locus-tag	class	description
NF199_RS00010	COG0592	DNA-directed DNA polymerase activity
NF199_RS00015	COG2501	S4 domain
NF199_RS00030	COG0187	DNA topoisomerase II activity
NF199_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NF199_RS00070	COG0516	GMP reductase activity
NF199_RS00070	COG0517	IMP dehydrogenase activity
NF199_RS00075	COG1686	Belongs to the peptidase S11 family
NF199_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
NF199_RS00105	COG1428	Deoxynucleoside kinase
NF199_RS00110	COG1428	Deoxynucleoside kinase
NF199_RS00115	COG1388	LysM domain
NF199_RS00115	COG3858	chitin binding
NF199_RS00120	COG1335	isochorismatase
NF199_RS00125	COG0590	tRNA wobble adenosine to inosine editing
NF199_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NF199_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NF199_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NF199_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NF199_RS00195	COG3853	Toxic anion resistance protein (TelA)
NF199_RS00200	COG1982	Orn Lys Arg decarboxylase major
NF199_RS00210	COG3870	Protein conserved in bacteria
NF199_RS00215	COG1728	Protein conserved in bacteria
NF199_RS00220	COG0470	DNA polymerase III
NF199_RS00225	COG1774	PSP1 C-terminal conserved region
NF199_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NF199_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NF199_RS00250	COG2002	toxin-antitoxin pair type II binding
NF199_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF199_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF199_RS00260	COG0084	hydrolase, TatD family'
NF199_RS00265	COG3583	domain protein
NF199_RS00265	COG3584	3D domain protein
NF199_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NF199_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NF199_RS00285	COG4466	Protein conserved in bacteria
NF199_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NF199_RS00305	COG0251	oxidation-reduction process
NF199_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NF199_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NF199_RS00345	COG2002	toxin-antitoxin pair type II binding
NF199_RS00350	COG2244	polysaccharide biosynthetic process
NF199_RS00355	COG3956	TIGRFAM MazG family protein
NF199_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NF199_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NF199_RS00380	COG1098	S1 RNA binding domain
NF199_RS00395	COG2208	phosphoserine phosphatase activity
NF199_RS00400	COG2304	oxidoreductase activity
NF199_RS00405	COG0515	serine threonine protein kinase
NF199_RS00410	COG0037	tRNA processing
NF199_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NF199_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NF199_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NF199_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NF199_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NF199_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
NF199_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF199_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NF199_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NF199_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NF199_RS00475	COG1396	sequence-specific DNA binding
NF199_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NF199_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NF199_RS00565	COG4463	regulation of RNA biosynthetic process
NF199_RS00570	COG3880	PFAM UvrB UvrC protein
NF199_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NF199_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NF199_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
NF199_RS00615	COG1045	serine acetyltransferase
NF199_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NF199_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NF199_RS00635	COG3688	RNA-binding protein containing a PIN domain
NF199_RS00640	COG1595	DNA-templated transcription, initiation
NF199_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NF199_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
NF199_RS00680	COG2813	Specifically methylates the guanine in position
NF199_RS00695	COG1358	cellular component organization or biogenesis
NF199_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NF199_RS00830	COG0201	protein transport
NF199_RS00840	COG0024	Methionine aminopeptidase
NF199_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NF199_RS00880	COG1122	ATPase activity
NF199_RS00885	COG1122	ATPase activity
NF199_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NF199_RS00910	COG2226	methyltransferase
NF199_RS00915	COG2318	DinB family
NF199_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF199_RS00930	COG0489	protein tyrosine kinase activity
NF199_RS00940	COG2194	sulfuric ester hydrolase activity
NF199_RS00945	COG0726	polysaccharide deacetylase
NF199_RS01005	COG0738	Major facilitator superfamily
NF199_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NF199_RS01020	COG1063	alcohol dehydrogenase
NF199_RS01030	COG0385	Bile acid
NF199_RS01035	COG2819	hydrolase of the alpha beta superfamily
NF199_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF199_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF199_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF199_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF199_RS01055	COG2207	Transcriptional regulator
NF199_RS01060	COG3876	Protein conserved in bacteria
NF199_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
NF199_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF199_RS01075	COG1263	PTS System
NF199_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF199_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF199_RS01090	COG1683	Conserved Protein
NF199_RS01120	COG1595	DNA-templated transcription, initiation
NF199_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NF199_RS01135	COG4856	YbbR-like protein
NF199_RS01170	COG5002	protein histidine kinase activity
NF199_RS01175	COG1136	(ABC) transporter
NF199_RS01180	COG0577	efflux transmembrane transporter activity
NF199_RS01185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NF199_RS01200	COG1346	cytolysis
NF199_RS01205	COG1380	Effector of murein hydrolase LrgA
NF199_RS01210	COG1846	Transcriptional regulator
NF199_RS01215	COG1113	amino acid transport
NF199_RS01220	COG1011	Hydrolase
NF199_RS01225	COG4585	Histidine kinase
NF199_RS01230	COG2197	response regulator
NF199_RS01235	COG1131	(ABC) transporter
NF199_RS01275	COG0531	amino acid
NF199_RS01280	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NF199_RS01295	COG0584	glycerophosphoryl diester phosphodiesterase
NF199_RS01300	COG2271	Major facilitator Superfamily
NF199_RS01310	COG2368	4-hydroxyphenylacetate
NF199_RS01320	COG3409	Peptidoglycan-binding domain 1 protein
NF199_RS01335	COG1397	ADP-ribosylglycohydrolase
NF199_RS01340	COG5444	nuclease activity
NF199_RS01350	COG0371	Dehydrogenase
NF199_RS01360	COG1183	phosphatidylcholine synthase activity
NF199_RS01365	COG0586	Pfam SNARE associated Golgi protein
NF199_RS01370	COG0688	phosphatidylethanolamine metabolic process
NF199_RS01385	COG1301	dicarboxylic acid transport
NF199_RS01390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF199_RS01395	COG0833	amino acid
NF199_RS01400	COG2040	homocysteine
NF199_RS01405	COG1115	amino acid carrier protein
NF199_RS01410	COG2066	Belongs to the glutaminase family
NF199_RS01415	COG4191	Histidine kinase
NF199_RS01420	COG0784	Response regulator, receiver
NF199_RS01440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NF199_RS01445	COG0778	Nitroreductase
NF199_RS01450	COG0346	lactoylglutathione lyase activity
NF199_RS01455	COG2259	Doxx family
NF199_RS01460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF199_RS01475	COG3773	Cell wall hydrolase
NF199_RS01480	COG3540	Alkaline phosphatase
NF199_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NF199_RS01490	COG0805	protein transport
NF199_RS01500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NF199_RS01505	COG0477	Major facilitator Superfamily
NF199_RS01510	COG1309	transcriptional regulator
NF199_RS01515	COG0252	asparaginase activity
NF199_RS01520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NF199_RS01525	COG1405	negative regulation of cell septum assembly
NF199_RS01525	COG3012	SEC-C Motif Domain Protein
NF199_RS01540	COG1595	DNA-templated transcription, initiation
NF199_RS01545	COG1595	DNA-templated transcription, initiation
NF199_RS01550	COG1876	peptidase activity
NF199_RS01555	COG0457	Tetratricopeptide repeat
NF199_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS01565	COG0366	Alpha amylase catalytic
NF199_RS01570	COG0803	Belongs to the bacterial solute-binding protein 9 family
NF199_RS01575	COG1121	(ABC) transporter
NF199_RS01580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NF199_RS01585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF199_RS01590	COG2310	stress, protein
NF199_RS01595	COG2310	stress, protein
NF199_RS01600	COG2310	stress, protein
NF199_RS01605	COG0861	Integral membrane protein TerC family
NF199_RS01615	COG3853	Toxic anion resistance protein (TelA)
NF199_RS01620	COG0477	Major facilitator Superfamily
NF199_RS01625	COG4175	Glycine betaine
NF199_RS01625	COG0517	IMP dehydrogenase activity
NF199_RS01630	COG4176	ABC-type proline glycine betaine transport system permease component
NF199_RS01635	COG2113	Glycine betaine
NF199_RS01640	COG1473	amidohydrolase
NF199_RS01645	COG1288	antiporter activity
NF199_RS01665	COG2814	Major facilitator Superfamily
NF199_RS01670	COG1846	Transcriptional regulator
NF199_RS01675	COG1280	lysine exporter protein (LysE YggA)
NF199_RS01680	COG3403	YqcI/YcgG family
NF199_RS01685	COG1113	amino acid transport
NF199_RS01690	COG3665	Urea carboxylase-associated protein
NF199_RS01705	COG1660	Displays ATPase and GTPase activities
NF199_RS01710	COG1082	Xylose isomerase domain protein TIM barrel
NF199_RS01715	COG2271	Major facilitator Superfamily
NF199_RS01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NF199_RS01725	COG3458	cephalosporin-C deacetylase activity
NF199_RS01730	COG3541	Predicted nucleotidyltransferase
NF199_RS01735	COG0506	proline dehydrogenase activity
NF199_RS01745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF199_RS01750	COG2508	Transcriptional regulator
NF199_RS01760	COG1587	Uroporphyrinogen-III synthase
NF199_RS01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NF199_RS01765	COG2146	nitrite reductase [NAD(P)H] activity
NF199_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NF199_RS01775	COG0243	molybdopterin cofactor binding
NF199_RS01780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NF199_RS01785	COG2223	nitrite transmembrane transporter activity
NF199_RS01795	COG1063	alcohol dehydrogenase
NF199_RS01800	COG1714	RDD family
NF199_RS01820	COG3209	COG3209 Rhs family protein
NF199_RS01825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NF199_RS01830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NF199_RS01835	COG1733	regulation of RNA biosynthetic process
NF199_RS01860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS01865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS01870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS01875	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NF199_RS01890	COG2364	Membrane
NF199_RS01895	COG1126	abc transporter atp-binding protein
NF199_RS01900	COG0765	amino acid transport
NF199_RS01910	COG0583	DNA-binding transcription factor activity
NF199_RS01915	COG0163	prenyltransferase activity
NF199_RS01920	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NF199_RS01935	COG3104	oligopeptide transport
NF199_RS01940	COG5434	Belongs to the glycosyl hydrolase 28 family
NF199_RS01950	COG0697	spore germination
NF199_RS01960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NF199_RS01965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF199_RS01970	COG0456	acetyltransferase
NF199_RS01975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF199_RS01980	COG0765	amino acid transport
NF199_RS01985	COG1126	abc transporter atp-binding protein
NF199_RS01990	COG1473	amidohydrolase
NF199_RS01995	COG2079	MmgE PrpD family protein
NF199_RS02000	COG1136	(ABC) transporter
NF199_RS02005	COG0577	efflux transmembrane transporter activity
NF199_RS02010	COG0745	RESPONSE REGULATOR receiver
NF199_RS02015	COG5002	protein histidine kinase activity
NF199_RS02015	COG3850	Histidine kinase
NF199_RS02020	COG0457	Tetratricopeptide repeat
NF199_RS02035	COG0527	aspartate kinase activity
NF199_RS02040	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF199_RS02045	COG4605	iron ion homeostasis
NF199_RS02050	COG4604	ABC transporter, ATP-binding protein
NF199_RS02055	COG4607	ABC-type enterochelin transport system periplasmic component
NF199_RS02060	COG2814	Major facilitator Superfamily
NF199_RS02065	COG1309	transcriptional regulator
NF199_RS02070	COG0778	Nitroreductase
NF199_RS02075	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NF199_RS02080	COG0640	Transcriptional regulator
NF199_RS02085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF199_RS02090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NF199_RS02095	COG1012	belongs to the aldehyde dehydrogenase family
NF199_RS02100	COG4975	Glucose uptake
NF199_RS02105	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS02110	COG4549	nuclear export factor GLE1
NF199_RS02115	COG1276	copper resistance
NF199_RS02115	COG2372	response to copper ion
NF199_RS02120	COG1349	DNA-binding transcription factor activity
NF199_RS02130	COG2213	PTS system mannitol-specific
NF199_RS02135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF199_RS02145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NF199_RS02155	COG0561	phosphatase activity
NF199_RS02165	COG1914	H( )-stimulated, divalent metal cation uptake system
NF199_RS02175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NF199_RS02180	COG1984	allophanate hydrolase subunit 2
NF199_RS02185	COG1414	Transcriptional regulator
NF199_RS02190	COG2755	lipolytic protein G-D-S-L family
NF199_RS02200	COG2329	Antibiotic biosynthesis monooxygenase
NF199_RS02205	COG0768	penicillin binding
NF199_RS02210	COG4989	oxidoreductase activity
NF199_RS02220	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS02225	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS02235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF199_RS02240	COG3871	stress protein (general stress protein 26)
NF199_RS02250	COG2814	Major facilitator Superfamily
NF199_RS02255	COG1522	sequence-specific DNA binding
NF199_RS02260	COG0551	DNA topoisomerase type I activity
NF199_RS02260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NF199_RS02265	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NF199_RS02275	COG5298	Protein conserved in bacteria
NF199_RS02280	COG1215	transferase activity, transferring glycosyl groups
NF199_RS02290	COG0531	amino acid
NF199_RS02300	COG0028	Belongs to the TPP enzyme family
NF199_RS02305	COG1388	LysM domain
NF199_RS02305	COG3409	Peptidoglycan-binding domain 1 protein
NF199_RS02305	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF199_RS02325	COG0457	Tetratricopeptide repeat
NF199_RS02355	COG1914	H( )-stimulated, divalent metal cation uptake system
NF199_RS02375	COG2076	Multidrug Resistance protein
NF199_RS02380	COG2217	Heavy metal translocating P-type atpase
NF199_RS02385	COG3729	General stress protein
NF199_RS02390	COG0662	Cupin 2, conserved barrel domain protein
NF199_RS02395	COG2329	Antibiotic biosynthesis monooxygenase
NF199_RS02400	COG3546	catalase activity
NF199_RS02405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NF199_RS02410	COG3290	protein histidine kinase activity
NF199_RS02415	COG4565	transcriptional regulatory protein
NF199_RS02420	COG1301	dicarboxylic acid transport
NF199_RS02425	COG0628	permease
NF199_RS02430	COG1131	(ABC) transporter
NF199_RS02435	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NF199_RS02445	COG1960	acyl-CoA dehydrogenase activity
NF199_RS02460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NF199_RS02465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF199_RS02475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NF199_RS02480	COG0513	Belongs to the DEAD box helicase family
NF199_RS02485	COG3402	PFAM membrane-flanked domain
NF199_RS02490	COG3428	Bacterial PH domain
NF199_RS02495	COG0705	Rhomboid family
NF199_RS02505	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NF199_RS02510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NF199_RS02515	COG0864	Transcriptional regulator
NF199_RS02520	COG2337	Toxic component of a toxin-antitoxin (TA) module
NF199_RS02525	COG1366	Belongs to the anti-sigma-factor antagonist family
NF199_RS02530	COG1366	Belongs to the anti-sigma-factor antagonist family
NF199_RS02535	COG2172	sigma factor antagonist activity
NF199_RS02540	COG2208	phosphoserine phosphatase activity
NF199_RS02545	COG1366	Belongs to the anti-sigma-factor antagonist family
NF199_RS02555	COG1191	sigma factor activity
NF199_RS02560	COG2208	phosphoserine phosphatase activity
NF199_RS02565	COG2183	response to ionizing radiation
NF199_RS02630	COG5444	nuclease activity
NF199_RS02650	COG0477	Major facilitator Superfamily
NF199_RS02665	COG2030	dehydratase
NF199_RS02675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NF199_RS02680	COG1959	2 iron, 2 sulfur cluster binding
NF199_RS02685	COG2910	NAD(P)H-binding
NF199_RS02690	COG3239	Fatty acid desaturase
NF199_RS02695	COG1278	Cold shock
NF199_RS02700	COG1329	Transcriptional regulator
NF199_RS02705	COG1937	Protein conserved in bacteria
NF199_RS02710	COG2210	Belongs to the sulfur carrier protein TusA family
NF199_RS02715	COG1054	Belongs to the UPF0176 family
NF199_RS02720	COG0425	Belongs to the sulfur carrier protein TusA family
NF199_RS02720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF199_RS02730	COG0425	Belongs to the sulfur carrier protein TusA family
NF199_RS02735	COG0730	response to heat
NF199_RS02740	COG1794	racemase activity, acting on amino acids and derivatives
NF199_RS02755	COG3621	Patatin-like phospholipase
NF199_RS02765	COG0662	Cupin 2, conserved barrel domain protein
NF199_RS02780	COG0277	FAD linked oxidase domain protein
NF199_RS02805	COG0662	Cupin 2, conserved barrel domain protein
NF199_RS02810	COG2318	DinB family
NF199_RS02840	COG1064	alcohol dehydrogenase
NF199_RS02845	COG0789	Transcriptional regulator
NF199_RS02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF199_RS02865	COG2814	Major facilitator Superfamily
NF199_RS02870	COG1309	transcriptional regulator
NF199_RS02875	COG0697	spore germination
NF199_RS02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF199_RS02885	COG5577	PFAM Coat F domain
NF199_RS02895	COG1063	alcohol dehydrogenase
NF199_RS02900	COG5577	PFAM Coat F domain
NF199_RS02910	COG4585	Histidine kinase
NF199_RS02915	COG2197	response regulator
NF199_RS02920	COG2409	Drug exporters of the RND superfamily
NF199_RS02925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NF199_RS02930	COG0488	(ABC) transporter
NF199_RS02935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF199_RS02940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF199_RS02950	COG2814	Major facilitator Superfamily
NF199_RS02955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NF199_RS02965	COG0730	response to heat
NF199_RS02970	COG0456	acetyltransferase
NF199_RS02975	COG0789	Transcriptional regulator
NF199_RS02975	COG4978	Transcriptional regulator
NF199_RS02985	COG1051	belongs to the nudix hydrolase family
NF199_RS02990	COG2226	methyltransferase
NF199_RS02995	COG0473	3-isopropylmalate dehydrogenase activity
NF199_RS03000	COG1802	Transcriptional regulator
NF199_RS03005	COG1819	glycosyl
NF199_RS03020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF199_RS03030	COG1388	LysM domain
NF199_RS03035	COG2814	Major facilitator Superfamily
NF199_RS03040	COG2188	Transcriptional regulator
NF199_RS03045	COG2186	Transcriptional regulator
NF199_RS03050	COG2807	transmembrane transport
NF199_RS03055	COG2076	Multidrug Resistance protein
NF199_RS03060	COG2076	Multidrug Resistance protein
NF199_RS03065	COG1309	transcriptional regulator
NF199_RS03070	COG0531	amino acid
NF199_RS03080	COG3832	glyoxalase III activity
NF199_RS03085	COG0604	alcohol dehydrogenase
NF199_RS03090	COG2814	Major facilitator Superfamily
NF199_RS03130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NF199_RS03135	COG0802	atpase or kinase
NF199_RS03140	COG1214	PFAM Peptidase M22, glycoprotease
NF199_RS03145	COG0456	acetyltransferase
NF199_RS03150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NF199_RS03155	COG0488	(ABC) transporter
NF199_RS03170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NF199_RS03175	COG0805	protein transport
NF199_RS03185	COG1266	CAAX protease self-immunity
NF199_RS03230	COG0457	Tetratricopeptide repeat
NF199_RS03235	COG1063	alcohol dehydrogenase
NF199_RS03240	COG2211	Major facilitator Superfamily
NF199_RS03245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NF199_RS03255	COG1842	Phage shock protein A
NF199_RS03260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NF199_RS03265	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NF199_RS03270	COG4260	virion core protein, lumpy skin disease virus
NF199_RS03275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NF199_RS03275	COG2755	lipolytic protein G-D-S-L family
NF199_RS03285	COG1595	DNA-templated transcription, initiation
NF199_RS03290	COG1063	alcohol dehydrogenase
NF199_RS03295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NF199_RS03300	COG0823	Involved in the tonB-independent uptake of proteins
NF199_RS03310	COG2132	Multicopper oxidase
NF199_RS03315	COG1113	amino acid transport
NF199_RS03320	COG0714	Associated with various cellular activities
NF199_RS03325	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NF199_RS03330	COG1305	Transglutaminase-like
NF199_RS03355	COG2252	PERMEase
NF199_RS03360	COG3064	Membrane
NF199_RS03380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NF199_RS03385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NF199_RS03390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NF199_RS03395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NF199_RS03400	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NF199_RS03415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NF199_RS03425	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NF199_RS03430	COG0138	bifunctional purine biosynthesis protein purh
NF199_RS03435	COG0151	Belongs to the GarS family
NF199_RS03445	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NF199_RS03450	COG1470	cell adhesion involved in biofilm formation
NF199_RS03455	COG4496	protein, YerC YecD
NF199_RS03460	COG0069	glutamate synthase activity
NF199_RS03470	COG0210	DNA helicase
NF199_RS03480	COG4851	CamS sex pheromone cAM373 precursor
NF199_RS03485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NF199_RS03490	COG1285	pathogenesis
NF199_RS03495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF199_RS03515	COG1309	transcriptional regulator
NF199_RS03520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NF199_RS03525	COG1597	lipid kinase activity
NF199_RS03530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NF199_RS03540	COG1131	(ABC) transporter
NF199_RS03610	COG3546	catalase activity
NF199_RS03615	COG0454	-acetyltransferase
NF199_RS03625	COG2323	membrane
NF199_RS03630	COG2329	Antibiotic biosynthesis monooxygenase
NF199_RS03635	COG0346	lactoylglutathione lyase activity
NF199_RS03640	COG1366	Belongs to the anti-sigma-factor antagonist family
NF199_RS03645	COG5583	Uncharacterized small protein (DUF2292)
NF199_RS03650	COG0196	riboflavin kinase activity
NF199_RS03655	COG0670	Belongs to the BI1 family
NF199_RS03660	COG1846	Transcriptional regulator
NF199_RS03665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NF199_RS03680	COG1368	sulfuric ester hydrolase activity
NF199_RS03685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NF199_RS03690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF199_RS03695	COG1442	glycosyl transferase family 8
NF199_RS03700	COG1216	Glycosyl transferase, family 2
NF199_RS03705	COG1442	glycosyl transferase family 8
NF199_RS03710	COG2223	nitrite transmembrane transporter activity
NF199_RS03715	COG0531	amino acid
NF199_RS03720	COG1012	belongs to the aldehyde dehydrogenase family
NF199_RS03725	COG0840	transmembrane signaling receptor activity
NF199_RS03730	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS03735	COG0457	Tetratricopeptide repeat
NF199_RS03735	COG0463	Glycosyl transferase, family 2
NF199_RS03740	COG0488	(ABC) transporter
NF199_RS03745	COG0789	Transcriptional regulator
NF199_RS03750	COG2814	Major facilitator Superfamily
NF199_RS03755	COG0488	(ABC) transporter
NF199_RS03760	COG0513	Belongs to the DEAD box helicase family
NF199_RS03765	COG0456	acetyltransferase
NF199_RS03770	COG2130	NADP-dependent
NF199_RS03785	COG3866	Pectate lyase
NF199_RS03790	COG0471	metal ion transport
NF199_RS03825	COG3290	protein histidine kinase activity
NF199_RS03830	COG4565	transcriptional regulatory protein
NF199_RS03835	COG3181	Tripartite tricarboxylate transporter family receptor
NF199_RS03840	COG2851	Citrate transporter
NF199_RS03845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF199_RS03850	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NF199_RS03860	COG2258	MOSC domain
NF199_RS03880	COG0024	Methionine aminopeptidase
NF199_RS03885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF199_RS03885	COG1263	PTS System
NF199_RS03895	COG1368	sulfuric ester hydrolase activity
NF199_RS03905	COG0071	Belongs to the small heat shock protein (HSP20) family
NF199_RS03920	COG1263	PTS System
NF199_RS03920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF199_RS03925	COG0366	Alpha amylase catalytic
NF199_RS03930	COG2188	Transcriptional regulator
NF199_RS03935	COG0778	Nitroreductase
NF199_RS03950	COG0737	Belongs to the 5'-nucleotidase family
NF199_RS03955	COG0693	protein deglycase activity
NF199_RS03960	COG1609	Transcriptional regulator
NF199_RS03975	COG2814	Major facilitator Superfamily
NF199_RS03985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NF199_RS03990	COG4980	gas vesicle protein
NF199_RS03995	COG1295	ribonuclease BN
NF199_RS04000	COG0477	Major facilitator Superfamily
NF199_RS04005	COG0387	Pfam Sodium calcium exchanger
NF199_RS04015	COG0668	transmembrane transport
NF199_RS04020	COG0535	radical SAM domain protein
NF199_RS04030	COG0726	polysaccharide deacetylase
NF199_RS04050	COG0745	RESPONSE REGULATOR receiver
NF199_RS04055	COG2205	protein histidine kinase activity
NF199_RS04060	COG2084	Dehydrogenase
NF199_RS04070	COG0598	Magnesium transport protein CorA
NF199_RS04075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NF199_RS04080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NF199_RS04095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NF199_RS04100	COG4637	Psort location Cytoplasmic, score
NF199_RS04105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NF199_RS04110	COG0022	dehydrogenase e1 component
NF199_RS04115	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF199_RS04120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NF199_RS04125	COG3284	Transcriptional regulator
NF199_RS04135	COG1486	melibiose metabolic process
NF199_RS04140	COG1737	Transcriptional regulator
NF199_RS04145	COG1263	PTS System
NF199_RS04145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF199_RS04150	COG5434	Belongs to the glycosyl hydrolase 28 family
NF199_RS04155	COG5434	Belongs to the glycosyl hydrolase 28 family
NF199_RS04160	COG1132	(ABC) transporter
NF199_RS04165	COG1132	(ABC) transporter
NF199_RS04170	COG2259	Doxx family
NF199_RS04175	COG2514	catechol 2,3-dioxygenase activity
NF199_RS04190	COG1695	Transcriptional regulator
NF199_RS04195	COG2249	NAD(P)H dehydrogenase (quinone) activity
NF199_RS04200	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NF199_RS04205	COG0574	Belongs to the PEP-utilizing enzyme family
NF199_RS04205	COG3848	Pyruvate phosphate dikinase
NF199_RS04210	COG2732	(Barnase) inhibitor
NF199_RS04215	COG2318	DinB family
NF199_RS04220	COG2814	Major facilitator Superfamily
NF199_RS04225	COG1846	Transcriptional regulator
NF199_RS04230	COG0392	lysyltransferase activity
NF199_RS04230	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NF199_RS04235	COG0384	phenazine biosynthesis protein PhzF
NF199_RS04240	COG0778	Nitroreductase
NF199_RS04255	COG1090	epimerase
NF199_RS04270	COG2814	Major facilitator Superfamily
NF199_RS04280	COG3591	Belongs to the peptidase S1B family
NF199_RS04300	COG5658	integral membrane protein
NF199_RS04305	COG0596	Alpha beta hydrolase
NF199_RS04310	COG0463	Glycosyl transferase, family 2
NF199_RS04315	COG4485	Bacterial membrane protein, YfhO
NF199_RS04320	COG1988	membrane-bound metal-dependent
NF199_RS04325	COG1194	a g-specific adenine glycosylase
NF199_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS04355	COG1132	(ABC) transporter
NF199_RS04360	COG4129	membrane
NF199_RS04370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NF199_RS04375	COG0735	belongs to the Fur family
NF199_RS04490	COG3340	Belongs to the peptidase S51 family
NF199_RS04500	COG0277	FAD linked oxidase domain protein
NF199_RS04510	COG0747	negative chemotaxis
NF199_RS04515	COG0601	transmembrane transport
NF199_RS04520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF199_RS04525	COG0444	Belongs to the ABC transporter superfamily
NF199_RS04535	COG0753	catalase activity
NF199_RS04545	COG1116	anion transmembrane transporter activity
NF199_RS04555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF199_RS04575	COG1476	TRANSCRIPTIONal
NF199_RS04585	COG3382	B3 4 domain protein
NF199_RS04590	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NF199_RS04600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NF199_RS04605	COG0789	Transcriptional regulator
NF199_RS04610	COG1664	Polymer-forming cytoskeletal
NF199_RS04615	COG1664	Polymer-forming cytoskeletal
NF199_RS04620	COG2766	serine protein kinase
NF199_RS04630	COG1846	Transcriptional regulator
NF199_RS04635	COG1566	PFAM secretion protein HlyD family protein
NF199_RS04640	COG2814	Major facilitator Superfamily
NF199_RS04645	COG0655	NAD(P)H dehydrogenase (quinone) activity
NF199_RS04660	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NF199_RS04665	COG1278	Cold shock
NF199_RS04670	COG1464	Belongs to the NlpA lipoprotein family
NF199_RS04675	COG3706	GGDEF domain
NF199_RS04680	COG1823	symporter activity
NF199_RS04700	COG5577	PFAM Coat F domain
NF199_RS04705	COG4085	toxin activity
NF199_RS04705	COG0737	Belongs to the 5'-nucleotidase family
NF199_RS04705	COG1525	nuclease
NF199_RS04710	COG3764	Sortase (surface protein transpeptidase)
NF199_RS04715	COG0564	pseudouridine synthase activity
NF199_RS04725	COG0517	IMP dehydrogenase activity
NF199_RS04730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NF199_RS04735	COG3153	acetyltransferase
NF199_RS04735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NF199_RS04740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NF199_RS04745	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NF199_RS04750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NF199_RS04760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NF199_RS04765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NF199_RS04770	COG4585	Histidine kinase
NF199_RS04770	COG2203	Gaf domain
NF199_RS04775	COG2197	response regulator
NF199_RS04780	COG0431	NADPH-dependent FMN reductase
NF199_RS04800	COG1959	2 iron, 2 sulfur cluster binding
NF199_RS04810	COG2719	SpoVR family
NF199_RS04815	COG1785	Belongs to the alkaline phosphatase family
NF199_RS04820	COG1388	LysM domain
NF199_RS04820	COG0791	NLP P60 protein
NF199_RS04825	COG0583	DNA-binding transcription factor activity
NF199_RS04840	COG0531	amino acid
NF199_RS04845	COG0733	neurotransmitter:sodium symporter activity
NF199_RS04860	COG1595	DNA-templated transcription, initiation
NF199_RS04865	COG0204	Acyl-transferase
NF199_RS04870	COG1253	flavin adenine dinucleotide binding
NF199_RS04875	COG0789	Transcriptional regulator
NF199_RS04880	COG0436	Aminotransferase
NF199_RS04885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NF199_RS04890	COG1253	flavin adenine dinucleotide binding
NF199_RS04895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NF199_RS04900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NF199_RS04905	COG0584	glycerophosphoryl diester phosphodiesterase
NF199_RS04915	COG0668	transmembrane transport
NF199_RS04920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NF199_RS04925	COG0726	polysaccharide deacetylase
NF199_RS04930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF199_RS04935	COG3226	Transcriptional regulator
NF199_RS04945	COG0589	response to stress
NF199_RS04950	COG1132	(ABC) transporter
NF199_RS04955	COG0702	epimerase
NF199_RS04975	COG0189	ligase activity
NF199_RS04980	COG0189	ligase activity
NF199_RS04995	COG4335	DNA alkylation repair
NF199_RS05000	COG0561	phosphatase activity
NF199_RS05005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NF199_RS05015	COG0475	glutathione-regulated potassium exporter activity
NF199_RS05020	COG0490	domain, Protein
NF199_RS05030	COG1024	Enoyl-CoA hydratase
NF199_RS05040	COG4152	abc transporter atp-binding protein
NF199_RS05045	COG1668	transmembrane transport
NF199_RS05050	COG0420	3'-5' exonuclease activity
NF199_RS05055	COG4717	serine-type aminopeptidase activity
NF199_RS05070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NF199_RS05105	COG4980	gas vesicle protein
NF199_RS05120	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NF199_RS05125	COG0537	adenosine 5'-monophosphoramidase activity
NF199_RS05130	COG1131	(ABC) transporter
NF199_RS05135	COG4473	ABC transporter
NF199_RS05145	COG1473	amidohydrolase
NF199_RS05155	COG2329	Antibiotic biosynthesis monooxygenase
NF199_RS05160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF199_RS05170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NF199_RS05175	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NF199_RS05180	COG1309	transcriptional regulator
NF199_RS05185	COG1511	domain protein
NF199_RS05190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NF199_RS05200	COG1363	Peptidase, m42
NF199_RS05205	COG1301	dicarboxylic acid transport
NF199_RS05215	COG1234	tRNA 3'-trailer cleavage
NF199_RS05220	COG0095	Lipoate-protein ligase
NF199_RS05225	COG0702	epimerase
NF199_RS05230	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS05240	COG0501	Belongs to the peptidase M48B family
NF199_RS05245	COG1404	Belongs to the peptidase S8 family
NF199_RS05255	COG0406	alpha-ribazole phosphatase activity
NF199_RS05265	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS05270	COG1268	BioY protein
NF199_RS05280	COG0723	plastoquinol--plastocyanin reductase activity
NF199_RS05280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF199_RS05285	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS05295	COG4903	ComK protein
NF199_RS05305	COG5646	InterPro IPR014922
NF199_RS05325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF199_RS05340	COG0398	Pfam SNARE associated Golgi protein
NF199_RS05345	COG0681	Belongs to the peptidase S26 family
NF199_RS05350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NF199_RS05355	COG1846	Transcriptional regulator
NF199_RS05365	COG2814	Major facilitator Superfamily
NF199_RS05375	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NF199_RS05380	COG2323	membrane
NF199_RS05400	COG0420	3'-5' exonuclease activity
NF199_RS05405	COG0419	ATPase involved in DNA repair
NF199_RS05410	COG1403	HNH endonuclease
NF199_RS05450	COG0179	Fumarylacetoacetate (FAA) hydrolase
NF199_RS05465	COG0367	asparagine synthase
NF199_RS05475	COG0534	Mate efflux family protein
NF199_RS05490	COG2318	DinB family
NF199_RS05495	COG1279	arginine transmembrane transporter activity
NF199_RS05500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF199_RS05505	COG1357	PFAM Pentapeptide repeats (8 copies)
NF199_RS05510	COG2153	protein acetylation
NF199_RS05515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NF199_RS05515	COG0646	methionine synthase
NF199_RS05525	COG2996	Protein conserved in bacteria
NF199_RS05530	COG1744	ABC transporter substrate-binding protein PnrA-like
NF199_RS05540	COG2124	cytochrome p450
NF199_RS05550	COG1307	EDD domain protein, DegV family
NF199_RS05555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF199_RS05575	COG0561	phosphatase activity
NF199_RS05580	COG1073	alpha beta
NF199_RS05585	COG2151	metal-sulfur cluster biosynthetic enzyme
NF199_RS05595	COG0277	FAD linked oxidase domain protein
NF199_RS05600	COG2271	Major facilitator Superfamily
NF199_RS05610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NF199_RS05620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NF199_RS05625	COG0505	Belongs to the CarA family
NF199_RS05630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NF199_RS05635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NF199_RS05650	COG2267	carboxylic ester hydrolase activity
NF199_RS05660	COG1744	ABC transporter substrate-binding protein PnrA-like
NF199_RS05675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NF199_RS05680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NF199_RS05685	COG5504	Zn-dependent protease
NF199_RS05690	COG0444	Belongs to the ABC transporter superfamily
NF199_RS05695	COG4608	Belongs to the ABC transporter superfamily
NF199_RS05705	COG0601	transmembrane transport
NF199_RS05710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF199_RS05720	COG0180	Tryptophanyl-tRNA synthetase
NF199_RS05725	COG4166	transmembrane transport
NF199_RS05730	COG0601	transmembrane transport
NF199_RS05735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF199_RS05740	COG0444	Belongs to the ABC transporter superfamily
NF199_RS05745	COG4608	Belongs to the ABC transporter superfamily
NF199_RS05755	COG0456	acetyltransferase
NF199_RS05760	COG1393	Belongs to the ArsC family
NF199_RS05765	COG0861	Integral membrane protein TerC family
NF199_RS05775	COG4862	establishment of competence for transformation
NF199_RS05780	COG4469	Competence protein
NF199_RS05785	COG1164	Oligoendopeptidase f
NF199_RS05795	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NF199_RS05800	COG2346	COG2346, Truncated hemoglobins
NF199_RS05805	COG0741	lytic transglycosylase activity
NF199_RS05810	COG4116	CYTH
NF199_RS05820	COG2357	RelA SpoT domain protein
NF199_RS05825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NF199_RS05830	COG0564	pseudouridine synthase activity
NF199_RS05840	COG0475	glutathione-regulated potassium exporter activity
NF199_RS05840	COG0569	domain protein
NF199_RS05845	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NF199_RS05850	COG0352	thiamine-phosphate diphosphorylase activity
NF199_RS05855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF199_RS05860	COG2104	thiamine diphosphate biosynthetic process
NF199_RS05870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NF199_RS05875	COG0351	phosphomethylpyrimidine kinase
NF199_RS05880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NF199_RS05935	COG0210	DNA helicase
NF199_RS05955	COG1131	(ABC) transporter
NF199_RS05965	COG2153	protein acetylation
NF199_RS05975	COG2382	esterase
NF199_RS05980	COG0626	cystathionine gamma-synthase activity
NF199_RS05985	COG0626	cystathionine gamma-synthase activity
NF199_RS06015	COG5444	nuclease activity
NF199_RS06025	COG0346	lactoylglutathione lyase activity
NF199_RS06030	COG2367	Beta-lactamase
NF199_RS06035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NF199_RS06040	COG0477	Major facilitator Superfamily
NF199_RS06045	COG1846	Transcriptional regulator
NF199_RS06055	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NF199_RS06060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NF199_RS06065	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NF199_RS06070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF199_RS06070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF199_RS06075	COG1447	Phosphotransferase system cellobiose-specific component IIA
NF199_RS06085	COG1349	DNA-binding transcription factor activity
NF199_RS06105	COG1285	pathogenesis
NF199_RS06120	COG2205	protein histidine kinase activity
NF199_RS06130	COG3383	formate dehydrogenase (NAD+) activity
NF199_RS06135	COG2427	Protein of unknown function (DUF1641)
NF199_RS06140	COG2124	cytochrome p450
NF199_RS06145	COG1819	glycosyl
NF199_RS06155	COG1587	Uroporphyrinogen-III synthase
NF199_RS06160	COG0390	transport system, permease component
NF199_RS06165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NF199_RS06170	COG0697	spore germination
NF199_RS06175	COG4297	protein containing double-stranded beta helix domain
NF199_RS06185	COG1252	NADH dehydrogenase
NF199_RS06195	COG2211	Major facilitator Superfamily
NF199_RS06200	COG1609	Transcriptional regulator
NF199_RS06205	COG0246	Mannitol dehydrogenase
NF199_RS06210	COG2721	sulfolactate sulfo-lyase activity
NF199_RS06215	COG0745	RESPONSE REGULATOR receiver
NF199_RS06220	COG2205	protein histidine kinase activity
NF199_RS06220	COG2770	Histidine kinase
NF199_RS06240	COG4585	Histidine kinase
NF199_RS06245	COG2197	response regulator
NF199_RS06280	COG0730	response to heat
NF199_RS06285	COG2318	DinB family
NF199_RS06290	COG0457	Tetratricopeptide repeat
NF199_RS06300	COG3409	Peptidoglycan-binding domain 1 protein
NF199_RS06300	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF199_RS06300	COG1388	LysM domain
NF199_RS06310	COG4195	phage-related replication protein
NF199_RS06315	COG2856	Zn peptidase
NF199_RS06320	COG1396	sequence-specific DNA binding
NF199_RS06330	COG1522	sequence-specific DNA binding
NF199_RS06335	COG1484	DNA-dependent DNA replication
NF199_RS06355	COG1595	DNA-templated transcription, initiation
NF199_RS06360	COG5484	DNA packaging
NF199_RS06360	COG3728	DNA packaging
NF199_RS06365	COG1783	phage Terminase large subunit
NF199_RS06370	COG5518	Phage portal protein
NF199_RS06375	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NF199_RS06380	COG4653	Phage capsid family
NF199_RS06430	COG3953	SLT domain
NF199_RS06430	COG3953	SLT domain
NF199_RS06430	COG5412	phage tail tape measure protein
NF199_RS06430	COG5412	phage tail tape measure protein
NF199_RS06430	COG3953	SLT domain
NF199_RS06430	COG5412	phage tail tape measure protein
NF199_RS06435	COG1652	LysM domain
NF199_RS06440	COG4193	domain, Protein
NF199_RS06450	COG3628	GPW Gp25 family protein
NF199_RS06455	COG3299	homolog of phage Mu protein gp47
NF199_RS06460	COG3778	Protein conserved in bacteria
NF199_RS06500	COG3409	Peptidoglycan-binding domain 1 protein
NF199_RS06500	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF199_RS06520	COG0306	phosphate transporter
NF199_RS06525	COG1392	Phosphate transport regulator
NF199_RS06535	COG0346	lactoylglutathione lyase activity
NF199_RS06540	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NF199_RS06545	COG0463	Glycosyl transferase, family 2
NF199_RS06555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF199_RS06560	COG0477	Major facilitator Superfamily
NF199_RS06565	COG2362	D-Aminopeptidase
NF199_RS06570	COG0601	transmembrane transport
NF199_RS06575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF199_RS06585	COG4166	transmembrane transport
NF199_RS06590	COG1619	proteins homologs of microcin C7 resistance protein MccF
NF199_RS06595	COG4948	Mandelate Racemase Muconate Lactonizing
NF199_RS06600	COG0791	NLP P60 protein
NF199_RS06605	COG4608	Belongs to the ABC transporter superfamily
NF199_RS06610	COG2706	6-phosphogluconolactonase activity
NF199_RS06615	COG1834	amidinotransferase
NF199_RS06620	COG1607	acyl-coa hydrolase
NF199_RS06625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF199_RS06630	COG2076	Multidrug Resistance protein
NF199_RS06635	COG2076	Multidrug Resistance protein
NF199_RS06640	COG0788	formyltetrahydrofolate deformylase activity
NF199_RS06645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NF199_RS06655	COG1764	response to oxidative stress
NF199_RS06660	COG1846	Transcriptional regulator
NF199_RS06665	COG1764	response to oxidative stress
NF199_RS06680	COG0457	Tetratricopeptide repeat
NF199_RS06680	COG0463	Glycosyl transferase, family 2
NF199_RS06705	COG1404	Belongs to the peptidase S8 family
NF199_RS06710	COG1366	Belongs to the anti-sigma-factor antagonist family
NF199_RS06715	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NF199_RS06720	COG1122	ATPase activity
NF199_RS06725	COG4721	ABC-type cobalt transport system, permease component
NF199_RS06730	COG1388	LysM domain
NF199_RS06730	COG3858	chitin binding
NF199_RS06740	COG2239	Acts as a magnesium transporter
NF199_RS06745	COG0789	Transcriptional regulator
NF199_RS06760	COG1846	Transcriptional regulator
NF199_RS06765	COG0726	polysaccharide deacetylase
NF199_RS06770	COG1793	dna ligase
NF199_RS06770	COG3285	dna ligase
NF199_RS06775	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NF199_RS06780	COG0586	Pfam SNARE associated Golgi protein
NF199_RS06790	COG1191	sigma factor activity
NF199_RS06815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NF199_RS06820	COG2323	membrane
NF199_RS06835	COG5002	protein histidine kinase activity
NF199_RS06840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NF199_RS06860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NF199_RS06895	COG3852	Histidine kinase
NF199_RS06900	COG1846	Transcriptional regulator
NF199_RS06905	COG1360	Flagellar Motor Protein
NF199_RS06910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NF199_RS06915	COG0542	response to heat
NF199_RS06920	COG3949	Membrane
NF199_RS06935	COG0720	synthase
NF199_RS06940	COG0602	queuosine metabolic process
NF199_RS06955	COG1733	regulation of RNA biosynthetic process
NF199_RS06975	COG4873	Protein conserved in bacteria
NF199_RS06985	COG3773	Cell wall hydrolase
NF199_RS06990	COG2244	polysaccharide biosynthetic process
NF199_RS06995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF199_RS07000	COG2217	Heavy metal translocating P-type atpase
NF199_RS07005	COG0006	proline dipeptidase activity
NF199_RS07015	COG1609	Transcriptional regulator
NF199_RS07020	COG3711	transcriptional antiterminator
NF199_RS07025	COG1263	PTS System
NF199_RS07025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF199_RS07025	COG2190	(PTS) system
NF199_RS07030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF199_RS07035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NF199_RS07045	COG1533	DNA photolyase activity
NF199_RS07050	COG0840	transmembrane signaling receptor activity
NF199_RS07055	COG2084	Dehydrogenase
NF199_RS07060	COG2340	Cysteine-rich secretory protein family
NF199_RS07065	COG0768	penicillin binding
NF199_RS07070	COG4191	Histidine kinase
NF199_RS07075	COG0436	Aminotransferase
NF199_RS07085	COG0835	chemotaxis
NF199_RS07085	COG0784	Response regulator, receiver
NF199_RS07095	COG2814	Major facilitator Superfamily
NF199_RS07100	COG1376	ErfK ybiS ycfS ynhG family protein
NF199_RS07105	COG1408	metallophosphoesterase
NF199_RS07120	COG2200	EAL domain
NF199_RS07125	COG4703	Protein of unknown function (DUF1797)
NF199_RS07130	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NF199_RS07140	COG0517	IMP dehydrogenase activity
NF199_RS07145	COG0583	DNA-binding transcription factor activity
NF199_RS07150	COG0716	FMN binding
NF199_RS07160	COG0716	FMN binding
NF199_RS07180	COG0668	transmembrane transport
NF199_RS07185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF199_RS07205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NF199_RS07210	COG0303	'Molybdopterin
NF199_RS07215	COG1763	Mo-molybdopterin cofactor biosynthetic process
NF199_RS07220	COG0314	molybdopterin synthase activity
NF199_RS07225	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NF199_RS07235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NF199_RS07240	COG1136	(ABC) transporter
NF199_RS07245	COG0577	efflux transmembrane transporter activity
NF199_RS07250	COG1349	DNA-binding transcription factor activity
NF199_RS07255	COG1105	Belongs to the carbohydrate kinase PfkB family
NF199_RS07260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF199_RS07260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF199_RS07260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF199_RS07265	COG0681	Belongs to the peptidase S26 family
NF199_RS07275	COG0488	(ABC) transporter
NF199_RS07280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NF199_RS07285	COG2309	aminopeptidase activity
NF199_RS07300	COG2002	toxin-antitoxin pair type II binding
NF199_RS07305	COG3852	Histidine kinase
NF199_RS07310	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NF199_RS07310	COG2105	PFAM AIG2 family protein
NF199_RS07315	COG0569	domain protein
NF199_RS07325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NF199_RS07335	COG0561	phosphatase activity
NF199_RS07340	COG0242	peptide deformylase activity
NF199_RS07350	COG0497	DNA recombination
NF199_RS07355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NF199_RS07355	COG2070	2-Nitropropane dioxygenase
NF199_RS07360	COG3321	synthase
NF199_RS07360	COG4221	oxidoreductase activity
NF199_RS07360	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS07360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS07365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS07365	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS07365	COG3321	synthase
NF199_RS07365	COG4221	oxidoreductase activity
NF199_RS07370	COG3321	synthase
NF199_RS07370	COG0300	oxidoreductase activity
NF199_RS07370	COG4221	oxidoreductase activity
NF199_RS07370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS07380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS07380	COG4221	oxidoreductase activity
NF199_RS07380	COG3321	synthase
NF199_RS07380	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS07385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS07385	COG0300	oxidoreductase activity
NF199_RS07385	COG3321	synthase
NF199_RS07385	COG4221	oxidoreductase activity
NF199_RS07390	COG4221	oxidoreductase activity
NF199_RS07390	COG0300	oxidoreductase activity
NF199_RS07390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS07390	COG3321	synthase
NF199_RS07395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS07395	COG0300	oxidoreductase activity
NF199_RS07395	COG3321	synthase
NF199_RS07395	COG4221	oxidoreductase activity
NF199_RS07400	COG4221	oxidoreductase activity
NF199_RS07400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS07400	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS07400	COG3321	synthase
NF199_RS07405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF199_RS07410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NF199_RS07415	COG0022	dehydrogenase e1 component
NF199_RS07420	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF199_RS07425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NF199_RS07430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF199_RS07445	COG1982	Orn Lys Arg decarboxylase major
NF199_RS07465	COG0483	inositol monophosphate 1-phosphatase activity
NF199_RS07475	COG3227	Zinc metalloprotease (Elastase)
NF199_RS07480	COG1595	DNA-templated transcription, initiation
NF199_RS07510	COG4896	Protein conserved in bacteria
NF199_RS07520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NF199_RS07525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NF199_RS07530	COG2066	Belongs to the glutaminase family
NF199_RS07540	COG0772	Belongs to the SEDS family
NF199_RS07545	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NF199_RS07560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NF199_RS07560	COG2010	Cytochrome c
NF199_RS07565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NF199_RS07570	COG1845	cytochrome c oxidase, subunit III
NF199_RS07575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NF199_RS07580	COG3336	cytochrome c oxidase
NF199_RS07590	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NF199_RS07595	COG2340	Cysteine-rich secretory protein family
NF199_RS07610	COG3679	Belongs to the UPF0342 family
NF199_RS07620	COG0742	ribosomal rna small subunit methyltransferase
NF199_RS07630	COG3314	Sporulation integral membrane protein YlbJ
NF199_RS07635	COG1752	Esterase of the alpha-beta hydrolase superfamily
NF199_RS07640	COG3480	Lon protease (S16) C-terminal proteolytic domain
NF199_RS07650	COG1399	metal-binding, possibly nucleic acid-binding protein
NF199_RS07670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NF199_RS07690	COG4839	cell division protein FtsL
NF199_RS07700	COG0768	penicillin binding
NF199_RS07720	COG0772	Belongs to the SEDS family
NF199_RS07735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NF199_RS07740	COG0849	cell division
NF199_RS07745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NF199_RS07750	COG1404	Belongs to the peptidase S8 family
NF199_RS07750	COG4412	M6 family metalloprotease domain protein
NF199_RS07760	COG1191	sigma factor activity
NF199_RS07765	COG1191	sigma factor activity
NF199_RS07770	COG1119	ATPase activity
NF199_RS07775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF199_RS07780	COG1873	PFAM PRC-barrel domain
NF199_RS07785	COG1496	oxidoreductase activity
NF199_RS07790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NF199_RS07800	COG0762	integral membrane protein
NF199_RS07805	COG2302	S4 RNA-binding domain
NF199_RS07810	COG3599	regulation of cell shape
NF199_RS07820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NF199_RS07830	COG0564	pseudouridine synthase activity
NF199_RS07840	COG2233	PERMEase
NF199_RS07850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NF199_RS07855	COG0505	Belongs to the CarA family
NF199_RS07860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NF199_RS07875	COG0284	orotidine-5'-phosphate decarboxylase activity
NF199_RS07880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NF199_RS07890	COG0306	phosphate transporter
NF199_RS07905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NF199_RS07910	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NF199_RS07915	COG1648	precorrin-2 dehydrogenase activity
NF199_RS07925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NF199_RS07940	COG0194	GDP metabolic process
NF199_RS07950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NF199_RS07955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NF199_RS07960	COG0242	peptide deformylase activity
NF199_RS07970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NF199_RS07970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NF199_RS07980	COG0631	protein serine/threonine phosphatase activity
NF199_RS07985	COG2815	serine threonine protein kinase
NF199_RS07985	COG0515	serine threonine protein kinase
NF199_RS07995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NF199_RS08000	COG1564	THIamine pyrophosphokinase
NF199_RS08015	COG1302	Protein conserved in bacteria
NF199_RS08025	COG1760	l-serine dehydratase
NF199_RS08030	COG1760	l-serine dehydratase
NF199_RS08035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NF199_RS08050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NF199_RS08055	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS08075	COG0552	protein localization to endoplasmic reticulum
NF199_RS08090	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NF199_RS08100	COG1837	Belongs to the UPF0109 family
NF199_RS08125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NF199_RS08140	COG2257	FlhB HrpN YscU SpaS Family
NF199_RS08150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NF199_RS08155	COG0758	DNA mediated transformation
NF199_RS08160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NF199_RS08170	COG4974	Belongs to the 'phage' integrase family
NF199_RS08190	COG1815	bacterial-type flagellum-dependent cell motility
NF199_RS08195	COG1558	bacterial-type flagellum-dependent cell motility
NF199_RS08200	COG1677	Flagellar hook-basal body complex protein FliE
NF199_RS08205	COG1766	The M ring may be actively involved in energy transduction
NF199_RS08210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NF199_RS08215	COG1317	bacterial-type flagellum organization
NF199_RS08220	COG1157	protein secretion by the type III secretion system
NF199_RS08225	COG2882	bacterial-type flagellum organization
NF199_RS08230	COG3334	PFAM MgtE intracellular
NF199_RS08240	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NF199_RS08245	COG4786	Flagellar basal body rod
NF199_RS08250	COG1582	Flagellar protein (FlbD)
NF199_RS08255	COG1580	Controls the rotational direction of flagella during chemotaxis
NF199_RS08260	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NF199_RS08265	COG1776	CheC inhibitor of MCP methylation
NF199_RS08265	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NF199_RS08270	COG2201	protein-glutamate methylesterase activity
NF199_RS08275	COG3190	flagellar
NF199_RS08280	COG1338	Plays a role in the flagellum-specific transport system
NF199_RS08285	COG1987	bacterial-type flagellum assembly
NF199_RS08290	COG1684	flagellar biosynthetic protein fliR
NF199_RS08295	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NF199_RS08300	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NF199_RS08305	COG1419	protein localization to endoplasmic reticulum
NF199_RS08310	COG0455	bacterial-type flagellum organization
NF199_RS08315	COG2201	protein-glutamate methylesterase activity
NF199_RS08320	COG0643	Histidine kinase
NF199_RS08320	COG2198	Histidine kinase
NF199_RS08325	COG0835	chemotaxis
NF199_RS08330	COG1776	CheC inhibitor of MCP methylation
NF199_RS08340	COG1191	sigma factor activity
NF199_RS08370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NF199_RS08375	COG4589	Belongs to the CDS family
NF199_RS08385	COG0750	zinc metalloprotease
NF199_RS08405	COG0195	Participates in both transcription termination and antitermination
NF199_RS08410	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NF199_RS08415	COG1358	cellular component organization or biogenesis
NF199_RS08425	COG1550	Protein conserved in bacteria
NF199_RS08440	COG0196	riboflavin kinase activity
NF199_RS08455	COG0726	polysaccharide deacetylase
NF199_RS08460	COG0612	Peptidase, M16
NF199_RS08465	COG1873	PFAM PRC-barrel domain
NF199_RS08470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NF199_RS08475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NF199_RS08480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NF199_RS08485	COG0527	aspartate kinase activity
NF199_RS08495	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NF199_RS08500	COG0740	serine-type endopeptidase activity
NF199_RS08510	COG1674	ftsk spoiiie
NF199_RS08510	COG4980	gas vesicle protein
NF199_RS08515	COG2188	Transcriptional regulator
NF199_RS08520	COG2814	Major facilitator Superfamily
NF199_RS08525	COG1846	Transcriptional regulator
NF199_RS08535	COG0612	Peptidase, M16
NF199_RS08540	COG0612	Peptidase, M16
NF199_RS08545	COG0300	oxidoreductase activity
NF199_RS08560	COG1426	Protein conserved in bacteria
NF199_RS08565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NF199_RS08590	COG1692	metallophosphoesterase
NF199_RS08595	COG2359	stage V sporulation protein S
NF199_RS08615	COG4550	Control of competence regulator ComK, YlbF/YmcA
NF199_RS08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS08665	COG3425	synthase
NF199_RS08670	COG1024	Enoyl-CoA hydratase
NF199_RS08675	COG1024	Enoyl-CoA hydratase
NF199_RS08685	COG0300	oxidoreductase activity
NF199_RS08685	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS08685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS08685	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS08685	COG3321	synthase
NF199_RS08690	COG4221	oxidoreductase activity
NF199_RS08690	COG3321	synthase
NF199_RS08690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS08690	COG0300	oxidoreductase activity
NF199_RS08695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS08695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF199_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS08695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS08695	COG3321	synthase
NF199_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS08695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS08695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS08695	COG3321	synthase
NF199_RS08695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF199_RS08700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS08700	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS08700	COG4221	oxidoreductase activity
NF199_RS08700	COG3321	synthase
NF199_RS08705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS08705	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NF199_RS08705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NF199_RS08705	COG3321	synthase
NF199_RS08710	COG2124	cytochrome p450
NF199_RS08715	COG3209	COG3209 Rhs family protein
NF199_RS08720	COG3619	membrane
NF199_RS08730	COG1404	Belongs to the peptidase S8 family
NF199_RS08740	COG4195	phage-related replication protein
NF199_RS08745	COG1764	response to oxidative stress
NF199_RS08755	COG2076	Multidrug Resistance protein
NF199_RS08795	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF199_RS08800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF199_RS08805	COG4112	unkown
NF199_RS08815	COG0464	growth
NF199_RS08820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NF199_RS08825	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NF199_RS08830	COG0789	Transcriptional regulator
NF199_RS08835	COG0174	glutamine synthetase
NF199_RS08880	COG2211	Major facilitator Superfamily
NF199_RS08885	COG3507	Belongs to the glycosyl hydrolase 43 family
NF199_RS08900	COG1070	Carbohydrate kinase
NF199_RS08925	COG2318	DinB family
NF199_RS08930	COG1064	alcohol dehydrogenase
NF199_RS08935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NF199_RS08935	COG4451	ribulose bisphosphate carboxylase, small
NF199_RS08980	COG3397	chitin binding
NF199_RS09000	COG5434	Belongs to the glycosyl hydrolase 28 family
NF199_RS09005	COG0756	dUTP diphosphatase activity
NF199_RS09015	COG4195	phage-related replication protein
NF199_RS09050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NF199_RS09080	COG0785	Cytochrome C biogenesis protein
NF199_RS09085	COG2201	protein-glutamate methylesterase activity
NF199_RS09090	COG4846	Membrane protein involved in cytochrome C biogenesis
NF199_RS09100	COG0071	Belongs to the small heat shock protein (HSP20) family
NF199_RS09115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NF199_RS09120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF199_RS09140	COG0824	Thioesterase
NF199_RS09150	COG4841	protein insertion into membrane
NF199_RS09160	COG1832	CoA-binding protein
NF199_RS09165	COG0187	DNA topoisomerase II activity
NF199_RS09170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NF199_RS09185	COG1115	amino acid carrier protein
NF199_RS09195	COG1063	alcohol dehydrogenase
NF199_RS09200	COG0800	Aldolase
NF199_RS09210	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS09215	COG1609	Transcriptional regulator
NF199_RS09220	COG2271	Major facilitator Superfamily
NF199_RS09265	COG2205	protein histidine kinase activity
NF199_RS09270	COG0745	RESPONSE REGULATOR receiver
NF199_RS09280	COG3507	Belongs to the glycosyl hydrolase 43 family
NF199_RS09305	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS09310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NF199_RS09320	COG2610	gluconate transmembrane transporter activity
NF199_RS09325	COG2124	cytochrome p450
NF199_RS09345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NF199_RS09355	COG2246	polysaccharide biosynthetic process
NF199_RS09365	COG0586	Pfam SNARE associated Golgi protein
NF199_RS09370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NF199_RS09375	COG1024	Enoyl-CoA hydratase
NF199_RS09380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NF199_RS09385	COG0511	ligase activity, forming carbon-carbon bonds
NF199_RS09390	COG0439	Biotin carboxylase
NF199_RS09395	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS09400	COG1960	acyl-CoA dehydrogenase activity
NF199_RS09405	COG1649	PFAM Uncharacterised BCR, COG1649
NF199_RS09415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS09415	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NF199_RS09420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS09430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS09440	COG2027	D-alanyl-D-alanine carboxypeptidase
NF199_RS09445	COG2017	converts alpha-aldose to the beta-anomer
NF199_RS09450	COG0534	Mate efflux family protein
NF199_RS09465	COG0582	viral genome integration into host DNA
NF199_RS09470	COG0166	Belongs to the GPI family
NF199_RS09475	COG0405	Gamma-glutamyltransferase
NF199_RS09480	COG2814	Major facilitator Superfamily
NF199_RS09485	COG0640	Transcriptional regulator
NF199_RS09490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NF199_RS09500	COG0604	alcohol dehydrogenase
NF199_RS09505	COG0493	'glutamate synthase
NF199_RS09510	COG0069	glutamate synthase activity
NF199_RS09510	COG0067	glutamate synthase
NF199_RS09510	COG0070	glutamate synthase
NF199_RS09515	COG0583	DNA-binding transcription factor activity
NF199_RS09520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NF199_RS09535	COG0300	oxidoreductase activity
NF199_RS09540	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NF199_RS09555	COG1070	Carbohydrate kinase
NF199_RS09560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NF199_RS09595	COG5444	nuclease activity
NF199_RS09600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF199_RS09605	COG2207	Transcriptional regulator
NF199_RS09605	COG0662	Cupin 2, conserved barrel domain protein
NF199_RS09610	COG1309	transcriptional regulator
NF199_RS09615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF199_RS09625	COG0640	Transcriptional regulator
NF199_RS09630	COG0741	lytic transglycosylase activity
NF199_RS09635	COG2322	membrane
NF199_RS09650	COG1619	proteins homologs of microcin C7 resistance protein MccF
NF199_RS09660	COG3584	3D domain protein
NF199_RS09660	COG1388	LysM domain
NF199_RS09665	COG0514	ATP-dependent DNA helicase (RecQ)
NF199_RS09675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NF199_RS09680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NF199_RS09695	COG0071	Belongs to the small heat shock protein (HSP20) family
NF199_RS09725	COG1012	belongs to the aldehyde dehydrogenase family
NF199_RS09735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NF199_RS09740	COG0733	neurotransmitter:sodium symporter activity
NF199_RS09745	COG0385	Bile acid
NF199_RS09750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF199_RS09755	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF199_RS09765	COG4548	von Willebrand factor, type A
NF199_RS09770	COG0714	Associated with various cellular activities
NF199_RS09780	COG0791	NLP P60 protein
NF199_RS09780	COG1388	LysM domain
NF199_RS09785	COG1819	glycosyl
NF199_RS09790	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NF199_RS09795	COG0534	Mate efflux family protein
NF199_RS09800	COG1366	Belongs to the anti-sigma-factor antagonist family
NF199_RS09805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NF199_RS09810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NF199_RS09820	COG2962	Rard protein
NF199_RS09835	COG1942	4-Oxalocrotonate Tautomerase
NF199_RS09845	COG1733	regulation of RNA biosynthetic process
NF199_RS09850	COG0778	Nitroreductase
NF199_RS09855	COG0400	carboxylic ester hydrolase activity
NF199_RS09860	COG0346	lactoylglutathione lyase activity
NF199_RS09870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF199_RS09880	COG2723	6-phospho-beta-galactosidase activity
NF199_RS09890	COG3409	Peptidoglycan-binding domain 1 protein
NF199_RS09890	COG0793	Belongs to the peptidase S41A family
NF199_RS09895	COG2226	methyltransferase
NF199_RS09905	COG1876	peptidase activity
NF199_RS09925	COG0671	phosphoesterase, PA-phosphatase related
NF199_RS09955	COG1509	lysine 2,3-aminomutase activity
NF199_RS09960	COG0456	acetyltransferase
NF199_RS09965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF199_RS09970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NF199_RS09975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NF199_RS09980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NF199_RS09985	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NF199_RS09995	COG0456	acetyltransferase
NF199_RS10000	COG0463	Glycosyl transferase, family 2
NF199_RS10015	COG4641	Protein conserved in bacteria
NF199_RS10025	COG1086	Polysaccharide biosynthesis protein
NF199_RS10060	COG0457	Tetratricopeptide repeat
NF199_RS10070	COG3391	amine dehydrogenase activity
NF199_RS10090	COG5444	nuclease activity
NF199_RS10095	COG4282	regulation of fungal-type cell wall biogenesis
NF199_RS10100	COG1525	nuclease
NF199_RS10125	COG1846	Transcriptional regulator
NF199_RS10130	COG4698	Protein conserved in bacteria
NF199_RS10135	COG2755	lipolytic protein G-D-S-L family
NF199_RS10140	COG1999	signal sequence binding
NF199_RS10150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NF199_RS10155	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NF199_RS10160	COG1272	protein, Hemolysin III
NF199_RS10165	COG0204	Acyl-transferase
NF199_RS10170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NF199_RS10185	COG2521	methyltransferase
NF199_RS10185	COG2136	Putative SAM-dependent methyltransferase
NF199_RS10200	COG1413	lyase activity
NF199_RS10205	COG1418	mRNA catabolic process
NF199_RS10210	COG0386	Belongs to the glutathione peroxidase family
NF199_RS10220	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NF199_RS10230	COG1278	Cold shock
NF199_RS10250	COG0328	RNA-DNA hybrid ribonuclease activity
NF199_RS10255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NF199_RS10260	COG0328	RNA-DNA hybrid ribonuclease activity
NF199_RS10270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF199_RS10295	COG1755	Isoprenylcysteine carboxyl methyltransferase
NF199_RS10300	COG3424	synthase
NF199_RS10325	COG1335	isochorismatase
NF199_RS10335	COG2233	PERMEase
NF199_RS10345	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NF199_RS10350	COG1199	ATP-dependent helicase activity
NF199_RS10365	COG0116	Belongs to the methyltransferase superfamily
NF199_RS10395	COG3359	exonuclease
NF199_RS10400	COG1205	dead DEAH box helicase
NF199_RS10400	COG1111	helicase
NF199_RS10405	COG2190	(PTS) system
NF199_RS10410	COG0071	Belongs to the small heat shock protein (HSP20) family
NF199_RS10450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF199_RS10450	COG4499	WXG100 protein secretion system (Wss), protein YukC
NF199_RS10460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NF199_RS10465	COG3935	DnaD domain protein
NF199_RS10475	COG0436	Aminotransferase
NF199_RS10480	COG5353	protein conserved in bacteria
NF199_RS10490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NF199_RS10490	COG1199	ATP-dependent helicase activity
NF199_RS10520	COG0438	transferase activity, transferring glycosyl groups
NF199_RS10525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NF199_RS10540	COG1694	Mazg nucleotide pyrophosphohydrolase
NF199_RS10545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF199_RS10560	COG4347	Protein of unknown function (DUF1405)
NF199_RS10565	COG2010	Cytochrome c
NF199_RS10565	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NF199_RS10570	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NF199_RS10575	COG0723	plastoquinol--plastocyanin reductase activity
NF199_RS10590	COG0457	Tetratricopeptide repeat
NF199_RS10600	COG0287	Prephenate dehydrogenase
NF199_RS10635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NF199_RS10640	COG4401	Chorismate mutase type I
NF199_RS10655	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NF199_RS10660	COG0105	UTP biosynthetic process
NF199_RS10665	COG0142	geranyltranstransferase activity
NF199_RS10675	COG0142	geranyltranstransferase activity
NF199_RS10690	COG0776	regulation of translation
NF199_RS10695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NF199_RS10735	COG0539	negative regulation of cytoplasmic translation
NF199_RS10750	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NF199_RS10755	COG2959	enzyme of heme biosynthesis
NF199_RS10760	COG3773	Cell wall hydrolase
NF199_RS10760	COG3409	Peptidoglycan-binding domain 1 protein
NF199_RS10765	COG2339	peptidase activity
NF199_RS10770	COG0492	ferredoxin-NADP+ reductase activity
NF199_RS10775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NF199_RS10780	COG4862	establishment of competence for transformation
NF199_RS10785	COG1408	metallophosphoesterase
NF199_RS10795	COG1388	LysM domain
NF199_RS10800	COG1266	CAAX protease self-immunity
NF199_RS10810	COG4955	Helix-turn-helix domain
NF199_RS10815	COG1141	Ferredoxin
NF199_RS10820	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NF199_RS10825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NF199_RS10835	COG1595	DNA-templated transcription, initiation
NF199_RS10840	COG5002	protein histidine kinase activity
NF199_RS10845	COG0745	RESPONSE REGULATOR receiver
NF199_RS10850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NF199_RS10855	COG1333	cytochrome c biogenesis protein
NF199_RS10860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF199_RS10865	COG1187	pseudouridine synthase activity
NF199_RS10870	COG0700	Nucleoside recognition
NF199_RS10875	COG2715	membrane protein required for spore maturation
NF199_RS10880	COG1686	Belongs to the peptidase S11 family
NF199_RS10905	COG1547	Domain of unknown function (DUF309)
NF199_RS10910	COG0456	acetyltransferase
NF199_RS10925	COG0307	riboflavin synthase, alpha
NF199_RS10930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NF199_RS10930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NF199_RS10940	COG0681	Belongs to the peptidase S26 family
NF199_RS10950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NF199_RS10955	COG4086	secreted protein
NF199_RS10960	COG0019	diaminopimelate decarboxylase activity
NF199_RS10965	COG0697	spore germination
NF199_RS10980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NF199_RS11000	COG1191	sigma factor activity
NF199_RS11010	COG1366	Belongs to the anti-sigma-factor antagonist family
NF199_RS11015	COG1686	Belongs to the peptidase S11 family
NF199_RS11020	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NF199_RS11025	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NF199_RS11030	COG4974	Belongs to the 'phage' integrase family
NF199_RS11040	COG0735	belongs to the Fur family
NF199_RS11045	COG1300	Membrane
NF199_RS11060	COG0281	malic enzyme
NF199_RS11065	COG1757	Na H antiporter
NF199_RS11070	COG1027	Aspartate ammonia-lyase
NF199_RS11075	COG0252	asparaginase activity
NF199_RS11080	COG1396	sequence-specific DNA binding
NF199_RS11085	COG1379	DNA repair
NF199_RS11090	COG0494	nUDIX hydrolase
NF199_RS11100	COG0667	Aldo Keto reductase
NF199_RS11110	COG1073	alpha beta
NF199_RS11120	COG4918	Iron-sulphur cluster biosynthesis
NF199_RS11125	COG0456	acetyltransferase
NF199_RS11125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NF199_RS11130	COG2329	Antibiotic biosynthesis monooxygenase
NF199_RS11135	COG0456	acetyltransferase
NF199_RS11140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NF199_RS11155	COG0628	permease
NF199_RS11165	COG0346	lactoylglutathione lyase activity
NF199_RS11175	COG3048	D-serine ammonia-lyase activity
NF199_RS11180	COG0300	oxidoreductase activity
NF199_RS11185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF199_RS11190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NF199_RS11195	COG1024	Enoyl-CoA hydratase
NF199_RS11200	COG3425	synthase
NF199_RS11205	COG2124	cytochrome p450
NF199_RS11210	COG3321	synthase
NF199_RS11210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF199_RS11210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS11210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS11215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS11215	COG3321	synthase
NF199_RS11215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF199_RS11215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS11220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS11220	COG0300	oxidoreductase activity
NF199_RS11220	COG3321	synthase
NF199_RS11220	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS11225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS11225	COG0300	oxidoreductase activity
NF199_RS11225	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS11225	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS11225	COG3321	synthase
NF199_RS11230	COG3321	synthase
NF199_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS11230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS11230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF199_RS11230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS11235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS11235	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS11235	COG3321	synthase
NF199_RS11235	COG0300	oxidoreductase activity
NF199_RS11240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS11240	COG0300	oxidoreductase activity
NF199_RS11240	COG3321	synthase
NF199_RS11240	COG4221	oxidoreductase activity
NF199_RS11245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF199_RS11245	COG3321	synthase
NF199_RS11245	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS11245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF199_RS11245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF199_RS11250	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS11255	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS11270	COG2070	2-Nitropropane dioxygenase
NF199_RS11270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NF199_RS11275	COG0250	Participates in transcription elongation, termination and antitermination
NF199_RS11295	COG0596	Alpha beta hydrolase
NF199_RS11310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NF199_RS11315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NF199_RS11330	COG0706	membrane insertase activity
NF199_RS11335	COG2195	Cleaves the N-terminal amino acid of tripeptides
NF199_RS11340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NF199_RS11345	COG0346	lactoylglutathione lyase activity
NF199_RS11360	COG4129	membrane
NF199_RS11365	COG1126	abc transporter atp-binding protein
NF199_RS11370	COG0765	amino acid transport
NF199_RS11375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF199_RS11385	COG1597	lipid kinase activity
NF199_RS11390	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF199_RS11395	COG0022	dehydrogenase e1 component
NF199_RS11400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NF199_RS11405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NF199_RS11410	COG3426	butyrate kinase activity
NF199_RS11415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NF199_RS11420	COG0280	phosphate acetyltransferase
NF199_RS11425	COG3290	protein histidine kinase activity
NF199_RS11425	COG3829	transcription factor binding
NF199_RS11435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NF199_RS11440	COG2079	MmgE PrpD family protein
NF199_RS11445	COG0372	Belongs to the citrate synthase family
NF199_RS11450	COG1960	acyl-CoA dehydrogenase activity
NF199_RS11455	COG1250	3-hydroxyacyl-CoA dehydrogenase
NF199_RS11465	COG0584	glycerophosphoryl diester phosphodiesterase
NF199_RS11470	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF199_RS11495	COG1902	pentaerythritol trinitrate reductase activity
NF199_RS11510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NF199_RS11515	COG0745	RESPONSE REGULATOR receiver
NF199_RS11520	COG0750	zinc metalloprotease
NF199_RS11525	COG0497	DNA recombination
NF199_RS11535	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NF199_RS11545	COG0142	geranyltranstransferase activity
NF199_RS11555	COG1570	exodeoxyribonuclease VII activity
NF199_RS11570	COG1302	Protein conserved in bacteria
NF199_RS11575	COG0439	Biotin carboxylase
NF199_RS11580	COG0511	ligase activity, forming carbon-carbon bonds
NF199_RS11620	COG3854	ATPases associated with a variety of cellular activities
NF199_RS11635	COG0006	proline dipeptidase activity
NF199_RS11645	COG3872	metal-dependent enzyme
NF199_RS11655	COG1752	Esterase of the alpha-beta hydrolase superfamily
NF199_RS11670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF199_RS11690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NF199_RS11705	COG1396	sequence-specific DNA binding
NF199_RS11715	COG0681	Belongs to the peptidase S26 family
NF199_RS11740	COG4940	Competence protein ComGF
NF199_RS11750	COG4970	Tfp pilus assembly protein FimT
NF199_RS11755	COG4537	Required for transformation and DNA binding
NF199_RS11760	COG1459	type II secretion system
NF199_RS11765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NF199_RS11770	COG0598	Magnesium transport protein CorA
NF199_RS11775	COG1253	flavin adenine dinucleotide binding
NF199_RS11780	COG1366	Belongs to the anti-sigma-factor antagonist family
NF199_RS11790	COG1393	Belongs to the ArsC family
NF199_RS11800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF199_RS11810	COG0011	TIGRFAM Protein of
NF199_RS11820	COG2866	Carboxypeptidase
NF199_RS11825	COG1940	carbohydrate kinase activity
NF199_RS11830	COG4483	Protein conserved in bacteria
NF199_RS11835	COG1757	Na H antiporter
NF199_RS11845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NF199_RS11860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NF199_RS11865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NF199_RS11870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NF199_RS11875	COG0581	inorganic phosphate transmembrane transporter activity
NF199_RS11880	COG0573	inorganic phosphate transmembrane transporter activity
NF199_RS11885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NF199_RS11890	COG0768	penicillin binding
NF199_RS11895	COG0477	Major facilitator Superfamily
NF199_RS11900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NF199_RS11905	COG2839	Protein conserved in bacteria
NF199_RS11910	COG5521	maltodextrose utilization protein MalA
NF199_RS11915	COG1388	LysM domain
NF199_RS11925	COG4709	membrane
NF199_RS11930	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NF199_RS11935	COG0735	belongs to the Fur family
NF199_RS11940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF199_RS11955	COG0513	Belongs to the DEAD box helicase family
NF199_RS11970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NF199_RS11975	COG2384	SAM-dependent methyltransferase
NF199_RS11980	COG2010	Cytochrome c
NF199_RS11985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NF199_RS11990	COG0358	DNA primase activity
NF199_RS12005	COG0517	IMP dehydrogenase activity
NF199_RS12010	COG0751	glycine-tRNA ligase activity
NF199_RS12030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NF199_RS12035	COG0295	cytidine deaminase activity
NF199_RS12040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NF199_RS12050	COG1480	7TM receptor with intracellular HD hydrolase
NF199_RS12055	COG1702	phosphate starvation-inducible protein PhoH
NF199_RS12060	COG0561	phosphatase activity
NF199_RS12075	COG4864	UPF0365 protein
NF199_RS12080	COG1030	water channel activity
NF199_RS12085	COG1610	YqeY-like protein
NF199_RS12095	COG1283	sodium-dependent phosphate transmembrane transporter activity
NF199_RS12100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NF199_RS12105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NF199_RS12135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NF199_RS12150	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF199_RS12185	COG2131	deaminase
NF199_RS12190	COG1555	photosystem II stabilization
NF199_RS12190	COG1596	polysaccharide export
NF199_RS12195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NF199_RS12200	COG2226	methyltransferase
NF199_RS12205	COG0799	negative regulation of ribosome biogenesis
NF199_RS12210	COG1713	HD superfamily hydrolase involved in NAD metabolism
NF199_RS12220	COG1534	Rna-binding protein
NF199_RS12225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NF199_RS12230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NF199_RS12235	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NF199_RS12250	COG2755	lipolytic protein G-D-S-L family
NF199_RS12260	COG0398	Pfam SNARE associated Golgi protein
NF199_RS12285	COG1794	racemase activity, acting on amino acids and derivatives
NF199_RS12305	COG0656	L-ascorbic acid biosynthetic process
NF199_RS12335	COG3677	Transposase
NF199_RS12375	COG0642	Histidine kinase
NF199_RS12375	COG5002	protein histidine kinase activity
NF199_RS12380	COG0745	RESPONSE REGULATOR receiver
NF199_RS12385	COG2311	Membrane
NF199_RS12395	COG0454	-acetyltransferase
NF199_RS12400	COG0563	adenylate kinase activity
NF199_RS12410	COG2814	Major facilitator Superfamily
NF199_RS12415	COG0456	acetyltransferase
NF199_RS12420	COG2318	DinB family
NF199_RS12430	COG0561	phosphatase activity
NF199_RS12435	COG0561	phosphatase activity
NF199_RS12445	COG1482	cell wall glycoprotein biosynthetic process
NF199_RS12450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF199_RS12450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF199_RS12450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF199_RS12455	COG3711	transcriptional antiterminator
NF199_RS12455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF199_RS12465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NF199_RS12470	COG0583	DNA-binding transcription factor activity
NF199_RS12475	COG2814	Major facilitator Superfamily
NF199_RS12480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NF199_RS12480	COG2124	cytochrome p450
NF199_RS12485	COG1309	transcriptional regulator
NF199_RS12490	COG2226	methyltransferase
NF199_RS12505	COG2116	formate transmembrane transporter activity
NF199_RS12510	COG5609	conserved protein (DUF2294)
NF199_RS12515	COG3383	formate dehydrogenase (NAD+) activity
NF199_RS12520	COG2427	Protein of unknown function (DUF1641)
NF199_RS12530	COG0626	cystathionine gamma-synthase activity
NF199_RS12535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NF199_RS12560	COG0768	penicillin binding
NF199_RS12575	COG0826	peptidase U32
NF199_RS12580	COG0826	peptidase U32
NF199_RS12585	COG4122	O-methyltransferase activity
NF199_RS12590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NF199_RS12615	COG0628	permease
NF199_RS12620	COG1126	abc transporter atp-binding protein
NF199_RS12625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF199_RS12630	COG0765	amino acid transport
NF199_RS12635	COG0765	amino acid transport
NF199_RS12650	COG3881	PFAM PRC-barrel domain
NF199_RS12660	COG0457	Tetratricopeptide repeat
NF199_RS12670	COG1104	cysteine desulfurase activity
NF199_RS12675	COG1959	2 iron, 2 sulfur cluster binding
NF199_RS12680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NF199_RS12685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NF199_RS12710	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF199_RS12710	COG4991	sh3 domain protein
NF199_RS12710	COG3103	Sh3 type 3 domain protein
NF199_RS12720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NF199_RS12730	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NF199_RS12730	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NF199_RS12735	COG5416	Lipopolysaccharide assembly protein A domain
NF199_RS12740	COG0490	domain, Protein
NF199_RS12745	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NF199_RS12745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NF199_RS12755	COG2244	polysaccharide biosynthetic process
NF199_RS12760	COG2323	membrane
NF199_RS12770	COG1862	Preprotein translocase
NF199_RS12810	COG1388	LysM domain
NF199_RS12820	COG0157	Belongs to the NadC ModD family
NF199_RS12825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NF199_RS12830	COG1104	cysteine desulfurase activity
NF199_RS12835	COG1827	regulation of RNA biosynthetic process
NF199_RS12840	COG0077	Prephenate dehydratase
NF199_RS12860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NF199_RS12865	COG2868	ribosomal protein
NF199_RS12875	COG1994	Peptidase M50
NF199_RS12880	COG0739	heme binding
NF199_RS12885	COG2894	cell division
NF199_RS12890	COG0850	regulation of cytokinetic process
NF199_RS12895	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NF199_RS12905	COG1077	Cell shape determining protein MreB Mrl
NF199_RS12925	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NF199_RS12930	COG0285	dihydrofolate synthase activity
NF199_RS12935	COG0525	valine-tRNA ligase activity
NF199_RS12945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NF199_RS12950	COG1388	LysM domain
NF199_RS12960	COG0113	porphobilinogen synthase activity
NF199_RS12965	COG1587	Uroporphyrinogen-III synthase
NF199_RS12975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NF199_RS12995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NF199_RS13000	COG0470	DNA polymerase III
NF199_RS13000	COG1067	ATP-dependent peptidase activity
NF199_RS13015	COG0457	Tetratricopeptide repeat
NF199_RS13015	COG1477	protein flavinylation
NF199_RS13030	COG0473	3-isopropylmalate dehydrogenase activity
NF199_RS13045	COG0440	acetolactate synthase activity
NF199_RS13050	COG0028	Belongs to the TPP enzyme family
NF199_RS13075	COG0622	Phosphoesterase
NF199_RS13080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NF199_RS13090	COG5401	PFAM Sporulation and spore germination
NF199_RS13100	COG1846	Transcriptional regulator
NF199_RS13105	COG2197	response regulator
NF199_RS13110	COG0824	Thioesterase
NF199_RS13115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NF199_RS13120	COG1053	succinate dehydrogenase
NF199_RS13125	COG2009	succinate dehydrogenase
NF199_RS13130	COG1719	4-vinyl reductase, 4VR
NF199_RS13135	COG0527	aspartate kinase activity
NF199_RS13145	COG3118	belongs to the thioredoxin family
NF199_RS13150	COG3534	alpha-L-arabinofuranosidase
NF199_RS13155	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NF199_RS13160	COG2086	electron transfer activity
NF199_RS13170	COG1309	transcriptional regulator
NF199_RS13175	COG0318	PFAM AMP-dependent synthetase and ligase
NF199_RS13185	COG3766	membrane
NF199_RS13195	COG1796	DNA polymerase
NF199_RS13195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NF199_RS13200	COG1286	toxin biosynthetic process
NF199_RS13215	COG0072	phenylalanine-tRNA ligase activity
NF199_RS13215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF199_RS13220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NF199_RS13225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NF199_RS13235	COG3835	regulator
NF199_RS13240	COG0277	FAD linked oxidase domain protein
NF199_RS13245	COG0247	lactate metabolic process
NF199_RS13250	COG1966	Carbon starvation protein
NF199_RS13255	COG3534	alpha-L-arabinofuranosidase
NF199_RS13260	COG0395	ABC-type sugar transport system, permease component
NF199_RS13265	COG1175	transmembrane transport
NF199_RS13270	COG1653	transport
NF199_RS13280	COG0647	UMP catabolic process
NF199_RS13285	COG0235	Class ii aldolase
NF199_RS13290	COG1069	ribulokinase activity
NF199_RS13295	COG2160	L-arabinose isomerase activity
NF199_RS13300	COG3507	Belongs to the glycosyl hydrolase 43 family
NF199_RS13305	COG1363	Peptidase, m42
NF199_RS13315	COG3326	Membrane
NF199_RS13330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NF199_RS13335	COG1346	cytolysis
NF199_RS13340	COG1380	Effector of murein hydrolase LrgA
NF199_RS13345	COG3279	Response regulator of the LytR AlgR family
NF199_RS13350	COG3275	phosphorelay sensor kinase activity
NF199_RS13355	COG1011	Hydrolase
NF199_RS13370	COG0398	Pfam SNARE associated Golgi protein
NF199_RS13375	COG1484	DNA-dependent DNA replication
NF199_RS13380	COG3611	Membrane attachment protein
NF199_RS13395	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NF199_RS13400	COG1733	regulation of RNA biosynthetic process
NF199_RS13405	COG2814	Major facilitator Superfamily
NF199_RS13410	COG0656	L-ascorbic acid biosynthetic process
NF199_RS13415	COG0237	dephospho-CoA kinase activity
NF199_RS13420	COG1971	Probably functions as a manganese efflux pump
NF199_RS13425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NF199_RS13430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF199_RS13430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF199_RS13435	COG5002	protein histidine kinase activity
NF199_RS13440	COG0745	RESPONSE REGULATOR receiver
NF199_RS13450	COG0538	isocitrate dehydrogenase activity
NF199_RS13455	COG0372	Belongs to the citrate synthase family
NF199_RS13485	COG0628	permease
NF199_RS13490	COG3030	protein affecting phage T7 exclusion by the F plasmid
NF199_RS13495	COG0469	pyruvate kinase activity
NF199_RS13515	COG0281	malic enzyme
NF199_RS13520	COG0587	DNA-directed DNA polymerase activity
NF199_RS13540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NF199_RS13550	COG4109	DRTGG domain
NF199_RS13560	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS13580	COG0521	Mo-molybdopterin cofactor biosynthetic process
NF199_RS13590	COG0827	DNA restriction-modification system
NF199_RS13595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NF199_RS13600	COG3874	Sporulation protein YtfJ
NF199_RS13610	COG1714	RDD family
NF199_RS13615	COG0616	signal peptide processing
NF199_RS13620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NF199_RS13625	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NF199_RS13630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF199_RS13645	COG1104	cysteine desulfurase activity
NF199_RS13650	COG1114	Component of the transport system for branched-chain amino acids
NF199_RS13660	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NF199_RS13665	COG1309	transcriptional regulator
NF199_RS13670	COG1956	GAF domain-containing protein
NF199_RS13685	COG1012	belongs to the aldehyde dehydrogenase family
NF199_RS13690	COG4282	regulation of fungal-type cell wall biogenesis
NF199_RS13735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NF199_RS13735	COG1017	nitric oxide dioxygenase activity
NF199_RS13745	COG0693	protein deglycase activity
NF199_RS13765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NF199_RS13770	COG1378	Sugar-specific transcriptional regulator TrmB
NF199_RS13795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF199_RS13800	COG0454	-acetyltransferase
NF199_RS13805	COG0517	IMP dehydrogenase activity
NF199_RS13810	COG0123	including yeast histone deacetylase and acetoin utilization protein
NF199_RS13815	COG1360	Flagellar Motor Protein
NF199_RS13820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NF199_RS13825	COG1609	Transcriptional regulator
NF199_RS13830	COG1605	Chorismate mutase
NF199_RS13830	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NF199_RS13835	COG3118	belongs to the thioredoxin family
NF199_RS13840	COG4980	gas vesicle protein
NF199_RS13845	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NF199_RS13855	COG1674	ftsk spoiiie
NF199_RS13860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF199_RS13870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF199_RS13880	COG1363	Peptidase, m42
NF199_RS13885	COG5584	Small secreted protein
NF199_RS13890	COG0281	malic enzyme
NF199_RS13895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF199_RS13910	COG0510	thiamine kinase activity
NF199_RS13915	COG1597	lipid kinase activity
NF199_RS13925	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NF199_RS13930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NF199_RS13935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF199_RS13940	COG2252	PERMEase
NF199_RS13945	COG4473	ABC transporter
NF199_RS13950	COG1131	(ABC) transporter
NF199_RS13955	COG1349	DNA-binding transcription factor activity
NF199_RS13960	COG1187	pseudouridine synthase activity
NF199_RS13965	COG2244	polysaccharide biosynthetic process
NF199_RS13970	COG2081	HI0933 family
NF199_RS13975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NF199_RS13985	COG1609	Transcriptional regulator
NF199_RS13990	COG1653	transport
NF199_RS13995	COG1175	transmembrane transport
NF199_RS14000	COG0395	ABC-type sugar transport system, permease component
NF199_RS14005	COG1486	melibiose metabolic process
NF199_RS14015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF199_RS14030	COG1366	Belongs to the anti-sigma-factor antagonist family
NF199_RS14030	COG2202	Pas domain
NF199_RS14035	COG2814	Major facilitator Superfamily
NF199_RS14040	COG5522	Integral membrane protein (intg_mem_TP0381)
NF199_RS14045	COG0577	efflux transmembrane transporter activity
NF199_RS14050	COG1136	(ABC) transporter
NF199_RS14055	COG2205	protein histidine kinase activity
NF199_RS14060	COG0745	RESPONSE REGULATOR receiver
NF199_RS14065	COG0577	efflux transmembrane transporter activity
NF199_RS14070	COG1136	(ABC) transporter
NF199_RS14090	COG1131	(ABC) transporter
NF199_RS14095	COG1725	Transcriptional regulator
NF199_RS14110	COG1242	4 iron, 4 sulfur cluster binding
NF199_RS14115	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NF199_RS14125	COG0584	glycerophosphoryl diester phosphodiesterase
NF199_RS14135	COG2267	carboxylic ester hydrolase activity
NF199_RS14140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NF199_RS14145	COG1113	amino acid transport
NF199_RS14150	COG0367	asparagine synthase
NF199_RS14170	COG1506	peptidase
NF199_RS14175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NF199_RS14180	COG1116	anion transmembrane transporter activity
NF199_RS14185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF199_RS14190	COG0494	nUDIX hydrolase
NF199_RS14195	COG4824	toxin secretion phage lysis holin
NF199_RS14200	COG0783	Belongs to the Dps family
NF199_RS14225	COG0288	reversible hydration of carbon dioxide
NF199_RS14240	COG1294	oxidase, subunit
NF199_RS14250	COG4948	Mandelate Racemase Muconate Lactonizing
NF199_RS14260	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NF199_RS14265	COG0596	Alpha beta hydrolase
NF199_RS14280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NF199_RS14285	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NF199_RS14410	COG3859	Proton-coupled thiamine transporter YuaJ
NF199_RS14415	COG2268	Band 7 protein
NF199_RS14420	COG1585	Membrane protein implicated in regulation of membrane protease activity
NF199_RS14425	COG2318	DinB family
NF199_RS14435	COG1454	alcohol dehydrogenase
NF199_RS14440	COG1012	belongs to the aldehyde dehydrogenase family
NF199_RS14445	COG1510	regulation of RNA biosynthetic process
NF199_RS14455	COG0569	domain protein
NF199_RS14460	COG1705	Flagellar rod assembly protein muramidase FlgJ
NF199_RS14465	COG1017	nitric oxide dioxygenase activity
NF199_RS14465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NF199_RS14490	COG0628	permease
NF199_RS14495	COG0673	inositol 2-dehydrogenase activity
NF199_RS14500	COG0693	protein deglycase activity
NF199_RS14505	COG0840	transmembrane signaling receptor activity
NF199_RS14510	COG0840	transmembrane signaling receptor activity
NF199_RS14515	COG0840	transmembrane signaling receptor activity
NF199_RS14520	COG0840	transmembrane signaling receptor activity
NF199_RS14535	COG2070	2-Nitropropane dioxygenase
NF199_RS14540	COG0432	Pfam Uncharacterised protein family UPF0047
NF199_RS14545	COG0366	Alpha amylase catalytic
NF199_RS14550	COG1253	flavin adenine dinucleotide binding
NF199_RS14555	COG2738	Putative neutral zinc metallopeptidase
NF199_RS14570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NF199_RS14595	COG1335	isochorismatase
NF199_RS14600	COG1979	alcohol dehydrogenase
NF199_RS14610	COG2155	Conserved Protein
NF199_RS14615	COG1098	S1 RNA binding domain
NF199_RS14620	COG0436	Aminotransferase
NF199_RS14625	COG1522	sequence-specific DNA binding
NF199_RS14630	COG2267	carboxylic ester hydrolase activity
NF199_RS14640	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NF199_RS14645	COG2205	protein histidine kinase activity
NF199_RS14655	COG5018	Exonuclease
NF199_RS14660	COG2814	Major facilitator Superfamily
NF199_RS14665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF199_RS14670	COG3011	Protein conserved in bacteria
NF199_RS14680	COG3290	protein histidine kinase activity
NF199_RS14685	COG4565	transcriptional regulatory protein
NF199_RS14690	COG1744	ABC transporter substrate-binding protein PnrA-like
NF199_RS14695	COG3845	ABC transporter
NF199_RS14700	COG4603	Belongs to the binding-protein-dependent transport system permease family
NF199_RS14705	COG1079	Belongs to the binding-protein-dependent transport system permease family
NF199_RS14715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NF199_RS14715	COG2111	Na H antiporter
NF199_RS14720	COG2111	Na H antiporter
NF199_RS14725	COG1006	Multisubunit Na H antiporter MnhC subunit
NF199_RS14730	COG0651	ATP synthesis coupled electron transport
NF199_RS14735	COG1863	multisubunit Na H antiporter MnhE subunit
NF199_RS14740	COG2212	antiporter activity
NF199_RS14745	COG1320	monovalent cation:proton antiporter activity
NF199_RS14750	COG2050	protein possibly involved in aromatic compounds catabolism
NF199_RS14755	COG2197	response regulator
NF199_RS14760	COG4585	Histidine kinase
NF199_RS14785	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NF199_RS14790	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NF199_RS14795	COG1335	isochorismatase
NF199_RS14800	COG5506	Protein of unknown function (DUF1694)
NF199_RS14815	COG0628	permease
NF199_RS14825	COG1418	mRNA catabolic process
NF199_RS14830	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS14840	COG1511	domain protein
NF199_RS14845	COG1674	ftsk spoiiie
NF199_RS14845	COG0433	COG0433 Predicted ATPase
NF199_RS14850	COG4499	WXG100 protein secretion system (Wss), protein YukC
NF199_RS14855	COG5417	Belongs to the EsaB family
NF199_RS14860	COG4842	Belongs to the WXG100 family
NF199_RS14865	COG2508	Transcriptional regulator
NF199_RS14865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NF199_RS14870	COG0686	Belongs to the AlaDH PNT family
NF199_RS14875	COG5634	Uncharacterized conserved protein (DUF2278)
NF199_RS14880	COG3251	PFAM MbtH domain protein
NF199_RS14890	COG3433	isochorismatase activity
NF199_RS14890	COG1535	isochorismatase
NF199_RS14895	COG1021	2,3-dihydroxybenzoate-AMP ligase
NF199_RS14900	COG1169	isochorismate synthase
NF199_RS14905	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS14910	COG2819	hydrolase of the alpha beta superfamily
NF199_RS14915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NF199_RS14920	COG1268	BioY protein
NF199_RS14925	COG2056	Na+-H+ antiporter family
NF199_RS14935	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NF199_RS14940	COG3584	3D domain protein
NF199_RS14955	COG1252	NADH dehydrogenase
NF199_RS14985	COG1131	(ABC) transporter
NF199_RS15005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF199_RS15010	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NF199_RS15015	COG0316	Belongs to the HesB IscA family
NF199_RS15025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF199_RS15035	COG1252	NADH dehydrogenase
NF199_RS15040	COG4837	Protein of unknown function (DUF1462)
NF199_RS15045	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NF199_RS15050	COG0823	Involved in the tonB-independent uptake of proteins
NF199_RS15050	COG1506	peptidase
NF199_RS15050	COG4946	Tricorn protease homolog
NF199_RS15060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NF199_RS15065	COG0460	homoserine dehydrogenase
NF199_RS15070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NF199_RS15075	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NF199_RS15080	COG0647	UMP catabolic process
NF199_RS15085	COG2445	Protein of unknown function DUF86
NF199_RS15090	COG4470	Protein conserved in bacteria
NF199_RS15100	COG0739	heme binding
NF199_RS15110	COG0737	Belongs to the 5'-nucleotidase family
NF199_RS15115	COG0730	response to heat
NF199_RS15120	COG1801	Protein of unknown function DUF72
NF199_RS15135	COG2508	Transcriptional regulator
NF199_RS15160	COG2814	Major facilitator Superfamily
NF199_RS15165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NF199_RS15170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF199_RS15175	COG2356	endonuclease I
NF199_RS15180	COG3842	ATPase activity
NF199_RS15185	COG2188	Transcriptional regulator
NF199_RS15190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NF199_RS15195	COG0395	ABC-type sugar transport system, permease component
NF199_RS15200	COG1175	transmembrane transport
NF199_RS15205	COG1653	transport
NF199_RS15210	COG2222	sugar isomerase
NF199_RS15215	COG0789	Transcriptional regulator
NF199_RS15245	COG0322	excinuclease ABC activity
NF199_RS15250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF199_RS15270	COG3409	Peptidoglycan-binding domain 1 protein
NF199_RS15275	COG0719	Fe-S assembly protein
NF199_RS15280	COG0822	iron-sulfur transferase activity
NF199_RS15285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NF199_RS15290	COG0719	Fe-S assembly protein
NF199_RS15295	COG0396	ATPase activity
NF199_RS15305	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NF199_RS15310	COG1464	Belongs to the NlpA lipoprotein family
NF199_RS15315	COG2011	ABC-type metal ion transport system permease component
NF199_RS15320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NF199_RS15330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF199_RS15335	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NF199_RS15350	COG1393	Belongs to the ArsC family
NF199_RS15355	COG1960	acyl-CoA dehydrogenase activity
NF199_RS15360	COG0183	Belongs to the thiolase family
NF199_RS15365	COG1250	3-hydroxyacyl-CoA dehydrogenase
NF199_RS15365	COG1024	Enoyl-CoA hydratase
NF199_RS15385	COG5577	PFAM Coat F domain
NF199_RS15390	COG1846	Transcriptional regulator
NF199_RS15395	COG0477	Major facilitator Superfamily
NF199_RS15400	COG1942	4-Oxalocrotonate Tautomerase
NF199_RS15405	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS15410	COG0583	DNA-binding transcription factor activity
NF199_RS15420	COG0583	DNA-binding transcription factor activity
NF199_RS15440	COG1120	ATPase activity
NF199_RS15455	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS15460	COG0783	Belongs to the Dps family
NF199_RS15465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF199_RS15470	COG0745	RESPONSE REGULATOR receiver
NF199_RS15475	COG2205	protein histidine kinase activity
NF199_RS15475	COG2770	Histidine kinase
NF199_RS15485	COG1309	transcriptional regulator
NF199_RS15490	COG0114	fumarate hydratase activity
NF199_RS15500	COG0697	spore germination
NF199_RS15505	COG0814	amino acid
NF199_RS15515	COG2197	response regulator
NF199_RS15520	COG4585	Histidine kinase
NF199_RS15530	COG3595	metallopeptidase activity
NF199_RS15535	COG1842	Phage shock protein A
NF199_RS15540	COG4758	membrane
NF199_RS15550	COG2096	Adenosyltransferase
NF199_RS15555	COG1120	ATPase activity
NF199_RS15560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF199_RS15570	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS15575	COG3386	PFAM SMP-30 Gluconolaconase
NF199_RS15580	COG2205	protein histidine kinase activity
NF199_RS15585	COG0745	RESPONSE REGULATOR receiver
NF199_RS15595	COG1191	sigma factor activity
NF199_RS15605	COG2140	Oxalate decarboxylase
NF199_RS15615	COG1120	ATPase activity
NF199_RS15620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF199_RS15625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF199_RS15630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF199_RS15635	COG0531	amino acid
NF199_RS15645	COG1988	membrane-bound metal-dependent
NF199_RS15650	COG1368	sulfuric ester hydrolase activity
NF199_RS15655	COG1910	domain protein
NF199_RS15660	COG0725	ABC transporter, periplasmic molybdate-binding protein
NF199_RS15665	COG4149	molybdate abc transporter
NF199_RS15670	COG2197	response regulator
NF199_RS15675	COG3850	Histidine kinase
NF199_RS15680	COG1131	(ABC) transporter
NF199_RS15690	COG0842	Transport permease protein
NF199_RS15695	COG0656	L-ascorbic acid biosynthetic process
NF199_RS15715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NF199_RS15720	COG3973	AAA domain
NF199_RS15725	COG2860	membrane
NF199_RS15735	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NF199_RS15740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NF199_RS15745	COG2217	Heavy metal translocating P-type atpase
NF199_RS15750	COG2217	Heavy metal translocating P-type atpase
NF199_RS15755	COG2608	mercury ion transmembrane transporter activity
NF199_RS15760	COG1937	Protein conserved in bacteria
NF199_RS15765	COG0673	inositol 2-dehydrogenase activity
NF199_RS15775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF199_RS15780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NF199_RS15785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF199_RS15790	COG1126	abc transporter atp-binding protein
NF199_RS15795	COG0765	amino acid transport
NF199_RS15800	COG0765	amino acid transport
NF199_RS15805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF199_RS15810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF199_RS15820	COG0583	DNA-binding transcription factor activity
NF199_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS15870	COG0557	exoribonuclease II activity
NF199_RS15875	COG1647	Serine aminopeptidase, S33
NF199_RS15880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NF199_RS15885	COG1476	TRANSCRIPTIONal
NF199_RS15890	COG1396	sequence-specific DNA binding
NF199_RS15895	COG1396	sequence-specific DNA binding
NF199_RS15900	COG1733	regulation of RNA biosynthetic process
NF199_RS15925	COG1131	(ABC) transporter
NF199_RS15930	COG1174	glycine betaine transport
NF199_RS15935	COG1732	Glycine betaine
NF199_RS15940	COG1174	glycine betaine transport
NF199_RS15945	COG0517	IMP dehydrogenase activity
NF199_RS15945	COG1125	glycine betaine transport
NF199_RS15950	COG1510	regulation of RNA biosynthetic process
NF199_RS15955	COG1174	glycine betaine transport
NF199_RS15960	COG1732	Glycine betaine
NF199_RS15965	COG1174	glycine betaine transport
NF199_RS15970	COG0517	IMP dehydrogenase activity
NF199_RS15970	COG1125	glycine betaine transport
NF199_RS15975	COG1510	regulation of RNA biosynthetic process
NF199_RS15980	COG2095	MarC family integral membrane protein
NF199_RS15985	COG3064	Membrane
NF199_RS15990	COG4640	response to antibiotic
NF199_RS15995	COG0456	acetyltransferase
NF199_RS16010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NF199_RS16030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF199_RS16035	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NF199_RS16045	COG2234	aminopeptidase activity
NF199_RS16065	COG0126	phosphoglycerate kinase activity
NF199_RS16070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NF199_RS16075	COG2390	Transcriptional regulator
NF199_RS16080	COG2814	Major facilitator Superfamily
NF199_RS16085	COG1609	Transcriptional regulator
NF199_RS16090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF199_RS16100	COG0583	DNA-binding transcription factor activity
NF199_RS16105	COG0697	spore germination
NF199_RS16110	COG1113	amino acid transport
NF199_RS16115	COG1609	Transcriptional regulator
NF199_RS16125	COG0561	phosphatase activity
NF199_RS16130	COG1737	Transcriptional regulator
NF199_RS16135	COG1070	Carbohydrate kinase
NF199_RS16175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF199_RS16180	COG2186	Transcriptional regulator
NF199_RS16185	COG1620	l-lactate permease
NF199_RS16190	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NF199_RS16200	COG5039	Polysaccharide pyruvyl transferase
NF199_RS16205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NF199_RS16210	COG0110	maltose O-acetyltransferase activity
NF199_RS16215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NF199_RS16220	COG2244	polysaccharide biosynthetic process
NF199_RS16225	COG1216	Glycosyl transferase, family 2
NF199_RS16230	COG5039	Polysaccharide pyruvyl transferase
NF199_RS16235	COG1216	Glycosyl transferase, family 2
NF199_RS16245	COG0438	transferase activity, transferring glycosyl groups
NF199_RS16250	COG1215	transferase activity, transferring glycosyl groups
NF199_RS16255	COG0438	transferase activity, transferring glycosyl groups
NF199_RS16260	COG1086	Polysaccharide biosynthesis protein
NF199_RS16265	COG0489	protein tyrosine kinase activity
NF199_RS16270	COG3944	biosynthesis protein
NF199_RS16275	COG1396	sequence-specific DNA binding
NF199_RS16280	COG2272	Belongs to the type-B carboxylesterase lipase family
NF199_RS16285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NF199_RS16290	COG2364	Membrane
NF199_RS16295	COG0456	acetyltransferase
NF199_RS16300	COG3479	Phenolic acid decarboxylase
NF199_RS16355	COG2223	nitrite transmembrane transporter activity
NF199_RS16360	COG1609	Transcriptional regulator
NF199_RS16370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NF199_RS16375	COG0366	Alpha amylase catalytic
NF199_RS16380	COG1554	hydrolase, family 65, central catalytic
NF199_RS16385	COG5521	maltodextrose utilization protein MalA
NF199_RS16390	COG3833	ABC-type maltose transport systems, permease component
NF199_RS16395	COG1175	transmembrane transport
NF199_RS16400	COG2182	Extracellular solute-binding protein
NF199_RS16405	COG0366	Alpha amylase catalytic
NF199_RS16410	COG1609	Transcriptional regulator
NF199_RS16415	COG1611	Belongs to the LOG family
NF199_RS16420	COG1694	Mazg nucleotide pyrophosphohydrolase
NF199_RS16425	COG0659	secondary active sulfate transmembrane transporter activity
NF199_RS16430	COG0288	reversible hydration of carbon dioxide
NF199_RS16435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NF199_RS16440	COG4290	ribonuclease
NF199_RS16445	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NF199_RS16450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF199_RS16460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NF199_RS16470	COG1051	belongs to the nudix hydrolase family
NF199_RS16475	COG0492	ferredoxin-NADP+ reductase activity
NF199_RS16480	COG0791	NLP P60 protein
NF199_RS16480	COG3883	PFAM NLP P60 protein
NF199_RS16490	COG5002	protein histidine kinase activity
NF199_RS16495	COG0745	RESPONSE REGULATOR receiver
NF199_RS16500	COG1132	(ABC) transporter
NF199_RS16505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NF199_RS16505	COG0140	phosphoribosyl-ATP diphosphatase activity
NF199_RS16530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NF199_RS16545	COG4990	cell redox homeostasis
NF199_RS16550	COG0110	maltose O-acetyltransferase activity
NF199_RS16570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NF199_RS16580	COG2188	Transcriptional regulator
NF199_RS16585	COG1309	transcriptional regulator
NF199_RS16590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NF199_RS16595	COG1950	PFAM Membrane protein of
NF199_RS16600	COG1983	PspC domain protein
NF199_RS16605	COG3595	metallopeptidase activity
NF199_RS16620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NF199_RS16630	COG4897	Protein conserved in bacteria
NF199_RS16635	COG3848	Pyruvate phosphate dikinase
NF199_RS16635	COG0574	Belongs to the PEP-utilizing enzyme family
NF199_RS16645	COG2814	Major facilitator Superfamily
NF199_RS16660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF199_RS16670	COG3409	Peptidoglycan-binding domain 1 protein
NF199_RS16670	COG0793	Belongs to the peptidase S41A family
NF199_RS16675	COG3420	alginic acid biosynthetic process
NF199_RS16680	COG2177	Part of the ABC transporter FtsEX involved in
NF199_RS16685	COG2884	Cell division ATP-binding protein ftsE
NF199_RS16690	COG2010	Cytochrome c
NF199_RS16710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NF199_RS16725	COG1516	flagellar protein fliS
NF199_RS16730	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NF199_RS16735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NF199_RS16755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NF199_RS16760	COG4786	Flagellar basal body rod
NF199_RS16760	COG1256	bacterial-type flagellum assembly
NF199_RS16765	COG3418	PFAM FlgN family protein
NF199_RS16770	COG2747	anti-sigma28 factor FlgM
NF199_RS16780	COG1040	competence protein
NF199_RS16790	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NF199_RS16795	COG1307	EDD domain protein, DegV family
NF199_RS16800	COG2197	response regulator
NF199_RS16805	COG4585	Histidine kinase
NF199_RS16810	COG1739	Uncharacterized protein family UPF0029
NF199_RS16815	COG1316	TRANSCRIPTIONal
NF199_RS16820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NF199_RS16825	COG0438	transferase activity, transferring glycosyl groups
NF199_RS16830	COG1215	transferase activity, transferring glycosyl groups
NF199_RS16835	COG3206	protein involved in exopolysaccharide biosynthesis
NF199_RS16840	COG3307	-O-antigen
NF199_RS16845	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NF199_RS16850	COG0297	glycogen (starch) synthase activity
NF199_RS16850	COG0438	transferase activity, transferring glycosyl groups
NF199_RS16855	COG2244	polysaccharide biosynthetic process
NF199_RS16865	COG2247	cell wall binding repeat
NF199_RS16865	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF199_RS16870	COG2247	cell wall binding repeat
NF199_RS16870	COG2385	sporulation resulting in formation of a cellular spore
NF199_RS16880	COG1316	TRANSCRIPTIONal
NF199_RS16885	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NF199_RS16890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NF199_RS16895	COG1134	teichoic acid transport
NF199_RS16900	COG1682	transport, permease protein
NF199_RS16905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NF199_RS16915	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NF199_RS16920	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NF199_RS16925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NF199_RS16930	COG4193	domain, Protein
NF199_RS16935	COG1482	cell wall glycoprotein biosynthetic process
NF199_RS16940	COG0697	spore germination
NF199_RS16945	COG0814	amino acid
NF199_RS16955	COG1215	transferase activity, transferring glycosyl groups
NF199_RS16960	COG2814	Major facilitator Superfamily
NF199_RS16965	COG1316	TRANSCRIPTIONal
NF199_RS16970	COG0561	phosphatase activity
NF199_RS16975	COG2433	Pfam Transposase IS66
NF199_RS16980	COG0791	NLP P60 protein
NF199_RS16990	COG2843	Capsule synthesis protein
NF199_RS17000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NF199_RS17005	COG0697	spore germination
NF199_RS17020	COG1609	Transcriptional regulator
NF199_RS17025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NF199_RS17035	COG1129	ABC transporter
NF199_RS17040	COG1172	Belongs to the binding-protein-dependent transport system permease family
NF199_RS17045	COG1879	ABC-type sugar transport system periplasmic component
NF199_RS17050	COG3103	Sh3 type 3 domain protein
NF199_RS17055	COG2249	NAD(P)H dehydrogenase (quinone) activity
NF199_RS17060	COG3527	Alpha-acetolactate decarboxylase
NF199_RS17065	COG0028	Belongs to the TPP enzyme family
NF199_RS17070	COG0583	DNA-binding transcription factor activity
NF199_RS17075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NF199_RS17090	COG5337	Spore coat protein CotH
NF199_RS17100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NF199_RS17110	COG0405	Gamma-glutamyltransferase
NF199_RS17115	COG1522	sequence-specific DNA binding
NF199_RS17120	COG2059	Chromate
NF199_RS17125	COG2059	Chromate
NF199_RS17135	COG0655	NAD(P)H dehydrogenase (quinone) activity
NF199_RS17140	COG0583	DNA-binding transcription factor activity
NF199_RS17170	COG5444	nuclease activity
NF199_RS17185	COG3878	Protein conserved in bacteria
NF199_RS17195	COG4464	protein tyrosine phosphatase activity
NF199_RS17200	COG0489	protein tyrosine kinase activity
NF199_RS17205	COG3944	biosynthesis protein
NF199_RS17215	COG4715	Zinc finger, swim domain protein
NF199_RS17220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NF199_RS17225	COG0561	phosphatase activity
NF199_RS17230	COG1349	DNA-binding transcription factor activity
NF199_RS17235	COG0629	single-stranded DNA binding
NF199_RS17260	COG0457	Tetratricopeptide repeat
NF199_RS17265	COG4786	Flagellar basal body rod
NF199_RS17270	COG4786	Flagellar basal body rod
NF199_RS17275	COG1077	Cell shape determining protein MreB Mrl
NF199_RS17280	COG1609	Transcriptional regulator
NF199_RS17285	COG1846	Transcriptional regulator
NF199_RS17290	COG2814	Major facilitator Superfamily
NF199_RS17295	COG1953	Uracil, thiamine, allantoin
NF199_RS17300	COG0477	Major facilitator Superfamily
NF199_RS17305	COG1335	isochorismatase
NF199_RS17310	COG0004	ammonium transporteR
NF199_RS17315	COG0347	Belongs to the P(II) protein family
NF199_RS17320	COG0772	Belongs to the SEDS family
NF199_RS17325	COG0671	phosphoesterase, PA-phosphatase related
NF199_RS17335	COG0739	heme binding
NF199_RS17340	COG1247	-acetyltransferase
NF199_RS17355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NF199_RS17370	COG0726	polysaccharide deacetylase
NF199_RS17380	COG1959	2 iron, 2 sulfur cluster binding
NF199_RS17395	COG0831	urea catabolic process
NF199_RS17400	COG3237	CsbD-like
NF199_RS17405	COG1994	Peptidase M50
NF199_RS17410	COG0457	Tetratricopeptide repeat
NF199_RS17420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NF199_RS17430	COG2304	oxidoreductase activity
NF199_RS17435	COG2304	oxidoreductase activity
NF199_RS17440	COG2385	sporulation resulting in formation of a cellular spore
NF199_RS17445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NF199_RS17455	COG4836	Membrane
NF199_RS17525	COG0698	ribose 5-phosphate isomerase
NF199_RS17530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NF199_RS17540	COG0009	L-threonylcarbamoyladenylate synthase
NF199_RS17545	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NF199_RS17565	COG2890	protein-(glutamine-N5) methyltransferase activity
NF199_RS17570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NF199_RS17575	COG0346	lactoylglutathione lyase activity
NF199_RS17580	COG0789	Transcriptional regulator
NF199_RS17585	COG0679	Auxin Efflux Carrier
NF199_RS17590	COG0281	malic enzyme
NF199_RS17605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NF199_RS17615	COG1494	fructose-1,6-bisphosphatase
NF199_RS17620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NF199_RS17630	COG0191	fructose-bisphosphate aldolase activity
NF199_RS17635	COG2204	response regulator
NF199_RS17640	COG4821	SIS domain
NF199_RS17655	COG0247	lactate metabolic process
NF199_RS17655	COG2181	nitrate reductase activity
NF199_RS17660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NF199_RS17675	COG1132	(ABC) transporter
NF199_RS17690	COG2181	nitrate reductase activity
NF199_RS17695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NF199_RS17700	COG1140	nitrate reductase beta subunit
NF199_RS17705	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NF199_RS17710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NF199_RS17720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NF199_RS17725	COG2223	nitrite transmembrane transporter activity
NF199_RS17735	COG4506	Protein conserved in bacteria
NF199_RS17745	COG3391	amine dehydrogenase activity
NF199_RS17750	COG3391	amine dehydrogenase activity
NF199_RS17755	COG0457	Tetratricopeptide repeat
NF199_RS17770	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NF199_RS17775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF199_RS17790	COG1994	Peptidase M50
NF199_RS17795	COG1942	4-Oxalocrotonate Tautomerase
NF199_RS17800	COG1846	Transcriptional regulator
NF199_RS17805	COG0531	amino acid
NF199_RS17810	COG3465	dGTPase activity
NF199_RS17815	COG1078	dGTPase activity
NF199_RS17830	COG1695	Transcriptional regulator
NF199_RS17840	COG1131	(ABC) transporter
NF199_RS17845	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NF199_RS17875	COG0583	DNA-binding transcription factor activity
NF199_RS17880	COG2855	membrane
NF199_RS17885	COG0280	phosphate acetyltransferase
NF199_RS17895	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS17900	COG0436	Aminotransferase
NF199_RS17930	COG2814	Major facilitator Superfamily
NF199_RS17935	COG2814	Major facilitator Superfamily
NF199_RS17940	COG0833	amino acid
NF199_RS17945	COG4187	Peptidase family M20/M25/M40
NF199_RS17950	COG1012	belongs to the aldehyde dehydrogenase family
NF199_RS17955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NF199_RS17960	COG2205	protein histidine kinase activity
NF199_RS17965	COG0745	RESPONSE REGULATOR receiver
NF199_RS17980	COG1131	(ABC) transporter
NF199_RS17985	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NF199_RS17990	COG1091	dTDP-4-dehydrorhamnose reductase activity
NF199_RS17995	COG1088	dTDP-glucose 4,6-dehydratase activity
NF199_RS18000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NF199_RS18005	COG3980	spore coat polysaccharide biosynthesis protein
NF199_RS18015	COG2089	acid synthase
NF199_RS18020	COG0456	acetyltransferase
NF199_RS18025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NF199_RS18030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NF199_RS18035	COG0463	Glycosyl transferase, family 2
NF199_RS18045	COG2363	Small membrane protein
NF199_RS18050	COG2233	PERMEase
NF199_RS18065	COG1216	Glycosyl transferase, family 2
NF199_RS18080	COG1695	Transcriptional regulator
NF199_RS18085	COG0351	phosphomethylpyrimidine kinase
NF199_RS18095	COG1621	beta-fructofuranosidase activity
NF199_RS18100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF199_RS18100	COG1263	PTS System
NF199_RS18105	COG3711	transcriptional antiterminator
NF199_RS18115	COG1404	Belongs to the peptidase S8 family
NF199_RS18120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF199_RS18125	COG0778	Nitroreductase
NF199_RS18130	COG0772	Belongs to the SEDS family
NF199_RS18135	COG0454	-acetyltransferase
NF199_RS18155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NF199_RS18160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NF199_RS18165	COG2261	transglycosylase associated protein
NF199_RS18170	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NF199_RS18175	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NF199_RS18180	COG2246	polysaccharide biosynthetic process
NF199_RS18185	COG1309	transcriptional regulator
NF199_RS18205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NF199_RS18210	COG2837	iron assimilation
NF199_RS18230	COG0583	DNA-binding transcription factor activity
NF199_RS18240	COG1346	cytolysis
NF199_RS18245	COG4895	conserved protein (DUF2196)
NF199_RS18250	COG0789	Transcriptional regulator
NF199_RS18255	COG5504	Zn-dependent protease
NF199_RS18260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NF199_RS18265	COG0346	lactoylglutathione lyase activity
NF199_RS18270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF199_RS18280	COG1442	glycosyl transferase family 8
NF199_RS18285	COG2357	RelA SpoT domain protein
NF199_RS18290	COG1575	Belongs to the MenA family. Type 1 subfamily
NF199_RS18305	COG1696	Membrane protein involved in D-alanine export
NF199_RS18315	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NF199_RS18320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF199_RS18325	COG1486	melibiose metabolic process
NF199_RS18330	COG1447	Phosphotransferase system cellobiose-specific component IIA
NF199_RS18335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF199_RS18340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF199_RS18345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF199_RS18345	COG3711	transcriptional antiterminator
NF199_RS18360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF199_RS18365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF199_RS18375	COG0640	Transcriptional regulator
NF199_RS18380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NF199_RS18385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF199_RS18390	COG1447	Phosphotransferase system cellobiose-specific component IIA
NF199_RS18395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF199_RS18400	COG2723	6-phospho-beta-galactosidase activity
NF199_RS18410	COG1482	cell wall glycoprotein biosynthetic process
NF199_RS18420	COG0753	catalase activity
NF199_RS18425	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NF199_RS18430	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NF199_RS18450	COG3279	Response regulator of the LytR AlgR family
NF199_RS18470	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NF199_RS18475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NF199_RS18480	COG4988	ABC transporter
NF199_RS18485	COG1294	oxidase, subunit
NF199_RS18490	COG1271	oxidase subunit
NF199_RS18495	COG3493	citrate carrier protein
NF199_RS18505	COG3842	ATPase activity
NF199_RS18510	COG2508	Transcriptional regulator
NF199_RS18515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF199_RS18525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NF199_RS18540	COG4894	glucomannan catabolic process
NF199_RS18545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NF199_RS18550	COG0500	methyltransferase
NF199_RS18555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF199_RS18570	COG0753	catalase activity
NF199_RS18570	COG0693	protein deglycase activity
NF199_RS18575	COG2851	Citrate transporter
NF199_RS18580	COG2273	Hydrolase Family 16
NF199_RS18590	COG2270	Major facilitator Superfamily
NF199_RS18595	COG0513	Belongs to the DEAD box helicase family
NF199_RS18605	COG0697	spore germination
NF199_RS18610	COG0589	response to stress
NF199_RS18675	COG3507	Belongs to the glycosyl hydrolase 43 family
NF199_RS18700	COG0010	Belongs to the arginase family
NF199_RS18705	COG0833	amino acid
NF199_RS18710	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NF199_RS18715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF199_RS18725	COG2390	Transcriptional regulator
NF199_RS18730	COG0561	phosphatase activity
NF199_RS18760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF199_RS18765	COG5294	Protein conserved in bacteria
NF199_RS18770	COG0577	efflux transmembrane transporter activity
NF199_RS18775	COG1136	(ABC) transporter
NF199_RS18780	COG2205	protein histidine kinase activity
NF199_RS18785	COG0745	RESPONSE REGULATOR receiver
NF199_RS18790	COG2205	protein histidine kinase activity
NF199_RS18795	COG0745	RESPONSE REGULATOR receiver
NF199_RS18825	COG1082	Xylose isomerase domain protein TIM barrel
NF199_RS18835	COG2814	Major facilitator Superfamily
NF199_RS18865	COG1349	DNA-binding transcription factor activity
NF199_RS18870	COG0667	Aldo Keto reductase
NF199_RS18875	COG2814	Major facilitator Superfamily
NF199_RS18890	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS18895	COG2197	response regulator
NF199_RS18900	COG4585	Histidine kinase
NF199_RS18905	COG3239	Fatty acid desaturase
NF199_RS18910	COG1309	transcriptional regulator
NF199_RS18915	COG1012	belongs to the aldehyde dehydrogenase family
NF199_RS18920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NF199_RS18930	COG0640	Transcriptional regulator
NF199_RS18935	COG2814	Major facilitator Superfamily
NF199_RS18940	COG1714	RDD family
NF199_RS18950	COG0450	alkyl hydroperoxide reductase
NF199_RS18955	COG3634	alkyl hydroperoxide reductase activity
NF199_RS18960	COG3177	Filamentation induced by cAMP protein fic
NF199_RS18965	COG1113	amino acid transport
NF199_RS18975	COG2080	2 iron, 2 sulfur cluster binding
NF199_RS18990	COG2068	MobA-Related Protein
NF199_RS18995	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NF199_RS19050	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NF199_RS19055	COG0667	Aldo Keto reductase
NF199_RS19060	COG0456	acetyltransferase
NF199_RS19070	COG0457	Tetratricopeptide repeat
NF199_RS19075	COG0010	Belongs to the arginase family
NF199_RS19080	COG0833	amino acid
NF199_RS19085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NF199_RS19090	COG5658	integral membrane protein
NF199_RS19095	COG0640	Transcriptional regulator
NF199_RS19100	COG3829	transcription factor binding
NF199_RS19110	COG0488	(ABC) transporter
NF199_RS19125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NF199_RS19130	COG3850	Histidine kinase
NF199_RS19130	COG5002	protein histidine kinase activity
NF199_RS19140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF199_RS19145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NF199_RS19150	COG4853	Protein conserved in bacteria
NF199_RS19155	COG4863	YycH protein
NF199_RS19160	COG5002	protein histidine kinase activity
NF199_RS19165	COG0745	RESPONSE REGULATOR receiver
NF199_RS19195	COG0346	lactoylglutathione lyase activity
NF199_RS19200	COG0305	Participates in initiation and elongation during chromosome replication
NF199_RS19215	COG3093	addiction module antidote protein HigA
NF199_RS19220	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NF199_RS19225	COG0297	glycogen (starch) synthase activity
NF199_RS19235	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NF199_RS19240	COG0438	transferase activity, transferring glycosyl groups
NF199_RS19260	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NF199_RS19265	COG4241	membrane
NF199_RS19275	COG5577	PFAM Coat F domain
NF199_RS19280	COG1733	regulation of RNA biosynthetic process
NF199_RS19290	COG0697	spore germination
NF199_RS19295	COG1621	beta-fructofuranosidase activity
NF199_RS19300	COG1621	beta-fructofuranosidase activity
NF199_RS19310	COG2318	DinB family
NF199_RS19315	COG2211	Major facilitator Superfamily
NF199_RS19325	COG0778	Nitroreductase
NF199_RS19335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF199_RS19340	COG1846	Transcriptional regulator
NF199_RS19345	COG2153	protein acetylation
NF199_RS19355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NF199_RS19360	COG0583	DNA-binding transcription factor activity
NF199_RS19365	COG1028	Short-chain dehydrogenase reductase Sdr
NF199_RS19370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF199_RS19375	COG0697	spore germination
NF199_RS19405	COG1331	Highly conserved protein containing a thioredoxin domain
NF199_RS19410	COG1266	CAAX protease self-immunity
NF199_RS19415	COG0477	Major facilitator Superfamily
NF199_RS19415	COG2814	Major facilitator Superfamily
NF199_RS19420	COG0346	lactoylglutathione lyase activity
NF199_RS19425	COG1609	Transcriptional regulator
NF199_RS19430	COG0708	Exodeoxyribonuclease III
NF199_RS19435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NF199_RS19440	COG2169	Transcriptional regulator
NF199_RS19450	COG0629	single-stranded DNA binding
NF199_RS19460	COG0012	GTP binding
NF199_RS19465	COG0243	molybdopterin cofactor binding
NF199_RS19470	COG4481	Protein conserved in bacteria
NF199_RS19475	COG3949	Membrane
NF199_RS19490	COG1475	DNA binding
NF199_RS19495	COG1192	Involved in chromosome partitioning
NF199_RS19520	COG1847	R3H domain protein
NF199_RS19525	COG0706	membrane insertase activity