locus-tag	class	description
F3129_RS00010	COG0592	DNA-directed DNA polymerase activity
F3129_RS00015	COG2501	S4 domain
F3129_RS00030	COG0187	DNA topoisomerase II activity
F3129_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3129_RS00070	COG0516	GMP reductase activity
F3129_RS00070	COG0517	IMP dehydrogenase activity
F3129_RS00075	COG1686	Belongs to the peptidase S11 family
F3129_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
F3129_RS00105	COG1428	Deoxynucleoside kinase
F3129_RS00110	COG1428	Deoxynucleoside kinase
F3129_RS00115	COG1388	LysM domain
F3129_RS00115	COG3858	chitin binding
F3129_RS00120	COG1335	isochorismatase
F3129_RS00125	COG0590	tRNA wobble adenosine to inosine editing
F3129_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F3129_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F3129_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
F3129_RS00195	COG3853	Toxic anion resistance protein (TelA)
F3129_RS00200	COG1982	Orn Lys Arg decarboxylase major
F3129_RS00210	COG3870	Protein conserved in bacteria
F3129_RS00215	COG1728	Protein conserved in bacteria
F3129_RS00220	COG0470	DNA polymerase III
F3129_RS00225	COG1774	PSP1 C-terminal conserved region
F3129_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
F3129_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F3129_RS00250	COG2002	toxin-antitoxin pair type II binding
F3129_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3129_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3129_RS00260	COG0084	hydrolase, TatD family'
F3129_RS00265	COG3583	domain protein
F3129_RS00265	COG3584	3D domain protein
F3129_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
F3129_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F3129_RS00285	COG4466	Protein conserved in bacteria
F3129_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F3129_RS00305	COG0251	oxidation-reduction process
F3129_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F3129_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F3129_RS00345	COG2002	toxin-antitoxin pair type II binding
F3129_RS00350	COG2244	polysaccharide biosynthetic process
F3129_RS00355	COG3956	TIGRFAM MazG family protein
F3129_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F3129_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F3129_RS00380	COG1098	S1 RNA binding domain
F3129_RS00395	COG2208	phosphoserine phosphatase activity
F3129_RS00400	COG2304	oxidoreductase activity
F3129_RS00405	COG0515	serine threonine protein kinase
F3129_RS00410	COG0037	tRNA processing
F3129_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
F3129_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3129_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3129_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3129_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3129_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
F3129_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3129_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F3129_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F3129_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F3129_RS00475	COG1396	sequence-specific DNA binding
F3129_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3129_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F3129_RS00565	COG4463	regulation of RNA biosynthetic process
F3129_RS00570	COG3880	PFAM UvrB UvrC protein
F3129_RS00580	COG0542	response to heat
F3129_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F3129_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
F3129_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
F3129_RS00615	COG1045	serine acetyltransferase
F3129_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
F3129_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3129_RS00635	COG3688	RNA-binding protein containing a PIN domain
F3129_RS00640	COG1595	DNA-templated transcription, initiation
F3129_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3129_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
F3129_RS00680	COG2813	Specifically methylates the guanine in position
F3129_RS00695	COG1358	cellular component organization or biogenesis
F3129_RS00720	COG0596	Alpha beta hydrolase
F3129_RS00830	COG0201	protein transport
F3129_RS00840	COG0024	Methionine aminopeptidase
F3129_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F3129_RS00880	COG1122	ATPase activity
F3129_RS00885	COG1122	ATPase activity
F3129_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F3129_RS00910	COG2226	methyltransferase
F3129_RS00915	COG2318	DinB family
F3129_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3129_RS00930	COG0489	protein tyrosine kinase activity
F3129_RS00940	COG2194	sulfuric ester hydrolase activity
F3129_RS00945	COG0726	polysaccharide deacetylase
F3129_RS01005	COG0738	Major facilitator superfamily
F3129_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3129_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
F3129_RS01030	COG0385	Bile acid
F3129_RS01035	COG2819	hydrolase of the alpha beta superfamily
F3129_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3129_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3129_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3129_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3129_RS01055	COG2207	Transcriptional regulator
F3129_RS01060	COG3876	Protein conserved in bacteria
F3129_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
F3129_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3129_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3129_RS01075	COG1263	PTS System
F3129_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3129_RS01090	COG1683	Conserved Protein
F3129_RS01120	COG1595	DNA-templated transcription, initiation
F3129_RS01125	COG5662	AntiSigma factor
F3129_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
F3129_RS01135	COG4856	YbbR-like protein
F3129_RS01175	COG1346	cytolysis
F3129_RS01180	COG1380	Effector of murein hydrolase LrgA
F3129_RS01185	COG1846	Transcriptional regulator
F3129_RS01190	COG1113	amino acid transport
F3129_RS01195	COG1011	Hydrolase
F3129_RS01200	COG4585	Histidine kinase
F3129_RS01205	COG2197	response regulator
F3129_RS01210	COG1131	(ABC) transporter
F3129_RS01250	COG0531	amino acid
F3129_RS01255	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F3129_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
F3129_RS01275	COG2271	Major facilitator Superfamily
F3129_RS01290	COG2368	4-hydroxyphenylacetate
F3129_RS01300	COG3409	Peptidoglycan-binding domain 1 protein
F3129_RS01315	COG0371	Dehydrogenase
F3129_RS01325	COG1183	phosphatidylcholine synthase activity
F3129_RS01330	COG0586	Pfam SNARE associated Golgi protein
F3129_RS01335	COG0688	phosphatidylethanolamine metabolic process
F3129_RS01350	COG1301	dicarboxylic acid transport
F3129_RS01355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3129_RS01360	COG0833	amino acid
F3129_RS01365	COG2040	homocysteine
F3129_RS01370	COG1115	amino acid carrier protein
F3129_RS01375	COG2066	Belongs to the glutaminase family
F3129_RS01380	COG4191	Histidine kinase
F3129_RS01385	COG0784	Response regulator, receiver
F3129_RS01390	COG3173	Aminoglycoside phosphotransferase
F3129_RS01400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3129_RS01405	COG0778	Nitroreductase
F3129_RS01410	COG0346	lactoylglutathione lyase activity
F3129_RS01415	COG2259	Doxx family
F3129_RS01420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3129_RS01435	COG3773	Cell wall hydrolase
F3129_RS01445	COG3540	Alkaline phosphatase
F3129_RS01450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3129_RS01455	COG0805	protein transport
F3129_RS01465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3129_RS01470	COG0477	Major facilitator Superfamily
F3129_RS01475	COG1309	transcriptional regulator
F3129_RS01480	COG0252	asparaginase activity
F3129_RS01485	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
F3129_RS01490	COG3012	SEC-C Motif Domain Protein
F3129_RS01490	COG1405	negative regulation of cell septum assembly
F3129_RS01495	COG0667	Aldo Keto reductase
F3129_RS01505	COG1595	DNA-templated transcription, initiation
F3129_RS01510	COG1595	DNA-templated transcription, initiation
F3129_RS01515	COG1876	peptidase activity
F3129_RS01520	COG0457	Tetratricopeptide repeat
F3129_RS01525	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS01530	COG0366	Alpha amylase catalytic
F3129_RS01535	COG0803	Belongs to the bacterial solute-binding protein 9 family
F3129_RS01540	COG1121	(ABC) transporter
F3129_RS01545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3129_RS01550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3129_RS01555	COG2310	stress, protein
F3129_RS01560	COG2310	stress, protein
F3129_RS01565	COG2310	stress, protein
F3129_RS01570	COG0861	Integral membrane protein TerC family
F3129_RS01580	COG3853	Toxic anion resistance protein (TelA)
F3129_RS01585	COG0477	Major facilitator Superfamily
F3129_RS01590	COG0517	IMP dehydrogenase activity
F3129_RS01590	COG4175	Glycine betaine
F3129_RS01595	COG4176	ABC-type proline glycine betaine transport system permease component
F3129_RS01600	COG2113	Glycine betaine
F3129_RS01605	COG1473	amidohydrolase
F3129_RS01610	COG1288	antiporter activity
F3129_RS01620	COG0366	Alpha amylase catalytic
F3129_RS01630	COG2814	Major facilitator Superfamily
F3129_RS01635	COG1846	Transcriptional regulator
F3129_RS01640	COG1280	lysine exporter protein (LysE YggA)
F3129_RS01645	COG3403	YqcI/YcgG family
F3129_RS01650	COG1113	amino acid transport
F3129_RS01655	COG3665	Urea carboxylase-associated protein
F3129_RS01670	COG1660	Displays ATPase and GTPase activities
F3129_RS01675	COG1082	Xylose isomerase domain protein TIM barrel
F3129_RS01680	COG2271	Major facilitator Superfamily
F3129_RS01685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F3129_RS01690	COG3458	cephalosporin-C deacetylase activity
F3129_RS01695	COG3541	Predicted nucleotidyltransferase
F3129_RS01700	COG0506	proline dehydrogenase activity
F3129_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
F3129_RS01710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3129_RS01715	COG2508	Transcriptional regulator
F3129_RS01725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F3129_RS01725	COG1587	Uroporphyrinogen-III synthase
F3129_RS01730	COG2146	nitrite reductase [NAD(P)H] activity
F3129_RS01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3129_RS01740	COG0243	molybdopterin cofactor binding
F3129_RS01745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3129_RS01750	COG2223	nitrite transmembrane transporter activity
F3129_RS01755	COG0523	cobalamin synthesis protein
F3129_RS01760	COG1063	alcohol dehydrogenase
F3129_RS01765	COG1714	RDD family
F3129_RS01775	COG2723	6-phospho-beta-galactosidase activity
F3129_RS01785	COG3209	COG3209 Rhs family protein
F3129_RS01790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F3129_RS01795	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
F3129_RS01800	COG1733	regulation of RNA biosynthetic process
F3129_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS01815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS01820	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
F3129_RS01835	COG0697	spore germination
F3129_RS01840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3129_RS01850	COG2364	Membrane
F3129_RS01855	COG1126	abc transporter atp-binding protein
F3129_RS01860	COG0765	amino acid transport
F3129_RS01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3129_RS01870	COG0583	DNA-binding transcription factor activity
F3129_RS01875	COG0163	prenyltransferase activity
F3129_RS01880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F3129_RS01895	COG3104	oligopeptide transport
F3129_RS01900	COG5434	Belongs to the glycosyl hydrolase 28 family
F3129_RS01910	COG0697	spore germination
F3129_RS01920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F3129_RS01925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3129_RS01930	COG0456	acetyltransferase
F3129_RS01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3129_RS01940	COG0765	amino acid transport
F3129_RS01945	COG1126	abc transporter atp-binding protein
F3129_RS01950	COG1473	amidohydrolase
F3129_RS01955	COG2079	MmgE PrpD family protein
F3129_RS01960	COG1136	(ABC) transporter
F3129_RS01965	COG0577	efflux transmembrane transporter activity
F3129_RS01970	COG0745	RESPONSE REGULATOR receiver
F3129_RS01975	COG5002	protein histidine kinase activity
F3129_RS01975	COG3850	Histidine kinase
F3129_RS01980	COG0457	Tetratricopeptide repeat
F3129_RS01995	COG0527	aspartate kinase activity
F3129_RS02000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3129_RS02005	COG4605	iron ion homeostasis
F3129_RS02010	COG4604	ABC transporter, ATP-binding protein
F3129_RS02015	COG4607	ABC-type enterochelin transport system periplasmic component
F3129_RS02020	COG2814	Major facilitator Superfamily
F3129_RS02025	COG1309	transcriptional regulator
F3129_RS02030	COG0778	Nitroreductase
F3129_RS02035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F3129_RS02040	COG0640	Transcriptional regulator
F3129_RS02045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3129_RS02050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3129_RS02055	COG1012	belongs to the aldehyde dehydrogenase family
F3129_RS02060	COG4975	Glucose uptake
F3129_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS02070	COG4549	nuclear export factor GLE1
F3129_RS02075	COG2372	response to copper ion
F3129_RS02075	COG1276	copper resistance
F3129_RS02080	COG1349	DNA-binding transcription factor activity
F3129_RS02090	COG2213	PTS system mannitol-specific
F3129_RS02095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3129_RS02105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3129_RS02115	COG0561	phosphatase activity
F3129_RS02125	COG1914	H( )-stimulated, divalent metal cation uptake system
F3129_RS02135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F3129_RS02140	COG1984	allophanate hydrolase subunit 2
F3129_RS02145	COG1414	Transcriptional regulator
F3129_RS02150	COG2755	lipolytic protein G-D-S-L family
F3129_RS02160	COG2329	Antibiotic biosynthesis monooxygenase
F3129_RS02165	COG0768	penicillin binding
F3129_RS02170	COG4989	oxidoreductase activity
F3129_RS02175	COG3711	transcriptional antiterminator
F3129_RS02180	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS02190	COG1917	Cupin 2, conserved barrel domain protein
F3129_RS02195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3129_RS02200	COG3871	stress protein (general stress protein 26)
F3129_RS02210	COG2814	Major facilitator Superfamily
F3129_RS02215	COG1522	sequence-specific DNA binding
F3129_RS02220	COG0551	DNA topoisomerase type I activity
F3129_RS02220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3129_RS02225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F3129_RS02230	COG3706	GGDEF domain
F3129_RS02235	COG5298	Protein conserved in bacteria
F3129_RS02240	COG1215	transferase activity, transferring glycosyl groups
F3129_RS02250	COG0531	amino acid
F3129_RS02255	COG0494	nUDIX hydrolase
F3129_RS02260	COG0028	Belongs to the TPP enzyme family
F3129_RS02285	COG1794	racemase activity, acting on amino acids and derivatives
F3129_RS02320	COG1914	H( )-stimulated, divalent metal cation uptake system
F3129_RS02335	COG4876	unkown
F3129_RS02345	COG2076	Multidrug Resistance protein
F3129_RS02350	COG2217	Heavy metal translocating P-type atpase
F3129_RS02355	COG3729	General stress protein
F3129_RS02360	COG0662	Cupin 2, conserved barrel domain protein
F3129_RS02365	COG2329	Antibiotic biosynthesis monooxygenase
F3129_RS02370	COG3546	catalase activity
F3129_RS02375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3129_RS02380	COG3290	protein histidine kinase activity
F3129_RS02385	COG4565	transcriptional regulatory protein
F3129_RS02390	COG1301	dicarboxylic acid transport
F3129_RS02395	COG0628	permease
F3129_RS02400	COG1131	(ABC) transporter
F3129_RS02405	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
F3129_RS02415	COG1960	acyl-CoA dehydrogenase activity
F3129_RS02430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3129_RS02435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3129_RS02445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F3129_RS02450	COG0513	Belongs to the DEAD box helicase family
F3129_RS02455	COG3402	PFAM membrane-flanked domain
F3129_RS02460	COG3428	Bacterial PH domain
F3129_RS02465	COG0705	Rhomboid family
F3129_RS02475	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F3129_RS02480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3129_RS02485	COG0864	Transcriptional regulator
F3129_RS02490	COG2337	Toxic component of a toxin-antitoxin (TA) module
F3129_RS02495	COG1366	Belongs to the anti-sigma-factor antagonist family
F3129_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
F3129_RS02505	COG2172	sigma factor antagonist activity
F3129_RS02510	COG2208	phosphoserine phosphatase activity
F3129_RS02515	COG1366	Belongs to the anti-sigma-factor antagonist family
F3129_RS02525	COG1191	sigma factor activity
F3129_RS02530	COG2208	phosphoserine phosphatase activity
F3129_RS02535	COG2183	response to ionizing radiation
F3129_RS02585	COG0582	viral genome integration into host DNA
F3129_RS02590	COG2856	Zn peptidase
F3129_RS02595	COG1396	sequence-specific DNA binding
F3129_RS02625	COG1674	ftsk spoiiie
F3129_RS02630	COG2946	Replication initiation factor
F3129_RS02680	COG0433	COG0433 Predicted ATPase
F3129_RS02690	COG5644	endopeptidase inhibitor activity
F3129_RS02695	COG0741	lytic transglycosylase activity
F3129_RS02695	COG0791	NLP P60 protein
F3129_RS02715	COG1204	response to ionizing radiation
F3129_RS02720	COG0457	Tetratricopeptide repeat
F3129_RS02730	COG5444	nuclease activity
F3129_RS02740	COG0604	alcohol dehydrogenase
F3129_RS02765	COG1959	2 iron, 2 sulfur cluster binding
F3129_RS02770	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3129_RS02775	COG1090	epimerase
F3129_RS02790	COG1733	regulation of RNA biosynthetic process
F3129_RS02795	COG2085	NADP oxidoreductase coenzyme F420-dependent
F3129_RS02800	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3129_RS02810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3129_RS02815	COG0477	Major facilitator Superfamily
F3129_RS02820	COG1846	Transcriptional regulator
F3129_RS02830	COG2030	dehydratase
F3129_RS02845	COG1959	2 iron, 2 sulfur cluster binding
F3129_RS02850	COG2910	NAD(P)H-binding
F3129_RS02855	COG1309	transcriptional regulator
F3129_RS02860	COG0300	oxidoreductase activity
F3129_RS02880	COG1278	Cold shock
F3129_RS02885	COG1329	Transcriptional regulator
F3129_RS02890	COG1794	racemase activity, acting on amino acids and derivatives
F3129_RS02905	COG3621	Patatin-like phospholipase
F3129_RS02915	COG0662	Cupin 2, conserved barrel domain protein
F3129_RS02930	COG0277	FAD linked oxidase domain protein
F3129_RS02955	COG0662	Cupin 2, conserved barrel domain protein
F3129_RS02965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3129_RS02990	COG1064	alcohol dehydrogenase
F3129_RS02995	COG0789	Transcriptional regulator
F3129_RS03005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3129_RS03040	COG2814	Major facilitator Superfamily
F3129_RS03045	COG1309	transcriptional regulator
F3129_RS03050	COG0697	spore germination
F3129_RS03055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3129_RS03060	COG5577	PFAM Coat F domain
F3129_RS03070	COG1063	alcohol dehydrogenase
F3129_RS03075	COG5577	PFAM Coat F domain
F3129_RS03085	COG0738	Major facilitator superfamily
F3129_RS03095	COG0110	maltose O-acetyltransferase activity
F3129_RS03105	COG2197	response regulator
F3129_RS03110	COG2409	Drug exporters of the RND superfamily
F3129_RS03115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F3129_RS03120	COG0488	(ABC) transporter
F3129_RS03125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3129_RS03130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3129_RS03140	COG2814	Major facilitator Superfamily
F3129_RS03145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3129_RS03155	COG0730	response to heat
F3129_RS03160	COG0456	acetyltransferase
F3129_RS03165	COG0789	Transcriptional regulator
F3129_RS03165	COG4978	Transcriptional regulator
F3129_RS03170	COG0697	spore germination
F3129_RS03175	COG1051	belongs to the nudix hydrolase family
F3129_RS03180	COG2226	methyltransferase
F3129_RS03185	COG0473	3-isopropylmalate dehydrogenase activity
F3129_RS03190	COG1802	Transcriptional regulator
F3129_RS03195	COG1819	glycosyl
F3129_RS03210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3129_RS03215	COG1388	LysM domain
F3129_RS03220	COG2814	Major facilitator Superfamily
F3129_RS03225	COG2188	Transcriptional regulator
F3129_RS03230	COG2186	Transcriptional regulator
F3129_RS03235	COG2807	transmembrane transport
F3129_RS03240	COG2076	Multidrug Resistance protein
F3129_RS03245	COG2076	Multidrug Resistance protein
F3129_RS03250	COG1309	transcriptional regulator
F3129_RS03255	COG0531	amino acid
F3129_RS03265	COG3832	glyoxalase III activity
F3129_RS03270	COG0604	alcohol dehydrogenase
F3129_RS03275	COG2814	Major facilitator Superfamily
F3129_RS03315	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F3129_RS03320	COG0802	atpase or kinase
F3129_RS03325	COG1214	PFAM Peptidase M22, glycoprotease
F3129_RS03330	COG0456	acetyltransferase
F3129_RS03335	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F3129_RS03340	COG0488	(ABC) transporter
F3129_RS03355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3129_RS03360	COG0805	protein transport
F3129_RS03370	COG1266	CAAX protease self-immunity
F3129_RS03400	COG0457	Tetratricopeptide repeat
F3129_RS03405	COG1063	alcohol dehydrogenase
F3129_RS03410	COG2211	Major facilitator Superfamily
F3129_RS03415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3129_RS03425	COG1842	Phage shock protein A
F3129_RS03430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F3129_RS03435	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F3129_RS03440	COG4260	virion core protein, lumpy skin disease virus
F3129_RS03445	COG2755	lipolytic protein G-D-S-L family
F3129_RS03445	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3129_RS03455	COG1595	DNA-templated transcription, initiation
F3129_RS03460	COG1063	alcohol dehydrogenase
F3129_RS03465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3129_RS03470	COG0823	Involved in the tonB-independent uptake of proteins
F3129_RS03480	COG2132	Multicopper oxidase
F3129_RS03485	COG1113	amino acid transport
F3129_RS03490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3129_RS03495	COG0714	Associated with various cellular activities
F3129_RS03500	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
F3129_RS03505	COG1305	Transglutaminase-like
F3129_RS03525	COG2252	PERMEase
F3129_RS03530	COG3064	Membrane
F3129_RS03550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F3129_RS03555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3129_RS03560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3129_RS03565	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F3129_RS03570	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3129_RS03585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3129_RS03595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F3129_RS03600	COG0138	bifunctional purine biosynthesis protein purh
F3129_RS03605	COG0151	Belongs to the GarS family
F3129_RS03615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3129_RS03620	COG1470	cell adhesion involved in biofilm formation
F3129_RS03625	COG4496	protein, YerC YecD
F3129_RS03630	COG0069	glutamate synthase activity
F3129_RS03640	COG0210	DNA helicase
F3129_RS03650	COG4851	CamS sex pheromone cAM373 precursor
F3129_RS03655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3129_RS03660	COG1285	pathogenesis
F3129_RS03665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3129_RS03685	COG1309	transcriptional regulator
F3129_RS03690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3129_RS03695	COG1597	lipid kinase activity
F3129_RS03700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F3129_RS03705	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F3129_RS03715	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F3129_RS03735	COG5444	nuclease activity
F3129_RS03745	COG5444	nuclease activity
F3129_RS03770	COG3546	catalase activity
F3129_RS03775	COG0454	-acetyltransferase
F3129_RS03785	COG2323	membrane
F3129_RS03790	COG2329	Antibiotic biosynthesis monooxygenase
F3129_RS03795	COG0346	lactoylglutathione lyase activity
F3129_RS03800	COG1366	Belongs to the anti-sigma-factor antagonist family
F3129_RS03805	COG5583	Uncharacterized small protein (DUF2292)
F3129_RS03810	COG0196	riboflavin kinase activity
F3129_RS03815	COG0670	Belongs to the BI1 family
F3129_RS03820	COG1846	Transcriptional regulator
F3129_RS03825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3129_RS03835	COG2124	cytochrome p450
F3129_RS03835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F3129_RS03840	COG1368	sulfuric ester hydrolase activity
F3129_RS03845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3129_RS03850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3129_RS03855	COG1442	glycosyl transferase family 8
F3129_RS03860	COG1216	Glycosyl transferase, family 2
F3129_RS03865	COG1442	glycosyl transferase family 8
F3129_RS03870	COG2223	nitrite transmembrane transporter activity
F3129_RS03875	COG0531	amino acid
F3129_RS03880	COG1012	belongs to the aldehyde dehydrogenase family
F3129_RS03885	COG0840	transmembrane signaling receptor activity
F3129_RS03890	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS03895	COG0457	Tetratricopeptide repeat
F3129_RS03895	COG0463	Glycosyl transferase, family 2
F3129_RS03900	COG0488	(ABC) transporter
F3129_RS03905	COG0789	Transcriptional regulator
F3129_RS03910	COG2814	Major facilitator Superfamily
F3129_RS03915	COG0488	(ABC) transporter
F3129_RS03920	COG0513	Belongs to the DEAD box helicase family
F3129_RS03930	COG2130	NADP-dependent
F3129_RS03945	COG3866	Pectate lyase
F3129_RS03950	COG0471	metal ion transport
F3129_RS03970	COG2972	Histidine kinase
F3129_RS03970	COG0745	RESPONSE REGULATOR receiver
F3129_RS03975	COG3279	Response regulator of the LytR AlgR family
F3129_RS03985	COG3764	Sortase (surface protein transpeptidase)
F3129_RS03990	COG3290	protein histidine kinase activity
F3129_RS03995	COG4565	transcriptional regulatory protein
F3129_RS04000	COG3181	Tripartite tricarboxylate transporter family receptor
F3129_RS04005	COG2851	Citrate transporter
F3129_RS04010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3129_RS04015	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
F3129_RS04025	COG2258	MOSC domain
F3129_RS04045	COG0024	Methionine aminopeptidase
F3129_RS04050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3129_RS04050	COG1263	PTS System
F3129_RS04060	COG1368	sulfuric ester hydrolase activity
F3129_RS04070	COG0071	Belongs to the small heat shock protein (HSP20) family
F3129_RS04085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3129_RS04085	COG1263	PTS System
F3129_RS04090	COG0366	Alpha amylase catalytic
F3129_RS04095	COG2188	Transcriptional regulator
F3129_RS04100	COG0778	Nitroreductase
F3129_RS04115	COG0737	Belongs to the 5'-nucleotidase family
F3129_RS04120	COG0693	protein deglycase activity
F3129_RS04125	COG1609	Transcriptional regulator
F3129_RS04140	COG2814	Major facilitator Superfamily
F3129_RS04150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3129_RS04155	COG4980	gas vesicle protein
F3129_RS04160	COG1295	ribonuclease BN
F3129_RS04165	COG0477	Major facilitator Superfamily
F3129_RS04170	COG0387	Pfam Sodium calcium exchanger
F3129_RS04180	COG0668	transmembrane transport
F3129_RS04185	COG0535	radical SAM domain protein
F3129_RS04195	COG0726	polysaccharide deacetylase
F3129_RS04200	COG2084	Dehydrogenase
F3129_RS04210	COG0598	Magnesium transport protein CorA
F3129_RS04215	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F3129_RS04220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F3129_RS04230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3129_RS04240	COG4637	Psort location Cytoplasmic, score
F3129_RS04245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3129_RS04250	COG0022	dehydrogenase e1 component
F3129_RS04255	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3129_RS04260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3129_RS04265	COG3284	Transcriptional regulator
F3129_RS04275	COG1486	melibiose metabolic process
F3129_RS04280	COG1737	Transcriptional regulator
F3129_RS04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3129_RS04285	COG1263	PTS System
F3129_RS04290	COG5434	Belongs to the glycosyl hydrolase 28 family
F3129_RS04295	COG1132	(ABC) transporter
F3129_RS04300	COG1132	(ABC) transporter
F3129_RS04305	COG2259	Doxx family
F3129_RS04310	COG2514	catechol 2,3-dioxygenase activity
F3129_RS04325	COG1695	Transcriptional regulator
F3129_RS04330	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3129_RS04335	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
F3129_RS04340	COG3848	Pyruvate phosphate dikinase
F3129_RS04340	COG0574	Belongs to the PEP-utilizing enzyme family
F3129_RS04345	COG2732	(Barnase) inhibitor
F3129_RS04350	COG2318	DinB family
F3129_RS04355	COG2814	Major facilitator Superfamily
F3129_RS04360	COG1846	Transcriptional regulator
F3129_RS04365	COG0392	lysyltransferase activity
F3129_RS04365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
F3129_RS04370	COG0384	phenazine biosynthesis protein PhzF
F3129_RS04375	COG0778	Nitroreductase
F3129_RS04390	COG1090	epimerase
F3129_RS04405	COG2814	Major facilitator Superfamily
F3129_RS04415	COG3591	Belongs to the peptidase S1B family
F3129_RS04430	COG3103	Sh3 type 3 domain protein
F3129_RS04435	COG5658	integral membrane protein
F3129_RS04440	COG0596	Alpha beta hydrolase
F3129_RS04445	COG0463	Glycosyl transferase, family 2
F3129_RS04450	COG4485	Bacterial membrane protein, YfhO
F3129_RS04455	COG1988	membrane-bound metal-dependent
F3129_RS04460	COG1194	a g-specific adenine glycosylase
F3129_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS04490	COG1132	(ABC) transporter
F3129_RS04495	COG4129	membrane
F3129_RS04505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F3129_RS04510	COG0735	belongs to the Fur family
F3129_RS04620	COG1757	Na H antiporter
F3129_RS04625	COG3340	Belongs to the peptidase S51 family
F3129_RS04635	COG0277	FAD linked oxidase domain protein
F3129_RS04645	COG0747	negative chemotaxis
F3129_RS04650	COG0601	transmembrane transport
F3129_RS04655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3129_RS04660	COG0444	Belongs to the ABC transporter superfamily
F3129_RS04665	COG4608	Belongs to the ABC transporter superfamily
F3129_RS04670	COG0753	catalase activity
F3129_RS04685	COG1116	anion transmembrane transporter activity
F3129_RS04690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3129_RS04695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3129_RS04715	COG1476	TRANSCRIPTIONal
F3129_RS04725	COG3382	B3 4 domain protein
F3129_RS04730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F3129_RS04740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3129_RS04745	COG0789	Transcriptional regulator
F3129_RS04750	COG1664	Polymer-forming cytoskeletal
F3129_RS04755	COG1664	Polymer-forming cytoskeletal
F3129_RS04760	COG2766	serine protein kinase
F3129_RS04775	COG1846	Transcriptional regulator
F3129_RS04780	COG1566	PFAM secretion protein HlyD family protein
F3129_RS04785	COG2814	Major facilitator Superfamily
F3129_RS04790	COG0655	NAD(P)H dehydrogenase (quinone) activity
F3129_RS04805	COG1725	Transcriptional regulator
F3129_RS04810	COG1131	(ABC) transporter
F3129_RS04815	COG1131	(ABC) transporter
F3129_RS04820	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
F3129_RS04825	COG1278	Cold shock
F3129_RS04835	COG1464	Belongs to the NlpA lipoprotein family
F3129_RS04840	COG3706	GGDEF domain
F3129_RS04845	COG1823	symporter activity
F3129_RS04865	COG5577	PFAM Coat F domain
F3129_RS04870	COG1525	nuclease
F3129_RS04870	COG0737	Belongs to the 5'-nucleotidase family
F3129_RS04870	COG4085	toxin activity
F3129_RS04875	COG3764	Sortase (surface protein transpeptidase)
F3129_RS04880	COG0564	pseudouridine synthase activity
F3129_RS04890	COG0517	IMP dehydrogenase activity
F3129_RS04895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3129_RS04900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3129_RS04900	COG3153	acetyltransferase
F3129_RS04905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3129_RS04910	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
F3129_RS04915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F3129_RS04925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3129_RS04930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3129_RS04935	COG4585	Histidine kinase
F3129_RS04935	COG2203	Gaf domain
F3129_RS04940	COG2197	response regulator
F3129_RS04945	COG0431	NADPH-dependent FMN reductase
F3129_RS04960	COG1388	LysM domain
F3129_RS04960	COG0791	NLP P60 protein
F3129_RS04965	COG1959	2 iron, 2 sulfur cluster binding
F3129_RS04975	COG0668	transmembrane transport
F3129_RS04980	COG2719	SpoVR family
F3129_RS04985	COG1785	Belongs to the alkaline phosphatase family
F3129_RS04990	COG0791	NLP P60 protein
F3129_RS04990	COG1388	LysM domain
F3129_RS04995	COG0583	DNA-binding transcription factor activity
F3129_RS05000	COG0372	Belongs to the citrate synthase family
F3129_RS05005	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS05010	COG0531	amino acid
F3129_RS05015	COG0733	neurotransmitter:sodium symporter activity
F3129_RS05030	COG1595	DNA-templated transcription, initiation
F3129_RS05035	COG0204	Acyl-transferase
F3129_RS05040	COG1253	flavin adenine dinucleotide binding
F3129_RS05045	COG0789	Transcriptional regulator
F3129_RS05050	COG0436	Aminotransferase
F3129_RS05055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3129_RS05060	COG1253	flavin adenine dinucleotide binding
F3129_RS05065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F3129_RS05070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F3129_RS05075	COG0584	glycerophosphoryl diester phosphodiesterase
F3129_RS05085	COG0668	transmembrane transport
F3129_RS05090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F3129_RS05095	COG0726	polysaccharide deacetylase
F3129_RS05100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3129_RS05105	COG3226	Transcriptional regulator
F3129_RS05115	COG0589	response to stress
F3129_RS05120	COG1132	(ABC) transporter
F3129_RS05125	COG1132	(ABC) transporter
F3129_RS05130	COG0702	epimerase
F3129_RS05150	COG0189	ligase activity
F3129_RS05155	COG0189	ligase activity
F3129_RS05170	COG4335	DNA alkylation repair
F3129_RS05175	COG0561	phosphatase activity
F3129_RS05180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3129_RS05190	COG0475	glutathione-regulated potassium exporter activity
F3129_RS05195	COG0490	domain, Protein
F3129_RS05205	COG1024	Enoyl-CoA hydratase
F3129_RS05215	COG4152	abc transporter atp-binding protein
F3129_RS05220	COG1668	transmembrane transport
F3129_RS05225	COG0420	3'-5' exonuclease activity
F3129_RS05230	COG4717	serine-type aminopeptidase activity
F3129_RS05245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3129_RS05285	COG4980	gas vesicle protein
F3129_RS05300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F3129_RS05305	COG0537	adenosine 5'-monophosphoramidase activity
F3129_RS05310	COG1131	(ABC) transporter
F3129_RS05315	COG4473	ABC transporter
F3129_RS05325	COG1473	amidohydrolase
F3129_RS05330	COG3069	C4-dicarboxylate transmembrane transporter activity
F3129_RS05335	COG2329	Antibiotic biosynthesis monooxygenase
F3129_RS05340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3129_RS05350	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F3129_RS05355	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
F3129_RS05360	COG1309	transcriptional regulator
F3129_RS05365	COG1511	domain protein
F3129_RS05370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3129_RS05380	COG1363	Peptidase, m42
F3129_RS05385	COG1301	dicarboxylic acid transport
F3129_RS05395	COG1234	tRNA 3'-trailer cleavage
F3129_RS05400	COG0095	Lipoate-protein ligase
F3129_RS05405	COG0702	epimerase
F3129_RS05410	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS05420	COG0501	Belongs to the peptidase M48B family
F3129_RS05425	COG1404	Belongs to the peptidase S8 family
F3129_RS05435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
F3129_RS05440	COG0406	alpha-ribazole phosphatase activity
F3129_RS05445	COG0183	Belongs to the thiolase family
F3129_RS05450	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS05455	COG1268	BioY protein
F3129_RS05460	COG0840	transmembrane signaling receptor activity
F3129_RS05465	COG0723	plastoquinol--plastocyanin reductase activity
F3129_RS05465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3129_RS05470	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS05480	COG4903	ComK protein
F3129_RS05490	COG5646	InterPro IPR014922
F3129_RS05515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3129_RS05530	COG0398	Pfam SNARE associated Golgi protein
F3129_RS05535	COG0681	Belongs to the peptidase S26 family
F3129_RS05540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3129_RS05545	COG1846	Transcriptional regulator
F3129_RS05550	COG3180	Ammonia monooxygenase
F3129_RS05555	COG2814	Major facilitator Superfamily
F3129_RS05565	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
F3129_RS05570	COG2323	membrane
F3129_RS05585	COG0420	3'-5' exonuclease activity
F3129_RS05590	COG0419	ATPase involved in DNA repair
F3129_RS05595	COG1403	HNH endonuclease
F3129_RS05635	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3129_RS05655	COG0367	asparagine synthase
F3129_RS05660	COG1562	ergosterol biosynthetic process
F3129_RS05665	COG0534	Mate efflux family protein
F3129_RS05670	COG1917	Cupin 2, conserved barrel domain protein
F3129_RS05670	COG2207	Transcriptional regulator
F3129_RS05675	COG2318	DinB family
F3129_RS05680	COG1279	arginine transmembrane transporter activity
F3129_RS05685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3129_RS05690	COG1357	PFAM Pentapeptide repeats (8 copies)
F3129_RS05695	COG2153	protein acetylation
F3129_RS05700	COG0646	methionine synthase
F3129_RS05700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F3129_RS05710	COG2996	Protein conserved in bacteria
F3129_RS05715	COG1744	ABC transporter substrate-binding protein PnrA-like
F3129_RS05720	COG0840	transmembrane signaling receptor activity
F3129_RS05725	COG2124	cytochrome p450
F3129_RS05735	COG1307	EDD domain protein, DegV family
F3129_RS05740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3129_RS05755	COG0561	phosphatase activity
F3129_RS05760	COG1073	alpha beta
F3129_RS05765	COG2151	metal-sulfur cluster biosynthetic enzyme
F3129_RS05775	COG0277	FAD linked oxidase domain protein
F3129_RS05780	COG2271	Major facilitator Superfamily
F3129_RS05790	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F3129_RS05800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3129_RS05805	COG0505	Belongs to the CarA family
F3129_RS05810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F3129_RS05815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F3129_RS05835	COG2267	carboxylic ester hydrolase activity
F3129_RS05845	COG1744	ABC transporter substrate-binding protein PnrA-like
F3129_RS05860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3129_RS05865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3129_RS05870	COG5504	Zn-dependent protease
F3129_RS05875	COG0444	Belongs to the ABC transporter superfamily
F3129_RS05880	COG4608	Belongs to the ABC transporter superfamily
F3129_RS05890	COG0601	transmembrane transport
F3129_RS05895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3129_RS05905	COG0180	Tryptophanyl-tRNA synthetase
F3129_RS05910	COG4166	transmembrane transport
F3129_RS05915	COG0601	transmembrane transport
F3129_RS05920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3129_RS05925	COG0444	Belongs to the ABC transporter superfamily
F3129_RS05930	COG4608	Belongs to the ABC transporter superfamily
F3129_RS05940	COG0456	acetyltransferase
F3129_RS05945	COG1393	Belongs to the ArsC family
F3129_RS05950	COG0861	Integral membrane protein TerC family
F3129_RS05955	COG4862	establishment of competence for transformation
F3129_RS05960	COG4469	Competence protein
F3129_RS05965	COG1164	Oligoendopeptidase f
F3129_RS05970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F3129_RS05975	COG2346	COG2346, Truncated hemoglobins
F3129_RS05980	COG0741	lytic transglycosylase activity
F3129_RS05985	COG4116	CYTH
F3129_RS05995	COG2357	RelA SpoT domain protein
F3129_RS06000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F3129_RS06005	COG0564	pseudouridine synthase activity
F3129_RS06020	COG0475	glutathione-regulated potassium exporter activity
F3129_RS06020	COG0569	domain protein
F3129_RS06025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F3129_RS06030	COG0352	thiamine-phosphate diphosphorylase activity
F3129_RS06035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3129_RS06040	COG2104	thiamine diphosphate biosynthetic process
F3129_RS06050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3129_RS06055	COG0351	phosphomethylpyrimidine kinase
F3129_RS06060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3129_RS06115	COG0210	DNA helicase
F3129_RS06135	COG1131	(ABC) transporter
F3129_RS06145	COG2153	protein acetylation
F3129_RS06155	COG2382	esterase
F3129_RS06160	COG0626	cystathionine gamma-synthase activity
F3129_RS06165	COG0626	cystathionine gamma-synthase activity
F3129_RS06175	COG0582	viral genome integration into host DNA
F3129_RS06180	COG2856	Zn peptidase
F3129_RS06240	COG3935	DnaD domain protein
F3129_RS06245	COG1484	DNA-dependent DNA replication
F3129_RS06280	COG1595	DNA-templated transcription, initiation
F3129_RS06315	COG5484	DNA packaging
F3129_RS06430	COG4824	toxin secretion phage lysis holin
F3129_RS06445	COG5444	nuclease activity
F3129_RS06490	COG5444	nuclease activity
F3129_RS06500	COG0346	lactoylglutathione lyase activity
F3129_RS06505	COG2367	Beta-lactamase
F3129_RS06510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F3129_RS06515	COG2814	Major facilitator Superfamily
F3129_RS06520	COG1846	Transcriptional regulator
F3129_RS06530	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
F3129_RS06535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3129_RS06540	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
F3129_RS06545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3129_RS06545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3129_RS06550	COG1447	Phosphotransferase system cellobiose-specific component IIA
F3129_RS06580	COG1285	pathogenesis
F3129_RS06595	COG2205	protein histidine kinase activity
F3129_RS06605	COG3383	formate dehydrogenase (NAD+) activity
F3129_RS06610	COG2427	Protein of unknown function (DUF1641)
F3129_RS06615	COG2124	cytochrome p450
F3129_RS06620	COG1819	glycosyl
F3129_RS06630	COG1587	Uroporphyrinogen-III synthase
F3129_RS06635	COG0390	transport system, permease component
F3129_RS06640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3129_RS06645	COG0697	spore germination
F3129_RS06650	COG4297	protein containing double-stranded beta helix domain
F3129_RS06660	COG1252	NADH dehydrogenase
F3129_RS06670	COG2211	Major facilitator Superfamily
F3129_RS06675	COG1609	Transcriptional regulator
F3129_RS06680	COG0246	Mannitol dehydrogenase
F3129_RS06685	COG2721	sulfolactate sulfo-lyase activity
F3129_RS06690	COG0745	RESPONSE REGULATOR receiver
F3129_RS06695	COG2205	protein histidine kinase activity
F3129_RS06695	COG2770	Histidine kinase
F3129_RS06715	COG4585	Histidine kinase
F3129_RS06720	COG2197	response regulator
F3129_RS06745	COG0730	response to heat
F3129_RS06750	COG2318	DinB family
F3129_RS06755	COG0457	Tetratricopeptide repeat
F3129_RS06765	COG3409	Peptidoglycan-binding domain 1 protein
F3129_RS06765	COG5632	N-Acetylmuramoyl-L-alanine amidase
F3129_RS06765	COG1388	LysM domain
F3129_RS06775	COG4195	phage-related replication protein
F3129_RS06780	COG2856	Zn peptidase
F3129_RS06785	COG1396	sequence-specific DNA binding
F3129_RS06795	COG1522	sequence-specific DNA binding
F3129_RS06800	COG1484	DNA-dependent DNA replication
F3129_RS06815	COG1595	DNA-templated transcription, initiation
F3129_RS06820	COG5484	DNA packaging
F3129_RS06820	COG3728	DNA packaging
F3129_RS06825	COG1783	phage Terminase large subunit
F3129_RS06830	COG5518	Phage portal protein
F3129_RS06835	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F3129_RS06840	COG4653	Phage capsid family
F3129_RS06890	COG3953	SLT domain
F3129_RS06890	COG5412	phage tail tape measure protein
F3129_RS06890	COG3953	SLT domain
F3129_RS06890	COG5412	phage tail tape measure protein
F3129_RS06890	COG5412	phage tail tape measure protein
F3129_RS06890	COG3953	SLT domain
F3129_RS06895	COG1652	LysM domain
F3129_RS06900	COG4193	domain, Protein
F3129_RS06910	COG3628	GPW Gp25 family protein
F3129_RS06915	COG3299	homolog of phage Mu protein gp47
F3129_RS06920	COG3778	Protein conserved in bacteria
F3129_RS06960	COG5632	N-Acetylmuramoyl-L-alanine amidase
F3129_RS06960	COG3409	Peptidoglycan-binding domain 1 protein
F3129_RS06975	COG0306	phosphate transporter
F3129_RS06980	COG1392	Phosphate transport regulator
F3129_RS06985	COG0531	amino acid
F3129_RS06990	COG0346	lactoylglutathione lyase activity
F3129_RS06995	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3129_RS07000	COG0463	Glycosyl transferase, family 2
F3129_RS07005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3129_RS07010	COG0477	Major facilitator Superfamily
F3129_RS07015	COG2362	D-Aminopeptidase
F3129_RS07020	COG0601	transmembrane transport
F3129_RS07025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3129_RS07030	COG0444	Belongs to the ABC transporter superfamily
F3129_RS07035	COG4166	transmembrane transport
F3129_RS07040	COG1619	proteins homologs of microcin C7 resistance protein MccF
F3129_RS07045	COG4948	Mandelate Racemase Muconate Lactonizing
F3129_RS07050	COG0791	NLP P60 protein
F3129_RS07055	COG4608	Belongs to the ABC transporter superfamily
F3129_RS07060	COG2706	6-phosphogluconolactonase activity
F3129_RS07065	COG1834	amidinotransferase
F3129_RS07070	COG1607	acyl-coa hydrolase
F3129_RS07075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3129_RS07080	COG2076	Multidrug Resistance protein
F3129_RS07085	COG2076	Multidrug Resistance protein
F3129_RS07090	COG0788	formyltetrahydrofolate deformylase activity
F3129_RS07095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F3129_RS07105	COG1764	response to oxidative stress
F3129_RS07110	COG1846	Transcriptional regulator
F3129_RS07115	COG1764	response to oxidative stress
F3129_RS07130	COG0457	Tetratricopeptide repeat
F3129_RS07130	COG0463	Glycosyl transferase, family 2
F3129_RS07140	COG2814	Major facilitator Superfamily
F3129_RS07145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3129_RS07155	COG1404	Belongs to the peptidase S8 family
F3129_RS07160	COG1366	Belongs to the anti-sigma-factor antagonist family
F3129_RS07165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F3129_RS07170	COG1122	ATPase activity
F3129_RS07175	COG4721	ABC-type cobalt transport system, permease component
F3129_RS07180	COG3858	chitin binding
F3129_RS07180	COG1388	LysM domain
F3129_RS07200	COG2239	Acts as a magnesium transporter
F3129_RS07205	COG0789	Transcriptional regulator
F3129_RS07220	COG1846	Transcriptional regulator
F3129_RS07225	COG0726	polysaccharide deacetylase
F3129_RS07230	COG1793	dna ligase
F3129_RS07230	COG3285	dna ligase
F3129_RS07235	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
F3129_RS07240	COG0586	Pfam SNARE associated Golgi protein
F3129_RS07245	COG0861	Integral membrane protein TerC family
F3129_RS07250	COG1191	sigma factor activity
F3129_RS07275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F3129_RS07280	COG2323	membrane
F3129_RS07290	COG3594	Acyltransferase
F3129_RS07295	COG5002	protein histidine kinase activity
F3129_RS07300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3129_RS07315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3129_RS07320	COG0436	Aminotransferase
F3129_RS07350	COG3852	Histidine kinase
F3129_RS07355	COG1846	Transcriptional regulator
F3129_RS07360	COG1360	Flagellar Motor Protein
F3129_RS07365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F3129_RS07370	COG0542	response to heat
F3129_RS07380	COG3949	Membrane
F3129_RS07395	COG0720	synthase
F3129_RS07400	COG0602	queuosine metabolic process
F3129_RS07410	COG1733	regulation of RNA biosynthetic process
F3129_RS07415	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS07430	COG4873	Protein conserved in bacteria
F3129_RS07440	COG3773	Cell wall hydrolase
F3129_RS07445	COG2244	polysaccharide biosynthetic process
F3129_RS07450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3129_RS07455	COG2217	Heavy metal translocating P-type atpase
F3129_RS07460	COG0006	proline dipeptidase activity
F3129_RS07465	COG1609	Transcriptional regulator
F3129_RS07470	COG3711	transcriptional antiterminator
F3129_RS07475	COG2190	(PTS) system
F3129_RS07475	COG1263	PTS System
F3129_RS07475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3129_RS07480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3129_RS07485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3129_RS07495	COG1533	DNA photolyase activity
F3129_RS07500	COG0840	transmembrane signaling receptor activity
F3129_RS07505	COG2084	Dehydrogenase
F3129_RS07515	COG0347	Belongs to the P(II) protein family
F3129_RS07520	COG2340	Cysteine-rich secretory protein family
F3129_RS07525	COG0768	penicillin binding
F3129_RS07530	COG4191	Histidine kinase
F3129_RS07535	COG0436	Aminotransferase
F3129_RS07545	COG0835	chemotaxis
F3129_RS07545	COG0784	Response regulator, receiver
F3129_RS07555	COG2814	Major facilitator Superfamily
F3129_RS07560	COG1376	ErfK ybiS ycfS ynhG family protein
F3129_RS07565	COG1408	metallophosphoesterase
F3129_RS07570	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS07580	COG2200	EAL domain
F3129_RS07585	COG4703	Protein of unknown function (DUF1797)
F3129_RS07590	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
F3129_RS07600	COG0517	IMP dehydrogenase activity
F3129_RS07605	COG0583	DNA-binding transcription factor activity
F3129_RS07610	COG0716	FMN binding
F3129_RS07620	COG0716	FMN binding
F3129_RS07640	COG0668	transmembrane transport
F3129_RS07645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3129_RS07665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3129_RS07670	COG0303	'Molybdopterin
F3129_RS07675	COG1763	Mo-molybdopterin cofactor biosynthetic process
F3129_RS07680	COG0314	molybdopterin synthase activity
F3129_RS07685	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F3129_RS07695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3129_RS07700	COG1136	(ABC) transporter
F3129_RS07705	COG0577	efflux transmembrane transporter activity
F3129_RS07710	COG1349	DNA-binding transcription factor activity
F3129_RS07715	COG1105	Belongs to the carbohydrate kinase PfkB family
F3129_RS07720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3129_RS07720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3129_RS07720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3129_RS07725	COG0681	Belongs to the peptidase S26 family
F3129_RS07735	COG0488	(ABC) transporter
F3129_RS07740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F3129_RS07745	COG2309	aminopeptidase activity
F3129_RS07755	COG1077	Cell shape determining protein MreB Mrl
F3129_RS07765	COG2002	toxin-antitoxin pair type II binding
F3129_RS07770	COG3852	Histidine kinase
F3129_RS07775	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F3129_RS07775	COG2105	PFAM AIG2 family protein
F3129_RS07780	COG0569	domain protein
F3129_RS07790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
F3129_RS07800	COG0561	phosphatase activity
F3129_RS07805	COG0242	peptide deformylase activity
F3129_RS07815	COG0497	DNA recombination
F3129_RS07830	COG4221	oxidoreductase activity
F3129_RS07830	COG3321	synthase
F3129_RS07830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS07830	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS07835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS07835	COG0300	oxidoreductase activity
F3129_RS07835	COG3321	synthase
F3129_RS07835	COG4221	oxidoreductase activity
F3129_RS07840	COG3321	synthase
F3129_RS07840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS07840	COG4221	oxidoreductase activity
F3129_RS07840	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS07845	COG3321	synthase
F3129_RS07845	COG0300	oxidoreductase activity
F3129_RS07845	COG4221	oxidoreductase activity
F3129_RS07845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS07850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS07850	COG4221	oxidoreductase activity
F3129_RS07850	COG3321	synthase
F3129_RS07850	COG0300	oxidoreductase activity
F3129_RS07855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS07855	COG0300	oxidoreductase activity
F3129_RS07855	COG3321	synthase
F3129_RS07855	COG4221	oxidoreductase activity
F3129_RS07860	COG4221	oxidoreductase activity
F3129_RS07860	COG3321	synthase
F3129_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS07860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS07865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3129_RS07870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3129_RS07875	COG0022	dehydrogenase e1 component
F3129_RS07880	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3129_RS07885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3129_RS07890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3129_RS07905	COG1982	Orn Lys Arg decarboxylase major
F3129_RS07930	COG0483	inositol monophosphate 1-phosphatase activity
F3129_RS07940	COG3227	Zinc metalloprotease (Elastase)
F3129_RS07945	COG1595	DNA-templated transcription, initiation
F3129_RS07965	COG1217	gtp-binding protein TYPA
F3129_RS07975	COG4896	Protein conserved in bacteria
F3129_RS07985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
F3129_RS07990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3129_RS07995	COG2066	Belongs to the glutaminase family
F3129_RS08005	COG0772	Belongs to the SEDS family
F3129_RS08010	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
F3129_RS08025	COG2010	Cytochrome c
F3129_RS08025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3129_RS08030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3129_RS08035	COG1845	cytochrome c oxidase, subunit III
F3129_RS08040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F3129_RS08045	COG3336	cytochrome c oxidase
F3129_RS08055	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
F3129_RS08060	COG2340	Cysteine-rich secretory protein family
F3129_RS08075	COG3679	Belongs to the UPF0342 family
F3129_RS08085	COG0742	ribosomal rna small subunit methyltransferase
F3129_RS08095	COG3314	Sporulation integral membrane protein YlbJ
F3129_RS08100	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3129_RS08105	COG3480	Lon protease (S16) C-terminal proteolytic domain
F3129_RS08115	COG1399	metal-binding, possibly nucleic acid-binding protein
F3129_RS08135	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F3129_RS08155	COG4839	cell division protein FtsL
F3129_RS08160	COG0768	penicillin binding
F3129_RS08165	COG0768	penicillin binding
F3129_RS08185	COG0772	Belongs to the SEDS family
F3129_RS08200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F3129_RS08205	COG0849	cell division
F3129_RS08210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3129_RS08215	COG1404	Belongs to the peptidase S8 family
F3129_RS08215	COG4412	M6 family metalloprotease domain protein
F3129_RS08225	COG1191	sigma factor activity
F3129_RS08230	COG1191	sigma factor activity
F3129_RS08235	COG1119	ATPase activity
F3129_RS08240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3129_RS08245	COG1873	PFAM PRC-barrel domain
F3129_RS08250	COG1496	oxidoreductase activity
F3129_RS08255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F3129_RS08265	COG0762	integral membrane protein
F3129_RS08270	COG2302	S4 RNA-binding domain
F3129_RS08275	COG3599	regulation of cell shape
F3129_RS08285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F3129_RS08290	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3129_RS08300	COG0564	pseudouridine synthase activity
F3129_RS08310	COG2233	PERMEase
F3129_RS08320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F3129_RS08325	COG0505	Belongs to the CarA family
F3129_RS08330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F3129_RS08345	COG0284	orotidine-5'-phosphate decarboxylase activity
F3129_RS08350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F3129_RS08360	COG0306	phosphate transporter
F3129_RS08375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F3129_RS08380	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
F3129_RS08385	COG1648	precorrin-2 dehydrogenase activity
F3129_RS08400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F3129_RS08405	COG1561	YicC-like family, N-terminal region
F3129_RS08415	COG0194	GDP metabolic process
F3129_RS08425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3129_RS08430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F3129_RS08435	COG0242	peptide deformylase activity
F3129_RS08445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3129_RS08445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F3129_RS08455	COG0631	protein serine/threonine phosphatase activity
F3129_RS08460	COG0515	serine threonine protein kinase
F3129_RS08460	COG2815	serine threonine protein kinase
F3129_RS08470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3129_RS08475	COG1564	THIamine pyrophosphokinase
F3129_RS08490	COG1302	Protein conserved in bacteria
F3129_RS08495	COG1461	Dihydroxyacetone kinase
F3129_RS08500	COG1760	l-serine dehydratase
F3129_RS08505	COG1760	l-serine dehydratase
F3129_RS08510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F3129_RS08525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F3129_RS08530	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS08545	COG1196	nuclear chromosome segregation
F3129_RS08550	COG0552	protein localization to endoplasmic reticulum
F3129_RS08565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F3129_RS08575	COG1837	Belongs to the UPF0109 family
F3129_RS08600	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
F3129_RS08615	COG2257	FlhB HrpN YscU SpaS Family
F3129_RS08625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3129_RS08630	COG0758	DNA mediated transformation
F3129_RS08635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3129_RS08645	COG4974	Belongs to the 'phage' integrase family
F3129_RS08665	COG1815	bacterial-type flagellum-dependent cell motility
F3129_RS08670	COG1558	bacterial-type flagellum-dependent cell motility
F3129_RS08675	COG1677	Flagellar hook-basal body complex protein FliE
F3129_RS08680	COG1766	The M ring may be actively involved in energy transduction
F3129_RS08685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3129_RS08690	COG1317	bacterial-type flagellum organization
F3129_RS08695	COG1157	protein secretion by the type III secretion system
F3129_RS08700	COG2882	bacterial-type flagellum organization
F3129_RS08705	COG3334	PFAM MgtE intracellular
F3129_RS08710	COG3144	bacterial-type flagellum assembly
F3129_RS08715	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F3129_RS08720	COG4786	Flagellar basal body rod
F3129_RS08725	COG1582	Flagellar protein (FlbD)
F3129_RS08730	COG1580	Controls the rotational direction of flagella during chemotaxis
F3129_RS08735	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3129_RS08740	COG1776	CheC inhibitor of MCP methylation
F3129_RS08740	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3129_RS08745	COG2201	protein-glutamate methylesterase activity
F3129_RS08750	COG3190	flagellar
F3129_RS08755	COG1338	Plays a role in the flagellum-specific transport system
F3129_RS08760	COG1987	bacterial-type flagellum assembly
F3129_RS08765	COG1684	flagellar biosynthetic protein fliR
F3129_RS08770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3129_RS08775	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3129_RS08780	COG1419	protein localization to endoplasmic reticulum
F3129_RS08785	COG0455	bacterial-type flagellum organization
F3129_RS08790	COG2201	protein-glutamate methylesterase activity
F3129_RS08795	COG2198	Histidine kinase
F3129_RS08795	COG0643	Histidine kinase
F3129_RS08800	COG0835	chemotaxis
F3129_RS08805	COG1776	CheC inhibitor of MCP methylation
F3129_RS08815	COG1191	sigma factor activity
F3129_RS08845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F3129_RS08850	COG4589	Belongs to the CDS family
F3129_RS08860	COG0750	zinc metalloprotease
F3129_RS08870	COG2176	DNA-directed DNA polymerase activity
F3129_RS08880	COG0195	Participates in both transcription termination and antitermination
F3129_RS08885	COG2740	Nucleic-acid-binding protein implicated in transcription termination
F3129_RS08890	COG1358	cellular component organization or biogenesis
F3129_RS08900	COG1550	Protein conserved in bacteria
F3129_RS08915	COG0196	riboflavin kinase activity
F3129_RS08930	COG0726	polysaccharide deacetylase
F3129_RS08935	COG0612	Peptidase, M16
F3129_RS08940	COG1873	PFAM PRC-barrel domain
F3129_RS08945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3129_RS08950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3129_RS08955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3129_RS08960	COG0527	aspartate kinase activity
F3129_RS08970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
F3129_RS08975	COG0740	serine-type endopeptidase activity
F3129_RS08985	COG1674	ftsk spoiiie
F3129_RS08985	COG4980	gas vesicle protein
F3129_RS08990	COG2188	Transcriptional regulator
F3129_RS08995	COG2814	Major facilitator Superfamily
F3129_RS09000	COG1846	Transcriptional regulator
F3129_RS09005	COG2409	Drug exporters of the RND superfamily
F3129_RS09005	COG1033	growth of symbiont in host cell
F3129_RS09010	COG0612	Peptidase, M16
F3129_RS09015	COG0612	Peptidase, M16
F3129_RS09020	COG0300	oxidoreductase activity
F3129_RS09035	COG1426	Protein conserved in bacteria
F3129_RS09040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3129_RS09055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3129_RS09065	COG1692	metallophosphoesterase
F3129_RS09070	COG2359	stage V sporulation protein S
F3129_RS09090	COG4550	Control of competence regulator ComK, YlbF/YmcA
F3129_RS09135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS09140	COG3425	synthase
F3129_RS09145	COG1024	Enoyl-CoA hydratase
F3129_RS09150	COG1024	Enoyl-CoA hydratase
F3129_RS09155	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS09155	COG0300	oxidoreductase activity
F3129_RS09155	COG3321	synthase
F3129_RS09155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS09160	COG0300	oxidoreductase activity
F3129_RS09160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS09160	COG3321	synthase
F3129_RS09160	COG4221	oxidoreductase activity
F3129_RS09165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS09165	COG3321	synthase
F3129_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS09165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS09165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3129_RS09165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3129_RS09165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS09165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS09165	COG3321	synthase
F3129_RS09170	COG4221	oxidoreductase activity
F3129_RS09170	COG3321	synthase
F3129_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS09170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS09175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS09175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F3129_RS09175	COG3321	synthase
F3129_RS09175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3129_RS09180	COG2124	cytochrome p450
F3129_RS09185	COG3209	COG3209 Rhs family protein
F3129_RS09190	COG3619	membrane
F3129_RS09205	COG1404	Belongs to the peptidase S8 family
F3129_RS09215	COG4195	phage-related replication protein
F3129_RS09220	COG1764	response to oxidative stress
F3129_RS09230	COG2076	Multidrug Resistance protein
F3129_RS09270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3129_RS09275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3129_RS09280	COG4112	unkown
F3129_RS09285	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3129_RS09295	COG0464	growth
F3129_RS09300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3129_RS09305	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
F3129_RS09310	COG0789	Transcriptional regulator
F3129_RS09315	COG0174	glutamine synthetase
F3129_RS09325	COG2211	Major facilitator Superfamily
F3129_RS09330	COG3507	Belongs to the glycosyl hydrolase 43 family
F3129_RS09345	COG1070	Carbohydrate kinase
F3129_RS09350	COG3848	Pyruvate phosphate dikinase
F3129_RS09350	COG0574	Belongs to the PEP-utilizing enzyme family
F3129_RS09380	COG1064	alcohol dehydrogenase
F3129_RS09405	COG0456	acetyltransferase
F3129_RS09435	COG3397	chitin binding
F3129_RS09455	COG5434	Belongs to the glycosyl hydrolase 28 family
F3129_RS09460	COG0756	dUTP diphosphatase activity
F3129_RS09470	COG4195	phage-related replication protein
F3129_RS09500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3129_RS09510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F3129_RS09530	COG0785	Cytochrome C biogenesis protein
F3129_RS09535	COG2201	protein-glutamate methylesterase activity
F3129_RS09540	COG4846	Membrane protein involved in cytochrome C biogenesis
F3129_RS09550	COG0071	Belongs to the small heat shock protein (HSP20) family
F3129_RS09565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3129_RS09570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3129_RS09590	COG0824	Thioesterase
F3129_RS09600	COG4841	protein insertion into membrane
F3129_RS09610	COG1832	CoA-binding protein
F3129_RS09615	COG0187	DNA topoisomerase II activity
F3129_RS09620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3129_RS09630	COG1115	amino acid carrier protein
F3129_RS09640	COG1063	alcohol dehydrogenase
F3129_RS09645	COG0800	Aldolase
F3129_RS09650	COG1312	Catalyzes the dehydration of D-mannonate
F3129_RS09655	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS09660	COG1609	Transcriptional regulator
F3129_RS09665	COG2271	Major facilitator Superfamily
F3129_RS09690	COG1136	(ABC) transporter
F3129_RS09690	COG0577	efflux transmembrane transporter activity
F3129_RS09720	COG2205	protein histidine kinase activity
F3129_RS09725	COG0745	RESPONSE REGULATOR receiver
F3129_RS09735	COG3507	Belongs to the glycosyl hydrolase 43 family
F3129_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS09765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3129_RS09770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F3129_RS09775	COG2610	gluconate transmembrane transporter activity
F3129_RS09780	COG2124	cytochrome p450
F3129_RS09800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3129_RS09810	COG2246	polysaccharide biosynthetic process
F3129_RS09815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3129_RS09820	COG0586	Pfam SNARE associated Golgi protein
F3129_RS09825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3129_RS09830	COG1024	Enoyl-CoA hydratase
F3129_RS09835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3129_RS09840	COG0511	ligase activity, forming carbon-carbon bonds
F3129_RS09845	COG0439	Biotin carboxylase
F3129_RS09850	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS09855	COG1960	acyl-CoA dehydrogenase activity
F3129_RS09860	COG1649	PFAM Uncharacterised BCR, COG1649
F3129_RS09870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS09870	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F3129_RS09875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS09880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS09885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS09890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS09900	COG2027	D-alanyl-D-alanine carboxypeptidase
F3129_RS09905	COG2017	converts alpha-aldose to the beta-anomer
F3129_RS09910	COG0534	Mate efflux family protein
F3129_RS09925	COG0582	viral genome integration into host DNA
F3129_RS09930	COG0166	Belongs to the GPI family
F3129_RS09935	COG0405	Gamma-glutamyltransferase
F3129_RS09940	COG2814	Major facilitator Superfamily
F3129_RS09945	COG0640	Transcriptional regulator
F3129_RS09950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F3129_RS09960	COG0604	alcohol dehydrogenase
F3129_RS09965	COG0493	'glutamate synthase
F3129_RS09970	COG0070	glutamate synthase
F3129_RS09970	COG0067	glutamate synthase
F3129_RS09970	COG0069	glutamate synthase activity
F3129_RS09975	COG0583	DNA-binding transcription factor activity
F3129_RS09980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F3129_RS10000	COG0300	oxidoreductase activity
F3129_RS10005	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
F3129_RS10015	COG2814	Major facilitator Superfamily
F3129_RS10020	COG1070	Carbohydrate kinase
F3129_RS10025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3129_RS10030	COG0243	molybdopterin cofactor binding
F3129_RS10065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3129_RS10070	COG2207	Transcriptional regulator
F3129_RS10070	COG0662	Cupin 2, conserved barrel domain protein
F3129_RS10075	COG1309	transcriptional regulator
F3129_RS10080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3129_RS10090	COG0640	Transcriptional regulator
F3129_RS10095	COG0741	lytic transglycosylase activity
F3129_RS10100	COG2322	membrane
F3129_RS10115	COG1619	proteins homologs of microcin C7 resistance protein MccF
F3129_RS10125	COG3584	3D domain protein
F3129_RS10125	COG1388	LysM domain
F3129_RS10130	COG0514	ATP-dependent DNA helicase (RecQ)
F3129_RS10140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3129_RS10145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3129_RS10160	COG0071	Belongs to the small heat shock protein (HSP20) family
F3129_RS10190	COG1012	belongs to the aldehyde dehydrogenase family
F3129_RS10195	COG1657	PFAM Prenyltransferase squalene oxidase
F3129_RS10200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3129_RS10205	COG0733	neurotransmitter:sodium symporter activity
F3129_RS10210	COG0385	Bile acid
F3129_RS10215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3129_RS10220	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3129_RS10230	COG4548	von Willebrand factor, type A
F3129_RS10235	COG0714	Associated with various cellular activities
F3129_RS10240	COG2032	superoxide dismutase activity
F3129_RS10245	COG0791	NLP P60 protein
F3129_RS10245	COG1388	LysM domain
F3129_RS10250	COG1819	glycosyl
F3129_RS10255	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
F3129_RS10260	COG0534	Mate efflux family protein
F3129_RS10265	COG1366	Belongs to the anti-sigma-factor antagonist family
F3129_RS10270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F3129_RS10275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F3129_RS10300	COG1942	4-Oxalocrotonate Tautomerase
F3129_RS10310	COG1733	regulation of RNA biosynthetic process
F3129_RS10315	COG0778	Nitroreductase
F3129_RS10320	COG0400	carboxylic ester hydrolase activity
F3129_RS10325	COG0346	lactoylglutathione lyase activity
F3129_RS10335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3129_RS10350	COG2723	6-phospho-beta-galactosidase activity
F3129_RS10355	COG2188	Transcriptional regulator
F3129_RS10360	COG3409	Peptidoglycan-binding domain 1 protein
F3129_RS10360	COG0793	Belongs to the peptidase S41A family
F3129_RS10365	COG2226	methyltransferase
F3129_RS10375	COG1876	peptidase activity
F3129_RS10395	COG0671	phosphoesterase, PA-phosphatase related
F3129_RS10425	COG1509	lysine 2,3-aminomutase activity
F3129_RS10430	COG0456	acetyltransferase
F3129_RS10435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3129_RS10440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3129_RS10445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F3129_RS10450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3129_RS10455	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F3129_RS10465	COG0456	acetyltransferase
F3129_RS10470	COG0463	Glycosyl transferase, family 2
F3129_RS10485	COG4641	Protein conserved in bacteria
F3129_RS10495	COG1086	Polysaccharide biosynthesis protein
F3129_RS10535	COG0457	Tetratricopeptide repeat
F3129_RS10545	COG1012	belongs to the aldehyde dehydrogenase family
F3129_RS10565	COG4282	regulation of fungal-type cell wall biogenesis
F3129_RS10570	COG1525	nuclease
F3129_RS10575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3129_RS10595	COG1846	Transcriptional regulator
F3129_RS10600	COG4698	Protein conserved in bacteria
F3129_RS10605	COG2755	lipolytic protein G-D-S-L family
F3129_RS10610	COG1999	signal sequence binding
F3129_RS10620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3129_RS10625	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F3129_RS10630	COG1272	protein, Hemolysin III
F3129_RS10635	COG0204	Acyl-transferase
F3129_RS10640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F3129_RS10655	COG2521	methyltransferase
F3129_RS10655	COG2136	Putative SAM-dependent methyltransferase
F3129_RS10670	COG1413	lyase activity
F3129_RS10675	COG1418	mRNA catabolic process
F3129_RS10680	COG0386	Belongs to the glutathione peroxidase family
F3129_RS10690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F3129_RS10700	COG1278	Cold shock
F3129_RS10720	COG0328	RNA-DNA hybrid ribonuclease activity
F3129_RS10725	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F3129_RS10730	COG0328	RNA-DNA hybrid ribonuclease activity
F3129_RS10740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3129_RS10755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
F3129_RS10765	COG1755	Isoprenylcysteine carboxyl methyltransferase
F3129_RS10770	COG3424	synthase
F3129_RS10790	COG2323	membrane
F3129_RS10795	COG1335	isochorismatase
F3129_RS10805	COG2233	PERMEase
F3129_RS10815	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F3129_RS10820	COG1199	ATP-dependent helicase activity
F3129_RS10835	COG0116	Belongs to the methyltransferase superfamily
F3129_RS10865	COG3359	exonuclease
F3129_RS10870	COG1205	dead DEAH box helicase
F3129_RS10870	COG1111	helicase
F3129_RS10875	COG2190	(PTS) system
F3129_RS10880	COG0071	Belongs to the small heat shock protein (HSP20) family
F3129_RS10920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3129_RS10920	COG4499	WXG100 protein secretion system (Wss), protein YukC
F3129_RS10930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F3129_RS10935	COG3935	DnaD domain protein
F3129_RS10945	COG0436	Aminotransferase
F3129_RS10950	COG5353	protein conserved in bacteria
F3129_RS10960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3129_RS10960	COG1199	ATP-dependent helicase activity
F3129_RS10990	COG0438	transferase activity, transferring glycosyl groups
F3129_RS10995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F3129_RS11010	COG1694	Mazg nucleotide pyrophosphohydrolase
F3129_RS11015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3129_RS11020	COG2140	Oxalate decarboxylase
F3129_RS11030	COG4347	Protein of unknown function (DUF1405)
F3129_RS11035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F3129_RS11035	COG2010	Cytochrome c
F3129_RS11040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F3129_RS11045	COG0723	plastoquinol--plastocyanin reductase activity
F3129_RS11060	COG0457	Tetratricopeptide repeat
F3129_RS11070	COG0287	Prephenate dehydrogenase
F3129_RS11105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3129_RS11110	COG4401	Chorismate mutase type I
F3129_RS11125	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F3129_RS11130	COG0105	UTP biosynthetic process
F3129_RS11135	COG0142	geranyltranstransferase activity
F3129_RS11145	COG0142	geranyltranstransferase activity
F3129_RS11160	COG0776	regulation of translation
F3129_RS11165	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
F3129_RS11205	COG0539	negative regulation of cytoplasmic translation
F3129_RS11215	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
F3129_RS11220	COG2959	enzyme of heme biosynthesis
F3129_RS11225	COG3409	Peptidoglycan-binding domain 1 protein
F3129_RS11225	COG3773	Cell wall hydrolase
F3129_RS11230	COG2339	peptidase activity
F3129_RS11235	COG0492	ferredoxin-NADP+ reductase activity
F3129_RS11240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3129_RS11245	COG4862	establishment of competence for transformation
F3129_RS11250	COG1408	metallophosphoesterase
F3129_RS11260	COG1388	LysM domain
F3129_RS11265	COG1266	CAAX protease self-immunity
F3129_RS11270	COG0514	ATP-dependent DNA helicase (RecQ)
F3129_RS11280	COG1141	Ferredoxin
F3129_RS11285	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
F3129_RS11290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3129_RS11300	COG1595	DNA-templated transcription, initiation
F3129_RS11305	COG5002	protein histidine kinase activity
F3129_RS11310	COG0745	RESPONSE REGULATOR receiver
F3129_RS11315	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3129_RS11320	COG1333	cytochrome c biogenesis protein
F3129_RS11325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3129_RS11330	COG1187	pseudouridine synthase activity
F3129_RS11335	COG0700	Nucleoside recognition
F3129_RS11340	COG2715	membrane protein required for spore maturation
F3129_RS11345	COG1686	Belongs to the peptidase S11 family
F3129_RS11370	COG1547	Domain of unknown function (DUF309)
F3129_RS11380	COG0456	acetyltransferase
F3129_RS11395	COG0307	riboflavin synthase, alpha
F3129_RS11400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3129_RS11400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3129_RS11410	COG0681	Belongs to the peptidase S26 family
F3129_RS11420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F3129_RS11425	COG4086	secreted protein
F3129_RS11430	COG0019	diaminopimelate decarboxylase activity
F3129_RS11435	COG0697	spore germination
F3129_RS11450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3129_RS11470	COG1191	sigma factor activity
F3129_RS11480	COG1366	Belongs to the anti-sigma-factor antagonist family
F3129_RS11485	COG1686	Belongs to the peptidase S11 family
F3129_RS11490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F3129_RS11495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F3129_RS11500	COG4974	Belongs to the 'phage' integrase family
F3129_RS11510	COG0735	belongs to the Fur family
F3129_RS11515	COG1300	Membrane
F3129_RS11530	COG0281	malic enzyme
F3129_RS11535	COG1757	Na H antiporter
F3129_RS11540	COG1027	Aspartate ammonia-lyase
F3129_RS11545	COG0252	asparaginase activity
F3129_RS11550	COG1396	sequence-specific DNA binding
F3129_RS11555	COG1379	DNA repair
F3129_RS11560	COG0494	nUDIX hydrolase
F3129_RS11570	COG0667	Aldo Keto reductase
F3129_RS11580	COG1073	alpha beta
F3129_RS11590	COG4918	Iron-sulphur cluster biosynthesis
F3129_RS11595	COG0456	acetyltransferase
F3129_RS11595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F3129_RS11600	COG2329	Antibiotic biosynthesis monooxygenase
F3129_RS11605	COG0456	acetyltransferase
F3129_RS11610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3129_RS11625	COG0628	permease
F3129_RS11635	COG0346	lactoylglutathione lyase activity
F3129_RS11645	COG3048	D-serine ammonia-lyase activity
F3129_RS11650	COG0300	oxidoreductase activity
F3129_RS11655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3129_RS11660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3129_RS11665	COG1024	Enoyl-CoA hydratase
F3129_RS11670	COG3425	synthase
F3129_RS11675	COG2124	cytochrome p450
F3129_RS11680	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS11680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS11680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3129_RS11680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS11680	COG3321	synthase
F3129_RS11685	COG3321	synthase
F3129_RS11685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3129_RS11685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS11685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS11690	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS11690	COG3321	synthase
F3129_RS11690	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS11690	COG0300	oxidoreductase activity
F3129_RS11690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS11695	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS11695	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS11695	COG3321	synthase
F3129_RS11695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS11695	COG0300	oxidoreductase activity
F3129_RS11700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3129_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS11700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS11700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS11700	COG3321	synthase
F3129_RS11705	COG3321	synthase
F3129_RS11705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS11705	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS11705	COG0300	oxidoreductase activity
F3129_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS11710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3129_RS11710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3129_RS11710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS11710	COG3321	synthase
F3129_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS11720	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS11735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F3129_RS11735	COG2070	2-Nitropropane dioxygenase
F3129_RS11745	COG0250	Participates in transcription elongation, termination and antitermination
F3129_RS11770	COG0596	Alpha beta hydrolase
F3129_RS11785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3129_RS11790	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F3129_RS11805	COG0706	membrane insertase activity
F3129_RS11810	COG2195	Cleaves the N-terminal amino acid of tripeptides
F3129_RS11815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3129_RS11820	COG0346	lactoylglutathione lyase activity
F3129_RS11830	COG1376	ErfK ybiS ycfS ynhG family protein
F3129_RS11835	COG4129	membrane
F3129_RS11840	COG1126	abc transporter atp-binding protein
F3129_RS11845	COG0765	amino acid transport
F3129_RS11850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3129_RS11860	COG1597	lipid kinase activity
F3129_RS11865	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3129_RS11870	COG0022	dehydrogenase e1 component
F3129_RS11875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3129_RS11880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3129_RS11885	COG3426	butyrate kinase activity
F3129_RS11890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3129_RS11895	COG0280	phosphate acetyltransferase
F3129_RS11900	COG3290	protein histidine kinase activity
F3129_RS11900	COG3829	transcription factor binding
F3129_RS11910	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
F3129_RS11915	COG2079	MmgE PrpD family protein
F3129_RS11920	COG0372	Belongs to the citrate synthase family
F3129_RS11925	COG1960	acyl-CoA dehydrogenase activity
F3129_RS11930	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3129_RS11935	COG0183	Belongs to the thiolase family
F3129_RS11940	COG0584	glycerophosphoryl diester phosphodiesterase
F3129_RS11945	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3129_RS11970	COG1902	pentaerythritol trinitrate reductase activity
F3129_RS11985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3129_RS11990	COG0745	RESPONSE REGULATOR receiver
F3129_RS11995	COG0750	zinc metalloprotease
F3129_RS12000	COG0497	DNA recombination
F3129_RS12010	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
F3129_RS12020	COG0142	geranyltranstransferase activity
F3129_RS12030	COG1570	exodeoxyribonuclease VII activity
F3129_RS12045	COG1302	Protein conserved in bacteria
F3129_RS12050	COG0439	Biotin carboxylase
F3129_RS12055	COG0511	ligase activity, forming carbon-carbon bonds
F3129_RS12095	COG3854	ATPases associated with a variety of cellular activities
F3129_RS12110	COG0006	proline dipeptidase activity
F3129_RS12120	COG3872	metal-dependent enzyme
F3129_RS12130	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3129_RS12145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3129_RS12165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F3129_RS12180	COG1396	sequence-specific DNA binding
F3129_RS12190	COG0681	Belongs to the peptidase S26 family
F3129_RS12215	COG4940	Competence protein ComGF
F3129_RS12225	COG4970	Tfp pilus assembly protein FimT
F3129_RS12230	COG4537	Required for transformation and DNA binding
F3129_RS12235	COG1459	type II secretion system
F3129_RS12240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3129_RS12245	COG0598	Magnesium transport protein CorA
F3129_RS12250	COG1253	flavin adenine dinucleotide binding
F3129_RS12255	COG1366	Belongs to the anti-sigma-factor antagonist family
F3129_RS12265	COG1393	Belongs to the ArsC family
F3129_RS12275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3129_RS12285	COG0011	TIGRFAM Protein of
F3129_RS12295	COG2866	Carboxypeptidase
F3129_RS12300	COG1940	carbohydrate kinase activity
F3129_RS12305	COG4483	Protein conserved in bacteria
F3129_RS12310	COG1757	Na H antiporter
F3129_RS12320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F3129_RS12335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3129_RS12340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3129_RS12345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3129_RS12350	COG0581	inorganic phosphate transmembrane transporter activity
F3129_RS12355	COG0573	inorganic phosphate transmembrane transporter activity
F3129_RS12360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F3129_RS12365	COG0768	penicillin binding
F3129_RS12370	COG0477	Major facilitator Superfamily
F3129_RS12375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3129_RS12380	COG2839	Protein conserved in bacteria
F3129_RS12385	COG5521	maltodextrose utilization protein MalA
F3129_RS12390	COG1388	LysM domain
F3129_RS12400	COG4709	membrane
F3129_RS12405	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
F3129_RS12410	COG0735	belongs to the Fur family
F3129_RS12415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3129_RS12430	COG0513	Belongs to the DEAD box helicase family
F3129_RS12450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F3129_RS12455	COG2384	SAM-dependent methyltransferase
F3129_RS12460	COG2010	Cytochrome c
F3129_RS12465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3129_RS12470	COG0358	DNA primase activity
F3129_RS12485	COG0517	IMP dehydrogenase activity
F3129_RS12490	COG0751	glycine-tRNA ligase activity
F3129_RS12510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F3129_RS12515	COG0295	cytidine deaminase activity
F3129_RS12520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F3129_RS12530	COG1480	7TM receptor with intracellular HD hydrolase
F3129_RS12535	COG1702	phosphate starvation-inducible protein PhoH
F3129_RS12540	COG0561	phosphatase activity
F3129_RS12555	COG4864	UPF0365 protein
F3129_RS12560	COG1030	water channel activity
F3129_RS12565	COG1610	YqeY-like protein
F3129_RS12575	COG1283	sodium-dependent phosphate transmembrane transporter activity
F3129_RS12580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3129_RS12585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F3129_RS12615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3129_RS12630	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3129_RS12645	COG1466	dna polymerase III delta subunit
F3129_RS12660	COG0658	competence protein
F3129_RS12660	COG2333	competence protein COMEC
F3129_RS12665	COG2131	deaminase
F3129_RS12670	COG1555	photosystem II stabilization
F3129_RS12670	COG1596	polysaccharide export
F3129_RS12675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3129_RS12680	COG2226	methyltransferase
F3129_RS12685	COG0799	negative regulation of ribosome biogenesis
F3129_RS12690	COG1713	HD superfamily hydrolase involved in NAD metabolism
F3129_RS12700	COG1534	Rna-binding protein
F3129_RS12705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3129_RS12710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
F3129_RS12715	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
F3129_RS12725	COG2755	lipolytic protein G-D-S-L family
F3129_RS12735	COG0398	Pfam SNARE associated Golgi protein
F3129_RS12775	COG3708	Transcriptional regulator
F3129_RS12775	COG2207	Transcriptional regulator
F3129_RS12785	COG0563	adenylate kinase activity
F3129_RS12805	COG2318	DinB family
F3129_RS12815	COG0561	phosphatase activity
F3129_RS12820	COG0561	phosphatase activity
F3129_RS12830	COG1482	cell wall glycoprotein biosynthetic process
F3129_RS12835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3129_RS12835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3129_RS12835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3129_RS12840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3129_RS12840	COG3711	transcriptional antiterminator
F3129_RS12850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3129_RS12855	COG0583	DNA-binding transcription factor activity
F3129_RS12860	COG2814	Major facilitator Superfamily
F3129_RS12865	COG2124	cytochrome p450
F3129_RS12865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F3129_RS12870	COG1309	transcriptional regulator
F3129_RS12875	COG2226	methyltransferase
F3129_RS12890	COG2116	formate transmembrane transporter activity
F3129_RS12895	COG5609	conserved protein (DUF2294)
F3129_RS12900	COG3383	formate dehydrogenase (NAD+) activity
F3129_RS12905	COG2427	Protein of unknown function (DUF1641)
F3129_RS12915	COG0626	cystathionine gamma-synthase activity
F3129_RS12920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3129_RS12945	COG0768	penicillin binding
F3129_RS12960	COG0826	peptidase U32
F3129_RS12965	COG0826	peptidase U32
F3129_RS12970	COG4122	O-methyltransferase activity
F3129_RS12975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3129_RS13000	COG0628	permease
F3129_RS13005	COG1126	abc transporter atp-binding protein
F3129_RS13010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3129_RS13015	COG0765	amino acid transport
F3129_RS13020	COG0765	amino acid transport
F3129_RS13035	COG3881	PFAM PRC-barrel domain
F3129_RS13040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3129_RS13045	COG0457	Tetratricopeptide repeat
F3129_RS13055	COG1104	cysteine desulfurase activity
F3129_RS13060	COG1959	2 iron, 2 sulfur cluster binding
F3129_RS13065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F3129_RS13070	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F3129_RS13090	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3129_RS13090	COG3103	Sh3 type 3 domain protein
F3129_RS13090	COG4991	sh3 domain protein
F3129_RS13100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F3129_RS13110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
F3129_RS13110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F3129_RS13115	COG5416	Lipopolysaccharide assembly protein A domain
F3129_RS13120	COG0490	domain, Protein
F3129_RS13125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F3129_RS13125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F3129_RS13135	COG2244	polysaccharide biosynthetic process
F3129_RS13140	COG2323	membrane
F3129_RS13150	COG1862	Preprotein translocase
F3129_RS13195	COG1388	LysM domain
F3129_RS13205	COG0157	Belongs to the NadC ModD family
F3129_RS13210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F3129_RS13215	COG1104	cysteine desulfurase activity
F3129_RS13220	COG1827	regulation of RNA biosynthetic process
F3129_RS13225	COG0077	Prephenate dehydratase
F3129_RS13240	COG3290	protein histidine kinase activity
F3129_RS13245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F3129_RS13250	COG2868	ribosomal protein
F3129_RS13260	COG1994	Peptidase M50
F3129_RS13265	COG0739	heme binding
F3129_RS13270	COG2894	cell division
F3129_RS13280	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F3129_RS13290	COG1077	Cell shape determining protein MreB Mrl
F3129_RS13310	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
F3129_RS13315	COG0285	dihydrofolate synthase activity
F3129_RS13320	COG0525	valine-tRNA ligase activity
F3129_RS13330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3129_RS13335	COG1388	LysM domain
F3129_RS13345	COG0113	porphobilinogen synthase activity
F3129_RS13350	COG1587	Uroporphyrinogen-III synthase
F3129_RS13360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3129_RS13380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3129_RS13385	COG1067	ATP-dependent peptidase activity
F3129_RS13385	COG0470	DNA polymerase III
F3129_RS13400	COG1477	protein flavinylation
F3129_RS13400	COG0457	Tetratricopeptide repeat
F3129_RS13415	COG0473	3-isopropylmalate dehydrogenase activity
F3129_RS13430	COG0440	acetolactate synthase activity
F3129_RS13435	COG0028	Belongs to the TPP enzyme family
F3129_RS13460	COG0622	Phosphoesterase
F3129_RS13465	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F3129_RS13475	COG5401	PFAM Sporulation and spore germination
F3129_RS13485	COG1846	Transcriptional regulator
F3129_RS13490	COG2197	response regulator
F3129_RS13495	COG0824	Thioesterase
F3129_RS13500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F3129_RS13505	COG1053	succinate dehydrogenase
F3129_RS13510	COG2009	succinate dehydrogenase
F3129_RS13515	COG1719	4-vinyl reductase, 4VR
F3129_RS13520	COG0527	aspartate kinase activity
F3129_RS13535	COG3118	belongs to the thioredoxin family
F3129_RS13540	COG3534	alpha-L-arabinofuranosidase
F3129_RS13545	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F3129_RS13550	COG2086	electron transfer activity
F3129_RS13555	COG1024	Enoyl-CoA hydratase
F3129_RS13560	COG1309	transcriptional regulator
F3129_RS13565	COG0318	PFAM AMP-dependent synthetase and ligase
F3129_RS13575	COG3766	membrane
F3129_RS13585	COG1796	DNA polymerase
F3129_RS13585	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
F3129_RS13590	COG1286	toxin biosynthetic process
F3129_RS13605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3129_RS13605	COG0072	phenylalanine-tRNA ligase activity
F3129_RS13610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F3129_RS13615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3129_RS13625	COG3835	regulator
F3129_RS13630	COG0277	FAD linked oxidase domain protein
F3129_RS13635	COG0247	lactate metabolic process
F3129_RS13640	COG1966	Carbon starvation protein
F3129_RS13645	COG3534	alpha-L-arabinofuranosidase
F3129_RS13650	COG0395	ABC-type sugar transport system, permease component
F3129_RS13655	COG1175	transmembrane transport
F3129_RS13660	COG1653	transport
F3129_RS13670	COG0647	UMP catabolic process
F3129_RS13675	COG0235	Class ii aldolase
F3129_RS13680	COG1069	ribulokinase activity
F3129_RS13685	COG2160	L-arabinose isomerase activity
F3129_RS13690	COG3507	Belongs to the glycosyl hydrolase 43 family
F3129_RS13695	COG1363	Peptidase, m42
F3129_RS13705	COG3326	Membrane
F3129_RS13720	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F3129_RS13725	COG1346	cytolysis
F3129_RS13730	COG1380	Effector of murein hydrolase LrgA
F3129_RS13735	COG3279	Response regulator of the LytR AlgR family
F3129_RS13740	COG3275	phosphorelay sensor kinase activity
F3129_RS13745	COG1011	Hydrolase
F3129_RS13760	COG0398	Pfam SNARE associated Golgi protein
F3129_RS13765	COG1484	DNA-dependent DNA replication
F3129_RS13770	COG3611	Membrane attachment protein
F3129_RS13785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F3129_RS13790	COG1733	regulation of RNA biosynthetic process
F3129_RS13795	COG2814	Major facilitator Superfamily
F3129_RS13800	COG0656	L-ascorbic acid biosynthetic process
F3129_RS13805	COG0237	dephospho-CoA kinase activity
F3129_RS13810	COG1971	Probably functions as a manganese efflux pump
F3129_RS13815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F3129_RS13820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3129_RS13820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3129_RS13825	COG5002	protein histidine kinase activity
F3129_RS13830	COG0745	RESPONSE REGULATOR receiver
F3129_RS13840	COG0538	isocitrate dehydrogenase activity
F3129_RS13845	COG0372	Belongs to the citrate synthase family
F3129_RS13850	COG0457	Tetratricopeptide repeat
F3129_RS13875	COG5632	N-Acetylmuramoyl-L-alanine amidase
F3129_RS13885	COG0628	permease
F3129_RS13890	COG3030	protein affecting phage T7 exclusion by the F plasmid
F3129_RS13895	COG0469	pyruvate kinase activity
F3129_RS13915	COG0281	malic enzyme
F3129_RS13920	COG0587	DNA-directed DNA polymerase activity
F3129_RS13940	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F3129_RS13950	COG4109	DRTGG domain
F3129_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS13975	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3129_RS13985	COG0827	DNA restriction-modification system
F3129_RS13990	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F3129_RS13995	COG3874	Sporulation protein YtfJ
F3129_RS14005	COG1714	RDD family
F3129_RS14010	COG0616	signal peptide processing
F3129_RS14015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F3129_RS14020	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F3129_RS14025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3129_RS14040	COG1104	cysteine desulfurase activity
F3129_RS14045	COG1114	Component of the transport system for branched-chain amino acids
F3129_RS14055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
F3129_RS14060	COG1309	transcriptional regulator
F3129_RS14065	COG1956	GAF domain-containing protein
F3129_RS14070	COG2199	diguanylate cyclase activity
F3129_RS14070	COG2203	Gaf domain
F3129_RS14085	COG1012	belongs to the aldehyde dehydrogenase family
F3129_RS14125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3129_RS14125	COG1017	nitric oxide dioxygenase activity
F3129_RS14140	COG0693	protein deglycase activity
F3129_RS14155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3129_RS14160	COG1378	Sugar-specific transcriptional regulator TrmB
F3129_RS14180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3129_RS14185	COG0454	-acetyltransferase
F3129_RS14190	COG0517	IMP dehydrogenase activity
F3129_RS14195	COG0123	including yeast histone deacetylase and acetoin utilization protein
F3129_RS14200	COG1360	Flagellar Motor Protein
F3129_RS14205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F3129_RS14210	COG1609	Transcriptional regulator
F3129_RS14215	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
F3129_RS14215	COG1605	Chorismate mutase
F3129_RS14220	COG3118	belongs to the thioredoxin family
F3129_RS14225	COG4980	gas vesicle protein
F3129_RS14230	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
F3129_RS14240	COG1674	ftsk spoiiie
F3129_RS14245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3129_RS14255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3129_RS14265	COG1363	Peptidase, m42
F3129_RS14270	COG5584	Small secreted protein
F3129_RS14275	COG0281	malic enzyme
F3129_RS14280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3129_RS14295	COG0510	thiamine kinase activity
F3129_RS14300	COG1597	lipid kinase activity
F3129_RS14310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F3129_RS14315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3129_RS14320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3129_RS14325	COG2252	PERMEase
F3129_RS14330	COG4473	ABC transporter
F3129_RS14335	COG1131	(ABC) transporter
F3129_RS14340	COG1349	DNA-binding transcription factor activity
F3129_RS14345	COG1187	pseudouridine synthase activity
F3129_RS14350	COG2244	polysaccharide biosynthetic process
F3129_RS14355	COG2081	HI0933 family
F3129_RS14360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3129_RS14370	COG1609	Transcriptional regulator
F3129_RS14375	COG1653	transport
F3129_RS14380	COG1175	transmembrane transport
F3129_RS14385	COG0395	ABC-type sugar transport system, permease component
F3129_RS14390	COG1486	melibiose metabolic process
F3129_RS14400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3129_RS14415	COG1366	Belongs to the anti-sigma-factor antagonist family
F3129_RS14415	COG2202	Pas domain
F3129_RS14420	COG2814	Major facilitator Superfamily
F3129_RS14425	COG5522	Integral membrane protein (intg_mem_TP0381)
F3129_RS14430	COG0577	efflux transmembrane transporter activity
F3129_RS14435	COG1136	(ABC) transporter
F3129_RS14440	COG2205	protein histidine kinase activity
F3129_RS14445	COG0745	RESPONSE REGULATOR receiver
F3129_RS14450	COG0577	efflux transmembrane transporter activity
F3129_RS14455	COG1136	(ABC) transporter
F3129_RS14475	COG1131	(ABC) transporter
F3129_RS14480	COG1725	Transcriptional regulator
F3129_RS14490	COG1242	4 iron, 4 sulfur cluster binding
F3129_RS14495	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F3129_RS14510	COG2267	carboxylic ester hydrolase activity
F3129_RS14515	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F3129_RS14520	COG1113	amino acid transport
F3129_RS14525	COG0367	asparagine synthase
F3129_RS14545	COG1506	peptidase
F3129_RS14550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3129_RS14555	COG1116	anion transmembrane transporter activity
F3129_RS14560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3129_RS14565	COG0494	nUDIX hydrolase
F3129_RS14570	COG4824	toxin secretion phage lysis holin
F3129_RS14575	COG0783	Belongs to the Dps family
F3129_RS14600	COG0288	reversible hydration of carbon dioxide
F3129_RS14610	COG1271	oxidase subunit
F3129_RS14615	COG1294	oxidase, subunit
F3129_RS14625	COG4948	Mandelate Racemase Muconate Lactonizing
F3129_RS14635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F3129_RS14640	COG0596	Alpha beta hydrolase
F3129_RS14650	COG1169	isochorismate synthase
F3129_RS14655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3129_RS14660	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
F3129_RS14785	COG3859	Proton-coupled thiamine transporter YuaJ
F3129_RS14790	COG2268	Band 7 protein
F3129_RS14795	COG1585	Membrane protein implicated in regulation of membrane protease activity
F3129_RS14800	COG2318	DinB family
F3129_RS14810	COG1454	alcohol dehydrogenase
F3129_RS14815	COG1012	belongs to the aldehyde dehydrogenase family
F3129_RS14820	COG1510	regulation of RNA biosynthetic process
F3129_RS14830	COG0569	domain protein
F3129_RS14835	COG1705	Flagellar rod assembly protein muramidase FlgJ
F3129_RS14840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3129_RS14840	COG1017	nitric oxide dioxygenase activity
F3129_RS14865	COG0628	permease
F3129_RS14870	COG0673	inositol 2-dehydrogenase activity
F3129_RS14875	COG0693	protein deglycase activity
F3129_RS14880	COG0840	transmembrane signaling receptor activity
F3129_RS14885	COG0840	transmembrane signaling receptor activity
F3129_RS14890	COG0840	transmembrane signaling receptor activity
F3129_RS14895	COG0840	transmembrane signaling receptor activity
F3129_RS14910	COG2070	2-Nitropropane dioxygenase
F3129_RS14915	COG0432	Pfam Uncharacterised protein family UPF0047
F3129_RS14920	COG0366	Alpha amylase catalytic
F3129_RS14925	COG1253	flavin adenine dinucleotide binding
F3129_RS14930	COG2738	Putative neutral zinc metallopeptidase
F3129_RS14945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3129_RS14975	COG1335	isochorismatase
F3129_RS14980	COG1979	alcohol dehydrogenase
F3129_RS14985	COG1979	alcohol dehydrogenase
F3129_RS14990	COG2155	Conserved Protein
F3129_RS14995	COG1098	S1 RNA binding domain
F3129_RS15000	COG0436	Aminotransferase
F3129_RS15005	COG1522	sequence-specific DNA binding
F3129_RS15010	COG2267	carboxylic ester hydrolase activity
F3129_RS15020	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F3129_RS15025	COG2205	protein histidine kinase activity
F3129_RS15035	COG5018	Exonuclease
F3129_RS15040	COG2814	Major facilitator Superfamily
F3129_RS15045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3129_RS15050	COG3011	Protein conserved in bacteria
F3129_RS15060	COG3290	protein histidine kinase activity
F3129_RS15065	COG4565	transcriptional regulatory protein
F3129_RS15070	COG1744	ABC transporter substrate-binding protein PnrA-like
F3129_RS15075	COG3845	ABC transporter
F3129_RS15080	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3129_RS15085	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3129_RS15095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3129_RS15095	COG2111	Na H antiporter
F3129_RS15100	COG2111	Na H antiporter
F3129_RS15105	COG1006	Multisubunit Na H antiporter MnhC subunit
F3129_RS15110	COG0651	ATP synthesis coupled electron transport
F3129_RS15115	COG1863	multisubunit Na H antiporter MnhE subunit
F3129_RS15120	COG2212	antiporter activity
F3129_RS15125	COG1320	monovalent cation:proton antiporter activity
F3129_RS15130	COG2050	protein possibly involved in aromatic compounds catabolism
F3129_RS15135	COG2197	response regulator
F3129_RS15140	COG4585	Histidine kinase
F3129_RS15170	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
F3129_RS15175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F3129_RS15180	COG1335	isochorismatase
F3129_RS15185	COG5506	Protein of unknown function (DUF1694)
F3129_RS15200	COG0628	permease
F3129_RS15210	COG1418	mRNA catabolic process
F3129_RS15215	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS15225	COG1511	domain protein
F3129_RS15230	COG0433	COG0433 Predicted ATPase
F3129_RS15230	COG1674	ftsk spoiiie
F3129_RS15235	COG4499	WXG100 protein secretion system (Wss), protein YukC
F3129_RS15240	COG5417	Belongs to the EsaB family
F3129_RS15245	COG4842	Belongs to the WXG100 family
F3129_RS15250	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
F3129_RS15250	COG2508	Transcriptional regulator
F3129_RS15255	COG0686	Belongs to the AlaDH PNT family
F3129_RS15260	COG5634	Uncharacterized conserved protein (DUF2278)
F3129_RS15265	COG3251	PFAM MbtH domain protein
F3129_RS15270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3129_RS15275	COG1535	isochorismatase
F3129_RS15275	COG3433	isochorismatase activity
F3129_RS15280	COG1021	2,3-dihydroxybenzoate-AMP ligase
F3129_RS15285	COG1169	isochorismate synthase
F3129_RS15290	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS15295	COG2819	hydrolase of the alpha beta superfamily
F3129_RS15300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3129_RS15305	COG1268	BioY protein
F3129_RS15310	COG2056	Na+-H+ antiporter family
F3129_RS15320	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
F3129_RS15325	COG3584	3D domain protein
F3129_RS15340	COG1252	NADH dehydrogenase
F3129_RS15370	COG1131	(ABC) transporter
F3129_RS15395	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
F3129_RS15400	COG0316	Belongs to the HesB IscA family
F3129_RS15410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3129_RS15420	COG1252	NADH dehydrogenase
F3129_RS15425	COG4837	Protein of unknown function (DUF1462)
F3129_RS15430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F3129_RS15435	COG1506	peptidase
F3129_RS15435	COG4946	Tricorn protease homolog
F3129_RS15435	COG0823	Involved in the tonB-independent uptake of proteins
F3129_RS15445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F3129_RS15450	COG0460	homoserine dehydrogenase
F3129_RS15455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3129_RS15460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F3129_RS15465	COG0647	UMP catabolic process
F3129_RS15470	COG2445	Protein of unknown function DUF86
F3129_RS15475	COG4470	Protein conserved in bacteria
F3129_RS15490	COG0739	heme binding
F3129_RS15500	COG0737	Belongs to the 5'-nucleotidase family
F3129_RS15505	COG0730	response to heat
F3129_RS15510	COG1801	Protein of unknown function DUF72
F3129_RS15525	COG2508	Transcriptional regulator
F3129_RS15530	COG0457	Tetratricopeptide repeat
F3129_RS15545	COG2814	Major facilitator Superfamily
F3129_RS15550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F3129_RS15555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3129_RS15560	COG2356	endonuclease I
F3129_RS15565	COG3842	ATPase activity
F3129_RS15570	COG2188	Transcriptional regulator
F3129_RS15575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3129_RS15580	COG0395	ABC-type sugar transport system, permease component
F3129_RS15585	COG1175	transmembrane transport
F3129_RS15590	COG1653	transport
F3129_RS15595	COG2222	sugar isomerase
F3129_RS15600	COG0789	Transcriptional regulator
F3129_RS15625	COG0322	excinuclease ABC activity
F3129_RS15630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3129_RS15635	COG2226	methyltransferase
F3129_RS15650	COG3409	Peptidoglycan-binding domain 1 protein
F3129_RS15655	COG0719	Fe-S assembly protein
F3129_RS15660	COG0822	iron-sulfur transferase activity
F3129_RS15665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3129_RS15670	COG0719	Fe-S assembly protein
F3129_RS15675	COG0396	ATPase activity
F3129_RS15685	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3129_RS15690	COG1464	Belongs to the NlpA lipoprotein family
F3129_RS15695	COG2011	ABC-type metal ion transport system permease component
F3129_RS15700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F3129_RS15710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3129_RS15715	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
F3129_RS15730	COG1393	Belongs to the ArsC family
F3129_RS15735	COG1960	acyl-CoA dehydrogenase activity
F3129_RS15740	COG0183	Belongs to the thiolase family
F3129_RS15745	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3129_RS15745	COG1024	Enoyl-CoA hydratase
F3129_RS15765	COG5577	PFAM Coat F domain
F3129_RS15770	COG1846	Transcriptional regulator
F3129_RS15775	COG0477	Major facilitator Superfamily
F3129_RS15780	COG1942	4-Oxalocrotonate Tautomerase
F3129_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS15790	COG0583	DNA-binding transcription factor activity
F3129_RS15800	COG0583	DNA-binding transcription factor activity
F3129_RS15820	COG1120	ATPase activity
F3129_RS15835	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS15840	COG0783	Belongs to the Dps family
F3129_RS15845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3129_RS15855	COG0745	RESPONSE REGULATOR receiver
F3129_RS15860	COG2770	Histidine kinase
F3129_RS15860	COG2205	protein histidine kinase activity
F3129_RS15870	COG1309	transcriptional regulator
F3129_RS15875	COG0114	fumarate hydratase activity
F3129_RS15885	COG0697	spore germination
F3129_RS15890	COG0814	amino acid
F3129_RS15900	COG2197	response regulator
F3129_RS15905	COG4585	Histidine kinase
F3129_RS15910	COG4758	membrane
F3129_RS15915	COG3595	metallopeptidase activity
F3129_RS15920	COG1842	Phage shock protein A
F3129_RS15925	COG4758	membrane
F3129_RS15930	COG2814	Major facilitator Superfamily
F3129_RS15935	COG2096	Adenosyltransferase
F3129_RS15940	COG1120	ATPase activity
F3129_RS15945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3129_RS15950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3129_RS15955	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS15960	COG3386	PFAM SMP-30 Gluconolaconase
F3129_RS15965	COG2205	protein histidine kinase activity
F3129_RS15970	COG0745	RESPONSE REGULATOR receiver
F3129_RS15980	COG1191	sigma factor activity
F3129_RS15990	COG2140	Oxalate decarboxylase
F3129_RS16000	COG1120	ATPase activity
F3129_RS16005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3129_RS16010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3129_RS16015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3129_RS16020	COG0531	amino acid
F3129_RS16035	COG1988	membrane-bound metal-dependent
F3129_RS16040	COG1368	sulfuric ester hydrolase activity
F3129_RS16045	COG1910	domain protein
F3129_RS16050	COG0725	ABC transporter, periplasmic molybdate-binding protein
F3129_RS16055	COG4149	molybdate abc transporter
F3129_RS16060	COG2197	response regulator
F3129_RS16065	COG3850	Histidine kinase
F3129_RS16070	COG1131	(ABC) transporter
F3129_RS16080	COG0842	Transport permease protein
F3129_RS16085	COG0656	L-ascorbic acid biosynthetic process
F3129_RS16110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F3129_RS16115	COG3973	AAA domain
F3129_RS16120	COG2860	membrane
F3129_RS16130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F3129_RS16135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3129_RS16140	COG2217	Heavy metal translocating P-type atpase
F3129_RS16145	COG2217	Heavy metal translocating P-type atpase
F3129_RS16150	COG2608	mercury ion transmembrane transporter activity
F3129_RS16155	COG1937	Protein conserved in bacteria
F3129_RS16160	COG0673	inositol 2-dehydrogenase activity
F3129_RS16180	COG2814	Major facilitator Superfamily
F3129_RS16195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3129_RS16200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3129_RS16205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3129_RS16210	COG1126	abc transporter atp-binding protein
F3129_RS16215	COG0765	amino acid transport
F3129_RS16220	COG0765	amino acid transport
F3129_RS16225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3129_RS16230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3129_RS16235	COG0454	-acetyltransferase
F3129_RS16240	COG0583	DNA-binding transcription factor activity
F3129_RS16245	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS16265	COG0557	exoribonuclease II activity
F3129_RS16270	COG1647	Serine aminopeptidase, S33
F3129_RS16275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3129_RS16280	COG1476	TRANSCRIPTIONal
F3129_RS16285	COG1396	sequence-specific DNA binding
F3129_RS16290	COG1396	sequence-specific DNA binding
F3129_RS16295	COG1733	regulation of RNA biosynthetic process
F3129_RS16320	COG1131	(ABC) transporter
F3129_RS16325	COG1174	glycine betaine transport
F3129_RS16330	COG1732	Glycine betaine
F3129_RS16335	COG1174	glycine betaine transport
F3129_RS16340	COG0517	IMP dehydrogenase activity
F3129_RS16340	COG1125	glycine betaine transport
F3129_RS16345	COG1510	regulation of RNA biosynthetic process
F3129_RS16350	COG1174	glycine betaine transport
F3129_RS16355	COG1732	Glycine betaine
F3129_RS16360	COG1174	glycine betaine transport
F3129_RS16365	COG1125	glycine betaine transport
F3129_RS16365	COG0517	IMP dehydrogenase activity
F3129_RS16370	COG1510	regulation of RNA biosynthetic process
F3129_RS16375	COG2095	MarC family integral membrane protein
F3129_RS16385	COG3064	Membrane
F3129_RS16390	COG4640	response to antibiotic
F3129_RS16395	COG0456	acetyltransferase
F3129_RS16410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F3129_RS16425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F3129_RS16430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3129_RS16435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F3129_RS16445	COG2234	aminopeptidase activity
F3129_RS16465	COG0126	phosphoglycerate kinase activity
F3129_RS16475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F3129_RS16480	COG2390	Transcriptional regulator
F3129_RS16485	COG2814	Major facilitator Superfamily
F3129_RS16490	COG1609	Transcriptional regulator
F3129_RS16495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3129_RS16505	COG0583	DNA-binding transcription factor activity
F3129_RS16510	COG0697	spore germination
F3129_RS16515	COG1113	amino acid transport
F3129_RS16525	COG1609	Transcriptional regulator
F3129_RS16535	COG0561	phosphatase activity
F3129_RS16540	COG1737	Transcriptional regulator
F3129_RS16545	COG1070	Carbohydrate kinase
F3129_RS16570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3129_RS16575	COG2186	Transcriptional regulator
F3129_RS16580	COG1620	l-lactate permease
F3129_RS16585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F3129_RS16595	COG5039	Polysaccharide pyruvyl transferase
F3129_RS16600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F3129_RS16605	COG0110	maltose O-acetyltransferase activity
F3129_RS16610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3129_RS16615	COG2244	polysaccharide biosynthetic process
F3129_RS16620	COG1216	Glycosyl transferase, family 2
F3129_RS16625	COG5039	Polysaccharide pyruvyl transferase
F3129_RS16630	COG1216	Glycosyl transferase, family 2
F3129_RS16640	COG0438	transferase activity, transferring glycosyl groups
F3129_RS16645	COG1215	transferase activity, transferring glycosyl groups
F3129_RS16650	COG0438	transferase activity, transferring glycosyl groups
F3129_RS16655	COG1086	Polysaccharide biosynthesis protein
F3129_RS16660	COG0489	protein tyrosine kinase activity
F3129_RS16665	COG3944	biosynthesis protein
F3129_RS16670	COG1396	sequence-specific DNA binding
F3129_RS16675	COG2272	Belongs to the type-B carboxylesterase lipase family
F3129_RS16685	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F3129_RS16690	COG2364	Membrane
F3129_RS16695	COG0456	acetyltransferase
F3129_RS16700	COG3479	Phenolic acid decarboxylase
F3129_RS16750	COG2223	nitrite transmembrane transporter activity
F3129_RS16755	COG1609	Transcriptional regulator
F3129_RS16765	COG0583	DNA-binding transcription factor activity
F3129_RS16770	COG2828	Protein conserved in bacteria
F3129_RS16775	COG0477	Major facilitator Superfamily
F3129_RS16775	COG2814	Major facilitator Superfamily
F3129_RS16780	COG1611	Belongs to the LOG family
F3129_RS16785	COG1694	Mazg nucleotide pyrophosphohydrolase
F3129_RS16790	COG0659	secondary active sulfate transmembrane transporter activity
F3129_RS16795	COG0288	reversible hydration of carbon dioxide
F3129_RS16805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3129_RS16810	COG4290	ribonuclease
F3129_RS16825	COG2162	N-hydroxyarylamine O-acetyltransferase activity
F3129_RS16830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3129_RS16840	COG0391	Required for morphogenesis under gluconeogenic growth conditions
F3129_RS16850	COG1051	belongs to the nudix hydrolase family
F3129_RS16855	COG0492	ferredoxin-NADP+ reductase activity
F3129_RS16860	COG3883	PFAM NLP P60 protein
F3129_RS16860	COG0791	NLP P60 protein
F3129_RS16865	COG0457	Tetratricopeptide repeat
F3129_RS16870	COG5002	protein histidine kinase activity
F3129_RS16875	COG0745	RESPONSE REGULATOR receiver
F3129_RS16880	COG1132	(ABC) transporter
F3129_RS16885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F3129_RS16885	COG0140	phosphoribosyl-ATP diphosphatase activity
F3129_RS16910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F3129_RS16925	COG4990	cell redox homeostasis
F3129_RS16930	COG0110	maltose O-acetyltransferase activity
F3129_RS16950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3129_RS16960	COG2188	Transcriptional regulator
F3129_RS16965	COG1309	transcriptional regulator
F3129_RS16970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F3129_RS16980	COG1950	PFAM Membrane protein of
F3129_RS16985	COG1983	PspC domain protein
F3129_RS16990	COG3595	metallopeptidase activity
F3129_RS17005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3129_RS17015	COG4897	Protein conserved in bacteria
F3129_RS17020	COG3848	Pyruvate phosphate dikinase
F3129_RS17020	COG0574	Belongs to the PEP-utilizing enzyme family
F3129_RS17025	COG1309	transcriptional regulator
F3129_RS17030	COG2814	Major facilitator Superfamily
F3129_RS17045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3129_RS17055	COG0793	Belongs to the peptidase S41A family
F3129_RS17055	COG3409	Peptidoglycan-binding domain 1 protein
F3129_RS17060	COG3420	alginic acid biosynthetic process
F3129_RS17065	COG2177	Part of the ABC transporter FtsEX involved in
F3129_RS17070	COG2884	Cell division ATP-binding protein ftsE
F3129_RS17075	COG2010	Cytochrome c
F3129_RS17080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3129_RS17095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3129_RS17110	COG1516	flagellar protein fliS
F3129_RS17115	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F3129_RS17120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3129_RS17140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3129_RS17145	COG4786	Flagellar basal body rod
F3129_RS17145	COG1256	bacterial-type flagellum assembly
F3129_RS17150	COG3418	PFAM FlgN family protein
F3129_RS17155	COG2747	anti-sigma28 factor FlgM
F3129_RS17165	COG1040	competence protein
F3129_RS17175	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
F3129_RS17180	COG1307	EDD domain protein, DegV family
F3129_RS17185	COG2197	response regulator
F3129_RS17190	COG4585	Histidine kinase
F3129_RS17195	COG1739	Uncharacterized protein family UPF0029
F3129_RS17200	COG1316	TRANSCRIPTIONal
F3129_RS17205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F3129_RS17210	COG0438	transferase activity, transferring glycosyl groups
F3129_RS17215	COG1215	transferase activity, transferring glycosyl groups
F3129_RS17220	COG3206	protein involved in exopolysaccharide biosynthesis
F3129_RS17225	COG3307	-O-antigen
F3129_RS17230	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3129_RS17235	COG0297	glycogen (starch) synthase activity
F3129_RS17235	COG0438	transferase activity, transferring glycosyl groups
F3129_RS17240	COG2244	polysaccharide biosynthetic process
F3129_RS17250	COG2247	cell wall binding repeat
F3129_RS17250	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3129_RS17255	COG2247	cell wall binding repeat
F3129_RS17255	COG2385	sporulation resulting in formation of a cellular spore
F3129_RS17265	COG1316	TRANSCRIPTIONal
F3129_RS17270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F3129_RS17275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3129_RS17280	COG1134	teichoic acid transport
F3129_RS17285	COG1682	transport, permease protein
F3129_RS17290	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
F3129_RS17295	COG0438	transferase activity, transferring glycosyl groups
F3129_RS17300	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F3129_RS17305	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
F3129_RS17310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
F3129_RS17315	COG4193	domain, Protein
F3129_RS17320	COG1482	cell wall glycoprotein biosynthetic process
F3129_RS17325	COG0697	spore germination
F3129_RS17330	COG0814	amino acid
F3129_RS17340	COG1215	transferase activity, transferring glycosyl groups
F3129_RS17345	COG2814	Major facilitator Superfamily
F3129_RS17350	COG1316	TRANSCRIPTIONal
F3129_RS17355	COG0561	phosphatase activity
F3129_RS17365	COG0791	NLP P60 protein
F3129_RS17375	COG2843	Capsule synthesis protein
F3129_RS17385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F3129_RS17395	COG0697	spore germination
F3129_RS17400	COG0814	amino acid
F3129_RS17410	COG1609	Transcriptional regulator
F3129_RS17415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3129_RS17425	COG1129	ABC transporter
F3129_RS17430	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3129_RS17435	COG1879	ABC-type sugar transport system periplasmic component
F3129_RS17440	COG3103	Sh3 type 3 domain protein
F3129_RS17445	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3129_RS17450	COG3527	Alpha-acetolactate decarboxylase
F3129_RS17455	COG0028	Belongs to the TPP enzyme family
F3129_RS17460	COG0583	DNA-binding transcription factor activity
F3129_RS17465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F3129_RS17480	COG5337	Spore coat protein CotH
F3129_RS17490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3129_RS17500	COG0405	Gamma-glutamyltransferase
F3129_RS17505	COG1522	sequence-specific DNA binding
F3129_RS17510	COG2059	Chromate
F3129_RS17515	COG2059	Chromate
F3129_RS17555	COG5444	nuclease activity
F3129_RS17570	COG3878	Protein conserved in bacteria
F3129_RS17575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3129_RS17580	COG4464	protein tyrosine phosphatase activity
F3129_RS17585	COG0489	protein tyrosine kinase activity
F3129_RS17590	COG3944	biosynthesis protein
F3129_RS17605	COG4715	Zinc finger, swim domain protein
F3129_RS17610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F3129_RS17615	COG0561	phosphatase activity
F3129_RS17620	COG1349	DNA-binding transcription factor activity
F3129_RS17625	COG0629	single-stranded DNA binding
F3129_RS17650	COG0457	Tetratricopeptide repeat
F3129_RS17655	COG4786	Flagellar basal body rod
F3129_RS17660	COG4786	Flagellar basal body rod
F3129_RS17665	COG1077	Cell shape determining protein MreB Mrl
F3129_RS17670	COG1609	Transcriptional regulator
F3129_RS17675	COG1846	Transcriptional regulator
F3129_RS17680	COG2814	Major facilitator Superfamily
F3129_RS17685	COG1953	Uracil, thiamine, allantoin
F3129_RS17690	COG0477	Major facilitator Superfamily
F3129_RS17695	COG1335	isochorismatase
F3129_RS17700	COG0004	ammonium transporteR
F3129_RS17705	COG0347	Belongs to the P(II) protein family
F3129_RS17710	COG0772	Belongs to the SEDS family
F3129_RS17715	COG0671	phosphoesterase, PA-phosphatase related
F3129_RS17725	COG0739	heme binding
F3129_RS17730	COG1247	-acetyltransferase
F3129_RS17745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3129_RS17760	COG0726	polysaccharide deacetylase
F3129_RS17770	COG1959	2 iron, 2 sulfur cluster binding
F3129_RS17785	COG0831	urea catabolic process
F3129_RS17790	COG3237	CsbD-like
F3129_RS17795	COG1994	Peptidase M50
F3129_RS17800	COG0457	Tetratricopeptide repeat
F3129_RS17810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F3129_RS17815	COG2304	oxidoreductase activity
F3129_RS17820	COG2304	oxidoreductase activity
F3129_RS17830	COG2385	sporulation resulting in formation of a cellular spore
F3129_RS17835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F3129_RS17845	COG4836	Membrane
F3129_RS17915	COG0698	ribose 5-phosphate isomerase
F3129_RS17920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3129_RS17930	COG0009	L-threonylcarbamoyladenylate synthase
F3129_RS17935	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F3129_RS17955	COG2890	protein-(glutamine-N5) methyltransferase activity
F3129_RS17960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F3129_RS17965	COG0346	lactoylglutathione lyase activity
F3129_RS17970	COG0789	Transcriptional regulator
F3129_RS17975	COG0679	Auxin Efflux Carrier
F3129_RS17980	COG0281	malic enzyme
F3129_RS17995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F3129_RS18000	COG1494	fructose-1,6-bisphosphatase
F3129_RS18005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F3129_RS18015	COG0191	fructose-bisphosphate aldolase activity
F3129_RS18020	COG2204	response regulator
F3129_RS18025	COG4821	SIS domain
F3129_RS18040	COG0247	lactate metabolic process
F3129_RS18040	COG2181	nitrate reductase activity
F3129_RS18045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3129_RS18060	COG1132	(ABC) transporter
F3129_RS18065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3129_RS18075	COG2181	nitrate reductase activity
F3129_RS18080	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F3129_RS18085	COG1140	nitrate reductase beta subunit
F3129_RS18090	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F3129_RS18095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3129_RS18105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3129_RS18110	COG2223	nitrite transmembrane transporter activity
F3129_RS18120	COG4506	Protein conserved in bacteria
F3129_RS18130	COG3391	amine dehydrogenase activity
F3129_RS18135	COG3391	amine dehydrogenase activity
F3129_RS18145	COG0457	Tetratricopeptide repeat
F3129_RS18190	COG0010	Belongs to the arginase family
F3129_RS18195	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
F3129_RS18200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3129_RS18215	COG1994	Peptidase M50
F3129_RS18220	COG1942	4-Oxalocrotonate Tautomerase
F3129_RS18225	COG1846	Transcriptional regulator
F3129_RS18235	COG0531	amino acid
F3129_RS18240	COG3465	dGTPase activity
F3129_RS18245	COG1078	dGTPase activity
F3129_RS18260	COG1695	Transcriptional regulator
F3129_RS18270	COG1131	(ABC) transporter
F3129_RS18275	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
F3129_RS18305	COG0583	DNA-binding transcription factor activity
F3129_RS18310	COG2855	membrane
F3129_RS18315	COG0280	phosphate acetyltransferase
F3129_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS18330	COG0436	Aminotransferase
F3129_RS18360	COG2814	Major facilitator Superfamily
F3129_RS18365	COG2814	Major facilitator Superfamily
F3129_RS18370	COG0833	amino acid
F3129_RS18375	COG4187	Peptidase family M20/M25/M40
F3129_RS18380	COG1012	belongs to the aldehyde dehydrogenase family
F3129_RS18385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3129_RS18390	COG2205	protein histidine kinase activity
F3129_RS18395	COG0745	RESPONSE REGULATOR receiver
F3129_RS18410	COG1131	(ABC) transporter
F3129_RS18415	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
F3129_RS18420	COG1091	dTDP-4-dehydrorhamnose reductase activity
F3129_RS18425	COG1088	dTDP-glucose 4,6-dehydratase activity
F3129_RS18430	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F3129_RS18435	COG3980	spore coat polysaccharide biosynthesis protein
F3129_RS18440	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
F3129_RS18445	COG2089	acid synthase
F3129_RS18450	COG0456	acetyltransferase
F3129_RS18455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F3129_RS18460	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
F3129_RS18465	COG0463	Glycosyl transferase, family 2
F3129_RS18475	COG2363	Small membrane protein
F3129_RS18480	COG2233	PERMEase
F3129_RS18495	COG1216	Glycosyl transferase, family 2
F3129_RS18510	COG1695	Transcriptional regulator
F3129_RS18515	COG0351	phosphomethylpyrimidine kinase
F3129_RS18525	COG1621	beta-fructofuranosidase activity
F3129_RS18530	COG1263	PTS System
F3129_RS18530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3129_RS18535	COG3711	transcriptional antiterminator
F3129_RS18545	COG1404	Belongs to the peptidase S8 family
F3129_RS18550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3129_RS18555	COG0778	Nitroreductase
F3129_RS18560	COG0772	Belongs to the SEDS family
F3129_RS18565	COG0454	-acetyltransferase
F3129_RS18585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3129_RS18590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3129_RS18595	COG2261	transglycosylase associated protein
F3129_RS18600	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
F3129_RS18605	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
F3129_RS18610	COG2246	polysaccharide biosynthetic process
F3129_RS18615	COG1309	transcriptional regulator
F3129_RS18635	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F3129_RS18640	COG2837	iron assimilation
F3129_RS18645	COG2822	iron ion transport
F3129_RS18660	COG0583	DNA-binding transcription factor activity
F3129_RS18670	COG1346	cytolysis
F3129_RS18675	COG4895	conserved protein (DUF2196)
F3129_RS18680	COG0789	Transcriptional regulator
F3129_RS18685	COG5504	Zn-dependent protease
F3129_RS18690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F3129_RS18695	COG0346	lactoylglutathione lyase activity
F3129_RS18700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3129_RS18705	COG1404	Belongs to the peptidase S8 family
F3129_RS18710	COG1442	glycosyl transferase family 8
F3129_RS18715	COG2357	RelA SpoT domain protein
F3129_RS18720	COG1575	Belongs to the MenA family. Type 1 subfamily
F3129_RS18745	COG1696	Membrane protein involved in D-alanine export
F3129_RS18755	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
F3129_RS18760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3129_RS18765	COG1486	melibiose metabolic process
F3129_RS18770	COG1447	Phosphotransferase system cellobiose-specific component IIA
F3129_RS18775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3129_RS18780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3129_RS18785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3129_RS18785	COG3711	transcriptional antiterminator
F3129_RS18800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3129_RS18805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3129_RS18815	COG0640	Transcriptional regulator
F3129_RS18820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F3129_RS18825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3129_RS18830	COG1447	Phosphotransferase system cellobiose-specific component IIA
F3129_RS18835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3129_RS18840	COG2723	6-phospho-beta-galactosidase activity
F3129_RS18845	COG1940	carbohydrate kinase activity
F3129_RS18850	COG1482	cell wall glycoprotein biosynthetic process
F3129_RS18860	COG0753	catalase activity
F3129_RS18865	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
F3129_RS18870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F3129_RS18875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F3129_RS18880	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F3129_RS18885	COG4988	ABC transporter
F3129_RS18890	COG1294	oxidase, subunit
F3129_RS18895	COG1271	oxidase subunit
F3129_RS18900	COG3493	citrate carrier protein
F3129_RS18905	COG0726	polysaccharide deacetylase
F3129_RS18910	COG3842	ATPase activity
F3129_RS18915	COG2508	Transcriptional regulator
F3129_RS18920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3129_RS18930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3129_RS18940	COG4894	glucomannan catabolic process
F3129_RS18945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F3129_RS18950	COG0500	methyltransferase
F3129_RS18955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3129_RS18970	COG0753	catalase activity
F3129_RS18970	COG0693	protein deglycase activity
F3129_RS18975	COG2851	Citrate transporter
F3129_RS18980	COG2273	Hydrolase Family 16
F3129_RS18985	COG3711	transcriptional antiterminator
F3129_RS18990	COG2270	Major facilitator Superfamily
F3129_RS18995	COG0513	Belongs to the DEAD box helicase family
F3129_RS19085	COG0697	spore germination
F3129_RS19090	COG0589	response to stress
F3129_RS19095	COG2723	6-phospho-beta-galactosidase activity
F3129_RS19100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3129_RS19100	COG2190	(PTS) system
F3129_RS19100	COG1263	PTS System
F3129_RS19110	COG0494	nUDIX hydrolase
F3129_RS19115	COG3507	Belongs to the glycosyl hydrolase 43 family
F3129_RS19140	COG0010	Belongs to the arginase family
F3129_RS19145	COG0833	amino acid
F3129_RS19150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F3129_RS19155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3129_RS19165	COG2390	Transcriptional regulator
F3129_RS19170	COG0561	phosphatase activity
F3129_RS19200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3129_RS19205	COG5294	Protein conserved in bacteria
F3129_RS19210	COG0577	efflux transmembrane transporter activity
F3129_RS19215	COG1136	(ABC) transporter
F3129_RS19220	COG2205	protein histidine kinase activity
F3129_RS19225	COG0745	RESPONSE REGULATOR receiver
F3129_RS19240	COG1082	Xylose isomerase domain protein TIM barrel
F3129_RS19250	COG2814	Major facilitator Superfamily
F3129_RS19280	COG1349	DNA-binding transcription factor activity
F3129_RS19285	COG0667	Aldo Keto reductase
F3129_RS19290	COG2814	Major facilitator Superfamily
F3129_RS19305	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS19310	COG2197	response regulator
F3129_RS19315	COG4585	Histidine kinase
F3129_RS19320	COG3239	Fatty acid desaturase
F3129_RS19330	COG1309	transcriptional regulator
F3129_RS19335	COG1012	belongs to the aldehyde dehydrogenase family
F3129_RS19340	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3129_RS19350	COG0640	Transcriptional regulator
F3129_RS19355	COG2814	Major facilitator Superfamily
F3129_RS19360	COG1714	RDD family
F3129_RS19370	COG0450	alkyl hydroperoxide reductase
F3129_RS19375	COG3634	alkyl hydroperoxide reductase activity
F3129_RS19380	COG3177	Filamentation induced by cAMP protein fic
F3129_RS19385	COG1113	amino acid transport
F3129_RS19395	COG2080	2 iron, 2 sulfur cluster binding
F3129_RS19410	COG2068	MobA-Related Protein
F3129_RS19415	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F3129_RS19455	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F3129_RS19460	COG0667	Aldo Keto reductase
F3129_RS19465	COG0456	acetyltransferase
F3129_RS19470	COG0457	Tetratricopeptide repeat
F3129_RS19475	COG0010	Belongs to the arginase family
F3129_RS19480	COG0833	amino acid
F3129_RS19485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3129_RS19490	COG5658	integral membrane protein
F3129_RS19495	COG0640	Transcriptional regulator
F3129_RS19500	COG3829	transcription factor binding
F3129_RS19510	COG0488	(ABC) transporter
F3129_RS19525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3129_RS19530	COG3850	Histidine kinase
F3129_RS19530	COG5002	protein histidine kinase activity
F3129_RS19535	COG0745	RESPONSE REGULATOR receiver
F3129_RS19540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3129_RS19545	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F3129_RS19550	COG4853	Protein conserved in bacteria
F3129_RS19555	COG4863	YycH protein
F3129_RS19560	COG5002	protein histidine kinase activity
F3129_RS19565	COG0745	RESPONSE REGULATOR receiver
F3129_RS19600	COG0346	lactoylglutathione lyase activity
F3129_RS19605	COG0305	Participates in initiation and elongation during chromosome replication
F3129_RS19630	COG3093	addiction module antidote protein HigA
F3129_RS19635	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3129_RS19650	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
F3129_RS19655	COG0438	transferase activity, transferring glycosyl groups
F3129_RS19675	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
F3129_RS19680	COG4241	membrane
F3129_RS19690	COG5577	PFAM Coat F domain
F3129_RS19695	COG1733	regulation of RNA biosynthetic process
F3129_RS19705	COG0697	spore germination
F3129_RS19710	COG1621	beta-fructofuranosidase activity
F3129_RS19715	COG1621	beta-fructofuranosidase activity
F3129_RS19720	COG1802	Transcriptional regulator
F3129_RS19725	COG2318	DinB family
F3129_RS19730	COG2211	Major facilitator Superfamily
F3129_RS19735	COG0583	DNA-binding transcription factor activity
F3129_RS19745	COG2814	Major facilitator Superfamily
F3129_RS19750	COG0583	DNA-binding transcription factor activity
F3129_RS19760	COG0778	Nitroreductase
F3129_RS19765	COG1846	Transcriptional regulator
F3129_RS19770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3129_RS19775	COG1846	Transcriptional regulator
F3129_RS19780	COG2153	protein acetylation
F3129_RS19790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3129_RS19795	COG0583	DNA-binding transcription factor activity
F3129_RS19800	COG1028	Short-chain dehydrogenase reductase Sdr
F3129_RS19820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3129_RS19825	COG0697	spore germination
F3129_RS19830	COG1331	Highly conserved protein containing a thioredoxin domain
F3129_RS19835	COG1266	CAAX protease self-immunity
F3129_RS19840	COG2814	Major facilitator Superfamily
F3129_RS19840	COG0477	Major facilitator Superfamily
F3129_RS19845	COG0346	lactoylglutathione lyase activity
F3129_RS19850	COG1609	Transcriptional regulator
F3129_RS19855	COG0708	Exodeoxyribonuclease III
F3129_RS19860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3129_RS19865	COG2169	Transcriptional regulator
F3129_RS19875	COG0629	single-stranded DNA binding
F3129_RS19885	COG0012	GTP binding
F3129_RS19890	COG0243	molybdopterin cofactor binding
F3129_RS19895	COG4481	Protein conserved in bacteria
F3129_RS19900	COG3949	Membrane
F3129_RS19915	COG1475	DNA binding
F3129_RS19920	COG1192	Involved in chromosome partitioning
F3129_RS19945	COG1847	R3H domain protein
F3129_RS19950	COG0706	membrane insertase activity