locus-tag	class	description
IEN91_RS00010	COG0592	DNA-directed DNA polymerase activity
IEN91_RS00015	COG2501	S4 domain
IEN91_RS00030	COG0187	DNA topoisomerase II activity
IEN91_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEN91_RS00070	COG0516	GMP reductase activity
IEN91_RS00070	COG0517	IMP dehydrogenase activity
IEN91_RS00075	COG1686	Belongs to the peptidase S11 family
IEN91_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
IEN91_RS00105	COG1428	Deoxynucleoside kinase
IEN91_RS00110	COG1428	Deoxynucleoside kinase
IEN91_RS00115	COG3858	chitin binding
IEN91_RS00115	COG1388	LysM domain
IEN91_RS00120	COG1335	isochorismatase
IEN91_RS00125	COG0590	tRNA wobble adenosine to inosine editing
IEN91_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEN91_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IEN91_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IEN91_RS00195	COG3853	Toxic anion resistance protein (TelA)
IEN91_RS00200	COG1982	Orn Lys Arg decarboxylase major
IEN91_RS00210	COG3870	Protein conserved in bacteria
IEN91_RS00215	COG1728	Protein conserved in bacteria
IEN91_RS00220	COG0470	DNA polymerase III
IEN91_RS00225	COG1774	PSP1 C-terminal conserved region
IEN91_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IEN91_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IEN91_RS00250	COG2002	toxin-antitoxin pair type II binding
IEN91_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEN91_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEN91_RS00260	COG0084	hydrolase, TatD family'
IEN91_RS00265	COG3583	domain protein
IEN91_RS00265	COG3584	3D domain protein
IEN91_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IEN91_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IEN91_RS00285	COG4466	Protein conserved in bacteria
IEN91_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IEN91_RS00305	COG0251	oxidation-reduction process
IEN91_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEN91_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IEN91_RS00345	COG2002	toxin-antitoxin pair type II binding
IEN91_RS00350	COG2244	polysaccharide biosynthetic process
IEN91_RS00355	COG3956	TIGRFAM MazG family protein
IEN91_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IEN91_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IEN91_RS00380	COG1098	S1 RNA binding domain
IEN91_RS00395	COG2208	phosphoserine phosphatase activity
IEN91_RS00400	COG2304	oxidoreductase activity
IEN91_RS00405	COG0515	serine threonine protein kinase
IEN91_RS00410	COG0037	tRNA processing
IEN91_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IEN91_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEN91_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IEN91_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IEN91_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IEN91_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
IEN91_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IEN91_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IEN91_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IEN91_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IEN91_RS00475	COG1396	sequence-specific DNA binding
IEN91_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEN91_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IEN91_RS00565	COG4463	regulation of RNA biosynthetic process
IEN91_RS00570	COG3880	PFAM UvrB UvrC protein
IEN91_RS00580	COG0542	response to heat
IEN91_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IEN91_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IEN91_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
IEN91_RS00615	COG1045	serine acetyltransferase
IEN91_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IEN91_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEN91_RS00635	COG3688	RNA-binding protein containing a PIN domain
IEN91_RS00640	COG1595	DNA-templated transcription, initiation
IEN91_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IEN91_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
IEN91_RS00680	COG2813	Specifically methylates the guanine in position
IEN91_RS00695	COG1358	cellular component organization or biogenesis
IEN91_RS00720	COG0596	Alpha beta hydrolase
IEN91_RS00830	COG0201	protein transport
IEN91_RS00840	COG0024	Methionine aminopeptidase
IEN91_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IEN91_RS00875	COG1122	ATPase activity
IEN91_RS00880	COG1122	ATPase activity
IEN91_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEN91_RS00905	COG2226	methyltransferase
IEN91_RS00910	COG2318	DinB family
IEN91_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS00925	COG0489	protein tyrosine kinase activity
IEN91_RS00935	COG2194	sulfuric ester hydrolase activity
IEN91_RS00940	COG0726	polysaccharide deacetylase
IEN91_RS01000	COG0738	Major facilitator superfamily
IEN91_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEN91_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
IEN91_RS01025	COG0385	Bile acid
IEN91_RS01030	COG2819	hydrolase of the alpha beta superfamily
IEN91_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEN91_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEN91_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IEN91_RS01050	COG2207	Transcriptional regulator
IEN91_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IEN91_RS01055	COG3876	Protein conserved in bacteria
IEN91_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
IEN91_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IEN91_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IEN91_RS01070	COG1263	PTS System
IEN91_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IEN91_RS01085	COG1683	Conserved Protein
IEN91_RS01115	COG1595	DNA-templated transcription, initiation
IEN91_RS01120	COG5662	AntiSigma factor
IEN91_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IEN91_RS01130	COG4856	YbbR-like protein
IEN91_RS01160	COG1346	cytolysis
IEN91_RS01165	COG1380	Effector of murein hydrolase LrgA
IEN91_RS01170	COG1846	Transcriptional regulator
IEN91_RS01175	COG1113	amino acid transport
IEN91_RS01180	COG1011	Hydrolase
IEN91_RS01185	COG4585	Histidine kinase
IEN91_RS01190	COG2197	response regulator
IEN91_RS01195	COG1131	(ABC) transporter
IEN91_RS01215	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IEN91_RS01235	COG4221	oxidoreductase activity
IEN91_RS01235	COG3321	synthase
IEN91_RS01235	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS01235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS01240	COG3321	synthase
IEN91_RS01240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS01240	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS01240	COG0300	oxidoreductase activity
IEN91_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS01280	COG0531	amino acid
IEN91_RS01285	COG0584	glycerophosphoryl diester phosphodiesterase
IEN91_RS01290	COG2271	Major facilitator Superfamily
IEN91_RS01300	COG2368	4-hydroxyphenylacetate
IEN91_RS01310	COG3409	Peptidoglycan-binding domain 1 protein
IEN91_RS01325	COG0371	Dehydrogenase
IEN91_RS01335	COG1183	phosphatidylcholine synthase activity
IEN91_RS01340	COG0586	Pfam SNARE associated Golgi protein
IEN91_RS01345	COG0688	phosphatidylethanolamine metabolic process
IEN91_RS01360	COG1301	dicarboxylic acid transport
IEN91_RS01365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IEN91_RS01370	COG0833	amino acid
IEN91_RS01375	COG2040	homocysteine
IEN91_RS01380	COG1115	amino acid carrier protein
IEN91_RS01385	COG2066	Belongs to the glutaminase family
IEN91_RS01390	COG4191	Histidine kinase
IEN91_RS01395	COG0784	Response regulator, receiver
IEN91_RS01400	COG3173	Aminoglycoside phosphotransferase
IEN91_RS01410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEN91_RS01415	COG0778	Nitroreductase
IEN91_RS01420	COG0346	lactoylglutathione lyase activity
IEN91_RS01425	COG2259	Doxx family
IEN91_RS01430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IEN91_RS01440	COG3773	Cell wall hydrolase
IEN91_RS01445	COG3540	Alkaline phosphatase
IEN91_RS01450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IEN91_RS01455	COG0805	protein transport
IEN91_RS01465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEN91_RS01470	COG0477	Major facilitator Superfamily
IEN91_RS01475	COG1309	transcriptional regulator
IEN91_RS01480	COG0252	asparaginase activity
IEN91_RS01485	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IEN91_RS01490	COG3012	SEC-C Motif Domain Protein
IEN91_RS01490	COG1405	negative regulation of cell septum assembly
IEN91_RS01495	COG0667	Aldo Keto reductase
IEN91_RS01505	COG1595	DNA-templated transcription, initiation
IEN91_RS01510	COG1595	DNA-templated transcription, initiation
IEN91_RS01515	COG1876	peptidase activity
IEN91_RS01520	COG0457	Tetratricopeptide repeat
IEN91_RS01525	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS01530	COG0366	Alpha amylase catalytic
IEN91_RS01535	COG0803	Belongs to the bacterial solute-binding protein 9 family
IEN91_RS01540	COG1121	(ABC) transporter
IEN91_RS01545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IEN91_RS01550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEN91_RS01555	COG2310	stress, protein
IEN91_RS01560	COG2310	stress, protein
IEN91_RS01565	COG2310	stress, protein
IEN91_RS01570	COG0861	Integral membrane protein TerC family
IEN91_RS01580	COG3853	Toxic anion resistance protein (TelA)
IEN91_RS01585	COG0477	Major facilitator Superfamily
IEN91_RS01590	COG0517	IMP dehydrogenase activity
IEN91_RS01590	COG4175	Glycine betaine
IEN91_RS01595	COG4176	ABC-type proline glycine betaine transport system permease component
IEN91_RS01600	COG2113	Glycine betaine
IEN91_RS01605	COG1473	amidohydrolase
IEN91_RS01610	COG1288	antiporter activity
IEN91_RS01620	COG0366	Alpha amylase catalytic
IEN91_RS01630	COG2814	Major facilitator Superfamily
IEN91_RS01635	COG1846	Transcriptional regulator
IEN91_RS01640	COG1280	lysine exporter protein (LysE YggA)
IEN91_RS01645	COG3403	YqcI/YcgG family
IEN91_RS01650	COG1113	amino acid transport
IEN91_RS01655	COG3665	Urea carboxylase-associated protein
IEN91_RS01670	COG1660	Displays ATPase and GTPase activities
IEN91_RS01680	COG2271	Major facilitator Superfamily
IEN91_RS01685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IEN91_RS01690	COG3458	cephalosporin-C deacetylase activity
IEN91_RS01695	COG3541	Predicted nucleotidyltransferase
IEN91_RS01700	COG0506	proline dehydrogenase activity
IEN91_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
IEN91_RS01710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEN91_RS01715	COG2508	Transcriptional regulator
IEN91_RS01725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IEN91_RS01725	COG1587	Uroporphyrinogen-III synthase
IEN91_RS01730	COG2146	nitrite reductase [NAD(P)H] activity
IEN91_RS01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEN91_RS01745	COG1063	alcohol dehydrogenase
IEN91_RS01750	COG1714	RDD family
IEN91_RS01760	COG2723	6-phospho-beta-galactosidase activity
IEN91_RS01775	COG3209	COG3209 Rhs family protein
IEN91_RS01780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IEN91_RS01785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IEN91_RS01790	COG1733	regulation of RNA biosynthetic process
IEN91_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS01810	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IEN91_RS01825	COG2364	Membrane
IEN91_RS01830	COG1126	abc transporter atp-binding protein
IEN91_RS01835	COG0765	amino acid transport
IEN91_RS01840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEN91_RS01845	COG0583	DNA-binding transcription factor activity
IEN91_RS01850	COG0163	prenyltransferase activity
IEN91_RS01855	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IEN91_RS01870	COG3104	oligopeptide transport
IEN91_RS01875	COG5434	Belongs to the glycosyl hydrolase 28 family
IEN91_RS01885	COG0697	spore germination
IEN91_RS01895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IEN91_RS01900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEN91_RS01905	COG0456	acetyltransferase
IEN91_RS01910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEN91_RS01915	COG0765	amino acid transport
IEN91_RS01920	COG1126	abc transporter atp-binding protein
IEN91_RS01925	COG1473	amidohydrolase
IEN91_RS01930	COG2079	MmgE PrpD family protein
IEN91_RS01935	COG1136	(ABC) transporter
IEN91_RS01940	COG0577	efflux transmembrane transporter activity
IEN91_RS01945	COG0745	RESPONSE REGULATOR receiver
IEN91_RS01950	COG3850	Histidine kinase
IEN91_RS01950	COG5002	protein histidine kinase activity
IEN91_RS01955	COG0457	Tetratricopeptide repeat
IEN91_RS01970	COG0527	aspartate kinase activity
IEN91_RS01975	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEN91_RS01980	COG4605	iron ion homeostasis
IEN91_RS01985	COG4604	ABC transporter, ATP-binding protein
IEN91_RS01990	COG4607	ABC-type enterochelin transport system periplasmic component
IEN91_RS01995	COG2814	Major facilitator Superfamily
IEN91_RS02000	COG1309	transcriptional regulator
IEN91_RS02005	COG0778	Nitroreductase
IEN91_RS02010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IEN91_RS02015	COG0640	Transcriptional regulator
IEN91_RS02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEN91_RS02025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEN91_RS02030	COG1012	belongs to the aldehyde dehydrogenase family
IEN91_RS02035	COG4975	Glucose uptake
IEN91_RS02040	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS02045	COG4549	nuclear export factor GLE1
IEN91_RS02050	COG1276	copper resistance
IEN91_RS02050	COG2372	response to copper ion
IEN91_RS02055	COG1349	DNA-binding transcription factor activity
IEN91_RS02065	COG2213	PTS system mannitol-specific
IEN91_RS02070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEN91_RS02080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IEN91_RS02090	COG0561	phosphatase activity
IEN91_RS02100	COG1914	H( )-stimulated, divalent metal cation uptake system
IEN91_RS02110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IEN91_RS02115	COG1984	allophanate hydrolase subunit 2
IEN91_RS02120	COG1414	Transcriptional regulator
IEN91_RS02125	COG2755	lipolytic protein G-D-S-L family
IEN91_RS02135	COG2329	Antibiotic biosynthesis monooxygenase
IEN91_RS02140	COG0768	penicillin binding
IEN91_RS02145	COG4989	oxidoreductase activity
IEN91_RS02150	COG3711	transcriptional antiterminator
IEN91_RS02155	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS02165	COG1917	Cupin 2, conserved barrel domain protein
IEN91_RS02170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IEN91_RS02175	COG3871	stress protein (general stress protein 26)
IEN91_RS02185	COG2814	Major facilitator Superfamily
IEN91_RS02190	COG1522	sequence-specific DNA binding
IEN91_RS02195	COG0551	DNA topoisomerase type I activity
IEN91_RS02195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEN91_RS02200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IEN91_RS02205	COG3706	GGDEF domain
IEN91_RS02210	COG5298	Protein conserved in bacteria
IEN91_RS02215	COG1215	transferase activity, transferring glycosyl groups
IEN91_RS02225	COG0531	amino acid
IEN91_RS02230	COG0494	nUDIX hydrolase
IEN91_RS02235	COG0028	Belongs to the TPP enzyme family
IEN91_RS02315	COG1914	H( )-stimulated, divalent metal cation uptake system
IEN91_RS02325	COG4876	unkown
IEN91_RS02335	COG2076	Multidrug Resistance protein
IEN91_RS02340	COG2217	Heavy metal translocating P-type atpase
IEN91_RS02345	COG3729	General stress protein
IEN91_RS02350	COG0662	Cupin 2, conserved barrel domain protein
IEN91_RS02355	COG2329	Antibiotic biosynthesis monooxygenase
IEN91_RS02360	COG3546	catalase activity
IEN91_RS02365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IEN91_RS02370	COG3290	protein histidine kinase activity
IEN91_RS02375	COG4565	transcriptional regulatory protein
IEN91_RS02380	COG1301	dicarboxylic acid transport
IEN91_RS02385	COG0628	permease
IEN91_RS02390	COG1131	(ABC) transporter
IEN91_RS02395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IEN91_RS02405	COG1960	acyl-CoA dehydrogenase activity
IEN91_RS02420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEN91_RS02425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IEN91_RS02435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IEN91_RS02440	COG0513	Belongs to the DEAD box helicase family
IEN91_RS02445	COG3402	PFAM membrane-flanked domain
IEN91_RS02450	COG3428	Bacterial PH domain
IEN91_RS02455	COG0705	Rhomboid family
IEN91_RS02465	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IEN91_RS02470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEN91_RS02475	COG0864	Transcriptional regulator
IEN91_RS02480	COG2337	Toxic component of a toxin-antitoxin (TA) module
IEN91_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
IEN91_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
IEN91_RS02495	COG2172	sigma factor antagonist activity
IEN91_RS02500	COG2208	phosphoserine phosphatase activity
IEN91_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
IEN91_RS02515	COG1191	sigma factor activity
IEN91_RS02520	COG2208	phosphoserine phosphatase activity
IEN91_RS02525	COG2183	response to ionizing radiation
IEN91_RS02575	COG0457	Tetratricopeptide repeat
IEN91_RS02580	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEN91_RS02595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IEN91_RS02600	COG0477	Major facilitator Superfamily
IEN91_RS02610	COG1764	response to oxidative stress
IEN91_RS02615	COG1846	Transcriptional regulator
IEN91_RS02625	COG1959	2 iron, 2 sulfur cluster binding
IEN91_RS02630	COG2910	NAD(P)H-binding
IEN91_RS02635	COG1278	Cold shock
IEN91_RS02645	COG1937	Protein conserved in bacteria
IEN91_RS02650	COG2210	Belongs to the sulfur carrier protein TusA family
IEN91_RS02660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IEN91_RS02660	COG0425	Belongs to the sulfur carrier protein TusA family
IEN91_RS02665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEN91_RS02665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IEN91_RS02670	COG0425	Belongs to the sulfur carrier protein TusA family
IEN91_RS02675	COG0730	response to heat
IEN91_RS02680	COG1794	racemase activity, acting on amino acids and derivatives
IEN91_RS02695	COG3621	Patatin-like phospholipase
IEN91_RS02705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IEN91_RS02710	COG1802	Transcriptional regulator
IEN91_RS02715	COG0251	oxidation-reduction process
IEN91_RS02720	COG0814	amino acid
IEN91_RS02725	COG1473	amidohydrolase
IEN91_RS02730	COG1917	Cupin 2, conserved barrel domain protein
IEN91_RS02730	COG2207	Transcriptional regulator
IEN91_RS02740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEN91_RS02765	COG0277	FAD linked oxidase domain protein
IEN91_RS02790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEN91_RS02815	COG1064	alcohol dehydrogenase
IEN91_RS02820	COG0789	Transcriptional regulator
IEN91_RS02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEN91_RS02845	COG2814	Major facilitator Superfamily
IEN91_RS02850	COG1309	transcriptional regulator
IEN91_RS02855	COG5577	PFAM Coat F domain
IEN91_RS02865	COG1063	alcohol dehydrogenase
IEN91_RS02870	COG5577	PFAM Coat F domain
IEN91_RS02880	COG4585	Histidine kinase
IEN91_RS02885	COG2197	response regulator
IEN91_RS02890	COG2409	Drug exporters of the RND superfamily
IEN91_RS02895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IEN91_RS02900	COG0488	(ABC) transporter
IEN91_RS02905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IEN91_RS02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEN91_RS02925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IEN91_RS02935	COG0730	response to heat
IEN91_RS02940	COG0456	acetyltransferase
IEN91_RS02945	COG4978	Transcriptional regulator
IEN91_RS02945	COG0789	Transcriptional regulator
IEN91_RS02950	COG0697	spore germination
IEN91_RS02955	COG1051	belongs to the nudix hydrolase family
IEN91_RS02960	COG2226	methyltransferase
IEN91_RS02965	COG0473	3-isopropylmalate dehydrogenase activity
IEN91_RS02970	COG1802	Transcriptional regulator
IEN91_RS02975	COG1819	glycosyl
IEN91_RS02990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IEN91_RS03000	COG1388	LysM domain
IEN91_RS03005	COG2814	Major facilitator Superfamily
IEN91_RS03010	COG2188	Transcriptional regulator
IEN91_RS03015	COG2186	Transcriptional regulator
IEN91_RS03020	COG2807	transmembrane transport
IEN91_RS03025	COG2076	Multidrug Resistance protein
IEN91_RS03030	COG2076	Multidrug Resistance protein
IEN91_RS03035	COG1309	transcriptional regulator
IEN91_RS03040	COG0531	amino acid
IEN91_RS03050	COG3832	glyoxalase III activity
IEN91_RS03055	COG0604	alcohol dehydrogenase
IEN91_RS03060	COG2814	Major facilitator Superfamily
IEN91_RS03100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IEN91_RS03105	COG0802	atpase or kinase
IEN91_RS03110	COG1214	PFAM Peptidase M22, glycoprotease
IEN91_RS03115	COG0456	acetyltransferase
IEN91_RS03120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IEN91_RS03125	COG0488	(ABC) transporter
IEN91_RS03140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IEN91_RS03145	COG0805	protein transport
IEN91_RS03155	COG1266	CAAX protease self-immunity
IEN91_RS03175	COG0457	Tetratricopeptide repeat
IEN91_RS03180	COG1063	alcohol dehydrogenase
IEN91_RS03185	COG2211	Major facilitator Superfamily
IEN91_RS03190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEN91_RS03200	COG1842	Phage shock protein A
IEN91_RS03205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEN91_RS03210	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IEN91_RS03215	COG4260	virion core protein, lumpy skin disease virus
IEN91_RS03220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IEN91_RS03220	COG2755	lipolytic protein G-D-S-L family
IEN91_RS03230	COG1595	DNA-templated transcription, initiation
IEN91_RS03235	COG1063	alcohol dehydrogenase
IEN91_RS03240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IEN91_RS03245	COG0823	Involved in the tonB-independent uptake of proteins
IEN91_RS03260	COG2132	Multicopper oxidase
IEN91_RS03265	COG1113	amino acid transport
IEN91_RS03270	COG0714	Associated with various cellular activities
IEN91_RS03275	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
IEN91_RS03280	COG1305	Transglutaminase-like
IEN91_RS03300	COG2252	PERMEase
IEN91_RS03305	COG3064	Membrane
IEN91_RS03325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IEN91_RS03330	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IEN91_RS03335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IEN91_RS03340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IEN91_RS03345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEN91_RS03360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IEN91_RS03370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IEN91_RS03375	COG0138	bifunctional purine biosynthesis protein purh
IEN91_RS03380	COG0151	Belongs to the GarS family
IEN91_RS03390	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IEN91_RS03395	COG1470	cell adhesion involved in biofilm formation
IEN91_RS03400	COG4496	protein, YerC YecD
IEN91_RS03405	COG0069	glutamate synthase activity
IEN91_RS03415	COG0210	DNA helicase
IEN91_RS03425	COG4851	CamS sex pheromone cAM373 precursor
IEN91_RS03430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IEN91_RS03435	COG1285	pathogenesis
IEN91_RS03440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEN91_RS03460	COG1309	transcriptional regulator
IEN91_RS03465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IEN91_RS03470	COG1597	lipid kinase activity
IEN91_RS03475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEN91_RS03530	COG5444	nuclease activity
IEN91_RS03565	COG3546	catalase activity
IEN91_RS03570	COG0454	-acetyltransferase
IEN91_RS03580	COG2323	membrane
IEN91_RS03585	COG2329	Antibiotic biosynthesis monooxygenase
IEN91_RS03590	COG0346	lactoylglutathione lyase activity
IEN91_RS03595	COG1366	Belongs to the anti-sigma-factor antagonist family
IEN91_RS03600	COG5583	Uncharacterized small protein (DUF2292)
IEN91_RS03605	COG0196	riboflavin kinase activity
IEN91_RS03610	COG0670	Belongs to the BI1 family
IEN91_RS03620	COG1846	Transcriptional regulator
IEN91_RS03625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEN91_RS03635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IEN91_RS03635	COG2124	cytochrome p450
IEN91_RS03640	COG1368	sulfuric ester hydrolase activity
IEN91_RS03645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IEN91_RS03650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IEN91_RS03655	COG1442	glycosyl transferase family 8
IEN91_RS03660	COG1216	Glycosyl transferase, family 2
IEN91_RS03665	COG1442	glycosyl transferase family 8
IEN91_RS03670	COG2223	nitrite transmembrane transporter activity
IEN91_RS03675	COG0531	amino acid
IEN91_RS03680	COG1012	belongs to the aldehyde dehydrogenase family
IEN91_RS03685	COG0840	transmembrane signaling receptor activity
IEN91_RS03690	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS03695	COG0463	Glycosyl transferase, family 2
IEN91_RS03695	COG0457	Tetratricopeptide repeat
IEN91_RS03700	COG0488	(ABC) transporter
IEN91_RS03705	COG0789	Transcriptional regulator
IEN91_RS03710	COG2814	Major facilitator Superfamily
IEN91_RS03715	COG0488	(ABC) transporter
IEN91_RS03720	COG0513	Belongs to the DEAD box helicase family
IEN91_RS03730	COG2130	NADP-dependent
IEN91_RS03745	COG3866	Pectate lyase
IEN91_RS03750	COG0471	metal ion transport
IEN91_RS03770	COG3290	protein histidine kinase activity
IEN91_RS03775	COG4565	transcriptional regulatory protein
IEN91_RS03780	COG3181	Tripartite tricarboxylate transporter family receptor
IEN91_RS03785	COG2851	Citrate transporter
IEN91_RS03790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEN91_RS03795	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IEN91_RS03805	COG2258	MOSC domain
IEN91_RS03825	COG0024	Methionine aminopeptidase
IEN91_RS03830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IEN91_RS03830	COG1263	PTS System
IEN91_RS03840	COG1368	sulfuric ester hydrolase activity
IEN91_RS03850	COG0071	Belongs to the small heat shock protein (HSP20) family
IEN91_RS03865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IEN91_RS03865	COG1263	PTS System
IEN91_RS03870	COG0366	Alpha amylase catalytic
IEN91_RS03875	COG2188	Transcriptional regulator
IEN91_RS03880	COG0778	Nitroreductase
IEN91_RS03895	COG0737	Belongs to the 5'-nucleotidase family
IEN91_RS03900	COG0693	protein deglycase activity
IEN91_RS03905	COG1609	Transcriptional regulator
IEN91_RS03920	COG2814	Major facilitator Superfamily
IEN91_RS03930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEN91_RS03935	COG4980	gas vesicle protein
IEN91_RS03940	COG1295	ribonuclease BN
IEN91_RS03945	COG0477	Major facilitator Superfamily
IEN91_RS03950	COG0387	Pfam Sodium calcium exchanger
IEN91_RS03960	COG0668	transmembrane transport
IEN91_RS03965	COG0535	radical SAM domain protein
IEN91_RS03975	COG0726	polysaccharide deacetylase
IEN91_RS03980	COG2084	Dehydrogenase
IEN91_RS03990	COG0598	Magnesium transport protein CorA
IEN91_RS03995	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IEN91_RS04000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEN91_RS04010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEN91_RS04015	COG4637	Psort location Cytoplasmic, score
IEN91_RS04020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IEN91_RS04025	COG0022	dehydrogenase e1 component
IEN91_RS04030	COG0508	dehydrogenase complex catalyzes the overall conversion of
IEN91_RS04035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEN91_RS04040	COG3284	Transcriptional regulator
IEN91_RS04050	COG1486	melibiose metabolic process
IEN91_RS04055	COG1737	Transcriptional regulator
IEN91_RS04060	COG1263	PTS System
IEN91_RS04060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IEN91_RS04065	COG1132	(ABC) transporter
IEN91_RS04070	COG1132	(ABC) transporter
IEN91_RS04075	COG2259	Doxx family
IEN91_RS04080	COG2514	catechol 2,3-dioxygenase activity
IEN91_RS04090	COG1695	Transcriptional regulator
IEN91_RS04095	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEN91_RS04100	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IEN91_RS04105	COG3848	Pyruvate phosphate dikinase
IEN91_RS04105	COG0574	Belongs to the PEP-utilizing enzyme family
IEN91_RS04110	COG2732	(Barnase) inhibitor
IEN91_RS04115	COG2318	DinB family
IEN91_RS04120	COG2814	Major facilitator Superfamily
IEN91_RS04125	COG1846	Transcriptional regulator
IEN91_RS04130	COG0392	lysyltransferase activity
IEN91_RS04130	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IEN91_RS04135	COG0384	phenazine biosynthesis protein PhzF
IEN91_RS04140	COG0778	Nitroreductase
IEN91_RS04155	COG1090	epimerase
IEN91_RS04170	COG2814	Major facilitator Superfamily
IEN91_RS04180	COG3591	Belongs to the peptidase S1B family
IEN91_RS04195	COG3103	Sh3 type 3 domain protein
IEN91_RS04200	COG5658	integral membrane protein
IEN91_RS04205	COG0596	Alpha beta hydrolase
IEN91_RS04210	COG0463	Glycosyl transferase, family 2
IEN91_RS04215	COG4485	Bacterial membrane protein, YfhO
IEN91_RS04220	COG1988	membrane-bound metal-dependent
IEN91_RS04225	COG1194	a g-specific adenine glycosylase
IEN91_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS04255	COG1132	(ABC) transporter
IEN91_RS04260	COG4129	membrane
IEN91_RS04270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IEN91_RS04275	COG0735	belongs to the Fur family
IEN91_RS04385	COG4974	Belongs to the 'phage' integrase family
IEN91_RS04445	COG1435	thymidine kinase activity
IEN91_RS04455	COG0587	DNA-directed DNA polymerase activity
IEN91_RS04495	COG2247	cell wall binding repeat
IEN91_RS04495	COG0860	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS04520	COG2433	Pfam Transposase IS66
IEN91_RS04535	COG0741	lytic transglycosylase activity
IEN91_RS04535	COG1196	nuclear chromosome segregation
IEN91_RS04535	COG0739	heme binding
IEN91_RS04540	COG4974	Belongs to the 'phage' integrase family
IEN91_RS04620	COG3420	alginic acid biosynthetic process
IEN91_RS04620	COG5434	Belongs to the glycosyl hydrolase 28 family
IEN91_RS04700	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IEN91_RS04730	COG0582	viral genome integration into host DNA
IEN91_RS04735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IEN91_RS04750	COG4195	phage-related replication protein
IEN91_RS04845	COG2195	Cleaves the N-terminal amino acid of tripeptides
IEN91_RS04990	COG1216	Glycosyl transferase, family 2
IEN91_RS04995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IEN91_RS05005	COG0457	Tetratricopeptide repeat
IEN91_RS05260	COG4474	Belongs to the UPF0398 family
IEN91_RS05345	COG3584	3D domain protein
IEN91_RS05350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IEN91_RS05375	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IEN91_RS05375	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IEN91_RS05395	COG0328	RNA-DNA hybrid ribonuclease activity
IEN91_RS05415	COG0187	DNA topoisomerase II activity
IEN91_RS05420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEN91_RS05440	COG1780	Probably involved in ribonucleotide reductase function
IEN91_RS05445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEN91_RS05450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEN91_RS05470	COG0194	GDP metabolic process
IEN91_RS05480	COG0484	heat shock protein binding
IEN91_RS05490	COG1404	Belongs to the peptidase S8 family
IEN91_RS05495	COG0085	RNA polymerase activity
IEN91_RS05510	COG3285	dna ligase
IEN91_RS05510	COG1793	dna ligase
IEN91_RS05535	COG3340	Belongs to the peptidase S51 family
IEN91_RS05545	COG0277	FAD linked oxidase domain protein
IEN91_RS05555	COG0747	negative chemotaxis
IEN91_RS05560	COG0601	transmembrane transport
IEN91_RS05565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEN91_RS05570	COG0444	Belongs to the ABC transporter superfamily
IEN91_RS05575	COG4608	Belongs to the ABC transporter superfamily
IEN91_RS05580	COG0753	catalase activity
IEN91_RS05590	COG1116	anion transmembrane transporter activity
IEN91_RS05595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEN91_RS05600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IEN91_RS05620	COG1476	TRANSCRIPTIONal
IEN91_RS05630	COG3382	B3 4 domain protein
IEN91_RS05635	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IEN91_RS05645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IEN91_RS05650	COG0789	Transcriptional regulator
IEN91_RS05655	COG1664	Polymer-forming cytoskeletal
IEN91_RS05660	COG1664	Polymer-forming cytoskeletal
IEN91_RS05665	COG2766	serine protein kinase
IEN91_RS05675	COG1846	Transcriptional regulator
IEN91_RS05680	COG1566	PFAM secretion protein HlyD family protein
IEN91_RS05685	COG2814	Major facilitator Superfamily
IEN91_RS05690	COG0655	NAD(P)H dehydrogenase (quinone) activity
IEN91_RS05705	COG1725	Transcriptional regulator
IEN91_RS05710	COG1131	(ABC) transporter
IEN91_RS05715	COG1131	(ABC) transporter
IEN91_RS05720	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IEN91_RS05725	COG1278	Cold shock
IEN91_RS05730	COG1464	Belongs to the NlpA lipoprotein family
IEN91_RS05735	COG3706	GGDEF domain
IEN91_RS05740	COG1823	symporter activity
IEN91_RS05760	COG5577	PFAM Coat F domain
IEN91_RS05765	COG4085	toxin activity
IEN91_RS05765	COG0737	Belongs to the 5'-nucleotidase family
IEN91_RS05765	COG1525	nuclease
IEN91_RS05770	COG3764	Sortase (surface protein transpeptidase)
IEN91_RS05775	COG0564	pseudouridine synthase activity
IEN91_RS05785	COG0517	IMP dehydrogenase activity
IEN91_RS05790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IEN91_RS05795	COG3153	acetyltransferase
IEN91_RS05795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IEN91_RS05800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IEN91_RS05805	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IEN91_RS05810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IEN91_RS05820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IEN91_RS05825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEN91_RS05840	COG0431	NADPH-dependent FMN reductase
IEN91_RS05855	COG0791	NLP P60 protein
IEN91_RS05855	COG1388	LysM domain
IEN91_RS05860	COG1959	2 iron, 2 sulfur cluster binding
IEN91_RS05865	COG0668	transmembrane transport
IEN91_RS05870	COG2719	SpoVR family
IEN91_RS05875	COG1785	Belongs to the alkaline phosphatase family
IEN91_RS05880	COG1388	LysM domain
IEN91_RS05880	COG0791	NLP P60 protein
IEN91_RS05885	COG0583	DNA-binding transcription factor activity
IEN91_RS05890	COG0372	Belongs to the citrate synthase family
IEN91_RS05895	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS05900	COG0531	amino acid
IEN91_RS05905	COG0733	neurotransmitter:sodium symporter activity
IEN91_RS05920	COG1595	DNA-templated transcription, initiation
IEN91_RS05925	COG0204	Acyl-transferase
IEN91_RS05930	COG1253	flavin adenine dinucleotide binding
IEN91_RS05935	COG0789	Transcriptional regulator
IEN91_RS05940	COG0436	Aminotransferase
IEN91_RS05945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IEN91_RS05950	COG1253	flavin adenine dinucleotide binding
IEN91_RS05955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEN91_RS05960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEN91_RS05965	COG0584	glycerophosphoryl diester phosphodiesterase
IEN91_RS05975	COG0668	transmembrane transport
IEN91_RS05980	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IEN91_RS05985	COG0726	polysaccharide deacetylase
IEN91_RS05990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IEN91_RS05995	COG3226	Transcriptional regulator
IEN91_RS06005	COG0589	response to stress
IEN91_RS06010	COG1132	(ABC) transporter
IEN91_RS06015	COG1132	(ABC) transporter
IEN91_RS06020	COG0702	epimerase
IEN91_RS06035	COG0189	ligase activity
IEN91_RS06040	COG0189	ligase activity
IEN91_RS06055	COG4335	DNA alkylation repair
IEN91_RS06060	COG0561	phosphatase activity
IEN91_RS06065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IEN91_RS06075	COG0475	glutathione-regulated potassium exporter activity
IEN91_RS06080	COG0490	domain, Protein
IEN91_RS06090	COG1024	Enoyl-CoA hydratase
IEN91_RS06100	COG4152	abc transporter atp-binding protein
IEN91_RS06105	COG1668	transmembrane transport
IEN91_RS06110	COG0420	3'-5' exonuclease activity
IEN91_RS06115	COG4717	serine-type aminopeptidase activity
IEN91_RS06130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IEN91_RS06165	COG4980	gas vesicle protein
IEN91_RS06180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IEN91_RS06185	COG0537	adenosine 5'-monophosphoramidase activity
IEN91_RS06190	COG1131	(ABC) transporter
IEN91_RS06195	COG4473	ABC transporter
IEN91_RS06205	COG1473	amidohydrolase
IEN91_RS06210	COG3069	C4-dicarboxylate transmembrane transporter activity
IEN91_RS06215	COG2329	Antibiotic biosynthesis monooxygenase
IEN91_RS06220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IEN91_RS06230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IEN91_RS06235	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IEN91_RS06240	COG1309	transcriptional regulator
IEN91_RS06245	COG1511	domain protein
IEN91_RS06250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEN91_RS06260	COG1363	Peptidase, m42
IEN91_RS06265	COG1301	dicarboxylic acid transport
IEN91_RS06275	COG1234	tRNA 3'-trailer cleavage
IEN91_RS06280	COG0095	Lipoate-protein ligase
IEN91_RS06285	COG0702	epimerase
IEN91_RS06290	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS06300	COG0501	Belongs to the peptidase M48B family
IEN91_RS06305	COG1404	Belongs to the peptidase S8 family
IEN91_RS06310	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IEN91_RS06315	COG0406	alpha-ribazole phosphatase activity
IEN91_RS06320	COG0183	Belongs to the thiolase family
IEN91_RS06325	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS06330	COG1268	BioY protein
IEN91_RS06335	COG0840	transmembrane signaling receptor activity
IEN91_RS06340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IEN91_RS06340	COG0723	plastoquinol--plastocyanin reductase activity
IEN91_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS06355	COG4903	ComK protein
IEN91_RS06365	COG5646	InterPro IPR014922
IEN91_RS06385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEN91_RS06400	COG0398	Pfam SNARE associated Golgi protein
IEN91_RS06405	COG0681	Belongs to the peptidase S26 family
IEN91_RS06410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEN91_RS06415	COG1846	Transcriptional regulator
IEN91_RS06420	COG3180	Ammonia monooxygenase
IEN91_RS06425	COG2814	Major facilitator Superfamily
IEN91_RS06435	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IEN91_RS06440	COG2323	membrane
IEN91_RS06455	COG0420	3'-5' exonuclease activity
IEN91_RS06460	COG0419	ATPase involved in DNA repair
IEN91_RS06465	COG1403	HNH endonuclease
IEN91_RS06505	COG0179	Fumarylacetoacetate (FAA) hydrolase
IEN91_RS06525	COG0367	asparagine synthase
IEN91_RS06530	COG1562	ergosterol biosynthetic process
IEN91_RS06535	COG0534	Mate efflux family protein
IEN91_RS06540	COG2207	Transcriptional regulator
IEN91_RS06540	COG1917	Cupin 2, conserved barrel domain protein
IEN91_RS06545	COG1609	Transcriptional regulator
IEN91_RS06550	COG0673	inositol 2-dehydrogenase activity
IEN91_RS06555	COG2318	DinB family
IEN91_RS06560	COG1357	PFAM Pentapeptide repeats (8 copies)
IEN91_RS06565	COG2153	protein acetylation
IEN91_RS06570	COG0646	methionine synthase
IEN91_RS06570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IEN91_RS06580	COG2996	Protein conserved in bacteria
IEN91_RS06585	COG1744	ABC transporter substrate-binding protein PnrA-like
IEN91_RS06590	COG0840	transmembrane signaling receptor activity
IEN91_RS06600	COG1307	EDD domain protein, DegV family
IEN91_RS06605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEN91_RS06625	COG0561	phosphatase activity
IEN91_RS06630	COG1073	alpha beta
IEN91_RS06635	COG2151	metal-sulfur cluster biosynthetic enzyme
IEN91_RS06645	COG0277	FAD linked oxidase domain protein
IEN91_RS06650	COG2271	Major facilitator Superfamily
IEN91_RS06660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IEN91_RS06670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IEN91_RS06675	COG0505	Belongs to the CarA family
IEN91_RS06680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IEN91_RS06685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IEN91_RS06700	COG2267	carboxylic ester hydrolase activity
IEN91_RS06710	COG1744	ABC transporter substrate-binding protein PnrA-like
IEN91_RS06725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEN91_RS06730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IEN91_RS06735	COG5504	Zn-dependent protease
IEN91_RS06740	COG0444	Belongs to the ABC transporter superfamily
IEN91_RS06745	COG4608	Belongs to the ABC transporter superfamily
IEN91_RS06755	COG0601	transmembrane transport
IEN91_RS06760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEN91_RS06780	COG0180	Tryptophanyl-tRNA synthetase
IEN91_RS06785	COG4166	transmembrane transport
IEN91_RS06790	COG0601	transmembrane transport
IEN91_RS06795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEN91_RS06805	COG4608	Belongs to the ABC transporter superfamily
IEN91_RS06815	COG0456	acetyltransferase
IEN91_RS06820	COG1393	Belongs to the ArsC family
IEN91_RS06825	COG0861	Integral membrane protein TerC family
IEN91_RS06835	COG4862	establishment of competence for transformation
IEN91_RS06840	COG4469	Competence protein
IEN91_RS06845	COG1164	Oligoendopeptidase f
IEN91_RS06855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IEN91_RS06860	COG2346	COG2346, Truncated hemoglobins
IEN91_RS06865	COG0741	lytic transglycosylase activity
IEN91_RS06870	COG4116	CYTH
IEN91_RS06880	COG2357	RelA SpoT domain protein
IEN91_RS06885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEN91_RS06890	COG0564	pseudouridine synthase activity
IEN91_RS06900	COG0475	glutathione-regulated potassium exporter activity
IEN91_RS06900	COG0569	domain protein
IEN91_RS06905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IEN91_RS06910	COG0352	thiamine-phosphate diphosphorylase activity
IEN91_RS06915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IEN91_RS06920	COG2104	thiamine diphosphate biosynthetic process
IEN91_RS06930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IEN91_RS06935	COG0351	phosphomethylpyrimidine kinase
IEN91_RS06940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IEN91_RS06995	COG0210	DNA helicase
IEN91_RS07015	COG1131	(ABC) transporter
IEN91_RS07025	COG2153	protein acetylation
IEN91_RS07035	COG2382	esterase
IEN91_RS07040	COG0626	cystathionine gamma-synthase activity
IEN91_RS07045	COG0626	cystathionine gamma-synthase activity
IEN91_RS07060	COG5444	nuclease activity
IEN91_RS07070	COG0346	lactoylglutathione lyase activity
IEN91_RS07075	COG2367	Beta-lactamase
IEN91_RS07080	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IEN91_RS07090	COG1846	Transcriptional regulator
IEN91_RS07100	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IEN91_RS07105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IEN91_RS07110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IEN91_RS07115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IEN91_RS07115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IEN91_RS07120	COG1447	Phosphotransferase system cellobiose-specific component IIA
IEN91_RS07130	COG1349	DNA-binding transcription factor activity
IEN91_RS07145	COG1285	pathogenesis
IEN91_RS07155	COG2205	protein histidine kinase activity
IEN91_RS07165	COG3383	formate dehydrogenase (NAD+) activity
IEN91_RS07170	COG2427	Protein of unknown function (DUF1641)
IEN91_RS07175	COG2124	cytochrome p450
IEN91_RS07180	COG1819	glycosyl
IEN91_RS07190	COG1587	Uroporphyrinogen-III synthase
IEN91_RS07195	COG0390	transport system, permease component
IEN91_RS07200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IEN91_RS07205	COG0697	spore germination
IEN91_RS07210	COG4297	protein containing double-stranded beta helix domain
IEN91_RS07220	COG1252	NADH dehydrogenase
IEN91_RS07230	COG2211	Major facilitator Superfamily
IEN91_RS07235	COG1609	Transcriptional regulator
IEN91_RS07240	COG0246	Mannitol dehydrogenase
IEN91_RS07245	COG2721	sulfolactate sulfo-lyase activity
IEN91_RS07250	COG0745	RESPONSE REGULATOR receiver
IEN91_RS07255	COG2770	Histidine kinase
IEN91_RS07255	COG2205	protein histidine kinase activity
IEN91_RS07270	COG0730	response to heat
IEN91_RS07275	COG2318	DinB family
IEN91_RS07280	COG0457	Tetratricopeptide repeat
IEN91_RS07290	COG5632	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS07290	COG1388	LysM domain
IEN91_RS07290	COG3409	Peptidoglycan-binding domain 1 protein
IEN91_RS07300	COG4195	phage-related replication protein
IEN91_RS07310	COG2856	Zn peptidase
IEN91_RS07315	COG1396	sequence-specific DNA binding
IEN91_RS07325	COG1522	sequence-specific DNA binding
IEN91_RS07330	COG1484	DNA-dependent DNA replication
IEN91_RS07350	COG1595	DNA-templated transcription, initiation
IEN91_RS07355	COG5484	DNA packaging
IEN91_RS07355	COG3728	DNA packaging
IEN91_RS07360	COG1783	phage Terminase large subunit
IEN91_RS07365	COG5518	Phage portal protein
IEN91_RS07370	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IEN91_RS07375	COG4653	Phage capsid family
IEN91_RS07425	COG5412	phage tail tape measure protein
IEN91_RS07425	COG3953	SLT domain
IEN91_RS07425	COG5412	phage tail tape measure protein
IEN91_RS07425	COG3953	SLT domain
IEN91_RS07425	COG3953	SLT domain
IEN91_RS07425	COG5412	phage tail tape measure protein
IEN91_RS07430	COG1652	LysM domain
IEN91_RS07435	COG4193	domain, Protein
IEN91_RS07445	COG3628	GPW Gp25 family protein
IEN91_RS07450	COG3299	homolog of phage Mu protein gp47
IEN91_RS07455	COG3778	Protein conserved in bacteria
IEN91_RS07495	COG3409	Peptidoglycan-binding domain 1 protein
IEN91_RS07495	COG5632	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS07510	COG0306	phosphate transporter
IEN91_RS07515	COG1392	Phosphate transport regulator
IEN91_RS07520	COG0531	amino acid
IEN91_RS07525	COG0346	lactoylglutathione lyase activity
IEN91_RS07530	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IEN91_RS07535	COG0463	Glycosyl transferase, family 2
IEN91_RS07545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEN91_RS07550	COG0477	Major facilitator Superfamily
IEN91_RS07555	COG2362	D-Aminopeptidase
IEN91_RS07560	COG0601	transmembrane transport
IEN91_RS07565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEN91_RS07570	COG0444	Belongs to the ABC transporter superfamily
IEN91_RS07575	COG4166	transmembrane transport
IEN91_RS07580	COG1619	proteins homologs of microcin C7 resistance protein MccF
IEN91_RS07585	COG4948	Mandelate Racemase Muconate Lactonizing
IEN91_RS07590	COG0791	NLP P60 protein
IEN91_RS07595	COG4608	Belongs to the ABC transporter superfamily
IEN91_RS07600	COG2706	6-phosphogluconolactonase activity
IEN91_RS07605	COG1834	amidinotransferase
IEN91_RS07610	COG1607	acyl-coa hydrolase
IEN91_RS07615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IEN91_RS07620	COG2076	Multidrug Resistance protein
IEN91_RS07625	COG2076	Multidrug Resistance protein
IEN91_RS07630	COG0788	formyltetrahydrofolate deformylase activity
IEN91_RS07635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IEN91_RS07645	COG1764	response to oxidative stress
IEN91_RS07650	COG1846	Transcriptional regulator
IEN91_RS07655	COG1764	response to oxidative stress
IEN91_RS07670	COG0463	Glycosyl transferase, family 2
IEN91_RS07670	COG0457	Tetratricopeptide repeat
IEN91_RS07680	COG2814	Major facilitator Superfamily
IEN91_RS07685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IEN91_RS07695	COG1404	Belongs to the peptidase S8 family
IEN91_RS07700	COG1366	Belongs to the anti-sigma-factor antagonist family
IEN91_RS07705	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEN91_RS07710	COG1122	ATPase activity
IEN91_RS07715	COG4721	ABC-type cobalt transport system, permease component
IEN91_RS07720	COG1388	LysM domain
IEN91_RS07720	COG3858	chitin binding
IEN91_RS07730	COG2239	Acts as a magnesium transporter
IEN91_RS07735	COG0789	Transcriptional regulator
IEN91_RS07750	COG1846	Transcriptional regulator
IEN91_RS07755	COG0726	polysaccharide deacetylase
IEN91_RS07760	COG1793	dna ligase
IEN91_RS07760	COG3285	dna ligase
IEN91_RS07765	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IEN91_RS07770	COG0586	Pfam SNARE associated Golgi protein
IEN91_RS07775	COG0861	Integral membrane protein TerC family
IEN91_RS07780	COG1191	sigma factor activity
IEN91_RS07805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IEN91_RS07810	COG2323	membrane
IEN91_RS07820	COG3594	Acyltransferase
IEN91_RS07825	COG5002	protein histidine kinase activity
IEN91_RS07830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEN91_RS07845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IEN91_RS07850	COG0436	Aminotransferase
IEN91_RS07880	COG3852	Histidine kinase
IEN91_RS07885	COG1846	Transcriptional regulator
IEN91_RS07890	COG1360	Flagellar Motor Protein
IEN91_RS07895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IEN91_RS07900	COG0542	response to heat
IEN91_RS07905	COG3949	Membrane
IEN91_RS07920	COG0720	synthase
IEN91_RS07925	COG0602	queuosine metabolic process
IEN91_RS07970	COG4873	Protein conserved in bacteria
IEN91_RS07980	COG3773	Cell wall hydrolase
IEN91_RS07985	COG2244	polysaccharide biosynthetic process
IEN91_RS07990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IEN91_RS07995	COG2217	Heavy metal translocating P-type atpase
IEN91_RS08000	COG0006	proline dipeptidase activity
IEN91_RS08005	COG1609	Transcriptional regulator
IEN91_RS08010	COG3711	transcriptional antiterminator
IEN91_RS08015	COG1263	PTS System
IEN91_RS08015	COG2190	(PTS) system
IEN91_RS08015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IEN91_RS08020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEN91_RS08025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IEN91_RS08035	COG1533	DNA photolyase activity
IEN91_RS08040	COG0840	transmembrane signaling receptor activity
IEN91_RS08045	COG2084	Dehydrogenase
IEN91_RS08050	COG2340	Cysteine-rich secretory protein family
IEN91_RS08055	COG0768	penicillin binding
IEN91_RS08060	COG4191	Histidine kinase
IEN91_RS08065	COG0436	Aminotransferase
IEN91_RS08075	COG0835	chemotaxis
IEN91_RS08075	COG0784	Response regulator, receiver
IEN91_RS08085	COG2814	Major facilitator Superfamily
IEN91_RS08090	COG1376	ErfK ybiS ycfS ynhG family protein
IEN91_RS08095	COG1408	metallophosphoesterase
IEN91_RS08100	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS08110	COG2200	EAL domain
IEN91_RS08115	COG4703	Protein of unknown function (DUF1797)
IEN91_RS08120	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
IEN91_RS08130	COG0517	IMP dehydrogenase activity
IEN91_RS08135	COG0583	DNA-binding transcription factor activity
IEN91_RS08140	COG0716	FMN binding
IEN91_RS08150	COG0716	FMN binding
IEN91_RS08170	COG0668	transmembrane transport
IEN91_RS08175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IEN91_RS08195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IEN91_RS08200	COG0303	'Molybdopterin
IEN91_RS08205	COG1763	Mo-molybdopterin cofactor biosynthetic process
IEN91_RS08210	COG0314	molybdopterin synthase activity
IEN91_RS08215	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IEN91_RS08225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEN91_RS08230	COG1136	(ABC) transporter
IEN91_RS08235	COG0577	efflux transmembrane transporter activity
IEN91_RS08240	COG1349	DNA-binding transcription factor activity
IEN91_RS08245	COG1105	Belongs to the carbohydrate kinase PfkB family
IEN91_RS08250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEN91_RS08250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IEN91_RS08250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IEN91_RS08255	COG0681	Belongs to the peptidase S26 family
IEN91_RS08265	COG0488	(ABC) transporter
IEN91_RS08270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IEN91_RS08275	COG2309	aminopeptidase activity
IEN91_RS08285	COG1077	Cell shape determining protein MreB Mrl
IEN91_RS08290	COG2002	toxin-antitoxin pair type II binding
IEN91_RS08295	COG3852	Histidine kinase
IEN91_RS08300	COG2105	PFAM AIG2 family protein
IEN91_RS08300	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IEN91_RS08305	COG0569	domain protein
IEN91_RS08315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEN91_RS08325	COG0561	phosphatase activity
IEN91_RS08330	COG0242	peptide deformylase activity
IEN91_RS08340	COG0497	DNA recombination
IEN91_RS08350	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS08350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS08350	COG3321	synthase
IEN91_RS08350	COG4221	oxidoreductase activity
IEN91_RS08355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS08355	COG4221	oxidoreductase activity
IEN91_RS08355	COG0300	oxidoreductase activity
IEN91_RS08355	COG3321	synthase
IEN91_RS08360	COG4221	oxidoreductase activity
IEN91_RS08360	COG3321	synthase
IEN91_RS08360	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS08360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS08365	COG4221	oxidoreductase activity
IEN91_RS08365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS08365	COG0300	oxidoreductase activity
IEN91_RS08365	COG3321	synthase
IEN91_RS08370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS08370	COG0300	oxidoreductase activity
IEN91_RS08370	COG3321	synthase
IEN91_RS08370	COG4221	oxidoreductase activity
IEN91_RS08375	COG0300	oxidoreductase activity
IEN91_RS08375	COG3321	synthase
IEN91_RS08375	COG4221	oxidoreductase activity
IEN91_RS08375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS08380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS08380	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS08380	COG3321	synthase
IEN91_RS08380	COG4221	oxidoreductase activity
IEN91_RS08385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IEN91_RS08390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IEN91_RS08395	COG0022	dehydrogenase e1 component
IEN91_RS08400	COG0508	dehydrogenase complex catalyzes the overall conversion of
IEN91_RS08405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEN91_RS08410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IEN91_RS08425	COG1982	Orn Lys Arg decarboxylase major
IEN91_RS08445	COG0483	inositol monophosphate 1-phosphatase activity
IEN91_RS08455	COG3227	Zinc metalloprotease (Elastase)
IEN91_RS08480	COG1217	gtp-binding protein TYPA
IEN91_RS08490	COG4896	Protein conserved in bacteria
IEN91_RS08500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IEN91_RS08505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IEN91_RS08510	COG2066	Belongs to the glutaminase family
IEN91_RS08520	COG0772	Belongs to the SEDS family
IEN91_RS08525	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IEN91_RS08540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IEN91_RS08540	COG2010	Cytochrome c
IEN91_RS08545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IEN91_RS08550	COG1845	cytochrome c oxidase, subunit III
IEN91_RS08555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IEN91_RS08560	COG3336	cytochrome c oxidase
IEN91_RS08570	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IEN91_RS08575	COG2340	Cysteine-rich secretory protein family
IEN91_RS08590	COG3679	Belongs to the UPF0342 family
IEN91_RS08605	COG0742	ribosomal rna small subunit methyltransferase
IEN91_RS08615	COG3314	Sporulation integral membrane protein YlbJ
IEN91_RS08620	COG1752	Esterase of the alpha-beta hydrolase superfamily
IEN91_RS08625	COG3480	Lon protease (S16) C-terminal proteolytic domain
IEN91_RS08635	COG1399	metal-binding, possibly nucleic acid-binding protein
IEN91_RS08655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IEN91_RS08675	COG4839	cell division protein FtsL
IEN91_RS08680	COG0768	penicillin binding
IEN91_RS08685	COG0768	penicillin binding
IEN91_RS08705	COG0772	Belongs to the SEDS family
IEN91_RS08720	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IEN91_RS08725	COG0849	cell division
IEN91_RS08730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IEN91_RS08735	COG1404	Belongs to the peptidase S8 family
IEN91_RS08735	COG4412	M6 family metalloprotease domain protein
IEN91_RS08745	COG1191	sigma factor activity
IEN91_RS08750	COG1191	sigma factor activity
IEN91_RS08755	COG1119	ATPase activity
IEN91_RS08760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IEN91_RS08765	COG1873	PFAM PRC-barrel domain
IEN91_RS08770	COG1496	oxidoreductase activity
IEN91_RS08775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IEN91_RS08785	COG0762	integral membrane protein
IEN91_RS08790	COG2302	S4 RNA-binding domain
IEN91_RS08795	COG3599	regulation of cell shape
IEN91_RS08800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IEN91_RS08805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IEN91_RS08815	COG0564	pseudouridine synthase activity
IEN91_RS08825	COG2233	PERMEase
IEN91_RS08835	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IEN91_RS08840	COG0505	Belongs to the CarA family
IEN91_RS08845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IEN91_RS08860	COG0284	orotidine-5'-phosphate decarboxylase activity
IEN91_RS08865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IEN91_RS08875	COG0306	phosphate transporter
IEN91_RS08890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IEN91_RS08895	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
IEN91_RS08900	COG1648	precorrin-2 dehydrogenase activity
IEN91_RS08910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IEN91_RS08915	COG1561	YicC-like family, N-terminal region
IEN91_RS08925	COG0194	GDP metabolic process
IEN91_RS08935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IEN91_RS08940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEN91_RS08945	COG0242	peptide deformylase activity
IEN91_RS08955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IEN91_RS08955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IEN91_RS08965	COG0631	protein serine/threonine phosphatase activity
IEN91_RS08970	COG2815	serine threonine protein kinase
IEN91_RS08970	COG0515	serine threonine protein kinase
IEN91_RS08980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IEN91_RS08985	COG1564	THIamine pyrophosphokinase
IEN91_RS09000	COG1302	Protein conserved in bacteria
IEN91_RS09005	COG1461	Dihydroxyacetone kinase
IEN91_RS09010	COG1760	l-serine dehydratase
IEN91_RS09015	COG1760	l-serine dehydratase
IEN91_RS09020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IEN91_RS09035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IEN91_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS09055	COG1196	nuclear chromosome segregation
IEN91_RS09060	COG0552	protein localization to endoplasmic reticulum
IEN91_RS09075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IEN91_RS09085	COG1837	Belongs to the UPF0109 family
IEN91_RS09110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IEN91_RS09125	COG2257	FlhB HrpN YscU SpaS Family
IEN91_RS09135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IEN91_RS09140	COG0758	DNA mediated transformation
IEN91_RS09145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEN91_RS09155	COG4974	Belongs to the 'phage' integrase family
IEN91_RS09175	COG1815	bacterial-type flagellum-dependent cell motility
IEN91_RS09180	COG1558	bacterial-type flagellum-dependent cell motility
IEN91_RS09185	COG1677	Flagellar hook-basal body complex protein FliE
IEN91_RS09190	COG1766	The M ring may be actively involved in energy transduction
IEN91_RS09195	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IEN91_RS09200	COG1317	bacterial-type flagellum organization
IEN91_RS09205	COG1157	protein secretion by the type III secretion system
IEN91_RS09210	COG2882	bacterial-type flagellum organization
IEN91_RS09215	COG3334	PFAM MgtE intracellular
IEN91_RS09220	COG3144	bacterial-type flagellum assembly
IEN91_RS09225	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IEN91_RS09230	COG4786	Flagellar basal body rod
IEN91_RS09235	COG1582	Flagellar protein (FlbD)
IEN91_RS09240	COG1580	Controls the rotational direction of flagella during chemotaxis
IEN91_RS09245	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IEN91_RS09250	COG1776	CheC inhibitor of MCP methylation
IEN91_RS09250	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IEN91_RS09255	COG2201	protein-glutamate methylesterase activity
IEN91_RS09260	COG3190	flagellar
IEN91_RS09265	COG1338	Plays a role in the flagellum-specific transport system
IEN91_RS09270	COG1987	bacterial-type flagellum assembly
IEN91_RS09275	COG1684	flagellar biosynthetic protein fliR
IEN91_RS09280	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IEN91_RS09285	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IEN91_RS09290	COG1419	protein localization to endoplasmic reticulum
IEN91_RS09295	COG0455	bacterial-type flagellum organization
IEN91_RS09300	COG2201	protein-glutamate methylesterase activity
IEN91_RS09305	COG0643	Histidine kinase
IEN91_RS09305	COG2198	Histidine kinase
IEN91_RS09310	COG0835	chemotaxis
IEN91_RS09315	COG1776	CheC inhibitor of MCP methylation
IEN91_RS09325	COG1191	sigma factor activity
IEN91_RS09355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEN91_RS09360	COG4589	Belongs to the CDS family
IEN91_RS09370	COG0750	zinc metalloprotease
IEN91_RS09380	COG2176	DNA-directed DNA polymerase activity
IEN91_RS09390	COG0195	Participates in both transcription termination and antitermination
IEN91_RS09395	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IEN91_RS09400	COG1358	cellular component organization or biogenesis
IEN91_RS09410	COG1550	Protein conserved in bacteria
IEN91_RS09425	COG0196	riboflavin kinase activity
IEN91_RS09440	COG0726	polysaccharide deacetylase
IEN91_RS09445	COG0612	Peptidase, M16
IEN91_RS09450	COG1873	PFAM PRC-barrel domain
IEN91_RS09455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEN91_RS09460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IEN91_RS09465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IEN91_RS09470	COG0527	aspartate kinase activity
IEN91_RS09480	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEN91_RS09485	COG0740	serine-type endopeptidase activity
IEN91_RS09495	COG1674	ftsk spoiiie
IEN91_RS09495	COG4980	gas vesicle protein
IEN91_RS09500	COG2188	Transcriptional regulator
IEN91_RS09505	COG2814	Major facilitator Superfamily
IEN91_RS09510	COG1846	Transcriptional regulator
IEN91_RS09515	COG2409	Drug exporters of the RND superfamily
IEN91_RS09515	COG1033	growth of symbiont in host cell
IEN91_RS09520	COG0612	Peptidase, M16
IEN91_RS09525	COG0612	Peptidase, M16
IEN91_RS09530	COG0300	oxidoreductase activity
IEN91_RS09545	COG1426	Protein conserved in bacteria
IEN91_RS09550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEN91_RS09565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IEN91_RS09575	COG1692	metallophosphoesterase
IEN91_RS09580	COG2359	stage V sporulation protein S
IEN91_RS09600	COG4550	Control of competence regulator ComK, YlbF/YmcA
IEN91_RS09645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS09650	COG3425	synthase
IEN91_RS09655	COG1024	Enoyl-CoA hydratase
IEN91_RS09660	COG1024	Enoyl-CoA hydratase
IEN91_RS09665	COG0300	oxidoreductase activity
IEN91_RS09665	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS09665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS09665	COG3321	synthase
IEN91_RS09665	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS09670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS09670	COG4221	oxidoreductase activity
IEN91_RS09670	COG0300	oxidoreductase activity
IEN91_RS09670	COG3321	synthase
IEN91_RS09675	COG3321	synthase
IEN91_RS09675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS09675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS09675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS09675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IEN91_RS09675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IEN91_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS09675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS09675	COG3321	synthase
IEN91_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS09680	COG3321	synthase
IEN91_RS09680	COG4221	oxidoreductase activity
IEN91_RS09680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS09685	COG3321	synthase
IEN91_RS09685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IEN91_RS09685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS09685	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IEN91_RS09690	COG2124	cytochrome p450
IEN91_RS09695	COG3209	COG3209 Rhs family protein
IEN91_RS09700	COG3619	membrane
IEN91_RS09710	COG1404	Belongs to the peptidase S8 family
IEN91_RS09720	COG4195	phage-related replication protein
IEN91_RS09725	COG1764	response to oxidative stress
IEN91_RS09730	COG2076	Multidrug Resistance protein
IEN91_RS09735	COG2076	Multidrug Resistance protein
IEN91_RS09775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEN91_RS09780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEN91_RS09785	COG4112	unkown
IEN91_RS09790	COG0860	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS09795	COG0464	growth
IEN91_RS09800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IEN91_RS09805	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IEN91_RS09810	COG0789	Transcriptional regulator
IEN91_RS09815	COG0174	glutamine synthetase
IEN91_RS09825	COG2211	Major facilitator Superfamily
IEN91_RS09830	COG3507	Belongs to the glycosyl hydrolase 43 family
IEN91_RS09845	COG1070	Carbohydrate kinase
IEN91_RS09850	COG3848	Pyruvate phosphate dikinase
IEN91_RS09850	COG0574	Belongs to the PEP-utilizing enzyme family
IEN91_RS09870	COG1064	alcohol dehydrogenase
IEN91_RS09900	COG3397	chitin binding
IEN91_RS09910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IEN91_RS09925	COG5434	Belongs to the glycosyl hydrolase 28 family
IEN91_RS09930	COG0756	dUTP diphosphatase activity
IEN91_RS09935	COG4195	phage-related replication protein
IEN91_RS09970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IEN91_RS09980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IEN91_RS10000	COG0785	Cytochrome C biogenesis protein
IEN91_RS10005	COG2201	protein-glutamate methylesterase activity
IEN91_RS10010	COG4846	Membrane protein involved in cytochrome C biogenesis
IEN91_RS10020	COG0071	Belongs to the small heat shock protein (HSP20) family
IEN91_RS10035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IEN91_RS10040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IEN91_RS10060	COG0824	Thioesterase
IEN91_RS10070	COG4841	protein insertion into membrane
IEN91_RS10080	COG1832	CoA-binding protein
IEN91_RS10085	COG0187	DNA topoisomerase II activity
IEN91_RS10090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEN91_RS10100	COG1115	amino acid carrier protein
IEN91_RS10110	COG1063	alcohol dehydrogenase
IEN91_RS10115	COG0800	Aldolase
IEN91_RS10120	COG1312	Catalyzes the dehydration of D-mannonate
IEN91_RS10125	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS10130	COG1609	Transcriptional regulator
IEN91_RS10135	COG2271	Major facilitator Superfamily
IEN91_RS10170	COG2205	protein histidine kinase activity
IEN91_RS10175	COG0745	RESPONSE REGULATOR receiver
IEN91_RS10185	COG3507	Belongs to the glycosyl hydrolase 43 family
IEN91_RS10210	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS10215	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEN91_RS10220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEN91_RS10225	COG2610	gluconate transmembrane transporter activity
IEN91_RS10230	COG2124	cytochrome p450
IEN91_RS10250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IEN91_RS10260	COG2246	polysaccharide biosynthetic process
IEN91_RS10265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IEN91_RS10270	COG0586	Pfam SNARE associated Golgi protein
IEN91_RS10275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IEN91_RS10280	COG1024	Enoyl-CoA hydratase
IEN91_RS10285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IEN91_RS10290	COG0511	ligase activity, forming carbon-carbon bonds
IEN91_RS10295	COG0439	Biotin carboxylase
IEN91_RS10300	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS10305	COG1960	acyl-CoA dehydrogenase activity
IEN91_RS10310	COG1649	PFAM Uncharacterised BCR, COG1649
IEN91_RS10320	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IEN91_RS10320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS10325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS10330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS10335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS10340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS10345	COG2027	D-alanyl-D-alanine carboxypeptidase
IEN91_RS10350	COG2017	converts alpha-aldose to the beta-anomer
IEN91_RS10355	COG0534	Mate efflux family protein
IEN91_RS10370	COG0582	viral genome integration into host DNA
IEN91_RS10375	COG0166	Belongs to the GPI family
IEN91_RS10380	COG0405	Gamma-glutamyltransferase
IEN91_RS10385	COG2814	Major facilitator Superfamily
IEN91_RS10390	COG0640	Transcriptional regulator
IEN91_RS10405	COG0604	alcohol dehydrogenase
IEN91_RS10410	COG0493	'glutamate synthase
IEN91_RS10415	COG0069	glutamate synthase activity
IEN91_RS10415	COG0070	glutamate synthase
IEN91_RS10415	COG0067	glutamate synthase
IEN91_RS10420	COG0583	DNA-binding transcription factor activity
IEN91_RS10425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IEN91_RS10440	COG0300	oxidoreductase activity
IEN91_RS10445	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IEN91_RS10455	COG2814	Major facilitator Superfamily
IEN91_RS10460	COG1070	Carbohydrate kinase
IEN91_RS10465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IEN91_RS10470	COG0243	molybdopterin cofactor binding
IEN91_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS10495	COG1733	regulation of RNA biosynthetic process
IEN91_RS10500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEN91_RS10510	COG1309	transcriptional regulator
IEN91_RS10515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEN91_RS10525	COG0640	Transcriptional regulator
IEN91_RS10530	COG0741	lytic transglycosylase activity
IEN91_RS10535	COG2322	membrane
IEN91_RS10550	COG1619	proteins homologs of microcin C7 resistance protein MccF
IEN91_RS10560	COG1388	LysM domain
IEN91_RS10560	COG3584	3D domain protein
IEN91_RS10565	COG0514	ATP-dependent DNA helicase (RecQ)
IEN91_RS10575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEN91_RS10580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IEN91_RS10595	COG0071	Belongs to the small heat shock protein (HSP20) family
IEN91_RS10625	COG1012	belongs to the aldehyde dehydrogenase family
IEN91_RS10630	COG1657	PFAM Prenyltransferase squalene oxidase
IEN91_RS10635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IEN91_RS10640	COG0733	neurotransmitter:sodium symporter activity
IEN91_RS10645	COG0385	Bile acid
IEN91_RS10650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEN91_RS10655	COG0508	dehydrogenase complex catalyzes the overall conversion of
IEN91_RS10665	COG4548	von Willebrand factor, type A
IEN91_RS10670	COG0714	Associated with various cellular activities
IEN91_RS10675	COG2032	superoxide dismutase activity
IEN91_RS10680	COG1388	LysM domain
IEN91_RS10680	COG0791	NLP P60 protein
IEN91_RS10685	COG1819	glycosyl
IEN91_RS10690	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IEN91_RS10695	COG0534	Mate efflux family protein
IEN91_RS10700	COG1366	Belongs to the anti-sigma-factor antagonist family
IEN91_RS10705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IEN91_RS10710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IEN91_RS10720	COG2962	Rard protein
IEN91_RS10735	COG1942	4-Oxalocrotonate Tautomerase
IEN91_RS10745	COG1733	regulation of RNA biosynthetic process
IEN91_RS10750	COG0778	Nitroreductase
IEN91_RS10755	COG0400	carboxylic ester hydrolase activity
IEN91_RS10760	COG0346	lactoylglutathione lyase activity
IEN91_RS10770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEN91_RS10780	COG2723	6-phospho-beta-galactosidase activity
IEN91_RS10785	COG2188	Transcriptional regulator
IEN91_RS10790	COG3409	Peptidoglycan-binding domain 1 protein
IEN91_RS10790	COG0793	Belongs to the peptidase S41A family
IEN91_RS10795	COG2226	methyltransferase
IEN91_RS10805	COG1876	peptidase activity
IEN91_RS10825	COG0671	phosphoesterase, PA-phosphatase related
IEN91_RS10860	COG1509	lysine 2,3-aminomutase activity
IEN91_RS10865	COG0456	acetyltransferase
IEN91_RS10870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IEN91_RS10875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEN91_RS10880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEN91_RS10885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IEN91_RS10890	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IEN91_RS10900	COG0456	acetyltransferase
IEN91_RS10905	COG0463	Glycosyl transferase, family 2
IEN91_RS10920	COG4641	Protein conserved in bacteria
IEN91_RS10930	COG1086	Polysaccharide biosynthesis protein
IEN91_RS10970	COG0457	Tetratricopeptide repeat
IEN91_RS10980	COG3391	amine dehydrogenase activity
IEN91_RS11020	COG5444	nuclease activity
IEN91_RS11025	COG4282	regulation of fungal-type cell wall biogenesis
IEN91_RS11030	COG1525	nuclease
IEN91_RS11045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IEN91_RS11065	COG1846	Transcriptional regulator
IEN91_RS11070	COG4698	Protein conserved in bacteria
IEN91_RS11075	COG2755	lipolytic protein G-D-S-L family
IEN91_RS11080	COG1999	signal sequence binding
IEN91_RS11090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IEN91_RS11095	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IEN91_RS11100	COG1272	protein, Hemolysin III
IEN91_RS11105	COG0204	Acyl-transferase
IEN91_RS11110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEN91_RS11125	COG2521	methyltransferase
IEN91_RS11125	COG2136	Putative SAM-dependent methyltransferase
IEN91_RS11140	COG1413	lyase activity
IEN91_RS11145	COG1418	mRNA catabolic process
IEN91_RS11150	COG0386	Belongs to the glutathione peroxidase family
IEN91_RS11160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IEN91_RS11170	COG1278	Cold shock
IEN91_RS11190	COG0328	RNA-DNA hybrid ribonuclease activity
IEN91_RS11195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IEN91_RS11200	COG0328	RNA-DNA hybrid ribonuclease activity
IEN91_RS11210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEN91_RS11225	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IEN91_RS11235	COG1755	Isoprenylcysteine carboxyl methyltransferase
IEN91_RS11240	COG3424	synthase
IEN91_RS11265	COG1335	isochorismatase
IEN91_RS11290	COG0438	transferase activity, transferring glycosyl groups
IEN91_RS11295	COG5632	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS11300	COG4824	toxin secretion phage lysis holin
IEN91_RS11320	COG5434	Belongs to the glycosyl hydrolase 28 family
IEN91_RS11325	COG1705	Flagellar rod assembly protein muramidase FlgJ
IEN91_RS11335	COG3953	SLT domain
IEN91_RS11335	COG5280	Phage tail tape measure protein TP901
IEN91_RS11440	COG1595	DNA-templated transcription, initiation
IEN91_RS11475	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IEN91_RS11480	COG1484	DNA-dependent DNA replication
IEN91_RS11485	COG3935	DnaD domain protein
IEN91_RS11520	COG3646	Phage regulatory protein
IEN91_RS11520	COG3645	SOS response
IEN91_RS11535	COG3620	sequence-specific DNA binding
IEN91_RS11540	COG0582	viral genome integration into host DNA
IEN91_RS11545	COG2233	PERMEase
IEN91_RS11555	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IEN91_RS11560	COG1199	ATP-dependent helicase activity
IEN91_RS11575	COG0116	Belongs to the methyltransferase superfamily
IEN91_RS11605	COG3359	exonuclease
IEN91_RS11610	COG1111	helicase
IEN91_RS11610	COG1205	dead DEAH box helicase
IEN91_RS11615	COG2190	(PTS) system
IEN91_RS11620	COG0071	Belongs to the small heat shock protein (HSP20) family
IEN91_RS11660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IEN91_RS11660	COG4499	WXG100 protein secretion system (Wss), protein YukC
IEN91_RS11670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEN91_RS11675	COG3935	DnaD domain protein
IEN91_RS11685	COG0436	Aminotransferase
IEN91_RS11690	COG5353	protein conserved in bacteria
IEN91_RS11700	COG1199	ATP-dependent helicase activity
IEN91_RS11700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IEN91_RS11730	COG0438	transferase activity, transferring glycosyl groups
IEN91_RS11735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IEN91_RS11750	COG1694	Mazg nucleotide pyrophosphohydrolase
IEN91_RS11755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEN91_RS11760	COG2140	Oxalate decarboxylase
IEN91_RS11770	COG4347	Protein of unknown function (DUF1405)
IEN91_RS11775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IEN91_RS11775	COG2010	Cytochrome c
IEN91_RS11780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IEN91_RS11785	COG0723	plastoquinol--plastocyanin reductase activity
IEN91_RS11800	COG0457	Tetratricopeptide repeat
IEN91_RS11810	COG0287	Prephenate dehydrogenase
IEN91_RS11845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IEN91_RS11850	COG4401	Chorismate mutase type I
IEN91_RS11865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IEN91_RS11870	COG0105	UTP biosynthetic process
IEN91_RS11875	COG0142	geranyltranstransferase activity
IEN91_RS11885	COG0142	geranyltranstransferase activity
IEN91_RS11900	COG0776	regulation of translation
IEN91_RS11905	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IEN91_RS11945	COG0539	negative regulation of cytoplasmic translation
IEN91_RS11960	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IEN91_RS11965	COG2959	enzyme of heme biosynthesis
IEN91_RS11970	COG3409	Peptidoglycan-binding domain 1 protein
IEN91_RS11970	COG3773	Cell wall hydrolase
IEN91_RS11975	COG2339	peptidase activity
IEN91_RS11980	COG0492	ferredoxin-NADP+ reductase activity
IEN91_RS11985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IEN91_RS11990	COG4862	establishment of competence for transformation
IEN91_RS11995	COG1408	metallophosphoesterase
IEN91_RS12005	COG1388	LysM domain
IEN91_RS12010	COG1266	CAAX protease self-immunity
IEN91_RS12015	COG0514	ATP-dependent DNA helicase (RecQ)
IEN91_RS12020	COG4955	Helix-turn-helix domain
IEN91_RS12025	COG1141	Ferredoxin
IEN91_RS12030	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IEN91_RS12035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IEN91_RS12045	COG1595	DNA-templated transcription, initiation
IEN91_RS12050	COG5002	protein histidine kinase activity
IEN91_RS12055	COG0745	RESPONSE REGULATOR receiver
IEN91_RS12060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IEN91_RS12065	COG1333	cytochrome c biogenesis protein
IEN91_RS12070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IEN91_RS12075	COG1187	pseudouridine synthase activity
IEN91_RS12080	COG0700	Nucleoside recognition
IEN91_RS12085	COG2715	membrane protein required for spore maturation
IEN91_RS12090	COG1686	Belongs to the peptidase S11 family
IEN91_RS12115	COG1547	Domain of unknown function (DUF309)
IEN91_RS12120	COG0456	acetyltransferase
IEN91_RS12135	COG0307	riboflavin synthase, alpha
IEN91_RS12140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEN91_RS12140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEN91_RS12150	COG0681	Belongs to the peptidase S26 family
IEN91_RS12160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IEN91_RS12165	COG4086	secreted protein
IEN91_RS12170	COG0019	diaminopimelate decarboxylase activity
IEN91_RS12175	COG0697	spore germination
IEN91_RS12190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEN91_RS12210	COG1191	sigma factor activity
IEN91_RS12220	COG1366	Belongs to the anti-sigma-factor antagonist family
IEN91_RS12225	COG1686	Belongs to the peptidase S11 family
IEN91_RS12230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IEN91_RS12235	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IEN91_RS12240	COG4974	Belongs to the 'phage' integrase family
IEN91_RS12250	COG0735	belongs to the Fur family
IEN91_RS12255	COG1300	Membrane
IEN91_RS12270	COG0281	malic enzyme
IEN91_RS12275	COG1757	Na H antiporter
IEN91_RS12280	COG1027	Aspartate ammonia-lyase
IEN91_RS12285	COG0252	asparaginase activity
IEN91_RS12290	COG1396	sequence-specific DNA binding
IEN91_RS12295	COG1379	DNA repair
IEN91_RS12300	COG0494	nUDIX hydrolase
IEN91_RS12310	COG0667	Aldo Keto reductase
IEN91_RS12320	COG1073	alpha beta
IEN91_RS12330	COG4918	Iron-sulphur cluster biosynthesis
IEN91_RS12335	COG0456	acetyltransferase
IEN91_RS12335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IEN91_RS12340	COG2329	Antibiotic biosynthesis monooxygenase
IEN91_RS12345	COG0456	acetyltransferase
IEN91_RS12350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEN91_RS12365	COG0628	permease
IEN91_RS12385	COG3048	D-serine ammonia-lyase activity
IEN91_RS12390	COG0300	oxidoreductase activity
IEN91_RS12395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEN91_RS12400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEN91_RS12405	COG1024	Enoyl-CoA hydratase
IEN91_RS12410	COG3425	synthase
IEN91_RS12415	COG2124	cytochrome p450
IEN91_RS12420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS12420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IEN91_RS12420	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS12420	COG3321	synthase
IEN91_RS12420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS12425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS12425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IEN91_RS12425	COG3321	synthase
IEN91_RS12425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS12430	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS12430	COG3321	synthase
IEN91_RS12430	COG0300	oxidoreductase activity
IEN91_RS12430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS12435	COG3321	synthase
IEN91_RS12435	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS12435	COG0300	oxidoreductase activity
IEN91_RS12435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS12435	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS12440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS12440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IEN91_RS12440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS12440	COG3321	synthase
IEN91_RS12440	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS12445	COG0300	oxidoreductase activity
IEN91_RS12445	COG3321	synthase
IEN91_RS12445	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS12445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS12445	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS12450	COG3321	synthase
IEN91_RS12450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEN91_RS12450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS12450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IEN91_RS12455	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS12460	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS12475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IEN91_RS12475	COG2070	2-Nitropropane dioxygenase
IEN91_RS12500	COG0596	Alpha beta hydrolase
IEN91_RS12515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IEN91_RS12520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IEN91_RS12535	COG0706	membrane insertase activity
IEN91_RS12540	COG2195	Cleaves the N-terminal amino acid of tripeptides
IEN91_RS12545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IEN91_RS12550	COG0346	lactoylglutathione lyase activity
IEN91_RS12560	COG1376	ErfK ybiS ycfS ynhG family protein
IEN91_RS12565	COG4129	membrane
IEN91_RS12570	COG1126	abc transporter atp-binding protein
IEN91_RS12575	COG0765	amino acid transport
IEN91_RS12580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEN91_RS12590	COG1597	lipid kinase activity
IEN91_RS12595	COG0508	dehydrogenase complex catalyzes the overall conversion of
IEN91_RS12600	COG0022	dehydrogenase e1 component
IEN91_RS12605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IEN91_RS12610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEN91_RS12615	COG3426	butyrate kinase activity
IEN91_RS12620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IEN91_RS12625	COG0280	phosphate acetyltransferase
IEN91_RS12630	COG3829	transcription factor binding
IEN91_RS12630	COG3290	protein histidine kinase activity
IEN91_RS12640	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IEN91_RS12645	COG2079	MmgE PrpD family protein
IEN91_RS12650	COG0372	Belongs to the citrate synthase family
IEN91_RS12655	COG1960	acyl-CoA dehydrogenase activity
IEN91_RS12660	COG1250	3-hydroxyacyl-CoA dehydrogenase
IEN91_RS12665	COG0183	Belongs to the thiolase family
IEN91_RS12670	COG0584	glycerophosphoryl diester phosphodiesterase
IEN91_RS12675	COG0860	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS12700	COG1902	pentaerythritol trinitrate reductase activity
IEN91_RS12715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEN91_RS12720	COG0745	RESPONSE REGULATOR receiver
IEN91_RS12725	COG0750	zinc metalloprotease
IEN91_RS12730	COG0497	DNA recombination
IEN91_RS12740	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IEN91_RS12750	COG0142	geranyltranstransferase activity
IEN91_RS12760	COG1570	exodeoxyribonuclease VII activity
IEN91_RS12775	COG1302	Protein conserved in bacteria
IEN91_RS12780	COG0439	Biotin carboxylase
IEN91_RS12785	COG0511	ligase activity, forming carbon-carbon bonds
IEN91_RS12825	COG3854	ATPases associated with a variety of cellular activities
IEN91_RS12840	COG0006	proline dipeptidase activity
IEN91_RS12850	COG3872	metal-dependent enzyme
IEN91_RS12860	COG1752	Esterase of the alpha-beta hydrolase superfamily
IEN91_RS12875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IEN91_RS12895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IEN91_RS12910	COG1396	sequence-specific DNA binding
IEN91_RS12920	COG0681	Belongs to the peptidase S26 family
IEN91_RS12945	COG4940	Competence protein ComGF
IEN91_RS12955	COG4970	Tfp pilus assembly protein FimT
IEN91_RS12960	COG4537	Required for transformation and DNA binding
IEN91_RS12965	COG1459	type II secretion system
IEN91_RS12970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IEN91_RS12975	COG0598	Magnesium transport protein CorA
IEN91_RS12980	COG1253	flavin adenine dinucleotide binding
IEN91_RS12985	COG1366	Belongs to the anti-sigma-factor antagonist family
IEN91_RS12995	COG1393	Belongs to the ArsC family
IEN91_RS13005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEN91_RS13015	COG0011	TIGRFAM Protein of
IEN91_RS13025	COG2866	Carboxypeptidase
IEN91_RS13030	COG1940	carbohydrate kinase activity
IEN91_RS13035	COG4483	Protein conserved in bacteria
IEN91_RS13040	COG1757	Na H antiporter
IEN91_RS13050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IEN91_RS13065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEN91_RS13070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IEN91_RS13075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IEN91_RS13080	COG0581	inorganic phosphate transmembrane transporter activity
IEN91_RS13085	COG0573	inorganic phosphate transmembrane transporter activity
IEN91_RS13090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IEN91_RS13095	COG0768	penicillin binding
IEN91_RS13100	COG0477	Major facilitator Superfamily
IEN91_RS13105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IEN91_RS13110	COG2839	Protein conserved in bacteria
IEN91_RS13115	COG5521	maltodextrose utilization protein MalA
IEN91_RS13120	COG1388	LysM domain
IEN91_RS13130	COG4709	membrane
IEN91_RS13135	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
IEN91_RS13140	COG0735	belongs to the Fur family
IEN91_RS13145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEN91_RS13160	COG0513	Belongs to the DEAD box helicase family
IEN91_RS13175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEN91_RS13180	COG2384	SAM-dependent methyltransferase
IEN91_RS13185	COG2010	Cytochrome c
IEN91_RS13190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEN91_RS13195	COG0358	DNA primase activity
IEN91_RS13210	COG0517	IMP dehydrogenase activity
IEN91_RS13215	COG0751	glycine-tRNA ligase activity
IEN91_RS13235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEN91_RS13240	COG0295	cytidine deaminase activity
IEN91_RS13245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IEN91_RS13255	COG1480	7TM receptor with intracellular HD hydrolase
IEN91_RS13260	COG1702	phosphate starvation-inducible protein PhoH
IEN91_RS13265	COG0561	phosphatase activity
IEN91_RS13280	COG4864	UPF0365 protein
IEN91_RS13285	COG1030	water channel activity
IEN91_RS13290	COG1610	YqeY-like protein
IEN91_RS13300	COG1283	sodium-dependent phosphate transmembrane transporter activity
IEN91_RS13305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IEN91_RS13310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IEN91_RS13340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IEN91_RS13355	COG0860	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS13370	COG1466	dna polymerase III delta subunit
IEN91_RS13385	COG2333	competence protein COMEC
IEN91_RS13385	COG0658	competence protein
IEN91_RS13390	COG2131	deaminase
IEN91_RS13395	COG1596	polysaccharide export
IEN91_RS13395	COG1555	photosystem II stabilization
IEN91_RS13400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEN91_RS13405	COG2226	methyltransferase
IEN91_RS13410	COG0799	negative regulation of ribosome biogenesis
IEN91_RS13415	COG1713	HD superfamily hydrolase involved in NAD metabolism
IEN91_RS13425	COG1534	Rna-binding protein
IEN91_RS13430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IEN91_RS13435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IEN91_RS13440	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IEN91_RS13450	COG2755	lipolytic protein G-D-S-L family
IEN91_RS13460	COG0398	Pfam SNARE associated Golgi protein
IEN91_RS13485	COG2207	Transcriptional regulator
IEN91_RS13485	COG3708	Transcriptional regulator
IEN91_RS13490	COG0563	adenylate kinase activity
IEN91_RS13495	COG2814	Major facilitator Superfamily
IEN91_RS13505	COG0456	acetyltransferase
IEN91_RS13510	COG2318	DinB family
IEN91_RS13520	COG0561	phosphatase activity
IEN91_RS13525	COG0561	phosphatase activity
IEN91_RS13535	COG1482	cell wall glycoprotein biosynthetic process
IEN91_RS13540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEN91_RS13540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IEN91_RS13540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IEN91_RS13545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEN91_RS13545	COG3711	transcriptional antiterminator
IEN91_RS13555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IEN91_RS13560	COG0583	DNA-binding transcription factor activity
IEN91_RS13565	COG2814	Major facilitator Superfamily
IEN91_RS13570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IEN91_RS13570	COG2124	cytochrome p450
IEN91_RS13575	COG1309	transcriptional regulator
IEN91_RS13580	COG2226	methyltransferase
IEN91_RS13595	COG2116	formate transmembrane transporter activity
IEN91_RS13600	COG5609	conserved protein (DUF2294)
IEN91_RS13605	COG3383	formate dehydrogenase (NAD+) activity
IEN91_RS13610	COG2427	Protein of unknown function (DUF1641)
IEN91_RS13620	COG0626	cystathionine gamma-synthase activity
IEN91_RS13625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IEN91_RS13650	COG0768	penicillin binding
IEN91_RS13665	COG0826	peptidase U32
IEN91_RS13670	COG0826	peptidase U32
IEN91_RS13675	COG4122	O-methyltransferase activity
IEN91_RS13680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEN91_RS13695	COG4472	Bacterial protein of unknown function (DUF965)
IEN91_RS13705	COG0628	permease
IEN91_RS13710	COG1126	abc transporter atp-binding protein
IEN91_RS13715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEN91_RS13720	COG0765	amino acid transport
IEN91_RS13725	COG0765	amino acid transport
IEN91_RS13740	COG3881	PFAM PRC-barrel domain
IEN91_RS13745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IEN91_RS13750	COG0457	Tetratricopeptide repeat
IEN91_RS13760	COG1104	cysteine desulfurase activity
IEN91_RS13765	COG1959	2 iron, 2 sulfur cluster binding
IEN91_RS13770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IEN91_RS13775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IEN91_RS13800	COG0860	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS13800	COG4991	sh3 domain protein
IEN91_RS13800	COG3103	Sh3 type 3 domain protein
IEN91_RS13810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEN91_RS13820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IEN91_RS13820	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IEN91_RS13825	COG5416	Lipopolysaccharide assembly protein A domain
IEN91_RS13830	COG0490	domain, Protein
IEN91_RS13835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IEN91_RS13835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IEN91_RS13845	COG2244	polysaccharide biosynthetic process
IEN91_RS13850	COG2323	membrane
IEN91_RS13860	COG1862	Preprotein translocase
IEN91_RS13905	COG1388	LysM domain
IEN91_RS13915	COG0157	Belongs to the NadC ModD family
IEN91_RS13920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IEN91_RS13925	COG1104	cysteine desulfurase activity
IEN91_RS13930	COG1827	regulation of RNA biosynthetic process
IEN91_RS13935	COG0077	Prephenate dehydratase
IEN91_RS13950	COG3290	protein histidine kinase activity
IEN91_RS13955	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IEN91_RS13960	COG2868	ribosomal protein
IEN91_RS13970	COG1994	Peptidase M50
IEN91_RS13975	COG0739	heme binding
IEN91_RS13980	COG2894	cell division
IEN91_RS13990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IEN91_RS14000	COG1077	Cell shape determining protein MreB Mrl
IEN91_RS14020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IEN91_RS14025	COG0285	dihydrofolate synthase activity
IEN91_RS14030	COG0525	valine-tRNA ligase activity
IEN91_RS14040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IEN91_RS14045	COG1388	LysM domain
IEN91_RS14055	COG0113	porphobilinogen synthase activity
IEN91_RS14060	COG1587	Uroporphyrinogen-III synthase
IEN91_RS14070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IEN91_RS14090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IEN91_RS14095	COG1067	ATP-dependent peptidase activity
IEN91_RS14095	COG0470	DNA polymerase III
IEN91_RS14110	COG1477	protein flavinylation
IEN91_RS14110	COG0457	Tetratricopeptide repeat
IEN91_RS14125	COG0473	3-isopropylmalate dehydrogenase activity
IEN91_RS14140	COG0440	acetolactate synthase activity
IEN91_RS14145	COG0028	Belongs to the TPP enzyme family
IEN91_RS14170	COG0622	Phosphoesterase
IEN91_RS14175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IEN91_RS14185	COG5401	PFAM Sporulation and spore germination
IEN91_RS14195	COG1846	Transcriptional regulator
IEN91_RS14200	COG2197	response regulator
IEN91_RS14205	COG0824	Thioesterase
IEN91_RS14210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IEN91_RS14215	COG1053	succinate dehydrogenase
IEN91_RS14220	COG2009	succinate dehydrogenase
IEN91_RS14225	COG1719	4-vinyl reductase, 4VR
IEN91_RS14230	COG0527	aspartate kinase activity
IEN91_RS14240	COG3118	belongs to the thioredoxin family
IEN91_RS14245	COG3534	alpha-L-arabinofuranosidase
IEN91_RS14250	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IEN91_RS14255	COG2086	electron transfer activity
IEN91_RS14260	COG1024	Enoyl-CoA hydratase
IEN91_RS14265	COG1309	transcriptional regulator
IEN91_RS14270	COG0318	PFAM AMP-dependent synthetase and ligase
IEN91_RS14280	COG3766	membrane
IEN91_RS14290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IEN91_RS14290	COG1796	DNA polymerase
IEN91_RS14295	COG1286	toxin biosynthetic process
IEN91_RS14310	COG0072	phenylalanine-tRNA ligase activity
IEN91_RS14310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEN91_RS14315	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IEN91_RS14320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEN91_RS14330	COG3835	regulator
IEN91_RS14335	COG0277	FAD linked oxidase domain protein
IEN91_RS14340	COG0247	lactate metabolic process
IEN91_RS14345	COG1966	Carbon starvation protein
IEN91_RS14350	COG3534	alpha-L-arabinofuranosidase
IEN91_RS14355	COG0395	ABC-type sugar transport system, permease component
IEN91_RS14360	COG1175	transmembrane transport
IEN91_RS14365	COG1653	transport
IEN91_RS14375	COG0647	UMP catabolic process
IEN91_RS14380	COG0235	Class ii aldolase
IEN91_RS14385	COG1069	ribulokinase activity
IEN91_RS14390	COG2160	L-arabinose isomerase activity
IEN91_RS14395	COG3507	Belongs to the glycosyl hydrolase 43 family
IEN91_RS14400	COG1363	Peptidase, m42
IEN91_RS14410	COG3326	Membrane
IEN91_RS14415	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IEN91_RS14425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IEN91_RS14430	COG1346	cytolysis
IEN91_RS14435	COG1380	Effector of murein hydrolase LrgA
IEN91_RS14440	COG3279	Response regulator of the LytR AlgR family
IEN91_RS14445	COG3275	phosphorelay sensor kinase activity
IEN91_RS14450	COG1011	Hydrolase
IEN91_RS14465	COG0398	Pfam SNARE associated Golgi protein
IEN91_RS14470	COG1484	DNA-dependent DNA replication
IEN91_RS14475	COG3611	Membrane attachment protein
IEN91_RS14490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IEN91_RS14495	COG1733	regulation of RNA biosynthetic process
IEN91_RS14500	COG2814	Major facilitator Superfamily
IEN91_RS14505	COG0656	L-ascorbic acid biosynthetic process
IEN91_RS14510	COG0237	dephospho-CoA kinase activity
IEN91_RS14515	COG1971	Probably functions as a manganese efflux pump
IEN91_RS14520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IEN91_RS14525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEN91_RS14525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEN91_RS14530	COG5002	protein histidine kinase activity
IEN91_RS14535	COG0745	RESPONSE REGULATOR receiver
IEN91_RS14545	COG0538	isocitrate dehydrogenase activity
IEN91_RS14550	COG0372	Belongs to the citrate synthase family
IEN91_RS14575	COG0628	permease
IEN91_RS14580	COG3030	protein affecting phage T7 exclusion by the F plasmid
IEN91_RS14585	COG0469	pyruvate kinase activity
IEN91_RS14605	COG0281	malic enzyme
IEN91_RS14610	COG0587	DNA-directed DNA polymerase activity
IEN91_RS14630	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IEN91_RS14640	COG4109	DRTGG domain
IEN91_RS14650	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS14665	COG0521	Mo-molybdopterin cofactor biosynthetic process
IEN91_RS14675	COG0827	DNA restriction-modification system
IEN91_RS14680	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IEN91_RS14685	COG3874	Sporulation protein YtfJ
IEN91_RS14695	COG1714	RDD family
IEN91_RS14700	COG0616	signal peptide processing
IEN91_RS14705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEN91_RS14710	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IEN91_RS14715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IEN91_RS14730	COG1104	cysteine desulfurase activity
IEN91_RS14735	COG1114	Component of the transport system for branched-chain amino acids
IEN91_RS14745	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IEN91_RS14750	COG1309	transcriptional regulator
IEN91_RS14755	COG1956	GAF domain-containing protein
IEN91_RS14760	COG2203	Gaf domain
IEN91_RS14760	COG2199	diguanylate cyclase activity
IEN91_RS14770	COG1012	belongs to the aldehyde dehydrogenase family
IEN91_RS14795	COG1017	nitric oxide dioxygenase activity
IEN91_RS14795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEN91_RS14805	COG0693	protein deglycase activity
IEN91_RS14820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEN91_RS14825	COG1378	Sugar-specific transcriptional regulator TrmB
IEN91_RS14845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IEN91_RS14850	COG0454	-acetyltransferase
IEN91_RS14855	COG0517	IMP dehydrogenase activity
IEN91_RS14860	COG0123	including yeast histone deacetylase and acetoin utilization protein
IEN91_RS14865	COG1360	Flagellar Motor Protein
IEN91_RS14870	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IEN91_RS14875	COG1609	Transcriptional regulator
IEN91_RS14880	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IEN91_RS14880	COG1605	Chorismate mutase
IEN91_RS14885	COG3118	belongs to the thioredoxin family
IEN91_RS14890	COG4980	gas vesicle protein
IEN91_RS14895	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IEN91_RS14905	COG1674	ftsk spoiiie
IEN91_RS14910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEN91_RS14920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IEN91_RS14930	COG1363	Peptidase, m42
IEN91_RS14935	COG5584	Small secreted protein
IEN91_RS14940	COG0281	malic enzyme
IEN91_RS14945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEN91_RS14960	COG0510	thiamine kinase activity
IEN91_RS14965	COG1597	lipid kinase activity
IEN91_RS14975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IEN91_RS14980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IEN91_RS14985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IEN91_RS14990	COG2252	PERMEase
IEN91_RS14995	COG4473	ABC transporter
IEN91_RS15000	COG1131	(ABC) transporter
IEN91_RS15005	COG1349	DNA-binding transcription factor activity
IEN91_RS15010	COG1187	pseudouridine synthase activity
IEN91_RS15015	COG2244	polysaccharide biosynthetic process
IEN91_RS15020	COG2081	HI0933 family
IEN91_RS15025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IEN91_RS15035	COG1609	Transcriptional regulator
IEN91_RS15040	COG1653	transport
IEN91_RS15045	COG1175	transmembrane transport
IEN91_RS15050	COG0395	ABC-type sugar transport system, permease component
IEN91_RS15055	COG1486	melibiose metabolic process
IEN91_RS15065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IEN91_RS15080	COG2202	Pas domain
IEN91_RS15080	COG1366	Belongs to the anti-sigma-factor antagonist family
IEN91_RS15085	COG2814	Major facilitator Superfamily
IEN91_RS15090	COG5522	Integral membrane protein (intg_mem_TP0381)
IEN91_RS15095	COG0577	efflux transmembrane transporter activity
IEN91_RS15100	COG1136	(ABC) transporter
IEN91_RS15105	COG2205	protein histidine kinase activity
IEN91_RS15110	COG0745	RESPONSE REGULATOR receiver
IEN91_RS15115	COG0577	efflux transmembrane transporter activity
IEN91_RS15120	COG1136	(ABC) transporter
IEN91_RS15140	COG1131	(ABC) transporter
IEN91_RS15145	COG1725	Transcriptional regulator
IEN91_RS15155	COG0640	Transcriptional regulator
IEN91_RS15160	COG0477	Major facilitator Superfamily
IEN91_RS15165	COG1242	4 iron, 4 sulfur cluster binding
IEN91_RS15170	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IEN91_RS15180	COG0584	glycerophosphoryl diester phosphodiesterase
IEN91_RS15190	COG2267	carboxylic ester hydrolase activity
IEN91_RS15195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IEN91_RS15200	COG1113	amino acid transport
IEN91_RS15205	COG0367	asparagine synthase
IEN91_RS15225	COG1506	peptidase
IEN91_RS15230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEN91_RS15235	COG1116	anion transmembrane transporter activity
IEN91_RS15240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IEN91_RS15245	COG0494	nUDIX hydrolase
IEN91_RS15250	COG4824	toxin secretion phage lysis holin
IEN91_RS15255	COG0783	Belongs to the Dps family
IEN91_RS15280	COG0288	reversible hydration of carbon dioxide
IEN91_RS15290	COG1271	oxidase subunit
IEN91_RS15295	COG1294	oxidase, subunit
IEN91_RS15305	COG4948	Mandelate Racemase Muconate Lactonizing
IEN91_RS15315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IEN91_RS15320	COG0596	Alpha beta hydrolase
IEN91_RS15330	COG1169	isochorismate synthase
IEN91_RS15335	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IEN91_RS15340	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IEN91_RS15465	COG3859	Proton-coupled thiamine transporter YuaJ
IEN91_RS15470	COG2268	Band 7 protein
IEN91_RS15475	COG1585	Membrane protein implicated in regulation of membrane protease activity
IEN91_RS15480	COG2318	DinB family
IEN91_RS15490	COG1454	alcohol dehydrogenase
IEN91_RS15495	COG1012	belongs to the aldehyde dehydrogenase family
IEN91_RS15500	COG1510	regulation of RNA biosynthetic process
IEN91_RS15510	COG0569	domain protein
IEN91_RS15515	COG1705	Flagellar rod assembly protein muramidase FlgJ
IEN91_RS15520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEN91_RS15520	COG1017	nitric oxide dioxygenase activity
IEN91_RS15535	COG0457	Tetratricopeptide repeat
IEN91_RS15560	COG0628	permease
IEN91_RS15565	COG0673	inositol 2-dehydrogenase activity
IEN91_RS15570	COG0693	protein deglycase activity
IEN91_RS15575	COG0840	transmembrane signaling receptor activity
IEN91_RS15580	COG0840	transmembrane signaling receptor activity
IEN91_RS15585	COG0840	transmembrane signaling receptor activity
IEN91_RS15590	COG0840	transmembrane signaling receptor activity
IEN91_RS15605	COG2070	2-Nitropropane dioxygenase
IEN91_RS15610	COG0432	Pfam Uncharacterised protein family UPF0047
IEN91_RS15615	COG0366	Alpha amylase catalytic
IEN91_RS15620	COG1253	flavin adenine dinucleotide binding
IEN91_RS15625	COG2738	Putative neutral zinc metallopeptidase
IEN91_RS15640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IEN91_RS15665	COG1335	isochorismatase
IEN91_RS15670	COG1979	alcohol dehydrogenase
IEN91_RS15675	COG1979	alcohol dehydrogenase
IEN91_RS15680	COG2155	Conserved Protein
IEN91_RS15685	COG1098	S1 RNA binding domain
IEN91_RS15690	COG0436	Aminotransferase
IEN91_RS15695	COG1522	sequence-specific DNA binding
IEN91_RS15700	COG2267	carboxylic ester hydrolase activity
IEN91_RS15710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IEN91_RS15715	COG2205	protein histidine kinase activity
IEN91_RS15725	COG5018	Exonuclease
IEN91_RS15730	COG2814	Major facilitator Superfamily
IEN91_RS15735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IEN91_RS15740	COG3011	Protein conserved in bacteria
IEN91_RS15750	COG3290	protein histidine kinase activity
IEN91_RS15755	COG4565	transcriptional regulatory protein
IEN91_RS15760	COG1744	ABC transporter substrate-binding protein PnrA-like
IEN91_RS15765	COG3845	ABC transporter
IEN91_RS15770	COG4603	Belongs to the binding-protein-dependent transport system permease family
IEN91_RS15775	COG1079	Belongs to the binding-protein-dependent transport system permease family
IEN91_RS15785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IEN91_RS15785	COG2111	Na H antiporter
IEN91_RS15790	COG2111	Na H antiporter
IEN91_RS15795	COG1006	Multisubunit Na H antiporter MnhC subunit
IEN91_RS15800	COG0651	ATP synthesis coupled electron transport
IEN91_RS15805	COG1863	multisubunit Na H antiporter MnhE subunit
IEN91_RS15810	COG2212	antiporter activity
IEN91_RS15815	COG1320	monovalent cation:proton antiporter activity
IEN91_RS15820	COG2050	protein possibly involved in aromatic compounds catabolism
IEN91_RS15825	COG2197	response regulator
IEN91_RS15830	COG4585	Histidine kinase
IEN91_RS15840	COG0142	geranyltranstransferase activity
IEN91_RS15855	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IEN91_RS15860	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IEN91_RS15865	COG1335	isochorismatase
IEN91_RS15870	COG5506	Protein of unknown function (DUF1694)
IEN91_RS15885	COG0628	permease
IEN91_RS15895	COG1418	mRNA catabolic process
IEN91_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS15910	COG1511	domain protein
IEN91_RS15915	COG0433	COG0433 Predicted ATPase
IEN91_RS15915	COG1674	ftsk spoiiie
IEN91_RS15925	COG5417	Belongs to the EsaB family
IEN91_RS15930	COG4842	Belongs to the WXG100 family
IEN91_RS15935	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IEN91_RS15935	COG2508	Transcriptional regulator
IEN91_RS15940	COG0686	Belongs to the AlaDH PNT family
IEN91_RS15945	COG5634	Uncharacterized conserved protein (DUF2278)
IEN91_RS15950	COG3251	PFAM MbtH domain protein
IEN91_RS15955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEN91_RS15960	COG1535	isochorismatase
IEN91_RS15960	COG3433	isochorismatase activity
IEN91_RS15965	COG1021	2,3-dihydroxybenzoate-AMP ligase
IEN91_RS15970	COG1169	isochorismate synthase
IEN91_RS15975	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS15980	COG2819	hydrolase of the alpha beta superfamily
IEN91_RS15985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IEN91_RS15990	COG1268	BioY protein
IEN91_RS15995	COG2056	Na+-H+ antiporter family
IEN91_RS16005	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
IEN91_RS16010	COG3584	3D domain protein
IEN91_RS16025	COG1252	NADH dehydrogenase
IEN91_RS16055	COG1131	(ABC) transporter
IEN91_RS16080	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
IEN91_RS16085	COG0316	Belongs to the HesB IscA family
IEN91_RS16095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IEN91_RS16105	COG1252	NADH dehydrogenase
IEN91_RS16110	COG4837	Protein of unknown function (DUF1462)
IEN91_RS16115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IEN91_RS16120	COG0823	Involved in the tonB-independent uptake of proteins
IEN91_RS16120	COG4946	Tricorn protease homolog
IEN91_RS16120	COG1506	peptidase
IEN91_RS16130	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IEN91_RS16135	COG0460	homoserine dehydrogenase
IEN91_RS16140	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IEN91_RS16145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IEN91_RS16150	COG0647	UMP catabolic process
IEN91_RS16155	COG2445	Protein of unknown function DUF86
IEN91_RS16160	COG4470	Protein conserved in bacteria
IEN91_RS16170	COG0739	heme binding
IEN91_RS16180	COG0737	Belongs to the 5'-nucleotidase family
IEN91_RS16185	COG0730	response to heat
IEN91_RS16190	COG1801	Protein of unknown function DUF72
IEN91_RS16205	COG2508	Transcriptional regulator
IEN91_RS16230	COG2814	Major facilitator Superfamily
IEN91_RS16235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IEN91_RS16240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IEN91_RS16245	COG2356	endonuclease I
IEN91_RS16250	COG3842	ATPase activity
IEN91_RS16255	COG2188	Transcriptional regulator
IEN91_RS16260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEN91_RS16265	COG0395	ABC-type sugar transport system, permease component
IEN91_RS16270	COG1175	transmembrane transport
IEN91_RS16275	COG1653	transport
IEN91_RS16280	COG2222	sugar isomerase
IEN91_RS16285	COG0789	Transcriptional regulator
IEN91_RS16300	COG0322	excinuclease ABC activity
IEN91_RS16305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IEN91_RS16315	COG3409	Peptidoglycan-binding domain 1 protein
IEN91_RS16320	COG0719	Fe-S assembly protein
IEN91_RS16325	COG0822	iron-sulfur transferase activity
IEN91_RS16330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEN91_RS16335	COG0719	Fe-S assembly protein
IEN91_RS16340	COG0396	ATPase activity
IEN91_RS16350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEN91_RS16355	COG1464	Belongs to the NlpA lipoprotein family
IEN91_RS16360	COG2011	ABC-type metal ion transport system permease component
IEN91_RS16365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEN91_RS16375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IEN91_RS16380	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IEN91_RS16395	COG1393	Belongs to the ArsC family
IEN91_RS16400	COG1960	acyl-CoA dehydrogenase activity
IEN91_RS16405	COG0183	Belongs to the thiolase family
IEN91_RS16410	COG1024	Enoyl-CoA hydratase
IEN91_RS16410	COG1250	3-hydroxyacyl-CoA dehydrogenase
IEN91_RS16425	COG0477	Major facilitator Superfamily
IEN91_RS16435	COG5577	PFAM Coat F domain
IEN91_RS16440	COG1846	Transcriptional regulator
IEN91_RS16445	COG0477	Major facilitator Superfamily
IEN91_RS16450	COG0583	DNA-binding transcription factor activity
IEN91_RS16470	COG1120	ATPase activity
IEN91_RS16485	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS16490	COG0783	Belongs to the Dps family
IEN91_RS16495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEN91_RS16500	COG0745	RESPONSE REGULATOR receiver
IEN91_RS16505	COG2205	protein histidine kinase activity
IEN91_RS16505	COG2770	Histidine kinase
IEN91_RS16515	COG1309	transcriptional regulator
IEN91_RS16520	COG0114	fumarate hydratase activity
IEN91_RS16530	COG0697	spore germination
IEN91_RS16535	COG0814	amino acid
IEN91_RS16545	COG2197	response regulator
IEN91_RS16550	COG4585	Histidine kinase
IEN91_RS16555	COG4758	membrane
IEN91_RS16560	COG3595	metallopeptidase activity
IEN91_RS16565	COG1842	Phage shock protein A
IEN91_RS16570	COG4758	membrane
IEN91_RS16575	COG2814	Major facilitator Superfamily
IEN91_RS16580	COG2096	Adenosyltransferase
IEN91_RS16585	COG1120	ATPase activity
IEN91_RS16590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEN91_RS16595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IEN91_RS16600	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS16605	COG3386	PFAM SMP-30 Gluconolaconase
IEN91_RS16610	COG2205	protein histidine kinase activity
IEN91_RS16615	COG0745	RESPONSE REGULATOR receiver
IEN91_RS16625	COG1191	sigma factor activity
IEN91_RS16635	COG2140	Oxalate decarboxylase
IEN91_RS16645	COG1120	ATPase activity
IEN91_RS16650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEN91_RS16655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEN91_RS16660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IEN91_RS16665	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IEN91_RS16670	COG0531	amino acid
IEN91_RS16680	COG1988	membrane-bound metal-dependent
IEN91_RS16685	COG1368	sulfuric ester hydrolase activity
IEN91_RS16690	COG1910	domain protein
IEN91_RS16695	COG0725	ABC transporter, periplasmic molybdate-binding protein
IEN91_RS16700	COG4149	molybdate abc transporter
IEN91_RS16705	COG2197	response regulator
IEN91_RS16710	COG3850	Histidine kinase
IEN91_RS16715	COG1131	(ABC) transporter
IEN91_RS16725	COG0842	Transport permease protein
IEN91_RS16730	COG0656	L-ascorbic acid biosynthetic process
IEN91_RS16750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IEN91_RS16755	COG3973	AAA domain
IEN91_RS16760	COG2860	membrane
IEN91_RS16770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IEN91_RS16775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IEN91_RS16780	COG2217	Heavy metal translocating P-type atpase
IEN91_RS16785	COG2217	Heavy metal translocating P-type atpase
IEN91_RS16790	COG2608	mercury ion transmembrane transporter activity
IEN91_RS16795	COG1937	Protein conserved in bacteria
IEN91_RS16800	COG0673	inositol 2-dehydrogenase activity
IEN91_RS16815	COG2814	Major facilitator Superfamily
IEN91_RS16830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEN91_RS16835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IEN91_RS16840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEN91_RS16845	COG1126	abc transporter atp-binding protein
IEN91_RS16850	COG0765	amino acid transport
IEN91_RS16855	COG0765	amino acid transport
IEN91_RS16860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEN91_RS16865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEN91_RS16870	COG0454	-acetyltransferase
IEN91_RS16875	COG0583	DNA-binding transcription factor activity
IEN91_RS16880	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS16885	COG2732	(Barnase) inhibitor
IEN91_RS16900	COG0557	exoribonuclease II activity
IEN91_RS16905	COG1647	Serine aminopeptidase, S33
IEN91_RS16910	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IEN91_RS16915	COG1476	TRANSCRIPTIONal
IEN91_RS16920	COG1396	sequence-specific DNA binding
IEN91_RS16925	COG1396	sequence-specific DNA binding
IEN91_RS16930	COG1733	regulation of RNA biosynthetic process
IEN91_RS16955	COG1131	(ABC) transporter
IEN91_RS16960	COG1174	glycine betaine transport
IEN91_RS16965	COG1732	Glycine betaine
IEN91_RS16970	COG1174	glycine betaine transport
IEN91_RS16975	COG1125	glycine betaine transport
IEN91_RS16975	COG0517	IMP dehydrogenase activity
IEN91_RS16980	COG1510	regulation of RNA biosynthetic process
IEN91_RS16985	COG1174	glycine betaine transport
IEN91_RS16990	COG1732	Glycine betaine
IEN91_RS16995	COG1174	glycine betaine transport
IEN91_RS17000	COG1125	glycine betaine transport
IEN91_RS17000	COG0517	IMP dehydrogenase activity
IEN91_RS17005	COG1510	regulation of RNA biosynthetic process
IEN91_RS17010	COG2095	MarC family integral membrane protein
IEN91_RS17015	COG3064	Membrane
IEN91_RS17020	COG4640	response to antibiotic
IEN91_RS17025	COG0456	acetyltransferase
IEN91_RS17040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IEN91_RS17055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IEN91_RS17060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IEN91_RS17065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IEN91_RS17075	COG2234	aminopeptidase activity
IEN91_RS17095	COG0126	phosphoglycerate kinase activity
IEN91_RS17100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IEN91_RS17105	COG2390	Transcriptional regulator
IEN91_RS17110	COG2814	Major facilitator Superfamily
IEN91_RS17115	COG1609	Transcriptional regulator
IEN91_RS17120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEN91_RS17130	COG0583	DNA-binding transcription factor activity
IEN91_RS17135	COG0697	spore germination
IEN91_RS17140	COG1113	amino acid transport
IEN91_RS17150	COG1609	Transcriptional regulator
IEN91_RS17160	COG0561	phosphatase activity
IEN91_RS17165	COG1737	Transcriptional regulator
IEN91_RS17170	COG1070	Carbohydrate kinase
IEN91_RS17195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEN91_RS17200	COG2186	Transcriptional regulator
IEN91_RS17205	COG1620	l-lactate permease
IEN91_RS17210	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IEN91_RS17220	COG5039	Polysaccharide pyruvyl transferase
IEN91_RS17225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IEN91_RS17230	COG0110	maltose O-acetyltransferase activity
IEN91_RS17235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IEN91_RS17240	COG2244	polysaccharide biosynthetic process
IEN91_RS17245	COG1216	Glycosyl transferase, family 2
IEN91_RS17250	COG5039	Polysaccharide pyruvyl transferase
IEN91_RS17255	COG1216	Glycosyl transferase, family 2
IEN91_RS17265	COG0438	transferase activity, transferring glycosyl groups
IEN91_RS17270	COG1215	transferase activity, transferring glycosyl groups
IEN91_RS17275	COG0438	transferase activity, transferring glycosyl groups
IEN91_RS17280	COG1086	Polysaccharide biosynthesis protein
IEN91_RS17285	COG0489	protein tyrosine kinase activity
IEN91_RS17290	COG3944	biosynthesis protein
IEN91_RS17295	COG1396	sequence-specific DNA binding
IEN91_RS17300	COG2272	Belongs to the type-B carboxylesterase lipase family
IEN91_RS17310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEN91_RS17315	COG2364	Membrane
IEN91_RS17320	COG0456	acetyltransferase
IEN91_RS17325	COG3479	Phenolic acid decarboxylase
IEN91_RS17385	COG2223	nitrite transmembrane transporter activity
IEN91_RS17390	COG1609	Transcriptional regulator
IEN91_RS17400	COG0583	DNA-binding transcription factor activity
IEN91_RS17405	COG2828	Protein conserved in bacteria
IEN91_RS17410	COG0477	Major facilitator Superfamily
IEN91_RS17410	COG2814	Major facilitator Superfamily
IEN91_RS17415	COG1611	Belongs to the LOG family
IEN91_RS17420	COG1694	Mazg nucleotide pyrophosphohydrolase
IEN91_RS17425	COG0659	secondary active sulfate transmembrane transporter activity
IEN91_RS17430	COG0288	reversible hydration of carbon dioxide
IEN91_RS17435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEN91_RS17440	COG4290	ribonuclease
IEN91_RS17445	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IEN91_RS17450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEN91_RS17460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IEN91_RS17470	COG1051	belongs to the nudix hydrolase family
IEN91_RS17475	COG0492	ferredoxin-NADP+ reductase activity
IEN91_RS17480	COG0791	NLP P60 protein
IEN91_RS17480	COG3883	PFAM NLP P60 protein
IEN91_RS17485	COG0457	Tetratricopeptide repeat
IEN91_RS17490	COG5002	protein histidine kinase activity
IEN91_RS17495	COG0745	RESPONSE REGULATOR receiver
IEN91_RS17505	COG1132	(ABC) transporter
IEN91_RS17510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IEN91_RS17510	COG0140	phosphoribosyl-ATP diphosphatase activity
IEN91_RS17535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IEN91_RS17550	COG4990	cell redox homeostasis
IEN91_RS17555	COG0110	maltose O-acetyltransferase activity
IEN91_RS17575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IEN91_RS17585	COG2188	Transcriptional regulator
IEN91_RS17590	COG1309	transcriptional regulator
IEN91_RS17595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IEN91_RS17600	COG1950	PFAM Membrane protein of
IEN91_RS17605	COG1983	PspC domain protein
IEN91_RS17610	COG3595	metallopeptidase activity
IEN91_RS17625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IEN91_RS17635	COG4897	Protein conserved in bacteria
IEN91_RS17640	COG0574	Belongs to the PEP-utilizing enzyme family
IEN91_RS17640	COG3848	Pyruvate phosphate dikinase
IEN91_RS17645	COG1309	transcriptional regulator
IEN91_RS17650	COG2814	Major facilitator Superfamily
IEN91_RS17680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEN91_RS17690	COG3409	Peptidoglycan-binding domain 1 protein
IEN91_RS17690	COG0793	Belongs to the peptidase S41A family
IEN91_RS17695	COG3420	alginic acid biosynthetic process
IEN91_RS17700	COG2177	Part of the ABC transporter FtsEX involved in
IEN91_RS17705	COG2884	Cell division ATP-binding protein ftsE
IEN91_RS17710	COG2010	Cytochrome c
IEN91_RS17715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEN91_RS17730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IEN91_RS17745	COG1516	flagellar protein fliS
IEN91_RS17750	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IEN91_RS17755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IEN91_RS17775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IEN91_RS17780	COG4786	Flagellar basal body rod
IEN91_RS17780	COG1256	bacterial-type flagellum assembly
IEN91_RS17785	COG3418	PFAM FlgN family protein
IEN91_RS17790	COG2747	anti-sigma28 factor FlgM
IEN91_RS17800	COG1040	competence protein
IEN91_RS17810	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IEN91_RS17815	COG1307	EDD domain protein, DegV family
IEN91_RS17820	COG2197	response regulator
IEN91_RS17825	COG4585	Histidine kinase
IEN91_RS17830	COG1739	Uncharacterized protein family UPF0029
IEN91_RS17835	COG1316	TRANSCRIPTIONal
IEN91_RS17840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IEN91_RS17845	COG0438	transferase activity, transferring glycosyl groups
IEN91_RS17850	COG1215	transferase activity, transferring glycosyl groups
IEN91_RS17855	COG3206	protein involved in exopolysaccharide biosynthesis
IEN91_RS17860	COG3307	-O-antigen
IEN91_RS17865	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IEN91_RS17870	COG0438	transferase activity, transferring glycosyl groups
IEN91_RS17870	COG0297	glycogen (starch) synthase activity
IEN91_RS17875	COG2244	polysaccharide biosynthetic process
IEN91_RS17885	COG0860	N-Acetylmuramoyl-L-alanine amidase
IEN91_RS17885	COG2247	cell wall binding repeat
IEN91_RS17890	COG2385	sporulation resulting in formation of a cellular spore
IEN91_RS17890	COG2247	cell wall binding repeat
IEN91_RS17900	COG1316	TRANSCRIPTIONal
IEN91_RS17905	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IEN91_RS17910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IEN91_RS17915	COG1134	teichoic acid transport
IEN91_RS17920	COG1682	transport, permease protein
IEN91_RS17925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IEN91_RS17935	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IEN91_RS17940	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IEN91_RS17945	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IEN91_RS17950	COG4193	domain, Protein
IEN91_RS17955	COG1482	cell wall glycoprotein biosynthetic process
IEN91_RS17960	COG0697	spore germination
IEN91_RS17965	COG0814	amino acid
IEN91_RS17975	COG1215	transferase activity, transferring glycosyl groups
IEN91_RS17980	COG2814	Major facilitator Superfamily
IEN91_RS17985	COG1316	TRANSCRIPTIONal
IEN91_RS17990	COG0561	phosphatase activity
IEN91_RS17995	COG2433	Pfam Transposase IS66
IEN91_RS18000	COG0791	NLP P60 protein
IEN91_RS18010	COG2843	Capsule synthesis protein
IEN91_RS18020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IEN91_RS18025	COG0697	spore germination
IEN91_RS18030	COG0814	amino acid
IEN91_RS18040	COG1609	Transcriptional regulator
IEN91_RS18045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEN91_RS18055	COG1129	ABC transporter
IEN91_RS18060	COG1172	Belongs to the binding-protein-dependent transport system permease family
IEN91_RS18065	COG1879	ABC-type sugar transport system periplasmic component
IEN91_RS18070	COG3103	Sh3 type 3 domain protein
IEN91_RS18075	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEN91_RS18080	COG3527	Alpha-acetolactate decarboxylase
IEN91_RS18085	COG0028	Belongs to the TPP enzyme family
IEN91_RS18090	COG0583	DNA-binding transcription factor activity
IEN91_RS18095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IEN91_RS18110	COG5337	Spore coat protein CotH
IEN91_RS18120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEN91_RS18130	COG0405	Gamma-glutamyltransferase
IEN91_RS18135	COG1522	sequence-specific DNA binding
IEN91_RS18140	COG2059	Chromate
IEN91_RS18145	COG2059	Chromate
IEN91_RS18155	COG0655	NAD(P)H dehydrogenase (quinone) activity
IEN91_RS18160	COG0583	DNA-binding transcription factor activity
IEN91_RS18200	COG5444	nuclease activity
IEN91_RS18215	COG3878	Protein conserved in bacteria
IEN91_RS18220	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IEN91_RS18225	COG4464	protein tyrosine phosphatase activity
IEN91_RS18230	COG0489	protein tyrosine kinase activity
IEN91_RS18235	COG3944	biosynthesis protein
IEN91_RS18245	COG4715	Zinc finger, swim domain protein
IEN91_RS18250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IEN91_RS18255	COG0561	phosphatase activity
IEN91_RS18260	COG1349	DNA-binding transcription factor activity
IEN91_RS18265	COG0629	single-stranded DNA binding
IEN91_RS18290	COG0457	Tetratricopeptide repeat
IEN91_RS18295	COG4786	Flagellar basal body rod
IEN91_RS18300	COG4786	Flagellar basal body rod
IEN91_RS18305	COG1077	Cell shape determining protein MreB Mrl
IEN91_RS18310	COG1609	Transcriptional regulator
IEN91_RS18315	COG1846	Transcriptional regulator
IEN91_RS18320	COG2814	Major facilitator Superfamily
IEN91_RS18325	COG1953	Uracil, thiamine, allantoin
IEN91_RS18330	COG0477	Major facilitator Superfamily
IEN91_RS18335	COG1335	isochorismatase
IEN91_RS18340	COG0004	ammonium transporteR
IEN91_RS18345	COG0347	Belongs to the P(II) protein family
IEN91_RS18350	COG0772	Belongs to the SEDS family
IEN91_RS18355	COG0671	phosphoesterase, PA-phosphatase related
IEN91_RS18365	COG0739	heme binding
IEN91_RS18370	COG1247	-acetyltransferase
IEN91_RS18385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEN91_RS18400	COG0726	polysaccharide deacetylase
IEN91_RS18410	COG1959	2 iron, 2 sulfur cluster binding
IEN91_RS18425	COG0831	urea catabolic process
IEN91_RS18430	COG3237	CsbD-like
IEN91_RS18435	COG1994	Peptidase M50
IEN91_RS18440	COG0457	Tetratricopeptide repeat
IEN91_RS18450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IEN91_RS18460	COG2304	oxidoreductase activity
IEN91_RS18465	COG2304	oxidoreductase activity
IEN91_RS18470	COG2385	sporulation resulting in formation of a cellular spore
IEN91_RS18475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEN91_RS18485	COG4836	Membrane
IEN91_RS18555	COG0698	ribose 5-phosphate isomerase
IEN91_RS18560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEN91_RS18570	COG0009	L-threonylcarbamoyladenylate synthase
IEN91_RS18575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IEN91_RS18595	COG2890	protein-(glutamine-N5) methyltransferase activity
IEN91_RS18600	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IEN91_RS18605	COG0346	lactoylglutathione lyase activity
IEN91_RS18610	COG0789	Transcriptional regulator
IEN91_RS18615	COG0679	Auxin Efflux Carrier
IEN91_RS18620	COG0281	malic enzyme
IEN91_RS18635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IEN91_RS18640	COG1494	fructose-1,6-bisphosphatase
IEN91_RS18645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEN91_RS18655	COG0191	fructose-bisphosphate aldolase activity
IEN91_RS18660	COG2204	response regulator
IEN91_RS18665	COG4821	SIS domain
IEN91_RS18680	COG2181	nitrate reductase activity
IEN91_RS18680	COG0247	lactate metabolic process
IEN91_RS18685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEN91_RS18700	COG1132	(ABC) transporter
IEN91_RS18705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEN91_RS18715	COG2181	nitrate reductase activity
IEN91_RS18720	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IEN91_RS18725	COG1140	nitrate reductase beta subunit
IEN91_RS18730	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IEN91_RS18735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IEN91_RS18745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IEN91_RS18750	COG2223	nitrite transmembrane transporter activity
IEN91_RS18760	COG4506	Protein conserved in bacteria
IEN91_RS18765	COG0457	Tetratricopeptide repeat
IEN91_RS18800	COG0010	Belongs to the arginase family
IEN91_RS18805	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IEN91_RS18810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IEN91_RS18825	COG1994	Peptidase M50
IEN91_RS18830	COG1942	4-Oxalocrotonate Tautomerase
IEN91_RS18835	COG1846	Transcriptional regulator
IEN91_RS18840	COG0531	amino acid
IEN91_RS18845	COG3465	dGTPase activity
IEN91_RS18850	COG1078	dGTPase activity
IEN91_RS18865	COG1695	Transcriptional regulator
IEN91_RS18875	COG1131	(ABC) transporter
IEN91_RS18880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IEN91_RS18910	COG0583	DNA-binding transcription factor activity
IEN91_RS18915	COG2855	membrane
IEN91_RS18920	COG0280	phosphate acetyltransferase
IEN91_RS18930	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS18935	COG0436	Aminotransferase
IEN91_RS18965	COG2814	Major facilitator Superfamily
IEN91_RS18970	COG2814	Major facilitator Superfamily
IEN91_RS18975	COG0833	amino acid
IEN91_RS18980	COG4187	Peptidase family M20/M25/M40
IEN91_RS18985	COG1012	belongs to the aldehyde dehydrogenase family
IEN91_RS18990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IEN91_RS19000	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IEN91_RS19005	COG1091	dTDP-4-dehydrorhamnose reductase activity
IEN91_RS19010	COG1088	dTDP-glucose 4,6-dehydratase activity
IEN91_RS19015	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IEN91_RS19020	COG3980	spore coat polysaccharide biosynthesis protein
IEN91_RS19025	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
IEN91_RS19030	COG2089	acid synthase
IEN91_RS19035	COG0456	acetyltransferase
IEN91_RS19040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IEN91_RS19045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IEN91_RS19050	COG0463	Glycosyl transferase, family 2
IEN91_RS19060	COG2363	Small membrane protein
IEN91_RS19065	COG2233	PERMEase
IEN91_RS19080	COG1216	Glycosyl transferase, family 2
IEN91_RS19095	COG1695	Transcriptional regulator
IEN91_RS19100	COG0351	phosphomethylpyrimidine kinase
IEN91_RS19110	COG1621	beta-fructofuranosidase activity
IEN91_RS19115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IEN91_RS19115	COG1263	PTS System
IEN91_RS19120	COG3711	transcriptional antiterminator
IEN91_RS19130	COG1404	Belongs to the peptidase S8 family
IEN91_RS19135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEN91_RS19140	COG0778	Nitroreductase
IEN91_RS19145	COG0772	Belongs to the SEDS family
IEN91_RS19150	COG0454	-acetyltransferase
IEN91_RS19170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IEN91_RS19175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IEN91_RS19180	COG2261	transglycosylase associated protein
IEN91_RS19195	COG2246	polysaccharide biosynthetic process
IEN91_RS19200	COG1309	transcriptional regulator
IEN91_RS19220	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IEN91_RS19225	COG2837	iron assimilation
IEN91_RS19245	COG0583	DNA-binding transcription factor activity
IEN91_RS19255	COG1346	cytolysis
IEN91_RS19260	COG4895	conserved protein (DUF2196)
IEN91_RS19265	COG0789	Transcriptional regulator
IEN91_RS19270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IEN91_RS19275	COG0346	lactoylglutathione lyase activity
IEN91_RS19280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IEN91_RS19285	COG1404	Belongs to the peptidase S8 family
IEN91_RS19290	COG1442	glycosyl transferase family 8
IEN91_RS19295	COG2357	RelA SpoT domain protein
IEN91_RS19300	COG1575	Belongs to the MenA family. Type 1 subfamily
IEN91_RS19315	COG1696	Membrane protein involved in D-alanine export
IEN91_RS19325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IEN91_RS19330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IEN91_RS19335	COG1486	melibiose metabolic process
IEN91_RS19340	COG1447	Phosphotransferase system cellobiose-specific component IIA
IEN91_RS19345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IEN91_RS19350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IEN91_RS19355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEN91_RS19355	COG3711	transcriptional antiterminator
IEN91_RS19365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEN91_RS19370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEN91_RS19380	COG0640	Transcriptional regulator
IEN91_RS19385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IEN91_RS19390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IEN91_RS19395	COG1447	Phosphotransferase system cellobiose-specific component IIA
IEN91_RS19400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IEN91_RS19405	COG2723	6-phospho-beta-galactosidase activity
IEN91_RS19410	COG1940	carbohydrate kinase activity
IEN91_RS19415	COG1482	cell wall glycoprotein biosynthetic process
IEN91_RS19425	COG0753	catalase activity
IEN91_RS19430	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IEN91_RS19435	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IEN91_RS19440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IEN91_RS19445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IEN91_RS19450	COG4988	ABC transporter
IEN91_RS19455	COG1294	oxidase, subunit
IEN91_RS19460	COG1271	oxidase subunit
IEN91_RS19465	COG3493	citrate carrier protein
IEN91_RS19470	COG0726	polysaccharide deacetylase
IEN91_RS19475	COG3842	ATPase activity
IEN91_RS19480	COG2508	Transcriptional regulator
IEN91_RS19485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEN91_RS19495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IEN91_RS19510	COG4894	glucomannan catabolic process
IEN91_RS19515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IEN91_RS19520	COG0500	methyltransferase
IEN91_RS19525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IEN91_RS19540	COG0693	protein deglycase activity
IEN91_RS19540	COG0753	catalase activity
IEN91_RS19545	COG2851	Citrate transporter
IEN91_RS19550	COG2273	Hydrolase Family 16
IEN91_RS19560	COG2270	Major facilitator Superfamily
IEN91_RS19565	COG0513	Belongs to the DEAD box helicase family
IEN91_RS19635	COG0697	spore germination
IEN91_RS19640	COG0589	response to stress
IEN91_RS19650	COG0494	nUDIX hydrolase
IEN91_RS19655	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IEN91_RS19660	COG3507	Belongs to the glycosyl hydrolase 43 family
IEN91_RS19685	COG0010	Belongs to the arginase family
IEN91_RS19690	COG0833	amino acid
IEN91_RS19695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IEN91_RS19700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IEN91_RS19710	COG2390	Transcriptional regulator
IEN91_RS19715	COG0561	phosphatase activity
IEN91_RS19745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IEN91_RS19750	COG5294	Protein conserved in bacteria
IEN91_RS19755	COG0577	efflux transmembrane transporter activity
IEN91_RS19760	COG1136	(ABC) transporter
IEN91_RS19765	COG2205	protein histidine kinase activity
IEN91_RS19770	COG0745	RESPONSE REGULATOR receiver
IEN91_RS19775	COG2205	protein histidine kinase activity
IEN91_RS19780	COG0745	RESPONSE REGULATOR receiver
IEN91_RS19805	COG0745	RESPONSE REGULATOR receiver
IEN91_RS19835	COG1082	Xylose isomerase domain protein TIM barrel
IEN91_RS19845	COG2814	Major facilitator Superfamily
IEN91_RS19875	COG1349	DNA-binding transcription factor activity
IEN91_RS19880	COG0667	Aldo Keto reductase
IEN91_RS19885	COG2814	Major facilitator Superfamily
IEN91_RS19895	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS19900	COG2197	response regulator
IEN91_RS19905	COG4585	Histidine kinase
IEN91_RS19910	COG3239	Fatty acid desaturase
IEN91_RS19915	COG1309	transcriptional regulator
IEN91_RS19920	COG1012	belongs to the aldehyde dehydrogenase family
IEN91_RS19925	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IEN91_RS19935	COG0640	Transcriptional regulator
IEN91_RS19940	COG2814	Major facilitator Superfamily
IEN91_RS19945	COG1714	RDD family
IEN91_RS19960	COG0501	Belongs to the peptidase M48B family
IEN91_RS19965	COG1715	Restriction endonuclease
IEN91_RS19970	COG0450	alkyl hydroperoxide reductase
IEN91_RS19975	COG3634	alkyl hydroperoxide reductase activity
IEN91_RS19980	COG1113	amino acid transport
IEN91_RS19990	COG2080	2 iron, 2 sulfur cluster binding
IEN91_RS20005	COG2068	MobA-Related Protein
IEN91_RS20010	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IEN91_RS20065	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IEN91_RS20070	COG0667	Aldo Keto reductase
IEN91_RS20075	COG0456	acetyltransferase
IEN91_RS20080	COG0457	Tetratricopeptide repeat
IEN91_RS20085	COG0010	Belongs to the arginase family
IEN91_RS20090	COG0833	amino acid
IEN91_RS20095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IEN91_RS20100	COG5658	integral membrane protein
IEN91_RS20105	COG0640	Transcriptional regulator
IEN91_RS20110	COG3829	transcription factor binding
IEN91_RS20120	COG0488	(ABC) transporter
IEN91_RS20135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IEN91_RS20140	COG5002	protein histidine kinase activity
IEN91_RS20150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEN91_RS20155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IEN91_RS20160	COG4853	Protein conserved in bacteria
IEN91_RS20165	COG4863	YycH protein
IEN91_RS20170	COG5002	protein histidine kinase activity
IEN91_RS20175	COG0745	RESPONSE REGULATOR receiver
IEN91_RS20205	COG0346	lactoylglutathione lyase activity
IEN91_RS20210	COG0305	Participates in initiation and elongation during chromosome replication
IEN91_RS20225	COG3093	addiction module antidote protein HigA
IEN91_RS20230	COG0297	glycogen (starch) synthase activity
IEN91_RS20240	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IEN91_RS20245	COG0438	transferase activity, transferring glycosyl groups
IEN91_RS20255	COG0515	serine threonine protein kinase
IEN91_RS20265	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
IEN91_RS20270	COG4241	membrane
IEN91_RS20280	COG5577	PFAM Coat F domain
IEN91_RS20285	COG1733	regulation of RNA biosynthetic process
IEN91_RS20295	COG0697	spore germination
IEN91_RS20300	COG1621	beta-fructofuranosidase activity
IEN91_RS20305	COG1621	beta-fructofuranosidase activity
IEN91_RS20310	COG1802	Transcriptional regulator
IEN91_RS20315	COG2318	DinB family
IEN91_RS20320	COG2211	Major facilitator Superfamily
IEN91_RS20330	COG0778	Nitroreductase
IEN91_RS20335	COG1846	Transcriptional regulator
IEN91_RS20340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEN91_RS20345	COG1846	Transcriptional regulator
IEN91_RS20370	COG0583	DNA-binding transcription factor activity
IEN91_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
IEN91_RS20380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEN91_RS20385	COG0697	spore germination
IEN91_RS20390	COG1090	epimerase
IEN91_RS20400	COG1959	2 iron, 2 sulfur cluster binding
IEN91_RS20415	COG1331	Highly conserved protein containing a thioredoxin domain
IEN91_RS20420	COG1266	CAAX protease self-immunity
IEN91_RS20425	COG0477	Major facilitator Superfamily
IEN91_RS20425	COG2814	Major facilitator Superfamily
IEN91_RS20430	COG0346	lactoylglutathione lyase activity
IEN91_RS20435	COG1609	Transcriptional regulator
IEN91_RS20440	COG0708	Exodeoxyribonuclease III
IEN91_RS20445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEN91_RS20450	COG2169	Transcriptional regulator
IEN91_RS20460	COG0629	single-stranded DNA binding
IEN91_RS20470	COG0012	GTP binding
IEN91_RS20475	COG0243	molybdopterin cofactor binding
IEN91_RS20480	COG4481	Protein conserved in bacteria
IEN91_RS20485	COG3949	Membrane
IEN91_RS20500	COG1475	DNA binding
IEN91_RS20505	COG1192	Involved in chromosome partitioning
IEN91_RS20530	COG1847	R3H domain protein
IEN91_RS20535	COG0706	membrane insertase activity
IEN91_RS20570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IEN91_RS20575	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IEN91_RS20590	COG1091	dTDP-4-dehydrorhamnose reductase activity
IEN91_RS20595	COG1088	dTDP-glucose 4,6-dehydratase activity
IEN91_RS20650	COG1192	Involved in chromosome partitioning
IEN91_RS20675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEN91_RS20695	COG1215	transferase activity, transferring glycosyl groups
IEN91_RS20705	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane