locus-tag	class	description
LAZ97_RS00010	COG0592	DNA-directed DNA polymerase activity
LAZ97_RS00015	COG2501	S4 domain
LAZ97_RS00030	COG0187	DNA topoisomerase II activity
LAZ97_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LAZ97_RS00070	COG0516	GMP reductase activity
LAZ97_RS00070	COG0517	IMP dehydrogenase activity
LAZ97_RS00075	COG1686	Belongs to the peptidase S11 family
LAZ97_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
LAZ97_RS00105	COG1428	Deoxynucleoside kinase
LAZ97_RS00110	COG1428	Deoxynucleoside kinase
LAZ97_RS00115	COG1388	LysM domain
LAZ97_RS00115	COG3858	chitin binding
LAZ97_RS00120	COG1335	isochorismatase
LAZ97_RS00125	COG0590	tRNA wobble adenosine to inosine editing
LAZ97_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LAZ97_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LAZ97_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LAZ97_RS00195	COG3853	Toxic anion resistance protein (TelA)
LAZ97_RS00200	COG1982	Orn Lys Arg decarboxylase major
LAZ97_RS00210	COG3870	Protein conserved in bacteria
LAZ97_RS00215	COG1728	Protein conserved in bacteria
LAZ97_RS00220	COG0470	DNA polymerase III
LAZ97_RS00225	COG1774	PSP1 C-terminal conserved region
LAZ97_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LAZ97_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LAZ97_RS00250	COG2002	toxin-antitoxin pair type II binding
LAZ97_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LAZ97_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LAZ97_RS00260	COG0084	hydrolase, TatD family'
LAZ97_RS00265	COG3583	domain protein
LAZ97_RS00265	COG3584	3D domain protein
LAZ97_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LAZ97_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LAZ97_RS00285	COG4466	Protein conserved in bacteria
LAZ97_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LAZ97_RS00305	COG0251	oxidation-reduction process
LAZ97_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LAZ97_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LAZ97_RS00345	COG2002	toxin-antitoxin pair type II binding
LAZ97_RS00350	COG2244	polysaccharide biosynthetic process
LAZ97_RS00355	COG3956	TIGRFAM MazG family protein
LAZ97_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LAZ97_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LAZ97_RS00380	COG1098	S1 RNA binding domain
LAZ97_RS00395	COG2208	phosphoserine phosphatase activity
LAZ97_RS00400	COG2304	oxidoreductase activity
LAZ97_RS00405	COG0515	serine threonine protein kinase
LAZ97_RS00410	COG0037	tRNA processing
LAZ97_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LAZ97_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LAZ97_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LAZ97_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LAZ97_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LAZ97_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
LAZ97_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LAZ97_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LAZ97_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LAZ97_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LAZ97_RS00475	COG1396	sequence-specific DNA binding
LAZ97_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LAZ97_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LAZ97_RS00565	COG4463	regulation of RNA biosynthetic process
LAZ97_RS00570	COG3880	PFAM UvrB UvrC protein
LAZ97_RS00590	COG0542	response to heat
LAZ97_RS00595	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LAZ97_RS00600	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LAZ97_RS00605	COG4956	integral membrane protein (PIN domain superfamily)
LAZ97_RS00625	COG1045	serine acetyltransferase
LAZ97_RS00635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LAZ97_RS00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LAZ97_RS00645	COG3688	RNA-binding protein containing a PIN domain
LAZ97_RS00650	COG1595	DNA-templated transcription, initiation
LAZ97_RS00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LAZ97_RS00665	COG0250	Participates in transcription elongation, termination and antitermination
LAZ97_RS00690	COG2813	Specifically methylates the guanine in position
LAZ97_RS00705	COG1358	cellular component organization or biogenesis
LAZ97_RS00730	COG0596	Alpha beta hydrolase
LAZ97_RS00840	COG0201	protein transport
LAZ97_RS00850	COG0024	Methionine aminopeptidase
LAZ97_RS00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LAZ97_RS00890	COG1122	ATPase activity
LAZ97_RS00895	COG1122	ATPase activity
LAZ97_RS00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LAZ97_RS00920	COG2226	methyltransferase
LAZ97_RS00925	COG2318	DinB family
LAZ97_RS00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
LAZ97_RS00940	COG0489	protein tyrosine kinase activity
LAZ97_RS00950	COG2194	sulfuric ester hydrolase activity
LAZ97_RS00955	COG0726	polysaccharide deacetylase
LAZ97_RS01015	COG0738	Major facilitator superfamily
LAZ97_RS01020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LAZ97_RS01030	COG1063	alcohol dehydrogenase
LAZ97_RS01035	COG0659	secondary active sulfate transmembrane transporter activity
LAZ97_RS01040	COG0385	Bile acid
LAZ97_RS01045	COG2819	hydrolase of the alpha beta superfamily
LAZ97_RS01055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LAZ97_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LAZ97_RS01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LAZ97_RS01065	COG2207	Transcriptional regulator
LAZ97_RS01070	COG3876	Protein conserved in bacteria
LAZ97_RS01075	COG1472	Belongs to the glycosyl hydrolase 3 family
LAZ97_RS01080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LAZ97_RS01085	COG1263	PTS System
LAZ97_RS01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LAZ97_RS01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LAZ97_RS01100	COG1683	Conserved Protein
LAZ97_RS01130	COG1595	DNA-templated transcription, initiation
LAZ97_RS01135	COG5662	AntiSigma factor
LAZ97_RS01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LAZ97_RS01145	COG4856	YbbR-like protein
LAZ97_RS01185	COG1063	alcohol dehydrogenase
LAZ97_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS01230	COG1346	cytolysis
LAZ97_RS01235	COG1380	Effector of murein hydrolase LrgA
LAZ97_RS01240	COG1846	Transcriptional regulator
LAZ97_RS01245	COG1113	amino acid transport
LAZ97_RS01250	COG1011	Hydrolase
LAZ97_RS01255	COG4585	Histidine kinase
LAZ97_RS01260	COG2197	response regulator
LAZ97_RS01265	COG1131	(ABC) transporter
LAZ97_RS01305	COG0531	amino acid
LAZ97_RS01330	COG0584	glycerophosphoryl diester phosphodiesterase
LAZ97_RS01335	COG2271	Major facilitator Superfamily
LAZ97_RS01345	COG2368	4-hydroxyphenylacetate
LAZ97_RS01355	COG3409	Peptidoglycan-binding domain 1 protein
LAZ97_RS01370	COG0371	Dehydrogenase
LAZ97_RS01380	COG1183	phosphatidylcholine synthase activity
LAZ97_RS01385	COG0586	Pfam SNARE associated Golgi protein
LAZ97_RS01390	COG0688	phosphatidylethanolamine metabolic process
LAZ97_RS01405	COG1301	dicarboxylic acid transport
LAZ97_RS01410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LAZ97_RS01415	COG0833	amino acid
LAZ97_RS01420	COG2040	homocysteine
LAZ97_RS01425	COG1115	amino acid carrier protein
LAZ97_RS01430	COG2066	Belongs to the glutaminase family
LAZ97_RS01435	COG4191	Histidine kinase
LAZ97_RS01440	COG0784	Response regulator, receiver
LAZ97_RS01445	COG3173	Aminoglycoside phosphotransferase
LAZ97_RS01460	COG3773	Cell wall hydrolase
LAZ97_RS01465	COG3540	Alkaline phosphatase
LAZ97_RS01470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LAZ97_RS01475	COG0805	protein transport
LAZ97_RS01485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LAZ97_RS01490	COG0477	Major facilitator Superfamily
LAZ97_RS01495	COG1309	transcriptional regulator
LAZ97_RS01500	COG0252	asparaginase activity
LAZ97_RS01505	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LAZ97_RS01510	COG1405	negative regulation of cell septum assembly
LAZ97_RS01510	COG3012	SEC-C Motif Domain Protein
LAZ97_RS01515	COG0667	Aldo Keto reductase
LAZ97_RS01525	COG1595	DNA-templated transcription, initiation
LAZ97_RS01530	COG1595	DNA-templated transcription, initiation
LAZ97_RS01535	COG1876	peptidase activity
LAZ97_RS01540	COG0457	Tetratricopeptide repeat
LAZ97_RS01545	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS01560	COG0803	Belongs to the bacterial solute-binding protein 9 family
LAZ97_RS01565	COG1121	(ABC) transporter
LAZ97_RS01570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LAZ97_RS01575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LAZ97_RS01580	COG2310	stress, protein
LAZ97_RS01585	COG2310	stress, protein
LAZ97_RS01590	COG2310	stress, protein
LAZ97_RS01595	COG0861	Integral membrane protein TerC family
LAZ97_RS01605	COG3853	Toxic anion resistance protein (TelA)
LAZ97_RS01610	COG0477	Major facilitator Superfamily
LAZ97_RS01615	COG0517	IMP dehydrogenase activity
LAZ97_RS01615	COG4175	Glycine betaine
LAZ97_RS01620	COG4176	ABC-type proline glycine betaine transport system permease component
LAZ97_RS01625	COG2113	Glycine betaine
LAZ97_RS01630	COG1473	amidohydrolase
LAZ97_RS01635	COG1288	antiporter activity
LAZ97_RS01645	COG0366	Alpha amylase catalytic
LAZ97_RS01655	COG2814	Major facilitator Superfamily
LAZ97_RS01660	COG1846	Transcriptional regulator
LAZ97_RS01665	COG1280	lysine exporter protein (LysE YggA)
LAZ97_RS01670	COG3403	YqcI/YcgG family
LAZ97_RS01675	COG1113	amino acid transport
LAZ97_RS01680	COG3665	Urea carboxylase-associated protein
LAZ97_RS01695	COG1660	Displays ATPase and GTPase activities
LAZ97_RS01705	COG2271	Major facilitator Superfamily
LAZ97_RS01710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LAZ97_RS01715	COG3458	cephalosporin-C deacetylase activity
LAZ97_RS01720	COG3541	Predicted nucleotidyltransferase
LAZ97_RS01725	COG0506	proline dehydrogenase activity
LAZ97_RS01730	COG1012	belongs to the aldehyde dehydrogenase family
LAZ97_RS01735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LAZ97_RS01740	COG2508	Transcriptional regulator
LAZ97_RS01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LAZ97_RS01750	COG1587	Uroporphyrinogen-III synthase
LAZ97_RS01755	COG2146	nitrite reductase [NAD(P)H] activity
LAZ97_RS01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LAZ97_RS01765	COG0243	molybdopterin cofactor binding
LAZ97_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LAZ97_RS01775	COG2223	nitrite transmembrane transporter activity
LAZ97_RS01780	COG0523	cobalamin synthesis protein
LAZ97_RS01785	COG1063	alcohol dehydrogenase
LAZ97_RS01790	COG1714	RDD family
LAZ97_RS01800	COG2723	6-phospho-beta-galactosidase activity
LAZ97_RS01810	COG3209	COG3209 Rhs family protein
LAZ97_RS01815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LAZ97_RS01820	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LAZ97_RS01825	COG1733	regulation of RNA biosynthetic process
LAZ97_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS01850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS01855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS01860	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LAZ97_RS01875	COG2364	Membrane
LAZ97_RS01880	COG1126	abc transporter atp-binding protein
LAZ97_RS01885	COG0765	amino acid transport
LAZ97_RS01890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LAZ97_RS01895	COG0583	DNA-binding transcription factor activity
LAZ97_RS01900	COG0163	prenyltransferase activity
LAZ97_RS01905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LAZ97_RS01920	COG3104	oligopeptide transport
LAZ97_RS01925	COG5434	Belongs to the glycosyl hydrolase 28 family
LAZ97_RS01935	COG0697	spore germination
LAZ97_RS01945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LAZ97_RS01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LAZ97_RS01955	COG0456	acetyltransferase
LAZ97_RS01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LAZ97_RS01965	COG0765	amino acid transport
LAZ97_RS01970	COG1126	abc transporter atp-binding protein
LAZ97_RS01975	COG1473	amidohydrolase
LAZ97_RS01980	COG2079	MmgE PrpD family protein
LAZ97_RS01985	COG1136	(ABC) transporter
LAZ97_RS01990	COG0577	efflux transmembrane transporter activity
LAZ97_RS01995	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS02000	COG5002	protein histidine kinase activity
LAZ97_RS02000	COG3850	Histidine kinase
LAZ97_RS02005	COG0457	Tetratricopeptide repeat
LAZ97_RS02020	COG0527	aspartate kinase activity
LAZ97_RS02025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LAZ97_RS02030	COG4605	iron ion homeostasis
LAZ97_RS02035	COG4604	ABC transporter, ATP-binding protein
LAZ97_RS02040	COG4607	ABC-type enterochelin transport system periplasmic component
LAZ97_RS02045	COG2814	Major facilitator Superfamily
LAZ97_RS02050	COG1309	transcriptional regulator
LAZ97_RS02055	COG0778	Nitroreductase
LAZ97_RS02060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LAZ97_RS02065	COG0640	Transcriptional regulator
LAZ97_RS02070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LAZ97_RS02075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LAZ97_RS02080	COG1012	belongs to the aldehyde dehydrogenase family
LAZ97_RS02085	COG4975	Glucose uptake
LAZ97_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS02095	COG4549	nuclear export factor GLE1
LAZ97_RS02100	COG1276	copper resistance
LAZ97_RS02100	COG2372	response to copper ion
LAZ97_RS02105	COG1349	DNA-binding transcription factor activity
LAZ97_RS02115	COG2213	PTS system mannitol-specific
LAZ97_RS02120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LAZ97_RS02130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LAZ97_RS02140	COG0561	phosphatase activity
LAZ97_RS02150	COG1914	H( )-stimulated, divalent metal cation uptake system
LAZ97_RS02160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LAZ97_RS02165	COG1984	allophanate hydrolase subunit 2
LAZ97_RS02170	COG1414	Transcriptional regulator
LAZ97_RS02175	COG2755	lipolytic protein G-D-S-L family
LAZ97_RS02185	COG2329	Antibiotic biosynthesis monooxygenase
LAZ97_RS02190	COG0768	penicillin binding
LAZ97_RS02195	COG4989	oxidoreductase activity
LAZ97_RS02200	COG3711	transcriptional antiterminator
LAZ97_RS02205	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS02215	COG1917	Cupin 2, conserved barrel domain protein
LAZ97_RS02220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LAZ97_RS02225	COG3871	stress protein (general stress protein 26)
LAZ97_RS02235	COG2814	Major facilitator Superfamily
LAZ97_RS02240	COG1522	sequence-specific DNA binding
LAZ97_RS02245	COG0551	DNA topoisomerase type I activity
LAZ97_RS02245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LAZ97_RS02250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LAZ97_RS02255	COG3706	GGDEF domain
LAZ97_RS02260	COG5298	Protein conserved in bacteria
LAZ97_RS02265	COG1215	transferase activity, transferring glycosyl groups
LAZ97_RS02275	COG0531	amino acid
LAZ97_RS02280	COG0494	nUDIX hydrolase
LAZ97_RS02285	COG0028	Belongs to the TPP enzyme family
LAZ97_RS02305	COG0457	Tetratricopeptide repeat
LAZ97_RS02330	COG1914	H( )-stimulated, divalent metal cation uptake system
LAZ97_RS02350	COG2076	Multidrug Resistance protein
LAZ97_RS02355	COG2217	Heavy metal translocating P-type atpase
LAZ97_RS02365	COG0662	Cupin 2, conserved barrel domain protein
LAZ97_RS02370	COG2329	Antibiotic biosynthesis monooxygenase
LAZ97_RS02375	COG3546	catalase activity
LAZ97_RS02380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LAZ97_RS02385	COG3290	protein histidine kinase activity
LAZ97_RS02390	COG4565	transcriptional regulatory protein
LAZ97_RS02395	COG1301	dicarboxylic acid transport
LAZ97_RS02400	COG0628	permease
LAZ97_RS02410	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LAZ97_RS02420	COG1960	acyl-CoA dehydrogenase activity
LAZ97_RS02435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LAZ97_RS02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LAZ97_RS02450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LAZ97_RS02455	COG0513	Belongs to the DEAD box helicase family
LAZ97_RS02460	COG3402	PFAM membrane-flanked domain
LAZ97_RS02465	COG3428	Bacterial PH domain
LAZ97_RS02470	COG0705	Rhomboid family
LAZ97_RS02480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LAZ97_RS02485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LAZ97_RS02490	COG0864	Transcriptional regulator
LAZ97_RS02495	COG2337	Toxic component of a toxin-antitoxin (TA) module
LAZ97_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
LAZ97_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
LAZ97_RS02510	COG2172	sigma factor antagonist activity
LAZ97_RS02515	COG2208	phosphoserine phosphatase activity
LAZ97_RS02520	COG1366	Belongs to the anti-sigma-factor antagonist family
LAZ97_RS02530	COG1191	sigma factor activity
LAZ97_RS02535	COG2208	phosphoserine phosphatase activity
LAZ97_RS02540	COG2183	response to ionizing radiation
LAZ97_RS02590	COG0582	viral genome integration into host DNA
LAZ97_RS02595	COG2856	Zn peptidase
LAZ97_RS02600	COG1396	sequence-specific DNA binding
LAZ97_RS02625	COG1674	ftsk spoiiie
LAZ97_RS02630	COG2946	Replication initiation factor
LAZ97_RS02685	COG0433	COG0433 Predicted ATPase
LAZ97_RS02695	COG5644	endopeptidase inhibitor activity
LAZ97_RS02700	COG0741	lytic transglycosylase activity
LAZ97_RS02700	COG0791	NLP P60 protein
LAZ97_RS02720	COG0457	Tetratricopeptide repeat
LAZ97_RS02725	COG2249	NAD(P)H dehydrogenase (quinone) activity
LAZ97_RS02745	COG0477	Major facilitator Superfamily
LAZ97_RS02760	COG2030	dehydratase
LAZ97_RS02775	COG1959	2 iron, 2 sulfur cluster binding
LAZ97_RS02780	COG2910	NAD(P)H-binding
LAZ97_RS02790	COG1309	transcriptional regulator
LAZ97_RS02795	COG3239	Fatty acid desaturase
LAZ97_RS02805	COG1278	Cold shock
LAZ97_RS02810	COG1329	Transcriptional regulator
LAZ97_RS02815	COG1794	racemase activity, acting on amino acids and derivatives
LAZ97_RS02830	COG3621	Patatin-like phospholipase
LAZ97_RS02840	COG0662	Cupin 2, conserved barrel domain protein
LAZ97_RS02855	COG0277	FAD linked oxidase domain protein
LAZ97_RS02880	COG0662	Cupin 2, conserved barrel domain protein
LAZ97_RS02885	COG2318	DinB family
LAZ97_RS02890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LAZ97_RS02915	COG1064	alcohol dehydrogenase
LAZ97_RS02920	COG0789	Transcriptional regulator
LAZ97_RS02930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LAZ97_RS02945	COG2814	Major facilitator Superfamily
LAZ97_RS02950	COG1309	transcriptional regulator
LAZ97_RS02955	COG5577	PFAM Coat F domain
LAZ97_RS02965	COG1063	alcohol dehydrogenase
LAZ97_RS02970	COG5577	PFAM Coat F domain
LAZ97_RS02985	COG4585	Histidine kinase
LAZ97_RS02990	COG2197	response regulator
LAZ97_RS02995	COG2409	Drug exporters of the RND superfamily
LAZ97_RS03000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LAZ97_RS03005	COG0488	(ABC) transporter
LAZ97_RS03010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LAZ97_RS03015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAZ97_RS03025	COG2814	Major facilitator Superfamily
LAZ97_RS03030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LAZ97_RS03040	COG0730	response to heat
LAZ97_RS03045	COG0456	acetyltransferase
LAZ97_RS03050	COG4978	Transcriptional regulator
LAZ97_RS03050	COG0789	Transcriptional regulator
LAZ97_RS03055	COG0697	spore germination
LAZ97_RS03060	COG1051	belongs to the nudix hydrolase family
LAZ97_RS03070	COG0473	3-isopropylmalate dehydrogenase activity
LAZ97_RS03075	COG1802	Transcriptional regulator
LAZ97_RS03080	COG1819	glycosyl
LAZ97_RS03095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LAZ97_RS03105	COG1388	LysM domain
LAZ97_RS03110	COG2814	Major facilitator Superfamily
LAZ97_RS03115	COG2188	Transcriptional regulator
LAZ97_RS03120	COG2186	Transcriptional regulator
LAZ97_RS03125	COG2807	transmembrane transport
LAZ97_RS03130	COG2076	Multidrug Resistance protein
LAZ97_RS03135	COG2076	Multidrug Resistance protein
LAZ97_RS03140	COG1309	transcriptional regulator
LAZ97_RS03145	COG0531	amino acid
LAZ97_RS03155	COG3832	glyoxalase III activity
LAZ97_RS03160	COG0604	alcohol dehydrogenase
LAZ97_RS03170	COG2814	Major facilitator Superfamily
LAZ97_RS03210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LAZ97_RS03215	COG0802	atpase or kinase
LAZ97_RS03220	COG1214	PFAM Peptidase M22, glycoprotease
LAZ97_RS03225	COG0456	acetyltransferase
LAZ97_RS03230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LAZ97_RS03235	COG0488	(ABC) transporter
LAZ97_RS03250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LAZ97_RS03255	COG0805	protein transport
LAZ97_RS03265	COG1266	CAAX protease self-immunity
LAZ97_RS03280	COG0156	8-amino-7-oxononanoate synthase activity
LAZ97_RS03300	COG3403	YqcI/YcgG family
LAZ97_RS03315	COG2814	Major facilitator Superfamily
LAZ97_RS03320	COG0457	Tetratricopeptide repeat
LAZ97_RS03325	COG1063	alcohol dehydrogenase
LAZ97_RS03330	COG2211	Major facilitator Superfamily
LAZ97_RS03335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LAZ97_RS03345	COG1842	Phage shock protein A
LAZ97_RS03350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LAZ97_RS03355	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LAZ97_RS03360	COG4260	virion core protein, lumpy skin disease virus
LAZ97_RS03365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LAZ97_RS03365	COG2755	lipolytic protein G-D-S-L family
LAZ97_RS03375	COG1595	DNA-templated transcription, initiation
LAZ97_RS03380	COG1063	alcohol dehydrogenase
LAZ97_RS03385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LAZ97_RS03390	COG0823	Involved in the tonB-independent uptake of proteins
LAZ97_RS03405	COG2132	Multicopper oxidase
LAZ97_RS03410	COG1113	amino acid transport
LAZ97_RS03415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LAZ97_RS03420	COG0714	Associated with various cellular activities
LAZ97_RS03425	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LAZ97_RS03430	COG1305	Transglutaminase-like
LAZ97_RS03460	COG2211	Major facilitator Superfamily
LAZ97_RS03475	COG2252	PERMEase
LAZ97_RS03480	COG3064	Membrane
LAZ97_RS03500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LAZ97_RS03505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LAZ97_RS03510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LAZ97_RS03515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LAZ97_RS03520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LAZ97_RS03535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LAZ97_RS03545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LAZ97_RS03550	COG0138	bifunctional purine biosynthesis protein purh
LAZ97_RS03555	COG0151	Belongs to the GarS family
LAZ97_RS03565	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LAZ97_RS03570	COG1470	cell adhesion involved in biofilm formation
LAZ97_RS03575	COG4496	protein, YerC YecD
LAZ97_RS03580	COG0069	glutamate synthase activity
LAZ97_RS03590	COG0210	DNA helicase
LAZ97_RS03600	COG4851	CamS sex pheromone cAM373 precursor
LAZ97_RS03605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LAZ97_RS03610	COG1285	pathogenesis
LAZ97_RS03615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LAZ97_RS03635	COG1309	transcriptional regulator
LAZ97_RS03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LAZ97_RS03645	COG1597	lipid kinase activity
LAZ97_RS03650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LAZ97_RS03655	COG2197	response regulator
LAZ97_RS03665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS03675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LAZ97_RS03685	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS03690	COG1131	(ABC) transporter
LAZ97_RS03720	COG5444	nuclease activity
LAZ97_RS03730	COG5444	nuclease activity
LAZ97_RS03760	COG3546	catalase activity
LAZ97_RS03765	COG0454	-acetyltransferase
LAZ97_RS03775	COG2323	membrane
LAZ97_RS03780	COG2329	Antibiotic biosynthesis monooxygenase
LAZ97_RS03785	COG0346	lactoylglutathione lyase activity
LAZ97_RS03790	COG1366	Belongs to the anti-sigma-factor antagonist family
LAZ97_RS03795	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LAZ97_RS03800	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LAZ97_RS03805	COG4208	sulfate ABC transporter
LAZ97_RS03815	COG5583	Uncharacterized small protein (DUF2292)
LAZ97_RS03820	COG0196	riboflavin kinase activity
LAZ97_RS03825	COG0670	Belongs to the BI1 family
LAZ97_RS03830	COG1846	Transcriptional regulator
LAZ97_RS03835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LAZ97_RS03845	COG2124	cytochrome p450
LAZ97_RS03845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LAZ97_RS03860	COG1131	(ABC) transporter
LAZ97_RS03870	COG1368	sulfuric ester hydrolase activity
LAZ97_RS03875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LAZ97_RS03880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LAZ97_RS03885	COG1442	glycosyl transferase family 8
LAZ97_RS03890	COG1216	Glycosyl transferase, family 2
LAZ97_RS03895	COG1442	glycosyl transferase family 8
LAZ97_RS03900	COG2223	nitrite transmembrane transporter activity
LAZ97_RS03905	COG0531	amino acid
LAZ97_RS03910	COG1012	belongs to the aldehyde dehydrogenase family
LAZ97_RS03915	COG0840	transmembrane signaling receptor activity
LAZ97_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS03925	COG0457	Tetratricopeptide repeat
LAZ97_RS03925	COG0463	Glycosyl transferase, family 2
LAZ97_RS03930	COG0488	(ABC) transporter
LAZ97_RS03935	COG0789	Transcriptional regulator
LAZ97_RS03940	COG2814	Major facilitator Superfamily
LAZ97_RS03945	COG0488	(ABC) transporter
LAZ97_RS03950	COG0513	Belongs to the DEAD box helicase family
LAZ97_RS03960	COG2130	NADP-dependent
LAZ97_RS03975	COG3866	Pectate lyase
LAZ97_RS03980	COG0471	metal ion transport
LAZ97_RS03995	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS03995	COG2972	Histidine kinase
LAZ97_RS04015	COG2851	Citrate transporter
LAZ97_RS04020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LAZ97_RS04025	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LAZ97_RS04035	COG2258	MOSC domain
LAZ97_RS04055	COG0024	Methionine aminopeptidase
LAZ97_RS04060	COG1263	PTS System
LAZ97_RS04060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LAZ97_RS04070	COG1368	sulfuric ester hydrolase activity
LAZ97_RS04080	COG0071	Belongs to the small heat shock protein (HSP20) family
LAZ97_RS04095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LAZ97_RS04095	COG1263	PTS System
LAZ97_RS04100	COG0366	Alpha amylase catalytic
LAZ97_RS04105	COG2188	Transcriptional regulator
LAZ97_RS04110	COG0778	Nitroreductase
LAZ97_RS04125	COG0737	Belongs to the 5'-nucleotidase family
LAZ97_RS04130	COG0693	protein deglycase activity
LAZ97_RS04135	COG1609	Transcriptional regulator
LAZ97_RS04150	COG2814	Major facilitator Superfamily
LAZ97_RS04160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LAZ97_RS04165	COG4980	gas vesicle protein
LAZ97_RS04170	COG1295	ribonuclease BN
LAZ97_RS04180	COG0477	Major facilitator Superfamily
LAZ97_RS04185	COG0387	Pfam Sodium calcium exchanger
LAZ97_RS04195	COG0668	transmembrane transport
LAZ97_RS04200	COG0535	radical SAM domain protein
LAZ97_RS04210	COG0726	polysaccharide deacetylase
LAZ97_RS04215	COG2084	Dehydrogenase
LAZ97_RS04225	COG0598	Magnesium transport protein CorA
LAZ97_RS04230	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LAZ97_RS04235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LAZ97_RS04245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LAZ97_RS04250	COG4637	Psort location Cytoplasmic, score
LAZ97_RS04255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LAZ97_RS04260	COG0022	dehydrogenase e1 component
LAZ97_RS04265	COG0508	dehydrogenase complex catalyzes the overall conversion of
LAZ97_RS04270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LAZ97_RS04275	COG3284	Transcriptional regulator
LAZ97_RS04285	COG1486	melibiose metabolic process
LAZ97_RS04290	COG1737	Transcriptional regulator
LAZ97_RS04295	COG1263	PTS System
LAZ97_RS04295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LAZ97_RS04300	COG1132	(ABC) transporter
LAZ97_RS04305	COG1132	(ABC) transporter
LAZ97_RS04310	COG2259	Doxx family
LAZ97_RS04315	COG2514	catechol 2,3-dioxygenase activity
LAZ97_RS04325	COG1695	Transcriptional regulator
LAZ97_RS04330	COG2249	NAD(P)H dehydrogenase (quinone) activity
LAZ97_RS04335	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LAZ97_RS04340	COG0574	Belongs to the PEP-utilizing enzyme family
LAZ97_RS04340	COG3848	Pyruvate phosphate dikinase
LAZ97_RS04350	COG2732	(Barnase) inhibitor
LAZ97_RS04355	COG2318	DinB family
LAZ97_RS04360	COG2814	Major facilitator Superfamily
LAZ97_RS04365	COG1846	Transcriptional regulator
LAZ97_RS04370	COG0392	lysyltransferase activity
LAZ97_RS04370	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LAZ97_RS04375	COG0384	phenazine biosynthesis protein PhzF
LAZ97_RS04380	COG0778	Nitroreductase
LAZ97_RS04395	COG1090	epimerase
LAZ97_RS04410	COG2814	Major facilitator Superfamily
LAZ97_RS04420	COG3591	Belongs to the peptidase S1B family
LAZ97_RS04435	COG3103	Sh3 type 3 domain protein
LAZ97_RS04440	COG5658	integral membrane protein
LAZ97_RS04445	COG0596	Alpha beta hydrolase
LAZ97_RS04450	COG0463	Glycosyl transferase, family 2
LAZ97_RS04455	COG4485	Bacterial membrane protein, YfhO
LAZ97_RS04460	COG1988	membrane-bound metal-dependent
LAZ97_RS04465	COG1194	a g-specific adenine glycosylase
LAZ97_RS04475	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS04495	COG1132	(ABC) transporter
LAZ97_RS04500	COG4129	membrane
LAZ97_RS04510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LAZ97_RS04515	COG0735	belongs to the Fur family
LAZ97_RS04660	COG3340	Belongs to the peptidase S51 family
LAZ97_RS04670	COG0277	FAD linked oxidase domain protein
LAZ97_RS04680	COG0747	negative chemotaxis
LAZ97_RS04685	COG0601	transmembrane transport
LAZ97_RS04690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LAZ97_RS04695	COG0444	Belongs to the ABC transporter superfamily
LAZ97_RS04700	COG4608	Belongs to the ABC transporter superfamily
LAZ97_RS04705	COG0753	catalase activity
LAZ97_RS04715	COG1116	anion transmembrane transporter activity
LAZ97_RS04720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LAZ97_RS04725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LAZ97_RS04750	COG1476	TRANSCRIPTIONal
LAZ97_RS04760	COG3382	B3 4 domain protein
LAZ97_RS04765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LAZ97_RS04775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LAZ97_RS04780	COG0789	Transcriptional regulator
LAZ97_RS04785	COG1664	Polymer-forming cytoskeletal
LAZ97_RS04790	COG1664	Polymer-forming cytoskeletal
LAZ97_RS04795	COG2766	serine protein kinase
LAZ97_RS04805	COG1846	Transcriptional regulator
LAZ97_RS04810	COG1566	PFAM secretion protein HlyD family protein
LAZ97_RS04815	COG2814	Major facilitator Superfamily
LAZ97_RS04820	COG0655	NAD(P)H dehydrogenase (quinone) activity
LAZ97_RS04835	COG1725	Transcriptional regulator
LAZ97_RS04840	COG1131	(ABC) transporter
LAZ97_RS04845	COG1131	(ABC) transporter
LAZ97_RS04850	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LAZ97_RS04860	COG1278	Cold shock
LAZ97_RS04865	COG1464	Belongs to the NlpA lipoprotein family
LAZ97_RS04870	COG3706	GGDEF domain
LAZ97_RS04875	COG1823	symporter activity
LAZ97_RS04895	COG5577	PFAM Coat F domain
LAZ97_RS04900	COG0737	Belongs to the 5'-nucleotidase family
LAZ97_RS04900	COG1525	nuclease
LAZ97_RS04900	COG4085	toxin activity
LAZ97_RS04905	COG3764	Sortase (surface protein transpeptidase)
LAZ97_RS04910	COG0564	pseudouridine synthase activity
LAZ97_RS04920	COG0517	IMP dehydrogenase activity
LAZ97_RS04925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LAZ97_RS04930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LAZ97_RS04930	COG3153	acetyltransferase
LAZ97_RS04940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LAZ97_RS04945	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LAZ97_RS04950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LAZ97_RS04960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LAZ97_RS04965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LAZ97_RS04970	COG4585	Histidine kinase
LAZ97_RS04970	COG2203	Gaf domain
LAZ97_RS04975	COG2197	response regulator
LAZ97_RS04980	COG0431	NADPH-dependent FMN reductase
LAZ97_RS04995	COG1388	LysM domain
LAZ97_RS04995	COG0791	NLP P60 protein
LAZ97_RS05000	COG1959	2 iron, 2 sulfur cluster binding
LAZ97_RS05010	COG2719	SpoVR family
LAZ97_RS05015	COG1785	Belongs to the alkaline phosphatase family
LAZ97_RS05020	COG1388	LysM domain
LAZ97_RS05020	COG0791	NLP P60 protein
LAZ97_RS05025	COG0583	DNA-binding transcription factor activity
LAZ97_RS05030	COG0372	Belongs to the citrate synthase family
LAZ97_RS05035	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS05040	COG0531	amino acid
LAZ97_RS05045	COG0733	neurotransmitter:sodium symporter activity
LAZ97_RS05060	COG1595	DNA-templated transcription, initiation
LAZ97_RS05065	COG0204	Acyl-transferase
LAZ97_RS05070	COG1253	flavin adenine dinucleotide binding
LAZ97_RS05075	COG0789	Transcriptional regulator
LAZ97_RS05080	COG0436	Aminotransferase
LAZ97_RS05085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LAZ97_RS05090	COG1253	flavin adenine dinucleotide binding
LAZ97_RS05095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LAZ97_RS05100	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LAZ97_RS05105	COG0584	glycerophosphoryl diester phosphodiesterase
LAZ97_RS05115	COG0668	transmembrane transport
LAZ97_RS05120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LAZ97_RS05125	COG0726	polysaccharide deacetylase
LAZ97_RS05130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LAZ97_RS05135	COG3226	Transcriptional regulator
LAZ97_RS05145	COG0589	response to stress
LAZ97_RS05150	COG1132	(ABC) transporter
LAZ97_RS05155	COG1132	(ABC) transporter
LAZ97_RS05160	COG0702	epimerase
LAZ97_RS05180	COG0189	ligase activity
LAZ97_RS05185	COG0189	ligase activity
LAZ97_RS05200	COG4335	DNA alkylation repair
LAZ97_RS05205	COG0561	phosphatase activity
LAZ97_RS05210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LAZ97_RS05220	COG0475	glutathione-regulated potassium exporter activity
LAZ97_RS05225	COG0490	domain, Protein
LAZ97_RS05235	COG1024	Enoyl-CoA hydratase
LAZ97_RS05245	COG4152	abc transporter atp-binding protein
LAZ97_RS05250	COG1668	transmembrane transport
LAZ97_RS05255	COG0420	3'-5' exonuclease activity
LAZ97_RS05260	COG4717	serine-type aminopeptidase activity
LAZ97_RS05275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LAZ97_RS05310	COG4980	gas vesicle protein
LAZ97_RS05325	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LAZ97_RS05330	COG0537	adenosine 5'-monophosphoramidase activity
LAZ97_RS05335	COG1131	(ABC) transporter
LAZ97_RS05340	COG4473	ABC transporter
LAZ97_RS05350	COG1473	amidohydrolase
LAZ97_RS05355	COG3069	C4-dicarboxylate transmembrane transporter activity
LAZ97_RS05360	COG2329	Antibiotic biosynthesis monooxygenase
LAZ97_RS05365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LAZ97_RS05375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LAZ97_RS05380	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LAZ97_RS05385	COG1309	transcriptional regulator
LAZ97_RS05390	COG1511	domain protein
LAZ97_RS05395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LAZ97_RS05405	COG1363	Peptidase, m42
LAZ97_RS05410	COG1301	dicarboxylic acid transport
LAZ97_RS05420	COG1234	tRNA 3'-trailer cleavage
LAZ97_RS05425	COG0095	Lipoate-protein ligase
LAZ97_RS05430	COG0702	epimerase
LAZ97_RS05435	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS05445	COG0501	Belongs to the peptidase M48B family
LAZ97_RS05450	COG1404	Belongs to the peptidase S8 family
LAZ97_RS05460	COG0406	alpha-ribazole phosphatase activity
LAZ97_RS05465	COG0183	Belongs to the thiolase family
LAZ97_RS05470	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS05475	COG1268	BioY protein
LAZ97_RS05480	COG0840	transmembrane signaling receptor activity
LAZ97_RS05485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LAZ97_RS05485	COG0723	plastoquinol--plastocyanin reductase activity
LAZ97_RS05490	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS05500	COG4903	ComK protein
LAZ97_RS05510	COG5646	InterPro IPR014922
LAZ97_RS05535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LAZ97_RS05550	COG0398	Pfam SNARE associated Golgi protein
LAZ97_RS05555	COG0681	Belongs to the peptidase S26 family
LAZ97_RS05560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LAZ97_RS05565	COG1846	Transcriptional regulator
LAZ97_RS05570	COG3180	Ammonia monooxygenase
LAZ97_RS05575	COG2814	Major facilitator Superfamily
LAZ97_RS05585	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LAZ97_RS05590	COG2323	membrane
LAZ97_RS05605	COG0420	3'-5' exonuclease activity
LAZ97_RS05610	COG0419	ATPase involved in DNA repair
LAZ97_RS05615	COG1403	HNH endonuclease
LAZ97_RS05655	COG0179	Fumarylacetoacetate (FAA) hydrolase
LAZ97_RS05670	COG0367	asparagine synthase
LAZ97_RS05675	COG1562	ergosterol biosynthetic process
LAZ97_RS05680	COG0534	Mate efflux family protein
LAZ97_RS05685	COG1917	Cupin 2, conserved barrel domain protein
LAZ97_RS05685	COG2207	Transcriptional regulator
LAZ97_RS05690	COG1609	Transcriptional regulator
LAZ97_RS05695	COG0673	inositol 2-dehydrogenase activity
LAZ97_RS05700	COG2318	DinB family
LAZ97_RS05705	COG1279	arginine transmembrane transporter activity
LAZ97_RS05710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LAZ97_RS05715	COG1357	PFAM Pentapeptide repeats (8 copies)
LAZ97_RS05720	COG2153	protein acetylation
LAZ97_RS05725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LAZ97_RS05725	COG0646	methionine synthase
LAZ97_RS05735	COG2996	Protein conserved in bacteria
LAZ97_RS05740	COG1744	ABC transporter substrate-binding protein PnrA-like
LAZ97_RS05745	COG0840	transmembrane signaling receptor activity
LAZ97_RS05750	COG2124	cytochrome p450
LAZ97_RS05760	COG1307	EDD domain protein, DegV family
LAZ97_RS05765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAZ97_RS05785	COG0561	phosphatase activity
LAZ97_RS05790	COG1073	alpha beta
LAZ97_RS05795	COG2151	metal-sulfur cluster biosynthetic enzyme
LAZ97_RS05805	COG0277	FAD linked oxidase domain protein
LAZ97_RS05810	COG2271	Major facilitator Superfamily
LAZ97_RS05820	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LAZ97_RS05830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LAZ97_RS05835	COG0505	Belongs to the CarA family
LAZ97_RS05840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LAZ97_RS05845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LAZ97_RS05875	COG1744	ABC transporter substrate-binding protein PnrA-like
LAZ97_RS05890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LAZ97_RS05895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LAZ97_RS05900	COG5504	Zn-dependent protease
LAZ97_RS05905	COG0444	Belongs to the ABC transporter superfamily
LAZ97_RS05910	COG4608	Belongs to the ABC transporter superfamily
LAZ97_RS05920	COG0601	transmembrane transport
LAZ97_RS05925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LAZ97_RS05935	COG0180	Tryptophanyl-tRNA synthetase
LAZ97_RS05940	COG4166	transmembrane transport
LAZ97_RS05945	COG0601	transmembrane transport
LAZ97_RS05950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LAZ97_RS05955	COG0444	Belongs to the ABC transporter superfamily
LAZ97_RS05960	COG4608	Belongs to the ABC transporter superfamily
LAZ97_RS05970	COG0456	acetyltransferase
LAZ97_RS05975	COG1393	Belongs to the ArsC family
LAZ97_RS05980	COG0861	Integral membrane protein TerC family
LAZ97_RS05985	COG4862	establishment of competence for transformation
LAZ97_RS05990	COG4469	Competence protein
LAZ97_RS05995	COG1164	Oligoendopeptidase f
LAZ97_RS06005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LAZ97_RS06010	COG2346	COG2346, Truncated hemoglobins
LAZ97_RS06015	COG0741	lytic transglycosylase activity
LAZ97_RS06020	COG4116	CYTH
LAZ97_RS06030	COG2357	RelA SpoT domain protein
LAZ97_RS06035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LAZ97_RS06040	COG0564	pseudouridine synthase activity
LAZ97_RS06050	COG0569	domain protein
LAZ97_RS06050	COG0475	glutathione-regulated potassium exporter activity
LAZ97_RS06055	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LAZ97_RS06060	COG0352	thiamine-phosphate diphosphorylase activity
LAZ97_RS06065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LAZ97_RS06070	COG2104	thiamine diphosphate biosynthetic process
LAZ97_RS06080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LAZ97_RS06085	COG0351	phosphomethylpyrimidine kinase
LAZ97_RS06090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LAZ97_RS06145	COG0210	DNA helicase
LAZ97_RS06165	COG1131	(ABC) transporter
LAZ97_RS06175	COG2153	protein acetylation
LAZ97_RS06185	COG2382	esterase
LAZ97_RS06190	COG0626	cystathionine gamma-synthase activity
LAZ97_RS06195	COG0626	cystathionine gamma-synthase activity
LAZ97_RS06255	COG1484	DNA-dependent DNA replication
LAZ97_RS06280	COG3655	Transcriptional regulator
LAZ97_RS06320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LAZ97_RS06320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LAZ97_RS06360	COG1780	Probably involved in ribonucleotide reductase function
LAZ97_RS06365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LAZ97_RS06375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LAZ97_RS06385	COG0756	dUTP diphosphatase activity
LAZ97_RS06390	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
LAZ97_RS06395	COG3584	3D domain protein
LAZ97_RS06440	COG1793	dna ligase
LAZ97_RS06505	COG0582	viral genome integration into host DNA
LAZ97_RS06585	COG1705	Flagellar rod assembly protein muramidase FlgJ
LAZ97_RS06595	COG5434	Belongs to the glycosyl hydrolase 28 family
LAZ97_RS06615	COG4824	toxin secretion phage lysis holin
LAZ97_RS06620	COG5632	N-Acetylmuramoyl-L-alanine amidase
LAZ97_RS06620	COG3409	Peptidoglycan-binding domain 1 protein
LAZ97_RS06655	COG0582	viral genome integration into host DNA
LAZ97_RS06765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LAZ97_RS06825	COG3328	transposase activity
LAZ97_RS06895	COG5444	nuclease activity
LAZ97_RS06930	COG2367	Beta-lactamase
LAZ97_RS06935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LAZ97_RS06940	COG0477	Major facilitator Superfamily
LAZ97_RS06945	COG1846	Transcriptional regulator
LAZ97_RS06955	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LAZ97_RS06960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LAZ97_RS06965	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LAZ97_RS06970	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LAZ97_RS06970	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LAZ97_RS06975	COG1447	Phosphotransferase system cellobiose-specific component IIA
LAZ97_RS07005	COG1285	pathogenesis
LAZ97_RS07015	COG2205	protein histidine kinase activity
LAZ97_RS07025	COG3383	formate dehydrogenase (NAD+) activity
LAZ97_RS07030	COG2427	Protein of unknown function (DUF1641)
LAZ97_RS07035	COG2124	cytochrome p450
LAZ97_RS07050	COG1587	Uroporphyrinogen-III synthase
LAZ97_RS07055	COG0390	transport system, permease component
LAZ97_RS07060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LAZ97_RS07065	COG0697	spore germination
LAZ97_RS07070	COG4297	protein containing double-stranded beta helix domain
LAZ97_RS07080	COG1252	NADH dehydrogenase
LAZ97_RS07095	COG1609	Transcriptional regulator
LAZ97_RS07100	COG0246	Mannitol dehydrogenase
LAZ97_RS07105	COG2721	sulfolactate sulfo-lyase activity
LAZ97_RS07110	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS07115	COG2205	protein histidine kinase activity
LAZ97_RS07115	COG2770	Histidine kinase
LAZ97_RS07135	COG4585	Histidine kinase
LAZ97_RS07140	COG2197	response regulator
LAZ97_RS07180	COG0730	response to heat
LAZ97_RS07185	COG2318	DinB family
LAZ97_RS07190	COG0457	Tetratricopeptide repeat
LAZ97_RS07200	COG3409	Peptidoglycan-binding domain 1 protein
LAZ97_RS07200	COG1388	LysM domain
LAZ97_RS07200	COG5632	N-Acetylmuramoyl-L-alanine amidase
LAZ97_RS07210	COG4195	phage-related replication protein
LAZ97_RS07215	COG2856	Zn peptidase
LAZ97_RS07220	COG1396	sequence-specific DNA binding
LAZ97_RS07230	COG1522	sequence-specific DNA binding
LAZ97_RS07235	COG1484	DNA-dependent DNA replication
LAZ97_RS07255	COG1595	DNA-templated transcription, initiation
LAZ97_RS07295	COG3409	Peptidoglycan-binding domain 1 protein
LAZ97_RS07295	COG5632	N-Acetylmuramoyl-L-alanine amidase
LAZ97_RS07315	COG0306	phosphate transporter
LAZ97_RS07320	COG1392	Phosphate transport regulator
LAZ97_RS07325	COG0531	amino acid
LAZ97_RS07330	COG0346	lactoylglutathione lyase activity
LAZ97_RS07335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LAZ97_RS07340	COG0463	Glycosyl transferase, family 2
LAZ97_RS07350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LAZ97_RS07355	COG0477	Major facilitator Superfamily
LAZ97_RS07360	COG2362	D-Aminopeptidase
LAZ97_RS07365	COG0601	transmembrane transport
LAZ97_RS07370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LAZ97_RS07375	COG0444	Belongs to the ABC transporter superfamily
LAZ97_RS07380	COG4166	transmembrane transport
LAZ97_RS07385	COG1619	proteins homologs of microcin C7 resistance protein MccF
LAZ97_RS07390	COG4948	Mandelate Racemase Muconate Lactonizing
LAZ97_RS07395	COG0791	NLP P60 protein
LAZ97_RS07400	COG4608	Belongs to the ABC transporter superfamily
LAZ97_RS07405	COG2706	6-phosphogluconolactonase activity
LAZ97_RS07410	COG1834	amidinotransferase
LAZ97_RS07420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LAZ97_RS07425	COG2076	Multidrug Resistance protein
LAZ97_RS07430	COG2076	Multidrug Resistance protein
LAZ97_RS07435	COG0788	formyltetrahydrofolate deformylase activity
LAZ97_RS07440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LAZ97_RS07450	COG1764	response to oxidative stress
LAZ97_RS07455	COG1846	Transcriptional regulator
LAZ97_RS07460	COG1764	response to oxidative stress
LAZ97_RS07475	COG0463	Glycosyl transferase, family 2
LAZ97_RS07475	COG0457	Tetratricopeptide repeat
LAZ97_RS07485	COG2814	Major facilitator Superfamily
LAZ97_RS07490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LAZ97_RS07500	COG1404	Belongs to the peptidase S8 family
LAZ97_RS07505	COG1366	Belongs to the anti-sigma-factor antagonist family
LAZ97_RS07510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LAZ97_RS07515	COG1122	ATPase activity
LAZ97_RS07520	COG4721	ABC-type cobalt transport system, permease component
LAZ97_RS07525	COG3858	chitin binding
LAZ97_RS07525	COG1388	LysM domain
LAZ97_RS07535	COG2239	Acts as a magnesium transporter
LAZ97_RS07540	COG0789	Transcriptional regulator
LAZ97_RS07555	COG1846	Transcriptional regulator
LAZ97_RS07560	COG0726	polysaccharide deacetylase
LAZ97_RS07565	COG1793	dna ligase
LAZ97_RS07565	COG3285	dna ligase
LAZ97_RS07570	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LAZ97_RS07575	COG0586	Pfam SNARE associated Golgi protein
LAZ97_RS07585	COG1191	sigma factor activity
LAZ97_RS07610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LAZ97_RS07615	COG2323	membrane
LAZ97_RS07625	COG3594	Acyltransferase
LAZ97_RS07630	COG5002	protein histidine kinase activity
LAZ97_RS07635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LAZ97_RS07655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LAZ97_RS07660	COG0436	Aminotransferase
LAZ97_RS07690	COG3852	Histidine kinase
LAZ97_RS07695	COG1846	Transcriptional regulator
LAZ97_RS07700	COG1360	Flagellar Motor Protein
LAZ97_RS07705	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LAZ97_RS07710	COG0542	response to heat
LAZ97_RS07715	COG3949	Membrane
LAZ97_RS07730	COG0720	synthase
LAZ97_RS07735	COG0602	queuosine metabolic process
LAZ97_RS07740	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LAZ97_RS07745	COG1733	regulation of RNA biosynthetic process
LAZ97_RS07750	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS07770	COG4873	Protein conserved in bacteria
LAZ97_RS07780	COG3773	Cell wall hydrolase
LAZ97_RS07785	COG2244	polysaccharide biosynthetic process
LAZ97_RS07790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LAZ97_RS07795	COG2217	Heavy metal translocating P-type atpase
LAZ97_RS07800	COG0006	proline dipeptidase activity
LAZ97_RS07805	COG1609	Transcriptional regulator
LAZ97_RS07810	COG3711	transcriptional antiterminator
LAZ97_RS07815	COG1263	PTS System
LAZ97_RS07815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LAZ97_RS07815	COG2190	(PTS) system
LAZ97_RS07820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LAZ97_RS07825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LAZ97_RS07835	COG1533	DNA photolyase activity
LAZ97_RS07840	COG0840	transmembrane signaling receptor activity
LAZ97_RS07845	COG2084	Dehydrogenase
LAZ97_RS07850	COG2340	Cysteine-rich secretory protein family
LAZ97_RS07855	COG0768	penicillin binding
LAZ97_RS07860	COG4191	Histidine kinase
LAZ97_RS07865	COG0436	Aminotransferase
LAZ97_RS07875	COG0835	chemotaxis
LAZ97_RS07875	COG0784	Response regulator, receiver
LAZ97_RS07885	COG2814	Major facilitator Superfamily
LAZ97_RS07890	COG1376	ErfK ybiS ycfS ynhG family protein
LAZ97_RS07895	COG1408	metallophosphoesterase
LAZ97_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS07910	COG2200	EAL domain
LAZ97_RS07915	COG4703	Protein of unknown function (DUF1797)
LAZ97_RS07920	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LAZ97_RS07930	COG0517	IMP dehydrogenase activity
LAZ97_RS07935	COG0583	DNA-binding transcription factor activity
LAZ97_RS07940	COG0716	FMN binding
LAZ97_RS07950	COG0716	FMN binding
LAZ97_RS07970	COG0668	transmembrane transport
LAZ97_RS07975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LAZ97_RS07995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LAZ97_RS08000	COG0303	'Molybdopterin
LAZ97_RS08005	COG1763	Mo-molybdopterin cofactor biosynthetic process
LAZ97_RS08010	COG0314	molybdopterin synthase activity
LAZ97_RS08015	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LAZ97_RS08025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LAZ97_RS08030	COG1136	(ABC) transporter
LAZ97_RS08035	COG0577	efflux transmembrane transporter activity
LAZ97_RS08040	COG1349	DNA-binding transcription factor activity
LAZ97_RS08045	COG1105	Belongs to the carbohydrate kinase PfkB family
LAZ97_RS08050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LAZ97_RS08050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LAZ97_RS08050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LAZ97_RS08055	COG0681	Belongs to the peptidase S26 family
LAZ97_RS08065	COG0488	(ABC) transporter
LAZ97_RS08070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LAZ97_RS08075	COG2309	aminopeptidase activity
LAZ97_RS08085	COG1077	Cell shape determining protein MreB Mrl
LAZ97_RS08090	COG2002	toxin-antitoxin pair type II binding
LAZ97_RS08095	COG3852	Histidine kinase
LAZ97_RS08100	COG2105	PFAM AIG2 family protein
LAZ97_RS08100	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LAZ97_RS08105	COG0569	domain protein
LAZ97_RS08115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LAZ97_RS08125	COG0561	phosphatase activity
LAZ97_RS08130	COG0242	peptide deformylase activity
LAZ97_RS08140	COG0497	DNA recombination
LAZ97_RS08150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS08150	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS08150	COG3321	synthase
LAZ97_RS08150	COG4221	oxidoreductase activity
LAZ97_RS08155	COG4221	oxidoreductase activity
LAZ97_RS08155	COG3321	synthase
LAZ97_RS08155	COG0300	oxidoreductase activity
LAZ97_RS08155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS08160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS08160	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS08160	COG4221	oxidoreductase activity
LAZ97_RS08160	COG3321	synthase
LAZ97_RS08165	COG3321	synthase
LAZ97_RS08165	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS08165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS08165	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS08165	COG0300	oxidoreductase activity
LAZ97_RS08170	COG3321	synthase
LAZ97_RS08170	COG0300	oxidoreductase activity
LAZ97_RS08170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS08170	COG4221	oxidoreductase activity
LAZ97_RS08175	COG0300	oxidoreductase activity
LAZ97_RS08175	COG3321	synthase
LAZ97_RS08175	COG4221	oxidoreductase activity
LAZ97_RS08175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS08180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS08180	COG3321	synthase
LAZ97_RS08180	COG4221	oxidoreductase activity
LAZ97_RS08185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LAZ97_RS08190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LAZ97_RS08195	COG0022	dehydrogenase e1 component
LAZ97_RS08200	COG0508	dehydrogenase complex catalyzes the overall conversion of
LAZ97_RS08205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LAZ97_RS08210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LAZ97_RS08225	COG1982	Orn Lys Arg decarboxylase major
LAZ97_RS08245	COG0483	inositol monophosphate 1-phosphatase activity
LAZ97_RS08255	COG3227	Zinc metalloprotease (Elastase)
LAZ97_RS08270	COG1595	DNA-templated transcription, initiation
LAZ97_RS08290	COG1217	gtp-binding protein TYPA
LAZ97_RS08300	COG4896	Protein conserved in bacteria
LAZ97_RS08310	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LAZ97_RS08315	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LAZ97_RS08320	COG2066	Belongs to the glutaminase family
LAZ97_RS08330	COG0772	Belongs to the SEDS family
LAZ97_RS08335	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LAZ97_RS08350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LAZ97_RS08350	COG2010	Cytochrome c
LAZ97_RS08355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LAZ97_RS08360	COG1845	cytochrome c oxidase, subunit III
LAZ97_RS08365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LAZ97_RS08370	COG3336	cytochrome c oxidase
LAZ97_RS08380	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LAZ97_RS08385	COG2340	Cysteine-rich secretory protein family
LAZ97_RS08400	COG3679	Belongs to the UPF0342 family
LAZ97_RS08410	COG0742	ribosomal rna small subunit methyltransferase
LAZ97_RS08420	COG3314	Sporulation integral membrane protein YlbJ
LAZ97_RS08425	COG1752	Esterase of the alpha-beta hydrolase superfamily
LAZ97_RS08430	COG3480	Lon protease (S16) C-terminal proteolytic domain
LAZ97_RS08440	COG1399	metal-binding, possibly nucleic acid-binding protein
LAZ97_RS08460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LAZ97_RS08480	COG4839	cell division protein FtsL
LAZ97_RS08485	COG0768	penicillin binding
LAZ97_RS08490	COG0768	penicillin binding
LAZ97_RS08510	COG0772	Belongs to the SEDS family
LAZ97_RS08525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LAZ97_RS08530	COG0849	cell division
LAZ97_RS08535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LAZ97_RS08540	COG1404	Belongs to the peptidase S8 family
LAZ97_RS08540	COG4412	M6 family metalloprotease domain protein
LAZ97_RS08550	COG1191	sigma factor activity
LAZ97_RS08555	COG1191	sigma factor activity
LAZ97_RS08560	COG1119	ATPase activity
LAZ97_RS08565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LAZ97_RS08570	COG1873	PFAM PRC-barrel domain
LAZ97_RS08575	COG1496	oxidoreductase activity
LAZ97_RS08580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LAZ97_RS08590	COG0762	integral membrane protein
LAZ97_RS08595	COG2302	S4 RNA-binding domain
LAZ97_RS08600	COG3599	regulation of cell shape
LAZ97_RS08605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LAZ97_RS08610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LAZ97_RS08620	COG0564	pseudouridine synthase activity
LAZ97_RS08630	COG2233	PERMEase
LAZ97_RS08640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LAZ97_RS08645	COG0505	Belongs to the CarA family
LAZ97_RS08650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LAZ97_RS08665	COG0284	orotidine-5'-phosphate decarboxylase activity
LAZ97_RS08670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LAZ97_RS08680	COG0306	phosphate transporter
LAZ97_RS08695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LAZ97_RS08700	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LAZ97_RS08705	COG1648	precorrin-2 dehydrogenase activity
LAZ97_RS08720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LAZ97_RS08725	COG1561	YicC-like family, N-terminal region
LAZ97_RS08735	COG0194	GDP metabolic process
LAZ97_RS08745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LAZ97_RS08750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LAZ97_RS08755	COG0242	peptide deformylase activity
LAZ97_RS08765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LAZ97_RS08765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LAZ97_RS08775	COG0631	protein serine/threonine phosphatase activity
LAZ97_RS08780	COG0515	serine threonine protein kinase
LAZ97_RS08780	COG2815	serine threonine protein kinase
LAZ97_RS08790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LAZ97_RS08795	COG1564	THIamine pyrophosphokinase
LAZ97_RS08810	COG1302	Protein conserved in bacteria
LAZ97_RS08815	COG1461	Dihydroxyacetone kinase
LAZ97_RS08820	COG1760	l-serine dehydratase
LAZ97_RS08825	COG1760	l-serine dehydratase
LAZ97_RS08830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LAZ97_RS08845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LAZ97_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS08865	COG1196	nuclear chromosome segregation
LAZ97_RS08870	COG0552	protein localization to endoplasmic reticulum
LAZ97_RS08885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LAZ97_RS08895	COG1837	Belongs to the UPF0109 family
LAZ97_RS08920	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LAZ97_RS08935	COG2257	FlhB HrpN YscU SpaS Family
LAZ97_RS08945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LAZ97_RS08950	COG0758	DNA mediated transformation
LAZ97_RS08955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LAZ97_RS08965	COG4974	Belongs to the 'phage' integrase family
LAZ97_RS08985	COG1815	bacterial-type flagellum-dependent cell motility
LAZ97_RS08990	COG1558	bacterial-type flagellum-dependent cell motility
LAZ97_RS08995	COG1677	Flagellar hook-basal body complex protein FliE
LAZ97_RS09000	COG1766	The M ring may be actively involved in energy transduction
LAZ97_RS09005	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LAZ97_RS09010	COG1317	bacterial-type flagellum organization
LAZ97_RS09015	COG1157	protein secretion by the type III secretion system
LAZ97_RS09020	COG2882	bacterial-type flagellum organization
LAZ97_RS09025	COG3334	PFAM MgtE intracellular
LAZ97_RS09030	COG3144	bacterial-type flagellum assembly
LAZ97_RS09035	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LAZ97_RS09040	COG4786	Flagellar basal body rod
LAZ97_RS09045	COG1582	Flagellar protein (FlbD)
LAZ97_RS09050	COG1580	Controls the rotational direction of flagella during chemotaxis
LAZ97_RS09055	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LAZ97_RS09060	COG1776	CheC inhibitor of MCP methylation
LAZ97_RS09060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LAZ97_RS09065	COG2201	protein-glutamate methylesterase activity
LAZ97_RS09070	COG3190	flagellar
LAZ97_RS09075	COG1338	Plays a role in the flagellum-specific transport system
LAZ97_RS09080	COG1987	bacterial-type flagellum assembly
LAZ97_RS09085	COG1684	flagellar biosynthetic protein fliR
LAZ97_RS09090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LAZ97_RS09095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LAZ97_RS09100	COG1419	protein localization to endoplasmic reticulum
LAZ97_RS09105	COG0455	bacterial-type flagellum organization
LAZ97_RS09110	COG2201	protein-glutamate methylesterase activity
LAZ97_RS09115	COG2198	Histidine kinase
LAZ97_RS09115	COG0643	Histidine kinase
LAZ97_RS09120	COG0835	chemotaxis
LAZ97_RS09125	COG1776	CheC inhibitor of MCP methylation
LAZ97_RS09135	COG1191	sigma factor activity
LAZ97_RS09165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LAZ97_RS09170	COG4589	Belongs to the CDS family
LAZ97_RS09180	COG0750	zinc metalloprotease
LAZ97_RS09200	COG0195	Participates in both transcription termination and antitermination
LAZ97_RS09205	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LAZ97_RS09210	COG1358	cellular component organization or biogenesis
LAZ97_RS09220	COG1550	Protein conserved in bacteria
LAZ97_RS09235	COG0196	riboflavin kinase activity
LAZ97_RS09250	COG0726	polysaccharide deacetylase
LAZ97_RS09255	COG0612	Peptidase, M16
LAZ97_RS09260	COG1873	PFAM PRC-barrel domain
LAZ97_RS09265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAZ97_RS09270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LAZ97_RS09275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LAZ97_RS09280	COG0527	aspartate kinase activity
LAZ97_RS09290	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LAZ97_RS09295	COG0740	serine-type endopeptidase activity
LAZ97_RS09305	COG4980	gas vesicle protein
LAZ97_RS09305	COG1674	ftsk spoiiie
LAZ97_RS09310	COG2188	Transcriptional regulator
LAZ97_RS09315	COG2814	Major facilitator Superfamily
LAZ97_RS09320	COG1846	Transcriptional regulator
LAZ97_RS09325	COG1033	growth of symbiont in host cell
LAZ97_RS09325	COG2409	Drug exporters of the RND superfamily
LAZ97_RS09330	COG0612	Peptidase, M16
LAZ97_RS09335	COG0612	Peptidase, M16
LAZ97_RS09340	COG0300	oxidoreductase activity
LAZ97_RS09355	COG1426	Protein conserved in bacteria
LAZ97_RS09360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LAZ97_RS09375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LAZ97_RS09385	COG1692	metallophosphoesterase
LAZ97_RS09390	COG2359	stage V sporulation protein S
LAZ97_RS09410	COG4550	Control of competence regulator ComK, YlbF/YmcA
LAZ97_RS09470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS09475	COG3425	synthase
LAZ97_RS09480	COG1024	Enoyl-CoA hydratase
LAZ97_RS09485	COG1024	Enoyl-CoA hydratase
LAZ97_RS09510	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LAZ97_RS09510	COG3321	synthase
LAZ97_RS09510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LAZ97_RS09510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS09515	COG2124	cytochrome p450
LAZ97_RS09520	COG3209	COG3209 Rhs family protein
LAZ97_RS09565	COG2124	cytochrome p450
LAZ97_RS09575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS09575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LAZ97_RS09575	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LAZ97_RS09575	COG3321	synthase
LAZ97_RS09580	COG2124	cytochrome p450
LAZ97_RS09585	COG3209	COG3209 Rhs family protein
LAZ97_RS09590	COG3619	membrane
LAZ97_RS09600	COG1404	Belongs to the peptidase S8 family
LAZ97_RS09610	COG4195	phage-related replication protein
LAZ97_RS09615	COG1764	response to oxidative stress
LAZ97_RS09625	COG2076	Multidrug Resistance protein
LAZ97_RS09665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LAZ97_RS09670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LAZ97_RS09675	COG4112	unkown
LAZ97_RS09680	COG0860	N-Acetylmuramoyl-L-alanine amidase
LAZ97_RS09685	COG0464	growth
LAZ97_RS09690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LAZ97_RS09695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LAZ97_RS09700	COG0789	Transcriptional regulator
LAZ97_RS09705	COG0174	glutamine synthetase
LAZ97_RS09725	COG2211	Major facilitator Superfamily
LAZ97_RS09730	COG3507	Belongs to the glycosyl hydrolase 43 family
LAZ97_RS09745	COG1070	Carbohydrate kinase
LAZ97_RS09750	COG0574	Belongs to the PEP-utilizing enzyme family
LAZ97_RS09750	COG3848	Pyruvate phosphate dikinase
LAZ97_RS09770	COG2378	regulation of single-species biofilm formation
LAZ97_RS09775	COG2318	DinB family
LAZ97_RS09780	COG1064	alcohol dehydrogenase
LAZ97_RS09805	COG0456	acetyltransferase
LAZ97_RS09810	COG5444	nuclease activity
LAZ97_RS09865	COG3397	chitin binding
LAZ97_RS09885	COG5434	Belongs to the glycosyl hydrolase 28 family
LAZ97_RS09890	COG0756	dUTP diphosphatase activity
LAZ97_RS09895	COG4195	phage-related replication protein
LAZ97_RS09930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LAZ97_RS09940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LAZ97_RS09960	COG0785	Cytochrome C biogenesis protein
LAZ97_RS09965	COG2201	protein-glutamate methylesterase activity
LAZ97_RS09970	COG4846	Membrane protein involved in cytochrome C biogenesis
LAZ97_RS09980	COG0071	Belongs to the small heat shock protein (HSP20) family
LAZ97_RS09995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LAZ97_RS10000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LAZ97_RS10020	COG0824	Thioesterase
LAZ97_RS10030	COG4841	protein insertion into membrane
LAZ97_RS10040	COG1832	CoA-binding protein
LAZ97_RS10045	COG0187	DNA topoisomerase II activity
LAZ97_RS10050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LAZ97_RS10060	COG1115	amino acid carrier protein
LAZ97_RS10070	COG1063	alcohol dehydrogenase
LAZ97_RS10075	COG0800	Aldolase
LAZ97_RS10080	COG1312	Catalyzes the dehydration of D-mannonate
LAZ97_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS10090	COG1609	Transcriptional regulator
LAZ97_RS10095	COG2271	Major facilitator Superfamily
LAZ97_RS10140	COG2205	protein histidine kinase activity
LAZ97_RS10145	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS10155	COG3507	Belongs to the glycosyl hydrolase 43 family
LAZ97_RS10180	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS10185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LAZ97_RS10190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LAZ97_RS10195	COG2610	gluconate transmembrane transporter activity
LAZ97_RS10200	COG2124	cytochrome p450
LAZ97_RS10220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LAZ97_RS10230	COG2246	polysaccharide biosynthetic process
LAZ97_RS10235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LAZ97_RS10240	COG0586	Pfam SNARE associated Golgi protein
LAZ97_RS10245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LAZ97_RS10250	COG1024	Enoyl-CoA hydratase
LAZ97_RS10255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LAZ97_RS10260	COG0511	ligase activity, forming carbon-carbon bonds
LAZ97_RS10265	COG0439	Biotin carboxylase
LAZ97_RS10270	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS10275	COG1960	acyl-CoA dehydrogenase activity
LAZ97_RS10280	COG1649	PFAM Uncharacterised BCR, COG1649
LAZ97_RS10290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS10290	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LAZ97_RS10305	COG2323	membrane
LAZ97_RS10310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LAZ97_RS10320	COG2323	membrane
LAZ97_RS10335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LAZ97_RS10380	COG2027	D-alanyl-D-alanine carboxypeptidase
LAZ97_RS10385	COG2017	converts alpha-aldose to the beta-anomer
LAZ97_RS10390	COG0534	Mate efflux family protein
LAZ97_RS10405	COG0582	viral genome integration into host DNA
LAZ97_RS10410	COG0166	Belongs to the GPI family
LAZ97_RS10415	COG0405	Gamma-glutamyltransferase
LAZ97_RS10420	COG2814	Major facilitator Superfamily
LAZ97_RS10425	COG0640	Transcriptional regulator
LAZ97_RS10430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LAZ97_RS10440	COG0604	alcohol dehydrogenase
LAZ97_RS10450	COG0493	'glutamate synthase
LAZ97_RS10455	COG0070	glutamate synthase
LAZ97_RS10455	COG0067	glutamate synthase
LAZ97_RS10455	COG0069	glutamate synthase activity
LAZ97_RS10460	COG0583	DNA-binding transcription factor activity
LAZ97_RS10465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LAZ97_RS10480	COG0300	oxidoreductase activity
LAZ97_RS10485	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LAZ97_RS10495	COG2814	Major facilitator Superfamily
LAZ97_RS10500	COG1070	Carbohydrate kinase
LAZ97_RS10510	COG0243	molybdopterin cofactor binding
LAZ97_RS10540	COG5444	nuclease activity
LAZ97_RS10545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LAZ97_RS10550	COG0662	Cupin 2, conserved barrel domain protein
LAZ97_RS10550	COG2207	Transcriptional regulator
LAZ97_RS10555	COG1309	transcriptional regulator
LAZ97_RS10560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LAZ97_RS10570	COG0640	Transcriptional regulator
LAZ97_RS10575	COG0741	lytic transglycosylase activity
LAZ97_RS10580	COG2322	membrane
LAZ97_RS10595	COG1619	proteins homologs of microcin C7 resistance protein MccF
LAZ97_RS10605	COG3584	3D domain protein
LAZ97_RS10605	COG1388	LysM domain
LAZ97_RS10610	COG0514	ATP-dependent DNA helicase (RecQ)
LAZ97_RS10620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LAZ97_RS10625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LAZ97_RS10640	COG0071	Belongs to the small heat shock protein (HSP20) family
LAZ97_RS10670	COG1012	belongs to the aldehyde dehydrogenase family
LAZ97_RS10675	COG1657	PFAM Prenyltransferase squalene oxidase
LAZ97_RS10680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LAZ97_RS10685	COG0733	neurotransmitter:sodium symporter activity
LAZ97_RS10690	COG0385	Bile acid
LAZ97_RS10695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LAZ97_RS10700	COG0508	dehydrogenase complex catalyzes the overall conversion of
LAZ97_RS10710	COG4548	von Willebrand factor, type A
LAZ97_RS10715	COG0714	Associated with various cellular activities
LAZ97_RS10720	COG2032	superoxide dismutase activity
LAZ97_RS10725	COG0791	NLP P60 protein
LAZ97_RS10725	COG1388	LysM domain
LAZ97_RS10730	COG1819	glycosyl
LAZ97_RS10735	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LAZ97_RS10740	COG0534	Mate efflux family protein
LAZ97_RS10745	COG1366	Belongs to the anti-sigma-factor antagonist family
LAZ97_RS10750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LAZ97_RS10755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LAZ97_RS10765	COG2962	Rard protein
LAZ97_RS10780	COG1942	4-Oxalocrotonate Tautomerase
LAZ97_RS10790	COG1733	regulation of RNA biosynthetic process
LAZ97_RS10795	COG0778	Nitroreductase
LAZ97_RS10800	COG0400	carboxylic ester hydrolase activity
LAZ97_RS10805	COG0346	lactoylglutathione lyase activity
LAZ97_RS10815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LAZ97_RS10825	COG2723	6-phospho-beta-galactosidase activity
LAZ97_RS10830	COG2188	Transcriptional regulator
LAZ97_RS10835	COG0793	Belongs to the peptidase S41A family
LAZ97_RS10835	COG3409	Peptidoglycan-binding domain 1 protein
LAZ97_RS10840	COG2226	methyltransferase
LAZ97_RS10850	COG1876	peptidase activity
LAZ97_RS10870	COG0671	phosphoesterase, PA-phosphatase related
LAZ97_RS10905	COG1509	lysine 2,3-aminomutase activity
LAZ97_RS10910	COG0456	acetyltransferase
LAZ97_RS10915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LAZ97_RS10920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LAZ97_RS10925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LAZ97_RS10930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LAZ97_RS10945	COG0456	acetyltransferase
LAZ97_RS10950	COG0463	Glycosyl transferase, family 2
LAZ97_RS10965	COG4641	Protein conserved in bacteria
LAZ97_RS10975	COG1086	Polysaccharide biosynthesis protein
LAZ97_RS10990	COG1846	Transcriptional regulator
LAZ97_RS10995	COG4698	Protein conserved in bacteria
LAZ97_RS11000	COG2755	lipolytic protein G-D-S-L family
LAZ97_RS11005	COG1999	signal sequence binding
LAZ97_RS11015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LAZ97_RS11020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LAZ97_RS11025	COG1272	protein, Hemolysin III
LAZ97_RS11030	COG0204	Acyl-transferase
LAZ97_RS11035	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LAZ97_RS11050	COG2521	methyltransferase
LAZ97_RS11050	COG2136	Putative SAM-dependent methyltransferase
LAZ97_RS11065	COG1413	lyase activity
LAZ97_RS11070	COG1418	mRNA catabolic process
LAZ97_RS11075	COG0386	Belongs to the glutathione peroxidase family
LAZ97_RS11085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LAZ97_RS11095	COG1278	Cold shock
LAZ97_RS11115	COG0328	RNA-DNA hybrid ribonuclease activity
LAZ97_RS11120	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LAZ97_RS11125	COG0328	RNA-DNA hybrid ribonuclease activity
LAZ97_RS11135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LAZ97_RS11150	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LAZ97_RS11170	COG1335	isochorismatase
LAZ97_RS11175	COG2233	PERMEase
LAZ97_RS11185	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LAZ97_RS11190	COG1199	ATP-dependent helicase activity
LAZ97_RS11205	COG0116	Belongs to the methyltransferase superfamily
LAZ97_RS11235	COG3359	exonuclease
LAZ97_RS11240	COG1111	helicase
LAZ97_RS11240	COG1205	dead DEAH box helicase
LAZ97_RS11245	COG2190	(PTS) system
LAZ97_RS11250	COG0071	Belongs to the small heat shock protein (HSP20) family
LAZ97_RS11290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LAZ97_RS11290	COG4499	WXG100 protein secretion system (Wss), protein YukC
LAZ97_RS11300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LAZ97_RS11305	COG3935	DnaD domain protein
LAZ97_RS11315	COG0436	Aminotransferase
LAZ97_RS11320	COG5353	protein conserved in bacteria
LAZ97_RS11330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LAZ97_RS11330	COG1199	ATP-dependent helicase activity
LAZ97_RS11360	COG0438	transferase activity, transferring glycosyl groups
LAZ97_RS11365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LAZ97_RS11380	COG1694	Mazg nucleotide pyrophosphohydrolase
LAZ97_RS11385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAZ97_RS11390	COG2140	Oxalate decarboxylase
LAZ97_RS11400	COG4347	Protein of unknown function (DUF1405)
LAZ97_RS11405	COG2010	Cytochrome c
LAZ97_RS11405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LAZ97_RS11410	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LAZ97_RS11415	COG0723	plastoquinol--plastocyanin reductase activity
LAZ97_RS11430	COG0457	Tetratricopeptide repeat
LAZ97_RS11440	COG0287	Prephenate dehydrogenase
LAZ97_RS11475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LAZ97_RS11480	COG4401	Chorismate mutase type I
LAZ97_RS11495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LAZ97_RS11500	COG0105	UTP biosynthetic process
LAZ97_RS11505	COG0142	geranyltranstransferase activity
LAZ97_RS11515	COG0142	geranyltranstransferase activity
LAZ97_RS11530	COG0776	regulation of translation
LAZ97_RS11535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LAZ97_RS11575	COG0539	negative regulation of cytoplasmic translation
LAZ97_RS11590	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LAZ97_RS11595	COG2959	enzyme of heme biosynthesis
LAZ97_RS11600	COG3773	Cell wall hydrolase
LAZ97_RS11600	COG3409	Peptidoglycan-binding domain 1 protein
LAZ97_RS11605	COG2339	peptidase activity
LAZ97_RS11610	COG0492	ferredoxin-NADP+ reductase activity
LAZ97_RS11615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LAZ97_RS11620	COG4862	establishment of competence for transformation
LAZ97_RS11625	COG1408	metallophosphoesterase
LAZ97_RS11635	COG1388	LysM domain
LAZ97_RS11640	COG1266	CAAX protease self-immunity
LAZ97_RS11645	COG0514	ATP-dependent DNA helicase (RecQ)
LAZ97_RS11650	COG4955	Helix-turn-helix domain
LAZ97_RS11655	COG1141	Ferredoxin
LAZ97_RS11660	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LAZ97_RS11665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LAZ97_RS11675	COG1595	DNA-templated transcription, initiation
LAZ97_RS11680	COG5002	protein histidine kinase activity
LAZ97_RS11685	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS11690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LAZ97_RS11695	COG1333	cytochrome c biogenesis protein
LAZ97_RS11700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LAZ97_RS11705	COG1187	pseudouridine synthase activity
LAZ97_RS11710	COG0700	Nucleoside recognition
LAZ97_RS11715	COG2715	membrane protein required for spore maturation
LAZ97_RS11720	COG1686	Belongs to the peptidase S11 family
LAZ97_RS11745	COG1547	Domain of unknown function (DUF309)
LAZ97_RS11750	COG0456	acetyltransferase
LAZ97_RS11765	COG0307	riboflavin synthase, alpha
LAZ97_RS11770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LAZ97_RS11770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LAZ97_RS11780	COG0681	Belongs to the peptidase S26 family
LAZ97_RS11790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LAZ97_RS11795	COG4086	secreted protein
LAZ97_RS11800	COG0019	diaminopimelate decarboxylase activity
LAZ97_RS11805	COG0697	spore germination
LAZ97_RS11820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LAZ97_RS11840	COG1191	sigma factor activity
LAZ97_RS11850	COG1366	Belongs to the anti-sigma-factor antagonist family
LAZ97_RS11855	COG1686	Belongs to the peptidase S11 family
LAZ97_RS11860	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LAZ97_RS11865	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LAZ97_RS11870	COG4974	Belongs to the 'phage' integrase family
LAZ97_RS11880	COG0735	belongs to the Fur family
LAZ97_RS11885	COG1300	Membrane
LAZ97_RS11900	COG0281	malic enzyme
LAZ97_RS11905	COG1757	Na H antiporter
LAZ97_RS11910	COG1027	Aspartate ammonia-lyase
LAZ97_RS11915	COG0252	asparaginase activity
LAZ97_RS11920	COG1396	sequence-specific DNA binding
LAZ97_RS11925	COG1379	DNA repair
LAZ97_RS11930	COG0494	nUDIX hydrolase
LAZ97_RS11940	COG0667	Aldo Keto reductase
LAZ97_RS11950	COG1073	alpha beta
LAZ97_RS11960	COG4918	Iron-sulphur cluster biosynthesis
LAZ97_RS11965	COG0456	acetyltransferase
LAZ97_RS11965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LAZ97_RS11970	COG2329	Antibiotic biosynthesis monooxygenase
LAZ97_RS11975	COG0456	acetyltransferase
LAZ97_RS11980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LAZ97_RS11995	COG0628	permease
LAZ97_RS12005	COG0346	lactoylglutathione lyase activity
LAZ97_RS12015	COG3048	D-serine ammonia-lyase activity
LAZ97_RS12020	COG0300	oxidoreductase activity
LAZ97_RS12025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LAZ97_RS12030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LAZ97_RS12035	COG1024	Enoyl-CoA hydratase
LAZ97_RS12040	COG3425	synthase
LAZ97_RS12045	COG2124	cytochrome p450
LAZ97_RS12050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS12050	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS12050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LAZ97_RS12050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS12050	COG3321	synthase
LAZ97_RS12055	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS12055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS12055	COG3321	synthase
LAZ97_RS12055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS12055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LAZ97_RS12060	COG3321	synthase
LAZ97_RS12060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS12060	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS12060	COG0300	oxidoreductase activity
LAZ97_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS12065	COG0300	oxidoreductase activity
LAZ97_RS12065	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS12065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS12065	COG3321	synthase
LAZ97_RS12065	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS12070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS12070	COG3321	synthase
LAZ97_RS12070	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS12070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS12070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LAZ97_RS12075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS12075	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS12075	COG3321	synthase
LAZ97_RS12075	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS12075	COG0300	oxidoreductase activity
LAZ97_RS12080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAZ97_RS12080	COG3321	synthase
LAZ97_RS12080	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS12080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS12080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LAZ97_RS12085	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS12090	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS12105	COG2070	2-Nitropropane dioxygenase
LAZ97_RS12105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LAZ97_RS12110	COG0250	Participates in transcription elongation, termination and antitermination
LAZ97_RS12135	COG0596	Alpha beta hydrolase
LAZ97_RS12150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LAZ97_RS12155	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LAZ97_RS12170	COG0706	membrane insertase activity
LAZ97_RS12175	COG2195	Cleaves the N-terminal amino acid of tripeptides
LAZ97_RS12180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LAZ97_RS12185	COG0346	lactoylglutathione lyase activity
LAZ97_RS12195	COG1376	ErfK ybiS ycfS ynhG family protein
LAZ97_RS12200	COG4129	membrane
LAZ97_RS12205	COG1126	abc transporter atp-binding protein
LAZ97_RS12210	COG0765	amino acid transport
LAZ97_RS12215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LAZ97_RS12225	COG1597	lipid kinase activity
LAZ97_RS12230	COG0508	dehydrogenase complex catalyzes the overall conversion of
LAZ97_RS12235	COG0022	dehydrogenase e1 component
LAZ97_RS12240	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LAZ97_RS12245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LAZ97_RS12250	COG3426	butyrate kinase activity
LAZ97_RS12255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LAZ97_RS12260	COG0280	phosphate acetyltransferase
LAZ97_RS12265	COG3290	protein histidine kinase activity
LAZ97_RS12265	COG3829	transcription factor binding
LAZ97_RS12275	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LAZ97_RS12280	COG2079	MmgE PrpD family protein
LAZ97_RS12285	COG0372	Belongs to the citrate synthase family
LAZ97_RS12290	COG1960	acyl-CoA dehydrogenase activity
LAZ97_RS12295	COG1250	3-hydroxyacyl-CoA dehydrogenase
LAZ97_RS12300	COG0183	Belongs to the thiolase family
LAZ97_RS12305	COG0584	glycerophosphoryl diester phosphodiesterase
LAZ97_RS12310	COG0860	N-Acetylmuramoyl-L-alanine amidase
LAZ97_RS12335	COG1902	pentaerythritol trinitrate reductase activity
LAZ97_RS12350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LAZ97_RS12355	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS12360	COG0750	zinc metalloprotease
LAZ97_RS12365	COG0497	DNA recombination
LAZ97_RS12375	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LAZ97_RS12385	COG0142	geranyltranstransferase activity
LAZ97_RS12395	COG1570	exodeoxyribonuclease VII activity
LAZ97_RS12410	COG1302	Protein conserved in bacteria
LAZ97_RS12415	COG0439	Biotin carboxylase
LAZ97_RS12420	COG0511	ligase activity, forming carbon-carbon bonds
LAZ97_RS12460	COG3854	ATPases associated with a variety of cellular activities
LAZ97_RS12475	COG0006	proline dipeptidase activity
LAZ97_RS12485	COG3872	metal-dependent enzyme
LAZ97_RS12495	COG1752	Esterase of the alpha-beta hydrolase superfamily
LAZ97_RS12510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LAZ97_RS12530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LAZ97_RS12545	COG1396	sequence-specific DNA binding
LAZ97_RS12555	COG0681	Belongs to the peptidase S26 family
LAZ97_RS12580	COG4940	Competence protein ComGF
LAZ97_RS12590	COG4970	Tfp pilus assembly protein FimT
LAZ97_RS12595	COG4537	Required for transformation and DNA binding
LAZ97_RS12600	COG1459	type II secretion system
LAZ97_RS12605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LAZ97_RS12615	COG1253	flavin adenine dinucleotide binding
LAZ97_RS12620	COG1366	Belongs to the anti-sigma-factor antagonist family
LAZ97_RS12630	COG1393	Belongs to the ArsC family
LAZ97_RS12640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LAZ97_RS12650	COG0011	TIGRFAM Protein of
LAZ97_RS12660	COG2866	Carboxypeptidase
LAZ97_RS12665	COG1940	carbohydrate kinase activity
LAZ97_RS12670	COG4483	Protein conserved in bacteria
LAZ97_RS12675	COG1757	Na H antiporter
LAZ97_RS12685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LAZ97_RS12700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LAZ97_RS12705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LAZ97_RS12710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LAZ97_RS12715	COG0581	inorganic phosphate transmembrane transporter activity
LAZ97_RS12720	COG0573	inorganic phosphate transmembrane transporter activity
LAZ97_RS12725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LAZ97_RS12730	COG0768	penicillin binding
LAZ97_RS12735	COG0477	Major facilitator Superfamily
LAZ97_RS12740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LAZ97_RS12745	COG2839	Protein conserved in bacteria
LAZ97_RS12750	COG5521	maltodextrose utilization protein MalA
LAZ97_RS12755	COG1388	LysM domain
LAZ97_RS12765	COG4709	membrane
LAZ97_RS12770	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LAZ97_RS12775	COG0735	belongs to the Fur family
LAZ97_RS12780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAZ97_RS12795	COG0513	Belongs to the DEAD box helicase family
LAZ97_RS12810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LAZ97_RS12815	COG2384	SAM-dependent methyltransferase
LAZ97_RS12820	COG2010	Cytochrome c
LAZ97_RS12825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LAZ97_RS12830	COG0358	DNA primase activity
LAZ97_RS12845	COG0517	IMP dehydrogenase activity
LAZ97_RS12850	COG0751	glycine-tRNA ligase activity
LAZ97_RS12870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LAZ97_RS12875	COG0295	cytidine deaminase activity
LAZ97_RS12880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LAZ97_RS12890	COG1480	7TM receptor with intracellular HD hydrolase
LAZ97_RS12895	COG1702	phosphate starvation-inducible protein PhoH
LAZ97_RS12900	COG0561	phosphatase activity
LAZ97_RS12915	COG4864	UPF0365 protein
LAZ97_RS12920	COG1030	water channel activity
LAZ97_RS12925	COG1610	YqeY-like protein
LAZ97_RS12935	COG1283	sodium-dependent phosphate transmembrane transporter activity
LAZ97_RS12940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LAZ97_RS12945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LAZ97_RS12975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LAZ97_RS12990	COG0860	N-Acetylmuramoyl-L-alanine amidase
LAZ97_RS13020	COG0658	competence protein
LAZ97_RS13020	COG2333	competence protein COMEC
LAZ97_RS13025	COG2131	deaminase
LAZ97_RS13030	COG1596	polysaccharide export
LAZ97_RS13030	COG1555	photosystem II stabilization
LAZ97_RS13035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LAZ97_RS13040	COG2226	methyltransferase
LAZ97_RS13045	COG0799	negative regulation of ribosome biogenesis
LAZ97_RS13050	COG1713	HD superfamily hydrolase involved in NAD metabolism
LAZ97_RS13060	COG1534	Rna-binding protein
LAZ97_RS13065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LAZ97_RS13070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LAZ97_RS13075	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LAZ97_RS13085	COG2755	lipolytic protein G-D-S-L family
LAZ97_RS13095	COG0398	Pfam SNARE associated Golgi protein
LAZ97_RS13120	COG5444	nuclease activity
LAZ97_RS13125	COG4282	regulation of fungal-type cell wall biogenesis
LAZ97_RS13140	COG2207	Transcriptional regulator
LAZ97_RS13140	COG3708	Transcriptional regulator
LAZ97_RS13145	COG0583	DNA-binding transcription factor activity
LAZ97_RS13160	COG0642	Histidine kinase
LAZ97_RS13160	COG5002	protein histidine kinase activity
LAZ97_RS13165	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS13170	COG2311	Membrane
LAZ97_RS13175	COG0454	-acetyltransferase
LAZ97_RS13180	COG0563	adenylate kinase activity
LAZ97_RS13190	COG2814	Major facilitator Superfamily
LAZ97_RS13200	COG0456	acetyltransferase
LAZ97_RS13205	COG2318	DinB family
LAZ97_RS13215	COG0561	phosphatase activity
LAZ97_RS13220	COG0561	phosphatase activity
LAZ97_RS13230	COG1482	cell wall glycoprotein biosynthetic process
LAZ97_RS13235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LAZ97_RS13235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LAZ97_RS13235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LAZ97_RS13240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LAZ97_RS13240	COG3711	transcriptional antiterminator
LAZ97_RS13250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LAZ97_RS13255	COG0583	DNA-binding transcription factor activity
LAZ97_RS13260	COG2814	Major facilitator Superfamily
LAZ97_RS13265	COG2124	cytochrome p450
LAZ97_RS13265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LAZ97_RS13270	COG1309	transcriptional regulator
LAZ97_RS13275	COG2226	methyltransferase
LAZ97_RS13290	COG2116	formate transmembrane transporter activity
LAZ97_RS13295	COG5609	conserved protein (DUF2294)
LAZ97_RS13300	COG3383	formate dehydrogenase (NAD+) activity
LAZ97_RS13305	COG2427	Protein of unknown function (DUF1641)
LAZ97_RS13315	COG0626	cystathionine gamma-synthase activity
LAZ97_RS13320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LAZ97_RS13345	COG0768	penicillin binding
LAZ97_RS13360	COG0826	peptidase U32
LAZ97_RS13365	COG0826	peptidase U32
LAZ97_RS13370	COG4122	O-methyltransferase activity
LAZ97_RS13375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LAZ97_RS13400	COG0628	permease
LAZ97_RS13405	COG1126	abc transporter atp-binding protein
LAZ97_RS13410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LAZ97_RS13415	COG0765	amino acid transport
LAZ97_RS13420	COG0765	amino acid transport
LAZ97_RS13435	COG3881	PFAM PRC-barrel domain
LAZ97_RS13440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LAZ97_RS13445	COG0457	Tetratricopeptide repeat
LAZ97_RS13455	COG1104	cysteine desulfurase activity
LAZ97_RS13460	COG1959	2 iron, 2 sulfur cluster binding
LAZ97_RS13465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LAZ97_RS13470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LAZ97_RS13495	COG0860	N-Acetylmuramoyl-L-alanine amidase
LAZ97_RS13495	COG3103	Sh3 type 3 domain protein
LAZ97_RS13495	COG4991	sh3 domain protein
LAZ97_RS13505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LAZ97_RS13515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LAZ97_RS13515	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LAZ97_RS13520	COG5416	Lipopolysaccharide assembly protein A domain
LAZ97_RS13525	COG0490	domain, Protein
LAZ97_RS13530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LAZ97_RS13530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LAZ97_RS13540	COG2244	polysaccharide biosynthetic process
LAZ97_RS13545	COG2323	membrane
LAZ97_RS13555	COG1862	Preprotein translocase
LAZ97_RS13595	COG1388	LysM domain
LAZ97_RS13605	COG0157	Belongs to the NadC ModD family
LAZ97_RS13610	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LAZ97_RS13615	COG1104	cysteine desulfurase activity
LAZ97_RS13620	COG1827	regulation of RNA biosynthetic process
LAZ97_RS13625	COG0077	Prephenate dehydratase
LAZ97_RS13640	COG3290	protein histidine kinase activity
LAZ97_RS13645	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LAZ97_RS13650	COG2868	ribosomal protein
LAZ97_RS13660	COG1994	Peptidase M50
LAZ97_RS13665	COG0739	heme binding
LAZ97_RS13670	COG2894	cell division
LAZ97_RS13680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LAZ97_RS13690	COG1077	Cell shape determining protein MreB Mrl
LAZ97_RS13720	COG4824	toxin secretion phage lysis holin
LAZ97_RS13740	COG5434	Belongs to the glycosyl hydrolase 28 family
LAZ97_RS13745	COG1705	Flagellar rod assembly protein muramidase FlgJ
LAZ97_RS13755	COG3953	SLT domain
LAZ97_RS13755	COG5412	phage tail tape measure protein
LAZ97_RS13855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LAZ97_RS13855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LAZ97_RS13900	COG1396	sequence-specific DNA binding
LAZ97_RS13930	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LAZ97_RS13935	COG0285	dihydrofolate synthase activity
LAZ97_RS13940	COG0525	valine-tRNA ligase activity
LAZ97_RS13950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LAZ97_RS13955	COG1388	LysM domain
LAZ97_RS13965	COG0113	porphobilinogen synthase activity
LAZ97_RS13970	COG1587	Uroporphyrinogen-III synthase
LAZ97_RS13980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LAZ97_RS14000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LAZ97_RS14005	COG0470	DNA polymerase III
LAZ97_RS14005	COG1067	ATP-dependent peptidase activity
LAZ97_RS14020	COG0457	Tetratricopeptide repeat
LAZ97_RS14020	COG1477	protein flavinylation
LAZ97_RS14035	COG0473	3-isopropylmalate dehydrogenase activity
LAZ97_RS14050	COG0440	acetolactate synthase activity
LAZ97_RS14055	COG0028	Belongs to the TPP enzyme family
LAZ97_RS14085	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LAZ97_RS14110	COG0622	Phosphoesterase
LAZ97_RS14115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LAZ97_RS14125	COG5401	PFAM Sporulation and spore germination
LAZ97_RS14140	COG2197	response regulator
LAZ97_RS14145	COG0824	Thioesterase
LAZ97_RS14150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LAZ97_RS14155	COG1053	succinate dehydrogenase
LAZ97_RS14160	COG2009	succinate dehydrogenase
LAZ97_RS14165	COG1719	4-vinyl reductase, 4VR
LAZ97_RS14170	COG0527	aspartate kinase activity
LAZ97_RS14180	COG3118	belongs to the thioredoxin family
LAZ97_RS14185	COG3534	alpha-L-arabinofuranosidase
LAZ97_RS14190	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LAZ97_RS14195	COG2086	electron transfer activity
LAZ97_RS14200	COG1024	Enoyl-CoA hydratase
LAZ97_RS14205	COG1309	transcriptional regulator
LAZ97_RS14210	COG0318	PFAM AMP-dependent synthetase and ligase
LAZ97_RS14220	COG3766	membrane
LAZ97_RS14230	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LAZ97_RS14230	COG1796	DNA polymerase
LAZ97_RS14235	COG1286	toxin biosynthetic process
LAZ97_RS14250	COG0072	phenylalanine-tRNA ligase activity
LAZ97_RS14250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LAZ97_RS14255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LAZ97_RS14260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LAZ97_RS14270	COG3835	regulator
LAZ97_RS14275	COG0277	FAD linked oxidase domain protein
LAZ97_RS14280	COG0247	lactate metabolic process
LAZ97_RS14285	COG1966	Carbon starvation protein
LAZ97_RS14290	COG3534	alpha-L-arabinofuranosidase
LAZ97_RS14295	COG0395	ABC-type sugar transport system, permease component
LAZ97_RS14300	COG1175	transmembrane transport
LAZ97_RS14305	COG1653	transport
LAZ97_RS14315	COG0647	UMP catabolic process
LAZ97_RS14320	COG0235	Class ii aldolase
LAZ97_RS14325	COG1069	ribulokinase activity
LAZ97_RS14330	COG2160	L-arabinose isomerase activity
LAZ97_RS14335	COG3507	Belongs to the glycosyl hydrolase 43 family
LAZ97_RS14340	COG1363	Peptidase, m42
LAZ97_RS14350	COG3326	Membrane
LAZ97_RS14365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LAZ97_RS14370	COG1346	cytolysis
LAZ97_RS14375	COG1380	Effector of murein hydrolase LrgA
LAZ97_RS14380	COG3279	Response regulator of the LytR AlgR family
LAZ97_RS14385	COG3275	phosphorelay sensor kinase activity
LAZ97_RS14390	COG1011	Hydrolase
LAZ97_RS14405	COG0398	Pfam SNARE associated Golgi protein
LAZ97_RS14410	COG1484	DNA-dependent DNA replication
LAZ97_RS14415	COG3611	Membrane attachment protein
LAZ97_RS14430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LAZ97_RS14435	COG1733	regulation of RNA biosynthetic process
LAZ97_RS14440	COG2814	Major facilitator Superfamily
LAZ97_RS14445	COG0656	L-ascorbic acid biosynthetic process
LAZ97_RS14450	COG0237	dephospho-CoA kinase activity
LAZ97_RS14455	COG1971	Probably functions as a manganese efflux pump
LAZ97_RS14460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LAZ97_RS14465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LAZ97_RS14465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LAZ97_RS14470	COG5002	protein histidine kinase activity
LAZ97_RS14475	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS14485	COG0538	isocitrate dehydrogenase activity
LAZ97_RS14490	COG0372	Belongs to the citrate synthase family
LAZ97_RS14500	COG0457	Tetratricopeptide repeat
LAZ97_RS14535	COG0628	permease
LAZ97_RS14540	COG3030	protein affecting phage T7 exclusion by the F plasmid
LAZ97_RS14545	COG0469	pyruvate kinase activity
LAZ97_RS14565	COG0281	malic enzyme
LAZ97_RS14570	COG0587	DNA-directed DNA polymerase activity
LAZ97_RS14590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LAZ97_RS14600	COG4109	DRTGG domain
LAZ97_RS14610	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS14625	COG0521	Mo-molybdopterin cofactor biosynthetic process
LAZ97_RS14635	COG0827	DNA restriction-modification system
LAZ97_RS14640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LAZ97_RS14645	COG3874	Sporulation protein YtfJ
LAZ97_RS14655	COG1714	RDD family
LAZ97_RS14660	COG0616	signal peptide processing
LAZ97_RS14665	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LAZ97_RS14670	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LAZ97_RS14675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LAZ97_RS14690	COG1104	cysteine desulfurase activity
LAZ97_RS14695	COG1114	Component of the transport system for branched-chain amino acids
LAZ97_RS14705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LAZ97_RS14710	COG1309	transcriptional regulator
LAZ97_RS14715	COG1956	GAF domain-containing protein
LAZ97_RS14720	COG2199	diguanylate cyclase activity
LAZ97_RS14720	COG2203	Gaf domain
LAZ97_RS14730	COG1012	belongs to the aldehyde dehydrogenase family
LAZ97_RS14735	COG4282	regulation of fungal-type cell wall biogenesis
LAZ97_RS14785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LAZ97_RS14785	COG1017	nitric oxide dioxygenase activity
LAZ97_RS14800	COG0693	protein deglycase activity
LAZ97_RS14815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LAZ97_RS14820	COG1378	Sugar-specific transcriptional regulator TrmB
LAZ97_RS14840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LAZ97_RS14845	COG0454	-acetyltransferase
LAZ97_RS14850	COG0517	IMP dehydrogenase activity
LAZ97_RS14855	COG0123	including yeast histone deacetylase and acetoin utilization protein
LAZ97_RS14860	COG1360	Flagellar Motor Protein
LAZ97_RS14865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LAZ97_RS14870	COG1609	Transcriptional regulator
LAZ97_RS14875	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LAZ97_RS14875	COG1605	Chorismate mutase
LAZ97_RS14880	COG3118	belongs to the thioredoxin family
LAZ97_RS14885	COG4980	gas vesicle protein
LAZ97_RS14890	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LAZ97_RS14900	COG1674	ftsk spoiiie
LAZ97_RS14905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LAZ97_RS14915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LAZ97_RS14935	COG1363	Peptidase, m42
LAZ97_RS14940	COG5584	Small secreted protein
LAZ97_RS14945	COG0281	malic enzyme
LAZ97_RS14950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LAZ97_RS14965	COG0510	thiamine kinase activity
LAZ97_RS14970	COG1597	lipid kinase activity
LAZ97_RS14980	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LAZ97_RS14985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LAZ97_RS14990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LAZ97_RS14995	COG2252	PERMEase
LAZ97_RS15000	COG4473	ABC transporter
LAZ97_RS15005	COG1131	(ABC) transporter
LAZ97_RS15010	COG1349	DNA-binding transcription factor activity
LAZ97_RS15015	COG1187	pseudouridine synthase activity
LAZ97_RS15020	COG2244	polysaccharide biosynthetic process
LAZ97_RS15025	COG2081	HI0933 family
LAZ97_RS15030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LAZ97_RS15045	COG1609	Transcriptional regulator
LAZ97_RS15050	COG1653	transport
LAZ97_RS15055	COG1175	transmembrane transport
LAZ97_RS15060	COG0395	ABC-type sugar transport system, permease component
LAZ97_RS15065	COG1486	melibiose metabolic process
LAZ97_RS15075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LAZ97_RS15090	COG1366	Belongs to the anti-sigma-factor antagonist family
LAZ97_RS15090	COG2202	Pas domain
LAZ97_RS15095	COG2814	Major facilitator Superfamily
LAZ97_RS15100	COG5522	Integral membrane protein (intg_mem_TP0381)
LAZ97_RS15105	COG0577	efflux transmembrane transporter activity
LAZ97_RS15110	COG1136	(ABC) transporter
LAZ97_RS15115	COG2205	protein histidine kinase activity
LAZ97_RS15120	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS15125	COG0577	efflux transmembrane transporter activity
LAZ97_RS15130	COG1136	(ABC) transporter
LAZ97_RS15150	COG1131	(ABC) transporter
LAZ97_RS15155	COG1725	Transcriptional regulator
LAZ97_RS15170	COG0640	Transcriptional regulator
LAZ97_RS15175	COG0477	Major facilitator Superfamily
LAZ97_RS15180	COG1242	4 iron, 4 sulfur cluster binding
LAZ97_RS15185	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LAZ97_RS15195	COG0584	glycerophosphoryl diester phosphodiesterase
LAZ97_RS15205	COG2267	carboxylic ester hydrolase activity
LAZ97_RS15210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LAZ97_RS15215	COG1113	amino acid transport
LAZ97_RS15220	COG0367	asparagine synthase
LAZ97_RS15240	COG1506	peptidase
LAZ97_RS15245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LAZ97_RS15250	COG1116	anion transmembrane transporter activity
LAZ97_RS15255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LAZ97_RS15260	COG0494	nUDIX hydrolase
LAZ97_RS15265	COG4824	toxin secretion phage lysis holin
LAZ97_RS15270	COG0783	Belongs to the Dps family
LAZ97_RS15295	COG0288	reversible hydration of carbon dioxide
LAZ97_RS15305	COG1271	oxidase subunit
LAZ97_RS15310	COG1294	oxidase, subunit
LAZ97_RS15320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LAZ97_RS15325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LAZ97_RS15325	COG1321	iron dependent repressor
LAZ97_RS15330	COG1121	(ABC) transporter
LAZ97_RS15335	COG0803	Belongs to the bacterial solute-binding protein 9 family
LAZ97_RS15340	COG4948	Mandelate Racemase Muconate Lactonizing
LAZ97_RS15350	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LAZ97_RS15355	COG0596	Alpha beta hydrolase
LAZ97_RS15365	COG1169	isochorismate synthase
LAZ97_RS15370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LAZ97_RS15375	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LAZ97_RS15500	COG3859	Proton-coupled thiamine transporter YuaJ
LAZ97_RS15505	COG2268	Band 7 protein
LAZ97_RS15510	COG1585	Membrane protein implicated in regulation of membrane protease activity
LAZ97_RS15515	COG2318	DinB family
LAZ97_RS15525	COG1454	alcohol dehydrogenase
LAZ97_RS15530	COG1012	belongs to the aldehyde dehydrogenase family
LAZ97_RS15535	COG1510	regulation of RNA biosynthetic process
LAZ97_RS15545	COG0569	domain protein
LAZ97_RS15550	COG1705	Flagellar rod assembly protein muramidase FlgJ
LAZ97_RS15555	COG1017	nitric oxide dioxygenase activity
LAZ97_RS15555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LAZ97_RS15570	COG0457	Tetratricopeptide repeat
LAZ97_RS15610	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LAZ97_RS15625	COG0628	permease
LAZ97_RS15630	COG0673	inositol 2-dehydrogenase activity
LAZ97_RS15635	COG0693	protein deglycase activity
LAZ97_RS15640	COG0840	transmembrane signaling receptor activity
LAZ97_RS15650	COG0840	transmembrane signaling receptor activity
LAZ97_RS15655	COG0840	transmembrane signaling receptor activity
LAZ97_RS15670	COG2070	2-Nitropropane dioxygenase
LAZ97_RS15675	COG0432	Pfam Uncharacterised protein family UPF0047
LAZ97_RS15680	COG0366	Alpha amylase catalytic
LAZ97_RS15685	COG1253	flavin adenine dinucleotide binding
LAZ97_RS15690	COG2738	Putative neutral zinc metallopeptidase
LAZ97_RS15705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LAZ97_RS15730	COG1335	isochorismatase
LAZ97_RS15745	COG2155	Conserved Protein
LAZ97_RS15755	COG1098	S1 RNA binding domain
LAZ97_RS15760	COG0436	Aminotransferase
LAZ97_RS15765	COG1522	sequence-specific DNA binding
LAZ97_RS15770	COG2267	carboxylic ester hydrolase activity
LAZ97_RS15780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LAZ97_RS15785	COG2205	protein histidine kinase activity
LAZ97_RS15795	COG5018	Exonuclease
LAZ97_RS15800	COG2814	Major facilitator Superfamily
LAZ97_RS15805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LAZ97_RS15810	COG3011	Protein conserved in bacteria
LAZ97_RS15820	COG3290	protein histidine kinase activity
LAZ97_RS15825	COG4565	transcriptional regulatory protein
LAZ97_RS15830	COG1744	ABC transporter substrate-binding protein PnrA-like
LAZ97_RS15835	COG3845	ABC transporter
LAZ97_RS15840	COG4603	Belongs to the binding-protein-dependent transport system permease family
LAZ97_RS15845	COG1079	Belongs to the binding-protein-dependent transport system permease family
LAZ97_RS15855	COG2111	Na H antiporter
LAZ97_RS15855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LAZ97_RS15860	COG2111	Na H antiporter
LAZ97_RS15865	COG1006	Multisubunit Na H antiporter MnhC subunit
LAZ97_RS15870	COG0651	ATP synthesis coupled electron transport
LAZ97_RS15875	COG1863	multisubunit Na H antiporter MnhE subunit
LAZ97_RS15880	COG2212	antiporter activity
LAZ97_RS15885	COG1320	monovalent cation:proton antiporter activity
LAZ97_RS15890	COG2050	protein possibly involved in aromatic compounds catabolism
LAZ97_RS15895	COG2197	response regulator
LAZ97_RS15900	COG4585	Histidine kinase
LAZ97_RS15910	COG0142	geranyltranstransferase activity
LAZ97_RS15925	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LAZ97_RS15930	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LAZ97_RS15935	COG1335	isochorismatase
LAZ97_RS15940	COG5506	Protein of unknown function (DUF1694)
LAZ97_RS15955	COG0628	permease
LAZ97_RS15965	COG1418	mRNA catabolic process
LAZ97_RS15970	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS15980	COG1511	domain protein
LAZ97_RS15985	COG1674	ftsk spoiiie
LAZ97_RS15985	COG0433	COG0433 Predicted ATPase
LAZ97_RS15990	COG4499	WXG100 protein secretion system (Wss), protein YukC
LAZ97_RS15995	COG5417	Belongs to the EsaB family
LAZ97_RS16000	COG4842	Belongs to the WXG100 family
LAZ97_RS16005	COG2508	Transcriptional regulator
LAZ97_RS16005	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LAZ97_RS16010	COG0686	Belongs to the AlaDH PNT family
LAZ97_RS16015	COG5634	Uncharacterized conserved protein (DUF2278)
LAZ97_RS16020	COG3251	PFAM MbtH domain protein
LAZ97_RS16025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LAZ97_RS16030	COG1535	isochorismatase
LAZ97_RS16030	COG3433	isochorismatase activity
LAZ97_RS16035	COG1021	2,3-dihydroxybenzoate-AMP ligase
LAZ97_RS16040	COG1169	isochorismate synthase
LAZ97_RS16045	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS16050	COG2819	hydrolase of the alpha beta superfamily
LAZ97_RS16055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LAZ97_RS16060	COG1268	BioY protein
LAZ97_RS16065	COG2056	Na+-H+ antiporter family
LAZ97_RS16075	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LAZ97_RS16080	COG3584	3D domain protein
LAZ97_RS16095	COG1252	NADH dehydrogenase
LAZ97_RS16125	COG1131	(ABC) transporter
LAZ97_RS16145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LAZ97_RS16150	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LAZ97_RS16155	COG0316	Belongs to the HesB IscA family
LAZ97_RS16165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LAZ97_RS16175	COG1252	NADH dehydrogenase
LAZ97_RS16180	COG4837	Protein of unknown function (DUF1462)
LAZ97_RS16185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LAZ97_RS16190	COG0823	Involved in the tonB-independent uptake of proteins
LAZ97_RS16190	COG1506	peptidase
LAZ97_RS16190	COG4946	Tricorn protease homolog
LAZ97_RS16200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LAZ97_RS16205	COG0460	homoserine dehydrogenase
LAZ97_RS16210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LAZ97_RS16215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LAZ97_RS16220	COG0647	UMP catabolic process
LAZ97_RS16225	COG2445	Protein of unknown function DUF86
LAZ97_RS16230	COG4470	Protein conserved in bacteria
LAZ97_RS16240	COG0739	heme binding
LAZ97_RS16250	COG0737	Belongs to the 5'-nucleotidase family
LAZ97_RS16255	COG0730	response to heat
LAZ97_RS16260	COG1801	Protein of unknown function DUF72
LAZ97_RS16275	COG2508	Transcriptional regulator
LAZ97_RS16280	COG0457	Tetratricopeptide repeat
LAZ97_RS16295	COG2814	Major facilitator Superfamily
LAZ97_RS16300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LAZ97_RS16305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LAZ97_RS16310	COG2356	endonuclease I
LAZ97_RS16315	COG3842	ATPase activity
LAZ97_RS16320	COG2188	Transcriptional regulator
LAZ97_RS16325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LAZ97_RS16330	COG0395	ABC-type sugar transport system, permease component
LAZ97_RS16335	COG1175	transmembrane transport
LAZ97_RS16340	COG1653	transport
LAZ97_RS16345	COG2222	sugar isomerase
LAZ97_RS16350	COG0789	Transcriptional regulator
LAZ97_RS16375	COG0322	excinuclease ABC activity
LAZ97_RS16380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LAZ97_RS16385	COG2226	methyltransferase
LAZ97_RS16395	COG3409	Peptidoglycan-binding domain 1 protein
LAZ97_RS16400	COG0719	Fe-S assembly protein
LAZ97_RS16405	COG0822	iron-sulfur transferase activity
LAZ97_RS16410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LAZ97_RS16415	COG0719	Fe-S assembly protein
LAZ97_RS16420	COG0396	ATPase activity
LAZ97_RS16430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LAZ97_RS16435	COG1464	Belongs to the NlpA lipoprotein family
LAZ97_RS16440	COG2011	ABC-type metal ion transport system permease component
LAZ97_RS16445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LAZ97_RS16455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LAZ97_RS16460	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LAZ97_RS16475	COG1393	Belongs to the ArsC family
LAZ97_RS16480	COG1960	acyl-CoA dehydrogenase activity
LAZ97_RS16485	COG0183	Belongs to the thiolase family
LAZ97_RS16490	COG1024	Enoyl-CoA hydratase
LAZ97_RS16490	COG1250	3-hydroxyacyl-CoA dehydrogenase
LAZ97_RS16510	COG5577	PFAM Coat F domain
LAZ97_RS16515	COG1846	Transcriptional regulator
LAZ97_RS16520	COG0477	Major facilitator Superfamily
LAZ97_RS16550	COG1120	ATPase activity
LAZ97_RS16565	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS16570	COG0783	Belongs to the Dps family
LAZ97_RS16575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LAZ97_RS16580	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS16585	COG2205	protein histidine kinase activity
LAZ97_RS16585	COG2770	Histidine kinase
LAZ97_RS16595	COG1309	transcriptional regulator
LAZ97_RS16600	COG0114	fumarate hydratase activity
LAZ97_RS16610	COG0697	spore germination
LAZ97_RS16615	COG0814	amino acid
LAZ97_RS16625	COG2197	response regulator
LAZ97_RS16630	COG4585	Histidine kinase
LAZ97_RS16635	COG4758	membrane
LAZ97_RS16640	COG3595	metallopeptidase activity
LAZ97_RS16645	COG1842	Phage shock protein A
LAZ97_RS16650	COG4758	membrane
LAZ97_RS16655	COG2814	Major facilitator Superfamily
LAZ97_RS16660	COG2096	Adenosyltransferase
LAZ97_RS16665	COG1120	ATPase activity
LAZ97_RS16670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LAZ97_RS16675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LAZ97_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS16685	COG3386	PFAM SMP-30 Gluconolaconase
LAZ97_RS16690	COG2205	protein histidine kinase activity
LAZ97_RS16695	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS16705	COG1191	sigma factor activity
LAZ97_RS16715	COG2140	Oxalate decarboxylase
LAZ97_RS16725	COG1120	ATPase activity
LAZ97_RS16730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LAZ97_RS16735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LAZ97_RS16740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LAZ97_RS16745	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LAZ97_RS16750	COG0531	amino acid
LAZ97_RS16760	COG1988	membrane-bound metal-dependent
LAZ97_RS16770	COG1910	domain protein
LAZ97_RS16775	COG0725	ABC transporter, periplasmic molybdate-binding protein
LAZ97_RS16780	COG4149	molybdate abc transporter
LAZ97_RS16785	COG2197	response regulator
LAZ97_RS16790	COG3850	Histidine kinase
LAZ97_RS16795	COG1131	(ABC) transporter
LAZ97_RS16805	COG0842	Transport permease protein
LAZ97_RS16810	COG0656	L-ascorbic acid biosynthetic process
LAZ97_RS16830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LAZ97_RS16835	COG3973	AAA domain
LAZ97_RS16840	COG2860	membrane
LAZ97_RS16850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LAZ97_RS16855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LAZ97_RS16860	COG2217	Heavy metal translocating P-type atpase
LAZ97_RS16865	COG2217	Heavy metal translocating P-type atpase
LAZ97_RS16870	COG2608	mercury ion transmembrane transporter activity
LAZ97_RS16875	COG1937	Protein conserved in bacteria
LAZ97_RS16880	COG0673	inositol 2-dehydrogenase activity
LAZ97_RS16890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LAZ97_RS16895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LAZ97_RS16900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LAZ97_RS16905	COG1126	abc transporter atp-binding protein
LAZ97_RS16910	COG0765	amino acid transport
LAZ97_RS16915	COG0765	amino acid transport
LAZ97_RS16920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LAZ97_RS16925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LAZ97_RS16930	COG0454	-acetyltransferase
LAZ97_RS16935	COG0583	DNA-binding transcription factor activity
LAZ97_RS16940	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS16945	COG2732	(Barnase) inhibitor
LAZ97_RS16950	COG2732	(Barnase) inhibitor
LAZ97_RS16970	COG4824	toxin secretion phage lysis holin
LAZ97_RS16990	COG5434	Belongs to the glycosyl hydrolase 28 family
LAZ97_RS16995	COG1388	LysM domain
LAZ97_RS16995	COG1705	Flagellar rod assembly protein muramidase FlgJ
LAZ97_RS17075	COG1802	Transcriptional regulator
LAZ97_RS17075	COG4626	Terminase
LAZ97_RS17105	COG0582	viral genome integration into host DNA
LAZ97_RS17110	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LAZ97_RS17250	COG0582	viral genome integration into host DNA
LAZ97_RS17265	COG0557	exoribonuclease II activity
LAZ97_RS17270	COG1647	Serine aminopeptidase, S33
LAZ97_RS17275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LAZ97_RS17280	COG1476	TRANSCRIPTIONal
LAZ97_RS17285	COG1396	sequence-specific DNA binding
LAZ97_RS17290	COG1396	sequence-specific DNA binding
LAZ97_RS17295	COG1733	regulation of RNA biosynthetic process
LAZ97_RS17320	COG1131	(ABC) transporter
LAZ97_RS17325	COG1174	glycine betaine transport
LAZ97_RS17330	COG1732	Glycine betaine
LAZ97_RS17335	COG1174	glycine betaine transport
LAZ97_RS17340	COG0517	IMP dehydrogenase activity
LAZ97_RS17340	COG1125	glycine betaine transport
LAZ97_RS17345	COG1510	regulation of RNA biosynthetic process
LAZ97_RS17350	COG1174	glycine betaine transport
LAZ97_RS17355	COG1732	Glycine betaine
LAZ97_RS17360	COG1174	glycine betaine transport
LAZ97_RS17365	COG0517	IMP dehydrogenase activity
LAZ97_RS17365	COG1125	glycine betaine transport
LAZ97_RS17370	COG1510	regulation of RNA biosynthetic process
LAZ97_RS17375	COG2095	MarC family integral membrane protein
LAZ97_RS17380	COG3064	Membrane
LAZ97_RS17390	COG0456	acetyltransferase
LAZ97_RS17410	COG0126	phosphoglycerate kinase activity
LAZ97_RS17415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LAZ97_RS17420	COG2390	Transcriptional regulator
LAZ97_RS17425	COG2814	Major facilitator Superfamily
LAZ97_RS17430	COG1609	Transcriptional regulator
LAZ97_RS17435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LAZ97_RS17440	COG0583	DNA-binding transcription factor activity
LAZ97_RS17445	COG0697	spore germination
LAZ97_RS17455	COG1113	amino acid transport
LAZ97_RS17465	COG1737	Transcriptional regulator
LAZ97_RS17470	COG1070	Carbohydrate kinase
LAZ97_RS17495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LAZ97_RS17500	COG2186	Transcriptional regulator
LAZ97_RS17505	COG1620	l-lactate permease
LAZ97_RS17510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LAZ97_RS17520	COG5039	Polysaccharide pyruvyl transferase
LAZ97_RS17525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LAZ97_RS17530	COG0110	maltose O-acetyltransferase activity
LAZ97_RS17535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LAZ97_RS17540	COG2244	polysaccharide biosynthetic process
LAZ97_RS17545	COG1216	Glycosyl transferase, family 2
LAZ97_RS17550	COG5039	Polysaccharide pyruvyl transferase
LAZ97_RS17555	COG1216	Glycosyl transferase, family 2
LAZ97_RS17565	COG0438	transferase activity, transferring glycosyl groups
LAZ97_RS17570	COG1215	transferase activity, transferring glycosyl groups
LAZ97_RS17575	COG0438	transferase activity, transferring glycosyl groups
LAZ97_RS17580	COG1086	Polysaccharide biosynthesis protein
LAZ97_RS17585	COG0489	protein tyrosine kinase activity
LAZ97_RS17590	COG3944	biosynthesis protein
LAZ97_RS17595	COG1396	sequence-specific DNA binding
LAZ97_RS17600	COG2272	Belongs to the type-B carboxylesterase lipase family
LAZ97_RS17610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LAZ97_RS17620	COG0456	acetyltransferase
LAZ97_RS17625	COG3479	Phenolic acid decarboxylase
LAZ97_RS17665	COG2223	nitrite transmembrane transporter activity
LAZ97_RS17670	COG1609	Transcriptional regulator
LAZ97_RS17680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LAZ97_RS17685	COG0366	Alpha amylase catalytic
LAZ97_RS17690	COG1554	hydrolase, family 65, central catalytic
LAZ97_RS17695	COG5521	maltodextrose utilization protein MalA
LAZ97_RS17700	COG3833	ABC-type maltose transport systems, permease component
LAZ97_RS17705	COG1175	transmembrane transport
LAZ97_RS17710	COG2182	Extracellular solute-binding protein
LAZ97_RS17715	COG0366	Alpha amylase catalytic
LAZ97_RS17720	COG1609	Transcriptional regulator
LAZ97_RS17730	COG1694	Mazg nucleotide pyrophosphohydrolase
LAZ97_RS17735	COG0659	secondary active sulfate transmembrane transporter activity
LAZ97_RS17740	COG0288	reversible hydration of carbon dioxide
LAZ97_RS17745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAZ97_RS17750	COG4290	ribonuclease
LAZ97_RS17755	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LAZ97_RS17760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LAZ97_RS17770	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LAZ97_RS17780	COG1051	belongs to the nudix hydrolase family
LAZ97_RS17785	COG0492	ferredoxin-NADP+ reductase activity
LAZ97_RS17790	COG3883	PFAM NLP P60 protein
LAZ97_RS17790	COG0791	NLP P60 protein
LAZ97_RS17795	COG0457	Tetratricopeptide repeat
LAZ97_RS17800	COG5002	protein histidine kinase activity
LAZ97_RS17805	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS17810	COG1132	(ABC) transporter
LAZ97_RS17815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LAZ97_RS17815	COG0140	phosphoribosyl-ATP diphosphatase activity
LAZ97_RS17840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LAZ97_RS17855	COG4990	cell redox homeostasis
LAZ97_RS17860	COG0110	maltose O-acetyltransferase activity
LAZ97_RS17880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LAZ97_RS17890	COG2188	Transcriptional regulator
LAZ97_RS17895	COG1309	transcriptional regulator
LAZ97_RS17900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LAZ97_RS17905	COG1950	PFAM Membrane protein of
LAZ97_RS17910	COG1983	PspC domain protein
LAZ97_RS17915	COG3595	metallopeptidase activity
LAZ97_RS17930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LAZ97_RS17940	COG4897	Protein conserved in bacteria
LAZ97_RS17945	COG3848	Pyruvate phosphate dikinase
LAZ97_RS17945	COG0574	Belongs to the PEP-utilizing enzyme family
LAZ97_RS17950	COG1309	transcriptional regulator
LAZ97_RS17955	COG2814	Major facilitator Superfamily
LAZ97_RS17970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LAZ97_RS17980	COG3409	Peptidoglycan-binding domain 1 protein
LAZ97_RS17980	COG0793	Belongs to the peptidase S41A family
LAZ97_RS17985	COG3420	alginic acid biosynthetic process
LAZ97_RS17990	COG2177	Part of the ABC transporter FtsEX involved in
LAZ97_RS17995	COG2884	Cell division ATP-binding protein ftsE
LAZ97_RS18000	COG2010	Cytochrome c
LAZ97_RS18005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAZ97_RS18020	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LAZ97_RS18035	COG1516	flagellar protein fliS
LAZ97_RS18040	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LAZ97_RS18045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LAZ97_RS18070	COG1256	bacterial-type flagellum assembly
LAZ97_RS18070	COG4786	Flagellar basal body rod
LAZ97_RS18075	COG3418	PFAM FlgN family protein
LAZ97_RS18090	COG1040	competence protein
LAZ97_RS18100	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LAZ97_RS18105	COG1307	EDD domain protein, DegV family
LAZ97_RS18110	COG2197	response regulator
LAZ97_RS18115	COG4585	Histidine kinase
LAZ97_RS18120	COG1739	Uncharacterized protein family UPF0029
LAZ97_RS18125	COG1316	TRANSCRIPTIONal
LAZ97_RS18130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LAZ97_RS18135	COG0438	transferase activity, transferring glycosyl groups
LAZ97_RS18140	COG1215	transferase activity, transferring glycosyl groups
LAZ97_RS18145	COG3206	protein involved in exopolysaccharide biosynthesis
LAZ97_RS18150	COG3307	-O-antigen
LAZ97_RS18155	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LAZ97_RS18160	COG0297	glycogen (starch) synthase activity
LAZ97_RS18160	COG0438	transferase activity, transferring glycosyl groups
LAZ97_RS18165	COG2244	polysaccharide biosynthetic process
LAZ97_RS18175	COG2247	cell wall binding repeat
LAZ97_RS18175	COG0860	N-Acetylmuramoyl-L-alanine amidase
LAZ97_RS18180	COG2385	sporulation resulting in formation of a cellular spore
LAZ97_RS18180	COG2247	cell wall binding repeat
LAZ97_RS18190	COG1316	TRANSCRIPTIONal
LAZ97_RS18195	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LAZ97_RS18200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LAZ97_RS18205	COG1134	teichoic acid transport
LAZ97_RS18210	COG1682	transport, permease protein
LAZ97_RS18215	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LAZ97_RS18220	COG0438	transferase activity, transferring glycosyl groups
LAZ97_RS18225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LAZ97_RS18230	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LAZ97_RS18235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LAZ97_RS18240	COG4193	domain, Protein
LAZ97_RS18245	COG1482	cell wall glycoprotein biosynthetic process
LAZ97_RS18250	COG0697	spore germination
LAZ97_RS18255	COG0814	amino acid
LAZ97_RS18270	COG2814	Major facilitator Superfamily
LAZ97_RS18275	COG1316	TRANSCRIPTIONal
LAZ97_RS18280	COG0561	phosphatase activity
LAZ97_RS18285	COG2433	Pfam Transposase IS66
LAZ97_RS18290	COG0791	NLP P60 protein
LAZ97_RS18300	COG2843	Capsule synthesis protein
LAZ97_RS18310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LAZ97_RS18315	COG0697	spore germination
LAZ97_RS18320	COG0814	amino acid
LAZ97_RS18330	COG1609	Transcriptional regulator
LAZ97_RS18335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LAZ97_RS18345	COG1129	ABC transporter
LAZ97_RS18350	COG1172	Belongs to the binding-protein-dependent transport system permease family
LAZ97_RS18355	COG1879	ABC-type sugar transport system periplasmic component
LAZ97_RS18360	COG3103	Sh3 type 3 domain protein
LAZ97_RS18365	COG2249	NAD(P)H dehydrogenase (quinone) activity
LAZ97_RS18370	COG3527	Alpha-acetolactate decarboxylase
LAZ97_RS18375	COG0028	Belongs to the TPP enzyme family
LAZ97_RS18380	COG0583	DNA-binding transcription factor activity
LAZ97_RS18385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LAZ97_RS18400	COG5337	Spore coat protein CotH
LAZ97_RS18410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LAZ97_RS18420	COG0405	Gamma-glutamyltransferase
LAZ97_RS18425	COG1522	sequence-specific DNA binding
LAZ97_RS18430	COG2059	Chromate
LAZ97_RS18435	COG2059	Chromate
LAZ97_RS18445	COG0655	NAD(P)H dehydrogenase (quinone) activity
LAZ97_RS18450	COG0583	DNA-binding transcription factor activity
LAZ97_RS18490	COG3878	Protein conserved in bacteria
LAZ97_RS18495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LAZ97_RS18500	COG4464	protein tyrosine phosphatase activity
LAZ97_RS18505	COG0489	protein tyrosine kinase activity
LAZ97_RS18510	COG3944	biosynthesis protein
LAZ97_RS18520	COG4715	Zinc finger, swim domain protein
LAZ97_RS18525	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LAZ97_RS18530	COG0561	phosphatase activity
LAZ97_RS18535	COG1349	DNA-binding transcription factor activity
LAZ97_RS18540	COG0629	single-stranded DNA binding
LAZ97_RS18565	COG0457	Tetratricopeptide repeat
LAZ97_RS18570	COG4786	Flagellar basal body rod
LAZ97_RS18575	COG4786	Flagellar basal body rod
LAZ97_RS18580	COG1077	Cell shape determining protein MreB Mrl
LAZ97_RS18585	COG1609	Transcriptional regulator
LAZ97_RS18590	COG1846	Transcriptional regulator
LAZ97_RS18595	COG2814	Major facilitator Superfamily
LAZ97_RS18600	COG1953	Uracil, thiamine, allantoin
LAZ97_RS18605	COG0477	Major facilitator Superfamily
LAZ97_RS18610	COG1335	isochorismatase
LAZ97_RS18615	COG0004	ammonium transporteR
LAZ97_RS18620	COG0347	Belongs to the P(II) protein family
LAZ97_RS18625	COG0772	Belongs to the SEDS family
LAZ97_RS18630	COG0671	phosphoesterase, PA-phosphatase related
LAZ97_RS18640	COG0739	heme binding
LAZ97_RS18645	COG1247	-acetyltransferase
LAZ97_RS18660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LAZ97_RS18670	COG0726	polysaccharide deacetylase
LAZ97_RS18675	COG1959	2 iron, 2 sulfur cluster binding
LAZ97_RS18690	COG0831	urea catabolic process
LAZ97_RS18700	COG1994	Peptidase M50
LAZ97_RS18705	COG0457	Tetratricopeptide repeat
LAZ97_RS18715	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LAZ97_RS18725	COG2304	oxidoreductase activity
LAZ97_RS18730	COG2304	oxidoreductase activity
LAZ97_RS18735	COG2385	sporulation resulting in formation of a cellular spore
LAZ97_RS18740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LAZ97_RS18750	COG4836	Membrane
LAZ97_RS18820	COG0698	ribose 5-phosphate isomerase
LAZ97_RS18825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LAZ97_RS18835	COG0009	L-threonylcarbamoyladenylate synthase
LAZ97_RS18840	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LAZ97_RS18860	COG2890	protein-(glutamine-N5) methyltransferase activity
LAZ97_RS18865	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LAZ97_RS18870	COG0346	lactoylglutathione lyase activity
LAZ97_RS18875	COG0789	Transcriptional regulator
LAZ97_RS18880	COG0679	Auxin Efflux Carrier
LAZ97_RS18885	COG0281	malic enzyme
LAZ97_RS18900	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LAZ97_RS18910	COG1494	fructose-1,6-bisphosphatase
LAZ97_RS18915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LAZ97_RS18925	COG0191	fructose-bisphosphate aldolase activity
LAZ97_RS18930	COG2204	response regulator
LAZ97_RS18935	COG4821	SIS domain
LAZ97_RS18950	COG2181	nitrate reductase activity
LAZ97_RS18950	COG0247	lactate metabolic process
LAZ97_RS18955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LAZ97_RS18970	COG1132	(ABC) transporter
LAZ97_RS18975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LAZ97_RS18985	COG2181	nitrate reductase activity
LAZ97_RS18990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LAZ97_RS18995	COG1140	nitrate reductase beta subunit
LAZ97_RS19000	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LAZ97_RS19005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LAZ97_RS19015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LAZ97_RS19020	COG2223	nitrite transmembrane transporter activity
LAZ97_RS19030	COG4506	Protein conserved in bacteria
LAZ97_RS19035	COG0457	Tetratricopeptide repeat
LAZ97_RS19045	COG0010	Belongs to the arginase family
LAZ97_RS19050	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LAZ97_RS19055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LAZ97_RS19070	COG1994	Peptidase M50
LAZ97_RS19075	COG1942	4-Oxalocrotonate Tautomerase
LAZ97_RS19080	COG1846	Transcriptional regulator
LAZ97_RS19085	COG0531	amino acid
LAZ97_RS19090	COG3465	dGTPase activity
LAZ97_RS19095	COG1078	dGTPase activity
LAZ97_RS19110	COG1695	Transcriptional regulator
LAZ97_RS19120	COG1131	(ABC) transporter
LAZ97_RS19125	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LAZ97_RS19155	COG0583	DNA-binding transcription factor activity
LAZ97_RS19160	COG2855	membrane
LAZ97_RS19165	COG0280	phosphate acetyltransferase
LAZ97_RS19175	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS19180	COG0436	Aminotransferase
LAZ97_RS19210	COG2814	Major facilitator Superfamily
LAZ97_RS19215	COG2814	Major facilitator Superfamily
LAZ97_RS19220	COG0833	amino acid
LAZ97_RS19225	COG4187	Peptidase family M20/M25/M40
LAZ97_RS19230	COG1012	belongs to the aldehyde dehydrogenase family
LAZ97_RS19235	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LAZ97_RS19245	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS19260	COG1131	(ABC) transporter
LAZ97_RS19265	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LAZ97_RS19270	COG1091	dTDP-4-dehydrorhamnose reductase activity
LAZ97_RS19275	COG1088	dTDP-glucose 4,6-dehydratase activity
LAZ97_RS19280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LAZ97_RS19285	COG3980	spore coat polysaccharide biosynthesis protein
LAZ97_RS19295	COG2089	acid synthase
LAZ97_RS19300	COG0456	acetyltransferase
LAZ97_RS19305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LAZ97_RS19310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LAZ97_RS19315	COG0463	Glycosyl transferase, family 2
LAZ97_RS19325	COG2363	Small membrane protein
LAZ97_RS19330	COG2233	PERMEase
LAZ97_RS19345	COG1216	Glycosyl transferase, family 2
LAZ97_RS19360	COG1695	Transcriptional regulator
LAZ97_RS19365	COG0351	phosphomethylpyrimidine kinase
LAZ97_RS19375	COG1621	beta-fructofuranosidase activity
LAZ97_RS19380	COG1263	PTS System
LAZ97_RS19380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LAZ97_RS19385	COG3711	transcriptional antiterminator
LAZ97_RS19395	COG1404	Belongs to the peptidase S8 family
LAZ97_RS19400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LAZ97_RS19405	COG0778	Nitroreductase
LAZ97_RS19410	COG0772	Belongs to the SEDS family
LAZ97_RS19415	COG0454	-acetyltransferase
LAZ97_RS19435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LAZ97_RS19440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LAZ97_RS19445	COG2261	transglycosylase associated protein
LAZ97_RS19450	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LAZ97_RS19455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LAZ97_RS19460	COG2246	polysaccharide biosynthetic process
LAZ97_RS19465	COG1309	transcriptional regulator
LAZ97_RS19485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LAZ97_RS19490	COG2837	iron assimilation
LAZ97_RS19510	COG0583	DNA-binding transcription factor activity
LAZ97_RS19520	COG1346	cytolysis
LAZ97_RS19525	COG1131	(ABC) transporter
LAZ97_RS19550	COG4895	conserved protein (DUF2196)
LAZ97_RS19560	COG5504	Zn-dependent protease
LAZ97_RS19565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LAZ97_RS19570	COG0346	lactoylglutathione lyase activity
LAZ97_RS19575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LAZ97_RS19580	COG1404	Belongs to the peptidase S8 family
LAZ97_RS19585	COG1442	glycosyl transferase family 8
LAZ97_RS19590	COG2357	RelA SpoT domain protein
LAZ97_RS19595	COG1575	Belongs to the MenA family. Type 1 subfamily
LAZ97_RS19610	COG1696	Membrane protein involved in D-alanine export
LAZ97_RS19620	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LAZ97_RS19625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LAZ97_RS19630	COG1486	melibiose metabolic process
LAZ97_RS19635	COG1447	Phosphotransferase system cellobiose-specific component IIA
LAZ97_RS19640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LAZ97_RS19645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LAZ97_RS19650	COG3711	transcriptional antiterminator
LAZ97_RS19650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LAZ97_RS19660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LAZ97_RS19665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LAZ97_RS19675	COG0640	Transcriptional regulator
LAZ97_RS19680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LAZ97_RS19685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LAZ97_RS19690	COG1447	Phosphotransferase system cellobiose-specific component IIA
LAZ97_RS19695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LAZ97_RS19700	COG2723	6-phospho-beta-galactosidase activity
LAZ97_RS19705	COG1940	carbohydrate kinase activity
LAZ97_RS19710	COG1482	cell wall glycoprotein biosynthetic process
LAZ97_RS19720	COG0753	catalase activity
LAZ97_RS19725	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LAZ97_RS19730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LAZ97_RS19735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LAZ97_RS19740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LAZ97_RS19745	COG4988	ABC transporter
LAZ97_RS19750	COG1294	oxidase, subunit
LAZ97_RS19755	COG1271	oxidase subunit
LAZ97_RS19760	COG3493	citrate carrier protein
LAZ97_RS19765	COG0726	polysaccharide deacetylase
LAZ97_RS19770	COG3842	ATPase activity
LAZ97_RS19775	COG2508	Transcriptional regulator
LAZ97_RS19780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAZ97_RS19790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LAZ97_RS19805	COG4894	glucomannan catabolic process
LAZ97_RS19810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LAZ97_RS19815	COG0500	methyltransferase
LAZ97_RS19820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LAZ97_RS19840	COG0753	catalase activity
LAZ97_RS19840	COG0693	protein deglycase activity
LAZ97_RS19845	COG2851	Citrate transporter
LAZ97_RS19850	COG2273	Hydrolase Family 16
LAZ97_RS19860	COG2270	Major facilitator Superfamily
LAZ97_RS19865	COG0513	Belongs to the DEAD box helicase family
LAZ97_RS19970	COG3209	COG3209 Rhs family protein
LAZ97_RS19980	COG0697	spore germination
LAZ97_RS19985	COG0589	response to stress
LAZ97_RS19995	COG0494	nUDIX hydrolase
LAZ97_RS20000	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LAZ97_RS20005	COG3507	Belongs to the glycosyl hydrolase 43 family
LAZ97_RS20030	COG0010	Belongs to the arginase family
LAZ97_RS20035	COG0833	amino acid
LAZ97_RS20040	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LAZ97_RS20045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LAZ97_RS20055	COG2390	Transcriptional regulator
LAZ97_RS20085	COG1131	(ABC) transporter
LAZ97_RS20095	COG0561	phosphatase activity
LAZ97_RS20125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LAZ97_RS20130	COG5294	Protein conserved in bacteria
LAZ97_RS20135	COG0577	efflux transmembrane transporter activity
LAZ97_RS20140	COG1136	(ABC) transporter
LAZ97_RS20145	COG2205	protein histidine kinase activity
LAZ97_RS20150	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS20165	COG1082	Xylose isomerase domain protein TIM barrel
LAZ97_RS20175	COG2814	Major facilitator Superfamily
LAZ97_RS20205	COG1349	DNA-binding transcription factor activity
LAZ97_RS20210	COG0667	Aldo Keto reductase
LAZ97_RS20215	COG2814	Major facilitator Superfamily
LAZ97_RS20230	COG1028	Short-chain dehydrogenase reductase Sdr
LAZ97_RS20235	COG2197	response regulator
LAZ97_RS20240	COG4585	Histidine kinase
LAZ97_RS20245	COG3239	Fatty acid desaturase
LAZ97_RS20250	COG1309	transcriptional regulator
LAZ97_RS20255	COG1012	belongs to the aldehyde dehydrogenase family
LAZ97_RS20270	COG0640	Transcriptional regulator
LAZ97_RS20275	COG2814	Major facilitator Superfamily
LAZ97_RS20280	COG1714	RDD family
LAZ97_RS20290	COG0450	alkyl hydroperoxide reductase
LAZ97_RS20295	COG3634	alkyl hydroperoxide reductase activity
LAZ97_RS20300	COG3177	Filamentation induced by cAMP protein fic
LAZ97_RS20305	COG1113	amino acid transport
LAZ97_RS20315	COG2080	2 iron, 2 sulfur cluster binding
LAZ97_RS20330	COG2068	MobA-Related Protein
LAZ97_RS20355	COG1192	Involved in chromosome partitioning
LAZ97_RS20395	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LAZ97_RS20400	COG0667	Aldo Keto reductase
LAZ97_RS20405	COG0456	acetyltransferase
LAZ97_RS20410	COG0457	Tetratricopeptide repeat
LAZ97_RS20415	COG0010	Belongs to the arginase family
LAZ97_RS20420	COG0833	amino acid
LAZ97_RS20425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LAZ97_RS20430	COG5658	integral membrane protein
LAZ97_RS20435	COG0640	Transcriptional regulator
LAZ97_RS20440	COG3829	transcription factor binding
LAZ97_RS20450	COG0488	(ABC) transporter
LAZ97_RS20465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LAZ97_RS20470	COG5002	protein histidine kinase activity
LAZ97_RS20470	COG3850	Histidine kinase
LAZ97_RS20475	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS20485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LAZ97_RS20490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LAZ97_RS20495	COG4853	Protein conserved in bacteria
LAZ97_RS20500	COG4863	YycH protein
LAZ97_RS20505	COG5002	protein histidine kinase activity
LAZ97_RS20510	COG0745	RESPONSE REGULATOR receiver
LAZ97_RS20540	COG0346	lactoylglutathione lyase activity
LAZ97_RS20545	COG0305	Participates in initiation and elongation during chromosome replication
LAZ97_RS20560	COG3093	addiction module antidote protein HigA
LAZ97_RS20565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LAZ97_RS20570	COG0297	glycogen (starch) synthase activity
LAZ97_RS20580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LAZ97_RS20585	COG0438	transferase activity, transferring glycosyl groups
LAZ97_RS20595	COG2112	serine threonine protein kinase
LAZ97_RS20605	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LAZ97_RS20610	COG4241	membrane
LAZ97_RS20620	COG5577	PFAM Coat F domain
LAZ97_RS20625	COG1733	regulation of RNA biosynthetic process
LAZ97_RS20635	COG0697	spore germination
LAZ97_RS20640	COG1621	beta-fructofuranosidase activity
LAZ97_RS20645	COG1621	beta-fructofuranosidase activity
LAZ97_RS20655	COG2318	DinB family
LAZ97_RS20660	COG2211	Major facilitator Superfamily
LAZ97_RS20670	COG0778	Nitroreductase
LAZ97_RS20675	COG1846	Transcriptional regulator
LAZ97_RS20680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAZ97_RS20685	COG1846	Transcriptional regulator
LAZ97_RS20690	COG2153	protein acetylation
LAZ97_RS20700	COG0546	phosphoglycolate phosphatase activity
LAZ97_RS20730	COG1404	Belongs to the peptidase S8 family
LAZ97_RS20740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LAZ97_RS20745	COG0697	spore germination
LAZ97_RS20780	COG1131	(ABC) transporter
LAZ97_RS20795	COG1331	Highly conserved protein containing a thioredoxin domain
LAZ97_RS20800	COG1266	CAAX protease self-immunity
LAZ97_RS20805	COG2814	Major facilitator Superfamily
LAZ97_RS20805	COG0477	Major facilitator Superfamily
LAZ97_RS20810	COG0346	lactoylglutathione lyase activity
LAZ97_RS20815	COG1609	Transcriptional regulator
LAZ97_RS20820	COG0708	Exodeoxyribonuclease III
LAZ97_RS20830	COG0708	Exodeoxyribonuclease III
LAZ97_RS20835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LAZ97_RS20840	COG2169	Transcriptional regulator
LAZ97_RS20850	COG0629	single-stranded DNA binding
LAZ97_RS20860	COG0012	GTP binding
LAZ97_RS20865	COG0243	molybdopterin cofactor binding
LAZ97_RS20870	COG4481	Protein conserved in bacteria
LAZ97_RS20875	COG3949	Membrane
LAZ97_RS20890	COG1475	DNA binding
LAZ97_RS20895	COG1192	Involved in chromosome partitioning
LAZ97_RS20920	COG1847	R3H domain protein
LAZ97_RS20925	COG0706	membrane insertase activity
LAZ97_RS20945	COG3181	Tripartite tricarboxylate transporter family receptor
LAZ97_RS21005	COG5444	nuclease activity