locus-tag	class	description
NYR48_RS00010	COG0592	DNA-directed DNA polymerase activity
NYR48_RS00015	COG2501	S4 domain
NYR48_RS00030	COG0187	DNA topoisomerase II activity
NYR48_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NYR48_RS00070	COG0516	GMP reductase activity
NYR48_RS00070	COG0517	IMP dehydrogenase activity
NYR48_RS00075	COG1686	Belongs to the peptidase S11 family
NYR48_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
NYR48_RS00105	COG1428	Deoxynucleoside kinase
NYR48_RS00110	COG1428	Deoxynucleoside kinase
NYR48_RS00115	COG1388	LysM domain
NYR48_RS00115	COG3858	chitin binding
NYR48_RS00120	COG1335	isochorismatase
NYR48_RS00125	COG0590	tRNA wobble adenosine to inosine editing
NYR48_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NYR48_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NYR48_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NYR48_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NYR48_RS00195	COG3853	Toxic anion resistance protein (TelA)
NYR48_RS00200	COG1982	Orn Lys Arg decarboxylase major
NYR48_RS00210	COG3870	Protein conserved in bacteria
NYR48_RS00215	COG1728	Protein conserved in bacteria
NYR48_RS00220	COG0470	DNA polymerase III
NYR48_RS00225	COG1774	PSP1 C-terminal conserved region
NYR48_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NYR48_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NYR48_RS00250	COG2002	toxin-antitoxin pair type II binding
NYR48_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NYR48_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NYR48_RS00260	COG0084	hydrolase, TatD family'
NYR48_RS00265	COG3584	3D domain protein
NYR48_RS00265	COG3583	domain protein
NYR48_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NYR48_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NYR48_RS00285	COG4466	Protein conserved in bacteria
NYR48_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NYR48_RS00305	COG0251	oxidation-reduction process
NYR48_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NYR48_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NYR48_RS00345	COG2002	toxin-antitoxin pair type II binding
NYR48_RS00350	COG2244	polysaccharide biosynthetic process
NYR48_RS00355	COG3956	TIGRFAM MazG family protein
NYR48_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NYR48_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NYR48_RS00380	COG1098	S1 RNA binding domain
NYR48_RS00395	COG2208	phosphoserine phosphatase activity
NYR48_RS00400	COG2304	oxidoreductase activity
NYR48_RS00405	COG0515	serine threonine protein kinase
NYR48_RS00410	COG0037	tRNA processing
NYR48_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NYR48_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NYR48_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NYR48_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NYR48_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NYR48_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
NYR48_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NYR48_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NYR48_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NYR48_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NYR48_RS00475	COG1396	sequence-specific DNA binding
NYR48_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NYR48_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NYR48_RS00565	COG4463	regulation of RNA biosynthetic process
NYR48_RS00570	COG3880	PFAM UvrB UvrC protein
NYR48_RS00580	COG0542	response to heat
NYR48_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NYR48_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NYR48_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
NYR48_RS00615	COG1045	serine acetyltransferase
NYR48_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NYR48_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NYR48_RS00635	COG3688	RNA-binding protein containing a PIN domain
NYR48_RS00640	COG1595	DNA-templated transcription, initiation
NYR48_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NYR48_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
NYR48_RS00680	COG2813	Specifically methylates the guanine in position
NYR48_RS00695	COG1358	cellular component organization or biogenesis
NYR48_RS00720	COG0596	Alpha beta hydrolase
NYR48_RS00830	COG0201	protein transport
NYR48_RS00840	COG0024	Methionine aminopeptidase
NYR48_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NYR48_RS00880	COG1122	ATPase activity
NYR48_RS00885	COG1122	ATPase activity
NYR48_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NYR48_RS00910	COG2226	methyltransferase
NYR48_RS00915	COG2318	DinB family
NYR48_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
NYR48_RS00930	COG0489	protein tyrosine kinase activity
NYR48_RS00940	COG2194	sulfuric ester hydrolase activity
NYR48_RS00945	COG0726	polysaccharide deacetylase
NYR48_RS01005	COG0738	Major facilitator superfamily
NYR48_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NYR48_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
NYR48_RS01030	COG0385	Bile acid
NYR48_RS01035	COG2819	hydrolase of the alpha beta superfamily
NYR48_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYR48_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYR48_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NYR48_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NYR48_RS01055	COG2207	Transcriptional regulator
NYR48_RS01060	COG3876	Protein conserved in bacteria
NYR48_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
NYR48_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NYR48_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NYR48_RS01075	COG1263	PTS System
NYR48_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NYR48_RS01090	COG1683	Conserved Protein
NYR48_RS01120	COG1595	DNA-templated transcription, initiation
NYR48_RS01125	COG5662	AntiSigma factor
NYR48_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NYR48_RS01135	COG4856	YbbR-like protein
NYR48_RS01175	COG1346	cytolysis
NYR48_RS01180	COG1380	Effector of murein hydrolase LrgA
NYR48_RS01185	COG1846	Transcriptional regulator
NYR48_RS01190	COG1113	amino acid transport
NYR48_RS01195	COG1011	Hydrolase
NYR48_RS01200	COG4585	Histidine kinase
NYR48_RS01205	COG2197	response regulator
NYR48_RS01210	COG1131	(ABC) transporter
NYR48_RS01250	COG0531	amino acid
NYR48_RS01255	COG0584	glycerophosphoryl diester phosphodiesterase
NYR48_RS01260	COG2271	Major facilitator Superfamily
NYR48_RS01270	COG2368	4-hydroxyphenylacetate
NYR48_RS01280	COG3409	Peptidoglycan-binding domain 1 protein
NYR48_RS01295	COG0371	Dehydrogenase
NYR48_RS01305	COG1183	phosphatidylcholine synthase activity
NYR48_RS01310	COG0586	Pfam SNARE associated Golgi protein
NYR48_RS01315	COG0688	phosphatidylethanolamine metabolic process
NYR48_RS01330	COG1301	dicarboxylic acid transport
NYR48_RS01335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NYR48_RS01340	COG0833	amino acid
NYR48_RS01345	COG2040	homocysteine
NYR48_RS01350	COG1115	amino acid carrier protein
NYR48_RS01355	COG2066	Belongs to the glutaminase family
NYR48_RS01360	COG4191	Histidine kinase
NYR48_RS01365	COG0784	Response regulator, receiver
NYR48_RS01385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NYR48_RS01390	COG0778	Nitroreductase
NYR48_RS01395	COG0346	lactoylglutathione lyase activity
NYR48_RS01400	COG2259	Doxx family
NYR48_RS01405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYR48_RS01415	COG3773	Cell wall hydrolase
NYR48_RS01420	COG3540	Alkaline phosphatase
NYR48_RS01425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NYR48_RS01430	COG0805	protein transport
NYR48_RS01440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NYR48_RS01445	COG0477	Major facilitator Superfamily
NYR48_RS01450	COG1309	transcriptional regulator
NYR48_RS01455	COG0252	asparaginase activity
NYR48_RS01460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NYR48_RS01465	COG1405	negative regulation of cell septum assembly
NYR48_RS01465	COG3012	SEC-C Motif Domain Protein
NYR48_RS01470	COG0667	Aldo Keto reductase
NYR48_RS01480	COG1595	DNA-templated transcription, initiation
NYR48_RS01485	COG1595	DNA-templated transcription, initiation
NYR48_RS01495	COG0457	Tetratricopeptide repeat
NYR48_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS01505	COG0366	Alpha amylase catalytic
NYR48_RS01515	COG1695	Transcriptional regulator
NYR48_RS01520	COG0803	Belongs to the bacterial solute-binding protein 9 family
NYR48_RS01525	COG1121	(ABC) transporter
NYR48_RS01530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NYR48_RS01535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYR48_RS01540	COG2310	stress, protein
NYR48_RS01545	COG2310	stress, protein
NYR48_RS01550	COG2310	stress, protein
NYR48_RS01555	COG0861	Integral membrane protein TerC family
NYR48_RS01565	COG3853	Toxic anion resistance protein (TelA)
NYR48_RS01570	COG0477	Major facilitator Superfamily
NYR48_RS01575	COG0517	IMP dehydrogenase activity
NYR48_RS01575	COG4175	Glycine betaine
NYR48_RS01580	COG4176	ABC-type proline glycine betaine transport system permease component
NYR48_RS01585	COG2113	Glycine betaine
NYR48_RS01590	COG1473	amidohydrolase
NYR48_RS01595	COG1288	antiporter activity
NYR48_RS01605	COG0366	Alpha amylase catalytic
NYR48_RS01615	COG2814	Major facilitator Superfamily
NYR48_RS01620	COG1846	Transcriptional regulator
NYR48_RS01625	COG1280	lysine exporter protein (LysE YggA)
NYR48_RS01630	COG3403	YqcI/YcgG family
NYR48_RS01635	COG1113	amino acid transport
NYR48_RS01640	COG3665	Urea carboxylase-associated protein
NYR48_RS01655	COG1660	Displays ATPase and GTPase activities
NYR48_RS01660	COG1082	Xylose isomerase domain protein TIM barrel
NYR48_RS01665	COG2271	Major facilitator Superfamily
NYR48_RS01670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NYR48_RS01680	COG3458	cephalosporin-C deacetylase activity
NYR48_RS01685	COG3541	Predicted nucleotidyltransferase
NYR48_RS01690	COG0506	proline dehydrogenase activity
NYR48_RS01695	COG1012	belongs to the aldehyde dehydrogenase family
NYR48_RS01700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NYR48_RS01705	COG2508	Transcriptional regulator
NYR48_RS01715	COG1587	Uroporphyrinogen-III synthase
NYR48_RS01715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NYR48_RS01720	COG2146	nitrite reductase [NAD(P)H] activity
NYR48_RS01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NYR48_RS01730	COG0243	molybdopterin cofactor binding
NYR48_RS01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NYR48_RS01740	COG2223	nitrite transmembrane transporter activity
NYR48_RS01745	COG0523	cobalamin synthesis protein
NYR48_RS01750	COG1063	alcohol dehydrogenase
NYR48_RS01755	COG1714	RDD family
NYR48_RS01765	COG2723	6-phospho-beta-galactosidase activity
NYR48_RS01775	COG3209	COG3209 Rhs family protein
NYR48_RS01780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NYR48_RS01785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NYR48_RS01790	COG1733	regulation of RNA biosynthetic process
NYR48_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS01815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS01820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS01825	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NYR48_RS01840	COG2364	Membrane
NYR48_RS01845	COG1126	abc transporter atp-binding protein
NYR48_RS01850	COG0765	amino acid transport
NYR48_RS01855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NYR48_RS01860	COG0583	DNA-binding transcription factor activity
NYR48_RS01865	COG0163	prenyltransferase activity
NYR48_RS01870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NYR48_RS01885	COG3104	oligopeptide transport
NYR48_RS01890	COG5434	Belongs to the glycosyl hydrolase 28 family
NYR48_RS01900	COG0697	spore germination
NYR48_RS01910	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NYR48_RS01915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYR48_RS01920	COG0456	acetyltransferase
NYR48_RS01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NYR48_RS01930	COG0765	amino acid transport
NYR48_RS01935	COG1126	abc transporter atp-binding protein
NYR48_RS01940	COG1473	amidohydrolase
NYR48_RS01945	COG2079	MmgE PrpD family protein
NYR48_RS01955	COG1136	(ABC) transporter
NYR48_RS01960	COG0577	efflux transmembrane transporter activity
NYR48_RS01965	COG0745	RESPONSE REGULATOR receiver
NYR48_RS01970	COG3850	Histidine kinase
NYR48_RS01970	COG5002	protein histidine kinase activity
NYR48_RS01975	COG0457	Tetratricopeptide repeat
NYR48_RS01990	COG0527	aspartate kinase activity
NYR48_RS01995	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYR48_RS02000	COG4605	iron ion homeostasis
NYR48_RS02005	COG4604	ABC transporter, ATP-binding protein
NYR48_RS02010	COG4607	ABC-type enterochelin transport system periplasmic component
NYR48_RS02015	COG2814	Major facilitator Superfamily
NYR48_RS02020	COG1309	transcriptional regulator
NYR48_RS02025	COG0778	Nitroreductase
NYR48_RS02030	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NYR48_RS02035	COG0640	Transcriptional regulator
NYR48_RS02040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYR48_RS02045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NYR48_RS02050	COG1012	belongs to the aldehyde dehydrogenase family
NYR48_RS02055	COG4975	Glucose uptake
NYR48_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS02065	COG4549	nuclear export factor GLE1
NYR48_RS02070	COG1276	copper resistance
NYR48_RS02070	COG2372	response to copper ion
NYR48_RS02075	COG1349	DNA-binding transcription factor activity
NYR48_RS02085	COG2213	PTS system mannitol-specific
NYR48_RS02090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NYR48_RS02100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NYR48_RS02110	COG0561	phosphatase activity
NYR48_RS02120	COG1914	H( )-stimulated, divalent metal cation uptake system
NYR48_RS02130	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NYR48_RS02135	COG1984	allophanate hydrolase subunit 2
NYR48_RS02140	COG1414	Transcriptional regulator
NYR48_RS02145	COG2755	lipolytic protein G-D-S-L family
NYR48_RS02155	COG2329	Antibiotic biosynthesis monooxygenase
NYR48_RS02160	COG0768	penicillin binding
NYR48_RS02165	COG4989	oxidoreductase activity
NYR48_RS02170	COG3711	transcriptional antiterminator
NYR48_RS02175	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS02185	COG1917	Cupin 2, conserved barrel domain protein
NYR48_RS02190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NYR48_RS02195	COG3871	stress protein (general stress protein 26)
NYR48_RS02210	COG2814	Major facilitator Superfamily
NYR48_RS02215	COG1522	sequence-specific DNA binding
NYR48_RS02220	COG0551	DNA topoisomerase type I activity
NYR48_RS02220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NYR48_RS02225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NYR48_RS02230	COG3706	GGDEF domain
NYR48_RS02235	COG5298	Protein conserved in bacteria
NYR48_RS02240	COG1215	transferase activity, transferring glycosyl groups
NYR48_RS02250	COG0531	amino acid
NYR48_RS02255	COG0494	nUDIX hydrolase
NYR48_RS02260	COG0028	Belongs to the TPP enzyme family
NYR48_RS02285	COG1914	H( )-stimulated, divalent metal cation uptake system
NYR48_RS02305	COG2076	Multidrug Resistance protein
NYR48_RS02310	COG2217	Heavy metal translocating P-type atpase
NYR48_RS02315	COG3729	General stress protein
NYR48_RS02320	COG0662	Cupin 2, conserved barrel domain protein
NYR48_RS02325	COG2329	Antibiotic biosynthesis monooxygenase
NYR48_RS02330	COG3546	catalase activity
NYR48_RS02335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NYR48_RS02340	COG3290	protein histidine kinase activity
NYR48_RS02345	COG4565	transcriptional regulatory protein
NYR48_RS02350	COG1301	dicarboxylic acid transport
NYR48_RS02355	COG0628	permease
NYR48_RS02360	COG1131	(ABC) transporter
NYR48_RS02365	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NYR48_RS02375	COG1960	acyl-CoA dehydrogenase activity
NYR48_RS02390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NYR48_RS02395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYR48_RS02405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NYR48_RS02410	COG0513	Belongs to the DEAD box helicase family
NYR48_RS02415	COG3402	PFAM membrane-flanked domain
NYR48_RS02420	COG3428	Bacterial PH domain
NYR48_RS02425	COG0705	Rhomboid family
NYR48_RS02435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NYR48_RS02440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NYR48_RS02445	COG0864	Transcriptional regulator
NYR48_RS02450	COG2337	Toxic component of a toxin-antitoxin (TA) module
NYR48_RS02455	COG1366	Belongs to the anti-sigma-factor antagonist family
NYR48_RS02460	COG1366	Belongs to the anti-sigma-factor antagonist family
NYR48_RS02465	COG2172	sigma factor antagonist activity
NYR48_RS02470	COG2208	phosphoserine phosphatase activity
NYR48_RS02475	COG1366	Belongs to the anti-sigma-factor antagonist family
NYR48_RS02485	COG1191	sigma factor activity
NYR48_RS02490	COG2208	phosphoserine phosphatase activity
NYR48_RS02495	COG2183	response to ionizing radiation
NYR48_RS02545	COG2249	NAD(P)H dehydrogenase (quinone) activity
NYR48_RS02555	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NYR48_RS02560	COG1522	sequence-specific DNA binding
NYR48_RS02585	COG0477	Major facilitator Superfamily
NYR48_RS02595	COG1764	response to oxidative stress
NYR48_RS02600	COG1846	Transcriptional regulator
NYR48_RS02610	COG2030	dehydratase
NYR48_RS02620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NYR48_RS02625	COG1959	2 iron, 2 sulfur cluster binding
NYR48_RS02630	COG2910	NAD(P)H-binding
NYR48_RS02645	COG1278	Cold shock
NYR48_RS02650	COG1329	Transcriptional regulator
NYR48_RS02655	COG1937	Protein conserved in bacteria
NYR48_RS02660	COG2210	Belongs to the sulfur carrier protein TusA family
NYR48_RS02670	COG0425	Belongs to the sulfur carrier protein TusA family
NYR48_RS02670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NYR48_RS02680	COG0425	Belongs to the sulfur carrier protein TusA family
NYR48_RS02685	COG0730	response to heat
NYR48_RS02690	COG1794	racemase activity, acting on amino acids and derivatives
NYR48_RS02705	COG0583	DNA-binding transcription factor activity
NYR48_RS02710	COG0114	fumarate hydratase activity
NYR48_RS02715	COG3621	Patatin-like phospholipase
NYR48_RS02725	COG0662	Cupin 2, conserved barrel domain protein
NYR48_RS02730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NYR48_RS02740	COG0251	oxidation-reduction process
NYR48_RS02745	COG0814	amino acid
NYR48_RS02750	COG1473	amidohydrolase
NYR48_RS02755	COG1917	Cupin 2, conserved barrel domain protein
NYR48_RS02755	COG2207	Transcriptional regulator
NYR48_RS02765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYR48_RS02770	COG0477	Major facilitator Superfamily
NYR48_RS02790	COG0277	FAD linked oxidase domain protein
NYR48_RS02800	COG3764	Sortase (surface protein transpeptidase)
NYR48_RS02825	COG0662	Cupin 2, conserved barrel domain protein
NYR48_RS02830	COG2318	DinB family
NYR48_RS02835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NYR48_RS02870	COG0351	phosphomethylpyrimidine kinase
NYR48_RS02885	COG1064	alcohol dehydrogenase
NYR48_RS02890	COG0789	Transcriptional regulator
NYR48_RS02900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYR48_RS02935	COG2814	Major facilitator Superfamily
NYR48_RS02940	COG1309	transcriptional regulator
NYR48_RS02945	COG0697	spore germination
NYR48_RS02950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYR48_RS02955	COG5577	PFAM Coat F domain
NYR48_RS02965	COG1063	alcohol dehydrogenase
NYR48_RS02970	COG5577	PFAM Coat F domain
NYR48_RS02980	COG0738	Major facilitator superfamily
NYR48_RS02990	COG0110	maltose O-acetyltransferase activity
NYR48_RS02995	COG4585	Histidine kinase
NYR48_RS03000	COG2197	response regulator
NYR48_RS03005	COG2409	Drug exporters of the RND superfamily
NYR48_RS03010	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NYR48_RS03015	COG0488	(ABC) transporter
NYR48_RS03020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NYR48_RS03025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NYR48_RS03035	COG2814	Major facilitator Superfamily
NYR48_RS03040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYR48_RS03050	COG0730	response to heat
NYR48_RS03055	COG0456	acetyltransferase
NYR48_RS03065	COG1051	belongs to the nudix hydrolase family
NYR48_RS03070	COG2226	methyltransferase
NYR48_RS03075	COG0473	3-isopropylmalate dehydrogenase activity
NYR48_RS03080	COG1802	Transcriptional regulator
NYR48_RS03085	COG1819	glycosyl
NYR48_RS03100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NYR48_RS03110	COG1388	LysM domain
NYR48_RS03115	COG2814	Major facilitator Superfamily
NYR48_RS03120	COG2188	Transcriptional regulator
NYR48_RS03125	COG2186	Transcriptional regulator
NYR48_RS03130	COG2807	transmembrane transport
NYR48_RS03135	COG2076	Multidrug Resistance protein
NYR48_RS03140	COG2076	Multidrug Resistance protein
NYR48_RS03145	COG1309	transcriptional regulator
NYR48_RS03150	COG0531	amino acid
NYR48_RS03160	COG3832	glyoxalase III activity
NYR48_RS03165	COG0604	alcohol dehydrogenase
NYR48_RS03170	COG2814	Major facilitator Superfamily
NYR48_RS03210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NYR48_RS03215	COG0802	atpase or kinase
NYR48_RS03220	COG1214	PFAM Peptidase M22, glycoprotease
NYR48_RS03225	COG0456	acetyltransferase
NYR48_RS03230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NYR48_RS03235	COG0488	(ABC) transporter
NYR48_RS03250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NYR48_RS03255	COG0805	protein transport
NYR48_RS03265	COG1266	CAAX protease self-immunity
NYR48_RS03285	COG0457	Tetratricopeptide repeat
NYR48_RS03290	COG1063	alcohol dehydrogenase
NYR48_RS03295	COG2211	Major facilitator Superfamily
NYR48_RS03300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NYR48_RS03310	COG1842	Phage shock protein A
NYR48_RS03315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NYR48_RS03320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NYR48_RS03325	COG4260	virion core protein, lumpy skin disease virus
NYR48_RS03330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NYR48_RS03330	COG2755	lipolytic protein G-D-S-L family
NYR48_RS03345	COG1595	DNA-templated transcription, initiation
NYR48_RS03350	COG1063	alcohol dehydrogenase
NYR48_RS03355	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NYR48_RS03360	COG0823	Involved in the tonB-independent uptake of proteins
NYR48_RS03375	COG2132	Multicopper oxidase
NYR48_RS03380	COG1113	amino acid transport
NYR48_RS03385	COG0714	Associated with various cellular activities
NYR48_RS03390	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NYR48_RS03395	COG1305	Transglutaminase-like
NYR48_RS03405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NYR48_RS03410	COG1917	Cupin 2, conserved barrel domain protein
NYR48_RS03410	COG2207	Transcriptional regulator
NYR48_RS03415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NYR48_RS03435	COG2252	PERMEase
NYR48_RS03440	COG3064	Membrane
NYR48_RS03460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NYR48_RS03465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NYR48_RS03470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NYR48_RS03475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NYR48_RS03480	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NYR48_RS03495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NYR48_RS03505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NYR48_RS03510	COG0138	bifunctional purine biosynthesis protein purh
NYR48_RS03515	COG0151	Belongs to the GarS family
NYR48_RS03525	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NYR48_RS03530	COG1470	cell adhesion involved in biofilm formation
NYR48_RS03535	COG4496	protein, YerC YecD
NYR48_RS03540	COG0069	glutamate synthase activity
NYR48_RS03550	COG0210	DNA helicase
NYR48_RS03560	COG4851	CamS sex pheromone cAM373 precursor
NYR48_RS03565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NYR48_RS03570	COG1285	pathogenesis
NYR48_RS03575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NYR48_RS03595	COG1309	transcriptional regulator
NYR48_RS03600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NYR48_RS03605	COG1597	lipid kinase activity
NYR48_RS03610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NYR48_RS03620	COG1131	(ABC) transporter
NYR48_RS03660	COG5444	nuclease activity
NYR48_RS03690	COG3546	catalase activity
NYR48_RS03695	COG0454	-acetyltransferase
NYR48_RS03705	COG2323	membrane
NYR48_RS03715	COG2329	Antibiotic biosynthesis monooxygenase
NYR48_RS03720	COG0346	lactoylglutathione lyase activity
NYR48_RS03725	COG1366	Belongs to the anti-sigma-factor antagonist family
NYR48_RS03730	COG5583	Uncharacterized small protein (DUF2292)
NYR48_RS03735	COG0196	riboflavin kinase activity
NYR48_RS03740	COG0670	Belongs to the BI1 family
NYR48_RS03745	COG1846	Transcriptional regulator
NYR48_RS03750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NYR48_RS03760	COG2124	cytochrome p450
NYR48_RS03760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NYR48_RS03775	COG1131	(ABC) transporter
NYR48_RS03820	COG4106	trans-aconitate 2-methyltransferase activity
NYR48_RS03825	COG1368	sulfuric ester hydrolase activity
NYR48_RS03830	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NYR48_RS03835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYR48_RS03840	COG1442	glycosyl transferase family 8
NYR48_RS03845	COG1216	Glycosyl transferase, family 2
NYR48_RS03850	COG1442	glycosyl transferase family 8
NYR48_RS03855	COG2223	nitrite transmembrane transporter activity
NYR48_RS03860	COG0531	amino acid
NYR48_RS03865	COG1012	belongs to the aldehyde dehydrogenase family
NYR48_RS03870	COG0840	transmembrane signaling receptor activity
NYR48_RS03875	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS03880	COG0457	Tetratricopeptide repeat
NYR48_RS03880	COG0463	Glycosyl transferase, family 2
NYR48_RS03885	COG0488	(ABC) transporter
NYR48_RS03890	COG0789	Transcriptional regulator
NYR48_RS03895	COG2814	Major facilitator Superfamily
NYR48_RS03900	COG0488	(ABC) transporter
NYR48_RS03905	COG0513	Belongs to the DEAD box helicase family
NYR48_RS03910	COG0456	acetyltransferase
NYR48_RS03915	COG2130	NADP-dependent
NYR48_RS03930	COG3866	Pectate lyase
NYR48_RS03935	COG0471	metal ion transport
NYR48_RS03970	COG0745	RESPONSE REGULATOR receiver
NYR48_RS03970	COG2972	Histidine kinase
NYR48_RS03980	COG3279	Response regulator of the LytR AlgR family
NYR48_RS03990	COG3764	Sortase (surface protein transpeptidase)
NYR48_RS03995	COG3290	protein histidine kinase activity
NYR48_RS04000	COG4565	transcriptional regulatory protein
NYR48_RS04005	COG3181	Tripartite tricarboxylate transporter family receptor
NYR48_RS04010	COG2851	Citrate transporter
NYR48_RS04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NYR48_RS04020	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NYR48_RS04030	COG2258	MOSC domain
NYR48_RS04050	COG0024	Methionine aminopeptidase
NYR48_RS04055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NYR48_RS04055	COG1263	PTS System
NYR48_RS04065	COG1368	sulfuric ester hydrolase activity
NYR48_RS04075	COG0071	Belongs to the small heat shock protein (HSP20) family
NYR48_RS04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NYR48_RS04090	COG1263	PTS System
NYR48_RS04095	COG0366	Alpha amylase catalytic
NYR48_RS04100	COG2188	Transcriptional regulator
NYR48_RS04105	COG0778	Nitroreductase
NYR48_RS04120	COG0737	Belongs to the 5'-nucleotidase family
NYR48_RS04125	COG0693	protein deglycase activity
NYR48_RS04130	COG1609	Transcriptional regulator
NYR48_RS04145	COG2814	Major facilitator Superfamily
NYR48_RS04155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NYR48_RS04160	COG4980	gas vesicle protein
NYR48_RS04165	COG1295	ribonuclease BN
NYR48_RS04170	COG0477	Major facilitator Superfamily
NYR48_RS04175	COG0387	Pfam Sodium calcium exchanger
NYR48_RS04185	COG0668	transmembrane transport
NYR48_RS04190	COG0535	radical SAM domain protein
NYR48_RS04200	COG0726	polysaccharide deacetylase
NYR48_RS04205	COG2084	Dehydrogenase
NYR48_RS04215	COG0598	Magnesium transport protein CorA
NYR48_RS04220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NYR48_RS04225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NYR48_RS04235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NYR48_RS04240	COG4637	Psort location Cytoplasmic, score
NYR48_RS04245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NYR48_RS04250	COG0022	dehydrogenase e1 component
NYR48_RS04255	COG0508	dehydrogenase complex catalyzes the overall conversion of
NYR48_RS04260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NYR48_RS04265	COG3284	Transcriptional regulator
NYR48_RS04275	COG1486	melibiose metabolic process
NYR48_RS04280	COG1737	Transcriptional regulator
NYR48_RS04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NYR48_RS04285	COG1263	PTS System
NYR48_RS04290	COG5434	Belongs to the glycosyl hydrolase 28 family
NYR48_RS04295	COG1132	(ABC) transporter
NYR48_RS04300	COG1132	(ABC) transporter
NYR48_RS04305	COG2259	Doxx family
NYR48_RS04310	COG2514	catechol 2,3-dioxygenase activity
NYR48_RS04320	COG1695	Transcriptional regulator
NYR48_RS04325	COG2249	NAD(P)H dehydrogenase (quinone) activity
NYR48_RS04330	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NYR48_RS04335	COG3848	Pyruvate phosphate dikinase
NYR48_RS04335	COG0574	Belongs to the PEP-utilizing enzyme family
NYR48_RS04340	COG2732	(Barnase) inhibitor
NYR48_RS04345	COG2318	DinB family
NYR48_RS04350	COG2814	Major facilitator Superfamily
NYR48_RS04355	COG1846	Transcriptional regulator
NYR48_RS04360	COG0392	lysyltransferase activity
NYR48_RS04360	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NYR48_RS04365	COG0384	phenazine biosynthesis protein PhzF
NYR48_RS04370	COG0778	Nitroreductase
NYR48_RS04385	COG1090	epimerase
NYR48_RS04400	COG2814	Major facilitator Superfamily
NYR48_RS04410	COG3591	Belongs to the peptidase S1B family
NYR48_RS04425	COG3103	Sh3 type 3 domain protein
NYR48_RS04430	COG5658	integral membrane protein
NYR48_RS04435	COG0596	Alpha beta hydrolase
NYR48_RS04440	COG0463	Glycosyl transferase, family 2
NYR48_RS04445	COG4485	Bacterial membrane protein, YfhO
NYR48_RS04450	COG1988	membrane-bound metal-dependent
NYR48_RS04455	COG1194	a g-specific adenine glycosylase
NYR48_RS04465	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS04485	COG1132	(ABC) transporter
NYR48_RS04490	COG4129	membrane
NYR48_RS04500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NYR48_RS04505	COG0735	belongs to the Fur family
NYR48_RS04615	COG1757	Na H antiporter
NYR48_RS04630	COG0277	FAD linked oxidase domain protein
NYR48_RS04640	COG0747	negative chemotaxis
NYR48_RS04645	COG0601	transmembrane transport
NYR48_RS04650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NYR48_RS04655	COG0444	Belongs to the ABC transporter superfamily
NYR48_RS04660	COG4608	Belongs to the ABC transporter superfamily
NYR48_RS04665	COG0753	catalase activity
NYR48_RS04675	COG1116	anion transmembrane transporter activity
NYR48_RS04680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NYR48_RS04685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NYR48_RS04705	COG1476	TRANSCRIPTIONal
NYR48_RS04715	COG3382	B3 4 domain protein
NYR48_RS04720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NYR48_RS04730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NYR48_RS04735	COG0789	Transcriptional regulator
NYR48_RS04740	COG1664	Polymer-forming cytoskeletal
NYR48_RS04745	COG1664	Polymer-forming cytoskeletal
NYR48_RS04750	COG2766	serine protein kinase
NYR48_RS04760	COG1846	Transcriptional regulator
NYR48_RS04765	COG1566	PFAM secretion protein HlyD family protein
NYR48_RS04770	COG2814	Major facilitator Superfamily
NYR48_RS04775	COG0655	NAD(P)H dehydrogenase (quinone) activity
NYR48_RS04790	COG1725	Transcriptional regulator
NYR48_RS04795	COG1131	(ABC) transporter
NYR48_RS04800	COG1131	(ABC) transporter
NYR48_RS04805	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NYR48_RS04810	COG1278	Cold shock
NYR48_RS04815	COG1464	Belongs to the NlpA lipoprotein family
NYR48_RS04820	COG3706	GGDEF domain
NYR48_RS04825	COG1823	symporter activity
NYR48_RS04835	COG5006	permease, DMT superfamily
NYR48_RS04860	COG5577	PFAM Coat F domain
NYR48_RS04865	COG0737	Belongs to the 5'-nucleotidase family
NYR48_RS04865	COG1525	nuclease
NYR48_RS04865	COG4085	toxin activity
NYR48_RS04870	COG3764	Sortase (surface protein transpeptidase)
NYR48_RS04875	COG0564	pseudouridine synthase activity
NYR48_RS04885	COG0517	IMP dehydrogenase activity
NYR48_RS04890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NYR48_RS04895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NYR48_RS04895	COG3153	acetyltransferase
NYR48_RS04905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NYR48_RS04910	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NYR48_RS04915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NYR48_RS04925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NYR48_RS04930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NYR48_RS04935	COG2203	Gaf domain
NYR48_RS04935	COG4585	Histidine kinase
NYR48_RS04940	COG2197	response regulator
NYR48_RS04945	COG0431	NADPH-dependent FMN reductase
NYR48_RS04960	COG1388	LysM domain
NYR48_RS04960	COG0791	NLP P60 protein
NYR48_RS04965	COG1959	2 iron, 2 sulfur cluster binding
NYR48_RS04975	COG2719	SpoVR family
NYR48_RS04980	COG1785	Belongs to the alkaline phosphatase family
NYR48_RS04985	COG0791	NLP P60 protein
NYR48_RS04985	COG1388	LysM domain
NYR48_RS04990	COG0583	DNA-binding transcription factor activity
NYR48_RS04995	COG0372	Belongs to the citrate synthase family
NYR48_RS05000	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS05005	COG0531	amino acid
NYR48_RS05010	COG0733	neurotransmitter:sodium symporter activity
NYR48_RS05025	COG1595	DNA-templated transcription, initiation
NYR48_RS05030	COG0204	Acyl-transferase
NYR48_RS05035	COG1253	flavin adenine dinucleotide binding
NYR48_RS05040	COG0789	Transcriptional regulator
NYR48_RS05045	COG0436	Aminotransferase
NYR48_RS05050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYR48_RS05055	COG1253	flavin adenine dinucleotide binding
NYR48_RS05060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NYR48_RS05065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NYR48_RS05070	COG0584	glycerophosphoryl diester phosphodiesterase
NYR48_RS05080	COG0668	transmembrane transport
NYR48_RS05085	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NYR48_RS05090	COG0726	polysaccharide deacetylase
NYR48_RS05095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NYR48_RS05100	COG3226	Transcriptional regulator
NYR48_RS05110	COG0589	response to stress
NYR48_RS05115	COG1132	(ABC) transporter
NYR48_RS05120	COG1132	(ABC) transporter
NYR48_RS05125	COG0702	epimerase
NYR48_RS05145	COG0189	ligase activity
NYR48_RS05150	COG0189	ligase activity
NYR48_RS05165	COG4335	DNA alkylation repair
NYR48_RS05170	COG0561	phosphatase activity
NYR48_RS05175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NYR48_RS05185	COG0475	glutathione-regulated potassium exporter activity
NYR48_RS05190	COG0490	domain, Protein
NYR48_RS05200	COG1024	Enoyl-CoA hydratase
NYR48_RS05210	COG4152	abc transporter atp-binding protein
NYR48_RS05215	COG1668	transmembrane transport
NYR48_RS05220	COG0420	3'-5' exonuclease activity
NYR48_RS05225	COG4717	serine-type aminopeptidase activity
NYR48_RS05240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NYR48_RS05275	COG4980	gas vesicle protein
NYR48_RS05290	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NYR48_RS05295	COG0537	adenosine 5'-monophosphoramidase activity
NYR48_RS05300	COG1131	(ABC) transporter
NYR48_RS05305	COG4473	ABC transporter
NYR48_RS05315	COG1473	amidohydrolase
NYR48_RS05320	COG3069	C4-dicarboxylate transmembrane transporter activity
NYR48_RS05325	COG2329	Antibiotic biosynthesis monooxygenase
NYR48_RS05330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NYR48_RS05340	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NYR48_RS05345	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NYR48_RS05350	COG1309	transcriptional regulator
NYR48_RS05355	COG1511	domain protein
NYR48_RS05360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYR48_RS05370	COG1363	Peptidase, m42
NYR48_RS05375	COG1301	dicarboxylic acid transport
NYR48_RS05385	COG1234	tRNA 3'-trailer cleavage
NYR48_RS05390	COG0095	Lipoate-protein ligase
NYR48_RS05395	COG0702	epimerase
NYR48_RS05400	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS05410	COG0501	Belongs to the peptidase M48B family
NYR48_RS05415	COG1404	Belongs to the peptidase S8 family
NYR48_RS05420	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NYR48_RS05425	COG0406	alpha-ribazole phosphatase activity
NYR48_RS05430	COG0183	Belongs to the thiolase family
NYR48_RS05435	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS05440	COG1268	BioY protein
NYR48_RS05445	COG0840	transmembrane signaling receptor activity
NYR48_RS05450	COG0723	plastoquinol--plastocyanin reductase activity
NYR48_RS05450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NYR48_RS05455	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS05465	COG4903	ComK protein
NYR48_RS05475	COG5646	InterPro IPR014922
NYR48_RS05500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NYR48_RS05515	COG0398	Pfam SNARE associated Golgi protein
NYR48_RS05520	COG0681	Belongs to the peptidase S26 family
NYR48_RS05525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NYR48_RS05530	COG1846	Transcriptional regulator
NYR48_RS05535	COG3180	Ammonia monooxygenase
NYR48_RS05540	COG2814	Major facilitator Superfamily
NYR48_RS05550	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NYR48_RS05555	COG2323	membrane
NYR48_RS05570	COG0420	3'-5' exonuclease activity
NYR48_RS05575	COG0419	ATPase involved in DNA repair
NYR48_RS05580	COG1403	HNH endonuclease
NYR48_RS05620	COG0179	Fumarylacetoacetate (FAA) hydrolase
NYR48_RS05635	COG0367	asparagine synthase
NYR48_RS05640	COG1562	ergosterol biosynthetic process
NYR48_RS05645	COG0534	Mate efflux family protein
NYR48_RS05650	COG1917	Cupin 2, conserved barrel domain protein
NYR48_RS05650	COG2207	Transcriptional regulator
NYR48_RS05655	COG2318	DinB family
NYR48_RS05660	COG1279	arginine transmembrane transporter activity
NYR48_RS05670	COG1357	PFAM Pentapeptide repeats (8 copies)
NYR48_RS05675	COG2153	protein acetylation
NYR48_RS05680	COG0646	methionine synthase
NYR48_RS05680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NYR48_RS05690	COG2996	Protein conserved in bacteria
NYR48_RS05695	COG1744	ABC transporter substrate-binding protein PnrA-like
NYR48_RS05700	COG0840	transmembrane signaling receptor activity
NYR48_RS05705	COG2124	cytochrome p450
NYR48_RS05715	COG1307	EDD domain protein, DegV family
NYR48_RS05720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NYR48_RS05740	COG0561	phosphatase activity
NYR48_RS05745	COG1073	alpha beta
NYR48_RS05750	COG2151	metal-sulfur cluster biosynthetic enzyme
NYR48_RS05760	COG0277	FAD linked oxidase domain protein
NYR48_RS05765	COG2271	Major facilitator Superfamily
NYR48_RS05775	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NYR48_RS05785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NYR48_RS05790	COG0505	Belongs to the CarA family
NYR48_RS05795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NYR48_RS05800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NYR48_RS05815	COG2267	carboxylic ester hydrolase activity
NYR48_RS05825	COG1744	ABC transporter substrate-binding protein PnrA-like
NYR48_RS05840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYR48_RS05845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYR48_RS05850	COG5504	Zn-dependent protease
NYR48_RS05855	COG0444	Belongs to the ABC transporter superfamily
NYR48_RS05860	COG4608	Belongs to the ABC transporter superfamily
NYR48_RS05870	COG0601	transmembrane transport
NYR48_RS05875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NYR48_RS05885	COG0180	Tryptophanyl-tRNA synthetase
NYR48_RS05890	COG4166	transmembrane transport
NYR48_RS05895	COG0601	transmembrane transport
NYR48_RS05900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NYR48_RS05905	COG0444	Belongs to the ABC transporter superfamily
NYR48_RS05910	COG4608	Belongs to the ABC transporter superfamily
NYR48_RS05920	COG0456	acetyltransferase
NYR48_RS05925	COG1393	Belongs to the ArsC family
NYR48_RS05930	COG0861	Integral membrane protein TerC family
NYR48_RS05935	COG4862	establishment of competence for transformation
NYR48_RS05940	COG4469	Competence protein
NYR48_RS05945	COG1164	Oligoendopeptidase f
NYR48_RS05955	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NYR48_RS05960	COG2346	COG2346, Truncated hemoglobins
NYR48_RS05965	COG0741	lytic transglycosylase activity
NYR48_RS05970	COG4116	CYTH
NYR48_RS05980	COG2357	RelA SpoT domain protein
NYR48_RS05985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NYR48_RS05990	COG0564	pseudouridine synthase activity
NYR48_RS06000	COG0475	glutathione-regulated potassium exporter activity
NYR48_RS06000	COG0569	domain protein
NYR48_RS06005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NYR48_RS06010	COG0352	thiamine-phosphate diphosphorylase activity
NYR48_RS06015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NYR48_RS06020	COG2104	thiamine diphosphate biosynthetic process
NYR48_RS06030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NYR48_RS06035	COG0351	phosphomethylpyrimidine kinase
NYR48_RS06040	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NYR48_RS06095	COG0210	DNA helicase
NYR48_RS06115	COG1131	(ABC) transporter
NYR48_RS06125	COG2153	protein acetylation
NYR48_RS06135	COG2382	esterase
NYR48_RS06140	COG0626	cystathionine gamma-synthase activity
NYR48_RS06145	COG0626	cystathionine gamma-synthase activity
NYR48_RS06155	COG0582	viral genome integration into host DNA
NYR48_RS06160	COG2856	Zn peptidase
NYR48_RS06170	COG1396	sequence-specific DNA binding
NYR48_RS06215	COG3935	DnaD domain protein
NYR48_RS06220	COG1484	DNA-dependent DNA replication
NYR48_RS06280	COG1595	DNA-templated transcription, initiation
NYR48_RS06300	COG5484	DNA packaging
NYR48_RS06415	COG4824	toxin secretion phage lysis holin
NYR48_RS06460	COG5444	nuclease activity
NYR48_RS06485	COG1595	DNA-templated transcription, initiation
NYR48_RS06510	COG2367	Beta-lactamase
NYR48_RS06515	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NYR48_RS06525	COG1846	Transcriptional regulator
NYR48_RS06535	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NYR48_RS06540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NYR48_RS06545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NYR48_RS06550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NYR48_RS06550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NYR48_RS06555	COG1447	Phosphotransferase system cellobiose-specific component IIA
NYR48_RS06585	COG1285	pathogenesis
NYR48_RS06595	COG2205	protein histidine kinase activity
NYR48_RS06605	COG3383	formate dehydrogenase (NAD+) activity
NYR48_RS06610	COG2427	Protein of unknown function (DUF1641)
NYR48_RS06615	COG2124	cytochrome p450
NYR48_RS06620	COG1819	glycosyl
NYR48_RS06630	COG1587	Uroporphyrinogen-III synthase
NYR48_RS06635	COG0390	transport system, permease component
NYR48_RS06640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NYR48_RS06645	COG0697	spore germination
NYR48_RS06650	COG4297	protein containing double-stranded beta helix domain
NYR48_RS06660	COG1252	NADH dehydrogenase
NYR48_RS06670	COG2211	Major facilitator Superfamily
NYR48_RS06675	COG1609	Transcriptional regulator
NYR48_RS06680	COG0246	Mannitol dehydrogenase
NYR48_RS06685	COG2721	sulfolactate sulfo-lyase activity
NYR48_RS06690	COG0730	response to heat
NYR48_RS06695	COG2318	DinB family
NYR48_RS06700	COG0457	Tetratricopeptide repeat
NYR48_RS06710	COG1388	LysM domain
NYR48_RS06710	COG3409	Peptidoglycan-binding domain 1 protein
NYR48_RS06710	COG5632	N-Acetylmuramoyl-L-alanine amidase
NYR48_RS06720	COG4195	phage-related replication protein
NYR48_RS06725	COG2856	Zn peptidase
NYR48_RS06730	COG1396	sequence-specific DNA binding
NYR48_RS06740	COG1522	sequence-specific DNA binding
NYR48_RS06745	COG1484	DNA-dependent DNA replication
NYR48_RS06765	COG1595	DNA-templated transcription, initiation
NYR48_RS06770	COG3728	DNA packaging
NYR48_RS06770	COG5484	DNA packaging
NYR48_RS06775	COG1783	phage Terminase large subunit
NYR48_RS06780	COG5518	Phage portal protein
NYR48_RS06785	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NYR48_RS06790	COG4653	Phage capsid family
NYR48_RS06840	COG3953	SLT domain
NYR48_RS06840	COG3953	SLT domain
NYR48_RS06840	COG3953	SLT domain
NYR48_RS06840	COG5412	phage tail tape measure protein
NYR48_RS06840	COG5412	phage tail tape measure protein
NYR48_RS06840	COG5412	phage tail tape measure protein
NYR48_RS06845	COG1652	LysM domain
NYR48_RS06850	COG4193	domain, Protein
NYR48_RS06860	COG3628	GPW Gp25 family protein
NYR48_RS06865	COG3299	homolog of phage Mu protein gp47
NYR48_RS06870	COG3778	Protein conserved in bacteria
NYR48_RS06910	COG5632	N-Acetylmuramoyl-L-alanine amidase
NYR48_RS06910	COG3409	Peptidoglycan-binding domain 1 protein
NYR48_RS06930	COG0306	phosphate transporter
NYR48_RS06935	COG1392	Phosphate transport regulator
NYR48_RS06940	COG0531	amino acid
NYR48_RS06945	COG0346	lactoylglutathione lyase activity
NYR48_RS06950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NYR48_RS06955	COG0463	Glycosyl transferase, family 2
NYR48_RS06965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NYR48_RS06970	COG0477	Major facilitator Superfamily
NYR48_RS06975	COG2362	D-Aminopeptidase
NYR48_RS06980	COG0601	transmembrane transport
NYR48_RS06985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NYR48_RS06990	COG0444	Belongs to the ABC transporter superfamily
NYR48_RS06995	COG4166	transmembrane transport
NYR48_RS07000	COG1619	proteins homologs of microcin C7 resistance protein MccF
NYR48_RS07005	COG4948	Mandelate Racemase Muconate Lactonizing
NYR48_RS07010	COG0791	NLP P60 protein
NYR48_RS07015	COG4608	Belongs to the ABC transporter superfamily
NYR48_RS07020	COG2706	6-phosphogluconolactonase activity
NYR48_RS07025	COG1834	amidinotransferase
NYR48_RS07030	COG1607	acyl-coa hydrolase
NYR48_RS07035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NYR48_RS07040	COG2076	Multidrug Resistance protein
NYR48_RS07045	COG2076	Multidrug Resistance protein
NYR48_RS07050	COG0788	formyltetrahydrofolate deformylase activity
NYR48_RS07055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NYR48_RS07065	COG1764	response to oxidative stress
NYR48_RS07070	COG1846	Transcriptional regulator
NYR48_RS07075	COG1764	response to oxidative stress
NYR48_RS07090	COG0463	Glycosyl transferase, family 2
NYR48_RS07090	COG0457	Tetratricopeptide repeat
NYR48_RS07100	COG2814	Major facilitator Superfamily
NYR48_RS07115	COG1404	Belongs to the peptidase S8 family
NYR48_RS07120	COG1366	Belongs to the anti-sigma-factor antagonist family
NYR48_RS07125	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NYR48_RS07130	COG1122	ATPase activity
NYR48_RS07135	COG4721	ABC-type cobalt transport system, permease component
NYR48_RS07140	COG1388	LysM domain
NYR48_RS07140	COG3858	chitin binding
NYR48_RS07150	COG2239	Acts as a magnesium transporter
NYR48_RS07155	COG0789	Transcriptional regulator
NYR48_RS07170	COG1846	Transcriptional regulator
NYR48_RS07175	COG0726	polysaccharide deacetylase
NYR48_RS07180	COG1793	dna ligase
NYR48_RS07180	COG3285	dna ligase
NYR48_RS07185	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NYR48_RS07190	COG0586	Pfam SNARE associated Golgi protein
NYR48_RS07200	COG1191	sigma factor activity
NYR48_RS07225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NYR48_RS07230	COG2323	membrane
NYR48_RS07240	COG3594	Acyltransferase
NYR48_RS07245	COG5002	protein histidine kinase activity
NYR48_RS07250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NYR48_RS07270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NYR48_RS07275	COG0436	Aminotransferase
NYR48_RS07305	COG3852	Histidine kinase
NYR48_RS07310	COG1846	Transcriptional regulator
NYR48_RS07315	COG1360	Flagellar Motor Protein
NYR48_RS07320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NYR48_RS07325	COG0542	response to heat
NYR48_RS07330	COG3949	Membrane
NYR48_RS07345	COG0720	synthase
NYR48_RS07350	COG0602	queuosine metabolic process
NYR48_RS07360	COG1733	regulation of RNA biosynthetic process
NYR48_RS07365	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS07385	COG4873	Protein conserved in bacteria
NYR48_RS07395	COG3773	Cell wall hydrolase
NYR48_RS07400	COG2244	polysaccharide biosynthetic process
NYR48_RS07405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYR48_RS07410	COG2217	Heavy metal translocating P-type atpase
NYR48_RS07415	COG0006	proline dipeptidase activity
NYR48_RS07425	COG1609	Transcriptional regulator
NYR48_RS07430	COG3711	transcriptional antiterminator
NYR48_RS07435	COG1263	PTS System
NYR48_RS07435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NYR48_RS07435	COG2190	(PTS) system
NYR48_RS07440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NYR48_RS07445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NYR48_RS07455	COG1533	DNA photolyase activity
NYR48_RS07460	COG0840	transmembrane signaling receptor activity
NYR48_RS07465	COG2084	Dehydrogenase
NYR48_RS07470	COG2340	Cysteine-rich secretory protein family
NYR48_RS07475	COG0768	penicillin binding
NYR48_RS07480	COG4191	Histidine kinase
NYR48_RS07485	COG0436	Aminotransferase
NYR48_RS07495	COG0784	Response regulator, receiver
NYR48_RS07495	COG0835	chemotaxis
NYR48_RS07505	COG2814	Major facilitator Superfamily
NYR48_RS07510	COG1376	ErfK ybiS ycfS ynhG family protein
NYR48_RS07515	COG1408	metallophosphoesterase
NYR48_RS07520	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS07530	COG2200	EAL domain
NYR48_RS07535	COG4703	Protein of unknown function (DUF1797)
NYR48_RS07540	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NYR48_RS07550	COG0517	IMP dehydrogenase activity
NYR48_RS07555	COG0583	DNA-binding transcription factor activity
NYR48_RS07560	COG0716	FMN binding
NYR48_RS07570	COG0716	FMN binding
NYR48_RS07590	COG0668	transmembrane transport
NYR48_RS07595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYR48_RS07615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NYR48_RS07620	COG0303	'Molybdopterin
NYR48_RS07625	COG1763	Mo-molybdopterin cofactor biosynthetic process
NYR48_RS07630	COG0314	molybdopterin synthase activity
NYR48_RS07635	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NYR48_RS07645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NYR48_RS07650	COG1136	(ABC) transporter
NYR48_RS07655	COG0577	efflux transmembrane transporter activity
NYR48_RS07660	COG1349	DNA-binding transcription factor activity
NYR48_RS07665	COG1105	Belongs to the carbohydrate kinase PfkB family
NYR48_RS07670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NYR48_RS07670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NYR48_RS07670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NYR48_RS07675	COG0681	Belongs to the peptidase S26 family
NYR48_RS07685	COG0488	(ABC) transporter
NYR48_RS07690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NYR48_RS07695	COG2309	aminopeptidase activity
NYR48_RS07705	COG1077	Cell shape determining protein MreB Mrl
NYR48_RS07710	COG2002	toxin-antitoxin pair type II binding
NYR48_RS07715	COG3852	Histidine kinase
NYR48_RS07720	COG2105	PFAM AIG2 family protein
NYR48_RS07720	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NYR48_RS07725	COG0569	domain protein
NYR48_RS07735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NYR48_RS07745	COG0561	phosphatase activity
NYR48_RS07750	COG0242	peptide deformylase activity
NYR48_RS07760	COG0497	DNA recombination
NYR48_RS07770	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS07770	COG3321	synthase
NYR48_RS07770	COG4221	oxidoreductase activity
NYR48_RS07770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS07775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS07775	COG4221	oxidoreductase activity
NYR48_RS07775	COG3321	synthase
NYR48_RS07775	COG0300	oxidoreductase activity
NYR48_RS07780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS07780	COG3321	synthase
NYR48_RS07780	COG4221	oxidoreductase activity
NYR48_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS07785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS07785	COG0300	oxidoreductase activity
NYR48_RS07785	COG3321	synthase
NYR48_RS07785	COG4221	oxidoreductase activity
NYR48_RS07790	COG0300	oxidoreductase activity
NYR48_RS07790	COG3321	synthase
NYR48_RS07790	COG4221	oxidoreductase activity
NYR48_RS07790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS07795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS07795	COG3321	synthase
NYR48_RS07795	COG4221	oxidoreductase activity
NYR48_RS07795	COG0300	oxidoreductase activity
NYR48_RS07800	COG4221	oxidoreductase activity
NYR48_RS07800	COG3321	synthase
NYR48_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS07800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS07805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NYR48_RS07810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NYR48_RS07815	COG0022	dehydrogenase e1 component
NYR48_RS07820	COG0508	dehydrogenase complex catalyzes the overall conversion of
NYR48_RS07825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NYR48_RS07830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYR48_RS07845	COG1982	Orn Lys Arg decarboxylase major
NYR48_RS07865	COG0483	inositol monophosphate 1-phosphatase activity
NYR48_RS07875	COG3227	Zinc metalloprotease (Elastase)
NYR48_RS07880	COG1595	DNA-templated transcription, initiation
NYR48_RS07900	COG1217	gtp-binding protein TYPA
NYR48_RS07910	COG4896	Protein conserved in bacteria
NYR48_RS07920	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NYR48_RS07925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NYR48_RS07930	COG2066	Belongs to the glutaminase family
NYR48_RS07940	COG0772	Belongs to the SEDS family
NYR48_RS07945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NYR48_RS07960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NYR48_RS07960	COG2010	Cytochrome c
NYR48_RS07965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NYR48_RS07970	COG1845	cytochrome c oxidase, subunit III
NYR48_RS07975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NYR48_RS07980	COG3336	cytochrome c oxidase
NYR48_RS07990	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NYR48_RS07995	COG2340	Cysteine-rich secretory protein family
NYR48_RS08010	COG3679	Belongs to the UPF0342 family
NYR48_RS08025	COG0742	ribosomal rna small subunit methyltransferase
NYR48_RS08035	COG3314	Sporulation integral membrane protein YlbJ
NYR48_RS08040	COG1752	Esterase of the alpha-beta hydrolase superfamily
NYR48_RS08045	COG3480	Lon protease (S16) C-terminal proteolytic domain
NYR48_RS08055	COG1399	metal-binding, possibly nucleic acid-binding protein
NYR48_RS08075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NYR48_RS08095	COG4839	cell division protein FtsL
NYR48_RS08100	COG0768	penicillin binding
NYR48_RS08105	COG0768	penicillin binding
NYR48_RS08125	COG0772	Belongs to the SEDS family
NYR48_RS08140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NYR48_RS08145	COG0849	cell division
NYR48_RS08150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NYR48_RS08155	COG4412	M6 family metalloprotease domain protein
NYR48_RS08155	COG1404	Belongs to the peptidase S8 family
NYR48_RS08165	COG1191	sigma factor activity
NYR48_RS08170	COG1191	sigma factor activity
NYR48_RS08175	COG1119	ATPase activity
NYR48_RS08180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NYR48_RS08185	COG1873	PFAM PRC-barrel domain
NYR48_RS08190	COG1496	oxidoreductase activity
NYR48_RS08195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NYR48_RS08205	COG0762	integral membrane protein
NYR48_RS08210	COG2302	S4 RNA-binding domain
NYR48_RS08215	COG3599	regulation of cell shape
NYR48_RS08220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NYR48_RS08225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NYR48_RS08235	COG0564	pseudouridine synthase activity
NYR48_RS08245	COG2233	PERMEase
NYR48_RS08255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NYR48_RS08260	COG0505	Belongs to the CarA family
NYR48_RS08265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NYR48_RS08280	COG0284	orotidine-5'-phosphate decarboxylase activity
NYR48_RS08285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NYR48_RS08295	COG0306	phosphate transporter
NYR48_RS08310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NYR48_RS08315	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NYR48_RS08320	COG1648	precorrin-2 dehydrogenase activity
NYR48_RS08330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NYR48_RS08335	COG1561	YicC-like family, N-terminal region
NYR48_RS08345	COG0194	GDP metabolic process
NYR48_RS08355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NYR48_RS08360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NYR48_RS08365	COG0242	peptide deformylase activity
NYR48_RS08375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NYR48_RS08375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NYR48_RS08385	COG0631	protein serine/threonine phosphatase activity
NYR48_RS08390	COG0515	serine threonine protein kinase
NYR48_RS08390	COG2815	serine threonine protein kinase
NYR48_RS08400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NYR48_RS08405	COG1564	THIamine pyrophosphokinase
NYR48_RS08420	COG1302	Protein conserved in bacteria
NYR48_RS08425	COG1461	Dihydroxyacetone kinase
NYR48_RS08430	COG1760	l-serine dehydratase
NYR48_RS08435	COG1760	l-serine dehydratase
NYR48_RS08440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NYR48_RS08455	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NYR48_RS08460	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS08475	COG1196	nuclear chromosome segregation
NYR48_RS08480	COG0552	protein localization to endoplasmic reticulum
NYR48_RS08495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NYR48_RS08505	COG1837	Belongs to the UPF0109 family
NYR48_RS08530	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NYR48_RS08545	COG2257	FlhB HrpN YscU SpaS Family
NYR48_RS08555	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NYR48_RS08560	COG0758	DNA mediated transformation
NYR48_RS08565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NYR48_RS08575	COG4974	Belongs to the 'phage' integrase family
NYR48_RS08595	COG1815	bacterial-type flagellum-dependent cell motility
NYR48_RS08600	COG1558	bacterial-type flagellum-dependent cell motility
NYR48_RS08605	COG1677	Flagellar hook-basal body complex protein FliE
NYR48_RS08610	COG1766	The M ring may be actively involved in energy transduction
NYR48_RS08615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NYR48_RS08620	COG1317	bacterial-type flagellum organization
NYR48_RS08625	COG1157	protein secretion by the type III secretion system
NYR48_RS08630	COG2882	bacterial-type flagellum organization
NYR48_RS08635	COG3334	PFAM MgtE intracellular
NYR48_RS08640	COG3144	bacterial-type flagellum assembly
NYR48_RS08645	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NYR48_RS08650	COG4786	Flagellar basal body rod
NYR48_RS08655	COG1582	Flagellar protein (FlbD)
NYR48_RS08660	COG1580	Controls the rotational direction of flagella during chemotaxis
NYR48_RS08665	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NYR48_RS08670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NYR48_RS08670	COG1776	CheC inhibitor of MCP methylation
NYR48_RS08675	COG2201	protein-glutamate methylesterase activity
NYR48_RS08680	COG3190	flagellar
NYR48_RS08685	COG1338	Plays a role in the flagellum-specific transport system
NYR48_RS08690	COG1987	bacterial-type flagellum assembly
NYR48_RS08695	COG1684	flagellar biosynthetic protein fliR
NYR48_RS08700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NYR48_RS08705	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NYR48_RS08710	COG1419	protein localization to endoplasmic reticulum
NYR48_RS08715	COG0455	bacterial-type flagellum organization
NYR48_RS08720	COG2201	protein-glutamate methylesterase activity
NYR48_RS08725	COG0643	Histidine kinase
NYR48_RS08725	COG2198	Histidine kinase
NYR48_RS08730	COG0835	chemotaxis
NYR48_RS08735	COG1776	CheC inhibitor of MCP methylation
NYR48_RS08745	COG1191	sigma factor activity
NYR48_RS08775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NYR48_RS08780	COG4589	Belongs to the CDS family
NYR48_RS08790	COG0750	zinc metalloprotease
NYR48_RS08810	COG0195	Participates in both transcription termination and antitermination
NYR48_RS08815	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NYR48_RS08820	COG1358	cellular component organization or biogenesis
NYR48_RS08830	COG1550	Protein conserved in bacteria
NYR48_RS08845	COG0196	riboflavin kinase activity
NYR48_RS08860	COG0726	polysaccharide deacetylase
NYR48_RS08865	COG0612	Peptidase, M16
NYR48_RS08870	COG1873	PFAM PRC-barrel domain
NYR48_RS08875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NYR48_RS08880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NYR48_RS08885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NYR48_RS08890	COG0527	aspartate kinase activity
NYR48_RS08900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NYR48_RS08905	COG0740	serine-type endopeptidase activity
NYR48_RS08915	COG1674	ftsk spoiiie
NYR48_RS08915	COG4980	gas vesicle protein
NYR48_RS08920	COG2188	Transcriptional regulator
NYR48_RS08925	COG2814	Major facilitator Superfamily
NYR48_RS08930	COG1846	Transcriptional regulator
NYR48_RS08935	COG2409	Drug exporters of the RND superfamily
NYR48_RS08935	COG1033	growth of symbiont in host cell
NYR48_RS08940	COG0612	Peptidase, M16
NYR48_RS08945	COG0612	Peptidase, M16
NYR48_RS08950	COG0300	oxidoreductase activity
NYR48_RS08965	COG1426	Protein conserved in bacteria
NYR48_RS08970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NYR48_RS08985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NYR48_RS08995	COG1692	metallophosphoesterase
NYR48_RS09000	COG2359	stage V sporulation protein S
NYR48_RS09020	COG4550	Control of competence regulator ComK, YlbF/YmcA
NYR48_RS09065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS09070	COG3425	synthase
NYR48_RS09075	COG1024	Enoyl-CoA hydratase
NYR48_RS09080	COG1024	Enoyl-CoA hydratase
NYR48_RS09085	COG3321	synthase
NYR48_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS09085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS09085	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS09085	COG0300	oxidoreductase activity
NYR48_RS09090	COG4221	oxidoreductase activity
NYR48_RS09090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS09090	COG0300	oxidoreductase activity
NYR48_RS09090	COG3321	synthase
NYR48_RS09095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYR48_RS09095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS09095	COG3321	synthase
NYR48_RS09095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS09095	COG3321	synthase
NYR48_RS09095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYR48_RS09100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS09100	COG4221	oxidoreductase activity
NYR48_RS09100	COG3321	synthase
NYR48_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS09105	COG3321	synthase
NYR48_RS09105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS09105	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NYR48_RS09105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NYR48_RS09110	COG2124	cytochrome p450
NYR48_RS09115	COG3209	COG3209 Rhs family protein
NYR48_RS09120	COG3619	membrane
NYR48_RS09130	COG1404	Belongs to the peptidase S8 family
NYR48_RS09140	COG4195	phage-related replication protein
NYR48_RS09145	COG1764	response to oxidative stress
NYR48_RS09155	COG2076	Multidrug Resistance protein
NYR48_RS09195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NYR48_RS09200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NYR48_RS09205	COG4112	unkown
NYR48_RS09210	COG0860	N-Acetylmuramoyl-L-alanine amidase
NYR48_RS09215	COG0464	growth
NYR48_RS09220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NYR48_RS09225	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NYR48_RS09230	COG0789	Transcriptional regulator
NYR48_RS09235	COG0174	glutamine synthetase
NYR48_RS09285	COG1196	nuclear chromosome segregation
NYR48_RS09285	COG0739	heme binding
NYR48_RS09285	COG0741	lytic transglycosylase activity
NYR48_RS09300	COG2211	Major facilitator Superfamily
NYR48_RS09305	COG3507	Belongs to the glycosyl hydrolase 43 family
NYR48_RS09320	COG1070	Carbohydrate kinase
NYR48_RS09325	COG0574	Belongs to the PEP-utilizing enzyme family
NYR48_RS09325	COG3848	Pyruvate phosphate dikinase
NYR48_RS09345	COG2318	DinB family
NYR48_RS09350	COG1064	alcohol dehydrogenase
NYR48_RS09355	COG4451	ribulose bisphosphate carboxylase, small
NYR48_RS09355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NYR48_RS09390	COG5444	nuclease activity
NYR48_RS09430	COG3397	chitin binding
NYR48_RS09440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NYR48_RS09455	COG5434	Belongs to the glycosyl hydrolase 28 family
NYR48_RS09460	COG0756	dUTP diphosphatase activity
NYR48_RS09465	COG4195	phage-related replication protein
NYR48_RS09500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NYR48_RS09510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NYR48_RS09530	COG0785	Cytochrome C biogenesis protein
NYR48_RS09535	COG2201	protein-glutamate methylesterase activity
NYR48_RS09540	COG4846	Membrane protein involved in cytochrome C biogenesis
NYR48_RS09550	COG0071	Belongs to the small heat shock protein (HSP20) family
NYR48_RS09565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NYR48_RS09570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYR48_RS09590	COG0824	Thioesterase
NYR48_RS09600	COG4841	protein insertion into membrane
NYR48_RS09610	COG1832	CoA-binding protein
NYR48_RS09615	COG0187	DNA topoisomerase II activity
NYR48_RS09620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NYR48_RS09635	COG1115	amino acid carrier protein
NYR48_RS09645	COG1063	alcohol dehydrogenase
NYR48_RS09650	COG0800	Aldolase
NYR48_RS09655	COG1312	Catalyzes the dehydration of D-mannonate
NYR48_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS09665	COG1609	Transcriptional regulator
NYR48_RS09670	COG2271	Major facilitator Superfamily
NYR48_RS09695	COG1136	(ABC) transporter
NYR48_RS09695	COG0577	efflux transmembrane transporter activity
NYR48_RS09725	COG2205	protein histidine kinase activity
NYR48_RS09730	COG0745	RESPONSE REGULATOR receiver
NYR48_RS09740	COG3507	Belongs to the glycosyl hydrolase 43 family
NYR48_RS09765	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS09770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NYR48_RS09775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NYR48_RS09780	COG2610	gluconate transmembrane transporter activity
NYR48_RS09785	COG2124	cytochrome p450
NYR48_RS09805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NYR48_RS09815	COG2246	polysaccharide biosynthetic process
NYR48_RS09820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NYR48_RS09825	COG0586	Pfam SNARE associated Golgi protein
NYR48_RS09830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NYR48_RS09835	COG1024	Enoyl-CoA hydratase
NYR48_RS09840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NYR48_RS09845	COG0511	ligase activity, forming carbon-carbon bonds
NYR48_RS09850	COG0439	Biotin carboxylase
NYR48_RS09855	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS09860	COG1960	acyl-CoA dehydrogenase activity
NYR48_RS09865	COG1649	PFAM Uncharacterised BCR, COG1649
NYR48_RS09875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS09875	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NYR48_RS09880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS09885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS09890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS09895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS09900	COG2027	D-alanyl-D-alanine carboxypeptidase
NYR48_RS09905	COG2017	converts alpha-aldose to the beta-anomer
NYR48_RS09910	COG0534	Mate efflux family protein
NYR48_RS09925	COG0582	viral genome integration into host DNA
NYR48_RS09930	COG0166	Belongs to the GPI family
NYR48_RS09935	COG0405	Gamma-glutamyltransferase
NYR48_RS09940	COG2814	Major facilitator Superfamily
NYR48_RS09945	COG0640	Transcriptional regulator
NYR48_RS09950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NYR48_RS09960	COG0604	alcohol dehydrogenase
NYR48_RS09965	COG0493	'glutamate synthase
NYR48_RS09970	COG0067	glutamate synthase
NYR48_RS09970	COG0069	glutamate synthase activity
NYR48_RS09970	COG0070	glutamate synthase
NYR48_RS09975	COG0583	DNA-binding transcription factor activity
NYR48_RS09980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NYR48_RS09995	COG0300	oxidoreductase activity
NYR48_RS10000	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NYR48_RS10010	COG2814	Major facilitator Superfamily
NYR48_RS10015	COG1070	Carbohydrate kinase
NYR48_RS10020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NYR48_RS10025	COG0243	molybdopterin cofactor binding
NYR48_RS10055	COG5444	nuclease activity
NYR48_RS10060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NYR48_RS10065	COG0662	Cupin 2, conserved barrel domain protein
NYR48_RS10065	COG2207	Transcriptional regulator
NYR48_RS10070	COG1309	transcriptional regulator
NYR48_RS10075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NYR48_RS10085	COG0640	Transcriptional regulator
NYR48_RS10090	COG0741	lytic transglycosylase activity
NYR48_RS10095	COG2322	membrane
NYR48_RS10110	COG1619	proteins homologs of microcin C7 resistance protein MccF
NYR48_RS10120	COG1388	LysM domain
NYR48_RS10120	COG3584	3D domain protein
NYR48_RS10125	COG0514	ATP-dependent DNA helicase (RecQ)
NYR48_RS10135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NYR48_RS10140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NYR48_RS10155	COG0071	Belongs to the small heat shock protein (HSP20) family
NYR48_RS10185	COG1012	belongs to the aldehyde dehydrogenase family
NYR48_RS10190	COG1657	PFAM Prenyltransferase squalene oxidase
NYR48_RS10195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NYR48_RS10200	COG0733	neurotransmitter:sodium symporter activity
NYR48_RS10205	COG0385	Bile acid
NYR48_RS10210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NYR48_RS10215	COG0508	dehydrogenase complex catalyzes the overall conversion of
NYR48_RS10225	COG4548	von Willebrand factor, type A
NYR48_RS10230	COG0714	Associated with various cellular activities
NYR48_RS10235	COG2032	superoxide dismutase activity
NYR48_RS10240	COG1388	LysM domain
NYR48_RS10240	COG0791	NLP P60 protein
NYR48_RS10245	COG1819	glycosyl
NYR48_RS10250	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NYR48_RS10255	COG0534	Mate efflux family protein
NYR48_RS10260	COG1366	Belongs to the anti-sigma-factor antagonist family
NYR48_RS10265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NYR48_RS10270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NYR48_RS10280	COG2962	Rard protein
NYR48_RS10295	COG1942	4-Oxalocrotonate Tautomerase
NYR48_RS10305	COG1733	regulation of RNA biosynthetic process
NYR48_RS10310	COG0778	Nitroreductase
NYR48_RS10315	COG0400	carboxylic ester hydrolase activity
NYR48_RS10320	COG0346	lactoylglutathione lyase activity
NYR48_RS10330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NYR48_RS10340	COG2723	6-phospho-beta-galactosidase activity
NYR48_RS10345	COG2188	Transcriptional regulator
NYR48_RS10350	COG3409	Peptidoglycan-binding domain 1 protein
NYR48_RS10350	COG0793	Belongs to the peptidase S41A family
NYR48_RS10355	COG2226	methyltransferase
NYR48_RS10365	COG1876	peptidase activity
NYR48_RS10385	COG0671	phosphoesterase, PA-phosphatase related
NYR48_RS10420	COG1509	lysine 2,3-aminomutase activity
NYR48_RS10425	COG0456	acetyltransferase
NYR48_RS10430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NYR48_RS10435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NYR48_RS10440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NYR48_RS10445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NYR48_RS10460	COG0456	acetyltransferase
NYR48_RS10465	COG0463	Glycosyl transferase, family 2
NYR48_RS10480	COG4641	Protein conserved in bacteria
NYR48_RS10490	COG1086	Polysaccharide biosynthesis protein
NYR48_RS10515	COG1388	LysM domain
NYR48_RS10520	COG0457	Tetratricopeptide repeat
NYR48_RS10530	COG1012	belongs to the aldehyde dehydrogenase family
NYR48_RS10540	COG0457	Tetratricopeptide repeat
NYR48_RS10560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NYR48_RS10565	COG1114	Component of the transport system for branched-chain amino acids
NYR48_RS10575	COG1687	branched-chain amino acid
NYR48_RS10580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NYR48_RS10585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYR48_RS10635	COG1846	Transcriptional regulator
NYR48_RS10640	COG4698	Protein conserved in bacteria
NYR48_RS10645	COG2755	lipolytic protein G-D-S-L family
NYR48_RS10650	COG1999	signal sequence binding
NYR48_RS10660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NYR48_RS10665	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NYR48_RS10670	COG1272	protein, Hemolysin III
NYR48_RS10675	COG0204	Acyl-transferase
NYR48_RS10680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NYR48_RS10695	COG2136	Putative SAM-dependent methyltransferase
NYR48_RS10695	COG2521	methyltransferase
NYR48_RS10710	COG1413	lyase activity
NYR48_RS10715	COG1418	mRNA catabolic process
NYR48_RS10720	COG0386	Belongs to the glutathione peroxidase family
NYR48_RS10730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NYR48_RS10740	COG1278	Cold shock
NYR48_RS10760	COG0328	RNA-DNA hybrid ribonuclease activity
NYR48_RS10765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NYR48_RS10770	COG0328	RNA-DNA hybrid ribonuclease activity
NYR48_RS10780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NYR48_RS10795	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NYR48_RS10805	COG1755	Isoprenylcysteine carboxyl methyltransferase
NYR48_RS10810	COG3424	synthase
NYR48_RS10830	COG2323	membrane
NYR48_RS10835	COG1335	isochorismatase
NYR48_RS10845	COG2233	PERMEase
NYR48_RS10855	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NYR48_RS10860	COG1199	ATP-dependent helicase activity
NYR48_RS10875	COG0116	Belongs to the methyltransferase superfamily
NYR48_RS10905	COG3359	exonuclease
NYR48_RS10910	COG1111	helicase
NYR48_RS10910	COG1205	dead DEAH box helicase
NYR48_RS10915	COG2190	(PTS) system
NYR48_RS10920	COG0071	Belongs to the small heat shock protein (HSP20) family
NYR48_RS10960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NYR48_RS10960	COG4499	WXG100 protein secretion system (Wss), protein YukC
NYR48_RS10970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NYR48_RS10975	COG3935	DnaD domain protein
NYR48_RS10985	COG0436	Aminotransferase
NYR48_RS10990	COG5353	protein conserved in bacteria
NYR48_RS11000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NYR48_RS11000	COG1199	ATP-dependent helicase activity
NYR48_RS11030	COG0438	transferase activity, transferring glycosyl groups
NYR48_RS11035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NYR48_RS11050	COG1694	Mazg nucleotide pyrophosphohydrolase
NYR48_RS11055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NYR48_RS11060	COG2140	Oxalate decarboxylase
NYR48_RS11070	COG4347	Protein of unknown function (DUF1405)
NYR48_RS11075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NYR48_RS11075	COG2010	Cytochrome c
NYR48_RS11080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NYR48_RS11085	COG0723	plastoquinol--plastocyanin reductase activity
NYR48_RS11100	COG0457	Tetratricopeptide repeat
NYR48_RS11110	COG0287	Prephenate dehydrogenase
NYR48_RS11145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NYR48_RS11150	COG4401	Chorismate mutase type I
NYR48_RS11165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NYR48_RS11170	COG0105	UTP biosynthetic process
NYR48_RS11175	COG0142	geranyltranstransferase activity
NYR48_RS11185	COG0142	geranyltranstransferase activity
NYR48_RS11200	COG0776	regulation of translation
NYR48_RS11205	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NYR48_RS11245	COG0539	negative regulation of cytoplasmic translation
NYR48_RS11260	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NYR48_RS11265	COG2959	enzyme of heme biosynthesis
NYR48_RS11270	COG3409	Peptidoglycan-binding domain 1 protein
NYR48_RS11270	COG3773	Cell wall hydrolase
NYR48_RS11275	COG2339	peptidase activity
NYR48_RS11280	COG0492	ferredoxin-NADP+ reductase activity
NYR48_RS11285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NYR48_RS11290	COG4862	establishment of competence for transformation
NYR48_RS11295	COG1408	metallophosphoesterase
NYR48_RS11305	COG1388	LysM domain
NYR48_RS11310	COG1266	CAAX protease self-immunity
NYR48_RS11315	COG0514	ATP-dependent DNA helicase (RecQ)
NYR48_RS11320	COG4955	Helix-turn-helix domain
NYR48_RS11325	COG1141	Ferredoxin
NYR48_RS11330	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NYR48_RS11335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NYR48_RS11345	COG1595	DNA-templated transcription, initiation
NYR48_RS11350	COG5002	protein histidine kinase activity
NYR48_RS11355	COG0745	RESPONSE REGULATOR receiver
NYR48_RS11360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NYR48_RS11365	COG1333	cytochrome c biogenesis protein
NYR48_RS11370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYR48_RS11375	COG1187	pseudouridine synthase activity
NYR48_RS11380	COG0700	Nucleoside recognition
NYR48_RS11385	COG2715	membrane protein required for spore maturation
NYR48_RS11390	COG1686	Belongs to the peptidase S11 family
NYR48_RS11415	COG1547	Domain of unknown function (DUF309)
NYR48_RS11420	COG0456	acetyltransferase
NYR48_RS11435	COG0307	riboflavin synthase, alpha
NYR48_RS11440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NYR48_RS11440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NYR48_RS11450	COG0681	Belongs to the peptidase S26 family
NYR48_RS11460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NYR48_RS11465	COG4086	secreted protein
NYR48_RS11470	COG0019	diaminopimelate decarboxylase activity
NYR48_RS11475	COG0697	spore germination
NYR48_RS11490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYR48_RS11510	COG1191	sigma factor activity
NYR48_RS11520	COG1366	Belongs to the anti-sigma-factor antagonist family
NYR48_RS11525	COG1686	Belongs to the peptidase S11 family
NYR48_RS11530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NYR48_RS11535	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NYR48_RS11540	COG4974	Belongs to the 'phage' integrase family
NYR48_RS11550	COG0735	belongs to the Fur family
NYR48_RS11555	COG1300	Membrane
NYR48_RS11570	COG0281	malic enzyme
NYR48_RS11575	COG1757	Na H antiporter
NYR48_RS11580	COG1027	Aspartate ammonia-lyase
NYR48_RS11585	COG0252	asparaginase activity
NYR48_RS11590	COG1396	sequence-specific DNA binding
NYR48_RS11595	COG1379	DNA repair
NYR48_RS11600	COG0494	nUDIX hydrolase
NYR48_RS11610	COG0667	Aldo Keto reductase
NYR48_RS11620	COG1073	alpha beta
NYR48_RS11630	COG4918	Iron-sulphur cluster biosynthesis
NYR48_RS11635	COG0456	acetyltransferase
NYR48_RS11635	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NYR48_RS11640	COG2329	Antibiotic biosynthesis monooxygenase
NYR48_RS11645	COG0456	acetyltransferase
NYR48_RS11650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NYR48_RS11665	COG0628	permease
NYR48_RS11675	COG0346	lactoylglutathione lyase activity
NYR48_RS11685	COG3048	D-serine ammonia-lyase activity
NYR48_RS11690	COG0300	oxidoreductase activity
NYR48_RS11695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NYR48_RS11700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NYR48_RS11705	COG1024	Enoyl-CoA hydratase
NYR48_RS11710	COG3425	synthase
NYR48_RS11715	COG2124	cytochrome p450
NYR48_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS11720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS11720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYR48_RS11720	COG3321	synthase
NYR48_RS11720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS11725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS11725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYR48_RS11725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS11725	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS11725	COG3321	synthase
NYR48_RS11730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS11730	COG0300	oxidoreductase activity
NYR48_RS11730	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS11730	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS11730	COG3321	synthase
NYR48_RS11735	COG3321	synthase
NYR48_RS11735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS11735	COG0300	oxidoreductase activity
NYR48_RS11735	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS11740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS11740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS11740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYR48_RS11740	COG3321	synthase
NYR48_RS11740	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS11745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS11745	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS11745	COG0300	oxidoreductase activity
NYR48_RS11745	COG3321	synthase
NYR48_RS11745	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS11750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYR48_RS11750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYR48_RS11750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS11750	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS11750	COG3321	synthase
NYR48_RS11755	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS11760	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS11775	COG2070	2-Nitropropane dioxygenase
NYR48_RS11775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NYR48_RS11780	COG0250	Participates in transcription elongation, termination and antitermination
NYR48_RS11800	COG0596	Alpha beta hydrolase
NYR48_RS11815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NYR48_RS11820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NYR48_RS11835	COG0706	membrane insertase activity
NYR48_RS11840	COG2195	Cleaves the N-terminal amino acid of tripeptides
NYR48_RS11845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NYR48_RS11850	COG0346	lactoylglutathione lyase activity
NYR48_RS11860	COG1376	ErfK ybiS ycfS ynhG family protein
NYR48_RS11865	COG4129	membrane
NYR48_RS11870	COG1126	abc transporter atp-binding protein
NYR48_RS11875	COG0765	amino acid transport
NYR48_RS11880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NYR48_RS11890	COG1597	lipid kinase activity
NYR48_RS11895	COG0508	dehydrogenase complex catalyzes the overall conversion of
NYR48_RS11900	COG0022	dehydrogenase e1 component
NYR48_RS11905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NYR48_RS11910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NYR48_RS11915	COG3426	butyrate kinase activity
NYR48_RS11920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NYR48_RS11925	COG0280	phosphate acetyltransferase
NYR48_RS11930	COG3290	protein histidine kinase activity
NYR48_RS11930	COG3829	transcription factor binding
NYR48_RS11940	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NYR48_RS11945	COG2079	MmgE PrpD family protein
NYR48_RS11950	COG0372	Belongs to the citrate synthase family
NYR48_RS11955	COG1960	acyl-CoA dehydrogenase activity
NYR48_RS11960	COG1250	3-hydroxyacyl-CoA dehydrogenase
NYR48_RS11965	COG0183	Belongs to the thiolase family
NYR48_RS11970	COG0584	glycerophosphoryl diester phosphodiesterase
NYR48_RS11975	COG0860	N-Acetylmuramoyl-L-alanine amidase
NYR48_RS12000	COG1902	pentaerythritol trinitrate reductase activity
NYR48_RS12015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NYR48_RS12020	COG0745	RESPONSE REGULATOR receiver
NYR48_RS12025	COG0750	zinc metalloprotease
NYR48_RS12030	COG0497	DNA recombination
NYR48_RS12040	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NYR48_RS12050	COG0142	geranyltranstransferase activity
NYR48_RS12060	COG1570	exodeoxyribonuclease VII activity
NYR48_RS12075	COG1302	Protein conserved in bacteria
NYR48_RS12080	COG0439	Biotin carboxylase
NYR48_RS12085	COG0511	ligase activity, forming carbon-carbon bonds
NYR48_RS12125	COG3854	ATPases associated with a variety of cellular activities
NYR48_RS12140	COG0006	proline dipeptidase activity
NYR48_RS12150	COG3872	metal-dependent enzyme
NYR48_RS12160	COG1752	Esterase of the alpha-beta hydrolase superfamily
NYR48_RS12175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NYR48_RS12195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NYR48_RS12210	COG1396	sequence-specific DNA binding
NYR48_RS12220	COG0681	Belongs to the peptidase S26 family
NYR48_RS12245	COG4940	Competence protein ComGF
NYR48_RS12255	COG4970	Tfp pilus assembly protein FimT
NYR48_RS12260	COG4537	Required for transformation and DNA binding
NYR48_RS12265	COG1459	type II secretion system
NYR48_RS12270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NYR48_RS12275	COG0598	Magnesium transport protein CorA
NYR48_RS12280	COG1253	flavin adenine dinucleotide binding
NYR48_RS12285	COG1366	Belongs to the anti-sigma-factor antagonist family
NYR48_RS12295	COG1393	Belongs to the ArsC family
NYR48_RS12305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NYR48_RS12315	COG0011	TIGRFAM Protein of
NYR48_RS12325	COG2866	Carboxypeptidase
NYR48_RS12330	COG1940	carbohydrate kinase activity
NYR48_RS12335	COG4483	Protein conserved in bacteria
NYR48_RS12340	COG1757	Na H antiporter
NYR48_RS12350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NYR48_RS12365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NYR48_RS12370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NYR48_RS12375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NYR48_RS12380	COG0581	inorganic phosphate transmembrane transporter activity
NYR48_RS12385	COG0573	inorganic phosphate transmembrane transporter activity
NYR48_RS12390	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NYR48_RS12395	COG0768	penicillin binding
NYR48_RS12400	COG0477	Major facilitator Superfamily
NYR48_RS12405	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NYR48_RS12410	COG2839	Protein conserved in bacteria
NYR48_RS12415	COG5521	maltodextrose utilization protein MalA
NYR48_RS12420	COG1388	LysM domain
NYR48_RS12430	COG4709	membrane
NYR48_RS12435	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NYR48_RS12440	COG0735	belongs to the Fur family
NYR48_RS12445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NYR48_RS12460	COG0513	Belongs to the DEAD box helicase family
NYR48_RS12475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NYR48_RS12480	COG2384	SAM-dependent methyltransferase
NYR48_RS12485	COG2010	Cytochrome c
NYR48_RS12490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NYR48_RS12495	COG0358	DNA primase activity
NYR48_RS12510	COG0517	IMP dehydrogenase activity
NYR48_RS12515	COG0751	glycine-tRNA ligase activity
NYR48_RS12535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NYR48_RS12540	COG0295	cytidine deaminase activity
NYR48_RS12545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NYR48_RS12555	COG1480	7TM receptor with intracellular HD hydrolase
NYR48_RS12560	COG1702	phosphate starvation-inducible protein PhoH
NYR48_RS12565	COG0561	phosphatase activity
NYR48_RS12580	COG4864	UPF0365 protein
NYR48_RS12585	COG1030	water channel activity
NYR48_RS12590	COG1610	YqeY-like protein
NYR48_RS12600	COG1283	sodium-dependent phosphate transmembrane transporter activity
NYR48_RS12605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NYR48_RS12610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NYR48_RS12640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NYR48_RS12655	COG0860	N-Acetylmuramoyl-L-alanine amidase
NYR48_RS12685	COG0658	competence protein
NYR48_RS12685	COG2333	competence protein COMEC
NYR48_RS12690	COG2131	deaminase
NYR48_RS12695	COG1555	photosystem II stabilization
NYR48_RS12695	COG1596	polysaccharide export
NYR48_RS12700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NYR48_RS12705	COG2226	methyltransferase
NYR48_RS12710	COG0799	negative regulation of ribosome biogenesis
NYR48_RS12715	COG1713	HD superfamily hydrolase involved in NAD metabolism
NYR48_RS12725	COG1534	Rna-binding protein
NYR48_RS12730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NYR48_RS12735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NYR48_RS12740	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NYR48_RS12755	COG2755	lipolytic protein G-D-S-L family
NYR48_RS12765	COG0398	Pfam SNARE associated Golgi protein
NYR48_RS12805	COG0563	adenylate kinase activity
NYR48_RS12815	COG2814	Major facilitator Superfamily
NYR48_RS12820	COG0456	acetyltransferase
NYR48_RS12825	COG2318	DinB family
NYR48_RS12835	COG0561	phosphatase activity
NYR48_RS12840	COG0561	phosphatase activity
NYR48_RS12850	COG1482	cell wall glycoprotein biosynthetic process
NYR48_RS12855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NYR48_RS12855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NYR48_RS12855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NYR48_RS12860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NYR48_RS12860	COG3711	transcriptional antiterminator
NYR48_RS12870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NYR48_RS12875	COG0583	DNA-binding transcription factor activity
NYR48_RS12880	COG2814	Major facilitator Superfamily
NYR48_RS12885	COG2124	cytochrome p450
NYR48_RS12885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NYR48_RS12890	COG1309	transcriptional regulator
NYR48_RS12895	COG2226	methyltransferase
NYR48_RS12910	COG2116	formate transmembrane transporter activity
NYR48_RS12915	COG5609	conserved protein (DUF2294)
NYR48_RS12920	COG3383	formate dehydrogenase (NAD+) activity
NYR48_RS12925	COG2427	Protein of unknown function (DUF1641)
NYR48_RS12935	COG0626	cystathionine gamma-synthase activity
NYR48_RS12940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NYR48_RS12965	COG0768	penicillin binding
NYR48_RS12980	COG0826	peptidase U32
NYR48_RS12985	COG0826	peptidase U32
NYR48_RS12990	COG4122	O-methyltransferase activity
NYR48_RS12995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NYR48_RS13010	COG4472	Bacterial protein of unknown function (DUF965)
NYR48_RS13020	COG0628	permease
NYR48_RS13025	COG1126	abc transporter atp-binding protein
NYR48_RS13030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NYR48_RS13035	COG0765	amino acid transport
NYR48_RS13040	COG0765	amino acid transport
NYR48_RS13055	COG3881	PFAM PRC-barrel domain
NYR48_RS13060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NYR48_RS13065	COG0457	Tetratricopeptide repeat
NYR48_RS13075	COG1104	cysteine desulfurase activity
NYR48_RS13080	COG1959	2 iron, 2 sulfur cluster binding
NYR48_RS13085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NYR48_RS13090	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NYR48_RS13115	COG4991	sh3 domain protein
NYR48_RS13115	COG0860	N-Acetylmuramoyl-L-alanine amidase
NYR48_RS13115	COG3103	Sh3 type 3 domain protein
NYR48_RS13125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NYR48_RS13135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NYR48_RS13135	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NYR48_RS13140	COG5416	Lipopolysaccharide assembly protein A domain
NYR48_RS13145	COG0490	domain, Protein
NYR48_RS13150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NYR48_RS13150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NYR48_RS13160	COG2244	polysaccharide biosynthetic process
NYR48_RS13165	COG2323	membrane
NYR48_RS13175	COG1862	Preprotein translocase
NYR48_RS13215	COG1388	LysM domain
NYR48_RS13225	COG0157	Belongs to the NadC ModD family
NYR48_RS13230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NYR48_RS13235	COG1104	cysteine desulfurase activity
NYR48_RS13240	COG1827	regulation of RNA biosynthetic process
NYR48_RS13245	COG0077	Prephenate dehydratase
NYR48_RS13260	COG3290	protein histidine kinase activity
NYR48_RS13265	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NYR48_RS13270	COG2868	ribosomal protein
NYR48_RS13280	COG1994	Peptidase M50
NYR48_RS13285	COG0739	heme binding
NYR48_RS13290	COG2894	cell division
NYR48_RS13300	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NYR48_RS13310	COG1077	Cell shape determining protein MreB Mrl
NYR48_RS13330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NYR48_RS13335	COG0285	dihydrofolate synthase activity
NYR48_RS13340	COG0525	valine-tRNA ligase activity
NYR48_RS13350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NYR48_RS13355	COG1388	LysM domain
NYR48_RS13365	COG0113	porphobilinogen synthase activity
NYR48_RS13370	COG1587	Uroporphyrinogen-III synthase
NYR48_RS13380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NYR48_RS13400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NYR48_RS13405	COG1067	ATP-dependent peptidase activity
NYR48_RS13405	COG0470	DNA polymerase III
NYR48_RS13420	COG0457	Tetratricopeptide repeat
NYR48_RS13420	COG1477	protein flavinylation
NYR48_RS13435	COG0473	3-isopropylmalate dehydrogenase activity
NYR48_RS13450	COG0440	acetolactate synthase activity
NYR48_RS13455	COG0028	Belongs to the TPP enzyme family
NYR48_RS13480	COG0622	Phosphoesterase
NYR48_RS13485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NYR48_RS13495	COG5401	PFAM Sporulation and spore germination
NYR48_RS13505	COG1846	Transcriptional regulator
NYR48_RS13510	COG2197	response regulator
NYR48_RS13515	COG0824	Thioesterase
NYR48_RS13520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NYR48_RS13525	COG1053	succinate dehydrogenase
NYR48_RS13530	COG2009	succinate dehydrogenase
NYR48_RS13535	COG1719	4-vinyl reductase, 4VR
NYR48_RS13540	COG0527	aspartate kinase activity
NYR48_RS13550	COG3118	belongs to the thioredoxin family
NYR48_RS13555	COG3534	alpha-L-arabinofuranosidase
NYR48_RS13560	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NYR48_RS13565	COG2086	electron transfer activity
NYR48_RS13570	COG1024	Enoyl-CoA hydratase
NYR48_RS13575	COG1309	transcriptional regulator
NYR48_RS13580	COG0318	PFAM AMP-dependent synthetase and ligase
NYR48_RS13590	COG3766	membrane
NYR48_RS13600	COG1796	DNA polymerase
NYR48_RS13600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NYR48_RS13605	COG1286	toxin biosynthetic process
NYR48_RS13620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NYR48_RS13620	COG0072	phenylalanine-tRNA ligase activity
NYR48_RS13625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NYR48_RS13630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NYR48_RS13640	COG3835	regulator
NYR48_RS13645	COG0277	FAD linked oxidase domain protein
NYR48_RS13650	COG0247	lactate metabolic process
NYR48_RS13655	COG1966	Carbon starvation protein
NYR48_RS13660	COG3534	alpha-L-arabinofuranosidase
NYR48_RS13665	COG0395	ABC-type sugar transport system, permease component
NYR48_RS13670	COG1175	transmembrane transport
NYR48_RS13675	COG1653	transport
NYR48_RS13685	COG0647	UMP catabolic process
NYR48_RS13690	COG0235	Class ii aldolase
NYR48_RS13695	COG1069	ribulokinase activity
NYR48_RS13700	COG2160	L-arabinose isomerase activity
NYR48_RS13705	COG3507	Belongs to the glycosyl hydrolase 43 family
NYR48_RS13710	COG1363	Peptidase, m42
NYR48_RS13720	COG3326	Membrane
NYR48_RS13725	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NYR48_RS13735	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NYR48_RS13740	COG1346	cytolysis
NYR48_RS13745	COG1380	Effector of murein hydrolase LrgA
NYR48_RS13750	COG3279	Response regulator of the LytR AlgR family
NYR48_RS13755	COG3275	phosphorelay sensor kinase activity
NYR48_RS13760	COG1011	Hydrolase
NYR48_RS13775	COG0398	Pfam SNARE associated Golgi protein
NYR48_RS13780	COG1484	DNA-dependent DNA replication
NYR48_RS13785	COG3611	Membrane attachment protein
NYR48_RS13800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NYR48_RS13805	COG1733	regulation of RNA biosynthetic process
NYR48_RS13810	COG2814	Major facilitator Superfamily
NYR48_RS13815	COG0656	L-ascorbic acid biosynthetic process
NYR48_RS13820	COG0237	dephospho-CoA kinase activity
NYR48_RS13825	COG1971	Probably functions as a manganese efflux pump
NYR48_RS13830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NYR48_RS13835	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NYR48_RS13835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NYR48_RS13840	COG5002	protein histidine kinase activity
NYR48_RS13845	COG0745	RESPONSE REGULATOR receiver
NYR48_RS13855	COG0538	isocitrate dehydrogenase activity
NYR48_RS13860	COG0372	Belongs to the citrate synthase family
NYR48_RS13885	COG0628	permease
NYR48_RS13890	COG3030	protein affecting phage T7 exclusion by the F plasmid
NYR48_RS13895	COG0469	pyruvate kinase activity
NYR48_RS13915	COG0281	malic enzyme
NYR48_RS13920	COG0587	DNA-directed DNA polymerase activity
NYR48_RS13940	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NYR48_RS13950	COG4109	DRTGG domain
NYR48_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS13980	COG0521	Mo-molybdopterin cofactor biosynthetic process
NYR48_RS13990	COG0827	DNA restriction-modification system
NYR48_RS13995	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NYR48_RS14000	COG3874	Sporulation protein YtfJ
NYR48_RS14010	COG1714	RDD family
NYR48_RS14015	COG0616	signal peptide processing
NYR48_RS14020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NYR48_RS14025	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NYR48_RS14030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NYR48_RS14045	COG1104	cysteine desulfurase activity
NYR48_RS14050	COG1114	Component of the transport system for branched-chain amino acids
NYR48_RS14060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NYR48_RS14065	COG1309	transcriptional regulator
NYR48_RS14070	COG1956	GAF domain-containing protein
NYR48_RS14075	COG2199	diguanylate cyclase activity
NYR48_RS14075	COG2203	Gaf domain
NYR48_RS14085	COG1012	belongs to the aldehyde dehydrogenase family
NYR48_RS14110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NYR48_RS14110	COG1017	nitric oxide dioxygenase activity
NYR48_RS14120	COG0693	protein deglycase activity
NYR48_RS14140	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NYR48_RS14145	COG1378	Sugar-specific transcriptional regulator TrmB
NYR48_RS14170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NYR48_RS14175	COG0454	-acetyltransferase
NYR48_RS14180	COG0517	IMP dehydrogenase activity
NYR48_RS14185	COG0123	including yeast histone deacetylase and acetoin utilization protein
NYR48_RS14190	COG1360	Flagellar Motor Protein
NYR48_RS14195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NYR48_RS14200	COG1609	Transcriptional regulator
NYR48_RS14205	COG1605	Chorismate mutase
NYR48_RS14205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NYR48_RS14210	COG3118	belongs to the thioredoxin family
NYR48_RS14215	COG4980	gas vesicle protein
NYR48_RS14220	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NYR48_RS14230	COG1674	ftsk spoiiie
NYR48_RS14235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NYR48_RS14245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYR48_RS14255	COG1363	Peptidase, m42
NYR48_RS14260	COG5584	Small secreted protein
NYR48_RS14265	COG0281	malic enzyme
NYR48_RS14270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NYR48_RS14285	COG0510	thiamine kinase activity
NYR48_RS14290	COG1597	lipid kinase activity
NYR48_RS14300	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NYR48_RS14305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NYR48_RS14310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NYR48_RS14315	COG2252	PERMEase
NYR48_RS14320	COG4473	ABC transporter
NYR48_RS14325	COG1131	(ABC) transporter
NYR48_RS14330	COG1349	DNA-binding transcription factor activity
NYR48_RS14335	COG1187	pseudouridine synthase activity
NYR48_RS14340	COG2244	polysaccharide biosynthetic process
NYR48_RS14345	COG2081	HI0933 family
NYR48_RS14350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NYR48_RS14360	COG1609	Transcriptional regulator
NYR48_RS14365	COG1653	transport
NYR48_RS14370	COG1175	transmembrane transport
NYR48_RS14375	COG0395	ABC-type sugar transport system, permease component
NYR48_RS14380	COG1486	melibiose metabolic process
NYR48_RS14390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NYR48_RS14405	COG1366	Belongs to the anti-sigma-factor antagonist family
NYR48_RS14405	COG2202	Pas domain
NYR48_RS14415	COG2814	Major facilitator Superfamily
NYR48_RS14420	COG5522	Integral membrane protein (intg_mem_TP0381)
NYR48_RS14425	COG0577	efflux transmembrane transporter activity
NYR48_RS14430	COG1136	(ABC) transporter
NYR48_RS14435	COG2205	protein histidine kinase activity
NYR48_RS14440	COG0745	RESPONSE REGULATOR receiver
NYR48_RS14445	COG0577	efflux transmembrane transporter activity
NYR48_RS14450	COG1136	(ABC) transporter
NYR48_RS14470	COG1131	(ABC) transporter
NYR48_RS14475	COG1725	Transcriptional regulator
NYR48_RS14495	COG0640	Transcriptional regulator
NYR48_RS14520	COG0477	Major facilitator Superfamily
NYR48_RS14525	COG1242	4 iron, 4 sulfur cluster binding
NYR48_RS14530	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NYR48_RS14540	COG0584	glycerophosphoryl diester phosphodiesterase
NYR48_RS14550	COG2267	carboxylic ester hydrolase activity
NYR48_RS14555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NYR48_RS14560	COG1113	amino acid transport
NYR48_RS14565	COG0367	asparagine synthase
NYR48_RS14585	COG1506	peptidase
NYR48_RS14590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NYR48_RS14595	COG1116	anion transmembrane transporter activity
NYR48_RS14600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NYR48_RS14605	COG0494	nUDIX hydrolase
NYR48_RS14610	COG4824	toxin secretion phage lysis holin
NYR48_RS14615	COG0783	Belongs to the Dps family
NYR48_RS14640	COG0288	reversible hydration of carbon dioxide
NYR48_RS14650	COG1271	oxidase subunit
NYR48_RS14655	COG1294	oxidase, subunit
NYR48_RS14665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NYR48_RS14670	COG4948	Mandelate Racemase Muconate Lactonizing
NYR48_RS14680	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NYR48_RS14685	COG0596	Alpha beta hydrolase
NYR48_RS14695	COG1169	isochorismate synthase
NYR48_RS14700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NYR48_RS14705	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NYR48_RS14830	COG3859	Proton-coupled thiamine transporter YuaJ
NYR48_RS14835	COG2268	Band 7 protein
NYR48_RS14840	COG1585	Membrane protein implicated in regulation of membrane protease activity
NYR48_RS14845	COG2318	DinB family
NYR48_RS14855	COG1454	alcohol dehydrogenase
NYR48_RS14860	COG1012	belongs to the aldehyde dehydrogenase family
NYR48_RS14865	COG1510	regulation of RNA biosynthetic process
NYR48_RS14875	COG0569	domain protein
NYR48_RS14880	COG1705	Flagellar rod assembly protein muramidase FlgJ
NYR48_RS14885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NYR48_RS14885	COG1017	nitric oxide dioxygenase activity
NYR48_RS14910	COG0628	permease
NYR48_RS14915	COG0673	inositol 2-dehydrogenase activity
NYR48_RS14920	COG0693	protein deglycase activity
NYR48_RS14925	COG0840	transmembrane signaling receptor activity
NYR48_RS14930	COG0840	transmembrane signaling receptor activity
NYR48_RS14935	COG0840	transmembrane signaling receptor activity
NYR48_RS14940	COG0840	transmembrane signaling receptor activity
NYR48_RS14955	COG2070	2-Nitropropane dioxygenase
NYR48_RS14960	COG0432	Pfam Uncharacterised protein family UPF0047
NYR48_RS14965	COG0366	Alpha amylase catalytic
NYR48_RS14970	COG1253	flavin adenine dinucleotide binding
NYR48_RS14975	COG2738	Putative neutral zinc metallopeptidase
NYR48_RS14990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NYR48_RS15015	COG1335	isochorismatase
NYR48_RS15020	COG1979	alcohol dehydrogenase
NYR48_RS15025	COG1979	alcohol dehydrogenase
NYR48_RS15030	COG2155	Conserved Protein
NYR48_RS15035	COG1098	S1 RNA binding domain
NYR48_RS15040	COG0436	Aminotransferase
NYR48_RS15045	COG1522	sequence-specific DNA binding
NYR48_RS15050	COG2267	carboxylic ester hydrolase activity
NYR48_RS15060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NYR48_RS15065	COG2205	protein histidine kinase activity
NYR48_RS15075	COG5018	Exonuclease
NYR48_RS15080	COG2814	Major facilitator Superfamily
NYR48_RS15085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NYR48_RS15090	COG3011	Protein conserved in bacteria
NYR48_RS15100	COG3290	protein histidine kinase activity
NYR48_RS15105	COG4565	transcriptional regulatory protein
NYR48_RS15110	COG1744	ABC transporter substrate-binding protein PnrA-like
NYR48_RS15115	COG3845	ABC transporter
NYR48_RS15120	COG4603	Belongs to the binding-protein-dependent transport system permease family
NYR48_RS15125	COG1079	Belongs to the binding-protein-dependent transport system permease family
NYR48_RS15135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NYR48_RS15135	COG2111	Na H antiporter
NYR48_RS15140	COG2111	Na H antiporter
NYR48_RS15145	COG1006	Multisubunit Na H antiporter MnhC subunit
NYR48_RS15150	COG0651	ATP synthesis coupled electron transport
NYR48_RS15155	COG1863	multisubunit Na H antiporter MnhE subunit
NYR48_RS15160	COG2212	antiporter activity
NYR48_RS15165	COG1320	monovalent cation:proton antiporter activity
NYR48_RS15170	COG2050	protein possibly involved in aromatic compounds catabolism
NYR48_RS15175	COG2197	response regulator
NYR48_RS15180	COG4585	Histidine kinase
NYR48_RS15190	COG0142	geranyltranstransferase activity
NYR48_RS15205	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NYR48_RS15210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NYR48_RS15215	COG1335	isochorismatase
NYR48_RS15220	COG5506	Protein of unknown function (DUF1694)
NYR48_RS15235	COG0628	permease
NYR48_RS15245	COG1418	mRNA catabolic process
NYR48_RS15250	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS15260	COG1511	domain protein
NYR48_RS15265	COG1674	ftsk spoiiie
NYR48_RS15265	COG0433	COG0433 Predicted ATPase
NYR48_RS15270	COG4499	WXG100 protein secretion system (Wss), protein YukC
NYR48_RS15275	COG5417	Belongs to the EsaB family
NYR48_RS15280	COG4842	Belongs to the WXG100 family
NYR48_RS15285	COG2508	Transcriptional regulator
NYR48_RS15285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NYR48_RS15290	COG0686	Belongs to the AlaDH PNT family
NYR48_RS15295	COG5634	Uncharacterized conserved protein (DUF2278)
NYR48_RS15300	COG3251	PFAM MbtH domain protein
NYR48_RS15305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYR48_RS15310	COG1535	isochorismatase
NYR48_RS15310	COG3433	isochorismatase activity
NYR48_RS15315	COG1021	2,3-dihydroxybenzoate-AMP ligase
NYR48_RS15320	COG1169	isochorismate synthase
NYR48_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS15330	COG2819	hydrolase of the alpha beta superfamily
NYR48_RS15335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NYR48_RS15340	COG1268	BioY protein
NYR48_RS15345	COG2056	Na+-H+ antiporter family
NYR48_RS15355	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NYR48_RS15360	COG3584	3D domain protein
NYR48_RS15375	COG1252	NADH dehydrogenase
NYR48_RS15405	COG1131	(ABC) transporter
NYR48_RS15425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NYR48_RS15430	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NYR48_RS15535	COG4974	Belongs to the 'phage' integrase family
NYR48_RS15545	COG4974	Belongs to the 'phage' integrase family
NYR48_RS15550	COG0316	Belongs to the HesB IscA family
NYR48_RS15560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NYR48_RS15570	COG1252	NADH dehydrogenase
NYR48_RS15575	COG4837	Protein of unknown function (DUF1462)
NYR48_RS15580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NYR48_RS15585	COG0823	Involved in the tonB-independent uptake of proteins
NYR48_RS15585	COG1506	peptidase
NYR48_RS15585	COG4946	Tricorn protease homolog
NYR48_RS15595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NYR48_RS15600	COG0460	homoserine dehydrogenase
NYR48_RS15605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NYR48_RS15610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NYR48_RS15615	COG0647	UMP catabolic process
NYR48_RS15620	COG2445	Protein of unknown function DUF86
NYR48_RS15625	COG4470	Protein conserved in bacteria
NYR48_RS15635	COG0739	heme binding
NYR48_RS15645	COG0737	Belongs to the 5'-nucleotidase family
NYR48_RS15650	COG0730	response to heat
NYR48_RS15655	COG1801	Protein of unknown function DUF72
NYR48_RS15670	COG2508	Transcriptional regulator
NYR48_RS15675	COG0457	Tetratricopeptide repeat
NYR48_RS15690	COG2814	Major facilitator Superfamily
NYR48_RS15695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NYR48_RS15700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NYR48_RS15705	COG2356	endonuclease I
NYR48_RS15710	COG3842	ATPase activity
NYR48_RS15715	COG2188	Transcriptional regulator
NYR48_RS15720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NYR48_RS15725	COG0395	ABC-type sugar transport system, permease component
NYR48_RS15730	COG1175	transmembrane transport
NYR48_RS15735	COG1653	transport
NYR48_RS15740	COG2222	sugar isomerase
NYR48_RS15750	COG0322	excinuclease ABC activity
NYR48_RS15755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NYR48_RS15760	COG2226	methyltransferase
NYR48_RS15770	COG3409	Peptidoglycan-binding domain 1 protein
NYR48_RS15775	COG0719	Fe-S assembly protein
NYR48_RS15780	COG0822	iron-sulfur transferase activity
NYR48_RS15785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NYR48_RS15790	COG0719	Fe-S assembly protein
NYR48_RS15795	COG0396	ATPase activity
NYR48_RS15805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NYR48_RS15810	COG1464	Belongs to the NlpA lipoprotein family
NYR48_RS15815	COG2011	ABC-type metal ion transport system permease component
NYR48_RS15820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NYR48_RS15830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYR48_RS15835	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NYR48_RS15850	COG1393	Belongs to the ArsC family
NYR48_RS15855	COG1960	acyl-CoA dehydrogenase activity
NYR48_RS15860	COG0183	Belongs to the thiolase family
NYR48_RS15865	COG1024	Enoyl-CoA hydratase
NYR48_RS15865	COG1250	3-hydroxyacyl-CoA dehydrogenase
NYR48_RS15885	COG5577	PFAM Coat F domain
NYR48_RS15890	COG1846	Transcriptional regulator
NYR48_RS15895	COG0477	Major facilitator Superfamily
NYR48_RS15900	COG0583	DNA-binding transcription factor activity
NYR48_RS15920	COG1120	ATPase activity
NYR48_RS15935	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS15940	COG0783	Belongs to the Dps family
NYR48_RS15945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NYR48_RS15950	COG0745	RESPONSE REGULATOR receiver
NYR48_RS15955	COG2205	protein histidine kinase activity
NYR48_RS15955	COG2770	Histidine kinase
NYR48_RS15965	COG1309	transcriptional regulator
NYR48_RS15970	COG0114	fumarate hydratase activity
NYR48_RS15980	COG0697	spore germination
NYR48_RS15985	COG0814	amino acid
NYR48_RS15995	COG2197	response regulator
NYR48_RS16000	COG4585	Histidine kinase
NYR48_RS16005	COG4758	membrane
NYR48_RS16010	COG3595	metallopeptidase activity
NYR48_RS16015	COG1842	Phage shock protein A
NYR48_RS16020	COG4758	membrane
NYR48_RS16025	COG2814	Major facilitator Superfamily
NYR48_RS16030	COG2096	Adenosyltransferase
NYR48_RS16035	COG1120	ATPase activity
NYR48_RS16040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYR48_RS16045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NYR48_RS16050	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS16055	COG3386	PFAM SMP-30 Gluconolaconase
NYR48_RS16060	COG2205	protein histidine kinase activity
NYR48_RS16065	COG0745	RESPONSE REGULATOR receiver
NYR48_RS16075	COG1191	sigma factor activity
NYR48_RS16085	COG2140	Oxalate decarboxylase
NYR48_RS16095	COG1120	ATPase activity
NYR48_RS16100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYR48_RS16105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYR48_RS16110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NYR48_RS16115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NYR48_RS16120	COG0531	amino acid
NYR48_RS16130	COG1988	membrane-bound metal-dependent
NYR48_RS16135	COG1368	sulfuric ester hydrolase activity
NYR48_RS16140	COG1910	domain protein
NYR48_RS16145	COG0725	ABC transporter, periplasmic molybdate-binding protein
NYR48_RS16150	COG4149	molybdate abc transporter
NYR48_RS16155	COG2197	response regulator
NYR48_RS16160	COG3850	Histidine kinase
NYR48_RS16165	COG1131	(ABC) transporter
NYR48_RS16175	COG0842	Transport permease protein
NYR48_RS16180	COG0656	L-ascorbic acid biosynthetic process
NYR48_RS16200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NYR48_RS16205	COG3973	AAA domain
NYR48_RS16210	COG2860	membrane
NYR48_RS16220	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NYR48_RS16225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NYR48_RS16230	COG2217	Heavy metal translocating P-type atpase
NYR48_RS16235	COG2217	Heavy metal translocating P-type atpase
NYR48_RS16240	COG2608	mercury ion transmembrane transporter activity
NYR48_RS16245	COG1937	Protein conserved in bacteria
NYR48_RS16250	COG0673	inositol 2-dehydrogenase activity
NYR48_RS16260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYR48_RS16265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NYR48_RS16270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYR48_RS16275	COG1126	abc transporter atp-binding protein
NYR48_RS16280	COG0765	amino acid transport
NYR48_RS16285	COG0765	amino acid transport
NYR48_RS16290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NYR48_RS16295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NYR48_RS16300	COG0454	-acetyltransferase
NYR48_RS16305	COG0583	DNA-binding transcription factor activity
NYR48_RS16310	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS16315	COG2732	(Barnase) inhibitor
NYR48_RS16320	COG2732	(Barnase) inhibitor
NYR48_RS16335	COG0557	exoribonuclease II activity
NYR48_RS16340	COG1647	Serine aminopeptidase, S33
NYR48_RS16345	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NYR48_RS16350	COG1476	TRANSCRIPTIONal
NYR48_RS16355	COG1396	sequence-specific DNA binding
NYR48_RS16360	COG1396	sequence-specific DNA binding
NYR48_RS16365	COG1733	regulation of RNA biosynthetic process
NYR48_RS16390	COG1131	(ABC) transporter
NYR48_RS16395	COG1174	glycine betaine transport
NYR48_RS16400	COG1732	Glycine betaine
NYR48_RS16405	COG1174	glycine betaine transport
NYR48_RS16410	COG0517	IMP dehydrogenase activity
NYR48_RS16410	COG1125	glycine betaine transport
NYR48_RS16415	COG1510	regulation of RNA biosynthetic process
NYR48_RS16420	COG1174	glycine betaine transport
NYR48_RS16425	COG1732	Glycine betaine
NYR48_RS16430	COG1174	glycine betaine transport
NYR48_RS16435	COG1125	glycine betaine transport
NYR48_RS16435	COG0517	IMP dehydrogenase activity
NYR48_RS16440	COG1510	regulation of RNA biosynthetic process
NYR48_RS16445	COG2095	MarC family integral membrane protein
NYR48_RS16450	COG3064	Membrane
NYR48_RS16455	COG4640	response to antibiotic
NYR48_RS16460	COG0456	acetyltransferase
NYR48_RS16480	COG0126	phosphoglycerate kinase activity
NYR48_RS16485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NYR48_RS16490	COG2390	Transcriptional regulator
NYR48_RS16495	COG2814	Major facilitator Superfamily
NYR48_RS16500	COG1609	Transcriptional regulator
NYR48_RS16505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYR48_RS16515	COG0583	DNA-binding transcription factor activity
NYR48_RS16520	COG0697	spore germination
NYR48_RS16525	COG1113	amino acid transport
NYR48_RS16535	COG1609	Transcriptional regulator
NYR48_RS16545	COG0561	phosphatase activity
NYR48_RS16550	COG1737	Transcriptional regulator
NYR48_RS16555	COG1070	Carbohydrate kinase
NYR48_RS16580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYR48_RS16585	COG2186	Transcriptional regulator
NYR48_RS16590	COG1620	l-lactate permease
NYR48_RS16595	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NYR48_RS16605	COG5039	Polysaccharide pyruvyl transferase
NYR48_RS16610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NYR48_RS16615	COG0110	maltose O-acetyltransferase activity
NYR48_RS16620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NYR48_RS16625	COG2244	polysaccharide biosynthetic process
NYR48_RS16630	COG1216	Glycosyl transferase, family 2
NYR48_RS16635	COG5039	Polysaccharide pyruvyl transferase
NYR48_RS16640	COG1216	Glycosyl transferase, family 2
NYR48_RS16650	COG0438	transferase activity, transferring glycosyl groups
NYR48_RS16655	COG1215	transferase activity, transferring glycosyl groups
NYR48_RS16660	COG0438	transferase activity, transferring glycosyl groups
NYR48_RS16665	COG1086	Polysaccharide biosynthesis protein
NYR48_RS16670	COG0489	protein tyrosine kinase activity
NYR48_RS16675	COG3944	biosynthesis protein
NYR48_RS16680	COG1396	sequence-specific DNA binding
NYR48_RS16685	COG2272	Belongs to the type-B carboxylesterase lipase family
NYR48_RS16695	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NYR48_RS16700	COG2364	Membrane
NYR48_RS16705	COG0456	acetyltransferase
NYR48_RS16710	COG3479	Phenolic acid decarboxylase
NYR48_RS16750	COG2223	nitrite transmembrane transporter activity
NYR48_RS16755	COG1609	Transcriptional regulator
NYR48_RS16765	COG0583	DNA-binding transcription factor activity
NYR48_RS16770	COG2828	Protein conserved in bacteria
NYR48_RS16775	COG0477	Major facilitator Superfamily
NYR48_RS16775	COG2814	Major facilitator Superfamily
NYR48_RS16780	COG1611	Belongs to the LOG family
NYR48_RS16785	COG1694	Mazg nucleotide pyrophosphohydrolase
NYR48_RS16790	COG0659	secondary active sulfate transmembrane transporter activity
NYR48_RS16795	COG0288	reversible hydration of carbon dioxide
NYR48_RS16800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NYR48_RS16805	COG4290	ribonuclease
NYR48_RS16810	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NYR48_RS16815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NYR48_RS16825	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NYR48_RS16835	COG1051	belongs to the nudix hydrolase family
NYR48_RS16840	COG0492	ferredoxin-NADP+ reductase activity
NYR48_RS16845	COG3883	PFAM NLP P60 protein
NYR48_RS16845	COG0791	NLP P60 protein
NYR48_RS16855	COG0457	Tetratricopeptide repeat
NYR48_RS16860	COG5002	protein histidine kinase activity
NYR48_RS16865	COG0745	RESPONSE REGULATOR receiver
NYR48_RS16875	COG1132	(ABC) transporter
NYR48_RS16880	COG0140	phosphoribosyl-ATP diphosphatase activity
NYR48_RS16880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NYR48_RS16905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NYR48_RS16920	COG4990	cell redox homeostasis
NYR48_RS16925	COG0110	maltose O-acetyltransferase activity
NYR48_RS16945	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NYR48_RS16955	COG2188	Transcriptional regulator
NYR48_RS16960	COG1309	transcriptional regulator
NYR48_RS16965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NYR48_RS16970	COG1950	PFAM Membrane protein of
NYR48_RS16975	COG1983	PspC domain protein
NYR48_RS16980	COG3595	metallopeptidase activity
NYR48_RS16995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NYR48_RS17005	COG4897	Protein conserved in bacteria
NYR48_RS17010	COG0574	Belongs to the PEP-utilizing enzyme family
NYR48_RS17010	COG3848	Pyruvate phosphate dikinase
NYR48_RS17015	COG1309	transcriptional regulator
NYR48_RS17020	COG2814	Major facilitator Superfamily
NYR48_RS17030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NYR48_RS17040	COG3409	Peptidoglycan-binding domain 1 protein
NYR48_RS17040	COG0793	Belongs to the peptidase S41A family
NYR48_RS17045	COG3420	alginic acid biosynthetic process
NYR48_RS17050	COG2177	Part of the ABC transporter FtsEX involved in
NYR48_RS17055	COG2884	Cell division ATP-binding protein ftsE
NYR48_RS17060	COG2010	Cytochrome c
NYR48_RS17065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NYR48_RS17080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NYR48_RS17095	COG1516	flagellar protein fliS
NYR48_RS17100	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NYR48_RS17105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NYR48_RS17125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NYR48_RS17130	COG4786	Flagellar basal body rod
NYR48_RS17130	COG1256	bacterial-type flagellum assembly
NYR48_RS17135	COG3418	PFAM FlgN family protein
NYR48_RS17140	COG2747	anti-sigma28 factor FlgM
NYR48_RS17150	COG1040	competence protein
NYR48_RS17160	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NYR48_RS17165	COG1307	EDD domain protein, DegV family
NYR48_RS17170	COG2197	response regulator
NYR48_RS17175	COG4585	Histidine kinase
NYR48_RS17180	COG1739	Uncharacterized protein family UPF0029
NYR48_RS17185	COG1316	TRANSCRIPTIONal
NYR48_RS17190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NYR48_RS17195	COG0438	transferase activity, transferring glycosyl groups
NYR48_RS17200	COG1215	transferase activity, transferring glycosyl groups
NYR48_RS17205	COG3206	protein involved in exopolysaccharide biosynthesis
NYR48_RS17210	COG3307	-O-antigen
NYR48_RS17215	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NYR48_RS17220	COG0438	transferase activity, transferring glycosyl groups
NYR48_RS17220	COG0297	glycogen (starch) synthase activity
NYR48_RS17225	COG2244	polysaccharide biosynthetic process
NYR48_RS17235	COG2247	cell wall binding repeat
NYR48_RS17235	COG0860	N-Acetylmuramoyl-L-alanine amidase
NYR48_RS17240	COG2385	sporulation resulting in formation of a cellular spore
NYR48_RS17240	COG2247	cell wall binding repeat
NYR48_RS17250	COG1316	TRANSCRIPTIONal
NYR48_RS17260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NYR48_RS17265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NYR48_RS17270	COG1134	teichoic acid transport
NYR48_RS17275	COG1682	transport, permease protein
NYR48_RS17280	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NYR48_RS17285	COG0463	Glycosyl transferase, family 2
NYR48_RS17290	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NYR48_RS17295	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NYR48_RS17300	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NYR48_RS17305	COG4193	domain, Protein
NYR48_RS17310	COG1482	cell wall glycoprotein biosynthetic process
NYR48_RS17315	COG0697	spore germination
NYR48_RS17320	COG0814	amino acid
NYR48_RS17330	COG1215	transferase activity, transferring glycosyl groups
NYR48_RS17335	COG2814	Major facilitator Superfamily
NYR48_RS17340	COG1316	TRANSCRIPTIONal
NYR48_RS17345	COG0561	phosphatase activity
NYR48_RS17350	COG2433	Pfam Transposase IS66
NYR48_RS17355	COG0791	NLP P60 protein
NYR48_RS17365	COG2843	Capsule synthesis protein
NYR48_RS17375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NYR48_RS17380	COG0697	spore germination
NYR48_RS17385	COG0814	amino acid
NYR48_RS17395	COG1609	Transcriptional regulator
NYR48_RS17400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NYR48_RS17410	COG1129	ABC transporter
NYR48_RS17415	COG1172	Belongs to the binding-protein-dependent transport system permease family
NYR48_RS17420	COG1879	ABC-type sugar transport system periplasmic component
NYR48_RS17425	COG3103	Sh3 type 3 domain protein
NYR48_RS17430	COG2249	NAD(P)H dehydrogenase (quinone) activity
NYR48_RS17435	COG3527	Alpha-acetolactate decarboxylase
NYR48_RS17440	COG0028	Belongs to the TPP enzyme family
NYR48_RS17445	COG0583	DNA-binding transcription factor activity
NYR48_RS17450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NYR48_RS17465	COG5337	Spore coat protein CotH
NYR48_RS17475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NYR48_RS17485	COG0405	Gamma-glutamyltransferase
NYR48_RS17490	COG1522	sequence-specific DNA binding
NYR48_RS17495	COG2059	Chromate
NYR48_RS17500	COG2059	Chromate
NYR48_RS17520	COG5444	nuclease activity
NYR48_RS17535	COG3878	Protein conserved in bacteria
NYR48_RS17540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NYR48_RS17545	COG4464	protein tyrosine phosphatase activity
NYR48_RS17550	COG0489	protein tyrosine kinase activity
NYR48_RS17555	COG3944	biosynthesis protein
NYR48_RS17565	COG4715	Zinc finger, swim domain protein
NYR48_RS17570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NYR48_RS17575	COG0561	phosphatase activity
NYR48_RS17580	COG1349	DNA-binding transcription factor activity
NYR48_RS17585	COG0629	single-stranded DNA binding
NYR48_RS17610	COG0457	Tetratricopeptide repeat
NYR48_RS17615	COG4786	Flagellar basal body rod
NYR48_RS17620	COG4786	Flagellar basal body rod
NYR48_RS17625	COG1077	Cell shape determining protein MreB Mrl
NYR48_RS17630	COG1609	Transcriptional regulator
NYR48_RS17635	COG1846	Transcriptional regulator
NYR48_RS17640	COG2814	Major facilitator Superfamily
NYR48_RS17645	COG1953	Uracil, thiamine, allantoin
NYR48_RS17650	COG0477	Major facilitator Superfamily
NYR48_RS17655	COG1335	isochorismatase
NYR48_RS17660	COG0004	ammonium transporteR
NYR48_RS17665	COG0347	Belongs to the P(II) protein family
NYR48_RS17670	COG0772	Belongs to the SEDS family
NYR48_RS17675	COG0671	phosphoesterase, PA-phosphatase related
NYR48_RS17685	COG0739	heme binding
NYR48_RS17690	COG1247	-acetyltransferase
NYR48_RS17705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NYR48_RS17715	COG0726	polysaccharide deacetylase
NYR48_RS17720	COG1959	2 iron, 2 sulfur cluster binding
NYR48_RS17735	COG0831	urea catabolic process
NYR48_RS17745	COG1994	Peptidase M50
NYR48_RS17750	COG0457	Tetratricopeptide repeat
NYR48_RS17760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NYR48_RS17770	COG2304	oxidoreductase activity
NYR48_RS17775	COG2304	oxidoreductase activity
NYR48_RS17780	COG2385	sporulation resulting in formation of a cellular spore
NYR48_RS17785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NYR48_RS17795	COG4836	Membrane
NYR48_RS17865	COG0698	ribose 5-phosphate isomerase
NYR48_RS17870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NYR48_RS17880	COG0009	L-threonylcarbamoyladenylate synthase
NYR48_RS17885	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NYR48_RS17905	COG2890	protein-(glutamine-N5) methyltransferase activity
NYR48_RS17910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NYR48_RS17915	COG0346	lactoylglutathione lyase activity
NYR48_RS17920	COG0789	Transcriptional regulator
NYR48_RS17925	COG0679	Auxin Efflux Carrier
NYR48_RS17930	COG0281	malic enzyme
NYR48_RS17945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NYR48_RS17955	COG1494	fructose-1,6-bisphosphatase
NYR48_RS17960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NYR48_RS17970	COG0191	fructose-bisphosphate aldolase activity
NYR48_RS17975	COG2204	response regulator
NYR48_RS17980	COG4821	SIS domain
NYR48_RS17995	COG2181	nitrate reductase activity
NYR48_RS17995	COG0247	lactate metabolic process
NYR48_RS18000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NYR48_RS18015	COG1132	(ABC) transporter
NYR48_RS18020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NYR48_RS18030	COG2181	nitrate reductase activity
NYR48_RS18035	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NYR48_RS18040	COG1140	nitrate reductase beta subunit
NYR48_RS18045	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NYR48_RS18050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NYR48_RS18060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NYR48_RS18065	COG2223	nitrite transmembrane transporter activity
NYR48_RS18075	COG4506	Protein conserved in bacteria
NYR48_RS18080	COG0457	Tetratricopeptide repeat
NYR48_RS18120	COG0010	Belongs to the arginase family
NYR48_RS18125	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NYR48_RS18130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NYR48_RS18145	COG1994	Peptidase M50
NYR48_RS18150	COG1942	4-Oxalocrotonate Tautomerase
NYR48_RS18155	COG1846	Transcriptional regulator
NYR48_RS18160	COG0531	amino acid
NYR48_RS18165	COG3465	dGTPase activity
NYR48_RS18170	COG1078	dGTPase activity
NYR48_RS18195	COG0583	DNA-binding transcription factor activity
NYR48_RS18200	COG2855	membrane
NYR48_RS18205	COG0280	phosphate acetyltransferase
NYR48_RS18215	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS18220	COG0436	Aminotransferase
NYR48_RS18250	COG2814	Major facilitator Superfamily
NYR48_RS18255	COG2814	Major facilitator Superfamily
NYR48_RS18260	COG0833	amino acid
NYR48_RS18265	COG4187	Peptidase family M20/M25/M40
NYR48_RS18270	COG1012	belongs to the aldehyde dehydrogenase family
NYR48_RS18275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NYR48_RS18285	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NYR48_RS18290	COG1091	dTDP-4-dehydrorhamnose reductase activity
NYR48_RS18295	COG1088	dTDP-glucose 4,6-dehydratase activity
NYR48_RS18300	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NYR48_RS18305	COG3980	spore coat polysaccharide biosynthesis protein
NYR48_RS18310	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NYR48_RS18315	COG2089	acid synthase
NYR48_RS18320	COG0456	acetyltransferase
NYR48_RS18325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NYR48_RS18330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NYR48_RS18335	COG0463	Glycosyl transferase, family 2
NYR48_RS18345	COG2363	Small membrane protein
NYR48_RS18350	COG2233	PERMEase
NYR48_RS18365	COG1216	Glycosyl transferase, family 2
NYR48_RS18380	COG1695	Transcriptional regulator
NYR48_RS18385	COG0351	phosphomethylpyrimidine kinase
NYR48_RS18395	COG1621	beta-fructofuranosidase activity
NYR48_RS18400	COG1263	PTS System
NYR48_RS18400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NYR48_RS18405	COG3711	transcriptional antiterminator
NYR48_RS18415	COG1404	Belongs to the peptidase S8 family
NYR48_RS18420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYR48_RS18430	COG0778	Nitroreductase
NYR48_RS18435	COG0772	Belongs to the SEDS family
NYR48_RS18440	COG0454	-acetyltransferase
NYR48_RS18460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NYR48_RS18465	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NYR48_RS18470	COG2261	transglycosylase associated protein
NYR48_RS18475	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NYR48_RS18480	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NYR48_RS18485	COG2246	polysaccharide biosynthetic process
NYR48_RS18490	COG1309	transcriptional regulator
NYR48_RS18510	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NYR48_RS18515	COG2837	iron assimilation
NYR48_RS18535	COG0583	DNA-binding transcription factor activity
NYR48_RS18545	COG1346	cytolysis
NYR48_RS18550	COG4895	conserved protein (DUF2196)
NYR48_RS18555	COG0789	Transcriptional regulator
NYR48_RS18560	COG5504	Zn-dependent protease
NYR48_RS18565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NYR48_RS18570	COG0346	lactoylglutathione lyase activity
NYR48_RS18575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NYR48_RS18580	COG1404	Belongs to the peptidase S8 family
NYR48_RS18585	COG1442	glycosyl transferase family 8
NYR48_RS18590	COG2357	RelA SpoT domain protein
NYR48_RS18595	COG1575	Belongs to the MenA family. Type 1 subfamily
NYR48_RS18610	COG1696	Membrane protein involved in D-alanine export
NYR48_RS18620	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NYR48_RS18625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NYR48_RS18630	COG1486	melibiose metabolic process
NYR48_RS18635	COG1447	Phosphotransferase system cellobiose-specific component IIA
NYR48_RS18640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NYR48_RS18645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NYR48_RS18650	COG3711	transcriptional antiterminator
NYR48_RS18650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NYR48_RS18665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYR48_RS18670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYR48_RS18680	COG0640	Transcriptional regulator
NYR48_RS18685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NYR48_RS18690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NYR48_RS18695	COG1447	Phosphotransferase system cellobiose-specific component IIA
NYR48_RS18700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NYR48_RS18705	COG2723	6-phospho-beta-galactosidase activity
NYR48_RS18710	COG1940	carbohydrate kinase activity
NYR48_RS18715	COG1482	cell wall glycoprotein biosynthetic process
NYR48_RS18725	COG0753	catalase activity
NYR48_RS18735	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NYR48_RS18740	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NYR48_RS18745	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NYR48_RS18750	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NYR48_RS18755	COG4988	ABC transporter
NYR48_RS18760	COG1294	oxidase, subunit
NYR48_RS18765	COG1271	oxidase subunit
NYR48_RS18770	COG3493	citrate carrier protein
NYR48_RS18775	COG0726	polysaccharide deacetylase
NYR48_RS18780	COG3842	ATPase activity
NYR48_RS18785	COG2508	Transcriptional regulator
NYR48_RS18790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NYR48_RS18800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NYR48_RS18815	COG4894	glucomannan catabolic process
NYR48_RS18820	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NYR48_RS18825	COG0500	methyltransferase
NYR48_RS18830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NYR48_RS18845	COG0753	catalase activity
NYR48_RS18845	COG0693	protein deglycase activity
NYR48_RS18850	COG2851	Citrate transporter
NYR48_RS18855	COG2273	Hydrolase Family 16
NYR48_RS18860	COG3711	transcriptional antiterminator
NYR48_RS18865	COG2270	Major facilitator Superfamily
NYR48_RS18870	COG0513	Belongs to the DEAD box helicase family
NYR48_RS18880	COG0697	spore germination
NYR48_RS18885	COG0589	response to stress
NYR48_RS18890	COG2723	6-phospho-beta-galactosidase activity
NYR48_RS18895	COG2190	(PTS) system
NYR48_RS18895	COG1263	PTS System
NYR48_RS18895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NYR48_RS18905	COG0494	nUDIX hydrolase
NYR48_RS18910	COG3507	Belongs to the glycosyl hydrolase 43 family
NYR48_RS18935	COG0010	Belongs to the arginase family
NYR48_RS18940	COG0833	amino acid
NYR48_RS18945	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NYR48_RS18950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NYR48_RS18960	COG2390	Transcriptional regulator
NYR48_RS18965	COG0561	phosphatase activity
NYR48_RS18995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NYR48_RS19000	COG5294	Protein conserved in bacteria
NYR48_RS19005	COG0577	efflux transmembrane transporter activity
NYR48_RS19010	COG1136	(ABC) transporter
NYR48_RS19015	COG2205	protein histidine kinase activity
NYR48_RS19020	COG0745	RESPONSE REGULATOR receiver
NYR48_RS19035	COG1082	Xylose isomerase domain protein TIM barrel
NYR48_RS19045	COG2814	Major facilitator Superfamily
NYR48_RS19075	COG1349	DNA-binding transcription factor activity
NYR48_RS19080	COG0667	Aldo Keto reductase
NYR48_RS19085	COG2814	Major facilitator Superfamily
NYR48_RS19100	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS19105	COG2197	response regulator
NYR48_RS19110	COG4585	Histidine kinase
NYR48_RS19115	COG3239	Fatty acid desaturase
NYR48_RS19120	COG1309	transcriptional regulator
NYR48_RS19125	COG1012	belongs to the aldehyde dehydrogenase family
NYR48_RS19130	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NYR48_RS19140	COG0640	Transcriptional regulator
NYR48_RS19145	COG2814	Major facilitator Superfamily
NYR48_RS19150	COG1714	RDD family
NYR48_RS19160	COG0501	Belongs to the peptidase M48B family
NYR48_RS19165	COG1715	Restriction endonuclease
NYR48_RS19170	COG0450	alkyl hydroperoxide reductase
NYR48_RS19175	COG3634	alkyl hydroperoxide reductase activity
NYR48_RS19180	COG3177	Filamentation induced by cAMP protein fic
NYR48_RS19185	COG1113	amino acid transport
NYR48_RS19195	COG2080	2 iron, 2 sulfur cluster binding
NYR48_RS19210	COG2068	MobA-Related Protein
NYR48_RS19215	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NYR48_RS19225	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NYR48_RS19245	COG2003	Belongs to the UPF0758 family
NYR48_RS19250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NYR48_RS19270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NYR48_RS19295	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NYR48_RS19300	COG0667	Aldo Keto reductase
NYR48_RS19305	COG0456	acetyltransferase
NYR48_RS19315	COG0457	Tetratricopeptide repeat
NYR48_RS19320	COG0010	Belongs to the arginase family
NYR48_RS19325	COG0833	amino acid
NYR48_RS19330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NYR48_RS19335	COG5658	integral membrane protein
NYR48_RS19340	COG0640	Transcriptional regulator
NYR48_RS19345	COG3829	transcription factor binding
NYR48_RS19355	COG0488	(ABC) transporter
NYR48_RS19370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NYR48_RS19375	COG3850	Histidine kinase
NYR48_RS19375	COG5002	protein histidine kinase activity
NYR48_RS19390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NYR48_RS19395	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NYR48_RS19400	COG4853	Protein conserved in bacteria
NYR48_RS19405	COG4863	YycH protein
NYR48_RS19410	COG5002	protein histidine kinase activity
NYR48_RS19415	COG0745	RESPONSE REGULATOR receiver
NYR48_RS19445	COG0346	lactoylglutathione lyase activity
NYR48_RS19450	COG0305	Participates in initiation and elongation during chromosome replication
NYR48_RS19465	COG3093	addiction module antidote protein HigA
NYR48_RS19470	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NYR48_RS19485	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NYR48_RS19490	COG0438	transferase activity, transferring glycosyl groups
NYR48_RS19510	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NYR48_RS19515	COG4241	membrane
NYR48_RS19525	COG5577	PFAM Coat F domain
NYR48_RS19530	COG1733	regulation of RNA biosynthetic process
NYR48_RS19545	COG0697	spore germination
NYR48_RS19550	COG1621	beta-fructofuranosidase activity
NYR48_RS19555	COG1621	beta-fructofuranosidase activity
NYR48_RS19560	COG1802	Transcriptional regulator
NYR48_RS19565	COG2318	DinB family
NYR48_RS19570	COG2211	Major facilitator Superfamily
NYR48_RS19575	COG0583	DNA-binding transcription factor activity
NYR48_RS19585	COG2814	Major facilitator Superfamily
NYR48_RS19590	COG0583	DNA-binding transcription factor activity
NYR48_RS19600	COG0778	Nitroreductase
NYR48_RS19605	COG1846	Transcriptional regulator
NYR48_RS19610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NYR48_RS19615	COG1846	Transcriptional regulator
NYR48_RS19620	COG2153	protein acetylation
NYR48_RS19630	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NYR48_RS19635	COG0583	DNA-binding transcription factor activity
NYR48_RS19640	COG1028	Short-chain dehydrogenase reductase Sdr
NYR48_RS19645	COG0546	phosphoglycolate phosphatase activity
NYR48_RS19655	COG0492	ferredoxin-NADP+ reductase activity
NYR48_RS19665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYR48_RS19670	COG0697	spore germination
NYR48_RS19675	COG1331	Highly conserved protein containing a thioredoxin domain
NYR48_RS19680	COG1266	CAAX protease self-immunity
NYR48_RS19685	COG0477	Major facilitator Superfamily
NYR48_RS19685	COG2814	Major facilitator Superfamily
NYR48_RS19690	COG0346	lactoylglutathione lyase activity
NYR48_RS19695	COG1609	Transcriptional regulator
NYR48_RS19700	COG0708	Exodeoxyribonuclease III
NYR48_RS19705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NYR48_RS19710	COG2169	Transcriptional regulator
NYR48_RS19720	COG0629	single-stranded DNA binding
NYR48_RS19730	COG0012	GTP binding
NYR48_RS19735	COG0243	molybdopterin cofactor binding
NYR48_RS19740	COG4481	Protein conserved in bacteria
NYR48_RS19745	COG3949	Membrane
NYR48_RS19760	COG1475	DNA binding
NYR48_RS19765	COG1192	Involved in chromosome partitioning
NYR48_RS19790	COG1847	R3H domain protein
NYR48_RS19795	COG0706	membrane insertase activity