locus-tag	class	description
LCH16_RS00010	COG0592	DNA-directed DNA polymerase activity
LCH16_RS00015	COG2501	S4 domain
LCH16_RS00030	COG0187	DNA topoisomerase II activity
LCH16_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCH16_RS00070	COG0516	GMP reductase activity
LCH16_RS00070	COG0517	IMP dehydrogenase activity
LCH16_RS00075	COG1686	Belongs to the peptidase S11 family
LCH16_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
LCH16_RS00105	COG1428	Deoxynucleoside kinase
LCH16_RS00110	COG1428	Deoxynucleoside kinase
LCH16_RS00115	COG1388	LysM domain
LCH16_RS00115	COG3858	chitin binding
LCH16_RS00120	COG1335	isochorismatase
LCH16_RS00125	COG0590	tRNA wobble adenosine to inosine editing
LCH16_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCH16_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LCH16_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LCH16_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LCH16_RS00195	COG3853	Toxic anion resistance protein (TelA)
LCH16_RS00200	COG1982	Orn Lys Arg decarboxylase major
LCH16_RS00210	COG3870	Protein conserved in bacteria
LCH16_RS00215	COG1728	Protein conserved in bacteria
LCH16_RS00220	COG0470	DNA polymerase III
LCH16_RS00225	COG1774	PSP1 C-terminal conserved region
LCH16_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LCH16_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LCH16_RS00250	COG2002	toxin-antitoxin pair type II binding
LCH16_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCH16_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCH16_RS00260	COG0084	hydrolase, TatD family'
LCH16_RS00265	COG3583	domain protein
LCH16_RS00265	COG3584	3D domain protein
LCH16_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LCH16_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LCH16_RS00285	COG4466	Protein conserved in bacteria
LCH16_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCH16_RS00305	COG0251	oxidation-reduction process
LCH16_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCH16_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCH16_RS00345	COG2002	toxin-antitoxin pair type II binding
LCH16_RS00350	COG2244	polysaccharide biosynthetic process
LCH16_RS00355	COG3956	TIGRFAM MazG family protein
LCH16_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LCH16_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LCH16_RS00380	COG1098	S1 RNA binding domain
LCH16_RS00395	COG2208	phosphoserine phosphatase activity
LCH16_RS00400	COG2304	oxidoreductase activity
LCH16_RS00405	COG0515	serine threonine protein kinase
LCH16_RS00410	COG0037	tRNA processing
LCH16_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LCH16_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCH16_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCH16_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LCH16_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LCH16_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
LCH16_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCH16_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LCH16_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LCH16_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LCH16_RS00475	COG1396	sequence-specific DNA binding
LCH16_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCH16_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LCH16_RS00565	COG4463	regulation of RNA biosynthetic process
LCH16_RS00570	COG3880	PFAM UvrB UvrC protein
LCH16_RS00580	COG0542	response to heat
LCH16_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LCH16_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LCH16_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
LCH16_RS00615	COG1045	serine acetyltransferase
LCH16_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LCH16_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCH16_RS00635	COG3688	RNA-binding protein containing a PIN domain
LCH16_RS00640	COG1595	DNA-templated transcription, initiation
LCH16_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LCH16_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
LCH16_RS00680	COG2813	Specifically methylates the guanine in position
LCH16_RS00695	COG1358	cellular component organization or biogenesis
LCH16_RS00720	COG0596	Alpha beta hydrolase
LCH16_RS00830	COG0201	protein transport
LCH16_RS00840	COG0024	Methionine aminopeptidase
LCH16_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LCH16_RS00880	COG1122	ATPase activity
LCH16_RS00885	COG1122	ATPase activity
LCH16_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCH16_RS00910	COG2226	methyltransferase
LCH16_RS00915	COG2318	DinB family
LCH16_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCH16_RS00930	COG0489	protein tyrosine kinase activity
LCH16_RS00940	COG2194	sulfuric ester hydrolase activity
LCH16_RS00945	COG0726	polysaccharide deacetylase
LCH16_RS01005	COG0738	Major facilitator superfamily
LCH16_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LCH16_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
LCH16_RS01030	COG0385	Bile acid
LCH16_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCH16_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCH16_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCH16_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCH16_RS01055	COG2207	Transcriptional regulator
LCH16_RS01060	COG3876	Protein conserved in bacteria
LCH16_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
LCH16_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCH16_RS01075	COG1263	PTS System
LCH16_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCH16_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCH16_RS01090	COG1683	Conserved Protein
LCH16_RS01120	COG1595	DNA-templated transcription, initiation
LCH16_RS01125	COG5662	AntiSigma factor
LCH16_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LCH16_RS01135	COG4856	YbbR-like protein
LCH16_RS01175	COG1346	cytolysis
LCH16_RS01180	COG1380	Effector of murein hydrolase LrgA
LCH16_RS01185	COG1846	Transcriptional regulator
LCH16_RS01190	COG1113	amino acid transport
LCH16_RS01195	COG1011	Hydrolase
LCH16_RS01200	COG4585	Histidine kinase
LCH16_RS01205	COG2197	response regulator
LCH16_RS01210	COG1131	(ABC) transporter
LCH16_RS01230	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LCH16_RS01250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS01250	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS01250	COG3321	synthase
LCH16_RS01250	COG4221	oxidoreductase activity
LCH16_RS01255	COG0300	oxidoreductase activity
LCH16_RS01255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS01255	COG3321	synthase
LCH16_RS01255	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS01295	COG0531	amino acid
LCH16_RS01305	COG0584	glycerophosphoryl diester phosphodiesterase
LCH16_RS01310	COG2271	Major facilitator Superfamily
LCH16_RS01320	COG2368	4-hydroxyphenylacetate
LCH16_RS01330	COG3409	Peptidoglycan-binding domain 1 protein
LCH16_RS01345	COG0371	Dehydrogenase
LCH16_RS01355	COG1183	phosphatidylcholine synthase activity
LCH16_RS01360	COG0586	Pfam SNARE associated Golgi protein
LCH16_RS01365	COG0688	phosphatidylethanolamine metabolic process
LCH16_RS01380	COG1301	dicarboxylic acid transport
LCH16_RS01385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCH16_RS01395	COG2040	homocysteine
LCH16_RS01400	COG1115	amino acid carrier protein
LCH16_RS01405	COG2066	Belongs to the glutaminase family
LCH16_RS01410	COG4191	Histidine kinase
LCH16_RS01415	COG0784	Response regulator, receiver
LCH16_RS01435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCH16_RS01440	COG0778	Nitroreductase
LCH16_RS01445	COG0346	lactoylglutathione lyase activity
LCH16_RS01450	COG2259	Doxx family
LCH16_RS01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCH16_RS01465	COG3773	Cell wall hydrolase
LCH16_RS01470	COG3540	Alkaline phosphatase
LCH16_RS01475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LCH16_RS01480	COG0805	protein transport
LCH16_RS01490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCH16_RS01495	COG0477	Major facilitator Superfamily
LCH16_RS01500	COG1309	transcriptional regulator
LCH16_RS01505	COG0252	asparaginase activity
LCH16_RS01510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LCH16_RS01515	COG3012	SEC-C Motif Domain Protein
LCH16_RS01515	COG1405	negative regulation of cell septum assembly
LCH16_RS01520	COG0667	Aldo Keto reductase
LCH16_RS01530	COG1595	DNA-templated transcription, initiation
LCH16_RS01535	COG1595	DNA-templated transcription, initiation
LCH16_RS01540	COG1876	peptidase activity
LCH16_RS01545	COG0457	Tetratricopeptide repeat
LCH16_RS01550	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS01555	COG0366	Alpha amylase catalytic
LCH16_RS01560	COG0803	Belongs to the bacterial solute-binding protein 9 family
LCH16_RS01565	COG1121	(ABC) transporter
LCH16_RS01570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LCH16_RS01575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCH16_RS01580	COG2310	stress, protein
LCH16_RS01585	COG2310	stress, protein
LCH16_RS01590	COG2310	stress, protein
LCH16_RS01595	COG0861	Integral membrane protein TerC family
LCH16_RS01605	COG3853	Toxic anion resistance protein (TelA)
LCH16_RS01610	COG0477	Major facilitator Superfamily
LCH16_RS01615	COG0517	IMP dehydrogenase activity
LCH16_RS01615	COG4175	Glycine betaine
LCH16_RS01620	COG4176	ABC-type proline glycine betaine transport system permease component
LCH16_RS01625	COG2113	Glycine betaine
LCH16_RS01630	COG1473	amidohydrolase
LCH16_RS01635	COG1288	antiporter activity
LCH16_RS01645	COG0366	Alpha amylase catalytic
LCH16_RS01655	COG2814	Major facilitator Superfamily
LCH16_RS01660	COG1846	Transcriptional regulator
LCH16_RS01665	COG1280	lysine exporter protein (LysE YggA)
LCH16_RS01670	COG3403	YqcI/YcgG family
LCH16_RS01675	COG1113	amino acid transport
LCH16_RS01680	COG3665	Urea carboxylase-associated protein
LCH16_RS01695	COG1660	Displays ATPase and GTPase activities
LCH16_RS01700	COG1082	Xylose isomerase domain protein TIM barrel
LCH16_RS01705	COG2271	Major facilitator Superfamily
LCH16_RS01710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LCH16_RS01715	COG3458	cephalosporin-C deacetylase activity
LCH16_RS01720	COG3541	Predicted nucleotidyltransferase
LCH16_RS01725	COG0506	proline dehydrogenase activity
LCH16_RS01730	COG1012	belongs to the aldehyde dehydrogenase family
LCH16_RS01735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCH16_RS01740	COG2508	Transcriptional regulator
LCH16_RS01750	COG1587	Uroporphyrinogen-III synthase
LCH16_RS01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LCH16_RS01755	COG2146	nitrite reductase [NAD(P)H] activity
LCH16_RS01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LCH16_RS01765	COG0243	molybdopterin cofactor binding
LCH16_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LCH16_RS01775	COG2223	nitrite transmembrane transporter activity
LCH16_RS01780	COG0523	cobalamin synthesis protein
LCH16_RS01785	COG1063	alcohol dehydrogenase
LCH16_RS01790	COG1714	RDD family
LCH16_RS01800	COG2723	6-phospho-beta-galactosidase activity
LCH16_RS01810	COG3209	COG3209 Rhs family protein
LCH16_RS01815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LCH16_RS01820	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LCH16_RS01825	COG1733	regulation of RNA biosynthetic process
LCH16_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS01850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS01855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS01860	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LCH16_RS01875	COG0697	spore germination
LCH16_RS01880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCH16_RS01890	COG2364	Membrane
LCH16_RS01895	COG1126	abc transporter atp-binding protein
LCH16_RS01900	COG0765	amino acid transport
LCH16_RS01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCH16_RS01910	COG0583	DNA-binding transcription factor activity
LCH16_RS01915	COG0163	prenyltransferase activity
LCH16_RS01920	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LCH16_RS01935	COG3104	oligopeptide transport
LCH16_RS01940	COG5434	Belongs to the glycosyl hydrolase 28 family
LCH16_RS01950	COG0697	spore germination
LCH16_RS01960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LCH16_RS01965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCH16_RS01970	COG0456	acetyltransferase
LCH16_RS01975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCH16_RS01980	COG0765	amino acid transport
LCH16_RS01985	COG1126	abc transporter atp-binding protein
LCH16_RS01990	COG1473	amidohydrolase
LCH16_RS01995	COG2079	MmgE PrpD family protein
LCH16_RS02000	COG1136	(ABC) transporter
LCH16_RS02005	COG0577	efflux transmembrane transporter activity
LCH16_RS02010	COG0745	RESPONSE REGULATOR receiver
LCH16_RS02015	COG3850	Histidine kinase
LCH16_RS02015	COG5002	protein histidine kinase activity
LCH16_RS02020	COG0457	Tetratricopeptide repeat
LCH16_RS02035	COG0527	aspartate kinase activity
LCH16_RS02040	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCH16_RS02045	COG4605	iron ion homeostasis
LCH16_RS02050	COG4604	ABC transporter, ATP-binding protein
LCH16_RS02055	COG4607	ABC-type enterochelin transport system periplasmic component
LCH16_RS02060	COG2814	Major facilitator Superfamily
LCH16_RS02065	COG1309	transcriptional regulator
LCH16_RS02070	COG0778	Nitroreductase
LCH16_RS02075	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LCH16_RS02080	COG0640	Transcriptional regulator
LCH16_RS02085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCH16_RS02090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LCH16_RS02095	COG1012	belongs to the aldehyde dehydrogenase family
LCH16_RS02100	COG4975	Glucose uptake
LCH16_RS02105	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS02110	COG4549	nuclear export factor GLE1
LCH16_RS02115	COG1276	copper resistance
LCH16_RS02115	COG2372	response to copper ion
LCH16_RS02120	COG1349	DNA-binding transcription factor activity
LCH16_RS02130	COG2213	PTS system mannitol-specific
LCH16_RS02135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCH16_RS02145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LCH16_RS02155	COG0561	phosphatase activity
LCH16_RS02165	COG1914	H( )-stimulated, divalent metal cation uptake system
LCH16_RS02175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LCH16_RS02180	COG1984	allophanate hydrolase subunit 2
LCH16_RS02185	COG1414	Transcriptional regulator
LCH16_RS02190	COG2755	lipolytic protein G-D-S-L family
LCH16_RS02200	COG2329	Antibiotic biosynthesis monooxygenase
LCH16_RS02205	COG0768	penicillin binding
LCH16_RS02210	COG4989	oxidoreductase activity
LCH16_RS02215	COG3711	transcriptional antiterminator
LCH16_RS02220	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS02225	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS02230	COG1917	Cupin 2, conserved barrel domain protein
LCH16_RS02235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCH16_RS02240	COG3871	stress protein (general stress protein 26)
LCH16_RS02255	COG1522	sequence-specific DNA binding
LCH16_RS02260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCH16_RS02260	COG0551	DNA topoisomerase type I activity
LCH16_RS02265	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LCH16_RS02270	COG3706	GGDEF domain
LCH16_RS02275	COG5298	Protein conserved in bacteria
LCH16_RS02280	COG1215	transferase activity, transferring glycosyl groups
LCH16_RS02290	COG0531	amino acid
LCH16_RS02295	COG0494	nUDIX hydrolase
LCH16_RS02300	COG0028	Belongs to the TPP enzyme family
LCH16_RS02350	COG1914	H( )-stimulated, divalent metal cation uptake system
LCH16_RS02370	COG2076	Multidrug Resistance protein
LCH16_RS02375	COG2217	Heavy metal translocating P-type atpase
LCH16_RS02380	COG3729	General stress protein
LCH16_RS02385	COG0662	Cupin 2, conserved barrel domain protein
LCH16_RS02390	COG2329	Antibiotic biosynthesis monooxygenase
LCH16_RS02395	COG3546	catalase activity
LCH16_RS02400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LCH16_RS02405	COG3290	protein histidine kinase activity
LCH16_RS02410	COG4565	transcriptional regulatory protein
LCH16_RS02415	COG1301	dicarboxylic acid transport
LCH16_RS02420	COG0628	permease
LCH16_RS02425	COG1131	(ABC) transporter
LCH16_RS02430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LCH16_RS02440	COG1960	acyl-CoA dehydrogenase activity
LCH16_RS02455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCH16_RS02460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCH16_RS02470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCH16_RS02475	COG0513	Belongs to the DEAD box helicase family
LCH16_RS02480	COG3402	PFAM membrane-flanked domain
LCH16_RS02485	COG3428	Bacterial PH domain
LCH16_RS02490	COG0705	Rhomboid family
LCH16_RS02500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LCH16_RS02505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LCH16_RS02510	COG0864	Transcriptional regulator
LCH16_RS02515	COG2337	Toxic component of a toxin-antitoxin (TA) module
LCH16_RS02520	COG1366	Belongs to the anti-sigma-factor antagonist family
LCH16_RS02525	COG1366	Belongs to the anti-sigma-factor antagonist family
LCH16_RS02530	COG2172	sigma factor antagonist activity
LCH16_RS02535	COG2208	phosphoserine phosphatase activity
LCH16_RS02540	COG1366	Belongs to the anti-sigma-factor antagonist family
LCH16_RS02550	COG1191	sigma factor activity
LCH16_RS02555	COG2208	phosphoserine phosphatase activity
LCH16_RS02560	COG2183	response to ionizing radiation
LCH16_RS02635	COG5444	nuclease activity
LCH16_RS02640	COG2249	NAD(P)H dehydrogenase (quinone) activity
LCH16_RS02655	COG0477	Major facilitator Superfamily
LCH16_RS02675	COG2030	dehydratase
LCH16_RS02685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCH16_RS02690	COG1959	2 iron, 2 sulfur cluster binding
LCH16_RS02695	COG2910	NAD(P)H-binding
LCH16_RS02700	COG1278	Cold shock
LCH16_RS02705	COG1329	Transcriptional regulator
LCH16_RS02710	COG1794	racemase activity, acting on amino acids and derivatives
LCH16_RS02725	COG3621	Patatin-like phospholipase
LCH16_RS02735	COG0662	Cupin 2, conserved barrel domain protein
LCH16_RS02750	COG0277	FAD linked oxidase domain protein
LCH16_RS02775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LCH16_RS02810	COG0351	phosphomethylpyrimidine kinase
LCH16_RS02825	COG1064	alcohol dehydrogenase
LCH16_RS02830	COG0789	Transcriptional regulator
LCH16_RS02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCH16_RS02855	COG2814	Major facilitator Superfamily
LCH16_RS02860	COG1309	transcriptional regulator
LCH16_RS02865	COG0697	spore germination
LCH16_RS02870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCH16_RS02875	COG5577	PFAM Coat F domain
LCH16_RS02885	COG1063	alcohol dehydrogenase
LCH16_RS02890	COG5577	PFAM Coat F domain
LCH16_RS02900	COG4585	Histidine kinase
LCH16_RS02905	COG2197	response regulator
LCH16_RS02910	COG2409	Drug exporters of the RND superfamily
LCH16_RS02915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LCH16_RS02920	COG0488	(ABC) transporter
LCH16_RS02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCH16_RS02935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCH16_RS02945	COG2814	Major facilitator Superfamily
LCH16_RS02950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LCH16_RS02960	COG0730	response to heat
LCH16_RS02965	COG0456	acetyltransferase
LCH16_RS02975	COG1051	belongs to the nudix hydrolase family
LCH16_RS02980	COG2226	methyltransferase
LCH16_RS03000	COG1802	Transcriptional regulator
LCH16_RS03005	COG1819	glycosyl
LCH16_RS03020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCH16_RS03030	COG1388	LysM domain
LCH16_RS03035	COG2814	Major facilitator Superfamily
LCH16_RS03040	COG2188	Transcriptional regulator
LCH16_RS03045	COG2186	Transcriptional regulator
LCH16_RS03050	COG2807	transmembrane transport
LCH16_RS03055	COG2076	Multidrug Resistance protein
LCH16_RS03060	COG2076	Multidrug Resistance protein
LCH16_RS03065	COG1309	transcriptional regulator
LCH16_RS03070	COG0531	amino acid
LCH16_RS03080	COG3832	glyoxalase III activity
LCH16_RS03085	COG0604	alcohol dehydrogenase
LCH16_RS03090	COG2814	Major facilitator Superfamily
LCH16_RS03130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LCH16_RS03135	COG0802	atpase or kinase
LCH16_RS03140	COG1214	PFAM Peptidase M22, glycoprotease
LCH16_RS03145	COG0456	acetyltransferase
LCH16_RS03150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LCH16_RS03155	COG0488	(ABC) transporter
LCH16_RS03170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LCH16_RS03175	COG0805	protein transport
LCH16_RS03185	COG1266	CAAX protease self-immunity
LCH16_RS03200	COG0745	RESPONSE REGULATOR receiver
LCH16_RS03215	COG3290	protein histidine kinase activity
LCH16_RS03295	COG0457	Tetratricopeptide repeat
LCH16_RS03300	COG1063	alcohol dehydrogenase
LCH16_RS03305	COG2211	Major facilitator Superfamily
LCH16_RS03310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCH16_RS03320	COG1842	Phage shock protein A
LCH16_RS03325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCH16_RS03330	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LCH16_RS03335	COG4260	virion core protein, lumpy skin disease virus
LCH16_RS03340	COG2755	lipolytic protein G-D-S-L family
LCH16_RS03340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LCH16_RS03350	COG1595	DNA-templated transcription, initiation
LCH16_RS03355	COG1063	alcohol dehydrogenase
LCH16_RS03360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LCH16_RS03365	COG0823	Involved in the tonB-independent uptake of proteins
LCH16_RS03380	COG2132	Multicopper oxidase
LCH16_RS03385	COG1113	amino acid transport
LCH16_RS03390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCH16_RS03395	COG0714	Associated with various cellular activities
LCH16_RS03400	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LCH16_RS03405	COG1305	Transglutaminase-like
LCH16_RS03440	COG2252	PERMEase
LCH16_RS03445	COG3064	Membrane
LCH16_RS03465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LCH16_RS03470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCH16_RS03475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LCH16_RS03480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LCH16_RS03485	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCH16_RS03500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LCH16_RS03510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LCH16_RS03515	COG0138	bifunctional purine biosynthesis protein purh
LCH16_RS03520	COG0151	Belongs to the GarS family
LCH16_RS03535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LCH16_RS03540	COG1470	cell adhesion involved in biofilm formation
LCH16_RS03545	COG4496	protein, YerC YecD
LCH16_RS03550	COG0069	glutamate synthase activity
LCH16_RS03560	COG0210	DNA helicase
LCH16_RS03570	COG4851	CamS sex pheromone cAM373 precursor
LCH16_RS03575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LCH16_RS03580	COG1285	pathogenesis
LCH16_RS03585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCH16_RS03605	COG1309	transcriptional regulator
LCH16_RS03610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LCH16_RS03615	COG1597	lipid kinase activity
LCH16_RS03620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCH16_RS03630	COG1131	(ABC) transporter
LCH16_RS03680	COG5444	nuclease activity
LCH16_RS03705	COG3546	catalase activity
LCH16_RS03710	COG0454	-acetyltransferase
LCH16_RS03720	COG2323	membrane
LCH16_RS03725	COG2329	Antibiotic biosynthesis monooxygenase
LCH16_RS03730	COG0346	lactoylglutathione lyase activity
LCH16_RS03735	COG1366	Belongs to the anti-sigma-factor antagonist family
LCH16_RS03740	COG5583	Uncharacterized small protein (DUF2292)
LCH16_RS03745	COG0196	riboflavin kinase activity
LCH16_RS03750	COG0670	Belongs to the BI1 family
LCH16_RS03755	COG1846	Transcriptional regulator
LCH16_RS03760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LCH16_RS03770	COG2124	cytochrome p450
LCH16_RS03770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LCH16_RS03775	COG1368	sulfuric ester hydrolase activity
LCH16_RS03780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LCH16_RS03785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCH16_RS03790	COG1442	glycosyl transferase family 8
LCH16_RS03795	COG1216	Glycosyl transferase, family 2
LCH16_RS03800	COG1442	glycosyl transferase family 8
LCH16_RS03805	COG2223	nitrite transmembrane transporter activity
LCH16_RS03810	COG0531	amino acid
LCH16_RS03815	COG1012	belongs to the aldehyde dehydrogenase family
LCH16_RS03820	COG0840	transmembrane signaling receptor activity
LCH16_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS03830	COG0463	Glycosyl transferase, family 2
LCH16_RS03830	COG0457	Tetratricopeptide repeat
LCH16_RS03835	COG0488	(ABC) transporter
LCH16_RS03840	COG0789	Transcriptional regulator
LCH16_RS03845	COG2814	Major facilitator Superfamily
LCH16_RS03850	COG0488	(ABC) transporter
LCH16_RS03855	COG0513	Belongs to the DEAD box helicase family
LCH16_RS03860	COG0456	acetyltransferase
LCH16_RS03865	COG2130	NADP-dependent
LCH16_RS03880	COG3866	Pectate lyase
LCH16_RS03885	COG0471	metal ion transport
LCH16_RS03910	COG0745	RESPONSE REGULATOR receiver
LCH16_RS03910	COG2972	Histidine kinase
LCH16_RS03920	COG3279	Response regulator of the LytR AlgR family
LCH16_RS03930	COG3764	Sortase (surface protein transpeptidase)
LCH16_RS03935	COG3290	protein histidine kinase activity
LCH16_RS03940	COG4565	transcriptional regulatory protein
LCH16_RS03945	COG3181	Tripartite tricarboxylate transporter family receptor
LCH16_RS03950	COG2851	Citrate transporter
LCH16_RS03955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCH16_RS03960	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LCH16_RS03970	COG2258	MOSC domain
LCH16_RS03990	COG0024	Methionine aminopeptidase
LCH16_RS03995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCH16_RS03995	COG1263	PTS System
LCH16_RS04005	COG1368	sulfuric ester hydrolase activity
LCH16_RS04015	COG0071	Belongs to the small heat shock protein (HSP20) family
LCH16_RS04030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCH16_RS04030	COG1263	PTS System
LCH16_RS04035	COG0366	Alpha amylase catalytic
LCH16_RS04040	COG2188	Transcriptional regulator
LCH16_RS04045	COG0778	Nitroreductase
LCH16_RS04060	COG0737	Belongs to the 5'-nucleotidase family
LCH16_RS04065	COG0693	protein deglycase activity
LCH16_RS04070	COG1609	Transcriptional regulator
LCH16_RS04085	COG2814	Major facilitator Superfamily
LCH16_RS04095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LCH16_RS04100	COG4980	gas vesicle protein
LCH16_RS04105	COG1295	ribonuclease BN
LCH16_RS04110	COG0477	Major facilitator Superfamily
LCH16_RS04115	COG0387	Pfam Sodium calcium exchanger
LCH16_RS04125	COG0668	transmembrane transport
LCH16_RS04130	COG0535	radical SAM domain protein
LCH16_RS04140	COG0726	polysaccharide deacetylase
LCH16_RS04145	COG2084	Dehydrogenase
LCH16_RS04155	COG0598	Magnesium transport protein CorA
LCH16_RS04160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LCH16_RS04165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCH16_RS04180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCH16_RS04185	COG4637	Psort location Cytoplasmic, score
LCH16_RS04190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LCH16_RS04195	COG0022	dehydrogenase e1 component
LCH16_RS04200	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCH16_RS04205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCH16_RS04210	COG3284	Transcriptional regulator
LCH16_RS04220	COG1486	melibiose metabolic process
LCH16_RS04225	COG1737	Transcriptional regulator
LCH16_RS04230	COG1263	PTS System
LCH16_RS04230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCH16_RS04235	COG5434	Belongs to the glycosyl hydrolase 28 family
LCH16_RS04240	COG1132	(ABC) transporter
LCH16_RS04245	COG1132	(ABC) transporter
LCH16_RS04250	COG2259	Doxx family
LCH16_RS04255	COG2514	catechol 2,3-dioxygenase activity
LCH16_RS04265	COG1695	Transcriptional regulator
LCH16_RS04270	COG2249	NAD(P)H dehydrogenase (quinone) activity
LCH16_RS04275	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LCH16_RS04280	COG0574	Belongs to the PEP-utilizing enzyme family
LCH16_RS04280	COG3848	Pyruvate phosphate dikinase
LCH16_RS04285	COG2732	(Barnase) inhibitor
LCH16_RS04290	COG2318	DinB family
LCH16_RS04295	COG2814	Major facilitator Superfamily
LCH16_RS04300	COG1846	Transcriptional regulator
LCH16_RS04305	COG0392	lysyltransferase activity
LCH16_RS04305	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LCH16_RS04310	COG0384	phenazine biosynthesis protein PhzF
LCH16_RS04315	COG0778	Nitroreductase
LCH16_RS04330	COG1090	epimerase
LCH16_RS04350	COG2814	Major facilitator Superfamily
LCH16_RS04360	COG3591	Belongs to the peptidase S1B family
LCH16_RS04375	COG3103	Sh3 type 3 domain protein
LCH16_RS04380	COG5658	integral membrane protein
LCH16_RS04385	COG0596	Alpha beta hydrolase
LCH16_RS04390	COG0463	Glycosyl transferase, family 2
LCH16_RS04395	COG4485	Bacterial membrane protein, YfhO
LCH16_RS04400	COG1988	membrane-bound metal-dependent
LCH16_RS04405	COG1194	a g-specific adenine glycosylase
LCH16_RS04415	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS04435	COG1132	(ABC) transporter
LCH16_RS04440	COG4129	membrane
LCH16_RS04450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LCH16_RS04455	COG0735	belongs to the Fur family
LCH16_RS04575	COG3340	Belongs to the peptidase S51 family
LCH16_RS04585	COG0277	FAD linked oxidase domain protein
LCH16_RS04595	COG0747	negative chemotaxis
LCH16_RS04600	COG0601	transmembrane transport
LCH16_RS04605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCH16_RS04610	COG0444	Belongs to the ABC transporter superfamily
LCH16_RS04615	COG4608	Belongs to the ABC transporter superfamily
LCH16_RS04620	COG0753	catalase activity
LCH16_RS04630	COG1116	anion transmembrane transporter activity
LCH16_RS04635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LCH16_RS04640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCH16_RS04660	COG1476	TRANSCRIPTIONal
LCH16_RS04670	COG3382	B3 4 domain protein
LCH16_RS04675	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LCH16_RS04685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LCH16_RS04690	COG0789	Transcriptional regulator
LCH16_RS04695	COG1664	Polymer-forming cytoskeletal
LCH16_RS04700	COG1664	Polymer-forming cytoskeletal
LCH16_RS04705	COG2766	serine protein kinase
LCH16_RS04715	COG1846	Transcriptional regulator
LCH16_RS04720	COG1566	PFAM secretion protein HlyD family protein
LCH16_RS04725	COG2814	Major facilitator Superfamily
LCH16_RS04730	COG0655	NAD(P)H dehydrogenase (quinone) activity
LCH16_RS04745	COG1725	Transcriptional regulator
LCH16_RS04750	COG1131	(ABC) transporter
LCH16_RS04755	COG1131	(ABC) transporter
LCH16_RS04760	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LCH16_RS04765	COG1278	Cold shock
LCH16_RS04770	COG1464	Belongs to the NlpA lipoprotein family
LCH16_RS04775	COG3706	GGDEF domain
LCH16_RS04780	COG1823	symporter activity
LCH16_RS04800	COG5577	PFAM Coat F domain
LCH16_RS04805	COG0737	Belongs to the 5'-nucleotidase family
LCH16_RS04805	COG1525	nuclease
LCH16_RS04805	COG4085	toxin activity
LCH16_RS04810	COG3764	Sortase (surface protein transpeptidase)
LCH16_RS04815	COG0564	pseudouridine synthase activity
LCH16_RS04825	COG0517	IMP dehydrogenase activity
LCH16_RS04830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCH16_RS04835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LCH16_RS04835	COG3153	acetyltransferase
LCH16_RS04845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LCH16_RS04850	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LCH16_RS04855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCH16_RS04865	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LCH16_RS04870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCH16_RS04880	COG2197	response regulator
LCH16_RS04885	COG0431	NADPH-dependent FMN reductase
LCH16_RS04900	COG0791	NLP P60 protein
LCH16_RS04900	COG1388	LysM domain
LCH16_RS04905	COG1959	2 iron, 2 sulfur cluster binding
LCH16_RS04915	COG2719	SpoVR family
LCH16_RS04920	COG1785	Belongs to the alkaline phosphatase family
LCH16_RS04925	COG0791	NLP P60 protein
LCH16_RS04925	COG1388	LysM domain
LCH16_RS04930	COG0583	DNA-binding transcription factor activity
LCH16_RS04935	COG0372	Belongs to the citrate synthase family
LCH16_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS04945	COG0531	amino acid
LCH16_RS04950	COG0733	neurotransmitter:sodium symporter activity
LCH16_RS04965	COG1595	DNA-templated transcription, initiation
LCH16_RS04970	COG0204	Acyl-transferase
LCH16_RS04975	COG1253	flavin adenine dinucleotide binding
LCH16_RS04980	COG0789	Transcriptional regulator
LCH16_RS04985	COG0436	Aminotransferase
LCH16_RS04990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LCH16_RS04995	COG1253	flavin adenine dinucleotide binding
LCH16_RS05000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCH16_RS05005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCH16_RS05010	COG0584	glycerophosphoryl diester phosphodiesterase
LCH16_RS05020	COG0668	transmembrane transport
LCH16_RS05025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LCH16_RS05030	COG0726	polysaccharide deacetylase
LCH16_RS05035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCH16_RS05040	COG3226	Transcriptional regulator
LCH16_RS05050	COG0589	response to stress
LCH16_RS05055	COG1132	(ABC) transporter
LCH16_RS05060	COG1132	(ABC) transporter
LCH16_RS05065	COG0702	epimerase
LCH16_RS05085	COG0189	ligase activity
LCH16_RS05090	COG0189	ligase activity
LCH16_RS05105	COG4335	DNA alkylation repair
LCH16_RS05110	COG0561	phosphatase activity
LCH16_RS05115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCH16_RS05125	COG0475	glutathione-regulated potassium exporter activity
LCH16_RS05130	COG0490	domain, Protein
LCH16_RS05140	COG1024	Enoyl-CoA hydratase
LCH16_RS05150	COG4152	abc transporter atp-binding protein
LCH16_RS05155	COG1668	transmembrane transport
LCH16_RS05160	COG0420	3'-5' exonuclease activity
LCH16_RS05165	COG4717	serine-type aminopeptidase activity
LCH16_RS05180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCH16_RS05215	COG4980	gas vesicle protein
LCH16_RS05230	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LCH16_RS05235	COG0537	adenosine 5'-monophosphoramidase activity
LCH16_RS05240	COG1131	(ABC) transporter
LCH16_RS05245	COG4473	ABC transporter
LCH16_RS05255	COG1473	amidohydrolase
LCH16_RS05260	COG3069	C4-dicarboxylate transmembrane transporter activity
LCH16_RS05265	COG2329	Antibiotic biosynthesis monooxygenase
LCH16_RS05270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCH16_RS05280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LCH16_RS05285	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LCH16_RS05290	COG1309	transcriptional regulator
LCH16_RS05295	COG1511	domain protein
LCH16_RS05300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCH16_RS05310	COG1363	Peptidase, m42
LCH16_RS05315	COG1301	dicarboxylic acid transport
LCH16_RS05325	COG1234	tRNA 3'-trailer cleavage
LCH16_RS05330	COG0095	Lipoate-protein ligase
LCH16_RS05335	COG0702	epimerase
LCH16_RS05340	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS05350	COG0501	Belongs to the peptidase M48B family
LCH16_RS05355	COG1404	Belongs to the peptidase S8 family
LCH16_RS05360	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LCH16_RS05365	COG0406	alpha-ribazole phosphatase activity
LCH16_RS05370	COG0183	Belongs to the thiolase family
LCH16_RS05375	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS05380	COG1268	BioY protein
LCH16_RS05385	COG0840	transmembrane signaling receptor activity
LCH16_RS05390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCH16_RS05390	COG0723	plastoquinol--plastocyanin reductase activity
LCH16_RS05395	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS05405	COG4903	ComK protein
LCH16_RS05415	COG5646	InterPro IPR014922
LCH16_RS05440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCH16_RS05455	COG0398	Pfam SNARE associated Golgi protein
LCH16_RS05460	COG0681	Belongs to the peptidase S26 family
LCH16_RS05465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LCH16_RS05470	COG1846	Transcriptional regulator
LCH16_RS05475	COG3180	Ammonia monooxygenase
LCH16_RS05480	COG2814	Major facilitator Superfamily
LCH16_RS05490	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LCH16_RS05495	COG2323	membrane
LCH16_RS05510	COG0420	3'-5' exonuclease activity
LCH16_RS05515	COG0419	ATPase involved in DNA repair
LCH16_RS05520	COG1403	HNH endonuclease
LCH16_RS05560	COG0179	Fumarylacetoacetate (FAA) hydrolase
LCH16_RS05580	COG0367	asparagine synthase
LCH16_RS05585	COG1562	ergosterol biosynthetic process
LCH16_RS05590	COG0534	Mate efflux family protein
LCH16_RS05595	COG1917	Cupin 2, conserved barrel domain protein
LCH16_RS05595	COG2207	Transcriptional regulator
LCH16_RS05600	COG2318	DinB family
LCH16_RS05605	COG1279	arginine transmembrane transporter activity
LCH16_RS05610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCH16_RS05615	COG1357	PFAM Pentapeptide repeats (8 copies)
LCH16_RS05620	COG2153	protein acetylation
LCH16_RS05625	COG0646	methionine synthase
LCH16_RS05625	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LCH16_RS05635	COG2996	Protein conserved in bacteria
LCH16_RS05640	COG1744	ABC transporter substrate-binding protein PnrA-like
LCH16_RS05645	COG0840	transmembrane signaling receptor activity
LCH16_RS05650	COG2124	cytochrome p450
LCH16_RS05660	COG1307	EDD domain protein, DegV family
LCH16_RS05665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCH16_RS05685	COG0561	phosphatase activity
LCH16_RS05690	COG1073	alpha beta
LCH16_RS05695	COG2151	metal-sulfur cluster biosynthetic enzyme
LCH16_RS05735	COG0277	FAD linked oxidase domain protein
LCH16_RS05740	COG2271	Major facilitator Superfamily
LCH16_RS05750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LCH16_RS05760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LCH16_RS05765	COG0505	Belongs to the CarA family
LCH16_RS05770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LCH16_RS05775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LCH16_RS05790	COG2267	carboxylic ester hydrolase activity
LCH16_RS05800	COG1744	ABC transporter substrate-binding protein PnrA-like
LCH16_RS05815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCH16_RS05820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LCH16_RS05825	COG5504	Zn-dependent protease
LCH16_RS05830	COG0444	Belongs to the ABC transporter superfamily
LCH16_RS05835	COG4608	Belongs to the ABC transporter superfamily
LCH16_RS05845	COG0601	transmembrane transport
LCH16_RS05850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCH16_RS05860	COG0180	Tryptophanyl-tRNA synthetase
LCH16_RS05865	COG4166	transmembrane transport
LCH16_RS05870	COG0601	transmembrane transport
LCH16_RS05875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCH16_RS05880	COG0444	Belongs to the ABC transporter superfamily
LCH16_RS05885	COG4608	Belongs to the ABC transporter superfamily
LCH16_RS05895	COG0456	acetyltransferase
LCH16_RS05900	COG1393	Belongs to the ArsC family
LCH16_RS05905	COG0861	Integral membrane protein TerC family
LCH16_RS05910	COG4862	establishment of competence for transformation
LCH16_RS05915	COG4469	Competence protein
LCH16_RS05920	COG1164	Oligoendopeptidase f
LCH16_RS05930	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LCH16_RS05935	COG2346	COG2346, Truncated hemoglobins
LCH16_RS05940	COG0741	lytic transglycosylase activity
LCH16_RS05945	COG4116	CYTH
LCH16_RS05955	COG2357	RelA SpoT domain protein
LCH16_RS05960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LCH16_RS05965	COG0564	pseudouridine synthase activity
LCH16_RS05975	COG0475	glutathione-regulated potassium exporter activity
LCH16_RS05975	COG0569	domain protein
LCH16_RS05980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LCH16_RS05985	COG0352	thiamine-phosphate diphosphorylase activity
LCH16_RS05990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCH16_RS05995	COG2104	thiamine diphosphate biosynthetic process
LCH16_RS06005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LCH16_RS06010	COG0351	phosphomethylpyrimidine kinase
LCH16_RS06015	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LCH16_RS06070	COG0210	DNA helicase
LCH16_RS06090	COG1131	(ABC) transporter
LCH16_RS06100	COG2153	protein acetylation
LCH16_RS06110	COG2382	esterase
LCH16_RS06115	COG0626	cystathionine gamma-synthase activity
LCH16_RS06120	COG0626	cystathionine gamma-synthase activity
LCH16_RS06130	COG0582	viral genome integration into host DNA
LCH16_RS06135	COG2856	Zn peptidase
LCH16_RS06190	COG3935	DnaD domain protein
LCH16_RS06195	COG1484	DNA-dependent DNA replication
LCH16_RS06260	COG1595	DNA-templated transcription, initiation
LCH16_RS06285	COG5484	DNA packaging
LCH16_RS06400	COG4824	toxin secretion phage lysis holin
LCH16_RS06415	COG5444	nuclease activity
LCH16_RS06470	COG0537	adenosine 5'-monophosphoramidase activity
LCH16_RS06475	COG0135	phosphoribosylanthranilate isomerase activity
LCH16_RS06490	COG2367	Beta-lactamase
LCH16_RS06495	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LCH16_RS06500	COG0477	Major facilitator Superfamily
LCH16_RS06505	COG1846	Transcriptional regulator
LCH16_RS06515	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LCH16_RS06520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCH16_RS06525	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LCH16_RS06530	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCH16_RS06530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCH16_RS06535	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCH16_RS06560	COG1285	pathogenesis
LCH16_RS06575	COG2205	protein histidine kinase activity
LCH16_RS06585	COG3383	formate dehydrogenase (NAD+) activity
LCH16_RS06590	COG2427	Protein of unknown function (DUF1641)
LCH16_RS06595	COG2124	cytochrome p450
LCH16_RS06600	COG1819	glycosyl
LCH16_RS06610	COG1587	Uroporphyrinogen-III synthase
LCH16_RS06615	COG0390	transport system, permease component
LCH16_RS06620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCH16_RS06625	COG0697	spore germination
LCH16_RS06630	COG4297	protein containing double-stranded beta helix domain
LCH16_RS06640	COG1252	NADH dehydrogenase
LCH16_RS06650	COG2211	Major facilitator Superfamily
LCH16_RS06655	COG1609	Transcriptional regulator
LCH16_RS06660	COG0246	Mannitol dehydrogenase
LCH16_RS06665	COG2721	sulfolactate sulfo-lyase activity
LCH16_RS06670	COG0745	RESPONSE REGULATOR receiver
LCH16_RS06675	COG2205	protein histidine kinase activity
LCH16_RS06675	COG2770	Histidine kinase
LCH16_RS06680	COG1121	(ABC) transporter
LCH16_RS06695	COG0730	response to heat
LCH16_RS06700	COG2318	DinB family
LCH16_RS06705	COG0457	Tetratricopeptide repeat
LCH16_RS06715	COG5632	N-Acetylmuramoyl-L-alanine amidase
LCH16_RS06715	COG3409	Peptidoglycan-binding domain 1 protein
LCH16_RS06715	COG1388	LysM domain
LCH16_RS06725	COG4195	phage-related replication protein
LCH16_RS06730	COG3546	catalase activity
LCH16_RS06735	COG2856	Zn peptidase
LCH16_RS06740	COG1396	sequence-specific DNA binding
LCH16_RS06750	COG1522	sequence-specific DNA binding
LCH16_RS06755	COG1484	DNA-dependent DNA replication
LCH16_RS06775	COG1595	DNA-templated transcription, initiation
LCH16_RS06780	COG3728	DNA packaging
LCH16_RS06780	COG5484	DNA packaging
LCH16_RS06785	COG1783	phage Terminase large subunit
LCH16_RS06790	COG5518	Phage portal protein
LCH16_RS06795	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LCH16_RS06800	COG4653	Phage capsid family
LCH16_RS06850	COG3953	SLT domain
LCH16_RS06850	COG5412	phage tail tape measure protein
LCH16_RS06850	COG3953	SLT domain
LCH16_RS06850	COG5412	phage tail tape measure protein
LCH16_RS06855	COG1652	LysM domain
LCH16_RS06860	COG4193	domain, Protein
LCH16_RS06870	COG3628	GPW Gp25 family protein
LCH16_RS06875	COG3299	homolog of phage Mu protein gp47
LCH16_RS06880	COG3778	Protein conserved in bacteria
LCH16_RS06920	COG5632	N-Acetylmuramoyl-L-alanine amidase
LCH16_RS06920	COG3409	Peptidoglycan-binding domain 1 protein
LCH16_RS06940	COG0306	phosphate transporter
LCH16_RS06945	COG1392	Phosphate transport regulator
LCH16_RS06950	COG0531	amino acid
LCH16_RS06955	COG0346	lactoylglutathione lyase activity
LCH16_RS06960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LCH16_RS06965	COG0463	Glycosyl transferase, family 2
LCH16_RS06975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCH16_RS06980	COG0477	Major facilitator Superfamily
LCH16_RS06985	COG2362	D-Aminopeptidase
LCH16_RS06990	COG0601	transmembrane transport
LCH16_RS06995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCH16_RS07000	COG0444	Belongs to the ABC transporter superfamily
LCH16_RS07005	COG4166	transmembrane transport
LCH16_RS07010	COG1619	proteins homologs of microcin C7 resistance protein MccF
LCH16_RS07015	COG4948	Mandelate Racemase Muconate Lactonizing
LCH16_RS07020	COG0791	NLP P60 protein
LCH16_RS07025	COG4608	Belongs to the ABC transporter superfamily
LCH16_RS07030	COG2706	6-phosphogluconolactonase activity
LCH16_RS07035	COG1834	amidinotransferase
LCH16_RS07040	COG1607	acyl-coa hydrolase
LCH16_RS07045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCH16_RS07050	COG2076	Multidrug Resistance protein
LCH16_RS07055	COG2076	Multidrug Resistance protein
LCH16_RS07060	COG0788	formyltetrahydrofolate deformylase activity
LCH16_RS07065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LCH16_RS07075	COG1764	response to oxidative stress
LCH16_RS07080	COG1846	Transcriptional regulator
LCH16_RS07085	COG1764	response to oxidative stress
LCH16_RS07100	COG0463	Glycosyl transferase, family 2
LCH16_RS07100	COG0457	Tetratricopeptide repeat
LCH16_RS07110	COG2814	Major facilitator Superfamily
LCH16_RS07115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCH16_RS07125	COG1404	Belongs to the peptidase S8 family
LCH16_RS07130	COG1366	Belongs to the anti-sigma-factor antagonist family
LCH16_RS07135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCH16_RS07140	COG1122	ATPase activity
LCH16_RS07145	COG4721	ABC-type cobalt transport system, permease component
LCH16_RS07150	COG1388	LysM domain
LCH16_RS07150	COG3858	chitin binding
LCH16_RS07160	COG2239	Acts as a magnesium transporter
LCH16_RS07165	COG0789	Transcriptional regulator
LCH16_RS07180	COG1846	Transcriptional regulator
LCH16_RS07185	COG0726	polysaccharide deacetylase
LCH16_RS07190	COG1793	dna ligase
LCH16_RS07190	COG3285	dna ligase
LCH16_RS07195	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LCH16_RS07200	COG0586	Pfam SNARE associated Golgi protein
LCH16_RS07210	COG1191	sigma factor activity
LCH16_RS07235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LCH16_RS07240	COG2323	membrane
LCH16_RS07250	COG3594	Acyltransferase
LCH16_RS07255	COG5002	protein histidine kinase activity
LCH16_RS07260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LCH16_RS07280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LCH16_RS07285	COG0436	Aminotransferase
LCH16_RS07315	COG3852	Histidine kinase
LCH16_RS07320	COG1846	Transcriptional regulator
LCH16_RS07325	COG1360	Flagellar Motor Protein
LCH16_RS07330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LCH16_RS07335	COG0542	response to heat
LCH16_RS07340	COG3949	Membrane
LCH16_RS07355	COG0720	synthase
LCH16_RS07360	COG0602	queuosine metabolic process
LCH16_RS07370	COG1733	regulation of RNA biosynthetic process
LCH16_RS07375	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS07395	COG4873	Protein conserved in bacteria
LCH16_RS07405	COG3773	Cell wall hydrolase
LCH16_RS07410	COG2244	polysaccharide biosynthetic process
LCH16_RS07415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCH16_RS07420	COG2217	Heavy metal translocating P-type atpase
LCH16_RS07425	COG0006	proline dipeptidase activity
LCH16_RS07430	COG1609	Transcriptional regulator
LCH16_RS07435	COG3711	transcriptional antiterminator
LCH16_RS07440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCH16_RS07440	COG2190	(PTS) system
LCH16_RS07440	COG1263	PTS System
LCH16_RS07445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCH16_RS07450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCH16_RS07460	COG1533	DNA photolyase activity
LCH16_RS07465	COG0840	transmembrane signaling receptor activity
LCH16_RS07470	COG2084	Dehydrogenase
LCH16_RS07475	COG2340	Cysteine-rich secretory protein family
LCH16_RS07480	COG0768	penicillin binding
LCH16_RS07485	COG4191	Histidine kinase
LCH16_RS07490	COG0436	Aminotransferase
LCH16_RS07500	COG0784	Response regulator, receiver
LCH16_RS07500	COG0835	chemotaxis
LCH16_RS07510	COG2814	Major facilitator Superfamily
LCH16_RS07515	COG1376	ErfK ybiS ycfS ynhG family protein
LCH16_RS07520	COG1408	metallophosphoesterase
LCH16_RS07525	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS07535	COG2200	EAL domain
LCH16_RS07540	COG4703	Protein of unknown function (DUF1797)
LCH16_RS07545	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LCH16_RS07555	COG0517	IMP dehydrogenase activity
LCH16_RS07560	COG0583	DNA-binding transcription factor activity
LCH16_RS07565	COG0716	FMN binding
LCH16_RS07575	COG0716	FMN binding
LCH16_RS07600	COG0668	transmembrane transport
LCH16_RS07605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCH16_RS07625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LCH16_RS07630	COG0303	'Molybdopterin
LCH16_RS07635	COG1763	Mo-molybdopterin cofactor biosynthetic process
LCH16_RS07640	COG0314	molybdopterin synthase activity
LCH16_RS07645	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LCH16_RS07655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LCH16_RS07660	COG1136	(ABC) transporter
LCH16_RS07665	COG0577	efflux transmembrane transporter activity
LCH16_RS07670	COG1349	DNA-binding transcription factor activity
LCH16_RS07675	COG1105	Belongs to the carbohydrate kinase PfkB family
LCH16_RS07680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCH16_RS07680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCH16_RS07680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCH16_RS07685	COG0681	Belongs to the peptidase S26 family
LCH16_RS07695	COG0488	(ABC) transporter
LCH16_RS07700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LCH16_RS07705	COG2309	aminopeptidase activity
LCH16_RS07715	COG1077	Cell shape determining protein MreB Mrl
LCH16_RS07720	COG2002	toxin-antitoxin pair type II binding
LCH16_RS07725	COG3852	Histidine kinase
LCH16_RS07730	COG2105	PFAM AIG2 family protein
LCH16_RS07730	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LCH16_RS07735	COG0569	domain protein
LCH16_RS07745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCH16_RS07755	COG0561	phosphatase activity
LCH16_RS07760	COG0242	peptide deformylase activity
LCH16_RS07770	COG0497	DNA recombination
LCH16_RS07780	COG4221	oxidoreductase activity
LCH16_RS07780	COG3321	synthase
LCH16_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS07780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS07785	COG0300	oxidoreductase activity
LCH16_RS07785	COG3321	synthase
LCH16_RS07785	COG4221	oxidoreductase activity
LCH16_RS07785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS07790	COG4221	oxidoreductase activity
LCH16_RS07790	COG3321	synthase
LCH16_RS07790	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS07790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS07795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS07795	COG0300	oxidoreductase activity
LCH16_RS07795	COG3321	synthase
LCH16_RS07795	COG4221	oxidoreductase activity
LCH16_RS07800	COG4221	oxidoreductase activity
LCH16_RS07800	COG3321	synthase
LCH16_RS07800	COG0300	oxidoreductase activity
LCH16_RS07800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS07805	COG0300	oxidoreductase activity
LCH16_RS07805	COG3321	synthase
LCH16_RS07805	COG4221	oxidoreductase activity
LCH16_RS07805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS07810	COG3321	synthase
LCH16_RS07810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS07810	COG4221	oxidoreductase activity
LCH16_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS07815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCH16_RS07820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LCH16_RS07825	COG0022	dehydrogenase e1 component
LCH16_RS07830	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCH16_RS07835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCH16_RS07840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCH16_RS07855	COG1982	Orn Lys Arg decarboxylase major
LCH16_RS07875	COG0483	inositol monophosphate 1-phosphatase activity
LCH16_RS07885	COG3227	Zinc metalloprotease (Elastase)
LCH16_RS07900	COG1595	DNA-templated transcription, initiation
LCH16_RS07920	COG1217	gtp-binding protein TYPA
LCH16_RS07930	COG4896	Protein conserved in bacteria
LCH16_RS07940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LCH16_RS07945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LCH16_RS07950	COG2066	Belongs to the glutaminase family
LCH16_RS07960	COG0772	Belongs to the SEDS family
LCH16_RS07965	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LCH16_RS07980	COG2010	Cytochrome c
LCH16_RS07980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LCH16_RS07985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LCH16_RS07990	COG1845	cytochrome c oxidase, subunit III
LCH16_RS07995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LCH16_RS08000	COG3336	cytochrome c oxidase
LCH16_RS08015	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LCH16_RS08020	COG2340	Cysteine-rich secretory protein family
LCH16_RS08035	COG3679	Belongs to the UPF0342 family
LCH16_RS08045	COG0742	ribosomal rna small subunit methyltransferase
LCH16_RS08055	COG3314	Sporulation integral membrane protein YlbJ
LCH16_RS08060	COG1752	Esterase of the alpha-beta hydrolase superfamily
LCH16_RS08065	COG3480	Lon protease (S16) C-terminal proteolytic domain
LCH16_RS08075	COG1399	metal-binding, possibly nucleic acid-binding protein
LCH16_RS08095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LCH16_RS08115	COG4839	cell division protein FtsL
LCH16_RS08120	COG0768	penicillin binding
LCH16_RS08125	COG0768	penicillin binding
LCH16_RS08145	COG0772	Belongs to the SEDS family
LCH16_RS08160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LCH16_RS08165	COG0849	cell division
LCH16_RS08170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LCH16_RS08175	COG1404	Belongs to the peptidase S8 family
LCH16_RS08175	COG4412	M6 family metalloprotease domain protein
LCH16_RS08185	COG1191	sigma factor activity
LCH16_RS08190	COG1191	sigma factor activity
LCH16_RS08195	COG1119	ATPase activity
LCH16_RS08200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCH16_RS08205	COG1873	PFAM PRC-barrel domain
LCH16_RS08210	COG1496	oxidoreductase activity
LCH16_RS08215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LCH16_RS08225	COG0762	integral membrane protein
LCH16_RS08230	COG2302	S4 RNA-binding domain
LCH16_RS08235	COG3599	regulation of cell shape
LCH16_RS08240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LCH16_RS08245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LCH16_RS08255	COG0564	pseudouridine synthase activity
LCH16_RS08265	COG2233	PERMEase
LCH16_RS08275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LCH16_RS08280	COG0505	Belongs to the CarA family
LCH16_RS08285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LCH16_RS08300	COG0284	orotidine-5'-phosphate decarboxylase activity
LCH16_RS08305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCH16_RS08315	COG0306	phosphate transporter
LCH16_RS08330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LCH16_RS08335	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LCH16_RS08340	COG1648	precorrin-2 dehydrogenase activity
LCH16_RS08350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCH16_RS08355	COG1561	YicC-like family, N-terminal region
LCH16_RS08365	COG0194	GDP metabolic process
LCH16_RS08375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCH16_RS08380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCH16_RS08385	COG0242	peptide deformylase activity
LCH16_RS08395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCH16_RS08395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCH16_RS08405	COG0631	protein serine/threonine phosphatase activity
LCH16_RS08410	COG0515	serine threonine protein kinase
LCH16_RS08410	COG2815	serine threonine protein kinase
LCH16_RS08420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCH16_RS08425	COG1564	THIamine pyrophosphokinase
LCH16_RS08440	COG1302	Protein conserved in bacteria
LCH16_RS08445	COG1461	Dihydroxyacetone kinase
LCH16_RS08450	COG1760	l-serine dehydratase
LCH16_RS08455	COG1760	l-serine dehydratase
LCH16_RS08460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LCH16_RS08475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LCH16_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS08495	COG1196	nuclear chromosome segregation
LCH16_RS08500	COG0552	protein localization to endoplasmic reticulum
LCH16_RS08515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCH16_RS08525	COG1837	Belongs to the UPF0109 family
LCH16_RS08550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LCH16_RS08565	COG2257	FlhB HrpN YscU SpaS Family
LCH16_RS08575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LCH16_RS08580	COG0758	DNA mediated transformation
LCH16_RS08585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCH16_RS08595	COG4974	Belongs to the 'phage' integrase family
LCH16_RS08615	COG1815	bacterial-type flagellum-dependent cell motility
LCH16_RS08620	COG1558	bacterial-type flagellum-dependent cell motility
LCH16_RS08625	COG1677	Flagellar hook-basal body complex protein FliE
LCH16_RS08630	COG1766	The M ring may be actively involved in energy transduction
LCH16_RS08635	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LCH16_RS08640	COG1317	bacterial-type flagellum organization
LCH16_RS08645	COG1157	protein secretion by the type III secretion system
LCH16_RS08650	COG2882	bacterial-type flagellum organization
LCH16_RS08655	COG3334	PFAM MgtE intracellular
LCH16_RS08660	COG3144	bacterial-type flagellum assembly
LCH16_RS08665	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LCH16_RS08670	COG4786	Flagellar basal body rod
LCH16_RS08675	COG1582	Flagellar protein (FlbD)
LCH16_RS08680	COG1580	Controls the rotational direction of flagella during chemotaxis
LCH16_RS08685	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LCH16_RS08690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LCH16_RS08690	COG1776	CheC inhibitor of MCP methylation
LCH16_RS08695	COG2201	protein-glutamate methylesterase activity
LCH16_RS08700	COG3190	flagellar
LCH16_RS08705	COG1338	Plays a role in the flagellum-specific transport system
LCH16_RS08710	COG1987	bacterial-type flagellum assembly
LCH16_RS08715	COG1684	flagellar biosynthetic protein fliR
LCH16_RS08720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LCH16_RS08725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LCH16_RS08730	COG1419	protein localization to endoplasmic reticulum
LCH16_RS08735	COG0455	bacterial-type flagellum organization
LCH16_RS08740	COG2201	protein-glutamate methylesterase activity
LCH16_RS08745	COG0643	Histidine kinase
LCH16_RS08745	COG2198	Histidine kinase
LCH16_RS08750	COG0835	chemotaxis
LCH16_RS08755	COG1776	CheC inhibitor of MCP methylation
LCH16_RS08765	COG1191	sigma factor activity
LCH16_RS08795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LCH16_RS08800	COG4589	Belongs to the CDS family
LCH16_RS08810	COG0750	zinc metalloprotease
LCH16_RS08830	COG0195	Participates in both transcription termination and antitermination
LCH16_RS08835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LCH16_RS08840	COG1358	cellular component organization or biogenesis
LCH16_RS08850	COG1550	Protein conserved in bacteria
LCH16_RS08865	COG0196	riboflavin kinase activity
LCH16_RS08880	COG0726	polysaccharide deacetylase
LCH16_RS08885	COG0612	Peptidase, M16
LCH16_RS08890	COG1873	PFAM PRC-barrel domain
LCH16_RS08895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCH16_RS08900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCH16_RS08905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LCH16_RS08910	COG0527	aspartate kinase activity
LCH16_RS08920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCH16_RS08925	COG0740	serine-type endopeptidase activity
LCH16_RS08935	COG4980	gas vesicle protein
LCH16_RS08935	COG1674	ftsk spoiiie
LCH16_RS08940	COG2188	Transcriptional regulator
LCH16_RS08945	COG2814	Major facilitator Superfamily
LCH16_RS08950	COG1846	Transcriptional regulator
LCH16_RS08955	COG1033	growth of symbiont in host cell
LCH16_RS08955	COG2409	Drug exporters of the RND superfamily
LCH16_RS08960	COG0612	Peptidase, M16
LCH16_RS08965	COG0612	Peptidase, M16
LCH16_RS08970	COG0300	oxidoreductase activity
LCH16_RS08985	COG1426	Protein conserved in bacteria
LCH16_RS08990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LCH16_RS09005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCH16_RS09015	COG1692	metallophosphoesterase
LCH16_RS09020	COG2359	stage V sporulation protein S
LCH16_RS09040	COG4550	Control of competence regulator ComK, YlbF/YmcA
LCH16_RS09060	COG0582	viral genome integration into host DNA
LCH16_RS09110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS09115	COG3425	synthase
LCH16_RS09120	COG1024	Enoyl-CoA hydratase
LCH16_RS09125	COG1024	Enoyl-CoA hydratase
LCH16_RS09130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS09130	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS09130	COG0300	oxidoreductase activity
LCH16_RS09130	COG3321	synthase
LCH16_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS09135	COG4221	oxidoreductase activity
LCH16_RS09135	COG3321	synthase
LCH16_RS09135	COG0300	oxidoreductase activity
LCH16_RS09135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS09140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS09140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCH16_RS09140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS09140	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS09140	COG3321	synthase
LCH16_RS09140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS09140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCH16_RS09140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS09140	COG3321	synthase
LCH16_RS09140	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS09145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS09145	COG3321	synthase
LCH16_RS09145	COG4221	oxidoreductase activity
LCH16_RS09150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS09150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LCH16_RS09150	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LCH16_RS09150	COG3321	synthase
LCH16_RS09155	COG2124	cytochrome p450
LCH16_RS09160	COG3209	COG3209 Rhs family protein
LCH16_RS09165	COG3619	membrane
LCH16_RS09175	COG1404	Belongs to the peptidase S8 family
LCH16_RS09185	COG4195	phage-related replication protein
LCH16_RS09190	COG1764	response to oxidative stress
LCH16_RS09200	COG2076	Multidrug Resistance protein
LCH16_RS09240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCH16_RS09245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCH16_RS09250	COG4112	unkown
LCH16_RS09255	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCH16_RS09260	COG0464	growth
LCH16_RS09265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCH16_RS09270	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LCH16_RS09275	COG0789	Transcriptional regulator
LCH16_RS09280	COG0174	glutamine synthetase
LCH16_RS09305	COG2211	Major facilitator Superfamily
LCH16_RS09310	COG3507	Belongs to the glycosyl hydrolase 43 family
LCH16_RS09325	COG1070	Carbohydrate kinase
LCH16_RS09330	COG0574	Belongs to the PEP-utilizing enzyme family
LCH16_RS09330	COG3848	Pyruvate phosphate dikinase
LCH16_RS09345	COG2318	DinB family
LCH16_RS09350	COG1064	alcohol dehydrogenase
LCH16_RS09365	COG0456	acetyltransferase
LCH16_RS09390	COG3397	chitin binding
LCH16_RS09400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCH16_RS09415	COG5434	Belongs to the glycosyl hydrolase 28 family
LCH16_RS09420	COG0756	dUTP diphosphatase activity
LCH16_RS09425	COG4195	phage-related replication protein
LCH16_RS09460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LCH16_RS09470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LCH16_RS09490	COG0785	Cytochrome C biogenesis protein
LCH16_RS09495	COG2201	protein-glutamate methylesterase activity
LCH16_RS09500	COG4846	Membrane protein involved in cytochrome C biogenesis
LCH16_RS09510	COG0071	Belongs to the small heat shock protein (HSP20) family
LCH16_RS09525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LCH16_RS09530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCH16_RS09550	COG0824	Thioesterase
LCH16_RS09560	COG4841	protein insertion into membrane
LCH16_RS09570	COG1832	CoA-binding protein
LCH16_RS09575	COG0187	DNA topoisomerase II activity
LCH16_RS09580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCH16_RS09590	COG1115	amino acid carrier protein
LCH16_RS09600	COG1063	alcohol dehydrogenase
LCH16_RS09605	COG0800	Aldolase
LCH16_RS09610	COG1312	Catalyzes the dehydration of D-mannonate
LCH16_RS09615	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS09620	COG1609	Transcriptional regulator
LCH16_RS09625	COG2271	Major facilitator Superfamily
LCH16_RS09665	COG2205	protein histidine kinase activity
LCH16_RS09670	COG0745	RESPONSE REGULATOR receiver
LCH16_RS09680	COG3507	Belongs to the glycosyl hydrolase 43 family
LCH16_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS09710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LCH16_RS09715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LCH16_RS09720	COG2610	gluconate transmembrane transporter activity
LCH16_RS09725	COG2124	cytochrome p450
LCH16_RS09745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LCH16_RS09755	COG2246	polysaccharide biosynthetic process
LCH16_RS09760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LCH16_RS09765	COG0586	Pfam SNARE associated Golgi protein
LCH16_RS09770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LCH16_RS09775	COG1024	Enoyl-CoA hydratase
LCH16_RS09780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LCH16_RS09785	COG0511	ligase activity, forming carbon-carbon bonds
LCH16_RS09790	COG0439	Biotin carboxylase
LCH16_RS09795	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS09800	COG1960	acyl-CoA dehydrogenase activity
LCH16_RS09805	COG1649	PFAM Uncharacterised BCR, COG1649
LCH16_RS09815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS09815	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LCH16_RS09820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS09825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS09830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS09835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS09840	COG2027	D-alanyl-D-alanine carboxypeptidase
LCH16_RS09845	COG2017	converts alpha-aldose to the beta-anomer
LCH16_RS09850	COG0534	Mate efflux family protein
LCH16_RS09885	COG5632	N-Acetylmuramoyl-L-alanine amidase
LCH16_RS09885	COG3409	Peptidoglycan-binding domain 1 protein
LCH16_RS09915	COG5434	Belongs to the glycosyl hydrolase 28 family
LCH16_RS09920	COG1388	LysM domain
LCH16_RS09920	COG1705	Flagellar rod assembly protein muramidase FlgJ
LCH16_RS09995	COG1802	Transcriptional regulator
LCH16_RS09995	COG4626	Terminase
LCH16_RS10025	COG0582	viral genome integration into host DNA
LCH16_RS10030	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LCH16_RS10140	COG0582	viral genome integration into host DNA
LCH16_RS10145	COG0166	Belongs to the GPI family
LCH16_RS10150	COG0405	Gamma-glutamyltransferase
LCH16_RS10155	COG2814	Major facilitator Superfamily
LCH16_RS10160	COG0640	Transcriptional regulator
LCH16_RS10165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCH16_RS10175	COG0604	alcohol dehydrogenase
LCH16_RS10180	COG0493	'glutamate synthase
LCH16_RS10185	COG0067	glutamate synthase
LCH16_RS10185	COG0069	glutamate synthase activity
LCH16_RS10185	COG0070	glutamate synthase
LCH16_RS10190	COG0583	DNA-binding transcription factor activity
LCH16_RS10195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LCH16_RS10210	COG0300	oxidoreductase activity
LCH16_RS10215	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LCH16_RS10225	COG2814	Major facilitator Superfamily
LCH16_RS10235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LCH16_RS10240	COG0243	molybdopterin cofactor binding
LCH16_RS10270	COG5444	nuclease activity
LCH16_RS10275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCH16_RS10280	COG0662	Cupin 2, conserved barrel domain protein
LCH16_RS10280	COG2207	Transcriptional regulator
LCH16_RS10285	COG1309	transcriptional regulator
LCH16_RS10290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCH16_RS10300	COG0640	Transcriptional regulator
LCH16_RS10305	COG0741	lytic transglycosylase activity
LCH16_RS10310	COG2322	membrane
LCH16_RS10325	COG1619	proteins homologs of microcin C7 resistance protein MccF
LCH16_RS10335	COG1388	LysM domain
LCH16_RS10335	COG3584	3D domain protein
LCH16_RS10340	COG0514	ATP-dependent DNA helicase (RecQ)
LCH16_RS10350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LCH16_RS10355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LCH16_RS10370	COG0071	Belongs to the small heat shock protein (HSP20) family
LCH16_RS10400	COG1012	belongs to the aldehyde dehydrogenase family
LCH16_RS10405	COG1657	PFAM Prenyltransferase squalene oxidase
LCH16_RS10410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LCH16_RS10415	COG0733	neurotransmitter:sodium symporter activity
LCH16_RS10420	COG0385	Bile acid
LCH16_RS10425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCH16_RS10430	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCH16_RS10440	COG4548	von Willebrand factor, type A
LCH16_RS10445	COG0714	Associated with various cellular activities
LCH16_RS10450	COG2032	superoxide dismutase activity
LCH16_RS10455	COG0791	NLP P60 protein
LCH16_RS10455	COG1388	LysM domain
LCH16_RS10460	COG1819	glycosyl
LCH16_RS10465	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LCH16_RS10470	COG0534	Mate efflux family protein
LCH16_RS10475	COG1366	Belongs to the anti-sigma-factor antagonist family
LCH16_RS10480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LCH16_RS10485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LCH16_RS10495	COG2962	Rard protein
LCH16_RS10510	COG1942	4-Oxalocrotonate Tautomerase
LCH16_RS10520	COG1733	regulation of RNA biosynthetic process
LCH16_RS10525	COG0778	Nitroreductase
LCH16_RS10530	COG0400	carboxylic ester hydrolase activity
LCH16_RS10535	COG0346	lactoylglutathione lyase activity
LCH16_RS10545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCH16_RS10555	COG2723	6-phospho-beta-galactosidase activity
LCH16_RS10560	COG2188	Transcriptional regulator
LCH16_RS10565	COG0793	Belongs to the peptidase S41A family
LCH16_RS10565	COG3409	Peptidoglycan-binding domain 1 protein
LCH16_RS10570	COG2226	methyltransferase
LCH16_RS10580	COG1876	peptidase activity
LCH16_RS10600	COG0671	phosphoesterase, PA-phosphatase related
LCH16_RS10635	COG1509	lysine 2,3-aminomutase activity
LCH16_RS10640	COG0456	acetyltransferase
LCH16_RS10645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCH16_RS10650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LCH16_RS10655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LCH16_RS10660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LCH16_RS10665	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LCH16_RS10675	COG0456	acetyltransferase
LCH16_RS10680	COG0463	Glycosyl transferase, family 2
LCH16_RS10695	COG4641	Protein conserved in bacteria
LCH16_RS10705	COG1086	Polysaccharide biosynthesis protein
LCH16_RS10755	COG1388	LysM domain
LCH16_RS10760	COG0457	Tetratricopeptide repeat
LCH16_RS10780	COG5444	nuclease activity
LCH16_RS10785	COG4282	regulation of fungal-type cell wall biogenesis
LCH16_RS10790	COG1525	nuclease
LCH16_RS10795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LCH16_RS10815	COG1846	Transcriptional regulator
LCH16_RS10820	COG4698	Protein conserved in bacteria
LCH16_RS10825	COG2755	lipolytic protein G-D-S-L family
LCH16_RS10830	COG1999	signal sequence binding
LCH16_RS10840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LCH16_RS10845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LCH16_RS10850	COG1272	protein, Hemolysin III
LCH16_RS10860	COG0204	Acyl-transferase
LCH16_RS10865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LCH16_RS10880	COG2136	Putative SAM-dependent methyltransferase
LCH16_RS10880	COG2521	methyltransferase
LCH16_RS10895	COG1413	lyase activity
LCH16_RS10900	COG1418	mRNA catabolic process
LCH16_RS10905	COG0386	Belongs to the glutathione peroxidase family
LCH16_RS10915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LCH16_RS10925	COG1278	Cold shock
LCH16_RS10945	COG0328	RNA-DNA hybrid ribonuclease activity
LCH16_RS10950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LCH16_RS10955	COG0328	RNA-DNA hybrid ribonuclease activity
LCH16_RS10965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCH16_RS10980	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LCH16_RS10990	COG1755	Isoprenylcysteine carboxyl methyltransferase
LCH16_RS10995	COG3424	synthase
LCH16_RS11020	COG1335	isochorismatase
LCH16_RS11030	COG2233	PERMEase
LCH16_RS11040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LCH16_RS11045	COG1199	ATP-dependent helicase activity
LCH16_RS11060	COG0116	Belongs to the methyltransferase superfamily
LCH16_RS11090	COG3359	exonuclease
LCH16_RS11095	COG1111	helicase
LCH16_RS11095	COG1205	dead DEAH box helicase
LCH16_RS11100	COG2190	(PTS) system
LCH16_RS11105	COG0071	Belongs to the small heat shock protein (HSP20) family
LCH16_RS11145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCH16_RS11145	COG4499	WXG100 protein secretion system (Wss), protein YukC
LCH16_RS11160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCH16_RS11165	COG3935	DnaD domain protein
LCH16_RS11175	COG0436	Aminotransferase
LCH16_RS11180	COG5353	protein conserved in bacteria
LCH16_RS11190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LCH16_RS11190	COG1199	ATP-dependent helicase activity
LCH16_RS11220	COG0438	transferase activity, transferring glycosyl groups
LCH16_RS11225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LCH16_RS11240	COG1694	Mazg nucleotide pyrophosphohydrolase
LCH16_RS11245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCH16_RS11250	COG2140	Oxalate decarboxylase
LCH16_RS11260	COG4347	Protein of unknown function (DUF1405)
LCH16_RS11265	COG2010	Cytochrome c
LCH16_RS11265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LCH16_RS11270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LCH16_RS11275	COG0723	plastoquinol--plastocyanin reductase activity
LCH16_RS11290	COG0457	Tetratricopeptide repeat
LCH16_RS11300	COG0287	Prephenate dehydrogenase
LCH16_RS11335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LCH16_RS11340	COG4401	Chorismate mutase type I
LCH16_RS11355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LCH16_RS11360	COG0105	UTP biosynthetic process
LCH16_RS11365	COG0142	geranyltranstransferase activity
LCH16_RS11375	COG0142	geranyltranstransferase activity
LCH16_RS11390	COG0776	regulation of translation
LCH16_RS11395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LCH16_RS11435	COG0539	negative regulation of cytoplasmic translation
LCH16_RS11450	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LCH16_RS11455	COG2959	enzyme of heme biosynthesis
LCH16_RS11460	COG3773	Cell wall hydrolase
LCH16_RS11460	COG3409	Peptidoglycan-binding domain 1 protein
LCH16_RS11465	COG2339	peptidase activity
LCH16_RS11470	COG0492	ferredoxin-NADP+ reductase activity
LCH16_RS11475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LCH16_RS11480	COG4862	establishment of competence for transformation
LCH16_RS11485	COG1408	metallophosphoesterase
LCH16_RS11495	COG1388	LysM domain
LCH16_RS11500	COG1266	CAAX protease self-immunity
LCH16_RS11505	COG0514	ATP-dependent DNA helicase (RecQ)
LCH16_RS11510	COG4955	Helix-turn-helix domain
LCH16_RS11515	COG1141	Ferredoxin
LCH16_RS11520	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LCH16_RS11525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LCH16_RS11535	COG1595	DNA-templated transcription, initiation
LCH16_RS11540	COG5002	protein histidine kinase activity
LCH16_RS11545	COG0745	RESPONSE REGULATOR receiver
LCH16_RS11550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LCH16_RS11555	COG1333	cytochrome c biogenesis protein
LCH16_RS11560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCH16_RS11565	COG1187	pseudouridine synthase activity
LCH16_RS11570	COG0700	Nucleoside recognition
LCH16_RS11575	COG2715	membrane protein required for spore maturation
LCH16_RS11580	COG1686	Belongs to the peptidase S11 family
LCH16_RS11605	COG1547	Domain of unknown function (DUF309)
LCH16_RS11610	COG0456	acetyltransferase
LCH16_RS11625	COG0307	riboflavin synthase, alpha
LCH16_RS11630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LCH16_RS11630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LCH16_RS11640	COG0681	Belongs to the peptidase S26 family
LCH16_RS11650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LCH16_RS11655	COG4086	secreted protein
LCH16_RS11660	COG0019	diaminopimelate decarboxylase activity
LCH16_RS11665	COG0697	spore germination
LCH16_RS11680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCH16_RS11700	COG1191	sigma factor activity
LCH16_RS11710	COG1366	Belongs to the anti-sigma-factor antagonist family
LCH16_RS11715	COG1686	Belongs to the peptidase S11 family
LCH16_RS11720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LCH16_RS11725	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LCH16_RS11730	COG4974	Belongs to the 'phage' integrase family
LCH16_RS11740	COG0735	belongs to the Fur family
LCH16_RS11745	COG1300	Membrane
LCH16_RS11760	COG0281	malic enzyme
LCH16_RS11765	COG1757	Na H antiporter
LCH16_RS11770	COG1027	Aspartate ammonia-lyase
LCH16_RS11775	COG0252	asparaginase activity
LCH16_RS11780	COG1396	sequence-specific DNA binding
LCH16_RS11785	COG1379	DNA repair
LCH16_RS11790	COG0494	nUDIX hydrolase
LCH16_RS11800	COG0667	Aldo Keto reductase
LCH16_RS11810	COG1073	alpha beta
LCH16_RS11820	COG4918	Iron-sulphur cluster biosynthesis
LCH16_RS11825	COG0456	acetyltransferase
LCH16_RS11825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCH16_RS11830	COG2329	Antibiotic biosynthesis monooxygenase
LCH16_RS11835	COG0456	acetyltransferase
LCH16_RS11840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCH16_RS11855	COG0628	permease
LCH16_RS11865	COG0346	lactoylglutathione lyase activity
LCH16_RS11875	COG3048	D-serine ammonia-lyase activity
LCH16_RS11880	COG0300	oxidoreductase activity
LCH16_RS11885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCH16_RS11890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCH16_RS11895	COG1024	Enoyl-CoA hydratase
LCH16_RS11900	COG3425	synthase
LCH16_RS11905	COG2124	cytochrome p450
LCH16_RS11910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS11910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCH16_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS11910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS11910	COG3321	synthase
LCH16_RS11915	COG3321	synthase
LCH16_RS11915	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS11915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS11915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCH16_RS11915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS11920	COG0300	oxidoreductase activity
LCH16_RS11920	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS11920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS11920	COG3321	synthase
LCH16_RS11920	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS11925	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS11925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS11925	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS11925	COG0300	oxidoreductase activity
LCH16_RS11925	COG3321	synthase
LCH16_RS11930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS11930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS11930	COG3321	synthase
LCH16_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS11930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCH16_RS11935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS11935	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS11935	COG0300	oxidoreductase activity
LCH16_RS11935	COG3321	synthase
LCH16_RS11935	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS11940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCH16_RS11940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS11940	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS11940	COG3321	synthase
LCH16_RS11940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCH16_RS11945	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS11950	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS11965	COG2070	2-Nitropropane dioxygenase
LCH16_RS11965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LCH16_RS11970	COG0250	Participates in transcription elongation, termination and antitermination
LCH16_RS11990	COG0596	Alpha beta hydrolase
LCH16_RS12005	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LCH16_RS12010	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LCH16_RS12025	COG0706	membrane insertase activity
LCH16_RS12030	COG2195	Cleaves the N-terminal amino acid of tripeptides
LCH16_RS12035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LCH16_RS12040	COG0346	lactoylglutathione lyase activity
LCH16_RS12050	COG1376	ErfK ybiS ycfS ynhG family protein
LCH16_RS12055	COG4129	membrane
LCH16_RS12060	COG1126	abc transporter atp-binding protein
LCH16_RS12065	COG0765	amino acid transport
LCH16_RS12070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCH16_RS12080	COG1597	lipid kinase activity
LCH16_RS12085	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCH16_RS12090	COG0022	dehydrogenase e1 component
LCH16_RS12095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LCH16_RS12100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCH16_RS12105	COG3426	butyrate kinase activity
LCH16_RS12110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LCH16_RS12115	COG0280	phosphate acetyltransferase
LCH16_RS12120	COG3290	protein histidine kinase activity
LCH16_RS12120	COG3829	transcription factor binding
LCH16_RS12130	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LCH16_RS12135	COG2079	MmgE PrpD family protein
LCH16_RS12140	COG0372	Belongs to the citrate synthase family
LCH16_RS12145	COG1960	acyl-CoA dehydrogenase activity
LCH16_RS12150	COG1250	3-hydroxyacyl-CoA dehydrogenase
LCH16_RS12155	COG0183	Belongs to the thiolase family
LCH16_RS12160	COG0584	glycerophosphoryl diester phosphodiesterase
LCH16_RS12165	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCH16_RS12190	COG1902	pentaerythritol trinitrate reductase activity
LCH16_RS12205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LCH16_RS12210	COG0745	RESPONSE REGULATOR receiver
LCH16_RS12215	COG0750	zinc metalloprotease
LCH16_RS12220	COG0497	DNA recombination
LCH16_RS12230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LCH16_RS12240	COG0142	geranyltranstransferase activity
LCH16_RS12250	COG1570	exodeoxyribonuclease VII activity
LCH16_RS12265	COG1302	Protein conserved in bacteria
LCH16_RS12270	COG0439	Biotin carboxylase
LCH16_RS12275	COG0511	ligase activity, forming carbon-carbon bonds
LCH16_RS12315	COG3854	ATPases associated with a variety of cellular activities
LCH16_RS12330	COG0006	proline dipeptidase activity
LCH16_RS12340	COG3872	metal-dependent enzyme
LCH16_RS12350	COG1752	Esterase of the alpha-beta hydrolase superfamily
LCH16_RS12365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCH16_RS12385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LCH16_RS12400	COG1396	sequence-specific DNA binding
LCH16_RS12410	COG0681	Belongs to the peptidase S26 family
LCH16_RS12435	COG4940	Competence protein ComGF
LCH16_RS12445	COG4970	Tfp pilus assembly protein FimT
LCH16_RS12450	COG4537	Required for transformation and DNA binding
LCH16_RS12455	COG1459	type II secretion system
LCH16_RS12460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCH16_RS12465	COG0598	Magnesium transport protein CorA
LCH16_RS12470	COG1253	flavin adenine dinucleotide binding
LCH16_RS12475	COG1366	Belongs to the anti-sigma-factor antagonist family
LCH16_RS12485	COG1393	Belongs to the ArsC family
LCH16_RS12495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCH16_RS12505	COG0011	TIGRFAM Protein of
LCH16_RS12515	COG2866	Carboxypeptidase
LCH16_RS12520	COG1940	carbohydrate kinase activity
LCH16_RS12525	COG4483	Protein conserved in bacteria
LCH16_RS12530	COG1757	Na H antiporter
LCH16_RS12540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LCH16_RS12555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCH16_RS12560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCH16_RS12565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCH16_RS12570	COG0581	inorganic phosphate transmembrane transporter activity
LCH16_RS12575	COG0573	inorganic phosphate transmembrane transporter activity
LCH16_RS12580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LCH16_RS12585	COG0768	penicillin binding
LCH16_RS12590	COG0477	Major facilitator Superfamily
LCH16_RS12595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LCH16_RS12600	COG2839	Protein conserved in bacteria
LCH16_RS12605	COG5521	maltodextrose utilization protein MalA
LCH16_RS12610	COG1388	LysM domain
LCH16_RS12620	COG4709	membrane
LCH16_RS12625	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LCH16_RS12630	COG0735	belongs to the Fur family
LCH16_RS12635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCH16_RS12650	COG0513	Belongs to the DEAD box helicase family
LCH16_RS12665	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LCH16_RS12670	COG2384	SAM-dependent methyltransferase
LCH16_RS12675	COG2010	Cytochrome c
LCH16_RS12680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LCH16_RS12685	COG0358	DNA primase activity
LCH16_RS12700	COG0517	IMP dehydrogenase activity
LCH16_RS12705	COG0751	glycine-tRNA ligase activity
LCH16_RS12725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LCH16_RS12730	COG0295	cytidine deaminase activity
LCH16_RS12735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LCH16_RS12745	COG1480	7TM receptor with intracellular HD hydrolase
LCH16_RS12750	COG1702	phosphate starvation-inducible protein PhoH
LCH16_RS12755	COG0561	phosphatase activity
LCH16_RS12770	COG4864	UPF0365 protein
LCH16_RS12775	COG1030	water channel activity
LCH16_RS12780	COG1610	YqeY-like protein
LCH16_RS12790	COG1283	sodium-dependent phosphate transmembrane transporter activity
LCH16_RS12800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LCH16_RS12805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LCH16_RS12835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCH16_RS12850	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCH16_RS12880	COG0658	competence protein
LCH16_RS12880	COG2333	competence protein COMEC
LCH16_RS12885	COG2131	deaminase
LCH16_RS12890	COG1555	photosystem II stabilization
LCH16_RS12890	COG1596	polysaccharide export
LCH16_RS12895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCH16_RS12900	COG2226	methyltransferase
LCH16_RS12905	COG0799	negative regulation of ribosome biogenesis
LCH16_RS12910	COG1713	HD superfamily hydrolase involved in NAD metabolism
LCH16_RS12920	COG1534	Rna-binding protein
LCH16_RS12925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LCH16_RS12930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LCH16_RS12935	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LCH16_RS12945	COG2755	lipolytic protein G-D-S-L family
LCH16_RS12955	COG0398	Pfam SNARE associated Golgi protein
LCH16_RS12990	COG0642	Histidine kinase
LCH16_RS12990	COG5002	protein histidine kinase activity
LCH16_RS12995	COG0745	RESPONSE REGULATOR receiver
LCH16_RS13000	COG2311	Membrane
LCH16_RS13010	COG0454	-acetyltransferase
LCH16_RS13015	COG0563	adenylate kinase activity
LCH16_RS13025	COG2814	Major facilitator Superfamily
LCH16_RS13045	COG5444	nuclease activity
LCH16_RS13075	COG0456	acetyltransferase
LCH16_RS13080	COG2318	DinB family
LCH16_RS13090	COG0561	phosphatase activity
LCH16_RS13095	COG0561	phosphatase activity
LCH16_RS13105	COG1482	cell wall glycoprotein biosynthetic process
LCH16_RS13110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCH16_RS13110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCH16_RS13110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCH16_RS13115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCH16_RS13115	COG3711	transcriptional antiterminator
LCH16_RS13125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCH16_RS13130	COG0583	DNA-binding transcription factor activity
LCH16_RS13135	COG2814	Major facilitator Superfamily
LCH16_RS13140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LCH16_RS13140	COG2124	cytochrome p450
LCH16_RS13145	COG1309	transcriptional regulator
LCH16_RS13150	COG2226	methyltransferase
LCH16_RS13165	COG2116	formate transmembrane transporter activity
LCH16_RS13170	COG5609	conserved protein (DUF2294)
LCH16_RS13175	COG3383	formate dehydrogenase (NAD+) activity
LCH16_RS13180	COG2427	Protein of unknown function (DUF1641)
LCH16_RS13190	COG0626	cystathionine gamma-synthase activity
LCH16_RS13195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LCH16_RS13220	COG0768	penicillin binding
LCH16_RS13235	COG0826	peptidase U32
LCH16_RS13240	COG0826	peptidase U32
LCH16_RS13245	COG4122	O-methyltransferase activity
LCH16_RS13250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCH16_RS13265	COG4472	Bacterial protein of unknown function (DUF965)
LCH16_RS13275	COG0628	permease
LCH16_RS13280	COG1126	abc transporter atp-binding protein
LCH16_RS13285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCH16_RS13290	COG0765	amino acid transport
LCH16_RS13295	COG0765	amino acid transport
LCH16_RS13310	COG3881	PFAM PRC-barrel domain
LCH16_RS13315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LCH16_RS13320	COG0457	Tetratricopeptide repeat
LCH16_RS13330	COG1104	cysteine desulfurase activity
LCH16_RS13335	COG1959	2 iron, 2 sulfur cluster binding
LCH16_RS13340	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCH16_RS13345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LCH16_RS13370	COG4991	sh3 domain protein
LCH16_RS13370	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCH16_RS13370	COG3103	Sh3 type 3 domain protein
LCH16_RS13380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCH16_RS13390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LCH16_RS13390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LCH16_RS13395	COG5416	Lipopolysaccharide assembly protein A domain
LCH16_RS13400	COG0490	domain, Protein
LCH16_RS13405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LCH16_RS13405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LCH16_RS13415	COG2244	polysaccharide biosynthetic process
LCH16_RS13420	COG2323	membrane
LCH16_RS13430	COG1862	Preprotein translocase
LCH16_RS13470	COG1388	LysM domain
LCH16_RS13480	COG0157	Belongs to the NadC ModD family
LCH16_RS13485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LCH16_RS13490	COG1104	cysteine desulfurase activity
LCH16_RS13495	COG1827	regulation of RNA biosynthetic process
LCH16_RS13500	COG0077	Prephenate dehydratase
LCH16_RS13515	COG3290	protein histidine kinase activity
LCH16_RS13520	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LCH16_RS13525	COG2868	ribosomal protein
LCH16_RS13535	COG1994	Peptidase M50
LCH16_RS13540	COG0739	heme binding
LCH16_RS13545	COG2894	cell division
LCH16_RS13555	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LCH16_RS13565	COG1077	Cell shape determining protein MreB Mrl
LCH16_RS13585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LCH16_RS13590	COG0285	dihydrofolate synthase activity
LCH16_RS13595	COG0525	valine-tRNA ligase activity
LCH16_RS13605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LCH16_RS13610	COG1388	LysM domain
LCH16_RS13620	COG0113	porphobilinogen synthase activity
LCH16_RS13625	COG1587	Uroporphyrinogen-III synthase
LCH16_RS13635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LCH16_RS13655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LCH16_RS13660	COG0470	DNA polymerase III
LCH16_RS13660	COG1067	ATP-dependent peptidase activity
LCH16_RS13675	COG0457	Tetratricopeptide repeat
LCH16_RS13675	COG1477	protein flavinylation
LCH16_RS13690	COG0473	3-isopropylmalate dehydrogenase activity
LCH16_RS13705	COG0440	acetolactate synthase activity
LCH16_RS13710	COG0028	Belongs to the TPP enzyme family
LCH16_RS13740	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LCH16_RS13760	COG0622	Phosphoesterase
LCH16_RS13765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LCH16_RS13775	COG5401	PFAM Sporulation and spore germination
LCH16_RS13785	COG1846	Transcriptional regulator
LCH16_RS13790	COG2197	response regulator
LCH16_RS13795	COG0824	Thioesterase
LCH16_RS13800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LCH16_RS13805	COG1053	succinate dehydrogenase
LCH16_RS13810	COG2009	succinate dehydrogenase
LCH16_RS13815	COG1719	4-vinyl reductase, 4VR
LCH16_RS13820	COG0527	aspartate kinase activity
LCH16_RS13830	COG3118	belongs to the thioredoxin family
LCH16_RS13835	COG3534	alpha-L-arabinofuranosidase
LCH16_RS13840	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LCH16_RS13845	COG2086	electron transfer activity
LCH16_RS13850	COG1024	Enoyl-CoA hydratase
LCH16_RS13855	COG1309	transcriptional regulator
LCH16_RS13860	COG0318	PFAM AMP-dependent synthetase and ligase
LCH16_RS13870	COG3766	membrane
LCH16_RS13880	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LCH16_RS13880	COG1796	DNA polymerase
LCH16_RS13885	COG1286	toxin biosynthetic process
LCH16_RS13900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCH16_RS13900	COG0072	phenylalanine-tRNA ligase activity
LCH16_RS13905	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LCH16_RS13910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCH16_RS13920	COG3835	regulator
LCH16_RS13925	COG0277	FAD linked oxidase domain protein
LCH16_RS13930	COG0247	lactate metabolic process
LCH16_RS13935	COG1966	Carbon starvation protein
LCH16_RS13940	COG3534	alpha-L-arabinofuranosidase
LCH16_RS13945	COG0395	ABC-type sugar transport system, permease component
LCH16_RS13950	COG1175	transmembrane transport
LCH16_RS13955	COG1653	transport
LCH16_RS13965	COG0647	UMP catabolic process
LCH16_RS13970	COG0235	Class ii aldolase
LCH16_RS13975	COG1069	ribulokinase activity
LCH16_RS13980	COG2160	L-arabinose isomerase activity
LCH16_RS13985	COG3507	Belongs to the glycosyl hydrolase 43 family
LCH16_RS13990	COG1363	Peptidase, m42
LCH16_RS14000	COG3326	Membrane
LCH16_RS14005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LCH16_RS14015	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LCH16_RS14020	COG1346	cytolysis
LCH16_RS14025	COG1380	Effector of murein hydrolase LrgA
LCH16_RS14030	COG3279	Response regulator of the LytR AlgR family
LCH16_RS14035	COG3275	phosphorelay sensor kinase activity
LCH16_RS14040	COG1011	Hydrolase
LCH16_RS14055	COG0398	Pfam SNARE associated Golgi protein
LCH16_RS14060	COG1484	DNA-dependent DNA replication
LCH16_RS14065	COG3611	Membrane attachment protein
LCH16_RS14080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LCH16_RS14085	COG1733	regulation of RNA biosynthetic process
LCH16_RS14090	COG2814	Major facilitator Superfamily
LCH16_RS14095	COG0656	L-ascorbic acid biosynthetic process
LCH16_RS14100	COG0237	dephospho-CoA kinase activity
LCH16_RS14105	COG1971	Probably functions as a manganese efflux pump
LCH16_RS14110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LCH16_RS14115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCH16_RS14115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCH16_RS14120	COG5002	protein histidine kinase activity
LCH16_RS14125	COG0745	RESPONSE REGULATOR receiver
LCH16_RS14135	COG0538	isocitrate dehydrogenase activity
LCH16_RS14140	COG0372	Belongs to the citrate synthase family
LCH16_RS14160	COG0628	permease
LCH16_RS14165	COG3030	protein affecting phage T7 exclusion by the F plasmid
LCH16_RS14170	COG0469	pyruvate kinase activity
LCH16_RS14190	COG0281	malic enzyme
LCH16_RS14195	COG0587	DNA-directed DNA polymerase activity
LCH16_RS14215	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LCH16_RS14225	COG4109	DRTGG domain
LCH16_RS14235	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS14250	COG0521	Mo-molybdopterin cofactor biosynthetic process
LCH16_RS14260	COG0827	DNA restriction-modification system
LCH16_RS14265	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LCH16_RS14270	COG3874	Sporulation protein YtfJ
LCH16_RS14280	COG1714	RDD family
LCH16_RS14285	COG0616	signal peptide processing
LCH16_RS14290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LCH16_RS14295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LCH16_RS14300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LCH16_RS14315	COG1104	cysteine desulfurase activity
LCH16_RS14320	COG1114	Component of the transport system for branched-chain amino acids
LCH16_RS14330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LCH16_RS14335	COG1309	transcriptional regulator
LCH16_RS14340	COG1956	GAF domain-containing protein
LCH16_RS14345	COG2199	diguanylate cyclase activity
LCH16_RS14345	COG2203	Gaf domain
LCH16_RS14355	COG1012	belongs to the aldehyde dehydrogenase family
LCH16_RS14360	COG4282	regulation of fungal-type cell wall biogenesis
LCH16_RS14410	COG1017	nitric oxide dioxygenase activity
LCH16_RS14410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LCH16_RS14425	COG0693	protein deglycase activity
LCH16_RS14440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCH16_RS14445	COG1378	Sugar-specific transcriptional regulator TrmB
LCH16_RS14465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LCH16_RS14470	COG0454	-acetyltransferase
LCH16_RS14475	COG0517	IMP dehydrogenase activity
LCH16_RS14480	COG0123	including yeast histone deacetylase and acetoin utilization protein
LCH16_RS14485	COG1360	Flagellar Motor Protein
LCH16_RS14490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LCH16_RS14495	COG1609	Transcriptional regulator
LCH16_RS14500	COG1605	Chorismate mutase
LCH16_RS14500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LCH16_RS14505	COG3118	belongs to the thioredoxin family
LCH16_RS14510	COG4980	gas vesicle protein
LCH16_RS14515	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LCH16_RS14525	COG1674	ftsk spoiiie
LCH16_RS14530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCH16_RS14540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCH16_RS14550	COG1363	Peptidase, m42
LCH16_RS14555	COG5584	Small secreted protein
LCH16_RS14560	COG0281	malic enzyme
LCH16_RS14565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCH16_RS14580	COG0510	thiamine kinase activity
LCH16_RS14585	COG1597	lipid kinase activity
LCH16_RS14595	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LCH16_RS14600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LCH16_RS14605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCH16_RS14610	COG2252	PERMEase
LCH16_RS14615	COG4473	ABC transporter
LCH16_RS14620	COG1131	(ABC) transporter
LCH16_RS14625	COG1349	DNA-binding transcription factor activity
LCH16_RS14630	COG1187	pseudouridine synthase activity
LCH16_RS14635	COG2244	polysaccharide biosynthetic process
LCH16_RS14640	COG2081	HI0933 family
LCH16_RS14645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LCH16_RS14655	COG1609	Transcriptional regulator
LCH16_RS14660	COG1653	transport
LCH16_RS14665	COG1175	transmembrane transport
LCH16_RS14670	COG0395	ABC-type sugar transport system, permease component
LCH16_RS14675	COG1486	melibiose metabolic process
LCH16_RS14685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCH16_RS14700	COG1366	Belongs to the anti-sigma-factor antagonist family
LCH16_RS14700	COG2202	Pas domain
LCH16_RS14710	COG2814	Major facilitator Superfamily
LCH16_RS14715	COG5522	Integral membrane protein (intg_mem_TP0381)
LCH16_RS14720	COG0577	efflux transmembrane transporter activity
LCH16_RS14725	COG1136	(ABC) transporter
LCH16_RS14730	COG2205	protein histidine kinase activity
LCH16_RS14735	COG0745	RESPONSE REGULATOR receiver
LCH16_RS14740	COG0577	efflux transmembrane transporter activity
LCH16_RS14745	COG1136	(ABC) transporter
LCH16_RS14765	COG1131	(ABC) transporter
LCH16_RS14770	COG1725	Transcriptional regulator
LCH16_RS14785	COG0640	Transcriptional regulator
LCH16_RS14790	COG0477	Major facilitator Superfamily
LCH16_RS14795	COG1242	4 iron, 4 sulfur cluster binding
LCH16_RS14800	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LCH16_RS14810	COG0584	glycerophosphoryl diester phosphodiesterase
LCH16_RS14820	COG2267	carboxylic ester hydrolase activity
LCH16_RS14825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LCH16_RS14830	COG1113	amino acid transport
LCH16_RS14835	COG0367	asparagine synthase
LCH16_RS14860	COG1506	peptidase
LCH16_RS14865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LCH16_RS14870	COG1116	anion transmembrane transporter activity
LCH16_RS14875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCH16_RS14880	COG0494	nUDIX hydrolase
LCH16_RS14885	COG4824	toxin secretion phage lysis holin
LCH16_RS14890	COG0783	Belongs to the Dps family
LCH16_RS14915	COG0288	reversible hydration of carbon dioxide
LCH16_RS14925	COG1271	oxidase subunit
LCH16_RS14930	COG1294	oxidase, subunit
LCH16_RS14940	COG4948	Mandelate Racemase Muconate Lactonizing
LCH16_RS14950	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LCH16_RS14955	COG0596	Alpha beta hydrolase
LCH16_RS14965	COG1169	isochorismate synthase
LCH16_RS14970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LCH16_RS14975	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LCH16_RS15100	COG3859	Proton-coupled thiamine transporter YuaJ
LCH16_RS15105	COG2268	Band 7 protein
LCH16_RS15110	COG1585	Membrane protein implicated in regulation of membrane protease activity
LCH16_RS15115	COG2318	DinB family
LCH16_RS15125	COG1454	alcohol dehydrogenase
LCH16_RS15130	COG1012	belongs to the aldehyde dehydrogenase family
LCH16_RS15135	COG1510	regulation of RNA biosynthetic process
LCH16_RS15145	COG0569	domain protein
LCH16_RS15150	COG1705	Flagellar rod assembly protein muramidase FlgJ
LCH16_RS15155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LCH16_RS15155	COG1017	nitric oxide dioxygenase activity
LCH16_RS15180	COG0628	permease
LCH16_RS15185	COG0673	inositol 2-dehydrogenase activity
LCH16_RS15190	COG0693	protein deglycase activity
LCH16_RS15195	COG0840	transmembrane signaling receptor activity
LCH16_RS15200	COG0840	transmembrane signaling receptor activity
LCH16_RS15205	COG0840	transmembrane signaling receptor activity
LCH16_RS15210	COG0840	transmembrane signaling receptor activity
LCH16_RS15225	COG2070	2-Nitropropane dioxygenase
LCH16_RS15230	COG0432	Pfam Uncharacterised protein family UPF0047
LCH16_RS15235	COG0366	Alpha amylase catalytic
LCH16_RS15240	COG1253	flavin adenine dinucleotide binding
LCH16_RS15245	COG2738	Putative neutral zinc metallopeptidase
LCH16_RS15260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LCH16_RS15285	COG1335	isochorismatase
LCH16_RS15290	COG1979	alcohol dehydrogenase
LCH16_RS15295	COG1979	alcohol dehydrogenase
LCH16_RS15300	COG2155	Conserved Protein
LCH16_RS15305	COG1098	S1 RNA binding domain
LCH16_RS15310	COG0436	Aminotransferase
LCH16_RS15315	COG1522	sequence-specific DNA binding
LCH16_RS15320	COG2267	carboxylic ester hydrolase activity
LCH16_RS15330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LCH16_RS15335	COG2205	protein histidine kinase activity
LCH16_RS15345	COG5018	Exonuclease
LCH16_RS15350	COG2814	Major facilitator Superfamily
LCH16_RS15355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCH16_RS15360	COG3011	Protein conserved in bacteria
LCH16_RS15370	COG3290	protein histidine kinase activity
LCH16_RS15375	COG4565	transcriptional regulatory protein
LCH16_RS15380	COG1744	ABC transporter substrate-binding protein PnrA-like
LCH16_RS15385	COG3845	ABC transporter
LCH16_RS15390	COG4603	Belongs to the binding-protein-dependent transport system permease family
LCH16_RS15395	COG1079	Belongs to the binding-protein-dependent transport system permease family
LCH16_RS15405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LCH16_RS15405	COG2111	Na H antiporter
LCH16_RS15410	COG2111	Na H antiporter
LCH16_RS15415	COG1006	Multisubunit Na H antiporter MnhC subunit
LCH16_RS15420	COG0651	ATP synthesis coupled electron transport
LCH16_RS15425	COG1863	multisubunit Na H antiporter MnhE subunit
LCH16_RS15430	COG2212	antiporter activity
LCH16_RS15435	COG1320	monovalent cation:proton antiporter activity
LCH16_RS15440	COG2050	protein possibly involved in aromatic compounds catabolism
LCH16_RS15445	COG2197	response regulator
LCH16_RS15450	COG4585	Histidine kinase
LCH16_RS15460	COG0142	geranyltranstransferase activity
LCH16_RS15475	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LCH16_RS15480	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCH16_RS15485	COG1335	isochorismatase
LCH16_RS15490	COG5506	Protein of unknown function (DUF1694)
LCH16_RS15505	COG0628	permease
LCH16_RS15515	COG1418	mRNA catabolic process
LCH16_RS15520	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS15530	COG1511	domain protein
LCH16_RS15535	COG0433	COG0433 Predicted ATPase
LCH16_RS15535	COG1674	ftsk spoiiie
LCH16_RS15540	COG4499	WXG100 protein secretion system (Wss), protein YukC
LCH16_RS15545	COG5417	Belongs to the EsaB family
LCH16_RS15550	COG4842	Belongs to the WXG100 family
LCH16_RS15555	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LCH16_RS15555	COG2508	Transcriptional regulator
LCH16_RS15560	COG0686	Belongs to the AlaDH PNT family
LCH16_RS15565	COG5634	Uncharacterized conserved protein (DUF2278)
LCH16_RS15570	COG3251	PFAM MbtH domain protein
LCH16_RS15575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCH16_RS15580	COG3433	isochorismatase activity
LCH16_RS15580	COG1535	isochorismatase
LCH16_RS15585	COG1021	2,3-dihydroxybenzoate-AMP ligase
LCH16_RS15590	COG1169	isochorismate synthase
LCH16_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS15600	COG2819	hydrolase of the alpha beta superfamily
LCH16_RS15605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LCH16_RS15610	COG1268	BioY protein
LCH16_RS15615	COG2056	Na+-H+ antiporter family
LCH16_RS15625	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LCH16_RS15630	COG3584	3D domain protein
LCH16_RS15645	COG1252	NADH dehydrogenase
LCH16_RS15675	COG1131	(ABC) transporter
LCH16_RS15700	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LCH16_RS15715	COG0316	Belongs to the HesB IscA family
LCH16_RS15725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCH16_RS15735	COG1252	NADH dehydrogenase
LCH16_RS15740	COG4837	Protein of unknown function (DUF1462)
LCH16_RS15745	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LCH16_RS15750	COG0823	Involved in the tonB-independent uptake of proteins
LCH16_RS15750	COG1506	peptidase
LCH16_RS15750	COG4946	Tricorn protease homolog
LCH16_RS15760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LCH16_RS15765	COG0460	homoserine dehydrogenase
LCH16_RS15770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LCH16_RS15775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LCH16_RS15780	COG0647	UMP catabolic process
LCH16_RS15785	COG2445	Protein of unknown function DUF86
LCH16_RS15790	COG4470	Protein conserved in bacteria
LCH16_RS15800	COG0739	heme binding
LCH16_RS15810	COG0737	Belongs to the 5'-nucleotidase family
LCH16_RS15815	COG0730	response to heat
LCH16_RS15820	COG1801	Protein of unknown function DUF72
LCH16_RS15835	COG2508	Transcriptional regulator
LCH16_RS15840	COG0457	Tetratricopeptide repeat
LCH16_RS15855	COG2814	Major facilitator Superfamily
LCH16_RS15860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LCH16_RS15865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCH16_RS15870	COG2356	endonuclease I
LCH16_RS15875	COG3842	ATPase activity
LCH16_RS15880	COG2188	Transcriptional regulator
LCH16_RS15885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCH16_RS15890	COG0395	ABC-type sugar transport system, permease component
LCH16_RS15895	COG1175	transmembrane transport
LCH16_RS15900	COG1653	transport
LCH16_RS15905	COG2222	sugar isomerase
LCH16_RS15910	COG0789	Transcriptional regulator
LCH16_RS15925	COG0322	excinuclease ABC activity
LCH16_RS15930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCH16_RS15935	COG2226	methyltransferase
LCH16_RS15945	COG3409	Peptidoglycan-binding domain 1 protein
LCH16_RS15950	COG0719	Fe-S assembly protein
LCH16_RS15955	COG0822	iron-sulfur transferase activity
LCH16_RS15960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCH16_RS15965	COG0719	Fe-S assembly protein
LCH16_RS15970	COG0396	ATPase activity
LCH16_RS15980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LCH16_RS15985	COG1464	Belongs to the NlpA lipoprotein family
LCH16_RS15990	COG2011	ABC-type metal ion transport system permease component
LCH16_RS15995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LCH16_RS16005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCH16_RS16010	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LCH16_RS16025	COG1393	Belongs to the ArsC family
LCH16_RS16030	COG1960	acyl-CoA dehydrogenase activity
LCH16_RS16035	COG0183	Belongs to the thiolase family
LCH16_RS16040	COG1024	Enoyl-CoA hydratase
LCH16_RS16040	COG1250	3-hydroxyacyl-CoA dehydrogenase
LCH16_RS16055	COG0477	Major facilitator Superfamily
LCH16_RS16065	COG5577	PFAM Coat F domain
LCH16_RS16070	COG1846	Transcriptional regulator
LCH16_RS16075	COG0477	Major facilitator Superfamily
LCH16_RS16080	COG1942	4-Oxalocrotonate Tautomerase
LCH16_RS16085	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS16090	COG0583	DNA-binding transcription factor activity
LCH16_RS16100	COG0583	DNA-binding transcription factor activity
LCH16_RS16120	COG1120	ATPase activity
LCH16_RS16135	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS16140	COG0783	Belongs to the Dps family
LCH16_RS16145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCH16_RS16150	COG0745	RESPONSE REGULATOR receiver
LCH16_RS16155	COG2770	Histidine kinase
LCH16_RS16155	COG2205	protein histidine kinase activity
LCH16_RS16165	COG1309	transcriptional regulator
LCH16_RS16170	COG0114	fumarate hydratase activity
LCH16_RS16180	COG0697	spore germination
LCH16_RS16185	COG0814	amino acid
LCH16_RS16195	COG2197	response regulator
LCH16_RS16200	COG4585	Histidine kinase
LCH16_RS16205	COG4758	membrane
LCH16_RS16210	COG3595	metallopeptidase activity
LCH16_RS16215	COG1842	Phage shock protein A
LCH16_RS16220	COG4758	membrane
LCH16_RS16225	COG2814	Major facilitator Superfamily
LCH16_RS16230	COG2096	Adenosyltransferase
LCH16_RS16235	COG1120	ATPase activity
LCH16_RS16240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCH16_RS16245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCH16_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS16255	COG3386	PFAM SMP-30 Gluconolaconase
LCH16_RS16260	COG2205	protein histidine kinase activity
LCH16_RS16265	COG0745	RESPONSE REGULATOR receiver
LCH16_RS16275	COG1191	sigma factor activity
LCH16_RS16285	COG2140	Oxalate decarboxylase
LCH16_RS16295	COG1120	ATPase activity
LCH16_RS16300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCH16_RS16305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCH16_RS16310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCH16_RS16315	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LCH16_RS16320	COG0531	amino acid
LCH16_RS16330	COG1988	membrane-bound metal-dependent
LCH16_RS16335	COG1368	sulfuric ester hydrolase activity
LCH16_RS16340	COG1910	domain protein
LCH16_RS16345	COG0725	ABC transporter, periplasmic molybdate-binding protein
LCH16_RS16350	COG4149	molybdate abc transporter
LCH16_RS16355	COG2197	response regulator
LCH16_RS16360	COG3850	Histidine kinase
LCH16_RS16365	COG1131	(ABC) transporter
LCH16_RS16375	COG0842	Transport permease protein
LCH16_RS16380	COG0656	L-ascorbic acid biosynthetic process
LCH16_RS16400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LCH16_RS16405	COG3973	AAA domain
LCH16_RS16410	COG2860	membrane
LCH16_RS16420	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LCH16_RS16425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LCH16_RS16430	COG2217	Heavy metal translocating P-type atpase
LCH16_RS16435	COG2217	Heavy metal translocating P-type atpase
LCH16_RS16440	COG2608	mercury ion transmembrane transporter activity
LCH16_RS16445	COG1937	Protein conserved in bacteria
LCH16_RS16450	COG0673	inositol 2-dehydrogenase activity
LCH16_RS16465	COG2814	Major facilitator Superfamily
LCH16_RS16480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCH16_RS16485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LCH16_RS16490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCH16_RS16495	COG1126	abc transporter atp-binding protein
LCH16_RS16500	COG0765	amino acid transport
LCH16_RS16505	COG0765	amino acid transport
LCH16_RS16510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCH16_RS16515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCH16_RS16520	COG0454	-acetyltransferase
LCH16_RS16525	COG0583	DNA-binding transcription factor activity
LCH16_RS16530	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS16535	COG2732	(Barnase) inhibitor
LCH16_RS16540	COG2732	(Barnase) inhibitor
LCH16_RS16555	COG0557	exoribonuclease II activity
LCH16_RS16560	COG1647	Serine aminopeptidase, S33
LCH16_RS16565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LCH16_RS16570	COG1476	TRANSCRIPTIONal
LCH16_RS16575	COG1396	sequence-specific DNA binding
LCH16_RS16580	COG1396	sequence-specific DNA binding
LCH16_RS16585	COG1733	regulation of RNA biosynthetic process
LCH16_RS16610	COG1131	(ABC) transporter
LCH16_RS16615	COG1174	glycine betaine transport
LCH16_RS16620	COG1732	Glycine betaine
LCH16_RS16625	COG1174	glycine betaine transport
LCH16_RS16630	COG1125	glycine betaine transport
LCH16_RS16630	COG0517	IMP dehydrogenase activity
LCH16_RS16635	COG1510	regulation of RNA biosynthetic process
LCH16_RS16640	COG1174	glycine betaine transport
LCH16_RS16645	COG1732	Glycine betaine
LCH16_RS16650	COG1174	glycine betaine transport
LCH16_RS16655	COG1125	glycine betaine transport
LCH16_RS16655	COG0517	IMP dehydrogenase activity
LCH16_RS16660	COG1510	regulation of RNA biosynthetic process
LCH16_RS16665	COG2095	MarC family integral membrane protein
LCH16_RS16670	COG3064	Membrane
LCH16_RS16675	COG4640	response to antibiotic
LCH16_RS16680	COG0456	acetyltransferase
LCH16_RS16695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LCH16_RS16715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCH16_RS16720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LCH16_RS16730	COG2234	aminopeptidase activity
LCH16_RS16750	COG0126	phosphoglycerate kinase activity
LCH16_RS16755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LCH16_RS16760	COG2390	Transcriptional regulator
LCH16_RS16765	COG2814	Major facilitator Superfamily
LCH16_RS16770	COG1609	Transcriptional regulator
LCH16_RS16775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCH16_RS16785	COG0583	DNA-binding transcription factor activity
LCH16_RS16790	COG0697	spore germination
LCH16_RS16795	COG1113	amino acid transport
LCH16_RS16805	COG1609	Transcriptional regulator
LCH16_RS16815	COG0561	phosphatase activity
LCH16_RS16820	COG1737	Transcriptional regulator
LCH16_RS16825	COG1070	Carbohydrate kinase
LCH16_RS16855	COG2186	Transcriptional regulator
LCH16_RS16860	COG1620	l-lactate permease
LCH16_RS16865	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LCH16_RS16875	COG5039	Polysaccharide pyruvyl transferase
LCH16_RS16880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LCH16_RS16885	COG0110	maltose O-acetyltransferase activity
LCH16_RS16890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LCH16_RS16895	COG2244	polysaccharide biosynthetic process
LCH16_RS16900	COG1216	Glycosyl transferase, family 2
LCH16_RS16905	COG5039	Polysaccharide pyruvyl transferase
LCH16_RS16910	COG1216	Glycosyl transferase, family 2
LCH16_RS16920	COG0438	transferase activity, transferring glycosyl groups
LCH16_RS16925	COG1215	transferase activity, transferring glycosyl groups
LCH16_RS16930	COG0438	transferase activity, transferring glycosyl groups
LCH16_RS16935	COG1086	Polysaccharide biosynthesis protein
LCH16_RS16940	COG0489	protein tyrosine kinase activity
LCH16_RS16945	COG3944	biosynthesis protein
LCH16_RS16950	COG1396	sequence-specific DNA binding
LCH16_RS16955	COG2272	Belongs to the type-B carboxylesterase lipase family
LCH16_RS16960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LCH16_RS16965	COG2364	Membrane
LCH16_RS16970	COG0456	acetyltransferase
LCH16_RS16975	COG3479	Phenolic acid decarboxylase
LCH16_RS17045	COG2223	nitrite transmembrane transporter activity
LCH16_RS17050	COG1609	Transcriptional regulator
LCH16_RS17060	COG0583	DNA-binding transcription factor activity
LCH16_RS17065	COG2828	Protein conserved in bacteria
LCH16_RS17070	COG2814	Major facilitator Superfamily
LCH16_RS17070	COG0477	Major facilitator Superfamily
LCH16_RS17075	COG1611	Belongs to the LOG family
LCH16_RS17080	COG1694	Mazg nucleotide pyrophosphohydrolase
LCH16_RS17085	COG0659	secondary active sulfate transmembrane transporter activity
LCH16_RS17090	COG0288	reversible hydration of carbon dioxide
LCH16_RS17095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCH16_RS17100	COG4290	ribonuclease
LCH16_RS17105	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LCH16_RS17110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCH16_RS17120	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LCH16_RS17130	COG1051	belongs to the nudix hydrolase family
LCH16_RS17135	COG0492	ferredoxin-NADP+ reductase activity
LCH16_RS17140	COG3883	PFAM NLP P60 protein
LCH16_RS17140	COG0791	NLP P60 protein
LCH16_RS17145	COG0457	Tetratricopeptide repeat
LCH16_RS17150	COG5002	protein histidine kinase activity
LCH16_RS17155	COG0745	RESPONSE REGULATOR receiver
LCH16_RS17165	COG1132	(ABC) transporter
LCH16_RS17170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LCH16_RS17170	COG0140	phosphoribosyl-ATP diphosphatase activity
LCH16_RS17195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LCH16_RS17210	COG4990	cell redox homeostasis
LCH16_RS17215	COG0110	maltose O-acetyltransferase activity
LCH16_RS17235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCH16_RS17245	COG2188	Transcriptional regulator
LCH16_RS17250	COG1309	transcriptional regulator
LCH16_RS17255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LCH16_RS17260	COG1950	PFAM Membrane protein of
LCH16_RS17265	COG1983	PspC domain protein
LCH16_RS17270	COG3595	metallopeptidase activity
LCH16_RS17285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCH16_RS17295	COG4897	Protein conserved in bacteria
LCH16_RS17300	COG3848	Pyruvate phosphate dikinase
LCH16_RS17300	COG0574	Belongs to the PEP-utilizing enzyme family
LCH16_RS17305	COG1309	transcriptional regulator
LCH16_RS17310	COG2814	Major facilitator Superfamily
LCH16_RS17320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCH16_RS17330	COG3409	Peptidoglycan-binding domain 1 protein
LCH16_RS17330	COG0793	Belongs to the peptidase S41A family
LCH16_RS17335	COG3420	alginic acid biosynthetic process
LCH16_RS17340	COG2177	Part of the ABC transporter FtsEX involved in
LCH16_RS17345	COG2884	Cell division ATP-binding protein ftsE
LCH16_RS17350	COG2010	Cytochrome c
LCH16_RS17355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCH16_RS17370	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LCH16_RS17385	COG1516	flagellar protein fliS
LCH16_RS17390	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LCH16_RS17395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LCH16_RS17415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LCH16_RS17420	COG1256	bacterial-type flagellum assembly
LCH16_RS17420	COG4786	Flagellar basal body rod
LCH16_RS17425	COG3418	PFAM FlgN family protein
LCH16_RS17430	COG2747	anti-sigma28 factor FlgM
LCH16_RS17440	COG1040	competence protein
LCH16_RS17450	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LCH16_RS17455	COG1307	EDD domain protein, DegV family
LCH16_RS17460	COG2197	response regulator
LCH16_RS17465	COG4585	Histidine kinase
LCH16_RS17470	COG1739	Uncharacterized protein family UPF0029
LCH16_RS17475	COG1316	TRANSCRIPTIONal
LCH16_RS17480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCH16_RS17485	COG0438	transferase activity, transferring glycosyl groups
LCH16_RS17490	COG1215	transferase activity, transferring glycosyl groups
LCH16_RS17495	COG3206	protein involved in exopolysaccharide biosynthesis
LCH16_RS17500	COG3307	-O-antigen
LCH16_RS17505	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LCH16_RS17510	COG0297	glycogen (starch) synthase activity
LCH16_RS17510	COG0438	transferase activity, transferring glycosyl groups
LCH16_RS17515	COG2244	polysaccharide biosynthetic process
LCH16_RS17525	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCH16_RS17525	COG2247	cell wall binding repeat
LCH16_RS17530	COG2247	cell wall binding repeat
LCH16_RS17530	COG2385	sporulation resulting in formation of a cellular spore
LCH16_RS17540	COG1316	TRANSCRIPTIONal
LCH16_RS17545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LCH16_RS17550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LCH16_RS17555	COG1134	teichoic acid transport
LCH16_RS17560	COG1682	transport, permease protein
LCH16_RS17565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LCH16_RS17570	COG0438	transferase activity, transferring glycosyl groups
LCH16_RS17575	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LCH16_RS17580	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LCH16_RS17585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LCH16_RS17590	COG4193	domain, Protein
LCH16_RS17595	COG1482	cell wall glycoprotein biosynthetic process
LCH16_RS17600	COG0697	spore germination
LCH16_RS17605	COG0814	amino acid
LCH16_RS17615	COG1215	transferase activity, transferring glycosyl groups
LCH16_RS17620	COG2814	Major facilitator Superfamily
LCH16_RS17625	COG1316	TRANSCRIPTIONal
LCH16_RS17630	COG0561	phosphatase activity
LCH16_RS17635	COG2433	Pfam Transposase IS66
LCH16_RS17640	COG0791	NLP P60 protein
LCH16_RS17650	COG2843	Capsule synthesis protein
LCH16_RS17660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LCH16_RS17665	COG0697	spore germination
LCH16_RS17670	COG0814	amino acid
LCH16_RS17680	COG1609	Transcriptional regulator
LCH16_RS17685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCH16_RS17695	COG1129	ABC transporter
LCH16_RS17700	COG1172	Belongs to the binding-protein-dependent transport system permease family
LCH16_RS17705	COG1879	ABC-type sugar transport system periplasmic component
LCH16_RS17710	COG3103	Sh3 type 3 domain protein
LCH16_RS17715	COG2249	NAD(P)H dehydrogenase (quinone) activity
LCH16_RS17720	COG3527	Alpha-acetolactate decarboxylase
LCH16_RS17725	COG0028	Belongs to the TPP enzyme family
LCH16_RS17730	COG0583	DNA-binding transcription factor activity
LCH16_RS17735	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LCH16_RS17750	COG5337	Spore coat protein CotH
LCH16_RS17760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LCH16_RS17765	COG0405	Gamma-glutamyltransferase
LCH16_RS17770	COG1522	sequence-specific DNA binding
LCH16_RS17775	COG2059	Chromate
LCH16_RS17780	COG2059	Chromate
LCH16_RS17820	COG3878	Protein conserved in bacteria
LCH16_RS17825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LCH16_RS17830	COG4464	protein tyrosine phosphatase activity
LCH16_RS17835	COG0489	protein tyrosine kinase activity
LCH16_RS17840	COG3944	biosynthesis protein
LCH16_RS17850	COG4715	Zinc finger, swim domain protein
LCH16_RS17855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LCH16_RS17860	COG0561	phosphatase activity
LCH16_RS17865	COG1349	DNA-binding transcription factor activity
LCH16_RS17870	COG0629	single-stranded DNA binding
LCH16_RS17895	COG0457	Tetratricopeptide repeat
LCH16_RS17900	COG4786	Flagellar basal body rod
LCH16_RS17905	COG4786	Flagellar basal body rod
LCH16_RS17910	COG1077	Cell shape determining protein MreB Mrl
LCH16_RS17915	COG1609	Transcriptional regulator
LCH16_RS17920	COG1846	Transcriptional regulator
LCH16_RS17925	COG2814	Major facilitator Superfamily
LCH16_RS17930	COG1953	Uracil, thiamine, allantoin
LCH16_RS17935	COG0477	Major facilitator Superfamily
LCH16_RS17940	COG1335	isochorismatase
LCH16_RS17945	COG0004	ammonium transporteR
LCH16_RS17950	COG0347	Belongs to the P(II) protein family
LCH16_RS17955	COG0772	Belongs to the SEDS family
LCH16_RS17960	COG0671	phosphoesterase, PA-phosphatase related
LCH16_RS17970	COG0739	heme binding
LCH16_RS17975	COG1247	-acetyltransferase
LCH16_RS17990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCH16_RS18000	COG0726	polysaccharide deacetylase
LCH16_RS18005	COG1959	2 iron, 2 sulfur cluster binding
LCH16_RS18020	COG0831	urea catabolic process
LCH16_RS18030	COG1994	Peptidase M50
LCH16_RS18035	COG0457	Tetratricopeptide repeat
LCH16_RS18045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LCH16_RS18055	COG2304	oxidoreductase activity
LCH16_RS18060	COG2304	oxidoreductase activity
LCH16_RS18065	COG2385	sporulation resulting in formation of a cellular spore
LCH16_RS18070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCH16_RS18080	COG4836	Membrane
LCH16_RS18150	COG0698	ribose 5-phosphate isomerase
LCH16_RS18155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LCH16_RS18165	COG0009	L-threonylcarbamoyladenylate synthase
LCH16_RS18170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LCH16_RS18190	COG2890	protein-(glutamine-N5) methyltransferase activity
LCH16_RS18195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LCH16_RS18200	COG0346	lactoylglutathione lyase activity
LCH16_RS18205	COG0789	Transcriptional regulator
LCH16_RS18210	COG0679	Auxin Efflux Carrier
LCH16_RS18215	COG0281	malic enzyme
LCH16_RS18230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LCH16_RS18240	COG1494	fructose-1,6-bisphosphatase
LCH16_RS18245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCH16_RS18255	COG0191	fructose-bisphosphate aldolase activity
LCH16_RS18260	COG2204	response regulator
LCH16_RS18265	COG4821	SIS domain
LCH16_RS18280	COG0247	lactate metabolic process
LCH16_RS18280	COG2181	nitrate reductase activity
LCH16_RS18285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCH16_RS18300	COG1132	(ABC) transporter
LCH16_RS18305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCH16_RS18315	COG2181	nitrate reductase activity
LCH16_RS18320	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LCH16_RS18325	COG1140	nitrate reductase beta subunit
LCH16_RS18330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LCH16_RS18335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCH16_RS18345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCH16_RS18350	COG2223	nitrite transmembrane transporter activity
LCH16_RS18360	COG4506	Protein conserved in bacteria
LCH16_RS18375	COG3391	amine dehydrogenase activity
LCH16_RS18380	COG0457	Tetratricopeptide repeat
LCH16_RS18420	COG0010	Belongs to the arginase family
LCH16_RS18425	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LCH16_RS18430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCH16_RS18445	COG1994	Peptidase M50
LCH16_RS18450	COG1942	4-Oxalocrotonate Tautomerase
LCH16_RS18455	COG1846	Transcriptional regulator
LCH16_RS18460	COG0531	amino acid
LCH16_RS18465	COG3465	dGTPase activity
LCH16_RS18470	COG1078	dGTPase activity
LCH16_RS18485	COG1695	Transcriptional regulator
LCH16_RS18495	COG1131	(ABC) transporter
LCH16_RS18500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LCH16_RS18530	COG0583	DNA-binding transcription factor activity
LCH16_RS18535	COG2855	membrane
LCH16_RS18540	COG0280	phosphate acetyltransferase
LCH16_RS18550	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS18555	COG0436	Aminotransferase
LCH16_RS18585	COG2814	Major facilitator Superfamily
LCH16_RS18590	COG2814	Major facilitator Superfamily
LCH16_RS18595	COG0833	amino acid
LCH16_RS18600	COG4187	Peptidase family M20/M25/M40
LCH16_RS18605	COG1012	belongs to the aldehyde dehydrogenase family
LCH16_RS18610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LCH16_RS18620	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LCH16_RS18625	COG1091	dTDP-4-dehydrorhamnose reductase activity
LCH16_RS18630	COG1088	dTDP-glucose 4,6-dehydratase activity
LCH16_RS18635	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LCH16_RS18640	COG3980	spore coat polysaccharide biosynthesis protein
LCH16_RS18645	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LCH16_RS18650	COG2089	acid synthase
LCH16_RS18655	COG0456	acetyltransferase
LCH16_RS18660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LCH16_RS18665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LCH16_RS18670	COG0463	Glycosyl transferase, family 2
LCH16_RS18680	COG2363	Small membrane protein
LCH16_RS18685	COG2233	PERMEase
LCH16_RS18700	COG1216	Glycosyl transferase, family 2
LCH16_RS18715	COG1695	Transcriptional regulator
LCH16_RS18720	COG0351	phosphomethylpyrimidine kinase
LCH16_RS18730	COG1621	beta-fructofuranosidase activity
LCH16_RS18735	COG1263	PTS System
LCH16_RS18735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCH16_RS18740	COG3711	transcriptional antiterminator
LCH16_RS18750	COG1404	Belongs to the peptidase S8 family
LCH16_RS18755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCH16_RS18760	COG0778	Nitroreductase
LCH16_RS18765	COG0772	Belongs to the SEDS family
LCH16_RS18770	COG0454	-acetyltransferase
LCH16_RS18790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LCH16_RS18795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LCH16_RS18800	COG2261	transglycosylase associated protein
LCH16_RS18805	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LCH16_RS18810	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LCH16_RS18815	COG2246	polysaccharide biosynthetic process
LCH16_RS18820	COG1309	transcriptional regulator
LCH16_RS18840	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LCH16_RS18845	COG2837	iron assimilation
LCH16_RS18865	COG0583	DNA-binding transcription factor activity
LCH16_RS18875	COG1346	cytolysis
LCH16_RS18880	COG4895	conserved protein (DUF2196)
LCH16_RS18890	COG0789	Transcriptional regulator
LCH16_RS18895	COG5504	Zn-dependent protease
LCH16_RS18900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LCH16_RS18905	COG0346	lactoylglutathione lyase activity
LCH16_RS18910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCH16_RS18915	COG1404	Belongs to the peptidase S8 family
LCH16_RS18920	COG1442	glycosyl transferase family 8
LCH16_RS18925	COG2357	RelA SpoT domain protein
LCH16_RS18930	COG1575	Belongs to the MenA family. Type 1 subfamily
LCH16_RS18945	COG1696	Membrane protein involved in D-alanine export
LCH16_RS18955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LCH16_RS18960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCH16_RS18965	COG1486	melibiose metabolic process
LCH16_RS18970	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCH16_RS18975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCH16_RS18980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCH16_RS18985	COG3711	transcriptional antiterminator
LCH16_RS18985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCH16_RS18995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCH16_RS19000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCH16_RS19010	COG0640	Transcriptional regulator
LCH16_RS19015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LCH16_RS19020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCH16_RS19025	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCH16_RS19030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCH16_RS19035	COG2723	6-phospho-beta-galactosidase activity
LCH16_RS19040	COG1940	carbohydrate kinase activity
LCH16_RS19045	COG1482	cell wall glycoprotein biosynthetic process
LCH16_RS19055	COG0753	catalase activity
LCH16_RS19060	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LCH16_RS19065	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LCH16_RS19070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LCH16_RS19075	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LCH16_RS19080	COG4988	ABC transporter
LCH16_RS19085	COG1294	oxidase, subunit
LCH16_RS19090	COG1271	oxidase subunit
LCH16_RS19095	COG3493	citrate carrier protein
LCH16_RS19100	COG0726	polysaccharide deacetylase
LCH16_RS19105	COG3842	ATPase activity
LCH16_RS19110	COG2508	Transcriptional regulator
LCH16_RS19115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCH16_RS19125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCH16_RS19140	COG4894	glucomannan catabolic process
LCH16_RS19145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LCH16_RS19155	COG0500	methyltransferase
LCH16_RS19160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCH16_RS19180	COG0753	catalase activity
LCH16_RS19180	COG0693	protein deglycase activity
LCH16_RS19185	COG2851	Citrate transporter
LCH16_RS19190	COG2273	Hydrolase Family 16
LCH16_RS19195	COG3711	transcriptional antiterminator
LCH16_RS19200	COG2270	Major facilitator Superfamily
LCH16_RS19205	COG0513	Belongs to the DEAD box helicase family
LCH16_RS19290	COG0697	spore germination
LCH16_RS19295	COG0589	response to stress
LCH16_RS19360	COG3507	Belongs to the glycosyl hydrolase 43 family
LCH16_RS19385	COG0010	Belongs to the arginase family
LCH16_RS19390	COG0833	amino acid
LCH16_RS19395	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LCH16_RS19400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCH16_RS19410	COG2390	Transcriptional regulator
LCH16_RS19415	COG0561	phosphatase activity
LCH16_RS19445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCH16_RS19450	COG5294	Protein conserved in bacteria
LCH16_RS19455	COG0577	efflux transmembrane transporter activity
LCH16_RS19460	COG1136	(ABC) transporter
LCH16_RS19465	COG2205	protein histidine kinase activity
LCH16_RS19470	COG0745	RESPONSE REGULATOR receiver
LCH16_RS19475	COG2205	protein histidine kinase activity
LCH16_RS19480	COG0745	RESPONSE REGULATOR receiver
LCH16_RS19510	COG1082	Xylose isomerase domain protein TIM barrel
LCH16_RS19520	COG2814	Major facilitator Superfamily
LCH16_RS19550	COG1349	DNA-binding transcription factor activity
LCH16_RS19555	COG0667	Aldo Keto reductase
LCH16_RS19560	COG2814	Major facilitator Superfamily
LCH16_RS19575	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS19580	COG2197	response regulator
LCH16_RS19585	COG4585	Histidine kinase
LCH16_RS19590	COG3239	Fatty acid desaturase
LCH16_RS19595	COG1309	transcriptional regulator
LCH16_RS19600	COG1012	belongs to the aldehyde dehydrogenase family
LCH16_RS19605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LCH16_RS19615	COG0640	Transcriptional regulator
LCH16_RS19625	COG1714	RDD family
LCH16_RS19635	COG0450	alkyl hydroperoxide reductase
LCH16_RS19640	COG3634	alkyl hydroperoxide reductase activity
LCH16_RS19650	COG1113	amino acid transport
LCH16_RS19660	COG2080	2 iron, 2 sulfur cluster binding
LCH16_RS19675	COG2068	MobA-Related Protein
LCH16_RS19680	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LCH16_RS19740	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LCH16_RS19745	COG0667	Aldo Keto reductase
LCH16_RS19750	COG0456	acetyltransferase
LCH16_RS19755	COG0457	Tetratricopeptide repeat
LCH16_RS19760	COG0010	Belongs to the arginase family
LCH16_RS19765	COG0833	amino acid
LCH16_RS19770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LCH16_RS19775	COG5658	integral membrane protein
LCH16_RS19780	COG0640	Transcriptional regulator
LCH16_RS19785	COG3829	transcription factor binding
LCH16_RS19795	COG0488	(ABC) transporter
LCH16_RS19810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LCH16_RS19815	COG5002	protein histidine kinase activity
LCH16_RS19815	COG3850	Histidine kinase
LCH16_RS19820	COG0745	RESPONSE REGULATOR receiver
LCH16_RS19825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCH16_RS19830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LCH16_RS19835	COG4853	Protein conserved in bacteria
LCH16_RS19840	COG4863	YycH protein
LCH16_RS19845	COG5002	protein histidine kinase activity
LCH16_RS19850	COG0745	RESPONSE REGULATOR receiver
LCH16_RS19880	COG0346	lactoylglutathione lyase activity
LCH16_RS19885	COG0305	Participates in initiation and elongation during chromosome replication
LCH16_RS19900	COG3093	addiction module antidote protein HigA
LCH16_RS19905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LCH16_RS19910	COG0297	glycogen (starch) synthase activity
LCH16_RS19920	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LCH16_RS19925	COG0438	transferase activity, transferring glycosyl groups
LCH16_RS19945	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LCH16_RS19950	COG4241	membrane
LCH16_RS19960	COG5577	PFAM Coat F domain
LCH16_RS19965	COG1733	regulation of RNA biosynthetic process
LCH16_RS19975	COG0697	spore germination
LCH16_RS19980	COG1621	beta-fructofuranosidase activity
LCH16_RS19985	COG1621	beta-fructofuranosidase activity
LCH16_RS19990	COG1802	Transcriptional regulator
LCH16_RS19995	COG2318	DinB family
LCH16_RS20000	COG2211	Major facilitator Superfamily
LCH16_RS20005	COG0583	DNA-binding transcription factor activity
LCH16_RS20020	COG0778	Nitroreductase
LCH16_RS20025	COG1846	Transcriptional regulator
LCH16_RS20030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCH16_RS20035	COG1846	Transcriptional regulator
LCH16_RS20040	COG2153	protein acetylation
LCH16_RS20050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LCH16_RS20055	COG0583	DNA-binding transcription factor activity
LCH16_RS20060	COG1028	Short-chain dehydrogenase reductase Sdr
LCH16_RS20065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCH16_RS20070	COG0697	spore germination
LCH16_RS20075	COG1331	Highly conserved protein containing a thioredoxin domain
LCH16_RS20080	COG1266	CAAX protease self-immunity
LCH16_RS20085	COG2814	Major facilitator Superfamily
LCH16_RS20085	COG0477	Major facilitator Superfamily
LCH16_RS20090	COG0346	lactoylglutathione lyase activity
LCH16_RS20095	COG1609	Transcriptional regulator
LCH16_RS20100	COG0708	Exodeoxyribonuclease III
LCH16_RS20105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LCH16_RS20110	COG2169	Transcriptional regulator
LCH16_RS20120	COG0629	single-stranded DNA binding
LCH16_RS20130	COG0012	GTP binding
LCH16_RS20135	COG0243	molybdopterin cofactor binding
LCH16_RS20140	COG4481	Protein conserved in bacteria
LCH16_RS20145	COG3949	Membrane
LCH16_RS20160	COG1475	DNA binding
LCH16_RS20165	COG1192	Involved in chromosome partitioning
LCH16_RS20190	COG1847	R3H domain protein
LCH16_RS20195	COG0706	membrane insertase activity
LCH16_RS20275	COG5444	nuclease activity