 4 301 6.28E-24 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS02640 39d7805a0d442b118e00ffe30cbfb274 321 Gene3D G3DSA:3.40.1090.10 2 316 1.1E-30 T 29-03-2018 CXR48_RS03215 8c48439a2e56bd70ab9f502a94934809 389 Gene3D G3DSA:3.40.50.410 210 352 5.9E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS03215 8c48439a2e56bd70ab9f502a94934809 389 Pfam PF01882 Protein of unknown function DUF58 202 275 1.4E-18 T 29-03-2018 IPR002881 Domain of unknown function DUF58 CXR48_RS06530 97aa343b97db92d27ccf6dcd5ebaca82 112 Gene3D G3DSA:2.160.20.50 1 70 9.4E-6 T 29-03-2018 CXR48_RS06530 97aa343b97db92d27ccf6dcd5ebaca82 112 Pfam PF01391 Collagen triple helix repeat (20 copies) 6 59 4.7E-9 T 29-03-2018 IPR008160 Collagen triple helix repeat CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 Pfam PF00667 FAD binding domain 663 871 2.6E-43 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 SUPERFAMILY SSF52343 891 1050 3.01E-44 T 29-03-2018 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 Pfam PF00258 Flavodoxin 488 620 9.2E-27 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 Pfam PF00175 Oxidoreductase NAD-binding domain 904 1014 1.4E-16 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 Gene3D G3DSA:2.40.30.10 649 883 1.4E-51 T 29-03-2018 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 SUPERFAMILY SSF48264 4 453 2.36E-104 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PIRSF PIRSF000209 1 1053 0.0 T 29-03-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 SUPERFAMILY SSF52218 483 635 1.11E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 Pfam PF00067 Cytochrome P450 17 449 1.0E-82 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00369 Flavodoxin signature 487 500 7.0E-13 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00369 Flavodoxin signature 534 545 7.0E-13 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00369 Flavodoxin signature 565 575 7.0E-13 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00369 Flavodoxin signature 590 609 7.0E-13 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 396 405 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 Gene3D G3DSA:1.10.630.10 3 459 3.3E-110 T 29-03-2018 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 Gene3D G3DSA:3.40.50.80 889 1049 7.5E-33 T 29-03-2018 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 SUPERFAMILY SSF63380 662 888 1.04E-67 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 Gene3D G3DSA:3.40.50.360 460 647 7.9E-41 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 831 838 9.0E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 945 956 9.0E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 698 708 9.0E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 903 922 9.0E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 932 941 9.0E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 976 992 9.0E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 866 875 9.0E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS12485 c7215b1855a644f8addfc15958a64468 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 999 1007 9.0E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CXR48_RS18670 8037995fff3a2bc9ffae34bf08dcf525 257 Pfam PF00005 ABC transporter 23 171 3.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS18670 8037995fff3a2bc9ffae34bf08dcf525 257 Gene3D G3DSA:3.40.50.300 1 240 5.0E-63 T 29-03-2018 CXR48_RS18670 8037995fff3a2bc9ffae34bf08dcf525 257 SMART SM00382 32 220 3.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS18670 8037995fff3a2bc9ffae34bf08dcf525 257 SUPERFAMILY SSF52540 4 224 2.1E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS18670 8037995fff3a2bc9ffae34bf08dcf525 257 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 Gene3D G3DSA:3.40.640.10 174 297 3.8E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 PIRSF PIRSF000521 177 401 1.1E-31 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 PIRSF PIRSF000521 3 162 1.6E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 Gene3D G3DSA:3.90.1150.10 2 167 1.6E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 Hamap MF_01689 Ornithine aminotransferase [rocD]. 7 399 65.543 T 29-03-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 Pfam PF00202 Aminotransferase class-III 18 398 8.2E-136 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 15 399 36.857 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 7 398 1.5E-162 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 Gene3D G3DSA:3.90.1150.10 298 401 1.1E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 226 263 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CXR48_RS18950 ae48487e5fcdbc6550aae11fd0bcae32 401 SUPERFAMILY SSF53383 5 399 5.56E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS16805 01c9f821f1d1b26657c4220d082d24d7 294 Gene3D G3DSA:3.90.550.10 1 277 6.8E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16805 01c9f821f1d1b26657c4220d082d24d7 294 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 2.6E-123 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CXR48_RS16805 01c9f821f1d1b26657c4220d082d24d7 294 SUPERFAMILY SSF53448 4 274 6.88E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16805 01c9f821f1d1b26657c4220d082d24d7 294 Pfam PF00483 Nucleotidyl transferase 6 264 2.9E-34 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CXR48_RS12275 f75a136c4adaf017951e799834734223 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 88 3.0E-32 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS12275 f75a136c4adaf017951e799834734223 88 SUPERFAMILY SSF46992 3 86 3.01E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS12275 f75a136c4adaf017951e799834734223 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.128 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS12275 f75a136c4adaf017951e799834734223 88 Gene3D G3DSA:1.20.58.110 1 88 1.5E-29 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS12275 f75a136c4adaf017951e799834734223 88 Pfam PF01649 Ribosomal protein S20 2 84 6.1E-27 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS12275 f75a136c4adaf017951e799834734223 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 1.1E-33 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS04090 90aa3877a486409cc119e46d78c3d612 194 PIRSF PIRSF000232 8 194 4.6E-47 T 29-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like CXR48_RS04090 90aa3877a486409cc119e46d78c3d612 194 Gene3D G3DSA:3.40.109.10 4 193 2.8E-34 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS04090 90aa3877a486409cc119e46d78c3d612 194 Pfam PF00881 Nitroreductase family 17 174 4.5E-25 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CXR48_RS04090 90aa3877a486409cc119e46d78c3d612 194 SUPERFAMILY SSF55469 11 192 2.49E-37 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS03345 cbeb6122d4969f83a4896e593a6ce1b5 524 Gene3D G3DSA:3.20.20.70 104 522 2.5E-88 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS03345 cbeb6122d4969f83a4896e593a6ce1b5 524 PIRSF PIRSF006429 1 524 9.8E-165 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein CXR48_RS03345 cbeb6122d4969f83a4896e593a6ce1b5 524 PIRSF PIRSF500060 1 524 1.3E-216 T 29-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria CXR48_RS03345 cbeb6122d4969f83a4896e593a6ce1b5 524 SUPERFAMILY SSF51395 7 124 1.34E-106 T 29-03-2018 CXR48_RS03345 cbeb6122d4969f83a4896e593a6ce1b5 524 SUPERFAMILY SSF51395 163 518 1.34E-106 T 29-03-2018 CXR48_RS03345 cbeb6122d4969f83a4896e593a6ce1b5 524 Pfam PF01645 Conserved region in glutamate synthase 116 493 1.1E-117 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CXR48_RS18030 a067563faebfe3d729ceeb2d54594dd2 249 SUPERFAMILY SSF55469 1 247 1.96E-72 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS18030 a067563faebfe3d729ceeb2d54594dd2 249 Pfam PF00881 Nitroreductase family 8 165 3.9E-20 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CXR48_RS18030 a067563faebfe3d729ceeb2d54594dd2 249 Gene3D G3DSA:3.40.109.10 1 249 3.2E-59 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS18030 a067563faebfe3d729ceeb2d54594dd2 249 PIRSF PIRSF005426 1 249 5.7E-95 T 29-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 CXR48_RS10460 c1f64956a76c72e99f3718f5eefa5992 434 Pfam PF00860 Permease family 7 385 5.8E-123 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS10460 c1f64956a76c72e99f3718f5eefa5992 434 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 332 352 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CXR48_RS10460 c1f64956a76c72e99f3718f5eefa5992 434 TIGRFAM TIGR03173 pbuX: xanthine permease 11 417 7.8E-166 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CXR48_RS10460 c1f64956a76c72e99f3718f5eefa5992 434 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 6 415 4.2E-146 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CXR48_RS07290 3da254509db0b6bcba2eb79ed075df5c 263 Pfam PF01522 Polysaccharide deacetylase 71 191 3.0E-25 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CXR48_RS07290 3da254509db0b6bcba2eb79ed075df5c 263 Gene3D G3DSA:3.20.20.370 28 262 1.9E-44 T 29-03-2018 CXR48_RS07290 3da254509db0b6bcba2eb79ed075df5c 263 SUPERFAMILY SSF88713 58 258 1.26E-40 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CXR48_RS19280 eb52844efdaf0e63b8ba3bf80ba1722a 69 SUPERFAMILY SSF52833 5 67 5.37E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS19280 eb52844efdaf0e63b8ba3bf80ba1722a 69 Pfam PF03190 Protein of unknown function, DUF255 8 67 7.7E-26 T 29-03-2018 IPR004879 Domain of unknown function DUF255 CXR48_RS19280 eb52844efdaf0e63b8ba3bf80ba1722a 69 Gene3D G3DSA:3.40.30.10 5 68 3.0E-12 T 29-03-2018 CXR48_RS10745 bae03c7896c0b107d955cd26ed2fa887 250 Gene3D G3DSA:3.20.20.70 2 250 9.2E-63 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS10745 bae03c7896c0b107d955cd26ed2fa887 250 SUPERFAMILY SSF51366 17 249 8.36E-76 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CXR48_RS10745 bae03c7896c0b107d955cd26ed2fa887 250 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 249 31.27 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CXR48_RS10745 bae03c7896c0b107d955cd26ed2fa887 250 Pfam PF00218 Indole-3-glycerol phosphate synthase 21 246 4.6E-84 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CXR48_RS10745 bae03c7896c0b107d955cd26ed2fa887 250 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 42 60 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CXR48_RS01035 1d9644c035640d0c7e0a4b38d28c655f 427 Gene3D G3DSA:3.40.710.10 17 427 6.4E-83 T 29-03-2018 CXR48_RS01035 1d9644c035640d0c7e0a4b38d28c655f 427 Pfam PF00144 Beta-lactamase 38 406 2.5E-72 T 29-03-2018 IPR001466 Beta-lactamase-related CXR48_RS01035 1d9644c035640d0c7e0a4b38d28c655f 427 SUPERFAMILY SSF56601 33 394 4.47E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS01035 1d9644c035640d0c7e0a4b38d28c655f 427 Hamap MF_01034 UPF0214 protein YfeW [yfeW]. 1 427 70.405 T 29-03-2018 IPR022849 Peptidase S12, UPF0214, YfeW-type CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 Gene3D G3DSA:3.20.20.80 45 388 3.9E-59 T 29-03-2018 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 SMART SM00642 50 383 2.9E-17 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 SUPERFAMILY SSF51445 47 354 1.22E-58 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 Gene3D G3DSA:2.60.40.10 552 654 1.8E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 Gene3D G3DSA:2.60.40.1180 389 466 6.8E-21 T 29-03-2018 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 SUPERFAMILY SSF51011 392 465 1.15E-16 T 29-03-2018 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 Pfam PF00128 Alpha amylase, catalytic domain 64 322 7.7E-16 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 SMART SM00632 393 468 8.2E-13 T 29-03-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 Pfam PF16738 Starch-binding module 26 566 637 7.5E-20 T 29-03-2018 IPR031965 Starch-binding module 26 KEGG: 00500+3.2.1.1 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 PRINTS PR00110 Alpha-amylase signature 99 116 1.5E-10 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 PRINTS PR00110 Alpha-amylase signature 132 143 1.5E-10 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 PRINTS PR00110 Alpha-amylase signature 211 222 1.5E-10 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CXR48_RS01610 4c2868a9633cf1265d2304fa15c69654 659 PRINTS PR00110 Alpha-amylase signature 300 312 1.5E-10 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CXR48_RS11425 7126db50c59cc5eb149b4776230fcca3 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS11425 7126db50c59cc5eb149b4776230fcca3 49 Pfam PF00471 Ribosomal protein L33 3 49 4.5E-22 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS11425 7126db50c59cc5eb149b4776230fcca3 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.101 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS11425 7126db50c59cc5eb149b4776230fcca3 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 7.7E-19 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS11425 7126db50c59cc5eb149b4776230fcca3 49 SUPERFAMILY SSF57829 1 49 2.2E-18 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CXR48_RS15325 0bb61e84c0a50b75710cca1fd377a0e0 78 ProDom PD058325 YUSG BH3483 7 78 5.0E-29 T 29-03-2018 IPR020140 Uncharacterised protein family YusG CXR48_RS15325 0bb61e84c0a50b75710cca1fd377a0e0 78 Pfam PF10830 Protein of unknown function (DUF2553) 6 78 9.1E-31 T 29-03-2018 IPR020140 Uncharacterised protein family YusG CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 Pfam PF12538 DNA transporter 3 121 4.9E-23 T 29-03-2018 IPR022206 Firmicutes EssC, N-terminal CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 206 1481 0.0 T 29-03-2018 IPR023839 Firmicutes EssC, C-terminal CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 SUPERFAMILY SSF52540 1239 1393 1.85E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 SUPERFAMILY SSF52540 639 897 6.5E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 Gene3D G3DSA:2.60.200.20 95 195 2.1E-8 T 29-03-2018 CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 SUPERFAMILY SSF52540 954 1168 3.36E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 Pfam PF01580 FtsK/SpoIIIE family 640 852 2.5E-29 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 Pfam PF01580 FtsK/SpoIIIE family 981 1159 1.1E-23 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 Pfam PF01580 FtsK/SpoIIIE family 1260 1374 2.4E-7 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 Gene3D G3DSA:3.40.50.300 922 1175 2.3E-9 T 29-03-2018 CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 Gene3D G3DSA:3.40.50.300 1206 1422 4.3E-6 T 29-03-2018 CXR48_RS14840 4f1e3824cfd7e516c646e22367b3d2dc 1491 Gene3D G3DSA:3.40.50.300 498 891 3.5E-26 T 29-03-2018 CXR48_RS10800 b3f4fed5488a8a29f642a33bb3f1cb18 75 SUPERFAMILY SSF51219 7 74 3.4E-36 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CXR48_RS10800 b3f4fed5488a8a29f642a33bb3f1cb18 75 Hamap MF_00798 Transcription attenuation protein MtrB [mtrB]. 1 73 29.735 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CXR48_RS10800 b3f4fed5488a8a29f642a33bb3f1cb18 75 Gene3D G3DSA:2.60.40.50 8 73 5.3E-39 T 29-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain CXR48_RS10800 b3f4fed5488a8a29f642a33bb3f1cb18 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 58 74 5.0E-40 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CXR48_RS10800 b3f4fed5488a8a29f642a33bb3f1cb18 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 42 58 5.0E-40 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CXR48_RS10800 b3f4fed5488a8a29f642a33bb3f1cb18 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 9 26 5.0E-40 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CXR48_RS10800 b3f4fed5488a8a29f642a33bb3f1cb18 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 26 42 5.0E-40 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CXR48_RS10800 b3f4fed5488a8a29f642a33bb3f1cb18 75 Pfam PF02081 Tryptophan RNA-binding attenuator protein 6 73 5.0E-40 T 29-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain CXR48_RS00465 a3b3de24a83591c03eeaef482b809117 120 Gene3D G3DSA:3.30.1130.10 1 119 3.1E-37 T 29-03-2018 CXR48_RS00465 a3b3de24a83591c03eeaef482b809117 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 7.2E-46 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CXR48_RS00465 a3b3de24a83591c03eeaef482b809117 120 Pfam PF02152 Dihydroneopterin aldolase 4 116 5.3E-36 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CXR48_RS00465 a3b3de24a83591c03eeaef482b809117 120 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 4.9E-41 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CXR48_RS00465 a3b3de24a83591c03eeaef482b809117 120 SMART SM00905 4 117 3.9E-53 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CXR48_RS00465 a3b3de24a83591c03eeaef482b809117 120 SUPERFAMILY SSF55620 2 119 5.34E-41 T 29-03-2018 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 7.8E-76 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 SUPERFAMILY SSF56053 1 83 1.57E-27 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 SUPERFAMILY SSF56053 84 177 3.17E-34 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 Pfam PF00347 Ribosomal protein L6 91 165 1.9E-20 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 Pfam PF00347 Ribosomal protein L6 11 83 5.9E-24 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 1.7E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 1.7E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 1.7E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 PIRSF PIRSF002162 1 178 1.3E-46 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 Gene3D G3DSA:3.90.930.12 84 179 3.1E-39 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 Gene3D G3DSA:3.90.930.12 2 83 1.8E-30 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00810 7df3d8e699bf8074bac19f277ea6e223 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 39.122 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CXR48_RS08030 08edab251b445163bcc1b7d46f36e4a3 299 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 284 8.4E-84 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CXR48_RS08030 08edab251b445163bcc1b7d46f36e4a3 299 Gene3D G3DSA:3.40.50.450 114 265 3.2E-34 T 29-03-2018 CXR48_RS08030 08edab251b445163bcc1b7d46f36e4a3 299 Pfam PF02481 DNA recombination-mediator protein A 73 278 8.3E-75 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CXR48_RS08030 08edab251b445163bcc1b7d46f36e4a3 299 SUPERFAMILY SSF102405 82 283 9.92E-39 T 29-03-2018 CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 SUPERFAMILY SSF56601 171 569 1.37E-100 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 201 3.5E-22 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 SUPERFAMILY SSF54184 584 637 5.76E-11 T 29-03-2018 CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 11 637 1.5E-265 T 29-03-2018 IPR011927 Stage V sporulation protein D CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 Pfam PF03793 PASTA domain 584 637 4.0E-14 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 SMART SM00740 580 638 2.5E-16 T 29-03-2018 IPR005543 PASTA domain CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 Gene3D G3DSA:3.90.1310.10 24 217 2.9E-45 T 29-03-2018 CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 Gene3D G3DSA:3.40.710.10 218 562 1.1E-95 T 29-03-2018 CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 SUPERFAMILY SSF56519 52 220 1.83E-43 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS07565 e46ed5635df2b64a7351cc686355c605 639 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 556 3.8E-87 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS08710 8ffa24016d513b2725ef3ff58775a28a 134 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS08710 8ffa24016d513b2725ef3ff58775a28a 134 SUPERFAMILY SSF46955 12 83 5.04E-19 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS08710 8ffa24016d513b2725ef3ff58775a28a 134 Gene3D G3DSA:1.10.1660.10 1 119 1.7E-23 T 29-03-2018 CXR48_RS08710 8ffa24016d513b2725ef3ff58775a28a 134 SMART SM00422 12 80 1.2E-28 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS08710 8ffa24016d513b2725ef3ff58775a28a 134 Pfam PF13411 MerR HTH family regulatory protein 13 79 1.7E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS06660 257d6a9148a294071063a56bf43b03b7 251 Pfam PF04542 Sigma-70 region 2 36 107 2.5E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS06660 257d6a9148a294071063a56bf43b03b7 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 229 2.4E-13 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS06660 257d6a9148a294071063a56bf43b03b7 251 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 22 245 1.1E-87 T 29-03-2018 IPR014244 RNA polymerase sigma-I type CXR48_RS06660 257d6a9148a294071063a56bf43b03b7 251 PIRSF PIRSF038953 7 251 1.1E-72 T 29-03-2018 IPR014244 RNA polymerase sigma-I type CXR48_RS06660 257d6a9148a294071063a56bf43b03b7 251 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 17 247 29.736 T 29-03-2018 IPR014244 RNA polymerase sigma-I type CXR48_RS06660 257d6a9148a294071063a56bf43b03b7 251 Gene3D G3DSA:1.10.1740.10 20 104 1.2E-15 T 29-03-2018 CXR48_RS06660 257d6a9148a294071063a56bf43b03b7 251 SUPERFAMILY SSF88946 23 104 2.98E-18 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS06690 602d2ed10d317c21da517f4e74f3f27c 224 Pfam PF04239 Protein of unknown function (DUF421) 84 170 7.7E-19 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CXR48_RS06690 602d2ed10d317c21da517f4e74f3f27c 224 Gene3D G3DSA:3.30.240.20 77 145 5.8E-17 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CXR48_RS17185 7b2541f08f9671b97f1200ab78013215 136 Pfam PF14183 YwpF-like protein 2 135 4.5E-45 T 29-03-2018 IPR025573 YwpF-like protein CXR48_RS16820 e84baee243c94b3214583925bef29524 724 SUPERFAMILY SSF53756 484 646 4.55E-10 T 29-03-2018 CXR48_RS16820 e84baee243c94b3214583925bef29524 724 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 351 721 8.0E-130 T 29-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CXR48_RS12605 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 SMART SM00732 1 103 8.6E-41 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CXR48_RS12605 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 138 27.916 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CXR48_RS12605 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 4.8E-60 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CXR48_RS12605 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 Pfam PF03652 Holliday junction resolvase 1 136 6.0E-45 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CXR48_RS12605 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 Gene3D G3DSA:3.30.420.140 1 138 7.3E-46 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CXR48_RS12605 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 SUPERFAMILY SSF53098 1 137 2.88E-45 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS02205 9ddbec656501d232d34e99b7d5502000 575 Gene3D G3DSA:3.20.20.370 216 507 1.6E-12 T 29-03-2018 CXR48_RS02205 9ddbec656501d232d34e99b7d5502000 575 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 215 480 6.6E-59 T 29-03-2018 IPR018763 Protein of unknown function DUF2334 CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 SMART SM00387 24 177 8.1E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 SUPERFAMILY SSF55874 3 209 5.37E-63 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 29-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 SUPERFAMILY SSF110942 511 625 3.01E-29 T 29-03-2018 CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 Pfam PF00183 Hsp90 protein 216 625 1.5E-111 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 Pfam PF00183 Hsp90 protein 184 229 1.4E-6 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 SUPERFAMILY SSF54211 236 488 1.52E-81 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 Gene3D G3DSA:3.30.565.10 26 220 3.6E-54 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 PRINTS PR00775 90kDa heat shock protein signature 2 22 4.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 PRINTS PR00775 90kDa heat shock protein signature 23 45 4.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 PRINTS PR00775 90kDa heat shock protein signature 165 182 4.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 PRINTS PR00775 90kDa heat shock protein signature 115 137 4.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 PRINTS PR00775 90kDa heat shock protein signature 188 206 4.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 PRINTS PR00775 90kDa heat shock protein signature 90 107 4.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 PRINTS PR00775 90kDa heat shock protein signature 72 89 4.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 PIRSF PIRSF002583 1 626 1.6E-205 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 Hamap MF_00505 Chaperone protein HtpG [htpG]. 2 626 27.251 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CXR48_RS18750 657aefe66a18d14d0b88c85cafbda351 626 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 150 9.4E-13 T 29-03-2018 CXR48_RS01375 0b0d5aa592d394c5e75ac9a9f1ba58aa 307 Gene3D G3DSA:3.30.200.20 8 93 0.001 T 29-03-2018 CXR48_RS01375 0b0d5aa592d394c5e75ac9a9f1ba58aa 307 SUPERFAMILY SSF56112 27 262 5.47E-32 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS01375 0b0d5aa592d394c5e75ac9a9f1ba58aa 307 Pfam PF01636 Phosphotransferase enzyme family 33 266 1.5E-25 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CXR48_RS01375 0b0d5aa592d394c5e75ac9a9f1ba58aa 307 Gene3D G3DSA:3.90.1200.10 124 298 4.6E-15 T 29-03-2018 CXR48_RS09690 ebbf5255274faf7eb41f239d12b3f6b9 496 Pfam PF00474 Sodium:solute symporter family 40 432 8.9E-21 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS05950 ae80c79e8248d704e3376ab3726c42b0 568 Gene3D G3DSA:3.40.50.2300 461 567 2.5E-16 T 29-03-2018 CXR48_RS05950 ae80c79e8248d704e3376ab3726c42b0 568 Pfam PF02378 Phosphotransferase system, EIIC 28 347 3.5E-57 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS05950 ae80c79e8248d704e3376ab3726c42b0 568 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 467 542 3.9E-12 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS05950 ae80c79e8248d704e3376ab3726c42b0 568 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 445 561 1.6E-33 T 29-03-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CXR48_RS05950 ae80c79e8248d704e3376ab3726c42b0 568 SUPERFAMILY SSF52794 466 565 1.6E-14 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS05950 ae80c79e8248d704e3376ab3726c42b0 568 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 420 4.1E-72 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CXR48_RS12340 7859f966135fb8bd18c78f47c5629ca4 366 Gene3D G3DSA:3.40.50.300 55 223 1.4E-33 T 29-03-2018 CXR48_RS12340 7859f966135fb8bd18c78f47c5629ca4 366 Pfam PF01926 50S ribosome-binding GTPase 162 224 2.9E-13 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS12340 7859f966135fb8bd18c78f47c5629ca4 366 SUPERFAMILY SSF52540 61 277 7.02E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12340 7859f966135fb8bd18c78f47c5629ca4 366 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 366 2.2E-163 T 29-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH CXR48_RS09595 bc65bf2a53b62b55d51fca6a27a650c5 196 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 51 187 1.1E-34 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CXR48_RS09595 bc65bf2a53b62b55d51fca6a27a650c5 196 Gene3D G3DSA:2.60.40.200 40 196 2.0E-37 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CXR48_RS09595 bc65bf2a53b62b55d51fca6a27a650c5 196 SUPERFAMILY SSF49329 45 188 1.44E-36 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CXR48_RS03170 5b3d53a2fda5eb02df37e0fc889caa6c 165 SUPERFAMILY SSF88659 101 159 1.76E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS03170 5b3d53a2fda5eb02df37e0fc889caa6c 165 Gene3D G3DSA:1.10.10.10 89 165 1.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03170 5b3d53a2fda5eb02df37e0fc889caa6c 165 SUPERFAMILY SSF88946 19 91 1.02E-14 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS03170 5b3d53a2fda5eb02df37e0fc889caa6c 165 Gene3D G3DSA:1.10.1740.10 2 82 1.3E-13 T 29-03-2018 CXR48_RS03170 5b3d53a2fda5eb02df37e0fc889caa6c 165 Pfam PF04542 Sigma-70 region 2 20 80 1.1E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS03170 5b3d53a2fda5eb02df37e0fc889caa6c 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 158 1.0E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS03170 5b3d53a2fda5eb02df37e0fc889caa6c 165 Pfam PF08281 Sigma-70, region 4 104 154 5.7E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS11890 97d26d676ffb8abd829f1f6afe60351e 433 SUPERFAMILY SSF54631 203 343 2.15E-26 T 29-03-2018 CXR48_RS11890 97d26d676ffb8abd829f1f6afe60351e 433 Pfam PF00571 CBS domain 223 272 0.0011 T 29-03-2018 IPR000644 CBS domain CXR48_RS11890 97d26d676ffb8abd829f1f6afe60351e 433 Pfam PF00571 CBS domain 293 340 0.0042 T 29-03-2018 IPR000644 CBS domain CXR48_RS11890 97d26d676ffb8abd829f1f6afe60351e 433 SMART SM01091 356 433 3.2E-18 T 29-03-2018 IPR005170 Transporter-associated domain CXR48_RS11890 97d26d676ffb8abd829f1f6afe60351e 433 Gene3D G3DSA:3.30.465.10 347 433 1.3E-18 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS11890 97d26d676ffb8abd829f1f6afe60351e 433 Gene3D G3DSA:3.10.580.10 195 346 1.3E-27 T 29-03-2018 CXR48_RS11890 97d26d676ffb8abd829f1f6afe60351e 433 Pfam PF01595 Domain of unknown function DUF21 9 201 9.7E-47 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CXR48_RS11890 97d26d676ffb8abd829f1f6afe60351e 433 Pfam PF03471 Transporter associated domain 357 431 2.4E-14 T 29-03-2018 IPR005170 Transporter-associated domain CXR48_RS11890 97d26d676ffb8abd829f1f6afe60351e 433 SUPERFAMILY SSF56176 351 428 6.54E-14 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 Pfam PF12833 Helix-turn-helix domain 105 183 2.7E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 SUPERFAMILY SSF57884 8 89 8.63E-32 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 136 178 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 PIRSF PIRSF000408 3 189 2.5E-81 T 29-03-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 Gene3D G3DSA:3.40.10.10 1 77 3.4E-23 T 29-03-2018 IPR035451 Ada-like domain CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 Gene3D G3DSA:1.10.10.60 80 133 1.5E-16 T 29-03-2018 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 Gene3D G3DSA:1.10.10.60 134 189 5.4E-14 T 29-03-2018 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 SUPERFAMILY SSF46689 83 133 3.23E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 Pfam PF02805 Metal binding domain of Ada 11 74 7.8E-30 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 151 166 1.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 166 182 1.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 SUPERFAMILY SSF46689 135 184 1.48E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS19340 d1cfeb4888fa98fbc3376c7c6aeb4ab7 193 SMART SM00342 99 182 1.5E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CXR48_RS11200 7a183f12bb5be552d418484ea886e41b 117 SUPERFAMILY SSF47413 4 66 9.92E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS11200 7a183f12bb5be552d418484ea886e41b 117 Pfam PF01381 Helix-turn-helix 8 60 1.1E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS11200 7a183f12bb5be552d418484ea886e41b 117 SMART SM00530 5 60 3.3E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS11200 7a183f12bb5be552d418484ea886e41b 117 Gene3D G3DSA:1.10.3100.10 1 117 3.5E-19 T 29-03-2018 IPR027910 YdiL-like domain CXR48_RS14595 a29bc3594e0bc03305c7eeb685a74445 390 Gene3D G3DSA:3.40.50.1970 9 183 3.6E-50 T 29-03-2018 CXR48_RS14595 a29bc3594e0bc03305c7eeb685a74445 390 Gene3D G3DSA:1.20.1090.10 184 390 7.5E-45 T 29-03-2018 CXR48_RS14595 a29bc3594e0bc03305c7eeb685a74445 390 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CXR48_RS14595 a29bc3594e0bc03305c7eeb685a74445 390 SUPERFAMILY SSF56796 1 388 7.2E-116 T 29-03-2018 CXR48_RS14595 a29bc3594e0bc03305c7eeb685a74445 390 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 367 1.5E-99 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CXR48_RS14595 a29bc3594e0bc03305c7eeb685a74445 390 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 Pfam PF00989 PAS fold 239 343 4.7E-14 T 29-03-2018 IPR013767 PAS fold GO:0006355 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 530 4.9E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 516 4.9E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 561 574 4.9E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 555 4.9E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 SMART SM00091 236 302 0.002 T 29-03-2018 IPR000014 PAS domain CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 SMART SM00387 465 577 2.8E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 235 352 1.3E-6 T 29-03-2018 IPR000014 PAS domain CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 SMART SM00388 352 419 6.6E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 SUPERFAMILY SSF55785 235 339 4.19E-10 T 29-03-2018 IPR000014 PAS domain CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 SUPERFAMILY SSF55874 408 575 4.32E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 Gene3D G3DSA:3.30.450.20 234 357 4.0E-17 T 29-03-2018 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 SUPERFAMILY SSF47384 338 420 1.73E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 Gene3D G3DSA:3.30.565.10 423 579 1.0E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 Pfam PF16736 Single Cache-like 36 141 1.1E-11 T 29-03-2018 IPR031967 PhoR, single Cache-like domain CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 465 575 1.9E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 Pfam PF00512 His Kinase A (phospho-acceptor) domain 352 418 3.7E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 Gene3D G3DSA:1.10.287.130 358 415 4.5E-20 T 29-03-2018 CXR48_RS13450 9e8f7a848ee426cc5d0a955dc3426fb3 579 Gene3D G3DSA:3.30.450.20 30 147 1.3E-7 T 29-03-2018 CXR48_RS06465 b181b4158acbdb616f773b9706ee5c04 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 298 6.7E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS06465 b181b4158acbdb616f773b9706ee5c04 323 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS06465 b181b4158acbdb616f773b9706ee5c04 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 318 3.0E-25 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS06465 b181b4158acbdb616f773b9706ee5c04 323 SUPERFAMILY SSF52540 35 315 6.03E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS06465 b181b4158acbdb616f773b9706ee5c04 323 SMART SM00382 36 229 4.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS06465 b181b4158acbdb616f773b9706ee5c04 323 Gene3D G3DSA:3.40.50.300 3 323 3.4E-85 T 29-03-2018 CXR48_RS06465 b181b4158acbdb616f773b9706ee5c04 323 Pfam PF00005 ABC transporter 28 179 2.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS01485 5a811fce6a299f3a1e0812d5f6f03960 310 PRINTS PR00069 Aldo-keto reductase signature 242 266 1.1E-14 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01485 5a811fce6a299f3a1e0812d5f6f03960 310 PRINTS PR00069 Aldo-keto reductase signature 142 159 1.1E-14 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01485 5a811fce6a299f3a1e0812d5f6f03960 310 PRINTS PR00069 Aldo-keto reductase signature 111 129 1.1E-14 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01485 5a811fce6a299f3a1e0812d5f6f03960 310 PRINTS PR00069 Aldo-keto reductase signature 45 69 1.1E-14 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01485 5a811fce6a299f3a1e0812d5f6f03960 310 SUPERFAMILY SSF51430 3 309 1.7E-95 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS01485 5a811fce6a299f3a1e0812d5f6f03960 310 Pfam PF00248 Aldo/keto reductase family 16 308 1.9E-74 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS01485 5a811fce6a299f3a1e0812d5f6f03960 310 Gene3D G3DSA:3.20.20.100 1 310 1.8E-94 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS17930 eddb4c57fa0d3b6ef8d914f2fd7debcf 389 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 381 1.1E-142 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CXR48_RS17930 eddb4c57fa0d3b6ef8d914f2fd7debcf 389 Gene3D G3DSA:3.40.640.10 17 250 1.5E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS17930 eddb4c57fa0d3b6ef8d914f2fd7debcf 389 SUPERFAMILY SSF53383 9 386 1.32E-125 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS17930 eddb4c57fa0d3b6ef8d914f2fd7debcf 389 PIRSF PIRSF000390 5 388 2.3E-121 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CXR48_RS17930 eddb4c57fa0d3b6ef8d914f2fd7debcf 389 Gene3D G3DSA:3.90.1150.10 251 389 3.8E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS19130 dc7c80bdd0861394e58fff67fb9e173b 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.576 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS19130 dc7c80bdd0861394e58fff67fb9e173b 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19130 dc7c80bdd0861394e58fff67fb9e173b 149 SUPERFAMILY SSF55658 1 56 6.8E-17 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CXR48_RS19130 dc7c80bdd0861394e58fff67fb9e173b 149 SUPERFAMILY SSF55653 56 148 4.45E-29 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CXR48_RS19130 dc7c80bdd0861394e58fff67fb9e173b 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 1.2E-53 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS19130 dc7c80bdd0861394e58fff67fb9e173b 149 Gene3D G3DSA:3.40.5.10 1 49 4.1E-22 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19130 dc7c80bdd0861394e58fff67fb9e173b 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 2.9E-30 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CXR48_RS19130 dc7c80bdd0861394e58fff67fb9e173b 149 Gene3D G3DSA:3.10.430.100 63 147 3.3E-31 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CXR48_RS19130 dc7c80bdd0861394e58fff67fb9e173b 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 9.0E-22 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS04890 e83fc9349b23c0ae900844dcc7f0bb53 429 SUPERFAMILY SSF51905 1 159 6.89E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS04890 e83fc9349b23c0ae900844dcc7f0bb53 429 Gene3D G3DSA:3.50.50.60 191 393 6.3E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS04890 e83fc9349b23c0ae900844dcc7f0bb53 429 Gene3D G3DSA:3.50.50.60 1 190 1.1E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS04890 e83fc9349b23c0ae900844dcc7f0bb53 429 SUPERFAMILY SSF51905 125 342 8.42E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS04890 e83fc9349b23c0ae900844dcc7f0bb53 429 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 1 335 6.2E-107 T 29-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 Hamap MF_00520 Ribulokinase [araB]. 1 546 52.254 T 29-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 2 540 2.7E-275 T 29-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 288 486 1.2E-42 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 Gene3D G3DSA:3.30.420.40 1 278 5.3E-51 T 29-03-2018 CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 SUPERFAMILY SSF53067 3 280 1.01E-40 T 29-03-2018 CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 PIRSF PIRSF000538 1 540 5.1E-66 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 397 417 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 Gene3D G3DSA:3.30.420.40 280 549 1.0E-58 T 29-03-2018 CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 SUPERFAMILY SSF53067 280 537 1.1E-59 T 29-03-2018 CXR48_RS13300 daf368d704458551a8cb63559f51632b 561 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 274 2.4E-15 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CXR48_RS12265 97c50fa2553b8594be73a451a44f1eba 397 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 179 382 6.4E-74 T 29-03-2018 IPR010897 Sporulation stage II, protein P CXR48_RS12265 97c50fa2553b8594be73a451a44f1eba 397 Gene3D G3DSA:3.40.630.40 174 384 4.3E-13 T 29-03-2018 CXR48_RS12265 97c50fa2553b8594be73a451a44f1eba 397 SUPERFAMILY SSF53187 240 379 5.34E-7 T 29-03-2018 CXR48_RS12265 97c50fa2553b8594be73a451a44f1eba 397 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 103 378 3.6E-76 T 29-03-2018 IPR010897 Sporulation stage II, protein P CXR48_RS18815 f36f0d428a5c36a9d467abb22db28cde 228 Gene3D G3DSA:3.10.180.10 1 130 1.5E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS18815 f36f0d428a5c36a9d467abb22db28cde 228 SUPERFAMILY SSF54593 1 120 1.0E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS18815 f36f0d428a5c36a9d467abb22db28cde 228 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 113 6.1E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS07710 88c878ff263346114a6df84606cd3c66 436 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 418 6.4E-138 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CXR48_RS07710 88c878ff263346114a6df84606cd3c66 436 Pfam PF00860 Permease family 18 393 8.4E-118 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS07710 88c878ff263346114a6df84606cd3c66 436 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 340 360 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CXR48_RS05385 ec2580517754951c8898fb303bfc6fdd 164 Pfam PF05163 DinB family 2 162 1.4E-32 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CXR48_RS05385 ec2580517754951c8898fb303bfc6fdd 164 Gene3D G3DSA:1.20.120.450 1 164 2.9E-21 T 29-03-2018 CXR48_RS05385 ec2580517754951c8898fb303bfc6fdd 164 SUPERFAMILY SSF109854 6 160 3.3E-29 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CXR48_RS16420 f45185c45d3a311111c3a71edbdacb27 589 Gene3D G3DSA:3.40.50.300 327 583 6.0E-74 T 29-03-2018 CXR48_RS16420 f45185c45d3a311111c3a71edbdacb27 589 SUPERFAMILY SSF90123 12 326 2.49E-74 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS16420 f45185c45d3a311111c3a71edbdacb27 589 Gene3D G3DSA:1.20.1560.10 2 326 1.2E-69 T 29-03-2018 CXR48_RS16420 f45185c45d3a311111c3a71edbdacb27 589 Pfam PF00664 ABC transporter transmembrane region 31 297 2.5E-45 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS16420 f45185c45d3a311111c3a71edbdacb27 589 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS16420 f45185c45d3a311111c3a71edbdacb27 589 SUPERFAMILY SSF52540 335 577 6.96E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16420 f45185c45d3a311111c3a71edbdacb27 589 SMART SM00382 366 553 1.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS16420 f45185c45d3a311111c3a71edbdacb27 589 Pfam PF00005 ABC transporter 357 507 1.5E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15190 33cd180256144ebb7735090c943da414 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 8.2E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS15190 33cd180256144ebb7735090c943da414 242 SMART SM00345 14 73 2.2E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS15190 33cd180256144ebb7735090c943da414 242 SUPERFAMILY SSF64288 61 238 1.46E-41 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS15190 33cd180256144ebb7735090c943da414 242 SMART SM00866 94 234 3.7E-25 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS15190 33cd180256144ebb7735090c943da414 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 6.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS15190 33cd180256144ebb7735090c943da414 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 6.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS15190 33cd180256144ebb7735090c943da414 242 Gene3D G3DSA:3.40.1410.10 73 240 2.0E-34 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS15190 33cd180256144ebb7735090c943da414 242 Pfam PF07702 UTRA domain 95 233 3.4E-30 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS15190 33cd180256144ebb7735090c943da414 242 SUPERFAMILY SSF46785 3 82 9.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15190 33cd180256144ebb7735090c943da414 242 Gene3D G3DSA:1.10.10.10 2 72 2.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15545 f86732c0bc48508208a80a25bee0189f 292 SUPERFAMILY SSF63829 8 287 5.23E-60 T 29-03-2018 CXR48_RS15545 f86732c0bc48508208a80a25bee0189f 292 Gene3D G3DSA:2.120.10.30 1 290 1.9E-40 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CXR48_RS15545 f86732c0bc48508208a80a25bee0189f 292 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 14 256 4.3E-78 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CXR48_RS15545 f86732c0bc48508208a80a25bee0189f 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 237 255 8.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CXR48_RS15545 f86732c0bc48508208a80a25bee0189f 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 194 211 8.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CXR48_RS15545 f86732c0bc48508208a80a25bee0189f 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 154 174 8.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CXR48_RS15545 f86732c0bc48508208a80a25bee0189f 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 8.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CXR48_RS15545 f86732c0bc48508208a80a25bee0189f 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 90 111 8.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CXR48_RS15545 f86732c0bc48508208a80a25bee0189f 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 131 153 8.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CXR48_RS04345 93ff741e9e566cc2723816ebdf961ae8 590 Pfam PF01964 Radical SAM ThiC family 133 553 3.7E-205 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CXR48_RS04345 93ff741e9e566cc2723816ebdf961ae8 590 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 132 556 1.1E-227 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CXR48_RS04345 93ff741e9e566cc2723816ebdf961ae8 590 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 132 559 57.044 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CXR48_RS04345 93ff741e9e566cc2723816ebdf961ae8 590 Pfam PF13667 ThiC-associated domain 17 93 3.1E-31 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CXR48_RS10505 34a27ea1bc0d937cb9522f6de977af7e 182 Hamap MF_01575 UPF0398 protein . 1 177 35.176 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 CXR48_RS10505 34a27ea1bc0d937cb9522f6de977af7e 182 Gene3D G3DSA:3.40.50.450 1 180 6.6E-39 T 29-03-2018 CXR48_RS10505 34a27ea1bc0d937cb9522f6de977af7e 182 PIRSF PIRSF021290 1 179 2.3E-70 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 CXR48_RS10505 34a27ea1bc0d937cb9522f6de977af7e 182 SUPERFAMILY SSF102405 1 177 3.02E-62 T 29-03-2018 CXR48_RS10505 34a27ea1bc0d937cb9522f6de977af7e 182 Pfam PF06908 Protein of unknown function (DUF1273) 4 171 6.6E-70 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 CXR48_RS09810 373e742379e9dfa195d96f5762be08db 148 SMART SM00871 1 148 2.3E-26 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CXR48_RS09810 373e742379e9dfa195d96f5762be08db 148 SUPERFAMILY SSF55136 2 148 1.15E-26 T 29-03-2018 CXR48_RS09810 373e742379e9dfa195d96f5762be08db 148 Pfam PF06445 GyrI-like small molecule binding domain 3 147 5.5E-26 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CXR48_RS09810 373e742379e9dfa195d96f5762be08db 148 Gene3D G3DSA:3.20.80.10 1 148 2.3E-26 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CXR48_RS12260 d6a62a23173d76bda7e419ad510a0b55 112 ProDom PD072942 YQXA ORF79 1 112 8.0E-38 T 29-03-2018 IPR020534 Uncharacterised protein family YqxA CXR48_RS12260 d6a62a23173d76bda7e419ad510a0b55 112 Pfam PF12438 Protein of unknown function (DUF3679) 7 62 1.1E-25 T 29-03-2018 IPR020534 Uncharacterised protein family YqxA CXR48_RS10865 a142d6695c2be86cf4aa6cce4fbdf582 218 Gene3D G3DSA:2.40.10.220 97 217 6.8E-19 T 29-03-2018 CXR48_RS10865 a142d6695c2be86cf4aa6cce4fbdf582 218 Pfam PF12945 Flagellar protein YcgR 4 89 2.1E-13 T 29-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal CXR48_RS10865 a142d6695c2be86cf4aa6cce4fbdf582 218 Gene3D G3DSA:2.30.110.10 1 96 1.6E-15 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CXR48_RS10865 a142d6695c2be86cf4aa6cce4fbdf582 218 SUPERFAMILY SSF141371 97 171 4.71E-6 T 29-03-2018 CXR48_RS10865 a142d6695c2be86cf4aa6cce4fbdf582 218 Pfam PF07238 PilZ domain 98 205 1.1E-9 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CXR48_RS16480 6943ef602b04cde47dfbc1a01f7e4f1a 271 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 261 17.91 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CXR48_RS16480 6943ef602b04cde47dfbc1a01f7e4f1a 271 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 265 1.9E-88 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CXR48_RS16480 6943ef602b04cde47dfbc1a01f7e4f1a 271 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CXR48_RS16480 6943ef602b04cde47dfbc1a01f7e4f1a 271 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 255 1.7E-77 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 Gene3D G3DSA:1.10.10.10 100 147 5.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 SUPERFAMILY SSF88659 163 251 1.27E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 248 8.2E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 PIRSF PIRSF000770 11 254 2.1E-40 T 29-03-2018 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 219 234 7.8E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 54 67 7.8E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 234 245 7.8E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 202 214 7.8E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 78 86 7.8E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 SUPERFAMILY SSF88659 100 168 8.04E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 27 249 2.3E-86 T 29-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 SUPERFAMILY SSF88946 6 99 3.14E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 219 245 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 Gene3D G3DSA:1.10.10.10 192 253 7.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 54 67 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 Gene3D G3DSA:1.10.1740.10 13 97 1.6E-19 T 29-03-2018 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 Pfam PF04545 Sigma-70, region 4 199 247 1.9E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 Pfam PF04542 Sigma-70 region 2 27 99 1.0E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08215 47dfd4ba037e2c468591740f86acba8f 254 Pfam PF04539 Sigma-70 region 3 106 184 1.2E-10 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12815 7c9d0031ae882b226a14ed01c2ecfa08 401 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 6 49 6.0E-26 T 29-03-2018 IPR014248 Spore coat assembly protein SafA CXR48_RS12815 7c9d0031ae882b226a14ed01c2ecfa08 401 SUPERFAMILY SSF54106 2 48 9.81E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS12815 7c9d0031ae882b226a14ed01c2ecfa08 401 Gene3D G3DSA:3.10.350.10 2 52 2.8E-19 T 29-03-2018 CXR48_RS12815 7c9d0031ae882b226a14ed01c2ecfa08 401 SMART SM00257 3 48 3.8E-18 T 29-03-2018 IPR018392 LysM domain CXR48_RS12815 7c9d0031ae882b226a14ed01c2ecfa08 401 Pfam PF01476 LysM domain 4 48 2.6E-15 T 29-03-2018 IPR018392 LysM domain CXR48_RS04095 d70799487935efd405d1ad2679dd6ee8 63 Pfam PF14151 YfhD-like protein 1 61 7.7E-26 T 29-03-2018 IPR025435 YfhD-like protein CXR48_RS04095 d70799487935efd405d1ad2679dd6ee8 63 ProDom PD053407 YFHD 1 63 3.0E-25 T 29-03-2018 CXR48_RS05705 f7e7dbe9d84d5c070b5440735206358a 297 Pfam PF00849 RNA pseudouridylate synthase 90 240 3.4E-28 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS05705 f7e7dbe9d84d5c070b5440735206358a 297 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 133 147 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS05705 f7e7dbe9d84d5c070b5440735206358a 297 Gene3D G3DSA:3.30.2350.10 81 297 1.8E-64 T 29-03-2018 CXR48_RS05705 f7e7dbe9d84d5c070b5440735206358a 297 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 41 296 1.8E-71 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS05705 f7e7dbe9d84d5c070b5440735206358a 297 Gene3D G3DSA:3.10.20.30 3 67 0.0024 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS05705 f7e7dbe9d84d5c070b5440735206358a 297 SUPERFAMILY SSF55120 75 295 2.4E-68 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS06765 2a826ebb3a427226fa3d73ea47fbda89 148 Pfam PF01047 MarR family 35 92 4.8E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06765 2a826ebb3a427226fa3d73ea47fbda89 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CXR48_RS06765 2a826ebb3a427226fa3d73ea47fbda89 148 SUPERFAMILY SSF46785 3 142 5.27E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06765 2a826ebb3a427226fa3d73ea47fbda89 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.6E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06765 2a826ebb3a427226fa3d73ea47fbda89 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.6E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06765 2a826ebb3a427226fa3d73ea47fbda89 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.6E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06765 2a826ebb3a427226fa3d73ea47fbda89 148 Gene3D G3DSA:1.10.10.10 1 148 2.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06765 2a826ebb3a427226fa3d73ea47fbda89 148 SMART SM00347 28 128 3.3E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 ProSitePatterns PS00480 Citrate synthase signature. 249 261 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 Pfam PF00285 Citrate synthase, C-terminal domain 5 352 2.2E-113 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 Gene3D G3DSA:1.10.580.10 309 350 1.4E-5 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 PIRSF PIRSF001369 1 366 9.6E-132 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 PRINTS PR00143 Citrate synthase signature 303 319 1.4E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 PRINTS PR00143 Citrate synthase signature 189 217 1.4E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 PRINTS PR00143 Citrate synthase signature 242 262 1.4E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 PRINTS PR00143 Citrate synthase signature 167 182 1.4E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 PRINTS PR00143 Citrate synthase signature 323 337 1.4E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 PRINTS PR00143 Citrate synthase signature 118 131 1.4E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 SUPERFAMILY SSF48256 2 363 4.45E-117 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 Gene3D G3DSA:1.10.580.10 1 230 1.7E-78 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CXR48_RS04705 edbbd468f08b050dda2562e1e593b5c4 367 Gene3D G3DSA:1.10.230.10 231 308 4.9E-28 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 9.1E-69 T 29-03-2018 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 9.1E-69 T 29-03-2018 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 9.1E-69 T 29-03-2018 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 9.1E-69 T 29-03-2018 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 9.1E-69 T 29-03-2018 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 9.1E-69 T 29-03-2018 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 45.02 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 SUPERFAMILY SSF48557 4 453 1.13E-151 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 Gene3D G3DSA:1.10.275.10 3 107 2.5E-38 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 455 1.0E-216 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 Pfam PF14698 Argininosuccinate lyase C-terminal 364 432 2.6E-24 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 Gene3D G3DSA:1.10.40.30 376 433 2.1E-25 T 29-03-2018 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 1.7E-29 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 1.7E-29 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 1.7E-29 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 1.7E-29 T 29-03-2018 IPR000362 Fumarate lyase family CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 Gene3D G3DSA:1.20.200.10 108 375 3.7E-94 T 29-03-2018 CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 Pfam PF00206 Lyase 7 301 1.2E-75 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CXR48_RS13570 6b5426073f25e0228eb72971e89037f7 458 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CXR48_RS07850 8e93efb1aa0dfdcd2bd61958e8e91d99 363 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 359 74.004 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS07850 8e93efb1aa0dfdcd2bd61958e8e91d99 363 PIRSF PIRSF006004 9 363 1.6E-141 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS07850 8e93efb1aa0dfdcd2bd61958e8e91d99 363 Pfam PF13394 4Fe-4S single cluster domain 125 226 2.9E-6 T 29-03-2018 CXR48_RS07850 8e93efb1aa0dfdcd2bd61958e8e91d99 363 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 14 363 1.3E-174 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS07850 8e93efb1aa0dfdcd2bd61958e8e91d99 363 Pfam PF04055 Radical SAM superfamily 120 293 3.7E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS07850 8e93efb1aa0dfdcd2bd61958e8e91d99 363 SUPERFAMILY SSF102114 102 315 7.59E-14 T 29-03-2018 CXR48_RS07850 8e93efb1aa0dfdcd2bd61958e8e91d99 363 Gene3D G3DSA:3.20.20.70 27 360 1.5E-40 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS04080 af36f0365ac3b19dd62d93c6423319ba 856 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 31 295 1.5E-14 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CXR48_RS04080 af36f0365ac3b19dd62d93c6423319ba 856 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 541 831 2.6E-96 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CXR48_RS04080 af36f0365ac3b19dd62d93c6423319ba 856 SUPERFAMILY SSF55729 651 830 2.33E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS04080 af36f0365ac3b19dd62d93c6423319ba 856 Gene3D G3DSA:3.40.630.30 638 824 8.6E-18 T 29-03-2018 CXR48_RS11895 8ab7205a8f7dcb506bbdd5ebeec3b4e8 276 Gene3D G3DSA:3.30.750.24 97 267 4.2E-12 T 29-03-2018 IPR002645 STAS domain CXR48_RS11895 8ab7205a8f7dcb506bbdd5ebeec3b4e8 276 Pfam PF01740 STAS domain 160 260 2.9E-14 T 29-03-2018 IPR002645 STAS domain CXR48_RS11895 8ab7205a8f7dcb506bbdd5ebeec3b4e8 276 SUPERFAMILY SSF52091 160 265 1.96E-15 T 29-03-2018 IPR002645 STAS domain CXR48_RS05845 a11c28bbec4142600ed30f946b8345f0 143 SUPERFAMILY SSF55729 5 141 6.1E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS05845 a11c28bbec4142600ed30f946b8345f0 143 Gene3D G3DSA:3.40.630.30 3 143 5.4E-35 T 29-03-2018 CXR48_RS05845 a11c28bbec4142600ed30f946b8345f0 143 Pfam PF13673 Acetyltransferase (GNAT) domain 21 140 1.0E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS04775 d51f00f00888f485fb1c3507ed282cc4 128 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 112 3.5E-21 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CXR48_RS04775 d51f00f00888f485fb1c3507ed282cc4 128 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 117 17.24 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 Gene3D G3DSA:3.40.50.450 1 211 2.2E-87 T 29-03-2018 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 Gene3D G3DSA:3.40.50.450 212 309 6.9E-9 T 29-03-2018 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 Pfam PF00365 Phosphofructokinase 3 275 1.6E-114 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.2E-89 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.2E-89 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.2E-89 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.2E-89 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.2E-89 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.2E-89 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.2E-89 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.2E-89 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.2E-89 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 1.5E-144 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 SUPERFAMILY SSF53784 1 315 2.75E-121 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 PIRSF PIRSF000532 1 319 6.7E-126 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CXR48_RS13505 6c51f8412ffe7612e14ff3c42d44ab61 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 49.711 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 Gene3D G3DSA:3.40.50.10490 62 207 1.7E-45 T 29-03-2018 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 Pfam PF00342 Phosphoglucose isomerase 76 295 6.5E-20 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 Pfam PF00342 Phosphoglucose isomerase 369 426 1.0E-5 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 Gene3D G3DSA:3.40.50.10490 1 61 3.9E-10 T 29-03-2018 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 Gene3D G3DSA:3.40.50.10490 208 434 6.8E-79 T 29-03-2018 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 26.905 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 7.7E-30 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 7.7E-30 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 7.7E-30 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 7.7E-30 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 7.7E-30 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 7.7E-30 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CXR48_RS14570 cd9ceb6bba353bf067512b231cbe7898 450 SUPERFAMILY SSF53697 5 447 3.89E-143 T 29-03-2018 CXR48_RS17590 d4d7a4d9f0d63c1e62e8d376b48f94a5 320 Pfam PF03851 UV-endonuclease UvdE 5 274 1.1E-111 T 29-03-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 CXR48_RS17590 d4d7a4d9f0d63c1e62e8d376b48f94a5 320 SUPERFAMILY SSF51658 55 277 5.93E-18 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS17590 d4d7a4d9f0d63c1e62e8d376b48f94a5 320 Hamap MF_00606 UV DNA damage endonuclease [uvsE]. 12 304 39.556 T 29-03-2018 IPR023520 UV-endonuclease UvdE, bacterial GO:0004519|GO:0009411 CXR48_RS17590 d4d7a4d9f0d63c1e62e8d376b48f94a5 320 Gene3D G3DSA:3.20.20.150 48 307 1.7E-24 T 29-03-2018 CXR48_RS17590 d4d7a4d9f0d63c1e62e8d376b48f94a5 320 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 1 303 4.0E-131 T 29-03-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 CXR48_RS13835 6091842d0a976556f86d09d7a40f99e3 269 Pfam PF07285 Protein of unknown function (DUF1444) 3 267 3.8E-128 T 29-03-2018 IPR010838 Protein of unknown unction DUF1444 CXR48_RS13835 6091842d0a976556f86d09d7a40f99e3 269 Hamap MF_01548 UPF0354 protein . 3 268 47.245 T 29-03-2018 IPR010838 Protein of unknown unction DUF1444 CXR48_RS13835 6091842d0a976556f86d09d7a40f99e3 269 PIRSF PIRSF012562 1 268 1.8E-136 T 29-03-2018 IPR010838 Protein of unknown unction DUF1444 CXR48_RS16070 4c91bdb6aab402c45bd93ddaac854e6b 305 Pfam PF00892 EamA-like transporter family 151 286 2.3E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS16070 4c91bdb6aab402c45bd93ddaac854e6b 305 Pfam PF00892 EamA-like transporter family 11 140 1.7E-25 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS16070 4c91bdb6aab402c45bd93ddaac854e6b 305 SUPERFAMILY SSF103481 43 143 1.7E-16 T 29-03-2018 CXR48_RS16070 4c91bdb6aab402c45bd93ddaac854e6b 305 SUPERFAMILY SSF103481 186 289 1.7E-10 T 29-03-2018 CXR48_RS02025 7ea646501738c10ddbf33796d85df7be 462 Pfam PF00171 Aldehyde dehydrogenase family 4 457 2.0E-175 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS02025 7ea646501738c10ddbf33796d85df7be 462 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS02025 7ea646501738c10ddbf33796d85df7be 462 Gene3D G3DSA:3.40.309.10 250 444 5.4E-74 T 29-03-2018 CXR48_RS02025 7ea646501738c10ddbf33796d85df7be 462 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 7 456 2.6E-227 T 29-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 CXR48_RS02025 7ea646501738c10ddbf33796d85df7be 462 SUPERFAMILY SSF53720 4 460 4.32E-171 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS02025 7ea646501738c10ddbf33796d85df7be 462 Gene3D G3DSA:3.40.605.10 2 249 1.2E-98 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS02025 7ea646501738c10ddbf33796d85df7be 462 PIRSF PIRSF036492 14 459 7.2E-86 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CXR48_RS03555 5f68393d8b952db81b2311aab3c9f86c 373 SUPERFAMILY SSF51905 7 172 1.5E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS03555 5f68393d8b952db81b2311aab3c9f86c 373 SUPERFAMILY SSF51905 268 364 1.5E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS03555 5f68393d8b952db81b2311aab3c9f86c 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 2.5E-18 T 29-03-2018 CXR48_RS03555 5f68393d8b952db81b2311aab3c9f86c 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 2.5E-18 T 29-03-2018 CXR48_RS03555 5f68393d8b952db81b2311aab3c9f86c 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 2.5E-18 T 29-03-2018 CXR48_RS03555 5f68393d8b952db81b2311aab3c9f86c 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.5E-18 T 29-03-2018 CXR48_RS03555 5f68393d8b952db81b2311aab3c9f86c 373 Gene3D G3DSA:3.50.50.60 1 357 1.3E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS03555 5f68393d8b952db81b2311aab3c9f86c 373 Pfam PF01494 FAD binding domain 8 340 1.0E-32 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CXR48_RS12085 6741282988715e5cbb674f0c90987a00 373 PIRSF PIRSF037489 3 373 4.5E-159 T 29-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CXR48_RS12085 6741282988715e5cbb674f0c90987a00 373 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 369 1.4E-106 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CXR48_RS12085 6741282988715e5cbb674f0c90987a00 373 Gene3D G3DSA:3.30.70.120 134 225 3.0E-40 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CXR48_RS12085 6741282988715e5cbb674f0c90987a00 373 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 349 2.4E-81 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CXR48_RS12085 6741282988715e5cbb674f0c90987a00 373 SUPERFAMILY SSF102705 6 372 7.32E-136 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CXR48_RS12085 6741282988715e5cbb674f0c90987a00 373 Gene3D G3DSA:3.40.1390.30 2 125 2.5E-37 T 29-03-2018 CXR48_RS12085 6741282988715e5cbb674f0c90987a00 373 Gene3D G3DSA:3.40.1390.30 226 361 2.3E-18 T 29-03-2018 CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 Pfam PF02817 e3 binding domain 140 174 7.2E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 SUPERFAMILY SSF51230 3 91 2.09E-25 T 29-03-2018 IPR011053 Single hybrid motif CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 Gene3D G3DSA:3.30.559.10 194 440 3.2E-91 T 29-03-2018 CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 SUPERFAMILY SSF47005 134 179 2.09E-13 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 212 440 1.5E-88 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 Pfam PF00364 Biotin-requiring enzyme 4 75 1.6E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 Gene3D G3DSA:2.40.50.100 1 82 9.5E-18 T 29-03-2018 CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 SUPERFAMILY SSF52777 201 440 4.45E-88 T 29-03-2018 CXR48_RS07275 39d5e7856d0339aebb07c730e85377dd 442 Gene3D G3DSA:4.10.320.10 128 182 2.0E-19 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS18320 c4a9da8c76ebdbd383f77fac6a907ffa 103 SUPERFAMILY SSF52794 1 102 1.94E-33 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS18320 c4a9da8c76ebdbd383f77fac6a907ffa 103 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 95 9.9E-21 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS18320 c4a9da8c76ebdbd383f77fac6a907ffa 103 Gene3D G3DSA:3.40.50.2300 2 103 1.3E-33 T 29-03-2018 CXR48_RS02415 bd71fc3e43b666dfee307088f8cda9de 335 SUPERFAMILY SSF89392 28 203 6.47E-22 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CXR48_RS02415 bd71fc3e43b666dfee307088f8cda9de 335 Gene3D G3DSA:2.50.20.10 25 213 1.3E-22 T 29-03-2018 CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 Hamap MF_01987 Ribokinase [rbsK]. 2 291 24.207 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 Pfam PF00294 pfkB family carbohydrate kinase 1 283 1.6E-74 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 SUPERFAMILY SSF53613 1 292 7.95E-78 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 PRINTS PR00990 Ribokinase signature 207 218 2.6E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 PRINTS PR00990 Ribokinase signature 6 27 2.6E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 PRINTS PR00990 Ribokinase signature 104 117 2.6E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 PRINTS PR00990 Ribokinase signature 172 187 2.6E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 PRINTS PR00990 Ribokinase signature 33 52 2.6E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 236 249 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 Gene3D G3DSA:3.40.1190.20 2 293 1.7E-81 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS16945 1e09cea98397203f4958211a1deee3b1 293 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 290 1.1E-102 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CXR48_RS07865 49f6c669a655c9436157d0e9fe774c9f 296 Pfam PF16745 RsgA N-terminal domain 3 58 5.0E-24 T 29-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CXR48_RS07865 49f6c669a655c9436157d0e9fe774c9f 296 Gene3D G3DSA:3.40.50.300 64 228 4.9E-29 T 29-03-2018 CXR48_RS07865 49f6c669a655c9436157d0e9fe774c9f 296 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 293 39.268 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CXR48_RS07865 49f6c669a655c9436157d0e9fe774c9f 296 Gene3D G3DSA:1.10.40.50 230 296 1.3E-24 T 29-03-2018 CXR48_RS07865 49f6c669a655c9436157d0e9fe774c9f 296 SUPERFAMILY SSF52540 66 294 5.37E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07865 49f6c669a655c9436157d0e9fe774c9f 296 SUPERFAMILY SSF50249 1 64 3.0E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS07865 49f6c669a655c9436157d0e9fe774c9f 296 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 41 286 4.8E-94 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CXR48_RS07865 49f6c669a655c9436157d0e9fe774c9f 296 Gene3D G3DSA:2.40.50.140 1 63 7.8E-22 T 29-03-2018 CXR48_RS07865 49f6c669a655c9436157d0e9fe774c9f 296 Pfam PF03193 RsgA GTPase 61 228 2.3E-62 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CXR48_RS11920 17457e010aa5553ff5d914e5fd4458c5 57 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 24 57 7.0E-10 T 29-03-2018 IPR024490 Protein of unknown function DUF2759 CXR48_RS11920 17457e010aa5553ff5d914e5fd4458c5 57 Pfam PF10958 Protein of unknown function (DUF2759) 6 56 1.3E-23 T 29-03-2018 IPR024490 Protein of unknown function DUF2759 CXR48_RS05710 b33a2b8653406c87ff72d3815e19607c 249 SUPERFAMILY SSF56300 2 219 1.74E-39 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS05710 b33a2b8653406c87ff72d3815e19607c 249 Pfam PF00149 Calcineurin-like phosphoesterase 5 194 2.5E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CXR48_RS05710 b33a2b8653406c87ff72d3815e19607c 249 Gene3D G3DSA:3.60.21.10 2 248 5.9E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS05710 b33a2b8653406c87ff72d3815e19607c 249 Hamap MF_01443 Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical] [prpE]. 1 245 60.21 T 29-03-2018 IPR023937 Bis(5'-nucleosyl)-tetraphosphatase PrpE GO:0004081|GO:0016151 KEGG: 00230+3.6.1.17|KEGG: 00240+3.6.1.17 CXR48_RS11820 f6790eee4152c278eb88ca262233756b 111 Gene3D G3DSA:1.10.260.40 1 111 1.2E-29 T 29-03-2018 CXR48_RS11820 f6790eee4152c278eb88ca262233756b 111 SMART SM00530 5 61 2.5E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS11820 f6790eee4152c278eb88ca262233756b 111 Pfam PF08671 Anti-repressor SinI 74 101 1.5E-12 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CXR48_RS11820 f6790eee4152c278eb88ca262233756b 111 SUPERFAMILY SSF47413 2 64 2.95E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS11820 f6790eee4152c278eb88ca262233756b 111 SUPERFAMILY SSF47406 74 107 1.23E-12 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CXR48_RS11820 f6790eee4152c278eb88ca262233756b 111 Pfam PF01381 Helix-turn-helix 6 58 3.1E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS07635 79095d75827f0e31d7acd3b4cfe6f664 265 Pfam PF00005 ABC transporter 18 169 3.4E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS07635 79095d75827f0e31d7acd3b4cfe6f664 265 Gene3D G3DSA:3.40.50.300 1 240 1.0E-50 T 29-03-2018 CXR48_RS07635 79095d75827f0e31d7acd3b4cfe6f664 265 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS07635 79095d75827f0e31d7acd3b4cfe6f664 265 SUPERFAMILY SSF52540 2 237 1.97E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07635 79095d75827f0e31d7acd3b4cfe6f664 265 SMART SM00382 27 220 2.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15430 36eb8aeba2d09e23a491ecbebe4035ef 154 Gene3D G3DSA:1.20.1260.10 1 154 3.3E-49 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS15430 36eb8aeba2d09e23a491ecbebe4035ef 154 Pfam PF00210 Ferritin-like domain 15 153 6.7E-34 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CXR48_RS15430 36eb8aeba2d09e23a491ecbebe4035ef 154 SUPERFAMILY SSF47240 13 153 7.65E-45 T 29-03-2018 IPR009078 Ferritin-like superfamily CXR48_RS15430 36eb8aeba2d09e23a491ecbebe4035ef 154 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 130 148 5.8E-16 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CXR48_RS15430 36eb8aeba2d09e23a491ecbebe4035ef 154 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 35 51 5.8E-16 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CXR48_RS15430 36eb8aeba2d09e23a491ecbebe4035ef 154 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 59 75 5.8E-16 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CXR48_RS15430 36eb8aeba2d09e23a491ecbebe4035ef 154 ProSitePatterns PS00818 Dps protein family signature 1. 35 51 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CXR48_RS15430 36eb8aeba2d09e23a491ecbebe4035ef 154 PIRSF PIRSF005900 1 154 2.2E-49 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CXR48_RS08060 98a7783c83138f2b28767323ee8dc483 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 149.756 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CXR48_RS08060 98a7783c83138f2b28767323ee8dc483 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 1.7E-130 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CXR48_RS08060 98a7783c83138f2b28767323ee8dc483 259 PIRSF PIRSF011572 1 257 6.6E-124 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CXR48_RS08060 98a7783c83138f2b28767323ee8dc483 259 Pfam PF08222 CodY helix-turn-helix domain 198 257 5.4E-37 T 29-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CXR48_RS08060 98a7783c83138f2b28767323ee8dc483 259 Pfam PF06018 CodY GAF-like domain 3 178 4.8E-83 T 29-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CXR48_RS08060 98a7783c83138f2b28767323ee8dc483 259 Gene3D G3DSA:1.10.10.10 160 259 7.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08060 98a7783c83138f2b28767323ee8dc483 259 Gene3D G3DSA:3.30.450.40 1 159 1.2E-33 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS08060 98a7783c83138f2b28767323ee8dc483 259 SUPERFAMILY SSF46785 167 256 4.85E-42 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16325 18dbd75233f5bce8a1caeaf4af2e1cd6 191 Gene3D G3DSA:3.40.50.450 1 191 1.5E-53 T 29-03-2018 CXR48_RS16325 18dbd75233f5bce8a1caeaf4af2e1cd6 191 SUPERFAMILY SSF102405 1 179 4.88E-58 T 29-03-2018 CXR48_RS16325 18dbd75233f5bce8a1caeaf4af2e1cd6 191 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 1.6E-81 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CXR48_RS16325 18dbd75233f5bce8a1caeaf4af2e1cd6 191 Pfam PF03641 Possible lysine decarboxylase 46 176 4.6E-42 T 29-03-2018 IPR031100 LOG family CXR48_RS13815 f27854f92ccd53e64de894536dd9b1be 140 SUPERFAMILY SSF58104 27 128 7.85E-5 T 29-03-2018 CXR48_RS13815 f27854f92ccd53e64de894536dd9b1be 140 Gene3D G3DSA:1.20.1480.30 20 121 3.2E-7 T 29-03-2018 CXR48_RS13815 f27854f92ccd53e64de894536dd9b1be 140 Pfam PF06103 Bacterial protein of unknown function (DUF948) 8 94 3.6E-27 T 29-03-2018 IPR009293 Uncharacterised protein family UPF0478 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 PRINTS PR00123 ATP synthase A subunit signature 78 94 2.5E-18 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 PRINTS PR00123 ATP synthase A subunit signature 146 161 2.5E-18 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 PRINTS PR00123 ATP synthase A subunit signature 162 184 2.5E-18 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 PRINTS PR00123 ATP synthase A subunit signature 223 238 2.5E-18 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 243 14.321 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 SUPERFAMILY SSF81336 72 237 1.01E-41 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 Pfam PF00119 ATP synthase A chain 20 237 5.0E-58 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 15 239 3.9E-53 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17430 7c046aca572b4189acd7381f2b83764c 244 Gene3D G3DSA:1.20.120.220 69 244 8.1E-44 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS02665 2c7b8b2a4c55dd697076abc6b103c4a7 448 Pfam PF01565 FAD binding domain 33 167 2.0E-29 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CXR48_RS02665 2c7b8b2a4c55dd697076abc6b103c4a7 448 Gene3D G3DSA:3.30.43.10 8 87 3.0E-18 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CXR48_RS02665 2c7b8b2a4c55dd697076abc6b103c4a7 448 Gene3D G3DSA:3.30.465.10 88 228 4.6E-35 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS02665 2c7b8b2a4c55dd697076abc6b103c4a7 448 Pfam PF08031 Berberine and berberine like 400 444 1.2E-20 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CXR48_RS02665 2c7b8b2a4c55dd697076abc6b103c4a7 448 SUPERFAMILY SSF56176 6 202 8.41E-46 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS18835 75bacbaf39a6df6b7e6593624244af71 641 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 2 641 39.193 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CXR48_RS18835 75bacbaf39a6df6b7e6593624244af71 641 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 4 637 4.5E-284 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CXR48_RS18835 75bacbaf39a6df6b7e6593624244af71 641 Gene3D G3DSA:3.60.21.10 17 583 5.1E-47 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS18835 75bacbaf39a6df6b7e6593624244af71 641 PIRSF PIRSF000906 1 641 0.0 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CXR48_RS18835 75bacbaf39a6df6b7e6593624244af71 641 SUPERFAMILY SSF56300 506 555 2.44E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS18835 75bacbaf39a6df6b7e6593624244af71 641 SUPERFAMILY SSF56300 172 258 2.44E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS18835 75bacbaf39a6df6b7e6593624244af71 641 SUPERFAMILY SSF56300 385 419 2.44E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS08350 451e89c9d1dd71e835e90c6b70cae486 196 PIRSF PIRSF001390 1 195 8.8E-75 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CXR48_RS08350 451e89c9d1dd71e835e90c6b70cae486 196 SUPERFAMILY SSF52507 6 191 1.31E-29 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CXR48_RS08350 451e89c9d1dd71e835e90c6b70cae486 196 Pfam PF02441 Flavoprotein 6 164 5.8E-19 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CXR48_RS08350 451e89c9d1dd71e835e90c6b70cae486 196 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 4.5E-101 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CXR48_RS08350 451e89c9d1dd71e835e90c6b70cae486 196 Gene3D G3DSA:3.40.50.1950 6 196 2.1E-28 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CXR48_RS03710 004a802922641cc983c543aa5ec8d75d 217 Gene3D G3DSA:2.40.260.10 55 210 1.2E-31 T 29-03-2018 IPR023365 Sortase domain CXR48_RS03710 004a802922641cc983c543aa5ec8d75d 217 SUPERFAMILY SSF63817 40 206 3.27E-37 T 29-03-2018 IPR023365 Sortase domain CXR48_RS03710 004a802922641cc983c543aa5ec8d75d 217 TIGRFAM TIGR01076 sortase_fam: sortase 82 205 2.7E-16 T 29-03-2018 IPR005754 Sortase family CXR48_RS03710 004a802922641cc983c543aa5ec8d75d 217 Pfam PF04203 Sortase family 84 204 3.4E-21 T 29-03-2018 IPR005754 Sortase family CXR48_RS16710 e3de262090110a8a786c3e341501d6ee 282 Gene3D G3DSA:3.30.1180.10 153 282 7.4E-40 T 29-03-2018 CXR48_RS16710 e3de262090110a8a786c3e341501d6ee 282 Gene3D G3DSA:3.40.50.10170 1 152 4.5E-51 T 29-03-2018 CXR48_RS16710 e3de262090110a8a786c3e341501d6ee 282 SUPERFAMILY SSF82549 1 281 1.46E-96 T 29-03-2018 CXR48_RS16710 e3de262090110a8a786c3e341501d6ee 282 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 278 1.6E-105 T 29-03-2018 IPR003797 DegV CXR48_RS16710 e3de262090110a8a786c3e341501d6ee 282 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 280 5.4E-102 T 29-03-2018 IPR003797 DegV CXR48_RS17190 9830ffde8e9a2b28a9877f140df2512a 131 SUPERFAMILY SSF81330 10 120 1.31E-34 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CXR48_RS17190 9830ffde8e9a2b28a9877f140df2512a 131 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 125 3.4E-56 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CXR48_RS17190 9830ffde8e9a2b28a9877f140df2512a 131 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 124 6.0E-46 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CXR48_RS17190 9830ffde8e9a2b28a9877f140df2512a 131 Gene3D G3DSA:1.20.5.220 109 125 0.0016 T 29-03-2018 CXR48_RS17190 9830ffde8e9a2b28a9877f140df2512a 131 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 127 30.421 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CXR48_RS17190 9830ffde8e9a2b28a9877f140df2512a 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 2.2E-11 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CXR48_RS17190 9830ffde8e9a2b28a9877f140df2512a 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.2E-11 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CXR48_RS17190 9830ffde8e9a2b28a9877f140df2512a 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 2.2E-11 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CXR48_RS17190 9830ffde8e9a2b28a9877f140df2512a 131 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 29-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 Pfam PF12344 Ultra-violet resistance protein B 551 593 1.5E-20 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 SMART SM00490 459 545 9.5E-21 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 Pfam PF04851 Type III restriction enzyme, res subunit 12 130 9.1E-13 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 Gene3D G3DSA:3.40.50.300 415 588 9.7E-33 T 29-03-2018 CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 Gene3D G3DSA:3.40.50.300 10 414 2.0E-32 T 29-03-2018 CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 660 45.248 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 SUPERFAMILY SSF46600 615 659 2.09E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 SUPERFAMILY SSF52540 324 582 4.6E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 658 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 Pfam PF00271 Helicase conserved C-terminal domain 440 544 5.5E-19 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 SMART SM00487 9 425 3.1E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 Gene3D G3DSA:4.10.860.10 595 661 6.6E-14 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 SUPERFAMILY SSF52540 3 414 6.93E-144 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16545 c63c531ff36767e20c5555d77b51b1fb 661 Pfam PF02151 UvrB/uvrC motif 626 659 4.2E-9 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS10430 cc6a3b06e76ff55c41ae762a28b3c8be 190 SUPERFAMILY SSF47413 9 63 4.74E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS10430 cc6a3b06e76ff55c41ae762a28b3c8be 190 Gene3D G3DSA:1.10.260.40 1 189 4.7E-5 T 29-03-2018 CXR48_RS18070 8f307487ef3186c42c4266cfcbe7c801 122 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 8 99 6.0E-36 T 29-03-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 CXR48_RS18070 8f307487ef3186c42c4266cfcbe7c801 122 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 16 89 2.0E-13 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 Hamap MF_00456 Glutamate 5-kinase [proB]. 8 262 37.458 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 SMART SM00359 281 355 5.6E-7 T 29-03-2018 IPR002478 PUA domain GO:0003723 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 TIGRFAM TIGR01027 proB: glutamate 5-kinase 8 354 8.8E-120 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 ProSitePatterns PS00902 Glutamate 5-kinase signature. 210 227 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 Pfam PF00696 Amino acid kinase family 8 234 8.0E-45 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 Pfam PF01472 PUA domain 281 350 3.0E-8 T 29-03-2018 IPR002478 PUA domain GO:0003723 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 SUPERFAMILY SSF53633 8 258 3.8E-67 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 Gene3D G3DSA:2.30.130.10 279 364 1.1E-14 T 29-03-2018 IPR002478 PUA domain GO:0003723 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 SUPERFAMILY SSF88697 281 343 1.1E-9 T 29-03-2018 IPR015947 PUA-like domain CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 PIRSF PIRSF000729 3 369 8.3E-134 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 PRINTS PR00474 Glutamate 5-kinase family signature 212 232 1.7E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 PRINTS PR00474 Glutamate 5-kinase family signature 45 59 1.7E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 PRINTS PR00474 Glutamate 5-kinase family signature 79 107 1.7E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 PRINTS PR00474 Glutamate 5-kinase family signature 119 140 1.7E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 PRINTS PR00474 Glutamate 5-kinase family signature 151 178 1.7E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS09340 c3ac5d35a0f991d65c8331cd107d4390 372 Gene3D G3DSA:3.40.1160.10 2 264 1.0E-56 T 29-03-2018 CXR48_RS11935 95ac6206f3ef699a5cd9984a9fdd50c2 375 SUPERFAMILY SSF53187 83 370 5.29E-52 T 29-03-2018 CXR48_RS11935 95ac6206f3ef699a5cd9984a9fdd50c2 375 SMART SM00631 85 366 4.5E-34 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CXR48_RS11935 95ac6206f3ef699a5cd9984a9fdd50c2 375 Pfam PF00246 Zinc carboxypeptidase 103 362 1.5E-27 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CXR48_RS11935 95ac6206f3ef699a5cd9984a9fdd50c2 375 Gene3D G3DSA:3.40.630.10 82 373 3.6E-44 T 29-03-2018 CXR48_RS11935 95ac6206f3ef699a5cd9984a9fdd50c2 375 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 109 121 3.6E-6 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CXR48_RS11935 95ac6206f3ef699a5cd9984a9fdd50c2 375 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 227 235 3.6E-6 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CXR48_RS11935 95ac6206f3ef699a5cd9984a9fdd50c2 375 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 130 144 3.6E-6 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CXR48_RS02110 e3dd0ba2df204079264e3ad487a18384 335 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 2 330 5.9E-91 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CXR48_RS02110 e3dd0ba2df204079264e3ad487a18384 335 SUPERFAMILY SSF50891 197 311 3.79E-8 T 29-03-2018 IPR029000 Cyclophilin-like domain CXR48_RS02110 e3dd0ba2df204079264e3ad487a18384 335 SMART SM00797 22 321 7.2E-142 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CXR48_RS02110 e3dd0ba2df204079264e3ad487a18384 335 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 23 304 9.1E-92 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 Gene3D G3DSA:3.50.50.60 2 420 5.6E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 Pfam PF03486 HI0933-like protein 4 412 7.1E-158 T 29-03-2018 CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 411 1.3E-147 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 SUPERFAMILY SSF160996 194 360 1.83E-46 T 29-03-2018 CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.4E-8 T 29-03-2018 CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 2.4E-8 T 29-03-2018 CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 367 389 2.4E-8 T 29-03-2018 CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 SUPERFAMILY SSF51905 357 414 2.75E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 SUPERFAMILY SSF51905 2 195 2.75E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 169 2.6E-9 T 29-03-2018 CXR48_RS13945 eec3ae051587e815a73c680a1600668b 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.6E-9 T 29-03-2018 CXR48_RS09655 5a446333b25d69c7449156a9ec5282ad 129 SUPERFAMILY SSF55331 2 128 1.51E-38 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CXR48_RS09655 5a446333b25d69c7449156a9ec5282ad 129 Gene3D G3DSA:3.30.429.10 1 129 8.4E-29 T 29-03-2018 CXR48_RS09655 5a446333b25d69c7449156a9ec5282ad 129 Pfam PF14552 Tautomerase enzyme 38 118 1.1E-30 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CXR48_RS04840 42a3c2de2b61cb181884907861e3ddb4 68 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 1.2E-22 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CXR48_RS04840 42a3c2de2b61cb181884907861e3ddb4 68 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CXR48_RS04840 42a3c2de2b61cb181884907861e3ddb4 68 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CXR48_RS03030 534b519da73bad1b6b060bc55d595d07 229 Gene3D G3DSA:3.30.420.40 1 137 2.7E-35 T 29-03-2018 CXR48_RS03030 534b519da73bad1b6b060bc55d595d07 229 SUPERFAMILY SSF53067 1 102 3.58E-26 T 29-03-2018 CXR48_RS03030 534b519da73bad1b6b060bc55d595d07 229 Pfam PF00814 Glycoprotease family 32 224 8.0E-34 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CXR48_RS03030 534b519da73bad1b6b060bc55d595d07 229 SUPERFAMILY SSF53067 108 214 4.53E-13 T 29-03-2018 CXR48_RS03030 534b519da73bad1b6b060bc55d595d07 229 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 216 1.7E-52 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CXR48_RS13245 d71bfb6bd2eb9a7ffbd58cc4757e6f42 361 Gene3D G3DSA:1.10.10.60 277 332 1.6E-5 T 29-03-2018 CXR48_RS13245 d71bfb6bd2eb9a7ffbd58cc4757e6f42 361 Pfam PF13556 PucR C-terminal helix-turn-helix domain 295 352 1.0E-19 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CXR48_RS13245 d71bfb6bd2eb9a7ffbd58cc4757e6f42 361 Pfam PF05651 Putative sugar diacid recognition 3 136 8.5E-41 T 29-03-2018 IPR008599 Putative sugar diacid recognition CXR48_RS00565 a63477ddc688b08fe17e9cad9d8ec3ce 154 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 4 151 1.3E-57 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CXR48_RS00565 a63477ddc688b08fe17e9cad9d8ec3ce 154 PIRSF PIRSF010607 1 154 4.9E-67 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CXR48_RS12195 b6c9bb71b11fe338665827888fb4c8d3 438 SUPERFAMILY SSF52096 14 195 6.19E-25 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS12195 b6c9bb71b11fe338665827888fb4c8d3 438 Pfam PF01957 NfeD-like C-terminal, partner-binding 290 437 8.2E-17 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain CXR48_RS12195 b6c9bb71b11fe338665827888fb4c8d3 438 SUPERFAMILY SSF141322 378 437 7.19E-5 T 29-03-2018 CXR48_RS12195 b6c9bb71b11fe338665827888fb4c8d3 438 Pfam PF01972 Serine dehydrogenase proteinase 65 126 2.7E-6 T 29-03-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 CXR48_RS12195 b6c9bb71b11fe338665827888fb4c8d3 438 Gene3D G3DSA:3.90.226.10 24 211 1.1E-23 T 29-03-2018 CXR48_RS12195 b6c9bb71b11fe338665827888fb4c8d3 438 Gene3D G3DSA:2.40.50.140 376 438 6.7E-8 T 29-03-2018 CXR48_RS11315 98be33c5f8c6422e7c43b737ae76da2e 248 Gene3D G3DSA:3.90.226.10 3 246 3.0E-41 T 29-03-2018 CXR48_RS11315 98be33c5f8c6422e7c43b737ae76da2e 248 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CXR48_RS11315 98be33c5f8c6422e7c43b737ae76da2e 248 SUPERFAMILY SSF52096 5 244 2.33E-45 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS11315 98be33c5f8c6422e7c43b737ae76da2e 248 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 241 2.0E-53 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CXR48_RS17205 7814dc6546b4a17bf4816a9249b968f8 273 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CXR48_RS17205 7814dc6546b4a17bf4816a9249b968f8 273 Pfam PF00460 Flagella basal body rod protein 5 35 2.8E-12 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CXR48_RS17205 7814dc6546b4a17bf4816a9249b968f8 273 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 144 1.8E-20 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CXR48_RS17205 7814dc6546b4a17bf4816a9249b968f8 273 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 157 255 2.2E-21 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CXR48_RS17205 7814dc6546b4a17bf4816a9249b968f8 273 SUPERFAMILY SSF117143 109 234 1.7E-13 T 29-03-2018 CXR48_RS17205 7814dc6546b4a17bf4816a9249b968f8 273 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 193 270 2.1E-19 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CXR48_RS04870 93c9bf34a52bc4649767961791558391 116 SUPERFAMILY SSF158622 4 114 7.06E-39 T 29-03-2018 IPR023378 YheA/YmcA-like domain CXR48_RS04870 93c9bf34a52bc4649767961791558391 116 Hamap MF_01526 UPF0342 protein . 2 113 18.999 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CXR48_RS04870 93c9bf34a52bc4649767961791558391 116 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 6 108 4.4E-26 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CXR48_RS04870 93c9bf34a52bc4649767961791558391 116 Gene3D G3DSA:1.20.1500.10 4 109 1.7E-31 T 29-03-2018 IPR023378 YheA/YmcA-like domain CXR48_RS04405 721c43f9cd2c87e9771e602353eee612 277 SUPERFAMILY SSF161098 75 256 7.98E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS04405 721c43f9cd2c87e9771e602353eee612 277 Gene3D G3DSA:1.10.3720.10 29 274 7.4E-27 T 29-03-2018 CXR48_RS04405 721c43f9cd2c87e9771e602353eee612 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 269 6.8E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS02815 8b1ad8407ca742b7513c347b3e4e73e9 542 Gene3D G3DSA:3.40.50.300 1 214 1.3E-41 T 29-03-2018 CXR48_RS02815 8b1ad8407ca742b7513c347b3e4e73e9 542 Gene3D G3DSA:3.40.50.300 252 511 5.4E-45 T 29-03-2018 CXR48_RS02815 8b1ad8407ca742b7513c347b3e4e73e9 542 SMART SM00382 29 179 1.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS02815 8b1ad8407ca742b7513c347b3e4e73e9 542 SMART SM00382 317 481 1.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS02815 8b1ad8407ca742b7513c347b3e4e73e9 542 SUPERFAMILY SSF52540 4 206 1.97E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS02815 8b1ad8407ca742b7513c347b3e4e73e9 542 SUPERFAMILY SSF52540 279 484 3.05E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS02815 8b1ad8407ca742b7513c347b3e4e73e9 542 Pfam PF12848 ABC transporter 173 251 2.2E-9 T 29-03-2018 IPR032781 ABC-transporter extension domain CXR48_RS02815 8b1ad8407ca742b7513c347b3e4e73e9 542 Pfam PF00005 ABC transporter 309 436 1.1E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS02815 8b1ad8407ca742b7513c347b3e4e73e9 542 Pfam PF00005 ABC transporter 21 133 1.5E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS16440 bda4b84b2ee564444bef1f71780cf017 212 SUPERFAMILY SSF52317 2 204 1.3E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS16440 bda4b84b2ee564444bef1f71780cf017 212 PIRSF PIRSF000495 1 207 1.2E-72 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CXR48_RS16440 bda4b84b2ee564444bef1f71780cf017 212 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 204 35.775 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CXR48_RS16440 bda4b84b2ee564444bef1f71780cf017 212 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 204 4.1E-69 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CXR48_RS16440 bda4b84b2ee564444bef1f71780cf017 212 Pfam PF00117 Glutamine amidotransferase class-I 4 201 1.3E-19 T 29-03-2018 IPR017926 Glutamine amidotransferase CXR48_RS16440 bda4b84b2ee564444bef1f71780cf017 212 Gene3D G3DSA:3.40.50.880 1 212 1.1E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS00010 4044f912762809da81387727523ec5b9 378 Gene3D G3DSA:3.10.150.10 1 129 1.9E-28 T 29-03-2018 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 SUPERFAMILY SSF55979 134 251 1.42E-27 T 29-03-2018 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 SMART SM00480 17 373 6.1E-183 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 Gene3D G3DSA:3.10.150.10 257 378 1.0E-27 T 29-03-2018 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 1.5E-39 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 Gene3D G3DSA:3.10.150.10 130 256 2.8E-33 T 29-03-2018 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 PIRSF PIRSF000804 1 378 1.0E-116 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 SUPERFAMILY SSF55979 254 377 8.64E-31 T 29-03-2018 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 6.5E-42 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 377 9.2E-138 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 251 1.7E-40 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CXR48_RS00010 4044f912762809da81387727523ec5b9 378 SUPERFAMILY SSF55979 1 127 3.37E-23 T 29-03-2018 CXR48_RS02955 d03a0f690eb572d368c0ae048ac59c50 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 2.5E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS02955 d03a0f690eb572d368c0ae048ac59c50 193 SUPERFAMILY SSF48498 79 191 1.91E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS02955 d03a0f690eb572d368c0ae048ac59c50 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS02955 d03a0f690eb572d368c0ae048ac59c50 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS02955 d03a0f690eb572d368c0ae048ac59c50 193 SUPERFAMILY SSF46689 5 81 4.57E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS02955 d03a0f690eb572d368c0ae048ac59c50 193 Gene3D G3DSA:1.10.357.10 2 193 7.0E-32 T 29-03-2018 CXR48_RS14440 034f429fcaa1b5d3fbdcc692fe929e29 222 Gene3D G3DSA:3.30.70.1450 142 222 3.6E-19 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS14440 034f429fcaa1b5d3fbdcc692fe929e29 222 SUPERFAMILY SSF116726 136 218 1.57E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS14440 034f429fcaa1b5d3fbdcc692fe929e29 222 Pfam PF02080 TrkA-C domain 154 218 4.0E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS14440 034f429fcaa1b5d3fbdcc692fe929e29 222 Pfam PF02254 TrkA-N domain 9 124 3.2E-26 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CXR48_RS14440 034f429fcaa1b5d3fbdcc692fe929e29 222 Gene3D G3DSA:3.40.50.720 1 141 9.6E-21 T 29-03-2018 CXR48_RS14440 034f429fcaa1b5d3fbdcc692fe929e29 222 SUPERFAMILY SSF51735 7 136 2.69E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS00210 4709e947cb18fc7e64d560bbf8e27389 109 SUPERFAMILY SSF54913 1 107 6.45E-12 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CXR48_RS00210 4709e947cb18fc7e64d560bbf8e27389 109 Gene3D G3DSA:3.30.70.120 1 109 1.8E-14 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CXR48_RS00210 4709e947cb18fc7e64d560bbf8e27389 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 3.5E-54 T 29-03-2018 IPR010375 Cyclic-di-AMP receptor CXR48_RS11235 45218de719a701fa5714de1a05619715 79 Pfam PF10827 Protein of unknown function (DUF2552) 2 79 1.3E-43 T 29-03-2018 IPR020157 Uncharacterised protein family YqkC CXR48_RS11235 45218de719a701fa5714de1a05619715 79 ProDom PD058987 CYTOSOLIC YQKC 21 79 6.0E-25 T 29-03-2018 IPR020157 Uncharacterised protein family YqkC CXR48_RS10075 ca0f64a150ee8b4eafb1e9bc196ee277 160 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 29-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CXR48_RS10075 ca0f64a150ee8b4eafb1e9bc196ee277 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 29-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CXR48_RS10075 ca0f64a150ee8b4eafb1e9bc196ee277 160 PIRSF PIRSF000303 1 160 2.4E-69 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CXR48_RS10075 ca0f64a150ee8b4eafb1e9bc196ee277 160 Gene3D G3DSA:3.40.30.10 1 160 6.4E-49 T 29-03-2018 CXR48_RS10075 ca0f64a150ee8b4eafb1e9bc196ee277 160 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.2E-20 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CXR48_RS10075 ca0f64a150ee8b4eafb1e9bc196ee277 160 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.2E-20 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CXR48_RS10075 ca0f64a150ee8b4eafb1e9bc196ee277 160 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.2E-20 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CXR48_RS10075 ca0f64a150ee8b4eafb1e9bc196ee277 160 Pfam PF00255 Glutathione peroxidase 3 109 2.1E-43 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CXR48_RS10075 ca0f64a150ee8b4eafb1e9bc196ee277 160 SUPERFAMILY SSF52833 1 158 2.8E-61 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS10995 ffb96008c7af5f7ee7ab184c124e956b 383 SUPERFAMILY SSF56601 1 268 2.37E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS10995 ffb96008c7af5f7ee7ab184c124e956b 383 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 268 357 2.5E-8 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS10995 ffb96008c7af5f7ee7ab184c124e956b 383 Gene3D G3DSA:3.40.710.10 21 293 2.3E-52 T 29-03-2018 CXR48_RS10995 ffb96008c7af5f7ee7ab184c124e956b 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 108 125 6.0E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CXR48_RS10995 ffb96008c7af5f7ee7ab184c124e956b 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 60 71 6.0E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CXR48_RS10995 ffb96008c7af5f7ee7ab184c124e956b 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 148 6.0E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CXR48_RS10995 ffb96008c7af5f7ee7ab184c124e956b 383 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 24 251 5.6E-75 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CXR48_RS14150 23f9efea8ab88c9e67131f8cf27e49f2 257 Gene3D G3DSA:3.40.50.1820 2 257 1.1E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14150 23f9efea8ab88c9e67131f8cf27e49f2 257 Pfam PF00326 Prolyl oligopeptidase family 64 255 8.7E-24 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CXR48_RS14150 23f9efea8ab88c9e67131f8cf27e49f2 257 SUPERFAMILY SSF53474 8 256 9.26E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14150 23f9efea8ab88c9e67131f8cf27e49f2 257 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 97 127 - T 29-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 CXR48_RS02390 3812877d7c8a8497427fd5379a036abd 511 Pfam PF00270 DEAD/DEAH box helicase 44 209 5.6E-49 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CXR48_RS02390 3812877d7c8a8497427fd5379a036abd 511 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 20 511 46.053 T 29-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 CXR48_RS02390 3812877d7c8a8497427fd5379a036abd 511 SUPERFAMILY SSF52540 88 375 8.72E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS02390 3812877d7c8a8497427fd5379a036abd 511 Gene3D G3DSA:3.40.50.300 237 511 6.6E-47 T 29-03-2018 CXR48_RS02390 3812877d7c8a8497427fd5379a036abd 511 SMART SM00487 39 236 1.2E-65 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS02390 3812877d7c8a8497427fd5379a036abd 511 Pfam PF00271 Helicase conserved C-terminal domain 245 353 2.1E-28 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS02390 3812877d7c8a8497427fd5379a036abd 511 Gene3D G3DSA:3.40.50.300 6 236 9.0E-59 T 29-03-2018 CXR48_RS02390 3812877d7c8a8497427fd5379a036abd 511 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 167 175 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CXR48_RS02390 3812877d7c8a8497427fd5379a036abd 511 SMART SM00490 272 353 7.5E-34 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS18625 5d64172ebdc897ccae4552e38e349e33 270 SUPERFAMILY SSF56784 1 269 1.02E-77 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS18625 5d64172ebdc897ccae4552e38e349e33 270 Gene3D G3DSA:3.40.50.1000 1 270 3.4E-49 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS18625 5d64172ebdc897ccae4552e38e349e33 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 263 6.8E-70 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS18625 5d64172ebdc897ccae4552e38e349e33 270 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 29-03-2018 CXR48_RS18625 5d64172ebdc897ccae4552e38e349e33 270 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 29-03-2018 CXR48_RS18625 5d64172ebdc897ccae4552e38e349e33 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 236 3.7E-27 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CXR48_RS18625 5d64172ebdc897ccae4552e38e349e33 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 263 1.7E-69 T 29-03-2018 IPR000150 Cof family GO:0016787 CXR48_RS11165 07dde7d742cc8dc0a36006d141c26da8 214 PIRSF PIRSF038973 1 214 6.3E-71 T 29-03-2018 IPR014196 Stage II sporulation protein M CXR48_RS11165 07dde7d742cc8dc0a36006d141c26da8 214 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 10 207 6.2E-80 T 29-03-2018 IPR014196 Stage II sporulation protein M CXR48_RS11165 07dde7d742cc8dc0a36006d141c26da8 214 Pfam PF01944 Stage II sporulation protein M 25 203 9.1E-26 T 29-03-2018 IPR002798 Stage II sporulation protein M-like CXR48_RS03500 e2cef9941fdd9f3f4f16d094f52313f3 189 Gene3D G3DSA:1.20.1260.10 1 184 1.1E-53 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS03500 e2cef9941fdd9f3f4f16d094f52313f3 189 Pfam PF05067 Manganese containing catalase 1 184 5.4E-79 T 29-03-2018 IPR007760 Manganese catalase CXR48_RS03500 e2cef9941fdd9f3f4f16d094f52313f3 189 SUPERFAMILY SSF47240 1 186 1.38E-68 T 29-03-2018 IPR009078 Ferritin-like superfamily CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 4.2E-60 T 29-03-2018 CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 Gene3D G3DSA:3.40.50.720 2 244 1.2E-72 T 29-03-2018 CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11365 4914f9d6523c6ec01539036a0455420c 245 SUPERFAMILY SSF51735 3 244 1.87E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS10750 f81f801e740ad0665dd4456803dd47ee 338 Pfam PF00591 Glycosyl transferase family, a/b domain 72 322 1.2E-97 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS10750 f81f801e740ad0665dd4456803dd47ee 338 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 64 5.3E-13 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS10750 f81f801e740ad0665dd4456803dd47ee 338 SUPERFAMILY SSF52418 72 329 5.63E-85 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS10750 f81f801e740ad0665dd4456803dd47ee 338 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 37.211 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CXR48_RS10750 f81f801e740ad0665dd4456803dd47ee 338 Gene3D G3DSA:1.20.970.10 1 65 2.0E-15 T 29-03-2018 CXR48_RS10750 f81f801e740ad0665dd4456803dd47ee 338 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 331 1.2E-127 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CXR48_RS10750 f81f801e740ad0665dd4456803dd47ee 338 SUPERFAMILY SSF47648 1 65 1.03E-14 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS10750 f81f801e740ad0665dd4456803dd47ee 338 Gene3D G3DSA:3.40.1030.10 69 338 1.6E-93 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CXR48_RS13840 810929fa40718c979da7e09c5ea0b4c2 107 Pfam PF00085 Thioredoxin 7 101 9.8E-17 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CXR48_RS13840 810929fa40718c979da7e09c5ea0b4c2 107 SUPERFAMILY SSF52833 2 102 1.16E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS13840 810929fa40718c979da7e09c5ea0b4c2 107 Gene3D G3DSA:3.40.30.10 1 107 7.2E-24 T 29-03-2018 CXR48_RS17105 c3539150a41ad26b4a0177a957fca9d1 581 Pfam PF14449 Pre-toxin TG 255 320 3.2E-20 T 29-03-2018 IPR027797 Pre-toxin TG domain CXR48_RS17105 c3539150a41ad26b4a0177a957fca9d1 581 Pfam PF04740 LXG domain of WXG superfamily 3 201 4.4E-48 T 29-03-2018 IPR006829 LXG domain CXR48_RS09435 96d54c17b7211ac90d544ceb1268d955 239 Gene3D G3DSA:3.60.15.10 14 234 3.3E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS09435 96d54c17b7211ac90d544ceb1268d955 239 SMART SM00849 20 212 1.1E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS09435 96d54c17b7211ac90d544ceb1268d955 239 SUPERFAMILY SSF56281 10 226 9.17E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS09435 96d54c17b7211ac90d544ceb1268d955 239 Pfam PF00753 Metallo-beta-lactamase superfamily 19 212 9.9E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS07390 817f493889071a20b417f6315c306763 309 Gene3D G3DSA:3.40.710.10 3 309 8.4E-117 T 29-03-2018 CXR48_RS07390 817f493889071a20b417f6315c306763 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 309 1.2E-123 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CXR48_RS07390 817f493889071a20b417f6315c306763 309 Pfam PF04960 Glutaminase 23 309 6.6E-111 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CXR48_RS07390 817f493889071a20b417f6315c306763 309 Hamap MF_00313 Glutaminase [glsA]. 5 309 45.139 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CXR48_RS07390 817f493889071a20b417f6315c306763 309 SUPERFAMILY SSF56601 7 309 2.29E-113 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS10980 1c8c62cef2bbe3a562e0618c9198c27e 244 Pfam PF01479 S4 domain 2 48 7.6E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS10980 1c8c62cef2bbe3a562e0618c9198c27e 244 SUPERFAMILY SSF55120 46 238 1.83E-46 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS10980 1c8c62cef2bbe3a562e0618c9198c27e 244 Gene3D G3DSA:3.30.2350.10 71 244 3.2E-44 T 29-03-2018 CXR48_RS10980 1c8c62cef2bbe3a562e0618c9198c27e 244 SUPERFAMILY SSF55174 2 67 1.94E-16 T 29-03-2018 CXR48_RS10980 1c8c62cef2bbe3a562e0618c9198c27e 244 SMART SM00363 2 63 7.1E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS10980 1c8c62cef2bbe3a562e0618c9198c27e 244 Gene3D G3DSA:3.10.290.10 1 70 1.1E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS10980 1c8c62cef2bbe3a562e0618c9198c27e 244 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CXR48_RS10980 1c8c62cef2bbe3a562e0618c9198c27e 244 Pfam PF00849 RNA pseudouridylate synthase 62 196 3.1E-25 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS10980 1c8c62cef2bbe3a562e0618c9198c27e 244 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 1.6E-52 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CXR48_RS13170 ee48c8949d95f35337cf2329f6a5f805 257 PIRSF PIRSF000090 1 257 1.1E-78 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CXR48_RS13170 ee48c8949d95f35337cf2329f6a5f805 257 Gene3D G3DSA:3.40.50.620 1 257 2.6E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS13170 ee48c8949d95f35337cf2329f6a5f805 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CXR48_RS13170 ee48c8949d95f35337cf2329f6a5f805 257 SMART SM00893 21 211 3.1E-57 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CXR48_RS13170 ee48c8949d95f35337cf2329f6a5f805 257 Pfam PF01012 Electron transfer flavoprotein domain 23 206 8.7E-45 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CXR48_RS13170 ee48c8949d95f35337cf2329f6a5f805 257 SUPERFAMILY SSF52402 1 242 1.05E-73 T 29-03-2018 CXR48_RS13870 8612ccb494ec3ff1b4815371495a2773 217 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 24 212 5.8E-69 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CXR48_RS13870 8612ccb494ec3ff1b4815371495a2773 217 Pfam PF02390 Putative methyltransferase 38 207 1.5E-51 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CXR48_RS13870 8612ccb494ec3ff1b4815371495a2773 217 Gene3D G3DSA:3.40.50.150 1 211 5.6E-30 T 29-03-2018 CXR48_RS13870 8612ccb494ec3ff1b4815371495a2773 217 SUPERFAMILY SSF53335 29 209 7.85E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS13870 8612ccb494ec3ff1b4815371495a2773 217 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 28.872 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CXR48_RS09945 6d9688cf0f15dae5c57a4a011dd0f575 198 Gene3D G3DSA:3.40.1580.10 1 182 5.2E-27 T 29-03-2018 CXR48_RS09945 6d9688cf0f15dae5c57a4a011dd0f575 198 SUPERFAMILY SSF160631 89 173 7.32E-26 T 29-03-2018 CXR48_RS09945 6d9688cf0f15dae5c57a4a011dd0f575 198 SUPERFAMILY SSF160631 2 56 7.32E-26 T 29-03-2018 CXR48_RS09945 6d9688cf0f15dae5c57a4a011dd0f575 198 SMART SM00860 23 165 5.6E-9 T 29-03-2018 IPR018958 Knr4/Smi1-like domain CXR48_RS09945 6d9688cf0f15dae5c57a4a011dd0f575 198 Pfam PF14568 SMI1-KNR4 cell-wall 26 163 1.7E-31 T 29-03-2018 CXR48_RS09715 1bfa9dad4574deb6a0ed609b61a49e79 233 Gene3D G3DSA:3.40.50.150 18 224 1.4E-27 T 29-03-2018 CXR48_RS09715 1bfa9dad4574deb6a0ed609b61a49e79 233 SUPERFAMILY SSF53335 16 183 2.15E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS09715 1bfa9dad4574deb6a0ed609b61a49e79 233 Pfam PF08241 Methyltransferase domain 40 133 8.1E-19 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CXR48_RS12800 7fc23ad7a74bb25baa4002687dfe4762 169 Pfam PF08977 Bypass of Forespore C, N terminal 40 89 1.2E-24 T 29-03-2018 IPR015071 Bypass-of-forespore C, N-terminal CXR48_RS12800 7fc23ad7a74bb25baa4002687dfe4762 169 Pfam PF08955 BofC C-terminal domain 92 165 3.3E-26 T 29-03-2018 IPR015050 Bypass of forespore C, C-terminal CXR48_RS01380 fed4d37b4ae77a498b460fc6dac4fa49 54 Pfam PF15777 Tryptophan RNA-binding attenuator protein inhibitory protein 1 52 8.0E-22 T 29-03-2018 IPR031538 Tryptophan RNA-binding attenuator protein inhibitory protein CXR48_RS01380 fed4d37b4ae77a498b460fc6dac4fa49 54 SUPERFAMILY SSF57938 8 42 4.97E-6 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CXR48_RS01380 fed4d37b4ae77a498b460fc6dac4fa49 54 Gene3D G3DSA:1.20.1580.10 5 44 1.9E-5 T 29-03-2018 CXR48_RS09460 c7b841d5bb10907983c077ff2e842fbd 260 Gene3D G3DSA:3.30.420.60 133 259 4.1E-14 T 29-03-2018 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 Gene3D G3DSA:3.40.50.300 832 1186 3.7E-27 T 29-03-2018 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 Gene3D G3DSA:3.40.50.300 1 180 1.7E-40 T 29-03-2018 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1180 24.774 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1178 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 PIRSF PIRSF005719 1 1186 0.0 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1171 4.0E-72 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 Gene3D G3DSA:1.20.120.330 219 385 1.2E-6 T 29-03-2018 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 Gene3D G3DSA:1.20.5.170 748 831 0.0033 T 29-03-2018 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 Gene3D G3DSA:1.20.5.170 663 747 4.6E-4 T 29-03-2018 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 SUPERFAMILY SSF75553 484 685 2.62E-55 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 SUPERFAMILY SSF57997 670 863 2.22E-6 T 29-03-2018 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 SUPERFAMILY SSF52540 1077 1163 9.36E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 SUPERFAMILY SSF52540 1 219 9.36E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 637 1.0E-29 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CXR48_RS07945 8e532f5c1fbf188eab8ee0165e09cd52 1186 SMART SM00968 518 637 9.6E-41 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CXR48_RS07465 85a26d8abbe0352b546b669f804c9828 79 Pfam PF14003 YlbE-like protein 13 72 1.9E-27 T 29-03-2018 IPR025613 YlbE-like protein CXR48_RS04545 aea93896d2984880bf56d8663d2a2788 276 Gene3D G3DSA:3.40.190.10 26 122 4.1E-10 T 29-03-2018 CXR48_RS04545 aea93896d2984880bf56d8663d2a2788 276 Gene3D G3DSA:3.40.190.10 123 265 2.5E-31 T 29-03-2018 CXR48_RS04545 aea93896d2984880bf56d8663d2a2788 276 SUPERFAMILY SSF53850 29 268 3.58E-54 T 29-03-2018 CXR48_RS04545 aea93896d2984880bf56d8663d2a2788 276 Pfam PF03180 NLPA lipoprotein 30 265 2.0E-62 T 29-03-2018 IPR004872 Lipoprotein NlpA family CXR48_RS01345 4153848f466d15e8a3a5723cb635f793 482 Pfam PF00324 Amino acid permease 32 476 8.4E-115 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS01345 4153848f466d15e8a3a5723cb635f793 482 PIRSF PIRSF006060 10 481 6.7E-79 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS01345 4153848f466d15e8a3a5723cb635f793 482 ProSitePatterns PS00218 Amino acid permeases signature. 57 88 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CXR48_RS02710 e54bf592fdbd6e5f1e44eca941157d68 349 Pfam PF04055 Radical SAM superfamily 105 262 4.4E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS02710 e54bf592fdbd6e5f1e44eca941157d68 349 SUPERFAMILY SSF102114 104 310 1.16E-8 T 29-03-2018 CXR48_RS02710 e54bf592fdbd6e5f1e44eca941157d68 349 Gene3D G3DSA:3.20.20.70 8 334 6.0E-23 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS02710 e54bf592fdbd6e5f1e44eca941157d68 349 PIRSF PIRSF006004 4 349 7.3E-93 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS02710 e54bf592fdbd6e5f1e44eca941157d68 349 TIGRFAM TIGR04432 rSAM_Cfr: 23S rRNA (adenine(2503)-C(8))-methyltransferase Cfr 3 342 3.6E-187 T 29-03-2018 IPR022881 Ribosomal RNA large subunit methyltransferase, Cfr GO:0070475 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6828 CXR48_RS05775 1fce855640e5b0398a81be724c975d11 160 Pfam PF10612 Spore coat protein Z 1 143 4.5E-39 T 29-03-2018 IPR019593 Spore coat protein Z/Y CXR48_RS17835 a44b99457beb923c9dd643e9f4d3f2f1 472 Pfam PF13535 ATP-grasp domain 172 333 1.8E-15 T 29-03-2018 CXR48_RS17835 a44b99457beb923c9dd643e9f4d3f2f1 472 Gene3D G3DSA:3.30.470.20 141 446 3.2E-30 T 29-03-2018 CXR48_RS17835 a44b99457beb923c9dd643e9f4d3f2f1 472 Gene3D G3DSA:3.40.50.20 1 140 2.7E-8 T 29-03-2018 CXR48_RS17835 a44b99457beb923c9dd643e9f4d3f2f1 472 SUPERFAMILY SSF56059 119 355 4.42E-32 T 29-03-2018 CXR48_RS15075 0d80722fd1573780051bc1bea82501a5 338 Gene3D G3DSA:3.90.1200.10 91 314 4.1E-12 T 29-03-2018 CXR48_RS15075 0d80722fd1573780051bc1bea82501a5 338 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 4 311 6.4E-117 T 29-03-2018 IPR014254 Spore coat protein YutH CXR48_RS15075 0d80722fd1573780051bc1bea82501a5 338 SUPERFAMILY SSF56112 3 316 1.38E-21 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS06710 744f26dbced443ff6d5575e3abec254d 165 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 158 2.4E-34 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS06710 744f26dbced443ff6d5575e3abec254d 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 159 2.0E-28 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS06710 744f26dbced443ff6d5575e3abec254d 165 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 159 37.094 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CXR48_RS06710 744f26dbced443ff6d5575e3abec254d 165 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 5 75 2.7E-6 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS06710 744f26dbced443ff6d5575e3abec254d 165 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS06710 744f26dbced443ff6d5575e3abec254d 165 Gene3D G3DSA:1.10.10.10 74 161 8.9E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06710 744f26dbced443ff6d5575e3abec254d 165 SUPERFAMILY SSF46767 77 160 8.11E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS06710 744f26dbced443ff6d5575e3abec254d 165 SUPERFAMILY SSF53155 4 83 5.1E-13 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CXR48_RS06710 744f26dbced443ff6d5575e3abec254d 165 Gene3D G3DSA:3.30.160.70 1 73 6.0E-14 T 29-03-2018 CXR48_RS08900 fc546f74355d8200ad76552c14d05b8a 57 SUPERFAMILY SSF140500 4 51 9.94E-16 T 29-03-2018 CXR48_RS08900 fc546f74355d8200ad76552c14d05b8a 57 Pfam PF09388 Spo0E like sporulation regulatory protein 6 47 1.4E-15 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CXR48_RS12610 35ac45b2c3a31cbc4d3897b7a4e8e9b3 88 Hamap MF_01507 UPF0297 protein . 1 85 28.663 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CXR48_RS12610 35ac45b2c3a31cbc4d3897b7a4e8e9b3 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 3.7E-38 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CXR48_RS12610 35ac45b2c3a31cbc4d3897b7a4e8e9b3 88 PIRSF PIRSF037258 1 88 3.8E-46 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CXR48_RS18250 e1dba38241977903c80a262edb272553 392 Gene3D G3DSA:3.40.50.1110 262 386 3.0E-4 T 29-03-2018 CXR48_RS18250 e1dba38241977903c80a262edb272553 392 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 6 384 3.7E-137 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CXR48_RS18250 e1dba38241977903c80a262edb272553 392 Pfam PF04914 DltD protein 41 385 4.5E-118 T 29-03-2018 IPR006998 DltD CXR48_RS18250 e1dba38241977903c80a262edb272553 392 SUPERFAMILY SSF52266 264 385 1.46E-6 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS18250 e1dba38241977903c80a262edb272553 392 PIRSF PIRSF021438 1 387 7.0E-149 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CXR48_RS09630 d413d13d62b793e8b26feeb22f6954c7 116 SUPERFAMILY SSF89442 1 116 3.14E-54 T 29-03-2018 IPR014934 Protein of unknown function DUF1806 CXR48_RS09630 d413d13d62b793e8b26feeb22f6954c7 116 Pfam PF08830 Protein of unknown function (DUF1806) 4 114 2.0E-51 T 29-03-2018 IPR014934 Protein of unknown function DUF1806 CXR48_RS09630 d413d13d62b793e8b26feeb22f6954c7 116 Gene3D G3DSA:2.70.180.10 1 114 1.6E-51 T 29-03-2018 IPR014934 Protein of unknown function DUF1806 CXR48_RS18095 0feb8c191005721c562015968fbedb02 513 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 513 253.135 T 29-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS18095 0feb8c191005721c562015968fbedb02 513 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 262 279 - T 29-03-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS18095 0feb8c191005721c562015968fbedb02 513 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 6 502 6.7E-225 T 29-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS18095 0feb8c191005721c562015968fbedb02 513 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 250 450 1.7E-38 T 29-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CXR48_RS18095 0feb8c191005721c562015968fbedb02 513 PIRSF PIRSF006005 1 506 6.0E-214 T 29-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CXR48_RS18095 0feb8c191005721c562015968fbedb02 513 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 50 234 1.1E-31 T 29-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CXR48_RS10270 d34a324bb988668c77968e14b07fb267 202 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 8 186 1.0E-39 T 29-03-2018 IPR006490 Phage major tail protein, phi13 family CXR48_RS10270 d34a324bb988668c77968e14b07fb267 202 Pfam PF04630 Phage tail tube protein 45 186 3.0E-9 T 29-03-2018 IPR006724 Phage tail tube protein 1 CXR48_RS19305 bfe827eaaceb4774b69227f9d97a4a93 629 Gene3D G3DSA:1.50.10.10 315 621 2.4E-34 T 29-03-2018 CXR48_RS19305 bfe827eaaceb4774b69227f9d97a4a93 629 Pfam PF03190 Protein of unknown function, DUF255 1 108 7.0E-42 T 29-03-2018 IPR004879 Domain of unknown function DUF255 CXR48_RS19305 bfe827eaaceb4774b69227f9d97a4a93 629 PIRSF PIRSF006402 1 628 2.9E-204 T 29-03-2018 IPR024705 Spermatogenesis-associated protein 20 CXR48_RS19305 bfe827eaaceb4774b69227f9d97a4a93 629 SUPERFAMILY SSF48208 130 482 8.51E-92 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CXR48_RS19305 bfe827eaaceb4774b69227f9d97a4a93 629 Gene3D G3DSA:3.40.30.10 1 117 2.2E-11 T 29-03-2018 CXR48_RS19305 bfe827eaaceb4774b69227f9d97a4a93 629 SUPERFAMILY SSF52833 1 74 7.27E-10 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS19305 bfe827eaaceb4774b69227f9d97a4a93 629 Gene3D G3DSA:1.50.10.10 162 282 5.3E-30 T 29-03-2018 CXR48_RS19305 bfe827eaaceb4774b69227f9d97a4a93 629 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 369 471 0.16 T 29-03-2018 CXR48_RS19305 bfe827eaaceb4774b69227f9d97a4a93 629 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 194 258 0.053 T 29-03-2018 CXR48_RS03525 5cca6d106e4124853eaa654d1b4f1930 120 Gene3D G3DSA:3.10.180.10 1 119 1.3E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS03525 5cca6d106e4124853eaa654d1b4f1930 120 SUPERFAMILY SSF54593 1 118 1.61E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS03525 5cca6d106e4124853eaa654d1b4f1930 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 1.5E-13 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS12295 351e90b969f6fb49595dedb49d5a006c 189 SUPERFAMILY SSF53927 8 140 6.96E-40 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CXR48_RS12295 351e90b969f6fb49595dedb49d5a006c 189 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 150 1.0E-81 T 29-03-2018 IPR013404 Competence operon E, ComEB CXR48_RS12295 351e90b969f6fb49595dedb49d5a006c 189 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CXR48_RS12295 351e90b969f6fb49595dedb49d5a006c 189 Gene3D G3DSA:3.40.140.10 3 149 5.8E-41 T 29-03-2018 CXR48_RS12295 351e90b969f6fb49595dedb49d5a006c 189 PIRSF PIRSF006019 1 151 1.1E-63 T 29-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CXR48_RS12295 351e90b969f6fb49595dedb49d5a006c 189 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 3.4E-28 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 20 206 6.5E-61 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 Pfam PF09179 TilS substrate binding domain 258 323 3.0E-5 T 29-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 SMART SM00977 385 460 8.2E-23 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 SUPERFAMILY SSF82829 213 322 1.18E-11 T 29-03-2018 CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 Pfam PF01171 PP-loop family 20 202 3.0E-62 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 Pfam PF11734 TilS substrate C-terminal domain 385 443 1.7E-14 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 Gene3D G3DSA:3.40.50.620 15 260 8.6E-44 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 385 430 1.3E-19 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 SUPERFAMILY SSF52402 7 235 1.23E-54 T 29-03-2018 CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 11 317 24.73 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CXR48_RS00410 83f2f5fb01d383799bc919b7d95b133d 472 SUPERFAMILY SSF56037 376 443 2.33E-16 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CXR48_RS07505 051729706857b796d817ffad886a02fe 340 Gene3D G3DSA:3.30.230.10 50 340 8.4E-38 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS07505 051729706857b796d817ffad886a02fe 340 Pfam PF13180 PDZ domain 127 194 1.9E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS07505 051729706857b796d817ffad886a02fe 340 SUPERFAMILY SSF54211 211 332 2.16E-22 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS07505 051729706857b796d817ffad886a02fe 340 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 230 330 2.5E-12 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CXR48_RS07505 051729706857b796d817ffad886a02fe 340 SUPERFAMILY SSF50156 127 212 3.68E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS00790 0f7263881cf43076c7839f233d9cae60 103 SUPERFAMILY SSF50104 1 100 4.36E-40 T 29-03-2018 IPR008991 Translation protein SH3-like domain CXR48_RS00790 0f7263881cf43076c7839f233d9cae60 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 7.3E-31 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00790 0f7263881cf43076c7839f233d9cae60 103 Gene3D G3DSA:2.30.30.30 1 91 3.6E-39 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CXR48_RS00790 0f7263881cf43076c7839f233d9cae60 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 23.061 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00790 0f7263881cf43076c7839f233d9cae60 103 Pfam PF00467 KOW motif 5 36 7.3E-10 T 29-03-2018 IPR005824 KOW CXR48_RS00790 0f7263881cf43076c7839f233d9cae60 103 SMART SM00739 2 29 5.3E-7 T 29-03-2018 IPR005824 KOW CXR48_RS00790 0f7263881cf43076c7839f233d9cae60 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00790 0f7263881cf43076c7839f233d9cae60 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 100 2.9E-42 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS01170 1211c3175970051881f98e810ee0a513 402 Pfam PF12698 ABC-2 family transporter protein 20 392 1.0E-33 T 29-03-2018 CXR48_RS01170 1211c3175970051881f98e810ee0a513 402 Gene3D G3DSA:3.40.1710.10 40 223 7.3E-18 T 29-03-2018 CXR48_RS05040 5f27b835b2d4d8a65e13ccddca1ae349 166 Pfam PF03992 Antibiotic biosynthesis monooxygenase 66 139 3.7E-15 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CXR48_RS05040 5f27b835b2d4d8a65e13ccddca1ae349 166 Gene3D G3DSA:3.30.70.100 59 166 4.3E-22 T 29-03-2018 CXR48_RS05040 5f27b835b2d4d8a65e13ccddca1ae349 166 SUPERFAMILY SSF54909 66 162 1.54E-23 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 PIRSF PIRSF001220 43 371 7.1E-90 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 51 59 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 37 371 1.0E-151 T 29-03-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 SMART SM00870 48 365 3.8E-138 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 Gene3D G3DSA:3.40.50.40 260 370 1.5E-27 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 PIRSF PIRSF500176 46 371 8.4E-76 T 29-03-2018 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 Pfam PF00710 Asparaginase, N-terminal 48 237 6.8E-58 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 PRINTS PR00139 Asparaginase/glutaminase family signature 129 147 1.7E-23 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 PRINTS PR00139 Asparaginase/glutaminase family signature 49 60 1.7E-23 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 PRINTS PR00139 Asparaginase/glutaminase family signature 307 325 1.7E-23 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 SUPERFAMILY SSF53774 46 370 9.55E-100 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 130 140 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CXR48_RS01470 c5254fcf7ffbdc1ed0d005ead4b72fb1 371 Gene3D G3DSA:3.40.50.1170 45 256 1.7E-55 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CXR48_RS02795 93cc7e77c75f462464de8694553fae58 405 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 397 1.8E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02795 93cc7e77c75f462464de8694553fae58 405 SMART SM00387 305 400 5.1E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02795 93cc7e77c75f462464de8694553fae58 405 Gene3D G3DSA:3.30.565.10 269 405 4.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS02795 93cc7e77c75f462464de8694553fae58 405 Pfam PF07730 Histidine kinase 200 266 3.8E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CXR48_RS02795 93cc7e77c75f462464de8694553fae58 405 SUPERFAMILY SSF55874 275 397 4.98E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS05655 5924dd5a56ee9fa5a63b4d6d78ff146d 218 Hamap MF_01124 Adapter protein MecA [mecA]. 1 216 27.921 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CXR48_RS05655 5924dd5a56ee9fa5a63b4d6d78ff146d 218 PIRSF PIRSF029008 1 218 1.4E-75 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CXR48_RS05655 5924dd5a56ee9fa5a63b4d6d78ff146d 218 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 211 1.3E-53 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CXR48_RS04675 f0b8edaad898bbe07ed1e9ec7b0338a5 144 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CXR48_RS04675 f0b8edaad898bbe07ed1e9ec7b0338a5 144 SUPERFAMILY SSF46785 2 136 1.78E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04675 f0b8edaad898bbe07ed1e9ec7b0338a5 144 Gene3D G3DSA:1.10.10.10 1 141 4.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04675 f0b8edaad898bbe07ed1e9ec7b0338a5 144 Pfam PF02082 Transcriptional regulator 1 82 2.0E-24 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CXR48_RS04675 f0b8edaad898bbe07ed1e9ec7b0338a5 144 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 133 1.2E-40 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CXR48_RS19070 74319db000eb57fc7a6a281e90396626 454 SMART SM00382 202 391 0.0047 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS19070 74319db000eb57fc7a6a281e90396626 454 Gene3D G3DSA:3.40.50.300 167 453 1.6E-79 T 29-03-2018 CXR48_RS19070 74319db000eb57fc7a6a281e90396626 454 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 1.1E-34 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CXR48_RS19070 74319db000eb57fc7a6a281e90396626 454 SUPERFAMILY SSF48024 8 119 1.57E-37 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CXR48_RS19070 74319db000eb57fc7a6a281e90396626 454 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 1.1E-119 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CXR48_RS19070 74319db000eb57fc7a6a281e90396626 454 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 9 442 1.5E-188 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CXR48_RS19070 74319db000eb57fc7a6a281e90396626 454 SUPERFAMILY SSF52540 183 433 2.03E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS19070 74319db000eb57fc7a6a281e90396626 454 Gene3D G3DSA:1.10.860.10 2 151 1.8E-48 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CXR48_RS13465 9f1d62f8c8c67f2c36e3cbec1ab28415 423 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 307 326 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CXR48_RS13465 9f1d62f8c8c67f2c36e3cbec1ab28415 423 SMART SM01329 21 418 3.7E-186 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CXR48_RS13465 9f1d62f8c8c67f2c36e3cbec1ab28415 423 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 417 1.2E-127 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CXR48_RS13465 9f1d62f8c8c67f2c36e3cbec1ab28415 423 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 423 9.9E-229 T 29-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CXR48_RS13465 9f1d62f8c8c67f2c36e3cbec1ab28415 423 Gene3D G3DSA:3.40.718.10 1 423 7.4E-139 T 29-03-2018 CXR48_RS13465 9f1d62f8c8c67f2c36e3cbec1ab28415 423 SUPERFAMILY SSF53659 3 422 5.18E-143 T 29-03-2018 CXR48_RS08730 ff4db8341049b221c511c1a870b0e779 533 Gene3D G3DSA:2.60.120.200 326 530 1.2E-37 T 29-03-2018 CXR48_RS08730 ff4db8341049b221c511c1a870b0e779 533 Gene3D G3DSA:2.115.10.20 1 325 9.0E-80 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS08730 ff4db8341049b221c511c1a870b0e779 533 SUPERFAMILY SSF49899 326 532 2.89E-67 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CXR48_RS08730 ff4db8341049b221c511c1a870b0e779 533 Pfam PF04616 Glycosyl hydrolases family 43 5 301 1.7E-109 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CXR48_RS08730 ff4db8341049b221c511c1a870b0e779 533 SUPERFAMILY SSF75005 4 319 8.14E-107 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS01510 fb8edff1f6cbec58576106b5eda5897a 373 SUPERFAMILY SSF48452 132 278 6.9E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS01510 fb8edff1f6cbec58576106b5eda5897a 373 Gene3D G3DSA:1.25.40.10 152 372 6.8E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS01510 fb8edff1f6cbec58576106b5eda5897a 373 Pfam PF13424 Tetratricopeptide repeat 187 251 1.5E-9 T 29-03-2018 CXR48_RS01510 fb8edff1f6cbec58576106b5eda5897a 373 Gene3D G3DSA:1.25.40.10 1 151 2.9E-37 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS01510 fb8edff1f6cbec58576106b5eda5897a 373 SMART SM00028 259 292 93.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS01510 fb8edff1f6cbec58576106b5eda5897a 373 SMART SM00028 180 213 68.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS01510 fb8edff1f6cbec58576106b5eda5897a 373 SMART SM00028 99 132 18.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS01510 fb8edff1f6cbec58576106b5eda5897a 373 SMART SM00028 139 172 420.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS01510 fb8edff1f6cbec58576106b5eda5897a 373 SMART SM00028 220 253 9.5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS13290 5828e74d80968a4938f9806324db5840 265 SUPERFAMILY SSF56784 8 256 6.52E-57 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS13290 5828e74d80968a4938f9806324db5840 265 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 9 233 2.2E-35 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CXR48_RS13290 5828e74d80968a4938f9806324db5840 265 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 108 6.5E-21 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CXR48_RS13290 5828e74d80968a4938f9806324db5840 265 Gene3D G3DSA:3.40.50.1000 3 262 4.8E-34 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS13290 5828e74d80968a4938f9806324db5840 265 Pfam PF13242 HAD-hyrolase-like 183 255 5.3E-19 T 29-03-2018 CXR48_RS06110 94ba2dad4bb82dbcb73d7ea73a7aeb2d 311 SMART SM00382 32 215 1.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS06110 94ba2dad4bb82dbcb73d7ea73a7aeb2d 311 Gene3D G3DSA:3.40.50.300 4 259 5.0E-58 T 29-03-2018 CXR48_RS06110 94ba2dad4bb82dbcb73d7ea73a7aeb2d 311 Pfam PF00005 ABC transporter 23 166 2.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS06110 94ba2dad4bb82dbcb73d7ea73a7aeb2d 311 SUPERFAMILY SSF52540 6 221 4.79E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS06180 b14f0df9cfac44d20b03ccc15662b7d3 201 Pfam PF05908 Poly-gamma-glutamate hydrolase 5 192 1.0E-62 T 29-03-2018 IPR008585 Poly-gamma-glutamate hydrolase CXR48_RS00455 a7f0e8ff818cac9a6037e024f0ab626f 294 SUPERFAMILY SSF56752 2 276 4.71E-68 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS00455 a7f0e8ff818cac9a6037e024f0ab626f 294 Gene3D G3DSA:3.30.470.10 1 109 8.3E-28 T 29-03-2018 CXR48_RS00455 a7f0e8ff818cac9a6037e024f0ab626f 294 ProSitePatterns PS00770 Aminotransferases class-IV signature. 180 209 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS00455 a7f0e8ff818cac9a6037e024f0ab626f 294 Gene3D G3DSA:3.20.10.10 110 257 3.3E-37 T 29-03-2018 CXR48_RS00455 a7f0e8ff818cac9a6037e024f0ab626f 294 Pfam PF01063 Amino-transferase class IV 29 254 8.7E-49 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CXR48_RS02605 e5e2540a790672898d45e32893b1e3f2 188 Gene3D G3DSA:3.40.250.10 81 185 2.3E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02605 e5e2540a790672898d45e32893b1e3f2 188 Gene3D G3DSA:3.30.110.40 4 80 6.6E-27 T 29-03-2018 IPR001455 TusA-like domain CXR48_RS02605 e5e2540a790672898d45e32893b1e3f2 188 Pfam PF00581 Rhodanese-like domain 95 180 2.6E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02605 e5e2540a790672898d45e32893b1e3f2 188 ProSitePatterns PS00380 Rhodanese signature 1. 115 126 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CXR48_RS02605 e5e2540a790672898d45e32893b1e3f2 188 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 29-03-2018 IPR001455 TusA-like domain CXR48_RS02605 e5e2540a790672898d45e32893b1e3f2 188 SUPERFAMILY SSF64307 2 74 3.4E-23 T 29-03-2018 IPR001455 TusA-like domain CXR48_RS02605 e5e2540a790672898d45e32893b1e3f2 188 SUPERFAMILY SSF52821 80 180 3.27E-32 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02605 e5e2540a790672898d45e32893b1e3f2 188 SMART SM00450 90 185 4.9E-25 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02605 e5e2540a790672898d45e32893b1e3f2 188 Pfam PF01206 Sulfurtransferase TusA 5 74 2.4E-21 T 29-03-2018 IPR001455 TusA-like domain CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 Gene3D G3DSA:3.90.190.20 338 490 2.8E-48 T 29-03-2018 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 Gene3D G3DSA:3.40.1390.10 1 97 3.1E-27 T 29-03-2018 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 Gene3D G3DSA:3.40.1190.10 98 337 1.4E-68 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 484 36.868 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 Pfam PF01225 Mur ligase family, catalytic domain 24 94 6.2E-14 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 SUPERFAMILY SSF53623 98 332 2.35E-78 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 SUPERFAMILY SSF53244 333 486 6.93E-47 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 SUPERFAMILY SSF63418 13 98 2.49E-25 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 484 1.4E-182 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 Pfam PF08245 Mur ligase middle domain 107 313 4.7E-58 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS07570 542e077aaaa1dae8953617925c05950b 490 Pfam PF02875 Mur ligase family, glutamate ligase domain 333 417 6.2E-24 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS06635 70c1789a49f34325e01de15f4dc4e91e 611 Gene3D G3DSA:2.40.50.140 199 303 1.9E-5 T 29-03-2018 CXR48_RS06635 70c1789a49f34325e01de15f4dc4e91e 611 SUPERFAMILY SSF56091 12 208 4.08E-39 T 29-03-2018 CXR48_RS06635 70c1789a49f34325e01de15f4dc4e91e 611 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 325 564 2.0E-83 T 29-03-2018 IPR014145 DNA ligase D, polymerase domain CXR48_RS06635 70c1789a49f34325e01de15f4dc4e91e 611 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 5 310 9.1E-81 T 29-03-2018 IPR014146 DNA ligase D, ligase domain CXR48_RS06635 70c1789a49f34325e01de15f4dc4e91e 611 Gene3D G3DSA:3.30.1490.70 140 198 4.8E-12 T 29-03-2018 CXR48_RS06635 70c1789a49f34325e01de15f4dc4e91e 611 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 22 30 - T 29-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CXR48_RS06635 70c1789a49f34325e01de15f4dc4e91e 611 Gene3D G3DSA:3.30.470.30 19 139 5.2E-25 T 29-03-2018 CXR48_RS06635 70c1789a49f34325e01de15f4dc4e91e 611 Pfam PF01068 ATP dependent DNA ligase domain 16 208 4.6E-35 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CXR48_RS06635 70c1789a49f34325e01de15f4dc4e91e 611 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 13 592 1.7E-192 T 29-03-2018 IPR014143 DNA ligase D CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 Pfam PF12848 ABC transporter 226 299 6.0E-13 T 29-03-2018 IPR032781 ABC-transporter extension domain CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 Gene3D G3DSA:3.40.50.300 292 552 4.7E-58 T 29-03-2018 CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 SUPERFAMILY SSF52540 4 240 2.67E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 Pfam PF00005 ABC transporter 341 469 1.2E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 Pfam PF00005 ABC transporter 20 187 2.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 SUPERFAMILY SSF52540 313 531 5.57E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 Pfam PF16326 ABC transporter C-terminal domain 556 621 4.7E-17 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 SMART SM00382 343 520 5.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 SMART SM00382 28 232 5.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03630 e4ee23398d7faa800fd0c92be7e3a8f1 629 Gene3D G3DSA:3.40.50.300 1 291 7.0E-59 T 29-03-2018 CXR48_RS05930 dc8b0136b5b30fd80b7ae37d84ae0648 370 Gene3D G3DSA:3.20.20.80 36 340 2.3E-62 T 29-03-2018 CXR48_RS05930 dc8b0136b5b30fd80b7ae37d84ae0648 370 SUPERFAMILY SSF51445 15 363 4.04E-84 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS05930 dc8b0136b5b30fd80b7ae37d84ae0648 370 Pfam PF07745 Glycosyl hydrolase family 53 40 355 2.6E-95 T 29-03-2018 IPR011683 Glycosyl hydrolase family 53 GO:0015926 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 Gene3D G3DSA:3.30.300.20 356 434 2.5E-36 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 PIRSF PIRSF006485 2 436 4.2E-174 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 Gene3D G3DSA:3.40.50.300 229 355 1.5E-15 T 29-03-2018 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 6.2E-178 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 7.5E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 8.3E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 180 336 5.6E-25 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 125 3.6E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 SUPERFAMILY SSF52540 138 434 1.5E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 SUPERFAMILY SSF52540 5 166 1.6E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.793 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 Gene3D G3DSA:1.20.120.430 2 70 4.7E-18 T 29-03-2018 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 Gene3D G3DSA:1.20.120.430 71 228 6.6E-43 T 29-03-2018 CXR48_RS10835 e35bca52b840f1c45f5e4511220435fc 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 3.7E-35 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CXR48_RS04000 d2d9b7a02e7c7b2a0692beef916f040b 253 Gene3D G3DSA:3.40.50.10490 73 252 1.9E-20 T 29-03-2018 CXR48_RS04000 d2d9b7a02e7c7b2a0692beef916f040b 253 SUPERFAMILY SSF53697 84 246 7.89E-23 T 29-03-2018 CXR48_RS04000 d2d9b7a02e7c7b2a0692beef916f040b 253 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 6.7E-29 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CXR48_RS04000 d2d9b7a02e7c7b2a0692beef916f040b 253 SUPERFAMILY SSF46689 1 73 4.84E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS04000 d2d9b7a02e7c7b2a0692beef916f040b 253 Gene3D G3DSA:1.10.10.10 1 72 1.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04000 d2d9b7a02e7c7b2a0692beef916f040b 253 Pfam PF01380 SIS domain 110 218 1.3E-17 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CXR48_RS07025 c5ae08c727c0c1a0fc30867965e5749d 81 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 4 48 3.0E-16 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 CXR48_RS07025 c5ae08c727c0c1a0fc30867965e5749d 81 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 79 3.2E-31 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 CXR48_RS07025 c5ae08c727c0c1a0fc30867965e5749d 81 Hamap MF_00506 UPF0180 protein . 2 80 27.697 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 CXR48_RS10990 e28dd471f113c27262a9b2d2b611d83c 196 Pfam PF07670 Nucleoside recognition 44 150 2.2E-11 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CXR48_RS01595 e8b2233cf2927612e324f8c44ac9620b 373 Gene3D G3DSA:3.40.630.10 1 254 1.1E-50 T 29-03-2018 CXR48_RS01595 e8b2233cf2927612e324f8c44ac9620b 373 Gene3D G3DSA:3.40.630.10 255 373 1.3E-16 T 29-03-2018 CXR48_RS01595 e8b2233cf2927612e324f8c44ac9620b 373 SUPERFAMILY SSF53187 6 185 7.14E-65 T 29-03-2018 CXR48_RS01595 e8b2233cf2927612e324f8c44ac9620b 373 SUPERFAMILY SSF53187 284 369 7.14E-65 T 29-03-2018 CXR48_RS01595 e8b2233cf2927612e324f8c44ac9620b 373 SUPERFAMILY SSF55031 173 283 1.79E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS01595 e8b2233cf2927612e324f8c44ac9620b 373 Pfam PF07687 Peptidase dimerisation domain 173 267 7.2E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS01595 e8b2233cf2927612e324f8c44ac9620b 373 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 12 359 1.1E-105 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CXR48_RS01595 e8b2233cf2927612e324f8c44ac9620b 373 Pfam PF01546 Peptidase family M20/M25/M40 69 368 5.3E-24 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS01595 e8b2233cf2927612e324f8c44ac9620b 373 PIRSF PIRSF005962 1 373 7.7E-107 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CXR48_RS10490 f42187e645cfbe52dba1ccbd33ddb04e 388 Gene3D G3DSA:3.40.50.150 162 384 9.9E-37 T 29-03-2018 CXR48_RS10490 f42187e645cfbe52dba1ccbd33ddb04e 388 SMART SM00981 57 156 1.0E-9 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CXR48_RS10490 f42187e645cfbe52dba1ccbd33ddb04e 388 SUPERFAMILY SSF53335 145 219 4.51E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS10490 f42187e645cfbe52dba1ccbd33ddb04e 388 SUPERFAMILY SSF53335 256 362 4.51E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS10490 f42187e645cfbe52dba1ccbd33ddb04e 388 Pfam PF02926 THUMP domain 18 155 3.0E-19 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CXR48_RS10490 f42187e645cfbe52dba1ccbd33ddb04e 388 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 301 307 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CXR48_RS10490 f42187e645cfbe52dba1ccbd33ddb04e 388 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 197 208 - T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS10490 f42187e645cfbe52dba1ccbd33ddb04e 388 Pfam PF01170 Putative RNA methylase family UPF0020 164 368 4.3E-67 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS17765 8d0de1ffb47cdc4ee3d1ef44c77b0c6d 433 SMART SM00471 57 187 2.7E-13 T 29-03-2018 IPR003607 HD/PDEase domain CXR48_RS17765 8d0de1ffb47cdc4ee3d1ef44c77b0c6d 433 SUPERFAMILY SSF109604 6 412 2.06E-121 T 29-03-2018 CXR48_RS17765 8d0de1ffb47cdc4ee3d1ef44c77b0c6d 433 Gene3D G3DSA:1.10.3210.10 10 312 3.6E-79 T 29-03-2018 CXR48_RS17765 8d0de1ffb47cdc4ee3d1ef44c77b0c6d 433 Pfam PF01966 HD domain 61 181 7.9E-18 T 29-03-2018 IPR006674 HD domain CXR48_RS07305 56bccfa6dbb0a9a02a164e1d0cd6db70 88 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 1 88 8.0E-39 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 CXR48_RS07305 56bccfa6dbb0a9a02a164e1d0cd6db70 88 PIRSF PIRSF037260 1 88 9.2E-39 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 CXR48_RS07305 56bccfa6dbb0a9a02a164e1d0cd6db70 88 SUPERFAMILY SSF158504 4 87 4.32E-33 T 29-03-2018 IPR023324 BH2638-like domain CXR48_RS07305 56bccfa6dbb0a9a02a164e1d0cd6db70 88 Hamap MF_01041 UPF0223 protein . 1 88 25.301 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 CXR48_RS07305 56bccfa6dbb0a9a02a164e1d0cd6db70 88 Gene3D G3DSA:1.10.220.80 12 88 3.1E-32 T 29-03-2018 IPR023324 BH2638-like domain CXR48_RS07305 56bccfa6dbb0a9a02a164e1d0cd6db70 88 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 84 6.7E-37 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 CXR48_RS03795 377f0f59992e933be896d334ab42f715 143 Gene3D G3DSA:2.60.40.790 3 143 5.6E-15 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS03795 377f0f59992e933be896d334ab42f715 143 Pfam PF00011 Hsp20/alpha crystallin family 45 141 5.0E-9 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CXR48_RS03795 377f0f59992e933be896d334ab42f715 143 SUPERFAMILY SSF49764 38 137 9.42E-16 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS17560 3bb9ade974b0dc2033b261e7c097c82a 124 Gene3D G3DSA:3.40.50.2300 2 124 1.4E-33 T 29-03-2018 CXR48_RS17560 3bb9ade974b0dc2033b261e7c097c82a 124 SUPERFAMILY SSF52172 4 120 5.55E-36 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS17560 3bb9ade974b0dc2033b261e7c097c82a 124 Pfam PF00072 Response regulator receiver domain 6 116 4.4E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS17560 3bb9ade974b0dc2033b261e7c097c82a 124 SMART SM00448 4 115 1.3E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS14080 b07c91618676cb94c0b4b899506de0d8 370 Pfam PF01022 Bacterial regulatory protein, arsR family 287 333 1.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS14080 b07c91618676cb94c0b4b899506de0d8 370 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 329 344 8.5E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS14080 b07c91618676cb94c0b4b899506de0d8 370 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 314 329 8.5E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS14080 b07c91618676cb94c0b4b899506de0d8 370 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 282 297 8.5E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS14080 b07c91618676cb94c0b4b899506de0d8 370 SUPERFAMILY SSF46785 275 357 1.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14080 b07c91618676cb94c0b4b899506de0d8 370 SMART SM00418 280 358 1.7E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS14080 b07c91618676cb94c0b4b899506de0d8 370 Gene3D G3DSA:1.10.10.10 258 364 7.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07000 0b742b5075d2a45028146ad2c105c3b1 157 SUPERFAMILY SSF52218 1 147 1.59E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS07000 0b742b5075d2a45028146ad2c105c3b1 157 Pfam PF00258 Flavodoxin 7 138 5.5E-30 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CXR48_RS07000 0b742b5075d2a45028146ad2c105c3b1 157 PRINTS PR00369 Flavodoxin signature 82 92 4.6E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS07000 0b742b5075d2a45028146ad2c105c3b1 157 PRINTS PR00369 Flavodoxin signature 53 64 4.6E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS07000 0b742b5075d2a45028146ad2c105c3b1 157 PRINTS PR00369 Flavodoxin signature 5 18 4.6E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CXR48_RS07000 0b742b5075d2a45028146ad2c105c3b1 157 TIGRFAM TIGR01753 flav_short: flavodoxin 5 143 6.8E-43 T 29-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 CXR48_RS07000 0b742b5075d2a45028146ad2c105c3b1 157 Gene3D G3DSA:3.40.50.360 1 151 4.3E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 246 266 1.2E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 181 1.2E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 130 1.2E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 229 1.2E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 210 1.2E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 44 61 1.2E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 178 206 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 SUPERFAMILY SSF51735 41 283 3.1E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 Gene3D G3DSA:3.40.50.720 1 285 9.4E-80 T 29-03-2018 CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 179 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 130 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 191 210 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS02155 a6b9bfc535cc5164a62d3554df1d388c 286 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 52 281 3.1E-64 T 29-03-2018 CXR48_RS18615 98cc7eb1871528ba584dc75361eefc87 222 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 212 1.6E-95 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CXR48_RS18615 98cc7eb1871528ba584dc75361eefc87 222 Pfam PF01791 DeoC/LacD family aldolase 10 210 4.2E-23 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CXR48_RS18615 98cc7eb1871528ba584dc75361eefc87 222 PIRSF PIRSF001357 1 219 7.4E-78 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CXR48_RS18615 98cc7eb1871528ba584dc75361eefc87 222 SUPERFAMILY SSF51569 2 213 7.01E-83 T 29-03-2018 CXR48_RS18615 98cc7eb1871528ba584dc75361eefc87 222 SMART SM01133 2 214 2.1E-104 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CXR48_RS18615 98cc7eb1871528ba584dc75361eefc87 222 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 216 37.322 T 29-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CXR48_RS18615 98cc7eb1871528ba584dc75361eefc87 222 Gene3D G3DSA:3.20.20.70 1 216 3.2E-96 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS05055 32f876dd4b1a7a479508622d9cc5dadd 311 Gene3D G3DSA:3.40.50.1400 159 290 1.7E-40 T 29-03-2018 CXR48_RS05055 32f876dd4b1a7a479508622d9cc5dadd 311 TIGRFAM TIGR00109 hemH: ferrochelatase 3 309 6.1E-107 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CXR48_RS05055 32f876dd4b1a7a479508622d9cc5dadd 311 ProSitePatterns PS00534 Ferrochelatase signature. 179 197 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CXR48_RS05055 32f876dd4b1a7a479508622d9cc5dadd 311 Pfam PF00762 Ferrochelatase 6 308 1.9E-84 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CXR48_RS05055 32f876dd4b1a7a479508622d9cc5dadd 311 Gene3D G3DSA:3.40.50.1400 2 158 1.5E-29 T 29-03-2018 CXR48_RS05055 32f876dd4b1a7a479508622d9cc5dadd 311 Hamap MF_00323 Ferrochelatase [hemH]. 5 309 33.392 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CXR48_RS05055 32f876dd4b1a7a479508622d9cc5dadd 311 SUPERFAMILY SSF53800 4 309 2.45E-91 T 29-03-2018 CXR48_RS00830 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 SUPERFAMILY SSF52080 4 143 4.84E-50 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CXR48_RS00830 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.892 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CXR48_RS00830 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00830 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 Gene3D G3DSA:3.100.10.10 42 146 1.9E-33 T 29-03-2018 CXR48_RS00830 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 1.3E-38 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CXR48_RS00830 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.4E-56 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS17820 bc11bc6e90ea1aef94b034a6126e034c 259 SUPERFAMILY SSF51735 3 255 2.62E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS17820 bc11bc6e90ea1aef94b034a6126e034c 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 254 3.7E-40 T 29-03-2018 CXR48_RS17820 bc11bc6e90ea1aef94b034a6126e034c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17820 bc11bc6e90ea1aef94b034a6126e034c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17820 bc11bc6e90ea1aef94b034a6126e034c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17820 bc11bc6e90ea1aef94b034a6126e034c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17820 bc11bc6e90ea1aef94b034a6126e034c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17820 bc11bc6e90ea1aef94b034a6126e034c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS17820 bc11bc6e90ea1aef94b034a6126e034c 259 Gene3D G3DSA:3.40.50.720 2 259 7.1E-53 T 29-03-2018 CXR48_RS01675 565b159cf104afab5c38d84709705046 436 PIRSF PIRSF002808 2 435 6.6E-36 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CXR48_RS01675 565b159cf104afab5c38d84709705046 436 Gene3D G3DSA:1.20.1250.20 233 433 1.4E-25 T 29-03-2018 CXR48_RS01675 565b159cf104afab5c38d84709705046 436 Gene3D G3DSA:1.20.1250.20 12 213 1.8E-40 T 29-03-2018 CXR48_RS01675 565b159cf104afab5c38d84709705046 436 Pfam PF07690 Major Facilitator Superfamily 28 392 1.9E-56 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS01675 565b159cf104afab5c38d84709705046 436 SUPERFAMILY SSF103473 14 432 2.09E-81 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01675 565b159cf104afab5c38d84709705046 436 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 31 427 9.7E-122 T 29-03-2018 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 CXR48_RS14850 42c833e9f6a2651e13aa038650c1de57 79 PIRSF PIRSF037793 1 79 3.4E-32 T 29-03-2018 IPR014921 EsaB CXR48_RS14850 42c833e9f6a2651e13aa038650c1de57 79 SUPERFAMILY SSF54236 5 78 5.06E-5 T 29-03-2018 IPR029071 Ubiquitin-related domain CXR48_RS14850 42c833e9f6a2651e13aa038650c1de57 79 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 3 78 1.2E-13 T 29-03-2018 IPR024962 YukD-like CXR48_RS14850 42c833e9f6a2651e13aa038650c1de57 79 Gene3D G3DSA:3.10.20.90 2 79 1.7E-4 T 29-03-2018 CXR48_RS10720 3ff5fcc47d8620274902e46043564d42 371 SUPERFAMILY SSF55021 294 352 8.09E-9 T 29-03-2018 CXR48_RS10720 3ff5fcc47d8620274902e46043564d42 371 Pfam PF01842 ACT domain 301 350 5.9E-10 T 29-03-2018 IPR002912 ACT domain CXR48_RS10720 3ff5fcc47d8620274902e46043564d42 371 Gene3D G3DSA:1.10.3660.10 186 292 9.5E-26 T 29-03-2018 CXR48_RS10720 3ff5fcc47d8620274902e46043564d42 371 Pfam PF02153 Prephenate dehydrogenase 20 278 1.4E-92 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CXR48_RS10720 3ff5fcc47d8620274902e46043564d42 371 Gene3D G3DSA:3.40.50.720 1 177 3.8E-23 T 29-03-2018 CXR48_RS10720 3ff5fcc47d8620274902e46043564d42 371 SUPERFAMILY SSF51735 8 174 1.38E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS10720 3ff5fcc47d8620274902e46043564d42 371 Gene3D G3DSA:3.30.70.260 297 366 1.3E-10 T 29-03-2018 CXR48_RS10720 3ff5fcc47d8620274902e46043564d42 371 SUPERFAMILY SSF48179 178 287 1.81E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS14645 a67069e69bcda1004657d08b4a365987 128 SMART SM01298 14 126 1.7E-79 T 29-03-2018 IPR014916 Kinase associated protein B CXR48_RS14645 a67069e69bcda1004657d08b4a365987 128 SUPERFAMILY SSF141251 3 125 7.06E-55 T 29-03-2018 CXR48_RS14645 a67069e69bcda1004657d08b4a365987 128 Pfam PF08810 Kinase associated protein B 14 125 1.2E-48 T 29-03-2018 IPR014916 Kinase associated protein B CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 Gene3D G3DSA:1.10.260.40 4 56 4.8E-21 T 29-03-2018 CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 Gene3D G3DSA:3.40.50.2300 57 171 4.6E-32 T 29-03-2018 CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 SMART SM00354 2 72 7.1E-34 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.2E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.2E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 SUPERFAMILY SSF53822 59 318 3.93E-65 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 Gene3D G3DSA:3.40.50.2300 172 303 6.7E-34 T 29-03-2018 CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 Pfam PF13377 Periplasmic binding protein-like domain 166 324 9.2E-26 T 29-03-2018 CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 8.8E-22 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 29-03-2018 CXR48_RS16300 b76a3c8648d83330755b42dc117b35cb 324 SUPERFAMILY SSF47413 2 61 5.63E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS06855 8eb86b4a0f36c89818282fe33e718db5 364 Gene3D G3DSA:3.90.230.10 136 363 2.1E-76 T 29-03-2018 CXR48_RS06855 8eb86b4a0f36c89818282fe33e718db5 364 SUPERFAMILY SSF55920 139 363 3.4E-76 T 29-03-2018 IPR000994 Peptidase M24 CXR48_RS06855 8eb86b4a0f36c89818282fe33e718db5 364 Pfam PF00557 Metallopeptidase family M24 146 347 2.0E-63 T 29-03-2018 IPR000994 Peptidase M24 CXR48_RS06855 8eb86b4a0f36c89818282fe33e718db5 364 SUPERFAMILY SSF53092 1 135 2.96E-32 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CXR48_RS06855 8eb86b4a0f36c89818282fe33e718db5 364 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 293 305 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CXR48_RS06855 8eb86b4a0f36c89818282fe33e718db5 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 217 233 7.6E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS06855 8eb86b4a0f36c89818282fe33e718db5 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 315 327 7.6E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CXR48_RS06855 8eb86b4a0f36c89818282fe33e718db5 364 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 137 5.1E-23 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CXR48_RS06855 8eb86b4a0f36c89818282fe33e718db5 364 Gene3D G3DSA:3.40.350.10 2 135 1.8E-24 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CXR48_RS08410 821bd1e2608b6dd2abfe38b689de44f9 426 SUPERFAMILY SSF63411 12 224 1.4E-24 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CXR48_RS08410 821bd1e2608b6dd2abfe38b689de44f9 426 Gene3D G3DSA:3.30.830.10 10 231 1.8E-26 T 29-03-2018 CXR48_RS08410 821bd1e2608b6dd2abfe38b689de44f9 426 Gene3D G3DSA:3.30.830.10 240 417 9.0E-30 T 29-03-2018 CXR48_RS08410 821bd1e2608b6dd2abfe38b689de44f9 426 SUPERFAMILY SSF63411 246 414 2.17E-31 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CXR48_RS08410 821bd1e2608b6dd2abfe38b689de44f9 426 Pfam PF05193 Peptidase M16 inactive domain 185 357 6.5E-26 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CXR48_RS03615 e2962afcb5e99da25278fe921950a8ad 284 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 150 280 5.9E-30 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS03615 e2962afcb5e99da25278fe921950a8ad 284 Gene3D G3DSA:1.10.287.950 108 283 3.0E-39 T 29-03-2018 CXR48_RS03615 e2962afcb5e99da25278fe921950a8ad 284 SUPERFAMILY SSF103190 52 115 5.49E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS03615 e2962afcb5e99da25278fe921950a8ad 284 SMART SM00283 99 283 5.7E-5 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CXR48_RS03615 e2962afcb5e99da25278fe921950a8ad 284 SUPERFAMILY SSF58104 114 280 8.11E-41 T 29-03-2018 CXR48_RS00820 11a018184bcfa65811143630ecf34458 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 1.4E-73 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CXR48_RS00820 11a018184bcfa65811143630ecf34458 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 2.0E-30 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CXR48_RS00820 11a018184bcfa65811143630ecf34458 166 Gene3D G3DSA:3.30.230.10 76 166 7.0E-33 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CXR48_RS00820 11a018184bcfa65811143630ecf34458 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.395 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CXR48_RS00820 11a018184bcfa65811143630ecf34458 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 2.0E-32 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CXR48_RS00820 11a018184bcfa65811143630ecf34458 166 Gene3D G3DSA:3.30.160.20 10 72 1.0E-30 T 29-03-2018 CXR48_RS00820 11a018184bcfa65811143630ecf34458 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CXR48_RS00820 11a018184bcfa65811143630ecf34458 166 SUPERFAMILY SSF54768 9 76 5.55E-25 T 29-03-2018 CXR48_RS00820 11a018184bcfa65811143630ecf34458 166 SUPERFAMILY SSF54211 80 159 7.08E-26 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS01820 76662bd5d6f549a0c5fd8ed496bece10 247 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS01820 76662bd5d6f549a0c5fd8ed496bece10 247 Pfam PF00005 ABC transporter 17 169 5.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS01820 76662bd5d6f549a0c5fd8ed496bece10 247 Gene3D G3DSA:3.40.50.300 1 246 1.3E-71 T 29-03-2018 CXR48_RS01820 76662bd5d6f549a0c5fd8ed496bece10 247 SUPERFAMILY SSF52540 1 239 2.24E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01820 76662bd5d6f549a0c5fd8ed496bece10 247 PIRSF PIRSF039085 1 245 2.3E-112 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CXR48_RS01820 76662bd5d6f549a0c5fd8ed496bece10 247 SMART SM00382 26 223 7.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 98 1.0E-21 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 Gene3D G3DSA:3.40.140.10 1 123 1.6E-36 T 29-03-2018 CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 PIRSF PIRSF006769 1 360 7.7E-131 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 Pfam PF01872 RibD C-terminal domain 146 354 3.3E-65 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 SUPERFAMILY SSF53597 143 355 9.16E-62 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 49 87 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 6 355 2.8E-145 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 145 356 1.1E-78 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 Gene3D G3DSA:3.40.430.10 124 356 7.0E-73 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CXR48_RS11050 1426d3e52a329b635adf44b6e008f110 371 SUPERFAMILY SSF53927 1 144 1.84E-48 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CXR48_RS18865 2748c469acc513593a7531f72353596a 338 Pfam PF06081 Aromatic acid exporter family member 1 14 149 1.5E-18 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CXR48_RS18865 2748c469acc513593a7531f72353596a 338 Gene3D G3DSA:1.20.120.20 152 303 8.0E-4 T 29-03-2018 CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 Pfam PF00106 short chain dehydrogenase 8 195 2.2E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.9E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.9E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.9E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.9E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.9E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.9E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 SUPERFAMILY SSF51735 7 259 1.62E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 Gene3D G3DSA:3.40.50.720 4 261 4.5E-65 T 29-03-2018 CXR48_RS15540 e262a95cc3b39cad8c2796970f8cc916 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS06640 e7c67b6bc7e66ee32ce9b50f9581ca74 293 Gene3D G3DSA:2.40.290.10 1 177 4.6E-32 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain CXR48_RS06640 e7c67b6bc7e66ee32ce9b50f9581ca74 293 PIRSF PIRSF006493 1 291 9.9E-109 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CXR48_RS06640 e7c67b6bc7e66ee32ce9b50f9581ca74 293 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 189 8.2E-42 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CXR48_RS06640 e7c67b6bc7e66ee32ce9b50f9581ca74 293 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 255 32.882 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CXR48_RS06640 e7c67b6bc7e66ee32ce9b50f9581ca74 293 SMART SM00559 52 181 1.4E-48 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CXR48_RS06640 e7c67b6bc7e66ee32ce9b50f9581ca74 293 SUPERFAMILY SSF100939 2 260 2.94E-54 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain CXR48_RS06640 e7c67b6bc7e66ee32ce9b50f9581ca74 293 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 257 2.7E-98 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 Gene3D G3DSA:3.40.190.80 154 263 1.9E-28 T 29-03-2018 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 Gene3D G3DSA:3.30.540.10 1 153 1.8E-42 T 29-03-2018 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 2.2E-38 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 179 200 2.2E-38 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.2E-38 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 2.2E-38 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 2.2E-38 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 2.2E-38 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 Pfam PF00459 Inositol monophosphatase family 5 254 1.0E-66 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CXR48_RS07325 f1c4869e1c0eb5c1de767c40d1c894ef 265 SUPERFAMILY SSF56655 3 258 1.44E-78 T 29-03-2018 CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 Pfam PF01546 Peptidase family M20/M25/M40 141 403 5.0E-15 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 PIRSF PIRSF037215 1 410 2.6E-196 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 Pfam PF07687 Peptidase dimerisation domain 209 308 3.1E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 Gene3D G3DSA:3.40.630.10 1 410 1.6E-52 T 29-03-2018 CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 SUPERFAMILY SSF53187 324 406 3.52E-84 T 29-03-2018 CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 SUPERFAMILY SSF53187 3 212 3.52E-84 T 29-03-2018 CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 Hamap MF_00550 Peptidase T [pepT]. 2 406 60.242 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 SUPERFAMILY SSF55031 211 322 2.44E-41 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS18430 6c7ce4cbe8b7d51bd55e573daa511100 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 410 1.2E-212 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CXR48_RS13130 11d27a209b477e026b776a186d757829 202 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 91 192 3.9E-12 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13130 11d27a209b477e026b776a186d757829 202 Gene3D G3DSA:1.20.1300.10 2 202 9.0E-45 T 29-03-2018 CXR48_RS13130 11d27a209b477e026b776a186d757829 202 SUPERFAMILY SSF81343 4 201 1.96E-61 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CXR48_RS13130 11d27a209b477e026b776a186d757829 202 PIRSF PIRSF000170 1 202 4.0E-104 T 29-03-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute CXR48_RS13130 11d27a209b477e026b776a186d757829 202 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 5 202 1.1E-67 T 29-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit CXR48_RS05560 894bed1271d727a35cdbac667fae83d4 312 Gene3D G3DSA:3.40.47.10 161 310 2.0E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05560 894bed1271d727a35cdbac667fae83d4 312 Gene3D G3DSA:3.40.47.10 1 160 1.5E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05560 894bed1271d727a35cdbac667fae83d4 312 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 310 1.1E-143 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CXR48_RS05560 894bed1271d727a35cdbac667fae83d4 312 SUPERFAMILY SSF53901 3 310 1.72E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS05560 894bed1271d727a35cdbac667fae83d4 312 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 2.9E-30 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CXR48_RS05560 894bed1271d727a35cdbac667fae83d4 312 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 221 310 6.8E-36 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CXR48_RS05560 894bed1271d727a35cdbac667fae83d4 312 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 310 71.187 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CXR48_RS16850 c2e7cec6aa79ea4001cd7fbb2c17ad22 316 SUPERFAMILY SSF51182 3 315 6.08E-104 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS16850 c2e7cec6aa79ea4001cd7fbb2c17ad22 316 Pfam PF01238 Phosphomannose isomerase type I 7 315 3.6E-66 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CXR48_RS16850 c2e7cec6aa79ea4001cd7fbb2c17ad22 316 Gene3D G3DSA:2.60.120.10 1 224 6.8E-58 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS16850 c2e7cec6aa79ea4001cd7fbb2c17ad22 316 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 104 315 3.5E-61 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CXR48_RS16850 c2e7cec6aa79ea4001cd7fbb2c17ad22 316 PIRSF PIRSF036894 3 316 5.6E-127 T 29-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CXR48_RS16850 c2e7cec6aa79ea4001cd7fbb2c17ad22 316 Gene3D G3DSA:2.60.120.10 228 316 5.3E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS17195 a2cd16e81924e2e827291b3589100334 141 Pfam PF07977 FabA-like domain 11 134 5.8E-37 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CXR48_RS17195 a2cd16e81924e2e827291b3589100334 141 Gene3D G3DSA:3.10.129.10 1 141 2.3E-55 T 29-03-2018 CXR48_RS17195 a2cd16e81924e2e827291b3589100334 141 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 6.8E-58 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CXR48_RS17195 a2cd16e81924e2e827291b3589100334 141 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 34.624 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CXR48_RS17195 a2cd16e81924e2e827291b3589100334 141 SUPERFAMILY SSF54637 1 138 2.7E-48 T 29-03-2018 IPR029069 HotDog domain CXR48_RS16140 d7ba199e904f2a35858f01bf7eb3a7bc 390 Gene3D G3DSA:3.90.1150.10 246 388 6.5E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS16140 d7ba199e904f2a35858f01bf7eb3a7bc 390 Gene3D G3DSA:3.40.640.10 6 245 1.3E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS16140 d7ba199e904f2a35858f01bf7eb3a7bc 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 373 4.9E-99 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CXR48_RS16140 d7ba199e904f2a35858f01bf7eb3a7bc 390 SUPERFAMILY SSF53383 6 378 3.63E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS16140 d7ba199e904f2a35858f01bf7eb3a7bc 390 PIRSF PIRSF000390 2 381 2.3E-113 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 SUPERFAMILY SSF54897 37 106 5.61E-23 T 29-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 135 146 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 326 336 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 Pfam PF05922 Peptidase inhibitor I9 39 105 8.2E-5 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 Pfam PF00082 Subtilase family 130 372 3.5E-63 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 Gene3D G3DSA:3.40.50.200 94 382 1.3E-95 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 PRINTS PR00723 Subtilisin serine protease family (S8) signature 325 341 7.7E-24 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 PRINTS PR00723 Subtilisin serine protease family (S8) signature 130 149 7.7E-24 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 PRINTS PR00723 Subtilisin serine protease family (S8) signature 167 180 7.7E-24 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 171 181 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 SUPERFAMILY SSF52743 108 381 3.53E-93 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS05130 61ffa1bc232445d505551a8d8629c110 382 Gene3D G3DSA:3.30.70.80 36 93 3.0E-13 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CXR48_RS09800 70ce014c7c52c32f0e96de9bf22de3a2 229 Gene3D G3DSA:3.40.1080.10 4 227 1.3E-71 T 29-03-2018 CXR48_RS09800 70ce014c7c52c32f0e96de9bf22de3a2 229 SUPERFAMILY SSF100950 6 223 1.33E-73 T 29-03-2018 CXR48_RS09800 70ce014c7c52c32f0e96de9bf22de3a2 229 SMART SM00882 7 219 7.6E-77 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS09800 70ce014c7c52c32f0e96de9bf22de3a2 229 Pfam PF01144 Coenzyme A transferase 10 218 2.0E-68 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS09800 70ce014c7c52c32f0e96de9bf22de3a2 229 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 9 220 2.4E-67 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 150 155 1.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 155 164 1.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 103 113 1.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 93 102 1.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 181 189 1.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 129 135 1.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 Gene3D G3DSA:2.60.120.180 7 213 3.1E-71 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 SUPERFAMILY SSF49899 33 213 2.96E-71 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 103 113 - T 29-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 CXR48_RS17305 aa653bdbedb1378745c08a49576a3912 213 Pfam PF00457 Glycosyl hydrolases family 11 31 211 6.2E-69 T 29-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 CXR48_RS05615 adbfcd16cb4448d77108ed43f72ef873 311 Gene3D G3DSA:1.10.3720.10 3 292 1.1E-42 T 29-03-2018 CXR48_RS05615 adbfcd16cb4448d77108ed43f72ef873 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 2.1E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS05615 adbfcd16cb4448d77108ed43f72ef873 311 SUPERFAMILY SSF161098 88 291 8.34E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS16925 1cb63b2c137f096c6362317436c28591 489 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 20 467 3.9E-167 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS16925 1cb63b2c137f096c6362317436c28591 489 PIRSF PIRSF005690 5 482 9.3E-165 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS10525 6c7d8bae6f339b4b7a2550cd5930989b 168 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 19 142 3.3E-51 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CXR48_RS10525 6c7d8bae6f339b4b7a2550cd5930989b 168 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 20 140 4.7E-45 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CXR48_RS10525 6c7d8bae6f339b4b7a2550cd5930989b 168 Gene3D G3DSA:2.70.70.10 8 167 4.6E-59 T 29-03-2018 CXR48_RS10525 6c7d8bae6f339b4b7a2550cd5930989b 168 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 82 94 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CXR48_RS10525 6c7d8bae6f339b4b7a2550cd5930989b 168 SUPERFAMILY SSF51261 14 164 1.71E-54 T 29-03-2018 IPR011055 Duplicated hybrid motif CXR48_RS06420 d927b9a3f2e3cbaa435e4bcffb6450f7 526 Pfam PF07690 Major Facilitator Superfamily 55 276 2.0E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS06420 d927b9a3f2e3cbaa435e4bcffb6450f7 526 SUPERFAMILY SSF103473 1 198 4.84E-27 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS06420 d927b9a3f2e3cbaa435e4bcffb6450f7 526 SUPERFAMILY SSF103473 247 416 4.84E-27 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS06420 d927b9a3f2e3cbaa435e4bcffb6450f7 526 SUPERFAMILY SSF103473 443 473 4.84E-27 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS06420 d927b9a3f2e3cbaa435e4bcffb6450f7 526 Gene3D G3DSA:1.20.1250.20 1 197 9.3E-21 T 29-03-2018 CXR48_RS06420 d927b9a3f2e3cbaa435e4bcffb6450f7 526 Gene3D G3DSA:1.20.1250.20 256 482 1.8E-6 T 29-03-2018 CXR48_RS00895 354be1d8aef147071ef1032e167b8345 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 38.79 T 29-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 CXR48_RS00895 354be1d8aef147071ef1032e167b8345 265 Pfam PF02361 Cobalt transport protein 14 237 1.6E-63 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CXR48_RS14795 6c4232af1140b3f6b322686bb11efbd3 132 SUPERFAMILY SSF160515 4 126 1.16E-38 T 29-03-2018 CXR48_RS14795 6c4232af1140b3f6b322686bb11efbd3 132 Gene3D G3DSA:3.30.1330.30 4 123 5.8E-39 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CXR48_RS14795 6c4232af1140b3f6b322686bb11efbd3 132 Pfam PF07997 Protein of unknown function (DUF1694) 4 118 1.9E-35 T 29-03-2018 IPR012543 Protein of unknown function DUF1694 CXR48_RS14795 6c4232af1140b3f6b322686bb11efbd3 132 PIRSF PIRSF034303 1 131 1.8E-37 T 29-03-2018 IPR012543 Protein of unknown function DUF1694 CXR48_RS17260 651f9fd8319d4055b01401ee75b1913f 384 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 12 362 3.3E-116 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CXR48_RS17260 651f9fd8319d4055b01401ee75b1913f 384 Pfam PF01098 Cell cycle protein 12 365 1.8E-113 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CXR48_RS17260 651f9fd8319d4055b01401ee75b1913f 384 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 322 346 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CXR48_RS03450 538d3fa8d0ab070304963b0986f2d25c 156 Gene3D G3DSA:3.30.500.20 3 116 1.1E-34 T 29-03-2018 CXR48_RS03450 538d3fa8d0ab070304963b0986f2d25c 156 Pfam PF04634 Protein of unknown function, DUF600 6 151 4.7E-50 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03450 538d3fa8d0ab070304963b0986f2d25c 156 TIGRFAM TIGR01741 staph_tand_hypo: conserved hypothetical protein 2 155 9.6E-49 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03450 538d3fa8d0ab070304963b0986f2d25c 156 SUPERFAMILY SSF160424 3 155 5.36E-50 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 Gene3D G3DSA:3.90.1170.30 2 50 1.9E-15 T 29-03-2018 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 Gene3D G3DSA:4.10.320.10 104 177 5.9E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 Gene3D G3DSA:3.90.1170.30 51 97 0.0031 T 29-03-2018 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 SUPERFAMILY SSF52777 192 413 5.78E-85 T 29-03-2018 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 191 415 4.1E-85 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 Pfam PF00364 Biotin-requiring enzyme 5 77 3.8E-23 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 Gene3D G3DSA:3.30.559.10 178 418 4.5E-89 T 29-03-2018 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 SUPERFAMILY SSF47005 108 152 2.35E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 Pfam PF02817 e3 binding domain 114 148 3.0E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CXR48_RS11510 f48a92e39291226ffcf8881cbea53b86 420 SUPERFAMILY SSF51230 3 94 4.58E-26 T 29-03-2018 IPR011053 Single hybrid motif CXR48_RS12160 620ec6ca2b8606212c07c6349f9837a1 157 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 156 24.351 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CXR48_RS12160 620ec6ca2b8606212c07c6349f9837a1 157 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 122 132 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CXR48_RS12160 620ec6ca2b8606212c07c6349f9837a1 157 SUPERFAMILY SSF55486 3 156 4.39E-46 T 29-03-2018 CXR48_RS12160 620ec6ca2b8606212c07c6349f9837a1 157 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 153 4.4E-42 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CXR48_RS12160 620ec6ca2b8606212c07c6349f9837a1 157 Gene3D G3DSA:3.40.390.30 1 157 1.4E-52 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CXR48_RS12160 620ec6ca2b8606212c07c6349f9837a1 157 Pfam PF02130 Uncharacterized protein family UPF0054 15 152 3.6E-49 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CXR48_RS15045 29cc6e4dfb4b75bcf543adc947b0decf 108 PIRSF PIRSF010603 1 106 6.8E-50 T 29-03-2018 IPR009190 Protein of unknown function DUF1462 CXR48_RS15045 29cc6e4dfb4b75bcf543adc947b0decf 108 Pfam PF07315 Protein of unknown function (DUF1462) 9 100 1.2E-42 T 29-03-2018 IPR009190 Protein of unknown function DUF1462 CXR48_RS15045 29cc6e4dfb4b75bcf543adc947b0decf 108 SUPERFAMILY SSF52833 1 105 6.6E-45 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS15045 29cc6e4dfb4b75bcf543adc947b0decf 108 Gene3D G3DSA:3.40.30.30 3 102 9.9E-43 T 29-03-2018 CXR48_RS16815 a0351b5b056a5889bf11b6ba7ceaf58a 275 Pfam PF01061 ABC-2 type transporter 18 233 3.9E-28 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CXR48_RS19120 6929bf84415c956fbbb51df2eb16994c 218 SUPERFAMILY SSF102588 5 214 3.14E-38 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CXR48_RS19120 6929bf84415c956fbbb51df2eb16994c 218 Gene3D G3DSA:3.40.50.10320 2 218 5.5E-39 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CXR48_RS19120 6929bf84415c956fbbb51df2eb16994c 218 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 121 5.8E-17 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CXR48_RS04980 69b26c5d5024b41dc3cb4df3684d8b80 113 Gene3D G3DSA:1.10.3750.10 3 108 3.5E-40 T 29-03-2018 IPR015058 Protein of unknown function DUF1878 CXR48_RS04980 69b26c5d5024b41dc3cb4df3684d8b80 113 Pfam PF08963 Protein of unknown function (DUF1878) 1 110 3.2E-45 T 29-03-2018 IPR015058 Protein of unknown function DUF1878 CXR48_RS04980 69b26c5d5024b41dc3cb4df3684d8b80 113 SUPERFAMILY SSF109915 2 113 1.31E-48 T 29-03-2018 IPR015058 Protein of unknown function DUF1878 CXR48_RS04980 69b26c5d5024b41dc3cb4df3684d8b80 113 ProDom PD073069 YHAI 3D-STRUCTURE 10 113 7.0E-39 T 29-03-2018 IPR015058 Protein of unknown function DUF1878 CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 6.2E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 SMART SM00345 14 73 9.5E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.3E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.3E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 Pfam PF07702 UTRA domain 96 232 4.7E-31 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 SUPERFAMILY SSF64288 62 239 5.97E-40 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 Gene3D G3DSA:1.10.10.10 1 75 9.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 SUPERFAMILY SSF46785 2 84 5.96E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 SMART SM00866 95 233 4.7E-27 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CXR48_RS08390 253d811d7329a740a8b4d40293c6dec6 241 Gene3D G3DSA:3.40.1410.10 79 241 1.4E-30 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CXR48_RS17705 a1efaa8c2c7966d64fcc01d16d941511 72 SMART SM00421 8 65 0.0011 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS17705 a1efaa8c2c7966d64fcc01d16d941511 72 Pfam PF00196 Bacterial regulatory proteins, luxR family 15 63 3.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS17705 a1efaa8c2c7966d64fcc01d16d941511 72 SUPERFAMILY SSF46894 10 71 3.74E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS17705 a1efaa8c2c7966d64fcc01d16d941511 72 Gene3D G3DSA:1.10.10.10 2 72 1.0E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10005 5fdafd86dd6574f6fa0a3a30b7ea4247 193 Gene3D G3DSA:3.40.30.10 22 189 4.0E-35 T 29-03-2018 CXR48_RS10005 5fdafd86dd6574f6fa0a3a30b7ea4247 193 SUPERFAMILY SSF52833 28 189 5.69E-44 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS10005 5fdafd86dd6574f6fa0a3a30b7ea4247 193 Pfam PF02630 SCO1/SenC 5 172 1.1E-56 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS01585 23a6f978a203b8c35bde7ce05458abe6 282 Gene3D G3DSA:1.10.3720.10 80 279 5.3E-33 T 29-03-2018 CXR48_RS01585 23a6f978a203b8c35bde7ce05458abe6 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 265 8.9E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS01585 23a6f978a203b8c35bde7ce05458abe6 282 SUPERFAMILY SSF161098 86 269 2.35E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15795 c1cf2b6f67474fe36fd39d87edc777d0 270 SUPERFAMILY SSF53850 35 263 9.83E-49 T 29-03-2018 CXR48_RS15795 c1cf2b6f67474fe36fd39d87edc777d0 270 Gene3D G3DSA:3.40.190.10 160 270 5.2E-13 T 29-03-2018 CXR48_RS15795 c1cf2b6f67474fe36fd39d87edc777d0 270 SMART SM00062 35 262 5.9E-66 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS15795 c1cf2b6f67474fe36fd39d87edc777d0 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 260 8.5E-47 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS15795 c1cf2b6f67474fe36fd39d87edc777d0 270 Gene3D G3DSA:3.40.190.10 33 159 1.2E-25 T 29-03-2018 CXR48_RS13655 cb4d57b2236d234bd67a63e5fc5b9895 563 Gene3D G3DSA:1.20.120.340 347 499 1.1E-4 T 29-03-2018 CXR48_RS13655 cb4d57b2236d234bd67a63e5fc5b9895 563 SUPERFAMILY SSF109775 346 495 4.84E-5 T 29-03-2018 CXR48_RS13655 cb4d57b2236d234bd67a63e5fc5b9895 563 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 1 563 22.516 T 29-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CXR48_RS13655 cb4d57b2236d234bd67a63e5fc5b9895 563 Gene3D G3DSA:1.20.58.90 31 156 6.8E-6 T 29-03-2018 CXR48_RS13655 cb4d57b2236d234bd67a63e5fc5b9895 563 Pfam PF06160 Septation ring formation regulator, EzrA 4 558 2.8E-170 T 29-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 Gene3D G3DSA:3.40.190.10 92 169 8.6E-14 T 29-03-2018 CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 Pfam PF03466 LysR substrate binding domain 87 281 3.3E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 Gene3D G3DSA:1.10.10.10 1 91 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 SUPERFAMILY SSF53850 88 282 9.37E-29 T 29-03-2018 CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 SUPERFAMILY SSF46785 1 111 6.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 62 2.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS16310 e2e12c38ad116e28acb020a1634dc4ea 286 Gene3D G3DSA:3.40.190.10 170 249 1.3E-9 T 29-03-2018 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 SUPERFAMILY SSF55124 13 145 1.05E-32 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 Gene3D G3DSA:3.30.413.10 77 138 0.01 T 29-03-2018 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 479 495 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 353 417 1.0E-12 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 75 136 1.4E-13 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 8 571 58.324 T 29-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 PRINTS PR00397 Sirohaem Fe-binding site signature 479 497 1.6E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 PRINTS PR00397 Sirohaem Fe-binding site signature 431 449 1.6E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 SUPERFAMILY SSF56014 146 344 1.83E-57 T 29-03-2018 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 430 559 2.2E-4 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 170 330 5.1E-47 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 Gene3D G3DSA:3.30.413.10 427 565 1.4E-28 T 29-03-2018 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 SUPERFAMILY SSF56014 429 561 1.31E-36 T 29-03-2018 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 Gene3D G3DSA:3.30.413.10 139 346 1.3E-53 T 29-03-2018 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 17 560 1.3E-285 T 29-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS15695 717ac1151dd07cedcb51342847f4bfd2 571 SUPERFAMILY SSF55124 346 422 1.21E-21 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CXR48_RS09990 25639d63f34828e22127bd4bee61273c 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 4.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS09990 25639d63f34828e22127bd4bee61273c 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 4.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS09990 25639d63f34828e22127bd4bee61273c 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 4.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS09990 25639d63f34828e22127bd4bee61273c 141 SMART SM00347 27 127 9.6E-32 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS09990 25639d63f34828e22127bd4bee61273c 141 SUPERFAMILY SSF46785 10 137 3.78E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09990 25639d63f34828e22127bd4bee61273c 141 Gene3D G3DSA:1.10.10.10 1 141 3.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09990 25639d63f34828e22127bd4bee61273c 141 Pfam PF01047 MarR family 34 91 2.4E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS02225 7a60702315b844e9a828918d3f753a38 148 SUPERFAMILY SSF55811 4 121 1.62E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CXR48_RS02225 7a60702315b844e9a828918d3f753a38 148 Pfam PF00293 NUDIX domain 4 115 5.8E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CXR48_RS02225 7a60702315b844e9a828918d3f753a38 148 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CXR48_RS02225 7a60702315b844e9a828918d3f753a38 148 PRINTS PR00502 NUDIX hydrolase family signature 27 41 6.5E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS02225 7a60702315b844e9a828918d3f753a38 148 PRINTS PR00502 NUDIX hydrolase family signature 41 56 6.5E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS02225 7a60702315b844e9a828918d3f753a38 148 Gene3D G3DSA:3.90.79.10 1 143 1.1E-25 T 29-03-2018 CXR48_RS08335 a8d62768ab02187745085829d592b889 411 Gene3D G3DSA:3.30.830.10 1 215 1.0E-62 T 29-03-2018 CXR48_RS08335 a8d62768ab02187745085829d592b889 411 SUPERFAMILY SSF63411 225 401 2.67E-45 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CXR48_RS08335 a8d62768ab02187745085829d592b889 411 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CXR48_RS08335 a8d62768ab02187745085829d592b889 411 Gene3D G3DSA:3.30.830.10 237 411 6.2E-42 T 29-03-2018 CXR48_RS08335 a8d62768ab02187745085829d592b889 411 Pfam PF05193 Peptidase M16 inactive domain 166 338 2.0E-37 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CXR48_RS08335 a8d62768ab02187745085829d592b889 411 SUPERFAMILY SSF63411 3 204 1.4E-62 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CXR48_RS08335 a8d62768ab02187745085829d592b889 411 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 1.6E-50 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CXR48_RS16225 5403a57bf0273a053c3bf3eb710dc919 176 Gene3D G3DSA:3.40.430.10 2 175 6.1E-38 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CXR48_RS16225 5403a57bf0273a053c3bf3eb710dc919 176 SUPERFAMILY SSF53597 5 168 1.7E-35 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CXR48_RS16225 5403a57bf0273a053c3bf3eb710dc919 176 Pfam PF01872 RibD C-terminal domain 6 165 6.4E-19 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CXR48_RS10645 845e071ec83e2a655ff707812a8fee8b 237 SUPERFAMILY SSF102588 6 227 2.22E-55 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CXR48_RS10645 845e071ec83e2a655ff707812a8fee8b 237 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 124 1.9E-22 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CXR48_RS10645 845e071ec83e2a655ff707812a8fee8b 237 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 5 225 1.5E-96 T 29-03-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 CXR48_RS10645 845e071ec83e2a655ff707812a8fee8b 237 Gene3D G3DSA:3.40.50.10320 3 233 6.7E-53 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CXR48_RS10705 ae8890e1923616e2011b3c37cf6500eb 179 Hamap MF_00760 UPF0302 protein . 2 178 33.097 T 29-03-2018 IPR011188 Uncharacterised protein family UPF0302 CXR48_RS10705 ae8890e1923616e2011b3c37cf6500eb 179 Pfam PF08864 UPF0302 domain 9 112 5.7E-47 T 29-03-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal CXR48_RS10705 ae8890e1923616e2011b3c37cf6500eb 179 SMART SM00914 139 175 7.1E-15 T 29-03-2018 IPR014957 IDEAL domain CXR48_RS10705 ae8890e1923616e2011b3c37cf6500eb 179 Pfam PF08858 IDEAL domain 139 175 2.5E-14 T 29-03-2018 IPR014957 IDEAL domain CXR48_RS10705 ae8890e1923616e2011b3c37cf6500eb 179 PIRSF PIRSF007165 1 179 5.5E-83 T 29-03-2018 IPR011188 Uncharacterised protein family UPF0302 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 86 150 1.8E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 267 320 1.8E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 340 373 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 135 168 77.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 238 271 18.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 374 407 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 171 204 1.4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 272 305 83.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 194 266 7.2E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 Pfam PF14559 Tetratricopeptide repeat 47 109 6.2E-7 T 29-03-2018 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 Pfam PF13432 Tetratricopeptide repeat 139 199 5.8E-5 T 29-03-2018 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 SUPERFAMILY SSF48452 39 199 3.64E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 SUPERFAMILY SSF48452 205 407 1.69E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 1 85 2.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 151 193 2.4E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 Pfam PF13429 Tetratricopeptide repeat 239 401 1.2E-8 T 29-03-2018 CXR48_RS10710 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 321 421 3.0E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS08160 d8cbe0915f0b13a11c89ff0ff624064c 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 6.5E-25 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CXR48_RS08160 d8cbe0915f0b13a11c89ff0ff624064c 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 6.5E-25 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CXR48_RS08160 d8cbe0915f0b13a11c89ff0ff624064c 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 6.5E-25 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CXR48_RS08160 d8cbe0915f0b13a11c89ff0ff624064c 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 3 87 1.4E-33 T 29-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CXR48_RS08160 d8cbe0915f0b13a11c89ff0ff624064c 89 PIRSF PIRSF004669 1 89 1.2E-34 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CXR48_RS08160 d8cbe0915f0b13a11c89ff0ff624064c 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 5.8E-31 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 23.92 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 3.3E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 3.3E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 3.3E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 3.2E-35 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 Gene3D G3DSA:2.40.50.140 7 84 1.5E-31 T 29-03-2018 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 Pfam PF00366 Ribosomal protein S17 12 79 3.6E-32 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 1.0E-33 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00780 e6040d6c15c18e80ba6ef08241994211 87 SUPERFAMILY SSF50249 7 84 9.85E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS03300 515141454642a7335036546bc248ee03 476 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 456 47.288 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CXR48_RS03300 515141454642a7335036546bc248ee03 476 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 457 6.2E-174 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CXR48_RS03300 515141454642a7335036546bc248ee03 476 SUPERFAMILY SSF53271 247 469 2.88E-76 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS03300 515141454642a7335036546bc248ee03 476 Gene3D G3DSA:3.40.50.2020 239 438 3.4E-34 T 29-03-2018 CXR48_RS03300 515141454642a7335036546bc248ee03 476 Pfam PF00156 Phosphoribosyl transferase domain 283 382 4.7E-7 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CXR48_RS03300 515141454642a7335036546bc248ee03 476 Pfam PF13522 Glutamine amidotransferase domain 69 205 6.1E-22 T 29-03-2018 CXR48_RS03300 515141454642a7335036546bc248ee03 476 PIRSF PIRSF000485 8 473 4.4E-191 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CXR48_RS03300 515141454642a7335036546bc248ee03 476 SUPERFAMILY SSF56235 12 237 4.8E-70 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS03300 515141454642a7335036546bc248ee03 476 Gene3D G3DSA:3.60.20.10 12 238 2.9E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS13480 53e4468fe01b6b21b29ac68482b19dde 57 Pfam PF01471 Putative peptidoglycan binding domain 19 46 3.1E-7 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS13480 53e4468fe01b6b21b29ac68482b19dde 57 Gene3D G3DSA:1.10.101.10 8 52 2.6E-6 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS13480 53e4468fe01b6b21b29ac68482b19dde 57 SUPERFAMILY SSF47090 15 47 1.4E-7 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS05760 679a8b4cb89704f7b10fd234e808936e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05760 679a8b4cb89704f7b10fd234e808936e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05760 679a8b4cb89704f7b10fd234e808936e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05760 679a8b4cb89704f7b10fd234e808936e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS05760 679a8b4cb89704f7b10fd234e808936e 258 Gene3D G3DSA:3.40.50.720 1 258 3.8E-47 T 29-03-2018 CXR48_RS05760 679a8b4cb89704f7b10fd234e808936e 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 4.8E-88 T 29-03-2018 CXR48_RS05760 679a8b4cb89704f7b10fd234e808936e 258 SUPERFAMILY SSF51735 6 255 7.21E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS05760 679a8b4cb89704f7b10fd234e808936e 258 PIRSF PIRSF000094 2 258 3.1E-105 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 Pfam PF00361 Proton-conducting membrane transporter 130 418 2.3E-67 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 Pfam PF13244 Domain of unknown function (DUF4040) 635 700 3.8E-22 T 29-03-2018 IPR025383 Domain of unknown function DUF4040 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 259 281 4.5E-5 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 79 99 4.5E-5 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 365 387 4.5E-5 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 63 116 2.3E-10 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 4 796 0.0 T 29-03-2018 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 6.2E-43 T 29-03-2018 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 153 174 6.2E-43 T 29-03-2018 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 6.2E-43 T 29-03-2018 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 6.2E-43 T 29-03-2018 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 6.2E-43 T 29-03-2018 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 106 126 6.2E-43 T 29-03-2018 CXR48_RS14710 fd1bbe0d9340aa184c59e408b5d73e8d 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 6.2E-43 T 29-03-2018 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 Gene3D G3DSA:3.40.1190.10 103 309 3.5E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 SUPERFAMILY SSF51984 10 101 8.37E-16 T 29-03-2018 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 SUPERFAMILY SSF53244 311 450 2.84E-41 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 376 5.6E-8 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 Pfam PF08245 Mur ligase middle domain 118 292 4.0E-29 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 448 1.4E-148 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 SUPERFAMILY SSF53623 104 309 3.66E-51 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 Gene3D G3DSA:3.40.50.720 2 102 5.0E-14 T 29-03-2018 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 450 35.872 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS07580 46b4c54440ae774d3f8dfa13f45917ff 451 Gene3D G3DSA:3.90.190.20 316 449 2.3E-34 T 29-03-2018 CXR48_RS18620 d8a6131428fc24f357cfd12059bb87f9 313 Pfam PF12802 MarR family 21 53 8.4E-7 T 29-03-2018 CXR48_RS18620 d8a6131428fc24f357cfd12059bb87f9 313 SUPERFAMILY SSF100950 56 311 3.72E-75 T 29-03-2018 CXR48_RS18620 d8a6131428fc24f357cfd12059bb87f9 313 Pfam PF04198 Putative sugar-binding domain 57 310 1.4E-82 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CXR48_RS18620 d8a6131428fc24f357cfd12059bb87f9 313 SUPERFAMILY SSF88659 14 47 1.37E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS18620 d8a6131428fc24f357cfd12059bb87f9 313 Gene3D G3DSA:1.10.10.60 1 51 4.0E-16 T 29-03-2018 CXR48_RS18620 d8a6131428fc24f357cfd12059bb87f9 313 Gene3D G3DSA:3.40.50.1360 52 311 1.2E-44 T 29-03-2018 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 Gene3D G3DSA:3.30.70.1560 143 213 1.6E-20 T 29-03-2018 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 Pfam PF00849 RNA pseudouridylate synthase 62 195 4.0E-18 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 Gene3D G3DSA:3.10.290.10 1 69 1.2E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 Pfam PF01479 S4 domain 1 44 5.2E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 SUPERFAMILY SSF55174 1 59 6.87E-12 T 29-03-2018 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 Gene3D G3DSA:3.30.70.580 70 142 4.4E-16 T 29-03-2018 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 SUPERFAMILY SSF55120 48 234 7.36E-41 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 SMART SM00363 1 59 2.1E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS13935 a7939e4f879af4509051af39ac020920 239 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 228 1.5E-46 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CXR48_RS00760 c2e08b099ec161f5bc916bfefafbd392 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.684 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00760 c2e08b099ec161f5bc916bfefafbd392 113 SUPERFAMILY SSF54843 1 112 2.09E-44 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00760 c2e08b099ec161f5bc916bfefafbd392 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 2.8E-37 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00760 c2e08b099ec161f5bc916bfefafbd392 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00760 c2e08b099ec161f5bc916bfefafbd392 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.6E-54 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00760 c2e08b099ec161f5bc916bfefafbd392 113 Gene3D G3DSA:3.90.470.10 1 113 1.6E-44 T 29-03-2018 CXR48_RS10085 3cbadbd82ff4720a286ae13eba8c55ad 380 Gene3D G3DSA:3.40.50.2000 182 362 3.6E-31 T 29-03-2018 CXR48_RS10085 3cbadbd82ff4720a286ae13eba8c55ad 380 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 18 178 1.4E-46 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CXR48_RS10085 3cbadbd82ff4720a286ae13eba8c55ad 380 Hamap MF_01280 Processive diacylglycerol beta-glucosyltransferase [ugtP]. 1 380 54.403 T 29-03-2018 IPR023589 Processive diacylglycerol beta-glucosyltransferase GO:0047228 KEGG: 00561+2.4.1.315|MetaCyc: PWY-6778|MetaCyc: PWY-7817 CXR48_RS10085 3cbadbd82ff4720a286ae13eba8c55ad 380 SUPERFAMILY SSF53756 5 365 5.11E-44 T 29-03-2018 CXR48_RS10085 3cbadbd82ff4720a286ae13eba8c55ad 380 Pfam PF00534 Glycosyl transferases group 1 183 349 3.6E-18 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CXR48_RS10085 3cbadbd82ff4720a286ae13eba8c55ad 380 Gene3D G3DSA:3.40.50.2000 1 181 2.6E-8 T 29-03-2018 CXR48_RS18565 f48313e891d9d6c5f2a37a25d6cd8174 129 Gene3D G3DSA:3.90.79.10 2 129 1.9E-28 T 29-03-2018 CXR48_RS18565 f48313e891d9d6c5f2a37a25d6cd8174 129 SUPERFAMILY SSF55811 2 127 2.71E-32 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CXR48_RS18565 f48313e891d9d6c5f2a37a25d6cd8174 129 Pfam PF00293 NUDIX domain 7 121 2.4E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CXR48_RS18565 f48313e891d9d6c5f2a37a25d6cd8174 129 PRINTS PR00502 NUDIX hydrolase family signature 48 63 6.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS18565 f48313e891d9d6c5f2a37a25d6cd8174 129 PRINTS PR00502 NUDIX hydrolase family signature 34 48 6.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS00155 ea39e385f919a25621864b435ec4b313 87 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 11 83 1.6E-18 T 29-03-2018 IPR010001 SigmaK-factor processing regulatory BofA CXR48_RS00155 ea39e385f919a25621864b435ec4b313 87 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 86 3.2E-27 T 29-03-2018 IPR010001 SigmaK-factor processing regulatory BofA CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 PRINTS PR00412 Epoxide hydrolase signature 113 126 8.0E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 PRINTS PR00412 Epoxide hydrolase signature 53 68 8.0E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 PRINTS PR00412 Epoxide hydrolase signature 261 283 8.0E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 PRINTS PR00412 Epoxide hydrolase signature 33 51 8.0E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 PRINTS PR00412 Epoxide hydrolase signature 99 112 8.0E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 Gene3D G3DSA:3.40.50.1820 1 286 5.7E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 SUPERFAMILY SSF53474 1 286 4.09E-72 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 4.2E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 4.2E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 4.2E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS04155 479fbfe671dada922c367e373ec82ebb 286 Pfam PF00561 alpha/beta hydrolase fold 30 273 3.0E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS09495 1ce3f0f4811d5df331d6e8fa6a2be12a 208 Gene3D G3DSA:3.40.50.360 3 208 1.2E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS09495 1ce3f0f4811d5df331d6e8fa6a2be12a 208 Pfam PF02525 Flavodoxin-like fold 3 203 3.7E-43 T 29-03-2018 IPR003680 Flavodoxin-like fold CXR48_RS09495 1ce3f0f4811d5df331d6e8fa6a2be12a 208 SUPERFAMILY SSF52218 1 208 1.41E-48 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS09495 1ce3f0f4811d5df331d6e8fa6a2be12a 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 28.898 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CXR48_RS00270 dbe50e335b4126deb52a10a4497bd3f7 187 Pfam PF13662 Toprim domain 4 71 1.4E-6 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS00270 dbe50e335b4126deb52a10a4497bd3f7 187 SUPERFAMILY SSF110455 1 115 1.86E-35 T 29-03-2018 CXR48_RS00270 dbe50e335b4126deb52a10a4497bd3f7 187 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 178 31.095 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CXR48_RS00270 dbe50e335b4126deb52a10a4497bd3f7 187 Gene3D G3DSA:3.40.1360.20 1 125 2.4E-23 T 29-03-2018 CXR48_RS00270 dbe50e335b4126deb52a10a4497bd3f7 187 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 177 2.4E-75 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CXR48_RS00270 dbe50e335b4126deb52a10a4497bd3f7 187 SMART SM00493 4 77 1.8E-8 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS00270 dbe50e335b4126deb52a10a4497bd3f7 187 Pfam PF13331 Domain of unknown function (DUF4093) 93 176 2.4E-26 T 29-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CXR48_RS10925 534f643fca0e272fc7dc3c37d5370cba 352 Pfam PF14493 Helix-turn-helix domain 256 344 2.7E-19 T 29-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CXR48_RS10925 534f643fca0e272fc7dc3c37d5370cba 352 PIRSF PIRSF021350 4 352 4.9E-104 T 29-03-2018 IPR008308 Uncharacterised conserved protein UCP021350 CXR48_RS10925 534f643fca0e272fc7dc3c37d5370cba 352 Gene3D G3DSA:1.10.10.10 250 347 0.0015 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10635 0fcd0c6a7d4d6bed9b3890f055727125 396 Gene3D G3DSA:3.30.460.10 3 141 2.1E-47 T 29-03-2018 CXR48_RS10635 0fcd0c6a7d4d6bed9b3890f055727125 396 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 169 227 8.5E-13 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CXR48_RS10635 0fcd0c6a7d4d6bed9b3890f055727125 396 SUPERFAMILY SSF81301 7 138 5.89E-41 T 29-03-2018 CXR48_RS10635 0fcd0c6a7d4d6bed9b3890f055727125 396 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 245 389 3.3E-32 T 29-03-2018 IPR032810 CCA-adding enzyme, C-terminal CXR48_RS10635 0fcd0c6a7d4d6bed9b3890f055727125 396 Pfam PF01743 Poly A polymerase head domain 22 142 7.0E-39 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CXR48_RS10635 0fcd0c6a7d4d6bed9b3890f055727125 396 Gene3D G3DSA:1.10.3090.10 142 393 8.3E-40 T 29-03-2018 CXR48_RS10635 0fcd0c6a7d4d6bed9b3890f055727125 396 SUPERFAMILY SSF81891 140 393 2.49E-50 T 29-03-2018 CXR48_RS10635 0fcd0c6a7d4d6bed9b3890f055727125 396 Hamap MF_01263 CCA-adding enzyme [cca]. 2 394 39.289 T 29-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 CXR48_RS04860 990ac9e81bb12d65b11ccd851a3df3e9 363 SUPERFAMILY SSF56059 107 330 1.4E-17 T 29-03-2018 CXR48_RS04860 990ac9e81bb12d65b11ccd851a3df3e9 363 Gene3D G3DSA:3.30.470.20 103 341 6.7E-16 T 29-03-2018 CXR48_RS04860 990ac9e81bb12d65b11ccd851a3df3e9 363 Pfam PF14398 YheC/D like ATP-grasp 98 344 1.2E-60 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CXR48_RS18915 7e2f42df2882d4eb8606695ab5be6baa 394 Gene3D G3DSA:2.130.10.150 24 369 1.4E-5 T 29-03-2018 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 Gene3D G3DSA:1.10.520.20 3 106 6.0E-25 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 SUPERFAMILY SSF47928 4 105 1.31E-24 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 85 99 2.6E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 74 85 2.6E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 136 151 2.6E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 6 25 2.6E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 151 169 2.6E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 19.826 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 176 9.3E-48 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 2.3E-58 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17415 666f8a03bb65fa27cd39de23c6cc88c3 181 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 29-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS19320 df66bc20a90aacd0d4923f43f0817c2f 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 124 5.5E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS19320 df66bc20a90aacd0d4923f43f0817c2f 126 Gene3D G3DSA:3.10.180.10 1 126 1.6E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS19320 df66bc20a90aacd0d4923f43f0817c2f 126 SUPERFAMILY SSF54593 1 125 1.1E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS16180 2c0afe61cc8b7e394a9e626f2b6f24cf 378 Gene3D G3DSA:3.40.50.2000 1 189 6.8E-15 T 29-03-2018 CXR48_RS16180 2c0afe61cc8b7e394a9e626f2b6f24cf 378 Gene3D G3DSA:3.40.50.2000 190 356 3.4E-30 T 29-03-2018 CXR48_RS16180 2c0afe61cc8b7e394a9e626f2b6f24cf 378 Pfam PF00534 Glycosyl transferases group 1 187 307 1.1E-26 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CXR48_RS16180 2c0afe61cc8b7e394a9e626f2b6f24cf 378 SUPERFAMILY SSF53756 7 310 1.26E-56 T 29-03-2018 CXR48_RS16180 2c0afe61cc8b7e394a9e626f2b6f24cf 378 Pfam PF13439 Glycosyltransferase Family 4 18 178 9.8E-16 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CXR48_RS12050 012b61e6f6fe8a071e399f89b459640c 136 Pfam PF01475 Ferric uptake regulator family 12 129 1.7E-29 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CXR48_RS12050 012b61e6f6fe8a071e399f89b459640c 136 SUPERFAMILY SSF46785 5 133 2.59E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12050 012b61e6f6fe8a071e399f89b459640c 136 Gene3D G3DSA:1.10.10.10 6 92 3.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18275 b12f20908fc71c1e90529c249b39b482 102 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 93 1.4E-37 T 29-03-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CXR48_RS18275 b12f20908fc71c1e90529c249b39b482 102 SUPERFAMILY SSF52794 1 98 2.62E-35 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS18275 b12f20908fc71c1e90529c249b39b482 102 Gene3D G3DSA:3.40.50.2300 1 102 1.1E-36 T 29-03-2018 CXR48_RS18275 b12f20908fc71c1e90529c249b39b482 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 8.2E-22 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS02030 c717a2eee33f4cbd0e2414418e3f5916 287 Pfam PF06800 Sugar transport protein 4 282 9.2E-111 T 29-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 CXR48_RS02030 c717a2eee33f4cbd0e2414418e3f5916 287 SUPERFAMILY SSF103481 37 138 1.96E-8 T 29-03-2018 CXR48_RS02030 c717a2eee33f4cbd0e2414418e3f5916 287 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 1 284 1.9E-115 T 29-03-2018 CXR48_RS18740 6ef4bc671cc3a7b0b93b1ea30f08b21e 310 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 140 157 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS18740 6ef4bc671cc3a7b0b93b1ea30f08b21e 310 Gene3D G3DSA:3.20.20.100 1 310 6.5E-101 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS18740 6ef4bc671cc3a7b0b93b1ea30f08b21e 310 SUPERFAMILY SSF51430 1 309 9.04E-100 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS18740 6ef4bc671cc3a7b0b93b1ea30f08b21e 310 Pfam PF00248 Aldo/keto reductase family 15 308 3.2E-77 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS18740 6ef4bc671cc3a7b0b93b1ea30f08b21e 310 PRINTS PR00069 Aldo-keto reductase signature 44 68 1.7E-13 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS18740 6ef4bc671cc3a7b0b93b1ea30f08b21e 310 PRINTS PR00069 Aldo-keto reductase signature 140 157 1.7E-13 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS18740 6ef4bc671cc3a7b0b93b1ea30f08b21e 310 PRINTS PR00069 Aldo-keto reductase signature 109 127 1.7E-13 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 Gene3D G3DSA:2.20.25.90 1 62 1.1E-17 T 29-03-2018 CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 Pfam PF01568 Molydopterin dinucleotide binding domain 563 650 8.1E-13 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 3 53 7.6E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 Gene3D G3DSA:3.40.50.740 63 235 3.3E-28 T 29-03-2018 CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 SMART SM00926 2 56 1.7E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 Gene3D G3DSA:3.40.50.740 249 509 1.1E-40 T 29-03-2018 CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 SUPERFAMILY SSF50692 512 666 1.56E-24 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 Pfam PF00384 Molybdopterin oxidoreductase 60 461 8.6E-54 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 Gene3D G3DSA:2.40.40.20 528 666 2.5E-20 T 29-03-2018 CXR48_RS19365 442737822579d7de3c2fe9434af65a83 667 SUPERFAMILY SSF53706 3 545 3.53E-145 T 29-03-2018 CXR48_RS17490 cb7fdf285cbdbb51bff21b96cd1f84c1 92 Pfam PF17247 Family of unknown function (DUF5316) 29 89 2.1E-13 T 29-03-2018 IPR035167 Protein of unknown function DUF5316 CXR48_RS10360 04994931b62d81b4a197fb9852c26be7 171 Gene3D G3DSA:1.10.10.10 67 167 1.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10360 04994931b62d81b4a197fb9852c26be7 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 162 2.6E-14 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS10360 04994931b62d81b4a197fb9852c26be7 171 Pfam PF08281 Sigma-70, region 4 107 159 2.8E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS10360 04994931b62d81b4a197fb9852c26be7 171 SUPERFAMILY SSF88659 94 163 1.85E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS00280 1b0962ff5ab6826e22e71da2bb591770 291 PIRSF PIRSF011575 2 291 1.1E-137 T 29-03-2018 IPR008764 Peptidase U57, YabG CXR48_RS00280 1b0962ff5ab6826e22e71da2bb591770 291 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 4 283 6.0E-154 T 29-03-2018 IPR008764 Peptidase U57, YabG CXR48_RS00280 1b0962ff5ab6826e22e71da2bb591770 291 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 4 287 3.1E-143 T 29-03-2018 IPR008764 Peptidase U57, YabG CXR48_RS00280 1b0962ff5ab6826e22e71da2bb591770 291 Pfam PF05582 YabG peptidase U57 4 286 1.3E-118 T 29-03-2018 IPR008764 Peptidase U57, YabG CXR48_RS10220 489644958e92f7ae654744cc5b81ea57 386 Pfam PF01471 Putative peptidoglycan binding domain 319 381 6.8E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS10220 489644958e92f7ae654744cc5b81ea57 386 SMART SM00644 14 184 2.5E-27 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS10220 489644958e92f7ae654744cc5b81ea57 386 Gene3D G3DSA:2.30.30.410 196 295 9.6E-9 T 29-03-2018 CXR48_RS10220 489644958e92f7ae654744cc5b81ea57 386 SUPERFAMILY SSF55846 7 185 5.37E-32 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS10220 489644958e92f7ae654744cc5b81ea57 386 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 23 168 2.5E-20 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS10220 489644958e92f7ae654744cc5b81ea57 386 Gene3D G3DSA:1.10.101.10 300 386 2.3E-20 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS10220 489644958e92f7ae654744cc5b81ea57 386 Gene3D G3DSA:3.40.80.10 6 195 2.6E-31 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CXR48_RS10220 489644958e92f7ae654744cc5b81ea57 386 SUPERFAMILY SSF47090 311 381 2.62E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS12290 6faa8f1f5ef24e4ae5ac31a26e46fefe 783 Pfam PF13567 Domain of unknown function (DUF4131) 25 171 1.1E-20 T 29-03-2018 IPR025405 Domain of unknown function DUF4131 CXR48_RS12290 6faa8f1f5ef24e4ae5ac31a26e46fefe 783 Pfam PF00753 Metallo-beta-lactamase superfamily 508 719 1.1E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS12290 6faa8f1f5ef24e4ae5ac31a26e46fefe 783 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 229 399 1.9E-41 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CXR48_RS12290 6faa8f1f5ef24e4ae5ac31a26e46fefe 783 Gene3D G3DSA:3.60.15.10 501 745 7.3E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS12290 6faa8f1f5ef24e4ae5ac31a26e46fefe 783 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 69 749 4.3E-194 T 29-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CXR48_RS12290 6faa8f1f5ef24e4ae5ac31a26e46fefe 783 Pfam PF03772 Competence protein 208 468 2.5E-61 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CXR48_RS12290 6faa8f1f5ef24e4ae5ac31a26e46fefe 783 SMART SM00849 509 720 1.1E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS12290 6faa8f1f5ef24e4ae5ac31a26e46fefe 783 SUPERFAMILY SSF56281 504 755 4.76E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS06280 9e8b1a07c7fb5a4f39563e5086ae799e 465 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 203 350 3.0E-34 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain CXR48_RS06280 9e8b1a07c7fb5a4f39563e5086ae799e 465 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 332 464 5.0E-58 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain CXR48_RS06280 9e8b1a07c7fb5a4f39563e5086ae799e 465 Pfam PF17482 Phage tail sheath C-terminal domain 357 464 6.9E-25 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain CXR48_RS06280 9e8b1a07c7fb5a4f39563e5086ae799e 465 Pfam PF17481 Phage tail sheath protein beta-sandwich domain 102 198 5.8E-10 T 29-03-2018 IPR035326 Phage tail sheath protein, beta-sandwich domain CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 83 7.0E-19 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 SUPERFAMILY SSF110836 1 85 3.4E-22 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 Pfam PF13646 HEAT repeats 267 343 2.7E-12 T 29-03-2018 CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 SUPERFAMILY SSF48371 183 373 3.09E-34 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 SMART SM00932 4 90 1.1E-28 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 Gene3D G3DSA:1.25.40.70 292 357 4.7E-10 T 29-03-2018 CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 Gene3D G3DSA:1.25.40.70 181 291 1.0E-16 T 29-03-2018 CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 Pfam PF13769 Virulence factor 108 187 6.4E-30 T 29-03-2018 IPR025989 Virulence factor domain CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 SMART SM00567 E-Z type HEAT repeats 219 246 1000.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 SMART SM00567 E-Z type HEAT repeats 310 339 3.0E-4 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 SMART SM00567 E-Z type HEAT repeats 248 277 0.028 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 SMART SM00567 E-Z type HEAT repeats 279 308 0.072 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CXR48_RS10065 c0caea0345ca6e210a0fd759909e72e1 376 Gene3D G3DSA:3.30.1370.70 2 89 1.3E-19 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CXR48_RS18000 255a234ae0e2f47fc8c789dda4d3c097 479 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 394 476 7.8E-9 T 29-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CXR48_RS18000 255a234ae0e2f47fc8c789dda4d3c097 479 Gene3D G3DSA:2.115.10.20 38 358 6.5E-99 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS18000 255a234ae0e2f47fc8c789dda4d3c097 479 SUPERFAMILY SSF49899 341 478 4.91E-16 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CXR48_RS18000 255a234ae0e2f47fc8c789dda4d3c097 479 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 33 338 1.1E-101 T 29-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CXR48_RS18000 255a234ae0e2f47fc8c789dda4d3c097 479 SMART SM00640 33 444 7.7E-135 T 29-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CXR48_RS18000 255a234ae0e2f47fc8c789dda4d3c097 479 SUPERFAMILY SSF75005 24 338 2.04E-109 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS18000 255a234ae0e2f47fc8c789dda4d3c097 479 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 17 454 1.5E-171 T 29-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CXR48_RS18000 255a234ae0e2f47fc8c789dda4d3c097 479 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 33 46 - T 29-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CXR48_RS18000 255a234ae0e2f47fc8c789dda4d3c097 479 Gene3D G3DSA:2.60.120.560 359 478 2.1E-11 T 29-03-2018 CXR48_RS17360 568eb46366340b3eea265798d2a83006 229 Pfam PF00092 von Willebrand factor type A domain 35 217 5.2E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS17360 568eb46366340b3eea265798d2a83006 229 SMART SM00327 33 226 4.6E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS17360 568eb46366340b3eea265798d2a83006 229 Gene3D G3DSA:3.40.50.410 25 228 1.6E-31 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS17360 568eb46366340b3eea265798d2a83006 229 SUPERFAMILY SSF53300 22 223 4.77E-25 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS13910 cc234422ac0342eb09aa8fcfdae14cc4 434 Pfam PF00860 Permease family 14 394 7.9E-76 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS13910 cc234422ac0342eb09aa8fcfdae14cc4 434 PIRSF PIRSF005353 1 433 1.4E-170 T 29-03-2018 IPR026033 Purine permease PbuG-like CXR48_RS15095 56ae57ceaeec766ae592e500b7dd000c 91 PIRSF PIRSF012565 1 91 8.7E-50 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 CXR48_RS15095 56ae57ceaeec766ae592e500b7dd000c 91 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 7.9E-39 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 CXR48_RS03750 41c999a672578c11489e9ff08707700e 219 Pfam PF03473 MOSC domain 52 158 6.6E-24 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CXR48_RS03750 41c999a672578c11489e9ff08707700e 219 Gene3D G3DSA:2.40.33.20 1 218 1.7E-47 T 29-03-2018 CXR48_RS03750 41c999a672578c11489e9ff08707700e 219 SUPERFAMILY SSF50800 3 215 6.28E-69 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CXR48_RS03750 41c999a672578c11489e9ff08707700e 219 Pfam PF03475 3-alpha domain 173 214 2.6E-9 T 29-03-2018 IPR005163 3-alpha domain CXR48_RS17965 5340f1b19b292bddb21dfde56cffe07d 227 SMART SM00987 50 210 1.3E-34 T 29-03-2018 CXR48_RS17965 5340f1b19b292bddb21dfde56cffe07d 227 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CXR48_RS17965 5340f1b19b292bddb21dfde56cffe07d 227 Pfam PF03167 Uracil DNA glycosylase superfamily 52 208 4.9E-24 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CXR48_RS17965 5340f1b19b292bddb21dfde56cffe07d 227 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 214 5.8E-85 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CXR48_RS17965 5340f1b19b292bddb21dfde56cffe07d 227 SUPERFAMILY SSF52141 4 222 5.01E-94 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CXR48_RS17965 5340f1b19b292bddb21dfde56cffe07d 227 SMART SM00986 50 210 1.3E-34 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CXR48_RS17965 5340f1b19b292bddb21dfde56cffe07d 227 Gene3D G3DSA:3.40.470.10 1 225 2.0E-102 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CXR48_RS17965 5340f1b19b292bddb21dfde56cffe07d 227 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 41.256 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CXR48_RS13405 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 Gene3D G3DSA:3.60.90.10 1 124 3.1E-42 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CXR48_RS13405 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 116 31.684 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CXR48_RS13405 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 SUPERFAMILY SSF56276 2 113 1.47E-40 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CXR48_RS13405 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 112 6.9E-41 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CXR48_RS13405 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 Pfam PF02675 S-adenosylmethionine decarboxylase 7 112 1.3E-36 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CXR48_RS00700 a0aefc902b82715fd0f30fe1805ddfc7 82 Hamap MF_00574 Putative ribosomal protein L7Ae-like. 2 82 22.681 T 29-03-2018 IPR023460 Ribosomal protein L7Ae, putative CXR48_RS00700 a0aefc902b82715fd0f30fe1805ddfc7 82 Gene3D G3DSA:3.30.1330.30 2 82 4.8E-15 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CXR48_RS00700 a0aefc902b82715fd0f30fe1805ddfc7 82 SUPERFAMILY SSF55315 4 81 1.66E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CXR48_RS00700 a0aefc902b82715fd0f30fe1805ddfc7 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 80 5.0E-14 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CXR48_RS13625 76e7f90c692f25265381409d20d83f81 531 Gene3D G3DSA:3.20.20.140 180 467 1.5E-47 T 29-03-2018 CXR48_RS13625 76e7f90c692f25265381409d20d83f81 531 SUPERFAMILY SSF51556 60 121 1.53E-28 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS13625 76e7f90c692f25265381409d20d83f81 531 SUPERFAMILY SSF51556 196 484 1.53E-28 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS13625 76e7f90c692f25265381409d20d83f81 531 SUPERFAMILY SSF51338 3 61 4.78E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS13625 76e7f90c692f25265381409d20d83f81 531 SUPERFAMILY SSF51338 484 526 4.78E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS13625 76e7f90c692f25265381409d20d83f81 531 Gene3D G3DSA:2.30.40.10 468 531 4.8E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS13625 76e7f90c692f25265381409d20d83f81 531 Gene3D G3DSA:2.30.40.10 2 112 8.0E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS13625 76e7f90c692f25265381409d20d83f81 531 Pfam PF07969 Amidohydrolase family 49 525 8.6E-126 T 29-03-2018 IPR013108 Amidohydrolase 3 CXR48_RS01765 5e8502c80baa1b72ebeebec2945ab5f6 145 Pfam PF14040 Deoxyribonuclease NucA/NucB 49 131 5.3E-11 T 29-03-2018 IPR029476 Deoxyribonuclease NucA/NucB CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 SUPERFAMILY SSF51569 5 286 3.77E-101 T 29-03-2018 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 64.005 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 288 8.0E-123 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 6.6E-37 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 6.6E-37 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 6.6E-37 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 6.6E-37 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 SMART SM01130 2 289 2.4E-135 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PIRSF PIRSF001365 1 289 2.4E-96 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 Gene3D G3DSA:3.20.20.70 2 289 6.1E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS08365 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 7.0E-122 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CXR48_RS03405 04be5ec09c08add8f5baa7b409c3a97d 282 Gene3D G3DSA:1.10.10.60 40 229 1.9E-11 T 29-03-2018 CXR48_RS03405 04be5ec09c08add8f5baa7b409c3a97d 282 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CXR48_RS03405 04be5ec09c08add8f5baa7b409c3a97d 282 SUPERFAMILY SSF46689 3 68 1.6E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS03405 04be5ec09c08add8f5baa7b409c3a97d 282 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 4.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS03405 04be5ec09c08add8f5baa7b409c3a97d 282 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 4.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS03405 04be5ec09c08add8f5baa7b409c3a97d 282 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 6.3E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS03405 04be5ec09c08add8f5baa7b409c3a97d 282 Gene3D G3DSA:1.10.10.60 2 39 1.3E-16 T 29-03-2018 CXR48_RS05315 e95881e85319a4ba08c113aa2b851667 205 Gene3D G3DSA:3.90.20.10 2 196 1.7E-8 T 29-03-2018 CXR48_RS05315 e95881e85319a4ba08c113aa2b851667 205 Pfam PF10737 Spore germination protein GerPC 24 196 4.3E-63 T 29-03-2018 IPR019673 Spore germination protein GerPC CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 245 1.2E-64 T 29-03-2018 CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 SUPERFAMILY SSF51735 3 248 3.77E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS04185 a90f03ea961bab6abf8dee11b96b0476 250 Gene3D G3DSA:3.40.50.720 1 250 2.8E-65 T 29-03-2018 CXR48_RS16640 891e245496171b77b199febb3947f41c 133 Gene3D G3DSA:1.20.120.340 1 122 2.7E-39 T 29-03-2018 CXR48_RS16640 891e245496171b77b199febb3947f41c 133 SUPERFAMILY SSF101116 4 123 1.14E-38 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CXR48_RS16640 891e245496171b77b199febb3947f41c 133 Pfam PF02561 Flagellar protein FliS 8 119 1.1E-37 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CXR48_RS16640 891e245496171b77b199febb3947f41c 133 PIRSF PIRSF039090 1 129 1.8E-36 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CXR48_RS16640 891e245496171b77b199febb3947f41c 133 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 122 2.0E-42 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CXR48_RS11285 d19ef937e33f6fa1c4a2f374cfdf60fd 129 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 109 8.6E-11 T 29-03-2018 CXR48_RS11285 d19ef937e33f6fa1c4a2f374cfdf60fd 129 Gene3D G3DSA:3.10.180.10 1 129 1.4E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS11285 d19ef937e33f6fa1c4a2f374cfdf60fd 129 SUPERFAMILY SSF54593 1 127 6.6E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS07650 d80bd7d3d039c04fa275ae4c5663a7fa 263 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 20 258 3.1E-70 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CXR48_RS07650 d80bd7d3d039c04fa275ae4c5663a7fa 263 Gene3D G3DSA:3.60.140.10 4 263 1.2E-77 T 29-03-2018 CXR48_RS07650 d80bd7d3d039c04fa275ae4c5663a7fa 263 SUPERFAMILY SSF64438 12 261 3.11E-80 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CXR48_RS07650 d80bd7d3d039c04fa275ae4c5663a7fa 263 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 25 261 1.5E-66 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CXR48_RS02220 b0f4b233a97b787460968bb490a997bb 606 Pfam PF13520 Amino acid permease 27 435 3.7E-35 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS10650 ef848561b39dc067b723d3dc3de4ae9d 137 SMART SM00851 14 107 5.8E-24 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS10650 ef848561b39dc067b723d3dc3de4ae9d 137 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 29-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CXR48_RS10650 ef848561b39dc067b723d3dc3de4ae9d 137 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 1 119 4.8E-63 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CXR48_RS10650 ef848561b39dc067b723d3dc3de4ae9d 137 SUPERFAMILY SSF52335 1 127 1.57E-50 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS10650 ef848561b39dc067b723d3dc3de4ae9d 137 PIRSF PIRSF006614 1 132 8.2E-60 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CXR48_RS10650 ef848561b39dc067b723d3dc3de4ae9d 137 Pfam PF02142 MGS-like domain 14 107 1.8E-18 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS10650 ef848561b39dc067b723d3dc3de4ae9d 137 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 37.074 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CXR48_RS10650 ef848561b39dc067b723d3dc3de4ae9d 137 Gene3D G3DSA:3.40.50.1380 1 123 1.6E-35 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CXR48_RS16670 4d65bcf3e8cbbc007c62d98d34226120 305 Gene3D G3DSA:1.20.1330.10 38 278 4.9E-34 T 29-03-2018 CXR48_RS16670 4d65bcf3e8cbbc007c62d98d34226120 305 SUPERFAMILY SSF64518 1 305 2.88E-67 T 29-03-2018 CXR48_RS16670 4d65bcf3e8cbbc007c62d98d34226120 305 Pfam PF00669 Bacterial flagellin N-terminal helical region 7 139 2.9E-22 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CXR48_RS16670 4d65bcf3e8cbbc007c62d98d34226120 305 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 160 1.3E-53 T 29-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 PIRSF PIRSF036979 1 294 7.1E-40 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 TIGRFAM TIGR01229 rocF_arginase: arginase 6 296 1.3E-121 T 29-03-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 ProSitePatterns PS01053 Arginase family signature. 221 242 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 Pfam PF00491 Arginase family 4 291 9.1E-83 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 218 247 9.2E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 93 108 9.2E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 253 267 9.2E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 116 143 9.2E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 170 188 9.2E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 Gene3D G3DSA:3.40.800.10 1 294 2.8E-94 T 29-03-2018 CXR48_RS18940 5e639fc84490f97e49b7a3bc0558b94d 296 SUPERFAMILY SSF52768 4 294 3.24E-95 T 29-03-2018 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 PRINTS PR00118 Beta-lactamase class A signature 221 236 6.5E-70 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 PRINTS PR00118 Beta-lactamase class A signature 185 210 6.5E-70 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 PRINTS PR00118 Beta-lactamase class A signature 52 76 6.5E-70 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 PRINTS PR00118 Beta-lactamase class A signature 83 100 6.5E-70 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 PRINTS PR00118 Beta-lactamase class A signature 238 253 6.5E-70 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 PRINTS PR00118 Beta-lactamase class A signature 159 183 6.5E-70 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 PRINTS PR00118 Beta-lactamase class A signature 123 148 6.5E-70 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 ProSitePatterns PS00146 Beta-lactamase class-A active site. 85 100 - T 29-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 Gene3D G3DSA:3.40.710.10 50 304 1.0E-30 T 29-03-2018 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 Pfam PF13354 Beta-lactamase enzyme family 73 278 1.1E-34 T 29-03-2018 CXR48_RS05910 64c0783a947e04fc54cb747c34000e2f 306 SUPERFAMILY SSF56601 51 301 1.14E-75 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS17855 88d3a969370ed0cd66a63c0c2b6ee7f9 412 Gene3D G3DSA:1.20.1250.20 212 410 6.1E-29 T 29-03-2018 CXR48_RS17855 88d3a969370ed0cd66a63c0c2b6ee7f9 412 PRINTS PR01035 Tetracycline resistance protein signature 144 166 4.3E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS17855 88d3a969370ed0cd66a63c0c2b6ee7f9 412 PRINTS PR01035 Tetracycline resistance protein signature 86 110 4.3E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS17855 88d3a969370ed0cd66a63c0c2b6ee7f9 412 PRINTS PR01035 Tetracycline resistance protein signature 351 374 4.3E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS17855 88d3a969370ed0cd66a63c0c2b6ee7f9 412 PRINTS PR01035 Tetracycline resistance protein signature 55 74 4.3E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS17855 88d3a969370ed0cd66a63c0c2b6ee7f9 412 SUPERFAMILY SSF103473 20 404 3.4E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS17855 88d3a969370ed0cd66a63c0c2b6ee7f9 412 Gene3D G3DSA:1.20.1250.20 6 209 9.7E-36 T 29-03-2018 CXR48_RS17855 88d3a969370ed0cd66a63c0c2b6ee7f9 412 Pfam PF07690 Major Facilitator Superfamily 24 308 7.9E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS05420 9fdc273c6890757a344506b76ccb511e 325 Gene3D G3DSA:3.40.50.2300 31 146 9.1E-38 T 29-03-2018 CXR48_RS05420 9fdc273c6890757a344506b76ccb511e 325 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 37 301 2.2E-64 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CXR48_RS05420 9fdc273c6890757a344506b76ccb511e 325 Gene3D G3DSA:3.40.50.2300 147 323 1.2E-39 T 29-03-2018 CXR48_RS05420 9fdc273c6890757a344506b76ccb511e 325 SUPERFAMILY SSF53822 31 274 2.0E-16 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS11960 931244dbffb236fefb2fa03eb72319d9 184 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 2 179 9.9E-57 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CXR48_RS11960 931244dbffb236fefb2fa03eb72319d9 184 Gene3D G3DSA:3.40.50.10420 1 184 3.3E-58 T 29-03-2018 CXR48_RS11960 931244dbffb236fefb2fa03eb72319d9 184 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 179 5.1E-53 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CXR48_RS11960 931244dbffb236fefb2fa03eb72319d9 184 PIRSF PIRSF006806 1 182 1.0E-54 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CXR48_RS11960 931244dbffb236fefb2fa03eb72319d9 184 SUPERFAMILY SSF100950 2 183 1.53E-51 T 29-03-2018 CXR48_RS11830 d87c3d52624aba6cbafa12153f79f6be 194 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 6 168 9.2E-54 T 29-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CXR48_RS11830 d87c3d52624aba6cbafa12153f79f6be 194 Gene3D G3DSA:2.10.109.10 41 158 7.9E-10 T 29-03-2018 CXR48_RS11830 d87c3d52624aba6cbafa12153f79f6be 194 SUPERFAMILY SSF51306 40 104 1.46E-9 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS11830 d87c3d52624aba6cbafa12153f79f6be 194 Pfam PF00717 Peptidase S24-like 47 97 2.0E-9 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS11830 d87c3d52624aba6cbafa12153f79f6be 194 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 105 116 3.4E-7 T 29-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CXR48_RS11830 d87c3d52624aba6cbafa12153f79f6be 194 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 47 62 3.4E-7 T 29-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CXR48_RS10125 f6d689a7bb18d55a57976780b293418e 42 TIGRFAM TIGR03093 SASP_sspL: small, acid-soluble spore protein L 6 41 6.1E-21 T 29-03-2018 IPR017526 Small acid-soluble spore protein, SspL CXR48_RS02015 08c2e8bf8f3e3fb393fb89a5a36e8cf1 469 Gene3D G3DSA:3.40.640.10 127 367 3.0E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS02015 08c2e8bf8f3e3fb393fb89a5a36e8cf1 469 SMART SM00345 19 78 3.8E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02015 08c2e8bf8f3e3fb393fb89a5a36e8cf1 469 Pfam PF00155 Aminotransferase class I and II 116 407 1.9E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS02015 08c2e8bf8f3e3fb393fb89a5a36e8cf1 469 Gene3D G3DSA:1.10.10.10 1 91 4.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02015 08c2e8bf8f3e3fb393fb89a5a36e8cf1 469 SUPERFAMILY SSF53383 102 465 2.45E-67 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS02015 08c2e8bf8f3e3fb393fb89a5a36e8cf1 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 5.9E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS02015 08c2e8bf8f3e3fb393fb89a5a36e8cf1 469 Gene3D G3DSA:3.90.1150.10 368 467 1.2E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS02015 08c2e8bf8f3e3fb393fb89a5a36e8cf1 469 SUPERFAMILY SSF46785 15 86 6.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16200 b51f32efb1633eaf785f6b57f98aac5e 226 Pfam PF13614 AAA domain 51 206 5.2E-12 T 29-03-2018 IPR025669 AAA domain CXR48_RS16200 b51f32efb1633eaf785f6b57f98aac5e 226 SUPERFAMILY SSF52540 45 219 4.21E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16200 b51f32efb1633eaf785f6b57f98aac5e 226 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 26 225 9.7E-65 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CXR48_RS16200 b51f32efb1633eaf785f6b57f98aac5e 226 Gene3D G3DSA:3.40.50.300 13 225 3.8E-36 T 29-03-2018 CXR48_RS16385 d05e86cacf544e45523bf382b72d67e2 155 Pfam PF00293 NUDIX domain 5 122 7.0E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CXR48_RS16385 d05e86cacf544e45523bf382b72d67e2 155 PRINTS PR00502 NUDIX hydrolase family signature 26 40 9.9E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS16385 d05e86cacf544e45523bf382b72d67e2 155 PRINTS PR00502 NUDIX hydrolase family signature 40 55 9.9E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS16385 d05e86cacf544e45523bf382b72d67e2 155 SUPERFAMILY SSF55811 4 128 1.35E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CXR48_RS16385 d05e86cacf544e45523bf382b72d67e2 155 Gene3D G3DSA:3.90.79.10 1 153 6.4E-27 T 29-03-2018 CXR48_RS04105 81639b3436f035147af795d1dfc9a8b8 299 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 1.2E-15 T 29-03-2018 IPR013549 Domain of unknown function DUF1731 CXR48_RS04105 81639b3436f035147af795d1dfc9a8b8 299 SUPERFAMILY SSF51735 1 294 1.56E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS04105 81639b3436f035147af795d1dfc9a8b8 299 Gene3D G3DSA:3.40.50.720 2 299 5.5E-37 T 29-03-2018 CXR48_RS04105 81639b3436f035147af795d1dfc9a8b8 299 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 1.9E-107 T 29-03-2018 IPR010099 Epimerase family protein SDR39U1 CXR48_RS04105 81639b3436f035147af795d1dfc9a8b8 299 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 4.8E-19 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CXR48_RS06320 aec134385edf56b0831f2a75f8029ee7 141 Gene3D G3DSA:3.10.450.40 12 130 2.7E-14 T 29-03-2018 CXR48_RS06320 aec134385edf56b0831f2a75f8029ee7 141 Pfam PF10934 Protein of unknown function (DUF2634) 25 124 4.4E-26 T 29-03-2018 IPR020288 Protein of unknown function DUF2634 CXR48_RS06320 aec134385edf56b0831f2a75f8029ee7 141 SUPERFAMILY SSF160719 37 125 8.63E-6 T 29-03-2018 CXR48_RS06320 aec134385edf56b0831f2a75f8029ee7 141 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 11 135 1.0E-52 T 29-03-2018 IPR020288 Protein of unknown function DUF2634 CXR48_RS03425 183c91fa2316f89d5c0bcab1ba231388 650 Gene3D G3DSA:3.40.50.300 241 422 1.8E-13 T 29-03-2018 CXR48_RS03425 183c91fa2316f89d5c0bcab1ba231388 650 SUPERFAMILY SSF52540 164 384 5.0E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03425 183c91fa2316f89d5c0bcab1ba231388 650 SMART SM00382 264 410 4.9E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03425 183c91fa2316f89d5c0bcab1ba231388 650 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 265 611 1.2E-100 T 29-03-2018 IPR018647 Domain of unknown function DUF2075 CXR48_RS15410 4cf609adc7c9ecbd8594fdd432916239 274 Pfam PF00005 ABC transporter 20 167 5.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15410 4cf609adc7c9ecbd8594fdd432916239 274 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15410 4cf609adc7c9ecbd8594fdd432916239 274 SMART SM00382 28 225 3.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15410 4cf609adc7c9ecbd8594fdd432916239 274 Gene3D G3DSA:3.40.50.300 1 246 1.0E-60 T 29-03-2018 CXR48_RS15410 4cf609adc7c9ecbd8594fdd432916239 274 SUPERFAMILY SSF52540 4 229 1.74E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11785 e3a9d08fce04ea1cb1494fd1f1a55a69 126 Gene3D G3DSA:3.40.250.10 22 123 1.1E-29 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS11785 e3a9d08fce04ea1cb1494fd1f1a55a69 126 SUPERFAMILY SSF52821 8 119 3.01E-35 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS11785 e3a9d08fce04ea1cb1494fd1f1a55a69 126 SMART SM00450 29 124 1.1E-32 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS11785 e3a9d08fce04ea1cb1494fd1f1a55a69 126 Pfam PF00581 Rhodanese-like domain 41 119 1.5E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS05065 316f32ee372ea10970ac4433fe65da1b 190 Gene3D G3DSA:1.10.10.60 1 57 5.9E-15 T 29-03-2018 CXR48_RS05065 316f32ee372ea10970ac4433fe65da1b 190 SUPERFAMILY SSF46689 4 77 2.64E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS05065 316f32ee372ea10970ac4433fe65da1b 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS05065 316f32ee372ea10970ac4433fe65da1b 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS05065 316f32ee372ea10970ac4433fe65da1b 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CXR48_RS05065 316f32ee372ea10970ac4433fe65da1b 190 Gene3D G3DSA:1.10.357.10 58 185 1.3E-17 T 29-03-2018 CXR48_RS05065 316f32ee372ea10970ac4433fe65da1b 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 4.4E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS05065 316f32ee372ea10970ac4433fe65da1b 190 SUPERFAMILY SSF48498 81 188 1.5E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS12820 c28f369e2e9533a7b3bd34b1712953f1 367 Gene3D G3DSA:3.40.50.10800 238 341 6.4E-24 T 29-03-2018 CXR48_RS12820 c28f369e2e9533a7b3bd34b1712953f1 367 Hamap MF_00569 Quinolinate synthase A [nadA]. 22 366 55.998 T 29-03-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CXR48_RS12820 c28f369e2e9533a7b3bd34b1712953f1 367 Gene3D G3DSA:3.40.50.10800 112 237 3.5E-25 T 29-03-2018 CXR48_RS12820 c28f369e2e9533a7b3bd34b1712953f1 367 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 21 365 7.0E-124 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CXR48_RS12820 c28f369e2e9533a7b3bd34b1712953f1 367 Gene3D G3DSA:3.40.50.10800 19 107 8.2E-17 T 29-03-2018 CXR48_RS12820 c28f369e2e9533a7b3bd34b1712953f1 367 SUPERFAMILY SSF142754 33 365 1.96E-95 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CXR48_RS12820 c28f369e2e9533a7b3bd34b1712953f1 367 Pfam PF02445 Quinolinate synthetase A protein 29 364 8.5E-106 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CXR48_RS08040 b6db5f03da154c0825f2cfb931b637d2 435 SUPERFAMILY SSF51905 4 367 8.33E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS08040 b6db5f03da154c0825f2cfb931b637d2 435 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 4 435 9.0E-250 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CXR48_RS08040 b6db5f03da154c0825f2cfb931b637d2 435 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CXR48_RS08040 b6db5f03da154c0825f2cfb931b637d2 435 Gene3D G3DSA:3.50.50.60 2 381 4.3E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS08040 b6db5f03da154c0825f2cfb931b637d2 435 Pfam PF01134 Glucose inhibited division protein A 6 367 1.5E-118 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CXR48_RS08040 b6db5f03da154c0825f2cfb931b637d2 435 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 6 434 36.941 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CXR48_RS16485 dc8fbe3855d348e427ff41b871e07911 310 Pfam PF02603 HPr Serine kinase N terminus 4 127 3.9E-39 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CXR48_RS16485 dc8fbe3855d348e427ff41b871e07911 310 Gene3D G3DSA:3.40.1390.20 3 132 6.4E-43 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CXR48_RS16485 dc8fbe3855d348e427ff41b871e07911 310 Gene3D G3DSA:3.40.50.300 133 307 1.7E-47 T 29-03-2018 CXR48_RS16485 dc8fbe3855d348e427ff41b871e07911 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 7 301 3.1E-117 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CXR48_RS16485 dc8fbe3855d348e427ff41b871e07911 310 SUPERFAMILY SSF53795 132 298 8.55E-41 T 29-03-2018 CXR48_RS16485 dc8fbe3855d348e427ff41b871e07911 310 SUPERFAMILY SSF75138 4 131 1.31E-38 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CXR48_RS16485 dc8fbe3855d348e427ff41b871e07911 310 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 8.8E-77 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CXR48_RS16485 dc8fbe3855d348e427ff41b871e07911 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 42.017 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CXR48_RS10620 41e3d16553005e67eb88b35630cfdad6 286 Pfam PF02569 Pantoate-beta-alanine ligase 4 277 7.6E-97 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CXR48_RS10620 41e3d16553005e67eb88b35630cfdad6 286 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 279 3.7E-116 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CXR48_RS10620 41e3d16553005e67eb88b35630cfdad6 286 Gene3D G3DSA:3.30.1300.10 175 286 4.5E-30 T 29-03-2018 CXR48_RS10620 41e3d16553005e67eb88b35630cfdad6 286 Gene3D G3DSA:3.40.50.620 1 174 7.6E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS10620 41e3d16553005e67eb88b35630cfdad6 286 Hamap MF_00158 Pantothenate synthetase [panC]. 2 278 37.394 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CXR48_RS10620 41e3d16553005e67eb88b35630cfdad6 286 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 74 2.3E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CXR48_RS10620 41e3d16553005e67eb88b35630cfdad6 286 SUPERFAMILY SSF52374 1 280 5.23E-100 T 29-03-2018 CXR48_RS05215 bfaf9a1db67d28b545c60e0b10211533 489 Pfam PF00474 Sodium:solute symporter family 35 428 1.4E-21 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS02120 9ed1bf72116c4cdbe0508dd518718070 213 Gene3D G3DSA:3.40.50.1110 4 203 9.8E-24 T 29-03-2018 CXR48_RS02120 9ed1bf72116c4cdbe0508dd518718070 213 SUPERFAMILY SSF52266 6 202 4.89E-23 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS02120 9ed1bf72116c4cdbe0508dd518718070 213 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 197 9.8E-21 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 11 309 1.4E-133 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 29-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 Gene3D G3DSA:3.90.110.10 148 313 2.0E-54 T 29-03-2018 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 Gene3D G3DSA:3.40.50.720 8 147 1.6E-37 T 29-03-2018 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 SUPERFAMILY SSF56327 147 311 2.16E-60 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 SUPERFAMILY SSF51735 3 146 5.24E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 PIRSF PIRSF000102 3 314 7.4E-116 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 6 315 47.755 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 8 146 5.7E-49 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 316 4.8E-43 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 2.6E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 2.6E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 8 32 2.6E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 2.6E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS01620 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 2.6E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CXR48_RS06165 ab2bafe89f896e9df0da65c412929b7f 378 Pfam PF13424 Tetratricopeptide repeat 221 293 3.1E-8 T 29-03-2018 CXR48_RS06165 ab2bafe89f896e9df0da65c412929b7f 378 SUPERFAMILY SSF48452 105 307 7.05E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS06165 ab2bafe89f896e9df0da65c412929b7f 378 SMART SM00028 336 369 280.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS06165 ab2bafe89f896e9df0da65c412929b7f 378 SMART SM00028 222 255 2.9E-6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS06165 ab2bafe89f896e9df0da65c412929b7f 378 SMART SM00028 261 294 130.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS06165 ab2bafe89f896e9df0da65c412929b7f 378 Gene3D G3DSA:1.25.40.10 154 375 2.7E-30 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS06165 ab2bafe89f896e9df0da65c412929b7f 378 Gene3D G3DSA:1.25.40.10 3 153 5.7E-30 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS01140 dfe697c4d6cd0222bb6e6df43210f7c4 143 Pfam PF01047 MarR family 35 91 8.7E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS01140 dfe697c4d6cd0222bb6e6df43210f7c4 143 Gene3D G3DSA:1.10.10.10 7 141 8.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01140 dfe697c4d6cd0222bb6e6df43210f7c4 143 SMART SM00347 27 127 3.8E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS01140 dfe697c4d6cd0222bb6e6df43210f7c4 143 SUPERFAMILY SSF46785 25 141 2.39E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01140 dfe697c4d6cd0222bb6e6df43210f7c4 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CXR48_RS01140 dfe697c4d6cd0222bb6e6df43210f7c4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 3.9E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS01140 dfe697c4d6cd0222bb6e6df43210f7c4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 3.9E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS01140 dfe697c4d6cd0222bb6e6df43210f7c4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 3.9E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS01140 dfe697c4d6cd0222bb6e6df43210f7c4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 3.9E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS01475 9185c41c725c78507afbe3db39d2fccb 214 SUPERFAMILY SSF53474 35 143 1.02E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS01475 9185c41c725c78507afbe3db39d2fccb 214 Gene3D G3DSA:3.40.50.1820 35 214 1.1E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS01475 9185c41c725c78507afbe3db39d2fccb 214 Pfam PF01674 Lipase (class 2) 37 131 6.5E-13 T 29-03-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CXR48_RS13265 0baea27ba4eb6bad5baea694a0dc585f 499 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 291 490 1.7E-39 T 29-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CXR48_RS13265 0baea27ba4eb6bad5baea694a0dc585f 499 SUPERFAMILY SSF51011 369 497 1.51E-41 T 29-03-2018 CXR48_RS13265 0baea27ba4eb6bad5baea694a0dc585f 499 Gene3D G3DSA:3.20.20.80 18 372 4.0E-114 T 29-03-2018 CXR48_RS13265 0baea27ba4eb6bad5baea694a0dc585f 499 SMART SM00813 291 490 5.9E-87 T 29-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CXR48_RS13265 0baea27ba4eb6bad5baea694a0dc585f 499 Gene3D G3DSA:2.60.40.1180 373 499 4.8E-32 T 29-03-2018 CXR48_RS13265 0baea27ba4eb6bad5baea694a0dc585f 499 SUPERFAMILY SSF51445 17 381 5.69E-115 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS15470 63a4478212b03d0b0ab2fb50cb10faa2 480 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 21 467 1.1E-164 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS15470 63a4478212b03d0b0ab2fb50cb10faa2 480 PIRSF PIRSF005690 1 480 1.4E-174 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS03455 357576dfdf8ec54878e0bedc168347de 153 Pfam PF04634 Protein of unknown function, DUF600 2 147 2.9E-48 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03455 357576dfdf8ec54878e0bedc168347de 153 TIGRFAM TIGR01741 staph_tand_hypo: conserved hypothetical protein 2 151 2.0E-46 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03455 357576dfdf8ec54878e0bedc168347de 153 SUPERFAMILY SSF160424 2 151 5.89E-47 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CXR48_RS03455 357576dfdf8ec54878e0bedc168347de 153 Gene3D G3DSA:3.30.500.20 1 112 6.3E-32 T 29-03-2018 CXR48_RS08070 5553831056080a8e6e43a93741dc3fa5 150 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 100 146 2.8E-10 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CXR48_RS08070 5553831056080a8e6e43a93741dc3fa5 150 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CXR48_RS08070 5553831056080a8e6e43a93741dc3fa5 150 Pfam PF00460 Flagella basal body rod protein 7 37 5.3E-12 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CXR48_RS08070 5553831056080a8e6e43a93741dc3fa5 150 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 150 1.2E-51 T 29-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CXR48_RS17265 9184ca14d539a8799055f913a17d92f2 191 Gene3D G3DSA:1.20.144.10 13 171 2.3E-23 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CXR48_RS17265 9184ca14d539a8799055f913a17d92f2 191 SMART SM00014 53 160 2.9E-26 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CXR48_RS17265 9184ca14d539a8799055f913a17d92f2 191 Pfam PF01569 PAP2 superfamily 54 163 7.2E-18 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CXR48_RS17265 9184ca14d539a8799055f913a17d92f2 191 SUPERFAMILY SSF48317 2 168 3.79E-36 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CXR48_RS03355 378d311b50c0b48d62d335af96a2b784 229 Gene3D G3DSA:3.20.20.390 2 224 2.4E-27 T 29-03-2018 CXR48_RS03355 378d311b50c0b48d62d335af96a2b784 229 Pfam PF01884 PcrB family 2 226 2.1E-96 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CXR48_RS03355 378d311b50c0b48d62d335af96a2b784 229 SUPERFAMILY SSF51395 4 222 5.86E-51 T 29-03-2018 CXR48_RS03355 378d311b50c0b48d62d335af96a2b784 229 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 28.881 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CXR48_RS03355 378d311b50c0b48d62d335af96a2b784 229 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 9 223 1.1E-70 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CXR48_RS05245 472caa7ade5ed2a5a0505b2d24480f07 173 SUPERFAMILY SSF46785 39 163 1.45E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05245 472caa7ade5ed2a5a0505b2d24480f07 173 Pfam PF01047 MarR family 52 110 5.3E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS05245 472caa7ade5ed2a5a0505b2d24480f07 173 Gene3D G3DSA:1.10.10.10 13 166 4.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05245 472caa7ade5ed2a5a0505b2d24480f07 173 SMART SM00347 45 148 1.7E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS11730 af9aaf8051ec01d712a0a9468b0b4d9d 171 PIRSF PIRSF021435 1 171 2.8E-67 T 29-03-2018 IPR014198 Stage III sporulation protein AB CXR48_RS11730 af9aaf8051ec01d712a0a9468b0b4d9d 171 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 171 4.8E-65 T 29-03-2018 IPR014198 Stage III sporulation protein AB CXR48_RS11730 af9aaf8051ec01d712a0a9468b0b4d9d 171 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 171 4.7E-51 T 29-03-2018 IPR014198 Stage III sporulation protein AB CXR48_RS09065 1d50b6e5ab3b24d37e82134dc3a4598a 499 Pfam PF00942 Cellulose binding domain 356 436 1.6E-22 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 CXR48_RS09065 1d50b6e5ab3b24d37e82134dc3a4598a 499 SUPERFAMILY SSF49384 350 498 1.26E-50 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CXR48_RS09065 1d50b6e5ab3b24d37e82134dc3a4598a 499 Gene3D G3DSA:2.60.40.710 342 499 1.6E-50 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 CXR48_RS09065 1d50b6e5ab3b24d37e82134dc3a4598a 499 Gene3D G3DSA:3.20.20.80 31 331 1.2E-57 T 29-03-2018 CXR48_RS09065 1d50b6e5ab3b24d37e82134dc3a4598a 499 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 50 296 2.0E-60 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CXR48_RS09065 1d50b6e5ab3b24d37e82134dc3a4598a 499 SMART SM01067 356 437 3.2E-33 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 CXR48_RS09065 1d50b6e5ab3b24d37e82134dc3a4598a 499 SUPERFAMILY SSF51445 40 334 6.82E-95 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS09065 1d50b6e5ab3b24d37e82134dc3a4598a 499 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 162 171 - T 29-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 Pfam PF01019 Gamma-glutamyltranspeptidase 26 520 1.4E-159 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 10 517 2.1E-186 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 SUPERFAMILY SSF56235 5 524 2.12E-167 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 394 409 1.6E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 102 120 1.6E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 32 57 1.6E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 363 381 1.6E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 421 438 1.6E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 218 234 1.6E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 247 266 1.6E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 339 357 1.6E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS17030 3698c508dfcf93071a4ede4d06b81759 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 120 139 1.6E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS13645 a3266c511c88da3b3f4b6181a9cb4f11 381 Gene3D G3DSA:3.40.640.10 13 250 3.4E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS13645 a3266c511c88da3b3f4b6181a9cb4f11 381 Gene3D G3DSA:3.90.1150.10 251 365 2.4E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS13645 a3266c511c88da3b3f4b6181a9cb4f11 381 PIRSF PIRSF005572 1 380 2.7E-106 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CXR48_RS13645 a3266c511c88da3b3f4b6181a9cb4f11 381 SUPERFAMILY SSF53383 1 375 1.73E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS13645 a3266c511c88da3b3f4b6181a9cb4f11 381 Pfam PF00266 Aminotransferase class-V 2 360 1.7E-76 T 29-03-2018 IPR000192 Aminotransferase class V domain CXR48_RS01810 1a90cd02cbb1dc030cdde7a0f8f3db66 224 Gene3D G3DSA:3.90.470.20 1 111 7.9E-28 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CXR48_RS01810 1a90cd02cbb1dc030cdde7a0f8f3db66 224 Gene3D G3DSA:3.90.470.20 112 206 1.8E-19 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CXR48_RS01810 1a90cd02cbb1dc030cdde7a0f8f3db66 224 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 103 205 4.8E-19 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CXR48_RS01810 1a90cd02cbb1dc030cdde7a0f8f3db66 224 SUPERFAMILY SSF56214 1 96 3.01E-28 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CXR48_RS01810 1a90cd02cbb1dc030cdde7a0f8f3db66 224 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 101 224 3.5E-36 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CXR48_RS01810 1a90cd02cbb1dc030cdde7a0f8f3db66 224 SUPERFAMILY SSF56214 103 222 2.88E-31 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CXR48_RS08910 27e373234cc8f826c0d3dde9ab94a55f 120 SMART SM00448 2 114 1.9E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS08910 27e373234cc8f826c0d3dde9ab94a55f 120 SUPERFAMILY SSF52172 1 118 7.54E-36 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS08910 27e373234cc8f826c0d3dde9ab94a55f 120 Gene3D G3DSA:3.40.50.2300 1 119 7.1E-36 T 29-03-2018 CXR48_RS08910 27e373234cc8f826c0d3dde9ab94a55f 120 Pfam PF00072 Response regulator receiver domain 4 114 1.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS11100 7f4537be5ffbbeab3f237fb099fcd215 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 332 1.9E-152 T 29-03-2018 IPR010894 Stage V sporulation AD CXR48_RS11100 7f4537be5ffbbeab3f237fb099fcd215 338 SUPERFAMILY SSF53901 57 312 5.21E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11100 7f4537be5ffbbeab3f237fb099fcd215 338 Gene3D G3DSA:3.40.47.10 216 337 0.1 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11100 7f4537be5ffbbeab3f237fb099fcd215 338 Gene3D G3DSA:3.40.47.10 47 215 6.8E-12 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS11100 7f4537be5ffbbeab3f237fb099fcd215 338 PIRSF PIRSF011570 1 335 1.3E-166 T 29-03-2018 IPR010894 Stage V sporulation AD CXR48_RS11100 7f4537be5ffbbeab3f237fb099fcd215 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 6 332 5.9E-167 T 29-03-2018 IPR010894 Stage V sporulation AD CXR48_RS16730 fd9af6381f3377e3549349fa3baabd1d 404 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 94 247 2.3E-60 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CXR48_RS16730 fd9af6381f3377e3549349fa3baabd1d 404 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 95 247 5.5E-53 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CXR48_RS13035 fd2ccc75f81854f7f1e9d69ebf6450f4 365 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CXR48_RS13035 fd2ccc75f81854f7f1e9d69ebf6450f4 365 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 351 2.0E-169 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CXR48_RS13035 fd2ccc75f81854f7f1e9d69ebf6450f4 365 Gene3D G3DSA:3.40.718.10 1 360 4.3E-128 T 29-03-2018 CXR48_RS13035 fd2ccc75f81854f7f1e9d69ebf6450f4 365 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 352 2.6E-142 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CXR48_RS13035 fd2ccc75f81854f7f1e9d69ebf6450f4 365 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 356 50.33 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CXR48_RS13035 fd2ccc75f81854f7f1e9d69ebf6450f4 365 SMART SM01329 4 352 5.3E-198 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CXR48_RS13035 fd2ccc75f81854f7f1e9d69ebf6450f4 365 SUPERFAMILY SSF53659 4 356 7.1E-123 T 29-03-2018 CXR48_RS03025 aedd6760180197c87a65aeb08f4fbf94 158 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 138 5.2E-49 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CXR48_RS03025 aedd6760180197c87a65aeb08f4fbf94 158 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 128 3.3E-38 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CXR48_RS03025 aedd6760180197c87a65aeb08f4fbf94 158 Gene3D G3DSA:3.40.50.300 1 152 6.9E-51 T 29-03-2018 CXR48_RS03025 aedd6760180197c87a65aeb08f4fbf94 158 SUPERFAMILY SSF52540 26 116 6.32E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 SMART SM00257 27 70 3.8E-15 T 29-03-2018 IPR018392 LysM domain CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 SMART SM00257 87 130 1.5E-18 T 29-03-2018 IPR018392 LysM domain CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 SUPERFAMILY SSF54106 26 70 1.7E-10 T 29-03-2018 IPR018392 LysM domain CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 Pfam PF01476 LysM domain 88 129 1.1E-15 T 29-03-2018 IPR018392 LysM domain CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 Pfam PF01476 LysM domain 29 69 3.4E-13 T 29-03-2018 IPR018392 LysM domain CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 Gene3D G3DSA:3.90.1720.10 153 274 9.5E-32 T 29-03-2018 CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 Gene3D G3DSA:3.10.350.10 83 152 1.1E-17 T 29-03-2018 CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 Gene3D G3DSA:3.10.350.10 20 82 3.0E-14 T 29-03-2018 CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 SUPERFAMILY SSF54106 86 130 3.4E-12 T 29-03-2018 IPR018392 LysM domain CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 SUPERFAMILY SSF54001 155 274 6.87E-34 T 29-03-2018 CXR48_RS04695 7cb13f6114b86f3f5aa12ce58b25a391 274 Pfam PF00877 NlpC/P60 family 172 272 4.5E-28 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CXR48_RS11110 1393d984faedb7e008998ab1a1fd3ec5 141 Pfam PF13782 Stage V sporulation protein AB 27 135 3.7E-32 T 29-03-2018 IPR020144 Stage V sporulation protein AB CXR48_RS11110 1393d984faedb7e008998ab1a1fd3ec5 141 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 27 138 2.0E-49 T 29-03-2018 IPR020144 Stage V sporulation protein AB CXR48_RS18580 989794e579271bd8d4dc938ca69308e3 512 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 500 45.283 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS18580 989794e579271bd8d4dc938ca69308e3 512 Gene3D G3DSA:1.10.275.10 1 195 2.0E-74 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CXR48_RS18580 989794e579271bd8d4dc938ca69308e3 512 SUPERFAMILY SSF48557 1 496 5.42E-193 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CXR48_RS18580 989794e579271bd8d4dc938ca69308e3 512 Pfam PF00221 Aromatic amino acid lyase 9 466 2.2E-194 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CXR48_RS18580 989794e579271bd8d4dc938ca69308e3 512 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 29-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CXR48_RS18580 989794e579271bd8d4dc938ca69308e3 512 Gene3D G3DSA:1.20.200.10 197 508 1.3E-123 T 29-03-2018 CXR48_RS18580 989794e579271bd8d4dc938ca69308e3 512 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 499 6.4E-230 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CXR48_RS05595 a15d463e5a9fdcbad971c5d0568b2120 304 Gene3D G3DSA:1.10.3720.10 27 292 3.4E-44 T 29-03-2018 CXR48_RS05595 a15d463e5a9fdcbad971c5d0568b2120 304 SUPERFAMILY SSF161098 95 287 9.03E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS05595 a15d463e5a9fdcbad971c5d0568b2120 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 301 6.6E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS05595 a15d463e5a9fdcbad971c5d0568b2120 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 77 3.8E-13 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CXR48_RS15235 a3bae31f65eabb34715503054255cbeb 124 PIRSF PIRSF026568 1 124 4.9E-71 T 29-03-2018 IPR014527 Excinuclease GIY-YIG catalytic domain-containing uncharacterised conserved protein CXR48_RS15235 a3bae31f65eabb34715503054255cbeb 124 Pfam PF01541 GIY-YIG catalytic domain 43 117 3.3E-11 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS15235 a3bae31f65eabb34715503054255cbeb 124 SMART SM00465 43 122 1.5E-13 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS15235 a3bae31f65eabb34715503054255cbeb 124 Gene3D G3DSA:3.40.1440.10 34 124 5.4E-16 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS15235 a3bae31f65eabb34715503054255cbeb 124 SUPERFAMILY SSF82771 42 120 1.31E-14 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS00630 7128b1d01a63e7d0c32f58aa12c13773 143 Gene3D G3DSA:1.10.1520.10 2 137 5.6E-21 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CXR48_RS00630 7128b1d01a63e7d0c32f58aa12c13773 143 PIRSF PIRSF005520 1 139 3.0E-54 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family CXR48_RS00630 7128b1d01a63e7d0c32f58aa12c13773 143 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 7 133 30.485 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family CXR48_RS00630 7128b1d01a63e7d0c32f58aa12c13773 143 SMART SM00535 1 134 3.9E-17 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CXR48_RS00630 7128b1d01a63e7d0c32f58aa12c13773 143 SUPERFAMILY SSF69065 9 130 5.06E-42 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CXR48_RS00630 7128b1d01a63e7d0c32f58aa12c13773 143 Pfam PF00636 Ribonuclease III domain 17 116 4.1E-17 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CXR48_RS00935 8080b00b38eea8b08c759af9ce29eb2a 350 ProSitePatterns PS01215 Mrp family signature. 210 226 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 CXR48_RS00935 8080b00b38eea8b08c759af9ce29eb2a 350 Gene3D G3DSA:3.30.300.130 1 93 1.2E-9 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CXR48_RS00935 8080b00b38eea8b08c759af9ce29eb2a 350 Hamap MF_02040 Iron-sulfur cluster carrier protein. 97 345 33.15 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CXR48_RS00935 8080b00b38eea8b08c759af9ce29eb2a 350 SUPERFAMILY SSF52540 99 313 3.02E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00935 8080b00b38eea8b08c759af9ce29eb2a 350 Gene3D G3DSA:3.40.50.300 94 318 5.3E-52 T 29-03-2018 CXR48_RS00935 8080b00b38eea8b08c759af9ce29eb2a 350 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 109 344 1.6E-83 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CXR48_RS17510 afd5184720a85c8888351d89a694433d 187 SUPERFAMILY SSF46955 1 119 9.16E-9 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS17510 afd5184720a85c8888351d89a694433d 187 Gene3D G3DSA:1.10.1660.10 1 172 1.8E-20 T 29-03-2018 CXR48_RS17510 afd5184720a85c8888351d89a694433d 187 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 1 185 28.141 T 29-03-2018 IPR023522 Chromosome-anchoring protein RacA CXR48_RS17510 afd5184720a85c8888351d89a694433d 187 Pfam PF13411 MerR HTH family regulatory protein 2 62 1.2E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 SMART SM00421 146 203 6.2E-30 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 SMART SM00448 2 115 1.6E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 9.7E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 9.7E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 9.7E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 4.3E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 SUPERFAMILY SSF46894 138 209 2.86E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 Gene3D G3DSA:3.40.50.2300 1 126 6.3E-33 T 29-03-2018 CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 Gene3D G3DSA:1.10.10.10 127 210 1.9E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 SUPERFAMILY SSF52172 2 131 2.13E-32 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS15485 fddb44f2b306d39f5b554be1451b24c7 210 Pfam PF00072 Response regulator receiver domain 4 116 2.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS07165 7716e4ebdd1ca4306f8d69aa7bb0bc28 275 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 3 113 8.8E-16 T 29-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CXR48_RS07165 7716e4ebdd1ca4306f8d69aa7bb0bc28 275 Pfam PF13772 AIG2-like family 185 254 3.3E-6 T 29-03-2018 CXR48_RS07165 7716e4ebdd1ca4306f8d69aa7bb0bc28 275 SUPERFAMILY SSF110857 126 252 5.89E-18 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CXR48_RS07165 7716e4ebdd1ca4306f8d69aa7bb0bc28 275 Gene3D G3DSA:3.10.490.10 123 274 2.6E-20 T 29-03-2018 CXR48_RS07165 7716e4ebdd1ca4306f8d69aa7bb0bc28 275 SUPERFAMILY SSF110857 2 119 5.89E-20 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CXR48_RS07165 7716e4ebdd1ca4306f8d69aa7bb0bc28 275 Gene3D G3DSA:3.10.490.10 1 122 8.9E-19 T 29-03-2018 CXR48_RS14430 9ecc7f021476e35865ee25b5505add19 184 SUPERFAMILY SSF46785 9 159 4.15E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14430 9ecc7f021476e35865ee25b5505add19 184 Gene3D G3DSA:1.10.10.10 3 166 1.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14430 9ecc7f021476e35865ee25b5505add19 184 PIRSF PIRSF006707 1 184 1.5E-53 T 29-03-2018 IPR026282 DNA-binding protein, MJ1563 type CXR48_RS09350 da88f908e2cd7a146d08425caa67d426 122 PIRSF PIRSF021424 1 122 2.5E-75 T 29-03-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 CXR48_RS09350 da88f908e2cd7a146d08425caa67d426 122 ProDom PD077583 REPLICATION TRANSCRIPTION DNA-BINDING TERMINATOR REGULATION TERMINATION 3D-STRUCTURE 11 122 9.0E-58 T 29-03-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 CXR48_RS09350 da88f908e2cd7a146d08425caa67d426 122 Gene3D G3DSA:1.10.10.10 1 122 2.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09350 da88f908e2cd7a146d08425caa67d426 122 Pfam PF02334 Replication terminator protein 1 122 2.1E-78 T 29-03-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 CXR48_RS09350 da88f908e2cd7a146d08425caa67d426 122 SUPERFAMILY SSF46785 7 121 2.68E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07695 230c5797f32d91bfb4c9b361195844e3 153 Pfam PF01252 Signal peptidase (SPase) II 6 145 1.8E-37 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CXR48_RS07695 230c5797f32d91bfb4c9b361195844e3 153 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 2.2E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CXR48_RS07695 230c5797f32d91bfb4c9b361195844e3 153 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 2.2E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CXR48_RS07695 230c5797f32d91bfb4c9b361195844e3 153 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 2.2E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CXR48_RS07695 230c5797f32d91bfb4c9b361195844e3 153 TIGRFAM TIGR00077 lspA: signal peptidase II 2 152 1.1E-52 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CXR48_RS07695 230c5797f32d91bfb4c9b361195844e3 153 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 150 16.327 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CXR48_RS17900 0d6764be13e10f913d781d229111fd16 315 SUPERFAMILY SSF51735 1 312 9.13E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS17900 0d6764be13e10f913d781d229111fd16 315 Gene3D G3DSA:3.40.50.720 2 188 3.7E-37 T 29-03-2018 CXR48_RS17900 0d6764be13e10f913d781d229111fd16 315 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 306 1.4E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS17900 0d6764be13e10f913d781d229111fd16 315 Gene3D G3DSA:3.90.25.10 189 315 3.1E-47 T 29-03-2018 CXR48_RS17900 0d6764be13e10f913d781d229111fd16 315 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 5 314 9.6E-144 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CXR48_RS19210 ee9826e7247affc5b497eed028d55cc0 292 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 21 223 1.2E-49 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS19210 ee9826e7247affc5b497eed028d55cc0 292 PIRSF PIRSF006483 1 291 5.0E-75 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS19210 ee9826e7247affc5b497eed028d55cc0 292 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 229 283 2.3E-18 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CXR48_RS14455 3d2cc62cf5daac827047a65974621960 213 Pfam PF00190 Cupin 33 152 3.9E-12 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS14455 3d2cc62cf5daac827047a65974621960 213 SUPERFAMILY SSF51182 30 172 1.99E-29 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS14455 3d2cc62cf5daac827047a65974621960 213 SMART SM00835 21 158 2.9E-17 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS14455 3d2cc62cf5daac827047a65974621960 213 Gene3D G3DSA:2.60.120.10 24 198 1.1E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS13050 6d0ce5ea8c7d5de6dff82a12727510ad 172 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 9.0E-37 T 29-03-2018 CXR48_RS13050 6d0ce5ea8c7d5de6dff82a12727510ad 172 Gene3D G3DSA:3.30.70.260 2 88 3.4E-24 T 29-03-2018 CXR48_RS13050 6d0ce5ea8c7d5de6dff82a12727510ad 172 SUPERFAMILY SSF55021 80 160 1.18E-25 T 29-03-2018 CXR48_RS13050 6d0ce5ea8c7d5de6dff82a12727510ad 172 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 158 7.8E-67 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CXR48_RS13050 6d0ce5ea8c7d5de6dff82a12727510ad 172 Pfam PF10369 Small subunit of acetolactate synthase 85 158 5.2E-29 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CXR48_RS13050 6d0ce5ea8c7d5de6dff82a12727510ad 172 Pfam PF01842 ACT domain 4 68 1.1E-15 T 29-03-2018 IPR002912 ACT domain CXR48_RS13050 6d0ce5ea8c7d5de6dff82a12727510ad 172 SUPERFAMILY SSF55021 2 77 2.12E-19 T 29-03-2018 CXR48_RS13050 6d0ce5ea8c7d5de6dff82a12727510ad 172 Gene3D G3DSA:3.30.70.1150 89 161 6.6E-31 T 29-03-2018 CXR48_RS12350 b98a19ab0d06f6907bcde0cd9d5513bb 46 Gene3D G3DSA:1.10.287.1100 4 36 6.1E-18 T 29-03-2018 IPR015064 Sporulation inhibitor A CXR48_RS12350 b98a19ab0d06f6907bcde0cd9d5513bb 46 Pfam PF08970 Sporulation inhibitor A 1 44 7.2E-22 T 29-03-2018 IPR015064 Sporulation inhibitor A CXR48_RS12350 b98a19ab0d06f6907bcde0cd9d5513bb 46 SUPERFAMILY SSF100985 1 45 1.57E-16 T 29-03-2018 IPR015064 Sporulation inhibitor A CXR48_RS05100 98e6ca0b0db802a9be9036b81f009cd8 244 Gene3D G3DSA:3.60.15.10 1 244 1.8E-49 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS05100 98e6ca0b0db802a9be9036b81f009cd8 244 SMART SM00849 18 211 6.9E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS05100 98e6ca0b0db802a9be9036b81f009cd8 244 SUPERFAMILY SSF56281 1 242 5.5E-53 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS05100 98e6ca0b0db802a9be9036b81f009cd8 244 Pfam PF12706 Beta-lactamase superfamily domain 31 211 3.8E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS04470 ed9ee139918744fce915f595fa8d43df 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 1.7E-92 T 29-03-2018 IPR010650 PrkA C-terminal domain CXR48_RS04470 ed9ee139918744fce915f595fa8d43df 631 SUPERFAMILY SSF52540 68 178 9.52E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04470 ed9ee139918744fce915f595fa8d43df 631 SUPERFAMILY SSF52540 231 456 9.52E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04470 ed9ee139918744fce915f595fa8d43df 631 Pfam PF08298 PrkA AAA domain 22 371 8.7E-158 T 29-03-2018 IPR013153 PrkA AAA domain CXR48_RS04470 ed9ee139918744fce915f595fa8d43df 631 Gene3D G3DSA:3.40.50.300 36 348 5.3E-8 T 29-03-2018 CXR48_RS04470 ed9ee139918744fce915f595fa8d43df 631 SMART SM00763 21 371 7.8E-198 T 29-03-2018 IPR013153 PrkA AAA domain CXR48_RS04470 ed9ee139918744fce915f595fa8d43df 631 PIRSF PIRSF000549 1 631 2.3E-269 T 29-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 Gene3D G3DSA:2.40.50.140 2 48 2.7E-19 T 29-03-2018 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 Pfam PF07499 RuvA, C-terminal domain 155 199 3.2E-12 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 SMART SM00278 105 124 0.7 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 SMART SM00278 70 89 2.3 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 200 1.3E-66 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 SUPERFAMILY SSF46929 154 199 1.16E-8 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 Pfam PF01330 RuvA N terminal domain 2 59 2.7E-18 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 Gene3D G3DSA:1.10.8.10 153 199 1.3E-9 T 29-03-2018 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 200 28.718 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 SUPERFAMILY SSF50249 2 60 3.26E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 Gene3D G3DSA:1.10.340.30 49 77 0.32 T 29-03-2018 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 SUPERFAMILY SSF47781 62 134 1.11E-20 T 29-03-2018 IPR010994 RuvA domain 2-like CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 Pfam PF14520 Helix-hairpin-helix domain 69 126 4.4E-14 T 29-03-2018 CXR48_RS12795 3d5e49c9322f31022e0160f7ea10d193 201 Gene3D G3DSA:1.10.150.20 78 138 3.2E-14 T 29-03-2018 CXR48_RS12495 5bbbec965e60c7b872d7c2354776dcc6 179 Gene3D G3DSA:3.40.50.150 21 179 4.4E-15 T 29-03-2018 CXR48_RS12495 5bbbec965e60c7b872d7c2354776dcc6 179 Pfam PF08241 Methyltransferase domain 41 139 4.9E-12 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CXR48_RS12495 5bbbec965e60c7b872d7c2354776dcc6 179 SUPERFAMILY SSF53335 32 171 8.2E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS04360 e4300e6b620593aaf10b495bce6f8cf2 573 PIRSF PIRSF002741 17 572 2.2E-112 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CXR48_RS04360 e4300e6b620593aaf10b495bce6f8cf2 573 Gene3D G3DSA:3.40.190.10 206 341 1.6E-27 T 29-03-2018 CXR48_RS04360 e4300e6b620593aaf10b495bce6f8cf2 573 SUPERFAMILY SSF53850 68 562 1.14E-118 T 29-03-2018 CXR48_RS04360 e4300e6b620593aaf10b495bce6f8cf2 573 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 112 482 1.2E-80 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CXR48_RS04360 e4300e6b620593aaf10b495bce6f8cf2 573 Gene3D G3DSA:3.90.76.10 102 205 3.1E-30 T 29-03-2018 CXR48_RS04360 e4300e6b620593aaf10b495bce6f8cf2 573 Gene3D G3DSA:3.10.105.10 342 541 1.5E-48 T 29-03-2018 CXR48_RS17350 91106c37615dfd416ee2e867ad57eb27 341 Gene3D G3DSA:3.20.20.70 4 341 7.3E-88 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS17350 91106c37615dfd416ee2e867ad57eb27 341 Pfam PF13353 4Fe-4S single cluster domain 25 132 3.9E-7 T 29-03-2018 CXR48_RS17350 91106c37615dfd416ee2e867ad57eb27 341 SMART SM00729 17 226 3.4E-23 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CXR48_RS17350 91106c37615dfd416ee2e867ad57eb27 341 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 23 34 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CXR48_RS17350 91106c37615dfd416ee2e867ad57eb27 341 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 8 341 42.392 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CXR48_RS17350 91106c37615dfd416ee2e867ad57eb27 341 SUPERFAMILY SSF102114 9 315 3.66E-82 T 29-03-2018 CXR48_RS17350 91106c37615dfd416ee2e867ad57eb27 341 Pfam PF04055 Radical SAM superfamily 21 186 1.0E-32 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS17350 91106c37615dfd416ee2e867ad57eb27 341 Pfam PF06463 Molybdenum Cofactor Synthesis C 195 320 1.7E-38 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CXR48_RS17350 91106c37615dfd416ee2e867ad57eb27 341 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 9 341 2.7E-120 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CXR48_RS08005 81b320bc1bc5cd4681b66f94431bb0a8 255 Gene3D G3DSA:3.30.420.10 48 255 1.8E-67 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS08005 81b320bc1bc5cd4681b66f94431bb0a8 255 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 251 37.17 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 CXR48_RS08005 81b320bc1bc5cd4681b66f94431bb0a8 255 Pfam PF01351 Ribonuclease HII 75 250 6.7E-32 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain CXR48_RS08005 81b320bc1bc5cd4681b66f94431bb0a8 255 SUPERFAMILY SSF53098 63 254 9.56E-67 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS06820 45e63febbea2d717d0ae6e0bfa877da8 91 Pfam PF11514 Protein of unknown function (DUF3219) 4 91 5.8E-34 T 29-03-2018 IPR021596 Protein of unknown function DUF3219 CXR48_RS06820 45e63febbea2d717d0ae6e0bfa877da8 91 SUPERFAMILY SSF159173 1 91 1.83E-41 T 29-03-2018 IPR023105 YkvR-like domain CXR48_RS06820 45e63febbea2d717d0ae6e0bfa877da8 91 Gene3D G3DSA:2.40.30.80 1 90 2.5E-30 T 29-03-2018 IPR023105 YkvR-like domain CXR48_RS13190 a6574d3120d625d280933b193c38e2ec 224 Pfam PF10924 Protein of unknown function (DUF2711) 11 222 1.6E-75 T 29-03-2018 IPR024250 Protein of unknown function DUF2711 CXR48_RS13190 a6574d3120d625d280933b193c38e2ec 224 ProDom PD114754 YWBB 1 222 6.0E-46 T 29-03-2018 IPR024250 Protein of unknown function DUF2711 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 Gene3D G3DSA:1.25.40.10 1 153 1.7E-29 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 Gene3D G3DSA:1.10.150.200 159 232 2.0E-8 T 29-03-2018 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 Pfam PF13424 Tetratricopeptide repeat 223 287 3.6E-10 T 29-03-2018 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 SMART SM00028 182 215 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 SMART SM00028 222 255 0.0061 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 SMART SM00028 101 134 420.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 SMART SM00028 337 370 150.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 SMART SM00028 262 295 0.037 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 Gene3D G3DSA:1.25.40.10 274 372 2.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 SUPERFAMILY SSF48452 334 367 8.41E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 SUPERFAMILY SSF48452 120 299 8.41E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS17665 6d533ef160d29a07763f29a3b9251179 381 Gene3D G3DSA:1.25.40.10 233 273 1.6E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03935 042069949f93f2af0ae664a2741b77fa 319 SUPERFAMILY SSF143865 24 249 2.62E-62 T 29-03-2018 CXR48_RS03935 042069949f93f2af0ae664a2741b77fa 319 SUPERFAMILY SSF144083 250 312 3.14E-23 T 29-03-2018 CXR48_RS03935 042069949f93f2af0ae664a2741b77fa 319 Gene3D G3DSA:1.20.58.340 247 315 2.0E-25 T 29-03-2018 CXR48_RS03935 042069949f93f2af0ae664a2741b77fa 319 Gene3D G3DSA:1.20.58.340 125 246 1.6E-26 T 29-03-2018 CXR48_RS03935 042069949f93f2af0ae664a2741b77fa 319 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 4 315 1.3E-115 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CXR48_RS03935 042069949f93f2af0ae664a2741b77fa 319 Gene3D G3DSA:3.30.460.20 3 124 5.3E-25 T 29-03-2018 CXR48_RS03935 042069949f93f2af0ae664a2741b77fa 319 Pfam PF01544 CorA-like Mg2+ transporter protein 28 311 1.0E-78 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CXR48_RS16415 326a941223ce930f763d469592dd0545 205 Gene3D G3DSA:3.40.190.10 1 200 3.0E-4 T 29-03-2018 CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 SUPERFAMILY SSF51430 12 267 5.11E-82 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 Pfam PF00248 Aldo/keto reductase family 20 263 4.8E-42 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 Gene3D G3DSA:3.20.20.100 5 279 1.4E-82 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 PRINTS PR00069 Aldo-keto reductase signature 127 144 3.8E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 PRINTS PR00069 Aldo-keto reductase signature 199 223 3.8E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 PRINTS PR00069 Aldo-keto reductase signature 39 63 3.8E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 PRINTS PR00069 Aldo-keto reductase signature 95 113 3.8E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 PRINTS PR00069 Aldo-keto reductase signature 161 190 3.8E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 PIRSF PIRSF000097 5 281 6.7E-74 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS01125 2d3b2a2551d0d952f045e766f487facf 281 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 232 247 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 ProSitePatterns PS00221 MIP family signature. 62 70 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 Pfam PF00230 Major intrinsic protein 3 230 1.1E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 SUPERFAMILY SSF81338 2 234 8.63E-72 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 Gene3D G3DSA:1.20.1080.10 1 241 6.5E-85 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 230 6.7E-67 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 PRINTS PR00783 Major intrinsic protein family signature 81 100 5.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 PRINTS PR00783 Major intrinsic protein family signature 44 68 5.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 PRINTS PR00783 Major intrinsic protein family signature 166 188 5.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 PRINTS PR00783 Major intrinsic protein family signature 2 21 5.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 PRINTS PR00783 Major intrinsic protein family signature 213 233 5.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CXR48_RS04625 2a42373d186abf02e326216c57b2f3f0 275 PRINTS PR00783 Major intrinsic protein family signature 136 154 5.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CXR48_RS07690 f024446de3f6e4f92e80ae02e184053b 123 PIRSF PIRSF026544 1 123 4.2E-58 T 29-03-2018 IPR016841 Transcription regulator DksA-related, predicted CXR48_RS07690 f024446de3f6e4f92e80ae02e184053b 123 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 72 96 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site CXR48_RS18570 506abbaf9f49fe7e2ca6fc57a7fa1fc8 468 Gene3D G3DSA:2.115.10.20 20 365 1.0E-71 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS18570 506abbaf9f49fe7e2ca6fc57a7fa1fc8 468 Gene3D G3DSA:2.40.128.10 375 468 7.4E-29 T 29-03-2018 CXR48_RS18570 506abbaf9f49fe7e2ca6fc57a7fa1fc8 468 Pfam PF04616 Glycosyl hydrolases family 43 31 282 8.5E-32 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CXR48_RS18570 506abbaf9f49fe7e2ca6fc57a7fa1fc8 468 Pfam PF16369 C-terminal of Glycosyl hydrolases family 43 363 466 1.3E-33 T 29-03-2018 IPR032291 Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal CXR48_RS18570 506abbaf9f49fe7e2ca6fc57a7fa1fc8 468 SUPERFAMILY SSF75005 18 360 2.14E-63 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS09415 88429c4982ec3cfabe8201519d7b4e7b 119 Pfam PF01638 HxlR-like helix-turn-helix 15 104 1.4E-39 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CXR48_RS09415 88429c4982ec3cfabe8201519d7b4e7b 119 Gene3D G3DSA:1.10.10.10 13 111 7.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09415 88429c4982ec3cfabe8201519d7b4e7b 119 SUPERFAMILY SSF46785 4 99 1.05E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01320 c657448dacb4f9bed5705a2e67fdb968 271 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 11 263 36.502 T 29-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CXR48_RS01320 c657448dacb4f9bed5705a2e67fdb968 271 Pfam PF02666 Phosphatidylserine decarboxylase 63 261 1.5E-54 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CXR48_RS01320 c657448dacb4f9bed5705a2e67fdb968 271 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 51 262 2.9E-69 T 29-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CXR48_RS07645 3bdf1cc4d9615ecf1e088bb2bf13108d 83 Gene3D G3DSA:2.30.30.240 1 78 1.2E-16 T 29-03-2018 CXR48_RS07645 3bdf1cc4d9615ecf1e088bb2bf13108d 83 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 4 75 2.3E-26 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH CXR48_RS07645 3bdf1cc4d9615ecf1e088bb2bf13108d 83 SUPERFAMILY SSF50346 1 74 2.35E-14 T 29-03-2018 IPR011033 PRC-barrel-like CXR48_RS07645 3bdf1cc4d9615ecf1e088bb2bf13108d 83 Pfam PF05239 PRC-barrel domain 2 77 4.1E-14 T 29-03-2018 IPR027275 PRC-barrel domain CXR48_RS15080 ecd4059bff5b74f2f4106235066c8357 166 PIRSF PIRSF019587 5 166 2.8E-83 T 29-03-2018 IPR026038 Putative phosphatidylglycerophosphatase CXR48_RS15080 ecd4059bff5b74f2f4106235066c8357 166 SUPERFAMILY SSF101307 13 162 1.7E-54 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CXR48_RS15080 ecd4059bff5b74f2f4106235066c8357 166 Gene3D G3DSA:1.10.3760.10 1 166 4.2E-61 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CXR48_RS15080 ecd4059bff5b74f2f4106235066c8357 166 Pfam PF04608 Phosphatidylglycerophosphatase A 23 159 7.4E-19 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CXR48_RS13985 26a7d373bdcb479734d3712884e21790 183 Pfam PF00583 Acetyltransferase (GNAT) family 65 159 9.2E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS13985 26a7d373bdcb479734d3712884e21790 183 Gene3D G3DSA:3.40.630.30 112 172 1.4E-12 T 29-03-2018 CXR48_RS13985 26a7d373bdcb479734d3712884e21790 183 Gene3D G3DSA:3.40.630.30 19 111 6.6E-17 T 29-03-2018 CXR48_RS13985 26a7d373bdcb479734d3712884e21790 183 SUPERFAMILY SSF55729 26 171 4.42E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS04720 0c4d2ce777017d6f6e458a5b8db57314 451 Pfam PF00209 Sodium:neurotransmitter symporter family 6 125 1.8E-24 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS04720 0c4d2ce777017d6f6e458a5b8db57314 451 Pfam PF00209 Sodium:neurotransmitter symporter family 149 445 2.2E-26 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS04720 0c4d2ce777017d6f6e458a5b8db57314 451 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 30 44 - T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS04720 0c4d2ce777017d6f6e458a5b8db57314 451 SUPERFAMILY SSF161070 6 446 2.09E-127 T 29-03-2018 CXR48_RS04720 0c4d2ce777017d6f6e458a5b8db57314 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 14 35 7.1E-12 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS04720 0c4d2ce777017d6f6e458a5b8db57314 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 89 115 7.1E-12 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS04720 0c4d2ce777017d6f6e458a5b8db57314 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 43 62 7.1E-12 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 Gene3D G3DSA:3.50.50.60 2 163 1.1E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 SUPERFAMILY SSF51905 5 322 1.3E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 3.0E-17 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 128 3.0E-17 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 282 300 3.0E-17 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 3.0E-17 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 8.1E-13 T 29-03-2018 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.1E-13 T 29-03-2018 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 8.1E-13 T 29-03-2018 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 8.1E-13 T 29-03-2018 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 Gene3D G3DSA:3.40.50.720 164 327 1.9E-19 T 29-03-2018 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 291 5.1E-101 T 29-03-2018 CXR48_RS10885 e39001285829665da0d1a1dca4f92e55 327 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 320 5.2E-137 T 29-03-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA CXR48_RS13115 de921894d7299764585f31915b2a8abc 145 Gene3D G3DSA:3.10.129.10 17 143 1.0E-27 T 29-03-2018 CXR48_RS13115 de921894d7299764585f31915b2a8abc 145 SUPERFAMILY SSF54637 14 143 8.87E-32 T 29-03-2018 IPR029069 HotDog domain CXR48_RS13115 de921894d7299764585f31915b2a8abc 145 Pfam PF03061 Thioesterase superfamily 34 114 3.4E-11 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CXR48_RS04930 08a8abde8e94dd9ca38a4c3758bf7240 407 Pfam PF00149 Calcineurin-like phosphoesterase 4 202 1.1E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CXR48_RS04930 08a8abde8e94dd9ca38a4c3758bf7240 407 SUPERFAMILY SSF56300 5 297 1.23E-53 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS04930 08a8abde8e94dd9ca38a4c3758bf7240 407 Gene3D G3DSA:3.60.21.10 2 80 4.7E-13 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS04930 08a8abde8e94dd9ca38a4c3758bf7240 407 Gene3D G3DSA:3.60.21.10 81 252 1.1E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS04930 08a8abde8e94dd9ca38a4c3758bf7240 407 PIRSF PIRSF033091 1 407 2.1E-143 T 29-03-2018 IPR014576 Predicted phosphoesterase, YhaO type CXR48_RS14170 00d12989d0b101c183a819531dfa90db 159 Pfam PF00293 NUDIX domain 28 87 1.7E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CXR48_RS14170 00d12989d0b101c183a819531dfa90db 159 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 156 2.3E-66 T 29-03-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 CXR48_RS14170 00d12989d0b101c183a819531dfa90db 159 SUPERFAMILY SSF55811 28 122 7.85E-20 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CXR48_RS14170 00d12989d0b101c183a819531dfa90db 159 Gene3D G3DSA:3.90.79.10 1 158 1.3E-23 T 29-03-2018 CXR48_RS14170 00d12989d0b101c183a819531dfa90db 159 PRINTS PR00502 NUDIX hydrolase family signature 62 77 2.6E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS14170 00d12989d0b101c183a819531dfa90db 159 PRINTS PR00502 NUDIX hydrolase family signature 48 62 2.6E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS14170 00d12989d0b101c183a819531dfa90db 159 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CXR48_RS01095 fe112478f4b7f083c7d3cb468f1f9e8e 273 PIRSF PIRSF004793 2 268 6.4E-100 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CXR48_RS01095 fe112478f4b7f083c7d3cb468f1f9e8e 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 3 256 7.9E-115 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CXR48_RS01095 fe112478f4b7f083c7d3cb468f1f9e8e 273 SUPERFAMILY SSF143597 40 240 5.89E-73 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CXR48_RS01095 fe112478f4b7f083c7d3cb468f1f9e8e 273 Gene3D G3DSA:3.40.1700.10 111 239 1.7E-38 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CXR48_RS01095 fe112478f4b7f083c7d3cb468f1f9e8e 273 Hamap MF_01499 Diadenylate cyclase [dacA]. 1 254 34.923 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CXR48_RS01095 fe112478f4b7f083c7d3cb468f1f9e8e 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 235 1.2E-44 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CXR48_RS06390 b1664c1eec10bbf8874998e02f02f37f 205 Gene3D G3DSA:1.20.58.220 100 204 6.4E-11 T 29-03-2018 CXR48_RS06390 b1664c1eec10bbf8874998e02f02f37f 205 SUPERFAMILY SSF109755 78 197 4.45E-5 T 29-03-2018 CXR48_RS06390 b1664c1eec10bbf8874998e02f02f37f 205 Pfam PF01865 Protein of unknown function DUF47 9 202 1.4E-22 T 29-03-2018 IPR018445 Putative phosphate transport regulator CXR48_RS14165 8a8940584b373f2463b3c47c1b6be928 270 SUPERFAMILY SSF161098 72 253 8.9E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS14165 8a8940584b373f2463b3c47c1b6be928 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 264 2.9E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS14165 8a8940584b373f2463b3c47c1b6be928 270 Gene3D G3DSA:1.10.3720.10 26 269 1.6E-25 T 29-03-2018 CXR48_RS02285 0ace0724e2f7656d610ee5206cb43ad8 121 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.3E-28 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CXR48_RS02285 0ace0724e2f7656d610ee5206cb43ad8 121 SUPERFAMILY SSF103481 5 103 7.98E-19 T 29-03-2018 CXR48_RS15710 99e76c62f04d67c03afad7f51b83bcf1 202 Pfam PF03458 UPF0126 domain 92 161 6.9E-18 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CXR48_RS15710 99e76c62f04d67c03afad7f51b83bcf1 202 Pfam PF03458 UPF0126 domain 5 78 1.2E-18 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CXR48_RS06670 da9ad5c1370fae101805dc984b8fcdb5 64 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CXR48_RS06670 da9ad5c1370fae101805dc984b8fcdb5 64 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CXR48_RS06670 da9ad5c1370fae101805dc984b8fcdb5 64 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 3.0E-24 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CXR48_RS18180 7c1d430c67896751474b92fc4be516ee 395 SUPERFAMILY SSF53335 78 392 6.99E-67 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS18180 7c1d430c67896751474b92fc4be516ee 395 Gene3D G3DSA:3.40.50.150 180 395 1.6E-27 T 29-03-2018 CXR48_RS18180 7c1d430c67896751474b92fc4be516ee 395 Gene3D G3DSA:3.30.750.80 71 178 2.4E-25 T 29-03-2018 CXR48_RS18180 7c1d430c67896751474b92fc4be516ee 395 SMART SM00359 2 87 5.2E-6 T 29-03-2018 IPR002478 PUA domain GO:0003723 CXR48_RS18180 7c1d430c67896751474b92fc4be516ee 395 SUPERFAMILY SSF88697 1 69 1.99E-17 T 29-03-2018 IPR015947 PUA-like domain CXR48_RS18180 7c1d430c67896751474b92fc4be516ee 395 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 102 375 3.8E-36 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CXR48_RS18180 7c1d430c67896751474b92fc4be516ee 395 Gene3D G3DSA:2.30.130.10 4 66 3.0E-17 T 29-03-2018 IPR002478 PUA domain GO:0003723 CXR48_RS03430 164958eb02d99ec7cc09dbfea43d8848 317 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS03430 164958eb02d99ec7cc09dbfea43d8848 317 Pfam PF00005 ABC transporter 24 168 1.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS03430 164958eb02d99ec7cc09dbfea43d8848 317 Gene3D G3DSA:3.40.50.300 2 246 2.8E-68 T 29-03-2018 CXR48_RS03430 164958eb02d99ec7cc09dbfea43d8848 317 SMART SM00382 32 217 2.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS03430 164958eb02d99ec7cc09dbfea43d8848 317 SUPERFAMILY SSF52540 7 231 5.11E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12760 502768274340e9dc3ed68fb8db228aa7 218 Gene3D G3DSA:3.30.240.20 155 214 9.8E-12 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CXR48_RS12760 502768274340e9dc3ed68fb8db228aa7 218 Gene3D G3DSA:3.30.240.20 82 151 9.0E-25 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CXR48_RS12760 502768274340e9dc3ed68fb8db228aa7 218 Pfam PF04239 Protein of unknown function (DUF421) 89 192 6.7E-37 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CXR48_RS10540 3f5902976c47660c1e0538aab3d70fc7 60 Pfam PF14178 YppF-like protein 1 58 1.9E-26 T 29-03-2018 IPR025553 YppF-like protein CXR48_RS10540 3f5902976c47660c1e0538aab3d70fc7 60 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 60 2.0E-25 T 29-03-2018 CXR48_RS14120 d413ab8b6b78693ca90f8ece5c2e2d28 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 13 44 7.6E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS14120 d413ab8b6b78693ca90f8ece5c2e2d28 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 120 1.5E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CXR48_RS14120 d413ab8b6b78693ca90f8ece5c2e2d28 171 Gene3D G3DSA:2.160.10.10 1 171 1.4E-43 T 29-03-2018 CXR48_RS14120 d413ab8b6b78693ca90f8ece5c2e2d28 171 SUPERFAMILY SSF51161 3 168 1.29E-48 T 29-03-2018 IPR011004 Trimeric LpxA-like CXR48_RS18245 ce4133f10b92f16d4e123a16659227fc 78 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 4 76 1.5E-41 T 29-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CXR48_RS18245 ce4133f10b92f16d4e123a16659227fc 78 SUPERFAMILY SSF47336 2 76 9.95E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS18245 ce4133f10b92f16d4e123a16659227fc 78 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 78 51.062 T 29-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CXR48_RS18245 ce4133f10b92f16d4e123a16659227fc 78 Pfam PF00550 Phosphopantetheine attachment site 5 72 8.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS18245 ce4133f10b92f16d4e123a16659227fc 78 Gene3D G3DSA:1.10.1200.10 1 78 1.3E-14 T 29-03-2018 CXR48_RS08545 8c5e705c9314b53897f9cf1dfb78e59f 420 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 266 414 8.5E-12 T 29-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CXR48_RS08545 8c5e705c9314b53897f9cf1dfb78e59f 420 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 4 180 2.1E-11 T 29-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 CXR48_RS08545 8c5e705c9314b53897f9cf1dfb78e59f 420 SUPERFAMILY SSF53901 4 181 1.11E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08545 8c5e705c9314b53897f9cf1dfb78e59f 420 Gene3D G3DSA:3.40.47.10 191 340 1.2E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08545 8c5e705c9314b53897f9cf1dfb78e59f 420 Gene3D G3DSA:3.40.47.10 14 183 5.0E-10 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS08545 8c5e705c9314b53897f9cf1dfb78e59f 420 SUPERFAMILY SSF53901 186 419 1.67E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS17425 b6963ad52c5360a9a725016ca58df5b7 70 Pfam PF00137 ATP synthase subunit C 4 66 9.4E-15 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CXR48_RS17425 b6963ad52c5360a9a725016ca58df5b7 70 SUPERFAMILY SSF81333 3 69 1.83E-19 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CXR48_RS17425 b6963ad52c5360a9a725016ca58df5b7 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 5.6E-20 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17425 b6963ad52c5360a9a725016ca58df5b7 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 5.6E-20 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17425 b6963ad52c5360a9a725016ca58df5b7 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 5.6E-20 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17425 b6963ad52c5360a9a725016ca58df5b7 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 14 69 1.0E-20 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CXR48_RS17425 b6963ad52c5360a9a725016ca58df5b7 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17425 b6963ad52c5360a9a725016ca58df5b7 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 15.863 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CXR48_RS17425 b6963ad52c5360a9a725016ca58df5b7 70 Gene3D G3DSA:1.20.20.10 1 70 2.0E-19 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CXR48_RS08380 a702560d328600bf5de90a94bf77b5ef 69 Gene3D G3DSA:3.10.350.10 2 69 0.0012 T 29-03-2018 CXR48_RS08380 a702560d328600bf5de90a94bf77b5ef 69 Pfam PF14035 YlzJ-like protein 3 65 1.6E-21 T 29-03-2018 IPR025619 YlzJ-like protein CXR48_RS11985 f41f7738ee1ac44db194df6e22f8ca2e 268 SMART SM00382 46 240 1.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS11985 f41f7738ee1ac44db194df6e22f8ca2e 268 SUPERFAMILY SSF52540 17 255 1.54E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11985 f41f7738ee1ac44db194df6e22f8ca2e 268 Gene3D G3DSA:3.40.50.300 7 266 8.9E-61 T 29-03-2018 CXR48_RS11985 f41f7738ee1ac44db194df6e22f8ca2e 268 Pfam PF00005 ABC transporter 37 192 1.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS11985 f41f7738ee1ac44db194df6e22f8ca2e 268 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS11985 f41f7738ee1ac44db194df6e22f8ca2e 268 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 22 268 2.7E-121 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CXR48_RS06440 7f8a321d6f1641576d8459761703b9d7 342 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS06440 7f8a321d6f1641576d8459761703b9d7 342 Pfam PF00005 ABC transporter 26 184 4.3E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS06440 7f8a321d6f1641576d8459761703b9d7 342 Gene3D G3DSA:3.40.50.300 2 336 3.7E-84 T 29-03-2018 CXR48_RS06440 7f8a321d6f1641576d8459761703b9d7 342 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 300 1.2E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS06440 7f8a321d6f1641576d8459761703b9d7 342 SUPERFAMILY SSF52540 5 255 5.44E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS06440 7f8a321d6f1641576d8459761703b9d7 342 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 3.0E-25 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS06440 7f8a321d6f1641576d8459761703b9d7 342 SMART SM00382 34 234 2.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS01905 1bd0abc97c8572119b33bc8f21b9b56a 224 SUPERFAMILY SSF161098 14 204 9.42E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS01905 1bd0abc97c8572119b33bc8f21b9b56a 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 219 4.3E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS01905 1bd0abc97c8572119b33bc8f21b9b56a 224 Gene3D G3DSA:1.10.3720.10 2 224 8.9E-47 T 29-03-2018 CXR48_RS01905 1bd0abc97c8572119b33bc8f21b9b56a 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 113 1.2E-26 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CXR48_RS05730 8c207f8b28c4c082d5ce203a2aab7e20 205 SUPERFAMILY SSF51391 3 196 3.27E-47 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS05730 8c207f8b28c4c082d5ce203a2aab7e20 205 Pfam PF02581 Thiamine monophosphate synthase 4 179 1.6E-39 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS05730 8c207f8b28c4c082d5ce203a2aab7e20 205 Gene3D G3DSA:3.20.20.70 1 197 3.9E-34 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS06970 5f3d98834b511a4047ed0c4e8d7f17a7 406 SMART SM00052 1 241 1.3E-50 T 29-03-2018 IPR001633 EAL domain CXR48_RS06970 5f3d98834b511a4047ed0c4e8d7f17a7 406 SUPERFAMILY SSF141868 6 237 9.15E-45 T 29-03-2018 IPR001633 EAL domain CXR48_RS06970 5f3d98834b511a4047ed0c4e8d7f17a7 406 SUPERFAMILY SSF103190 263 403 1.8E-46 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CXR48_RS06970 5f3d98834b511a4047ed0c4e8d7f17a7 406 Gene3D G3DSA:3.20.20.450 6 250 5.5E-40 T 29-03-2018 IPR001633 EAL domain CXR48_RS06970 5f3d98834b511a4047ed0c4e8d7f17a7 406 Gene3D G3DSA:3.30.450.20 291 406 1.2E-18 T 29-03-2018 CXR48_RS06970 5f3d98834b511a4047ed0c4e8d7f17a7 406 Pfam PF10388 EAL-domain associated signalling protein domain 240 406 4.4E-78 T 29-03-2018 IPR018842 YkuI, C-terminal CXR48_RS06970 5f3d98834b511a4047ed0c4e8d7f17a7 406 Pfam PF00563 EAL domain 13 236 5.4E-33 T 29-03-2018 IPR001633 EAL domain CXR48_RS06970 5f3d98834b511a4047ed0c4e8d7f17a7 406 Gene3D G3DSA:1.20.5.170 251 288 1.2E-16 T 29-03-2018 CXR48_RS02755 962b666ac8bad00ea2bd15441f24e5ab 396 Pfam PF07690 Major Facilitator Superfamily 24 313 1.4E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS02755 962b666ac8bad00ea2bd15441f24e5ab 396 Gene3D G3DSA:1.20.1250.20 203 394 1.5E-16 T 29-03-2018 CXR48_RS02755 962b666ac8bad00ea2bd15441f24e5ab 396 Gene3D G3DSA:1.20.1250.20 14 199 1.3E-19 T 29-03-2018 CXR48_RS02755 962b666ac8bad00ea2bd15441f24e5ab 396 SUPERFAMILY SSF103473 15 392 1.83E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15925 cb7554abd6233a1e8f2c702652b727a9 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 198 4.8E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15925 cb7554abd6233a1e8f2c702652b727a9 217 SUPERFAMILY SSF161098 13 198 4.45E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15925 cb7554abd6233a1e8f2c702652b727a9 217 Gene3D G3DSA:1.10.3720.10 3 210 9.4E-33 T 29-03-2018 CXR48_RS15030 cf93f5926bd9a1e694eaf4ab32495cd9 405 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 194 404 1.5E-75 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CXR48_RS15030 cf93f5926bd9a1e694eaf4ab32495cd9 405 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 6 404 5.3E-145 T 29-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 CXR48_RS15030 cf93f5926bd9a1e694eaf4ab32495cd9 405 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 3.5E-25 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CXR48_RS15720 ad50f2b2f1607af1766ba510bfd8ce4d 139 PIRSF PIRSF036659 1 139 6.4E-60 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC CXR48_RS15720 ad50f2b2f1607af1766ba510bfd8ce4d 139 Gene3D G3DSA:1.20.1550.10 1 135 4.6E-26 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CXR48_RS15720 ad50f2b2f1607af1766ba510bfd8ce4d 139 Pfam PF02600 Disulfide bond formation protein DsbB 12 126 2.6E-8 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CXR48_RS15720 ad50f2b2f1607af1766ba510bfd8ce4d 139 SUPERFAMILY SSF158442 8 131 5.36E-30 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CXR48_RS15720 ad50f2b2f1607af1766ba510bfd8ce4d 139 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 1 136 24.571 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC CXR48_RS06800 bd6df865ff9f8250d4b5b72358302c7b 219 SUPERFAMILY SSF52402 3 211 2.65E-66 T 29-03-2018 CXR48_RS06800 bd6df865ff9f8250d4b5b72358302c7b 219 Gene3D G3DSA:3.40.50.620 3 218 1.9E-53 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS06800 bd6df865ff9f8250d4b5b72358302c7b 219 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 216 50.648 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CXR48_RS06800 bd6df865ff9f8250d4b5b72358302c7b 219 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 204 6.5E-89 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CXR48_RS06800 bd6df865ff9f8250d4b5b72358302c7b 219 Pfam PF06508 Queuosine biosynthesis protein QueC 5 211 3.8E-87 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CXR48_RS06800 bd6df865ff9f8250d4b5b72358302c7b 219 PIRSF PIRSF006293 2 217 3.6E-79 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CXR48_RS15855 8ddd60cdb70b5a06dfd94db46c3fa403 143 SMART SM00530 7 63 1.1E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS15855 8ddd60cdb70b5a06dfd94db46c3fa403 143 Pfam PF13560 Helix-turn-helix domain 4 62 1.6E-15 T 29-03-2018 CXR48_RS15855 8ddd60cdb70b5a06dfd94db46c3fa403 143 SUPERFAMILY SSF47413 3 66 6.47E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS15855 8ddd60cdb70b5a06dfd94db46c3fa403 143 Gene3D G3DSA:1.10.260.40 1 138 2.3E-24 T 29-03-2018 CXR48_RS15175 0ba4c4fbbcbc39be596a559e52924c75 413 PIRSF PIRSF001235 7 413 3.7E-139 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CXR48_RS15175 0ba4c4fbbcbc39be596a559e52924c75 413 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 13 410 7.1E-134 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CXR48_RS15175 0ba4c4fbbcbc39be596a559e52924c75 413 Gene3D G3DSA:3.40.630.10 4 246 1.1E-34 T 29-03-2018 CXR48_RS15175 0ba4c4fbbcbc39be596a559e52924c75 413 Pfam PF01546 Peptidase family M20/M25/M40 81 409 3.5E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS15175 0ba4c4fbbcbc39be596a559e52924c75 413 SUPERFAMILY SSF53187 339 412 5.09E-80 T 29-03-2018 CXR48_RS15175 0ba4c4fbbcbc39be596a559e52924c75 413 SUPERFAMILY SSF53187 15 226 5.09E-80 T 29-03-2018 CXR48_RS15175 0ba4c4fbbcbc39be596a559e52924c75 413 SUPERFAMILY SSF55031 216 332 1.66E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS15175 0ba4c4fbbcbc39be596a559e52924c75 413 Gene3D G3DSA:3.40.630.10 247 413 8.6E-23 T 29-03-2018 CXR48_RS00570 13e572a75eb7deca760de926535e1387 185 Gene3D G3DSA:3.30.60.20 2 119 0.0028 T 29-03-2018 CXR48_RS00570 13e572a75eb7deca760de926535e1387 185 Pfam PF02151 UvrB/uvrC motif 145 174 1.5E-6 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS00570 13e572a75eb7deca760de926535e1387 185 Gene3D G3DSA:4.10.860.10 120 178 2.8E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS00570 13e572a75eb7deca760de926535e1387 185 PIRSF PIRSF015034 1 182 4.1E-74 T 29-03-2018 IPR025542 YacH protein CXR48_RS00570 13e572a75eb7deca760de926535e1387 185 SUPERFAMILY SSF46600 140 175 7.72E-6 T 29-03-2018 IPR001943 UVR domain GO:0005515 CXR48_RS08775 3ecc67a54b6f1d6f6fa3b8750353ac50 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 4.7E-28 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS08775 3ecc67a54b6f1d6f6fa3b8750353ac50 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CXR48_RS08775 3ecc67a54b6f1d6f6fa3b8750353ac50 338 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 165 193 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CXR48_RS08775 3ecc67a54b6f1d6f6fa3b8750353ac50 338 SMART SM00829 8 334 3.4E-8 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS08775 3ecc67a54b6f1d6f6fa3b8750353ac50 338 Pfam PF00107 Zinc-binding dehydrogenase 172 300 5.6E-30 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS08775 3ecc67a54b6f1d6f6fa3b8750353ac50 338 Gene3D G3DSA:3.90.180.10 1 145 7.5E-43 T 29-03-2018 CXR48_RS08775 3ecc67a54b6f1d6f6fa3b8750353ac50 338 Gene3D G3DSA:3.40.50.720 146 329 3.2E-37 T 29-03-2018 CXR48_RS08775 3ecc67a54b6f1d6f6fa3b8750353ac50 338 SUPERFAMILY SSF50129 2 155 5.17E-46 T 29-03-2018 IPR011032 GroES-like CXR48_RS08775 3ecc67a54b6f1d6f6fa3b8750353ac50 338 SUPERFAMILY SSF51735 134 304 1.91E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08840 fbe6e21b67b63739b15e55773e3f8f29 144 Pfam PF00692 dUTPase 27 141 1.2E-14 T 29-03-2018 IPR029054 dUTPase-like CXR48_RS08840 fbe6e21b67b63739b15e55773e3f8f29 144 SUPERFAMILY SSF51283 16 143 4.32E-26 T 29-03-2018 IPR029054 dUTPase-like CXR48_RS08840 fbe6e21b67b63739b15e55773e3f8f29 144 Gene3D G3DSA:2.70.40.10 1 144 7.2E-38 T 29-03-2018 CXR48_RS19290 27f4239f3b4e4077a4252250cf024a11 155 Pfam PF02556 Preprotein translocase subunit SecB 110 149 5.1E-5 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CXR48_RS19290 27f4239f3b4e4077a4252250cf024a11 155 SUPERFAMILY SSF54611 80 149 2.11E-12 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CXR48_RS19290 27f4239f3b4e4077a4252250cf024a11 155 Gene3D G3DSA:3.10.420.10 9 155 7.2E-25 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CXR48_RS00110 442806200328cd7bf93a0cca3de8eb68 207 Gene3D G3DSA:3.40.50.300 1 204 7.6E-42 T 29-03-2018 CXR48_RS00110 442806200328cd7bf93a0cca3de8eb68 207 Pfam PF01712 Deoxynucleoside kinase 7 207 5.3E-57 T 29-03-2018 IPR031314 Deoxynucleoside kinase domain CXR48_RS00110 442806200328cd7bf93a0cca3de8eb68 207 SUPERFAMILY SSF52540 1 205 2.52E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00110 442806200328cd7bf93a0cca3de8eb68 207 PIRSF PIRSF000705 1 207 5.9E-58 T 29-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CXR48_RS10290 00a7c2d4836311bfacfe69090b2a7c4a 100 Gene3D G3DSA:1.10.3230.10 5 97 6.5E-5 T 29-03-2018 CXR48_RS10290 00a7c2d4836311bfacfe69090b2a7c4a 100 Pfam PF05135 Phage gp6-like head-tail connector protein 7 83 3.7E-14 T 29-03-2018 IPR021146 Phage gp6-like head-tail connector protein CXR48_RS10290 00a7c2d4836311bfacfe69090b2a7c4a 100 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 9 89 2.6E-14 T 29-03-2018 IPR006450 Phage protein of unkonwn function CXR48_RS06935 ed1841f6fb35c658acfbac69bca4178e 154 Pfam PF14177 YkyB-like protein 13 150 4.5E-69 T 29-03-2018 IPR025552 YkyB-like protein CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 Gene3D G3DSA:3.40.50.2300 55 173 5.1E-22 T 29-03-2018 CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 SUPERFAMILY SSF53822 61 329 1.45E-69 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 Gene3D G3DSA:1.10.260.40 2 54 4.0E-22 T 29-03-2018 CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 SUPERFAMILY SSF47413 1 59 8.94E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 SMART SM00354 1 71 2.2E-30 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.0E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.0E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 Gene3D G3DSA:3.40.50.2300 174 311 3.7E-40 T 29-03-2018 CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 Pfam PF13377 Periplasmic binding protein-like domain 168 327 3.5E-33 T 29-03-2018 CXR48_RS06085 e2212336cd3a0a9d3554fcb8c7aef0f5 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.7E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CXR48_RS07825 5b6e1bd680cf1ac542d41de2b510761b 406 Gene3D G3DSA:3.40.50.10300 184 404 9.4E-67 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CXR48_RS07825 5b6e1bd680cf1ac542d41de2b510761b 406 Pfam PF02441 Flavoprotein 5 177 1.2E-46 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CXR48_RS07825 5b6e1bd680cf1ac542d41de2b510761b 406 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 395 8.9E-157 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CXR48_RS07825 5b6e1bd680cf1ac542d41de2b510761b 406 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 369 1.2E-70 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CXR48_RS07825 5b6e1bd680cf1ac542d41de2b510761b 406 SUPERFAMILY SSF52507 2 178 3.4E-62 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CXR48_RS07825 5b6e1bd680cf1ac542d41de2b510761b 406 SUPERFAMILY SSF102645 186 397 1.16E-71 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CXR48_RS07825 5b6e1bd680cf1ac542d41de2b510761b 406 Gene3D G3DSA:3.40.50.1950 1 183 1.3E-56 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CXR48_RS12245 91f9c1c20c21d104a3a6b6f205647aed 343 SUPERFAMILY SSF55781 71 340 4.9E-71 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS12245 91f9c1c20c21d104a3a6b6f205647aed 343 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 336 4.2E-119 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CXR48_RS12245 91f9c1c20c21d104a3a6b6f205647aed 343 PIRSF PIRSF005485 1 341 5.7E-128 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CXR48_RS12245 91f9c1c20c21d104a3a6b6f205647aed 343 Pfam PF01628 HrcA protein C terminal domain 104 323 2.7E-66 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CXR48_RS12245 91f9c1c20c21d104a3a6b6f205647aed 343 SUPERFAMILY SSF46785 1 84 5.57E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12245 91f9c1c20c21d104a3a6b6f205647aed 343 Gene3D G3DSA:1.10.10.10 1 85 7.2E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12245 91f9c1c20c21d104a3a6b6f205647aed 343 Gene3D G3DSA:3.30.450.40 188 343 1.6E-41 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS12245 91f9c1c20c21d104a3a6b6f205647aed 343 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 330 33.778 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CXR48_RS17635 2c4651eca94d66c1cab6322fd6541eae 158 Gene3D G3DSA:2.60.120.10 8 141 2.5E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS17635 2c4651eca94d66c1cab6322fd6541eae 158 SUPERFAMILY SSF51206 47 142 5.89E-11 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CXR48_RS00900 b7c08a0ca5380579cf32b4a561ef8ee6 247 Gene3D G3DSA:3.30.70.660 107 244 7.0E-43 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS00900 b7c08a0ca5380579cf32b4a561ef8ee6 247 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 245 36.372 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS00900 b7c08a0ca5380579cf32b4a561ef8ee6 247 PIRSF PIRSF001430 1 247 4.4E-84 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS00900 b7c08a0ca5380579cf32b4a561ef8ee6 247 SUPERFAMILY SSF55120 1 247 2.16E-87 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS00900 b7c08a0ca5380579cf32b4a561ef8ee6 247 Gene3D G3DSA:3.30.70.580 1 106 3.8E-31 T 29-03-2018 CXR48_RS00900 b7c08a0ca5380579cf32b4a561ef8ee6 247 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 240 3.3E-74 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS00900 b7c08a0ca5380579cf32b4a561ef8ee6 247 Pfam PF01416 tRNA pseudouridine synthase 8 104 4.9E-8 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS00900 b7c08a0ca5380579cf32b4a561ef8ee6 247 Pfam PF01416 tRNA pseudouridine synthase 144 246 6.4E-33 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 SUPERFAMILY SSF46894 152 227 2.07E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 SMART SM00448 4 117 9.1E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 Gene3D G3DSA:3.40.50.2300 3 128 6.9E-33 T 29-03-2018 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 SMART SM00421 163 220 9.7E-29 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 SUPERFAMILY SSF52172 3 136 2.13E-34 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 Pfam PF00072 Response regulator receiver domain 6 118 5.3E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 1.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 1.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 1.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 Gene3D G3DSA:1.10.10.10 129 229 2.2E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16715 32b0f2c6870e6e489d3114c473f9d31f 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 220 7.9E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS06205 c0bf46e03beaaa563bb27281997f05e2 275 Gene3D G3DSA:1.10.10.10 34 123 1.8E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06205 c0bf46e03beaaa563bb27281997f05e2 275 SUPERFAMILY SSF46785 52 102 8.06E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05545 49e2fefc5bb8b49eed2c547d97c8fc71 317 SUPERFAMILY SSF53822 25 266 3.59E-18 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS05545 49e2fefc5bb8b49eed2c547d97c8fc71 317 Gene3D G3DSA:3.40.50.2300 143 312 2.6E-27 T 29-03-2018 CXR48_RS05545 49e2fefc5bb8b49eed2c547d97c8fc71 317 Gene3D G3DSA:3.40.50.2300 28 142 2.3E-22 T 29-03-2018 CXR48_RS05545 49e2fefc5bb8b49eed2c547d97c8fc71 317 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 27 317 1.1E-74 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CXR48_RS09375 c5a990911930e67d37caa1e8e144ecab 488 Gene3D G3DSA:3.30.420.40 1 242 2.3E-45 T 29-03-2018 CXR48_RS09375 c5a990911930e67d37caa1e8e144ecab 488 Gene3D G3DSA:3.30.420.40 243 488 4.9E-25 T 29-03-2018 CXR48_RS09375 c5a990911930e67d37caa1e8e144ecab 488 SUPERFAMILY SSF53067 250 461 5.47E-27 T 29-03-2018 CXR48_RS09375 c5a990911930e67d37caa1e8e144ecab 488 PIRSF PIRSF000538 4 487 2.6E-66 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CXR48_RS09375 c5a990911930e67d37caa1e8e144ecab 488 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 243 1.7E-37 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CXR48_RS09375 c5a990911930e67d37caa1e8e144ecab 488 SUPERFAMILY SSF53067 7 244 6.79E-43 T 29-03-2018 CXR48_RS09375 c5a990911930e67d37caa1e8e144ecab 488 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 345 440 1.7E-11 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CXR48_RS12200 b991afcd0a1c12ba617930510c3c167a 148 Pfam PF09424 Yqey-like protein 5 147 2.3E-52 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CXR48_RS12200 b991afcd0a1c12ba617930510c3c167a 148 SUPERFAMILY SSF89095 1 147 1.2E-41 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CXR48_RS12200 b991afcd0a1c12ba617930510c3c167a 148 Gene3D G3DSA:1.10.1510.10 1 91 1.1E-25 T 29-03-2018 CXR48_RS12200 b991afcd0a1c12ba617930510c3c167a 148 Gene3D G3DSA:1.10.10.410 92 148 5.9E-21 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CXR48_RS11815 77e84a468fa0467c91862d58aab2f245 57 Pfam PF08671 Anti-repressor SinI 11 37 1.4E-11 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CXR48_RS11815 77e84a468fa0467c91862d58aab2f245 57 Gene3D G3DSA:1.10.1660.10 11 54 3.9E-4 T 29-03-2018 CXR48_RS11815 77e84a468fa0467c91862d58aab2f245 57 SUPERFAMILY SSF47406 10 39 7.46E-13 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CXR48_RS04960 61cc02b5f2ad5ce39ef508c705188d35 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 5 26 3.5E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS04960 61cc02b5f2ad5ce39ef508c705188d35 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 5 27 7.7E-13 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS00330 b4ef2f746944e48ad9ef0f8626596420 188 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 186 1.0E-72 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CXR48_RS00330 b4ef2f746944e48ad9ef0f8626596420 188 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 1.0E-57 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CXR48_RS00330 b4ef2f746944e48ad9ef0f8626596420 188 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 36.521 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CXR48_RS00330 b4ef2f746944e48ad9ef0f8626596420 188 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CXR48_RS00330 b4ef2f746944e48ad9ef0f8626596420 188 Gene3D G3DSA:3.40.50.1470 1 188 3.8E-72 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CXR48_RS00330 b4ef2f746944e48ad9ef0f8626596420 188 SUPERFAMILY SSF53178 1 185 3.53E-68 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CXR48_RS00330 b4ef2f746944e48ad9ef0f8626596420 188 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CXR48_RS08435 da32bd00632039acae6fd3405e4d942e 296 Pfam PF13464 Domain of unknown function (DUF4115) 216 276 3.5E-11 T 29-03-2018 IPR025194 Domain of unknown function DUF4115 CXR48_RS08435 da32bd00632039acae6fd3405e4d942e 296 Gene3D G3DSA:1.10.260.40 1 83 9.0E-13 T 29-03-2018 CXR48_RS08435 da32bd00632039acae6fd3405e4d942e 296 SUPERFAMILY SSF47413 3 75 6.52E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS08435 da32bd00632039acae6fd3405e4d942e 296 Pfam PF13413 Helix-turn-helix domain 7 67 2.9E-23 T 29-03-2018 CXR48_RS08435 da32bd00632039acae6fd3405e4d942e 296 SMART SM00530 7 68 6.1E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS05850 f624a2b9016eb9ba59c8a92fcd17825f 171 Hamap MF_01444 Putative phosphoesterase . 1 168 39.562 T 29-03-2018 IPR022932 Putative phosphoesterase YjcG CXR48_RS05850 f624a2b9016eb9ba59c8a92fcd17825f 171 SUPERFAMILY SSF55144 1 170 3.84E-34 T 29-03-2018 IPR009097 Cyclic phosphodiesterase CXR48_RS05850 f624a2b9016eb9ba59c8a92fcd17825f 171 Pfam PF13563 2'-5' RNA ligase superfamily 11 153 2.0E-21 T 29-03-2018 CXR48_RS05850 f624a2b9016eb9ba59c8a92fcd17825f 171 Gene3D G3DSA:3.90.1140.10 1 171 2.0E-28 T 29-03-2018 CXR48_RS12540 291f065e33d8cdfb33e5c7c223a4aa07 307 SUPERFAMILY SSF53686 3 302 1.83E-91 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS12540 291f065e33d8cdfb33e5c7c223a4aa07 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CXR48_RS12540 291f065e33d8cdfb33e5c7c223a4aa07 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 4.5E-66 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS12540 291f065e33d8cdfb33e5c7c223a4aa07 307 Gene3D G3DSA:3.40.50.1100 41 139 8.1E-31 T 29-03-2018 CXR48_RS12540 291f065e33d8cdfb33e5c7c223a4aa07 307 Gene3D G3DSA:3.40.50.1100 140 306 1.9E-51 T 29-03-2018 CXR48_RS13805 286fe352b066d419073e7d3a8e3e2263 108 Gene3D G3DSA:3.40.30.10 3 105 8.0E-37 T 29-03-2018 CXR48_RS13805 286fe352b066d419073e7d3a8e3e2263 108 SUPERFAMILY SSF52833 5 107 8.33E-11 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS13805 286fe352b066d419073e7d3a8e3e2263 108 Pfam PF11009 Protein of unknown function (DUF2847) 6 103 4.7E-36 T 29-03-2018 IPR022551 Protein of unknown function DUF2847 CXR48_RS13805 286fe352b066d419073e7d3a8e3e2263 108 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 6 105 1.8E-37 T 29-03-2018 IPR022551 Protein of unknown function DUF2847 CXR48_RS02730 7102d497cc34a76d5e2dfa1a8fb3acd9 134 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS02730 7102d497cc34a76d5e2dfa1a8fb3acd9 134 Gene3D G3DSA:1.10.1660.10 57 131 2.9E-11 T 29-03-2018 CXR48_RS02730 7102d497cc34a76d5e2dfa1a8fb3acd9 134 Pfam PF13411 MerR HTH family regulatory protein 1 66 1.8E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS02730 7102d497cc34a76d5e2dfa1a8fb3acd9 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.3E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS02730 7102d497cc34a76d5e2dfa1a8fb3acd9 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.3E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS02730 7102d497cc34a76d5e2dfa1a8fb3acd9 134 Gene3D G3DSA:1.10.1660.10 1 56 9.5E-22 T 29-03-2018 CXR48_RS02730 7102d497cc34a76d5e2dfa1a8fb3acd9 134 SUPERFAMILY SSF46955 1 120 4.4E-29 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS02730 7102d497cc34a76d5e2dfa1a8fb3acd9 134 SMART SM00422 1 70 1.9E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS19330 cd3ad4188b3202644935d3eac56df1fc 252 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 249 2.6E-103 T 29-03-2018 CXR48_RS19330 cd3ad4188b3202644935d3eac56df1fc 252 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CXR48_RS19330 cd3ad4188b3202644935d3eac56df1fc 252 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 243 8.7E-28 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CXR48_RS19330 cd3ad4188b3202644935d3eac56df1fc 252 Gene3D G3DSA:3.60.10.10 1 252 7.8E-60 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CXR48_RS19330 cd3ad4188b3202644935d3eac56df1fc 252 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 5.3E-103 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CXR48_RS19330 cd3ad4188b3202644935d3eac56df1fc 252 SUPERFAMILY SSF56219 1 251 4.45E-83 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CXR48_RS00400 d8c1ecec0ff6cfccad4a6214b7a4a6b7 245 Gene3D G3DSA:3.40.50.410 2 129 1.0E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS00400 d8c1ecec0ff6cfccad4a6214b7a4a6b7 245 SUPERFAMILY SSF53300 3 71 2.37E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS00400 d8c1ecec0ff6cfccad4a6214b7a4a6b7 245 Gene3D G3DSA:3.40.50.410 133 235 1.2E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS00400 d8c1ecec0ff6cfccad4a6214b7a4a6b7 245 SUPERFAMILY SSF53300 133 226 1.93E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS00400 d8c1ecec0ff6cfccad4a6214b7a4a6b7 245 Pfam PF00092 von Willebrand factor type A domain 7 77 2.3E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS18845 f57186671cbb87d3b81fd8e98594fd5b 280 Gene3D G3DSA:3.30.390.50 178 276 6.5E-13 T 29-03-2018 CXR48_RS18845 f57186671cbb87d3b81fd8e98594fd5b 280 SMART SM01092 179 274 9.4E-10 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CXR48_RS18845 f57186671cbb87d3b81fd8e98594fd5b 280 SUPERFAMILY SSF55447 178 277 8.37E-14 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CXR48_RS18845 f57186671cbb87d3b81fd8e98594fd5b 280 Gene3D G3DSA:3.30.43.10 1 57 6.9E-13 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CXR48_RS18845 f57186671cbb87d3b81fd8e98594fd5b 280 SUPERFAMILY SSF56176 1 169 7.2E-32 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS18845 f57186671cbb87d3b81fd8e98594fd5b 280 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 168 1.2E-24 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CXR48_RS18845 f57186671cbb87d3b81fd8e98594fd5b 280 Gene3D G3DSA:3.30.465.10 63 169 3.3E-11 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS03895 96744e68a77fde97d29bc94646ebcc78 351 TIGRFAM TIGR00378 cax: calcium/proton exchanger 12 349 9.2E-164 T 29-03-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 CXR48_RS03895 96744e68a77fde97d29bc94646ebcc78 351 Pfam PF01699 Sodium/calcium exchanger protein 207 346 3.2E-18 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CXR48_RS03895 96744e68a77fde97d29bc94646ebcc78 351 Pfam PF01699 Sodium/calcium exchanger protein 26 178 1.4E-22 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CXR48_RS03895 96744e68a77fde97d29bc94646ebcc78 351 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 2 349 1.9E-131 T 29-03-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 CXR48_RS17610 2af44a84838b45d306e756c61c685002 209 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 4 185 2.6E-35 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 Pfam PF11962 Peptidase_G2, IMC autoproteolytic cleavage domain 593 805 1.9E-71 T 29-03-2018 IPR021865 Peptidase G2, IMC autoproteolytic cleavage domain CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 Gene3D G3DSA:4.10.80.40 701 719 5.8E-13 T 29-03-2018 CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 SUPERFAMILY SSF51126 79 369 2.15E-34 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 Gene3D G3DSA:2.160.10.20 514 633 2.5E-39 T 29-03-2018 CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 Gene3D G3DSA:2.40.300.10 720 797 2.7E-22 T 29-03-2018 CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 Gene3D G3DSA:2.40.300.10 639 700 2.6E-15 T 29-03-2018 CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 Gene3D G3DSA:2.160.20.10 73 513 2.7E-67 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 Pfam PF12708 Pectate lyase superfamily protein 82 310 5.9E-19 T 29-03-2018 IPR024535 Pectate lyase superfamily protein CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 SMART SM00710 419 440 66.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 SMART SM00710 199 221 220.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 SMART SM00710 294 315 350.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 SMART SM00710 237 259 26.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 SMART SM00710 357 383 6000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 SMART SM00710 448 470 1700.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS08830 15ab99692067b68fe6d4427867440f00 805 SMART SM00710 260 292 1000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS19020 e6dd04d93a16a1076cef08e32b28b15d 452 Pfam PF07435 YycH protein 4 452 5.0E-140 T 29-03-2018 IPR009996 Regulatory protein YycH CXR48_RS15575 3edea8b45940c3c783e2995ed254d567 386 SMART SM00835 230 372 3.5E-32 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS15575 3edea8b45940c3c783e2995ed254d567 386 SMART SM00835 55 194 1.8E-20 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS15575 3edea8b45940c3c783e2995ed254d567 386 Gene3D G3DSA:2.60.120.10 218 386 4.0E-37 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS15575 3edea8b45940c3c783e2995ed254d567 386 Gene3D G3DSA:2.60.120.10 3 210 1.5E-52 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS15575 3edea8b45940c3c783e2995ed254d567 386 SUPERFAMILY SSF51182 11 381 2.6E-104 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS15575 3edea8b45940c3c783e2995ed254d567 386 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 16 382 3.2E-180 T 29-03-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 CXR48_RS15575 3edea8b45940c3c783e2995ed254d567 386 Pfam PF00190 Cupin 231 368 6.0E-29 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS15575 3edea8b45940c3c783e2995ed254d567 386 Pfam PF00190 Cupin 63 191 9.6E-25 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CXR48_RS03370 cc0588d0dffb57cfd474a1373827b1bf 398 PIRSF PIRSF012509 2 398 3.8E-161 T 29-03-2018 IPR011426 CamS sex pheromone cAM373 CXR48_RS03370 cc0588d0dffb57cfd474a1373827b1bf 398 Pfam PF07537 CamS sex pheromone cAM373 precursor 62 391 2.2E-127 T 29-03-2018 IPR011426 CamS sex pheromone cAM373 CXR48_RS03370 cc0588d0dffb57cfd474a1373827b1bf 398 Gene3D G3DSA:3.10.570.10 41 398 7.2E-136 T 29-03-2018 CXR48_RS18860 c6fdc6cda08986f3350fbcb75d7009ab 337 Pfam PF13478 XdhC Rossmann domain 191 326 2.2E-30 T 29-03-2018 IPR027051 XdhC Rossmann domain CXR48_RS18860 c6fdc6cda08986f3350fbcb75d7009ab 337 Pfam PF02625 XdhC and CoxI family 13 78 5.5E-16 T 29-03-2018 IPR003777 XdhC- CoxI CXR48_RS18860 c6fdc6cda08986f3350fbcb75d7009ab 337 Gene3D G3DSA:3.40.50.20 191 282 0.0014 T 29-03-2018 CXR48_RS02100 962915c7d2294587a57e707c58794750 264 SUPERFAMILY SSF160920 4 256 1.05E-114 T 29-03-2018 CXR48_RS02100 962915c7d2294587a57e707c58794750 264 PIRSF PIRSF029755 1 264 1.7E-127 T 29-03-2018 IPR016938 Uncharacterised protein family UPF0317 CXR48_RS02100 962915c7d2294587a57e707c58794750 264 Hamap MF_01830 UPF0317 protein . 9 263 54.541 T 29-03-2018 IPR016938 Uncharacterised protein family UPF0317 CXR48_RS02100 962915c7d2294587a57e707c58794750 264 Gene3D G3DSA:3.40.1640.10 200 264 3.3E-11 T 29-03-2018 CXR48_RS02100 962915c7d2294587a57e707c58794750 264 Gene3D G3DSA:3.40.1640.10 1 165 3.4E-68 T 29-03-2018 CXR48_RS02100 962915c7d2294587a57e707c58794750 264 Pfam PF07286 Protein of unknown function (DUF1445) 113 255 6.4E-68 T 29-03-2018 IPR009906 D-glutamate cyclase CXR48_RS11210 6008b1fa2ac69a870ba15613327b5fda 184 Gene3D G3DSA:3.90.79.10 3 184 3.1E-45 T 29-03-2018 CXR48_RS11210 6008b1fa2ac69a870ba15613327b5fda 184 Pfam PF00293 NUDIX domain 42 156 1.3E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CXR48_RS11210 6008b1fa2ac69a870ba15613327b5fda 184 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CXR48_RS11210 6008b1fa2ac69a870ba15613327b5fda 184 PRINTS PR00502 NUDIX hydrolase family signature 72 86 1.1E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS11210 6008b1fa2ac69a870ba15613327b5fda 184 PRINTS PR00502 NUDIX hydrolase family signature 86 101 1.1E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CXR48_RS11210 6008b1fa2ac69a870ba15613327b5fda 184 SUPERFAMILY SSF55811 7 177 7.58E-51 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CXR48_RS00415 114cd2b4562a8eb61ac0667fc11816a0 179 SUPERFAMILY SSF53271 3 178 8.26E-60 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS00415 114cd2b4562a8eb61ac0667fc11816a0 179 Pfam PF00156 Phosphoribosyl transferase domain 14 159 8.3E-25 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CXR48_RS00415 114cd2b4562a8eb61ac0667fc11816a0 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 173 3.1E-71 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CXR48_RS00415 114cd2b4562a8eb61ac0667fc11816a0 179 Gene3D G3DSA:3.40.50.2020 1 179 8.9E-48 T 29-03-2018 CXR48_RS12065 62f14fdc549739931b4f331f0058fbe3 297 SMART SM00518 3 285 2.0E-133 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CXR48_RS12065 62f14fdc549739931b4f331f0058fbe3 297 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 282 8.3E-105 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CXR48_RS12065 62f14fdc549739931b4f331f0058fbe3 297 Pfam PF01261 Xylose isomerase-like TIM barrel 21 237 2.0E-38 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS12065 62f14fdc549739931b4f331f0058fbe3 297 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CXR48_RS12065 62f14fdc549739931b4f331f0058fbe3 297 Gene3D G3DSA:3.20.20.150 1 297 1.3E-58 T 29-03-2018 CXR48_RS12065 62f14fdc549739931b4f331f0058fbe3 297 SUPERFAMILY SSF51658 2 294 2.62E-101 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS12065 62f14fdc549739931b4f331f0058fbe3 297 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CXR48_RS12065 62f14fdc549739931b4f331f0058fbe3 297 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 42.287 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CXR48_RS12065 62f14fdc549739931b4f331f0058fbe3 297 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CXR48_RS07550 854d512436b94e154fab41b74dc984fb 311 Pfam PF01795 MraW methylase family 2 310 7.2E-138 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS07550 854d512436b94e154fab41b74dc984fb 311 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 2.9E-136 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS07550 854d512436b94e154fab41b74dc984fb 311 PIRSF PIRSF004486 1 311 3.8E-111 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS07550 854d512436b94e154fab41b74dc984fb 311 Gene3D G3DSA:3.40.50.150 170 311 2.3E-23 T 29-03-2018 CXR48_RS07550 854d512436b94e154fab41b74dc984fb 311 Gene3D G3DSA:3.40.50.150 4 169 1.5E-17 T 29-03-2018 CXR48_RS07550 854d512436b94e154fab41b74dc984fb 311 SUPERFAMILY SSF81799 113 214 1.44E-36 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS07550 854d512436b94e154fab41b74dc984fb 311 SUPERFAMILY SSF53335 4 112 4.64E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS07550 854d512436b94e154fab41b74dc984fb 311 SUPERFAMILY SSF53335 214 309 4.64E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS07550 854d512436b94e154fab41b74dc984fb 311 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 39.34 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CXR48_RS00930 3dc9e6609884ade678337b5e61c2d19f 237 Gene3D G3DSA:3.40.630.40 38 234 2.4E-56 T 29-03-2018 CXR48_RS00930 3dc9e6609884ade678337b5e61c2d19f 237 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 43 226 1.6E-47 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS00930 3dc9e6609884ade678337b5e61c2d19f 237 SMART SM00646 115 226 8.3E-36 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS00930 3dc9e6609884ade678337b5e61c2d19f 237 SUPERFAMILY SSF53187 41 230 2.01E-51 T 29-03-2018 CXR48_RS00930 3dc9e6609884ade678337b5e61c2d19f 237 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 41 228 2.6E-84 T 29-03-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD CXR48_RS10230 767ed415a308690711bcb22f99bfa978 61 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 4 45 1.4E-12 T 29-03-2018 IPR010022 Protein of unknown function XkdX CXR48_RS10230 767ed415a308690711bcb22f99bfa978 61 TIGRFAM TIGR01669 phage_XkdX: phage uncharacterized protein, XkdX family 1 45 7.8E-23 T 29-03-2018 IPR010022 Protein of unknown function XkdX CXR48_RS09310 d7905dfa19eaea00351d1bd7ace90133 98 SUPERFAMILY SSF52954 20 91 3.78E-16 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS09310 d7905dfa19eaea00351d1bd7ace90133 98 Pfam PF03129 Anticodon binding domain 20 86 3.1E-13 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS09310 d7905dfa19eaea00351d1bd7ace90133 98 Gene3D G3DSA:3.40.50.800 17 97 4.4E-14 T 29-03-2018 IPR004154 Anticodon-binding CXR48_RS14745 139a0eb2a4534ee0343c7cd8f4f93b94 127 Gene3D G3DSA:3.10.129.10 1 125 1.6E-27 T 29-03-2018 CXR48_RS14745 139a0eb2a4534ee0343c7cd8f4f93b94 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 7 124 1.4E-41 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CXR48_RS14745 139a0eb2a4534ee0343c7cd8f4f93b94 127 SUPERFAMILY SSF54637 5 125 6.08E-31 T 29-03-2018 IPR029069 HotDog domain CXR48_RS14745 139a0eb2a4534ee0343c7cd8f4f93b94 127 Pfam PF03061 Thioesterase superfamily 37 116 7.6E-19 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CXR48_RS12070 1a5656b756e0206ed93986698be37cf2 438 SMART SM00487 23 223 2.8E-55 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS12070 1a5656b756e0206ed93986698be37cf2 438 SUPERFAMILY SSF52540 73 361 2.93E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12070 1a5656b756e0206ed93986698be37cf2 438 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 4 437 50.275 T 29-03-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 CXR48_RS12070 1a5656b756e0206ed93986698be37cf2 438 SMART SM00490 259 340 8.1E-31 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS12070 1a5656b756e0206ed93986698be37cf2 438 Gene3D G3DSA:3.40.50.300 3 222 1.3E-51 T 29-03-2018 CXR48_RS12070 1a5656b756e0206ed93986698be37cf2 438 Pfam PF00271 Helicase conserved C-terminal domain 236 340 3.7E-27 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS12070 1a5656b756e0206ed93986698be37cf2 438 Pfam PF00270 DEAD/DEAH box helicase 28 195 1.6E-43 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CXR48_RS12070 1a5656b756e0206ed93986698be37cf2 438 Gene3D G3DSA:3.40.50.300 223 438 1.4E-43 T 29-03-2018 CXR48_RS01295 7f7073c33680535bd349495e420b3ddd 156 Pfam PF01381 Helix-turn-helix 14 47 9.6E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS01295 7f7073c33680535bd349495e420b3ddd 156 SMART SM00530 13 68 2.8E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS01295 7f7073c33680535bd349495e420b3ddd 156 SUPERFAMILY SSF47413 6 63 5.09E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS01295 7f7073c33680535bd349495e420b3ddd 156 Gene3D G3DSA:1.10.260.40 12 89 4.2E-10 T 29-03-2018 CXR48_RS11455 6ea0007744bc12d11f9f8a6acb81f59e 278 Pfam PF02096 60Kd inner membrane protein 65 260 4.4E-48 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CXR48_RS11455 6ea0007744bc12d11f9f8a6acb81f59e 278 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 65 260 1.2E-51 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CXR48_RS11455 6ea0007744bc12d11f9f8a6acb81f59e 278 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 264 27.724 T 29-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CXR48_RS00430 67fb13928718c382d9aa52e52e148ccd 291 SUPERFAMILY SSF64397 1 239 2.22E-78 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CXR48_RS00430 67fb13928718c382d9aa52e52e148ccd 291 Gene3D G3DSA:3.55.30.10 1 232 3.5E-78 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CXR48_RS00430 67fb13928718c382d9aa52e52e148ccd 291 SUPERFAMILY SSF118352 229 288 2.62E-22 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CXR48_RS00430 67fb13928718c382d9aa52e52e148ccd 291 Pfam PF01430 Hsp33 protein 2 278 6.3E-91 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CXR48_RS00430 67fb13928718c382d9aa52e52e148ccd 291 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 289 41.202 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CXR48_RS00430 67fb13928718c382d9aa52e52e148ccd 291 PIRSF PIRSF005261 1 290 2.6E-77 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CXR48_RS00430 67fb13928718c382d9aa52e52e148ccd 291 Gene3D G3DSA:3.90.1280.10 233 286 7.9E-26 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CXR48_RS16645 87c0dde1b4f06ee05ed8602ae6ef3761 506 Gene3D G3DSA:3.90.20.10 385 503 7.6E-5 T 29-03-2018 CXR48_RS16645 87c0dde1b4f06ee05ed8602ae6ef3761 506 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 10 104 1.4E-23 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CXR48_RS16645 87c0dde1b4f06ee05ed8602ae6ef3761 506 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 225 492 4.2E-49 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CXR48_RS16645 87c0dde1b4f06ee05ed8602ae6ef3761 506 Pfam PF07196 Flagellin hook IN motif 123 185 3.2E-8 T 29-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 Pfam PF00406 Adenylate kinase 5 190 2.8E-62 T 29-03-2018 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 160 175 2.5E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 4 17 2.5E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 32 46 2.5E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 81 97 2.5E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 177 191 2.5E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 Hamap MF_00235 Adenylate kinase [adk]. 1 213 54.479 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 SUPERFAMILY SSF52540 1 213 1.15E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 8.6E-83 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 Gene3D G3DSA:3.40.50.300 1 217 1.3E-67 T 29-03-2018 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 Pfam PF05191 Adenylate kinase, active site lid 127 162 1.6E-16 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CXR48_RS00840 6bcda438bd750346da1fd82b5baff885 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CXR48_RS15140 3f206aaf4dbd59b1bda97d04987d7463 454 Gene3D G3DSA:3.20.20.140 70 393 1.9E-101 T 29-03-2018 CXR48_RS15140 3f206aaf4dbd59b1bda97d04987d7463 454 Pfam PF01979 Amidohydrolase family 51 426 7.0E-24 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CXR48_RS15140 3f206aaf4dbd59b1bda97d04987d7463 454 SUPERFAMILY SSF51338 375 444 3.11E-26 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS15140 3f206aaf4dbd59b1bda97d04987d7463 454 SUPERFAMILY SSF51338 3 54 3.11E-26 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS15140 3f206aaf4dbd59b1bda97d04987d7463 454 Hamap MF_01645 Allantoinase [allB]. 2 446 49.677 T 29-03-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 CXR48_RS15140 3f206aaf4dbd59b1bda97d04987d7463 454 Gene3D G3DSA:2.30.40.10 2 69 3.0E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS15140 3f206aaf4dbd59b1bda97d04987d7463 454 TIGRFAM TIGR03178 allantoinase: allantoinase 4 439 7.1E-175 T 29-03-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 CXR48_RS15140 3f206aaf4dbd59b1bda97d04987d7463 454 SUPERFAMILY SSF51556 55 376 2.86E-89 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS03210 731aa6531ac78d71942e2484f2ee33ea 320 Gene3D G3DSA:1.10.8.300 202 309 3.1E-34 T 29-03-2018 CXR48_RS03210 731aa6531ac78d71942e2484f2ee33ea 320 PIRSF PIRSF002849 2 315 3.2E-132 T 29-03-2018 CXR48_RS03210 731aa6531ac78d71942e2484f2ee33ea 320 SUPERFAMILY SSF52540 8 285 1.77E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03210 731aa6531ac78d71942e2484f2ee33ea 320 Gene3D G3DSA:3.40.50.300 22 188 5.5E-27 T 29-03-2018 CXR48_RS03210 731aa6531ac78d71942e2484f2ee33ea 320 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 3.2E-65 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CXR48_RS02550 cd1f4c247a411ff493a9fca7b9436bd6 315 SUPERFAMILY SSF53474 45 313 1.99E-68 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS02550 cd1f4c247a411ff493a9fca7b9436bd6 315 Pfam PF07859 alpha/beta hydrolase fold 81 289 2.0E-67 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CXR48_RS02550 cd1f4c247a411ff493a9fca7b9436bd6 315 Gene3D G3DSA:3.40.50.1820 3 315 1.5E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS04875 607436b84389dd93deb8d02546a3c685 379 SUPERFAMILY SSF48371 60 256 1.08E-47 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CXR48_RS04875 607436b84389dd93deb8d02546a3c685 379 Gene3D G3DSA:1.25.40.290 149 259 1.5E-21 T 29-03-2018 CXR48_RS04875 607436b84389dd93deb8d02546a3c685 379 Pfam PF08713 DNA alkylation repair enzyme 72 231 1.3E-4 T 29-03-2018 IPR014825 DNA alkylation repair enzyme CXR48_RS01100 cdecf697a51c106e6d2d667334eeda1c 479 Pfam PF07949 YbbR-like protein 55 135 5.7E-11 T 29-03-2018 IPR012505 YbbR-like CXR48_RS01100 cdecf697a51c106e6d2d667334eeda1c 479 Pfam PF07949 YbbR-like protein 143 228 1.5E-15 T 29-03-2018 IPR012505 YbbR-like CXR48_RS01100 cdecf697a51c106e6d2d667334eeda1c 479 Pfam PF07949 YbbR-like protein 239 316 2.2E-15 T 29-03-2018 IPR012505 YbbR-like CXR48_RS06810 f8f1d588ee5314bd3cb578683dc17c36 243 Pfam PF04055 Radical SAM superfamily 29 175 3.7E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS06810 f8f1d588ee5314bd3cb578683dc17c36 243 Pfam PF13394 4Fe-4S single cluster domain 27 114 6.1E-9 T 29-03-2018 CXR48_RS06810 f8f1d588ee5314bd3cb578683dc17c36 243 SUPERFAMILY SSF102114 27 152 6.8E-14 T 29-03-2018 CXR48_RS06810 f8f1d588ee5314bd3cb578683dc17c36 243 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 240 37.972 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CXR48_RS06810 f8f1d588ee5314bd3cb578683dc17c36 243 Gene3D G3DSA:3.80.30.20 22 200 7.3E-17 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CXR48_RS06810 f8f1d588ee5314bd3cb578683dc17c36 243 PIRSF PIRSF000370 3 243 9.4E-52 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CXR48_RS06810 f8f1d588ee5314bd3cb578683dc17c36 243 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 4 243 3.3E-117 T 29-03-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CXR48_RS02805 978a5df82253e5fdafac913dc2e0df0f 717 Pfam PF03176 MMPL family 45 360 1.7E-76 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CXR48_RS02805 978a5df82253e5fdafac913dc2e0df0f 717 Pfam PF03176 MMPL family 393 690 3.8E-37 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CXR48_RS02805 978a5df82253e5fdafac913dc2e0df0f 717 Gene3D G3DSA:1.20.1640.10 464 685 2.3E-34 T 29-03-2018 CXR48_RS02805 978a5df82253e5fdafac913dc2e0df0f 717 Gene3D G3DSA:1.20.1640.10 124 343 7.7E-31 T 29-03-2018 CXR48_RS02805 978a5df82253e5fdafac913dc2e0df0f 717 SUPERFAMILY SSF82866 455 686 2.88E-31 T 29-03-2018 CXR48_RS02805 978a5df82253e5fdafac913dc2e0df0f 717 SUPERFAMILY SSF82866 116 334 2.75E-25 T 29-03-2018 CXR48_RS11840 ff4882a64314b30fad65219ebb0f7479 109 Pfam PF13028 Protein of unknown function (DUF3889) 24 106 4.0E-28 T 29-03-2018 IPR024987 Protein of unknown function DUF3889 CXR48_RS15605 1c94f6f03c3e28ca3610d8e66bee0794 304 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 283 2.7E-41 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CXR48_RS15605 1c94f6f03c3e28ca3610d8e66bee0794 304 Gene3D G3DSA:3.40.50.150 4 289 1.3E-32 T 29-03-2018 CXR48_RS15605 1c94f6f03c3e28ca3610d8e66bee0794 304 SUPERFAMILY SSF53335 7 303 2.85E-55 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS15605 1c94f6f03c3e28ca3610d8e66bee0794 304 Pfam PF04072 Leucine carboxyl methyltransferase 11 206 1.2E-44 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CXR48_RS07960 91d58badbc8fad6ca92cbaf4ab6332d5 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 3 101 5.0E-42 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CXR48_RS07960 91d58badbc8fad6ca92cbaf4ab6332d5 110 SUPERFAMILY SSF88659 3 103 2.8E-33 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS07960 91d58badbc8fad6ca92cbaf4ab6332d5 110 Hamap MF_00245 UPF0122 protein . 3 103 22.288 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CXR48_RS07960 91d58badbc8fad6ca92cbaf4ab6332d5 110 Gene3D G3DSA:1.10.10.10 1 110 1.1E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05410 3d9cfe8b4e56d2bca8c3ed4b053cf9f6 163 SUPERFAMILY SSF89963 6 90 7.32E-29 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CXR48_RS05410 3d9cfe8b4e56d2bca8c3ed4b053cf9f6 163 Gene3D G3DSA:3.30.70.990 13 98 3.0E-29 T 29-03-2018 IPR035570 UPF0234 N-terminal domain CXR48_RS05410 3d9cfe8b4e56d2bca8c3ed4b053cf9f6 163 Gene3D G3DSA:3.30.70.860 99 163 9.4E-29 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain CXR48_RS05410 3d9cfe8b4e56d2bca8c3ed4b053cf9f6 163 SUPERFAMILY SSF89963 92 163 2.49E-26 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CXR48_RS05410 3d9cfe8b4e56d2bca8c3ed4b053cf9f6 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.015 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CXR48_RS05410 3d9cfe8b4e56d2bca8c3ed4b053cf9f6 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 1.7E-61 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CXR48_RS12765 03da58341aa963329a8505e408c84d6c 128 Pfam PF12670 Protein of unknown function (DUF3792) 10 119 6.8E-22 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CXR48_RS12765 03da58341aa963329a8505e408c84d6c 128 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 10 122 2.2E-28 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 SMART SM00955 248 578 2.7E-185 T 29-03-2018 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 SMART SM00357 73 133 3.5E-14 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 SMART SM00357 138 202 7.3E-11 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 TIGRFAM TIGR02063 RNase_R: ribonuclease R 9 708 7.2E-291 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 SUPERFAMILY SSF50249 626 705 7.55E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 SUPERFAMILY SSF50249 54 135 6.0E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 SMART SM00316 626 708 2.4E-20 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 Gene3D G3DSA:1.10.10.10 4 63 1.6E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 55 708 1.2E-278 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 Gene3D G3DSA:2.40.50.140 625 709 4.6E-24 T 29-03-2018 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 Hamap MF_01895 Ribonuclease R [rnr]. 25 708 62.607 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 Pfam PF08206 Ribonuclease B OB domain 148 201 2.9E-9 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 Pfam PF08206 Ribonuclease B OB domain 74 132 2.2E-20 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 ProSitePatterns PS01175 Ribonuclease II family signature. 545 569 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 Pfam PF00575 S1 RNA binding domain 625 707 2.3E-17 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 Pfam PF00773 RNB domain 248 576 4.8E-118 T 29-03-2018 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 SUPERFAMILY SSF50249 208 625 4.57E-150 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 Gene3D G3DSA:2.40.50.140 117 284 0.012 T 29-03-2018 CXR48_RS15830 cad9389eba06e4377a6e370035ddeeb5 777 SUPERFAMILY SSF50249 126 225 3.53E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS16970 89f6c3df41ed90649e28f21e8a5418d1 177 Gene3D G3DSA:2.30.30.410 29 115 6.0E-13 T 29-03-2018 CXR48_RS16970 89f6c3df41ed90649e28f21e8a5418d1 177 Pfam PF08239 Bacterial SH3 domain 56 107 7.6E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS16970 89f6c3df41ed90649e28f21e8a5418d1 177 Gene3D G3DSA:2.40.50.110 116 176 0.0043 T 29-03-2018 CXR48_RS16970 89f6c3df41ed90649e28f21e8a5418d1 177 SMART SM00287 47 111 2.5E-15 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS16970 89f6c3df41ed90649e28f21e8a5418d1 177 SMART SM00287 118 176 0.43 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS00575 34fd7f11144938d23daea078551e68fe 363 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 350 40.357 T 29-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 CXR48_RS00575 34fd7f11144938d23daea078551e68fe 363 SUPERFAMILY SSF55931 3 268 2.21E-87 T 29-03-2018 CXR48_RS00575 34fd7f11144938d23daea078551e68fe 363 ProSitePatterns PS00112 Phosphagen kinase active site signature. 167 173 - T 29-03-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 CXR48_RS00575 34fd7f11144938d23daea078551e68fe 363 Gene3D G3DSA:3.30.590.10 4 255 2.8E-86 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CXR48_RS00575 34fd7f11144938d23daea078551e68fe 363 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 54 253 9.0E-73 T 29-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 CXR48_RS10055 c4d841a7a1070ca7cedfcdd29e68e80b 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 2.0E-66 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CXR48_RS10055 c4d841a7a1070ca7cedfcdd29e68e80b 144 Pfam PF06491 Disulphide isomerase 8 144 2.9E-63 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CXR48_RS10880 dab85e1754d8f025588e6461323f4eb8 218 Pfam PF13367 Protease prsW family 28 198 1.2E-33 T 29-03-2018 IPR026898 Protease PrsW GO:0008233 CXR48_RS10880 dab85e1754d8f025588e6461323f4eb8 218 PIRSF PIRSF016933 1 218 6.8E-88 T 29-03-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 CXR48_RS04025 da432deff43d0bdb26d43044e925d5be 285 ProSitePatterns PS00934 Glyoxalase I signature 1. 172 193 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CXR48_RS04025 da432deff43d0bdb26d43044e925d5be 285 SUPERFAMILY SSF54593 170 275 1.51E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS04025 da432deff43d0bdb26d43044e925d5be 285 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 170 226 7.8E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS04025 da432deff43d0bdb26d43044e925d5be 285 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 123 1.1E-13 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS04025 da432deff43d0bdb26d43044e925d5be 285 Gene3D G3DSA:3.10.180.10 5 166 2.3E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS04025 da432deff43d0bdb26d43044e925d5be 285 Gene3D G3DSA:3.10.180.10 167 284 4.1E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS04025 da432deff43d0bdb26d43044e925d5be 285 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 103 122 - T 29-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CXR48_RS04025 da432deff43d0bdb26d43044e925d5be 285 SUPERFAMILY SSF54593 4 169 1.48E-37 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS00480 38454758fcdb138d8e68f6949b8e2fac 333 PIRSF PIRSF006621 1 330 2.0E-110 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CXR48_RS00480 38454758fcdb138d8e68f6949b8e2fac 333 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 321 2.0E-143 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CXR48_RS00480 38454758fcdb138d8e68f6949b8e2fac 333 Gene3D G3DSA:3.20.20.70 24 242 2.9E-57 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS00480 38454758fcdb138d8e68f6949b8e2fac 333 Pfam PF01207 Dihydrouridine synthase (Dus) 14 321 6.2E-115 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CXR48_RS00480 38454758fcdb138d8e68f6949b8e2fac 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CXR48_RS00480 38454758fcdb138d8e68f6949b8e2fac 333 Gene3D G3DSA:1.10.1200.80 254 332 2.2E-22 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CXR48_RS00480 38454758fcdb138d8e68f6949b8e2fac 333 Gene3D G3DSA:3.20.20.70 1 23 0.12 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS00480 38454758fcdb138d8e68f6949b8e2fac 333 SUPERFAMILY SSF51395 11 321 2.38E-91 T 29-03-2018 CXR48_RS11870 52b970fdbf17edd412b94e0f398c71e5 102 PIRSF PIRSF029928 1 101 1.5E-33 T 29-03-2018 IPR016940 ComG operon protein C GO:0030420 CXR48_RS11870 52b970fdbf17edd412b94e0f398c71e5 102 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 30 5.1E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CXR48_RS11870 52b970fdbf17edd412b94e0f398c71e5 102 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 29 8.9E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CXR48_RS11870 52b970fdbf17edd412b94e0f398c71e5 102 SUPERFAMILY SSF54523 10 85 1.33E-12 T 29-03-2018 CXR48_RS11870 52b970fdbf17edd412b94e0f398c71e5 102 Gene3D G3DSA:3.30.700.10 10 100 3.3E-10 T 29-03-2018 CXR48_RS10350 18dac86afd6d7d279e734d01700ed6fb 70 Pfam PF12728 Helix-turn-helix domain 19 69 1.8E-7 T 29-03-2018 CXR48_RS10350 18dac86afd6d7d279e734d01700ed6fb 70 Gene3D G3DSA:1.10.1660.10 14 70 7.0E-5 T 29-03-2018 CXR48_RS13930 3f641b9b805a29476e18bc98fb928ff0 73 Gene3D G3DSA:1.10.10.10 1 70 9.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13930 3f641b9b805a29476e18bc98fb928ff0 73 SUPERFAMILY SSF46785 11 59 2.61E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13930 3f641b9b805a29476e18bc98fb928ff0 73 SMART SM00420 11 56 0.0044 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS13930 3f641b9b805a29476e18bc98fb928ff0 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 54 5.8E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CXR48_RS08290 d6c92b45b3cecd97b8ef33de0279ffe2 100 Gene3D G3DSA:3.30.1330.30 4 100 6.1E-20 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CXR48_RS08290 d6c92b45b3cecd97b8ef33de0279ffe2 100 SUPERFAMILY SSF55315 6 99 7.97E-26 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CXR48_RS08290 d6c92b45b3cecd97b8ef33de0279ffe2 100 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 56 73 - T 29-03-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0030529|GO:0042254 Reactome: R-HSA-6791226 CXR48_RS08290 d6c92b45b3cecd97b8ef33de0279ffe2 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 8 95 5.8E-20 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CXR48_RS07975 2c6d054e53b265830251ca14ee1e11da 81 SUPERFAMILY SSF54814 22 63 6.54E-6 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CXR48_RS07975 2c6d054e53b265830251ca14ee1e11da 81 Pfam PF13083 KH domain 7 79 4.8E-23 T 29-03-2018 CXR48_RS07975 2c6d054e53b265830251ca14ee1e11da 81 Gene3D G3DSA:3.30.300.20 3 80 1.9E-13 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CXR48_RS07975 2c6d054e53b265830251ca14ee1e11da 81 Hamap MF_00088 UPF0109 protein . 6 80 21.9 T 29-03-2018 IPR020627 Uncharacterised protein family UPF0109 CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 SUPERFAMILY SSF56420 2 152 1.7E-55 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 Gene3D G3DSA:3.90.45.10 1 159 2.7E-56 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 Hamap MF_00163 Peptide deformylase [def]. 2 158 29.707 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 PRINTS PR01576 Peptide deformylase signature 33 62 1.2E-36 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 PRINTS PR01576 Peptide deformylase signature 100 118 1.2E-36 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 PRINTS PR01576 Peptide deformylase signature 119 148 1.2E-36 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 PRINTS PR01576 Peptide deformylase signature 88 99 1.2E-36 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 PIRSF PIRSF004749 1 160 2.3E-49 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 158 3.8E-56 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS07835 a7a3e3e8939d5f637fb854d12cf745fa 160 Pfam PF01327 Polypeptide deformylase 3 147 3.6E-49 T 29-03-2018 IPR023635 Peptide deformylase CXR48_RS15770 97c8dea8e5aea23021b5df0e48017005 335 SUPERFAMILY SSF51679 2 332 8.99E-64 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS15770 97c8dea8e5aea23021b5df0e48017005 335 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 328 5.1E-98 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CXR48_RS15770 97c8dea8e5aea23021b5df0e48017005 335 Gene3D G3DSA:3.20.20.30 2 334 1.7E-57 T 29-03-2018 CXR48_RS15770 97c8dea8e5aea23021b5df0e48017005 335 Pfam PF00296 Luciferase-like monooxygenase 14 296 4.0E-34 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS08530 60edb5c47bb63686722f74eee0483f7f 324 SUPERFAMILY SSF55048 134 197 1.28E-5 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CXR48_RS08530 60edb5c47bb63686722f74eee0483f7f 324 Pfam PF00698 Acyl transferase domain 6 289 2.2E-38 T 29-03-2018 IPR014043 Acyl transferase CXR48_RS08530 60edb5c47bb63686722f74eee0483f7f 324 SUPERFAMILY SSF52151 198 291 1.31E-52 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS08530 60edb5c47bb63686722f74eee0483f7f 324 SUPERFAMILY SSF52151 5 135 1.31E-52 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS08530 60edb5c47bb63686722f74eee0483f7f 324 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8 306 1.2E-41 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CXR48_RS08530 60edb5c47bb63686722f74eee0483f7f 324 Gene3D G3DSA:3.40.366.10 1 155 1.8E-38 T 29-03-2018 CXR48_RS08530 60edb5c47bb63686722f74eee0483f7f 324 Gene3D G3DSA:3.40.366.10 159 298 3.5E-18 T 29-03-2018 CXR48_RS06045 c0c8922f7f6e8deb865d7090aa051b83 253 Pfam PF03649 Uncharacterised protein family (UPF0014) 5 240 7.8E-75 T 29-03-2018 IPR005226 UPF0014 family CXR48_RS06045 c0c8922f7f6e8deb865d7090aa051b83 253 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 2 246 7.6E-98 T 29-03-2018 IPR005226 UPF0014 family CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 SUPERFAMILY SSF49503 127 280 9.18E-38 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 47 106 1.3E-6 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 Gene3D G3DSA:2.60.40.420 118 274 1.1E-38 T 29-03-2018 IPR008972 Cupredoxin CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 Gene3D G3DSA:1.10.287.90 27 110 5.5E-20 T 29-03-2018 CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 SUPERFAMILY SSF81464 14 113 3.76E-18 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 174 228 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 Pfam PF00034 Cytochrome c 259 352 1.5E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 Gene3D G3DSA:1.10.760.10 275 352 1.6E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 31 244 5.5E-50 T 29-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 154 233 2.3E-10 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS07420 aaf4ebbba393f9f2bb0e99b26e9973ea 356 SUPERFAMILY SSF46626 257 353 2.36E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS18220 b89259b5e7bb80530d62e95651df6507 311 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 27 301 1.5E-33 T 29-03-2018 CXR48_RS18220 b89259b5e7bb80530d62e95651df6507 311 Pfam PF01040 UbiA prenyltransferase family 35 264 4.9E-36 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CXR48_RS18220 b89259b5e7bb80530d62e95651df6507 311 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 18 305 18.913 T 29-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CXR48_RS18220 b89259b5e7bb80530d62e95651df6507 311 PIRSF PIRSF005355 10 310 1.8E-94 T 29-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 8.6E-59 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 SUPERFAMILY SSF46785 5 78 6.8E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 9.0E-29 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 Gene3D G3DSA:3.30.1360.40 74 146 4.8E-31 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 Pfam PF02863 Arginine repressor, C-terminal domain 81 145 4.4E-28 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 SUPERFAMILY SSF55252 80 148 1.57E-22 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 3.9E-29 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 3.9E-29 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 3.9E-29 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 3.9E-29 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 Gene3D G3DSA:1.10.10.10 3 66 9.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 1.2E-30 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CXR48_RS11645 174c4124b561c2eedba20e1bf0de9870 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 72.55 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CXR48_RS00325 72b2435d4dfa5db001fa70f81f564fc9 202 Gene3D G3DSA:2.40.240.10 1 92 1.4E-25 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CXR48_RS00325 72b2435d4dfa5db001fa70f81f564fc9 202 Pfam PF01386 Ribosomal L25p family 4 90 4.2E-22 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CXR48_RS00325 72b2435d4dfa5db001fa70f81f564fc9 202 Gene3D G3DSA:2.170.120.20 97 184 1.2E-29 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain CXR48_RS00325 72b2435d4dfa5db001fa70f81f564fc9 202 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 2 181 26.483 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CXR48_RS00325 72b2435d4dfa5db001fa70f81f564fc9 202 SUPERFAMILY SSF50715 2 187 8.37E-56 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CXR48_RS00325 72b2435d4dfa5db001fa70f81f564fc9 202 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 91 2.0E-34 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CXR48_RS00325 72b2435d4dfa5db001fa70f81f564fc9 202 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 4 178 6.9E-62 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CXR48_RS00325 72b2435d4dfa5db001fa70f81f564fc9 202 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 181 1.1E-27 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain CXR48_RS12860 c6a6b747d6c8b13b0831d8795d2b506e 192 Gene3D G3DSA:1.10.287.130 5 69 2.7E-14 T 29-03-2018 CXR48_RS12860 c6a6b747d6c8b13b0831d8795d2b506e 192 SMART SM01317 73 187 2.2E-62 T 29-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal CXR48_RS12860 c6a6b747d6c8b13b0831d8795d2b506e 192 Gene3D G3DSA:3.30.565.30 73 187 3.3E-33 T 29-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal CXR48_RS12860 c6a6b747d6c8b13b0831d8795d2b506e 192 SUPERFAMILY SSF55890 16 190 1.31E-60 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CXR48_RS12860 c6a6b747d6c8b13b0831d8795d2b506e 192 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 18 71 4.7E-22 T 29-03-2018 CXR48_RS12860 c6a6b747d6c8b13b0831d8795d2b506e 192 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 74 186 1.0E-33 T 29-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal CXR48_RS07460 e8135ac6fbe4985449ce28785e18c6ec 136 Pfam PF14071 Putative coat protein 12 136 2.2E-44 T 29-03-2018 IPR025953 Putative coat protein YlbD CXR48_RS11215 600e20c6f4f0f29f1a1577329d0bd392 40 Pfam PF13072 Protein of unknown function (DUF3936) 2 37 1.6E-19 T 29-03-2018 IPR025177 Protein of unknown function DUF3936 CXR48_RS00650 858aa431cd2a3983035bb7f7bfae0a25 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00650 858aa431cd2a3983035bb7f7bfae0a25 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 49 8.0E-16 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00650 858aa431cd2a3983035bb7f7bfae0a25 49 SUPERFAMILY SSF57829 1 49 2.62E-16 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CXR48_RS00650 858aa431cd2a3983035bb7f7bfae0a25 49 Pfam PF00471 Ribosomal protein L33 3 49 4.9E-18 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00650 858aa431cd2a3983035bb7f7bfae0a25 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 17.591 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS02185 58a59804d60758b374f500c247816b83 144 Gene3D G3DSA:1.10.10.10 1 52 2.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02185 58a59804d60758b374f500c247816b83 144 Pfam PF01037 Lrp/AsnC ligand binding domain 69 135 4.9E-13 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CXR48_RS02185 58a59804d60758b374f500c247816b83 144 SUPERFAMILY SSF54909 64 137 1.61E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS02185 58a59804d60758b374f500c247816b83 144 SMART SM00344 3 109 2.0E-44 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CXR48_RS02185 58a59804d60758b374f500c247816b83 144 Gene3D G3DSA:3.30.70.920 53 143 2.0E-19 T 29-03-2018 CXR48_RS02185 58a59804d60758b374f500c247816b83 144 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 3.0E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CXR48_RS02185 58a59804d60758b374f500c247816b83 144 SUPERFAMILY SSF46785 2 62 4.12E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02185 58a59804d60758b374f500c247816b83 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.1E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CXR48_RS02185 58a59804d60758b374f500c247816b83 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.1E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CXR48_RS02185 58a59804d60758b374f500c247816b83 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.1E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CXR48_RS07130 d2e48153a671c0c4f0f256807a91eb99 302 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 150 1.8E-37 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CXR48_RS07130 d2e48153a671c0c4f0f256807a91eb99 302 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 301 1.4E-76 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CXR48_RS07130 d2e48153a671c0c4f0f256807a91eb99 302 Gene3D G3DSA:3.40.50.720 1 175 1.4E-31 T 29-03-2018 CXR48_RS07130 d2e48153a671c0c4f0f256807a91eb99 302 SUPERFAMILY SSF48179 176 300 9.52E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS07130 d2e48153a671c0c4f0f256807a91eb99 302 SUPERFAMILY SSF51735 1 192 1.1E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07130 d2e48153a671c0c4f0f256807a91eb99 302 Gene3D G3DSA:1.10.1040.10 176 302 7.2E-26 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS07130 d2e48153a671c0c4f0f256807a91eb99 302 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 176 299 2.8E-24 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CXR48_RS10285 688d01692314d2a45477b7afdb9f6d67 105 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 5 95 1.0E-17 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CXR48_RS10285 688d01692314d2a45477b7afdb9f6d67 105 Pfam PF05521 Phage head-tail joining protein 6 100 2.4E-24 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CXR48_RS17620 93c24f1c501d40a348701cca7ce8fb63 185 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 14 165 1.9E-64 T 29-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 CXR48_RS17620 93c24f1c501d40a348701cca7ce8fb63 185 Pfam PF02613 Nitrate reductase delta subunit 43 158 2.5E-6 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CXR48_RS17620 93c24f1c501d40a348701cca7ce8fb63 185 Gene3D G3DSA:1.10.3480.10 1 176 4.0E-28 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CXR48_RS17620 93c24f1c501d40a348701cca7ce8fb63 185 SUPERFAMILY SSF89155 6 170 1.44E-29 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CXR48_RS14800 6a2c0e18b8e19d359ba9aa3bf3f2222c 82 ProDom PD060056 YUEH 1 82 3.0E-27 T 29-03-2018 IPR020260 Uncharacterised protein family YueH CXR48_RS14800 6a2c0e18b8e19d359ba9aa3bf3f2222c 82 Pfam PF14166 YueH-like protein 2 81 2.6E-29 T 29-03-2018 IPR020260 Uncharacterised protein family YueH CXR48_RS16265 7bb80ebecc8a6d665d985e858eb918d7 114 Gene3D G3DSA:3.10.450.130 34 113 3.0E-13 T 29-03-2018 CXR48_RS16265 7bb80ebecc8a6d665d985e858eb918d7 114 Pfam PF07252 Protein of unknown function (DUF1433) 36 83 4.3E-9 T 29-03-2018 IPR009881 Protein of unknown function DUF1433 CXR48_RS10145 b2348701f3d1ccb46837b31f566b752a 1193 SUPERFAMILY SSF52540 751 885 4.28E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10145 b2348701f3d1ccb46837b31f566b752a 1193 SUPERFAMILY SSF52540 598 705 4.28E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10145 b2348701f3d1ccb46837b31f566b752a 1193 Gene3D G3DSA:3.40.50.300 591 986 8.1E-42 T 29-03-2018 CXR48_RS10145 b2348701f3d1ccb46837b31f566b752a 1193 Gene3D G3DSA:3.40.50.300 17 582 3.3E-28 T 29-03-2018 CXR48_RS10145 b2348701f3d1ccb46837b31f566b752a 1193 SUPERFAMILY SSF52540 30 268 2.62E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10145 b2348701f3d1ccb46837b31f566b752a 1193 Pfam PF00350 Dynamin family 48 202 6.4E-26 T 29-03-2018 IPR022812 Dynamin superfamily CXR48_RS10145 b2348701f3d1ccb46837b31f566b752a 1193 Pfam PF00350 Dynamin family 614 838 1.3E-38 T 29-03-2018 IPR022812 Dynamin superfamily CXR48_RS04740 c5a330f8fe7bc53df36e77454f1738a7 199 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 19 141 1.0E-37 T 29-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 CXR48_RS04740 c5a330f8fe7bc53df36e77454f1738a7 199 SMART SM00563 33 144 4.2E-29 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CXR48_RS04740 c5a330f8fe7bc53df36e77454f1738a7 199 SUPERFAMILY SSF69593 15 193 2.35E-38 T 29-03-2018 CXR48_RS04740 c5a330f8fe7bc53df36e77454f1738a7 199 Pfam PF01553 Acyltransferase 19 142 4.8E-24 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CXR48_RS04740 c5a330f8fe7bc53df36e77454f1738a7 199 Gene3D G3DSA:3.40.1130.10 1 199 1.9E-36 T 29-03-2018 CXR48_RS17810 07a352b60d884782872e715ecf1e0347 323 Gene3D G3DSA:3.40.50.10750 142 295 9.6E-66 T 29-03-2018 CXR48_RS17810 07a352b60d884782872e715ecf1e0347 323 PIRSF PIRSF000428 1 323 4.4E-112 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CXR48_RS17810 07a352b60d884782872e715ecf1e0347 323 SUPERFAMILY SSF53659 5 322 9.46E-95 T 29-03-2018 CXR48_RS17810 07a352b60d884782872e715ecf1e0347 323 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 4.4E-134 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CXR48_RS17810 07a352b60d884782872e715ecf1e0347 323 Pfam PF01515 Phosphate acetyl/butaryl transferase 5 319 5.5E-132 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CXR48_RS08850 59827cb4bdd1ebc9527186fd915542e6 276 SUPERFAMILY SSF117892 66 203 1.7E-7 T 29-03-2018 IPR001107 Band 7 domain CXR48_RS08850 59827cb4bdd1ebc9527186fd915542e6 276 Pfam PF01145 SPFH domain / Band 7 family 35 218 2.8E-26 T 29-03-2018 IPR001107 Band 7 domain CXR48_RS04730 e4e17d7f440940f49736174e77b93bf5 358 Pfam PF13800 Sigma factor regulator N-terminal 60 154 1.7E-21 T 29-03-2018 IPR029101 Sigma factor regulator, N-terminal CXR48_RS04730 e4e17d7f440940f49736174e77b93bf5 358 Pfam PF13791 Sigma factor regulator C-terminal 206 352 4.1E-37 T 29-03-2018 IPR025672 Sigma factor regulator C-terminal domain CXR48_RS14680 2cc80fbe6c7111ded91eee03d93e4fbc 235 Gene3D G3DSA:1.10.10.10 156 221 7.8E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14680 2cc80fbe6c7111ded91eee03d93e4fbc 235 SUPERFAMILY SSF46785 173 226 3.58E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14680 2cc80fbe6c7111ded91eee03d93e4fbc 235 Gene3D G3DSA:3.40.50.2300 1 147 3.2E-34 T 29-03-2018 CXR48_RS14680 2cc80fbe6c7111ded91eee03d93e4fbc 235 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS14680 2cc80fbe6c7111ded91eee03d93e4fbc 235 SMART SM00448 2 115 2.5E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS14680 2cc80fbe6c7111ded91eee03d93e4fbc 235 SUPERFAMILY SSF52172 1 136 8.25E-37 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS14680 2cc80fbe6c7111ded91eee03d93e4fbc 235 PIRSF PIRSF006171 1 227 1.5E-84 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CXR48_RS15475 be1779328d642d0ac21ee74af9c7a6b9 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 363 2.0E-95 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CXR48_RS15475 be1779328d642d0ac21ee74af9c7a6b9 366 Pfam PF03845 Spore germination protein 9 329 3.2E-95 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CXR48_RS09500 0db62799f7c1414d946a61f69ceb4666 163 SUPERFAMILY SSF109635 3 85 5.36E-10 T 29-03-2018 CXR48_RS09500 0db62799f7c1414d946a61f69ceb4666 163 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 84 118 2.4E-10 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CXR48_RS09500 0db62799f7c1414d946a61f69ceb4666 163 SUPERFAMILY SSF57716 86 118 9.41E-7 T 29-03-2018 CXR48_RS03580 32fb074da6880b680eb187a47ba4bcfc 312 Pfam PF16363 GDP-mannose 4,6 dehydratase 1 302 1.3E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS03580 32fb074da6880b680eb187a47ba4bcfc 312 Gene3D G3DSA:3.40.50.720 1 176 5.7E-34 T 29-03-2018 CXR48_RS03580 32fb074da6880b680eb187a47ba4bcfc 312 Gene3D G3DSA:3.90.25.10 177 312 8.3E-34 T 29-03-2018 CXR48_RS03580 32fb074da6880b680eb187a47ba4bcfc 312 SUPERFAMILY SSF51735 1 309 1.61E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS17300 7ea0b3cd93b1649ca758f40cf988b1ca 128 Pfam PF17319 Family of unknown function (DUF5362) 12 107 4.3E-12 T 29-03-2018 IPR035287 Protein of unknown function DUF5362 CXR48_RS17300 7ea0b3cd93b1649ca758f40cf988b1ca 128 ProDom PD031895 YWNG MEMBRANE TRANSMEMBRANE YWNC 4 122 2.0E-28 T 29-03-2018 IPR035287 Protein of unknown function DUF5362 CXR48_RS08945 322ba945d0ea62580e57f3b64d175aac 169 SUPERFAMILY SSF52833 10 166 2.07E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS08945 322ba945d0ea62580e57f3b64d175aac 169 Gene3D G3DSA:3.40.30.10 22 168 1.0E-38 T 29-03-2018 CXR48_RS08945 322ba945d0ea62580e57f3b64d175aac 169 Pfam PF00578 AhpC/TSA family 36 151 8.5E-30 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CXR48_RS03375 0695a1ef39b20886980ecd3777ede741 331 Pfam PF01636 Phosphotransferase enzyme family 30 237 9.9E-29 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CXR48_RS03375 0695a1ef39b20886980ecd3777ede741 331 Gene3D G3DSA:3.30.200.20 1 103 1.9E-16 T 29-03-2018 CXR48_RS03375 0695a1ef39b20886980ecd3777ede741 331 SUPERFAMILY SSF56112 13 305 8.8E-55 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS03375 0695a1ef39b20886980ecd3777ede741 331 Gene3D G3DSA:3.90.1200.10 104 320 6.6E-18 T 29-03-2018 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 SUPERFAMILY SSF103473 247 418 3.66E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 SUPERFAMILY SSF103473 7 193 3.66E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 SUPERFAMILY SSF103473 487 516 3.66E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 Gene3D G3DSA:1.20.1250.20 251 530 4.5E-36 T 29-03-2018 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 6.6E-15 T 29-03-2018 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 6.6E-15 T 29-03-2018 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 301 325 6.6E-15 T 29-03-2018 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 6.6E-15 T 29-03-2018 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 6.6E-15 T 29-03-2018 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 435 7.1E-88 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 Pfam PF07690 Major Facilitator Superfamily 17 408 1.9E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS15385 1bb3faf82e57f61fbd9c0aac5c57be48 531 Gene3D G3DSA:1.20.1250.20 8 196 5.1E-33 T 29-03-2018 CXR48_RS13900 a91f2347ee4af548bf5d186bcb58e42f 323 SUPERFAMILY SSF53686 15 320 1.83E-96 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS13900 a91f2347ee4af548bf5d186bcb58e42f 323 TIGRFAM TIGR01139 cysK: cysteine synthase A 21 320 1.2E-132 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CXR48_RS13900 a91f2347ee4af548bf5d186bcb58e42f 323 TIGRFAM TIGR01136 cysKM: cysteine synthase 21 320 1.0E-124 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CXR48_RS13900 a91f2347ee4af548bf5d186bcb58e42f 323 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 22 306 1.7E-68 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS13900 a91f2347ee4af548bf5d186bcb58e42f 323 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 46 64 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CXR48_RS13900 a91f2347ee4af548bf5d186bcb58e42f 323 Gene3D G3DSA:3.40.50.1100 153 322 1.6E-52 T 29-03-2018 CXR48_RS13900 a91f2347ee4af548bf5d186bcb58e42f 323 Gene3D G3DSA:3.40.50.1100 54 152 7.6E-38 T 29-03-2018 CXR48_RS11775 5754348a31eb9fee806704de2524c742 142 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 60 8.0E-27 T 29-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CXR48_RS11775 5754348a31eb9fee806704de2524c742 142 SMART SM00529 24 123 4.1E-46 T 29-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CXR48_RS11775 5754348a31eb9fee806704de2524c742 142 SUPERFAMILY SSF46785 3 62 2.98E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11775 5754348a31eb9fee806704de2524c742 142 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 45.212 T 29-03-2018 IPR022897 Transcription regulator MntR CXR48_RS11775 5754348a31eb9fee806704de2524c742 142 Gene3D G3DSA:1.10.60.10 75 136 1.3E-23 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CXR48_RS11775 5754348a31eb9fee806704de2524c742 142 SUPERFAMILY SSF47979 63 133 3.26E-19 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CXR48_RS11775 5754348a31eb9fee806704de2524c742 142 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 126 1.2E-18 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CXR48_RS11775 5754348a31eb9fee806704de2524c742 142 Gene3D G3DSA:1.10.10.10 1 72 2.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17285 e45309932b8b0282030d7df5b15f1384 149 ProDom PD031895 YWNG MEMBRANE TRANSMEMBRANE YWNC 19 119 1.0E-27 T 29-03-2018 IPR035287 Protein of unknown function DUF5362 CXR48_RS17285 e45309932b8b0282030d7df5b15f1384 149 Pfam PF17319 Family of unknown function (DUF5362) 22 117 6.3E-8 T 29-03-2018 IPR035287 Protein of unknown function DUF5362 CXR48_RS03100 c2bd79cc8aa729c026678528e6688561 592 Pfam PF00271 Helicase conserved C-terminal domain 403 519 2.2E-4 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS03100 c2bd79cc8aa729c026678528e6688561 592 Gene3D G3DSA:3.40.50.300 386 559 1.5E-16 T 29-03-2018 CXR48_RS03100 c2bd79cc8aa729c026678528e6688561 592 SUPERFAMILY SSF52540 107 304 5.08E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03100 c2bd79cc8aa729c026678528e6688561 592 SMART SM00487 116 304 6.6E-10 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS03100 c2bd79cc8aa729c026678528e6688561 592 Pfam PF00176 SNF2 family N-terminal domain 142 361 1.5E-16 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CXR48_RS03100 c2bd79cc8aa729c026678528e6688561 592 Gene3D G3DSA:3.40.50.10810 84 363 1.6E-24 T 29-03-2018 CXR48_RS03100 c2bd79cc8aa729c026678528e6688561 592 SUPERFAMILY SSF52540 315 583 7.5E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07300 0b8146ca67c7c1e96f63c71f9c077e35 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 384 457 5.0E-12 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CXR48_RS07300 0b8146ca67c7c1e96f63c71f9c077e35 490 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CXR48_RS07300 0b8146ca67c7c1e96f63c71f9c077e35 490 SUPERFAMILY SSF55904 341 487 1.83E-40 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CXR48_RS07300 0b8146ca67c7c1e96f63c71f9c077e35 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 368 2.2E-120 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CXR48_RS07300 0b8146ca67c7c1e96f63c71f9c077e35 490 Gene3D G3DSA:3.40.640.10 6 284 1.0E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS07300 0b8146ca67c7c1e96f63c71f9c077e35 490 Gene3D G3DSA:3.90.100.10 372 490 4.7E-36 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CXR48_RS07300 0b8146ca67c7c1e96f63c71f9c077e35 490 SUPERFAMILY SSF53383 6 385 7.61E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 9.2E-45 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 352 39.213 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 SUPERFAMILY SSF52490 13 208 9.03E-72 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 Gene3D G3DSA:3.40.50.1440 10 214 3.8E-47 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.5E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.5E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.5E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.5E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 SMART SM00864 13 205 1.4E-116 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 Pfam PF12327 FtsZ family, C-terminal domain 222 315 3.7E-32 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 SMART SM00865 207 324 5.4E-54 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 340 1.8E-141 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 SUPERFAMILY SSF55307 204 315 6.41E-43 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 Gene3D G3DSA:3.30.1330.20 215 324 1.5E-45 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CXR48_RS07610 536d06ebeff6215568e9cd1b429d9c6f 382 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 Gene3D G3DSA:1.10.3860.10 2 405 2.5E-123 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 142 164 7.0E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 216 235 7.0E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 72 97 7.0E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 289 315 7.0E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 189 208 7.0E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 7.0E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 324 343 7.0E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 34 49 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 292 315 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 SUPERFAMILY SSF118215 7 399 6.54E-123 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS02330 632f35b6644d6a2922f1cccf89da4713 418 Pfam PF00375 Sodium:dicarboxylate symporter family 7 397 1.3E-117 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CXR48_RS03680 f453ee39b3799e4b912b21bf5fdc02d9 478 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 32 472 4.4E-135 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CXR48_RS03680 f453ee39b3799e4b912b21bf5fdc02d9 478 PIRSF PIRSF002457 1 478 1.9E-171 T 29-03-2018 IPR030676 Citrate carrier CitT-related CXR48_RS03680 f453ee39b3799e4b912b21bf5fdc02d9 478 Pfam PF00939 Sodium:sulfate symporter transmembrane region 14 478 1.1E-181 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CXR48_RS05740 1ae252f5ac48202136d240716a32e5c6 67 Pfam PF02597 ThiS family 6 67 8.2E-13 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CXR48_RS05740 1ae252f5ac48202136d240716a32e5c6 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 67 1.5E-23 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis CXR48_RS05740 1ae252f5ac48202136d240716a32e5c6 67 Gene3D G3DSA:3.10.20.30 1 67 6.5E-18 T 29-03-2018 IPR012675 Beta-grasp domain CXR48_RS05740 1ae252f5ac48202136d240716a32e5c6 67 SUPERFAMILY SSF54285 3 66 4.09E-18 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CXR48_RS06735 d2f5e59935d3b3c3e0702f23af61363b 404 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 2 399 60.285 T 29-03-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 CXR48_RS06735 d2f5e59935d3b3c3e0702f23af61363b 404 Gene3D G3DSA:3.20.20.110 114 403 1.4E-85 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CXR48_RS06735 d2f5e59935d3b3c3e0702f23af61363b 404 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 3 92 5.2E-9 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CXR48_RS06735 d2f5e59935d3b3c3e0702f23af61363b 404 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 399 1.4E-227 T 29-03-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 CXR48_RS06735 d2f5e59935d3b3c3e0702f23af61363b 404 SUPERFAMILY SSF51649 114 401 1.14E-82 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CXR48_RS06735 d2f5e59935d3b3c3e0702f23af61363b 404 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 321 398 5.3E-16 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CXR48_RS06735 d2f5e59935d3b3c3e0702f23af61363b 404 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 119 288 2.9E-22 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CXR48_RS06735 d2f5e59935d3b3c3e0702f23af61363b 404 SUPERFAMILY SSF54966 1 111 5.37E-31 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CXR48_RS06735 d2f5e59935d3b3c3e0702f23af61363b 404 Gene3D G3DSA:3.30.70.150 1 112 1.3E-28 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CXR48_RS01995 11a7d710828039bc7c5c9875da56df19 291 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 2.2E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS01995 11a7d710828039bc7c5c9875da56df19 291 SUPERFAMILY SSF46689 3 64 3.69E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS01995 11a7d710828039bc7c5c9875da56df19 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS01995 11a7d710828039bc7c5c9875da56df19 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS01995 11a7d710828039bc7c5c9875da56df19 291 Gene3D G3DSA:1.10.357.10 2 281 6.7E-25 T 29-03-2018 CXR48_RS05060 bf9ed79306a8e521a3189536b4f9bca7 477 Gene3D G3DSA:3.50.50.60 2 93 2.0E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS05060 bf9ed79306a8e521a3189536b4f9bca7 477 Gene3D G3DSA:1.10.3110.10 114 211 4.3E-32 T 29-03-2018 CXR48_RS05060 bf9ed79306a8e521a3189536b4f9bca7 477 Pfam PF01593 Flavin containing amine oxidoreductase 15 461 2.6E-70 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CXR48_RS05060 bf9ed79306a8e521a3189536b4f9bca7 477 SUPERFAMILY SSF54373 308 415 1.01E-33 T 29-03-2018 CXR48_RS05060 bf9ed79306a8e521a3189536b4f9bca7 477 Gene3D G3DSA:3.90.660.20 218 415 4.4E-43 T 29-03-2018 CXR48_RS05060 bf9ed79306a8e521a3189536b4f9bca7 477 SUPERFAMILY SSF51905 6 323 1.01E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS05060 bf9ed79306a8e521a3189536b4f9bca7 477 SUPERFAMILY SSF51905 433 461 1.01E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS05060 bf9ed79306a8e521a3189536b4f9bca7 477 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 5 469 2.3E-174 T 29-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CXR48_RS04900 935c82975e75ddba14bdeebca23d2188 165 PIRSF PIRSF005028 1 163 5.8E-59 T 29-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT CXR48_RS04900 935c82975e75ddba14bdeebca23d2188 165 Pfam PF02080 TrkA-C domain 90 156 7.6E-14 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS04900 935c82975e75ddba14bdeebca23d2188 165 Gene3D G3DSA:3.30.70.1450 73 163 3.0E-17 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS04900 935c82975e75ddba14bdeebca23d2188 165 SUPERFAMILY SSF116726 79 158 2.09E-17 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS00140 dc7ac0ab177d4f7ae0ab3eab6a0c2efa 107 Pfam PF02575 YbaB/EbfC DNA-binding family 12 102 4.0E-35 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CXR48_RS00140 dc7ac0ab177d4f7ae0ab3eab6a0c2efa 107 Gene3D G3DSA:3.30.1310.10 1 107 2.7E-38 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CXR48_RS00140 dc7ac0ab177d4f7ae0ab3eab6a0c2efa 107 PIRSF PIRSF004555 4 107 8.7E-41 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CXR48_RS00140 dc7ac0ab177d4f7ae0ab3eab6a0c2efa 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 106 5.1E-35 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CXR48_RS00140 dc7ac0ab177d4f7ae0ab3eab6a0c2efa 107 SUPERFAMILY SSF82607 12 106 2.09E-34 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CXR48_RS00140 dc7ac0ab177d4f7ae0ab3eab6a0c2efa 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 6 100 23.52 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CXR48_RS13610 f306a62acfd434bb6cdf66bd452329bf 163 Pfam PF06271 RDD family 25 152 3.6E-22 T 29-03-2018 IPR010432 RDD CXR48_RS17945 9bffe438ef5aa697587e0dfd6a79c6ce 181 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 92 173 1.8E-48 T 29-03-2018 IPR014099 Spore coat protein GerQ CXR48_RS17945 9bffe438ef5aa697587e0dfd6a79c6ce 181 Pfam PF09671 Spore coat protein (Spore_GerQ) 94 169 9.7E-42 T 29-03-2018 IPR014099 Spore coat protein GerQ CXR48_RS17945 9bffe438ef5aa697587e0dfd6a79c6ce 181 PIRSF PIRSF038931 1 72 980.0 T 29-03-2018 IPR014099 Spore coat protein GerQ CXR48_RS17945 9bffe438ef5aa697587e0dfd6a79c6ce 181 PIRSF PIRSF038931 29 181 4.7E-52 T 29-03-2018 IPR014099 Spore coat protein GerQ CXR48_RS01565 56bdf0ef3e7770a343ce18f53d3580b0 540 Pfam PF14266 Putative component of 'biosynthetic module' 40 525 9.2E-156 T 29-03-2018 IPR025647 Putative component of 'biosynthetic module' CXR48_RS07885 f918e7f47437ba6d4877f54d7c18753f 62 Pfam PF00830 Ribosomal L28 family 3 58 7.4E-21 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07885 f918e7f47437ba6d4877f54d7c18753f 62 Gene3D G3DSA:2.30.170.40 2 62 3.1E-19 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07885 f918e7f47437ba6d4877f54d7c18753f 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 3.0E-23 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS07885 f918e7f47437ba6d4877f54d7c18753f 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 19.847 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS07885 f918e7f47437ba6d4877f54d7c18753f 62 SUPERFAMILY SSF143800 1 60 3.53E-24 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS10625 3a06687a388ebdd09a4f217c96eb29ca 278 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 263 42.896 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CXR48_RS10625 3a06687a388ebdd09a4f217c96eb29ca 278 SUPERFAMILY SSF51621 3 263 3.04E-106 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CXR48_RS10625 3a06687a388ebdd09a4f217c96eb29ca 278 Gene3D G3DSA:3.20.20.60 1 263 5.9E-84 T 29-03-2018 CXR48_RS10625 3a06687a388ebdd09a4f217c96eb29ca 278 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 264 8.5E-130 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CXR48_RS10625 3a06687a388ebdd09a4f217c96eb29ca 278 PIRSF PIRSF000388 1 266 2.1E-110 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CXR48_RS10625 3a06687a388ebdd09a4f217c96eb29ca 278 Pfam PF02548 Ketopantoate hydroxymethyltransferase 5 259 3.6E-111 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CXR48_RS00445 2f0230f490002f3e303a09cfffa95295 473 Pfam PF00425 chorismate binding enzyme 200 453 5.3E-98 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CXR48_RS00445 2f0230f490002f3e303a09cfffa95295 473 Gene3D G3DSA:3.60.120.10 4 465 6.4E-155 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CXR48_RS00445 2f0230f490002f3e303a09cfffa95295 473 PRINTS PR00095 Anthranilate synthase component I signature 301 314 1.7E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS00445 2f0230f490002f3e303a09cfffa95295 473 PRINTS PR00095 Anthranilate synthase component I signature 410 424 1.7E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS00445 2f0230f490002f3e303a09cfffa95295 473 PRINTS PR00095 Anthranilate synthase component I signature 395 409 1.7E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS00445 2f0230f490002f3e303a09cfffa95295 473 PRINTS PR00095 Anthranilate synthase component I signature 315 328 1.7E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS00445 2f0230f490002f3e303a09cfffa95295 473 Pfam PF04715 Anthranilate synthase component I, N terminal region 18 150 5.3E-28 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS00445 2f0230f490002f3e303a09cfffa95295 473 TIGRFAM TIGR01824 PabB-clade2: aminodeoxychorismate synthase, component I 100 456 1.1E-124 T 29-03-2018 IPR010118 Para-aminobenzoate synthase/anthranilate synthase, component I CXR48_RS00445 2f0230f490002f3e303a09cfffa95295 473 SUPERFAMILY SSF56322 16 463 8.77E-146 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CXR48_RS07295 013e6b47ea6b38ae680c8ce3fd81f7bf 39 Pfam PF13790 SR1 protein 1 38 9.5E-21 T 29-03-2018 IPR025236 SR1 protein CXR48_RS00120 b91c5203a52b110bcd4ad5ec56501a30 183 Pfam PF00857 Isochorismatase family 7 176 2.2E-33 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS00120 b91c5203a52b110bcd4ad5ec56501a30 183 Gene3D G3DSA:3.40.50.850 1 183 2.5E-38 T 29-03-2018 CXR48_RS00120 b91c5203a52b110bcd4ad5ec56501a30 183 SUPERFAMILY SSF52499 3 181 2.88E-46 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 SMART SM00448 1 112 2.6E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 SUPERFAMILY SSF52172 2 117 5.69E-29 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 226 3.9E-7 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 SUPERFAMILY SSF46894 154 228 8.5E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 SUPERFAMILY SSF48452 287 354 8.73E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 Gene3D G3DSA:1.10.10.10 127 231 5.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 Gene3D G3DSA:1.25.40.10 281 356 2.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 SMART SM00862 154 228 0.0036 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 Gene3D G3DSA:3.40.50.2300 1 126 7.0E-28 T 29-03-2018 CXR48_RS03700 0bc2301054244b09e54d5db14aa37fff 358 Pfam PF00072 Response regulator receiver domain 4 112 2.4E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS03505 f8bd646d6390be0c5a5a3cd9712d5d35 177 Pfam PF00583 Acetyltransferase (GNAT) family 50 159 4.5E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS03505 f8bd646d6390be0c5a5a3cd9712d5d35 177 SUPERFAMILY SSF55729 15 166 1.5E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS03505 f8bd646d6390be0c5a5a3cd9712d5d35 177 Gene3D G3DSA:3.40.630.30 5 177 9.6E-25 T 29-03-2018 CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 Gene3D G3DSA:1.20.5.420 3 31 1.6E-19 T 29-03-2018 CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 4.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 4.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 4.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 4.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 Pfam PF01047 MarR family 36 92 4.1E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 SMART SM00347 28 128 1.4E-30 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 Gene3D G3DSA:1.10.287.100 107 145 1.1E-11 T 29-03-2018 CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 Gene3D G3DSA:1.10.10.10 32 106 1.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15380 ae55bfea8da14697209958ae1f4e158b 153 SUPERFAMILY SSF46785 14 142 3.9E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02175 d3c59f9fed76291adfb59fd590ff5cd9 269 Pfam PF10997 Alternate to MurJ 15 266 9.6E-98 T 29-03-2018 IPR021260 Lipid II flippase Amj CXR48_RS02175 d3c59f9fed76291adfb59fd590ff5cd9 269 Hamap MF_02077 Lipid II flippase Amj [amj]. 5 267 26.916 T 29-03-2018 IPR021260 Lipid II flippase Amj CXR48_RS07985 cccd6c1700d0416882b0fe282cf7ef83 174 Pfam PF01782 RimM N-terminal domain 8 92 4.6E-21 T 29-03-2018 IPR002676 RimM protein GO:0006364 CXR48_RS07985 cccd6c1700d0416882b0fe282cf7ef83 174 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 171 6.5E-52 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CXR48_RS07985 cccd6c1700d0416882b0fe282cf7ef83 174 Gene3D G3DSA:2.40.30.60 4 94 6.8E-23 T 29-03-2018 IPR002676 RimM protein GO:0006364 CXR48_RS07985 cccd6c1700d0416882b0fe282cf7ef83 174 Gene3D G3DSA:2.30.30.240 97 166 5.5E-23 T 29-03-2018 CXR48_RS07985 cccd6c1700d0416882b0fe282cf7ef83 174 Pfam PF05239 PRC-barrel domain 98 171 1.8E-15 T 29-03-2018 IPR027275 PRC-barrel domain CXR48_RS07985 cccd6c1700d0416882b0fe282cf7ef83 174 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 171 23.464 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CXR48_RS07985 cccd6c1700d0416882b0fe282cf7ef83 174 SUPERFAMILY SSF50447 5 93 1.94E-20 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CXR48_RS07985 cccd6c1700d0416882b0fe282cf7ef83 174 SUPERFAMILY SSF50346 101 171 6.28E-20 T 29-03-2018 IPR011033 PRC-barrel-like CXR48_RS15815 5335e9c844fd7e80184cd8eb701f8314 101 SUPERFAMILY SSF52038 1 89 1.12E-27 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CXR48_RS15815 5335e9c844fd7e80184cd8eb701f8314 101 Gene3D G3DSA:3.30.370.10 1 90 2.2E-28 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CXR48_RS15815 5335e9c844fd7e80184cd8eb701f8314 101 Pfam PF01337 Barstar (barnase inhibitor) 6 83 3.3E-23 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 Gene3D G3DSA:3.40.47.10 1 140 4.4E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 Gene3D G3DSA:3.40.47.10 142 262 6.9E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 Pfam PF02803 Thiolase, C-terminal domain 269 389 3.7E-48 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 Gene3D G3DSA:3.40.47.10 263 388 2.7E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 PIRSF PIRSF000429 1 391 8.4E-132 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 Pfam PF00108 Thiolase, N-terminal domain 5 260 1.1E-78 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 SUPERFAMILY SSF53901 1 264 1.04E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 SUPERFAMILY SSF53901 270 390 1.75E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS15345 af8611b99e0f638406fd3b917ff7e61d 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 3.2E-140 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CXR48_RS13305 07f608614d524abd9223a690f030a782 497 PIRSF PIRSF001478 1 496 1.9E-251 T 29-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CXR48_RS13305 07f608614d524abd9223a690f030a782 497 SUPERFAMILY SSF50443 326 494 1.2E-71 T 29-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal CXR48_RS13305 07f608614d524abd9223a690f030a782 497 SUPERFAMILY SSF53743 3 324 4.71E-119 T 29-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 CXR48_RS13305 07f608614d524abd9223a690f030a782 497 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 5 302 7.0E-156 T 29-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CXR48_RS13305 07f608614d524abd9223a690f030a782 497 Hamap MF_00519 L-arabinose isomerase [araA]. 1 473 63.139 T 29-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CXR48_RS13305 07f608614d524abd9223a690f030a782 497 Pfam PF11762 L-arabinose isomerase C-terminal domain 359 472 1.5E-48 T 29-03-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 CXR48_RS13305 07f608614d524abd9223a690f030a782 497 Pfam PF02610 L-arabinose isomerase 5 356 9.7E-175 T 29-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CXR48_RS11240 27c22d87461098c3a5a80e432b5e088d 120 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 104 3.7E-24 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CXR48_RS11240 27c22d87461098c3a5a80e432b5e088d 120 SUPERFAMILY SSF89360 1 105 1.83E-24 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CXR48_RS11240 27c22d87461098c3a5a80e432b5e088d 120 Gene3D G3DSA:2.60.300.12 1 106 3.5E-30 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CXR48_RS12360 8131c5d7f0c675638f900d106f3a5fe7 244 Pfam PF01522 Polysaccharide deacetylase 43 162 4.1E-31 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CXR48_RS12360 8131c5d7f0c675638f900d106f3a5fe7 244 SUPERFAMILY SSF88713 31 235 4.94E-62 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CXR48_RS12360 8131c5d7f0c675638f900d106f3a5fe7 244 Gene3D G3DSA:3.20.20.370 17 242 4.5E-59 T 29-03-2018 CXR48_RS09900 80f91c289e9ae476dee5fe5f958856c3 124 Pfam PF14037 YoqO-like protein 5 115 2.5E-20 T 29-03-2018 IPR025621 YoqO-like protein CXR48_RS10050 7e6ed9274a7d9140c7e9fa1d38b7af71 256 Pfam PF04445 Putative SAM-dependent methyltransferase 44 187 3.5E-15 T 29-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 CXR48_RS10050 7e6ed9274a7d9140c7e9fa1d38b7af71 256 SUPERFAMILY SSF53335 1 253 1.25E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS10050 7e6ed9274a7d9140c7e9fa1d38b7af71 256 Gene3D G3DSA:3.40.50.150 66 253 9.0E-22 T 29-03-2018 CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 373 381 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 SUPERFAMILY SSF51445 2 473 7.34E-163 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 Gene3D G3DSA:3.20.20.80 1 479 2.8E-151 T 29-03-2018 CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 Pfam PF00232 Glycosyl hydrolase family 1 3 476 5.5E-134 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 4.5E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 4.5E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 381 4.5E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 405 4.5E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS09700 2793fd424bcd59155115c80d5a48b79d 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 4.5E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS03925 a647aed6fa81514a733c2a08d39f3ef6 286 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 158 4.5E-37 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CXR48_RS03925 a647aed6fa81514a733c2a08d39f3ef6 286 SUPERFAMILY SSF51735 1 162 5.44E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS03925 a647aed6fa81514a733c2a08d39f3ef6 286 SUPERFAMILY SSF48179 167 285 4.65E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS03925 a647aed6fa81514a733c2a08d39f3ef6 286 Gene3D G3DSA:3.40.50.720 1 161 7.0E-28 T 29-03-2018 CXR48_RS03925 a647aed6fa81514a733c2a08d39f3ef6 286 Gene3D G3DSA:1.10.1040.10 162 286 1.4E-24 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS03925 a647aed6fa81514a733c2a08d39f3ef6 286 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 284 1.9E-17 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CXR48_RS03925 a647aed6fa81514a733c2a08d39f3ef6 286 PIRSF PIRSF000103 1 286 3.5E-85 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CXR48_RS02260 7fd20b88270102432d5750338de48cab 425 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 29 392 1.9E-131 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CXR48_RS02260 7fd20b88270102432d5750338de48cab 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 137 156 1.8E-31 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CXR48_RS02260 7fd20b88270102432d5750338de48cab 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 212 235 1.8E-31 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CXR48_RS02260 7fd20b88270102432d5750338de48cab 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 314 333 1.8E-31 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CXR48_RS02260 7fd20b88270102432d5750338de48cab 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 162 183 1.8E-31 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CXR48_RS02260 7fd20b88270102432d5750338de48cab 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 109 135 1.8E-31 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CXR48_RS02260 7fd20b88270102432d5750338de48cab 425 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 13 424 38.046 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CXR48_RS02260 7fd20b88270102432d5750338de48cab 425 Pfam PF01566 Natural resistance-associated macrophage protein 50 399 3.9E-121 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CXR48_RS03230 8a081745ef6fc875e383cabe9625e9ac 177 SUPERFAMILY SSF88946 3 87 1.44E-20 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS03230 8a081745ef6fc875e383cabe9625e9ac 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 165 3.3E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS03230 8a081745ef6fc875e383cabe9625e9ac 177 Gene3D G3DSA:1.10.10.10 100 177 1.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03230 8a081745ef6fc875e383cabe9625e9ac 177 Gene3D G3DSA:1.10.1740.10 1 99 1.3E-17 T 29-03-2018 CXR48_RS03230 8a081745ef6fc875e383cabe9625e9ac 177 Pfam PF08281 Sigma-70, region 4 110 161 4.9E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS03230 8a081745ef6fc875e383cabe9625e9ac 177 Pfam PF04542 Sigma-70 region 2 21 81 9.7E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS03230 8a081745ef6fc875e383cabe9625e9ac 177 SUPERFAMILY SSF88659 108 167 1.01E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 Pfam PF13604 AAA domain 341 549 2.5E-50 T 29-03-2018 CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 SUPERFAMILY SSF52540 335 729 1.23E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 Gene3D G3DSA:3.40.50.300 523 737 2.6E-29 T 29-03-2018 CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 Gene3D G3DSA:1.10.150.20 102 156 1.2E-5 T 29-03-2018 CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 Gene3D G3DSA:1.10.150.20 164 216 0.05 T 29-03-2018 CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 SMART SM00382 354 508 7.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 12 750 9.6E-257 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 Gene3D G3DSA:3.40.50.300 296 522 5.3E-35 T 29-03-2018 CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 9 753 29.883 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 Pfam PF14490 Helix-hairpin-helix containing domain 154 244 8.2E-31 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CXR48_RS12660 d8269850992231a49d236f74b33e818d 792 Pfam PF13538 UvrD-like helicase C-terminal domain 676 724 4.5E-18 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain CXR48_RS10875 ce044131109a2a4e821f816b45dc23e2 289 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 29 288 1.0E-95 T 29-03-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 CXR48_RS10875 ce044131109a2a4e821f816b45dc23e2 289 Pfam PF01471 Putative peptidoglycan binding domain 40 97 2.1E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS10875 ce044131109a2a4e821f816b45dc23e2 289 Gene3D G3DSA:1.10.101.10 30 100 5.3E-20 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS10875 ce044131109a2a4e821f816b45dc23e2 289 Pfam PF07486 Cell Wall Hydrolase 190 288 3.1E-26 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CXR48_RS10875 ce044131109a2a4e821f816b45dc23e2 289 SUPERFAMILY SSF47090 31 97 7.26E-19 T 29-03-2018 IPR002477 Peptidoglycan binding-like CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 SUPERFAMILY SSF53850 88 290 4.24E-27 T 29-03-2018 CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 Pfam PF03466 LysR substrate binding domain 87 287 2.2E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 Gene3D G3DSA:1.10.10.10 1 89 1.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 Gene3D G3DSA:3.40.190.10 166 257 1.9E-8 T 29-03-2018 CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 Gene3D G3DSA:3.40.190.10 91 165 5.1E-13 T 29-03-2018 CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 SUPERFAMILY SSF46785 1 87 1.13E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS06995 25d34f813ecb33c6606bac6ea356e4fc 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CXR48_RS05190 10cb13a32173c2d464c8560092a083d6 122 SUPERFAMILY SSF159888 1 122 2.75E-38 T 29-03-2018 CXR48_RS05190 10cb13a32173c2d464c8560092a083d6 122 Pfam PF08818 Domain of unknown function (DU1801) 19 110 1.9E-12 T 29-03-2018 IPR014922 Domain of unknown function DUF1801 CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 Pfam PF05922 Peptidase inhibitor I9 54 139 2.0E-10 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 Gene3D G3DSA:2.60.40.10 609 695 8.4E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 SUPERFAMILY SSF52025 374 468 3.53E-19 T 29-03-2018 CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 Pfam PF02225 PA domain 380 458 7.8E-15 T 29-03-2018 IPR003137 PA domain CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 Gene3D G3DSA:3.40.50.200 140 598 4.6E-93 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 Gene3D G3DSA:3.30.70.80 47 139 3.0E-11 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 Pfam PF13860 FlgD Ig-like domain 714 788 1.6E-7 T 29-03-2018 IPR025965 FlgD Ig-like domain CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 230 240 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 PRINTS PR00723 Subtilisin serine protease family (S8) signature 528 544 7.2E-21 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 PRINTS PR00723 Subtilisin serine protease family (S8) signature 226 239 7.2E-21 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 PRINTS PR00723 Subtilisin serine protease family (S8) signature 177 196 7.2E-21 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 529 539 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 Pfam PF00082 Subtilase family 177 583 2.6E-82 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 182 193 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 SUPERFAMILY SSF52743 484 593 1.7E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS18020 5b0c29149d052de9d2a8e71e3076bd87 803 SUPERFAMILY SSF52743 158 349 1.7E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CXR48_RS08855 93cf6a4aad3ed325767b7342cdf4183b 149 Pfam PF10710 Protein of unknown function (DUF2512) 1 138 3.6E-40 T 29-03-2018 IPR019649 Protein of unknown function DUF2512 CXR48_RS10935 e5b5e2ebfbb242a717174d8d09a8a4ae 190 Pfam PF12822 ECF transporter, substrate-specific component 4 172 5.6E-23 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CXR48_RS10935 e5b5e2ebfbb242a717174d8d09a8a4ae 190 PIRSF PIRSF037778 1 186 5.7E-47 T 29-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CXR48_RS05735 629959834cd63f202bb3d218b915a9cd 369 Gene3D G3DSA:3.50.50.60 1 369 3.1E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS05735 629959834cd63f202bb3d218b915a9cd 369 SUPERFAMILY SSF51905 4 219 5.18E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS05735 629959834cd63f202bb3d218b915a9cd 369 SUPERFAMILY SSF51905 306 363 5.18E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS05735 629959834cd63f202bb3d218b915a9cd 369 Pfam PF01266 FAD dependent oxidoreductase 6 344 7.3E-70 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CXR48_RS05735 629959834cd63f202bb3d218b915a9cd 369 SUPERFAMILY SSF54373 220 305 8.5E-20 T 29-03-2018 CXR48_RS05735 629959834cd63f202bb3d218b915a9cd 369 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 8 350 1.7E-110 T 29-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CXR48_RS02000 c528b339ac06f8277609864567ba829a 248 PIRSF PIRSF005426 1 247 4.2E-91 T 29-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 CXR48_RS02000 c528b339ac06f8277609864567ba829a 248 Pfam PF00881 Nitroreductase family 11 165 1.7E-20 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CXR48_RS02000 c528b339ac06f8277609864567ba829a 248 SUPERFAMILY SSF55469 1 246 2.09E-71 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS02000 c528b339ac06f8277609864567ba829a 248 Gene3D G3DSA:3.40.109.10 1 247 2.0E-60 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS18025 5a23769398611202a47309140edc63e9 333 Gene3D G3DSA:3.20.20.30 9 333 9.8E-67 T 29-03-2018 CXR48_RS18025 5a23769398611202a47309140edc63e9 333 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 329 7.3E-120 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CXR48_RS18025 5a23769398611202a47309140edc63e9 333 SUPERFAMILY SSF51679 3 329 1.12E-69 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS18025 5a23769398611202a47309140edc63e9 333 Pfam PF00296 Luciferase-like monooxygenase 18 305 3.1E-37 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS08550 10ba5fa8f311a6b5257a3ff039ea156a 257 Gene3D G3DSA:3.90.226.10 1 257 4.7E-47 T 29-03-2018 CXR48_RS08550 10ba5fa8f311a6b5257a3ff039ea156a 257 SUPERFAMILY SSF52096 2 253 1.76E-47 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS08550 10ba5fa8f311a6b5257a3ff039ea156a 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 253 5.1E-64 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CXR48_RS02290 c67318d79765023fdda539b28d8134eb 268 Pfam PF12787 EcsC protein family 9 260 2.0E-77 T 29-03-2018 IPR024787 EcsC protein CXR48_RS02290 c67318d79765023fdda539b28d8134eb 268 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 9 263 1.0E-62 T 29-03-2018 CXR48_RS17540 7ccf5b69491c45421433d3be25591271 321 Gene3D G3DSA:3.30.540.10 1 155 5.7E-58 T 29-03-2018 CXR48_RS17540 7ccf5b69491c45421433d3be25591271 321 Gene3D G3DSA:3.30.540.10 156 320 9.1E-57 T 29-03-2018 CXR48_RS17540 7ccf5b69491c45421433d3be25591271 321 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 320 4.7E-164 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CXR48_RS17540 7ccf5b69491c45421433d3be25591271 321 SUPERFAMILY SSF56655 1 312 3.48E-110 T 29-03-2018 CXR48_RS17540 7ccf5b69491c45421433d3be25591271 321 PIRSF PIRSF004532 1 320 7.7E-150 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CXR48_RS17540 7ccf5b69491c45421433d3be25591271 321 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 309 1.3E-141 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CXR48_RS00380 533b223e142744753a58f2b9639e8a19 128 SMART SM00316 4 74 1.9E-26 T 29-03-2018 IPR022967 RNA-binding domain, S1 CXR48_RS00380 533b223e142744753a58f2b9639e8a19 128 Gene3D G3DSA:2.40.50.140 7 120 8.7E-28 T 29-03-2018 CXR48_RS00380 533b223e142744753a58f2b9639e8a19 128 SUPERFAMILY SSF50249 4 84 3.36E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS00380 533b223e142744753a58f2b9639e8a19 128 Pfam PF00575 S1 RNA binding domain 4 74 8.2E-22 T 29-03-2018 IPR003029 S1 domain GO:0003676 CXR48_RS05495 810034de4a3a9d8d6e493b252699da85 258 PIRSF PIRSF000728 1 255 2.3E-87 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CXR48_RS05495 810034de4a3a9d8d6e493b252699da85 258 TIGRFAM TIGR00761 argB: acetylglutamate kinase 4 232 4.8E-83 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CXR48_RS05495 810034de4a3a9d8d6e493b252699da85 258 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 6.2E-5 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS05495 810034de4a3a9d8d6e493b252699da85 258 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 6.2E-5 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS05495 810034de4a3a9d8d6e493b252699da85 258 PRINTS PR00474 Glutamate 5-kinase family signature 32 46 6.2E-5 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CXR48_RS05495 810034de4a3a9d8d6e493b252699da85 258 SUPERFAMILY SSF53633 1 253 5.76E-66 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS05495 810034de4a3a9d8d6e493b252699da85 258 Gene3D G3DSA:3.40.1160.10 1 258 2.1E-54 T 29-03-2018 CXR48_RS05495 810034de4a3a9d8d6e493b252699da85 258 Pfam PF00696 Amino acid kinase family 3 234 2.6E-40 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS05495 810034de4a3a9d8d6e493b252699da85 258 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 252 29.784 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CXR48_RS14780 3eee0edf7cf7035834a3c4a6d99c3620 406 Gene3D G3DSA:1.10.3210.10 199 374 2.5E-21 T 29-03-2018 CXR48_RS14780 3eee0edf7cf7035834a3c4a6d99c3620 406 Gene3D G3DSA:3.20.20.450 2 198 4.5E-19 T 29-03-2018 IPR001633 EAL domain CXR48_RS14780 3eee0edf7cf7035834a3c4a6d99c3620 406 Pfam PF08668 HDOD domain 210 329 5.8E-20 T 29-03-2018 IPR013976 Metal-dependent hydrolase HDOD CXR48_RS14780 3eee0edf7cf7035834a3c4a6d99c3620 406 PIRSF PIRSF003180 1 406 2.4E-147 T 29-03-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing CXR48_RS14780 3eee0edf7cf7035834a3c4a6d99c3620 406 SUPERFAMILY SSF109604 186 404 3.14E-44 T 29-03-2018 CXR48_RS14780 3eee0edf7cf7035834a3c4a6d99c3620 406 Pfam PF00563 EAL domain 46 195 1.5E-9 T 29-03-2018 IPR001633 EAL domain CXR48_RS14780 3eee0edf7cf7035834a3c4a6d99c3620 406 SMART SM00052 2 202 0.008 T 29-03-2018 IPR001633 EAL domain CXR48_RS14780 3eee0edf7cf7035834a3c4a6d99c3620 406 SUPERFAMILY SSF141868 3 198 3.66E-26 T 29-03-2018 IPR001633 EAL domain CXR48_RS02850 39fc2fe0f657110db4ab6cdc296d68f6 247 Pfam PF01925 Sulfite exporter TauE/SafE 4 243 2.1E-40 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CXR48_RS18065 f567ebd80b9965c8c151ffac2512eb2a 86 ProDom PD062384 GERMINATION SPORE TRANSMEMBRANE MEMBRANE MORPHOGENESIS YWCE 1 85 4.0E-40 T 29-03-2018 IPR020185 Spore morphogenesis/germination protein YwcE CXR48_RS18065 f567ebd80b9965c8c151ffac2512eb2a 86 Pfam PF17368 Spore morphogenesis and germination protein YwcE 1 84 7.0E-39 T 29-03-2018 IPR020185 Spore morphogenesis/germination protein YwcE CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 SUPERFAMILY SSF51735 7 259 1.42E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 Pfam PF00106 short chain dehydrogenase 9 202 1.7E-59 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 211 230 6.9E-61 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 87 104 6.9E-61 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 237 256 6.9E-61 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 6.9E-61 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 107 127 6.9E-61 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 172 195 6.9E-61 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 Gene3D G3DSA:3.40.50.720 1 44 1.0E-8 T 29-03-2018 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 Gene3D G3DSA:3.40.50.720 45 261 1.6E-59 T 29-03-2018 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 260 8.1E-115 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CXR48_RS14900 6af4aaeb5ff9b357d6916dbd09f2cc33 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 179 0.0078 T 29-03-2018 CXR48_RS17905 7013fcb2fdaa807451d073e40de96482 245 SUPERFAMILY SSF53448 2 234 4.96E-67 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS17905 7013fcb2fdaa807451d073e40de96482 245 Gene3D G3DSA:3.90.550.10 1 244 2.7E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS17905 7013fcb2fdaa807451d073e40de96482 245 Pfam PF00483 Nucleotidyl transferase 2 232 1.8E-50 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Pfam PF01464 Transglycosylase SLT domain 1398 1521 3.1E-20 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 SUPERFAMILY SSF53955 1391 1482 3.97E-12 T 29-03-2018 IPR023346 Lysozyme-like domain CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 253 278 1.5E-9 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 495 534 7.0E-7 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 442 468 1.0E-9 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 415 441 2.6E-10 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 387 414 8.6E-10 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 334 359 2.2E-10 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 360 386 1.1E-9 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 279 306 2.8E-9 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 469 494 1.1E-8 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 222 252 6.1E-6 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.5.120 307 333 8.6E-10 T 29-03-2018 IPR003185 Proteasome activator pa28, N-terminal domain GO:0008537 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.10.530.10 1309 1527 7.3E-15 T 29-03-2018 CXR48_RS06300 476a024c0e70f445f4915ba66d193726 1627 Gene3D G3DSA:1.20.120.20 826 1019 6.5E-16 T 29-03-2018 CXR48_RS09585 19881cf1b5e0f8514e3891b00a230e91 638 Pfam PF00092 von Willebrand factor type A domain 447 624 7.9E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS09585 19881cf1b5e0f8514e3891b00a230e91 638 SMART SM00327 442 633 6.1E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS09585 19881cf1b5e0f8514e3891b00a230e91 638 SUPERFAMILY SSF53300 446 631 4.75E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS09585 19881cf1b5e0f8514e3891b00a230e91 638 Gene3D G3DSA:3.40.50.410 441 638 9.9E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS17480 e6876044ecb6b99c96f88c277f0b8137 226 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 40 165 1.1E-49 T 29-03-2018 IPR014202 Sporulation stage II, protein R CXR48_RS17480 e6876044ecb6b99c96f88c277f0b8137 226 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 3 170 3.9E-71 T 29-03-2018 IPR014202 Sporulation stage II, protein R CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 30 477 4.9E-171 T 29-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 Gene3D G3DSA:3.40.50.980 155 301 6.8E-40 T 29-03-2018 CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 Gene3D G3DSA:3.30.300.30 386 486 1.4E-27 T 29-03-2018 CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 Gene3D G3DSA:3.40.50.980 3 154 6.9E-39 T 29-03-2018 CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 SUPERFAMILY SSF56801 6 483 8.37E-143 T 29-03-2018 CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 Gene3D G3DSA:2.30.38.10 302 383 3.2E-24 T 29-03-2018 CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 Pfam PF00501 AMP-binding enzyme 11 390 1.4E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 5 481 50.199 T 29-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CXR48_RS14240 c80a1000f172872e336111d9e23fcb30 487 Pfam PF13193 AMP-binding enzyme C-terminal domain 399 472 3.1E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS13285 77bdee62e204ad71bafa8d3811e407b2 394 Hamap MF_00497_B Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 3 384 57.471 T 29-03-2018 IPR023003 Glycerol-1-phosphate dehydrogenase, bacteria GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CXR48_RS13285 77bdee62e204ad71bafa8d3811e407b2 394 Gene3D G3DSA:1.20.1090.10 179 386 6.9E-31 T 29-03-2018 CXR48_RS13285 77bdee62e204ad71bafa8d3811e407b2 394 Pfam PF13685 Iron-containing alcohol dehydrogenase 28 295 7.8E-72 T 29-03-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CXR48_RS13285 77bdee62e204ad71bafa8d3811e407b2 394 Gene3D G3DSA:3.40.50.1970 6 178 1.5E-23 T 29-03-2018 CXR48_RS13285 77bdee62e204ad71bafa8d3811e407b2 394 SUPERFAMILY SSF56796 22 384 9.68E-60 T 29-03-2018 CXR48_RS08245 560be402083f79632e5a57f3b86a6a33 260 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 204 221 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CXR48_RS08245 560be402083f79632e5a57f3b86a6a33 260 Gene3D G3DSA:3.40.1180.10 17 260 3.4E-95 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CXR48_RS08245 560be402083f79632e5a57f3b86a6a33 260 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 31 259 40.556 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CXR48_RS08245 560be402083f79632e5a57f3b86a6a33 260 SUPERFAMILY SSF64005 29 253 4.84E-88 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CXR48_RS08245 560be402083f79632e5a57f3b86a6a33 260 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 31 258 2.4E-88 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CXR48_RS08245 560be402083f79632e5a57f3b86a6a33 260 Pfam PF01255 Putative undecaprenyl diphosphate synthase 38 258 8.2E-84 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CXR48_RS14415 b5000da60d1e888eee3d681908db4d61 193 Pfam PF03473 MOSC domain 62 175 1.2E-4 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CXR48_RS14415 b5000da60d1e888eee3d681908db4d61 193 Gene3D G3DSA:2.40.33.20 1 192 2.8E-25 T 29-03-2018 CXR48_RS14415 b5000da60d1e888eee3d681908db4d61 193 SUPERFAMILY SSF50800 1 179 1.05E-46 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CXR48_RS16705 a101d62f0ea8df04ed239945336581d1 461 SMART SM00490 341 422 9.5E-11 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS16705 a101d62f0ea8df04ed239945336581d1 461 Pfam PF04851 Type III restriction enzyme, res subunit 118 266 1.0E-8 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CXR48_RS16705 a101d62f0ea8df04ed239945336581d1 461 Pfam PF00271 Helicase conserved C-terminal domain 327 421 1.3E-11 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS16705 a101d62f0ea8df04ed239945336581d1 461 SUPERFAMILY SSF52540 133 268 3.14E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16705 a101d62f0ea8df04ed239945336581d1 461 SUPERFAMILY SSF52540 295 432 3.14E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16705 a101d62f0ea8df04ed239945336581d1 461 Gene3D G3DSA:3.40.50.300 101 290 5.1E-20 T 29-03-2018 CXR48_RS16705 a101d62f0ea8df04ed239945336581d1 461 SMART SM00487 115 299 8.8E-18 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS16705 a101d62f0ea8df04ed239945336581d1 461 Gene3D G3DSA:3.40.50.300 302 459 3.9E-19 T 29-03-2018 CXR48_RS00870 0d2715c142930f3e946f1b15ea062c80 131 SUPERFAMILY SSF53137 16 131 2.55E-49 T 29-03-2018 CXR48_RS00870 0d2715c142930f3e946f1b15ea062c80 131 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 12 128 2.3E-58 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00870 0d2715c142930f3e946f1b15ea062c80 131 ProSitePatterns PS00054 Ribosomal protein S11 signature. 99 121 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site CXR48_RS00870 0d2715c142930f3e946f1b15ea062c80 131 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 5 131 34.428 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00870 0d2715c142930f3e946f1b15ea062c80 131 Pfam PF00411 Ribosomal protein S11 21 130 8.0E-52 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00870 0d2715c142930f3e946f1b15ea062c80 131 Gene3D G3DSA:3.30.420.80 4 131 1.6E-43 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00870 0d2715c142930f3e946f1b15ea062c80 131 PIRSF PIRSF002131 1 131 1.6E-53 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CXR48_RS04515 f88158bf66b64ca416cfad7c8c110d4a 125 SMART SM00345 15 74 1.5E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS04515 f88158bf66b64ca416cfad7c8c110d4a 125 Gene3D G3DSA:1.10.10.10 7 71 2.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04515 f88158bf66b64ca416cfad7c8c110d4a 125 Gene3D G3DSA:1.10.287.100 77 116 0.0028 T 29-03-2018 CXR48_RS04515 f88158bf66b64ca416cfad7c8c110d4a 125 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 5.1E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS04515 f88158bf66b64ca416cfad7c8c110d4a 125 SUPERFAMILY SSF46785 5 78 1.71E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05435 407868b45b169f524b5614d4ba4c0431 283 SUPERFAMILY SSF82549 1 282 2.12E-88 T 29-03-2018 CXR48_RS05435 407868b45b169f524b5614d4ba4c0431 283 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 280 8.5E-95 T 29-03-2018 IPR003797 DegV CXR48_RS05435 407868b45b169f524b5614d4ba4c0431 283 Gene3D G3DSA:3.40.50.10170 1 156 1.0E-45 T 29-03-2018 CXR48_RS05435 407868b45b169f524b5614d4ba4c0431 283 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 1.5E-88 T 29-03-2018 IPR003797 DegV CXR48_RS05435 407868b45b169f524b5614d4ba4c0431 283 Gene3D G3DSA:3.30.1180.10 157 282 4.8E-41 T 29-03-2018 CXR48_RS12005 cf4420e40c83e14f017ad261bdaecb28 715 Gene3D G3DSA:3.90.1310.10 34 320 8.9E-36 T 29-03-2018 CXR48_RS12005 cf4420e40c83e14f017ad261bdaecb28 715 SUPERFAMILY SSF56601 320 667 3.94E-68 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS12005 cf4420e40c83e14f017ad261bdaecb28 715 Gene3D G3DSA:3.40.710.10 321 699 6.4E-80 T 29-03-2018 CXR48_RS12005 cf4420e40c83e14f017ad261bdaecb28 715 Pfam PF00905 Penicillin binding protein transpeptidase domain 353 679 2.9E-78 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS12005 cf4420e40c83e14f017ad261bdaecb28 715 SUPERFAMILY SSF56519 187 319 2.35E-36 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS12005 cf4420e40c83e14f017ad261bdaecb28 715 SUPERFAMILY SSF56519 63 123 2.35E-36 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS12005 cf4420e40c83e14f017ad261bdaecb28 715 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 304 5.8E-36 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS05285 383e714df57ac0bfa27e5c97cb545cc0 390 SUPERFAMILY SSF56300 1 329 2.35E-55 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS05285 383e714df57ac0bfa27e5c97cb545cc0 390 Pfam PF00149 Calcineurin-like phosphoesterase 1 96 6.3E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CXR48_RS05285 383e714df57ac0bfa27e5c97cb545cc0 390 Gene3D G3DSA:3.60.21.10 1 72 5.9E-14 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS05285 383e714df57ac0bfa27e5c97cb545cc0 390 Gene3D G3DSA:3.60.21.10 73 276 7.8E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS05285 383e714df57ac0bfa27e5c97cb545cc0 390 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 252 2.2E-84 T 29-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CXR48_RS05285 383e714df57ac0bfa27e5c97cb545cc0 390 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 276 364 1.5E-5 T 29-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CXR48_RS11415 dc28156cd3cc19878d4c4c31f06c1519 338 Hamap MF_01614 NADPH dehydrogenase [namA]. 2 338 68.223 T 29-03-2018 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 CXR48_RS11415 dc28156cd3cc19878d4c4c31f06c1519 338 SUPERFAMILY SSF51395 4 335 7.57E-115 T 29-03-2018 CXR48_RS11415 dc28156cd3cc19878d4c4c31f06c1519 338 Gene3D G3DSA:3.20.20.70 1 338 5.2E-119 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS11415 dc28156cd3cc19878d4c4c31f06c1519 338 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 326 5.8E-106 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CXR48_RS16110 757da3f4a42cab5c074bfc074eb3ebc0 396 Pfam PF00155 Aminotransferase class I and II 73 383 1.5E-23 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS16110 757da3f4a42cab5c074bfc074eb3ebc0 396 Gene3D G3DSA:3.90.1150.10 299 396 1.3E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS16110 757da3f4a42cab5c074bfc074eb3ebc0 396 Gene3D G3DSA:3.40.640.10 47 298 7.1E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS16110 757da3f4a42cab5c074bfc074eb3ebc0 396 SUPERFAMILY SSF53383 28 393 2.53E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS07530 20fdc96ae3327985fb5cf0107f283042 160 PIRSF PIRSF037732 1 160 1.5E-89 T 29-03-2018 IPR017274 Putative N-acetyltransferase YlbP CXR48_RS07530 20fdc96ae3327985fb5cf0107f283042 160 Pfam PF00583 Acetyltransferase (GNAT) family 27 104 3.5E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS07530 20fdc96ae3327985fb5cf0107f283042 160 SUPERFAMILY SSF55729 19 141 9.64E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS07530 20fdc96ae3327985fb5cf0107f283042 160 Hamap MF_00824 Uncharacterized N-acetyltransferase . 1 148 41.386 T 29-03-2018 IPR017274 Putative N-acetyltransferase YlbP CXR48_RS07530 20fdc96ae3327985fb5cf0107f283042 160 Gene3D G3DSA:3.40.630.30 1 160 6.1E-26 T 29-03-2018 CXR48_RS18190 b102845d7f1c7853e60e7902cab89edc 444 PIRSF PIRSF006351 1 443 2.3E-153 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS18190 b102845d7f1c7853e60e7902cab89edc 444 Pfam PF02378 Phosphotransferase system, EIIC 29 359 3.5E-76 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS18190 b102845d7f1c7853e60e7902cab89edc 444 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 434 1.2E-204 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CXR48_RS18190 b102845d7f1c7853e60e7902cab89edc 444 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 434 1.2E-204 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS12640 cf9930f434e3eeb5ffd013fc032063ee 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 216 3.2E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS12640 cf9930f434e3eeb5ffd013fc032063ee 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 109 2.1E-28 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CXR48_RS12640 cf9930f434e3eeb5ffd013fc032063ee 218 Gene3D G3DSA:1.10.3720.10 5 218 1.1E-40 T 29-03-2018 CXR48_RS12640 cf9930f434e3eeb5ffd013fc032063ee 218 SUPERFAMILY SSF161098 15 203 6.28E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS03490 5ea14dcfe12e3337c6515fa743f2bef7 82 Pfam PF11007 Spore coat associated protein JA (CotJA) 33 68 2.3E-12 T 29-03-2018 IPR020256 Spore coat protein CotJA CXR48_RS03490 5ea14dcfe12e3337c6515fa743f2bef7 82 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 10 75 7.0E-30 T 29-03-2018 IPR020256 Spore coat protein CotJA CXR48_RS15300 f91c22757facab00f4f897d43ea155ca 222 Gene3D G3DSA:1.10.3720.10 10 222 2.3E-38 T 29-03-2018 CXR48_RS15300 f91c22757facab00f4f897d43ea155ca 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 222 1.1E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15300 f91c22757facab00f4f897d43ea155ca 222 SUPERFAMILY SSF161098 13 209 3.27E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS11475 21db0d5bcd0174dcd12f852d453213f5 176 Pfam PF03734 L,D-transpeptidase catalytic domain 27 150 7.8E-21 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CXR48_RS11475 21db0d5bcd0174dcd12f852d453213f5 176 Gene3D G3DSA:2.40.440.10 21 152 9.4E-30 T 29-03-2018 CXR48_RS11475 21db0d5bcd0174dcd12f852d453213f5 176 SUPERFAMILY SSF141523 23 151 4.19E-31 T 29-03-2018 CXR48_RS12170 91fcc70baeb81a4388f0c8f3fe23add3 319 Pfam PF02562 PhoH-like protein 113 316 8.7E-96 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CXR48_RS12170 91fcc70baeb81a4388f0c8f3fe23add3 319 Gene3D G3DSA:3.40.50.300 111 316 3.9E-32 T 29-03-2018 CXR48_RS12170 91fcc70baeb81a4388f0c8f3fe23add3 319 SUPERFAMILY SSF52540 61 278 5.15E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08125 14f054709d70c70dc984ae938e204cfc 71 Pfam PF06289 Flagellar protein (FlbD) 1 58 1.7E-26 T 29-03-2018 IPR009384 Flagellar CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 Pfam PF01842 ACT domain 351 416 4.9E-13 T 29-03-2018 IPR002912 ACT domain CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 PIRSF PIRSF000098 1 430 2.1E-178 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 SUPERFAMILY SSF55347 137 302 6.54E-54 T 29-03-2018 CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 Gene3D G3DSA:3.30.70.260 345 426 2.4E-14 T 29-03-2018 CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 SUPERFAMILY SSF55021 349 422 7.33E-11 T 29-03-2018 CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 3.7E-29 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 Gene3D G3DSA:3.30.360.10 158 298 7.9E-54 T 29-03-2018 CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 SUPERFAMILY SSF51735 3 158 6.33E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 Pfam PF00742 Homoserine dehydrogenase 137 315 4.7E-66 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CXR48_RS15070 0fed8c362acea35ae93984fd38d63eed 433 Gene3D G3DSA:3.40.50.720 2 157 8.9E-35 T 29-03-2018 CXR48_RS06155 09d63519a96a9d647d214ed77fb6f0b5 254 Pfam PF01925 Sulfite exporter TauE/SafE 6 253 3.8E-45 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CXR48_RS13155 378d97d5d8f0e0bea7e67203d1356e90 104 Pfam PF00085 Thioredoxin 3 103 9.9E-31 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CXR48_RS13155 378d97d5d8f0e0bea7e67203d1356e90 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CXR48_RS13155 378d97d5d8f0e0bea7e67203d1356e90 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 103 8.5E-40 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CXR48_RS13155 378d97d5d8f0e0bea7e67203d1356e90 104 PRINTS PR00421 Thioredoxin family signature 20 28 1.3E-8 T 29-03-2018 CXR48_RS13155 378d97d5d8f0e0bea7e67203d1356e90 104 PRINTS PR00421 Thioredoxin family signature 68 79 1.3E-8 T 29-03-2018 CXR48_RS13155 378d97d5d8f0e0bea7e67203d1356e90 104 PRINTS PR00421 Thioredoxin family signature 28 37 1.3E-8 T 29-03-2018 CXR48_RS13155 378d97d5d8f0e0bea7e67203d1356e90 104 SUPERFAMILY SSF52833 3 104 4.02E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS13155 378d97d5d8f0e0bea7e67203d1356e90 104 PIRSF PIRSF000077 1 104 8.3E-43 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CXR48_RS13155 378d97d5d8f0e0bea7e67203d1356e90 104 Gene3D G3DSA:3.40.30.10 1 104 5.3E-35 T 29-03-2018 CXR48_RS10300 5f84a9af253569e0b8d223e9803e078e 430 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 10 409 8.9E-83 T 29-03-2018 IPR024455 Phage capsid CXR48_RS10300 5f84a9af253569e0b8d223e9803e078e 430 Pfam PF05065 Phage capsid family 134 408 7.6E-62 T 29-03-2018 IPR024455 Phage capsid CXR48_RS10300 5f84a9af253569e0b8d223e9803e078e 430 SUPERFAMILY SSF56563 126 409 9.81E-64 T 29-03-2018 CXR48_RS10300 5f84a9af253569e0b8d223e9803e078e 430 Gene3D G3DSA:3.30.2400.10 155 298 2.3E-23 T 29-03-2018 CXR48_RS13085 15b70604ee2df2f89c8400d3e9d03c25 198 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 5 198 49.596 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CXR48_RS13085 15b70604ee2df2f89c8400d3e9d03c25 198 Gene3D G3DSA:3.90.950.10 2 198 3.3E-80 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CXR48_RS13085 15b70604ee2df2f89c8400d3e9d03c25 198 Pfam PF01725 Ham1 family 8 194 6.9E-62 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CXR48_RS13085 15b70604ee2df2f89c8400d3e9d03c25 198 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 7 196 5.4E-72 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CXR48_RS13085 15b70604ee2df2f89c8400d3e9d03c25 198 SUPERFAMILY SSF52972 4 196 3.92E-70 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CXR48_RS16685 359e890d78d14c6f00d3a098147a5d51 88 SUPERFAMILY SSF101498 1 85 2.48E-19 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CXR48_RS16685 359e890d78d14c6f00d3a098147a5d51 88 Gene3D G3DSA:1.10.287.1160 54 83 2.7E-12 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CXR48_RS16685 359e890d78d14c6f00d3a098147a5d51 88 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 86 7.6E-19 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CXR48_RS16685 359e890d78d14c6f00d3a098147a5d51 88 Pfam PF04316 Anti-sigma-28 factor, FlgM 32 83 1.3E-16 T 29-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal CXR48_RS17325 743f12bd8c9ce581c8cdec41de2b6aa3 124 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 103 2.4E-49 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17325 743f12bd8c9ce581c8cdec41de2b6aa3 124 Pfam PF00699 Urease beta subunit 3 98 2.8E-41 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17325 743f12bd8c9ce581c8cdec41de2b6aa3 124 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 28.702 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17325 743f12bd8c9ce581c8cdec41de2b6aa3 124 SUPERFAMILY SSF51278 1 120 9.03E-47 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS17325 743f12bd8c9ce581c8cdec41de2b6aa3 124 Gene3D G3DSA:2.10.150.10 1 101 1.5E-42 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CXR48_RS02105 4617676d9446ee4bc4606fb1cdf63292 243 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 11 219 1.1E-75 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CXR48_RS02105 4617676d9446ee4bc4606fb1cdf63292 243 Gene3D G3DSA:2.40.100.10 104 237 1.7E-53 T 29-03-2018 IPR029000 Cyclophilin-like domain CXR48_RS02105 4617676d9446ee4bc4606fb1cdf63292 243 Gene3D G3DSA:3.30.1360.40 10 103 1.0E-20 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CXR48_RS02105 4617676d9446ee4bc4606fb1cdf63292 243 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 16 228 1.1E-85 T 29-03-2018 IPR010016 KipI family CXR48_RS02105 4617676d9446ee4bc4606fb1cdf63292 243 SUPERFAMILY SSF160467 12 110 1.44E-16 T 29-03-2018 CXR48_RS02105 4617676d9446ee4bc4606fb1cdf63292 243 SUPERFAMILY SSF50891 106 235 7.59E-49 T 29-03-2018 IPR029000 Cyclophilin-like domain CXR48_RS02105 4617676d9446ee4bc4606fb1cdf63292 243 SMART SM00796 10 219 6.1E-103 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CXR48_RS16240 65d7c317b8a2ecc8b08ab40952da060d 162 Pfam PF05870 Phenolic acid decarboxylase (PAD) 1 158 4.1E-82 T 29-03-2018 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 CXR48_RS16240 65d7c317b8a2ecc8b08ab40952da060d 162 PIRSF PIRSF011561 1 162 7.9E-97 T 29-03-2018 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 CXR48_RS16240 65d7c317b8a2ecc8b08ab40952da060d 162 ProDom PD022010 DECARBOXYLASE ACID PHENOLIC P-COUMARIC LYASE 4.1.1.- PAD PADC FERULATE PROBABLE 1 161 5.0E-86 T 29-03-2018 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 CXR48_RS16240 65d7c317b8a2ecc8b08ab40952da060d 162 SUPERFAMILY SSF50814 2 160 4.78E-75 T 29-03-2018 IPR012674 Calycin CXR48_RS16240 65d7c317b8a2ecc8b08ab40952da060d 162 Gene3D G3DSA:2.40.128.20 2 154 2.2E-62 T 29-03-2018 IPR012674 Calycin CXR48_RS15635 d946948c35d65315e6036ab230215545 308 Pfam PF12728 Helix-turn-helix domain 7 54 5.3E-14 T 29-03-2018 CXR48_RS15635 d946948c35d65315e6036ab230215545 308 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 53 2.4E-17 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CXR48_RS15635 d946948c35d65315e6036ab230215545 308 SUPERFAMILY SSF53850 122 296 1.32E-12 T 29-03-2018 CXR48_RS15635 d946948c35d65315e6036ab230215545 308 Gene3D G3DSA:3.40.190.10 162 278 1.2E-8 T 29-03-2018 CXR48_RS15635 d946948c35d65315e6036ab230215545 308 Pfam PF12727 PBP superfamily domain 107 281 9.2E-51 T 29-03-2018 IPR024370 PBP domain CXR48_RS15635 d946948c35d65315e6036ab230215545 308 SUPERFAMILY SSF46955 7 55 7.32E-6 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS15635 d946948c35d65315e6036ab230215545 308 Gene3D G3DSA:1.10.10.10 8 65 5.6E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06025 a961a23527da92160038e5a737120347 406 SUPERFAMILY SSF48264 24 393 1.02E-91 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00385 P450 superfamily signature 240 257 2.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00385 P450 superfamily signature 275 286 2.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00385 P450 superfamily signature 350 361 2.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00385 P450 superfamily signature 341 350 2.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 Pfam PF00067 Cytochrome P450 46 385 8.8E-37 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 Gene3D G3DSA:1.10.630.10 1 404 1.7E-77 T 29-03-2018 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00359 B-class P450 signature 350 361 2.5E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00359 B-class P450 signature 292 319 2.5E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00359 B-class P450 signature 148 163 2.5E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00359 B-class P450 signature 131 147 2.5E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00359 B-class P450 signature 194 216 2.5E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00359 B-class P450 signature 341 350 2.5E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00359 B-class P450 signature 85 96 2.5E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00359 B-class P450 signature 275 286 2.5E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS06025 a961a23527da92160038e5a737120347 406 PRINTS PR00359 B-class P450 signature 320 335 2.5E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CXR48_RS17570 22ad45b6582f92f5df768c2fc289f076 535 Gene3D G3DSA:3.40.50.880 287 535 1.0E-74 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS17570 22ad45b6582f92f5df768c2fc289f076 535 Pfam PF06418 CTP synthase N-terminus 3 267 1.2E-130 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CXR48_RS17570 22ad45b6582f92f5df768c2fc289f076 535 Hamap MF_01227 CTP synthase [pyrG]. 2 532 53.274 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CXR48_RS17570 22ad45b6582f92f5df768c2fc289f076 535 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 1.2E-270 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CXR48_RS17570 22ad45b6582f92f5df768c2fc289f076 535 Gene3D G3DSA:3.40.50.300 1 286 3.1E-135 T 29-03-2018 CXR48_RS17570 22ad45b6582f92f5df768c2fc289f076 535 SUPERFAMILY SSF52317 290 532 1.74E-85 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS17570 22ad45b6582f92f5df768c2fc289f076 535 Pfam PF00117 Glutamine amidotransferase class-I 302 525 2.3E-60 T 29-03-2018 IPR017926 Glutamine amidotransferase CXR48_RS17570 22ad45b6582f92f5df768c2fc289f076 535 SUPERFAMILY SSF52540 1 271 2.3E-127 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 SUPERFAMILY SSF48256 3 363 5.5E-113 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 Pfam PF00285 Citrate synthase, C-terminal domain 7 357 8.8E-106 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 ProSitePatterns PS00480 Citrate synthase signature. 256 269 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 Gene3D G3DSA:1.10.580.10 1 255 2.0E-69 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 PRINTS PR00143 Citrate synthase signature 249 269 1.4E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 PRINTS PR00143 Citrate synthase signature 307 323 1.4E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 PRINTS PR00143 Citrate synthase signature 174 189 1.4E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 PRINTS PR00143 Citrate synthase signature 327 341 1.4E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 PRINTS PR00143 Citrate synthase signature 125 138 1.4E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 PRINTS PR00143 Citrate synthase signature 196 224 1.4E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 PIRSF PIRSF001369 1 365 9.9E-130 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CXR48_RS11565 92b8f1aafeecf349799037bc174a4d8c 365 Gene3D G3DSA:1.10.580.10 295 354 7.2E-7 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CXR48_RS11130 d33d5f4af84b06fcdab5c758ea5c0afc 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 106 6.1E-39 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CXR48_RS11130 d33d5f4af84b06fcdab5c758ea5c0afc 117 Gene3D G3DSA:3.30.750.24 7 115 2.3E-25 T 29-03-2018 IPR002645 STAS domain CXR48_RS11130 d33d5f4af84b06fcdab5c758ea5c0afc 117 Pfam PF01740 STAS domain 6 109 1.9E-25 T 29-03-2018 IPR002645 STAS domain CXR48_RS11130 d33d5f4af84b06fcdab5c758ea5c0afc 117 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 5 110 2.0E-47 T 29-03-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 CXR48_RS11130 d33d5f4af84b06fcdab5c758ea5c0afc 117 SUPERFAMILY SSF52091 4 113 4.91E-31 T 29-03-2018 IPR002645 STAS domain CXR48_RS15890 ae0a61af700d6897c9d9f2e94858e8af 225 SUPERFAMILY SSF161098 17 199 2.35E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15890 ae0a61af700d6897c9d9f2e94858e8af 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 209 1.4E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15890 ae0a61af700d6897c9d9f2e94858e8af 225 Gene3D G3DSA:1.10.3720.10 2 215 1.8E-30 T 29-03-2018 CXR48_RS00655 620ef5a1eb1571a091befd61d2fa1cb5 59 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 6 34 - T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CXR48_RS00655 620ef5a1eb1571a091befd61d2fa1cb5 59 Gene3D G3DSA:1.20.5.1030 3 54 2.6E-21 T 29-03-2018 CXR48_RS00655 620ef5a1eb1571a091befd61d2fa1cb5 59 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 3 58 6.2E-24 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CXR48_RS00655 620ef5a1eb1571a091befd61d2fa1cb5 59 Hamap MF_00422 Protein translocase subunit SecE [secE]. 1 56 12.738 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CXR48_RS00655 620ef5a1eb1571a091befd61d2fa1cb5 59 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 5 57 1.7E-20 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CXR48_RS11695 fc27b32cab3e6d4535e19baefe039ba7 159 Gene3D G3DSA:2.40.50.100 117 158 2.7E-15 T 29-03-2018 CXR48_RS11695 fc27b32cab3e6d4535e19baefe039ba7 159 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 113 130 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CXR48_RS11695 fc27b32cab3e6d4535e19baefe039ba7 159 Pfam PF00364 Biotin-requiring enzyme 83 154 7.6E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CXR48_RS11695 fc27b32cab3e6d4535e19baefe039ba7 159 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 2 157 3.9E-59 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CXR48_RS11695 fc27b32cab3e6d4535e19baefe039ba7 159 SUPERFAMILY SSF51230 80 156 2.09E-22 T 29-03-2018 IPR011053 Single hybrid motif CXR48_RS11695 fc27b32cab3e6d4535e19baefe039ba7 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 118 131 1.4E-14 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CXR48_RS11695 fc27b32cab3e6d4535e19baefe039ba7 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 86 99 1.4E-14 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CXR48_RS11695 fc27b32cab3e6d4535e19baefe039ba7 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 103 117 1.4E-14 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CXR48_RS11695 fc27b32cab3e6d4535e19baefe039ba7 159 Gene3D G3DSA:2.40.50.100 81 116 0.0061 T 29-03-2018 CXR48_RS19090 943879c71d23eee23f76421bb35a7c97 47 Pfam PF14174 YycC-like protein 1 45 2.4E-24 T 29-03-2018 IPR025550 YycC-like protein CXR48_RS00640 f46efb9257f54ae545a89ac35f75a17d 170 Pfam PF05991 YacP-like NYN domain 4 166 1.5E-56 T 29-03-2018 IPR010298 Protein of unknown function DUF901 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 PRINTS PR00834 HtrA/DegQ protease family signature 176 188 1.1E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 PRINTS PR00834 HtrA/DegQ protease family signature 197 217 1.1E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 PRINTS PR00834 HtrA/DegQ protease family signature 279 296 1.1E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 PRINTS PR00834 HtrA/DegQ protease family signature 238 262 1.1E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 PRINTS PR00834 HtrA/DegQ protease family signature 301 318 1.1E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 PRINTS PR00834 HtrA/DegQ protease family signature 393 405 1.1E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 SUPERFAMILY SSF50494 121 343 3.17E-57 T 29-03-2018 IPR009003 Peptidase S1, PA clan CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 Pfam PF13365 Trypsin-like peptidase domain 164 308 7.2E-31 T 29-03-2018 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 SMART SM00228 346 436 5.8E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 Gene3D G3DSA:2.30.42.10 349 453 6.9E-26 T 29-03-2018 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 Gene3D G3DSA:2.40.10.10 239 348 1.1E-36 T 29-03-2018 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 Gene3D G3DSA:2.40.10.10 119 238 4.9E-30 T 29-03-2018 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 Pfam PF13180 PDZ domain 346 445 1.0E-19 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 SUPERFAMILY SSF50156 370 449 1.13E-21 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS15435 d77c553b18f120d178ff0477336ae54b 453 SUPERFAMILY SSF50156 298 325 1.13E-21 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS05445 524e80763518b7f85ae5425e72558fd9 153 ProDom PD076312 INHIBITOR INTRACELLULAR PROTEINASE PRECURSOR SIGNAL DOMAIN SLH S-LAYER PROTEASE BSUPI 34 152 5.0E-28 T 29-03-2018 IPR020481 Intracellular proteinase inhibitor BsuPI CXR48_RS05445 524e80763518b7f85ae5425e72558fd9 153 Pfam PF12690 Intracellular proteinase inhibitor 52 128 2.0E-26 T 29-03-2018 IPR020481 Intracellular proteinase inhibitor BsuPI CXR48_RS05445 524e80763518b7f85ae5425e72558fd9 153 Gene3D G3DSA:2.60.40.10 32 152 5.2E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS10010 1d2669a05c2fa4916349d40cae6d3da8 83 Pfam PF10751 Protein of unknown function (DUF2535) 1 83 8.4E-36 T 29-03-2018 IPR019687 Protein of unknown function DUF2535 CXR48_RS14040 0472019f10f8dfed29ecb07cacabcea0 436 Pfam PF02687 FtsX-like permease family 324 427 1.9E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CXR48_RS14040 0472019f10f8dfed29ecb07cacabcea0 436 Pfam PF12704 MacB-like periplasmic core domain 22 267 1.7E-11 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CXR48_RS18365 58bb5b0955decff4562231837afaeb96 452 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 11 428 1.1E-106 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CXR48_RS18365 58bb5b0955decff4562231837afaeb96 452 PIRSF PIRSF002744 1 451 4.8E-141 T 29-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CXR48_RS14510 4304e6318fcb79e319b6eae1c2bd02c2 245 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 245 49.33 T 29-03-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 CXR48_RS14510 4304e6318fcb79e319b6eae1c2bd02c2 245 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 1 244 4.0E-106 T 29-03-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 CXR48_RS13875 61cb58fefc52793df1cdb236e9332428 92 Pfam PF14165 YtzH-like protein 3 88 3.3E-36 T 29-03-2018 IPR025547 YtzH-like protein CXR48_RS04835 a3f783d2e8e6d15b6d85dbd95c347216 206 Pfam PF13460 NAD(P)H-binding 7 192 2.0E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS04835 a3f783d2e8e6d15b6d85dbd95c347216 206 Gene3D G3DSA:3.40.50.720 1 206 7.6E-18 T 29-03-2018 CXR48_RS04835 a3f783d2e8e6d15b6d85dbd95c347216 206 SUPERFAMILY SSF51735 1 204 5.83E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS05750 f23606b1113ea43196a777aa1dcbaeff 336 Gene3D G3DSA:3.40.50.720 1 243 7.5E-61 T 29-03-2018 CXR48_RS05750 f23606b1113ea43196a777aa1dcbaeff 336 SUPERFAMILY SSF69572 3 327 6.54E-80 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CXR48_RS05750 f23606b1113ea43196a777aa1dcbaeff 336 Pfam PF00899 ThiF family 5 239 1.2E-55 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 SMART SM00662 20 227 3.9E-102 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 1.0E-25 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 Gene3D G3DSA:3.30.1360.10 1 112 7.0E-19 T 29-03-2018 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 Gene3D G3DSA:3.30.1360.10 113 224 5.1E-26 T 29-03-2018 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 SUPERFAMILY SSF47789 247 313 7.85E-25 T 29-03-2018 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 6.6E-23 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.104 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 SUPERFAMILY SSF56553 50 171 9.94E-44 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 4.5E-24 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 313 7.7E-125 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 1.9E-29 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 SUPERFAMILY SSF55257 146 230 8.04E-31 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 SUPERFAMILY SSF55257 5 54 8.04E-31 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00875 773cf736d127e9b0d9cda0ea8cd8557b 314 Gene3D G3DSA:1.10.150.20 241 314 1.2E-27 T 29-03-2018 CXR48_RS05140 31f2a18d232a63522b8e204076eac18e 292 Gene3D G3DSA:3.40.50.1980 17 130 1.0E-18 T 29-03-2018 CXR48_RS05140 31f2a18d232a63522b8e204076eac18e 292 Gene3D G3DSA:3.40.50.1980 131 288 2.4E-26 T 29-03-2018 CXR48_RS05140 31f2a18d232a63522b8e204076eac18e 292 SUPERFAMILY SSF53807 28 282 5.49E-48 T 29-03-2018 CXR48_RS05140 31f2a18d232a63522b8e204076eac18e 292 Pfam PF01497 Periplasmic binding protein 44 261 9.4E-23 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CXR48_RS19195 cfc3ad3134b4972dd34e9477b1370eca 122 Pfam PF06993 Protein of unknown function (DUF1304) 11 120 1.6E-40 T 29-03-2018 IPR009732 Protein of unknown function DUF1304 CXR48_RS03470 54734b264bfe88eeb7cd3cf55fbd71ce 668 Pfam PF04740 LXG domain of WXG superfamily 2 200 2.3E-48 T 29-03-2018 IPR006829 LXG domain CXR48_RS03470 54734b264bfe88eeb7cd3cf55fbd71ce 668 Pfam PF13930 DNA/RNA non-specific endonuclease 525 653 7.4E-42 T 29-03-2018 CXR48_RS08330 08e93ff0b8d8a8548ef0e313e82c0146 319 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 46 313 6.7E-143 T 29-03-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY CXR48_RS08330 08e93ff0b8d8a8548ef0e313e82c0146 319 Gene3D G3DSA:3.20.20.370 85 317 5.1E-53 T 29-03-2018 CXR48_RS08330 08e93ff0b8d8a8548ef0e313e82c0146 319 Pfam PF12229 Putative peptidoglycan binding domain 39 92 9.0E-5 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain CXR48_RS08330 08e93ff0b8d8a8548ef0e313e82c0146 319 SUPERFAMILY SSF88713 110 313 4.0E-58 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CXR48_RS08330 08e93ff0b8d8a8548ef0e313e82c0146 319 Pfam PF01522 Polysaccharide deacetylase 126 245 1.4E-26 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CXR48_RS14845 040e313c3b54f0e1cb91d09bece659c0 428 Pfam PF10140 WXG100 protein secretion system (Wss), protein YukC 28 382 4.5E-128 T 29-03-2018 IPR018778 Type VII secretion system EssB CXR48_RS14845 040e313c3b54f0e1cb91d09bece659c0 428 TIGRFAM TIGR03926 T7_EssB: type VII secretion protein EssB 8 382 5.0E-131 T 29-03-2018 IPR018778 Type VII secretion system EssB CXR48_RS01460 ee3615a7e3533088332c0076faa30b32 479 Pfam PF07690 Major Facilitator Superfamily 22 414 8.6E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS01460 ee3615a7e3533088332c0076faa30b32 479 SUPERFAMILY SSF103473 11 198 8.76E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01460 ee3615a7e3533088332c0076faa30b32 479 SUPERFAMILY SSF103473 253 476 8.76E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01460 ee3615a7e3533088332c0076faa30b32 479 Gene3D G3DSA:1.20.1250.20 254 477 6.8E-25 T 29-03-2018 CXR48_RS01460 ee3615a7e3533088332c0076faa30b32 479 Gene3D G3DSA:1.20.1250.20 5 196 4.5E-30 T 29-03-2018 CXR48_RS01460 ee3615a7e3533088332c0076faa30b32 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 2.6E-6 T 29-03-2018 CXR48_RS01460 ee3615a7e3533088332c0076faa30b32 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 80 102 2.6E-6 T 29-03-2018 CXR48_RS01460 ee3615a7e3533088332c0076faa30b32 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 2.6E-6 T 29-03-2018 CXR48_RS01460 ee3615a7e3533088332c0076faa30b32 479 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 432 5.3E-92 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CXR48_RS00985 2741e3d36d7f47e45189e80b40334733 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 5.8E-30 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS00985 2741e3d36d7f47e45189e80b40334733 348 Gene3D G3DSA:3.40.50.720 164 281 1.4E-12 T 29-03-2018 CXR48_RS00985 2741e3d36d7f47e45189e80b40334733 348 Pfam PF00107 Zinc-binding dehydrogenase 173 293 2.0E-9 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS00985 2741e3d36d7f47e45189e80b40334733 348 SUPERFAMILY SSF50129 1 172 3.35E-49 T 29-03-2018 IPR011032 GroES-like CXR48_RS00985 2741e3d36d7f47e45189e80b40334733 348 SMART SM00829 7 311 0.0048 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS00985 2741e3d36d7f47e45189e80b40334733 348 Gene3D G3DSA:3.90.180.10 1 163 4.8E-49 T 29-03-2018 CXR48_RS00985 2741e3d36d7f47e45189e80b40334733 348 SUPERFAMILY SSF51735 140 285 7.28E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 SMART SM00421 149 206 1.3E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 SUPERFAMILY SSF52172 1 132 1.2E-30 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 204 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 Pfam PF00072 Response regulator receiver domain 5 116 5.6E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 SUPERFAMILY SSF46894 144 207 1.56E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 Gene3D G3DSA:3.40.50.2300 2 142 3.3E-34 T 29-03-2018 CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 SMART SM00448 3 115 2.8E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS15650 83342f5348f84554482dfca4d08192c0 215 Gene3D G3DSA:1.10.10.10 152 211 4.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15055 abf331ceea2e63850f213245b1f15d07 658 Pfam PF07676 WD40-like Beta Propeller Repeat 231 254 0.05 T 29-03-2018 IPR011659 WD40-like Beta Propeller CXR48_RS15055 abf331ceea2e63850f213245b1f15d07 658 Pfam PF07676 WD40-like Beta Propeller Repeat 182 208 1.1E-4 T 29-03-2018 IPR011659 WD40-like Beta Propeller CXR48_RS15055 abf331ceea2e63850f213245b1f15d07 658 Pfam PF07676 WD40-like Beta Propeller Repeat 66 93 7.0E-9 T 29-03-2018 IPR011659 WD40-like Beta Propeller CXR48_RS15055 abf331ceea2e63850f213245b1f15d07 658 SUPERFAMILY SSF53474 402 658 3.44E-70 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS15055 abf331ceea2e63850f213245b1f15d07 658 Gene3D G3DSA:2.140.10.30 282 402 2.9E-9 T 29-03-2018 CXR48_RS15055 abf331ceea2e63850f213245b1f15d07 658 Gene3D G3DSA:3.40.50.1820 403 658 7.2E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS15055 abf331ceea2e63850f213245b1f15d07 658 Gene3D G3DSA:2.130.10.150 14 281 9.3E-43 T 29-03-2018 CXR48_RS15055 abf331ceea2e63850f213245b1f15d07 658 SUPERFAMILY SSF82171 14 393 6.02E-58 T 29-03-2018 CXR48_RS15055 abf331ceea2e63850f213245b1f15d07 658 Pfam PF00326 Prolyl oligopeptidase family 449 658 1.3E-53 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CXR48_RS12955 9bbf8da4c47c7823c6f05650fe1586fa 663 SMART SM00257 612 656 0.0037 T 29-03-2018 IPR018392 LysM domain CXR48_RS12955 9bbf8da4c47c7823c6f05650fe1586fa 663 Pfam PF01476 LysM domain 614 656 1.2E-4 T 29-03-2018 IPR018392 LysM domain CXR48_RS12955 9bbf8da4c47c7823c6f05650fe1586fa 663 SUPERFAMILY SSF54106 612 656 1.2E-5 T 29-03-2018 IPR018392 LysM domain CXR48_RS12955 9bbf8da4c47c7823c6f05650fe1586fa 663 Gene3D G3DSA:3.10.350.10 608 661 4.0E-7 T 29-03-2018 CXR48_RS05830 06049c8fddce45a44d8345eeda6bbd8c 240 Pfam PF01061 ABC-2 type transporter 7 203 3.0E-23 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CXR48_RS05830 06049c8fddce45a44d8345eeda6bbd8c 240 PIRSF PIRSF006648 2 240 3.2E-20 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 Pfam PF01261 Xylose isomerase-like TIM barrel 162 293 3.0E-8 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 Hamap MF_00455 Xylose isomerase [xylA]. 18 442 56.012 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 11 442 2.6E-223 T 29-03-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 SUPERFAMILY SSF51658 10 444 3.87E-179 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 Gene3D G3DSA:3.20.20.150 9 445 4.5E-113 T 29-03-2018 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 PRINTS PR00688 Xylose isomerase signature 306 317 5.9E-102 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 PRINTS PR00688 Xylose isomerase signature 213 232 5.9E-102 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 PRINTS PR00688 Xylose isomerase signature 98 120 5.9E-102 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 PRINTS PR00688 Xylose isomerase signature 339 350 5.9E-102 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 PRINTS PR00688 Xylose isomerase signature 235 259 5.9E-102 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 PRINTS PR00688 Xylose isomerase signature 139 159 5.9E-102 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 PRINTS PR00688 Xylose isomerase signature 277 304 5.9E-102 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 PRINTS PR00688 Xylose isomerase signature 162 181 5.9E-102 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS08740 ee6dabd83241287037159efa643677c7 445 PRINTS PR00688 Xylose isomerase signature 186 207 5.9E-102 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CXR48_RS18635 bfdfc88092873c936dcaf7e654e86718 139 Gene3D G3DSA:2.40.128.20 35 129 2.5E-51 T 29-03-2018 IPR012674 Calycin CXR48_RS18635 bfdfc88092873c936dcaf7e654e86718 139 Pfam PF11631 Protein of unknown function (DUF3255) 18 139 9.8E-47 T 29-03-2018 IPR021664 Protein of unknown function DUF3255 CXR48_RS18635 bfdfc88092873c936dcaf7e654e86718 139 SUPERFAMILY SSF50814 18 139 8.12E-67 T 29-03-2018 IPR012674 Calycin CXR48_RS12335 76814c420017059fa947a4b08c0ccb9f 280 SUPERFAMILY SSF53223 3 101 4.37E-34 T 29-03-2018 CXR48_RS12335 76814c420017059fa947a4b08c0ccb9f 280 Gene3D G3DSA:3.40.50.720 109 277 7.3E-29 T 29-03-2018 CXR48_RS12335 76814c420017059fa947a4b08c0ccb9f 280 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 8.3E-30 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CXR48_RS12335 76814c420017059fa947a4b08c0ccb9f 280 Gene3D G3DSA:3.40.50.10860 1 108 8.5E-42 T 29-03-2018 CXR48_RS12335 76814c420017059fa947a4b08c0ccb9f 280 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 117 194 5.4E-11 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CXR48_RS12335 76814c420017059fa947a4b08c0ccb9f 280 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 272 34.982 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CXR48_RS12335 76814c420017059fa947a4b08c0ccb9f 280 SUPERFAMILY SSF51735 102 273 6.06E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS12335 76814c420017059fa947a4b08c0ccb9f 280 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 275 5.2E-103 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CXR48_RS07455 ec616b2ec327fb78b5b3f4bf14ffd2a6 346 Pfam PF14504 CAP-associated N-terminal 60 199 2.3E-51 T 29-03-2018 IPR029410 CAP-associated domain CXR48_RS07455 ec616b2ec327fb78b5b3f4bf14ffd2a6 346 Gene3D G3DSA:3.40.33.10 217 343 1.9E-17 T 29-03-2018 IPR014044 CAP domain CXR48_RS07455 ec616b2ec327fb78b5b3f4bf14ffd2a6 346 Gene3D G3DSA:3.30.1450.10 47 116 1.2E-4 T 29-03-2018 CXR48_RS07455 ec616b2ec327fb78b5b3f4bf14ffd2a6 346 Pfam PF00188 Cysteine-rich secretory protein family 230 339 7.8E-16 T 29-03-2018 IPR014044 CAP domain CXR48_RS07455 ec616b2ec327fb78b5b3f4bf14ffd2a6 346 SUPERFAMILY SSF55797 225 342 9.42E-23 T 29-03-2018 IPR014044 CAP domain CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 Gene3D G3DSA:2.10.109.10 88 205 3.5E-26 T 29-03-2018 CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 Hamap MF_00015 LexA repressor [lexA]. 3 205 34.347 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 Pfam PF01726 LexA DNA binding domain 1 65 8.4E-29 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 Pfam PF00717 Peptidase S24-like 123 189 1.7E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 120 130 1.4E-9 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 160 172 1.4E-9 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 131 142 1.4E-9 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 SUPERFAMILY SSF46785 3 70 1.14E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 SUPERFAMILY SSF51306 82 203 3.66E-36 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 TIGRFAM TIGR00498 lexA: repressor LexA 1 205 4.7E-85 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CXR48_RS08865 4094d5eb90e5a9b5bced5c06f5441877 206 Gene3D G3DSA:1.10.10.10 1 70 1.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11575 b34ff3b746cd64493dd9ebaaaf2f2b24 283 Gene3D G3DSA:1.10.1040.10 183 283 3.3E-35 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CXR48_RS11575 b34ff3b746cd64493dd9ebaaaf2f2b24 283 Gene3D G3DSA:3.40.50.720 1 182 2.1E-51 T 29-03-2018 CXR48_RS11575 b34ff3b746cd64493dd9ebaaaf2f2b24 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 185 281 9.2E-35 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CXR48_RS11575 b34ff3b746cd64493dd9ebaaaf2f2b24 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 182 2.1E-62 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CXR48_RS11575 b34ff3b746cd64493dd9ebaaaf2f2b24 283 SUPERFAMILY SSF48179 184 282 1.79E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS11575 b34ff3b746cd64493dd9ebaaaf2f2b24 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 182 206 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CXR48_RS11575 b34ff3b746cd64493dd9ebaaaf2f2b24 283 PIRSF PIRSF000105 1 283 9.5E-90 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CXR48_RS11575 b34ff3b746cd64493dd9ebaaaf2f2b24 283 SUPERFAMILY SSF51735 1 184 3.47E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS04165 11af09e861176c33bf594c1331b91b72 861 Pfam PF09586 Bacterial membrane protein YfhO 13 842 1.6E-182 T 29-03-2018 IPR018580 Uncharacterised protein family YfhO CXR48_RS17915 192b32fc75ef5f3915dc740f7d093a27 247 Gene3D G3DSA:3.90.550.10 2 213 3.9E-16 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS17915 192b32fc75ef5f3915dc740f7d093a27 247 Pfam PF02348 Cytidylyltransferase 7 209 8.2E-38 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CXR48_RS17915 192b32fc75ef5f3915dc740f7d093a27 247 SUPERFAMILY SSF53448 5 211 3.18E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS06945 c22200995f65821b4c6a01203be6d817 164 Gene3D G3DSA:2.40.440.10 55 164 1.8E-32 T 29-03-2018 CXR48_RS06945 c22200995f65821b4c6a01203be6d817 164 SMART SM00257 3 46 2.7E-11 T 29-03-2018 IPR018392 LysM domain CXR48_RS06945 c22200995f65821b4c6a01203be6d817 164 Pfam PF01476 LysM domain 4 46 5.7E-11 T 29-03-2018 IPR018392 LysM domain CXR48_RS06945 c22200995f65821b4c6a01203be6d817 164 Pfam PF03734 L,D-transpeptidase catalytic domain 56 162 6.9E-20 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CXR48_RS06945 c22200995f65821b4c6a01203be6d817 164 SUPERFAMILY SSF54106 2 46 1.57E-10 T 29-03-2018 IPR018392 LysM domain CXR48_RS06945 c22200995f65821b4c6a01203be6d817 164 Gene3D G3DSA:3.10.350.10 2 54 9.9E-14 T 29-03-2018 CXR48_RS06945 c22200995f65821b4c6a01203be6d817 164 SUPERFAMILY SSF141523 55 163 8.76E-34 T 29-03-2018 CXR48_RS11605 f455a7dbeb6f070106b2f303b4c2847e 210 Pfam PF06803 Protein of unknown function (DUF1232) 167 200 1.1E-8 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 CXR48_RS11605 f455a7dbeb6f070106b2f303b4c2847e 210 SMART SM00530 12 67 1.9E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS11605 f455a7dbeb6f070106b2f303b4c2847e 210 Gene3D G3DSA:1.10.3100.10 2 172 5.4E-15 T 29-03-2018 IPR027910 YdiL-like domain CXR48_RS11605 f455a7dbeb6f070106b2f303b4c2847e 210 SUPERFAMILY SSF47413 6 71 1.18E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS11605 f455a7dbeb6f070106b2f303b4c2847e 210 Pfam PF01381 Helix-turn-helix 13 67 3.0E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS02830 1b7e37955681c0313586674646420b04 377 PIRSF PIRSF000112 8 372 4.3E-110 T 29-03-2018 CXR48_RS02830 1b7e37955681c0313586674646420b04 377 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 251 271 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CXR48_RS02830 1b7e37955681c0313586674646420b04 377 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 160 188 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CXR48_RS02830 1b7e37955681c0313586674646420b04 377 Gene3D G3DSA:3.40.50.1970 8 169 2.5E-28 T 29-03-2018 CXR48_RS02830 1b7e37955681c0313586674646420b04 377 Gene3D G3DSA:1.20.1090.10 170 373 1.1E-39 T 29-03-2018 CXR48_RS02830 1b7e37955681c0313586674646420b04 377 Pfam PF00465 Iron-containing alcohol dehydrogenase 18 358 3.0E-59 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CXR48_RS02830 1b7e37955681c0313586674646420b04 377 SUPERFAMILY SSF56796 13 368 1.22E-87 T 29-03-2018 CXR48_RS07955 b14bbe446c90b3c48ad62b7e0a70e9ac 256 Gene3D G3DSA:3.90.1200.10 96 251 2.8E-12 T 29-03-2018 CXR48_RS07955 b14bbe446c90b3c48ad62b7e0a70e9ac 256 Pfam PF01636 Phosphotransferase enzyme family 28 236 1.1E-17 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CXR48_RS07955 b14bbe446c90b3c48ad62b7e0a70e9ac 256 Gene3D G3DSA:3.30.200.20 10 91 4.9E-5 T 29-03-2018 CXR48_RS07955 b14bbe446c90b3c48ad62b7e0a70e9ac 256 SUPERFAMILY SSF56112 23 242 1.73E-26 T 29-03-2018 IPR011009 Protein kinase-like domain CXR48_RS11085 ce25b2044f7fe8fbc40ce2b5045973b5 493 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 28 479 9.2E-153 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS11085 ce25b2044f7fe8fbc40ce2b5045973b5 493 PIRSF PIRSF005690 6 493 3.2E-144 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 SMART SM01004 3 322 6.5E-237 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 321 1.6E-150 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 SUPERFAMILY SSF51569 3 323 2.56E-143 T 29-03-2018 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 Gene3D G3DSA:3.20.20.70 1 324 6.5E-155 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 PIRSF PIRSF001415 1 324 9.3E-154 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 1.5E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 1.5E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 1.5E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 1.5E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 1.5E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS12965 21f130a0d58b22a1c277b2b616cdac89 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 1.5E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CXR48_RS04035 e9251e85324edbfa9fb2f26abf2ba749 315 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 22 306 1.7E-91 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CXR48_RS04035 e9251e85324edbfa9fb2f26abf2ba749 315 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site CXR48_RS04035 e9251e85324edbfa9fb2f26abf2ba749 315 Pfam PF01040 UbiA prenyltransferase family 40 292 4.0E-55 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CXR48_RS04035 e9251e85324edbfa9fb2f26abf2ba749 315 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 20 308 18.171 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CXR48_RS17615 c5e2f6eb3688e9adc1becc07ce67d188 223 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 222 2.7E-112 T 29-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 CXR48_RS17615 c5e2f6eb3688e9adc1becc07ce67d188 223 SUPERFAMILY SSF103501 2 222 6.67E-71 T 29-03-2018 IPR023234 NarG-like domain CXR48_RS17615 c5e2f6eb3688e9adc1becc07ce67d188 223 Pfam PF02665 Nitrate reductase gamma subunit 4 222 1.9E-86 T 29-03-2018 IPR023234 NarG-like domain CXR48_RS17615 c5e2f6eb3688e9adc1becc07ce67d188 223 Gene3D G3DSA:1.20.950.20 1 214 2.8E-48 T 29-03-2018 CXR48_RS17435 ac46c1ad4fbae3b8f6335c43fc6aca0a 127 Pfam PF03899 ATP synthase I chain 10 105 5.8E-20 T 29-03-2018 IPR005598 ATP synthase protein I CXR48_RS17435 ac46c1ad4fbae3b8f6335c43fc6aca0a 127 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 23 127 6.0E-45 T 29-03-2018 CXR48_RS04660 071dfc4426aa41caa79c020daffbce79 80 Pfam PF14148 YhdB-like protein 1 70 9.4E-39 T 29-03-2018 IPR025431 YhdB-like protein CXR48_RS04935 1fa7ba94159f936abef3cd1ea3097d5e 960 Gene3D G3DSA:3.40.50.300 698 958 2.0E-8 T 29-03-2018 CXR48_RS04935 1fa7ba94159f936abef3cd1ea3097d5e 960 Pfam PF13514 AAA domain 1 199 2.7E-26 T 29-03-2018 CXR48_RS04935 1fa7ba94159f936abef3cd1ea3097d5e 960 Gene3D G3DSA:3.40.50.300 1 326 1.3E-15 T 29-03-2018 CXR48_RS04935 1fa7ba94159f936abef3cd1ea3097d5e 960 SUPERFAMILY SSF52540 219 232 1.26E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04935 1fa7ba94159f936abef3cd1ea3097d5e 960 SUPERFAMILY SSF52540 1 160 1.26E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04935 1fa7ba94159f936abef3cd1ea3097d5e 960 SUPERFAMILY SSF52540 853 949 1.26E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01740 51b1013d22be59516f4147d95d3ae790 378 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CXR48_RS01740 51b1013d22be59516f4147d95d3ae790 378 Pfam PF00107 Zinc-binding dehydrogenase 190 257 1.2E-10 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS01740 51b1013d22be59516f4147d95d3ae790 378 Gene3D G3DSA:3.90.180.10 1 179 1.8E-49 T 29-03-2018 CXR48_RS01740 51b1013d22be59516f4147d95d3ae790 378 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 140 2.2E-30 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS01740 51b1013d22be59516f4147d95d3ae790 378 Gene3D G3DSA:3.40.50.720 180 332 7.8E-24 T 29-03-2018 CXR48_RS01740 51b1013d22be59516f4147d95d3ae790 378 Pfam PF13823 Alcohol dehydrogenase GroES-associated 2 23 1.5E-8 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CXR48_RS01740 51b1013d22be59516f4147d95d3ae790 378 SUPERFAMILY SSF50129 2 178 5.69E-60 T 29-03-2018 IPR011032 GroES-like CXR48_RS01740 51b1013d22be59516f4147d95d3ae790 378 SUPERFAMILY SSF51735 157 339 3.25E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS01395 30507d76c5544ee3740665f6993ca26d 312 Gene3D G3DSA:3.10.180.10 147 311 2.5E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS01395 30507d76c5544ee3740665f6993ca26d 312 Gene3D G3DSA:3.10.180.10 2 145 2.1E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS01395 30507d76c5544ee3740665f6993ca26d 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 266 1.2E-36 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS01395 30507d76c5544ee3740665f6993ca26d 312 SUPERFAMILY SSF54593 4 281 6.07E-48 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS02860 91e8fa821f9d2b242f6ee02a9f45c1e2 273 Pfam PF13411 MerR HTH family regulatory protein 9 76 2.2E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS02860 91e8fa821f9d2b242f6ee02a9f45c1e2 273 Gene3D G3DSA:1.10.1660.10 5 65 1.3E-19 T 29-03-2018 CXR48_RS02860 91e8fa821f9d2b242f6ee02a9f45c1e2 273 SUPERFAMILY SSF46955 9 119 2.16E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS02860 91e8fa821f9d2b242f6ee02a9f45c1e2 273 Gene3D G3DSA:3.20.80.10 131 272 4.1E-13 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CXR48_RS02860 91e8fa821f9d2b242f6ee02a9f45c1e2 273 SUPERFAMILY SSF55136 147 270 8.89E-16 T 29-03-2018 CXR48_RS02860 91e8fa821f9d2b242f6ee02a9f45c1e2 273 SMART SM00422 9 78 2.6E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS02860 91e8fa821f9d2b242f6ee02a9f45c1e2 273 Gene3D G3DSA:1.10.1660.10 66 130 6.1E-7 T 29-03-2018 CXR48_RS10020 947f006b4b25b1567d20c5bc0e218593 330 Gene3D G3DSA:1.10.8.60 161 232 2.9E-16 T 29-03-2018 CXR48_RS10020 947f006b4b25b1567d20c5bc0e218593 330 SUPERFAMILY SSF52540 14 227 1.19E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10020 947f006b4b25b1567d20c5bc0e218593 330 SUPERFAMILY SSF46785 253 321 6.74E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS10020 947f006b4b25b1567d20c5bc0e218593 330 Pfam PF00158 Sigma-54 interaction domain 14 152 5.3E-25 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CXR48_RS10020 947f006b4b25b1567d20c5bc0e218593 330 Gene3D G3DSA:3.40.50.300 11 160 3.5E-14 T 29-03-2018 CXR48_RS10020 947f006b4b25b1567d20c5bc0e218593 330 Gene3D G3DSA:1.10.10.10 233 328 3.2E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12405 c2d18fd54ae934647f6171253e116a81 178 Pfam PF13238 AAA domain 5 103 1.2E-8 T 29-03-2018 CXR48_RS12405 c2d18fd54ae934647f6171253e116a81 178 Gene3D G3DSA:3.40.50.300 4 178 7.7E-19 T 29-03-2018 CXR48_RS12405 c2d18fd54ae934647f6171253e116a81 178 SUPERFAMILY SSF52540 134 175 2.94E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS12405 c2d18fd54ae934647f6171253e116a81 178 SUPERFAMILY SSF52540 5 102 2.94E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03635 1d83f75cf4f502f71ef2b8bdc52ae551 140 Gene3D G3DSA:1.10.1660.10 2 59 2.3E-21 T 29-03-2018 CXR48_RS03635 1d83f75cf4f502f71ef2b8bdc52ae551 140 SUPERFAMILY SSF46955 4 120 2.56E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS03635 1d83f75cf4f502f71ef2b8bdc52ae551 140 SMART SM00422 4 74 1.1E-30 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS03635 1d83f75cf4f502f71ef2b8bdc52ae551 140 Gene3D G3DSA:1.10.1660.10 60 140 3.6E-8 T 29-03-2018 CXR48_RS03635 1d83f75cf4f502f71ef2b8bdc52ae551 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 2.7E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS03635 1d83f75cf4f502f71ef2b8bdc52ae551 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 2.7E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS03635 1d83f75cf4f502f71ef2b8bdc52ae551 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 2.7E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS03635 1d83f75cf4f502f71ef2b8bdc52ae551 140 Pfam PF13411 MerR HTH family regulatory protein 4 72 1.5E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS13700 51619e9611ad8e41f446b68fa36cbed2 185 SMART SM00860 41 156 9.2E-11 T 29-03-2018 IPR018958 Knr4/Smi1-like domain CXR48_RS13700 51619e9611ad8e41f446b68fa36cbed2 185 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 41 155 3.5E-14 T 29-03-2018 IPR018958 Knr4/Smi1-like domain CXR48_RS13700 51619e9611ad8e41f446b68fa36cbed2 185 Gene3D G3DSA:3.40.1580.10 22 161 2.3E-20 T 29-03-2018 CXR48_RS13700 51619e9611ad8e41f446b68fa36cbed2 185 SUPERFAMILY SSF160631 35 171 2.62E-25 T 29-03-2018 CXR48_RS02010 0180d368a7dc6eec6e9023c1d7d5c4c7 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 1.8E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS02010 0180d368a7dc6eec6e9023c1d7d5c4c7 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 1.8E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS02010 0180d368a7dc6eec6e9023c1d7d5c4c7 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.8E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS02010 0180d368a7dc6eec6e9023c1d7d5c4c7 104 Gene3D G3DSA:1.10.10.10 4 103 7.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02010 0180d368a7dc6eec6e9023c1d7d5c4c7 104 SMART SM00418 16 94 6.8E-24 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS02010 0180d368a7dc6eec6e9023c1d7d5c4c7 104 Pfam PF01022 Bacterial regulatory protein, arsR family 23 67 4.9E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS02010 0180d368a7dc6eec6e9023c1d7d5c4c7 104 SUPERFAMILY SSF46785 4 94 2.59E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 SUPERFAMILY SSF51338 366 427 2.09E-27 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 SUPERFAMILY SSF51338 1 53 2.09E-27 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 424 47.396 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 Gene3D G3DSA:2.30.40.10 1 58 1.2E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 16 424 1.2E-159 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 Gene3D G3DSA:3.20.20.140 59 413 1.3E-112 T 29-03-2018 CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 Pfam PF01979 Amidohydrolase family 50 419 3.9E-58 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CXR48_RS07720 53b960cf31e23b82625067f4876516e8 428 SUPERFAMILY SSF51556 54 367 1.01E-113 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS06650 3985cd46048e8fe3bc38db10e72c4e73 189 Pfam PF09335 SNARE associated Golgi protein 8 133 7.1E-20 T 29-03-2018 IPR032816 SNARE associated Golgi protein CXR48_RS10585 bb5dd9aafc4214aec527b730dfc8e85f 232 Pfam PF07261 Replication initiation and membrane attachment 131 202 2.8E-24 T 29-03-2018 IPR006343 DnaD domain CXR48_RS10585 bb5dd9aafc4214aec527b730dfc8e85f 232 SUPERFAMILY SSF158499 130 195 1.1E-18 T 29-03-2018 IPR006343 DnaD domain CXR48_RS10585 bb5dd9aafc4214aec527b730dfc8e85f 232 Gene3D G3DSA:1.10.10.630 124 201 4.9E-24 T 29-03-2018 IPR034829 DnaD-like domain CXR48_RS10585 bb5dd9aafc4214aec527b730dfc8e85f 232 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 201 3.1E-25 T 29-03-2018 IPR006343 DnaD domain CXR48_RS02770 5a4e191c0723d34a557279e46c5a6d0e 99 Gene3D G3DSA:1.20.1260.10 1 73 7.7E-12 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS02770 5a4e191c0723d34a557279e46c5a6d0e 99 Pfam PF07875 Coat F domain 15 76 9.8E-25 T 29-03-2018 IPR012851 Spore coat protein CotF-like CXR48_RS05745 d7165e7b3341146a5a11da80b6f34cec 256 Hamap MF_00443 Thiazole synthase [thiG]. 3 256 42.025 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CXR48_RS05745 d7165e7b3341146a5a11da80b6f34cec 256 Gene3D G3DSA:3.20.20.70 1 255 2.0E-53 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS05745 d7165e7b3341146a5a11da80b6f34cec 256 SUPERFAMILY SSF110399 3 241 8.24E-82 T 29-03-2018 CXR48_RS05745 d7165e7b3341146a5a11da80b6f34cec 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 250 2.8E-110 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CXR48_RS16375 ccea763e79f0368af769e927c88e4285 317 Pfam PF01933 Uncharacterised protein family UPF0052 7 292 2.4E-108 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CXR48_RS16375 ccea763e79f0368af769e927c88e4285 317 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 7 315 6.3E-132 T 29-03-2018 IPR010119 Gluconeogenesis factor CXR48_RS16375 ccea763e79f0368af769e927c88e4285 317 Gene3D G3DSA:3.40.50.10680 84 317 1.2E-63 T 29-03-2018 CXR48_RS16375 ccea763e79f0368af769e927c88e4285 317 Hamap MF_00973 Gluconeogenesis factor. 3 317 36.727 T 29-03-2018 IPR010119 Gluconeogenesis factor CXR48_RS16375 ccea763e79f0368af769e927c88e4285 317 SUPERFAMILY SSF142338 4 312 5.23E-109 T 29-03-2018 CXR48_RS06655 b22a197936bf01d63a8b525033f559f7 260 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 243 2.3E-90 T 29-03-2018 IPR022493 Integral membrane YkoY CXR48_RS06655 b22a197936bf01d63a8b525033f559f7 260 Pfam PF03741 Integral membrane protein TerC family 15 203 2.0E-50 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CXR48_RS05475 c39e3d96af221ccb94b61672c16c507d 478 Gene3D G3DSA:3.30.465.10 95 211 5.3E-29 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS05475 c39e3d96af221ccb94b61672c16c507d 478 Pfam PF01565 FAD binding domain 50 181 7.8E-32 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CXR48_RS05475 c39e3d96af221ccb94b61672c16c507d 478 Gene3D G3DSA:3.30.43.10 28 94 2.8E-5 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CXR48_RS05475 c39e3d96af221ccb94b61672c16c507d 478 SUPERFAMILY SSF55103 187 281 2.29E-17 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CXR48_RS05475 c39e3d96af221ccb94b61672c16c507d 478 SUPERFAMILY SSF55103 318 468 2.29E-17 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CXR48_RS05475 c39e3d96af221ccb94b61672c16c507d 478 SUPERFAMILY SSF56176 31 208 5.14E-38 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS09090 62443bcdccf0442830cf63a155209bee 512 SUPERFAMILY SSF75005 36 361 9.71E-53 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS09090 62443bcdccf0442830cf63a155209bee 512 Pfam PF04616 Glycosyl hydrolases family 43 45 359 3.6E-29 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CXR48_RS09090 62443bcdccf0442830cf63a155209bee 512 SMART SM00606 376 511 6.4E-57 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 CXR48_RS09090 62443bcdccf0442830cf63a155209bee 512 Pfam PF03422 Carbohydrate binding module (family 6) 384 511 7.5E-39 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 CXR48_RS09090 62443bcdccf0442830cf63a155209bee 512 Gene3D G3DSA:2.115.10.20 31 373 4.7E-64 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CXR48_RS09090 62443bcdccf0442830cf63a155209bee 512 SUPERFAMILY SSF49785 377 510 2.21E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS09090 62443bcdccf0442830cf63a155209bee 512 Gene3D G3DSA:2.60.120.260 374 512 3.2E-34 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS11490 24fe12c684914598e9894776635b2cc9 219 Gene3D G3DSA:1.10.3720.10 8 218 1.2E-43 T 29-03-2018 CXR48_RS11490 24fe12c684914598e9894776635b2cc9 219 SUPERFAMILY SSF161098 13 207 2.62E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS11490 24fe12c684914598e9894776635b2cc9 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 1.1E-31 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CXR48_RS11490 24fe12c684914598e9894776635b2cc9 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 216 2.6E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS01780 cebbd59bdfebcf0fd666ddd9c03395f3 120 Gene3D G3DSA:1.10.10.10 17 115 3.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01780 cebbd59bdfebcf0fd666ddd9c03395f3 120 Pfam PF01638 HxlR-like helix-turn-helix 19 107 3.1E-39 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CXR48_RS01780 cebbd59bdfebcf0fd666ddd9c03395f3 120 SUPERFAMILY SSF46785 5 106 4.22E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12740 d02dcbf71381377392791cad9754d0d2 165 PIRSF PIRSF005028 1 162 3.5E-55 T 29-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT CXR48_RS12740 d02dcbf71381377392791cad9754d0d2 165 Pfam PF02080 TrkA-C domain 90 159 4.7E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS12740 d02dcbf71381377392791cad9754d0d2 165 SUPERFAMILY SSF116726 84 157 1.57E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS12740 d02dcbf71381377392791cad9754d0d2 165 Gene3D G3DSA:3.30.70.1450 73 160 1.2E-14 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 SUPERFAMILY SSF51126 49 461 2.68E-63 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 SMART SM00710 189 214 4000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 SMART SM00710 216 238 23.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 SMART SM00710 284 305 23.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 SMART SM00710 125 154 9600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 SMART SM00710 249 283 1.8 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 SMART SM00710 312 334 0.18 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 SMART SM00710 156 185 83.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 Pfam PF13229 Right handed beta helix region 149 337 2.7E-12 T 29-03-2018 CXR48_RS16590 ced327ffe8cb4d9d87c7dbaa5942cd4a 468 Gene3D G3DSA:2.160.20.10 21 465 9.2E-55 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS09975 ec1586c255b94e749bfbbe58911fc965 196 SUPERFAMILY SSF51735 2 130 6.27E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS09975 ec1586c255b94e749bfbbe58911fc965 196 Gene3D G3DSA:3.40.50.720 1 193 1.5E-26 T 29-03-2018 CXR48_RS09975 ec1586c255b94e749bfbbe58911fc965 196 Pfam PF02719 Polysaccharide biosynthesis protein 1 152 5.2E-45 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CXR48_RS10315 915c7f78298f2e0e475781426add769e 569 Pfam PF03354 Phage Terminase 81 550 1.9E-93 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CXR48_RS03415 9a85513a4de91dd26542f8ff23b0eb54 303 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 128 6.8E-38 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CXR48_RS03415 9a85513a4de91dd26542f8ff23b0eb54 303 SMART SM00046 3 131 1.1E-8 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CXR48_RS03415 9a85513a4de91dd26542f8ff23b0eb54 303 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 295 7.8E-133 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase CXR48_RS03415 9a85513a4de91dd26542f8ff23b0eb54 303 Gene3D G3DSA:3.40.50.10330 1 132 8.3E-38 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CXR48_RS03415 9a85513a4de91dd26542f8ff23b0eb54 303 SUPERFAMILY SSF111331 1 296 6.28E-87 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CXR48_RS12875 f154704ec8a72c49fe783e0ea090f01c 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS12875 f154704ec8a72c49fe783e0ea090f01c 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.1E-40 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12875 f154704ec8a72c49fe783e0ea090f01c 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 26.814 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12875 f154704ec8a72c49fe783e0ea090f01c 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 9.6E-42 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS12875 f154704ec8a72c49fe783e0ea090f01c 102 SUPERFAMILY SSF141091 1 101 2.62E-38 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS18810 d09a48ee384d992c24b274a8fae47d15 151 Pfam PF06271 RDD family 4 144 2.1E-25 T 29-03-2018 IPR010432 RDD CXR48_RS15145 ef1a5641084a2e1708a518d277d786e2 531 Pfam PF07905 Purine catabolism regulatory protein-like family 5 124 4.0E-32 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain CXR48_RS15145 ef1a5641084a2e1708a518d277d786e2 531 Gene3D G3DSA:1.10.10.60 452 504 1.1E-8 T 29-03-2018 CXR48_RS15145 ef1a5641084a2e1708a518d277d786e2 531 Pfam PF13556 PucR C-terminal helix-turn-helix domain 468 525 6.7E-24 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CXR48_RS19230 5156217643cc5153f825e133b8a65dd3 133 SUPERFAMILY SSF69118 27 129 1.64E-28 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CXR48_RS19230 5156217643cc5153f825e133b8a65dd3 133 Gene3D G3DSA:1.20.1290.10 8 133 1.1E-32 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CXR48_RS19230 5156217643cc5153f825e133b8a65dd3 133 Pfam PF02627 Carboxymuconolactone decarboxylase family 39 122 8.8E-17 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CXR48_RS11075 2b2e199bed291dab605b24078d28eeb4 299 Pfam PF06207 Protein of unknown function (DUF1002) 35 253 2.7E-77 T 29-03-2018 IPR009343 Protein of unknown function DUF1002 CXR48_RS14895 4c048ed1287b829deb5543652e3dcd6c 398 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 111 390 1.1E-86 T 29-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CXR48_RS14895 4c048ed1287b829deb5543652e3dcd6c 398 Pfam PF00425 chorismate binding enzyme 125 383 1.4E-76 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CXR48_RS14895 4c048ed1287b829deb5543652e3dcd6c 398 Gene3D G3DSA:3.60.120.10 2 394 1.0E-99 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CXR48_RS14895 4c048ed1287b829deb5543652e3dcd6c 398 SUPERFAMILY SSF56322 20 393 5.49E-90 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CXR48_RS15295 e72d26a92cebad37ebc728c1e344c9af 271 Pfam PF03180 NLPA lipoprotein 30 269 4.9E-84 T 29-03-2018 IPR004872 Lipoprotein NlpA family CXR48_RS15295 e72d26a92cebad37ebc728c1e344c9af 271 SUPERFAMILY SSF53850 29 269 9.32E-76 T 29-03-2018 CXR48_RS15295 e72d26a92cebad37ebc728c1e344c9af 271 PIRSF PIRSF002854 1 270 3.5E-89 T 29-03-2018 IPR004872 Lipoprotein NlpA family CXR48_RS15295 e72d26a92cebad37ebc728c1e344c9af 271 Gene3D G3DSA:3.40.190.10 124 269 1.2E-43 T 29-03-2018 CXR48_RS15295 e72d26a92cebad37ebc728c1e344c9af 271 Gene3D G3DSA:3.40.190.10 29 123 6.2E-23 T 29-03-2018 CXR48_RS02400 af10cd7d842d610fee2710fecbc74fd2 488 Pfam PF03703 Bacterial PH domain 402 480 2.9E-8 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CXR48_RS02400 af10cd7d842d610fee2710fecbc74fd2 488 Pfam PF03703 Bacterial PH domain 256 330 8.6E-14 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CXR48_RS02400 af10cd7d842d610fee2710fecbc74fd2 488 Pfam PF03703 Bacterial PH domain 67 145 8.3E-18 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CXR48_RS02400 af10cd7d842d610fee2710fecbc74fd2 488 PIRSF PIRSF026631 1 488 2.6E-140 T 29-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CXR48_RS01650 03247a0e182883a057edce8e804c30d4 198 Pfam PF09347 Domain of unknown function (DUF1989) 6 172 8.9E-55 T 29-03-2018 IPR018959 Domain of unknown function DUF1989 CXR48_RS09795 4998cb90fac3f40b9c7c0aa741f6bb1f 231 SMART SM00882 9 205 5.3E-65 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS09795 4998cb90fac3f40b9c7c0aa741f6bb1f 231 Pfam PF01144 Coenzyme A transferase 9 204 2.4E-36 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS09795 4998cb90fac3f40b9c7c0aa741f6bb1f 231 Gene3D G3DSA:3.40.1080.10 6 216 1.8E-59 T 29-03-2018 CXR48_RS09795 4998cb90fac3f40b9c7c0aa741f6bb1f 231 SUPERFAMILY SSF100950 7 212 6.12E-63 T 29-03-2018 CXR48_RS09795 4998cb90fac3f40b9c7c0aa741f6bb1f 231 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 7 211 1.8E-89 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 Gene3D G3DSA:3.50.50.60 1 129 5.0E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 Gene3D G3DSA:3.50.50.60 130 238 3.3E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 294 3.9E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 SUPERFAMILY SSF51905 4 302 6.2E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 305 3.4E-122 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.0E-37 T 29-03-2018 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 7.0E-37 T 29-03-2018 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 7.0E-37 T 29-03-2018 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 7.0E-37 T 29-03-2018 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 7.0E-37 T 29-03-2018 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 7.2E-72 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 7.2E-72 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 7.2E-72 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 7.2E-72 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 7.2E-72 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 7.2E-72 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 7.2E-72 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 7.2E-72 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 7.2E-72 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS16390 0016629ba6469c3b022d90ad4da08a19 316 Gene3D G3DSA:3.50.50.60 239 315 2.2E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS02600 de11749f984ee7939157b23803602585 108 Gene3D G3DSA:3.40.250.10 10 108 8.7E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02600 de11749f984ee7939157b23803602585 108 SMART SM00450 18 108 2.2E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02600 de11749f984ee7939157b23803602585 108 Pfam PF00581 Rhodanese-like domain 20 108 1.0E-14 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02600 de11749f984ee7939157b23803602585 108 SUPERFAMILY SSF52821 3 107 6.68E-30 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS02040 3920618ac3568aabaa3bfad1f11d0410 203 Gene3D G3DSA:2.60.40.10 21 170 4.3E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS02040 3920618ac3568aabaa3bfad1f11d0410 203 Pfam PF07987 Domain of unkown function (DUF1775) 27 145 2.7E-18 T 29-03-2018 IPR012533 YcnI-like CXR48_RS16130 ebe00c261cf355ec9a15f3b00b0cb605 72 Pfam PF09628 YvfG protein 3 69 9.9E-38 T 29-03-2018 IPR018590 Uncharacterised domain YvfG CXR48_RS16130 ebe00c261cf355ec9a15f3b00b0cb605 72 SUPERFAMILY SSF158388 3 69 1.24E-33 T 29-03-2018 CXR48_RS17500 a99e5ffef6ec83c3482168d6202de2c3 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CXR48_RS17500 a99e5ffef6ec83c3482168d6202de2c3 356 Gene3D G3DSA:1.20.58.410 1 100 2.0E-19 T 29-03-2018 CXR48_RS17500 a99e5ffef6ec83c3482168d6202de2c3 356 Pfam PF03462 PCRF domain 8 202 5.6E-74 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CXR48_RS17500 a99e5ffef6ec83c3482168d6202de2c3 356 SMART SM00937 63 177 1.8E-62 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CXR48_RS17500 a99e5ffef6ec83c3482168d6202de2c3 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.639 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CXR48_RS17500 a99e5ffef6ec83c3482168d6202de2c3 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 354 4.7E-173 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CXR48_RS17500 a99e5ffef6ec83c3482168d6202de2c3 356 Pfam PF00472 RF-1 domain 210 319 1.0E-40 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CXR48_RS17500 a99e5ffef6ec83c3482168d6202de2c3 356 SUPERFAMILY SSF75620 8 351 2.09E-133 T 29-03-2018 CXR48_RS17500 a99e5ffef6ec83c3482168d6202de2c3 356 Gene3D G3DSA:3.30.160.20 207 291 5.4E-31 T 29-03-2018 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 Gene3D G3DSA:3.40.50.1370 152 322 4.2E-61 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 Gene3D G3DSA:3.40.50.1370 1 151 8.1E-59 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 16 152 1.1E-51 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 15 315 80.893 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 2.3E-28 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 2.3E-28 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 2.3E-28 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 279 302 2.3E-28 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 312 5.0E-59 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 16 314 6.1E-128 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 293 304 1.5E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 55 69 1.5E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 231 241 1.5E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 88 101 1.5E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 128 142 1.5E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CXR48_RS05515 302e0afb46f2a6fa13071be309d44c31 323 SUPERFAMILY SSF53671 11 315 9.95E-111 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CXR48_RS16080 949786fdba8eaf48b31d73556f2b3a3a 285 Pfam PF01380 SIS domain 130 258 3.5E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CXR48_RS16080 949786fdba8eaf48b31d73556f2b3a3a 285 Gene3D G3DSA:3.40.50.10490 99 284 8.0E-43 T 29-03-2018 CXR48_RS16080 949786fdba8eaf48b31d73556f2b3a3a 285 SUPERFAMILY SSF53697 99 282 5.11E-48 T 29-03-2018 CXR48_RS16080 949786fdba8eaf48b31d73556f2b3a3a 285 Gene3D G3DSA:1.10.10.10 5 98 8.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16080 949786fdba8eaf48b31d73556f2b3a3a 285 SUPERFAMILY SSF46689 9 82 2.15E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS16080 949786fdba8eaf48b31d73556f2b3a3a 285 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 81 1.0E-19 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CXR48_RS15625 aeb1289f9b5f421d71ceee16294952c2 160 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 151 9.8E-33 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CXR48_RS15625 aeb1289f9b5f421d71ceee16294952c2 160 PIRSF PIRSF030780 1 158 4.0E-21 T 29-03-2018 IPR016956 Inner membrane protein YdjM CXR48_RS04825 9676fd6bbe9adaa90cfd6243eef7f17e 585 SUPERFAMILY SSF90123 6 325 1.57E-71 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04825 9676fd6bbe9adaa90cfd6243eef7f17e 585 Gene3D G3DSA:1.20.1560.10 3 325 4.0E-58 T 29-03-2018 CXR48_RS04825 9676fd6bbe9adaa90cfd6243eef7f17e 585 Gene3D G3DSA:3.40.50.300 326 578 4.0E-73 T 29-03-2018 CXR48_RS04825 9676fd6bbe9adaa90cfd6243eef7f17e 585 Pfam PF00005 ABC transporter 355 501 1.0E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS04825 9676fd6bbe9adaa90cfd6243eef7f17e 585 Pfam PF00664 ABC transporter transmembrane region 21 292 5.3E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS04825 9676fd6bbe9adaa90cfd6243eef7f17e 585 SMART SM00382 363 549 8.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04825 9676fd6bbe9adaa90cfd6243eef7f17e 585 SUPERFAMILY SSF52540 333 574 3.07E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04825 9676fd6bbe9adaa90cfd6243eef7f17e 585 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS01310 f1c72e42fb91c3eb84e0a6ce6166461e 177 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 45 67 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CXR48_RS01310 f1c72e42fb91c3eb84e0a6ce6166461e 177 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 9 161 1.3E-60 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CXR48_RS01310 f1c72e42fb91c3eb84e0a6ce6166461e 177 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 67 1.4E-13 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CXR48_RS13670 ff1717ac5e303e0ab15b2a7f93ed06c0 160 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 29-03-2018 IPR000614 Free Met sulfoxide reductase conserved site CXR48_RS13670 ff1717ac5e303e0ab15b2a7f93ed06c0 160 SUPERFAMILY SSF55781 8 155 9.38E-42 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS13670 ff1717ac5e303e0ab15b2a7f93ed06c0 160 Pfam PF13185 GAF domain 53 154 4.3E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 CXR48_RS13670 ff1717ac5e303e0ab15b2a7f93ed06c0 160 Gene3D G3DSA:3.30.450.40 7 157 4.5E-23 T 29-03-2018 IPR029016 GAF domain-like CXR48_RS05480 ea09d3c572cab6bee42e8ac1d085a174 180 Pfam PF07690 Major Facilitator Superfamily 10 174 2.6E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS05480 ea09d3c572cab6bee42e8ac1d085a174 180 SUPERFAMILY SSF103473 6 176 1.28E-23 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS05480 ea09d3c572cab6bee42e8ac1d085a174 180 Gene3D G3DSA:1.20.1250.20 2 179 2.7E-21 T 29-03-2018 CXR48_RS17365 37054c8bc74a02e17e4caab4f20cdab1 228 Pfam PF00092 von Willebrand factor type A domain 37 219 5.0E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS17365 37054c8bc74a02e17e4caab4f20cdab1 228 SMART SM00327 35 227 2.1E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS17365 37054c8bc74a02e17e4caab4f20cdab1 228 Gene3D G3DSA:3.40.50.410 34 227 1.6E-30 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS17365 37054c8bc74a02e17e4caab4f20cdab1 228 SUPERFAMILY SSF53300 34 220 6.23E-26 T 29-03-2018 IPR002035 von Willebrand factor, type A CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 Pfam PF01189 16S rRNA methyltransferase RsmB/F 245 443 1.4E-58 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 7 447 1.6E-191 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 Gene3D G3DSA:1.10.940.10 1 143 1.1E-33 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 256 266 4.3E-30 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 428 445 4.3E-30 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 241 4.3E-30 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 374 390 4.3E-30 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 324 336 4.3E-30 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 Pfam PF01029 NusB family 5 128 2.1E-32 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 323 334 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 SUPERFAMILY SSF53335 138 446 8.52E-78 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 Gene3D G3DSA:3.40.50.150 236 447 1.1E-60 T 29-03-2018 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 SUPERFAMILY SSF48013 5 154 2.49E-37 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CXR48_RS07845 b85d8a94eb8c446ea255150f5d515e5c 447 Gene3D G3DSA:3.30.70.1170 180 235 1.4E-10 T 29-03-2018 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 Gene3D G3DSA:3.60.21.10 1 286 7.7E-53 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 SUPERFAMILY SSF56300 4 277 7.59E-68 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 Pfam PF02872 5'-nucleotidase, C-terminal domain 290 428 1.2E-13 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 SUPERFAMILY SSF55816 289 462 6.93E-26 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 PIRSF PIRSF036361 1 464 3.1E-183 T 29-03-2018 IPR011240 Phosphoesterase-related protein YunD CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 Gene3D G3DSA:3.90.780.10 287 464 5.1E-29 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 PRINTS PR01607 Apyrase family signature 188 211 9.5E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 PRINTS PR01607 Apyrase family signature 3 21 9.5E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 PRINTS PR01607 Apyrase family signature 414 433 9.5E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 PRINTS PR01607 Apyrase family signature 216 236 9.5E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 PRINTS PR01607 Apyrase family signature 169 186 9.5E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 PRINTS PR01607 Apyrase family signature 330 353 9.5E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CXR48_RS15120 c3c8f5030468926503af9bbb0575784c 464 Pfam PF00149 Calcineurin-like phosphoesterase 5 205 4.8E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CXR48_RS11470 a79d03653c0b1bb5157661b349d689e1 142 SUPERFAMILY SSF54593 2 133 9.35E-32 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS11470 a79d03653c0b1bb5157661b349d689e1 142 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 115 2.0E-24 T 29-03-2018 CXR48_RS11470 a79d03653c0b1bb5157661b349d689e1 142 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 3 130 2.3E-41 T 29-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 CXR48_RS11470 a79d03653c0b1bb5157661b349d689e1 142 Gene3D G3DSA:3.10.180.10 1 131 2.0E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS11470 a79d03653c0b1bb5157661b349d689e1 142 ProSitePatterns PS00934 Glyoxalase I signature 1. 6 27 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CXR48_RS16555 60a0a95eb99f7558c24967694f41132e 833 SUPERFAMILY SSF56059 14 296 9.65E-75 T 29-03-2018 CXR48_RS16555 60a0a95eb99f7558c24967694f41132e 833 Gene3D G3DSA:3.50.30.10 726 832 2.8E-33 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS16555 60a0a95eb99f7558c24967694f41132e 833 Gene3D G3DSA:3.30.470.20 164 313 2.6E-39 T 29-03-2018 CXR48_RS16555 60a0a95eb99f7558c24967694f41132e 833 Gene3D G3DSA:3.30.1490.20 4 163 9.3E-37 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CXR48_RS16555 60a0a95eb99f7558c24967694f41132e 833 Pfam PF00391 PEP-utilising enzyme, mobile domain 752 823 2.3E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS16555 60a0a95eb99f7558c24967694f41132e 833 SUPERFAMILY SSF52009 724 826 1.57E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CXR48_RS16555 60a0a95eb99f7558c24967694f41132e 833 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 15 302 9.5E-80 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CXR48_RS04230 fe3b5e84ef4c6c1aa8c582f6b4da9f5c 117 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 1 113 7.0E-56 T 29-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 CXR48_RS04230 fe3b5e84ef4c6c1aa8c582f6b4da9f5c 117 Pfam PF11023 Zinc-ribbon containing domain 3 113 5.2E-59 T 29-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 CXR48_RS04230 fe3b5e84ef4c6c1aa8c582f6b4da9f5c 117 Hamap MF_01502 UPF0295 protein . 1 115 36.607 T 29-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 CXR48_RS02865 241b4f90a6a11a58bf498cfc71d0b7d3 290 Pfam PF00892 EamA-like transporter family 6 139 2.8E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS02865 241b4f90a6a11a58bf498cfc71d0b7d3 290 Pfam PF00892 EamA-like transporter family 150 287 3.1E-25 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS02865 241b4f90a6a11a58bf498cfc71d0b7d3 290 SUPERFAMILY SSF103481 43 142 7.85E-14 T 29-03-2018 CXR48_RS02865 241b4f90a6a11a58bf498cfc71d0b7d3 290 SUPERFAMILY SSF103481 188 287 1.83E-16 T 29-03-2018 CXR48_RS10840 a742f37bc12dd836a4d729e16640fc96 200 PIRSF PIRSF036710 1 200 1.6E-65 T 29-03-2018 IPR014617 Predicted membrane protein, Bacillus YphA type CXR48_RS08000 b78815e9228473ee4893d7a3a0b3ee0b 282 Gene3D G3DSA:3.40.50.300 12 179 9.5E-32 T 29-03-2018 CXR48_RS08000 b78815e9228473ee4893d7a3a0b3ee0b 282 Pfam PF01926 50S ribosome-binding GTPase 123 213 9.9E-17 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS08000 b78815e9228473ee4893d7a3a0b3ee0b 282 Gene3D G3DSA:1.10.1580.10 180 272 1.6E-23 T 29-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CXR48_RS08000 b78815e9228473ee4893d7a3a0b3ee0b 282 SUPERFAMILY SSF52540 9 190 3.97E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08000 b78815e9228473ee4893d7a3a0b3ee0b 282 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 3.8E-115 T 29-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CXR48_RS08000 b78815e9228473ee4893d7a3a0b3ee0b 282 PIRSF PIRSF006230 1 282 1.5E-104 T 29-03-2018 IPR016478 GTPase, MTG1 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 SUPERFAMILY SSF53067 144 329 1.74E-48 T 29-03-2018 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 Gene3D G3DSA:3.30.420.40 156 191 0.001 T 29-03-2018 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 4 331 5.3E-136 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 SUPERFAMILY SSF53067 5 141 9.08E-38 T 29-03-2018 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 Gene3D G3DSA:3.90.640.10 192 247 2.3E-30 T 29-03-2018 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 Pfam PF06723 MreB/Mbl protein 5 331 1.8E-143 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 Gene3D G3DSA:3.30.420.40 2 155 3.2E-38 T 29-03-2018 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 Gene3D G3DSA:3.30.420.40 248 312 7.1E-8 T 29-03-2018 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 1.8E-53 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 1.8E-53 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 1.8E-53 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 1.8E-53 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS07145 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 1.8E-53 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CXR48_RS02825 c68f95799f2838a593195f0c547a7001 285 PIRSF PIRSF006483 1 277 7.0E-74 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS02825 c68f95799f2838a593195f0c547a7001 285 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 211 2.5E-56 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS02825 c68f95799f2838a593195f0c547a7001 285 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 218 270 9.3E-18 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CXR48_RS13890 83406fcf6794f87bbf617305df526f7f 308 PIRSF PIRSF012560 1 308 4.7E-120 T 29-03-2018 IPR012397 Pullulan 6-glucanohydrolase CXR48_RS18265 beb5dcb267e5e354f2ea31b185ff1a73 110 SUPERFAMILY SSF46973 2 101 2.09E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS18265 beb5dcb267e5e354f2ea31b185ff1a73 110 PIRSF PIRSF000699 1 105 2.7E-38 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS18265 beb5dcb267e5e354f2ea31b185ff1a73 110 TIGRFAM TIGR00823 EIIA-LAC: PTS system, lactose-specific IIa component 3 101 2.2E-41 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS18265 beb5dcb267e5e354f2ea31b185ff1a73 110 Gene3D G3DSA:1.20.58.80 3 101 5.8E-38 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS18265 beb5dcb267e5e354f2ea31b185ff1a73 110 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 100 8.6E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 215 1.8E-95 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 Pfam PF01470 Pyroglutamyl peptidase 3 201 4.1E-86 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 3 199 42.939 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 PIRSF PIRSF015592 2 213 5.6E-86 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 SUPERFAMILY SSF53182 2 207 9.16E-72 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 70 86 - T 29-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 163 175 1.2E-51 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 63 75 1.2E-51 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 81 101 1.2E-51 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 133 149 1.2E-51 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 5 28 1.2E-51 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 Gene3D G3DSA:3.40.630.20 1 215 4.4E-65 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CXR48_RS01450 7fb4e57e27e9c54fb953a8b6a7801ddf 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 131 145 - T 29-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CXR48_RS17600 8a55aa22b6bcc8371981724ba5be3942 575 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS17600 8a55aa22b6bcc8371981724ba5be3942 575 Gene3D G3DSA:1.20.1560.10 1 316 5.0E-64 T 29-03-2018 CXR48_RS17600 8a55aa22b6bcc8371981724ba5be3942 575 Pfam PF00664 ABC transporter transmembrane region 17 286 2.3E-62 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS17600 8a55aa22b6bcc8371981724ba5be3942 575 SMART SM00382 358 544 1.9E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS17600 8a55aa22b6bcc8371981724ba5be3942 575 SUPERFAMILY SSF52540 323 569 1.11E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS17600 8a55aa22b6bcc8371981724ba5be3942 575 SUPERFAMILY SSF90123 3 319 1.31E-77 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CXR48_RS17600 8a55aa22b6bcc8371981724ba5be3942 575 Pfam PF00005 ABC transporter 349 498 2.6E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS17600 8a55aa22b6bcc8371981724ba5be3942 575 Gene3D G3DSA:3.40.50.300 317 572 6.6E-76 T 29-03-2018 CXR48_RS04400 c2adaf7555a2d34883aec3869ae00d3e 329 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 33 320 1.2E-105 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CXR48_RS04400 c2adaf7555a2d34883aec3869ae00d3e 329 Pfam PF09084 NMT1/THI5 like 42 254 5.7E-24 T 29-03-2018 IPR015168 SsuA/THI5-like CXR48_RS04400 c2adaf7555a2d34883aec3869ae00d3e 329 Gene3D G3DSA:3.40.190.10 135 323 3.5E-40 T 29-03-2018 CXR48_RS04400 c2adaf7555a2d34883aec3869ae00d3e 329 Gene3D G3DSA:3.40.190.10 28 134 3.2E-15 T 29-03-2018 CXR48_RS04400 c2adaf7555a2d34883aec3869ae00d3e 329 SMART SM00062 32 267 2.1E-33 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS04400 c2adaf7555a2d34883aec3869ae00d3e 329 SUPERFAMILY SSF53850 31 255 5.29E-48 T 29-03-2018 CXR48_RS17910 5d9c0ab6525dec387fda445af5e2b1ee 334 Gene3D G3DSA:3.40.50.2000 150 317 1.9E-18 T 29-03-2018 CXR48_RS17910 5d9c0ab6525dec387fda445af5e2b1ee 334 SUPERFAMILY SSF53756 149 333 2.72E-13 T 29-03-2018 CXR48_RS17910 5d9c0ab6525dec387fda445af5e2b1ee 334 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 167 283 1.4E-4 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CXR48_RS14270 0ff6ca083ead2a1d4bd884344e939ae5 156 PIRSF PIRSF005859 1 156 7.6E-36 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CXR48_RS14270 0ff6ca083ead2a1d4bd884344e939ae5 156 Pfam PF03073 TspO/MBR family 12 152 3.3E-27 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CXR48_RS14190 f0ffaa3e5da91040bf86f43ea41227a1 147 Pfam PF13115 YtkA-like 31 112 7.2E-13 T 29-03-2018 IPR032693 YtkA-like domain CXR48_RS14190 f0ffaa3e5da91040bf86f43ea41227a1 147 Gene3D G3DSA:2.60.40.10 25 131 2.5E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS09155 9978ae1a5dbe933646ef29de0c7d3669 386 Pfam PF00155 Aminotransferase class I and II 40 374 9.0E-63 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS09155 9978ae1a5dbe933646ef29de0c7d3669 386 SUPERFAMILY SSF53383 9 383 1.04E-102 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS09155 9978ae1a5dbe933646ef29de0c7d3669 386 Gene3D G3DSA:3.90.1150.10 277 386 4.7E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS09155 9978ae1a5dbe933646ef29de0c7d3669 386 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 230 239 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CXR48_RS09155 9978ae1a5dbe933646ef29de0c7d3669 386 Gene3D G3DSA:3.40.640.10 46 276 4.8E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS09155 9978ae1a5dbe933646ef29de0c7d3669 386 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 24 375 1.4E-142 T 29-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 CXR48_RS15870 76f875bf0eacbd3c40966d44a0adcd9a 220 SMART SM00862 145 219 1.6E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS15870 76f875bf0eacbd3c40966d44a0adcd9a 220 Pfam PF00072 Response regulator receiver domain 4 112 3.5E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS15870 76f875bf0eacbd3c40966d44a0adcd9a 220 Gene3D G3DSA:1.10.10.10 121 220 5.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15870 76f875bf0eacbd3c40966d44a0adcd9a 220 SUPERFAMILY SSF52172 3 178 1.42E-34 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS15870 76f875bf0eacbd3c40966d44a0adcd9a 220 Gene3D G3DSA:3.40.50.2300 1 120 2.0E-31 T 29-03-2018 CXR48_RS15870 76f875bf0eacbd3c40966d44a0adcd9a 220 SMART SM00448 2 111 4.5E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS15870 76f875bf0eacbd3c40966d44a0adcd9a 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 7.7E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS07170 b79991869f84286160399b5bcd739c71 221 Pfam PF02254 TrkA-N domain 5 120 3.3E-29 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CXR48_RS07170 b79991869f84286160399b5bcd739c71 221 Pfam PF02080 TrkA-C domain 149 216 4.5E-15 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS07170 b79991869f84286160399b5bcd739c71 221 SUPERFAMILY SSF116726 131 215 4.05E-21 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS07170 b79991869f84286160399b5bcd739c71 221 SUPERFAMILY SSF51735 4 134 1.34E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS07170 b79991869f84286160399b5bcd739c71 221 Gene3D G3DSA:3.30.70.1450 136 218 1.2E-21 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CXR48_RS07170 b79991869f84286160399b5bcd739c71 221 Gene3D G3DSA:3.40.50.720 3 135 2.4E-24 T 29-03-2018 CXR48_RS14755 1e882b928a94bf20e4d8895e9262cb73 763 SUPERFAMILY SSF50156 26 103 1.17E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS14755 1e882b928a94bf20e4d8895e9262cb73 763 Gene3D G3DSA:3.30.565.10 517 761 4.1E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14755 1e882b928a94bf20e4d8895e9262cb73 763 SMART SM00387 670 763 8.6E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14755 1e882b928a94bf20e4d8895e9262cb73 763 SUPERFAMILY SSF55874 637 758 4.06E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14755 1e882b928a94bf20e4d8895e9262cb73 763 Gene3D G3DSA:2.30.42.10 22 112 1.8E-6 T 29-03-2018 CXR48_RS14755 1e882b928a94bf20e4d8895e9262cb73 763 SMART SM00228 31 97 0.004 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS14755 1e882b928a94bf20e4d8895e9262cb73 763 Pfam PF07730 Histidine kinase 563 632 4.3E-13 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CXR48_RS15290 e76304a3f680b06817675063e9dfadc6 128 SUPERFAMILY SSF69118 20 126 8.64E-25 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CXR48_RS15290 e76304a3f680b06817675063e9dfadc6 128 Gene3D G3DSA:1.20.1290.10 3 128 2.2E-20 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CXR48_RS15290 e76304a3f680b06817675063e9dfadc6 128 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 116 4.3E-17 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CXR48_RS15660 3b531f6fc5ba4ef79202e6a0b9065a75 311 Gene3D G3DSA:3.40.50.300 1 274 1.2E-66 T 29-03-2018 CXR48_RS15660 3b531f6fc5ba4ef79202e6a0b9065a75 311 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15660 3b531f6fc5ba4ef79202e6a0b9065a75 311 Pfam PF00005 ABC transporter 20 162 1.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15660 3b531f6fc5ba4ef79202e6a0b9065a75 311 SMART SM00382 28 217 1.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15660 3b531f6fc5ba4ef79202e6a0b9065a75 311 SUPERFAMILY SSF52540 3 222 1.74E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14395 0ed24bf4e768791909c3f5bce374377d 193 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 8 188 3.6E-61 T 29-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CXR48_RS14395 0ed24bf4e768791909c3f5bce374377d 193 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 10 187 3.3E-57 T 29-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CXR48_RS11465 2083420225ddd7dd128e7d7070a62009 505 Pfam PF01039 Carboxyl transferase domain 26 503 2.8E-181 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CXR48_RS11465 2083420225ddd7dd128e7d7070a62009 505 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 123 141 5.3E-7 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS11465 2083420225ddd7dd128e7d7070a62009 505 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 89 103 5.3E-7 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS11465 2083420225ddd7dd128e7d7070a62009 505 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 188 199 5.3E-7 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS11465 2083420225ddd7dd128e7d7070a62009 505 SUPERFAMILY SSF52096 238 505 4.23E-80 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS11465 2083420225ddd7dd128e7d7070a62009 505 Gene3D G3DSA:3.90.226.10 251 505 4.5E-66 T 29-03-2018 CXR48_RS11465 2083420225ddd7dd128e7d7070a62009 505 SUPERFAMILY SSF52096 5 244 7.24E-77 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS11465 2083420225ddd7dd128e7d7070a62009 505 Gene3D G3DSA:3.90.226.10 1 250 1.3E-73 T 29-03-2018 CXR48_RS09080 ccafa2d53c8ec25bbb3562fb6dae51cc 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 2.1E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS09080 ccafa2d53c8ec25bbb3562fb6dae51cc 235 SUPERFAMILY SSF52172 7 187 9.48E-37 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS09080 ccafa2d53c8ec25bbb3562fb6dae51cc 235 Pfam PF00072 Response regulator receiver domain 8 117 1.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS09080 ccafa2d53c8ec25bbb3562fb6dae51cc 235 Gene3D G3DSA:1.10.10.10 131 235 1.5E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09080 ccafa2d53c8ec25bbb3562fb6dae51cc 235 SMART SM00862 154 230 1.1E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS09080 ccafa2d53c8ec25bbb3562fb6dae51cc 235 Gene3D G3DSA:3.40.50.2300 5 130 2.8E-32 T 29-03-2018 CXR48_RS09080 ccafa2d53c8ec25bbb3562fb6dae51cc 235 SMART SM00448 6 117 1.7E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 64 1.1E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 SMART SM00345 5 64 4.7E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 Gene3D G3DSA:1.10.10.10 1 74 3.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 SUPERFAMILY SSF48008 85 222 5.75E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 2.0E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 2.0E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 SUPERFAMILY SSF46785 1 68 6.12E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 SMART SM00895 89 216 1.9E-24 T 29-03-2018 IPR011711 GntR, C-terminal CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 Pfam PF07729 FCD domain 89 215 7.5E-27 T 29-03-2018 IPR011711 GntR, C-terminal CXR48_RS16115 f3987bc6d70fb781c49715e26020f0a9 229 Gene3D G3DSA:1.20.120.530 75 228 2.5E-32 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CXR48_RS06475 2268fa27ead258179e298b13e432a110 286 Gene3D G3DSA:3.75.10.10 16 285 2.9E-64 T 29-03-2018 CXR48_RS06475 2268fa27ead258179e298b13e432a110 286 SUPERFAMILY SSF55909 9 285 6.78E-74 T 29-03-2018 CXR48_RS06475 2268fa27ead258179e298b13e432a110 286 Pfam PF02274 Amidinotransferase 26 284 9.1E-47 T 29-03-2018 CXR48_RS05440 eec60a6a6ec88a1e485d7a800dd4c12d 280 PIRSF PIRSF006483 1 280 2.4E-98 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS05440 eec60a6a6ec88a1e485d7a800dd4c12d 280 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 221 275 2.7E-19 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CXR48_RS05440 eec60a6a6ec88a1e485d7a800dd4c12d 280 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 215 6.5E-60 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS12440 43d97fdcaaf3984ab09632db07c99aa0 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 259 1.5E-58 T 29-03-2018 IPR000150 Cof family GO:0016787 CXR48_RS12440 43d97fdcaaf3984ab09632db07c99aa0 270 SUPERFAMILY SSF56784 1 263 1.99E-67 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12440 43d97fdcaaf3984ab09632db07c99aa0 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 3.7E-59 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12440 43d97fdcaaf3984ab09632db07c99aa0 270 Gene3D G3DSA:3.40.50.1000 3 96 3.9E-11 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12440 43d97fdcaaf3984ab09632db07c99aa0 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 232 3.9E-21 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CXR48_RS12440 43d97fdcaaf3984ab09632db07c99aa0 270 Gene3D G3DSA:3.30.1240.10 97 189 1.2E-25 T 29-03-2018 CXR48_RS11505 e1bccb5f4213cd024717b599c0562e4f 298 SUPERFAMILY SSF111331 4 296 3.27E-74 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CXR48_RS11505 e1bccb5f4213cd024717b599c0562e4f 298 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 127 4.2E-32 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CXR48_RS11505 e1bccb5f4213cd024717b599c0562e4f 298 Gene3D G3DSA:3.40.50.10330 1 132 6.0E-29 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CXR48_RS11505 e1bccb5f4213cd024717b599c0562e4f 298 SMART SM00046 5 131 3.1E-20 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CXR48_RS11505 e1bccb5f4213cd024717b599c0562e4f 298 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 294 1.1E-105 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 213 276 1.8E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 Gene3D G3DSA:3.30.565.10 278 427 1.9E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 SMART SM00388 211 278 2.2E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 Gene3D G3DSA:1.10.287.130 199 274 1.2E-11 T 29-03-2018 CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 424 3.9E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 SUPERFAMILY SSF55874 269 424 2.88E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 SUPERFAMILY SSF47384 206 276 7.26E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 SMART SM00387 319 426 9.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 3.6E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 3.6E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS14640 7a60cfd78e80bd94c2d4ccd0228c8d04 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 3.6E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS04085 86ee10e58fb01f30d1c358bdabd2d7ca 294 Pfam PF02567 Phenazine biosynthesis-like protein 9 286 7.9E-82 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CXR48_RS04085 86ee10e58fb01f30d1c358bdabd2d7ca 294 SUPERFAMILY SSF54506 6 286 7.71E-62 T 29-03-2018 CXR48_RS04085 86ee10e58fb01f30d1c358bdabd2d7ca 294 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 288 7.4E-104 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CXR48_RS04085 86ee10e58fb01f30d1c358bdabd2d7ca 294 Gene3D G3DSA:3.10.310.10 1 125 1.0E-30 T 29-03-2018 CXR48_RS04085 86ee10e58fb01f30d1c358bdabd2d7ca 294 PIRSF PIRSF016184 1 293 1.5E-74 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CXR48_RS04085 86ee10e58fb01f30d1c358bdabd2d7ca 294 Gene3D G3DSA:3.10.310.10 126 282 1.4E-32 T 29-03-2018 CXR48_RS08075 1f3342e964786ec68e00f5e26df11f2a 106 Pfam PF02049 Flagellar hook-basal body complex protein FliE 21 106 2.3E-28 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CXR48_RS08075 1f3342e964786ec68e00f5e26df11f2a 106 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 36 52 1.4E-18 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CXR48_RS08075 1f3342e964786ec68e00f5e26df11f2a 106 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 91 104 1.4E-18 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CXR48_RS08075 1f3342e964786ec68e00f5e26df11f2a 106 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 70 86 1.4E-18 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CXR48_RS08075 1f3342e964786ec68e00f5e26df11f2a 106 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 3 106 2.7E-38 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CXR48_RS08075 1f3342e964786ec68e00f5e26df11f2a 106 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 106 18.999 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CXR48_RS13885 49984ac94d1ccd9f506aca1da14db19c 309 SUPERFAMILY SSF111331 2 299 5.45E-62 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CXR48_RS13885 49984ac94d1ccd9f506aca1da14db19c 309 SMART SM00046 3 125 6.5E-4 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CXR48_RS13885 49984ac94d1ccd9f506aca1da14db19c 309 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 309 1.5E-91 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase CXR48_RS13885 49984ac94d1ccd9f506aca1da14db19c 309 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 124 2.7E-28 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CXR48_RS13885 49984ac94d1ccd9f506aca1da14db19c 309 Gene3D G3DSA:3.40.50.10330 1 124 9.9E-28 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CXR48_RS06485 ca285c089734a462b96f6aa74f6961a6 181 Pfam PF13302 Acetyltransferase (GNAT) domain 15 153 4.0E-34 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS06485 ca285c089734a462b96f6aa74f6961a6 181 Gene3D G3DSA:3.40.630.30 4 177 8.7E-25 T 29-03-2018 CXR48_RS06485 ca285c089734a462b96f6aa74f6961a6 181 SUPERFAMILY SSF55729 9 155 1.35E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS06435 68dcf8a02b68862b54ad4800a54a5748 315 Gene3D G3DSA:1.10.3720.10 41 303 1.1E-44 T 29-03-2018 CXR48_RS06435 68dcf8a02b68862b54ad4800a54a5748 315 SUPERFAMILY SSF161098 107 314 2.22E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS06435 68dcf8a02b68862b54ad4800a54a5748 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 315 1.0E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS06435 68dcf8a02b68862b54ad4800a54a5748 315 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 37 89 1.2E-17 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CXR48_RS03330 f911d525c59e0b781f3365205a14f81f 580 SUPERFAMILY SSF51556 82 328 1.51E-11 T 29-03-2018 IPR032466 Metal-dependent hydrolase CXR48_RS03330 f911d525c59e0b781f3365205a14f81f 580 Pfam PF01979 Amidohydrolase family 78 356 7.9E-24 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CXR48_RS03330 f911d525c59e0b781f3365205a14f81f 580 Pfam PF13382 Adenine deaminase C-terminal domain 419 571 1.8E-35 T 29-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CXR48_RS03330 f911d525c59e0b781f3365205a14f81f 580 SUPERFAMILY SSF51338 331 360 5.76E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS03330 f911d525c59e0b781f3365205a14f81f 580 SUPERFAMILY SSF51338 21 82 5.76E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS03330 f911d525c59e0b781f3365205a14f81f 580 Gene3D G3DSA:2.30.40.10 281 365 2.2E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS03330 f911d525c59e0b781f3365205a14f81f 580 Gene3D G3DSA:2.30.40.10 25 84 1.8E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CXR48_RS03330 f911d525c59e0b781f3365205a14f81f 580 Gene3D G3DSA:3.20.20.140 85 273 0.0033 T 29-03-2018 CXR48_RS06745 1bd5c83420313ee88cc837890cd38c9b 209 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 197 6.5E-38 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CXR48_RS06745 1bd5c83420313ee88cc837890cd38c9b 209 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 206 113.244 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CXR48_RS06745 1bd5c83420313ee88cc837890cd38c9b 209 SUPERFAMILY SSF53639 5 205 1.16E-44 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CXR48_RS06745 1bd5c83420313ee88cc837890cd38c9b 209 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 11 202 1.6E-67 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CXR48_RS06745 1bd5c83420313ee88cc837890cd38c9b 209 SMART SM01007 9 198 1.0E-44 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CXR48_RS06745 1bd5c83420313ee88cc837890cd38c9b 209 Gene3D G3DSA:3.40.225.10 3 208 3.0E-44 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CXR48_RS16890 0e077a8a36e7d17d021987f2844660e1 241 Gene3D G3DSA:3.40.10.10 168 241 3.8E-12 T 29-03-2018 IPR035451 Ada-like domain CXR48_RS16890 0e077a8a36e7d17d021987f2844660e1 241 Gene3D G3DSA:1.10.287.540 113 147 2.6E-4 T 29-03-2018 CXR48_RS16890 0e077a8a36e7d17d021987f2844660e1 241 Gene3D G3DSA:1.20.5.400 54 112 0.017 T 29-03-2018 CXR48_RS16890 0e077a8a36e7d17d021987f2844660e1 241 Gene3D G3DSA:1.20.5.170 148 167 0.071 T 29-03-2018 CXR48_RS00225 75c5d5f3bccfee1baa934a5723315b48 275 Pfam PF04468 PSP1 C-terminal conserved region 62 146 7.4E-33 T 29-03-2018 IPR007557 PSP1, C-terminal CXR48_RS01980 1962427314c45d9fb91c3cf50bf16fb5 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS01980 1962427314c45d9fb91c3cf50bf16fb5 252 SUPERFAMILY SSF52540 2 226 1.05E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01980 1962427314c45d9fb91c3cf50bf16fb5 252 Gene3D G3DSA:3.40.50.300 1 245 1.4E-60 T 29-03-2018 CXR48_RS01980 1962427314c45d9fb91c3cf50bf16fb5 252 SMART SM00382 26 213 1.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS01980 1962427314c45d9fb91c3cf50bf16fb5 252 Pfam PF00005 ABC transporter 17 164 2.3E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS00350 911eb4d20d80d73694013122faf66997 526 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 354 498 4.9E-25 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CXR48_RS00350 911eb4d20d80d73694013122faf66997 526 PIRSF PIRSF038958 7 515 1.6E-81 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CXR48_RS00350 911eb4d20d80d73694013122faf66997 526 Pfam PF01943 Polysaccharide biosynthesis protein 13 303 5.2E-56 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CXR48_RS03955 5e2bced2d51f042026df367fdfd6df9e 327 Pfam PF01207 Dihydrouridine synthase (Dus) 15 317 1.4E-47 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CXR48_RS03955 5e2bced2d51f042026df367fdfd6df9e 327 SUPERFAMILY SSF51395 13 317 1.4E-60 T 29-03-2018 CXR48_RS03955 5e2bced2d51f042026df367fdfd6df9e 327 PIRSF PIRSF006621 1 325 1.3E-82 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CXR48_RS03955 5e2bced2d51f042026df367fdfd6df9e 327 Gene3D G3DSA:1.10.1200.80 250 327 9.9E-16 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CXR48_RS03955 5e2bced2d51f042026df367fdfd6df9e 327 Gene3D G3DSA:3.20.20.70 11 249 5.0E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS03955 5e2bced2d51f042026df367fdfd6df9e 327 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 Gene3D G3DSA:3.30.1550.10 3 71 3.7E-37 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 SUPERFAMILY SSF46906 67 140 8.24E-28 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 Gene3D G3DSA:1.10.10.250 72 140 4.0E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 SUPERFAMILY SSF54747 2 84 7.72E-31 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 32.064 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 1.9E-31 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 SMART SM00649 9 140 3.7E-89 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 2.0E-16 T 29-03-2018 CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 2.3E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CXR48_RS00665 f51ce1251ab0398978107ae4d0907227 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 2.8E-65 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS16790 e889ceb47657d50c9011190362bafe58 105 Gene3D G3DSA:3.40.190.10 1 104 1.8E-9 T 29-03-2018 CXR48_RS15885 2449624c23ca36cb8f1722b0d3b359c7 237 SMART SM00382 29 211 5.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15885 2449624c23ca36cb8f1722b0d3b359c7 237 SUPERFAMILY SSF52540 4 212 7.29E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS15885 2449624c23ca36cb8f1722b0d3b359c7 237 Gene3D G3DSA:3.40.50.300 1 224 8.4E-58 T 29-03-2018 CXR48_RS15885 2449624c23ca36cb8f1722b0d3b359c7 237 TIGRFAM TIGR03740 galliderm_ABC: lantibiotic protection ABC transporter, ATP-binding subunit 6 227 1.7E-112 T 29-03-2018 IPR022501 Gallidermin ABC transporter, ATP-binding subunit CXR48_RS15885 2449624c23ca36cb8f1722b0d3b359c7 237 Pfam PF00005 ABC transporter 21 157 5.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS01920 1edcf866a55e4458470fba4c5e61867f 448 SUPERFAMILY SSF103378 3 435 4.18E-96 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CXR48_RS01920 1edcf866a55e4458470fba4c5e61867f 448 Gene3D G3DSA:1.10.4100.10 1 303 8.6E-84 T 29-03-2018 CXR48_RS01920 1edcf866a55e4458470fba4c5e61867f 448 Pfam PF03972 MmgE/PrpD family 11 431 3.8E-93 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CXR48_RS02340 30a85d1709bf2fa53c3a6567307b8532 308 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS02340 30a85d1709bf2fa53c3a6567307b8532 308 Gene3D G3DSA:3.40.50.300 2 240 1.4E-61 T 29-03-2018 CXR48_RS02340 30a85d1709bf2fa53c3a6567307b8532 308 Pfam PF00005 ABC transporter 21 162 1.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS02340 30a85d1709bf2fa53c3a6567307b8532 308 SMART SM00382 30 211 3.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS02340 30a85d1709bf2fa53c3a6567307b8532 308 SUPERFAMILY SSF52540 3 213 1.75E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01480 b6ce35077b90836c74e235cf507a52c7 356 Gene3D G3DSA:1.10.10.10 231 343 0.0028 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01480 b6ce35077b90836c74e235cf507a52c7 356 SUPERFAMILY SSF103642 4 25 1.8E-7 T 29-03-2018 CXR48_RS01480 b6ce35077b90836c74e235cf507a52c7 356 Pfam PF02810 SEC-C motif 6 23 1.1E-9 T 29-03-2018 IPR004027 SEC-C motif CXR48_RS01480 b6ce35077b90836c74e235cf507a52c7 356 Pfam PF05225 helix-turn-helix, Psq domain 294 342 1.8E-15 T 29-03-2018 IPR007889 DNA binding HTH domain, Psq-type GO:0003677 CXR48_RS01480 b6ce35077b90836c74e235cf507a52c7 356 Gene3D G3DSA:3.10.450.50 20 76 7.5E-5 T 29-03-2018 CXR48_RS01480 b6ce35077b90836c74e235cf507a52c7 356 SUPERFAMILY SSF47954 269 340 4.93E-7 T 29-03-2018 IPR013763 Cyclin-like CXR48_RS01480 b6ce35077b90836c74e235cf507a52c7 356 Gene3D G3DSA:3.10.450.50 1 19 1.5E-9 T 29-03-2018 CXR48_RS11640 f15bcbba2513719ca01ae8e493c5eb0f 576 SUPERFAMILY SSF52540 2 219 7.53E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11640 f15bcbba2513719ca01ae8e493c5eb0f 576 Pfam PF13476 AAA domain 4 231 1.7E-18 T 29-03-2018 CXR48_RS11640 f15bcbba2513719ca01ae8e493c5eb0f 576 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 568 2.1E-221 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CXR48_RS11640 f15bcbba2513719ca01ae8e493c5eb0f 576 PIRSF PIRSF003128 1 572 4.0E-196 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CXR48_RS11640 f15bcbba2513719ca01ae8e493c5eb0f 576 Gene3D G3DSA:3.40.50.300 1 189 1.1E-28 T 29-03-2018 CXR48_RS11640 f15bcbba2513719ca01ae8e493c5eb0f 576 Gene3D G3DSA:3.40.50.300 203 541 5.3E-18 T 29-03-2018 CXR48_RS11640 f15bcbba2513719ca01ae8e493c5eb0f 576 SUPERFAMILY SSF52540 4 50 1.43E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS11640 f15bcbba2513719ca01ae8e493c5eb0f 576 SUPERFAMILY SSF52540 311 521 1.43E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS15320 d8cb5951fa1fe9377bd33d6be3ac13ed 121 SMART SM00493 6 80 1.5E-10 T 29-03-2018 IPR006171 TOPRIM domain CXR48_RS15320 d8cb5951fa1fe9377bd33d6be3ac13ed 121 SUPERFAMILY SSF110455 6 108 9.15E-34 T 29-03-2018 CXR48_RS15320 d8cb5951fa1fe9377bd33d6be3ac13ed 121 Gene3D G3DSA:3.40.1360.20 3 118 4.1E-19 T 29-03-2018 CXR48_RS15320 d8cb5951fa1fe9377bd33d6be3ac13ed 121 Pfam PF13155 Toprim-like 9 88 7.3E-6 T 29-03-2018 CXR48_RS08925 ee890268c8f4254b97af52e65a4cfc95 123 SUPERFAMILY SSF49764 27 114 8.02E-6 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS08925 ee890268c8f4254b97af52e65a4cfc95 123 Gene3D G3DSA:2.60.40.790 22 114 1.6E-7 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS11295 fb3945135480d558fde09d46c492fc49 449 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 106 120 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CXR48_RS11295 fb3945135480d558fde09d46c492fc49 449 SUPERFAMILY SSF53686 46 436 2.33E-51 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS11295 fb3945135480d558fde09d46c492fc49 449 Gene3D G3DSA:3.40.50.1100 74 249 1.5E-23 T 29-03-2018 CXR48_RS11295 fb3945135480d558fde09d46c492fc49 449 Gene3D G3DSA:3.40.50.1100 250 438 6.7E-20 T 29-03-2018 CXR48_RS11295 fb3945135480d558fde09d46c492fc49 449 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 449 232.688 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CXR48_RS11295 fb3945135480d558fde09d46c492fc49 449 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 76 395 5.8E-47 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CXR48_RS11295 fb3945135480d558fde09d46c492fc49 449 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 10 435 2.8E-212 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CXR48_RS15990 c5e51a10eb3aa917960e4277de4fb0d1 309 Gene3D G3DSA:3.40.50.720 1 174 6.3E-31 T 29-03-2018 CXR48_RS15990 c5e51a10eb3aa917960e4277de4fb0d1 309 PRINTS PR01713 Nucleotide sugar epimerase signature 220 235 2.1E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CXR48_RS15990 c5e51a10eb3aa917960e4277de4fb0d1 309 PRINTS PR01713 Nucleotide sugar epimerase signature 197 212 2.1E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CXR48_RS15990 c5e51a10eb3aa917960e4277de4fb0d1 309 PRINTS PR01713 Nucleotide sugar epimerase signature 267 284 2.1E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CXR48_RS15990 c5e51a10eb3aa917960e4277de4fb0d1 309 Gene3D G3DSA:3.90.25.10 175 307 3.0E-26 T 29-03-2018 CXR48_RS15990 c5e51a10eb3aa917960e4277de4fb0d1 309 SUPERFAMILY SSF51735 1 304 1.07E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15990 c5e51a10eb3aa917960e4277de4fb0d1 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 226 1.6E-47 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CXR48_RS08430 af19c0c8cded6ef41f8f77016ebf3b23 263 SUPERFAMILY SSF55021 6 71 4.58E-7 T 29-03-2018 CXR48_RS08430 af19c0c8cded6ef41f8f77016ebf3b23 263 Pfam PF11868 Protein of unknown function (DUF3388) 72 261 1.4E-104 T 29-03-2018 IPR024514 Domain of unknown function DUF3388 CXR48_RS08430 af19c0c8cded6ef41f8f77016ebf3b23 263 PIRSF PIRSF021288 1 262 4.7E-145 T 29-03-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain CXR48_RS08430 af19c0c8cded6ef41f8f77016ebf3b23 263 Gene3D G3DSA:3.30.70.260 12 85 3.4E-4 T 29-03-2018 CXR48_RS04590 9a87cd40970cc782d4cd7d7c2cbabb59 302 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 15 300 6.2E-88 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS04590 9a87cd40970cc782d4cd7d7c2cbabb59 302 Gene3D G3DSA:3.30.2350.10 82 301 2.1E-67 T 29-03-2018 CXR48_RS04590 9a87cd40970cc782d4cd7d7c2cbabb59 302 SUPERFAMILY SSF55120 76 298 5.12E-68 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS04590 9a87cd40970cc782d4cd7d7c2cbabb59 302 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS04590 9a87cd40970cc782d4cd7d7c2cbabb59 302 Pfam PF00849 RNA pseudouridylate synthase 91 244 3.2E-33 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CXR48_RS04590 9a87cd40970cc782d4cd7d7c2cbabb59 302 SMART SM00363 19 82 0.0047 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS18270 fcda58c8ca43b8611a4492c855ecf272 452 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 435 2.9E-204 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CXR48_RS18270 fcda58c8ca43b8611a4492c855ecf272 452 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 435 2.9E-204 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS18270 fcda58c8ca43b8611a4492c855ecf272 452 Pfam PF02378 Phosphotransferase system, EIIC 29 359 4.3E-79 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS18270 fcda58c8ca43b8611a4492c855ecf272 452 PIRSF PIRSF006351 1 443 1.7E-156 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS08540 9da40f90efaf4dba3fe28e2f8211e34d 82 Gene3D G3DSA:1.10.1200.10 5 82 1.8E-12 T 29-03-2018 CXR48_RS08540 9da40f90efaf4dba3fe28e2f8211e34d 82 Pfam PF00550 Phosphopantetheine attachment site 11 73 2.2E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS08540 9da40f90efaf4dba3fe28e2f8211e34d 82 SUPERFAMILY SSF47336 1 79 4.71E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CXR48_RS17315 93cfb6b14134edcc77433d3f18d22ba4 134 Pfam PF02082 Transcriptional regulator 1 78 9.1E-19 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CXR48_RS17315 93cfb6b14134edcc77433d3f18d22ba4 134 Gene3D G3DSA:1.10.10.10 1 133 4.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17315 93cfb6b14134edcc77433d3f18d22ba4 134 SUPERFAMILY SSF46785 5 129 3.42E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 SUPERFAMILY SSF52540 295 528 5.97E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 Pfam PF12848 ABC transporter 224 309 5.5E-20 T 29-03-2018 IPR032781 ABC-transporter extension domain CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 Gene3D G3DSA:3.40.50.300 285 538 8.8E-37 T 29-03-2018 CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 Pfam PF00005 ABC transporter 335 468 4.6E-14 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 Pfam PF00005 ABC transporter 18 184 2.6E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 SMART SM00382 344 525 0.91 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 SMART SM00382 26 228 1.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 SUPERFAMILY SSF52540 125 249 8.26E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 SUPERFAMILY SSF52540 2 92 8.26E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS07125 1ca1ee92fcc80f789bc2c5483c6d4726 539 Gene3D G3DSA:3.40.50.300 1 284 4.4E-55 T 29-03-2018 CXR48_RS15195 2f7f544d03aeba67638f3c04b0accaf5 284 Pfam PF00294 pfkB family carbohydrate kinase 10 263 2.8E-35 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CXR48_RS15195 2f7f544d03aeba67638f3c04b0accaf5 284 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 221 234 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CXR48_RS15195 2f7f544d03aeba67638f3c04b0accaf5 284 SUPERFAMILY SSF53613 1 264 5.3E-51 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS15195 2f7f544d03aeba67638f3c04b0accaf5 284 Gene3D G3DSA:3.40.1190.20 1 273 5.2E-44 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS13240 fd1a269e4d1e5135100a50b10c7c8a6e 71 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 21.502 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 CXR48_RS13240 fd1a269e4d1e5135100a50b10c7c8a6e 71 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 8.5E-33 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 CXR48_RS13240 fd1a269e4d1e5135100a50b10c7c8a6e 71 Pfam PF14098 Small, acid-soluble spore protein I 3 66 5.6E-30 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 CXR48_RS13315 725eea436f8612eb9e30cea315d78ada 361 SUPERFAMILY SSF101821 73 182 1.1E-33 T 29-03-2018 CXR48_RS13315 725eea436f8612eb9e30cea315d78ada 361 PIRSF PIRSF001123 4 361 1.3E-148 T 29-03-2018 IPR008007 Peptidase M42 CXR48_RS13315 725eea436f8612eb9e30cea315d78ada 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 2.4E-117 T 29-03-2018 IPR008007 Peptidase M42 CXR48_RS13315 725eea436f8612eb9e30cea315d78ada 361 Gene3D G3DSA:2.40.30.40 72 163 7.4E-34 T 29-03-2018 IPR023367 Peptidase M42, domain 2 CXR48_RS13315 725eea436f8612eb9e30cea315d78ada 361 Gene3D G3DSA:3.40.630.10 165 359 1.0E-45 T 29-03-2018 CXR48_RS13315 725eea436f8612eb9e30cea315d78ada 361 SUPERFAMILY SSF53187 6 83 3.87E-73 T 29-03-2018 CXR48_RS13315 725eea436f8612eb9e30cea315d78ada 361 SUPERFAMILY SSF53187 174 358 3.87E-73 T 29-03-2018 CXR48_RS13475 10ec5f22a265169c5f6136c36ce6bdc1 136 PIRSF PIRSF021328 1 136 3.7E-49 T 29-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 CXR48_RS13475 10ec5f22a265169c5f6136c36ce6bdc1 136 Pfam PF11208 Protein of unknown function (DUF2992) 3 136 5.6E-44 T 29-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 CXR48_RS07970 1ea10992e738bc8e7a9e56d497a6c1fe 90 Pfam PF00886 Ribosomal protein S16 9 67 3.1E-26 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07970 1ea10992e738bc8e7a9e56d497a6c1fe 90 SUPERFAMILY SSF54565 2 86 1.31E-34 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07970 1ea10992e738bc8e7a9e56d497a6c1fe 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 29-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS07970 1ea10992e738bc8e7a9e56d497a6c1fe 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.6E-35 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07970 1ea10992e738bc8e7a9e56d497a6c1fe 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.113 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS07970 1ea10992e738bc8e7a9e56d497a6c1fe 90 Gene3D G3DSA:3.30.1320.10 2 85 4.4E-35 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS15220 91c7d2f732a2254e5735441bd2935659 308 SUPERFAMILY SSF46955 1 111 1.25E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS15220 91c7d2f732a2254e5735441bd2935659 308 SMART SM00422 1 70 1.8E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS15220 91c7d2f732a2254e5735441bd2935659 308 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.2E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS15220 91c7d2f732a2254e5735441bd2935659 308 Gene3D G3DSA:1.10.1660.10 1 137 3.4E-24 T 29-03-2018 CXR48_RS16905 11876e5be6720123aebe470c2553b8e1 382 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 62 300 1.2E-77 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CXR48_RS16905 11876e5be6720123aebe470c2553b8e1 382 SMART SM00854 60 300 5.9E-93 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CXR48_RS16905 11876e5be6720123aebe470c2553b8e1 382 Gene3D G3DSA:3.60.21.10 45 364 1.3E-57 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS16905 11876e5be6720123aebe470c2553b8e1 382 SUPERFAMILY SSF56300 62 308 1.97E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS01660 b6f0e75be7c0541788d300317ed44095 94 Pfam PF12197 Bacillus cereus group antimicrobial protein 49 94 1.9E-25 T 29-03-2018 IPR020976 Antimicrobial peptide, lci CXR48_RS10110 7447bcb4688886622fb9f7f9c6c4d555 223 Gene3D G3DSA:3.30.420.10 75 214 1.3E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS10110 7447bcb4688886622fb9f7f9c6c4d555 223 Pfam PF13456 Reverse transcriptase-like 79 204 3.0E-15 T 29-03-2018 CXR48_RS10110 7447bcb4688886622fb9f7f9c6c4d555 223 SUPERFAMILY SSF53098 73 207 1.39E-21 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CXR48_RS16785 a6b3035d4a291771f473a8a30eb2f803 706 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 415 704 1.7E-75 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CXR48_RS16785 a6b3035d4a291771f473a8a30eb2f803 706 Pfam PF04122 Putative cell wall binding repeat 2 254 340 3.1E-7 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CXR48_RS16785 a6b3035d4a291771f473a8a30eb2f803 706 Pfam PF04122 Putative cell wall binding repeat 2 64 150 3.1E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CXR48_RS16785 a6b3035d4a291771f473a8a30eb2f803 706 Pfam PF04122 Putative cell wall binding repeat 2 163 242 6.1E-18 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CXR48_RS16785 a6b3035d4a291771f473a8a30eb2f803 706 Pfam PF08486 Stage II sporulation protein 416 492 1.7E-22 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CXR48_RS05155 69fb6ac52e6a068f748720be2997299c 478 Gene3D G3DSA:2.30.38.10 299 374 9.6E-15 T 29-03-2018 CXR48_RS05155 69fb6ac52e6a068f748720be2997299c 478 Pfam PF00501 AMP-binding enzyme 8 381 2.0E-51 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS05155 69fb6ac52e6a068f748720be2997299c 478 SUPERFAMILY SSF56801 9 473 3.27E-98 T 29-03-2018 CXR48_RS05155 69fb6ac52e6a068f748720be2997299c 478 Gene3D G3DSA:3.40.50.980 1 151 1.5E-25 T 29-03-2018 CXR48_RS05155 69fb6ac52e6a068f748720be2997299c 478 Gene3D G3DSA:3.30.300.30 377 477 1.8E-23 T 29-03-2018 CXR48_RS05155 69fb6ac52e6a068f748720be2997299c 478 Pfam PF13193 AMP-binding enzyme C-terminal domain 390 460 2.6E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS05155 69fb6ac52e6a068f748720be2997299c 478 Gene3D G3DSA:3.40.50.980 152 298 4.6E-28 T 29-03-2018 CXR48_RS16150 d7ca3a2f489c95309ea5b76f5d29dde9 202 Pfam PF02397 Bacterial sugar transferase 4 178 2.5E-61 T 29-03-2018 IPR003362 Bacterial sugar transferase CXR48_RS17450 3a5380755c9207f73dcdf7dc6831c2c8 180 Hamap MF_00800 UPF0340 protein . 1 180 92.501 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CXR48_RS17450 3a5380755c9207f73dcdf7dc6831c2c8 180 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 9 177 1.3E-67 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CXR48_RS17450 3a5380755c9207f73dcdf7dc6831c2c8 180 PIRSF PIRSF007510 1 180 2.7E-77 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CXR48_RS17450 3a5380755c9207f73dcdf7dc6831c2c8 180 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 14 180 1.0E-75 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CXR48_RS17450 3a5380755c9207f73dcdf7dc6831c2c8 180 Pfam PF04260 Protein of unknown function (DUF436) 8 177 3.1E-74 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CXR48_RS17450 3a5380755c9207f73dcdf7dc6831c2c8 180 SUPERFAMILY SSF110710 1 179 3.92E-76 T 29-03-2018 CXR48_RS17450 3a5380755c9207f73dcdf7dc6831c2c8 180 Gene3D G3DSA:3.40.50.10360 3 179 9.3E-78 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CXR48_RS02425 31dea2a1706bda4eb2f4a3a78c3b344e 93 Gene3D G3DSA:1.10.1220.10 8 58 1.2E-11 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CXR48_RS02425 31dea2a1706bda4eb2f4a3a78c3b344e 93 Pfam PF01402 Ribbon-helix-helix protein, copG family 12 45 5.2E-6 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CXR48_RS02425 31dea2a1706bda4eb2f4a3a78c3b344e 93 SUPERFAMILY SSF47598 9 47 5.44E-6 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CXR48_RS12110 449f24d61b9372e6d2b50f6fbe4fbf5f 168 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 29 157 5.8E-40 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CXR48_RS12110 449f24d61b9372e6d2b50f6fbe4fbf5f 168 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 14 159 30.804 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CXR48_RS08845 3501a4a208f4ff38e37662ef3bf205c5 273 Pfam PF05908 Poly-gamma-glutamate hydrolase 76 263 3.6E-64 T 29-03-2018 IPR008585 Poly-gamma-glutamate hydrolase CXR48_RS12250 cdbc395aa00e729e7b442fb97694dee2 379 SUPERFAMILY SSF102114 3 376 4.19E-119 T 29-03-2018 CXR48_RS12250 cdbc395aa00e729e7b442fb97694dee2 379 SMART SM00729 1 222 1.4E-61 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CXR48_RS12250 cdbc395aa00e729e7b442fb97694dee2 379 Pfam PF04055 Radical SAM superfamily 6 176 7.7E-23 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS12250 cdbc395aa00e729e7b442fb97694dee2 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 2 367 5.2E-160 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CXR48_RS12250 cdbc395aa00e729e7b442fb97694dee2 379 Pfam PF06969 HemN C-terminal domain 301 364 2.2E-14 T 29-03-2018 IPR010723 HemN, C-terminal CXR48_RS12250 cdbc395aa00e729e7b442fb97694dee2 379 Gene3D G3DSA:3.20.20.70 3 324 2.2E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS10070 ee1278469d15251e438aa1ee77dab013 202 SMART SM00471 22 138 5.6E-5 T 29-03-2018 IPR003607 HD/PDEase domain CXR48_RS10070 ee1278469d15251e438aa1ee77dab013 202 Gene3D G3DSA:1.10.3210.10 2 198 7.4E-17 T 29-03-2018 CXR48_RS10070 ee1278469d15251e438aa1ee77dab013 202 Pfam PF01966 HD domain 29 128 8.7E-9 T 29-03-2018 IPR006674 HD domain CXR48_RS10070 ee1278469d15251e438aa1ee77dab013 202 SUPERFAMILY SSF109604 3 197 1.29E-50 T 29-03-2018 CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 Gene3D G3DSA:1.20.1250.20 1 178 1.7E-32 T 29-03-2018 CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 Gene3D G3DSA:1.20.1250.20 241 503 1.7E-33 T 29-03-2018 CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 Pfam PF07690 Major Facilitator Superfamily 3 391 5.3E-56 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 1 485 1.3E-190 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 SUPERFAMILY SSF103473 462 495 1.44E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 SUPERFAMILY SSF103473 2 180 1.44E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 SUPERFAMILY SSF103473 230 401 1.44E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 284 308 9.0E-8 T 29-03-2018 CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 90 110 9.0E-8 T 29-03-2018 CXR48_RS04495 9e5193c54c09ce8f98e762242463b22a 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 144 9.0E-8 T 29-03-2018 CXR48_RS01350 2ed900abd1016a5a5c3cedfe79e2a219 315 Gene3D G3DSA:3.20.20.330 1 315 1.8E-109 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CXR48_RS01350 2ed900abd1016a5a5c3cedfe79e2a219 315 PIRSF PIRSF037505 2 105 7.0E-5 T 29-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CXR48_RS01350 2ed900abd1016a5a5c3cedfe79e2a219 315 PIRSF PIRSF037505 262 313 0.014 T 29-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CXR48_RS01350 2ed900abd1016a5a5c3cedfe79e2a219 315 Pfam PF02574 Homocysteine S-methyltransferase 14 307 8.8E-83 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CXR48_RS01350 2ed900abd1016a5a5c3cedfe79e2a219 315 SUPERFAMILY SSF82282 3 312 5.23E-90 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CXR48_RS01120 92534b076a38c14c9d1c6df78bb9e953 217 Pfam PF13346 ABC-2 family transporter protein 3 212 1.9E-34 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like CXR48_RS12025 93156579226ccb6462c842cc9eb78166 254 Pfam PF06691 Protein of unknown function (DUF1189) 5 244 1.1E-65 T 29-03-2018 IPR009574 Protein of unknown function DUF1189 CXR48_RS17935 9eac98a69da164c17f53c50efd98d7bf 474 Pfam PF05159 Capsule polysaccharide biosynthesis protein 308 392 8.1E-7 T 29-03-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 CXR48_RS17935 9eac98a69da164c17f53c50efd98d7bf 474 Gene3D G3DSA:3.40.50.2000 169 454 1.7E-11 T 29-03-2018 CXR48_RS17935 9eac98a69da164c17f53c50efd98d7bf 474 SUPERFAMILY SSF53756 178 446 5.89E-21 T 29-03-2018 CXR48_RS12095 ce0851e138291af7756195d287566d51 120 PIRSF PIRSF000025 1 120 8.1E-40 T 29-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 CXR48_RS12095 ce0851e138291af7756195d287566d51 120 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 49 116 1.3E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS12095 ce0851e138291af7756195d287566d51 120 SUPERFAMILY SSF46626 7 118 1.21E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS12095 ce0851e138291af7756195d287566d51 120 Gene3D G3DSA:1.10.760.10 27 120 9.0E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CXR48_RS00320 67f043596b62b3bb776d30df7e9ecf98 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CXR48_RS00320 67f043596b62b3bb776d30df7e9ecf98 317 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 317 51.301 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CXR48_RS00320 67f043596b62b3bb776d30df7e9ecf98 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 316 9.0E-27 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CXR48_RS00320 67f043596b62b3bb776d30df7e9ecf98 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 1.1E-131 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CXR48_RS00320 67f043596b62b3bb776d30df7e9ecf98 317 SMART SM01400 10 126 1.9E-82 T 29-03-2018 CXR48_RS00320 67f043596b62b3bb776d30df7e9ecf98 317 Gene3D G3DSA:3.40.50.2020 160 317 1.2E-50 T 29-03-2018 CXR48_RS00320 67f043596b62b3bb776d30df7e9ecf98 317 Gene3D G3DSA:3.40.50.2020 7 159 1.1E-69 T 29-03-2018 CXR48_RS00320 67f043596b62b3bb776d30df7e9ecf98 317 SUPERFAMILY SSF53271 75 308 1.63E-68 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS00320 67f043596b62b3bb776d30df7e9ecf98 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 1.4E-52 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CXR48_RS18335 139926db15fa5c83c4eb750b9cf42835 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 293 307 1.5E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS18335 139926db15fa5c83c4eb750b9cf42835 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 1.5E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS18335 139926db15fa5c83c4eb750b9cf42835 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 434 446 1.5E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS18335 139926db15fa5c83c4eb750b9cf42835 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 373 1.5E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS18335 139926db15fa5c83c4eb750b9cf42835 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 1.5E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS18335 139926db15fa5c83c4eb750b9cf42835 466 SUPERFAMILY SSF51445 6 460 2.65E-166 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CXR48_RS18335 139926db15fa5c83c4eb750b9cf42835 466 Pfam PF00232 Glycosyl hydrolase family 1 8 465 2.7E-139 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CXR48_RS18335 139926db15fa5c83c4eb750b9cf42835 466 Gene3D G3DSA:3.20.20.80 8 466 1.9E-153 T 29-03-2018 CXR48_RS18335 139926db15fa5c83c4eb750b9cf42835 466 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 365 373 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site CXR48_RS11835 9640aad5b9cd3cec699ffbd664cee8eb 223 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 28 58 1.5E-4 T 29-03-2018 IPR023833 Signal peptide, camelysin CXR48_RS11835 9640aad5b9cd3cec699ffbd664cee8eb 223 TIGRFAM TIGR04087 YqxM_for_SipW: YqxM protein 3 192 8.4E-76 T 29-03-2018 IPR023848 Conserved hypothetical protein CHP04087, YqxM CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 Gene3D G3DSA:3.90.1720.10 160 292 2.0E-34 T 29-03-2018 CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 Gene3D G3DSA:3.90.1720.10 4 80 3.2E-11 T 29-03-2018 CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 SUPERFAMILY SSF54001 295 410 3.48E-29 T 29-03-2018 CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 Gene3D G3DSA:3.90.1720.10 293 410 1.5E-27 T 29-03-2018 CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 SUPERFAMILY SSF54001 165 286 1.18E-37 T 29-03-2018 CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 Gene3D G3DSA:2.30.260.10 81 159 1.5E-16 T 29-03-2018 CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 Pfam PF00877 NlpC/P60 family 179 284 9.9E-30 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 Pfam PF00877 NlpC/P60 family 307 407 9.4E-20 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 Pfam PF00877 NlpC/P60 family 47 154 7.9E-23 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CXR48_RS16895 d58de3a2445b4cc71019e540cf818fac 411 SUPERFAMILY SSF54001 38 158 2.5E-31 T 29-03-2018 CXR48_RS04925 3226241f99f7829b114b485828ce3338 419 Pfam PF12698 ABC-2 family transporter protein 19 391 4.3E-54 T 29-03-2018 CXR48_RS04925 3226241f99f7829b114b485828ce3338 419 Gene3D G3DSA:3.40.190.10 47 161 6.1E-15 T 29-03-2018 CXR48_RS05610 3c3cceecec24c9d30b5fed206a8060ad 544 PIRSF PIRSF002741 1 544 3.4E-149 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CXR48_RS05610 3c3cceecec24c9d30b5fed206a8060ad 544 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 87 109 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CXR48_RS05610 3c3cceecec24c9d30b5fed206a8060ad 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 466 3.5E-90 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CXR48_RS05610 3c3cceecec24c9d30b5fed206a8060ad 544 Gene3D G3DSA:3.40.190.10 209 306 3.0E-24 T 29-03-2018 CXR48_RS05610 3c3cceecec24c9d30b5fed206a8060ad 544 Gene3D G3DSA:3.10.105.10 307 516 3.3E-57 T 29-03-2018 CXR48_RS05610 3c3cceecec24c9d30b5fed206a8060ad 544 Gene3D G3DSA:3.90.76.10 50 208 6.4E-43 T 29-03-2018 CXR48_RS05610 3c3cceecec24c9d30b5fed206a8060ad 544 SUPERFAMILY SSF53850 35 540 6.7E-137 T 29-03-2018 CXR48_RS14475 623813c0404e8de1fb55815033f57969 386 Pfam PF01594 AI-2E family transporter 32 363 4.6E-85 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CXR48_RS13455 f1d4a686d343a6c45746f42cf8a56ff6 239 Gene3D G3DSA:3.40.50.2300 1 132 1.2E-39 T 29-03-2018 CXR48_RS13455 f1d4a686d343a6c45746f42cf8a56ff6 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 3.9E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS13455 f1d4a686d343a6c45746f42cf8a56ff6 239 SMART SM00862 156 232 1.0E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS13455 f1d4a686d343a6c45746f42cf8a56ff6 239 SMART SM00448 3 114 1.5E-49 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS13455 f1d4a686d343a6c45746f42cf8a56ff6 239 SUPERFAMILY SSF46894 133 233 1.64E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS13455 f1d4a686d343a6c45746f42cf8a56ff6 239 Gene3D G3DSA:1.10.10.10 133 239 6.5E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13455 f1d4a686d343a6c45746f42cf8a56ff6 239 Pfam PF00072 Response regulator receiver domain 5 114 1.9E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS13455 f1d4a686d343a6c45746f42cf8a56ff6 239 SUPERFAMILY SSF52172 2 122 4.98E-44 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS03670 b6673e1349d3ed91bfb91776418197eb 115 Pfam PF11181 Heat induced stress protein YflT 5 104 7.3E-31 T 29-03-2018 IPR025889 General stress protein 17M-like domain CXR48_RS15480 1341f331b9f8ecd9de21b2c9b97399a4 370 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 201 364 1.1E-26 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CXR48_RS15480 1341f331b9f8ecd9de21b2c9b97399a4 370 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 366 6.2E-91 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CXR48_RS09565 93378a6810b69828aa9279adb6683911 322 TIGRFAM TIGR00841 bass: bile acid transporter 8 309 2.5E-103 T 29-03-2018 IPR004710 Bile acid:sodium symporter CXR48_RS09565 93378a6810b69828aa9279adb6683911 322 Pfam PF01758 Sodium Bile acid symporter family 41 220 7.4E-48 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CXR48_RS09050 8d27e3e818cd5d5db27ceffb6fc2b4b7 202 Pfam PF13761 Domain of unknown function (DUF4166) 16 194 5.8E-53 T 29-03-2018 IPR025311 Domain of unknown function DUF4166 CXR48_RS11845 dfa3f0bdaff64d367a07241defcf17be 59 Pfam PF14038 YqzE-like protein 2 54 6.0E-28 T 29-03-2018 IPR025622 YqzE-like protein CXR48_RS12500 18bdc473c33c0c91a8452f4e4efa9dfc 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 4.0E-19 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CXR48_RS12500 18bdc473c33c0c91a8452f4e4efa9dfc 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 45 2.9E-15 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CXR48_RS09920 d989fec77e3d03dc46302c0c28ef4700 339 Gene3D G3DSA:2.130.10.10 24 304 9.1E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CXR48_RS09920 d989fec77e3d03dc46302c0c28ef4700 339 SUPERFAMILY SSF75011 130 258 9.42E-5 T 29-03-2018 CXR48_RS09920 d989fec77e3d03dc46302c0c28ef4700 339 SUPERFAMILY SSF75011 292 324 9.42E-5 T 29-03-2018 CXR48_RS14010 85fc2c5fdee690a7cca0b9f62b6b294a 394 Gene3D G3DSA:1.20.1250.20 2 182 3.5E-22 T 29-03-2018 CXR48_RS14010 85fc2c5fdee690a7cca0b9f62b6b294a 394 Gene3D G3DSA:1.20.1250.20 193 392 5.6E-27 T 29-03-2018 CXR48_RS14010 85fc2c5fdee690a7cca0b9f62b6b294a 394 Pfam PF07690 Major Facilitator Superfamily 8 266 1.0E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS14010 85fc2c5fdee690a7cca0b9f62b6b294a 394 SUPERFAMILY SSF103473 3 389 1.83E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS17370 78d5e3b8c008894872a1bb0e174e66de 343 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 5 331 9.2E-134 T 29-03-2018 IPR014225 Sporulation stage II, protein D firmicutes CXR48_RS17370 78d5e3b8c008894872a1bb0e174e66de 343 Pfam PF08486 Stage II sporulation protein 68 171 1.0E-23 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CXR48_RS17370 78d5e3b8c008894872a1bb0e174e66de 343 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 71 330 1.2E-70 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CXR48_RS10930 0a82eab6f1f49e6ac4229b18b5377617 82 Gene3D G3DSA:3.30.70.20 2 82 1.3E-9 T 29-03-2018 CXR48_RS10930 0a82eab6f1f49e6ac4229b18b5377617 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 7.4E-21 T 29-03-2018 CXR48_RS10930 0a82eab6f1f49e6ac4229b18b5377617 82 SUPERFAMILY SSF54862 4 73 2.17E-13 T 29-03-2018 CXR48_RS10930 0a82eab6f1f49e6ac4229b18b5377617 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 5.4E-8 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CXR48_RS10930 0a82eab6f1f49e6ac4229b18b5377617 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 5.4E-8 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CXR48_RS10930 0a82eab6f1f49e6ac4229b18b5377617 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 5.4E-8 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CXR48_RS00240 cba9c96c5e58c8f297da531af7889198 99 SUPERFAMILY SSF82771 5 80 6.15E-14 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS00240 cba9c96c5e58c8f297da531af7889198 99 SMART SM00465 5 83 5.3E-5 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS00240 cba9c96c5e58c8f297da531af7889198 99 Gene3D G3DSA:3.40.1440.10 3 90 2.8E-9 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS00240 cba9c96c5e58c8f297da531af7889198 99 Pfam PF01541 GIY-YIG catalytic domain 6 77 9.1E-19 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 Pfam PF00722 Glycosyl hydrolases family 16 56 238 2.7E-45 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 Gene3D G3DSA:2.60.120.200 156 243 4.4E-20 T 29-03-2018 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 Gene3D G3DSA:2.60.120.200 24 155 2.5E-27 T 29-03-2018 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 ProSitePatterns PS01034 Glycosyl hydrolases family 16 active sites. 134 144 - T 29-03-2018 IPR008263 Glycoside hydrolase, family 16, active site GO:0004553|GO:0005975 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 SUPERFAMILY SSF49899 34 242 1.39E-61 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 165 182 2.7E-80 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 131 146 2.7E-80 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 205 227 2.7E-80 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 229 241 2.7E-80 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 185 202 2.7E-80 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 147 160 2.7E-80 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 110 126 2.7E-80 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 CXR48_RS18475 73a3409dc8cd1e9c85eeed5ef8e41d24 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 91 109 2.7E-80 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 CXR48_RS04380 39f7560871784b796a8e2a619f2b2011 321 Pfam PF00005 ABC transporter 33 184 1.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS04380 39f7560871784b796a8e2a619f2b2011 321 Gene3D G3DSA:3.40.50.300 2 321 3.0E-81 T 29-03-2018 CXR48_RS04380 39f7560871784b796a8e2a619f2b2011 321 SMART SM00382 41 241 5.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04380 39f7560871784b796a8e2a619f2b2011 321 SUPERFAMILY SSF52540 5 255 2.84E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04380 39f7560871784b796a8e2a619f2b2011 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 2.1E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS04380 39f7560871784b796a8e2a619f2b2011 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 8.3E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS04380 39f7560871784b796a8e2a619f2b2011 321 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15630 cdb785b7cc0997f9f1eb15e9f9a5c3c3 618 SUPERFAMILY SSF53649 241 616 7.1E-64 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CXR48_RS15630 cdb785b7cc0997f9f1eb15e9f9a5c3c3 618 Pfam PF00884 Sulfatase 243 535 7.9E-38 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CXR48_RS15630 cdb785b7cc0997f9f1eb15e9f9a5c3c3 618 Gene3D G3DSA:3.40.720.10 238 545 2.4E-41 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CXR48_RS15630 cdb785b7cc0997f9f1eb15e9f9a5c3c3 618 PIRSF PIRSF005091 1 618 1.1E-174 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like CXR48_RS08385 f135d9f3462d1c6b043ae09c185aff31 788 SMART SM00843 716 781 2.4E-40 T 29-03-2018 IPR018541 FtsK gamma domain CXR48_RS08385 f135d9f3462d1c6b043ae09c185aff31 788 Gene3D G3DSA:1.10.10.10 719 772 4.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08385 f135d9f3462d1c6b043ae09c185aff31 788 SUPERFAMILY SSF46785 717 783 9.66E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08385 f135d9f3462d1c6b043ae09c185aff31 788 SUPERFAMILY SSF52540 398 693 4.78E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08385 f135d9f3462d1c6b043ae09c185aff31 788 Pfam PF09397 Ftsk gamma domain 719 778 2.7E-29 T 29-03-2018 IPR018541 FtsK gamma domain CXR48_RS08385 f135d9f3462d1c6b043ae09c185aff31 788 SMART SM00382 460 642 1.4E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS08385 f135d9f3462d1c6b043ae09c185aff31 788 Gene3D G3DSA:3.40.50.300 214 662 9.4E-57 T 29-03-2018 CXR48_RS08385 f135d9f3462d1c6b043ae09c185aff31 788 Pfam PF01580 FtsK/SpoIIIE family 425 621 3.9E-65 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CXR48_RS08180 56db9de8d6c834c6649bb4d490806e5f 363 Pfam PF00448 SRP54-type protein, GTPase domain 173 362 8.1E-46 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS08180 56db9de8d6c834c6649bb4d490806e5f 363 SUPERFAMILY SSF52540 173 362 6.04E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS08180 56db9de8d6c834c6649bb4d490806e5f 363 Gene3D G3DSA:3.40.50.300 168 351 1.8E-20 T 29-03-2018 CXR48_RS08180 56db9de8d6c834c6649bb4d490806e5f 363 SMART SM00962 172 363 5.5E-53 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CXR48_RS08180 56db9de8d6c834c6649bb4d490806e5f 363 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 259 7.7E-61 T 29-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 CXR48_RS03255 f9116c40ee42fb044e1c7af89e3f1c20 184 Hamap MF_01515 UPF0316 protein . 10 178 30.516 T 29-03-2018 IPR022930 Protein of unknown function UPF0316 CXR48_RS03255 f9116c40ee42fb044e1c7af89e3f1c20 184 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 118 170 5.5E-6 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CXR48_RS18090 34f00f8e078798fc2c2dcd0d70f50377 81 Pfam PF04226 Transglycosylase associated protein 33 78 1.2E-9 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CXR48_RS12735 faa8852fb25046bf3dcc1d175e04417f 108 Pfam PF06305 Lipopolysaccharide assembly protein A domain 24 80 3.6E-15 T 29-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CXR48_RS14420 7bf3c6abcb060028de46c041b646c451 402 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 186 214 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CXR48_RS14420 7bf3c6abcb060028de46c041b646c451 402 Pfam PF00465 Iron-containing alcohol dehydrogenase 19 385 2.0E-116 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CXR48_RS14420 7bf3c6abcb060028de46c041b646c451 402 Gene3D G3DSA:1.20.1090.10 197 402 1.7E-56 T 29-03-2018 CXR48_RS14420 7bf3c6abcb060028de46c041b646c451 402 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 273 293 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CXR48_RS14420 7bf3c6abcb060028de46c041b646c451 402 Gene3D G3DSA:3.40.50.1970 19 196 3.8E-46 T 29-03-2018 CXR48_RS14420 7bf3c6abcb060028de46c041b646c451 402 SUPERFAMILY SSF56796 12 395 9.81E-120 T 29-03-2018 CXR48_RS10500 5c9a3bd2e7b182e879d6c2cbb704e3ca 99 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 3.4E-14 T 29-03-2018 IPR019933 DivIVA domain CXR48_RS10500 5c9a3bd2e7b182e879d6c2cbb704e3ca 99 Gene3D G3DSA:1.20.5.1180 28 71 3.5E-4 T 29-03-2018 CXR48_RS10500 5c9a3bd2e7b182e879d6c2cbb704e3ca 99 PIRSF PIRSF029938 1 98 3.7E-39 T 29-03-2018 IPR011229 Cell cycle protein GpsB CXR48_RS10500 5c9a3bd2e7b182e879d6c2cbb704e3ca 99 Pfam PF05103 DivIVA protein 8 68 2.2E-16 T 29-03-2018 IPR007793 DivIVA family CXR48_RS10500 5c9a3bd2e7b182e879d6c2cbb704e3ca 99 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 94 24.219 T 29-03-2018 IPR011229 Cell cycle protein GpsB CXR48_RS17715 7c603813e4c134fa43e83be1307ffd8a 276 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 4 276 41.877 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CXR48_RS17715 7c603813e4c134fa43e83be1307ffd8a 276 Pfam PF01564 Spermine/spermidine synthase domain 59 237 1.9E-70 T 29-03-2018 CXR48_RS17715 7c603813e4c134fa43e83be1307ffd8a 276 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 80 93 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CXR48_RS17715 7c603813e4c134fa43e83be1307ffd8a 276 SUPERFAMILY SSF53335 4 275 3.26E-89 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS17715 7c603813e4c134fa43e83be1307ffd8a 276 Gene3D G3DSA:2.30.140.10 5 52 3.4E-20 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CXR48_RS17715 7c603813e4c134fa43e83be1307ffd8a 276 Gene3D G3DSA:3.40.50.150 56 276 1.2E-44 T 29-03-2018 CXR48_RS17715 7c603813e4c134fa43e83be1307ffd8a 276 TIGRFAM TIGR00417 speE: spermidine synthase 5 270 4.2E-125 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CXR48_RS17715 7c603813e4c134fa43e83be1307ffd8a 276 Pfam PF17284 Spermidine synthase tetramerisation domain 4 56 1.9E-21 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CXR48_RS03675 dab904bdd60f3aa8fa086ed471d7c77e 421 SMART SM00656 111 353 1.8E-53 T 29-03-2018 IPR002022 Pectate lyase CXR48_RS03675 dab904bdd60f3aa8fa086ed471d7c77e 421 Pfam PF00544 Pectate lyase 130 347 9.5E-50 T 29-03-2018 IPR002022 Pectate lyase CXR48_RS03675 dab904bdd60f3aa8fa086ed471d7c77e 421 Gene3D G3DSA:2.160.20.10 22 421 1.2E-91 T 29-03-2018 IPR012334 Pectin lyase fold CXR48_RS03675 dab904bdd60f3aa8fa086ed471d7c77e 421 SUPERFAMILY SSF51126 23 420 2.4E-85 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CXR48_RS16355 9e1b415db9f8db00c063691b71788c6c 157 PRINTS PR00117 Barnase signature 94 112 6.3E-55 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 CXR48_RS16355 9e1b415db9f8db00c063691b71788c6c 157 PRINTS PR00117 Barnase signature 115 134 6.3E-55 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 CXR48_RS16355 9e1b415db9f8db00c063691b71788c6c 157 PRINTS PR00117 Barnase signature 137 155 6.3E-55 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 CXR48_RS16355 9e1b415db9f8db00c063691b71788c6c 157 PRINTS PR00117 Barnase signature 54 71 6.3E-55 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 CXR48_RS16355 9e1b415db9f8db00c063691b71788c6c 157 PRINTS PR00117 Barnase signature 74 91 6.3E-55 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 CXR48_RS16355 9e1b415db9f8db00c063691b71788c6c 157 Pfam PF00545 ribonuclease 67 154 2.7E-23 T 29-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 CXR48_RS16355 9e1b415db9f8db00c063691b71788c6c 157 SUPERFAMILY SSF53933 50 157 1.28E-38 T 29-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CXR48_RS16355 9e1b415db9f8db00c063691b71788c6c 157 PIRSF PIRSF001013 8 157 2.1E-77 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 CXR48_RS16355 9e1b415db9f8db00c063691b71788c6c 157 Gene3D G3DSA:3.10.450.30 50 157 2.3E-35 T 29-03-2018 CXR48_RS09125 e8ff9769eb221dcc26e96d5091dceed5 220 Gene3D G3DSA:3.40.1080.10 3 214 1.6E-70 T 29-03-2018 CXR48_RS09125 e8ff9769eb221dcc26e96d5091dceed5 220 SMART SM00882 6 202 6.6E-78 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS09125 e8ff9769eb221dcc26e96d5091dceed5 220 Pfam PF01144 Coenzyme A transferase 8 201 3.1E-47 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS09125 e8ff9769eb221dcc26e96d5091dceed5 220 SUPERFAMILY SSF100950 3 214 5.8E-74 T 29-03-2018 CXR48_RS09125 e8ff9769eb221dcc26e96d5091dceed5 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 1.8E-97 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CXR48_RS09125 e8ff9769eb221dcc26e96d5091dceed5 220 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CXR48_RS05940 edb7a982246cebee93c11a6e24b682dc 330 Gene3D G3DSA:3.40.50.720 2 165 1.4E-33 T 29-03-2018 CXR48_RS05940 edb7a982246cebee93c11a6e24b682dc 330 SUPERFAMILY SSF51735 1 328 3.36E-96 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS05940 edb7a982246cebee93c11a6e24b682dc 330 Gene3D G3DSA:3.90.25.10 166 330 6.9E-42 T 29-03-2018 CXR48_RS05940 edb7a982246cebee93c11a6e24b682dc 330 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 326 5.8E-130 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CXR48_RS05940 edb7a982246cebee93c11a6e24b682dc 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 1.3E-58 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CXR48_RS17795 14bde0c4fd09e4cd223b3ee63a04ac71 287 Pfam PF03099 Biotin/lipoate A/B protein ligase family 74 184 7.4E-19 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CXR48_RS17795 14bde0c4fd09e4cd223b3ee63a04ac71 287 Gene3D G3DSA:3.30.930.10 6 273 1.2E-46 T 29-03-2018 CXR48_RS17795 14bde0c4fd09e4cd223b3ee63a04ac71 287 SUPERFAMILY SSF55681 6 268 2.49E-70 T 29-03-2018 CXR48_RS17795 14bde0c4fd09e4cd223b3ee63a04ac71 287 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 7 281 50.494 T 29-03-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987 CXR48_RS12730 fdeaaa6bdc1497f562f7ffc9428ee0ae 786 Pfam PF02272 DHHA1 domain 315 437 1.3E-21 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CXR48_RS12730 fdeaaa6bdc1497f562f7ffc9428ee0ae 786 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 566 769 6.3E-66 T 29-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal CXR48_RS12730 fdeaaa6bdc1497f562f7ffc9428ee0ae 786 Gene3D G3DSA:3.90.1640.10 62 237 3.4E-25 T 29-03-2018 CXR48_RS12730 fdeaaa6bdc1497f562f7ffc9428ee0ae 786 Pfam PF01368 DHH family 83 225 4.1E-11 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CXR48_RS12730 fdeaaa6bdc1497f562f7ffc9428ee0ae 786 SUPERFAMILY SSF64182 57 450 1.57E-123 T 29-03-2018 CXR48_RS12730 fdeaaa6bdc1497f562f7ffc9428ee0ae 786 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 559 1.7E-182 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CXR48_RS06890 e4e27868557ee15298fd8f87f579a6db 342 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 5 342 5.3E-156 T 29-03-2018 IPR023897 Spore photoproduct lyase GO:0003913 CXR48_RS06890 e4e27868557ee15298fd8f87f579a6db 342 Gene3D G3DSA:3.20.20.70 23 331 6.5E-12 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS06890 e4e27868557ee15298fd8f87f579a6db 342 SUPERFAMILY SSF102114 85 311 3.14E-7 T 29-03-2018 CXR48_RS01970 a568f3c049e3f99ed2c4c9ba575d392d 317 SUPERFAMILY SSF81345 3 312 3.14E-67 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS01970 a568f3c049e3f99ed2c4c9ba575d392d 317 Pfam PF01032 FecCD transport family 9 311 1.4E-65 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CXR48_RS01970 a568f3c049e3f99ed2c4c9ba575d392d 317 Gene3D G3DSA:1.10.3470.10 2 317 6.1E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 Gene3D G3DSA:1.20.120.530 74 220 1.5E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 SMART SM00345 19 77 1.2E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 75 1.6E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 SMART SM00895 87 211 1.4E-11 T 29-03-2018 IPR011711 GntR, C-terminal CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 SUPERFAMILY SSF48008 83 218 3.14E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.3E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.3E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 Pfam PF07729 FCD domain 89 206 1.2E-20 T 29-03-2018 IPR011711 GntR, C-terminal CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 Gene3D G3DSA:1.10.10.10 2 73 4.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19180 6c2298632f91c2e4513622fd5ebd0714 220 SUPERFAMILY SSF46785 15 81 1.92E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09260 23f59d59c5f37d1c5dd4565d1846f177 491 SUPERFAMILY SSF56601 38 489 2.15E-99 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS09260 23f59d59c5f37d1c5dd4565d1846f177 491 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 36 490 1.3E-140 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS09260 23f59d59c5f37d1c5dd4565d1846f177 491 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 65 470 1.2E-130 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS09260 23f59d59c5f37d1c5dd4565d1846f177 491 Gene3D G3DSA:3.40.710.10 32 491 2.2E-41 T 29-03-2018 CXR48_RS09260 23f59d59c5f37d1c5dd4565d1846f177 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 365 379 6.8E-25 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS09260 23f59d59c5f37d1c5dd4565d1846f177 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 447 460 6.8E-25 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS09260 23f59d59c5f37d1c5dd4565d1846f177 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 380 394 6.8E-25 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS09260 23f59d59c5f37d1c5dd4565d1846f177 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 77 96 6.8E-25 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS09260 23f59d59c5f37d1c5dd4565d1846f177 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 308 330 6.8E-25 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CXR48_RS17515 475e023f3ef3fbf299b47a5801e5db36 318 Pfam PF03547 Membrane transport protein 7 162 1.1E-27 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CXR48_RS17515 475e023f3ef3fbf299b47a5801e5db36 318 Pfam PF03547 Membrane transport protein 166 314 4.0E-24 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CXR48_RS02540 05d45fd924fa3860f538dfde47d48fbe 76 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 2 76 2.2E-14 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CXR48_RS17220 8df5b5a0229651c6ee4c51f9d708ed2e 93 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CXR48_RS17220 8df5b5a0229651c6ee4c51f9d708ed2e 93 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 2.6E-46 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CXR48_RS17220 8df5b5a0229651c6ee4c51f9d708ed2e 93 Gene3D G3DSA:1.10.10.10 2 32 9.4E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17220 8df5b5a0229651c6ee4c51f9d708ed2e 93 Gene3D G3DSA:1.10.260.40 33 86 2.5E-4 T 29-03-2018 CXR48_RS17220 8df5b5a0229651c6ee4c51f9d708ed2e 93 Pfam PF12116 Stage III sporulation protein D 2 82 6.2E-41 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CXR48_RS06545 961d49f0d20612898611dc456e3474ad 347 Gene3D G3DSA:2.10.10.20 147 182 3.9E-4 T 29-03-2018 CXR48_RS06545 961d49f0d20612898611dc456e3474ad 347 Gene3D G3DSA:2.160.20.50 90 146 7.4E-5 T 29-03-2018 CXR48_RS06545 961d49f0d20612898611dc456e3474ad 347 Gene3D G3DSA:2.60.120.40 209 347 7.5E-24 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 Pfam PF00106 short chain dehydrogenase 6 192 1.1E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 SUPERFAMILY SSF51735 1 198 3.06E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.3E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.3E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.3E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 Gene3D G3DSA:3.40.50.720 1 253 2.5E-43 T 29-03-2018 CXR48_RS15005 a19e0d990f8908afa7a30564ed985705 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS17165 3ab5a0515165df78fd9fbab568679281 285 Gene3D G3DSA:3.40.50.1000 1 285 1.8E-46 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS17165 3ab5a0515165df78fd9fbab568679281 285 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 281 1.1E-66 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS17165 3ab5a0515165df78fd9fbab568679281 285 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 281 1.7E-62 T 29-03-2018 IPR000150 Cof family GO:0016787 CXR48_RS17165 3ab5a0515165df78fd9fbab568679281 285 ProSitePatterns PS01229 Hypothetical cof family signature 2. 235 257 - T 29-03-2018 CXR48_RS17165 3ab5a0515165df78fd9fbab568679281 285 SUPERFAMILY SSF56784 1 285 1.95E-68 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS17165 3ab5a0515165df78fd9fbab568679281 285 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 254 9.6E-29 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CXR48_RS17165 3ab5a0515165df78fd9fbab568679281 285 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 29-03-2018 CXR48_RS13420 b04c0f43e35ee95518ddf1329838af82 399 Gene3D G3DSA:1.20.1250.20 197 399 6.7E-21 T 29-03-2018 CXR48_RS13420 b04c0f43e35ee95518ddf1329838af82 399 Gene3D G3DSA:1.20.1250.20 3 196 2.3E-28 T 29-03-2018 CXR48_RS13420 b04c0f43e35ee95518ddf1329838af82 399 Pfam PF07690 Major Facilitator Superfamily 16 321 2.1E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS13420 b04c0f43e35ee95518ddf1329838af82 399 SUPERFAMILY SSF103473 8 393 3.01E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS13415 30a4daf54f55d1396b75da2b8be2e893 128 Gene3D G3DSA:1.10.10.10 14 114 2.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13415 30a4daf54f55d1396b75da2b8be2e893 128 Pfam PF01638 HxlR-like helix-turn-helix 16 104 1.4E-39 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CXR48_RS13415 30a4daf54f55d1396b75da2b8be2e893 128 SUPERFAMILY SSF46785 10 102 4.65E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06480 cb919032c86649b0f4c6cbf88200e499 172 SUPERFAMILY SSF54637 5 154 1.07E-46 T 29-03-2018 IPR029069 HotDog domain CXR48_RS06480 cb919032c86649b0f4c6cbf88200e499 172 Pfam PF03061 Thioesterase superfamily 28 100 4.5E-16 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CXR48_RS06480 cb919032c86649b0f4c6cbf88200e499 172 Gene3D G3DSA:3.10.129.10 5 163 1.7E-49 T 29-03-2018 CXR48_RS03775 7dfb5ba505e9429bcf09d5b617ede195 460 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 391 408 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS03775 7dfb5ba505e9429bcf09d5b617ede195 460 SUPERFAMILY SSF55604 381 451 3.53E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS03775 7dfb5ba505e9429bcf09d5b617ede195 460 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 351 438 1.9E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS03775 7dfb5ba505e9429bcf09d5b617ede195 460 Gene3D G3DSA:3.30.1360.60 380 451 1.1E-25 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS03775 7dfb5ba505e9429bcf09d5b617ede195 460 Pfam PF00367 phosphotransferase system, EIIB 381 413 5.7E-13 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS03775 7dfb5ba505e9429bcf09d5b617ede195 460 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 449 3.7E-181 T 29-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 CXR48_RS03775 7dfb5ba505e9429bcf09d5b617ede195 460 Pfam PF02378 Phosphotransferase system, EIIC 9 293 1.4E-78 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS03605 e352df79d3097123ccde5b49aebcb959 461 Pfam PF13520 Amino acid permease 26 427 2.2E-58 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS03605 e352df79d3097123ccde5b49aebcb959 461 PIRSF PIRSF006060 11 461 3.3E-89 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS06730 c10cd4ffc25f9743954494d7b716be49 398 Pfam PF00155 Aminotransferase class I and II 33 383 1.9E-67 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CXR48_RS06730 c10cd4ffc25f9743954494d7b716be49 398 Gene3D G3DSA:3.90.1150.10 301 387 4.2E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS06730 c10cd4ffc25f9743954494d7b716be49 398 SUPERFAMILY SSF53383 5 386 1.9E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS06730 c10cd4ffc25f9743954494d7b716be49 398 Gene3D G3DSA:3.40.640.10 47 300 3.3E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS13595 cfe72d54db1de3d443c872381edc83ad 167 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CXR48_RS13595 cfe72d54db1de3d443c872381edc83ad 167 SUPERFAMILY SSF52833 1 160 8.02E-43 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS13595 cfe72d54db1de3d443c872381edc83ad 167 Pfam PF08534 Redoxin 19 156 2.3E-21 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CXR48_RS13595 cfe72d54db1de3d443c872381edc83ad 167 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 163 36.701 T 29-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CXR48_RS13595 cfe72d54db1de3d443c872381edc83ad 167 Gene3D G3DSA:3.40.30.10 11 167 7.6E-28 T 29-03-2018 CXR48_RS14555 2617794e399a205c593851e45002f6fd 328 Gene3D G3DSA:1.20.5.110 63 99 8.8E-7 T 29-03-2018 CXR48_RS14555 2617794e399a205c593851e45002f6fd 328 SUPERFAMILY SSF51735 115 250 3.05E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS14555 2617794e399a205c593851e45002f6fd 328 Gene3D G3DSA:1.10.287.70 12 61 5.6E-9 T 29-03-2018 CXR48_RS14555 2617794e399a205c593851e45002f6fd 328 Pfam PF02254 TrkA-N domain 117 237 6.2E-17 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CXR48_RS14555 2617794e399a205c593851e45002f6fd 328 Gene3D G3DSA:3.40.50.720 106 238 2.2E-20 T 29-03-2018 CXR48_RS14555 2617794e399a205c593851e45002f6fd 328 SUPERFAMILY SSF81324 9 134 7.46E-25 T 29-03-2018 CXR48_RS14555 2617794e399a205c593851e45002f6fd 328 Pfam PF07885 Ion channel 22 97 4.0E-15 T 29-03-2018 IPR013099 Potassium channel domain CXR48_RS18370 d1f41b56896ecccc30086d080a7520f2 276 SUPERFAMILY SSF53613 5 275 9.49E-71 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS18370 d1f41b56896ecccc30086d080a7520f2 276 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 7 273 19.897 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CXR48_RS18370 d1f41b56896ecccc30086d080a7520f2 276 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 212 222 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CXR48_RS18370 d1f41b56896ecccc30086d080a7520f2 276 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 6 273 8.1E-86 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CXR48_RS18370 d1f41b56896ecccc30086d080a7520f2 276 Pfam PF01256 Carbohydrate kinase 31 270 3.7E-69 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CXR48_RS18370 d1f41b56896ecccc30086d080a7520f2 276 Gene3D G3DSA:3.40.1190.20 1 276 2.1E-48 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS06885 d1af9a2c3e70e652dda67f8f5d5e8de8 79 Pfam PF11132 Transcriptional regulator protein (SplA) 3 74 1.0E-38 T 29-03-2018 IPR022608 Transcription regulator SplA CXR48_RS06885 d1af9a2c3e70e652dda67f8f5d5e8de8 79 ProDom PD028055 SPLA TRANSCRIPTIONAL TRANSCRIPTION REGULATOR REGULATION 5 74 5.0E-30 T 29-03-2018 CXR48_RS01365 176fb0ffdf3296ab75d4c0324738de00 430 SMART SM00387 311 422 1.7E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS01365 176fb0ffdf3296ab75d4c0324738de00 430 SUPERFAMILY SSF55874 277 419 3.27E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS01365 176fb0ffdf3296ab75d4c0324738de00 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 7.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS01365 176fb0ffdf3296ab75d4c0324738de00 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 7.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS01365 176fb0ffdf3296ab75d4c0324738de00 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 7.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS01365 176fb0ffdf3296ab75d4c0324738de00 430 Gene3D G3DSA:3.30.565.10 182 421 9.1E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS01365 176fb0ffdf3296ab75d4c0324738de00 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 318 420 2.5E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS11030 83c7612a901cbe4a5d03c277baf78ca2 124 Gene3D G3DSA:3.40.630.30 2 124 3.2E-14 T 29-03-2018 CXR48_RS11030 83c7612a901cbe4a5d03c277baf78ca2 124 SUPERFAMILY SSF55729 5 96 1.35E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS11030 83c7612a901cbe4a5d03c277baf78ca2 124 Pfam PF00583 Acetyltransferase (GNAT) family 30 112 3.0E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS13180 1941c300253c9039dd817a3704be1403 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 5.7E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS13180 1941c300253c9039dd817a3704be1403 194 Gene3D G3DSA:1.10.10.60 46 67 9.4E-11 T 29-03-2018 CXR48_RS13180 1941c300253c9039dd817a3704be1403 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.2E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS13180 1941c300253c9039dd817a3704be1403 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.2E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS13180 1941c300253c9039dd817a3704be1403 194 Gene3D G3DSA:1.10.357.10 68 194 1.1E-17 T 29-03-2018 CXR48_RS13180 1941c300253c9039dd817a3704be1403 194 SUPERFAMILY SSF48498 78 191 1.2E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS13180 1941c300253c9039dd817a3704be1403 194 Pfam PF08359 YsiA-like protein, C-terminal region 58 190 6.1E-61 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CXR48_RS13180 1941c300253c9039dd817a3704be1403 194 SUPERFAMILY SSF46689 7 82 2.23E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS13180 1941c300253c9039dd817a3704be1403 194 Gene3D G3DSA:1.10.10.60 2 45 3.1E-15 T 29-03-2018 CXR48_RS13270 36e8ab9b1de4c04eac31b8eb92b03763 275 SUPERFAMILY SSF161098 5 275 4.39E-65 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS13270 36e8ab9b1de4c04eac31b8eb92b03763 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 266 1.7E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS13270 36e8ab9b1de4c04eac31b8eb92b03763 275 Gene3D G3DSA:1.10.3720.10 2 262 7.9E-39 T 29-03-2018 CXR48_RS01260 5ce309f3416cc31c5b5bf311e341bdc3 444 ProSitePatterns PS00942 glpT family of transporters signature. 153 169 - T 29-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 CXR48_RS01260 5ce309f3416cc31c5b5bf311e341bdc3 444 Gene3D G3DSA:1.20.1250.20 240 443 5.1E-28 T 29-03-2018 CXR48_RS01260 5ce309f3416cc31c5b5bf311e341bdc3 444 Pfam PF07690 Major Facilitator Superfamily 34 399 1.2E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS01260 5ce309f3416cc31c5b5bf311e341bdc3 444 SUPERFAMILY SSF103473 9 436 4.84E-82 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS01260 5ce309f3416cc31c5b5bf311e341bdc3 444 PIRSF PIRSF002808 5 444 7.8E-177 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CXR48_RS01260 5ce309f3416cc31c5b5bf311e341bdc3 444 Gene3D G3DSA:1.20.1250.20 18 222 1.9E-32 T 29-03-2018 CXR48_RS01260 5ce309f3416cc31c5b5bf311e341bdc3 444 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 1 440 7.9E-258 T 29-03-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 CXR48_RS01260 5ce309f3416cc31c5b5bf311e341bdc3 444 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 417 2.1E-168 T 29-03-2018 CXR48_RS01535 65348d1f9fbe6c058d0caf47e8931d89 279 Pfam PF00950 ABC 3 transport family 6 262 3.1E-81 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CXR48_RS01535 65348d1f9fbe6c058d0caf47e8931d89 279 SUPERFAMILY SSF81345 3 257 2.48E-35 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS01535 65348d1f9fbe6c058d0caf47e8931d89 279 Gene3D G3DSA:1.10.3470.10 2 266 1.4E-21 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS06055 7dad3b209347660a511a831eb6d7d5d5 327 Pfam PF13536 Putative multidrug resistance efflux transporter 38 305 5.1E-106 T 29-03-2018 IPR032713 Putative multidrug resistance efflux transporter CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 SUPERFAMILY SSF50621 245 385 3.42E-45 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 PRINTS PR00992 Alanine racemase signature 305 322 1.6E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 PRINTS PR00992 Alanine racemase signature 208 235 1.6E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 PRINTS PR00992 Alanine racemase signature 284 299 1.6E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 PRINTS PR00992 Alanine racemase signature 360 373 1.6E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 PRINTS PR00992 Alanine racemase signature 130 142 1.6E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 PRINTS PR00992 Alanine racemase signature 267 282 1.6E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 PRINTS PR00992 Alanine racemase signature 67 85 1.6E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 PRINTS PR00992 Alanine racemase signature 165 176 1.6E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 PRINTS PR00992 Alanine racemase signature 31 47 1.6E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 Pfam PF01168 Alanine racemase, N-terminal domain 12 235 1.5E-64 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 SMART SM01005 250 378 3.5E-56 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 TIGRFAM TIGR00492 alr: alanine racemase 6 378 1.6E-143 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 Pfam PF00842 Alanine racemase, C-terminal domain 250 377 5.6E-39 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 Hamap MF_01201 Alanine racemase. 5 378 34.291 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 Gene3D G3DSA:2.40.37.10 220 387 7.9E-57 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 Gene3D G3DSA:3.20.20.10 8 219 1.9E-47 T 29-03-2018 IPR029066 PLP-binding barrel CXR48_RS11625 652e2db86b4d0510beecbe9aa38fcea4 393 SUPERFAMILY SSF51419 12 250 2.62E-63 T 29-03-2018 IPR029066 PLP-binding barrel CXR48_RS15280 4cbbe166daa9a976ed8f3ce2fe21127a 261 SMART SM00382 30 225 6.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS15280 4cbbe166daa9a976ed8f3ce2fe21127a 261 Pfam PF00005 ABC transporter 21 173 2.2E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15280 4cbbe166daa9a976ed8f3ce2fe21127a 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 246 9.4E-114 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CXR48_RS15280 4cbbe166daa9a976ed8f3ce2fe21127a 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS15280 4cbbe166daa9a976ed8f3ce2fe21127a 261 Gene3D G3DSA:3.40.50.300 3 251 8.9E-43 T 29-03-2018 CXR48_RS15280 4cbbe166daa9a976ed8f3ce2fe21127a 261 SUPERFAMILY SSF52540 6 232 1.08E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01355 9fc4b8725ab2d649da1a8d1c82cb0b9f 478 PRINTS PR00175 Sodium/alanine symporter signature 182 200 7.9E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS01355 9fc4b8725ab2d649da1a8d1c82cb0b9f 478 PRINTS PR00175 Sodium/alanine symporter signature 346 368 7.9E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS01355 9fc4b8725ab2d649da1a8d1c82cb0b9f 478 PRINTS PR00175 Sodium/alanine symporter signature 301 319 7.9E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS01355 9fc4b8725ab2d649da1a8d1c82cb0b9f 478 PRINTS PR00175 Sodium/alanine symporter signature 210 229 7.9E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS01355 9fc4b8725ab2d649da1a8d1c82cb0b9f 478 PRINTS PR00175 Sodium/alanine symporter signature 406 426 7.9E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS01355 9fc4b8725ab2d649da1a8d1c82cb0b9f 478 PRINTS PR00175 Sodium/alanine symporter signature 92 114 7.9E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS01355 9fc4b8725ab2d649da1a8d1c82cb0b9f 478 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 437 1.4E-154 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS01355 9fc4b8725ab2d649da1a8d1c82cb0b9f 478 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS01355 9fc4b8725ab2d649da1a8d1c82cb0b9f 478 Pfam PF01235 Sodium:alanine symporter family 58 449 2.2E-158 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS14095 98676171e2f9dbdbc50501df389e618c 193 Pfam PF06962 Putative rRNA methylase 48 187 9.4E-49 T 29-03-2018 IPR010719 Putative rRNA methylase CXR48_RS14095 98676171e2f9dbdbc50501df389e618c 193 Gene3D G3DSA:3.40.50.150 7 193 2.7E-21 T 29-03-2018 CXR48_RS14095 98676171e2f9dbdbc50501df389e618c 193 SUPERFAMILY SSF53335 16 154 1.51E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS07600 ef0d9775844d8526f01eba69e375b230 262 Pfam PF08478 POTRA domain, FtsQ-type 54 123 1.1E-18 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type CXR48_RS07600 ef0d9775844d8526f01eba69e375b230 262 Gene3D G3DSA:3.10.20.310 52 225 0.0013 T 29-03-2018 CXR48_RS07600 ef0d9775844d8526f01eba69e375b230 262 Pfam PF03799 Cell division protein FtsQ 127 235 4.5E-9 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB CXR48_RS07600 ef0d9775844d8526f01eba69e375b230 262 Hamap MF_00912 Cell division protein DivIB [divIB]. 13 258 30.694 T 29-03-2018 IPR026580 Cell division protein DivIB CXR48_RS00945 dea84be33c5ff21865880d6212fe9a9a 198 PIRSF PIRSF029886 1 198 5.5E-81 T 29-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 CXR48_RS00945 dea84be33c5ff21865880d6212fe9a9a 198 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 195 2.5E-73 T 29-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 CXR48_RS00945 dea84be33c5ff21865880d6212fe9a9a 198 SMART SM01251 17 196 2.8E-110 T 29-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 CXR48_RS08145 3a5476186ee33cd1d6ecc662753bf563 120 SUPERFAMILY SSF52172 4 119 3.27E-41 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS08145 3a5476186ee33cd1d6ecc662753bf563 120 SMART SM00448 3 115 4.1E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS08145 3a5476186ee33cd1d6ecc662753bf563 120 Gene3D G3DSA:3.40.50.2300 2 120 2.9E-41 T 29-03-2018 CXR48_RS08145 3a5476186ee33cd1d6ecc662753bf563 120 Pfam PF00072 Response regulator receiver domain 5 116 8.0E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS06555 039fe9d8562d86fce442b1bdcd36567e 223 SMART SM00100 21 132 1.2E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CXR48_RS06555 039fe9d8562d86fce442b1bdcd36567e 223 Gene3D G3DSA:2.60.120.10 11 154 3.7E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS06555 039fe9d8562d86fce442b1bdcd36567e 223 SUPERFAMILY SSF51206 27 141 2.88E-24 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CXR48_RS06555 039fe9d8562d86fce442b1bdcd36567e 223 Pfam PF00027 Cyclic nucleotide-binding domain 33 109 3.3E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CXR48_RS06555 039fe9d8562d86fce442b1bdcd36567e 223 Gene3D G3DSA:1.10.10.10 155 223 2.5E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09845 99605dce0cd9a867d85cd4f59cefea9e 383 Pfam PF02333 Phytase 5 380 6.7E-191 T 29-03-2018 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 CXR48_RS09845 99605dce0cd9a867d85cd4f59cefea9e 383 SUPERFAMILY SSF50956 31 379 9.55E-97 T 29-03-2018 CXR48_RS09845 99605dce0cd9a867d85cd4f59cefea9e 383 Gene3D G3DSA:2.120.10.30 29 383 3.8E-71 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CXR48_RS02570 72e23c7d8a67c465a2816b1224be8e3e 147 Pfam PF02082 Transcriptional regulator 1 81 4.2E-20 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CXR48_RS02570 72e23c7d8a67c465a2816b1224be8e3e 147 SUPERFAMILY SSF46785 3 137 3.06E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02570 72e23c7d8a67c465a2816b1224be8e3e 147 Gene3D G3DSA:1.10.10.10 1 147 2.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS11725 3768f81ad738a589b451f88465d5f573 68 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 61 1.1E-15 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CXR48_RS11725 3768f81ad738a589b451f88465d5f573 68 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 2.7E-32 T 29-03-2018 IPR009570 Stage III sporulation protein AC CXR48_RS15955 e48a68c5afe644972e1fb5472e84ceb3 153 Gene3D G3DSA:3.40.630.30 1 153 1.2E-26 T 29-03-2018 CXR48_RS15955 e48a68c5afe644972e1fb5472e84ceb3 153 SUPERFAMILY SSF55729 14 152 3.43E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS15955 e48a68c5afe644972e1fb5472e84ceb3 153 Pfam PF00583 Acetyltransferase (GNAT) family 29 118 5.8E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS17380 efb09e732da2f31e2d7301ee1b713244 246 Gene3D G3DSA:3.30.360.40 176 246 4.9E-26 T 29-03-2018 CXR48_RS17380 efb09e732da2f31e2d7301ee1b713244 246 SUPERFAMILY SSF143842 32 244 2.22E-72 T 29-03-2018 IPR014794 TATA-box binding CXR48_RS17380 efb09e732da2f31e2d7301ee1b713244 246 Gene3D G3DSA:3.30.2030.10 33 169 5.6E-41 T 29-03-2018 CXR48_RS17380 efb09e732da2f31e2d7301ee1b713244 246 Pfam PF08680 TATA-box binding 48 246 3.5E-57 T 29-03-2018 IPR014794 TATA-box binding CXR48_RS13385 fdfb72b0d55c09d753e379aa97acea7f 213 Pfam PF09335 SNARE associated Golgi protein 61 174 5.0E-21 T 29-03-2018 IPR032816 SNARE associated Golgi protein CXR48_RS17550 c2c66287864f493709c48897350fca50 212 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 203 3.3E-57 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CXR48_RS17550 c2c66287864f493709c48897350fca50 212 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CXR48_RS17550 c2c66287864f493709c48897350fca50 212 SUPERFAMILY SSF51569 1 212 2.2E-76 T 29-03-2018 CXR48_RS17550 c2c66287864f493709c48897350fca50 212 Gene3D G3DSA:3.20.20.70 1 212 1.1E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS17550 c2c66287864f493709c48897350fca50 212 ProSitePatterns PS00958 Transaldolase active site. 81 98 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CXR48_RS17550 c2c66287864f493709c48897350fca50 212 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 8.3E-106 T 29-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CXR48_RS17550 c2c66287864f493709c48897350fca50 212 Hamap MF_00494 Probable transaldolase [tal]. 1 211 45.911 T 29-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CXR48_RS07915 f3afe853bf6ea604e1d82964e10d2ac1 188 Gene3D G3DSA:3.10.129.10 61 188 1.4E-19 T 29-03-2018 CXR48_RS07915 f3afe853bf6ea604e1d82964e10d2ac1 188 Hamap MF_01814 Transcription factor FapR [fapR]. 1 188 39.002 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CXR48_RS07915 f3afe853bf6ea604e1d82964e10d2ac1 188 SUPERFAMILY SSF54637 74 182 1.26E-26 T 29-03-2018 IPR029069 HotDog domain CXR48_RS07915 f3afe853bf6ea604e1d82964e10d2ac1 188 PIRSF PIRSF037733 1 188 2.2E-85 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CXR48_RS07915 f3afe853bf6ea604e1d82964e10d2ac1 188 Gene3D G3DSA:1.10.10.10 1 60 1.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07915 f3afe853bf6ea604e1d82964e10d2ac1 188 Pfam PF03061 Thioesterase superfamily 108 166 6.5E-5 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CXR48_RS08285 f4f72b0034a1dceb2a5293a49ea68b64 91 Gene3D G3DSA:3.30.1230.10 1 91 3.0E-30 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CXR48_RS08285 f4f72b0034a1dceb2a5293a49ea68b64 91 SUPERFAMILY SSF64376 5 88 5.62E-28 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CXR48_RS08285 f4f72b0034a1dceb2a5293a49ea68b64 91 Pfam PF04296 Protein of unknown function (DUF448) 10 82 2.6E-28 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CXR48_RS15910 bf4152b8004f641b696fef4a9e9c778c 177 Gene3D G3DSA:1.10.10.10 2 169 4.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15910 bf4152b8004f641b696fef4a9e9c778c 177 SUPERFAMILY SSF46785 7 159 8.35E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15910 bf4152b8004f641b696fef4a9e9c778c 177 PIRSF PIRSF006707 2 177 1.4E-50 T 29-03-2018 IPR026282 DNA-binding protein, MJ1563 type CXR48_RS00275 725b067e0dfbdb0df8bf0f5126c997a6 293 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 21 289 55.891 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CXR48_RS00275 725b067e0dfbdb0df8bf0f5126c997a6 293 Pfam PF00398 Ribosomal RNA adenine dimethylase 21 281 1.7E-85 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CXR48_RS00275 725b067e0dfbdb0df8bf0f5126c997a6 293 Gene3D G3DSA:1.10.8.100 223 288 4.2E-20 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CXR48_RS00275 725b067e0dfbdb0df8bf0f5126c997a6 293 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 53 80 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CXR48_RS00275 725b067e0dfbdb0df8bf0f5126c997a6 293 Gene3D G3DSA:3.40.50.150 2 222 3.6E-60 T 29-03-2018 CXR48_RS00275 725b067e0dfbdb0df8bf0f5126c997a6 293 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 21 287 7.0E-89 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CXR48_RS00275 725b067e0dfbdb0df8bf0f5126c997a6 293 SMART SM00650 37 213 2.6E-85 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CXR48_RS00275 725b067e0dfbdb0df8bf0f5126c997a6 293 SUPERFAMILY SSF53335 17 291 9.21E-74 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS15835 d5890c16543b8801151f2192c7b594c7 248 PIRSF PIRSF017388 3 248 4.2E-99 T 29-03-2018 IPR012354 Esterase/lipase GO:0052689 CXR48_RS15835 d5890c16543b8801151f2192c7b594c7 248 Gene3D G3DSA:3.40.50.1820 2 248 7.1E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS15835 d5890c16543b8801151f2192c7b594c7 248 Pfam PF12146 Serine aminopeptidase, S33 18 231 2.2E-18 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CXR48_RS15835 d5890c16543b8801151f2192c7b594c7 248 SUPERFAMILY SSF53474 13 247 4.91E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS06000 5f0e88a09d27174a6990a21af16af847 57 Pfam PF14070 Putative motility protein 3 56 6.4E-12 T 29-03-2018 IPR025906 Putative motility protein CXR48_RS08465 980c29e1c4312fe29ae7f7f75fa1ad4d 264 SUPERFAMILY SSF56300 1 256 1.11E-94 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS08465 980c29e1c4312fe29ae7f7f75fa1ad4d 264 Gene3D G3DSA:3.60.21.10 1 264 2.3E-53 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CXR48_RS08465 980c29e1c4312fe29ae7f7f75fa1ad4d 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 264 3.9E-129 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CXR48_RS08465 980c29e1c4312fe29ae7f7f75fa1ad4d 264 Pfam PF13277 YmdB-like protein 4 254 9.3E-115 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CXR48_RS08465 980c29e1c4312fe29ae7f7f75fa1ad4d 264 PIRSF PIRSF004789 1 263 5.2E-111 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CXR48_RS16340 2e32342ea0a7685b04bb0aeb31bad2dd 197 Pfam PF00484 Carbonic anhydrase 38 181 7.4E-18 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CXR48_RS16340 2e32342ea0a7685b04bb0aeb31bad2dd 197 SUPERFAMILY SSF53056 7 185 1.06E-41 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CXR48_RS16340 2e32342ea0a7685b04bb0aeb31bad2dd 197 Gene3D G3DSA:3.40.1050.10 3 186 1.2E-34 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CXR48_RS16340 2e32342ea0a7685b04bb0aeb31bad2dd 197 SMART SM00947 30 186 7.9E-36 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CXR48_RS02685 87d0debd0595865fabad57f03fa96f9a 113 Pfam PF06486 Protein of unknown function (DUF1093) 30 85 3.3E-10 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CXR48_RS02685 87d0debd0595865fabad57f03fa96f9a 113 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 13 106 6.2E-9 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CXR48_RS02685 87d0debd0595865fabad57f03fa96f9a 113 SUPERFAMILY SSF159121 30 111 1.57E-15 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CXR48_RS00230 e167384cd749f3293a42ab382d9e5692 119 PIRSF PIRSF021439 1 119 4.9E-41 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CXR48_RS00230 e167384cd749f3293a42ab382d9e5692 119 Gene3D G3DSA:1.20.5.10 41 89 0.044 T 29-03-2018 CXR48_RS00230 e167384cd749f3293a42ab382d9e5692 119 Gene3D G3DSA:1.20.5.10 5 40 0.0064 T 29-03-2018 CXR48_RS00230 e167384cd749f3293a42ab382d9e5692 119 Pfam PF06156 Initiation control protein YabA 1 114 4.9E-38 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CXR48_RS00230 e167384cd749f3293a42ab382d9e5692 119 Hamap MF_01159 Initiation-control protein YabA. 1 118 25.01 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CXR48_RS17770 047f4885fd052c050acdce343e5c63ea 74 Pfam PF07293 Protein of unknown function (DUF1450) 7 73 6.5E-10 T 29-03-2018 IPR009910 Protein of unknown function DUF1450 CXR48_RS17770 047f4885fd052c050acdce343e5c63ea 74 Hamap MF_01863 UPF0741 protein . 1 74 33.318 T 29-03-2018 IPR020880 Protein of unknown function UPF0741 CXR48_RS13110 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 1.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS13110 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 1.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS13110 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 1.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS13110 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 Gene3D G3DSA:1.10.10.10 11 72 2.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13110 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 ProSitePatterns PS00622 LuxR-type HTH domain signature. 26 53 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS13110 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 64 3.4E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS13110 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 SMART SM00421 9 66 3.9E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CXR48_RS13110 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 SUPERFAMILY SSF46894 8 72 3.74E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS06360 a248822c4d785891f94f2c70ffdcef6e 87 Pfam PF10779 Haemolysin XhlA 9 72 1.5E-17 T 29-03-2018 IPR019715 Haemolysin XhlA CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 Pfam PF09369 Domain of unknown function (DUF1998) 649 728 2.9E-19 T 29-03-2018 IPR018973 DEAD/DEAH-box helicase, putative CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 SUPERFAMILY SSF52540 69 124 5.32E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 SUPERFAMILY SSF52540 305 446 5.32E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 Gene3D G3DSA:3.40.50.300 268 412 7.9E-20 T 29-03-2018 CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 Gene3D G3DSA:3.40.50.300 19 247 1.2E-33 T 29-03-2018 CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 SMART SM00487 51 255 1.4E-32 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 Pfam PF00271 Helicase conserved C-terminal domain 285 388 3.3E-13 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 SUPERFAMILY SSF52540 36 240 8.65E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 SMART SM00490 302 389 5.6E-14 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS10520 8af2eff288c9838585041658309f8e50 748 Pfam PF00270 DEAD/DEAH box helicase 58 226 1.1E-27 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CXR48_RS09175 e70167435fa142c7f2b150d35caab065 297 Gene3D G3DSA:3.90.550.10 1 292 3.0E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS09175 e70167435fa142c7f2b150d35caab065 297 SUPERFAMILY SSF53448 2 267 1.48E-67 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS09175 e70167435fa142c7f2b150d35caab065 297 Pfam PF00483 Nucleotidyl transferase 7 243 1.4E-32 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CXR48_RS09175 e70167435fa142c7f2b150d35caab065 297 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 265 2.5E-118 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CXR48_RS17845 38f3141002b60f8e63dbc2ee44d21691 236 Pfam PF07883 Cupin domain 151 215 1.6E-8 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CXR48_RS17845 38f3141002b60f8e63dbc2ee44d21691 236 Pfam PF07883 Cupin domain 40 106 5.2E-11 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CXR48_RS17845 38f3141002b60f8e63dbc2ee44d21691 236 SUPERFAMILY SSF51182 5 224 1.4E-29 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS17845 38f3141002b60f8e63dbc2ee44d21691 236 Gene3D G3DSA:2.60.120.10 15 117 3.5E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS17845 38f3141002b60f8e63dbc2ee44d21691 236 Gene3D G3DSA:2.60.120.10 118 225 8.1E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS12150 4c625ef294ecb82a8deb329ae0e81e82 136 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 103 1.0E-18 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CXR48_RS12150 4c625ef294ecb82a8deb329ae0e81e82 136 Gene3D G3DSA:3.40.140.10 1 133 7.8E-54 T 29-03-2018 CXR48_RS12150 4c625ef294ecb82a8deb329ae0e81e82 136 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CXR48_RS12150 4c625ef294ecb82a8deb329ae0e81e82 136 SUPERFAMILY SSF53927 2 130 1.05E-48 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CXR48_RS12150 4c625ef294ecb82a8deb329ae0e81e82 136 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 9.7E-47 T 29-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CXR48_RS01415 0cb7b63cce7f6c20ed084ce654307ccc 127 Pfam PF10710 Protein of unknown function (DUF2512) 1 116 4.1E-37 T 29-03-2018 IPR019649 Protein of unknown function DUF2512 CXR48_RS15940 5ca2443def7eeb26a657913fb730ac26 210 Pfam PF01914 MarC family integral membrane protein 2 205 1.1E-72 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CXR48_RS15940 5ca2443def7eeb26a657913fb730ac26 210 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 2 201 4.3E-80 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CXR48_RS03610 adb208e92d9c82a0ea21350bc8fea7de 485 Gene3D G3DSA:3.40.309.10 269 459 1.0E-66 T 29-03-2018 CXR48_RS03610 adb208e92d9c82a0ea21350bc8fea7de 485 Gene3D G3DSA:3.40.605.10 3 268 4.0E-78 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS03610 adb208e92d9c82a0ea21350bc8fea7de 485 SUPERFAMILY SSF53720 6 478 2.23E-148 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CXR48_RS03610 adb208e92d9c82a0ea21350bc8fea7de 485 Pfam PF00171 Aldehyde dehydrogenase family 16 474 4.7E-154 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CXR48_RS03610 adb208e92d9c82a0ea21350bc8fea7de 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.4E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.4E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.4E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.4E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.4E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 SUPERFAMILY SSF51735 1 248 1.15E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 PIRSF PIRSF000126 4 257 5.5E-51 T 29-03-2018 CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 Pfam PF00106 short chain dehydrogenase 7 190 1.5E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CXR48_RS11300 237a2f9e847fabcc6ac8f0577a0af912 258 Gene3D G3DSA:3.40.50.720 1 258 2.8E-59 T 29-03-2018 CXR48_RS09200 9763f0bc63a8abda3f4b4bc510b89abf 70 Pfam PF00364 Biotin-requiring enzyme 7 69 6.8E-18 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CXR48_RS09200 9763f0bc63a8abda3f4b4bc510b89abf 70 SUPERFAMILY SSF51230 4 69 6.02E-20 T 29-03-2018 IPR011053 Single hybrid motif CXR48_RS09200 9763f0bc63a8abda3f4b4bc510b89abf 70 Gene3D G3DSA:2.40.50.100 1 70 8.3E-18 T 29-03-2018 CXR48_RS10305 901b7d4140dc381ea874e32aaa412648 208 Gene3D G3DSA:3.20.16.10 22 192 3.2E-21 T 29-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CXR48_RS10305 901b7d4140dc381ea874e32aaa412648 208 Pfam PF04586 Caudovirus prohead serine protease 12 185 2.1E-38 T 29-03-2018 IPR006433 Prohead protease CXR48_RS10305 901b7d4140dc381ea874e32aaa412648 208 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 26 173 3.2E-20 T 29-03-2018 IPR006433 Prohead protease CXR48_RS09615 944239101f8cc0b0086b6ae2fd60d990 453 Pfam PF01554 MatE 20 180 6.6E-34 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS09615 944239101f8cc0b0086b6ae2fd60d990 453 Pfam PF01554 MatE 247 407 4.7E-37 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS09615 944239101f8cc0b0086b6ae2fd60d990 453 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 2.0E-108 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS09615 944239101f8cc0b0086b6ae2fd60d990 453 PIRSF PIRSF006603 2 452 1.9E-64 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS04395 745d0db42822e8bc128c16d3b31880f0 255 SUPERFAMILY SSF52540 17 234 2.26E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS04395 745d0db42822e8bc128c16d3b31880f0 255 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS04395 745d0db42822e8bc128c16d3b31880f0 255 Gene3D G3DSA:3.40.50.300 1 240 2.6E-57 T 29-03-2018 CXR48_RS04395 745d0db42822e8bc128c16d3b31880f0 255 SMART SM00382 31 221 2.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS04395 745d0db42822e8bc128c16d3b31880f0 255 Pfam PF00005 ABC transporter 22 158 1.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS07050 51bf28e4b153cdf0b4966f9e2c7f3680 200 Pfam PF12804 MobA-like NTP transferase domain 6 143 1.4E-22 T 29-03-2018 IPR025877 MobA-like NTP transferase CXR48_RS07050 51bf28e4b153cdf0b4966f9e2c7f3680 200 SUPERFAMILY SSF53448 6 187 4.73E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS07050 51bf28e4b153cdf0b4966f9e2c7f3680 200 Gene3D G3DSA:3.90.550.10 2 200 5.1E-18 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS07050 51bf28e4b153cdf0b4966f9e2c7f3680 200 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 190 21.717 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CXR48_RS09455 d8caff7fb7ec0f8f811129eaea3546d1 178 Pfam PF04238 Protein of unknown function (DUF420) 46 174 2.9E-46 T 29-03-2018 IPR007352 Protein of unknown function DUF420 CXR48_RS09455 d8caff7fb7ec0f8f811129eaea3546d1 178 Gene3D G3DSA:1.20.120.80 4 177 2.8E-12 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS13605 9be2e0fc453d16f9a0515c90221c4202 229 Pfam PF11167 Protein of unknown function (DUF2953) 129 182 9.9E-17 T 29-03-2018 IPR021338 Protein of unknown function DUF2953 CXR48_RS17270 ab0c95ff730e198886b6925bc43346f5 140 Pfam PF04892 VanZ like family 5 125 4.5E-12 T 29-03-2018 IPR006976 VanZ-like CXR48_RS07410 dd189bc2930f60665387f89b5304a238 308 Pfam PF02628 Cytochrome oxidase assembly protein 53 289 8.9E-29 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CXR48_RS07410 dd189bc2930f60665387f89b5304a238 308 Hamap MF_01664 Heme A synthase [ctaA]. 1 304 28.709 T 29-03-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 CXR48_RS19425 91fe843a0f31770fecfe7411c1c6ee44 259 PRINTS PR00701 60kDa inner membrane protein signature 124 147 1.6E-15 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CXR48_RS19425 91fe843a0f31770fecfe7411c1c6ee44 259 PRINTS PR00701 60kDa inner membrane protein signature 208 231 1.6E-15 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CXR48_RS19425 91fe843a0f31770fecfe7411c1c6ee44 259 PRINTS PR01900 YidC translocation/secretion protein signature 197 221 8.5E-6 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CXR48_RS19425 91fe843a0f31770fecfe7411c1c6ee44 259 PRINTS PR01900 YidC translocation/secretion protein signature 175 190 8.5E-6 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CXR48_RS19425 91fe843a0f31770fecfe7411c1c6ee44 259 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 246 32.593 T 29-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CXR48_RS19425 91fe843a0f31770fecfe7411c1c6ee44 259 Pfam PF02096 60Kd inner membrane protein 59 241 6.7E-62 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CXR48_RS19425 91fe843a0f31770fecfe7411c1c6ee44 259 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 58 241 2.1E-68 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CXR48_RS15565 45c0875747e70c29e06b9da935280240 178 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 168 2.3E-17 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS15565 45c0875747e70c29e06b9da935280240 178 Pfam PF04545 Sigma-70, region 4 117 166 7.3E-14 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS15565 45c0875747e70c29e06b9da935280240 178 SUPERFAMILY SSF88659 105 170 2.8E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS15565 45c0875747e70c29e06b9da935280240 178 Gene3D G3DSA:1.10.10.10 98 178 4.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07555 476c02ca7b27d69af1cb5b6fd6ad9d4a 117 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 34 116 4.0E-22 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CXR48_RS07555 476c02ca7b27d69af1cb5b6fd6ad9d4a 117 Hamap MF_00910 Cell division protein FtsL [ftsL]. 34 116 13.592 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CXR48_RS07555 476c02ca7b27d69af1cb5b6fd6ad9d4a 117 Gene3D G3DSA:1.20.5.50 61 93 0.0025 T 29-03-2018 CXR48_RS00250 3fc0fede37df32c89d8cd7215c3f7a43 94 SMART SM00966 8 51 6.6E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS00250 3fc0fede37df32c89d8cd7215c3f7a43 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 4.6E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS00250 3fc0fede37df32c89d8cd7215c3f7a43 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 8.8E-12 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS00250 3fc0fede37df32c89d8cd7215c3f7a43 94 Gene3D G3DSA:2.10.260.10 1 48 9.0E-21 T 29-03-2018 CXR48_RS00250 3fc0fede37df32c89d8cd7215c3f7a43 94 SUPERFAMILY SSF89447 1 52 1.23E-16 T 29-03-2018 CXR48_RS06125 8537f699c672d84c18408193ca09ff26 416 Gene3D G3DSA:3.30.565.10 281 416 5.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06125 8537f699c672d84c18408193ca09ff26 416 SUPERFAMILY SSF55874 301 411 1.02E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS06125 8537f699c672d84c18408193ca09ff26 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 373 1.0E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS13720 39585dd6811784d015762480180a1868 169 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 169 5.3E-56 T 29-03-2018 IPR006286 Peptidase C56, PfpI CXR48_RS13720 39585dd6811784d015762480180a1868 169 Pfam PF01965 DJ-1/PfpI family 3 165 2.4E-55 T 29-03-2018 IPR002818 DJ-1/PfpI CXR48_RS13720 39585dd6811784d015762480180a1868 169 Gene3D G3DSA:3.40.50.880 1 168 1.4E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS13720 39585dd6811784d015762480180a1868 169 SUPERFAMILY SSF52317 1 168 3.55E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS17870 2b98d1af5efe5fdd4985aa47cbd5ba9b 560 Pfam PF01546 Peptidase family M20/M25/M40 131 203 2.3E-8 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS17870 2b98d1af5efe5fdd4985aa47cbd5ba9b 560 Gene3D G3DSA:3.40.630.10 6 548 3.2E-30 T 29-03-2018 CXR48_RS17870 2b98d1af5efe5fdd4985aa47cbd5ba9b 560 SUPERFAMILY SSF53187 477 529 6.02E-28 T 29-03-2018 CXR48_RS17870 2b98d1af5efe5fdd4985aa47cbd5ba9b 560 SUPERFAMILY SSF53187 137 242 6.02E-28 T 29-03-2018 CXR48_RS17870 2b98d1af5efe5fdd4985aa47cbd5ba9b 560 SUPERFAMILY SSF53187 4 103 6.02E-28 T 29-03-2018 CXR48_RS17870 2b98d1af5efe5fdd4985aa47cbd5ba9b 560 PIRSF PIRSF010386 3 556 4.0E-220 T 29-03-2018 IPR012166 Uncharacterised protein family RocB CXR48_RS10905 13408ad973e9eb21e94b82b4625b86c9 152 ProDom PD089241 YPBF MEMBRANE BH1610 TRANSMEMBRANE 17 150 9.0E-53 T 29-03-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane CXR48_RS10905 13408ad973e9eb21e94b82b4625b86c9 152 Pfam PF10864 Protein of unknown function (DUF2663) 19 150 4.1E-48 T 29-03-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane CXR48_RS03720 667d984a9e7a3f51a140c1100b338fc3 226 Gene3D G3DSA:3.40.50.2300 1 142 7.9E-28 T 29-03-2018 CXR48_RS03720 667d984a9e7a3f51a140c1100b338fc3 226 Pfam PF00072 Response regulator receiver domain 4 113 2.2E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS03720 667d984a9e7a3f51a140c1100b338fc3 226 Pfam PF08279 HTH domain 162 199 1.4E-4 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CXR48_RS03720 667d984a9e7a3f51a140c1100b338fc3 226 SUPERFAMILY SSF52172 3 134 7.97E-29 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS03720 667d984a9e7a3f51a140c1100b338fc3 226 PIRSF PIRSF006171 1 226 4.2E-76 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CXR48_RS03720 667d984a9e7a3f51a140c1100b338fc3 226 Gene3D G3DSA:1.10.10.10 160 224 7.5E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03720 667d984a9e7a3f51a140c1100b338fc3 226 SMART SM00448 2 115 4.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS04350 500e117ff04a7f7f13f7b1487ce317dd 451 Pfam PF08031 Berberine and berberine like 400 443 1.5E-19 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CXR48_RS04350 500e117ff04a7f7f13f7b1487ce317dd 451 SUPERFAMILY SSF56176 6 204 1.64E-49 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CXR48_RS04350 500e117ff04a7f7f13f7b1487ce317dd 451 Gene3D G3DSA:3.30.465.10 87 230 7.1E-32 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CXR48_RS04350 500e117ff04a7f7f13f7b1487ce317dd 451 Pfam PF01565 FAD binding domain 33 162 2.3E-29 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CXR48_RS04350 500e117ff04a7f7f13f7b1487ce317dd 451 Gene3D G3DSA:3.30.43.10 8 86 1.4E-19 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CXR48_RS06520 1077e1a4dafc2a4396edb16e20aafbb4 169 Pfam PF01047 MarR family 61 118 3.0E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06520 1077e1a4dafc2a4396edb16e20aafbb4 169 SUPERFAMILY SSF46785 25 166 3.75E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06520 1077e1a4dafc2a4396edb16e20aafbb4 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 6.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06520 1077e1a4dafc2a4396edb16e20aafbb4 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 6.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06520 1077e1a4dafc2a4396edb16e20aafbb4 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 6.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS06520 1077e1a4dafc2a4396edb16e20aafbb4 169 Gene3D G3DSA:1.10.10.10 27 166 1.1E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06520 1077e1a4dafc2a4396edb16e20aafbb4 169 SMART SM00347 53 151 1.8E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS17335 59b6c42de7a24fea0b38b5ed9ae9a455 62 Pfam PF05532 CsbD-like 9 61 2.3E-13 T 29-03-2018 IPR008462 CsbD-like domain CXR48_RS17335 59b6c42de7a24fea0b38b5ed9ae9a455 62 Gene3D G3DSA:1.10.1470.10 7 62 2.2E-11 T 29-03-2018 IPR008462 CsbD-like domain CXR48_RS17335 59b6c42de7a24fea0b38b5ed9ae9a455 62 SUPERFAMILY SSF69047 8 61 1.31E-9 T 29-03-2018 IPR008462 CsbD-like domain CXR48_RS09265 8c190108e977a589fa41a089d25e87a4 322 Gene3D G3DSA:2.70.98.10 1 322 1.2E-71 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CXR48_RS09265 8c190108e977a589fa41a089d25e87a4 322 Pfam PF01263 Aldose 1-epimerase 17 315 6.2E-52 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CXR48_RS09265 8c190108e977a589fa41a089d25e87a4 322 SUPERFAMILY SSF74650 11 315 1.07E-56 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CXR48_RS02970 607cae1ed8b94b55df741c7661b275ab 154 SUPERFAMILY SSF55961 17 150 2.63E-33 T 29-03-2018 CXR48_RS02970 607cae1ed8b94b55df741c7661b275ab 154 Gene3D G3DSA:3.30.530.20 10 154 8.9E-20 T 29-03-2018 IPR023393 START-like domain CXR48_RS02970 607cae1ed8b94b55df741c7661b275ab 154 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 28 149 2.0E-9 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CXR48_RS08955 8ea76ab2a47d83a91d633e843ee5e616 48 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 2 48 19.014 T 29-03-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 CXR48_RS08955 8ea76ab2a47d83a91d633e843ee5e616 48 Pfam PF08177 Small acid-soluble spore protein N family 1 47 4.1E-22 T 29-03-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 CXR48_RS08630 a571b88558609970b88b264d4110090d 104 Pfam PF00893 Small Multidrug Resistance protein 4 94 1.4E-27 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CXR48_RS08630 a571b88558609970b88b264d4110090d 104 SUPERFAMILY SSF103481 7 104 1.44E-17 T 29-03-2018 CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 SUPERFAMILY SSF52467 194 337 1.46E-32 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 542 3.0E-43 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 SUPERFAMILY SSF52518 373 553 1.09E-58 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 SUPERFAMILY SSF52518 13 184 2.7E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 16 553 1.3E-272 T 29-03-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 Gene3D G3DSA:3.40.50.970 361 562 2.2E-38 T 29-03-2018 CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 334 5.3E-26 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 180 3.6E-52 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 Gene3D G3DSA:3.40.50.970 8 203 1.5E-49 T 29-03-2018 CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 433 452 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CXR48_RS16985 dc07b2f02c006c2daa05c7ab9eb091d7 570 Gene3D G3DSA:3.40.50.1220 204 360 1.5E-23 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS09275 64a93a3142d0301b805b6ad08ced35f9 180 Pfam PF16800 IseA DL-endopeptidase inhibitor 28 178 1.4E-51 T 29-03-2018 IPR031841 DL-endopeptidase inhibitor IseA CXR48_RS14045 6cb5e32a391ec74fd2dd572fc242046e 231 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS14045 6cb5e32a391ec74fd2dd572fc242046e 231 Gene3D G3DSA:3.40.50.300 1 230 4.0E-66 T 29-03-2018 CXR48_RS14045 6cb5e32a391ec74fd2dd572fc242046e 231 SUPERFAMILY SSF52540 1 223 5.74E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14045 6cb5e32a391ec74fd2dd572fc242046e 231 Pfam PF00005 ABC transporter 25 173 2.3E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS14045 6cb5e32a391ec74fd2dd572fc242046e 231 SMART SM00382 34 224 6.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS13355 f07a3a9409315ab162aa82513e1ca8e0 244 Pfam PF04397 LytTr DNA-binding domain 146 241 8.8E-30 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CXR48_RS13355 f07a3a9409315ab162aa82513e1ca8e0 244 SMART SM00448 2 113 1.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS13355 f07a3a9409315ab162aa82513e1ca8e0 244 Gene3D G3DSA:2.40.50.40 135 205 2.4E-15 T 29-03-2018 CXR48_RS13355 f07a3a9409315ab162aa82513e1ca8e0 244 Gene3D G3DSA:2.20.25.10 206 242 1.3E-19 T 29-03-2018 CXR48_RS13355 f07a3a9409315ab162aa82513e1ca8e0 244 SUPERFAMILY SSF52172 1 122 3.7E-28 T 29-03-2018 IPR011006 CheY-like superfamily CXR48_RS13355 f07a3a9409315ab162aa82513e1ca8e0 244 Pfam PF00072 Response regulator receiver domain 4 113 9.8E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CXR48_RS13355 f07a3a9409315ab162aa82513e1ca8e0 244 Gene3D G3DSA:3.40.50.2300 1 128 3.4E-26 T 29-03-2018 CXR48_RS13355 f07a3a9409315ab162aa82513e1ca8e0 244 SMART SM00850 145 242 1.4E-36 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 PRINTS PR00154 AMP-binding signature 168 179 6.9E-5 T 29-03-2018 IPR020459 AMP-binding CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 PRINTS PR00154 AMP-binding signature 180 188 6.9E-5 T 29-03-2018 IPR020459 AMP-binding CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 SUPERFAMILY SSF56801 2 511 1.16E-161 T 29-03-2018 CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 Gene3D G3DSA:2.30.38.10 329 411 9.1E-27 T 29-03-2018 CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 Pfam PF00501 AMP-binding enzyme 7 418 1.5E-116 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 501 5.1E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 Gene3D G3DSA:3.40.50.980 179 328 1.5E-52 T 29-03-2018 CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 Gene3D G3DSA:3.40.50.980 2 178 2.7E-42 T 29-03-2018 CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 Gene3D G3DSA:3.30.300.30 412 513 4.3E-31 T 29-03-2018 CXR48_RS05115 cc9a5da3b636dd1243ca6de5da413d2e 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS09745 cc18b6093d1037794ff93da03ab4fcee 203 Gene3D G3DSA:1.20.144.10 4 202 1.2E-25 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CXR48_RS09745 cc18b6093d1037794ff93da03ab4fcee 203 SUPERFAMILY SSF48317 7 199 7.46E-36 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CXR48_RS09745 cc18b6093d1037794ff93da03ab4fcee 203 SMART SM00014 78 191 1.4E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CXR48_RS09745 cc18b6093d1037794ff93da03ab4fcee 203 Pfam PF01569 PAP2 superfamily 89 193 6.9E-21 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CXR48_RS17115 c9b075d135cdf480a22437a64efba47b 144 Gene3D G3DSA:1.20.58.60 3 144 8.9E-6 T 29-03-2018 CXR48_RS17115 c9b075d135cdf480a22437a64efba47b 144 Pfam PF16888 Domain of unknown function (DUF5082) 12 102 3.4E-8 T 29-03-2018 IPR031681 Protein of unknown function DUF5082 CXR48_RS17115 c9b075d135cdf480a22437a64efba47b 144 ProDom PD085159 YWQH COILED COIL 1 138 2.0E-36 T 29-03-2018 IPR020326 Uncharacterised protein family YwqH CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 SMART SM01005 245 370 1.5E-63 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 Hamap MF_01201 Alanine racemase. 7 370 34.66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 Gene3D G3DSA:2.40.37.10 230 379 5.8E-56 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 PRINTS PR00992 Alanine racemase signature 352 365 5.0E-72 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 PRINTS PR00992 Alanine racemase signature 33 49 5.0E-72 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 PRINTS PR00992 Alanine racemase signature 261 276 5.0E-72 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 PRINTS PR00992 Alanine racemase signature 69 87 5.0E-72 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 PRINTS PR00992 Alanine racemase signature 163 174 5.0E-72 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 PRINTS PR00992 Alanine racemase signature 128 140 5.0E-72 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 PRINTS PR00992 Alanine racemase signature 278 293 5.0E-72 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 PRINTS PR00992 Alanine racemase signature 203 230 5.0E-72 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 PRINTS PR00992 Alanine racemase signature 298 315 5.0E-72 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 SUPERFAMILY SSF50621 240 380 4.88E-49 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 SUPERFAMILY SSF51419 14 245 1.55E-66 T 29-03-2018 IPR029066 PLP-binding barrel CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 Pfam PF01168 Alanine racemase, N-terminal domain 14 230 1.7E-68 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 TIGRFAM TIGR00492 alr: alanine racemase 8 370 6.0E-142 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 Gene3D G3DSA:3.20.20.10 1 229 7.9E-49 T 29-03-2018 IPR029066 PLP-binding barrel CXR48_RS02420 05f2dad0fa4f32e202d907c5d6817538 389 Pfam PF00842 Alanine racemase, C-terminal domain 246 368 5.9E-43 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CXR48_RS11600 936b74e823e2d724c1cdcdd8946d8c28 207 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 6 202 1.4E-53 T 29-03-2018 IPR014205 Sporulation protein YtaF CXR48_RS11600 936b74e823e2d724c1cdcdd8946d8c28 207 Pfam PF02659 Putative manganese efflux pump 3 82 3.0E-8 T 29-03-2018 IPR003810 Putative manganese efflux pump CXR48_RS19435 6b28e8f76ddbd446b8e61ad3efd9b3f5 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 2.1E-20 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19435 6b28e8f76ddbd446b8e61ad3efd9b3f5 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 9.0E-8 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19435 6b28e8f76ddbd446b8e61ad3efd9b3f5 44 Pfam PF00468 Ribosomal protein L34 1 44 5.7E-23 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS19435 6b28e8f76ddbd446b8e61ad3efd9b3f5 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS19435 6b28e8f76ddbd446b8e61ad3efd9b3f5 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.77 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS08340 a5fdfcd91241d11e04ae7558c8983d2d 85 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 76 2.7E-28 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH CXR48_RS08340 a5fdfcd91241d11e04ae7558c8983d2d 85 SUPERFAMILY SSF50346 1 75 1.96E-12 T 29-03-2018 IPR011033 PRC-barrel-like CXR48_RS08340 a5fdfcd91241d11e04ae7558c8983d2d 85 Pfam PF05239 PRC-barrel domain 1 79 2.0E-15 T 29-03-2018 IPR027275 PRC-barrel domain CXR48_RS08340 a5fdfcd91241d11e04ae7558c8983d2d 85 Gene3D G3DSA:2.30.30.240 1 79 3.8E-15 T 29-03-2018 CXR48_RS12770 85480aa51ed8120f15fe073adf660ad8 86 Pfam PF02699 Preprotein translocase subunit 6 81 7.2E-32 T 29-03-2018 IPR003849 Preprotein translocase YajC CXR48_RS12770 85480aa51ed8120f15fe073adf660ad8 86 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 83 2.8E-34 T 29-03-2018 IPR003849 Preprotein translocase YajC CXR48_RS12770 85480aa51ed8120f15fe073adf660ad8 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 42 60 3.7E-15 T 29-03-2018 IPR003849 Preprotein translocase YajC CXR48_RS12770 85480aa51ed8120f15fe073adf660ad8 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 3.7E-15 T 29-03-2018 IPR003849 Preprotein translocase YajC CXR48_RS12770 85480aa51ed8120f15fe073adf660ad8 86 SMART SM01323 2 84 2.7E-43 T 29-03-2018 IPR003849 Preprotein translocase YajC CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 Gene3D G3DSA:3.40.1830.10 5 175 3.0E-61 T 29-03-2018 IPR035097 Peptidase M29, N-terminal CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 389 408 2.7E-83 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 2.7E-83 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 2.7E-83 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 2.7E-83 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 2.7E-83 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 2.7E-83 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 363 385 2.7E-83 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 2.7E-83 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 Pfam PF02073 Thermophilic metalloprotease (M29) 5 408 1.2E-178 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CXR48_RS07135 003e8d3bf53731d3c7abc020f2fc313f 410 SUPERFAMILY SSF144052 4 409 8.63E-155 T 29-03-2018 CXR48_RS02760 55df37b26a9cf22442edb9614d93bf28 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS02760 55df37b26a9cf22442edb9614d93bf28 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS02760 55df37b26a9cf22442edb9614d93bf28 192 Pfam PF16859 Bacterial transcriptional repressor C-terminal 74 183 4.1E-29 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS02760 55df37b26a9cf22442edb9614d93bf28 192 SUPERFAMILY SSF48498 78 190 5.34E-25 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS02760 55df37b26a9cf22442edb9614d93bf28 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 59 1.1E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS02760 55df37b26a9cf22442edb9614d93bf28 192 SUPERFAMILY SSF46689 7 65 3.34E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS02760 55df37b26a9cf22442edb9614d93bf28 192 Gene3D G3DSA:1.10.10.60 1 59 3.1E-17 T 29-03-2018 CXR48_RS02760 55df37b26a9cf22442edb9614d93bf28 192 Gene3D G3DSA:1.10.357.10 60 192 1.1E-18 T 29-03-2018 CXR48_RS11765 8982ce98808ffa1ea3b8931de4a7073e 131 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 5 131 2.0E-47 T 29-03-2018 CXR48_RS18110 08768d14576ebb0e7524e6b3b695b239 207 SUPERFAMILY SSF48498 131 201 6.92E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CXR48_RS18110 08768d14576ebb0e7524e6b3b695b239 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS18110 08768d14576ebb0e7524e6b3b695b239 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS18110 08768d14576ebb0e7524e6b3b695b239 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.7E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CXR48_RS18110 08768d14576ebb0e7524e6b3b695b239 207 SUPERFAMILY SSF46689 5 67 1.07E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS18110 08768d14576ebb0e7524e6b3b695b239 207 Gene3D G3DSA:1.10.10.60 6 50 2.4E-14 T 29-03-2018 CXR48_RS18110 08768d14576ebb0e7524e6b3b695b239 207 Gene3D G3DSA:1.10.10.60 51 112 6.2E-10 T 29-03-2018 CXR48_RS05755 2fb66b52b56bdce51b18820b713fa78b 270 Pfam PF08543 Phosphomethylpyrimidine kinase 13 258 1.9E-93 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CXR48_RS05755 2fb66b52b56bdce51b18820b713fa78b 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 260 8.3E-99 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CXR48_RS05755 2fb66b52b56bdce51b18820b713fa78b 270 SUPERFAMILY SSF53613 4 262 1.48E-80 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS05755 2fb66b52b56bdce51b18820b713fa78b 270 Gene3D G3DSA:3.40.1190.20 2 270 2.1E-62 T 29-03-2018 IPR029056 Ribokinase-like CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 Pfam PF00005 ABC transporter 18 168 1.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 Pfam PF00005 ABC transporter 268 421 1.7E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 SUPERFAMILY SSF52540 3 224 1.81E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 Gene3D G3DSA:3.40.50.300 242 489 1.1E-37 T 29-03-2018 CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 ProSitePatterns PS00211 ABC transporters family signature. 394 408 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 Gene3D G3DSA:3.40.50.300 2 231 9.9E-57 T 29-03-2018 CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 SMART SM00382 276 470 3.7E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 SMART SM00382 27 216 7.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS16955 27178b156efbb2fc8e3e97b38da6b3f2 497 SUPERFAMILY SSF52540 239 479 2.44E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS13770 6ffdb74df78b0e84aa78e1b842755ca5 210 Gene3D G3DSA:3.40.630.30 1 210 1.2E-52 T 29-03-2018 CXR48_RS13770 6ffdb74df78b0e84aa78e1b842755ca5 210 PIRSF PIRSF021278 2 210 1.0E-82 T 29-03-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 CXR48_RS13770 6ffdb74df78b0e84aa78e1b842755ca5 210 SUPERFAMILY SSF55729 38 119 2.16E-8 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS13770 6ffdb74df78b0e84aa78e1b842755ca5 210 Pfam PF00583 Acetyltransferase (GNAT) family 45 118 5.7E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS06980 fab98c81c820f3800aaed1bd5761056d 172 Pfam PF04308 Ribonuclease H-like 19 172 2.4E-52 T 29-03-2018 IPR007405 Bacteriophage KVP40, Orf299 CXR48_RS00950 1c7801b97d7abfc8a0fc191ba42c39d1 254 Pfam PF01522 Polysaccharide deacetylase 52 174 8.5E-26 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CXR48_RS00950 1c7801b97d7abfc8a0fc191ba42c39d1 254 SUPERFAMILY SSF88713 26 243 1.06E-51 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CXR48_RS00950 1c7801b97d7abfc8a0fc191ba42c39d1 254 Gene3D G3DSA:3.20.20.370 47 254 5.9E-49 T 29-03-2018 CXR48_RS00950 1c7801b97d7abfc8a0fc191ba42c39d1 254 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 53 243 2.0E-80 T 29-03-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB CXR48_RS04145 d0ba3964b12918ecb13a1056d6c43af6 175 Pfam PF08239 Bacterial SH3 domain 54 104 1.6E-10 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS04145 d0ba3964b12918ecb13a1056d6c43af6 175 SMART SM00287 45 108 5.0E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS04145 d0ba3964b12918ecb13a1056d6c43af6 175 SMART SM00287 115 175 5.0 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS04145 d0ba3964b12918ecb13a1056d6c43af6 175 Gene3D G3DSA:2.30.30.410 28 119 1.0E-13 T 29-03-2018 CXR48_RS04145 d0ba3964b12918ecb13a1056d6c43af6 175 Gene3D G3DSA:2.40.50.110 120 175 1.4E-4 T 29-03-2018 CXR48_RS10815 1daf6ba79707980a3ca9e81bf1f8d414 492 Gene3D G3DSA:3.40.50.300 6 434 1.3E-11 T 29-03-2018 CXR48_RS10815 1daf6ba79707980a3ca9e81bf1f8d414 492 SUPERFAMILY SSF52540 19 226 9.52E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS10815 1daf6ba79707980a3ca9e81bf1f8d414 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 2.2E-272 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CXR48_RS10815 1daf6ba79707980a3ca9e81bf1f8d414 492 PIRSF PIRSF007466 1 492 8.1E-268 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CXR48_RS10815 1daf6ba79707980a3ca9e81bf1f8d414 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 2.1E-226 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CXR48_RS14820 2e45c4b4361acc2d4b16e896a62ebbdb 176 TIGRFAM TIGR00277 HDIG: HDIG domain 22 91 6.0E-8 T 29-03-2018 IPR006675 HDIG domain CXR48_RS14820 2e45c4b4361acc2d4b16e896a62ebbdb 176 SMART SM00471 19 148 1.4E-8 T 29-03-2018 IPR003607 HD/PDEase domain CXR48_RS14820 2e45c4b4361acc2d4b16e896a62ebbdb 176 Gene3D G3DSA:1.10.3210.10 8 170 3.4E-16 T 29-03-2018 CXR48_RS14820 2e45c4b4361acc2d4b16e896a62ebbdb 176 Pfam PF01966 HD domain 25 137 1.0E-14 T 29-03-2018 IPR006674 HD domain CXR48_RS14820 2e45c4b4361acc2d4b16e896a62ebbdb 176 SUPERFAMILY SSF109604 16 137 1.28E-20 T 29-03-2018 CXR48_RS08520 414f1d497c7f0b39d62f141bb9cf200b 225 Gene3D G3DSA:3.60.15.10 1 223 5.0E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS08520 414f1d497c7f0b39d62f141bb9cf200b 225 SMART SM00849 18 181 8.3E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS08520 414f1d497c7f0b39d62f141bb9cf200b 225 Pfam PF00753 Metallo-beta-lactamase superfamily 20 181 2.2E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS08520 414f1d497c7f0b39d62f141bb9cf200b 225 SUPERFAMILY SSF56281 6 210 1.97E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS18455 747c0f481f77488d2f449e1d7830c8c0 224 Gene3D G3DSA:3.90.640.20 144 224 1.7E-12 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CXR48_RS18455 747c0f481f77488d2f449e1d7830c8c0 224 Gene3D G3DSA:3.30.565.40 27 143 5.9E-20 T 29-03-2018 CXR48_RS18455 747c0f481f77488d2f449e1d7830c8c0 224 Pfam PF11738 Protein of unknown function (DUF3298) 171 220 7.4E-6 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CXR48_RS18455 747c0f481f77488d2f449e1d7830c8c0 224 Pfam PF13739 Domain of unknown function (DUF4163) 44 128 4.7E-18 T 29-03-2018 IPR025303 Deacetylase PdaC CXR48_RS11000 1c2db5fe3bec16756655539317d49704 161 Pfam PF13047 Protein of unknown function (DUF3907) 10 152 3.7E-57 T 29-03-2018 IPR025013 Protein of unknown function DUF3907 CXR48_RS02635 9ace5ef3be58f627593359101537a08b 105 Pfam PF03551 Transcriptional regulator PadR-like family 17 82 4.7E-13 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CXR48_RS02635 9ace5ef3be58f627593359101537a08b 105 SUPERFAMILY SSF46785 8 93 3.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02635 9ace5ef3be58f627593359101537a08b 105 Gene3D G3DSA:1.10.10.10 1 94 5.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05360 5716ca661667c6523550f4bcc2c63052 246 Pfam PF00494 Squalene/phytoene synthase 21 242 1.4E-32 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CXR48_RS05360 5716ca661667c6523550f4bcc2c63052 246 SUPERFAMILY SSF48576 4 241 3.31E-34 T 29-03-2018 IPR008949 Isoprenoid synthase domain CXR48_RS05360 5716ca661667c6523550f4bcc2c63052 246 Gene3D G3DSA:1.10.600.10 1 245 2.6E-36 T 29-03-2018 IPR008949 Isoprenoid synthase domain CXR48_RS16315 03de26c506453949997ce4e87c235347 376 Gene3D G3DSA:3.10.310.10 1 174 3.1E-76 T 29-03-2018 CXR48_RS16315 03de26c506453949997ce4e87c235347 376 SUPERFAMILY SSF54506 170 366 1.48E-54 T 29-03-2018 CXR48_RS16315 03de26c506453949997ce4e87c235347 376 Gene3D G3DSA:3.10.310.10 175 351 5.2E-55 T 29-03-2018 CXR48_RS16315 03de26c506453949997ce4e87c235347 376 SUPERFAMILY SSF54506 3 165 2.59E-62 T 29-03-2018 CXR48_RS16315 03de26c506453949997ce4e87c235347 376 Pfam PF04303 PrpF protein 2 364 8.2E-137 T 29-03-2018 IPR007400 PrpF protein CXR48_RS19000 1233379912ae57a1d26d6686c110ca82 69 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 65 8.9E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CXR48_RS19000 1233379912ae57a1d26d6686c110ca82 69 SUPERFAMILY SSF46894 29 66 9.35E-8 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CXR48_RS19000 1233379912ae57a1d26d6686c110ca82 69 Gene3D G3DSA:1.10.10.10 13 69 1.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13740 01870504614dc87d28c0f0c81737eb81 268 Pfam PF11495 Archaeal transcriptional regulator TrmB 109 225 2.3E-5 T 29-03-2018 IPR021586 Transcription regulator TrmB, C-terminal CXR48_RS13740 01870504614dc87d28c0f0c81737eb81 268 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 72 1.0E-22 T 29-03-2018 IPR002831 Transcription regulator TrmB, N-terminal CXR48_RS13740 01870504614dc87d28c0f0c81737eb81 268 Gene3D G3DSA:1.10.10.10 1 135 1.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13740 01870504614dc87d28c0f0c81737eb81 268 SUPERFAMILY SSF46785 2 84 1.46E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS07525 ee18a3f04a4370490469feaaa6bc82b8 191 SUPERFAMILY SSF46689 7 62 4.76E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS07525 ee18a3f04a4370490469feaaa6bc82b8 191 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 4 78 2.5E-44 T 29-03-2018 IPR014243 Transcription factor, RsfA CXR48_RS07525 ee18a3f04a4370490469feaaa6bc82b8 191 Gene3D G3DSA:1.10.10.60 4 67 2.5E-7 T 29-03-2018 CXR48_RS07525 ee18a3f04a4370490469feaaa6bc82b8 191 Gene3D G3DSA:1.20.5.340 68 190 3.1E-5 T 29-03-2018 CXR48_RS07525 ee18a3f04a4370490469feaaa6bc82b8 191 Pfam PF13921 Myb-like DNA-binding domain 9 62 2.6E-5 T 29-03-2018 CXR48_RS05765 90c824c0dc557977c9046e86cf92e6f6 202 Pfam PF14153 Spore coat protein CotO 6 202 1.1E-45 T 29-03-2018 IPR025439 Spore coat protein CotO CXR48_RS15725 5d5fc05deb593a4d13390e7012d6fd5b 223 SUPERFAMILY SSF52833 38 216 3.71E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS15725 5d5fc05deb593a4d13390e7012d6fd5b 223 Pfam PF13462 Thioredoxin 46 217 1.5E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS15725 5d5fc05deb593a4d13390e7012d6fd5b 223 Gene3D G3DSA:3.40.30.10 46 223 4.0E-39 T 29-03-2018 CXR48_RS11780 762239fca7f6cb73b79e0abc1c726195 278 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 3 278 68.696 T 29-03-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CXR48_RS11780 762239fca7f6cb73b79e0abc1c726195 278 Gene3D G3DSA:3.30.930.10 3 278 3.5E-59 T 29-03-2018 CXR48_RS11780 762239fca7f6cb73b79e0abc1c726195 278 SUPERFAMILY SSF55681 5 278 3.23E-70 T 29-03-2018 CXR48_RS11780 762239fca7f6cb73b79e0abc1c726195 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 189 3.3E-31 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CXR48_RS17065 2dee49dc0d02d786b96bc2ebe9bfde72 238 Hamap MF_00801 Endonuclease V [nfi]. 13 233 31.924 T 29-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 CXR48_RS17065 2dee49dc0d02d786b96bc2ebe9bfde72 238 Pfam PF04493 Endonuclease V 26 223 4.3E-59 T 29-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 CXR48_RS16515 3a751800c56feeacba6d6b53a5e87041 119 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 106 1.7E-27 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CXR48_RS03875 792b8555d3abfa9d4ac3db1532c8dba9 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 148 2.2E-44 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CXR48_RS03875 792b8555d3abfa9d4ac3db1532c8dba9 157 SMART SM00226 2 150 8.6E-61 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CXR48_RS03875 792b8555d3abfa9d4ac3db1532c8dba9 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 3.5E-18 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CXR48_RS03875 792b8555d3abfa9d4ac3db1532c8dba9 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 3.5E-18 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CXR48_RS03875 792b8555d3abfa9d4ac3db1532c8dba9 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 3.5E-18 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CXR48_RS03875 792b8555d3abfa9d4ac3db1532c8dba9 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 3.5E-18 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CXR48_RS03875 792b8555d3abfa9d4ac3db1532c8dba9 157 Gene3D G3DSA:3.40.50.2300 1 157 1.3E-50 T 29-03-2018 CXR48_RS03875 792b8555d3abfa9d4ac3db1532c8dba9 157 SUPERFAMILY SSF52788 1 151 1.2E-48 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CXR48_RS05835 8a537ce209e3569918a451eae364b95d 245 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS05835 8a537ce209e3569918a451eae364b95d 245 SMART SM00382 28 210 1.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS05835 8a537ce209e3569918a451eae364b95d 245 Pfam PF00005 ABC transporter 20 162 1.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS05835 8a537ce209e3569918a451eae364b95d 245 Gene3D G3DSA:3.40.50.300 1 236 1.5E-69 T 29-03-2018 CXR48_RS05835 8a537ce209e3569918a451eae364b95d 245 SUPERFAMILY SSF52540 3 224 4.75E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS17225 2a26bca071cb4cd2f31bb11ee7a07f12 137 SUPERFAMILY SSF46785 4 135 2.16E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS17225 2a26bca071cb4cd2f31bb11ee7a07f12 137 SMART SM00347 25 124 1.3E-33 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS17225 2a26bca071cb4cd2f31bb11ee7a07f12 137 Pfam PF01047 MarR family 33 88 5.3E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS17225 2a26bca071cb4cd2f31bb11ee7a07f12 137 Gene3D G3DSA:1.10.10.10 2 137 3.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02845 02a812c8ae9b67eab97d745afd194a69 279 Pfam PF13560 Helix-turn-helix domain 32 88 4.9E-16 T 29-03-2018 CXR48_RS02845 02a812c8ae9b67eab97d745afd194a69 279 SMART SM00530 13 85 2.2E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS02845 02a812c8ae9b67eab97d745afd194a69 279 Gene3D G3DSA:1.10.260.40 4 102 1.7E-13 T 29-03-2018 CXR48_RS02845 02a812c8ae9b67eab97d745afd194a69 279 SUPERFAMILY SSF47413 27 84 1.34E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS03335 82c84b3c8b9dca0db29c3102ba313660 331 Gene3D G3DSA:3.50.90.10 20 331 4.4E-102 T 29-03-2018 IPR023158 YerB-like CXR48_RS03335 82c84b3c8b9dca0db29c3102ba313660 331 SUPERFAMILY SSF159774 35 324 3.79E-95 T 29-03-2018 IPR023158 YerB-like CXR48_RS03335 82c84b3c8b9dca0db29c3102ba313660 331 Pfam PF11258 Protein of unknown function (DUF3048) N-terminal domain 37 179 8.5E-52 T 29-03-2018 IPR021416 Protein of unknown function DUF3048, N-terminal CXR48_RS03335 82c84b3c8b9dca0db29c3102ba313660 331 Pfam PF17479 Protein of unknown function (DUF3048) C-terminal domain 210 314 7.2E-22 T 29-03-2018 IPR035328 Protein of unknown function DUF3048, C-terminal domain CXR48_RS17140 3305b525aeee4918248bed1d41634430 248 Gene3D G3DSA:3.30.1890.10 37 159 1.7E-9 T 29-03-2018 CXR48_RS17140 3305b525aeee4918248bed1d41634430 248 Pfam PF02706 Chain length determinant protein 6 94 6.6E-20 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CXR48_RS00285 4568ade5899358559f0c9c949a5a1a7d 86 PIRSF PIRSF037257 1 85 5.8E-37 T 29-03-2018 IPR009366 Protein Veg GO:0042710 CXR48_RS00285 4568ade5899358559f0c9c949a5a1a7d 86 Pfam PF06257 Biofilm formation stimulator VEG 4 74 3.6E-31 T 29-03-2018 IPR009366 Protein Veg GO:0042710 CXR48_RS00285 4568ade5899358559f0c9c949a5a1a7d 86 Gene3D G3DSA:2.30.30.100 2 76 9.7E-33 T 29-03-2018 CXR48_RS10545 8649d75afefa2bfad164222072ae1fb3 122 Gene3D G3DSA:1.20.120.440 5 120 7.8E-39 T 29-03-2018 IPR023351 YppE-like domain CXR48_RS10545 8649d75afefa2bfad164222072ae1fb3 122 SUPERFAMILY SSF140415 2 121 4.97E-42 T 29-03-2018 IPR023351 YppE-like domain CXR48_RS10545 8649d75afefa2bfad164222072ae1fb3 122 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 10 117 1.3E-32 T 29-03-2018 IPR014913 Protein of unknown function DUF1798 CXR48_RS06975 59dff57444120e2bde28feedc9a7ff8a 79 Pfam PF08796 Protein of unknown function (DUF1797) 7 78 1.9E-25 T 29-03-2018 IPR014904 Protein of unknown function DUF1797 CXR48_RS06975 59dff57444120e2bde28feedc9a7ff8a 79 PIRSF PIRSF037356 1 79 5.6E-35 T 29-03-2018 IPR014904 Protein of unknown function DUF1797 CXR48_RS06975 59dff57444120e2bde28feedc9a7ff8a 79 SUPERFAMILY SSF143567 2 79 1.44E-28 T 29-03-2018 CXR48_RS14090 51cb0fd028dc16a1bb0aaa15f276d186 322 SMART SM00729 32 259 6.3E-45 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CXR48_RS14090 51cb0fd028dc16a1bb0aaa15f276d186 322 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 15 314 1.3E-142 T 29-03-2018 IPR005911 Protein YhcC-like GO:0051536 CXR48_RS14090 51cb0fd028dc16a1bb0aaa15f276d186 322 Gene3D G3DSA:3.20.20.70 4 274 2.9E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS14090 51cb0fd028dc16a1bb0aaa15f276d186 322 SUPERFAMILY SSF102114 6 309 7.72E-54 T 29-03-2018 CXR48_RS14090 51cb0fd028dc16a1bb0aaa15f276d186 322 Pfam PF04055 Radical SAM superfamily 52 214 2.9E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CXR48_RS14090 51cb0fd028dc16a1bb0aaa15f276d186 322 Pfam PF16199 Radical_SAM C-terminal domain 220 303 3.9E-26 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CXR48_RS10690 37a0781c141b98e17ad80da7d52158b0 224 PIRSF PIRSF000032 2 224 2.6E-103 T 29-03-2018 IPR023530 Cytochrome b6, PetB GO:0005506|GO:0016021|GO:0020037|GO:0022900|GO:0045158 CXR48_RS10690 37a0781c141b98e17ad80da7d52158b0 224 Gene3D G3DSA:1.20.810.10 2 224 1.3E-75 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CXR48_RS10690 37a0781c141b98e17ad80da7d52158b0 224 SUPERFAMILY SSF81342 6 224 1.91E-60 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CXR48_RS10690 37a0781c141b98e17ad80da7d52158b0 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 2.1E-48 T 29-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CXR48_RS01770 12eb5fa086c99e840ce79fa8041be5d1 185 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 8 185 1.2E-72 T 29-03-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 CXR48_RS01770 12eb5fa086c99e840ce79fa8041be5d1 185 Gene3D G3DSA:3.40.50.10490 1 185 1.3E-41 T 29-03-2018 CXR48_RS01770 12eb5fa086c99e840ce79fa8041be5d1 185 Pfam PF01380 SIS domain 33 154 1.2E-19 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CXR48_RS01770 12eb5fa086c99e840ce79fa8041be5d1 185 SUPERFAMILY SSF53697 4 184 1.84E-41 T 29-03-2018 CXR48_RS12515 0b7b4da8ed47fb4a21ca608b459000c2 122 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 4 111 1.6E-35 T 29-03-2018 IPR018745 Domain of unknown function DUF2294 CXR48_RS18955 1189ea213d23c3387cc08bfa6acf0485 211 Pfam PF07853 Protein of unknown function (DUF1648) 10 57 9.0E-12 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 CXR48_RS18955 1189ea213d23c3387cc08bfa6acf0485 211 PIRSF PIRSF038959 1 211 1.9E-51 T 29-03-2018 IPR026272 Immunity protein SdpI CXR48_RS18955 1189ea213d23c3387cc08bfa6acf0485 211 Pfam PF13630 SdpI/YhfL protein family 133 201 5.9E-20 T 29-03-2018 IPR025962 SdpI/YhfL protein family CXR48_RS08415 a24e30adc2e644cb8218a63302fdf800 428 Pfam PF00675 Insulinase (Peptidase family M16) 65 176 5.7E-18 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CXR48_RS08415 a24e30adc2e644cb8218a63302fdf800 428 SUPERFAMILY SSF63411 283 423 5.24E-18 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CXR48_RS08415 a24e30adc2e644cb8218a63302fdf800 428 Gene3D G3DSA:3.30.830.10 227 428 6.5E-23 T 29-03-2018 CXR48_RS08415 a24e30adc2e644cb8218a63302fdf800 428 Pfam PF05193 Peptidase M16 inactive domain 183 361 4.0E-17 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CXR48_RS08415 a24e30adc2e644cb8218a63302fdf800 428 Gene3D G3DSA:3.30.830.10 3 226 9.6E-50 T 29-03-2018 CXR48_RS08415 a24e30adc2e644cb8218a63302fdf800 428 SUPERFAMILY SSF63411 15 221 1.31E-41 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CXR48_RS03860 261ccf04b02228af4dfe26a4926c380e 253 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 17 249 40.161 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CXR48_RS03860 261ccf04b02228af4dfe26a4926c380e 253 Pfam PF01487 Type I 3-dehydroquinase 20 246 2.2E-69 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CXR48_RS03860 261ccf04b02228af4dfe26a4926c380e 253 SUPERFAMILY SSF51569 1 250 1.39E-78 T 29-03-2018 CXR48_RS03860 261ccf04b02228af4dfe26a4926c380e 253 ProSitePatterns PS01028 Dehydroquinase class I active site. 114 144 - T 29-03-2018 IPR018508 3-dehydroquinate dehydratase, active site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CXR48_RS03860 261ccf04b02228af4dfe26a4926c380e 253 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 17 245 1.3E-72 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CXR48_RS03860 261ccf04b02228af4dfe26a4926c380e 253 Gene3D G3DSA:3.20.20.70 1 252 2.4E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS02215 a20f066e83b6d0e957eab5c11b6c86f8 701 Pfam PF03170 Bacterial cellulose synthase subunit 48 402 4.5E-22 T 29-03-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 CXR48_RS02215 a20f066e83b6d0e957eab5c11b6c86f8 701 Gene3D G3DSA:2.60.120.260 17 153 0.048 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS02215 a20f066e83b6d0e957eab5c11b6c86f8 701 Gene3D G3DSA:2.60.120.260 304 464 0.46 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS02405 2892aade6c8285ec2ec11a96f6901e0c 199 Pfam PF01694 Rhomboid family 54 195 1.3E-40 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CXR48_RS02405 2892aade6c8285ec2ec11a96f6901e0c 199 Gene3D G3DSA:1.20.1540.10 12 194 1.2E-41 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CXR48_RS02405 2892aade6c8285ec2ec11a96f6901e0c 199 SUPERFAMILY SSF144091 12 197 1.7E-42 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CXR48_RS01250 dba4e104544fd5e1f168dccbb1fd7bc1 539 PIRSF PIRSF006060 426 533 18.0 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS01250 dba4e104544fd5e1f168dccbb1fd7bc1 539 PIRSF PIRSF006060 1 459 1.0E-76 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS01250 dba4e104544fd5e1f168dccbb1fd7bc1 539 Pfam PF13520 Amino acid permease 9 428 8.4E-49 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS09180 6d21ef3e92b68d81a0771b247e927969 196 Pfam PF09335 SNARE associated Golgi protein 29 155 8.8E-27 T 29-03-2018 IPR032816 SNARE associated Golgi protein CXR48_RS15495 27bb890e806ebd4f19240dd45253a555 243 PIRSF PIRSF031509 1 243 1.7E-61 T 29-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 CXR48_RS15495 27bb890e806ebd4f19240dd45253a555 243 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 128 240 5.5E-34 T 29-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CXR48_RS02785 731c890862149adafae25132bdc753f6 122 Gene3D G3DSA:1.20.1260.10 4 76 1.2E-7 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS02785 731c890862149adafae25132bdc753f6 122 Pfam PF07875 Coat F domain 19 79 1.7E-16 T 29-03-2018 IPR012851 Spore coat protein CotF-like CXR48_RS03140 60d2482e06f7690f3f27a8868a48bab2 228 Gene3D G3DSA:1.20.5.50 7 143 7.4E-5 T 29-03-2018 CXR48_RS03140 60d2482e06f7690f3f27a8868a48bab2 228 Gene3D G3DSA:1.20.5.50 144 223 0.051 T 29-03-2018 CXR48_RS03140 60d2482e06f7690f3f27a8868a48bab2 228 Pfam PF04012 PspA/IM30 family 3 220 1.7E-38 T 29-03-2018 IPR007157 PspA/IM30 CXR48_RS16700 9cfb8d34ca378df300b1515bdcb6b6b8 94 Pfam PF10719 Late competence development protein ComFB 4 84 9.4E-12 T 29-03-2018 IPR019657 Late competence development protein ComFB CXR48_RS15180 4da5ceb8b79958f8744687b9cc7121ef 289 SUPERFAMILY SSF54060 71 283 7.89E-61 T 29-03-2018 CXR48_RS15180 4da5ceb8b79958f8744687b9cc7121ef 289 Pfam PF04231 Endonuclease I 75 283 4.4E-44 T 29-03-2018 IPR007346 Endonuclease I GO:0004518 CXR48_RS01890 1e1a8ffa869584ed29638a84be149b18 441 Pfam PF00296 Luciferase-like monooxygenase 19 382 4.8E-79 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS01890 1e1a8ffa869584ed29638a84be149b18 441 PIRSF PIRSF000337 3 441 4.0E-168 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CXR48_RS01890 1e1a8ffa869584ed29638a84be149b18 441 SUPERFAMILY SSF51679 5 435 4.84E-143 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS01890 1e1a8ffa869584ed29638a84be149b18 441 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 429 1.5E-187 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CXR48_RS01890 1e1a8ffa869584ed29638a84be149b18 441 Gene3D G3DSA:3.20.20.30 1 441 2.9E-113 T 29-03-2018 CXR48_RS19255 e5dae8a7670d1325aeb922b2c8736977 303 Pfam PF00892 EamA-like transporter family 151 284 6.6E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS19255 e5dae8a7670d1325aeb922b2c8736977 303 Pfam PF00892 EamA-like transporter family 18 139 1.6E-26 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS19255 e5dae8a7670d1325aeb922b2c8736977 303 SUPERFAMILY SSF103481 211 283 4.84E-10 T 29-03-2018 CXR48_RS19255 e5dae8a7670d1325aeb922b2c8736977 303 SUPERFAMILY SSF103481 41 141 2.62E-17 T 29-03-2018 CXR48_RS13965 7ff2a25f0ca80afcab00a85a3b920ef9 425 Pfam PF01547 Bacterial extracellular solute-binding protein 44 333 2.8E-37 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CXR48_RS13965 7ff2a25f0ca80afcab00a85a3b920ef9 425 Gene3D G3DSA:3.40.190.10 18 182 2.3E-31 T 29-03-2018 CXR48_RS13965 7ff2a25f0ca80afcab00a85a3b920ef9 425 Gene3D G3DSA:3.40.190.10 183 367 3.2E-8 T 29-03-2018 CXR48_RS13965 7ff2a25f0ca80afcab00a85a3b920ef9 425 SUPERFAMILY SSF53850 18 413 1.38E-64 T 29-03-2018 CXR48_RS18925 b02d7626af7f6178d4e5758cbeeedf85 326 Gene3D G3DSA:3.20.20.100 1 324 1.7E-105 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS18925 b02d7626af7f6178d4e5758cbeeedf85 326 SUPERFAMILY SSF51430 1 305 1.06E-99 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS18925 b02d7626af7f6178d4e5758cbeeedf85 326 PRINTS PR00069 Aldo-keto reductase signature 106 124 2.2E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS18925 b02d7626af7f6178d4e5758cbeeedf85 326 PRINTS PR00069 Aldo-keto reductase signature 137 154 2.2E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS18925 b02d7626af7f6178d4e5758cbeeedf85 326 Pfam PF00248 Aldo/keto reductase family 14 304 2.9E-75 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS18330 45fb262fefedb92be05b0f856253b1e5 439 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 9 425 9.8E-184 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CXR48_RS18330 45fb262fefedb92be05b0f856253b1e5 439 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 9 425 9.8E-184 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS18330 45fb262fefedb92be05b0f856253b1e5 439 Pfam PF02378 Phosphotransferase system, EIIC 26 350 1.5E-72 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS18330 45fb262fefedb92be05b0f856253b1e5 439 PIRSF PIRSF006351 1 433 6.5E-144 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS03570 0c0d733467f376fc834a02fa2dcf93ec 642 Pfam PF00884 Sulfatase 244 535 9.9E-35 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CXR48_RS03570 0c0d733467f376fc834a02fa2dcf93ec 642 Gene3D G3DSA:3.40.720.10 236 546 1.3E-37 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CXR48_RS03570 0c0d733467f376fc834a02fa2dcf93ec 642 SUPERFAMILY SSF53649 242 636 3.6E-78 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CXR48_RS03570 0c0d733467f376fc834a02fa2dcf93ec 642 PIRSF PIRSF005091 1 619 3.8E-195 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like CXR48_RS01895 62b39cfb2d3518902902fec41abffa9a 163 Gene3D G3DSA:3.40.630.30 4 163 6.7E-20 T 29-03-2018 CXR48_RS01895 62b39cfb2d3518902902fec41abffa9a 163 SUPERFAMILY SSF55729 2 148 1.73E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS01895 62b39cfb2d3518902902fec41abffa9a 163 Pfam PF00583 Acetyltransferase (GNAT) family 47 140 2.0E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS15745 99542bca407ce88f02f895d2ed545c0a 101 Pfam PF02583 Metal-sensitive transcriptional repressor 17 97 5.5E-32 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CXR48_RS13135 da0da90f02404fed423920e423dc3d34 148 SUPERFAMILY SSF111126 16 127 1.2E-22 T 29-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain CXR48_RS13135 da0da90f02404fed423920e423dc3d34 148 Gene3D G3DSA:3.30.1380.20 1 134 5.3E-22 T 29-03-2018 CXR48_RS13135 da0da90f02404fed423920e423dc3d34 148 Pfam PF10702 Protein of unknown function (DUF2507) 20 141 2.1E-47 T 29-03-2018 IPR019642 Protein of unknown function DUF2507 CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Pfam PF08239 Bacterial SH3 domain 112 160 3.8E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Pfam PF08239 Bacterial SH3 domain 186 236 1.9E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Pfam PF08239 Bacterial SH3 domain 267 316 6.7E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Pfam PF08239 Bacterial SH3 domain 39 88 6.3E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Gene3D G3DSA:3.40.630.40 322 520 3.2E-54 T 29-03-2018 CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 SUPERFAMILY SSF53187 344 518 9.1E-52 T 29-03-2018 CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 SMART SM00646 406 515 7.6E-34 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 347 515 4.2E-44 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Gene3D G3DSA:2.40.50.110 95 162 1.2E-19 T 29-03-2018 CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Gene3D G3DSA:2.40.50.110 244 321 3.3E-12 T 29-03-2018 CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Gene3D G3DSA:2.40.50.110 163 239 7.3E-17 T 29-03-2018 CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 PIRSF PIRSF037846 168 519 2.1E-145 T 29-03-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 PIRSF PIRSF037846 1 201 2.2E-64 T 29-03-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 SMART SM00287 29 91 1.1E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 SMART SM00287 100 164 2.5E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 SMART SM00287 178 240 1.4E-16 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 SMART SM00287 259 321 1.2E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CXR48_RS12710 d499b20c4bbaea7caadae5d2f213aa98 520 Gene3D G3DSA:2.30.30.410 21 94 4.3E-14 T 29-03-2018 CXR48_RS02060 9160910d321e285940c9861fd2a89fc3 479 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 14 352 1.8E-187 T 29-03-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CXR48_RS02060 9160910d321e285940c9861fd2a89fc3 479 Pfam PF02378 Phosphotransferase system, EIIC 24 282 7.5E-18 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS02060 9160910d321e285940c9861fd2a89fc3 479 Gene3D G3DSA:3.40.50.2300 379 479 1.9E-22 T 29-03-2018 CXR48_RS02060 9160910d321e285940c9861fd2a89fc3 479 SUPERFAMILY SSF52794 391 478 1.02E-27 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS02060 9160910d321e285940c9861fd2a89fc3 479 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 392 476 9.3E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CXR48_RS17280 e7de40c40adf50651746b1493e869d92 165 Gene3D G3DSA:3.40.630.30 1 165 5.4E-34 T 29-03-2018 CXR48_RS17280 e7de40c40adf50651746b1493e869d92 165 Pfam PF00583 Acetyltransferase (GNAT) family 35 138 1.0E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS17280 e7de40c40adf50651746b1493e869d92 165 SUPERFAMILY SSF55729 3 164 2.45E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS10820 e2567fba532b189d07ba95151db218a2 244 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 17 239 4.0E-94 T 29-03-2018 CXR48_RS08250 5fa519c9ea4355f09d8718a4c0bc1008 265 Pfam PF01148 Cytidylyltransferase family 5 264 5.4E-73 T 29-03-2018 CXR48_RS08250 5fa519c9ea4355f09d8718a4c0bc1008 265 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 222 248 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CXR48_RS06940 825fcfed8901cf46d97258bcb8871bb1 430 SUPERFAMILY SSF103473 5 406 4.45E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS06940 825fcfed8901cf46d97258bcb8871bb1 430 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 9 377 2.8E-120 T 29-03-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 CXR48_RS06940 825fcfed8901cf46d97258bcb8871bb1 430 Gene3D G3DSA:1.20.1250.20 215 420 1.2E-18 T 29-03-2018 CXR48_RS06940 825fcfed8901cf46d97258bcb8871bb1 430 Gene3D G3DSA:1.20.1250.20 1 196 1.5E-20 T 29-03-2018 CXR48_RS06940 825fcfed8901cf46d97258bcb8871bb1 430 Pfam PF07690 Major Facilitator Superfamily 12 356 3.0E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS01570 091c519cc180710f3d9fdfd7b69130e9 362 PIRSF PIRSF026508 1 362 5.1E-130 T 29-03-2018 IPR008863 Toxic anion resistance CXR48_RS01570 091c519cc180710f3d9fdfd7b69130e9 362 Pfam PF05816 Toxic anion resistance protein (TelA) 34 359 8.4E-110 T 29-03-2018 IPR008863 Toxic anion resistance CXR48_RS10755 c4f2bf4793600e5051a62a2dcf08b633 515 Pfam PF00425 chorismate binding enzyme 231 484 6.8E-93 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CXR48_RS10755 c4f2bf4793600e5051a62a2dcf08b633 515 Gene3D G3DSA:3.60.120.10 16 494 2.4E-152 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CXR48_RS10755 c4f2bf4793600e5051a62a2dcf08b633 515 PRINTS PR00095 Anthranilate synthase component I signature 332 345 4.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS10755 c4f2bf4793600e5051a62a2dcf08b633 515 PRINTS PR00095 Anthranilate synthase component I signature 441 455 4.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS10755 c4f2bf4793600e5051a62a2dcf08b633 515 PRINTS PR00095 Anthranilate synthase component I signature 426 440 4.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS10755 c4f2bf4793600e5051a62a2dcf08b633 515 PRINTS PR00095 Anthranilate synthase component I signature 346 359 4.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS10755 c4f2bf4793600e5051a62a2dcf08b633 515 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 29 492 7.5E-183 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS10755 c4f2bf4793600e5051a62a2dcf08b633 515 SUPERFAMILY SSF56322 18 497 2.35E-146 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CXR48_RS10755 c4f2bf4793600e5051a62a2dcf08b633 515 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 167 4.7E-28 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CXR48_RS00595 9372a641e22f9e543886a53195fd22ee 366 SMART SM00670 166 273 1.5E-14 T 29-03-2018 IPR002716 PIN domain CXR48_RS00595 9372a641e22f9e543886a53195fd22ee 366 SUPERFAMILY SSF88723 167 294 3.06E-23 T 29-03-2018 IPR029060 PIN domain-like CXR48_RS00595 9372a641e22f9e543886a53195fd22ee 366 Gene3D G3DSA:3.40.50.1010 161 297 6.0E-26 T 29-03-2018 IPR029060 PIN domain-like CXR48_RS18285 42b80081ef66e60b36465c3fb975ed58 196 SUPERFAMILY SSF50486 6 196 1.73E-62 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CXR48_RS18285 42b80081ef66e60b36465c3fb975ed58 196 Gene3D G3DSA:3.10.300.10 4 196 9.4E-66 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CXR48_RS18285 42b80081ef66e60b36465c3fb975ed58 196 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 10 195 33.295 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CXR48_RS18285 42b80081ef66e60b36465c3fb975ed58 196 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 8 195 6.0E-76 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CXR48_RS18285 42b80081ef66e60b36465c3fb975ed58 196 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 11 192 6.3E-58 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CXR48_RS17650 a917876885ac5cd67e253cbf6cbe4ec7 396 Gene3D G3DSA:1.20.1250.20 5 193 5.0E-23 T 29-03-2018 CXR48_RS17650 a917876885ac5cd67e253cbf6cbe4ec7 396 Pfam PF07690 Major Facilitator Superfamily 16 341 3.7E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS17650 a917876885ac5cd67e253cbf6cbe4ec7 396 SUPERFAMILY SSF103473 7 387 1.44E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS17650 a917876885ac5cd67e253cbf6cbe4ec7 396 Gene3D G3DSA:1.20.1250.20 194 392 7.4E-31 T 29-03-2018 CXR48_RS01215 42133e62ef0e803513ce7d30569c8b1c 507 Gene3D G3DSA:3.50.50.60 1 498 1.5E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01215 42133e62ef0e803513ce7d30569c8b1c 507 Pfam PF01593 Flavin containing amine oxidoreductase 17 490 9.8E-13 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CXR48_RS01215 42133e62ef0e803513ce7d30569c8b1c 507 SUPERFAMILY SSF51905 457 495 1.94E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01215 42133e62ef0e803513ce7d30569c8b1c 507 SUPERFAMILY SSF51905 6 326 1.94E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01040 b0a98e7fd83226c0e79968e4c945b6a1 455 Pfam PF00367 phosphotransferase system, EIIB 12 44 1.9E-11 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS01040 b0a98e7fd83226c0e79968e4c945b6a1 455 Gene3D G3DSA:3.30.1360.60 8 84 7.3E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS01040 b0a98e7fd83226c0e79968e4c945b6a1 455 SUPERFAMILY SSF55604 10 84 3.53E-16 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS01040 b0a98e7fd83226c0e79968e4c945b6a1 455 Pfam PF02378 Phosphotransferase system, EIIC 119 389 1.1E-37 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS15395 d85d84519f86511124fccbc83a1855c2 248 Gene3D G3DSA:2.40.400.10 15 246 3.5E-59 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CXR48_RS15395 d85d84519f86511124fccbc83a1855c2 248 Pfam PF06314 Acetoacetate decarboxylase (ADC) 15 245 5.2E-72 T 29-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CXR48_RS15395 d85d84519f86511124fccbc83a1855c2 248 SUPERFAMILY SSF160104 8 245 8.63E-81 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 Gene3D G3DSA:1.20.120.570 407 561 4.2E-14 T 29-03-2018 CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 Gene3D G3DSA:3.40.1710.10 44 209 4.1E-25 T 29-03-2018 CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 468 494 2.3E-4 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 562 764 3.3E-73 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 SUPERFAMILY SSF57997 201 364 9.15E-6 T 29-03-2018 CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 Gene3D G3DSA:1.20.120.330 279 382 9.7E-5 T 29-03-2018 CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 7 170 2.6E-60 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 Gene3D G3DSA:1.10.287.950 210 278 5.8E-6 T 29-03-2018 CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 Pfam PF12698 ABC-2 family transporter protein 21 154 1.2E-10 T 29-03-2018 CXR48_RS05070 d45d0e0a85efc9f0c3a5a36b4ed02721 777 Pfam PF12698 ABC-2 family transporter protein 492 758 7.0E-15 T 29-03-2018 CXR48_RS09025 4ad2c1606cd76e886b418aaf0ecebf56 358 Gene3D G3DSA:3.20.20.150 1 358 4.5E-97 T 29-03-2018 CXR48_RS09025 4ad2c1606cd76e886b418aaf0ecebf56 358 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 350 3.3E-157 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CXR48_RS09025 4ad2c1606cd76e886b418aaf0ecebf56 358 PIRSF PIRSF016049 1 169 5.0E-50 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CXR48_RS09025 4ad2c1606cd76e886b418aaf0ecebf56 358 PIRSF PIRSF016049 152 356 1.4E-74 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CXR48_RS09025 4ad2c1606cd76e886b418aaf0ecebf56 358 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 358 157.295 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CXR48_RS09025 4ad2c1606cd76e886b418aaf0ecebf56 358 SUPERFAMILY SSF51658 1 347 4.83E-83 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS09025 4ad2c1606cd76e886b418aaf0ecebf56 358 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 351 2.9E-159 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CXR48_RS19390 9c268fee09e1d37c84e64f064643fcd8 283 SMART SM00470 25 114 1.4E-38 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CXR48_RS19390 9c268fee09e1d37c84e64f064643fcd8 283 Pfam PF02195 ParB-like nuclease domain 25 113 4.8E-27 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CXR48_RS19390 9c268fee09e1d37c84e64f064643fcd8 283 SUPERFAMILY SSF110849 25 116 6.02E-29 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CXR48_RS19390 9c268fee09e1d37c84e64f064643fcd8 283 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 21 197 3.2E-68 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CXR48_RS19390 9c268fee09e1d37c84e64f064643fcd8 283 SUPERFAMILY SSF109709 107 217 7.32E-35 T 29-03-2018 CXR48_RS19390 9c268fee09e1d37c84e64f064643fcd8 283 Gene3D G3DSA:1.10.10.730 115 162 3.4E-18 T 29-03-2018 CXR48_RS19390 9c268fee09e1d37c84e64f064643fcd8 283 Gene3D G3DSA:3.90.1530.10 12 114 1.1E-37 T 29-03-2018 CXR48_RS18310 1875957fac716e84da2a090e34696617 116 Pfam PF01022 Bacterial regulatory protein, arsR family 22 67 1.1E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18310 1875957fac716e84da2a090e34696617 116 SUPERFAMILY SSF46785 13 91 9.87E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18310 1875957fac716e84da2a090e34696617 116 SMART SM00418 15 98 7.1E-32 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18310 1875957fac716e84da2a090e34696617 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 8.5E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18310 1875957fac716e84da2a090e34696617 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 17 32 8.5E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18310 1875957fac716e84da2a090e34696617 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 47 8.5E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18310 1875957fac716e84da2a090e34696617 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 8.5E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS18310 1875957fac716e84da2a090e34696617 116 Gene3D G3DSA:1.10.10.10 1 114 3.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS16245 b4ddf9da35f3494639c5bead61dd2d76 52 Pfam PF11578 Protein of unknown function (DUF3237) 6 51 6.8E-9 T 29-03-2018 IPR020915 Uncharacterised protein family UPF0311 CXR48_RS16245 b4ddf9da35f3494639c5bead61dd2d76 52 Gene3D G3DSA:2.40.160.20 2 52 6.8E-12 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CXR48_RS14155 10a431563fd8d7103640041891ea65e9 334 Gene3D G3DSA:3.40.190.10 28 135 2.3E-12 T 29-03-2018 CXR48_RS14155 10a431563fd8d7103640041891ea65e9 334 SUPERFAMILY SSF53850 33 257 7.25E-35 T 29-03-2018 CXR48_RS14155 10a431563fd8d7103640041891ea65e9 334 Pfam PF13379 NMT1-like family 42 263 2.6E-26 T 29-03-2018 CXR48_RS14155 10a431563fd8d7103640041891ea65e9 334 Gene3D G3DSA:3.40.190.10 136 331 2.0E-31 T 29-03-2018 CXR48_RS08375 88bccff4baa3a94d3e962dc6b8dba6fe 245 SUPERFAMILY SSF52096 29 228 3.02E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS08375 88bccff4baa3a94d3e962dc6b8dba6fe 245 Gene3D G3DSA:3.90.226.10 25 238 4.4E-28 T 29-03-2018 CXR48_RS08375 88bccff4baa3a94d3e962dc6b8dba6fe 245 Pfam PF00574 Clp protease 44 220 3.8E-35 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CXR48_RS06425 2992e60d5b236724d013bb1796a79c1a 274 Gene3D G3DSA:3.40.50.10780 1 210 5.3E-82 T 29-03-2018 IPR027476 D-aminopeptidase, N-terminal CXR48_RS06425 2992e60d5b236724d013bb1796a79c1a 274 PIRSF PIRSF015853 1 271 1.5E-106 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CXR48_RS06425 2992e60d5b236724d013bb1796a79c1a 274 SUPERFAMILY SSF63992 1 274 2.09E-101 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CXR48_RS06425 2992e60d5b236724d013bb1796a79c1a 274 Gene3D G3DSA:3.30.1360.130 211 269 3.6E-23 T 29-03-2018 CXR48_RS06425 2992e60d5b236724d013bb1796a79c1a 274 Pfam PF04951 D-aminopeptidase 1 262 7.4E-93 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CXR48_RS04340 3d29f2c61d01a8b05f86bfafc5fa0727 232 Pfam PF03575 Peptidase family S51 4 197 5.8E-59 T 29-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CXR48_RS04340 3d29f2c61d01a8b05f86bfafc5fa0727 232 SUPERFAMILY SSF52317 8 199 3.61E-30 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS04340 3d29f2c61d01a8b05f86bfafc5fa0727 232 Gene3D G3DSA:3.40.50.880 2 227 3.3E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS15335 c86518bda60f58d1acb1348e45e1ea96 118 Pfam PF03960 ArsC family 6 115 1.6E-17 T 29-03-2018 IPR006660 Arsenate reductase-like CXR48_RS15335 c86518bda60f58d1acb1348e45e1ea96 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 117 7.1E-34 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CXR48_RS15335 c86518bda60f58d1acb1348e45e1ea96 118 SUPERFAMILY SSF52833 4 117 5.61E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS15335 c86518bda60f58d1acb1348e45e1ea96 118 Gene3D G3DSA:3.40.30.10 1 117 3.4E-34 T 29-03-2018 CXR48_RS12045 908f67799517f64282776dc8a3e287e3 193 Gene3D G3DSA:3.40.50.1000 47 186 7.6E-26 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12045 908f67799517f64282776dc8a3e287e3 193 PIRSF PIRSF021362 1 191 2.2E-85 T 29-03-2018 IPR009206 Nucleotidase, putative CXR48_RS12045 908f67799517f64282776dc8a3e287e3 193 SUPERFAMILY SSF56784 61 162 3.79E-21 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS12045 908f67799517f64282776dc8a3e287e3 193 SUPERFAMILY SSF56784 4 15 3.79E-21 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS14740 cbade10e7c77fce6e02ce81776d081fc 124 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 108 1.6E-33 T 29-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CXR48_RS14740 cbade10e7c77fce6e02ce81776d081fc 124 Pfam PF03334 Na+/H+ antiporter subunit 12 93 7.3E-26 T 29-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CXR48_RS16215 e8d9b4da85599a618b8e2a136baf300a 482 PRINTS PR00878 Cholinesterase signature 105 134 2.4E-6 T 29-03-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 CXR48_RS16215 e8d9b4da85599a618b8e2a136baf300a 482 PRINTS PR00878 Cholinesterase signature 395 407 2.4E-6 T 29-03-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 CXR48_RS16215 e8d9b4da85599a618b8e2a136baf300a 482 Pfam PF00135 Carboxylesterase family 4 469 3.6E-125 T 29-03-2018 IPR002018 Carboxylesterase, type B CXR48_RS16215 e8d9b4da85599a618b8e2a136baf300a 482 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 81 91 - T 29-03-2018 IPR019819 Carboxylesterase type B, conserved site CXR48_RS16215 e8d9b4da85599a618b8e2a136baf300a 482 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 177 192 - T 29-03-2018 IPR019826 Carboxylesterase type B, active site CXR48_RS16215 e8d9b4da85599a618b8e2a136baf300a 482 SUPERFAMILY SSF53474 4 462 2.03E-138 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS16215 e8d9b4da85599a618b8e2a136baf300a 482 Gene3D G3DSA:3.40.50.1820 1 481 4.2E-148 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS10975 21a872432018c14d5a212984f9cc7778 179 Pfam PF00578 AhpC/TSA family 40 155 3.3E-35 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CXR48_RS10975 21a872432018c14d5a212984f9cc7778 179 ProSitePatterns PS00194 Thioredoxin family active site. 67 85 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CXR48_RS10975 21a872432018c14d5a212984f9cc7778 179 SUPERFAMILY SSF52833 39 173 1.27E-43 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS10975 21a872432018c14d5a212984f9cc7778 179 Gene3D G3DSA:3.40.30.10 29 177 2.1E-42 T 29-03-2018 CXR48_RS13435 f9d6fea597bfca804f2055fb908c4234 210 Pfam PF02659 Putative manganese efflux pump 3 81 9.2E-13 T 29-03-2018 IPR003810 Putative manganese efflux pump CXR48_RS13435 f9d6fea597bfca804f2055fb908c4234 210 Pfam PF02659 Putative manganese efflux pump 123 208 3.4E-11 T 29-03-2018 IPR003810 Putative manganese efflux pump CXR48_RS13435 f9d6fea597bfca804f2055fb908c4234 210 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 4 210 6.6E-79 T 29-03-2018 IPR014205 Sporulation protein YtaF CXR48_RS08170 62fa4301f893658cd6e7af9fc060fe9b 359 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 13 358 2.8E-136 T 29-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 CXR48_RS08170 62fa4301f893658cd6e7af9fc060fe9b 359 Pfam PF01312 FlhB HrpN YscU SpaS Family 12 352 4.2E-133 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CXR48_RS08170 62fa4301f893658cd6e7af9fc060fe9b 359 Gene3D G3DSA:3.40.1690.10 223 358 1.6E-56 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CXR48_RS08170 62fa4301f893658cd6e7af9fc060fe9b 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 213 231 2.5E-43 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CXR48_RS08170 62fa4301f893658cd6e7af9fc060fe9b 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 233 250 2.5E-43 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CXR48_RS08170 62fa4301f893658cd6e7af9fc060fe9b 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 307 328 2.5E-43 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CXR48_RS08170 62fa4301f893658cd6e7af9fc060fe9b 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 277 292 2.5E-43 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CXR48_RS08170 62fa4301f893658cd6e7af9fc060fe9b 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 15 37 2.5E-43 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CXR48_RS08170 62fa4301f893658cd6e7af9fc060fe9b 359 SUPERFAMILY SSF160544 249 356 1.22E-42 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CXR48_RS16610 979d23b449cce0fb8e79600f09ed58b1 282 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 222 276 1.0E-20 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CXR48_RS16610 979d23b449cce0fb8e79600f09ed58b1 282 PIRSF PIRSF006483 1 282 5.3E-82 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS16610 979d23b449cce0fb8e79600f09ed58b1 282 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 14 216 5.7E-61 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS03520 7f1e2322d6a452dd35c63e8923845b1f 108 Gene3D G3DSA:3.30.70.100 1 107 3.7E-23 T 29-03-2018 CXR48_RS03520 7f1e2322d6a452dd35c63e8923845b1f 108 SUPERFAMILY SSF54909 1 98 2.11E-23 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CXR48_RS03520 7f1e2322d6a452dd35c63e8923845b1f 108 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 78 7.2E-17 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CXR48_RS05265 d70daa73fd87b4f8fc8483946e118ac2 165 SUPERFAMILY SSF47240 18 140 3.91E-24 T 29-03-2018 IPR009078 Ferritin-like superfamily CXR48_RS05265 d70daa73fd87b4f8fc8483946e118ac2 165 Gene3D G3DSA:1.20.1260.10 7 78 1.1E-10 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS05265 d70daa73fd87b4f8fc8483946e118ac2 165 Gene3D G3DSA:1.20.1260.10 81 144 3.8E-9 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS05265 d70daa73fd87b4f8fc8483946e118ac2 165 Pfam PF02915 Rubrerythrin 22 136 1.9E-10 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CXR48_RS07445 b2b4c3599973962f947c0079ce5f4c8c 119 SUPERFAMILY SSF160755 1 114 4.84E-38 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CXR48_RS07445 b2b4c3599973962f947c0079ce5f4c8c 119 Gene3D G3DSA:3.30.310.100 1 116 2.4E-36 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CXR48_RS07445 b2b4c3599973962f947c0079ce5f4c8c 119 Pfam PF08868 YugN-like family 5 90 1.9E-14 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CXR48_RS19205 970f41a0532a946e2680a8f8b8eb3e29 144 Pfam PF01047 MarR family 32 89 1.1E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19205 970f41a0532a946e2680a8f8b8eb3e29 144 SMART SM00347 25 125 5.5E-28 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19205 970f41a0532a946e2680a8f8b8eb3e29 144 SUPERFAMILY SSF46785 12 140 1.39E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS19205 970f41a0532a946e2680a8f8b8eb3e29 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 4.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19205 970f41a0532a946e2680a8f8b8eb3e29 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 4.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19205 970f41a0532a946e2680a8f8b8eb3e29 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 4.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19205 970f41a0532a946e2680a8f8b8eb3e29 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 4.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS19205 970f41a0532a946e2680a8f8b8eb3e29 144 Gene3D G3DSA:1.10.10.10 3 144 1.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS03890 8d177811a551071502362190364f3d1f 392 SUPERFAMILY SSF103473 4 379 2.75E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS03890 8d177811a551071502362190364f3d1f 392 Gene3D G3DSA:1.20.1250.20 194 388 6.9E-24 T 29-03-2018 CXR48_RS03890 8d177811a551071502362190364f3d1f 392 Gene3D G3DSA:1.20.1250.20 2 193 2.6E-23 T 29-03-2018 CXR48_RS03890 8d177811a551071502362190364f3d1f 392 Pfam PF07690 Major Facilitator Superfamily 10 191 2.7E-18 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS03890 8d177811a551071502362190364f3d1f 392 Pfam PF07690 Major Facilitator Superfamily 211 386 1.6E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS00800 74be2f7d785ba7e3f49c9ced117aa06d 61 SUPERFAMILY SSF57716 3 61 6.99E-22 T 29-03-2018 CXR48_RS00800 74be2f7d785ba7e3f49c9ced117aa06d 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.948 T 29-03-2018 IPR023053 Ribosomal protein S14, type Z CXR48_RS00800 74be2f7d785ba7e3f49c9ced117aa06d 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00800 74be2f7d785ba7e3f49c9ced117aa06d 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.3E-25 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00800 74be2f7d785ba7e3f49c9ced117aa06d 61 Gene3D G3DSA:4.10.830.10 1 61 2.2E-21 T 29-03-2018 CXR48_RS08105 cb67c344b519756af70bd8d4aedf5042 204 Pfam PF03448 MgtE intracellular N domain 139 200 1.4E-7 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CXR48_RS08105 cb67c344b519756af70bd8d4aedf5042 204 Gene3D G3DSA:1.20.5.50 44 126 8.5E-6 T 29-03-2018 CXR48_RS08105 cb67c344b519756af70bd8d4aedf5042 204 SUPERFAMILY SSF158791 135 197 2.35E-7 T 29-03-2018 CXR48_RS08105 cb67c344b519756af70bd8d4aedf5042 204 Gene3D G3DSA:1.10.220.30 140 203 2.3E-8 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CXR48_RS01550 e08989ad7c79d93334ef373651c83991 193 Gene3D G3DSA:2.60.60.30 19 187 2.5E-63 T 29-03-2018 CXR48_RS01550 e08989ad7c79d93334ef373651c83991 193 Pfam PF02342 TerD domain 1 188 3.2E-83 T 29-03-2018 IPR003325 TerD domain GO:0006950 CXR48_RS05925 189b704ef4712797d0136ade84a2478d 157 SMART SM00347 28 129 1.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS05925 189b704ef4712797d0136ade84a2478d 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CXR48_RS05925 189b704ef4712797d0136ade84a2478d 157 Pfam PF01047 MarR family 35 91 3.8E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS05925 189b704ef4712797d0136ade84a2478d 157 SUPERFAMILY SSF46785 6 148 3.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS05925 189b704ef4712797d0136ade84a2478d 157 Gene3D G3DSA:1.10.10.10 1 132 2.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15505 b5f045a88824e3f41f5a05ea17e8fbdc 225 Gene3D G3DSA:1.20.5.50 11 145 4.2E-4 T 29-03-2018 CXR48_RS15505 b5f045a88824e3f41f5a05ea17e8fbdc 225 Pfam PF04012 PspA/IM30 family 1 218 8.3E-58 T 29-03-2018 IPR007157 PspA/IM30 CXR48_RS11825 8bfc33ce84513f6e2d525e0663683bd6 261 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 44 3.1E-10 T 29-03-2018 IPR023833 Signal peptide, camelysin CXR48_RS11825 8bfc33ce84513f6e2d525e0663683bd6 261 Pfam PF12389 Camelysin metallo-endopeptidase 3 235 5.2E-37 T 29-03-2018 IPR022121 Peptidase M73, camelysin CXR48_RS11825 8bfc33ce84513f6e2d525e0663683bd6 261 Gene3D G3DSA:2.60.40.10 28 244 0.0029 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS01645 d9f9a07290c09536ccebae157b1046fa 442 Pfam PF00324 Amino acid permease 18 376 5.1E-43 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS01645 d9f9a07290c09536ccebae157b1046fa 442 PIRSF PIRSF006060 1 439 2.0E-47 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS04410 ae139909d3d39d2423cb3962471c2477 378 Pfam PF00296 Luciferase-like monooxygenase 1 323 2.3E-91 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS04410 ae139909d3d39d2423cb3962471c2477 378 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 347 2.0E-190 T 29-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 CXR48_RS04410 ae139909d3d39d2423cb3962471c2477 378 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 2 375 70.494 T 29-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 CXR48_RS04410 ae139909d3d39d2423cb3962471c2477 378 Gene3D G3DSA:3.20.20.30 1 359 2.0E-93 T 29-03-2018 CXR48_RS04410 ae139909d3d39d2423cb3962471c2477 378 SUPERFAMILY SSF51679 1 347 3.79E-101 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CXR48_RS16810 795b0495bb6e7f28bc8e3132b2b73ea3 514 Pfam PF00005 ABC transporter 41 171 1.2E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS16810 795b0495bb6e7f28bc8e3132b2b73ea3 514 SUPERFAMILY SSF52540 35 235 5.44E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS16810 795b0495bb6e7f28bc8e3132b2b73ea3 514 SMART SM00382 49 237 4.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS16810 795b0495bb6e7f28bc8e3132b2b73ea3 514 Gene3D G3DSA:3.40.50.300 1 287 8.1E-51 T 29-03-2018 CXR48_RS16810 795b0495bb6e7f28bc8e3132b2b73ea3 514 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS01015 4da8c5e09891c34b2bbd17c04bb0055d 318 SUPERFAMILY SSF53807 44 303 1.1E-57 T 29-03-2018 CXR48_RS01015 4da8c5e09891c34b2bbd17c04bb0055d 318 Gene3D G3DSA:3.40.50.1980 39 156 1.2E-16 T 29-03-2018 CXR48_RS01015 4da8c5e09891c34b2bbd17c04bb0055d 318 Pfam PF01497 Periplasmic binding protein 86 289 1.5E-35 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CXR48_RS01015 4da8c5e09891c34b2bbd17c04bb0055d 318 Gene3D G3DSA:3.40.50.1980 157 318 2.0E-32 T 29-03-2018 CXR48_RS10450 bb2006dd40a26365be001773f8ddfff5 126 SUPERFAMILY SSF47413 2 67 1.72E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS10450 bb2006dd40a26365be001773f8ddfff5 126 Pfam PF01381 Helix-turn-helix 7 61 2.7E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS10450 bb2006dd40a26365be001773f8ddfff5 126 SMART SM00530 6 61 5.4E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS10450 bb2006dd40a26365be001773f8ddfff5 126 Gene3D G3DSA:1.10.260.40 1 126 4.7E-24 T 29-03-2018 CXR48_RS19190 b07770fb3e77f11b08bc2682f2183579 405 Gene3D G3DSA:1.20.1250.20 3 200 7.3E-14 T 29-03-2018 CXR48_RS19190 b07770fb3e77f11b08bc2682f2183579 405 Gene3D G3DSA:1.20.1250.20 202 400 2.7E-14 T 29-03-2018 CXR48_RS19190 b07770fb3e77f11b08bc2682f2183579 405 SUPERFAMILY SSF103473 4 399 4.32E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS19190 b07770fb3e77f11b08bc2682f2183579 405 Pfam PF07690 Major Facilitator Superfamily 17 319 1.7E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS08405 44eb7e40bc7f67c723b8249c370f6522 1039 Gene3D G3DSA:1.20.1640.10 794 1030 2.6E-26 T 29-03-2018 CXR48_RS08405 44eb7e40bc7f67c723b8249c370f6522 1039 Gene3D G3DSA:1.20.1640.10 106 337 6.6E-35 T 29-03-2018 CXR48_RS08405 44eb7e40bc7f67c723b8249c370f6522 1039 Pfam PF03176 MMPL family 45 365 4.4E-62 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CXR48_RS08405 44eb7e40bc7f67c723b8249c370f6522 1039 Pfam PF03176 MMPL family 742 1034 2.0E-46 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CXR48_RS08405 44eb7e40bc7f67c723b8249c370f6522 1039 SUPERFAMILY SSF82866 811 1034 2.75E-29 T 29-03-2018 CXR48_RS08405 44eb7e40bc7f67c723b8249c370f6522 1039 SUPERFAMILY SSF58104 496 741 6.98E-8 T 29-03-2018 CXR48_RS08405 44eb7e40bc7f67c723b8249c370f6522 1039 SUPERFAMILY SSF82866 138 340 3.66E-34 T 29-03-2018 CXR48_RS08405 44eb7e40bc7f67c723b8249c370f6522 1039 Gene3D G3DSA:1.20.120.570 437 602 3.1E-7 T 29-03-2018 CXR48_RS08405 44eb7e40bc7f67c723b8249c370f6522 1039 Gene3D G3DSA:1.20.120.570 603 778 6.7E-13 T 29-03-2018 CXR48_RS11380 a0f727bdbfe001c3baa205a4a532b732 326 TIGRFAM TIGR04098 biosyn_clust_1: biosynthesis cluster domain 6 290 8.3E-70 T 29-03-2018 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 8.1E-90 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 SUPERFAMILY SSF64484 5 1181 0.0 T 29-03-2018 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1192 18.737 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 378 474 2.0E-29 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 386 5.5E-9 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 Gene3D G3DSA:2.40.40.20 335 477 8.7E-40 T 29-03-2018 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 2.9E-36 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1181 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 1129 5.5E-67 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 Gene3D G3DSA:2.40.50.100 910 1029 7.4E-42 T 29-03-2018 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 759 2.6E-14 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS00695 b3fca18ed98a860d6250572a242c6435 1199 SMART SM00663 224 503 2.2E-185 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CXR48_RS04880 4359f1a42cbaa0b2de5b1e7320cc53a8 288 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 267 6.1E-53 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS04880 4359f1a42cbaa0b2de5b1e7320cc53a8 288 Gene3D G3DSA:3.30.1240.10 83 194 2.5E-42 T 29-03-2018 CXR48_RS04880 4359f1a42cbaa0b2de5b1e7320cc53a8 288 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 240 2.7E-16 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CXR48_RS04880 4359f1a42cbaa0b2de5b1e7320cc53a8 288 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 267 9.7E-43 T 29-03-2018 IPR000150 Cof family GO:0016787 CXR48_RS04880 4359f1a42cbaa0b2de5b1e7320cc53a8 288 SUPERFAMILY SSF56784 3 272 1.58E-54 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS11480 5638041e695f5c408679e407d55ec98d 317 Pfam PF06081 Aromatic acid exporter family member 1 2 142 6.0E-54 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CXR48_RS11480 5638041e695f5c408679e407d55ec98d 317 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 310 9.9E-60 T 29-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal CXR48_RS12645 a0b570bd3c50c251db1b978ad93a7b4a 43 Pfam PF13056 Protein of unknown function (DUF3918) 1 43 7.0E-19 T 29-03-2018 IPR025029 Protein of unknown function DUF3918 CXR48_RS14000 8264c28a51ea9bfdf797abf81e4ab733 109 Pfam PF14074 Protein of unknown function (DUF4257) 5 84 3.0E-34 T 29-03-2018 IPR025353 Protein of unknown function DUF4257) CXR48_RS14000 8264c28a51ea9bfdf797abf81e4ab733 109 ProDom PD866859 YTVB PLASMID MEMBRANE TRANSMEMBRANE 1 107 1.0E-46 T 29-03-2018 CXR48_RS15915 be5cf3d0a1ab515dd4606e6873665558 224 Gene3D G3DSA:1.10.3720.10 3 215 1.6E-30 T 29-03-2018 CXR48_RS15915 be5cf3d0a1ab515dd4606e6873665558 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 209 3.3E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15915 be5cf3d0a1ab515dd4606e6873665558 224 SUPERFAMILY SSF161098 18 199 2.35E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS02745 a3d90e8c722bdb644e89c1d4a881f90c 206 Gene3D G3DSA:2.30.110.10 1 199 3.9E-54 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CXR48_RS02745 a3d90e8c722bdb644e89c1d4a881f90c 206 PIRSF PIRSF010372 1 201 2.7E-55 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type CXR48_RS02745 a3d90e8c722bdb644e89c1d4a881f90c 206 SUPERFAMILY SSF50475 8 176 1.81E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CXR48_RS02745 a3d90e8c722bdb644e89c1d4a881f90c 206 Pfam PF04299 Putative FMN-binding domain 1 156 1.8E-46 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type CXR48_RS13745 e0abd8ce779ee9c0d7c61b73143e2771 243 Pfam PF03591 AzlC protein 28 168 6.2E-40 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease CXR48_RS06570 87c31172ee572d75fb3db6970d260a35 277 SUPERFAMILY SSF52091 167 275 1.84E-14 T 29-03-2018 IPR002645 STAS domain CXR48_RS06570 87c31172ee572d75fb3db6970d260a35 277 Gene3D G3DSA:3.30.750.24 169 277 2.9E-12 T 29-03-2018 IPR002645 STAS domain CXR48_RS06570 87c31172ee572d75fb3db6970d260a35 277 Pfam PF01740 STAS domain 175 270 5.3E-14 T 29-03-2018 IPR002645 STAS domain CXR48_RS09290 50f376b4006389eb7bc043cf673a01c6 76 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 2 50 2.6E-11 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CXR48_RS09290 50f376b4006389eb7bc043cf673a01c6 76 Pfam PF12728 Helix-turn-helix domain 2 50 3.5E-7 T 29-03-2018 CXR48_RS09535 021ddee93f96336f19b4b4cad4c1cad2 46 Pfam PF13217 Protein of unknown function (DUF4025) 6 43 2.4E-7 T 29-03-2018 IPR025100 Protein of unknown function DUF4025 CXR48_RS05180 ca3d0e2c93fa11438d42631edcea2d67 77 Pfam PF08858 IDEAL domain 34 70 7.5E-15 T 29-03-2018 IPR014957 IDEAL domain CXR48_RS05180 ca3d0e2c93fa11438d42631edcea2d67 77 SMART SM00914 34 70 4.3E-13 T 29-03-2018 IPR014957 IDEAL domain CXR48_RS10560 2c2d9ca04abd720aa957db88056d5f30 320 Pfam PF10720 Protein of unknown function (DUF2515) 15 313 5.9E-123 T 29-03-2018 IPR019658 Protein of unknown function DUF2515 CXR48_RS18115 26809fe0045810eae9a111a282a35b6d 53 Pfam PF08671 Anti-repressor SinI 9 35 7.3E-10 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CXR48_RS18115 26809fe0045810eae9a111a282a35b6d 53 SUPERFAMILY SSF47406 8 35 1.7E-5 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CXR48_RS06225 7c0c186ed1988d8b3c5f448cb3838fe9 172 Gene3D G3DSA:1.10.10.10 7 164 5.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS06225 7c0c186ed1988d8b3c5f448cb3838fe9 172 SUPERFAMILY SSF88659 98 163 1.22E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS06225 7c0c186ed1988d8b3c5f448cb3838fe9 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 65 160 3.0E-12 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS06225 7c0c186ed1988d8b3c5f448cb3838fe9 172 Pfam PF08281 Sigma-70, region 4 105 157 1.9E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS08625 2426d38fce68fe7657a64e2db2f7dc8e 117 Pfam PF00893 Small Multidrug Resistance protein 5 93 6.5E-28 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CXR48_RS08625 2426d38fce68fe7657a64e2db2f7dc8e 117 SUPERFAMILY SSF103481 6 106 6.41E-21 T 29-03-2018 CXR48_RS12930 9b5f4a2de6e23e6014196011a8723128 250 Pfam PF01478 Type IV leader peptidase family 101 204 5.3E-17 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CXR48_RS12930 9b5f4a2de6e23e6014196011a8723128 250 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 8 90 5.3E-25 T 29-03-2018 IPR010627 Peptidase A24A, N-terminal CXR48_RS09955 ee509f1a2a948d4499b9f0ba812d06fa 599 Pfam PF04740 LXG domain of WXG superfamily 2 200 3.6E-51 T 29-03-2018 IPR006829 LXG domain CXR48_RS09955 ee509f1a2a948d4499b9f0ba812d06fa 599 Pfam PF14411 A nuclease of the HNH/ENDO VII superfamily with conserved LHH 513 594 7.8E-29 T 29-03-2018 IPR026834 LHH CXR48_RS15210 1f4928550a2c0c5d85580f77b22786ed 421 Gene3D G3DSA:3.40.190.10 30 205 2.0E-45 T 29-03-2018 CXR48_RS15210 1f4928550a2c0c5d85580f77b22786ed 421 Gene3D G3DSA:3.40.190.10 206 374 2.5E-10 T 29-03-2018 CXR48_RS15210 1f4928550a2c0c5d85580f77b22786ed 421 Pfam PF01547 Bacterial extracellular solute-binding protein 42 331 7.4E-48 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CXR48_RS15210 1f4928550a2c0c5d85580f77b22786ed 421 SUPERFAMILY SSF53850 18 416 3.31E-87 T 29-03-2018 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 PRINTS PR00162 Rieske 2Fe-2S subunit signature 477 489 3.1E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 PRINTS PR00162 Rieske 2Fe-2S subunit signature 489 501 3.1E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 PRINTS PR00162 Rieske 2Fe-2S subunit signature 456 467 3.1E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 Gene3D G3DSA:3.50.50.60 19 412 3.2E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 Pfam PF00355 Rieske [2Fe-2S] domain 427 503 6.6E-12 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 SUPERFAMILY SSF50022 425 504 4.06E-23 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 SUPERFAMILY SSF51971 322 383 3.41E-34 T 29-03-2018 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 SUPERFAMILY SSF51971 28 261 3.41E-34 T 29-03-2018 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 Pfam PF01266 FAD dependent oxidoreductase 32 376 2.9E-43 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CXR48_RS05170 9e8df02eeab81136ca6b95b887e9708e 507 Gene3D G3DSA:2.102.10.10 413 505 1.8E-18 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CXR48_RS01085 ac469f3e537fa0232dd2d0fea4d06378 187 Gene3D G3DSA:1.10.1740.10 3 90 7.0E-27 T 29-03-2018 CXR48_RS01085 ac469f3e537fa0232dd2d0fea4d06378 187 Pfam PF08281 Sigma-70, region 4 130 180 6.0E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS01085 ac469f3e537fa0232dd2d0fea4d06378 187 Pfam PF04542 Sigma-70 region 2 24 89 4.3E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS01085 ac469f3e537fa0232dd2d0fea4d06378 187 SUPERFAMILY SSF88659 117 185 3.18E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS01085 ac469f3e537fa0232dd2d0fea4d06378 187 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 45 76 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS01085 ac469f3e537fa0232dd2d0fea4d06378 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 184 1.3E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS01085 ac469f3e537fa0232dd2d0fea4d06378 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 187 5.0E-109 T 29-03-2018 IPR014294 RNA polymerase sigma-W, bacillaceae CXR48_RS01085 ac469f3e537fa0232dd2d0fea4d06378 187 Gene3D G3DSA:1.10.10.10 91 187 5.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS01085 ac469f3e537fa0232dd2d0fea4d06378 187 SUPERFAMILY SSF88946 8 98 9.1E-31 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CXR48_RS02300 845e1be47dfbcea37c16e467abaaee6e 113 Gene3D G3DSA:2.60.120.10 2 107 1.5E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS02300 845e1be47dfbcea37c16e467abaaee6e 113 SUPERFAMILY SSF51182 12 102 8.67E-20 T 29-03-2018 IPR011051 RmlC-like cupin domain CXR48_RS02300 845e1be47dfbcea37c16e467abaaee6e 113 Pfam PF07883 Cupin domain 41 88 4.3E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CXR48_RS06285 27b4f8f6db736c73c7f4a2ab348c72a9 147 Pfam PF09393 Phage tail tube protein 2 141 5.0E-54 T 29-03-2018 IPR018989 Phage tail tube protein CXR48_RS06285 27b4f8f6db736c73c7f4a2ab348c72a9 147 SUPERFAMILY SSF69279 6 142 1.87E-49 T 29-03-2018 CXR48_RS14055 6d1dc3c531c38c5d6038202fb3696990 328 Pfam PF12730 ABC-2 family transporter protein 7 179 1.4E-6 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CXR48_RS14055 6d1dc3c531c38c5d6038202fb3696990 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 261 280 2.5E-42 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14055 6d1dc3c531c38c5d6038202fb3696990 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 241 255 2.5E-42 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14055 6d1dc3c531c38c5d6038202fb3696990 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 169 181 2.5E-42 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14055 6d1dc3c531c38c5d6038202fb3696990 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 92 106 2.5E-42 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14055 6d1dc3c531c38c5d6038202fb3696990 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 152 166 2.5E-42 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS03385 a236daec34571b168db052daf80468fd 492 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 4 488 3.5E-228 T 29-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 CXR48_RS03385 a236daec34571b168db052daf80468fd 492 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 413 433 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CXR48_RS03385 a236daec34571b168db052daf80468fd 492 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 155 180 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CXR48_RS03385 a236daec34571b168db052daf80468fd 492 Pfam PF00474 Sodium:solute symporter family 33 431 2.3E-106 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS03385 a236daec34571b168db052daf80468fd 492 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 431 5.2E-94 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS09865 c9a5c608492180dcf1b8d48838f3559a 91 Gene3D G3DSA:2.40.50.140 8 89 2.0E-18 T 29-03-2018 CXR48_RS09865 c9a5c608492180dcf1b8d48838f3559a 91 Pfam PF11518 Protein of unknown function (DUF3221) 4 89 1.8E-19 T 29-03-2018 IPR021598 Protein of unknown function DUF3221 CXR48_RS14070 9a4276f7f90baa17a32bf640f61f12f8 130 SMART SM00345 16 75 9.3E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS14070 9a4276f7f90baa17a32bf640f61f12f8 130 Gene3D G3DSA:1.10.10.10 1 77 5.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS14070 9a4276f7f90baa17a32bf640f61f12f8 130 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 3.3E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CXR48_RS14070 9a4276f7f90baa17a32bf640f61f12f8 130 SUPERFAMILY SSF46785 5 79 8.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS00745 960373c2f2d8bc8bbb3f812bca6bff50 95 SUPERFAMILY SSF54189 2 91 1.44E-30 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00745 960373c2f2d8bc8bbb3f812bca6bff50 95 Pfam PF00276 Ribosomal protein L23 6 88 3.4E-32 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CXR48_RS00745 960373c2f2d8bc8bbb3f812bca6bff50 95 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 29-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CXR48_RS00745 960373c2f2d8bc8bbb3f812bca6bff50 95 Gene3D G3DSA:3.30.70.330 2 95 5.9E-31 T 29-03-2018 CXR48_RS00745 960373c2f2d8bc8bbb3f812bca6bff50 95 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 21.84 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CXR48_RS18990 3e569b314f6cd053ab2597c71d13b094 335 Pfam PF00899 ThiF family 107 309 1.1E-33 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CXR48_RS18990 3e569b314f6cd053ab2597c71d13b094 335 SUPERFAMILY SSF69572 108 329 5.76E-43 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CXR48_RS18990 3e569b314f6cd053ab2597c71d13b094 335 Gene3D G3DSA:3.40.50.720 96 334 7.4E-38 T 29-03-2018 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 Gene3D G3DSA:3.40.50.720 1 197 3.3E-56 T 29-03-2018 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 SUPERFAMILY SSF51735 2 194 1.06E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 PIRSF PIRSF500134 2 435 2.4E-179 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 Gene3D G3DSA:3.40.50.720 223 429 1.8E-75 T 29-03-2018 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 291 3.7E-39 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 PIRSF PIRSF000124 2 432 4.9E-142 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 SMART SM00984 314 417 6.1E-45 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 SUPERFAMILY SSF52413 300 427 9.81E-37 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 Gene3D G3DSA:1.20.5.100 200 222 8.2E-15 T 29-03-2018 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 SUPERFAMILY SSF48179 199 296 4.08E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 185 8.5E-68 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 413 1.2E-140 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CXR48_RS16760 ca957c1ddf2f4338da2e93b6c9d4b334 446 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 415 1.9E-31 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CXR48_RS00685 9a860034b3381785a2ee9b6efc3d3662 201 Gene3D G3DSA:3.40.50.150 10 201 1.5E-29 T 29-03-2018 CXR48_RS00685 9a860034b3381785a2ee9b6efc3d3662 201 Pfam PF05175 Methyltransferase small domain 28 197 1.2E-48 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CXR48_RS00685 9a860034b3381785a2ee9b6efc3d3662 201 SUPERFAMILY SSF53335 7 200 8.14E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS04565 b0248d7b3253bed5b395f86baba1129c 179 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 19 174 1.5E-29 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CXR48_RS04565 b0248d7b3253bed5b395f86baba1129c 179 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 9 175 1.2E-51 T 29-03-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ CXR48_RS08235 da37bc620a70403f0771d082e8f78c56 240 Pfam PF00696 Amino acid kinase family 7 217 6.3E-29 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS08235 da37bc620a70403f0771d082e8f78c56 240 PIRSF PIRSF005650 1 240 1.1E-97 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CXR48_RS08235 da37bc620a70403f0771d082e8f78c56 240 Gene3D G3DSA:3.40.1160.10 1 239 6.3E-44 T 29-03-2018 CXR48_RS08235 da37bc620a70403f0771d082e8f78c56 240 SUPERFAMILY SSF53633 4 238 4.32E-74 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CXR48_RS08235 da37bc620a70403f0771d082e8f78c56 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 3.9E-103 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CXR48_RS08235 da37bc620a70403f0771d082e8f78c56 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.203 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CXR48_RS17020 0131c9df1f4e16a9b3cd0916bf92479a 206 SMART SM00903 20 178 2.2E-25 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CXR48_RS17020 0131c9df1f4e16a9b3cd0916bf92479a 206 SUPERFAMILY SSF50475 3 201 3.19E-38 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CXR48_RS17020 0131c9df1f4e16a9b3cd0916bf92479a 206 Pfam PF01613 Flavin reductase like domain 23 170 5.7E-16 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CXR48_RS17020 0131c9df1f4e16a9b3cd0916bf92479a 206 Gene3D G3DSA:2.30.110.10 4 203 8.5E-41 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CXR48_RS15580 9f62dcbeffc49401942c8da79be65d3b 140 Pfam PF14184 Regulatory protein YrvL 11 132 4.3E-25 T 29-03-2018 IPR025912 Regulatory protein YrvL CXR48_RS15580 9f62dcbeffc49401942c8da79be65d3b 140 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 11 129 3.0E-35 T 29-03-2018 CXR48_RS01880 55c41058c4652538ea5d0e0e147e06d3 408 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 229 395 4.8E-33 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CXR48_RS01880 55c41058c4652538ea5d0e0e147e06d3 408 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 397 9.6E-94 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CXR48_RS15670 1a68965c2cd52409dc847690f7bc4e15 381 Pfam PF12698 ABC-2 family transporter protein 19 369 1.1E-37 T 29-03-2018 CXR48_RS15670 1a68965c2cd52409dc847690f7bc4e15 381 Gene3D G3DSA:3.40.1710.10 38 198 2.0E-15 T 29-03-2018 CXR48_RS06630 68b231726c0e99c4397e503d1cceeef5 184 ProDom PD102989 YKOP PLASMID 1 179 6.0E-67 T 29-03-2018 CXR48_RS15705 1fbc2cff39c6efc98060be7ce97a9857 771 Gene3D G3DSA:3.40.50.300 211 601 1.4E-33 T 29-03-2018 CXR48_RS15705 1fbc2cff39c6efc98060be7ce97a9857 771 Pfam PF13538 UvrD-like helicase C-terminal domain 704 752 3.7E-12 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain CXR48_RS15705 1fbc2cff39c6efc98060be7ce97a9857 771 Gene3D G3DSA:3.40.50.300 603 770 1.4E-33 T 29-03-2018 CXR48_RS15705 1fbc2cff39c6efc98060be7ce97a9857 771 SUPERFAMILY SSF52540 205 316 3.34E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS15705 1fbc2cff39c6efc98060be7ce97a9857 771 SUPERFAMILY SSF52540 516 766 3.34E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS15705 1fbc2cff39c6efc98060be7ce97a9857 771 Pfam PF13245 AAA domain 217 580 6.8E-9 T 29-03-2018 CXR48_RS01405 ed01cfeb0317b5137bc57918cd9970c4 112 Pfam PF00085 Thioredoxin 14 87 1.5E-8 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CXR48_RS01405 ed01cfeb0317b5137bc57918cd9970c4 112 SUPERFAMILY SSF52833 9 105 2.71E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS01405 ed01cfeb0317b5137bc57918cd9970c4 112 Gene3D G3DSA:3.40.30.10 2 109 4.9E-15 T 29-03-2018 CXR48_RS10045 c12ed3983f04ddb93fbc638aa00b18e3 202 Pfam PF14005 YpjP-like protein 68 199 1.7E-58 T 29-03-2018 IPR025616 YpjP-like protein CXR48_RS02645 908443466390f240b56fef5e64054a9c 158 SUPERFAMILY SSF109854 8 158 5.49E-32 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CXR48_RS02645 908443466390f240b56fef5e64054a9c 158 Pfam PF12867 DinB superfamily 11 142 5.0E-13 T 29-03-2018 IPR024775 DinB-like domain CXR48_RS02645 908443466390f240b56fef5e64054a9c 158 Gene3D G3DSA:1.20.120.450 1 151 2.6E-17 T 29-03-2018 CXR48_RS16765 8884593ef17083df04d9f933d6a3deae 398 Pfam PF00534 Glycosyl transferases group 1 207 346 7.6E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CXR48_RS16765 8884593ef17083df04d9f933d6a3deae 398 SUPERFAMILY SSF53756 1 388 2.69E-69 T 29-03-2018 CXR48_RS16765 8884593ef17083df04d9f933d6a3deae 398 Pfam PF13439 Glycosyltransferase Family 4 23 197 4.7E-18 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CXR48_RS16765 8884593ef17083df04d9f933d6a3deae 398 Gene3D G3DSA:3.40.50.2000 24 207 1.4E-16 T 29-03-2018 CXR48_RS16765 8884593ef17083df04d9f933d6a3deae 398 Gene3D G3DSA:3.40.50.2000 208 386 1.4E-36 T 29-03-2018 CXR48_RS07045 18819bf047bc6eb2bbf6a36c96be497c 330 Gene3D G3DSA:1.20.5.170 99 210 0.013 T 29-03-2018 CXR48_RS13590 6e7e58486b98d97aab3319218e870ae2 328 SUPERFAMILY SSF53335 42 313 1.15E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS13590 6e7e58486b98d97aab3319218e870ae2 328 Gene3D G3DSA:3.40.50.150 87 328 2.9E-43 T 29-03-2018 CXR48_RS13590 6e7e58486b98d97aab3319218e870ae2 328 Pfam PF02384 N-6 DNA Methylase 97 311 6.6E-15 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CXR48_RS13590 6e7e58486b98d97aab3319218e870ae2 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 121 135 8.2E-8 T 29-03-2018 CXR48_RS13590 6e7e58486b98d97aab3319218e870ae2 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 217 241 8.2E-8 T 29-03-2018 CXR48_RS13590 6e7e58486b98d97aab3319218e870ae2 328 PIRSF PIRSF026567 1 328 5.9E-139 T 29-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted CXR48_RS04950 119681808058b6a953be99f3bddc9e8e 283 SUPERFAMILY SSF54534 118 222 1.31E-33 T 29-03-2018 CXR48_RS04950 119681808058b6a953be99f3bddc9e8e 283 SUPERFAMILY SSF109998 25 164 2.94E-18 T 29-03-2018 IPR027304 Trigger factor/SurA domain CXR48_RS04950 119681808058b6a953be99f3bddc9e8e 283 Gene3D G3DSA:3.10.50.40 131 233 1.3E-37 T 29-03-2018 CXR48_RS04950 119681808058b6a953be99f3bddc9e8e 283 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 37 115 1.3E-5 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CXR48_RS04950 119681808058b6a953be99f3bddc9e8e 283 Pfam PF13616 PPIC-type PPIASE domain 134 224 2.5E-27 T 29-03-2018 CXR48_RS04950 119681808058b6a953be99f3bddc9e8e 283 Hamap MF_01145 Foldase protein PrsA [prsA]. 2 278 21.626 T 29-03-2018 IPR023059 Foldase protein PrsA GO:0003755 CXR48_RS04950 119681808058b6a953be99f3bddc9e8e 283 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 163 183 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CXR48_RS12355 28bd120a7fe211e9a52f384732f02236 243 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 27 230 1.0E-23 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS12355 28bd120a7fe211e9a52f384732f02236 243 SUPERFAMILY SSF52266 23 236 8.33E-38 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS12355 28bd120a7fe211e9a52f384732f02236 243 Gene3D G3DSA:3.40.50.1110 22 237 6.8E-31 T 29-03-2018 CXR48_RS06395 18c5e61ee8a0c086e2073b2e266d4325 438 PIRSF PIRSF006060 1 437 2.0E-79 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS06395 18c5e61ee8a0c086e2073b2e266d4325 438 Pfam PF13520 Amino acid permease 16 408 9.8E-56 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS18800 3975808dea7015c2255c78b8767adf51 103 Gene3D G3DSA:1.10.10.10 7 90 4.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18800 3975808dea7015c2255c78b8767adf51 103 SUPERFAMILY SSF46785 4 100 4.71E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18800 3975808dea7015c2255c78b8767adf51 103 SMART SM00418 5 101 0.0012 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CXR48_RS16825 e45a0dbcc7cd6dda26008cdd3acd6afc 512 Pfam PF00535 Glycosyl transferase family 2 39 168 2.1E-27 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS16825 e45a0dbcc7cd6dda26008cdd3acd6afc 512 Gene3D G3DSA:3.90.550.10 32 334 5.9E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16825 e45a0dbcc7cd6dda26008cdd3acd6afc 512 SUPERFAMILY SSF53448 36 257 1.45E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS04915 a47f23b2a12695ad9742366c467223b3 61 Pfam PF14120 YhzD-like protein 1 61 3.1E-27 T 29-03-2018 IPR025544 YhzD-like protein CXR48_RS18690 9a98570c1bf802e4d47bac598db4afa5 280 SUPERFAMILY SSF51658 5 272 6.15E-68 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS18690 9a98570c1bf802e4d47bac598db4afa5 280 Gene3D G3DSA:3.20.20.150 1 278 1.9E-55 T 29-03-2018 CXR48_RS18690 9a98570c1bf802e4d47bac598db4afa5 280 Pfam PF01261 Xylose isomerase-like TIM barrel 20 225 1.7E-31 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CXR48_RS16655 4c0f2668a06135445c04245669f5eac5 74 Hamap MF_00167 Carbon storage regulator [csrA]. 1 68 20.493 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CXR48_RS16655 4c0f2668a06135445c04245669f5eac5 74 Pfam PF02599 Global regulator protein family 1 51 1.9E-25 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CXR48_RS16655 4c0f2668a06135445c04245669f5eac5 74 SUPERFAMILY SSF117130 1 55 3.53E-20 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CXR48_RS16655 4c0f2668a06135445c04245669f5eac5 74 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 66 2.1E-31 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CXR48_RS16655 4c0f2668a06135445c04245669f5eac5 74 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 2.0E-17 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CXR48_RS14770 006b9cab5a1beea28121b63d613d22df 46 ProDom PD014716 DEGQ ENZYME DEGRADATION SACQ REGULATORY REGULATION FACTOR 1 46 6.0E-18 T 29-03-2018 IPR012554 Degradation enzyme regulation protein DegQ GO:1900192 CXR48_RS14770 006b9cab5a1beea28121b63d613d22df 46 Pfam PF08181 DegQ (SacQ) family 3 46 3.4E-28 T 29-03-2018 IPR012554 Degradation enzyme regulation protein DegQ GO:1900192 CXR48_RS14725 db7b4e6befbadf4532680959252c226f 493 TIGRFAM TIGR00944 2a6301s04: multicomponent K+:H+antiporter 3 463 2.2E-210 T 29-03-2018 IPR004775 Na(+)/H(+) antiporter subunit D1 GO:0006812|GO:0015386|GO:0016021 CXR48_RS14725 db7b4e6befbadf4532680959252c226f 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 8.2E-17 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS14725 db7b4e6befbadf4532680959252c226f 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 8.2E-17 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS14725 db7b4e6befbadf4532680959252c226f 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 8.2E-17 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS14725 db7b4e6befbadf4532680959252c226f 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 8.2E-17 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS14725 db7b4e6befbadf4532680959252c226f 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 8.2E-17 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS14725 db7b4e6befbadf4532680959252c226f 493 Pfam PF00361 Proton-conducting membrane transporter 127 417 2.3E-48 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CXR48_RS03250 3eba851a0e0c75ac17162410716c7707 57 Pfam PF13076 Fur-regulated basic protein A 12 46 8.4E-11 T 29-03-2018 IPR025072 Fur-regulated basic protein A CXR48_RS16835 01d698f01f632d20356f3272734a281c 256 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 2 239 55.112 T 29-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 CXR48_RS16835 01d698f01f632d20356f3272734a281c 256 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 230 3.0E-72 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CXR48_RS16835 01d698f01f632d20356f3272734a281c 256 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 60 224 1.0E-59 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CXR48_RS17575 16c8674f4129a2dc5c4f00597176c20c 175 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 93 1.6E-32 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CXR48_RS17575 16c8674f4129a2dc5c4f00597176c20c 175 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 171 16.469 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CXR48_RS17575 16c8674f4129a2dc5c4f00597176c20c 175 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 14 81 1.5E-13 T 29-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CXR48_RS10225 2227cebec24548c6d4d27928f60c14d7 140 Pfam PF05105 Bacteriophage holin family 18 124 3.3E-28 T 29-03-2018 IPR006480 Bacteriophage holin family CXR48_RS10225 2227cebec24548c6d4d27928f60c14d7 140 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 10 135 8.0E-38 T 29-03-2018 IPR006480 Bacteriophage holin family CXR48_RS15790 9c2fc39d58c11da2450313d4a29f4bbb 270 SMART SM00062 37 264 5.8E-63 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS15790 9c2fc39d58c11da2450313d4a29f4bbb 270 Gene3D G3DSA:3.40.190.10 33 163 4.5E-22 T 29-03-2018 CXR48_RS15790 9c2fc39d58c11da2450313d4a29f4bbb 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 262 6.9E-46 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CXR48_RS15790 9c2fc39d58c11da2450313d4a29f4bbb 270 SUPERFAMILY SSF53850 37 265 1.27E-45 T 29-03-2018 CXR48_RS15790 9c2fc39d58c11da2450313d4a29f4bbb 270 Gene3D G3DSA:3.40.190.10 164 270 2.4E-13 T 29-03-2018 CXR48_RS03060 db496bb7413b865fb4ac12c68a3d95d4 56 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 55 16.701 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CXR48_RS03060 db496bb7413b865fb4ac12c68a3d95d4 56 Pfam PF02416 mttA/Hcf106 family 2 54 1.8E-23 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CXR48_RS03060 db496bb7413b865fb4ac12c68a3d95d4 56 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 1 45 4.5E-19 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CXR48_RS11795 3faa7de08427b14899fadc49c6c2bdeb 448 Gene3D G3DSA:3.40.640.10 84 336 1.1E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS11795 3faa7de08427b14899fadc49c6c2bdeb 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 50.029 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CXR48_RS11795 3faa7de08427b14899fadc49c6c2bdeb 448 Gene3D G3DSA:3.90.1150.10 337 446 5.8E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS11795 3faa7de08427b14899fadc49c6c2bdeb 448 PIRSF PIRSF006815 3 447 9.3E-188 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CXR48_RS11795 3faa7de08427b14899fadc49c6c2bdeb 448 Pfam PF02347 Glycine cleavage system P-protein 3 441 1.1E-168 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CXR48_RS11795 3faa7de08427b14899fadc49c6c2bdeb 448 SUPERFAMILY SSF53383 3 443 7.82E-121 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS11275 154d958f599424f1ca459355479bc99e 356 Pfam PF01594 AI-2E family transporter 17 345 3.5E-79 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CXR48_RS08400 4acb9d5c9d6462e534102d8881c5679f 151 Gene3D G3DSA:1.10.10.10 25 110 1.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08400 4acb9d5c9d6462e534102d8881c5679f 151 Gene3D G3DSA:1.10.287.100 111 147 8.5E-14 T 29-03-2018 CXR48_RS08400 4acb9d5c9d6462e534102d8881c5679f 151 SMART SM00347 29 129 2.5E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS08400 4acb9d5c9d6462e534102d8881c5679f 151 SUPERFAMILY SSF46785 8 144 5.96E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS08400 4acb9d5c9d6462e534102d8881c5679f 151 Pfam PF01047 MarR family 36 94 5.8E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS08400 4acb9d5c9d6462e534102d8881c5679f 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 2.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS08400 4acb9d5c9d6462e534102d8881c5679f 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 2.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS08400 4acb9d5c9d6462e534102d8881c5679f 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 2.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS08400 4acb9d5c9d6462e534102d8881c5679f 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 2.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS15920 1bbf8dabbc8d693f9c86d9a514455660 297 SUPERFAMILY SSF53850 26 295 1.33E-68 T 29-03-2018 CXR48_RS15920 1bbf8dabbc8d693f9c86d9a514455660 297 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 26 292 1.6E-61 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CXR48_RS15920 1bbf8dabbc8d693f9c86d9a514455660 297 Gene3D G3DSA:3.40.190.10 15 173 4.0E-33 T 29-03-2018 CXR48_RS15920 1bbf8dabbc8d693f9c86d9a514455660 297 Gene3D G3DSA:3.40.190.10 174 295 2.0E-23 T 29-03-2018 CXR48_RS17245 45d056f601ee630dc75bee669abed463 188 SUPERFAMILY SSF52499 7 186 1.44E-51 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS17245 45d056f601ee630dc75bee669abed463 188 PRINTS PR01398 Isochorismatase signature 89 111 3.0E-5 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS17245 45d056f601ee630dc75bee669abed463 188 PRINTS PR01398 Isochorismatase signature 163 180 3.0E-5 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS17245 45d056f601ee630dc75bee669abed463 188 PRINTS PR01398 Isochorismatase signature 145 163 3.0E-5 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CXR48_RS17245 45d056f601ee630dc75bee669abed463 188 Gene3D G3DSA:3.40.50.850 7 188 5.5E-47 T 29-03-2018 CXR48_RS17245 45d056f601ee630dc75bee669abed463 188 Pfam PF00857 Isochorismatase family 12 181 1.1E-41 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CXR48_RS18545 624452bf57261e6f265cd334453e0c3b 303 SUPERFAMILY SSF103481 41 141 1.7E-12 T 29-03-2018 CXR48_RS18545 624452bf57261e6f265cd334453e0c3b 303 Pfam PF00892 EamA-like transporter family 154 285 1.2E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS18545 624452bf57261e6f265cd334453e0c3b 303 Pfam PF00892 EamA-like transporter family 10 140 1.3E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS18545 624452bf57261e6f265cd334453e0c3b 303 SUPERFAMILY SSF103481 189 289 6.02E-12 T 29-03-2018 CXR48_RS06350 dbd4b6503d9b18249d65ed0f9213f00d 65 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 20 57 1.8E-10 T 29-03-2018 IPR010022 Protein of unknown function XkdX CXR48_RS06350 dbd4b6503d9b18249d65ed0f9213f00d 65 TIGRFAM TIGR01669 phage_XkdX: phage uncharacterized protein, XkdX family 14 57 2.9E-14 T 29-03-2018 IPR010022 Protein of unknown function XkdX CXR48_RS04680 bec5286ef04fa86f1ebf9affc9981010 504 Pfam PF05552 Conserved TM helix 285 332 1.7E-10 T 29-03-2018 IPR008910 Conserved TM helix CXR48_RS04680 bec5286ef04fa86f1ebf9affc9981010 504 Pfam PF05552 Conserved TM helix 383 421 5.0E-7 T 29-03-2018 IPR008910 Conserved TM helix CXR48_RS04680 bec5286ef04fa86f1ebf9affc9981010 504 Pfam PF05552 Conserved TM helix 5 49 7.4E-13 T 29-03-2018 IPR008910 Conserved TM helix CXR48_RS04680 bec5286ef04fa86f1ebf9affc9981010 504 Pfam PF05552 Conserved TM helix 190 237 1.3E-16 T 29-03-2018 IPR008910 Conserved TM helix CXR48_RS05630 f937a4516d0a805f5925e04e6247324d 305 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS05630 f937a4516d0a805f5925e04e6247324d 305 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 280 2.6E-9 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CXR48_RS05630 f937a4516d0a805f5925e04e6247324d 305 SMART SM00382 34 228 4.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS05630 f937a4516d0a805f5925e04e6247324d 305 SUPERFAMILY SSF52540 5 250 1.98E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05630 f937a4516d0a805f5925e04e6247324d 305 Gene3D G3DSA:3.40.50.300 2 300 6.5E-79 T 29-03-2018 CXR48_RS05630 f937a4516d0a805f5925e04e6247324d 305 Pfam PF00005 ABC transporter 26 178 3.8E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS06185 b68928f89a1113618a7ae00b01d4a9ee 196 Pfam PF06114 IrrE N-terminal-like domain 33 147 4.3E-18 T 29-03-2018 IPR010359 IrrE N-terminal-like domain CXR48_RS14785 bc1a4df34e42cfaf95d2974b042ed3d8 488 Gene3D G3DSA:3.20.140.10 9 389 1.4E-128 T 29-03-2018 CXR48_RS14785 bc1a4df34e42cfaf95d2974b042ed3d8 488 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 160 349 5.1E-13 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CXR48_RS14785 bc1a4df34e42cfaf95d2974b042ed3d8 488 SUPERFAMILY SSF51690 142 480 1.34E-130 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CXR48_RS14785 bc1a4df34e42cfaf95d2974b042ed3d8 488 PIRSF PIRSF000484 6 482 2.2E-155 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CXR48_RS14785 bc1a4df34e42cfaf95d2974b042ed3d8 488 SUPERFAMILY SSF54675 9 141 7.65E-50 T 29-03-2018 CXR48_RS14785 bc1a4df34e42cfaf95d2974b042ed3d8 488 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 12 467 2.1E-180 T 29-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CXR48_RS12535 2b760151916f5a652443761cb9beeef5 379 PIRSF PIRSF001434 1 379 2.8E-145 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CXR48_RS12535 2b760151916f5a652443761cb9beeef5 379 Gene3D G3DSA:3.40.640.10 1 245 6.8E-60 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS12535 2b760151916f5a652443761cb9beeef5 379 Gene3D G3DSA:3.90.1150.10 246 379 2.2E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS12535 2b760151916f5a652443761cb9beeef5 379 SUPERFAMILY SSF53383 12 377 4.03E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS12535 2b760151916f5a652443761cb9beeef5 379 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CXR48_RS12535 2b760151916f5a652443761cb9beeef5 379 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 4.8E-156 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CXR48_RS11685 7d1ed392a6c026ec9f572f807b8ea62a 135 Pfam PF03780 Asp23 family, cell envelope-related function 16 121 2.0E-35 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CXR48_RS19315 82f0dc9b2e184a42c3570ac691fd659b 443 SUPERFAMILY SSF103473 11 440 1.44E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS19315 82f0dc9b2e184a42c3570ac691fd659b 443 Gene3D G3DSA:1.20.1250.20 15 217 2.0E-32 T 29-03-2018 CXR48_RS19315 82f0dc9b2e184a42c3570ac691fd659b 443 Pfam PF00083 Sugar (and other) transporter 64 441 9.7E-32 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CXR48_RS19315 82f0dc9b2e184a42c3570ac691fd659b 443 Gene3D G3DSA:1.20.1250.20 237 443 1.0E-27 T 29-03-2018 CXR48_RS05350 f77f514d8dd5df35d98af460568bd33d 196 ProDom PD106196 YISN IG BH1722 18 185 3.0E-40 T 29-03-2018 IPR024488 Protein of unknown function DUF2777 CXR48_RS05350 f77f514d8dd5df35d98af460568bd33d 196 Pfam PF10949 Protein of unknown function (DUF2777) 19 187 2.4E-48 T 29-03-2018 IPR024488 Protein of unknown function DUF2777 CXR48_RS01985 bb72a12931b38af85800cd5b4abbf182 314 Gene3D G3DSA:3.40.50.1980 21 152 9.2E-30 T 29-03-2018 CXR48_RS01985 bb72a12931b38af85800cd5b4abbf182 314 Gene3D G3DSA:3.40.50.1980 153 314 1.9E-33 T 29-03-2018 CXR48_RS01985 bb72a12931b38af85800cd5b4abbf182 314 Pfam PF01497 Periplasmic binding protein 55 288 1.7E-38 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CXR48_RS01985 bb72a12931b38af85800cd5b4abbf182 314 SUPERFAMILY SSF53807 35 303 2.94E-67 T 29-03-2018 CXR48_RS12755 192aa266973ee09394fe2270882d00b3 518 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 6 493 1.1E-189 T 29-03-2018 IPR014249 Sporulation stage V protein B CXR48_RS12755 192aa266973ee09394fe2270882d00b3 518 PIRSF PIRSF038958 1 517 4.9E-193 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CXR48_RS12755 192aa266973ee09394fe2270882d00b3 518 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 360 500 1.2E-15 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CXR48_RS12755 192aa266973ee09394fe2270882d00b3 518 Pfam PF01943 Polysaccharide biosynthesis protein 6 308 5.0E-69 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CXR48_RS02280 411c8478fa561fe36798874b1f89ca2c 135 ProDom PD082409 MEMBRANE YVAD TRANSMEMBRANE 2 110 2.0E-32 T 29-03-2018 IPR020348 Uncharacterised protein family YvaD CXR48_RS02280 411c8478fa561fe36798874b1f89ca2c 135 Pfam PF17314 Family of unknown function (DUF5360) 5 129 3.3E-58 T 29-03-2018 IPR020348 Uncharacterised protein family YvaD CXR48_RS01930 bf5574a5da706e751a08b53b74628d80 478 Pfam PF12704 MacB-like periplasmic core domain 24 249 1.6E-10 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CXR48_RS01930 bf5574a5da706e751a08b53b74628d80 478 Pfam PF02687 FtsX-like permease family 341 470 1.2E-15 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CXR48_RS10910 5702da51332f5f85d65102efac7c7de6 256 SMART SM00257 207 253 1.2E-9 T 29-03-2018 IPR018392 LysM domain CXR48_RS10910 5702da51332f5f85d65102efac7c7de6 256 SUPERFAMILY SSF54106 206 253 1.96E-7 T 29-03-2018 IPR018392 LysM domain CXR48_RS10910 5702da51332f5f85d65102efac7c7de6 256 Gene3D G3DSA:3.10.350.10 204 254 4.6E-10 T 29-03-2018 CXR48_RS10910 5702da51332f5f85d65102efac7c7de6 256 Pfam PF01476 LysM domain 208 253 5.9E-9 T 29-03-2018 IPR018392 LysM domain CXR48_RS17555 7f6ccdf7ba39c9e9a6e3255b22401aea 285 SUPERFAMILY SSF51569 1 285 1.33E-105 T 29-03-2018 CXR48_RS17555 7f6ccdf7ba39c9e9a6e3255b22401aea 285 PIRSF PIRSF001359 1 285 1.2E-127 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS17555 7f6ccdf7ba39c9e9a6e3255b22401aea 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 9.2E-105 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS17555 7f6ccdf7ba39c9e9a6e3255b22401aea 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 7.8E-134 T 29-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CXR48_RS17555 7f6ccdf7ba39c9e9a6e3255b22401aea 285 Gene3D G3DSA:3.20.20.70 1 285 2.8E-106 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS17555 7f6ccdf7ba39c9e9a6e3255b22401aea 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 1.2E-118 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS17555 7f6ccdf7ba39c9e9a6e3255b22401aea 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS17555 7f6ccdf7ba39c9e9a6e3255b22401aea 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CXR48_RS15130 db664702417b003ad81615923db466a8 283 SUPERFAMILY SSF117396 2 269 3.27E-86 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CXR48_RS15130 db664702417b003ad81615923db466a8 283 Gene3D G3DSA:3.20.20.410 1 282 1.5E-82 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CXR48_RS15130 db664702417b003ad81615923db466a8 283 Pfam PF01904 Protein of unknown function DUF72 16 265 8.1E-60 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CXR48_RS16120 b80be44e28ab65e36c75c0362d92675c 558 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 15 549 1.4E-183 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CXR48_RS16120 b80be44e28ab65e36c75c0362d92675c 558 Pfam PF02652 L-lactate permease 16 549 8.1E-212 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CXR48_RS10165 7329c5d007be63da2025b193153ad3e4 202 Gene3D G3DSA:3.40.630.30 2 200 5.6E-23 T 29-03-2018 CXR48_RS10165 7329c5d007be63da2025b193153ad3e4 202 Pfam PF13302 Acetyltransferase (GNAT) domain 13 157 2.9E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS10165 7329c5d007be63da2025b193153ad3e4 202 SUPERFAMILY SSF55729 2 184 1.24E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS16275 a897385797009d4e08ca074145baf742 475 Gene3D G3DSA:1.10.287.1060 344 475 5.3E-6 T 29-03-2018 CXR48_RS16275 a897385797009d4e08ca074145baf742 475 Gene3D G3DSA:3.40.50.1820 10 297 2.4E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS16275 a897385797009d4e08ca074145baf742 475 SUPERFAMILY SSF53474 13 115 3.94E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS16275 a897385797009d4e08ca074145baf742 475 SUPERFAMILY SSF53474 142 272 3.94E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS14935 a6b773bdfcc9788ad6c426f20b95c7d4 213 Pfam PF06725 3D domain 119 180 8.3E-19 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CXR48_RS14935 a6b773bdfcc9788ad6c426f20b95c7d4 213 Gene3D G3DSA:2.40.40.10 19 194 1.0E-31 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CXR48_RS14935 a6b773bdfcc9788ad6c426f20b95c7d4 213 SUPERFAMILY SSF50685 119 161 1.33E-7 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CXR48_RS03685 54ef8eda7112346ca6ebe4d7a432a43c 235 Gene3D G3DSA:2.160.20.50 48 107 0.0012 T 29-03-2018 CXR48_RS03685 54ef8eda7112346ca6ebe4d7a432a43c 235 Pfam PF01391 Collagen triple helix repeat (20 copies) 59 95 1.9E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CXR48_RS12560 a16ef2ae09d78640d5f7669b51e469e8 238 Pfam PF07423 Protein of unknown function (DUF1510) 6 237 1.8E-72 T 29-03-2018 IPR009988 Protein of unknown function DUF1510 CXR48_RS12560 a16ef2ae09d78640d5f7669b51e469e8 238 Gene3D G3DSA:1.20.1110.10 17 150 9.4E-4 T 29-03-2018 CXR48_RS04370 4acde820d37af9394ca890890d6ddc5b 301 SUPERFAMILY SSF161098 81 266 1.44E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS04370 4acde820d37af9394ca890890d6ddc5b 301 Gene3D G3DSA:1.10.3720.10 23 296 4.4E-43 T 29-03-2018 CXR48_RS04370 4acde820d37af9394ca890890d6ddc5b 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 295 1.9E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS04370 4acde820d37af9394ca890890d6ddc5b 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 10 62 5.7E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CXR48_RS05365 bcf3d67bdc8b7c7ad0d3464712453a72 455 Pfam PF01554 MatE 252 413 6.4E-35 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS05365 bcf3d67bdc8b7c7ad0d3464712453a72 455 Pfam PF01554 MatE 27 187 8.1E-34 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS05365 bcf3d67bdc8b7c7ad0d3464712453a72 455 PIRSF PIRSF006603 10 455 1.2E-83 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS05365 bcf3d67bdc8b7c7ad0d3464712453a72 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 426 2.2E-62 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CXR48_RS16840 4441815c08198bc752fa25793b8fbb77 388 Gene3D G3DSA:3.40.50.2000 233 355 1.4E-5 T 29-03-2018 CXR48_RS16840 4441815c08198bc752fa25793b8fbb77 388 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 30 374 2.8E-81 T 29-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CXR48_RS16840 4441815c08198bc752fa25793b8fbb77 388 SUPERFAMILY SSF53756 55 377 6.28E-29 T 29-03-2018 CXR48_RS16445 6ddef5fcaf106c57feb11806a4ea505e 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CXR48_RS16445 6ddef5fcaf106c57feb11806a4ea505e 194 SUPERFAMILY SSF54211 1 86 3.54E-31 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS16445 6ddef5fcaf106c57feb11806a4ea505e 194 Gene3D G3DSA:3.30.230.40 1 88 1.3E-31 T 29-03-2018 CXR48_RS16445 6ddef5fcaf106c57feb11806a4ea505e 194 SUPERFAMILY SSF54211 87 178 6.2E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CXR48_RS16445 6ddef5fcaf106c57feb11806a4ea505e 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 41.577 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CXR48_RS16445 6ddef5fcaf106c57feb11806a4ea505e 194 Gene3D G3DSA:3.30.230.40 90 194 1.3E-34 T 29-03-2018 CXR48_RS16445 6ddef5fcaf106c57feb11806a4ea505e 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 5.2E-63 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CXR48_RS16445 6ddef5fcaf106c57feb11806a4ea505e 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 297 5.8E-35 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 SUPERFAMILY SSF55048 119 187 2.09E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 Pfam PF00698 Acyl transferase domain 4 286 1.2E-32 T 29-03-2018 IPR014043 Acyl transferase CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 280 5.7E-114 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 Gene3D G3DSA:3.40.366.10 1 172 8.7E-43 T 29-03-2018 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 Gene3D G3DSA:3.40.366.10 173 300 6.3E-21 T 29-03-2018 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 Gene3D G3DSA:3.20.20.70 307 584 5.3E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 SUPERFAMILY SSF51395 303 561 2.56E-24 T 29-03-2018 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 SUPERFAMILY SSF51395 191 257 2.56E-24 T 29-03-2018 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 SUPERFAMILY SSF52151 180 282 2.88E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 SUPERFAMILY SSF52151 1 115 2.88E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS08535 c9b407afa77a895debfc13afb67bec82 746 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 299 737 3.6E-207 T 29-03-2018 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CXR48_RS13345 a509565f8fb81dc1cf672ad098bcdae8 227 Pfam PF04172 LrgB-like family 10 223 3.3E-69 T 29-03-2018 IPR007300 CidB/LrgB family CXR48_RS13345 a509565f8fb81dc1cf672ad098bcdae8 227 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 1 226 31.508 T 29-03-2018 IPR024891 Antiholin-like protein LrgB CXR48_RS18920 908047529596e6fdbcab254170b410c6 249 SUPERFAMILY SSF54001 117 246 7.85E-16 T 29-03-2018 CXR48_RS18920 908047529596e6fdbcab254170b410c6 249 Gene3D G3DSA:3.90.1720.10 88 245 4.4E-10 T 29-03-2018 CXR48_RS15975 0022a92ff1b5138a2c079e823f00f146 252 Pfam PF08889 WbqC-like protein family 16 231 2.6E-74 T 29-03-2018 IPR014985 WbqC-like protein family CXR48_RS18205 3746d3e772ebc340d26801beea611ebf 165 Gene3D G3DSA:1.10.10.10 14 164 3.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18205 3746d3e772ebc340d26801beea611ebf 165 SUPERFAMILY SSF46785 34 163 1.46E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS18205 3746d3e772ebc340d26801beea611ebf 165 SMART SM00347 49 149 3.1E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS18205 3746d3e772ebc340d26801beea611ebf 165 Pfam PF01047 MarR family 56 114 4.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS18205 3746d3e772ebc340d26801beea611ebf 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 139 159 3.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS18205 3746d3e772ebc340d26801beea611ebf 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 105 3.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS18205 3746d3e772ebc340d26801beea611ebf 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 125 3.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS18205 3746d3e772ebc340d26801beea611ebf 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 88 122 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CXR48_RS19065 3f0e30e29c41f17969903afc67a0ed6e 137 Gene3D G3DSA:3.10.180.10 6 137 1.2E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS19065 3f0e30e29c41f17969903afc67a0ed6e 137 SUPERFAMILY SSF54593 12 133 2.42E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS19065 3f0e30e29c41f17969903afc67a0ed6e 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 129 6.6E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 49.144 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 SUPERFAMILY SSF52096 6 313 1.07E-98 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 1.3E-65 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 Gene3D G3DSA:3.90.226.10 10 312 3.5E-68 T 29-03-2018 CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 3.5E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 3.5E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 3.5E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 3.5E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 3.5E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 3.5E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13510 42e43fd6cfe734de44ff732a1c7cc923 325 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 1.1E-164 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 15 282 3.1E-137 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 SUPERFAMILY SSF52096 28 284 9.24E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 9.3E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 9.3E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 9.3E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 9.3E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 9.3E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 Pfam PF01039 Carboxyl transferase domain 63 242 3.1E-20 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 281 38.256 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CXR48_RS13515 a3e4e66bd72167489d8b063210e88f28 290 Gene3D G3DSA:3.90.226.10 15 286 1.0E-65 T 29-03-2018 CXR48_RS08110 e56953bc8551e2c767f0249d7a3832c9 447 Pfam PF02120 Flagellar hook-length control protein FliK 328 403 5.1E-19 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CXR48_RS14630 a15e0c7a16440b4f8bc3c01b967b94b9 86 Pfam PF08958 Domain of unknown function (DUF1871) 9 85 2.8E-35 T 29-03-2018 IPR015053 Protein of unknown function DUF1871 CXR48_RS14630 a15e0c7a16440b4f8bc3c01b967b94b9 86 SUPERFAMILY SSF116922 4 82 3.27E-28 T 29-03-2018 IPR023162 Apc36109-like domain CXR48_RS14630 a15e0c7a16440b4f8bc3c01b967b94b9 86 Gene3D G3DSA:1.10.340.20 4 79 1.0E-21 T 29-03-2018 CXR48_RS14630 a15e0c7a16440b4f8bc3c01b967b94b9 86 ProDom PD062625 YUGE 9 85 6.0E-28 T 29-03-2018 IPR015053 Protein of unknown function DUF1871 CXR48_RS00365 ef00f05cd76f545b81fd903da1f10a7d 100 PIRSF PIRSF011576 1 100 4.8E-57 T 29-03-2018 IPR012504 Sporulation protein YabP CXR48_RS00365 ef00f05cd76f545b81fd903da1f10a7d 100 Pfam PF07873 YabP family 17 82 4.5E-21 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC CXR48_RS00365 ef00f05cd76f545b81fd903da1f10a7d 100 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 17 100 1.8E-33 T 29-03-2018 IPR012504 Sporulation protein YabP CXR48_RS00365 ef00f05cd76f545b81fd903da1f10a7d 100 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 16 100 1.0E-42 T 29-03-2018 IPR012504 Sporulation protein YabP CXR48_RS15370 af1549d0137b7874f1c81505b70d2b55 85 Gene3D G3DSA:1.20.1260.10 2 85 8.1E-8 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS15465 5ac4e6f844085b8518a274c0ae5abd8c 61 Pfam PF13113 Protein of unknown function (DUF3970) 2 54 8.1E-27 T 29-03-2018 IPR025088 Protein of unknown function DUF3970 CXR48_RS19010 c8af4006058ff63882ed04c3d86e691a 264 SMART SM00849 13 218 2.8E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS19010 c8af4006058ff63882ed04c3d86e691a 264 Gene3D G3DSA:3.60.15.10 9 257 3.8E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS19010 c8af4006058ff63882ed04c3d86e691a 264 Pfam PF00753 Metallo-beta-lactamase superfamily 12 218 7.8E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS19010 c8af4006058ff63882ed04c3d86e691a 264 SUPERFAMILY SSF56281 7 232 2.23E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS19150 2259280018351bfb222984c81f1db5d4 161 Gene3D G3DSA:1.20.1260.10 1 137 2.8E-7 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS19150 2259280018351bfb222984c81f1db5d4 161 Pfam PF07875 Coat F domain 83 141 9.3E-19 T 29-03-2018 IPR012851 Spore coat protein CotF-like CXR48_RS12635 6d8714c250ed857e7a2d7e50e00cee5a 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 213 4.5E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS12635 6d8714c250ed857e7a2d7e50e00cee5a 216 Gene3D G3DSA:1.10.3720.10 2 216 5.5E-48 T 29-03-2018 CXR48_RS12635 6d8714c250ed857e7a2d7e50e00cee5a 216 SUPERFAMILY SSF161098 12 213 5.23E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS12635 6d8714c250ed857e7a2d7e50e00cee5a 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 107 1.6E-29 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CXR48_RS00635 8e4e0564f58b1c575036c30bd9b94717 249 Gene3D G3DSA:3.40.1280.10 77 248 2.2E-47 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CXR48_RS00635 8e4e0564f58b1c575036c30bd9b94717 249 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 81 8.7E-22 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CXR48_RS00635 8e4e0564f58b1c575036c30bd9b94717 249 Gene3D G3DSA:3.30.1330.30 1 76 6.2E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CXR48_RS00635 8e4e0564f58b1c575036c30bd9b94717 249 SUPERFAMILY SSF55315 2 78 4.59E-19 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CXR48_RS00635 8e4e0564f58b1c575036c30bd9b94717 249 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 244 9.2E-93 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CXR48_RS00635 8e4e0564f58b1c575036c30bd9b94717 249 SMART SM00967 7 81 4.8E-20 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CXR48_RS00635 8e4e0564f58b1c575036c30bd9b94717 249 Pfam PF00588 SpoU rRNA Methylase family 98 238 4.1E-39 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CXR48_RS00635 8e4e0564f58b1c575036c30bd9b94717 249 SUPERFAMILY SSF75217 69 245 1.05E-48 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CXR48_RS07540 b1d0dca20370ddda52582824f54ba4e0 539 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 11 537 2.1E-193 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CXR48_RS07540 b1d0dca20370ddda52582824f54ba4e0 539 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 539 31.851 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CXR48_RS07540 b1d0dca20370ddda52582824f54ba4e0 539 PIRSF PIRSF012535 1 539 2.7E-224 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CXR48_RS07540 b1d0dca20370ddda52582824f54ba4e0 539 Pfam PF10079 Bacillithiol biosynthesis BshC 1 536 7.1E-173 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CXR48_RS14145 7b4aaeb1ba5971cc3dc9853676defcb2 80 Pfam PF10763 Protein of unknown function (DUF2584) 1 80 2.2E-37 T 29-03-2018 IPR019699 Protein of unknown function DUF2584 CXR48_RS14145 7b4aaeb1ba5971cc3dc9853676defcb2 80 SUPERFAMILY SSF88697 1 80 3.23E-31 T 29-03-2018 IPR015947 PUA-like domain CXR48_RS14145 7b4aaeb1ba5971cc3dc9853676defcb2 80 Gene3D G3DSA:2.40.240.20 2 76 5.8E-35 T 29-03-2018 CXR48_RS14110 2961f37e0b8c6e7184412e0f2148e038 359 Pfam PF10776 Protein of unknown function (DUF2600) 20 348 1.7E-151 T 29-03-2018 IPR019712 Protein of unknown function DUF2600 KEGG: 00909+4.2.3.13|MetaCyc: PWY-5773|MetaCyc: PWY-5828 CXR48_RS17505 426f21e8db2a1d4f7e95d240aed2ff48 127 SUPERFAMILY SSF54593 1 126 5.5E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS17505 426f21e8db2a1d4f7e95d240aed2ff48 127 Gene3D G3DSA:3.10.180.10 2 127 3.9E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS17505 426f21e8db2a1d4f7e95d240aed2ff48 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 5.3E-22 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS05210 58e14acc9ca400c4975b553ef5341c95 105 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 102 23.043 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CXR48_RS05210 58e14acc9ca400c4975b553ef5341c95 105 SUPERFAMILY SSF117782 1 103 1.09E-32 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CXR48_RS05210 58e14acc9ca400c4975b553ef5341c95 105 Pfam PF01906 Putative heavy-metal-binding 1 101 2.0E-33 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CXR48_RS05210 58e14acc9ca400c4975b553ef5341c95 105 Gene3D G3DSA:3.30.110.70 1 102 8.3E-30 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CXR48_RS05400 d9a88bdd0ab69f13ea832043a9ff321d 146 Pfam PF13673 Acetyltransferase (GNAT) domain 37 141 9.5E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS05400 d9a88bdd0ab69f13ea832043a9ff321d 146 SUPERFAMILY SSF55729 1 145 7.02E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS05400 d9a88bdd0ab69f13ea832043a9ff321d 146 Gene3D G3DSA:3.40.630.30 1 146 3.9E-22 T 29-03-2018 CXR48_RS08470 849a87241b573bca23bf54d5366520bc 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 8.0E-33 T 29-03-2018 IPR007347 Sporulation stage V, protein S CXR48_RS08470 849a87241b573bca23bf54d5366520bc 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 2.2E-40 T 29-03-2018 IPR007347 Sporulation stage V, protein S CXR48_RS15895 f636dcd5ab10178ba81b057b61073f9a 305 Gene3D G3DSA:3.40.190.10 185 303 3.3E-22 T 29-03-2018 CXR48_RS15895 f636dcd5ab10178ba81b057b61073f9a 305 SUPERFAMILY SSF53850 34 303 7.51E-65 T 29-03-2018 CXR48_RS15895 f636dcd5ab10178ba81b057b61073f9a 305 Gene3D G3DSA:3.40.190.10 23 184 1.1E-31 T 29-03-2018 CXR48_RS15895 f636dcd5ab10178ba81b057b61073f9a 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 34 300 7.7E-55 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CXR48_RS11430 2be168c271dc3cd0cf998d28f62c3d41 308 Pfam PF12706 Beta-lactamase superfamily domain 201 270 2.0E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11430 2be168c271dc3cd0cf998d28f62c3d41 308 Pfam PF12706 Beta-lactamase superfamily domain 35 151 1.2E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11430 2be168c271dc3cd0cf998d28f62c3d41 308 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 41.888 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CXR48_RS11430 2be168c271dc3cd0cf998d28f62c3d41 308 SUPERFAMILY SSF56281 2 305 1.11E-87 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11430 2be168c271dc3cd0cf998d28f62c3d41 308 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 304 3.3E-120 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CXR48_RS11430 2be168c271dc3cd0cf998d28f62c3d41 308 Gene3D G3DSA:3.60.15.10 1 308 2.1E-66 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11220 4d7c74d2b4f83f20dbc4582474bb8fc6 306 Pfam PF00248 Aldo/keto reductase family 15 295 5.2E-66 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS11220 4d7c74d2b4f83f20dbc4582474bb8fc6 306 SUPERFAMILY SSF51430 1 298 1.31E-80 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS11220 4d7c74d2b4f83f20dbc4582474bb8fc6 306 Gene3D G3DSA:3.20.20.100 1 296 4.7E-83 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CXR48_RS11220 4d7c74d2b4f83f20dbc4582474bb8fc6 306 PRINTS PR00069 Aldo-keto reductase signature 103 121 1.9E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS11220 4d7c74d2b4f83f20dbc4582474bb8fc6 306 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.9E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS11220 4d7c74d2b4f83f20dbc4582474bb8fc6 306 PRINTS PR00069 Aldo-keto reductase signature 134 151 1.9E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CXR48_RS18005 b5cc77ef27150ab1d1f052e010081469 460 SUPERFAMILY SSF55604 6 80 3.01E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS18005 b5cc77ef27150ab1d1f052e010081469 460 Pfam PF00367 phosphotransferase system, EIIB 8 40 1.3E-13 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS18005 b5cc77ef27150ab1d1f052e010081469 460 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CXR48_RS18005 b5cc77ef27150ab1d1f052e010081469 460 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 28 111 7.0E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS18005 b5cc77ef27150ab1d1f052e010081469 460 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 153 439 1.2E-92 T 29-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS18005 b5cc77ef27150ab1d1f052e010081469 460 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 450 3.5E-191 T 29-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 CXR48_RS18005 b5cc77ef27150ab1d1f052e010081469 460 Gene3D G3DSA:3.30.1360.60 4 81 2.0E-26 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CXR48_RS18005 b5cc77ef27150ab1d1f052e010081469 460 Pfam PF02378 Phosphotransferase system, EIIC 110 394 4.2E-49 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CXR48_RS14920 3da0be41927995488a3e043b2f65769e 442 Pfam PF03553 Na+/H+ antiporter family 150 436 1.9E-65 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CXR48_RS14920 3da0be41927995488a3e043b2f65769e 442 Pfam PF13726 Na+-H+ antiporter family 2 88 1.2E-32 T 29-03-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal CXR48_RS07055 4f5cbb210e660e50b6fcc1cb0ba9a308 339 Gene3D G3DSA:3.40.50.720 1 245 1.3E-60 T 29-03-2018 CXR48_RS07055 4f5cbb210e660e50b6fcc1cb0ba9a308 339 Pfam PF00899 ThiF family 5 240 9.6E-59 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CXR48_RS07055 4f5cbb210e660e50b6fcc1cb0ba9a308 339 SUPERFAMILY SSF69572 2 329 2.75E-82 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CXR48_RS04170 3755f81a6827476ad731e6e747e3b0a3 327 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 162 2.4E-26 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CXR48_RS17055 e667021ba829da9aaca0b17fbce14dd7 181 Pfam PF03358 NADPH-dependent FMN reductase 1 145 5.6E-22 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CXR48_RS17055 e667021ba829da9aaca0b17fbce14dd7 181 Gene3D G3DSA:3.40.50.360 1 181 1.1E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS17055 e667021ba829da9aaca0b17fbce14dd7 181 SUPERFAMILY SSF52218 1 178 2.17E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS02595 5f3852ab0626d74bc8ddb3aeb2488c19 160 Pfam PF13686 DsrE/DsrF/DrsH-like family 5 159 5.7E-68 T 29-03-2018 IPR032836 DsrE2-like family CXR48_RS02595 5f3852ab0626d74bc8ddb3aeb2488c19 160 SUPERFAMILY SSF75169 6 52 2.75E-22 T 29-03-2018 IPR027396 DsrEFH-like CXR48_RS02595 5f3852ab0626d74bc8ddb3aeb2488c19 160 SUPERFAMILY SSF75169 102 158 2.75E-22 T 29-03-2018 IPR027396 DsrEFH-like CXR48_RS02595 5f3852ab0626d74bc8ddb3aeb2488c19 160 Gene3D G3DSA:3.40.1260.10 1 160 9.2E-54 T 29-03-2018 CXR48_RS06115 12a7fb2a7d8f76bb723dcb91cd363f1a 243 Pfam PF12730 ABC-2 family transporter protein 4 176 5.6E-19 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CXR48_RS01330 497485dacbf77c56dd6eafb65f802aef 322 Pfam PF12368 Rhodanase C-terminal 222 288 8.5E-14 T 29-03-2018 IPR022111 Rhodanase, C-terminal CXR48_RS01330 497485dacbf77c56dd6eafb65f802aef 322 Pfam PF00581 Rhodanese-like domain 117 210 5.7E-12 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS01330 497485dacbf77c56dd6eafb65f802aef 322 Hamap MF_00469 UPF0176 protein YceA [yceA]. 3 267 40.443 T 29-03-2018 IPR020936 Uncharacterised protein family UPF0176 CXR48_RS01330 497485dacbf77c56dd6eafb65f802aef 322 Gene3D G3DSA:3.40.250.10 109 230 1.6E-25 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS01330 497485dacbf77c56dd6eafb65f802aef 322 SMART SM00450 115 216 2.5E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS01330 497485dacbf77c56dd6eafb65f802aef 322 SUPERFAMILY SSF52821 88 247 1.26E-34 T 29-03-2018 IPR001763 Rhodanese-like domain CXR48_RS11015 811215aa5df12364499464587e81c276 29 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 6 28 1.6E-10 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS11015 811215aa5df12364499464587e81c276 29 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 3 28 1.1E-12 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS18165 afde812d074b122bf19fcc0d5b3bf555 226 Pfam PF04172 LrgB-like family 11 223 1.3E-71 T 29-03-2018 IPR007300 CidB/LrgB family CXR48_RS18165 afde812d074b122bf19fcc0d5b3bf555 226 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 2 223 5.1E-95 T 29-03-2018 IPR005261 Conserved hypothetical protein CHP00659 CXR48_RS10240 881bada32fdb2b53bcb1ad072fde5776 607 Pfam PF10651 Domain of unknown function (DUF2479) 7 145 8.6E-30 T 29-03-2018 IPR018913 Domain of unknown function DUF2479 CXR48_RS04865 7934d923a01292a53bf2a23a65a8fbf1 377 Pfam PF04286 Protein of unknown function (DUF445) 12 376 1.4E-82 T 29-03-2018 IPR007383 Protein of unknown function DUF445 CXR48_RS04865 7934d923a01292a53bf2a23a65a8fbf1 377 PIRSF PIRSF032178 1 377 3.0E-137 T 29-03-2018 IPR016991 Protein of unknown function UCP032178 CXR48_RS12885 4b0e231352f0de30b552256d2e15c511 267 SUPERFAMILY SSF51261 154 261 1.33E-8 T 29-03-2018 IPR011055 Duplicated hybrid motif CXR48_RS12885 4b0e231352f0de30b552256d2e15c511 267 Pfam PF01551 Peptidase family M23 169 259 4.4E-12 T 29-03-2018 IPR016047 Peptidase M23 CXR48_RS12885 4b0e231352f0de30b552256d2e15c511 267 Gene3D G3DSA:2.70.70.10 2 265 5.1E-14 T 29-03-2018 CXR48_RS04850 87ea4d520f7296306dd1af779eb33b60 71 Pfam PF17277 Family of unknown function (DUF5342) 4 71 5.8E-30 T 29-03-2018 IPR017263 Uncharacterised conserved protein UCP037692 CXR48_RS04850 87ea4d520f7296306dd1af779eb33b60 71 ProDom PD056348 YHEE BH1143 4 71 3.0E-25 T 29-03-2018 IPR017263 Uncharacterised conserved protein UCP037692 CXR48_RS04850 87ea4d520f7296306dd1af779eb33b60 71 PIRSF PIRSF037692 4 71 1.6E-32 T 29-03-2018 IPR017263 Uncharacterised conserved protein UCP037692 CXR48_RS09590 2171eeb4a605d45ad0db77147c30be8b 296 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 132 150 2.5E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS09590 2171eeb4a605d45ad0db77147c30be8b 296 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 60 78 2.5E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CXR48_RS09590 2171eeb4a605d45ad0db77147c30be8b 296 SMART SM00382 56 202 0.0017 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS09590 2171eeb4a605d45ad0db77147c30be8b 296 Pfam PF07728 AAA domain (dynein-related subfamily) 59 196 2.7E-28 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CXR48_RS09590 2171eeb4a605d45ad0db77147c30be8b 296 SUPERFAMILY SSF52540 45 279 8.62E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS09590 2171eeb4a605d45ad0db77147c30be8b 296 Gene3D G3DSA:3.40.50.300 42 202 1.1E-28 T 29-03-2018 CXR48_RS00335 3da4b035256af37b4b95ae10fdd02b6d 76 ProDom PD057826 YABK 4 76 2.0E-32 T 29-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 CXR48_RS00335 3da4b035256af37b4b95ae10fdd02b6d 76 Pfam PF10955 Protein of unknown function (DUF2757) 1 76 6.8E-35 T 29-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 CXR48_RS09725 9e6be2e198351689a0d80bf8fabc13b8 272 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 120 249 2.0E-44 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CXR48_RS09725 9e6be2e198351689a0d80bf8fabc13b8 272 Gene3D G3DSA:3.30.1380.10 85 261 1.0E-38 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CXR48_RS09725 9e6be2e198351689a0d80bf8fabc13b8 272 SUPERFAMILY SSF55166 106 257 9.68E-42 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CXR48_RS11850 28935dd6625d02f26bf7bcb927ab97bc 125 ProDom PD078266 COMPETENCE COMGG LATE MACHINERY OPERON DNA THE PART PRECURSOR PROBABLY 1 124 2.0E-26 T 29-03-2018 IPR020372 Competence operon G protein 7, ComGG CXR48_RS11850 28935dd6625d02f26bf7bcb927ab97bc 125 Pfam PF14173 ComG operon protein 7 30 124 7.2E-21 T 29-03-2018 IPR020372 Competence operon G protein 7, ComGG CXR48_RS06910 22a34efa4981bc2672d8ddf27fb186be 710 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 326 7.6E-24 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS06910 22a34efa4981bc2672d8ddf27fb186be 710 SUPERFAMILY SSF56601 342 704 1.77E-67 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CXR48_RS06910 22a34efa4981bc2672d8ddf27fb186be 710 Gene3D G3DSA:3.90.1310.10 32 341 5.2E-29 T 29-03-2018 CXR48_RS06910 22a34efa4981bc2672d8ddf27fb186be 710 Gene3D G3DSA:3.40.710.10 342 710 6.0E-76 T 29-03-2018 CXR48_RS06910 22a34efa4981bc2672d8ddf27fb186be 710 SUPERFAMILY SSF56519 212 341 1.44E-29 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS06910 22a34efa4981bc2672d8ddf27fb186be 710 SUPERFAMILY SSF56519 59 121 1.44E-29 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CXR48_RS06910 22a34efa4981bc2672d8ddf27fb186be 710 Pfam PF00905 Penicillin binding protein transpeptidase domain 372 695 2.5E-77 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CXR48_RS11915 fe6bffd5131f1d77a190ce8684a8570f 212 SMART SM00849 12 191 1.4E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11915 fe6bffd5131f1d77a190ce8684a8570f 212 SUPERFAMILY SSF56281 10 208 9.83E-50 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11915 fe6bffd5131f1d77a190ce8684a8570f 212 Pfam PF00753 Metallo-beta-lactamase superfamily 9 191 9.6E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS11915 fe6bffd5131f1d77a190ce8684a8570f 212 Gene3D G3DSA:3.60.15.10 1 211 1.0E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS02625 26e8fc7003e330af9cb4a59a73be96f7 226 SUPERFAMILY SSF53681 116 221 9.32E-21 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02625 26e8fc7003e330af9cb4a59a73be96f7 226 SUPERFAMILY SSF53681 1 112 7.68E-28 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02625 26e8fc7003e330af9cb4a59a73be96f7 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 220 6.3E-36 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CXR48_RS02625 26e8fc7003e330af9cb4a59a73be96f7 226 Gene3D G3DSA:3.40.50.1860 1 114 2.4E-26 T 29-03-2018 CXR48_RS02625 26e8fc7003e330af9cb4a59a73be96f7 226 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 87 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS02625 26e8fc7003e330af9cb4a59a73be96f7 226 Gene3D G3DSA:3.40.50.1860 115 208 1.3E-15 T 29-03-2018 CXR48_RS02625 26e8fc7003e330af9cb4a59a73be96f7 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 217 3.7E-40 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CXR48_RS18640 a76dfe32d2f3eabb9c9a6bf623529caf 128 Pfam PF10359 RNA pol II promoter Fmp27 protein domain 13 111 1.2E-5 T 29-03-2018 IPR019449 FMP27, WPPW domain CXR48_RS18640 a76dfe32d2f3eabb9c9a6bf623529caf 128 Gene3D G3DSA:1.20.5.320 20 125 1.2E-6 T 29-03-2018 CXR48_RS13260 47ccf295101fca52112b8ebdd72b84b6 598 Pfam PF02554 Carbon starvation protein CstA 1 366 6.3E-146 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CXR48_RS13260 47ccf295101fca52112b8ebdd72b84b6 598 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 416 537 1.6E-29 T 29-03-2018 IPR025299 CstA, C-terminal domain CXR48_RS04795 455e21d4b788ccd204e6eea98183b790 247 SUPERFAMILY SSF52467 2 244 9.15E-74 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS04795 455e21d4b788ccd204e6eea98183b790 247 Gene3D G3DSA:3.40.50.1220 1 246 4.2E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CXR48_RS04795 455e21d4b788ccd204e6eea98183b790 247 Pfam PF02146 Sir2 family 19 198 1.4E-53 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 CXR48_RS04795 455e21d4b788ccd204e6eea98183b790 247 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 3 244 58.239 T 29-03-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 CXR48_RS01490 eed80b227bc2a35655cef889f62dfcff 331 Pfam PF11611 Domain of unknown function (DUF4352) 50 128 4.9E-19 T 29-03-2018 IPR029051 Domain of unknown function DUF4352 CXR48_RS01490 eed80b227bc2a35655cef889f62dfcff 331 Gene3D G3DSA:2.60.40.1240 27 155 4.8E-15 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CXR48_RS01490 eed80b227bc2a35655cef889f62dfcff 331 Pfam PF17118 Domain of unknown function (DUF5105) 147 327 2.0E-43 T 29-03-2018 IPR031343 Domain of unknown function DUF5105 CXR48_RS17160 cc75ee904a321d02d3dcc0cf3036e034 924 Pfam PF00176 SNF2 family N-terminal domain 461 734 1.0E-57 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CXR48_RS17160 cc75ee904a321d02d3dcc0cf3036e034 924 SMART SM00487 446 636 1.0E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CXR48_RS17160 cc75ee904a321d02d3dcc0cf3036e034 924 SUPERFAMILY SSF52540 669 920 5.32E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS17160 cc75ee904a321d02d3dcc0cf3036e034 924 Gene3D G3DSA:3.40.50.300 734 900 4.0E-37 T 29-03-2018 CXR48_RS17160 cc75ee904a321d02d3dcc0cf3036e034 924 SUPERFAMILY SSF52540 436 664 5.76E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS17160 cc75ee904a321d02d3dcc0cf3036e034 924 Pfam PF12419 SNF2 Helicase protein 267 392 1.8E-34 T 29-03-2018 IPR022138 Helicase SWF/SNF-related CXR48_RS17160 cc75ee904a321d02d3dcc0cf3036e034 924 SMART SM00490 779 862 6.7E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS17160 cc75ee904a321d02d3dcc0cf3036e034 924 Pfam PF00271 Helicase conserved C-terminal domain 751 862 1.3E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CXR48_RS17160 cc75ee904a321d02d3dcc0cf3036e034 924 Gene3D G3DSA:3.40.50.10810 451 665 5.6E-53 T 29-03-2018 CXR48_RS15420 3f4a4f468b69989487da23636ae3bf39 593 Pfam PF01432 Peptidase family M3 199 536 2.8E-22 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CXR48_RS15420 3f4a4f468b69989487da23636ae3bf39 593 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 9 591 1.7E-200 T 29-03-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 CXR48_RS15420 3f4a4f468b69989487da23636ae3bf39 593 Gene3D G3DSA:1.10.1370.10 82 587 3.3E-17 T 29-03-2018 CXR48_RS15420 3f4a4f468b69989487da23636ae3bf39 593 Pfam PF08439 Oligopeptidase F 117 183 1.2E-11 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CXR48_RS15420 3f4a4f468b69989487da23636ae3bf39 593 SUPERFAMILY SSF55486 8 574 1.47E-95 T 29-03-2018 CXR48_RS10200 2198c6dd2bcac5d6c6277deac83915f9 230 Gene3D G3DSA:2.60.40.1240 100 227 1.0E-12 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CXR48_RS06840 95529753a0d2c5cfe241df631d163537 446 PIRSF PIRSF038958 1 436 1.9E-75 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CXR48_RS06840 95529753a0d2c5cfe241df631d163537 446 Pfam PF01943 Polysaccharide biosynthesis protein 5 294 1.6E-26 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CXR48_RS06840 95529753a0d2c5cfe241df631d163537 446 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 346 435 2.0E-8 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CXR48_RS14405 2f59ff9554ec006e5229d5638302d519 176 Gene3D G3DSA:2.40.50.140 94 176 4.3E-19 T 29-03-2018 CXR48_RS03475 b7979297103ba46c0cedb6d3b6801270 239 SUPERFAMILY SSF75625 1 238 4.97E-81 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS03475 b7979297103ba46c0cedb6d3b6801270 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.734 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS03475 b7979297103ba46c0cedb6d3b6801270 239 Gene3D G3DSA:3.30.70.980 80 174 3.6E-26 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS03475 b7979297103ba46c0cedb6d3b6801270 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 2.8E-71 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS03475 b7979297103ba46c0cedb6d3b6801270 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 57.793 T 29-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN CXR48_RS03475 b7979297103ba46c0cedb6d3b6801270 239 Gene3D G3DSA:1.10.10.200 2 76 7.7E-27 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CXR48_RS03475 b7979297103ba46c0cedb6d3b6801270 239 Pfam PF01709 Transcriptional regulator 4 235 1.9E-81 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS03475 b7979297103ba46c0cedb6d3b6801270 239 Gene3D G3DSA:3.30.70.980 175 239 1.6E-10 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CXR48_RS10255 7293377e5a7435ff9f5a0d6f0da5a9ef 279 Pfam PF05709 Phage tail protein 31 279 4.1E-36 T 29-03-2018 IPR008841 Siphovirus-type tail component CXR48_RS02855 5e92edbfe363bb88d9bcd5a990fbffcb 152 Gene3D G3DSA:1.10.287.900 2 39 2.5E-9 T 29-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 CXR48_RS02855 5e92edbfe363bb88d9bcd5a990fbffcb 152 SUPERFAMILY SSF55729 1 145 4.49E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS02855 5e92edbfe363bb88d9bcd5a990fbffcb 152 Pfam PF00583 Acetyltransferase (GNAT) family 28 134 4.4E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS02855 5e92edbfe363bb88d9bcd5a990fbffcb 152 Gene3D G3DSA:3.40.630.30 43 150 1.4E-20 T 29-03-2018 CXR48_RS11715 632d4a6c05f7a629ee9897d97dbd4293 402 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 81 395 2.6E-106 T 29-03-2018 IPR014194 Sporulation stage III, protein AE CXR48_RS11715 632d4a6c05f7a629ee9897d97dbd4293 402 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 1 395 7.8E-155 T 29-03-2018 IPR014194 Sporulation stage III, protein AE CXR48_RS01185 3b4b9edcfd80a4f44c83668f5941d5ff 231 Gene3D G3DSA:3.40.50.1820 3 231 8.0E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS01185 3b4b9edcfd80a4f44c83668f5941d5ff 231 Pfam PF00975 Thioesterase domain 3 228 2.8E-35 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CXR48_RS01185 3b4b9edcfd80a4f44c83668f5941d5ff 231 SUPERFAMILY SSF53474 4 230 2.83E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS11905 27d3b65b4e74d1bd8646e542c12a05f9 126 SUPERFAMILY SSF52833 4 115 7.24E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS11905 27d3b65b4e74d1bd8646e542c12a05f9 126 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 5 115 5.8E-41 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CXR48_RS11905 27d3b65b4e74d1bd8646e542c12a05f9 126 Pfam PF03960 ArsC family 7 112 1.0E-19 T 29-03-2018 IPR006660 Arsenate reductase-like CXR48_RS11905 27d3b65b4e74d1bd8646e542c12a05f9 126 Gene3D G3DSA:3.40.30.10 3 125 2.5E-32 T 29-03-2018 CXR48_RS19395 5ee0adedb66a3a91736d95204f518648 253 SUPERFAMILY SSF52540 2 251 3.0E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS19395 5ee0adedb66a3a91736d95204f518648 253 Gene3D G3DSA:3.40.50.300 1 252 1.8E-66 T 29-03-2018 CXR48_RS19395 5ee0adedb66a3a91736d95204f518648 253 PIRSF PIRSF009320 2 77 2.1E-15 T 29-03-2018 CXR48_RS19395 5ee0adedb66a3a91736d95204f518648 253 PIRSF PIRSF009320 90 250 1.6E-7 T 29-03-2018 CXR48_RS19395 5ee0adedb66a3a91736d95204f518648 253 PRINTS PR00091 Nitrogenase component II signature 31 46 8.7E-5 T 29-03-2018 CXR48_RS19395 5ee0adedb66a3a91736d95204f518648 253 PRINTS PR00091 Nitrogenase component II signature 9 22 8.7E-5 T 29-03-2018 CXR48_RS19395 5ee0adedb66a3a91736d95204f518648 253 Pfam PF13614 AAA domain 2 178 2.6E-73 T 29-03-2018 IPR025669 AAA domain CXR48_RS11420 7d2985032e20b14ffcbc27cc7ace871c 257 SUPERFAMILY SSF53474 12 239 3.93E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS11420 7d2985032e20b14ffcbc27cc7ace871c 257 Gene3D G3DSA:3.40.50.1820 2 248 9.0E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS11420 7d2985032e20b14ffcbc27cc7ace871c 257 Pfam PF00561 alpha/beta hydrolase fold 30 133 6.7E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CXR48_RS03240 50259b5ad6e426e5718dfb6d0fd6f4b5 440 PIRSF PIRSF005353 1 440 3.9E-173 T 29-03-2018 IPR026033 Purine permease PbuG-like CXR48_RS03240 50259b5ad6e426e5718dfb6d0fd6f4b5 440 Pfam PF00860 Permease family 16 402 1.5E-47 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS04235 40847e550abdec723fc8277d2470291c 294 ProDom PD128250 YGXA BH0953 1 279 3.0E-141 T 29-03-2018 CXR48_RS04235 40847e550abdec723fc8277d2470291c 294 Gene3D G3DSA:1.10.10.10 232 284 6.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04235 40847e550abdec723fc8277d2470291c 294 Pfam PF14540 Nucleotidyltransferase-like 1 118 1.8E-48 T 29-03-2018 IPR029348 Nucleotidyltransferase-like domain CXR48_RS04235 40847e550abdec723fc8277d2470291c 294 Gene3D G3DSA:3.30.460.10 1 114 2.7E-45 T 29-03-2018 CXR48_RS04235 40847e550abdec723fc8277d2470291c 294 Gene3D G3DSA:1.20.120.330 118 231 6.9E-45 T 29-03-2018 CXR48_RS04760 39fcd0865ab1823e58ec0cb1d56700e2 414 SMART SM00825 Beta-ketoacyl synthase 11 410 1.7E-11 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CXR48_RS04760 39fcd0865ab1823e58ec0cb1d56700e2 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 251 3.2E-34 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CXR48_RS04760 39fcd0865ab1823e58ec0cb1d56700e2 414 SUPERFAMILY SSF53901 10 256 8.51E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS04760 39fcd0865ab1823e58ec0cb1d56700e2 414 Gene3D G3DSA:3.40.47.10 268 413 1.1E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS04760 39fcd0865ab1823e58ec0cb1d56700e2 414 SUPERFAMILY SSF53901 220 409 1.34E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS04760 39fcd0865ab1823e58ec0cb1d56700e2 414 Gene3D G3DSA:3.40.47.10 1 262 5.2E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CXR48_RS04760 39fcd0865ab1823e58ec0cb1d56700e2 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 368 1.9E-26 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CXR48_RS00015 e0bd4960fbfcd779597c359ccdaf7698 71 SUPERFAMILY SSF55174 4 67 6.92E-19 T 29-03-2018 CXR48_RS00015 e0bd4960fbfcd779597c359ccdaf7698 71 Pfam PF13275 S4 domain 5 69 8.1E-29 T 29-03-2018 CXR48_RS00015 e0bd4960fbfcd779597c359ccdaf7698 71 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 5 63 1.3E-30 T 29-03-2018 IPR014330 RNA-binding S4-related,YaaA CXR48_RS00015 e0bd4960fbfcd779597c359ccdaf7698 71 Gene3D G3DSA:3.10.290.10 2 71 7.3E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CXR48_RS07585 ed18411aad77a21d4c25a20bb0238b8f 366 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 10 363 1.4E-132 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CXR48_RS07585 ed18411aad77a21d4c25a20bb0238b8f 366 Pfam PF01098 Cell cycle protein 11 365 2.2E-132 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CXR48_RS07585 ed18411aad77a21d4c25a20bb0238b8f 366 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 9 362 1.1E-186 T 29-03-2018 IPR013438 Sporulation stage V, protein E CXR48_RS07585 ed18411aad77a21d4c25a20bb0238b8f 366 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 322 346 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CXR48_RS15245 1c119b28e95928fbe8df7984a6f0db7d 233 SUPERFAMILY SSF53335 59 213 1.13E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS15245 1c119b28e95928fbe8df7984a6f0db7d 233 Pfam PF08241 Methyltransferase domain 79 184 2.4E-18 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CXR48_RS15245 1c119b28e95928fbe8df7984a6f0db7d 233 Gene3D G3DSA:3.40.50.150 52 209 2.8E-27 T 29-03-2018 CXR48_RS07510 581c52fb2beae37bfe25f0bf4aa48d04 415 Gene3D G3DSA:3.40.50.620 1 244 1.3E-53 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS07510 581c52fb2beae37bfe25f0bf4aa48d04 415 SUPERFAMILY SSF52374 1 106 9.98E-15 T 29-03-2018 CXR48_RS07510 581c52fb2beae37bfe25f0bf4aa48d04 415 SUPERFAMILY SSF52374 160 233 9.98E-15 T 29-03-2018 CXR48_RS07510 581c52fb2beae37bfe25f0bf4aa48d04 415 Hamap MF_01539 UPF0348 protein . 2 404 39.694 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 CXR48_RS07510 581c52fb2beae37bfe25f0bf4aa48d04 415 Pfam PF05636 HIGH Nucleotidyl Transferase 1 388 1.5E-132 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 CXR48_RS18305 5390ff88b865f6a65bb10c7ba0503146 298 Pfam PF01497 Periplasmic binding protein 37 274 1.5E-30 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CXR48_RS18305 5390ff88b865f6a65bb10c7ba0503146 298 Gene3D G3DSA:3.40.50.1980 134 298 1.1E-29 T 29-03-2018 CXR48_RS18305 5390ff88b865f6a65bb10c7ba0503146 298 Gene3D G3DSA:3.40.50.1980 28 133 4.1E-15 T 29-03-2018 CXR48_RS18305 5390ff88b865f6a65bb10c7ba0503146 298 SUPERFAMILY SSF53807 36 282 2.35E-46 T 29-03-2018 CXR48_RS17235 1df876b98a1f89992c66e7ff0988870c 484 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 11 446 1.7E-147 T 29-03-2018 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0005215|GO:0006810|GO:0016020 CXR48_RS17235 1df876b98a1f89992c66e7ff0988870c 484 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 16 452 2.6E-144 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CXR48_RS12980 74457e83030137e1c7c44d83f1be1be6 276 Pfam PF01578 Cytochrome C assembly protein 67 271 3.4E-38 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CXR48_RS05675 95bd4d23695a51d46d280bc195676f87 132 Gene3D G3DSA:1.10.490.10 4 129 2.2E-34 T 29-03-2018 CXR48_RS05675 95bd4d23695a51d46d280bc195676f87 132 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 52 76 - T 29-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CXR48_RS05675 95bd4d23695a51d46d280bc195676f87 132 SUPERFAMILY SSF46458 8 124 4.5E-39 T 29-03-2018 IPR009050 Globin-like CXR48_RS05675 95bd4d23695a51d46d280bc195676f87 132 Pfam PF01152 Bacterial-like globin 9 122 1.8E-31 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CXR48_RS17940 4f074b9cf009eb47676209e3ef4a89a2 256 SUPERFAMILY SSF53448 2 227 8.63E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS17940 4f074b9cf009eb47676209e3ef4a89a2 256 Gene3D G3DSA:3.90.550.10 2 256 1.3E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS17940 4f074b9cf009eb47676209e3ef4a89a2 256 Pfam PF00535 Glycosyl transferase family 2 5 168 1.8E-26 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 Gene3D G3DSA:3.50.50.60 93 249 2.4E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 Gene3D G3DSA:3.50.50.60 1 92 3.0E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 Gene3D G3DSA:3.50.50.60 264 355 2.2E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 318 7.8E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 SUPERFAMILY SSF51905 1 330 3.65E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 1.5E-6 T 29-03-2018 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.5E-6 T 29-03-2018 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 1.5E-6 T 29-03-2018 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.2E-10 T 29-03-2018 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.2E-10 T 29-03-2018 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.2E-10 T 29-03-2018 CXR48_RS06070 7096ade66e30a83287c7cac1d3dfbec2 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.2E-10 T 29-03-2018 CXR48_RS01635 c84e0af885279747c00fd978c103565e 209 Pfam PF01810 LysE type translocator 12 201 5.0E-49 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CXR48_RS04455 65aa9fd30f3e8cdc17222a032c535129 244 Pfam PF13171 Protein of unknown function (DUF4004) 38 228 6.8E-73 T 29-03-2018 IPR025063 Protein of unknown function DUF4004 CXR48_RS04455 65aa9fd30f3e8cdc17222a032c535129 244 Gene3D G3DSA:1.10.1660.10 35 112 1.6E-7 T 29-03-2018 CXR48_RS15415 2f844a73f18d93c32133ac9e62b9fb1f 145 Pfam PF14039 YusW-like protein 46 134 1.3E-20 T 29-03-2018 IPR025623 YusW-like protein CXR48_RS06065 e97a7951fd21a080ca15231d493fa80b 138 Pfam PF07849 Protein of unknown function (DUF1641) 101 121 1.0E-5 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 CXR48_RS01725 c13e548c4507f4d060667a49b2835e10 106 Pfam PF00355 Rieske [2Fe-2S] domain 8 93 5.6E-16 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CXR48_RS01725 c13e548c4507f4d060667a49b2835e10 106 Gene3D G3DSA:2.102.10.10 6 106 2.3E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CXR48_RS01725 c13e548c4507f4d060667a49b2835e10 106 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 7 105 9.0E-33 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CXR48_RS01725 c13e548c4507f4d060667a49b2835e10 106 SUPERFAMILY SSF50022 6 105 7.86E-32 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CXR48_RS07765 3a85f497645f1673352fd55815bae309 382 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 6.3E-147 T 29-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CXR48_RS07765 3a85f497645f1673352fd55815bae309 382 SUPERFAMILY SSF52374 159 371 3.75E-85 T 29-03-2018 CXR48_RS07765 3a85f497645f1673352fd55815bae309 382 Pfam PF14306 PUA-like domain 4 153 4.4E-49 T 29-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CXR48_RS07765 3a85f497645f1673352fd55815bae309 382 Gene3D G3DSA:3.40.50.620 173 380 2.8E-90 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS07765 3a85f497645f1673352fd55815bae309 382 SUPERFAMILY SSF88697 4 156 1.39E-47 T 29-03-2018 IPR015947 PUA-like domain CXR48_RS07765 3a85f497645f1673352fd55815bae309 382 Pfam PF01747 ATP-sulfurylase 161 371 1.8E-93 T 29-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CXR48_RS07765 3a85f497645f1673352fd55815bae309 382 Gene3D G3DSA:3.10.400.10 2 172 7.5E-56 T 29-03-2018 CXR48_RS07765 3a85f497645f1673352fd55815bae309 382 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 20 375 52.809 T 29-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CXR48_RS13810 bb6a55df19e09498a0fdabd749288177 137 Gene3D G3DSA:1.20.120.20 9 136 3.9E-8 T 29-03-2018 CXR48_RS13810 bb6a55df19e09498a0fdabd749288177 137 Pfam PF12732 YtxH-like protein 12 93 6.8E-21 T 29-03-2018 IPR024623 Uncharacterised protein family YtxH CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 SUPERFAMILY SSF51735 144 314 1.53E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 Gene3D G3DSA:3.90.180.10 3 159 2.1E-44 T 29-03-2018 CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 SMART SM00829 17 346 1.3E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 Pfam PF00107 Zinc-binding dehydrogenase 180 308 1.6E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 SUPERFAMILY SSF50129 5 179 1.19E-52 T 29-03-2018 IPR011032 GroES-like CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 6 348 53.918 T 29-03-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 8 347 7.3E-170 T 29-03-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 139 8.3E-34 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 Gene3D G3DSA:3.40.50.10730 160 317 5.5E-28 T 29-03-2018 CXR48_RS08475 fca87e2f117db1557a12cf28beb9aa87 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 67 81 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CXR48_RS06050 48f3bf36c84abf1656c3b438b6ecd381 245 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CXR48_RS06050 48f3bf36c84abf1656c3b438b6ecd381 245 Pfam PF00005 ABC transporter 27 168 8.9E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS06050 48f3bf36c84abf1656c3b438b6ecd381 245 Gene3D G3DSA:3.40.50.300 3 244 2.0E-58 T 29-03-2018 CXR48_RS06050 48f3bf36c84abf1656c3b438b6ecd381 245 SMART SM00382 36 217 5.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS06050 48f3bf36c84abf1656c3b438b6ecd381 245 SUPERFAMILY SSF52540 23 233 7.61E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS03965 c290cbab32d1e0e0eb4db5a7aca587d6 333 SUPERFAMILY SSF52518 9 328 1.0E-98 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CXR48_RS03965 c290cbab32d1e0e0eb4db5a7aca587d6 333 Gene3D G3DSA:3.40.50.970 4 331 9.4E-84 T 29-03-2018 CXR48_RS03965 c290cbab32d1e0e0eb4db5a7aca587d6 333 Pfam PF00676 Dehydrogenase E1 component 22 316 1.8E-91 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CXR48_RS08210 abc554ff02fe1957b9f5e3449d4f342a 166 Pfam PF03975 CheD chemotactic sensory transduction 52 158 4.6E-33 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CXR48_RS08210 abc554ff02fe1957b9f5e3449d4f342a 166 SUPERFAMILY SSF64438 8 163 1.28E-44 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CXR48_RS08210 abc554ff02fe1957b9f5e3449d4f342a 166 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 5 162 26.525 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CXR48_RS12365 13cff0375d82a4099d57dca43c306cc9 208 Pfam PF09335 SNARE associated Golgi protein 53 171 4.4E-24 T 29-03-2018 IPR032816 SNARE associated Golgi protein CXR48_RS02180 0857d77f5e9a167091bd132ee77ca30d 96 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 2.6E-27 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CXR48_RS02180 0857d77f5e9a167091bd132ee77ca30d 96 Pfam PF12823 Domain of unknown function (DUF3817) 7 92 2.4E-21 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CXR48_RS10680 c0784ee00b847b3d5b7c1304a8d998b5 185 Pfam PF07187 Protein of unknown function (DUF1405) 12 169 3.5E-60 T 29-03-2018 IPR009845 Protein of unknown function DUF1405 CXR48_RS18410 1540136433aecdf7139fa449491dfbb0 297 SUPERFAMILY SSF46689 198 269 3.63E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CXR48_RS18410 1540136433aecdf7139fa449491dfbb0 297 Pfam PF13556 PucR C-terminal helix-turn-helix domain 235 288 7.4E-14 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CXR48_RS18410 1540136433aecdf7139fa449491dfbb0 297 Gene3D G3DSA:1.10.10.60 222 272 1.3E-8 T 29-03-2018 CXR48_RS09740 ee4fd7924528b37886e3fe44526a6bcd 106 Pfam PF14191 YodL-like 27 98 2.0E-7 T 29-03-2018 IPR025923 YodL-like CXR48_RS09740 ee4fd7924528b37886e3fe44526a6bcd 106 ProDom PD030115 YODL GK1575 3 104 7.0E-44 T 29-03-2018 CXR48_RS12970 49e2aa73f1014859b59a69c1d88edba3 260 Gene3D G3DSA:3.40.50.10090 162 260 2.1E-16 T 29-03-2018 CXR48_RS12970 49e2aa73f1014859b59a69c1d88edba3 260 Pfam PF02602 Uroporphyrinogen-III synthase HemD 24 249 1.8E-48 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS12970 49e2aa73f1014859b59a69c1d88edba3 260 Gene3D G3DSA:3.40.50.10090 41 161 3.1E-27 T 29-03-2018 CXR48_RS12970 49e2aa73f1014859b59a69c1d88edba3 260 SUPERFAMILY SSF69618 9 255 1.44E-60 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CXR48_RS01665 a7b73cf7844fb3f6fab6df5955775e40 197 Gene3D G3DSA:3.40.50.300 1 182 1.8E-17 T 29-03-2018 CXR48_RS01665 a7b73cf7844fb3f6fab6df5955775e40 197 Pfam PF13238 AAA domain 3 127 3.9E-9 T 29-03-2018 CXR48_RS01665 a7b73cf7844fb3f6fab6df5955775e40 197 SUPERFAMILY SSF52540 1 165 2.42E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS01855 e0bce6b9eaaaf6589b70b18b4f8e0836 153 Gene3D G3DSA:2.30.110.10 1 153 3.9E-9 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CXR48_RS05310 44b4b6e9ba92018eb60cff649ec62fab 58 PIRSF PIRSF037666 1 58 5.4E-34 T 29-03-2018 IPR017257 Spore germination protein GerPD, predicted CXR48_RS04225 82a098a6bb92505cf3c51d37d6b3a71d 145 Pfam PF01475 Ferric uptake regulator family 16 133 2.5E-40 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CXR48_RS04225 82a098a6bb92505cf3c51d37d6b3a71d 145 Gene3D G3DSA:1.10.10.10 1 88 8.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04225 82a098a6bb92505cf3c51d37d6b3a71d 145 SUPERFAMILY SSF46785 8 137 3.2E-42 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS02940 ef1d314f4996f595f66e3439c94a9140 404 Gene3D G3DSA:1.20.1250.20 210 395 1.6E-19 T 29-03-2018 CXR48_RS02940 ef1d314f4996f595f66e3439c94a9140 404 Gene3D G3DSA:1.20.1250.20 4 205 1.1E-21 T 29-03-2018 CXR48_RS02940 ef1d314f4996f595f66e3439c94a9140 404 SUPERFAMILY SSF103473 13 393 3.27E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS02940 ef1d314f4996f595f66e3439c94a9140 404 Pfam PF07690 Major Facilitator Superfamily 38 358 1.9E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS07385 3fe5e956b22e4e4edcb7b0cd0aa3109a 158 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 3 157 2.0E-51 T 29-03-2018 IPR020229 Uncharacterised protein YlaL CXR48_RS18505 bcff1e4b8f10963fc71aeeb8a3c2eeae 121 Pfam PF14176 YxiJ-like protein 22 115 3.7E-24 T 29-03-2018 IPR025551 YxiJ-like protein CXR48_RS11810 0f6e7dccd676116002a2ee1fb06063ee 264 ProDom PD123329 YQHG BH2818 1 260 2.0E-127 T 29-03-2018 IPR024562 Uncharacterised protein family YqhG CXR48_RS11810 0f6e7dccd676116002a2ee1fb06063ee 264 Pfam PF11079 Bacterial protein YqhG of unknown function 1 258 4.0E-121 T 29-03-2018 IPR024562 Uncharacterised protein family YqhG CXR48_RS09005 a583caa5fbe5d7a13e0df01523b7fe36 472 PRINTS PR00175 Sodium/alanine symporter signature 207 226 1.8E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS09005 a583caa5fbe5d7a13e0df01523b7fe36 472 PRINTS PR00175 Sodium/alanine symporter signature 89 111 1.8E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS09005 a583caa5fbe5d7a13e0df01523b7fe36 472 PRINTS PR00175 Sodium/alanine symporter signature 179 197 1.8E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS09005 a583caa5fbe5d7a13e0df01523b7fe36 472 PRINTS PR00175 Sodium/alanine symporter signature 298 316 1.8E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS09005 a583caa5fbe5d7a13e0df01523b7fe36 472 PRINTS PR00175 Sodium/alanine symporter signature 341 363 1.8E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS09005 a583caa5fbe5d7a13e0df01523b7fe36 472 PRINTS PR00175 Sodium/alanine symporter signature 401 421 1.8E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS09005 a583caa5fbe5d7a13e0df01523b7fe36 472 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 89 104 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS09005 a583caa5fbe5d7a13e0df01523b7fe36 472 Pfam PF01235 Sodium:alanine symporter family 52 444 7.7E-159 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS09005 a583caa5fbe5d7a13e0df01523b7fe36 472 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 432 1.7E-164 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CXR48_RS08960 4968375434a67a2eb854a98afbf1b9f8 80 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 8 74 1.1E-29 T 29-03-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like CXR48_RS08960 4968375434a67a2eb854a98afbf1b9f8 80 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 80 33.241 T 29-03-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like CXR48_RS13830 d0f4d28340c39f8acd92af14ef94ebaa 201 Gene3D G3DSA:2.40.50.140 91 200 7.7E-40 T 29-03-2018 CXR48_RS13830 d0f4d28340c39f8acd92af14ef94ebaa 201 SUPERFAMILY SSF50249 92 199 1.32E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS13830 d0f4d28340c39f8acd92af14ef94ebaa 201 Pfam PF01588 Putative tRNA binding domain 96 197 3.0E-26 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CXR48_RS13830 d0f4d28340c39f8acd92af14ef94ebaa 201 Gene3D G3DSA:3.30.1940.10 23 90 5.2E-25 T 29-03-2018 IPR027855 Domain of unknown function DUF4479 CXR48_RS13830 d0f4d28340c39f8acd92af14ef94ebaa 201 Pfam PF14794 Domain of unknown function (DUF4479) 23 91 8.5E-27 T 29-03-2018 IPR027855 Domain of unknown function DUF4479 CXR48_RS17885 0226c5a4bb755870f7b7efcddfbe7c16 153 ProDom PD034110 YWEA MEMBRANE YUAB TRANSMEMBRANE ORF-1 1 153 5.0E-66 T 29-03-2018 IPR034650 YuaB-like CXR48_RS07370 579d4c5ee02ad54205906a54f9850a93 69 Gene3D G3DSA:3.90.1670.10 1 55 2.4E-4 T 29-03-2018 IPR024064 FdhE-like CXR48_RS07370 579d4c5ee02ad54205906a54f9850a93 69 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 2.0E-31 T 29-03-2018 IPR019241 Protein of unknown function DUF2197 CXR48_RS02170 db3253c8c88480ed58f0345aff7e70f0 140 SUPERFAMILY SSF50475 4 132 4.12E-31 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CXR48_RS02170 db3253c8c88480ed58f0345aff7e70f0 140 Gene3D G3DSA:2.30.110.10 2 138 7.7E-25 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CXR48_RS02170 db3253c8c88480ed58f0345aff7e70f0 140 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 7 125 1.3E-18 T 29-03-2018 CXR48_RS17040 c68192aa69772343cbc627069021784d 196 Pfam PF02417 Chromate transporter 6 172 1.2E-34 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CXR48_RS02210 36e43670e6d16258b446aab366035821 420 Gene3D G3DSA:3.90.550.10 35 311 2.6E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS02210 36e43670e6d16258b446aab366035821 420 SUPERFAMILY SSF53448 36 320 6.06E-63 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS02210 36e43670e6d16258b446aab366035821 420 Pfam PF13641 Glycosyltransferase like family 2 49 279 2.9E-31 T 29-03-2018 CXR48_RS14215 5bce5fbb6cf75180b917bb3f5366a16d 443 PIRSF PIRSF006446 1 443 5.6E-115 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CXR48_RS14215 5bce5fbb6cf75180b917bb3f5366a16d 443 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 433 2.4E-121 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CXR48_RS11925 b63f10c7c18113f58344fe1231a6eae7 104 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 101 3.3E-38 T 29-03-2018 IPR002767 Thiamine-binding protein CXR48_RS11925 b63f10c7c18113f58344fe1231a6eae7 104 Gene3D G3DSA:3.30.70.930 1 104 4.4E-36 T 29-03-2018 IPR029756 MTH1187/YkoF-like CXR48_RS11925 b63f10c7c18113f58344fe1231a6eae7 104 Pfam PF01910 Thiamine-binding protein 4 98 4.0E-34 T 29-03-2018 IPR002767 Thiamine-binding protein CXR48_RS11925 b63f10c7c18113f58344fe1231a6eae7 104 SUPERFAMILY SSF89957 1 103 2.35E-32 T 29-03-2018 IPR029756 MTH1187/YkoF-like CXR48_RS03145 a06224c7c41baab26645b53cef7e3cbd 341 Pfam PF08271 TFIIB zinc-binding 5 37 3.8E-7 T 29-03-2018 IPR013137 Zinc finger, TFIIB-type CXR48_RS03145 a06224c7c41baab26645b53cef7e3cbd 341 Gene3D G3DSA:2.20.25.10 50 112 1.7E-6 T 29-03-2018 CXR48_RS03145 a06224c7c41baab26645b53cef7e3cbd 341 Gene3D G3DSA:3.90.820.10 1 49 3.5E-13 T 29-03-2018 CXR48_RS15960 36a254e727cfebad0c0413239a3833df 411 Gene3D G3DSA:1.20.1250.20 211 409 6.8E-6 T 29-03-2018 CXR48_RS15960 36a254e727cfebad0c0413239a3833df 411 SUPERFAMILY SSF103473 15 397 6.02E-30 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS15960 36a254e727cfebad0c0413239a3833df 411 Gene3D G3DSA:1.20.1250.20 9 210 1.1E-15 T 29-03-2018 CXR48_RS15960 36a254e727cfebad0c0413239a3833df 411 Pfam PF07690 Major Facilitator Superfamily 20 356 5.6E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS15960 36a254e727cfebad0c0413239a3833df 411 PRINTS PR01988 Putative bacilysin exporter bacE signature 147 168 3.3E-8 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS15960 36a254e727cfebad0c0413239a3833df 411 PRINTS PR01988 Putative bacilysin exporter bacE signature 301 324 3.3E-8 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS15960 36a254e727cfebad0c0413239a3833df 411 PRINTS PR01988 Putative bacilysin exporter bacE signature 174 191 3.3E-8 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS15960 36a254e727cfebad0c0413239a3833df 411 PRINTS PR01988 Putative bacilysin exporter bacE signature 55 73 3.3E-8 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 405 429 - T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 SUPERFAMILY SSF56235 42 584 1.79E-175 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 49 577 6.3E-213 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 Pfam PF01019 Gamma-glutamyltranspeptidase 64 579 2.9E-173 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 423 4.5E-78 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 71 96 4.5E-78 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 460 475 4.5E-78 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 429 447 4.5E-78 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 146 164 4.5E-78 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 484 501 4.5E-78 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 164 183 4.5E-78 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 291 310 4.5E-78 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS09295 44591e0772b00791250cd935b9c9c6f1 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 261 277 4.5E-78 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CXR48_RS10380 d2794322f0c9e15167b48cafb0465c40 67 Pfam PF17356 Phage-like element PBSX protein XtrA 3 66 4.1E-23 T 29-03-2018 IPR035530 Phage-like element PBSX protein XtrA CXR48_RS10380 d2794322f0c9e15167b48cafb0465c40 67 ProDom PD027572 XTRA PBSX RELATED YQAO ELEMENT PHAGE PHAGE-LIKE 13 61 6.0E-17 T 29-03-2018 IPR035530 Phage-like element PBSX protein XtrA CXR48_RS03290 2388b238ff0d0ae2681ac6e95fb7a94f 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 204 5.1E-42 T 29-03-2018 CXR48_RS03290 2388b238ff0d0ae2681ac6e95fb7a94f 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 2.3E-91 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS03290 2388b238ff0d0ae2681ac6e95fb7a94f 227 Gene3D G3DSA:3.40.50.880 1 221 2.0E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS03290 2388b238ff0d0ae2681ac6e95fb7a94f 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 217 43.477 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS03290 2388b238ff0d0ae2681ac6e95fb7a94f 227 PIRSF PIRSF001586 1 222 1.9E-85 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CXR48_RS03290 2388b238ff0d0ae2681ac6e95fb7a94f 227 SUPERFAMILY SSF52317 2 219 3.2E-75 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CXR48_RS03290 2388b238ff0d0ae2681ac6e95fb7a94f 227 SMART SM01211 1 219 2.7E-132 T 29-03-2018 CXR48_RS17460 6dbe3ebc80d1ef4df08cf932f99078d4 151 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 139 3.9E-37 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CXR48_RS17460 6dbe3ebc80d1ef4df08cf932f99078d4 151 Gene3D G3DSA:3.40.50.2300 1 150 3.4E-44 T 29-03-2018 CXR48_RS17460 6dbe3ebc80d1ef4df08cf932f99078d4 151 SUPERFAMILY SSF52788 1 145 2.75E-37 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CXR48_RS17460 6dbe3ebc80d1ef4df08cf932f99078d4 151 SMART SM00226 1 144 8.7E-43 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CXR48_RS17460 6dbe3ebc80d1ef4df08cf932f99078d4 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 3.4E-9 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CXR48_RS17460 6dbe3ebc80d1ef4df08cf932f99078d4 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 76 91 3.4E-9 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CXR48_RS17460 6dbe3ebc80d1ef4df08cf932f99078d4 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 116 131 3.4E-9 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CXR48_RS16530 e5e66a1ad6760c53363626f620c81000 108 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 7 106 1.0E-34 T 29-03-2018 CXR48_RS03530 f64354e4df1ab25b38fb6c53794f867c 288 Gene3D G3DSA:3.30.750.24 17 278 6.9E-13 T 29-03-2018 IPR002645 STAS domain CXR48_RS03530 f64354e4df1ab25b38fb6c53794f867c 288 Pfam PF01740 STAS domain 174 270 4.4E-11 T 29-03-2018 IPR002645 STAS domain CXR48_RS03530 f64354e4df1ab25b38fb6c53794f867c 288 SUPERFAMILY SSF52091 169 276 7.26E-16 T 29-03-2018 IPR002645 STAS domain CXR48_RS15995 c42e6037608a0bcae42c6da89494d822 376 Gene3D G3DSA:3.90.1150.10 235 375 3.4E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS15995 c42e6037608a0bcae42c6da89494d822 376 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 2 364 9.0E-129 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CXR48_RS15995 c42e6037608a0bcae42c6da89494d822 376 Gene3D G3DSA:3.40.640.10 2 234 1.8E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS15995 c42e6037608a0bcae42c6da89494d822 376 PIRSF PIRSF000390 1 371 7.5E-114 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CXR48_RS15995 c42e6037608a0bcae42c6da89494d822 376 SUPERFAMILY SSF53383 2 368 1.02E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS09530 e58d6c89a2d5d0c3adfe3772703330ff 114 SUPERFAMILY SSF50729 11 113 2.06E-27 T 29-03-2018 IPR011993 PH domain-like CXR48_RS09530 e58d6c89a2d5d0c3adfe3772703330ff 114 Gene3D G3DSA:2.30.29.50 6 93 9.5E-24 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CXR48_RS09530 e58d6c89a2d5d0c3adfe3772703330ff 114 Pfam PF08000 Bacterial PH domain 11 111 7.5E-24 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CXR48_RS15850 4b657d29e000ce3bf14283fea62aa1a2 136 Gene3D G3DSA:1.10.260.40 1 135 2.1E-22 T 29-03-2018 CXR48_RS15850 4b657d29e000ce3bf14283fea62aa1a2 136 Pfam PF13560 Helix-turn-helix domain 4 62 1.2E-15 T 29-03-2018 CXR48_RS15850 4b657d29e000ce3bf14283fea62aa1a2 136 SMART SM00530 7 63 8.1E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CXR48_RS15850 4b657d29e000ce3bf14283fea62aa1a2 136 SUPERFAMILY SSF47413 3 65 1.0E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CXR48_RS12590 ba655679ee481c69713bc1aacb21cad2 217 Pfam PF01596 O-methyltransferase 35 215 3.9E-31 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CXR48_RS12590 ba655679ee481c69713bc1aacb21cad2 217 SUPERFAMILY SSF53335 9 216 9.51E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS12590 ba655679ee481c69713bc1aacb21cad2 217 Gene3D G3DSA:3.40.50.150 5 217 1.4E-40 T 29-03-2018 CXR48_RS11705 027a266ff91a3b39ddae0f5be829f134 230 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 29 225 3.9E-71 T 29-03-2018 IPR014195 Sporulation stage III, protein AG CXR48_RS10425 f3db186e101a3c9e64d3e25a1b610dc7 85 Pfam PF17448 Uncharacterized protein YqaH 1 83 4.4E-35 T 29-03-2018 IPR020278 Uncharacterized protein YqaH CXR48_RS10425 f3db186e101a3c9e64d3e25a1b610dc7 85 ProDom PD061343 YQAH DNA SEQUENCE 1 82 3.0E-34 T 29-03-2018 IPR020278 Uncharacterized protein YqaH CXR48_RS10295 f045d686f459db93ea6333c9d8a4ab5a 138 Gene3D G3DSA:2.160.20.50 32 85 4.6E-4 T 29-03-2018 CXR48_RS10295 f045d686f459db93ea6333c9d8a4ab5a 138 Pfam PF01391 Collagen triple helix repeat (20 copies) 45 79 1.4E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CXR48_RS11720 31c00c9006f970ee261d61e4838f3d6b 129 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 27 127 2.4E-40 T 29-03-2018 IPR014211 Stage III sporulation protein AD CXR48_RS11720 31c00c9006f970ee261d61e4838f3d6b 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 71 125 7.2E-20 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CXR48_RS11720 31c00c9006f970ee261d61e4838f3d6b 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 3 57 9.0E-13 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CXR48_RS15360 e12841b5433b8fd5d3b0c7dd26ceb3d6 302 Gene3D G3DSA:3.20.20.220 9 300 8.6E-70 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CXR48_RS15360 e12841b5433b8fd5d3b0c7dd26ceb3d6 302 SUPERFAMILY SSF51730 34 297 9.81E-73 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CXR48_RS15360 e12841b5433b8fd5d3b0c7dd26ceb3d6 302 Pfam PF01619 Proline dehydrogenase 41 295 6.0E-38 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CXR48_RS15360 e12841b5433b8fd5d3b0c7dd26ceb3d6 302 PIRSF PIRSF000196 1 302 4.9E-122 T 29-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CXR48_RS09820 46cc65df61c34f7e0ee2cddeaf8fa081 259 Pfam PF00583 Acetyltransferase (GNAT) family 158 244 1.1E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS09820 46cc65df61c34f7e0ee2cddeaf8fa081 259 Gene3D G3DSA:3.40.630.30 99 254 1.6E-17 T 29-03-2018 CXR48_RS09820 46cc65df61c34f7e0ee2cddeaf8fa081 259 SUPERFAMILY SSF55729 148 254 6.71E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS15645 adbb82bd3a2bdf5459d675d8eddc625d 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 222 2.3E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15645 adbb82bd3a2bdf5459d675d8eddc625d 227 SUPERFAMILY SSF161098 9 223 1.57E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15645 adbb82bd3a2bdf5459d675d8eddc625d 227 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 19 223 4.3E-69 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CXR48_RS15645 adbb82bd3a2bdf5459d675d8eddc625d 227 Gene3D G3DSA:1.10.3720.10 3 224 9.2E-36 T 29-03-2018 CXR48_RS18160 076421054402bc48533542b810b80dcb 128 Pfam PF03788 LrgA family 22 110 6.6E-28 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CXR48_RS18160 076421054402bc48533542b810b80dcb 128 Hamap MF_01143 Holin-like protein CidA [cidA]. 1 119 24.33 T 29-03-2018 IPR023760 Holin-like protein CidA GO:0016021 CXR48_RS05450 44f1718458fe988d00a23dededb963dd 65 Pfam PF12758 Protein of unknown function (DUF3813) 1 64 5.4E-28 T 29-03-2018 IPR024217 Protein of unknown function DUF3813 CXR48_RS13975 287e6b3408116522d5dcf8e743d3d728 273 Gene3D G3DSA:1.10.3720.10 1 260 3.6E-42 T 29-03-2018 CXR48_RS13975 287e6b3408116522d5dcf8e743d3d728 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 265 1.8E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS13975 287e6b3408116522d5dcf8e743d3d728 273 SUPERFAMILY SSF161098 5 273 2.99E-68 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS10105 fd735df1e3a8920eb108dce665e58ef2 60 Pfam PF10782 Zinc-finger 2 58 7.1E-29 T 29-03-2018 IPR019718 Protein of unknown function DUF2602 CXR48_RS03640 263ed27ff43d8040caf5fbf01efab68c 394 SUPERFAMILY SSF103473 14 390 5.1E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS03640 263ed27ff43d8040caf5fbf01efab68c 394 Pfam PF07690 Major Facilitator Superfamily 241 382 3.1E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS03640 263ed27ff43d8040caf5fbf01efab68c 394 Pfam PF07690 Major Facilitator Superfamily 22 238 1.1E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS03640 263ed27ff43d8040caf5fbf01efab68c 394 Gene3D G3DSA:1.20.1250.20 10 201 3.9E-22 T 29-03-2018 CXR48_RS03640 263ed27ff43d8040caf5fbf01efab68c 394 Gene3D G3DSA:1.20.1250.20 203 392 1.1E-19 T 29-03-2018 CXR48_RS03640 263ed27ff43d8040caf5fbf01efab68c 394 PRINTS PR01035 Tetracycline resistance protein signature 141 163 2.3E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS03640 263ed27ff43d8040caf5fbf01efab68c 394 PRINTS PR01035 Tetracycline resistance protein signature 169 189 2.3E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS03640 263ed27ff43d8040caf5fbf01efab68c 394 PRINTS PR01035 Tetracycline resistance protein signature 27 43 2.3E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CXR48_RS00395 906ad929979e7f37a5d1629076136af5 829 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 44 806 3.8E-304 T 29-03-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS00395 906ad929979e7f37a5d1629076136af5 829 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 622 806 4.2E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS00395 906ad929979e7f37a5d1629076136af5 829 SMART SM00331 594 806 1.0E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS00395 906ad929979e7f37a5d1629076136af5 829 SUPERFAMILY SSF81606 595 807 9.81E-22 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS00395 906ad929979e7f37a5d1629076136af5 829 Gene3D G3DSA:3.60.40.10 586 817 3.8E-25 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS00395 906ad929979e7f37a5d1629076136af5 829 SMART SM00332 322 804 3.3E-12 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CXR48_RS17775 011f0c54727b42840a6cb0621206024a 257 Gene3D G3DSA:1.20.5.170 67 195 2.4E-5 T 29-03-2018 CXR48_RS17775 011f0c54727b42840a6cb0621206024a 257 Gene3D G3DSA:1.10.10.60 4 66 4.2E-5 T 29-03-2018 CXR48_RS17775 011f0c54727b42840a6cb0621206024a 257 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 3 79 7.0E-44 T 29-03-2018 IPR014243 Transcription factor, RsfA CXR48_RS17775 011f0c54727b42840a6cb0621206024a 257 Gene3D G3DSA:1.20.5.370 196 227 0.034 T 29-03-2018 CXR48_RS07515 d00de6056eff88c404523e1ad1bdcc59 172 Pfam PF02620 Uncharacterized ACR, COG1399 56 165 1.3E-24 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CXR48_RS15110 8fe811449f85551c55e1398df3fd79ab 325 Gene3D G3DSA:2.70.70.10 172 325 2.4E-25 T 29-03-2018 CXR48_RS15110 8fe811449f85551c55e1398df3fd79ab 325 Pfam PF01551 Peptidase family M23 202 300 5.5E-21 T 29-03-2018 IPR016047 Peptidase M23 CXR48_RS15110 8fe811449f85551c55e1398df3fd79ab 325 Gene3D G3DSA:1.10.530.10 17 162 2.4E-6 T 29-03-2018 CXR48_RS15110 8fe811449f85551c55e1398df3fd79ab 325 SUPERFAMILY SSF51261 118 313 5.75E-35 T 29-03-2018 IPR011055 Duplicated hybrid motif CXR48_RS02620 f3f63a825384a2c1f797aa239e167a42 258 Pfam PF01925 Sulfite exporter TauE/SafE 9 252 1.0E-43 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CXR48_RS18450 002b9550d0687c208caf4fa6054d719d 397 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 395 8.1E-50 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CXR48_RS18450 002b9550d0687c208caf4fa6054d719d 397 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 395 1.5E-133 T 29-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 CXR48_RS18450 002b9550d0687c208caf4fa6054d719d 397 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 7.8E-16 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CXR48_RS04200 e907d7d0cf918d7668af5e596dc03cc9 176 SUPERFAMILY SSF159234 3 171 2.22E-32 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CXR48_RS04200 e907d7d0cf918d7668af5e596dc03cc9 176 PIRSF PIRSF028345 1 176 2.0E-79 T 29-03-2018 IPR016882 Uncharacterised protein family UPF0374 CXR48_RS04200 e907d7d0cf918d7668af5e596dc03cc9 176 Gene3D G3DSA:2.40.380.10 14 171 3.3E-32 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CXR48_RS04200 e907d7d0cf918d7668af5e596dc03cc9 176 Hamap MF_01568 UPF0374 protein . 1 175 49.453 T 29-03-2018 IPR016882 Uncharacterised protein family UPF0374 CXR48_RS04200 e907d7d0cf918d7668af5e596dc03cc9 176 Pfam PF04167 Protein of unknown function (DUF402) 60 124 5.5E-17 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CXR48_RS16395 0e7cd370c8231016738d50ddc974c1d8 470 Gene3D G3DSA:3.90.20.10 10 137 7.7E-5 T 29-03-2018 CXR48_RS16395 0e7cd370c8231016738d50ddc974c1d8 470 Gene3D G3DSA:3.90.1720.10 333 469 1.5E-30 T 29-03-2018 CXR48_RS16395 0e7cd370c8231016738d50ddc974c1d8 470 Gene3D G3DSA:1.20.120.330 150 285 0.21 T 29-03-2018 CXR48_RS16395 0e7cd370c8231016738d50ddc974c1d8 470 SUPERFAMILY SSF54001 336 467 1.32E-29 T 29-03-2018 CXR48_RS16395 0e7cd370c8231016738d50ddc974c1d8 470 Pfam PF00877 NlpC/P60 family 354 464 1.1E-29 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CXR48_RS16270 cd10bdd8c83dee0380fe756eec69fe89 85 Pfam PF07252 Protein of unknown function (DUF1433) 18 70 1.2E-9 T 29-03-2018 IPR009881 Protein of unknown function DUF1433 CXR48_RS16270 cd10bdd8c83dee0380fe756eec69fe89 85 Gene3D G3DSA:3.10.450.130 14 84 1.2E-12 T 29-03-2018 CXR48_RS18440 fd6443a2a8a17a69f11e13a056586655 378 Gene3D G3DSA:3.20.20.210 14 378 2.3E-98 T 29-03-2018 CXR48_RS18440 fd6443a2a8a17a69f11e13a056586655 378 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 25 373 3.7E-18 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CXR48_RS18440 fd6443a2a8a17a69f11e13a056586655 378 SUPERFAMILY SSF51726 22 378 4.32E-83 T 29-03-2018 CXR48_RS15945 4308420f5f855ffe99f24ad13acd0bc8 236 ProDom PD113106 YVBI TRANSMEMBRANE MEMBRANE YEBC YBEC 1 232 2.0E-46 T 29-03-2018 CXR48_RS07640 28611e55d8d12cd3bbfe13a8f63762a0 426 Pfam PF01546 Peptidase family M20/M25/M40 84 415 4.0E-31 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS07640 28611e55d8d12cd3bbfe13a8f63762a0 426 SUPERFAMILY SSF55031 213 305 1.64E-8 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS07640 28611e55d8d12cd3bbfe13a8f63762a0 426 Pfam PF07687 Peptidase dimerisation domain 186 306 2.0E-24 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS07640 28611e55d8d12cd3bbfe13a8f63762a0 426 SUPERFAMILY SSF53187 335 419 1.6E-61 T 29-03-2018 CXR48_RS07640 28611e55d8d12cd3bbfe13a8f63762a0 426 SUPERFAMILY SSF53187 7 195 1.6E-61 T 29-03-2018 CXR48_RS07640 28611e55d8d12cd3bbfe13a8f63762a0 426 Gene3D G3DSA:3.30.70.360 193 323 1.9E-17 T 29-03-2018 CXR48_RS07640 28611e55d8d12cd3bbfe13a8f63762a0 426 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 19 409 4.5E-126 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CXR48_RS07640 28611e55d8d12cd3bbfe13a8f63762a0 426 Gene3D G3DSA:3.40.630.10 7 192 7.7E-34 T 29-03-2018 CXR48_RS13950 ed8a5a3eb5f4f08f4b8cd370ad1b7d2c 511 ProSitePatterns PS01303 BCCT family of transporters signature. 311 320 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CXR48_RS13950 ed8a5a3eb5f4f08f4b8cd370ad1b7d2c 511 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 46 489 2.0E-183 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CXR48_RS13950 ed8a5a3eb5f4f08f4b8cd370ad1b7d2c 511 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 8 489 1.1E-198 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CXR48_RS18885 e3c1063695009bd112ee79487eeb9430 478 Gene3D G3DSA:3.30.70.270 114 291 4.2E-14 T 29-03-2018 CXR48_RS18885 e3c1063695009bd112ee79487eeb9430 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 133 283 1.0E-8 T 29-03-2018 IPR000477 Reverse transcriptase domain CXR48_RS04355 926cfdd630649b15a9273740f0ad1bfb 59 Pfam PF13040 Fur-regulated basic protein B 17 56 5.1E-13 T 29-03-2018 IPR025004 Transcriptional regulatory protein SenN/SenS CXR48_RS03600 f2f5e2f73544b743f5e90ab8ecae11b8 409 SUPERFAMILY SSF103473 14 400 2.49E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS03600 f2f5e2f73544b743f5e90ab8ecae11b8 409 Gene3D G3DSA:1.20.1250.20 19 210 1.0E-19 T 29-03-2018 CXR48_RS03600 f2f5e2f73544b743f5e90ab8ecae11b8 409 Gene3D G3DSA:1.20.1250.20 211 403 5.9E-22 T 29-03-2018 CXR48_RS03600 f2f5e2f73544b743f5e90ab8ecae11b8 409 Pfam PF07690 Major Facilitator Superfamily 24 355 2.3E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS06680 780d6eba22033667bf4ffed89d25962a 297 Gene3D G3DSA:3.30.2010.10 79 172 2.0E-19 T 29-03-2018 CXR48_RS06680 780d6eba22033667bf4ffed89d25962a 297 Pfam PF01435 Peptidase family M48 88 296 1.5E-38 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CXR48_RS06680 780d6eba22033667bf4ffed89d25962a 297 Hamap MF_00188 Protease HtpX [htpX]. 2 297 24.01 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CXR48_RS12430 d38cc6fbd71d75c5713c34660770c664 94 Pfam PF10852 Protein of unknown function (DUF2651) 17 86 9.4E-12 T 29-03-2018 IPR020258 Uncharacterised protein family YbeF CXR48_RS06235 33ed05a0223b223450cc872f1f2f012a 432 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 20 417 1.9E-91 T 29-03-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 CXR48_RS06235 33ed05a0223b223450cc872f1f2f012a 432 Pfam PF04466 Phage terminase large subunit 19 231 3.7E-80 T 29-03-2018 IPR035412 Phage terminase large subunit, N-terminal CXR48_RS06235 33ed05a0223b223450cc872f1f2f012a 432 Pfam PF17288 Terminase RNAseH like domain 268 410 3.2E-42 T 29-03-2018 IPR035413 Phage terminase large subunit, C-terminal CXR48_RS17485 69391be821bf774b00ea47d4a2852773 124 Pfam PF17094 Uncharacterised protein family (UPF0715) 3 115 1.2E-36 T 29-03-2018 IPR031374 Uncharacterised protein family UPF0715 CXR48_RS17485 69391be821bf774b00ea47d4a2852773 124 ProDom PD015812 YOPD YWLA YOAG 3 116 7.0E-38 T 29-03-2018 IPR031374 Uncharacterised protein family UPF0715 CXR48_RS06845 0e7933385803e62499e18cdb8ff78958 164 Pfam PF00578 AhpC/TSA family 37 147 1.3E-22 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CXR48_RS06845 0e7933385803e62499e18cdb8ff78958 164 Gene3D G3DSA:3.40.30.10 19 163 1.0E-28 T 29-03-2018 CXR48_RS06845 0e7933385803e62499e18cdb8ff78958 164 ProSitePatterns PS00194 Thioredoxin family active site. 56 74 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CXR48_RS06845 0e7933385803e62499e18cdb8ff78958 164 SUPERFAMILY SSF52833 2 161 6.18E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS00735 c57b126ac4154369d53b6398ff984cf8 209 SUPERFAMILY SSF50447 1 207 5.3E-81 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CXR48_RS00735 c57b126ac4154369d53b6398ff984cf8 209 Gene3D G3DSA:4.10.960.10 58 164 3.1E-33 T 29-03-2018 CXR48_RS00735 c57b126ac4154369d53b6398ff984cf8 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.298 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00735 c57b126ac4154369d53b6398ff984cf8 209 Pfam PF00297 Ribosomal protein L3 99 181 1.4E-16 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CXR48_RS00735 c57b126ac4154369d53b6398ff984cf8 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 1.5E-86 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CXR48_RS00735 c57b126ac4154369d53b6398ff984cf8 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site CXR48_RS06020 662d9d446809a7e52feefe7ddc469cc6 180 Pfam PF07849 Protein of unknown function (DUF1641) 118 154 5.9E-13 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 CXR48_RS04445 5bb8a83ac490637d2d2acb973f2ecfcf 303 Gene3D G3DSA:3.90.1720.10 134 302 1.5E-16 T 29-03-2018 CXR48_RS04445 5bb8a83ac490637d2d2acb973f2ecfcf 303 Pfam PF12671 Putative amidase domain 140 292 3.0E-39 T 29-03-2018 IPR024301 Putative amidase domain CXR48_RS12775 7963b3420b87ae10c83d608ec20974ac 381 Gene3D G3DSA:3.20.20.105 1 376 1.3E-163 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CXR48_RS12775 7963b3420b87ae10c83d608ec20974ac 381 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 8 375 6.1E-180 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CXR48_RS12775 7963b3420b87ae10c83d608ec20974ac 381 Pfam PF01702 Queuine tRNA-ribosyltransferase 134 367 6.4E-95 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CXR48_RS12775 7963b3420b87ae10c83d608ec20974ac 381 SUPERFAMILY SSF51713 7 371 7.32E-164 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CXR48_RS12775 7963b3420b87ae10c83d608ec20974ac 381 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 8 375 1.9E-190 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CXR48_RS12775 7963b3420b87ae10c83d608ec20974ac 381 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 6 370 57.946 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CXR48_RS08065 4974e9e4589e9ee18d21c921ca46ebf7 129 Pfam PF00460 Flagella basal body rod protein 8 38 1.5E-9 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CXR48_RS08065 4974e9e4589e9ee18d21c921ca46ebf7 129 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CXR48_RS08065 4974e9e4589e9ee18d21c921ca46ebf7 129 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 4 125 2.4E-39 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CXR48_RS08065 4974e9e4589e9ee18d21c921ca46ebf7 129 PIRSF PIRSF002889 2 128 3.3E-33 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CXR48_RS12075 247e76c51cb68f339dc0c1c12427d5c7 231 Pfam PF14181 YqfQ-like protein 42 231 3.7E-40 T 29-03-2018 IPR025571 YqfQ-like protein CXR48_RS12075 247e76c51cb68f339dc0c1c12427d5c7 231 Gene3D G3DSA:2.130.10.10 11 224 9.3E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CXR48_RS18610 8262924c3b51193bacff5819aca55bdf 393 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 391 4.5E-137 T 29-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 CXR48_RS18610 8262924c3b51193bacff5819aca55bdf 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.8E-21 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CXR48_RS18610 8262924c3b51193bacff5819aca55bdf 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 1.5E-60 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CXR48_RS12390 7f7d6158777be43eed6d9d980e18f07a 175 SUPERFAMILY SSF46785 3 174 4.67E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS12390 7f7d6158777be43eed6d9d980e18f07a 175 Pfam PF03551 Transcriptional regulator PadR-like family 6 82 2.9E-10 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CXR48_RS12390 7f7d6158777be43eed6d9d980e18f07a 175 Gene3D G3DSA:1.10.10.10 1 93 4.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS15355 3d1b577bc3e8795a22505969db61a5da 46 Pfam PF14115 YuzL-like protein 5 42 2.1E-15 T 29-03-2018 IPR025625 YuzL-like protein CXR48_RS14875 9ee8227561a8e3e516f2bea29f0db215 71 SMART SM00923 3 53 1.8E-27 T 29-03-2018 IPR005153 MbtH-like protein CXR48_RS14875 9ee8227561a8e3e516f2bea29f0db215 71 Pfam PF03621 MbtH-like protein 1 52 5.9E-25 T 29-03-2018 IPR005153 MbtH-like protein CXR48_RS14875 9ee8227561a8e3e516f2bea29f0db215 71 SUPERFAMILY SSF160582 1 66 2.48E-28 T 29-03-2018 CXR48_RS14875 9ee8227561a8e3e516f2bea29f0db215 71 Gene3D G3DSA:3.90.820.10 2 68 6.4E-31 T 29-03-2018 CXR48_RS09680 7dab47a3c042354bc9842f836cf1bc8a 307 Gene3D G3DSA:3.10.180.10 145 307 4.6E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS09680 7dab47a3c042354bc9842f836cf1bc8a 307 SUPERFAMILY SSF54593 2 278 1.27E-43 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS09680 7dab47a3c042354bc9842f836cf1bc8a 307 Gene3D G3DSA:3.10.180.10 1 144 1.1E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CXR48_RS09680 7dab47a3c042354bc9842f836cf1bc8a 307 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 263 1.5E-30 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CXR48_RS04575 8c23d125a376e56db9aff506f947b2ed 221 Pfam PF07875 Coat F domain 122 183 1.1E-15 T 29-03-2018 IPR012851 Spore coat protein CotF-like CXR48_RS04575 8c23d125a376e56db9aff506f947b2ed 221 Gene3D G3DSA:1.20.1260.10 17 179 7.9E-16 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS18385 4687903a3b40fb7569dc5f02d8faec25 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 2 226 6.2E-100 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CXR48_RS18385 4687903a3b40fb7569dc5f02d8faec25 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 227 337 1.0E-38 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CXR48_RS18385 4687903a3b40fb7569dc5f02d8faec25 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 326 4.1E-100 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CXR48_RS18385 4687903a3b40fb7569dc5f02d8faec25 338 PIRSF PIRSF000267 1 338 1.0E-110 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Pfam PF01391 Collagen triple helix repeat (20 copies) 2040 2088 1.1E-6 T 29-03-2018 IPR008160 Collagen triple helix repeat CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Pfam PF01391 Collagen triple helix repeat (20 copies) 192 249 2.1E-6 T 29-03-2018 IPR008160 Collagen triple helix repeat CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Pfam PF01391 Collagen triple helix repeat (20 copies) 2082 2139 4.4E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Pfam PF01391 Collagen triple helix repeat (20 copies) 150 208 9.7E-9 T 29-03-2018 IPR008160 Collagen triple helix repeat CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Pfam PF01391 Collagen triple helix repeat (20 copies) 1009 1065 5.1E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 441 494 1.1E-17 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1721 1776 1.0E-15 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1887 1940 4.1E-17 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1375 1431 2.0E-12 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 2047 2105 2.0E-18 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1833 1886 4.5E-19 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 616 675 6.6E-13 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 495 557 3.4E-14 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 558 615 1.5E-15 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1091 1167 1.8E-11 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 142 207 2.2E-15 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 381 440 7.9E-11 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1626 1674 1.6E-13 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1432 1492 9.3E-10 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 774 836 3.7E-13 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1994 2046 2.2E-18 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 676 721 1.2E-11 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 722 773 2.6E-17 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1941 1993 3.8E-18 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 208 277 1.7E-13 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1553 1625 1.6E-9 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1675 1720 2.0E-17 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1777 1832 2.7E-15 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 981 1071 1.2E-9 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1493 1552 7.5E-12 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1168 1253 5.6E-8 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 885 958 3.5E-12 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 317 380 1.3E-17 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1323 1374 9.2E-14 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 837 884 4.9E-14 T 29-03-2018 CXR48_RS03690 0d785fbcaa44bef146899b0b80a56322 2312 Gene3D G3DSA:2.160.20.50 1254 1322 1.1E-12 T 29-03-2018 CXR48_RS15525 e5e8aac11fca26d23c0c3e2efcf6c74c 408 SUPERFAMILY SSF52540 2 230 1.28E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS15525 e5e8aac11fca26d23c0c3e2efcf6c74c 408 Pfam PF00005 ABC transporter 18 166 7.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS15525 e5e8aac11fca26d23c0c3e2efcf6c74c 408 Gene3D G3DSA:3.40.50.300 1 249 6.7E-60 T 29-03-2018 CXR48_RS15525 e5e8aac11fca26d23c0c3e2efcf6c74c 408 SMART SM00382 26 270 9.9E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS05670 b012bbaa86dc7a40f56208f31ca34c98 300 Gene3D G3DSA:3.40.30.10 19 224 2.3E-28 T 29-03-2018 CXR48_RS05670 b012bbaa86dc7a40f56208f31ca34c98 300 Pfam PF13743 Thioredoxin 24 216 4.3E-73 T 29-03-2018 CXR48_RS05670 b012bbaa86dc7a40f56208f31ca34c98 300 SUPERFAMILY SSF52833 19 224 1.31E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS17865 498b80a58c7b3c006d17fa970abc8671 472 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CXR48_RS17865 498b80a58c7b3c006d17fa970abc8671 472 PIRSF PIRSF006060 1 470 8.8E-80 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS17865 498b80a58c7b3c006d17fa970abc8671 472 Pfam PF00324 Amino acid permease 18 461 3.6E-126 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS00020 0f5c2a7cad0e6300e12536b0aae9a36d 370 Gene3D G3DSA:3.40.50.300 1 360 2.9E-32 T 29-03-2018 CXR48_RS00020 0f5c2a7cad0e6300e12536b0aae9a36d 370 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CXR48_RS00020 0f5c2a7cad0e6300e12536b0aae9a36d 370 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 346 2.8E-19 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CXR48_RS00020 0f5c2a7cad0e6300e12536b0aae9a36d 370 SUPERFAMILY SSF52540 2 217 1.96E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00020 0f5c2a7cad0e6300e12536b0aae9a36d 370 SUPERFAMILY SSF52540 244 349 1.96E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS00020 0f5c2a7cad0e6300e12536b0aae9a36d 370 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 370 105.053 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CXR48_RS00020 0f5c2a7cad0e6300e12536b0aae9a36d 370 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 366 1.8E-142 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CXR48_RS00020 0f5c2a7cad0e6300e12536b0aae9a36d 370 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CXR48_RS02440 8ea7f4ef0b3f2c6d9ab48d70afad1e91 121 Pfam PF01740 STAS domain 12 101 1.0E-12 T 29-03-2018 IPR002645 STAS domain CXR48_RS02440 8ea7f4ef0b3f2c6d9ab48d70afad1e91 121 Gene3D G3DSA:3.30.750.24 3 121 2.6E-14 T 29-03-2018 IPR002645 STAS domain CXR48_RS02440 8ea7f4ef0b3f2c6d9ab48d70afad1e91 121 SUPERFAMILY SSF52091 5 115 4.32E-20 T 29-03-2018 IPR002645 STAS domain CXR48_RS04780 89b5d5a947e1c04a8ff7a6bd042042ef 238 SUPERFAMILY SSF51695 3 234 8.63E-72 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CXR48_RS04780 89b5d5a947e1c04a8ff7a6bd042042ef 238 Gene3D G3DSA:3.20.20.190 1 236 2.0E-73 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CXR48_RS04780 89b5d5a947e1c04a8ff7a6bd042042ef 238 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 232 9.3E-47 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CXR48_RS04460 9b0f07977ef7345bc59acbe5f450e7b4 244 Pfam PF04519 Polymer-forming cytoskeletal 10 89 1.9E-6 T 29-03-2018 IPR007607 Protein of unknown function DUF583 CXR48_RS04460 9b0f07977ef7345bc59acbe5f450e7b4 244 Pfam PF04519 Polymer-forming cytoskeletal 53 127 7.9E-9 T 29-03-2018 IPR007607 Protein of unknown function DUF583 CXR48_RS04460 9b0f07977ef7345bc59acbe5f450e7b4 244 Pfam PF04519 Polymer-forming cytoskeletal 70 142 3.2E-7 T 29-03-2018 IPR007607 Protein of unknown function DUF583 CXR48_RS05990 7db765371c6096248e42fc3e3f259e52 211 PRINTS PR01837 MgtC/SapB protein signature 92 116 2.9E-48 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS05990 7db765371c6096248e42fc3e3f259e52 211 PRINTS PR01837 MgtC/SapB protein signature 31 49 2.9E-48 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS05990 7db765371c6096248e42fc3e3f259e52 211 PRINTS PR01837 MgtC/SapB protein signature 65 87 2.9E-48 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS05990 7db765371c6096248e42fc3e3f259e52 211 PRINTS PR01837 MgtC/SapB protein signature 12 31 2.9E-48 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS05990 7db765371c6096248e42fc3e3f259e52 211 Pfam PF02308 MgtC family 9 136 1.3E-37 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS15900 0090d7a02387090474c382e77521302a 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 205 6.8E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15900 0090d7a02387090474c382e77521302a 217 Gene3D G3DSA:1.10.3720.10 2 209 4.2E-30 T 29-03-2018 CXR48_RS15900 0090d7a02387090474c382e77521302a 217 SUPERFAMILY SSF161098 13 197 2.35E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS05840 40faad361f1a6f54e4138d4a4da99b46 77 ProDom PD058861 TRANSCRIPTIONAL ABRB FAMILY REGULATOR AF0476 REGULATOR 11 66 0.001 T 29-03-2018 CXR48_RS05840 40faad361f1a6f54e4138d4a4da99b46 77 Gene3D G3DSA:2.10.260.10 12 56 7.3E-14 T 29-03-2018 CXR48_RS05840 40faad361f1a6f54e4138d4a4da99b46 77 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 12 53 8.4E-13 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS05840 40faad361f1a6f54e4138d4a4da99b46 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 13 44 9.9E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS05840 40faad361f1a6f54e4138d4a4da99b46 77 SMART SM00966 13 57 4.0E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CXR48_RS05840 40faad361f1a6f54e4138d4a4da99b46 77 SUPERFAMILY SSF89447 8 54 1.09E-11 T 29-03-2018 CXR48_RS15610 098393d2827c423154461ec04d0846d9 470 PIRSF PIRSF006060 1 469 1.8E-58 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS15610 098393d2827c423154461ec04d0846d9 470 Pfam PF13520 Amino acid permease 8 436 1.8E-56 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS15980 e900ba660c86ed3cc10202f61734a1f1 293 Gene3D G3DSA:3.40.630.30 106 286 2.6E-25 T 29-03-2018 CXR48_RS15980 e900ba660c86ed3cc10202f61734a1f1 293 SUPERFAMILY SSF55729 132 286 4.59E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS15980 e900ba660c86ed3cc10202f61734a1f1 293 Gene3D G3DSA:3.40.630.30 1 105 0.0024 T 29-03-2018 CXR48_RS15980 e900ba660c86ed3cc10202f61734a1f1 293 Pfam PF13480 Acetyltransferase (GNAT) domain 145 268 8.8E-10 T 29-03-2018 CXR48_RS01705 c5f2df3f7676c1a3eee1634d63a93987 484 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 151 176 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CXR48_RS01705 c5f2df3f7676c1a3eee1634d63a93987 484 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 409 429 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CXR48_RS01705 c5f2df3f7676c1a3eee1634d63a93987 484 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 2 480 1.5E-222 T 29-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 CXR48_RS01705 c5f2df3f7676c1a3eee1634d63a93987 484 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 29 427 8.6E-101 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS01705 c5f2df3f7676c1a3eee1634d63a93987 484 Pfam PF00474 Sodium:solute symporter family 29 427 2.1E-109 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CXR48_RS16695 d904962083e7ad745bdabbd1693f66e4 225 Gene3D G3DSA:3.40.50.2020 38 225 5.1E-24 T 29-03-2018 CXR48_RS16695 d904962083e7ad745bdabbd1693f66e4 225 SUPERFAMILY SSF53271 68 224 5.64E-20 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CXR48_RS16695 d904962083e7ad745bdabbd1693f66e4 225 Pfam PF00156 Phosphoribosyl transferase domain 140 223 1.0E-7 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CXR48_RS06430 63601812b55b114012aca326442ab1d6 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 4.6E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS06430 63601812b55b114012aca326442ab1d6 308 SUPERFAMILY SSF161098 90 291 1.1E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS06430 63601812b55b114012aca326442ab1d6 308 Gene3D G3DSA:1.10.3720.10 2 292 4.6E-43 T 29-03-2018 CXR48_RS07440 2c9a83d207479ffead3808c65630381f 294 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 3 277 1.9E-120 T 29-03-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG CXR48_RS07440 2c9a83d207479ffead3808c65630381f 294 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 28 275 6.1E-63 T 29-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CXR48_RS07660 be2939c89123cf3cca8dfe1d0a3cc1bd 150 Pfam PF04472 Cell division protein SepF 63 134 3.4E-31 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CXR48_RS07660 be2939c89123cf3cca8dfe1d0a3cc1bd 150 Hamap MF_01197 Cell division protein SepF [sepF]. 1 142 20.131 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 CXR48_RS14520 909277d58fb078199978b61639432a76 343 Gene3D G3DSA:3.20.20.70 2 343 7.0E-53 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CXR48_RS14520 909277d58fb078199978b61639432a76 343 Pfam PF03060 Nitronate monooxygenase 5 342 1.7E-97 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CXR48_RS14520 909277d58fb078199978b61639432a76 343 SUPERFAMILY SSF51412 109 338 4.58E-58 T 29-03-2018 CXR48_RS14520 909277d58fb078199978b61639432a76 343 SUPERFAMILY SSF51412 7 74 4.58E-58 T 29-03-2018 CXR48_RS13105 2e6dbf864c37a37555d9d188ca47bf2d 146 Gene3D G3DSA:1.10.10.10 5 112 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13105 2e6dbf864c37a37555d9d188ca47bf2d 146 SUPERFAMILY SSF46785 14 143 2.97E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13105 2e6dbf864c37a37555d9d188ca47bf2d 146 Gene3D G3DSA:1.10.287.100 113 146 5.8E-4 T 29-03-2018 CXR48_RS13105 2e6dbf864c37a37555d9d188ca47bf2d 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.1E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS13105 2e6dbf864c37a37555d9d188ca47bf2d 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.1E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS13105 2e6dbf864c37a37555d9d188ca47bf2d 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.1E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS13105 2e6dbf864c37a37555d9d188ca47bf2d 146 Pfam PF01047 MarR family 36 94 3.2E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS13105 2e6dbf864c37a37555d9d188ca47bf2d 146 SMART SM00347 29 129 5.2E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CXR48_RS02090 97d491de51552b471315109c7f144378 254 SUPERFAMILY SSF88713 3 251 7.34E-101 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CXR48_RS02090 97d491de51552b471315109c7f144378 254 Gene3D G3DSA:3.20.20.370 3 250 6.2E-107 T 29-03-2018 CXR48_RS02090 97d491de51552b471315109c7f144378 254 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 46.414 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CXR48_RS02090 97d491de51552b471315109c7f144378 254 Pfam PF03746 LamB/YcsF family 4 242 3.0E-103 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CXR48_RS09165 3c4c63267ddc1ea3f37ae7d3d91ed788 256 Pfam PF03744 6-carboxyhexanoate--CoA ligase 7 250 3.5E-82 T 29-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 CXR48_RS09165 3c4c63267ddc1ea3f37ae7d3d91ed788 256 ProDom PD017229 LIGASE SYNTHASE BIOTIN MAGNESIUM PIMELOYL-COA 6-CARBOXYHEXANOATE--COA BIOSYNTHESIS 6-CARBOXYHEXANOATE-COA BIOW COA 7 224 8.0E-124 T 29-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 CXR48_RS09165 3c4c63267ddc1ea3f37ae7d3d91ed788 256 Hamap MF_00668 6-carboxyhexanoate--CoA ligase [bioW]. 6 251 55.92 T 29-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 CXR48_RS09165 3c4c63267ddc1ea3f37ae7d3d91ed788 256 TIGRFAM TIGR01204 bioW: 6-carboxyhexanoate--CoA ligase 20 251 4.9E-89 T 29-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 CXR48_RS18390 4e616202d169342b501fb5c8d101bf06 468 PIRSF PIRSF006446 1 468 8.0E-192 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CXR48_RS18390 4e616202d169342b501fb5c8d101bf06 468 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 442 3.9E-170 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CXR48_RS18675 01c9c01e6e0813f0f3ca56edb72a118d 325 Gene3D G3DSA:3.30.565.10 133 321 2.0E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18675 01c9c01e6e0813f0f3ca56edb72a118d 325 SMART SM00387 213 325 1.8E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18675 01c9c01e6e0813f0f3ca56edb72a118d 325 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 214 321 1.8E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18675 01c9c01e6e0813f0f3ca56edb72a118d 325 SUPERFAMILY SSF55874 158 321 1.38E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS18675 01c9c01e6e0813f0f3ca56edb72a118d 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 303 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS18675 01c9c01e6e0813f0f3ca56edb72a118d 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 251 265 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS18675 01c9c01e6e0813f0f3ca56edb72a118d 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 269 279 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS18675 01c9c01e6e0813f0f3ca56edb72a118d 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 322 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CXR48_RS06315 2ad284b55792000ad728a541a3820739 88 ProDom PD028957 PBSX RELATED XKDR ELEMENT LIN1285 PHAGE PHAGE-LIKE YQBR 3 88 2.0E-27 T 29-03-2018 IPR022555 Protein of unknown function, DUF2577 CXR48_RS06315 2ad284b55792000ad728a541a3820739 88 Pfam PF10844 Protein of unknown function (DUF2577) 7 59 2.5E-6 T 29-03-2018 IPR022555 Protein of unknown function, DUF2577 CXR48_RS08150 2d2bd87bc849accbe3770b249b64a4c0 217 Pfam PF04347 Flagellar biosynthesis protein, FliO 102 198 7.8E-12 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CXR48_RS14990 cd9557cca3084e5f3ee4e0406d4e531f 111 Pfam PF09221 Bacteriocin class IId cyclical uberolysin-like 49 111 2.6E-20 T 29-03-2018 IPR020038 Circular bacteriocin, circularin A/uberolysin family CXR48_RS14990 cd9557cca3084e5f3ee4e0406d4e531f 111 Gene3D G3DSA:1.20.225.10 49 111 9.1E-19 T 29-03-2018 CXR48_RS14990 cd9557cca3084e5f3ee4e0406d4e531f 111 TIGRFAM TIGR03651 circ_ocin_uber: circular bacteriocin, circularin A/uberolysin family 46 111 3.5E-20 T 29-03-2018 IPR020038 Circular bacteriocin, circularin A/uberolysin family CXR48_RS13485 08e436bdb94c5ad816d699ea13686a04 154 Pfam PF04284 Protein of unknown function (DUF441) 7 146 1.3E-47 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CXR48_RS13485 08e436bdb94c5ad816d699ea13686a04 154 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 149 18.999 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CXR48_RS13485 08e436bdb94c5ad816d699ea13686a04 154 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 21 131 1.0E-41 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CXR48_RS15530 074d5bd7b8ad8b41d9ce0d33faa9a8df 348 Gene3D G3DSA:1.10.3470.10 9 347 5.3E-72 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS15530 074d5bd7b8ad8b41d9ce0d33faa9a8df 348 SUPERFAMILY SSF81345 9 340 6.54E-79 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS15530 074d5bd7b8ad8b41d9ce0d33faa9a8df 348 Pfam PF01032 FecCD transport family 25 340 5.3E-88 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CXR48_RS08165 15bbcbc27f20cf102f2b5daf884fff15 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 75 94 2.4E-29 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CXR48_RS08165 15bbcbc27f20cf102f2b5daf884fff15 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 17 38 2.4E-29 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CXR48_RS08165 15bbcbc27f20cf102f2b5daf884fff15 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 178 200 2.4E-29 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CXR48_RS08165 15bbcbc27f20cf102f2b5daf884fff15 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 200 219 2.4E-29 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CXR48_RS08165 15bbcbc27f20cf102f2b5daf884fff15 259 Pfam PF01311 Bacterial export proteins, family 1 9 243 1.1E-72 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CXR48_RS08165 15bbcbc27f20cf102f2b5daf884fff15 259 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 10 253 3.6E-69 T 29-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 CXR48_RS11370 6285a4771019fa5b973bfd9b1856ae36 454 ProSitePatterns PS00455 Putative AMP-binding domain signature. 141 152 - T 29-03-2018 IPR020845 AMP-binding, conserved site CXR48_RS11370 6285a4771019fa5b973bfd9b1856ae36 454 SUPERFAMILY SSF56801 12 452 5.89E-79 T 29-03-2018 CXR48_RS11370 6285a4771019fa5b973bfd9b1856ae36 454 Gene3D G3DSA:3.40.50.980 144 296 4.1E-32 T 29-03-2018 CXR48_RS11370 6285a4771019fa5b973bfd9b1856ae36 454 Gene3D G3DSA:3.40.50.980 9 143 2.0E-13 T 29-03-2018 CXR48_RS11370 6285a4771019fa5b973bfd9b1856ae36 454 Gene3D G3DSA:3.30.300.30 358 453 1.9E-14 T 29-03-2018 CXR48_RS11370 6285a4771019fa5b973bfd9b1856ae36 454 Gene3D G3DSA:2.30.38.10 297 357 1.3E-7 T 29-03-2018 CXR48_RS11370 6285a4771019fa5b973bfd9b1856ae36 454 Pfam PF13193 AMP-binding enzyme C-terminal domain 372 441 2.0E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CXR48_RS11370 6285a4771019fa5b973bfd9b1856ae36 454 Pfam PF00501 AMP-binding enzyme 15 363 3.9E-49 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CXR48_RS14805 6f578d039476dcea4f3102553a571046 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 3.8E-24 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CXR48_RS06160 66ed8e883f0b3a2720d4ebe7ec825eec 155 SUPERFAMILY SSF109854 1 151 7.94E-35 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CXR48_RS06160 66ed8e883f0b3a2720d4ebe7ec825eec 155 Pfam PF05163 DinB family 4 151 1.5E-32 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CXR48_RS06160 66ed8e883f0b3a2720d4ebe7ec825eec 155 Gene3D G3DSA:1.20.120.450 1 145 6.2E-21 T 29-03-2018 CXR48_RS12900 1dac14f453f95a366c96458d4da133dd 172 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 7 159 1.2E-28 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CXR48_RS12900 1dac14f453f95a366c96458d4da133dd 172 Pfam PF04093 rod shape-determining protein MreD 2 162 1.9E-40 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CXR48_RS05970 0e9809c60501e1f4ecac0faff1074242 227 Gene3D G3DSA:1.10.150.240 17 74 2.4E-11 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CXR48_RS05970 0e9809c60501e1f4ecac0faff1074242 227 Gene3D G3DSA:3.40.50.1000 75 226 5.9E-21 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS05970 0e9809c60501e1f4ecac0faff1074242 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 74 188 2.8E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CXR48_RS05970 0e9809c60501e1f4ecac0faff1074242 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 188 1.0E-22 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS05970 0e9809c60501e1f4ecac0faff1074242 227 SUPERFAMILY SSF56784 1 197 1.62E-38 T 29-03-2018 IPR023214 HAD-like domain CXR48_RS16580 9f40a7610e2b1a2879a697513bb840b4 111 ProDom PD072806 SWRA MOTILITY YVZD SWARMING MOTILITY-SWARMING 1 111 5.0E-53 T 29-03-2018 IPR035388 Swarming motility protein SwrA CXR48_RS16580 9f40a7610e2b1a2879a697513bb840b4 111 Pfam PF17423 Swarming motility protein 1 109 8.0E-52 T 29-03-2018 IPR035388 Swarming motility protein SwrA CXR48_RS06365 38660da524b07615c12c8df23aa44750 87 ProDom PD008023 HOLIN TRANSMEMBRANE MEMBRANE PROPHAGE FAMILY BHLB SPP1 5'REGION HOLIN ORF050 5 87 1.0E-20 T 29-03-2018 IPR006479 Holin CXR48_RS06365 38660da524b07615c12c8df23aa44750 87 Pfam PF04688 SPP1 phage holin 5 81 4.7E-29 T 29-03-2018 IPR006479 Holin CXR48_RS06365 38660da524b07615c12c8df23aa44750 87 TIGRFAM TIGR01592 holin_SPP1: holin, SPP1 family 5 84 5.8E-31 T 29-03-2018 IPR006479 Holin CXR48_RS18600 6bf397661f07dd241afb3cd466f84d0f 472 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CXR48_RS18600 6bf397661f07dd241afb3cd466f84d0f 472 Pfam PF00324 Amino acid permease 18 460 2.9E-129 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS18600 6bf397661f07dd241afb3cd466f84d0f 472 PIRSF PIRSF006060 1 469 1.6E-78 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS16135 083d1e7e183b284d1a53809ffc5a2cad 321 Pfam PF04230 Polysaccharide pyruvyl transferase 37 288 4.3E-23 T 29-03-2018 IPR007345 Polysaccharide pyruvyl transferase CXR48_RS05790 eead0c0c29bd56996cd64c050163152e 128 Pfam PF07552 Spore Coat Protein X and V domain 71 127 1.8E-6 T 29-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CXR48_RS05790 eead0c0c29bd56996cd64c050163152e 128 Pfam PF07552 Spore Coat Protein X and V domain 6 63 1.3E-16 T 29-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CXR48_RS17850 d3d241294dd0f8d7237cfb05fdf60661 204 Gene3D G3DSA:3.40.190.10 15 80 3.9E-4 T 29-03-2018 CXR48_RS17850 d3d241294dd0f8d7237cfb05fdf60661 204 Gene3D G3DSA:3.40.190.10 106 184 1.7E-6 T 29-03-2018 CXR48_RS17850 d3d241294dd0f8d7237cfb05fdf60661 204 SUPERFAMILY SSF53850 22 183 1.47E-9 T 29-03-2018 CXR48_RS11095 46da6c3f2010c8ae36d774269bc77741 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 4.1E-54 T 29-03-2018 IPR014204 Sporulation stage V, protein AE CXR48_RS11095 46da6c3f2010c8ae36d774269bc77741 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 2 111 2.1E-40 T 29-03-2018 IPR005562 SpoVA CXR48_RS12530 de3907ae186dbe1ce0eb750e4d97207a 76 ProDom PD057834 YRHC TRANSMEMBRANE MEMBRANE 1 76 5.0E-29 T 29-03-2018 IPR025418 YrhC-like protein CXR48_RS12530 de3907ae186dbe1ce0eb750e4d97207a 76 Pfam PF14143 YrhC-like protein 4 75 1.8E-27 T 29-03-2018 IPR025418 YrhC-like protein CXR48_RS05590 d9b37f2098587da518d19a516e2e8fde 316 Gene3D G3DSA:1.10.3720.10 2 304 1.4E-49 T 29-03-2018 CXR48_RS05590 d9b37f2098587da518d19a516e2e8fde 316 SUPERFAMILY SSF161098 90 303 5.63E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS05590 d9b37f2098587da518d19a516e2e8fde 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 315 2.9E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS05780 f5339b16d6f8acef0b167efa084fbd93 166 Pfam PF07552 Spore Coat Protein X and V domain 46 101 3.2E-17 T 29-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CXR48_RS05780 f5339b16d6f8acef0b167efa084fbd93 166 Pfam PF07552 Spore Coat Protein X and V domain 108 163 3.0E-17 T 29-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CXR48_RS11940 5582397dd92dd4d96ff94311ca94c803 320 Pfam PF00480 ROK family 7 312 1.3E-76 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CXR48_RS11940 5582397dd92dd4d96ff94311ca94c803 320 ProSitePatterns PS01125 ROK family signature. 137 164 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CXR48_RS11940 5582397dd92dd4d96ff94311ca94c803 320 Gene3D G3DSA:3.30.420.40 123 318 1.8E-58 T 29-03-2018 CXR48_RS11940 5582397dd92dd4d96ff94311ca94c803 320 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 320 7.4E-144 T 29-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CXR48_RS11940 5582397dd92dd4d96ff94311ca94c803 320 Gene3D G3DSA:3.30.420.40 1 122 3.8E-31 T 29-03-2018 CXR48_RS11940 5582397dd92dd4d96ff94311ca94c803 320 SUPERFAMILY SSF53067 6 313 8.4E-70 T 29-03-2018 CXR48_RS17695 696250d8938625b0f45f1d194b8ca0a4 170 Pfam PF01944 Stage II sporulation protein M 20 163 7.8E-25 T 29-03-2018 IPR002798 Stage II sporulation protein M-like CXR48_RS18240 680950c296e8c214a886a5f4947896fe 393 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 143 376 2.3E-15 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CXR48_RS18240 680950c296e8c214a886a5f4947896fe 393 PIRSF PIRSF500216 1 393 3.3E-168 T 29-03-2018 IPR024024 D-alanyl transfer protein DltB CXR48_RS18240 680950c296e8c214a886a5f4947896fe 393 PIRSF PIRSF016636 2 392 6.3E-86 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CXR48_RS18240 680950c296e8c214a886a5f4947896fe 393 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 3 389 3.7E-158 T 29-03-2018 IPR024024 D-alanyl transfer protein DltB CXR48_RS04040 f0063f1e53b98f1a5764d5038b05c2f6 183 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 3.5E-16 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CXR48_RS04040 f0063f1e53b98f1a5764d5038b05c2f6 183 SUPERFAMILY SSF46785 4 181 1.7E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS04040 f0063f1e53b98f1a5764d5038b05c2f6 183 Pfam PF10400 Virulence activator alpha C-term 94 180 1.6E-18 T 29-03-2018 IPR018309 Transcription regulator PadR, C-terminal CXR48_RS04040 f0063f1e53b98f1a5764d5038b05c2f6 183 Gene3D G3DSA:1.10.10.10 1 89 2.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS13865 30af0d368a60d95e8c69e59943a27e30 281 Gene3D G3DSA:3.60.15.10 4 269 2.3E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS13865 30af0d368a60d95e8c69e59943a27e30 281 SUPERFAMILY SSF56281 4 262 4.71E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS13865 30af0d368a60d95e8c69e59943a27e30 281 SMART SM00849 50 257 3.6E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS13865 30af0d368a60d95e8c69e59943a27e30 281 Pfam PF00753 Metallo-beta-lactamase superfamily 54 257 2.3E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase CXR48_RS01875 34e919543f5e7deb3ba80214ebd643db 546 PIRSF PIRSF005690 33 523 2.9E-198 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS01875 34e919543f5e7deb3ba80214ebd643db 546 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 48 508 2.6E-194 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CXR48_RS09225 56919e12724d6d938e69fe186233b783 126 Pfam PF07098 Protein of unknown function (DUF1360) 11 107 1.5E-31 T 29-03-2018 IPR010773 Mycobacterium phage PG1, Gp7 CXR48_RS13600 23f9b2d5cc664fe27741d7270a1d115d 146 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 124 2.3E-29 T 29-03-2018 IPR014229 Sporulation protein YtfJ CXR48_RS13600 23f9b2d5cc664fe27741d7270a1d115d 146 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 134 3.6E-59 T 29-03-2018 IPR014229 Sporulation protein YtfJ CXR48_RS13600 23f9b2d5cc664fe27741d7270a1d115d 146 PIRSF PIRSF021377 1 145 2.9E-62 T 29-03-2018 IPR014229 Sporulation protein YtfJ CXR48_RS01390 39fea1207f2915bc0a88430414af1287 206 Pfam PF00881 Nitroreductase family 9 184 4.0E-26 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CXR48_RS01390 39fea1207f2915bc0a88430414af1287 206 SUPERFAMILY SSF55469 2 204 1.31E-48 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS01390 39fea1207f2915bc0a88430414af1287 206 Gene3D G3DSA:3.40.109.10 1 206 6.1E-44 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CXR48_RS13400 9b4bd81eaabc2717d461394981d1b707 152 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 152 84.028 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CXR48_RS13400 9b4bd81eaabc2717d461394981d1b707 152 Pfam PF03477 ATP cone domain 50 136 2.1E-17 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CXR48_RS13400 9b4bd81eaabc2717d461394981d1b707 152 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 2.7E-74 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CXR48_RS00195 b27d3dce82cca71329c2b70afc0cbc3f 378 Pfam PF05816 Toxic anion resistance protein (TelA) 35 363 1.4E-115 T 29-03-2018 IPR008863 Toxic anion resistance CXR48_RS00195 b27d3dce82cca71329c2b70afc0cbc3f 378 PIRSF PIRSF026508 2 370 1.1E-117 T 29-03-2018 IPR008863 Toxic anion resistance CXR48_RS14400 2795aa9fd8ed44a3117884ca347bf00d 509 SMART SM00244 119 301 4.1E-15 T 29-03-2018 IPR001107 Band 7 domain CXR48_RS14400 2795aa9fd8ed44a3117884ca347bf00d 509 SUPERFAMILY SSF117892 68 210 1.31E-34 T 29-03-2018 IPR001107 Band 7 domain CXR48_RS14400 2795aa9fd8ed44a3117884ca347bf00d 509 Pfam PF01145 SPFH domain / Band 7 family 30 219 9.5E-25 T 29-03-2018 IPR001107 Band 7 domain CXR48_RS14400 2795aa9fd8ed44a3117884ca347bf00d 509 Pfam PF15975 Flotillin 368 459 1.9E-14 T 29-03-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CXR48_RS11090 f1227f67cf62261619930b41a99462d6 202 Pfam PF14097 Stage V sporulation protein AE1 6 185 8.6E-84 T 29-03-2018 IPR025914 Stage V sporulation protein AE CXR48_RS11590 7c706eb846f9bed640ccc746144ccd22 208 SUPERFAMILY SSF53187 30 205 2.01E-52 T 29-03-2018 CXR48_RS11590 7c706eb846f9bed640ccc746144ccd22 208 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 33 202 7.1E-53 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS11590 7c706eb846f9bed640ccc746144ccd22 208 Gene3D G3DSA:3.40.630.40 19 206 1.6E-60 T 29-03-2018 CXR48_RS11590 7c706eb846f9bed640ccc746144ccd22 208 SMART SM00646 91 202 1.9E-45 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CXR48_RS16830 d697082f65f4bf908b7d9a0f4152a3b7 129 SUPERFAMILY SSF52374 1 125 1.23E-35 T 29-03-2018 CXR48_RS16830 d697082f65f4bf908b7d9a0f4152a3b7 129 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 3.9E-70 T 29-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 CXR48_RS16830 d697082f65f4bf908b7d9a0f4152a3b7 129 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 68 6.8E-22 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CXR48_RS16830 d697082f65f4bf908b7d9a0f4152a3b7 129 Pfam PF01467 Cytidylyltransferase-like 5 124 2.6E-23 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CXR48_RS16830 d697082f65f4bf908b7d9a0f4152a3b7 129 Gene3D G3DSA:3.40.50.620 1 129 1.6E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CXR48_RS17110 a0080364a5fd747c411daac4aa055ab6 86 Pfam PF17279 Family of unknown function (DUF5344) 1 84 3.2E-22 T 29-03-2018 CXR48_RS17110 a0080364a5fd747c411daac4aa055ab6 86 ProDom PD061728 YWQI YWQIA COIL COILED 1 86 4.0E-26 T 29-03-2018 IPR020299 Uncharacterised protein family YwqI CXR48_RS16880 be83e8fe983ab4fe790199e08156c900 328 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 95 243 3.6E-42 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CXR48_RS16880 be83e8fe983ab4fe790199e08156c900 328 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 94 243 7.9E-37 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CXR48_RS04160 560c835e78a6626dea0bae8ae03ed454 326 Gene3D G3DSA:3.90.550.10 4 241 6.4E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS04160 560c835e78a6626dea0bae8ae03ed454 326 SUPERFAMILY SSF53448 3 249 2.3E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS04160 560c835e78a6626dea0bae8ae03ed454 326 Pfam PF00535 Glycosyl transferase family 2 7 168 2.8E-34 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS05015 611bf74c84e455f2b466e85a10ab385a 247 SUPERFAMILY SSF52540 3 230 2.11E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS05015 611bf74c84e455f2b466e85a10ab385a 247 Pfam PF00005 ABC transporter 19 162 1.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CXR48_RS05015 611bf74c84e455f2b466e85a10ab385a 247 SMART SM00382 28 213 2.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CXR48_RS05015 611bf74c84e455f2b466e85a10ab385a 247 Gene3D G3DSA:3.40.50.300 1 244 2.7E-59 T 29-03-2018 CXR48_RS19185 398a63420d48a3b781b0cc7f3f06fe38 169 Gene3D G3DSA:1.20.120.450 6 166 2.7E-23 T 29-03-2018 CXR48_RS19185 398a63420d48a3b781b0cc7f3f06fe38 169 SUPERFAMILY SSF109854 6 150 2.56E-29 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CXR48_RS19185 398a63420d48a3b781b0cc7f3f06fe38 169 Pfam PF05163 DinB family 7 166 3.1E-39 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CXR48_RS08260 28035428b8f101f51c53b06b397a88c2 422 SMART SM00228 190 260 2.8E-4 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS08260 28035428b8f101f51c53b06b397a88c2 422 SUPERFAMILY SSF50156 175 269 1.25E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS08260 28035428b8f101f51c53b06b397a88c2 422 Pfam PF13180 PDZ domain 210 267 2.2E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CXR48_RS08260 28035428b8f101f51c53b06b397a88c2 422 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 1 421 3.9E-157 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CXR48_RS08260 28035428b8f101f51c53b06b397a88c2 422 Pfam PF02163 Peptidase family M50 8 408 3.7E-84 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CXR48_RS08260 28035428b8f101f51c53b06b397a88c2 422 Gene3D G3DSA:2.30.42.10 149 281 1.1E-17 T 29-03-2018 CXR48_RS16335 9c4bd7d21791d376ee02ee77d3c1f491 529 Pfam PF00916 Sulfate permease family 15 379 1.4E-100 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CXR48_RS16335 9c4bd7d21791d376ee02ee77d3c1f491 529 SUPERFAMILY SSF52091 426 522 2.16E-18 T 29-03-2018 IPR002645 STAS domain CXR48_RS16335 9c4bd7d21791d376ee02ee77d3c1f491 529 Gene3D G3DSA:3.30.750.24 413 526 1.7E-21 T 29-03-2018 IPR002645 STAS domain CXR48_RS16335 9c4bd7d21791d376ee02ee77d3c1f491 529 Pfam PF01740 STAS domain 425 524 2.7E-20 T 29-03-2018 IPR002645 STAS domain CXR48_RS11065 44e6ac6bcf7a821387afacd763a49083 163 Pfam PF07301 Protein of unknown function (DUF1453) 6 158 4.0E-30 T 29-03-2018 IPR009916 Protein of unknown function DUF1453 CXR48_RS17445 ee78ec989cebb276baef46df5b1a97b6 415 Gene3D G3DSA:3.40.640.10 33 269 1.6E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS17445 ee78ec989cebb276baef46df5b1a97b6 415 Pfam PF00464 Serine hydroxymethyltransferase 6 380 2.9E-185 T 29-03-2018 CXR48_RS17445 ee78ec989cebb276baef46df5b1a97b6 415 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 53.339 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CXR48_RS17445 ee78ec989cebb276baef46df5b1a97b6 415 PIRSF PIRSF000412 1 414 3.2E-172 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CXR48_RS17445 ee78ec989cebb276baef46df5b1a97b6 415 Gene3D G3DSA:3.90.1150.10 270 410 2.8E-58 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CXR48_RS17445 ee78ec989cebb276baef46df5b1a97b6 415 SUPERFAMILY SSF53383 2 411 1.31E-181 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS17445 ee78ec989cebb276baef46df5b1a97b6 415 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CXR48_RS06770 4e92c068d662bf6671bc419958ce9229 261 Gene3D G3DSA:3.30.1330.60 75 261 4.5E-38 T 29-03-2018 IPR006665 OmpA-like domain CXR48_RS06770 4e92c068d662bf6671bc419958ce9229 261 Pfam PF00691 OmpA family 144 244 9.6E-15 T 29-03-2018 IPR006665 OmpA-like domain CXR48_RS06770 4e92c068d662bf6671bc419958ce9229 261 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 58 4.8E-22 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CXR48_RS06770 4e92c068d662bf6671bc419958ce9229 261 SUPERFAMILY SSF103088 131 252 6.67E-28 T 29-03-2018 IPR006665 OmpA-like domain CXR48_RS10340 22d3c234ecb8863f70e710a25a7391dd 70 Gene3D G3DSA:1.10.1660.10 10 68 2.1E-6 T 29-03-2018 CXR48_RS10340 22d3c234ecb8863f70e710a25a7391dd 70 Pfam PF12728 Helix-turn-helix domain 21 70 7.3E-8 T 29-03-2018 CXR48_RS10340 22d3c234ecb8863f70e710a25a7391dd 70 SUPERFAMILY SSF46955 20 66 1.65E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS10660 f038dbed6f592f040bb8dee79f939202 111 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 104 3.7E-21 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CXR48_RS10660 f038dbed6f592f040bb8dee79f939202 111 SUPERFAMILY SSF101386 4 104 3.27E-29 T 29-03-2018 CXR48_RS10660 f038dbed6f592f040bb8dee79f939202 111 PIRSF PIRSF029904 1 111 2.5E-55 T 29-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD CXR48_RS10660 f038dbed6f592f040bb8dee79f939202 111 Gene3D G3DSA:1.10.3420.10 2 111 8.0E-30 T 29-03-2018 CXR48_RS09070 30662d5c3dd570cd059e08c8dbed3102 103 Pfam PF09685 Domain of unknown function (DUF4870) 5 95 7.4E-9 T 29-03-2018 IPR019109 Protein of unknown function DUF4870 CXR48_RS09070 30662d5c3dd570cd059e08c8dbed3102 103 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 99 5.0E-28 T 29-03-2018 CXR48_RS06245 4ca8c4e6ba0fb02184567b47d1dd03a1 281 Pfam PF14550 Putative phage serine protease XkdF 41 158 1.4E-45 T 29-03-2018 IPR027924 Phage-like element PBSX protein, XkdF CXR48_RS06325 8cde22310b0a72bedf0feeca729c94f6 348 Pfam PF04865 Baseplate J-like protein 62 306 1.7E-63 T 29-03-2018 IPR006949 Baseplate protein J-like CXR48_RS04530 f136227172b88e08bef300dc211e63e1 315 Pfam PF12679 ABC-2 family transporter protein 7 313 1.3E-18 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CXR48_RS16235 6d7a6e2c3d8e29560933a113529e75ce 172 Gene3D G3DSA:3.40.630.30 1 172 1.5E-33 T 29-03-2018 CXR48_RS16235 6d7a6e2c3d8e29560933a113529e75ce 172 Pfam PF00583 Acetyltransferase (GNAT) family 29 147 1.3E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS16235 6d7a6e2c3d8e29560933a113529e75ce 172 SUPERFAMILY SSF55729 1 164 4.15E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS10310 706ee6bb24f8627c5905bb58dfacd22f 426 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 42 379 2.9E-83 T 29-03-2018 IPR006427 Phage portal protein, HK97 CXR48_RS10310 706ee6bb24f8627c5905bb58dfacd22f 426 Pfam PF04860 Phage portal protein 50 374 1.1E-90 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CXR48_RS03780 bd3b90043c47a4b084722c53d9020dfd 147 Pfam PF10787 Uncharacterised protein from bacillus cereus group 2 141 1.3E-64 T 29-03-2018 IPR019723 Uncharacterised protein, YfmQ CXR48_RS01005 c9a9adfb77dd3c3356e1d9a2d804988b 340 Pfam PF01032 FecCD transport family 15 333 5.1E-83 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CXR48_RS01005 c9a9adfb77dd3c3356e1d9a2d804988b 340 Gene3D G3DSA:1.10.3470.10 1 339 8.3E-65 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS01005 c9a9adfb77dd3c3356e1d9a2d804988b 340 SUPERFAMILY SSF81345 4 333 3.14E-75 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS10945 9959b2d516319930282923624b9b65ff 353 ProDom PD136539 TRANSCRIPTION SIGMA-X NEGATIVE ACTIVITY RSIX REPRESSOR MEMBRANE EFFECTOR REGULATION REGULATOR 1 348 2.0E-51 T 29-03-2018 CXR48_RS15205 784c007a0c325708455f7d21af1de434 292 Gene3D G3DSA:1.20.58.370 1 39 1.4E-4 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CXR48_RS15205 784c007a0c325708455f7d21af1de434 292 SUPERFAMILY SSF161098 50 281 6.28E-59 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS15205 784c007a0c325708455f7d21af1de434 292 Gene3D G3DSA:1.10.3720.10 57 289 3.8E-44 T 29-03-2018 CXR48_RS15205 784c007a0c325708455f7d21af1de434 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 282 3.7E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS13195 fc6b55afae464c3d2db677449bc50544 134 Pfam PF03994 Domain of Unknown Function (DUF350) 80 134 1.0E-15 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CXR48_RS13195 fc6b55afae464c3d2db677449bc50544 134 Pfam PF03994 Domain of Unknown Function (DUF350) 15 68 3.4E-12 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CXR48_RS03070 59484e8f67250501304d1fa59fa92020 63 Pfam PF14146 Domain of unknown function (DUF4305) 17 52 6.8E-13 T 29-03-2018 IPR025426 Protein of unknown function DUF4305 CXR48_RS03070 59484e8f67250501304d1fa59fa92020 63 ProDom PD053380 YDIK LIPOPROTEIN TRANSMEMBRANE MEMBRANE PRECURSOR PALMITATE SIGNAL 1 63 2.0E-28 T 29-03-2018 CXR48_RS04665 79b5b7b982973ef949f56fafd00580ca 107 Pfam PF13028 Protein of unknown function (DUF3889) 19 106 9.9E-28 T 29-03-2018 IPR024987 Protein of unknown function DUF3889 CXR48_RS05600 55de7bcbd5b7bb29c4713411fd23347a 250 Pfam PF12227 Protein of unknown function (DUF3603) 35 250 2.3E-109 T 29-03-2018 IPR020909 UPF0736 CXR48_RS05600 55de7bcbd5b7bb29c4713411fd23347a 250 Hamap MF_01860 UPF0736 protein . 1 250 50.553 T 29-03-2018 IPR020909 UPF0736 CXR48_RS10405 0dbaef2c71d13c58effb919645ac67f0 245 Pfam PF12684 PDDEXK-like domain of unknown function (DUF3799) 2 231 3.1E-79 T 29-03-2018 IPR024432 Putative exodeoxyribonuclease 8, PDDEXK-like domain CXR48_RS12115 d5e2e257fee0ff11dfebb773f0816674 270 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 268 60.503 T 29-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CXR48_RS12115 d5e2e257fee0ff11dfebb773f0816674 270 Pfam PF03618 Kinase/pyrophosphorylase 6 262 2.5E-96 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CXR48_RS12620 051a16b8116c7acefd045da85c72b9b9 353 Pfam PF01594 AI-2E family transporter 20 342 3.8E-83 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CXR48_RS07675 18349101a8318981f94c055cec34ab0a 164 Pfam PF05103 DivIVA protein 3 133 3.5E-48 T 29-03-2018 IPR007793 DivIVA family CXR48_RS07675 18349101a8318981f94c055cec34ab0a 164 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 1.5E-15 T 29-03-2018 IPR019933 DivIVA domain CXR48_RS11560 911bbc67c32e4911850af2cb0039deb5 482 Gene3D G3DSA:1.10.4100.10 392 482 1.7E-12 T 29-03-2018 CXR48_RS11560 911bbc67c32e4911850af2cb0039deb5 482 SUPERFAMILY SSF103378 14 480 2.62E-156 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CXR48_RS11560 911bbc67c32e4911850af2cb0039deb5 482 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 15 482 1.6E-258 T 29-03-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 CXR48_RS11560 911bbc67c32e4911850af2cb0039deb5 482 Pfam PF03972 MmgE/PrpD family 19 462 1.5E-151 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CXR48_RS11560 911bbc67c32e4911850af2cb0039deb5 482 Gene3D G3DSA:1.10.4100.10 1 330 8.4E-96 T 29-03-2018 CXR48_RS14870 9e97bc9f11aa11b84932dbd88c238b92 225 Pfam PF10042 Uncharacterized conserved protein (DUF2278) 1 212 5.9E-70 T 29-03-2018 IPR019268 Protein of unknown function DUF2278 CXR48_RS17950 699c855c24717e8e8c4dbdc9b1f56464 123 Pfam PF04241 Protein of unknown function (DUF423) 18 105 1.2E-32 T 29-03-2018 IPR006696 Protein of unknown function DUF423 CXR48_RS12995 faf43944c468d461693fe45eaeb574f0 195 Pfam PF01926 50S ribosome-binding GTPase 25 143 3.2E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CXR48_RS12995 faf43944c468d461693fe45eaeb574f0 195 Gene3D G3DSA:3.40.50.300 3 195 3.3E-30 T 29-03-2018 CXR48_RS12995 faf43944c468d461693fe45eaeb574f0 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 29.26 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CXR48_RS12995 faf43944c468d461693fe45eaeb574f0 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 4.8E-71 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CXR48_RS12995 faf43944c468d461693fe45eaeb574f0 195 SUPERFAMILY SSF52540 16 193 3.05E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CXR48_RS14550 60a1ccfbc6747a5a06a0b8c350a880ba 84 Pfam PF11458 Membrane-integrating protein Mistic 1 81 4.0E-43 T 29-03-2018 IPR021078 Membrane-integrating protein Mistic CXR48_RS14550 60a1ccfbc6747a5a06a0b8c350a880ba 84 Gene3D G3DSA:1.10.220.90 1 74 3.2E-38 T 29-03-2018 CXR48_RS11760 3996037f45a0700f5e3068206f164567 318 Pfam PF07136 Protein of unknown function (DUF1385) 57 301 9.8E-78 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 CXR48_RS11760 3996037f45a0700f5e3068206f164567 318 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 57 296 9.0E-123 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 CXR48_RS18645 e6e0dbc37a37f8e564adfeb9a9b80704 121 Gene3D G3DSA:3.20.70.20 2 121 8.5E-4 T 29-03-2018 CXR48_RS18485 2f30519b99dbe0386cb4268c5bffeaed 416 Pfam PF11700 Vacuole effluxer Atg22 like 7 414 5.5E-57 T 29-03-2018 IPR024671 Autophagy-related protein 22-like CXR48_RS18485 2f30519b99dbe0386cb4268c5bffeaed 416 Gene3D G3DSA:1.20.1250.20 223 416 7.4E-24 T 29-03-2018 CXR48_RS18485 2f30519b99dbe0386cb4268c5bffeaed 416 Gene3D G3DSA:1.20.1250.20 12 215 1.9E-13 T 29-03-2018 CXR48_RS18485 2f30519b99dbe0386cb4268c5bffeaed 416 SUPERFAMILY SSF103473 17 413 1.27E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS06815 123a56a9c172a26dae7355784e2e420d 164 Pfam PF14489 QueF-like protein 61 139 1.2E-35 T 29-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CXR48_RS06815 123a56a9c172a26dae7355784e2e420d 164 PIRSF PIRSF027377 8 146 1.4E-61 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CXR48_RS06815 123a56a9c172a26dae7355784e2e420d 164 SUPERFAMILY SSF55620 26 135 2.74E-29 T 29-03-2018 CXR48_RS06815 123a56a9c172a26dae7355784e2e420d 164 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 27 137 5.4E-55 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CXR48_RS06815 123a56a9c172a26dae7355784e2e420d 164 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 164 72.294 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CXR48_RS06815 123a56a9c172a26dae7355784e2e420d 164 Gene3D G3DSA:3.30.1130.10 20 164 5.0E-43 T 29-03-2018 CXR48_RS11410 14fa2380de637b75e60428ce5425ea31 107 Pfam PF06942 GlpM protein 7 98 9.9E-9 T 29-03-2018 IPR009707 Membrane protein GlpM/YdgC CXR48_RS10535 100df4cf9f9c3f3513a6024276e27adc 144 Pfam PF14179 YppG-like protein 31 143 4.0E-21 T 29-03-2018 IPR025555 YppG-like protein CXR48_RS03950 b25dd9141963cfa748523c5ad4c4b8d4 93 Pfam PF14118 YfzA-like protein 4 87 4.3E-17 T 29-03-2018 IPR025627 YfzA-like protein CXR48_RS12990 28da6fd6168f9d2c863144baf2405600 163 ProDom PD104119 YSXD OB2071 ORFY 1 159 4.0E-47 T 29-03-2018 CXR48_RS11770 70c79fd3cd51b03f4ac418631dfa543b 291 Pfam PF01734 Patatin-like phospholipase 6 192 5.8E-30 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CXR48_RS11770 70c79fd3cd51b03f4ac418631dfa543b 291 Gene3D G3DSA:3.40.1090.10 6 266 3.2E-45 T 29-03-2018 CXR48_RS11770 70c79fd3cd51b03f4ac418631dfa543b 291 SUPERFAMILY SSF52151 6 288 8.37E-43 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 294 2.3E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 Gene3D G3DSA:3.50.50.60 164 334 5.4E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 Gene3D G3DSA:3.50.50.60 3 163 8.3E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 7.2E-19 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 7.2E-19 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 177 7.2E-19 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 7.2E-19 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 SUPERFAMILY SSF51905 4 316 1.22E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 4.5E-18 T 29-03-2018 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 4.5E-18 T 29-03-2018 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.5E-18 T 29-03-2018 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 4.5E-18 T 29-03-2018 CXR48_RS01715 f2b318e8f3c7057550dfe1a04958fe47 336 Hamap MF_01685 Ferredoxin--NADP reductase. 7 330 40.25 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CXR48_RS06490 875522b310d5a673c3fec575ce92283a 112 Pfam PF00893 Small Multidrug Resistance protein 1 89 3.0E-25 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CXR48_RS06490 875522b310d5a673c3fec575ce92283a 112 SUPERFAMILY SSF103481 6 99 2.62E-15 T 29-03-2018 CXR48_RS16865 a1d40a2db6d2e9b5d479e64b65e545be 376 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 374 1.3E-101 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CXR48_RS16865 a1d40a2db6d2e9b5d479e64b65e545be 376 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 204 372 1.3E-34 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 Gene3D G3DSA:3.50.50.60 1 381 3.3E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 Pfam PF01494 FAD binding domain 2 335 3.6E-92 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 271 286 7.6E-39 T 29-03-2018 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 322 7.6E-39 T 29-03-2018 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 7.6E-39 T 29-03-2018 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 7.6E-39 T 29-03-2018 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 338 7.6E-39 T 29-03-2018 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 302 7.6E-39 T 29-03-2018 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 SUPERFAMILY SSF51905 3 168 2.21E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS05240 490dca5c7c5722e281e735c7ab6e342c 493 SUPERFAMILY SSF51905 258 345 2.21E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CXR48_RS16950 d09f4a76521ed08e4bf9853a45de0e45 131 Pfam PF05025 RbsD / FucU transport protein family 1 130 3.1E-46 T 29-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CXR48_RS16950 d09f4a76521ed08e4bf9853a45de0e45 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 31.683 T 29-03-2018 IPR023064 D-ribose pyranase GO:0016872 CXR48_RS16950 d09f4a76521ed08e4bf9853a45de0e45 131 SUPERFAMILY SSF102546 1 131 2.22E-45 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CXR48_RS16950 d09f4a76521ed08e4bf9853a45de0e45 131 Gene3D G3DSA:3.40.1650.10 1 131 4.8E-38 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CXR48_RS11270 8776fd711fb0b1657e375667991f46e8 68 Pfam PF14164 YqzH-like protein 1 63 3.8E-27 T 29-03-2018 IPR025546 YqzH-like protein CXR48_RS02065 6c911bd16ecce1c4377cc8e458311c95 143 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3 141 4.4E-38 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS02065 6c911bd16ecce1c4377cc8e458311c95 143 Gene3D G3DSA:3.40.930.10 1 143 6.3E-37 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS02065 6c911bd16ecce1c4377cc8e458311c95 143 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CXR48_RS02065 6c911bd16ecce1c4377cc8e458311c95 143 SUPERFAMILY SSF55804 2 141 6.02E-42 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CXR48_RS15655 19aa982429b47153bb8d7e67281af039 370 Gene3D G3DSA:3.30.565.10 247 370 2.6E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15655 19aa982429b47153bb8d7e67281af039 370 SUPERFAMILY SSF55874 257 368 1.58E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CXR48_RS15655 19aa982429b47153bb8d7e67281af039 370 Pfam PF07730 Histidine kinase 180 246 8.5E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CXR48_RS08790 874ac2dd24f7645e1205e047778a806d 137 ProDom PD015812 YOPD YWLA YOAG 11 130 2.0E-41 T 29-03-2018 IPR031374 Uncharacterised protein family UPF0715 CXR48_RS08790 874ac2dd24f7645e1205e047778a806d 137 Pfam PF17094 Uncharacterised protein family (UPF0715) 11 129 2.1E-39 T 29-03-2018 IPR031374 Uncharacterised protein family UPF0715 CXR48_RS01230 84ed18ce4bb71add56a6e3dc687e55e4 158 Pfam PF16219 Domain of unknown function (DUF4879) 30 148 1.6E-17 T 29-03-2018 IPR032624 Protein of unknown function DUF4879 CXR48_RS04910 6925e58dd10f7bd2bbddb498c8535279 255 Gene3D G3DSA:3.90.226.10 1 197 1.2E-50 T 29-03-2018 CXR48_RS04910 6925e58dd10f7bd2bbddb498c8535279 255 SUPERFAMILY SSF52096 1 254 9.21E-66 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CXR48_RS04910 6925e58dd10f7bd2bbddb498c8535279 255 Gene3D G3DSA:1.10.12.10 198 255 1.3E-13 T 29-03-2018 IPR014748 Crontonase, C-terminal CXR48_RS04910 6925e58dd10f7bd2bbddb498c8535279 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 254 1.4E-43 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CXR48_RS19140 a33f2be88fd76273c98ee78103b10da1 311 Pfam PF09991 Predicted membrane protein (DUF2232) 16 300 7.4E-74 T 29-03-2018 IPR018710 Protein of unknown function DUF2232 CXR48_RS08100 653478ced60df9808ec86aee85868c28 147 Pfam PF02050 Flagellar FliJ protein 19 142 2.6E-18 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CXR48_RS08100 653478ced60df9808ec86aee85868c28 147 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 4 143 3.2E-37 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CXR48_RS19285 e421dad9fc52e03c0fb828b97d114fd0 237 Gene3D G3DSA:3.40.50.150 16 236 3.0E-5 T 29-03-2018 CXR48_RS16935 4699190b0347e650fbee3e32e61ff24c 377 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 206 374 1.7E-20 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CXR48_RS16935 4699190b0347e650fbee3e32e61ff24c 377 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 376 1.6E-68 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CXR48_RS01750 4b95332e12bbecba673b4e7247e0a564 106 Pfam PF10925 Protein of unknown function (DUF2680) 34 90 2.4E-25 T 29-03-2018 IPR024485 Protein of unknown function DUF2680 CXR48_RS01750 4b95332e12bbecba673b4e7247e0a564 106 ProDom PD673109 PRECURSOR SIGNAL YCKD ORF4 DOMAIN 1 105 2.0E-53 T 29-03-2018 IPR024485 Protein of unknown function DUF2680 CXR48_RS07005 fb1b6b2043f2bb7310606c3fce4de7e7 297 SUPERFAMILY SSF110296 8 187 7.32E-17 T 29-03-2018 CXR48_RS07005 fb1b6b2043f2bb7310606c3fce4de7e7 297 Gene3D G3DSA:2.130.10.10 11 275 1.8E-14 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CXR48_RS13845 936bcf8d91b899fc34de5c89f177a03a 148 Pfam PF11071 Nucleoside 2-deoxyribosyltransferase YtoQ 6 145 3.5E-64 T 29-03-2018 IPR019884 YtoQ family protein CXR48_RS13845 936bcf8d91b899fc34de5c89f177a03a 148 Gene3D G3DSA:3.40.50.450 1 147 1.9E-27 T 29-03-2018 CXR48_RS13845 936bcf8d91b899fc34de5c89f177a03a 148 SUPERFAMILY SSF52309 3 117 1.22E-5 T 29-03-2018 CXR48_RS13845 936bcf8d91b899fc34de5c89f177a03a 148 TIGRFAM TIGR03646 YtoQ_fam: YtoQ family protein 3 146 1.9E-69 T 29-03-2018 IPR019884 YtoQ family protein CXR48_RS05805 ea36a15d8f6d29da133be5d3fb0c6b1f 55 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 31 54 4.5E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS05805 ea36a15d8f6d29da133be5d3fb0c6b1f 55 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 29 53 3.8E-13 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS18665 897ac004099d87469252f7f7156f81be 622 PIRSF PIRSF018968 1 622 5.7E-134 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CXR48_RS18665 897ac004099d87469252f7f7156f81be 622 Pfam PF02687 FtsX-like permease family 85 175 1.4E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CXR48_RS04895 e2853f0505152301ff2a9597c5cc6cc1 404 Gene3D G3DSA:1.20.91.10 234 311 8.7E-7 T 29-03-2018 CXR48_RS04895 e2853f0505152301ff2a9597c5cc6cc1 404 Pfam PF00999 Sodium/hydrogen exchanger family 12 378 3.6E-60 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CXR48_RS19370 cbe6f98b5b6d25e03709cec6f8261964 68 Pfam PF06107 Bacterial protein of unknown function (DUF951) 7 59 2.2E-31 T 29-03-2018 IPR009296 Protein of unknown function DUF951 CXR48_RS19370 cbe6f98b5b6d25e03709cec6f8261964 68 PIRSF PIRSF037263 1 66 7.2E-36 T 29-03-2018 IPR009296 Protein of unknown function DUF951 CXR48_RS13350 bbffcd1d794d770d86b5174545fc50d1 146 Pfam PF03788 LrgA family 21 112 1.6E-23 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CXR48_RS12180 5087f93b8ea71ec1407ef99c03ad45d3 93 Pfam PF07873 YabP family 27 90 2.8E-19 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC CXR48_RS12180 5087f93b8ea71ec1407ef99c03ad45d3 93 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 8 91 2.5E-37 T 29-03-2018 IPR022477 Sporulation protein YqfC CXR48_RS14975 51c3be3d15bca7203c4fba532b8e3f56 175 Pfam PF01944 Stage II sporulation protein M 20 172 1.6E-22 T 29-03-2018 IPR002798 Stage II sporulation protein M-like CXR48_RS15560 001a1cb144c872665d669270b2ca4286 78 Pfam PF12645 Helix-turn-helix domain 13 54 8.6E-5 T 29-03-2018 IPR024760 Helix-turn-helix, conjugative transposon-like CXR48_RS03885 885dc2b4f47ef0cd60ac6d6b89f689ea 279 Pfam PF03631 Virulence factor BrkB 14 265 4.5E-71 T 29-03-2018 IPR017039 Virulence factor BrkB CXR48_RS03885 885dc2b4f47ef0cd60ac6d6b89f689ea 279 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 2 264 1.2E-82 T 29-03-2018 IPR017039 Virulence factor BrkB CXR48_RS03885 885dc2b4f47ef0cd60ac6d6b89f689ea 279 PIRSF PIRSF035875 1 277 4.0E-82 T 29-03-2018 IPR017039 Virulence factor BrkB CXR48_RS04685 d1bddd26b1f1c78430dd26baaca86bb8 468 Pfam PF04293 SpoVR like protein 5 406 4.7E-164 T 29-03-2018 IPR007390 Sporulation stage V, protein R CXR48_RS14810 82c6e20f367e012f7fae8f22197f169c 368 Pfam PF01594 AI-2E family transporter 18 348 3.2E-85 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CXR48_RS15880 a69ec6b45d68d716c0da514ce82ac416 244 TIGRFAM TIGR03732 lanti_perm_MutE: lantibiotic protection ABC transporter permease subunit, MutE/EpiE family 3 239 3.1E-82 T 29-03-2018 IPR021205 Lantibiotic ABC transporter permease subunit, SpaE/MutE CXR48_RS15535 75fd2ec69edfb0c8869557f373c2ecdc 314 SUPERFAMILY SSF53807 39 309 2.98E-66 T 29-03-2018 CXR48_RS15535 75fd2ec69edfb0c8869557f373c2ecdc 314 Gene3D G3DSA:3.40.50.1980 166 314 6.1E-39 T 29-03-2018 CXR48_RS15535 75fd2ec69edfb0c8869557f373c2ecdc 314 Pfam PF01497 Periplasmic binding protein 62 287 1.5E-40 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CXR48_RS15535 75fd2ec69edfb0c8869557f373c2ecdc 314 Gene3D G3DSA:3.40.50.1980 58 165 5.3E-35 T 29-03-2018 CXR48_RS10140 e852e695cc43ef0e5e84d3a154c825a6 85 Pfam PF10752 Protein of unknown function (DUF2533) 2 84 3.4E-39 T 29-03-2018 IPR019688 Protein of unknown function DUF2533 CXR48_RS11740 dd3f301d3b0885c05f50e43168bacd11 93 Pfam PF10942 Protein of unknown function (DUF2619) 19 87 1.4E-26 T 29-03-2018 IPR020390 Uncharacterised protein family YqhV CXR48_RS11740 dd3f301d3b0885c05f50e43168bacd11 93 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 12 91 7.0E-34 T 29-03-2018 IPR020390 Uncharacterised protein family YqhV CXR48_RS15375 403de612c911f39834cb37271507f209 110 Gene3D G3DSA:1.20.1260.10 1 80 4.4E-11 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS15375 403de612c911f39834cb37271507f209 110 Pfam PF07875 Coat F domain 22 83 3.1E-21 T 29-03-2018 IPR012851 Spore coat protein CotF-like CXR48_RS04725 542b65bd00b2999c1ef53c2544f91572 96 Pfam PF17453 Sigma-M inhibitor protein 1 96 3.8E-58 T 29-03-2018 IPR020496 Probable anti-sigma M factor YhdK CXR48_RS04725 542b65bd00b2999c1ef53c2544f91572 96 ProDom PD065873 YHDK TRANSCRIPTION ANTI-SIGMA-M REPRESSOR TRANSMEMBRANE MEMBRANE PROBABLE REGULATION FACTOR 1 96 4.0E-43 T 29-03-2018 IPR020496 Probable anti-sigma M factor YhdK CXR48_RS18360 ce9e8e61388440c4b528b8ee70e0545e 328 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 315 1.6E-126 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CXR48_RS18360 ce9e8e61388440c4b528b8ee70e0545e 328 Gene3D G3DSA:3.60.60.10 2 328 2.6E-96 T 29-03-2018 CXR48_RS18360 ce9e8e61388440c4b528b8ee70e0545e 328 SUPERFAMILY SSF56235 2 327 5.4E-114 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CXR48_RS11550 89bdeb256ae8692c68e0171d22498b9b 80 Pfam PF11118 Protein of unknown function (DUF2627) 2 77 1.9E-33 T 29-03-2018 IPR020138 Uncharacterised protein family YqzF CXR48_RS11550 89bdeb256ae8692c68e0171d22498b9b 80 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 1 77 1.0E-17 T 29-03-2018 IPR020138 Uncharacterised protein family YqzF CXR48_RS12555 b377bccfa08d4144598723a3a428a9b1 67 Pfam PF10750 Protein of unknown function (DUF2536) 1 65 5.8E-33 T 29-03-2018 IPR019686 Protein of unknown function DUF2536 CXR48_RS12210 b21f9821320b63c70e331f116b67bde9 308 Pfam PF02690 Na+/Pi-cotransporter 14 146 1.2E-30 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CXR48_RS12210 b21f9821320b63c70e331f116b67bde9 308 Pfam PF02690 Na+/Pi-cotransporter 160 282 6.0E-18 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CXR48_RS12210 b21f9821320b63c70e331f116b67bde9 308 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 2 307 7.9E-121 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CXR48_RS17735 396d5880a215314e2f352bb76ec19816 219 Pfam PF02163 Peptidase family M50 123 186 1.2E-8 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CXR48_RS16205 78b132c04501c0077211208256986932 235 Gene3D G3DSA:3.30.1890.10 38 151 2.5E-11 T 29-03-2018 CXR48_RS16205 78b132c04501c0077211208256986932 235 Pfam PF02706 Chain length determinant protein 4 93 5.9E-16 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CXR48_RS06095 e0eadf29fa555d0c11fc5b8f8838eb83 497 SMART SM00858 11 82 4.0E-13 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CXR48_RS06095 e0eadf29fa555d0c11fc5b8f8838eb83 497 Pfam PF08666 SAF domain 11 81 2.0E-11 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CXR48_RS06095 e0eadf29fa555d0c11fc5b8f8838eb83 497 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 107 496 1.8E-157 T 29-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CXR48_RS03790 88d0084efc72ae294acd161bb2a6301c 125 Pfam PF09350 Domain of unknown function (DUF1992) 8 70 2.1E-19 T 29-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain CXR48_RS07890 4d7a40970cbf310bfbae843b92fb45bb 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 4.6E-36 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CXR48_RS12000 e083901e7f2e6acb5e6a2506e4e043f3 300 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 4 286 5.9E-82 T 29-03-2018 IPR011862 Phosphate binding protein GO:0006810 CXR48_RS12000 e083901e7f2e6acb5e6a2506e4e043f3 300 Pfam PF12849 PBP superfamily domain 36 272 5.4E-42 T 29-03-2018 IPR024370 PBP domain CXR48_RS12000 e083901e7f2e6acb5e6a2506e4e043f3 300 Gene3D G3DSA:3.40.190.10 173 299 2.6E-20 T 29-03-2018 CXR48_RS12000 e083901e7f2e6acb5e6a2506e4e043f3 300 SUPERFAMILY SSF53850 46 294 1.31E-73 T 29-03-2018 CXR48_RS12000 e083901e7f2e6acb5e6a2506e4e043f3 300 Gene3D G3DSA:3.40.190.10 41 172 4.4E-34 T 29-03-2018 CXR48_RS18395 6a3b84b0004613538b2d80fbd3882ba9 447 Pfam PF03390 2-hydroxycarboxylate transporter family 31 439 1.1E-148 T 29-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 CXR48_RS18395 6a3b84b0004613538b2d80fbd3882ba9 447 PIRSF PIRSF005348 11 447 1.6E-163 T 29-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 CXR48_RS03835 6034ef0672746b51816b008a9ebe0c6a 379 Pfam PF07907 YibE/F-like protein 136 368 1.2E-69 T 29-03-2018 IPR012507 YibE/F-like CXR48_RS05030 b1ba3dfddc89a59e9c9a7b30a4dae485 395 PIRSF PIRSF005962 5 395 2.4E-133 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CXR48_RS05030 b1ba3dfddc89a59e9c9a7b30a4dae485 395 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 382 1.4E-116 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CXR48_RS05030 b1ba3dfddc89a59e9c9a7b30a4dae485 395 SUPERFAMILY SSF55031 188 306 2.22E-28 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS05030 b1ba3dfddc89a59e9c9a7b30a4dae485 395 Pfam PF07687 Peptidase dimerisation domain 192 284 9.7E-7 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CXR48_RS05030 b1ba3dfddc89a59e9c9a7b30a4dae485 395 Pfam PF01546 Peptidase family M20/M25/M40 79 388 2.0E-31 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CXR48_RS05030 b1ba3dfddc89a59e9c9a7b30a4dae485 395 Gene3D G3DSA:3.40.630.10 251 394 7.9E-26 T 29-03-2018 CXR48_RS05030 b1ba3dfddc89a59e9c9a7b30a4dae485 395 Gene3D G3DSA:3.40.630.10 2 249 1.3E-48 T 29-03-2018 CXR48_RS05030 b1ba3dfddc89a59e9c9a7b30a4dae485 395 SUPERFAMILY SSF53187 305 393 2.07E-85 T 29-03-2018 CXR48_RS05030 b1ba3dfddc89a59e9c9a7b30a4dae485 395 SUPERFAMILY SSF53187 9 204 2.07E-85 T 29-03-2018 CXR48_RS09055 e25c82a8b1a64244c8a02fe4512525ca 542 Pfam PF14158 YndJ-like protein 30 276 2.2E-72 T 29-03-2018 IPR025450 YndJ-like protein CXR48_RS04585 6d1d1d34e99bae9e2d7a6dc226cfa2e4 198 Gene3D G3DSA:2.40.260.10 25 198 4.5E-36 T 29-03-2018 IPR023365 Sortase domain CXR48_RS04585 6d1d1d34e99bae9e2d7a6dc226cfa2e4 198 Pfam PF04203 Sortase family 76 197 2.3E-25 T 29-03-2018 IPR005754 Sortase family CXR48_RS04585 6d1d1d34e99bae9e2d7a6dc226cfa2e4 198 SUPERFAMILY SSF63817 63 197 7.85E-33 T 29-03-2018 IPR023365 Sortase domain CXR48_RS04585 6d1d1d34e99bae9e2d7a6dc226cfa2e4 198 TIGRFAM TIGR01076 sortase_fam: sortase 74 195 1.0E-40 T 29-03-2018 IPR005754 Sortase family CXR48_RS05125 91f01b47369607a4b6cb243702581560 416 Gene3D G3DSA:3.30.2010.10 203 285 2.3E-19 T 29-03-2018 CXR48_RS05125 91f01b47369607a4b6cb243702581560 416 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 69 203 6.3E-16 T 29-03-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 CXR48_RS05125 91f01b47369607a4b6cb243702581560 416 Pfam PF01435 Peptidase family M48 207 415 1.8E-39 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CXR48_RS13725 caf2c7b0067df4e2e9195e3630b09970 250 Gene3D G3DSA:3.40.50.1110 41 250 2.5E-25 T 29-03-2018 CXR48_RS13725 caf2c7b0067df4e2e9195e3630b09970 250 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 52 236 1.8E-14 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS13725 caf2c7b0067df4e2e9195e3630b09970 250 SUPERFAMILY SSF52266 43 242 2.29E-39 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS13215 b622fcd93fc70eedbd2e690ba37bd794 85 Pfam PF05164 Cell division protein ZapA 10 82 8.4E-16 T 29-03-2018 IPR007838 Cell division protein ZapA-like CXR48_RS13215 b622fcd93fc70eedbd2e690ba37bd794 85 SUPERFAMILY SSF102829 10 84 4.18E-20 T 29-03-2018 IPR007838 Cell division protein ZapA-like CXR48_RS19080 bd7f5e1ba5252c1f0de57af6ba6e787b 65 ProDom PD054650 YYCD 1 65 8.0E-27 T 29-03-2018 IPR020086 Uncharacterised protein family YycD CXR48_RS19080 bd7f5e1ba5252c1f0de57af6ba6e787b 65 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 4 65 5.8E-15 T 29-03-2018 IPR018691 Protein of unknown function DUF2188 CXR48_RS11860 126b5a51c3fb1fa3dde7b0fdb008300b 104 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CXR48_RS11860 126b5a51c3fb1fa3dde7b0fdb008300b 104 ProDom PD073895 COMPETENCE COMGE LATE MACHINERY MEMBRANE OPERON DNA THE METHYLATION PART 1 104 2.0E-22 T 29-03-2018 IPR020488 Competence operon G, ComGE CXR48_RS15595 58f03b9f9bb9431b0c38d4fcdb8d708c 354 Gene3D G3DSA:1.10.3470.10 24 354 5.8E-67 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS15595 58f03b9f9bb9431b0c38d4fcdb8d708c 354 Pfam PF01032 FecCD transport family 40 349 7.7E-91 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CXR48_RS15595 58f03b9f9bb9431b0c38d4fcdb8d708c 354 SUPERFAMILY SSF81345 22 349 7.19E-84 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CXR48_RS06345 443ef4d0113eefa8443da9a6455dfe5f 123 Pfam PF09636 XkdW protein 64 123 2.5E-9 T 29-03-2018 IPR019094 Bacteriophage SP-beta, YorD CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 Gene3D G3DSA:3.40.50.1980 197 317 1.0E-35 T 29-03-2018 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 314 1.3E-79 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 SUPERFAMILY SSF53807 16 316 3.34E-87 T 29-03-2018 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00690 Adhesin family signature 81 98 4.1E-16 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00690 Adhesin family signature 68 81 4.1E-16 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00690 Adhesin family signature 255 273 4.1E-16 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00690 Adhesin family signature 37 55 4.1E-16 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00690 Adhesin family signature 202 223 4.1E-16 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00691 Adhesin B signature 202 219 8.1E-17 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00691 Adhesin B signature 37 58 8.1E-17 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00691 Adhesin B signature 62 80 8.1E-17 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00691 Adhesin B signature 146 165 8.1E-17 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00691 Adhesin B signature 81 100 8.1E-17 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 PRINTS PR00691 Adhesin B signature 295 313 8.1E-17 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CXR48_RS01525 356c1aaeb2b431cc4ea271b8029ae83f 319 Gene3D G3DSA:3.40.50.1980 37 196 1.5E-58 T 29-03-2018 CXR48_RS12420 57a78bcac0f62705579a9295da90066d 173 PRINTS PR01754 Streptothricin acetyltransferase signature 138 154 3.3E-23 T 29-03-2018 IPR008125 Streptothricin acetyltransferase CXR48_RS12420 57a78bcac0f62705579a9295da90066d 173 PRINTS PR01754 Streptothricin acetyltransferase signature 93 108 3.3E-23 T 29-03-2018 IPR008125 Streptothricin acetyltransferase CXR48_RS12420 57a78bcac0f62705579a9295da90066d 173 PRINTS PR01754 Streptothricin acetyltransferase signature 117 132 3.3E-23 T 29-03-2018 IPR008125 Streptothricin acetyltransferase CXR48_RS12420 57a78bcac0f62705579a9295da90066d 173 PRINTS PR01754 Streptothricin acetyltransferase signature 160 173 3.3E-23 T 29-03-2018 IPR008125 Streptothricin acetyltransferase CXR48_RS12420 57a78bcac0f62705579a9295da90066d 173 Pfam PF00583 Acetyltransferase (GNAT) family 47 146 1.7E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CXR48_RS12420 57a78bcac0f62705579a9295da90066d 173 SUPERFAMILY SSF55729 32 156 2.16E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CXR48_RS12420 57a78bcac0f62705579a9295da90066d 173 Gene3D G3DSA:3.40.630.30 3 168 9.9E-21 T 29-03-2018 CXR48_RS14685 328132c6f588ed575ebb76d8d0a5e546 357 Gene3D G3DSA:3.40.50.2300 35 155 9.3E-42 T 29-03-2018 CXR48_RS14685 328132c6f588ed575ebb76d8d0a5e546 357 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 38 347 4.0E-98 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CXR48_RS14685 328132c6f588ed575ebb76d8d0a5e546 357 SUPERFAMILY SSF53822 49 301 1.21E-12 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CXR48_RS14685 328132c6f588ed575ebb76d8d0a5e546 357 Gene3D G3DSA:3.40.50.2300 156 353 6.6E-43 T 29-03-2018 CXR48_RS03805 ae9d7882e26cd3c1c4dde11834611c77 86 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 1.7E-19 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CXR48_RS02095 d0872fd8419ddefc1caac5d764c7d6ba 404 Pfam PF01566 Natural resistance-associated macrophage protein 51 371 6.0E-20 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CXR48_RS09420 182688822898fcc0b367007e355fe070 110 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 109 5.5E-47 T 29-03-2018 IPR008231 Probable chaperone CsaA CXR48_RS09420 182688822898fcc0b367007e355fe070 110 Gene3D G3DSA:2.40.50.140 1 110 8.2E-19 T 29-03-2018 CXR48_RS09420 182688822898fcc0b367007e355fe070 110 SUPERFAMILY SSF50249 4 109 5.88E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CXR48_RS09420 182688822898fcc0b367007e355fe070 110 Pfam PF01588 Putative tRNA binding domain 12 108 7.7E-17 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CXR48_RS12480 dfbe2ec3dea0d8aa35f1ca3c5628d6ba 402 Pfam PF07690 Major Facilitator Superfamily 18 329 7.1E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CXR48_RS12480 dfbe2ec3dea0d8aa35f1ca3c5628d6ba 402 Gene3D G3DSA:1.20.1250.20 7 204 2.2E-33 T 29-03-2018 CXR48_RS12480 dfbe2ec3dea0d8aa35f1ca3c5628d6ba 402 SUPERFAMILY SSF103473 6 396 2.09E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CXR48_RS12480 dfbe2ec3dea0d8aa35f1ca3c5628d6ba 402 Gene3D G3DSA:1.20.1250.20 205 400 3.1E-15 T 29-03-2018 CXR48_RS10000 55cd9b782e2b54cee30fe364204acdce 251 Gene3D G3DSA:3.40.50.1110 33 247 3.3E-33 T 29-03-2018 CXR48_RS10000 55cd9b782e2b54cee30fe364204acdce 251 SUPERFAMILY SSF52266 34 245 3.66E-35 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS10000 55cd9b782e2b54cee30fe364204acdce 251 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 41 234 3.1E-25 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CXR48_RS00290 4ee69a25a4fe2db0549cc1271924d4f4 62 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 54 2.7E-7 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CXR48_RS00290 4ee69a25a4fe2db0549cc1271924d4f4 62 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CXR48_RS05325 3f034ea8b39a7387015abeb8134053d4 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 3.5E-31 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CXR48_RS09645 01a0c7a6e8af4e21e313acccf6b58145 154 SUPERFAMILY SSF49764 65 152 2.93E-8 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS09645 01a0c7a6e8af4e21e313acccf6b58145 154 Gene3D G3DSA:2.60.40.790 51 149 5.0E-6 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS17385 c8dad98c998b06d02d3b3c8d42b6e7a0 76 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 10 76 2.0E-22 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 CXR48_RS17385 c8dad98c998b06d02d3b3c8d42b6e7a0 76 Pfam PF06612 Protein of unknown function (DUF1146) 16 63 7.8E-22 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 CXR48_RS08815 4077afdb3fa96b3d471d62e617550f7c 206 Gene3D G3DSA:2.70.50.50 31 205 4.7E-51 T 29-03-2018 CXR48_RS08815 4077afdb3fa96b3d471d62e617550f7c 206 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 28 202 9.1E-37 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CXR48_RS08815 4077afdb3fa96b3d471d62e617550f7c 206 SUPERFAMILY SSF81296 28 204 7.14E-53 T 29-03-2018 IPR014756 Immunoglobulin E-set CXR48_RS06610 4564ed15aae9c106a61794653618aef4 110 Gene3D G3DSA:1.10.1660.10 3 106 4.1E-21 T 29-03-2018 CXR48_RS06610 4564ed15aae9c106a61794653618aef4 110 Pfam PF13411 MerR HTH family regulatory protein 15 76 5.0E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS06610 4564ed15aae9c106a61794653618aef4 110 SUPERFAMILY SSF46955 15 103 1.97E-18 T 29-03-2018 IPR009061 Putative DNA-binding domain CXR48_RS06610 4564ed15aae9c106a61794653618aef4 110 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 26 8.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS06610 4564ed15aae9c106a61794653618aef4 110 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 49 69 8.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS06610 4564ed15aae9c106a61794653618aef4 110 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 26 39 8.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS06610 4564ed15aae9c106a61794653618aef4 110 SMART SM00422 14 82 4.1E-24 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CXR48_RS10895 e3aa733db5275b096c2fa1658e302fce 194 PIRSF PIRSF029008 1 194 3.2E-63 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CXR48_RS10895 e3aa733db5275b096c2fa1658e302fce 194 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 89 1.3E-25 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CXR48_RS10895 e3aa733db5275b096c2fa1658e302fce 194 Pfam PF05389 Negative regulator of genetic competence (MecA) 101 189 3.7E-13 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CXR48_RS10895 e3aa733db5275b096c2fa1658e302fce 194 Hamap MF_01124 Adapter protein MecA [mecA]. 1 193 24.605 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CXR48_RS06825 670598b69059b4ed723511cfe64837c1 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 2 57 4.1E-29 T 29-03-2018 IPR018690 Protein of unknown function DUF2187 CXR48_RS08590 b6e9b8d153961e774f2e33ed353581b7 144 Pfam PF14040 Deoxyribonuclease NucA/NucB 47 137 1.8E-11 T 29-03-2018 IPR029476 Deoxyribonuclease NucA/NucB CXR48_RS03135 ce7c88145bf801a4217fa772f9fda923 105 Pfam PF14154 Domain of unknown function (DUF4306) 7 89 9.7E-28 T 29-03-2018 IPR025440 Protein of unknown function DUF4306 CXR48_RS04620 71a8bd1552efe233afa647cf12b143d9 191 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 8 180 3.8E-64 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CXR48_RS04620 71a8bd1552efe233afa647cf12b143d9 191 PIRSF PIRSF016897 1 186 3.3E-68 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CXR48_RS04620 71a8bd1552efe233afa647cf12b143d9 191 Gene3D G3DSA:3.20.20.400 1 181 2.9E-70 T 29-03-2018 CXR48_RS04620 71a8bd1552efe233afa647cf12b143d9 191 SUPERFAMILY SSF110391 8 180 1.96E-61 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CXR48_RS14050 a55d29ba6220e0e130f44b552c4e2336 327 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 171 183 3.0E-35 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14050 a55d29ba6220e0e130f44b552c4e2336 327 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 94 108 3.0E-35 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14050 a55d29ba6220e0e130f44b552c4e2336 327 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 154 168 3.0E-35 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14050 a55d29ba6220e0e130f44b552c4e2336 327 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 259 278 3.0E-35 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS14050 a55d29ba6220e0e130f44b552c4e2336 327 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 239 253 3.0E-35 T 29-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CXR48_RS01270 6bb6a283c8e1a011411e0447ccaaff00 80 Pfam PF10852 Protein of unknown function (DUF2651) 8 77 3.6E-20 T 29-03-2018 IPR020258 Uncharacterised protein family YbeF CXR48_RS01270 6bb6a283c8e1a011411e0447ccaaff00 80 ProDom PD060054 MEMBRANE SPANNING TRANSMEMBRANE YBEF 2 73 5.0E-17 T 29-03-2018 IPR020258 Uncharacterised protein family YbeF CXR48_RS15765 df0029eff5c7ff18c3a1e3bfd0eeaec3 95 Gene3D G3DSA:3.40.30.10 1 88 2.2E-14 T 29-03-2018 CXR48_RS15765 df0029eff5c7ff18c3a1e3bfd0eeaec3 95 Pfam PF00462 Glutaredoxin 7 62 9.7E-15 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CXR48_RS15765 df0029eff5c7ff18c3a1e3bfd0eeaec3 95 SUPERFAMILY SSF52833 5 64 8.66E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS03870 c7166ba0f81c9e9fbc6f32fbe8edc4ae 71 Pfam PF06569 Protein of unknown function (DUF1128) 3 71 1.7E-31 T 29-03-2018 IPR009507 Protein of unknown function UPF0435 CXR48_RS03870 c7166ba0f81c9e9fbc6f32fbe8edc4ae 71 Hamap MF_00829 UPF0435 protein . 4 71 19.983 T 29-03-2018 IPR009507 Protein of unknown function UPF0435 CXR48_RS09505 70c98d273b73e9d7025613a8c1aacb67 126 Pfam PF10737 Spore germination protein GerPC 51 113 9.9E-7 T 29-03-2018 IPR019673 Spore germination protein GerPC CXR48_RS06675 571f2067df78a62f5fc60ff1b1647cdf 233 Pfam PF08876 Domain of unknown function (DUF1836) 62 158 4.9E-18 T 29-03-2018 IPR014975 Protein of unknown function DUF1836 CXR48_RS05770 16f4ab0d1ceaf2ec323c00ea6a53b7cc 147 Pfam PF10612 Spore coat protein Z 3 138 2.4E-30 T 29-03-2018 IPR019593 Spore coat protein Z/Y CXR48_RS12785 3448c5e71c6daf3850a25e58f4b0168c 66 Pfam PF11146 Protein of unknown function (DUF2905) 6 62 1.1E-22 T 29-03-2018 IPR021320 Protein of unknown function DUF2905 CXR48_RS01745 aa8bf5d113381398f45842ab87e9e680 144 Pfam PF06271 RDD family 6 128 1.1E-17 T 29-03-2018 IPR010432 RDD CXR48_RS08705 5793ecff1d0f1c6c53634ddcabdd1f36 421 Gene3D G3DSA:3.40.640.10 58 272 1.2E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CXR48_RS08705 5793ecff1d0f1c6c53634ddcabdd1f36 421 Pfam PF06838 Methionine gamma-lyase 12 415 1.8E-210 T 29-03-2018 IPR009651 Putative methionine gamma-lyase CXR48_RS08705 5793ecff1d0f1c6c53634ddcabdd1f36 421 SUPERFAMILY SSF53383 55 399 1.44E-50 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CXR48_RS12425 f3853e18056928bdd583d435c654509d 166 Pfam PF05163 DinB family 1 159 3.4E-41 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CXR48_RS12425 f3853e18056928bdd583d435c654509d 166 Gene3D G3DSA:1.20.120.450 1 150 2.2E-23 T 29-03-2018 CXR48_RS12425 f3853e18056928bdd583d435c654509d 166 SUPERFAMILY SSF109854 8 152 5.49E-33 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CXR48_RS02590 c72499ad1b04b12fb508f238918d2daf 86 Pfam PF02583 Metal-sensitive transcriptional repressor 5 82 3.9E-25 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CXR48_RS02295 2a423e1ab4f97abb6d55e72f42138bae 123 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 24 41 2.2E-6 T 29-03-2018 IPR019626 Stress-induced protein, KGG, repeat CXR48_RS02295 2a423e1ab4f97abb6d55e72f42138bae 123 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 44 61 2.6E-6 T 29-03-2018 IPR019626 Stress-induced protein, KGG, repeat CXR48_RS02295 2a423e1ab4f97abb6d55e72f42138bae 123 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 104 118 2.3E-4 T 29-03-2018 IPR019626 Stress-induced protein, KGG, repeat CXR48_RS02295 2a423e1ab4f97abb6d55e72f42138bae 123 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 64 81 2.6E-6 T 29-03-2018 IPR019626 Stress-induced protein, KGG, repeat CXR48_RS02295 2a423e1ab4f97abb6d55e72f42138bae 123 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 84 101 2.2E-6 T 29-03-2018 IPR019626 Stress-induced protein, KGG, repeat CXR48_RS17045 d0cdf00fd06c4009c73ba3216c9790de 178 Pfam PF02417 Chromate transporter 6 170 1.4E-35 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CXR48_RS01425 ff3bb7478ffba9c531b5133c9848b23f 142 Pfam PF07486 Cell Wall Hydrolase 24 128 3.9E-19 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CXR48_RS17005 909e47ac1ed56515b677ceb20873f152 297 Gene3D G3DSA:2.130.10.10 14 288 4.0E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CXR48_RS17005 909e47ac1ed56515b677ceb20873f152 297 ProDom PD210561 YWRJ 15 140 0.007 T 29-03-2018 IPR020173 Uncharacterised protein family YwrJ CXR48_RS06375 a683e066db0de79cb910ffe75f2da37f 56 Pfam PF14185 Antitoxin SpoIISB, type II toxin-antitoxin system 1 56 2.3E-30 T 29-03-2018 IPR025897 Antitoxin SpoIISB CXR48_RS18900 4de805281e495ebeffb5d8ee40332c59 56 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 5 53 9.9E-21 T 29-03-2018 IPR025626 YyzF-like protein CXR48_RS18900 4de805281e495ebeffb5d8ee40332c59 56 Pfam PF14116 YyzF-like protein 7 54 1.0E-18 T 29-03-2018 IPR025626 YyzF-like protein CXR48_RS11755 75f5f477704a36568a4b9bf701c7d528 176 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 21 163 2.0E-56 T 29-03-2018 IPR024563 Uncharacterised protein family YqhR CXR48_RS11755 75f5f477704a36568a4b9bf701c7d528 176 Pfam PF11085 Conserved membrane protein YqhR 8 171 3.0E-72 T 29-03-2018 IPR024563 Uncharacterised protein family YqhR CXR48_RS03325 2e1c56b8ac736db2ee2c61f831bc081d 76 Pfam PF11127 Protein of unknown function (DUF2892) 1 63 1.3E-11 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 CXR48_RS18435 ebfbb4e435a50bd531490f5f2ab5adf4 158 Pfam PF04525 LURP-one-related 5 148 2.7E-23 T 29-03-2018 IPR007612 LURP1-related protein domain CXR48_RS18435 ebfbb4e435a50bd531490f5f2ab5adf4 158 SUPERFAMILY SSF54518 2 152 6.02E-33 T 29-03-2018 IPR025659 Tubby C-terminal-like domain CXR48_RS05540 0ebcb4c8360806cd30f6807db9fb37b4 188 ProDom PD032558 YJAV MED CDS GENES ARGF 1 117 3.0E-34 T 29-03-2018 CXR48_RS05540 0ebcb4c8360806cd30f6807db9fb37b4 188 Gene3D G3DSA:3.40.50.720 1 180 3.3E-5 T 29-03-2018 CXR48_RS16060 35c66e36d1e92812b40e00ab4a926647 135 Gene3D G3DSA:2.60.120.260 15 133 6.6E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS11105 4c6c219790b2b64c1069d782c9da9c14 150 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 24 141 7.0E-42 T 29-03-2018 IPR005562 SpoVA CXR48_RS11105 4c6c219790b2b64c1069d782c9da9c14 150 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 7 143 5.1E-66 T 29-03-2018 IPR014203 Sporulation stage V, protein AC CXR48_RS02125 24c866558a6be89f933a25fffdc3935a 81 Pfam PF13129 Protein of unknown function (DUF3953) 34 73 3.9E-13 T 29-03-2018 IPR025018 Protein of unknown function DUF3953 CXR48_RS05230 b0ccd7f48ed6c2e138897bd690b5c100 208 Pfam PF09335 SNARE associated Golgi protein 41 159 4.5E-18 T 29-03-2018 IPR032816 SNARE associated Golgi protein CXR48_RS17805 b360c0092fd3455482ca8d1605cc85fe 325 Pfam PF03601 Conserved hypothetical protein 698 5 305 2.6E-78 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CXR48_RS04150 7d0dc4204a597d1da6fc31f105a06ac3 111 Pfam PF13630 SdpI/YhfL protein family 24 95 5.3E-15 T 29-03-2018 IPR025962 SdpI/YhfL protein family CXR48_RS04210 37c14b7c31a38c1ab186d05f518ec141 354 Pfam PF06081 Aromatic acid exporter family member 1 1 142 2.3E-42 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CXR48_RS03105 94732be96bffaf2904ad0dc5ed466834 283 Pfam PF13020 Domain of unknown function (DUF3883) 157 244 6.7E-11 T 29-03-2018 IPR024975 Domain of unknown function DUF3883 CXR48_RS16550 c11b6ce4d2624089b8afbaff14f8a9f9 78 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 4 75 9.8E-30 T 29-03-2018 IPR019242 Protein of unknown function DUF2198 CXR48_RS15035 548182dfd8b2c94b34bc89c83c05d5db 78 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 1 77 3.0E-34 T 29-03-2018 CXR48_RS15035 548182dfd8b2c94b34bc89c83c05d5db 78 Pfam PF07293 Protein of unknown function (DUF1450) 1 75 4.1E-36 T 29-03-2018 IPR009910 Protein of unknown function DUF1450 CXR48_RS15035 548182dfd8b2c94b34bc89c83c05d5db 78 Hamap MF_01542 UPF0349 protein . 1 77 29.641 T 29-03-2018 IPR022916 Protein of unknown function UPF0349 CXR48_RS07880 1aa3f7358ca691b9e2fe41b2eaf6e1f8 26 Pfam PF08183 Stage V sporulation protein family 1 25 4.0E-18 T 29-03-2018 IPR012609 Sporulation stage V, protein M CXR48_RS09665 3c621f863afa1fe94c086d7ac4162812 113 SUPERFAMILY SSF46785 6 105 3.2E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09665 3c621f863afa1fe94c086d7ac4162812 113 Gene3D G3DSA:1.10.10.10 13 104 3.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CXR48_RS09665 3c621f863afa1fe94c086d7ac4162812 113 Pfam PF01638 HxlR-like helix-turn-helix 15 103 8.3E-36 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CXR48_RS13275 8ed97a4ed5e33be4b7e80ce19ed2907a 313 Gene3D G3DSA:1.10.3720.10 76 307 9.3E-44 T 29-03-2018 CXR48_RS13275 8ed97a4ed5e33be4b7e80ce19ed2907a 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 300 2.1E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS13275 8ed97a4ed5e33be4b7e80ce19ed2907a 313 Gene3D G3DSA:1.20.58.370 21 61 3.0E-5 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CXR48_RS13275 8ed97a4ed5e33be4b7e80ce19ed2907a 313 SUPERFAMILY SSF161098 72 300 6.02E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CXR48_RS05295 b18df18ec6c19279d22894ea0be05a3e 97 Gene3D G3DSA:3.40.1800.10 1 61 1.6E-6 T 29-03-2018 CXR48_RS14700 7c10c304467e1da2eb9f1b79401c68bd 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 296 6.0E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CXR48_RS14700 7c10c304467e1da2eb9f1b79401c68bd 319 Gene3D G3DSA:1.10.3470.10 3 305 2.1E-43 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CXR48_RS09685 47e24b88470f1f68ce7afd303324c531 66 Pfam PF11755 Protein of unknown function (DUF3311) 9 62 1.1E-13 T 29-03-2018 IPR021741 Protein of unknown function DUF3311 CXR48_RS06265 1df64d127163a05a0d2b5c8a2d80e041 167 ProDom PD034535 XKDI PHAGE PHAGE-LIKE PBSX LIN1275 RELATED ELEMENT YQBI 1 162 5.0E-57 T 29-03-2018 CXR48_RS06265 1df64d127163a05a0d2b5c8a2d80e041 167 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 10 92 5.4E-8 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CXR48_RS08965 cccf965ad26accc3b9bd2b6af369ce99 138 SUPERFAMILY SSF54637 6 133 6.54E-39 T 29-03-2018 IPR029069 HotDog domain CXR48_RS08965 cccf965ad26accc3b9bd2b6af369ce99 138 Pfam PF03061 Thioesterase superfamily 18 102 3.2E-15 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CXR48_RS08965 cccf965ad26accc3b9bd2b6af369ce99 138 PIRSF PIRSF003230 1 136 2.2E-32 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CXR48_RS08965 cccf965ad26accc3b9bd2b6af369ce99 138 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 123 3.3E-42 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CXR48_RS08965 cccf965ad26accc3b9bd2b6af369ce99 138 Gene3D G3DSA:3.10.129.10 2 138 4.6E-36 T 29-03-2018 CXR48_RS00990 ba3dfc4ec738ead704346e3f12ed0ed4 477 SUPERFAMILY SSF52091 391 475 1.96E-14 T 29-03-2018 IPR002645 STAS domain CXR48_RS00990 ba3dfc4ec738ead704346e3f12ed0ed4 477 Pfam PF00916 Sulfate permease family 163 355 1.4E-31 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CXR48_RS00990 ba3dfc4ec738ead704346e3f12ed0ed4 477 Pfam PF00916 Sulfate permease family 15 143 2.4E-26 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CXR48_RS00990 ba3dfc4ec738ead704346e3f12ed0ed4 477 Gene3D G3DSA:3.30.750.24 388 477 2.5E-16 T 29-03-2018 IPR002645 STAS domain CXR48_RS00990 ba3dfc4ec738ead704346e3f12ed0ed4 477 ProSitePatterns PS01130 SLC26A transporters signature. 43 64 - T 29-03-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 CXR48_RS00990 ba3dfc4ec738ead704346e3f12ed0ed4 477 Pfam PF01740 STAS domain 394 475 2.3E-8 T 29-03-2018 IPR002645 STAS domain CXR48_RS11585 0a91f5dcb26afafa64cd34e79a565888 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 234 1.3E-50 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CXR48_RS11585 0a91f5dcb26afafa64cd34e79a565888 245 Gene3D G3DSA:3.20.20.190 1 244 1.4E-69 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CXR48_RS11585 0a91f5dcb26afafa64cd34e79a565888 245 SUPERFAMILY SSF51695 3 238 4.45E-71 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CXR48_RS01760 24d783d08e804050c2aa54e0b7af3475 132 ProDom PD081734 COMPETENCE J NIN DNA-ENTRY MEMBRANE INHIBITOR NUCLEASE 10 128 3.0E-63 T 29-03-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ CXR48_RS01760 24d783d08e804050c2aa54e0b7af3475 132 Pfam PF11033 Competence protein J (ComJ) 9 129 9.1E-45 T 29-03-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ CXR48_RS08090 6449288cd92e7c62b6c8e13898ebdc7d 251 TIGRFAM TIGR03825 FliH_bacil: flagellar assembly protein FliH 1 249 2.3E-82 T 29-03-2018 IPR022524 Flagellar assembly FliH, Bacilli CXR48_RS08090 6449288cd92e7c62b6c8e13898ebdc7d 251 Pfam PF02108 Flagellar assembly protein FliH 111 237 1.7E-17 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CXR48_RS01600 8c083888aa20e3d2b6b77c79cc4424ff 477 Pfam PF03606 C4-dicarboxylate anaerobic carrier 18 470 5.4E-79 T 29-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CXR48_RS07395 6b0cb0a14aff3614089c5362d530ad1a 93 Hamap MF_01560 UPF0358 protein . 3 93 26.816 T 29-03-2018 IPR009983 Uncharacterised protein family UPF0358 CXR48_RS07395 6b0cb0a14aff3614089c5362d530ad1a 93 SUPERFAMILY SSF140404 7 84 7.59E-37 T 29-03-2018 IPR009983 Uncharacterised protein family UPF0358 CXR48_RS07395 6b0cb0a14aff3614089c5362d530ad1a 93 Gene3D G3DSA:1.10.287.750 8 90 4.7E-41 T 29-03-2018 CXR48_RS07395 6b0cb0a14aff3614089c5362d530ad1a 93 Pfam PF07408 Protein of unknown function (DUF1507) 9 90 4.2E-41 T 29-03-2018 IPR009983 Uncharacterised protein family UPF0358 CXR48_RS03755 d5d0c20db7064853d75830e8cff963be 44 Pfam PF11121 Protein of unknown function (DUF2639) 2 39 5.6E-20 T 29-03-2018 IPR022580 Protein of unknown function DUF2639 CXR48_RS03755 d5d0c20db7064853d75830e8cff963be 44 ProDom PD049467 YFLJ 1 43 1.0E-14 T 29-03-2018 IPR022580 Protein of unknown function DUF2639 CXR48_RS14470 aff854e410b019343380e06845322463 276 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 275 18.131 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CXR48_RS14470 aff854e410b019343380e06845322463 276 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 268 3.0E-101 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CXR48_RS14470 aff854e410b019343380e06845322463 276 Pfam PF02673 Bacitracin resistance protein BacA 9 270 5.9E-84 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CXR48_RS10325 2e3fd85f5158d9bf608b85500d2ba40f 121 Pfam PF01844 HNH endonuclease 70 116 3.2E-9 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CXR48_RS10325 2e3fd85f5158d9bf608b85500d2ba40f 121 Gene3D G3DSA:3.40.1800.10 48 121 3.1E-8 T 29-03-2018 CXR48_RS10325 2e3fd85f5158d9bf608b85500d2ba40f 121 SMART SM00507 57 113 1.6E-5 T 29-03-2018 IPR003615 HNH nuclease CXR48_RS00025 f3254081f046bda83da09e619868b07c 81 Pfam PF04025 Domain of unknown function (DUF370) 3 72 2.0E-8 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CXR48_RS06835 60170e8c5a5f9a6a0cd2ca5af4d15f54 207 Pfam PF07486 Cell Wall Hydrolase 108 205 1.7E-26 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CXR48_RS16165 bb793db53620019496a007e5522e30a6 358 Pfam PF04230 Polysaccharide pyruvyl transferase 52 293 3.4E-31 T 29-03-2018 IPR007345 Polysaccharide pyruvyl transferase CXR48_RS04050 c87885e5c9cc294b39873d5e9db91b89 362 Pfam PF01757 Acyltransferase family 8 327 1.7E-18 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CXR48_RS11970 3e9dacd80c5c1afc31aceb98853e6ecb 117 Gene3D G3DSA:2.60.120.10 10 116 1.7E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CXR48_RS03595 9e268287c716eceec6c164b97fdd8673 312 SUPERFAMILY SSF53448 4 286 4.05E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS03595 9e268287c716eceec6c164b97fdd8673 312 Gene3D G3DSA:3.90.550.10 1 291 1.4E-13 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS09360 95ad23a04088ed1aa56673ccafeea74b 101 Gene3D G3DSA:1.20.5.320 32 93 0.0012 T 29-03-2018 CXR48_RS06260 828b6d21094d0dc612f99d96a549ff60 118 Pfam PF12206 Domain of unknown function (DUF3599) 1 115 1.9E-48 T 29-03-2018 IPR024556 Protein of unknown function DUF3599 CXR48_RS06260 828b6d21094d0dc612f99d96a549ff60 118 ProDom PD031312 YQBH LIN1274 PHAGE XKDH PHAGE-LIKE PBSX RELATED ELEMENT 1 118 6.0E-43 T 29-03-2018 IPR024556 Protein of unknown function DUF3599 CXR48_RS15500 cbe044eb338abea0f566bf48579f07a5 289 Pfam PF13349 Putative adhesin 48 288 8.2E-41 T 29-03-2018 IPR025164 Putative adhesin CXR48_RS16520 679b2962fd47b9cbaf9ea9f293b6aed4 64 Pfam PF04024 PspC domain 2 59 3.0E-19 T 29-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CXR48_RS04500 0572b3f1983da029a3d3f6b43fc5cb4a 177 Gene3D G3DSA:3.40.50.360 1 177 1.1E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS04500 0572b3f1983da029a3d3f6b43fc5cb4a 177 SUPERFAMILY SSF52218 1 169 7.73E-45 T 29-03-2018 IPR029039 Flavoprotein-like domain CXR48_RS04500 0572b3f1983da029a3d3f6b43fc5cb4a 177 Pfam PF03358 NADPH-dependent FMN reductase 43 121 2.6E-12 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CXR48_RS11950 74c8ff10d5b603fef592bbb160b2782f 454 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 451 1.2E-135 T 29-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CXR48_RS11950 74c8ff10d5b603fef592bbb160b2782f 454 Pfam PF03553 Na+/H+ antiporter family 159 451 1.4E-68 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CXR48_RS14760 60c0399e3bdb6bccd8cae296ba68388f 54 Pfam PF05952 Bacillus competence pheromone ComX 1 47 2.8E-16 T 29-03-2018 IPR009233 Competence pheromone ComX, Bacillus CXR48_RS02790 a8422b8578432e8985c4d7cc128b2c74 81 Gene3D G3DSA:1.20.1260.10 1 79 3.3E-7 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS18125 e863806f80caafcee1214e4d08842d3a 224 Pfam PF13712 Glycosyltransferase like family 8 218 1.6E-76 T 29-03-2018 CXR48_RS19165 bfa8be47362624216afe82190ec4a2f7 285 SUPERFAMILY SSF103481 33 139 3.4E-12 T 29-03-2018 CXR48_RS19165 bfa8be47362624216afe82190ec4a2f7 285 Pfam PF00892 EamA-like transporter family 1 136 1.4E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS19165 bfa8be47362624216afe82190ec4a2f7 285 Pfam PF00892 EamA-like transporter family 148 281 1.4E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CXR48_RS19165 bfa8be47362624216afe82190ec4a2f7 285 SUPERFAMILY SSF103481 190 283 1.57E-9 T 29-03-2018 CXR48_RS15875 ff36f6ae9875173b9301a973864c0e49 256 TIGRFAM TIGR03733 lanti_perm_MutG: lantibiotic protection ABC transporter permease subunit, MutG family 6 252 8.3E-74 T 29-03-2018 IPR022294 Lantibiotic protection ABC transporter permease subunit, MutG family CXR48_RS15875 ff36f6ae9875173b9301a973864c0e49 256 Pfam PF12730 ABC-2 family transporter protein 9 153 1.0E-11 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CXR48_RS08880 ad23a67e9b0b1ae626f2b9b4c53d8c5a 77 Hamap MF_01103 UPF0291 protein . 2 60 16.749 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CXR48_RS08880 ad23a67e9b0b1ae626f2b9b4c53d8c5a 77 Gene3D G3DSA:1.10.287.540 4 56 1.3E-24 T 29-03-2018 CXR48_RS08880 ad23a67e9b0b1ae626f2b9b4c53d8c5a 77 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 2.3E-31 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CXR48_RS08880 ad23a67e9b0b1ae626f2b9b4c53d8c5a 77 SUPERFAMILY SSF158221 1 42 3.79E-14 T 29-03-2018 CXR48_RS05160 ab82904f47a4368901ae6bf8325e93c1 185 Pfam PF02632 BioY family 29 172 3.2E-30 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CXR48_RS05160 ab82904f47a4368901ae6bf8325e93c1 185 PIRSF PIRSF016661 1 180 8.0E-38 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CXR48_RS04100 ef32101dfd0659dba64ab4d7a5e9da93 36 Pfam PF14152 YfhE-like protein 3 35 1.8E-9 T 29-03-2018 IPR025437 YfhE-like protein CXR48_RS14225 29912808a37ea8a8a6b99eb9267984ee 52 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 47 2.2E-16 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 CXR48_RS10155 fa803d19de954d3e370e8e7c919d8f10 168 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 73 163 4.3E-28 T 29-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 CXR48_RS11225 e20c9bef7a9103a927bf51d2bc9f7033 75 Pfam PF13025 Protein of unknown function (DUF3886) 8 73 7.0E-20 T 29-03-2018 IPR024980 Protein of unknown function DUF3886 CXR48_RS14175 ba11efd999572a6d490e4ee64b794e01 134 Pfam PF05105 Bacteriophage holin family 18 128 4.6E-25 T 29-03-2018 IPR006480 Bacteriophage holin family CXR48_RS14175 ba11efd999572a6d490e4ee64b794e01 134 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 11 133 9.2E-33 T 29-03-2018 IPR006480 Bacteriophage holin family CXR48_RS16185 9f1cc33c35a9dbe5c6a57b7113a891c8 280 Gene3D G3DSA:3.90.550.10 2 279 4.2E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16185 9f1cc33c35a9dbe5c6a57b7113a891c8 280 SUPERFAMILY SSF53448 7 227 1.45E-56 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CXR48_RS16185 9f1cc33c35a9dbe5c6a57b7113a891c8 280 Pfam PF00535 Glycosyl transferase family 2 10 163 8.1E-33 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CXR48_RS13955 7567cf21e9dac30b6c41f7ba200fdffd 60 Pfam PF10957 Sporulation protein Cse60 2 60 2.6E-34 T 29-03-2018 IPR020296 Sporulation protein Cse60 CXR48_RS13955 7567cf21e9dac30b6c41f7ba200fdffd 60 ProDom PD052690 CSE60 CYTOSOLIC YTEV LJ928 SPORULATION ORF85 PROPHAGE 1 59 1.0E-25 T 29-03-2018 IPR020296 Sporulation protein Cse60 CXR48_RS12060 8c426ac98a01b3d07059884ab038b1d7 84 Pfam PF11116 Protein of unknown function (DUF2624) 1 83 7.7E-33 T 29-03-2018 IPR020277 Protein of unknown function DUF2624 CXR48_RS12060 8c426ac98a01b3d07059884ab038b1d7 84 ProDom PD060869 YQFT IG BH1387 13 68 8.0E-21 T 29-03-2018 IPR020277 Protein of unknown function DUF2624 CXR48_RS05895 2ee978ce08a1b0caa3d9afba64750eb0 622 Pfam PF04740 LXG domain of WXG superfamily 2 200 1.8E-47 T 29-03-2018 IPR006829 LXG domain CXR48_RS18470 5b62c4c0717548840c0b2d686a79793f 426 Pfam PF03600 Citrate transporter 13 372 1.5E-53 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CXR48_RS18470 5b62c4c0717548840c0b2d686a79793f 426 TIGRFAM TIGR00784 citMHS: citrate transporter 1 426 3.7E-237 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 CXR48_RS17025 e62adc8c72b6c4bac5ebb74da031194a 114 Pfam PF13789 Domain of unknown function (DUF4181) 18 108 2.2E-8 T 29-03-2018 IPR025441 Protein of unknown function DUF4181 CXR48_RS06405 5bad6c3c7dcd8ed95ff5adba3356a6e5 715 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 65 223 2.1E-32 T 29-03-2018 CXR48_RS01495 b226cafa2e43c9d341bf1f84d60afa66 466 Pfam PF16244 Domain of unknown function (DUF4901) 22 208 2.4E-15 T 29-03-2018 IPR032599 Protein of unknown function DUF4901 CXR48_RS07080 46b7fba4c5e4ffae822f4a4ba3f5b40e 232 Pfam PF04893 Yip1 domain 21 216 1.1E-26 T 29-03-2018 IPR006977 Yip1 domain GO:0016020 CXR48_RS04020 9fefddd3916d3777739bae7331a85d18 134 Pfam PF07681 DoxX 9 86 7.2E-21 T 29-03-2018 IPR032808 DoxX family CXR48_RS05220 19e52618986dd7dcdec5a0fa1f0438c9 66 Pfam PF11755 Protein of unknown function (DUF3311) 6 64 4.9E-22 T 29-03-2018 IPR021741 Protein of unknown function DUF3311 CXR48_RS08115 e0b3a6c90800f59536457467f5bc33a1 146 Pfam PF03963 Flagellar hook capping protein - N-terminal region 10 79 5.0E-24 T 29-03-2018 IPR005648 Flagellar hook capping protein CXR48_RS09170 2a5649c7585f7f8602b86b27af11b35a 135 Pfam PF04138 GtrA-like protein 11 124 2.0E-27 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CXR48_RS01235 0794eb5ecd703349dd6e979fa63accf8 82 Pfam PF17334 Sigma-G-dependent sporulation-specific SASP protein 1 82 7.6E-35 T 29-03-2018 IPR020255 Sigma-G-dependent sporulation-specific SASP protein CXR48_RS01235 0794eb5ecd703349dd6e979fa63accf8 82 ProDom PD059965 SASP SPORULATION-SPECIFIC SIGMA-G-DEPENDENT SPORULATION SPECIFIC CSGA 1 81 2.0E-26 T 29-03-2018 IPR020255 Sigma-G-dependent sporulation-specific SASP protein CXR48_RS16740 26c9fa1c7caefa759c665b6aba80bafc 398 Pfam PF13692 Glycosyl transferases group 1 221 358 4.3E-12 T 29-03-2018 CXR48_RS16740 26c9fa1c7caefa759c665b6aba80bafc 398 Gene3D G3DSA:3.40.50.2000 175 376 3.8E-23 T 29-03-2018 CXR48_RS16740 26c9fa1c7caefa759c665b6aba80bafc 398 SUPERFAMILY SSF53756 109 386 3.56E-26 T 29-03-2018 CXR48_RS00150 b6cf943aa315a3e538623bf7cb90fe2d 74 Pfam PF10704 Protein of unknown function (DUF2508) 4 70 9.0E-23 T 29-03-2018 IPR019644 Protein of unknown function DUF2508 CXR48_RS13790 e389042d1d6adb87be1875ec21093cd1 271 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 190 207 - T 29-03-2018 IPR000540 Flagellar motor protein MotA, conserved site CXR48_RS13790 e389042d1d6adb87be1875ec21093cd1 271 Pfam PF01618 MotA/TolQ/ExbB proton channel family 105 220 9.8E-24 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CXR48_RS06330 ae55652c1f2d30ca6d7e8a131100d027 192 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 5 148 2.1E-31 T 29-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 CXR48_RS02630 6ac80a54021a9f40bce3920ff0211f61 189 Pfam PF11193 Protein of unknown function (DUF2812) 9 115 7.1E-27 T 29-03-2018 IPR021359 Protein of unknown function DUF2812 CXR48_RS13750 9da38f534f9642caa41e733515fc337e 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 8 104 4.6E-21 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CXR48_RS10970 2628d8f9aef265bfe6e18bf3525931e2 542 Pfam PF05140 ResB-like family 63 428 7.4E-79 T 29-03-2018 IPR007816 ResB-like domain CXR48_RS10970 2628d8f9aef265bfe6e18bf3525931e2 542 Pfam PF05140 ResB-like family 432 519 2.4E-19 T 29-03-2018 IPR007816 ResB-like domain CXR48_RS08765 34bcc948dae430fd71efbeb8570466a9 140 Gene3D G3DSA:2.60.120.260 52 136 7.8E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like CXR48_RS14540 bd8deb759d409995cdb49067a5996eb9 225 Pfam PF04298 Putative neutral zinc metallopeptidase 4 218 1.1E-87 T 29-03-2018 IPR007395 Putative neutral zinc metallopeptidase CXR48_RS18230 5f7a7aff8de1f25ab753b816f99db27e 49 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 9 49 6.2E-16 T 29-03-2018 IPR021008 Protein of unknown function DUF3687 CXR48_RS15310 9731aa18b9312a98dd22727a6b1fb169 116 SUPERFAMILY SSF55718 25 112 6.36E-11 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CXR48_RS15310 9731aa18b9312a98dd22727a6b1fb169 116 Gene3D G3DSA:3.30.1050.10 5 106 2.9E-11 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CXR48_RS15310 9731aa18b9312a98dd22727a6b1fb169 116 Pfam PF02036 SCP-2 sterol transfer family 21 102 5.0E-9 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CXR48_RS15665 5e55a9c5d12c3c1ca30a897f86bcc379 364 Gene3D G3DSA:3.40.1710.10 43 189 2.8E-7 T 29-03-2018 CXR48_RS15665 5e55a9c5d12c3c1ca30a897f86bcc379 364 Pfam PF12698 ABC-2 family transporter protein 19 355 8.9E-31 T 29-03-2018 CXR48_RS03150 367eee40506a7d7da335479c43d0b0fe 253 Pfam PF04536 TPM domain 36 152 4.0E-22 T 29-03-2018 IPR007621 TPM domain CXR48_RS08640 a6b22b0b33c14a03782a1d8d58bc0bbb 134 Pfam PF12788 YmaF family 13 66 4.1E-9 T 29-03-2018 IPR024307 YmaF CXR48_RS10320 6d48394235e6b5b895c06b6959865794 171 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 43 167 8.8E-30 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CXR48_RS10320 6d48394235e6b5b895c06b6959865794 171 Pfam PF05119 Phage terminase, small subunit 52 157 1.5E-27 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CXR48_RS08205 c61a5e3acb4a354f2b6df255b7e3990f 209 Pfam PF04509 CheC-like family 112 147 6.3E-13 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CXR48_RS08205 c61a5e3acb4a354f2b6df255b7e3990f 209 Pfam PF04509 CheC-like family 10 44 3.0E-13 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CXR48_RS08205 c61a5e3acb4a354f2b6df255b7e3990f 209 Gene3D G3DSA:3.40.1550.10 4 208 1.2E-50 T 29-03-2018 IPR028976 CheC-like domain CXR48_RS08205 c61a5e3acb4a354f2b6df255b7e3990f 209 SUPERFAMILY SSF103039 5 206 7.72E-49 T 29-03-2018 IPR028976 CheC-like domain CXR48_RS02735 55f67083e427827a3b6191bd9a519d92 429 Pfam PF03553 Na+/H+ antiporter family 73 209 7.5E-15 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CXR48_RS02735 55f67083e427827a3b6191bd9a519d92 429 Pfam PF03553 Na+/H+ antiporter family 225 420 7.9E-12 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CXR48_RS01400 cce500db0a0c302aeafc302ddfa3e88d 129 Pfam PF07681 DoxX 5 93 1.8E-19 T 29-03-2018 IPR032808 DoxX family CXR48_RS03260 ca60a37fbcf73ebd41cd9b88d9e0e45c 65 Pfam PF14044 NETI protein 8 63 1.5E-27 T 29-03-2018 IPR025930 NETI protein CXR48_RS05020 c86ea8d587a4fe11684ae5975569565b 408 Pfam PF05975 Bacterial ABC transporter protein EcsB 6 384 9.2E-120 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CXR48_RS05020 c86ea8d587a4fe11684ae5975569565b 408 PIRSF PIRSF037259 2 407 2.8E-134 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CXR48_RS00370 56c8cb61295d5330bc7fbd01ced191c8 211 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 7.1E-22 T 29-03-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like CXR48_RS00370 56c8cb61295d5330bc7fbd01ced191c8 211 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 129 2.9E-45 T 29-03-2018 IPR014242 Spore cortex biosynthesis protein, YabQ CXR48_RS02315 db004fb7073ede9b4daab04529aa59ad 350 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 332 3.0E-96 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CXR48_RS02315 db004fb7073ede9b4daab04529aa59ad 350 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 49 304 1.7E-99 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CXR48_RS02315 db004fb7073ede9b4daab04529aa59ad 350 PIRSF PIRSF006470 16 349 2.2E-125 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CXR48_RS07375 6559a088b9093e060fb0c6388bca00e1 207 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 3 161 1.7E-45 T 29-03-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ CXR48_RS07375 6559a088b9093e060fb0c6388bca00e1 207 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 33 159 1.8E-17 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CXR48_RS07035 7a3416fa4972543c00321979ca5834ad 152 Pfam PF00578 AhpC/TSA family 5 125 2.0E-13 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CXR48_RS07035 7a3416fa4972543c00321979ca5834ad 152 SUPERFAMILY SSF52833 2 141 2.02E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold CXR48_RS07035 7a3416fa4972543c00321979ca5834ad 152 Gene3D G3DSA:3.40.30.10 1 152 9.4E-24 T 29-03-2018 CXR48_RS06270 a5fd987bef7d575e990c775a3541db25 148 ProDom PD033466 XKDJ PHAGE PHAGE-LIKE PBSX RELATED LIN1276 ELEMENT YQBJ 1 146 4.0E-61 T 29-03-2018 CXR48_RS02365 d287ef32459e953234f815a93060b3a8 59 Pfam PF13076 Fur-regulated basic protein A 14 48 2.2E-15 T 29-03-2018 IPR025072 Fur-regulated basic protein A CXR48_RS05550 3d446128ce08a710029b9b28d1232138 63 Pfam PF10815 ComZ 4 58 1.2E-32 T 29-03-2018 IPR024558 ComZ CXR48_RS05550 3d446128ce08a710029b9b28d1232138 63 ProDom PD027277 REPRESSOR COMZ COMG OPERON TRANSCRIPTION POSSIBLE COMPETENCE PROTEIN-RELATED BH2888 REGULATION 3 57 2.0E-21 T 29-03-2018 IPR024558 ComZ CXR48_RS11865 fa5e93cd904e955f1792cbb2a597f035 145 PIRSF PIRSF021292 5 145 3.7E-37 T 29-03-2018 IPR016785 ComG operon protein 4 GO:0030420 CXR48_RS11865 fa5e93cd904e955f1792cbb2a597f035 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 31 5.5E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CXR48_RS11865 fa5e93cd904e955f1792cbb2a597f035 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 7.8E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CXR48_RS00190 ba5a30ea0e2fd4f5ab2cf29798d61d32 204 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 10 198 4.0E-61 T 29-03-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein CXR48_RS17010 c7363f7cecb60c2fd129490d5d34f8f9 364 Pfam PF08757 CotH kinase protein 48 355 1.6E-86 T 29-03-2018 IPR014867 Spore coat protein CotH CXR48_RS12880 271fd50ddd3cc07ecd5aac951634822c 288 Pfam PF02163 Peptidase family M50 113 148 1.4E-6 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CXR48_RS01135 5ddbdc64b395f1ecb71eaf651049a938 134 Pfam PF03788 LrgA family 18 108 1.0E-27 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CXR48_RS05340 e1789c96d362d717bbe0210307ab1b29 118 Hamap MF_01536 UPF0344 protein . 1 118 17.404 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 CXR48_RS05340 e1789c96d362d717bbe0210307ab1b29 118 Pfam PF07457 Protein of unknown function (DUF1516) 2 108 1.6E-36 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 CXR48_RS05340 e1789c96d362d717bbe0210307ab1b29 118 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 94 1.0E-36 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 CXR48_RS01145 ac025b825b5a70eba2e12c2af9e456d3 461 PIRSF PIRSF006060 2 460 7.4E-67 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS01145 ac025b825b5a70eba2e12c2af9e456d3 461 Pfam PF00324 Amino acid permease 14 438 1.5E-105 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS01145 ac025b825b5a70eba2e12c2af9e456d3 461 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CXR48_RS17475 e468175f4e2a35fbcda4403102e68748 147 Gene3D G3DSA:3.40.630.30 1 124 2.7E-4 T 29-03-2018 CXR48_RS04715 dbe051987e034ee31512466ca7a811fa 467 PIRSF PIRSF006060 14 466 7.6E-92 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS04715 dbe051987e034ee31512466ca7a811fa 467 Pfam PF13520 Amino acid permease 28 441 3.9E-66 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS04715 dbe051987e034ee31512466ca7a811fa 467 TIGRFAM TIGR00909 2A0306: amino acid transporter 24 456 3.6E-186 T 29-03-2018 IPR004758 Amino acid transporter CXR48_RS01815 0828c3bed494d86cec56f6e3e5888b4a 215 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 198 1.6E-5 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CXR48_RS10965 626a43a1973b2b31c7bccdc9a824a8d0 391 Pfam PF01578 Cytochrome C assembly protein 84 388 3.0E-33 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CXR48_RS10965 626a43a1973b2b31c7bccdc9a824a8d0 391 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 48 391 7.2E-74 T 29-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CXR48_RS02360 bc20a831384b86cd3c51005f73b8c213 48 Pfam PF13040 Fur-regulated basic protein B 3 40 5.3E-17 T 29-03-2018 IPR025004 Transcriptional regulatory protein SenN/SenS CXR48_RS12750 05d3a41b6f72632bf32e053b16af5ae7 98 Pfam PF13797 Post-transcriptional regulator 7 87 1.1E-32 T 29-03-2018 IPR025716 Post-transcriptional regulator CXR48_RS09450 75ed61f5a1231e2a9a544e984066afb3 221 Pfam PF13702 Lysozyme-like 50 203 6.4E-58 T 29-03-2018 CXR48_RS09450 75ed61f5a1231e2a9a544e984066afb3 221 SUPERFAMILY SSF53955 54 160 1.27E-8 T 29-03-2018 IPR023346 Lysozyme-like domain CXR48_RS09450 75ed61f5a1231e2a9a544e984066afb3 221 Gene3D G3DSA:1.10.530.10 48 207 1.1E-11 T 29-03-2018 CXR48_RS09750 db56b51500d9df6532451c83ad273efc 57 ProDom PD052277 YOZD 1 56 2.0E-20 T 29-03-2018 CXR48_RS09750 db56b51500d9df6532451c83ad273efc 57 Pfam PF14162 YozD-like protein 1 57 9.0E-31 T 29-03-2018 IPR025545 YozD-like protein CXR48_RS06620 124ae9196ce748ef8945231bc41a8e08 60 Pfam PF13076 Fur-regulated basic protein A 13 43 2.8E-5 T 29-03-2018 IPR025072 Fur-regulated basic protein A CXR48_RS13095 279a0a1e28f9916ab8853cd6507a70ca 361 Pfam PF10646 Sporulation and spore germination 76 185 1.6E-21 T 29-03-2018 IPR019606 GerMN domain CXR48_RS13095 279a0a1e28f9916ab8853cd6507a70ca 361 Pfam PF10646 Sporulation and spore germination 222 336 2.9E-18 T 29-03-2018 IPR019606 GerMN domain CXR48_RS13095 279a0a1e28f9916ab8853cd6507a70ca 361 SMART SM00909 250 341 5.4E-23 T 29-03-2018 IPR019606 GerMN domain CXR48_RS13095 279a0a1e28f9916ab8853cd6507a70ca 361 SMART SM00909 99 189 1.1E-26 T 29-03-2018 IPR019606 GerMN domain CXR48_RS01555 f548d4ab8779865a7c251cb2f937c501 192 Pfam PF02342 TerD domain 1 188 6.3E-83 T 29-03-2018 IPR003325 TerD domain GO:0006950 CXR48_RS01555 f548d4ab8779865a7c251cb2f937c501 192 Gene3D G3DSA:2.60.60.30 18 187 1.3E-62 T 29-03-2018 CXR48_RS00065 e55bd83dc6daf033b584af24e0b5bd3d 316 Pfam PF14175 YaaC-like Protein 9 310 7.3E-105 T 29-03-2018 IPR026988 YaaC-like protein CXR48_RS08595 b46d1e9accb7ce028901168998cf84d9 251 Pfam PF06912 Protein of unknown function (DUF1275) 31 236 9.7E-40 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 CXR48_RS17670 37622e1e6432c8ff9aa379f9b8eb625d 39 Pfam PF11131 Rap-phr extracellular signalling 3 39 6.4E-13 T 29-03-2018 IPR025899 Phosphatase RapC/F inhibitor, PhrC/F CXR48_RS01710 5dd0d2dd0a0d70ab115f7f375c0d5cbe 411 Pfam PF13556 PucR C-terminal helix-turn-helix domain 349 405 1.5E-17 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CXR48_RS01710 5dd0d2dd0a0d70ab115f7f375c0d5cbe 411 Gene3D G3DSA:1.10.10.60 332 384 4.0E-6 T 29-03-2018 CXR48_RS06985 e9a30d2151369624fbb4e1d843f7fc3b 63 ProDom PD054279 YKZF 6 63 7.0E-23 T 29-03-2018 CXR48_RS06985 e9a30d2151369624fbb4e1d843f7fc3b 63 Pfam PF14156 Antirepressor AbbA 2 62 4.9E-32 T 29-03-2018 IPR025446 Antirepressor AbbA CXR48_RS16690 8c2ba8bf3b1b0d6a1616d55ae1a3c4c4 139 TIGRFAM TIGR03826 YvyF: flagellar operon protein TIGR03826 3 138 1.2E-54 T 29-03-2018 IPR022258 Flagellar operon protein YvyF CXR48_RS05205 4a883af707c4d5be3fea803c4100f5af 89 SMART SM00894 33 88 8.6E-7 T 29-03-2018 IPR008613 Excalibur calcium-binding domain CXR48_RS05205 4a883af707c4d5be3fea803c4100f5af 89 Pfam PF05901 Excalibur calcium-binding domain 34 88 9.7E-15 T 29-03-2018 IPR008613 Excalibur calcium-binding domain CXR48_RS05330 1f39c22f5593844bcd12314c1367e699 69 Pfam PF09388 Spo0E like sporulation regulatory protein 2 37 1.8E-10 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CXR48_RS05330 1f39c22f5593844bcd12314c1367e699 69 SUPERFAMILY SSF140500 2 48 3.66E-12 T 29-03-2018 CXR48_RS08760 81ae7e20ffda0de437537358d2fd4f19 32 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 8 30 2.1E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS08760 81ae7e20ffda0de437537358d2fd4f19 32 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 5 31 2.4E-14 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CXR48_RS15230 3ad7fd90a0f37c15a78a6627f87efe25 90 Pfam PF07853 Protein of unknown function (DUF1648) 13 58 3.8E-12 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 CXR48_RS06700 d2c3932bfacfd2334b4f23c3cd6b166e 340 Pfam PF01757 Acyltransferase family 7 306 1.6E-20 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CXR48_RS15125 b6e6c20089456dc268f07152b85fffec 273 Pfam PF01925 Sulfite exporter TauE/SafE 6 264 1.7E-57 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CXR48_RS12600 e2b806b6e7fb9703bff240a83c03435a 93 Pfam PF06949 Protein of unknown function (DUF1292) 13 87 1.5E-17 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 CXR48_RS12600 e2b806b6e7fb9703bff240a83c03435a 93 Hamap MF_01448 UPF0473 protein . 4 89 22.065 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 CXR48_RS12525 18d6cde9dfa74c1e841a53c8aafe08ad 163 Pfam PF07849 Protein of unknown function (DUF1641) 119 155 2.5E-15 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 CXR48_RS08655 b19b59a6bf52296a67f05f8ca15a7273 91 Pfam PF14157 YmzC-like protein 29 89 5.7E-14 T 29-03-2018 IPR025448 YmzC-like protein CXR48_RS16770 bb00053e87378d04250f25fdd1de9481 482 Pfam PF13440 Polysaccharide biosynthesis protein 32 326 1.9E-71 T 29-03-2018 CXR48_RS05810 8e78ac9ff697cdf98f9ed57425ac7198 84 Pfam PF14069 Stage VI sporulation protein F 6 76 1.1E-26 T 29-03-2018 IPR025942 Stage VI sporulation protein F CXR48_RS00235 4680e09d3ff4dd3fefa83c4e41b5fa98 247 SUPERFAMILY SSF53335 16 198 1.79E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CXR48_RS00235 4680e09d3ff4dd3fefa83c4e41b5fa98 247 Pfam PF05175 Methyltransferase small domain 19 140 1.0E-9 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CXR48_RS00235 4680e09d3ff4dd3fefa83c4e41b5fa98 247 Gene3D G3DSA:3.40.50.150 8 247 2.9E-37 T 29-03-2018 CXR48_RS03245 9e9efbcb0672456b166cc6ff69e08349 260 ProDom PD113106 YVBI TRANSMEMBRANE MEMBRANE YEBC YBEC 62 251 4.0E-54 T 29-03-2018 CXR48_RS10985 408a7f19f34a340aaea8bac73c8a785d 178 Pfam PF07670 Nucleoside recognition 46 146 5.4E-6 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CXR48_RS03380 03fbbbbc241245b3bbc69b6305040317 230 PRINTS PR01837 MgtC/SapB protein signature 97 121 5.8E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS03380 03fbbbbc241245b3bbc69b6305040317 230 PRINTS PR01837 MgtC/SapB protein signature 69 91 5.8E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS03380 03fbbbbc241245b3bbc69b6305040317 230 PRINTS PR01837 MgtC/SapB protein signature 16 35 5.8E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS03380 03fbbbbc241245b3bbc69b6305040317 230 PRINTS PR01837 MgtC/SapB protein signature 35 53 5.8E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS03380 03fbbbbc241245b3bbc69b6305040317 230 Pfam PF02308 MgtC family 13 141 1.1E-32 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CXR48_RS16175 570fbc685108959041244cb6b76bcd89 367 Pfam PF14897 EpsG family 38 362 2.5E-54 T 29-03-2018 CXR48_RS14125 8d9f719aabf752410189f729e123294c 467 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CXR48_RS14125 8d9f719aabf752410189f729e123294c 467 PIRSF PIRSF006060 1 467 1.5E-72 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CXR48_RS14125 8d9f719aabf752410189f729e123294c 467 Pfam PF00324 Amino acid permease 16 445 2.6E-121 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CXR48_RS00375 38bf1297060353b445eca793af5e1974 125 Pfam PF04977 Septum formation initiator 46 122 3.9E-18 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CXR48_RS00375 38bf1297060353b445eca793af5e1974 125 Gene3D G3DSA:1.20.1170.10 3 110 2.6E-4 T 29-03-2018 CXR48_RS04945 072e6c1fc202a1fd5596c2d7a6a4176f 75 Pfam PF14147 Sporulation protein YhaL 4 55 1.4E-27 T 29-03-2018 IPR025428 Sporulation protein YhaL CXR48_RS07365 b2b9045b420e8d37524d5e19a68b6fb4 106 Pfam PF14036 YlaH-like protein 20 94 2.0E-29 T 29-03-2018 IPR025620 YlaH-like protein CXR48_RS05110 09265369f203ca63157f1f64466ef5fb 214 Pfam PF13460 NAD(P)H-binding 7 191 5.4E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS05110 09265369f203ca63157f1f64466ef5fb 214 Gene3D G3DSA:3.40.50.720 1 214 6.3E-38 T 29-03-2018 CXR48_RS05110 09265369f203ca63157f1f64466ef5fb 214 SUPERFAMILY SSF51735 1 201 6.02E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CXR48_RS06685 85b021353367777ac4924f492e940c47 450 Pfam PF02386 Cation transport protein 23 428 3.1E-64 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CXR48_RS06005 f27ba55bdc58eb5f04fbd92c366c34e1 133 Pfam PF10990 Protein of unknown function (DUF2809) 32 115 3.4E-28 T 29-03-2018 IPR021257 Protein of unknown function DUF2809 CXR48_RS01055 b1a772542b6a1d98f4f7a9e0b97377ae 150 Pfam PF04463 Protein of unknown function (DUF523) 2 146 9.4E-42 T 29-03-2018 IPR007553 Domain of unknown function DUF523 CXR48_RS19110 da4b7e4a6ca7d19029ecce4cf8398ee8 395 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 302 3.5E-7 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CXR48_RS19110 da4b7e4a6ca7d19029ecce4cf8398ee8 395 Gene3D G3DSA:3.30.470.20 108 377 1.2E-26 T 29-03-2018 CXR48_RS19110 da4b7e4a6ca7d19029ecce4cf8398ee8 395 SUPERFAMILY SSF56059 111 296 1.5E-23 T 29-03-2018 CXR48_RS07980 cdc98105910c417696dea2b6fa7ec416 128 Pfam PF11068 YlqD protein 1 126 3.9E-36 T 29-03-2018 IPR021297 YlqD protein CXR48_RS10915 a8e51ddf94a828f7244fb1a21ab52db3 195 Pfam PF02517 CAAX protease self-immunity 89 173 8.2E-11 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CXR48_RS04190 9419766c4231e1603b61901988b8d40d 56 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 7 56 5.9E-16 T 29-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 CXR48_RS04190 9419766c4231e1603b61901988b8d40d 56 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 7 56 9.5E-17 T 29-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 CXR48_RS03195 8d559333b4b9002bfd597b1feb590add 69 Pfam PF14169 Cold-inducible protein YdjO 2 59 5.6E-26 T 29-03-2018 IPR025916 Cold-inducible protein YdjO CXR48_RS17000 46a1d920b063a0d18b8d2df0a10d9ff9 224 ProDom PD210561 YWRJ 1 224 2.0E-80 T 29-03-2018 IPR020173 Uncharacterised protein family YwrJ CXR48_RS08890 d99a752d5f08b1872c0f619ce41fd622 148 Pfam PF10747 Sporulation inhibitor of replication protein SirA 3 143 7.9E-44 T 29-03-2018 IPR019683 Sporulation inhibitor of replication protein SirA CXR48_RS05535 c8523ab7e22b0b22bf59e7664b3dd0e6 244 Gene3D G3DSA:3.40.50.1820 23 243 8.9E-10 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS05535 c8523ab7e22b0b22bf59e7664b3dd0e6 244 SUPERFAMILY SSF53474 52 242 3.1E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CXR48_RS04785 19c993f152fc3a6f67bb5f712788d551 34 ProDom PD047280 YHDX 1 33 8.0E-9 T 29-03-2018 IPR035384 Uncharacterized protein YhdX CXR48_RS04785 19c993f152fc3a6f67bb5f712788d551 34 Pfam PF17444 Uncharacterized protein YhdX 1 33 1.5E-21 T 29-03-2018 IPR035384 Uncharacterized protein YhdX CXR48_RS04970 ae67a4c4deada6435e83614f49ac38cd 176 Pfam PF11667 Putative zincin peptidase 59 157 1.1E-18 T 29-03-2018 IPR021683 Putative zincin peptidase CXR48_RS12140 e0179a96aee4e67b9efd93073412fd22 47 Pfam PF14006 YqzL-like protein 3 46 5.8E-20 T 29-03-2018 IPR025617 YqzL-like protein CXR48_RS06665 f52d814a1d74bcc02e5dafe988473232 392 Pfam PF12791 Anti-sigma factor N-terminus 7 54 1.8E-11 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal CXR48_RS01315 9553aec4f75b310a300a91ad4619bd50 162 Pfam PF09335 SNARE associated Golgi protein 29 155 4.2E-28 T 29-03-2018 IPR032816 SNARE associated Golgi protein CXR48_RS01315 9553aec4f75b310a300a91ad4619bd50 162 Gene3D G3DSA:1.20.1250.20 1 160 1.1E-4 T 29-03-2018 CXR48_RS11855 5bb9ead6c18ccc89d057b69e8a5e7342 131 Pfam PF15980 Putative Competence protein ComGF 31 117 2.4E-13 T 29-03-2018 IPR016977 Competence operon G, ComGF CXR48_RS08805 d57e5cc0461994236c9ae66f1797e17b 210 Pfam PF13021 Domain of unknown function (DUF3885) 178 207 2.8E-11 T 29-03-2018 IPR024976 Domain of unknown function DUF3885 CXR48_RS03560 7fcba0ad05df18ea4d44369c8d00c5a7 356 Pfam PF13037 Domain of unknown function (DUF3898) 261 350 7.8E-42 T 29-03-2018 IPR025012 Domain of unknown function DUF3898 CXR48_RS03560 7fcba0ad05df18ea4d44369c8d00c5a7 356 Pfam PF13039 Protein of unknown function (DUF3900) 2 254 1.7E-136 T 29-03-2018 IPR025006 Protein of unknown function DUF3900 CXR48_RS16775 a032b3fc95b4ed1c5e075ecd2ff707b6 219 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 28 219 1.9E-92 T 29-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CXR48_RS16775 a032b3fc95b4ed1c5e075ecd2ff707b6 219 Pfam PF02397 Bacterial sugar transferase 34 212 2.0E-66 T 29-03-2018 IPR003362 Bacterial sugar transferase CXR48_RS15950 4c76ff7aa0c473f73736b0dde0248d9b 596 Gene3D G3DSA:2.60.40.10 153 235 0.0019 T 29-03-2018 IPR013783 Immunoglobulin-like fold CXR48_RS15570 0b16fea06d6aac37b1cc5bae4345ac33 51 Pfam PF12841 YvrJ protein family 12 46 1.7E-16 T 29-03-2018 IPR024419 Protein of unknown function YvrJ CXR48_RS09620 b56003b036635597e241d09e206bc44b 282 Gene3D G3DSA:3.30.750.24 78 281 4.4E-12 T 29-03-2018 IPR002645 STAS domain CXR48_RS09620 b56003b036635597e241d09e206bc44b 282 Pfam PF01740 STAS domain 173 271 5.6E-14 T 29-03-2018 IPR002645 STAS domain CXR48_RS09620 b56003b036635597e241d09e206bc44b 282 SUPERFAMILY SSF52091 164 272 4.32E-17 T 29-03-2018 IPR002645 STAS domain CXR48_RS18105 aa7c7c36013fda36a41d3db67d50d4bf 128 Pfam PF04138 GtrA-like protein 2 119 2.3E-27 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CXR48_RS00995 8157356115191b58c32955bc9262f05b 313 Pfam PF01758 Sodium Bile acid symporter family 32 201 1.3E-20 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CXR48_RS09995 d4fe86deaa68d2353c64e38c5ef978c4 187 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 3 183 4.8E-60 T 29-03-2018 IPR018672 Protein of unknown function DUF2140 CXR48_RS18055 da3a086523eb7ea3b1e8872e3c58ce07 395 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 343 367 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CXR48_RS18055 da3a086523eb7ea3b1e8872e3c58ce07 395 Pfam PF01098 Cell cycle protein 11 385 7.7E-102 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CXR48_RS06290 8d10a0784ab05e5b64df92e23aeda75a 148 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 12 147 9.7E-38 T 29-03-2018 IPR014986 Clostridium phage phiCD119, XkdN CXR48_RS19275 a89a1cd4d5ecf1d942614c575132f03d 127 SUPERFAMILY SSF103481 4 105 6.54E-20 T 29-03-2018 CXR48_RS19275 a89a1cd4d5ecf1d942614c575132f03d 127 Pfam PF00893 Small Multidrug Resistance protein 1 93 7.1E-28 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CXR48_RS03800 64bb3618beb5069a2bef3ffcd7a46a5c 80 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 2.3E-18 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CXR48_RS08130 b2fccbcea6dd9890c992e20b474346c0 139 Pfam PF03748 Flagellar basal body-associated protein FliL 47 139 2.8E-18 T 29-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CXR48_RS06310 5cd65d3a294bff318547bee3ffe8ede6 325 SUPERFAMILY SSF69279 18 150 1.36E-12 T 29-03-2018 CXR48_RS12020 1921911b07eb3340ed99608c30d7b49b 160 Pfam PF04306 Protein of unknown function (DUF456) 21 158 5.7E-39 T 29-03-2018 IPR007403 Protein of unknown function DUF456 CXR48_RS09890 e64dcb31124c3feb1f437808f7b228e5 73 Gene3D G3DSA:3.30.470.30 1 65 5.5E-6 T 29-03-2018 CXR48_RS06495 8ac67837daf22d5baed1b03cc99e91bc 104 SUPERFAMILY SSF103481 6 101 2.62E-17 T 29-03-2018 CXR48_RS06495 8ac67837daf22d5baed1b03cc99e91bc 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 4.2E-29 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CXR48_RS11265 ce00a288ca1306575e1131961673eb07 114 Pfam PF08863 YolD-like protein 20 111 1.1E-18 T 29-03-2018 IPR014962 YolD-like protein CXR48_RS07400 0891196d5967a004dd509d9c1ea36cce 403 Pfam PF01098 Cell cycle protein 13 376 1.5E-116 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CXR48_RS07400 0891196d5967a004dd509d9c1ea36cce 403 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 333 357 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CXR48_RS16755 2d9f1cc5ac4df034cafb6b8c9e960a73 495 Pfam PF04932 O-Antigen ligase 263 409 4.5E-13 T 29-03-2018 IPR007016 O-antigen ligase-related CXR48_RS10530 6ba1b8d6e8180f9d7bc4bcdbff0bf862 137 SUPERFAMILY SSF49764 46 136 1.05E-6 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS10530 6ba1b8d6e8180f9d7bc4bcdbff0bf862 137 Gene3D G3DSA:2.60.40.790 8 137 7.9E-9 T 29-03-2018 IPR008978 HSP20-like chaperone CXR48_RS17640 d107833de44aaa48e7838cb2d242c4f0 239 Pfam PF14256 YwiC-like protein 5 129 5.4E-40 T 29-03-2018 IPR025576 YwiC-like protein CXR48_RS08905 a00d978f03feb532e8b2e73ccd69877e 235 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 7.3E-67 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CXR48_RS03535 5ef9d663efd47484b956a8b397072692 57 Pfam PF10055 Uncharacterized small protein (DUF2292) 11 47 2.0E-16 T 29-03-2018 IPR018743 Protein of unknown function DUF2292 CXR48_RS11700 1075b69f2c71981bbe253fe83269cdee 216 Pfam PF12685 SpoIIIAH-like protein 5 205 1.2E-41 T 29-03-2018 IPR024232 Stage III sporulation protein AH-like CXR48_RS18770 4544e9cb1146b3f58c668177dda53a08 349 Pfam PF00487 Fatty acid desaturase 55 297 3.2E-36 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CXR48_RS00925 5a23f33fe8dad95d79aae8e3fec577e8 147 Pfam PF10730 Protein of unknown function (DUF2521) 1 147 9.6E-54 T 29-03-2018 IPR019667 Uncharacterised protein family YbaK CXR48_RS08950 d36db5015ac33988b34e6f1d53b6047e 41 Pfam PF13040 Fur-regulated basic protein B 2 40 1.4E-15 T 29-03-2018 IPR025004 Transcriptional regulatory protein SenN/SenS CXR48_RS14075 28a5035338c36fb25b6ebf0fcb8605e1 90 Pfam PF10732 Protein of unknown function (DUF2524) 1 84 2.4E-38 T 29-03-2018 IPR019668 Uncharacterised protein family YtzC CXR48_RS10280 61877de4108341a6f4583106b6e3508b 132 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 12 97 4.1E-8 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CXR48_RS10280 61877de4108341a6f4583106b6e3508b 132 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 8 131 5.5E-17 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CXR48_RS02720 b936c0a717c6c1f307cc5eecf48a5cb4 320 Pfam PF01758 Sodium Bile acid symporter family 43 220 1.1E-17 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CXR48_RS17730 c091e042d5af5eb374bfbc81a21decd6 172 Pfam PF08741 YwhD family 6 166 4.5E-86 T 29-03-2018 IPR014852 Uncharacterised protein YwhD CXR48_RS05300 02d0393ca1501393e10539c971d4a95f 72 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 3.6E-27 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CXR48_RS03510 ce68c498953c0f96ce133f61765c7104 92 Pfam PF14150 YesK-like protein 4 82 1.4E-14 T 29-03-2018 IPR025434 YesK-like protein CXR48_RS04140 8ea009849c5230d61cdd01fb06c2b717 89 Pfam PF14043 WVELL protein 4 73 8.1E-37 T 29-03-2018 IPR026952 WVELL protein CXR48_RS14435 695deafc1ca52676e8f4d689d8bb2a46 179 ProDom PD034110 YWEA MEMBRANE YUAB TRANSMEMBRANE ORF-1 45 168 1.0E-53 T 29-03-2018 IPR034650 YuaB-like CXR48_RS02775 beea66270e4efa6ac740184e767a42e7 65 Gene3D G3DSA:1.20.1260.10 2 65 1.4E-6 T 29-03-2018 IPR012347 Ferritin-related CXR48_RS14720 a3a070cbb2c990a5314ce666ce145933 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 5.7E-32 T 29-03-2018 CXR48_RS14930 e0e42eb7055f91f65945afd825325263 158 Pfam PF02681 Divergent PAP2 family 6 148 4.1E-50 T 29-03-2018 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related CXR48_RS14930 e0e42eb7055f91f65945afd825325263 158 Gene3D G3DSA:1.20.144.10 4 153 5.8E-5 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CXR48_RS14665 e5d02e8b3ea63e7fc4f79cb1f0ca63ac 137 Pfam PF04134 Protein of unknown function, DUF393 11 120 1.7E-37 T 29-03-2018 IPR007263 Protein of unknown function DUF393 CXR48_RS03765 7f6e60bedb632ad9c66ff24cb19ecc2c 103 Pfam PF11588 Protein of unknown function (DUF3243) 24 101 3.5E-28 T 29-03-2018 IPR021637 Protein of unknown function DUF3243 CXR48_RS05795 41ec305fc0fe72eb560281dc8a802ab2 118 Pfam PF07098 Protein of unknown function (DUF1360) 10 112 7.2E-36 T 29-03-2018 IPR010773 Mycobacterium phage PG1, Gp7 CXR48_RS05690 aba00c05686522c6c94ffdc761b8b744 121 Hamap MF_01861 UPF0738 protein . 3 121 27.499 T 29-03-2018 IPR020908 Uncharacterised protein family UPF0738 CXR48_RS06575 99c139b52538a8cb06f2bb55040ba62f 253 Pfam PF02361 Cobalt transport protein 7 220 4.2E-41 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CXR48_RS19225 9b458adc647b7732ee0859c3e7341fde 288 Pfam PF07485 Domain of Unknown Function (DUF1259) 160 279 9.7E-34 T 29-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO CXR48_RS19225 9b458adc647b7732ee0859c3e7341fde 288 Pfam PF07485 Domain of Unknown Function (DUF1259) 14 133 6.6E-35 T 29-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO CXR48_RS12810 310621e15e25538ea2d2d94d01216cf0 197 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 15 196 2.1E-22 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CXR48_RS10845 c3a3eab2a33690c227823047db6cd521 43 Pfam PF14140 YpzI-like protein 1 42 2.1E-25 T 29-03-2018 IPR025414 YpzI-like protein CXR48_RS05095 f6075ad337a86bbbc5665de2eb536aef 44 Pfam PF14149 YhfH-like protein 2 38 4.3E-14 T 29-03-2018 IPR025432 YhfH-like protein CXR48_RS10795 47a14b8b9738edfd56deefbd769e80dd 251 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 21 194 1.3E-72 T 29-03-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 CXR48_RS07760 3b529af5210b03efb20adb53db8cd6e0 354 Pfam PF01384 Phosphate transporter family 16 305 4.6E-44 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CXR48_RS01090 afeb9a5fceb0131f0ba3bd442b7c7836 208 Pfam PF13490 Putative zinc-finger 3 37 2.5E-6 T 29-03-2018 IPR027383 Putative zinc-finger CXR48_RS06385 96605430d7e8ef69992fb99ba6a252ef 332 Pfam PF01384 Phosphate transporter family 22 320 5.3E-91 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CXR48_RS01500 b956251a1216498ab6c561103691efad 452 Pfam PF16244 Domain of unknown function (DUF4901) 8 193 1.6E-15 T 29-03-2018 IPR032599 Protein of unknown function DUF4901 CXR48_RS13915 484105a85bdb5da5fece1a900e78de91 386 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 382 3.2E-35 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CXR48_RS10700 45039b60d2376ed2e1b3cf8d45621697 148 Pfam PF10673 Protein of unknown function (DUF2487) 9 145 3.2E-43 T 29-03-2018 IPR019615 Protein of unknown function DUF2487 CXR48_RS03545 ba55751c7b16ffa773c576a7da71ff8a 214 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 20 207 1.2E-34 T 29-03-2018 IPR006214 Bax inhibitor 1-related