locus-tag	class	description
PAN99_RS00010	COG0592	DNA-directed DNA polymerase activity
PAN99_RS00015	COG2501	S4 domain
PAN99_RS00030	COG0187	DNA topoisomerase II activity
PAN99_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAN99_RS00070	COG0516	GMP reductase activity
PAN99_RS00070	COG0517	IMP dehydrogenase activity
PAN99_RS00075	COG1686	Belongs to the peptidase S11 family
PAN99_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
PAN99_RS00105	COG1428	Deoxynucleoside kinase
PAN99_RS00110	COG1428	Deoxynucleoside kinase
PAN99_RS00115	COG1388	LysM domain
PAN99_RS00115	COG3858	chitin binding
PAN99_RS00120	COG1335	isochorismatase
PAN99_RS00125	COG0590	tRNA wobble adenosine to inosine editing
PAN99_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAN99_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PAN99_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
PAN99_RS00195	COG3853	Toxic anion resistance protein (TelA)
PAN99_RS00200	COG1982	Orn Lys Arg decarboxylase major
PAN99_RS00210	COG3870	Protein conserved in bacteria
PAN99_RS00215	COG1728	Protein conserved in bacteria
PAN99_RS00220	COG0470	DNA polymerase III
PAN99_RS00225	COG1774	PSP1 C-terminal conserved region
PAN99_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PAN99_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PAN99_RS00250	COG2002	toxin-antitoxin pair type II binding
PAN99_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAN99_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAN99_RS00260	COG0084	hydrolase, TatD family'
PAN99_RS00265	COG3583	domain protein
PAN99_RS00265	COG3584	3D domain protein
PAN99_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PAN99_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PAN99_RS00285	COG4466	Protein conserved in bacteria
PAN99_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PAN99_RS00305	COG0251	oxidation-reduction process
PAN99_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PAN99_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PAN99_RS00345	COG2002	toxin-antitoxin pair type II binding
PAN99_RS00350	COG2244	polysaccharide biosynthetic process
PAN99_RS00355	COG3956	TIGRFAM MazG family protein
PAN99_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PAN99_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PAN99_RS00380	COG1098	S1 RNA binding domain
PAN99_RS00395	COG2208	phosphoserine phosphatase activity
PAN99_RS00400	COG2304	oxidoreductase activity
PAN99_RS00405	COG0515	serine threonine protein kinase
PAN99_RS00410	COG0037	tRNA processing
PAN99_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PAN99_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PAN99_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PAN99_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PAN99_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PAN99_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
PAN99_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PAN99_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PAN99_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PAN99_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PAN99_RS00475	COG1396	sequence-specific DNA binding
PAN99_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAN99_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PAN99_RS00565	COG4463	regulation of RNA biosynthetic process
PAN99_RS00570	COG3880	PFAM UvrB UvrC protein
PAN99_RS00580	COG0542	response to heat
PAN99_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PAN99_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PAN99_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
PAN99_RS00615	COG1045	serine acetyltransferase
PAN99_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PAN99_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAN99_RS00635	COG3688	RNA-binding protein containing a PIN domain
PAN99_RS00640	COG1595	DNA-templated transcription, initiation
PAN99_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PAN99_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
PAN99_RS00680	COG2813	Specifically methylates the guanine in position
PAN99_RS00695	COG1358	cellular component organization or biogenesis
PAN99_RS00720	COG0596	Alpha beta hydrolase
PAN99_RS00830	COG0201	protein transport
PAN99_RS00840	COG0024	Methionine aminopeptidase
PAN99_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PAN99_RS00880	COG1122	ATPase activity
PAN99_RS00885	COG1122	ATPase activity
PAN99_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAN99_RS00910	COG2226	methyltransferase
PAN99_RS00915	COG2318	DinB family
PAN99_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
PAN99_RS00930	COG0489	protein tyrosine kinase activity
PAN99_RS00940	COG2194	sulfuric ester hydrolase activity
PAN99_RS00945	COG0726	polysaccharide deacetylase
PAN99_RS01005	COG0738	Major facilitator superfamily
PAN99_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAN99_RS01020	COG1063	alcohol dehydrogenase
PAN99_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
PAN99_RS01030	COG0385	Bile acid
PAN99_RS01035	COG2819	hydrolase of the alpha beta superfamily
PAN99_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAN99_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAN99_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PAN99_RS01055	COG2207	Transcriptional regulator
PAN99_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PAN99_RS01060	COG3876	Protein conserved in bacteria
PAN99_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
PAN99_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PAN99_RS01075	COG1263	PTS System
PAN99_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PAN99_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PAN99_RS01090	COG1683	Conserved Protein
PAN99_RS01120	COG1595	DNA-templated transcription, initiation
PAN99_RS01125	COG5662	AntiSigma factor
PAN99_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PAN99_RS01135	COG4856	YbbR-like protein
PAN99_RS01175	COG1346	cytolysis
PAN99_RS01180	COG1380	Effector of murein hydrolase LrgA
PAN99_RS01185	COG1846	Transcriptional regulator
PAN99_RS01190	COG1113	amino acid transport
PAN99_RS01195	COG1011	Hydrolase
PAN99_RS01200	COG4585	Histidine kinase
PAN99_RS01205	COG2197	response regulator
PAN99_RS01210	COG1131	(ABC) transporter
PAN99_RS01250	COG0531	amino acid
PAN99_RS01255	COG0584	glycerophosphoryl diester phosphodiesterase
PAN99_RS01260	COG2271	Major facilitator Superfamily
PAN99_RS01270	COG2368	4-hydroxyphenylacetate
PAN99_RS01280	COG3409	Peptidoglycan-binding domain 1 protein
PAN99_RS01295	COG0371	Dehydrogenase
PAN99_RS01305	COG1183	phosphatidylcholine synthase activity
PAN99_RS01310	COG0586	Pfam SNARE associated Golgi protein
PAN99_RS01315	COG0688	phosphatidylethanolamine metabolic process
PAN99_RS01330	COG1301	dicarboxylic acid transport
PAN99_RS01335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PAN99_RS01340	COG0833	amino acid
PAN99_RS01345	COG2040	homocysteine
PAN99_RS01350	COG1115	amino acid carrier protein
PAN99_RS01355	COG2066	Belongs to the glutaminase family
PAN99_RS01360	COG4191	Histidine kinase
PAN99_RS01365	COG0784	Response regulator, receiver
PAN99_RS01370	COG3173	Aminoglycoside phosphotransferase
PAN99_RS01380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAN99_RS01385	COG0778	Nitroreductase
PAN99_RS01390	COG0346	lactoylglutathione lyase activity
PAN99_RS01395	COG2259	Doxx family
PAN99_RS01400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PAN99_RS01415	COG3773	Cell wall hydrolase
PAN99_RS01420	COG3540	Alkaline phosphatase
PAN99_RS01425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PAN99_RS01430	COG0805	protein transport
PAN99_RS01440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PAN99_RS01445	COG0477	Major facilitator Superfamily
PAN99_RS01450	COG1309	transcriptional regulator
PAN99_RS01455	COG0252	asparaginase activity
PAN99_RS01460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PAN99_RS01465	COG1405	negative regulation of cell septum assembly
PAN99_RS01465	COG3012	SEC-C Motif Domain Protein
PAN99_RS01470	COG0667	Aldo Keto reductase
PAN99_RS01480	COG1595	DNA-templated transcription, initiation
PAN99_RS01485	COG1595	DNA-templated transcription, initiation
PAN99_RS01490	COG1876	peptidase activity
PAN99_RS01495	COG0457	Tetratricopeptide repeat
PAN99_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS01505	COG0366	Alpha amylase catalytic
PAN99_RS01510	COG0803	Belongs to the bacterial solute-binding protein 9 family
PAN99_RS01515	COG1121	(ABC) transporter
PAN99_RS01520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PAN99_RS01525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAN99_RS01530	COG2310	stress, protein
PAN99_RS01535	COG2310	stress, protein
PAN99_RS01540	COG2310	stress, protein
PAN99_RS01545	COG0861	Integral membrane protein TerC family
PAN99_RS01555	COG3853	Toxic anion resistance protein (TelA)
PAN99_RS01560	COG0477	Major facilitator Superfamily
PAN99_RS01565	COG4175	Glycine betaine
PAN99_RS01565	COG0517	IMP dehydrogenase activity
PAN99_RS01570	COG4176	ABC-type proline glycine betaine transport system permease component
PAN99_RS01575	COG2113	Glycine betaine
PAN99_RS01580	COG1473	amidohydrolase
PAN99_RS01585	COG1288	antiporter activity
PAN99_RS01600	COG0366	Alpha amylase catalytic
PAN99_RS01610	COG2814	Major facilitator Superfamily
PAN99_RS01615	COG1846	Transcriptional regulator
PAN99_RS01620	COG1280	lysine exporter protein (LysE YggA)
PAN99_RS01625	COG3403	YqcI/YcgG family
PAN99_RS01630	COG1113	amino acid transport
PAN99_RS01635	COG3665	Urea carboxylase-associated protein
PAN99_RS01650	COG1660	Displays ATPase and GTPase activities
PAN99_RS01660	COG2271	Major facilitator Superfamily
PAN99_RS01665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PAN99_RS01670	COG3458	cephalosporin-C deacetylase activity
PAN99_RS01675	COG3541	Predicted nucleotidyltransferase
PAN99_RS01680	COG0506	proline dehydrogenase activity
PAN99_RS01685	COG1012	belongs to the aldehyde dehydrogenase family
PAN99_RS01690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAN99_RS01695	COG2508	Transcriptional regulator
PAN99_RS01705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PAN99_RS01705	COG1587	Uroporphyrinogen-III synthase
PAN99_RS01710	COG2146	nitrite reductase [NAD(P)H] activity
PAN99_RS01715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PAN99_RS01725	COG0523	cobalamin synthesis protein
PAN99_RS01730	COG1063	alcohol dehydrogenase
PAN99_RS01735	COG1714	RDD family
PAN99_RS01745	COG2723	6-phospho-beta-galactosidase activity
PAN99_RS01760	COG3209	COG3209 Rhs family protein
PAN99_RS01765	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PAN99_RS01770	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
PAN99_RS01775	COG1733	regulation of RNA biosynthetic process
PAN99_RS01780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS01805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
PAN99_RS01820	COG2364	Membrane
PAN99_RS01825	COG1126	abc transporter atp-binding protein
PAN99_RS01830	COG0765	amino acid transport
PAN99_RS01835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAN99_RS01840	COG0583	DNA-binding transcription factor activity
PAN99_RS01845	COG0163	prenyltransferase activity
PAN99_RS01850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PAN99_RS01865	COG3104	oligopeptide transport
PAN99_RS01870	COG5434	Belongs to the glycosyl hydrolase 28 family
PAN99_RS01880	COG0697	spore germination
PAN99_RS01890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PAN99_RS01895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAN99_RS01900	COG0456	acetyltransferase
PAN99_RS01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAN99_RS01910	COG0765	amino acid transport
PAN99_RS01915	COG1126	abc transporter atp-binding protein
PAN99_RS01920	COG1473	amidohydrolase
PAN99_RS01925	COG2079	MmgE PrpD family protein
PAN99_RS01930	COG1136	(ABC) transporter
PAN99_RS01935	COG0577	efflux transmembrane transporter activity
PAN99_RS01940	COG0745	RESPONSE REGULATOR receiver
PAN99_RS01945	COG5002	protein histidine kinase activity
PAN99_RS01945	COG3850	Histidine kinase
PAN99_RS01950	COG0457	Tetratricopeptide repeat
PAN99_RS01965	COG0527	aspartate kinase activity
PAN99_RS01970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAN99_RS01975	COG4605	iron ion homeostasis
PAN99_RS01980	COG4604	ABC transporter, ATP-binding protein
PAN99_RS01985	COG4607	ABC-type enterochelin transport system periplasmic component
PAN99_RS01990	COG2814	Major facilitator Superfamily
PAN99_RS01995	COG1309	transcriptional regulator
PAN99_RS02000	COG0778	Nitroreductase
PAN99_RS02005	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PAN99_RS02010	COG0640	Transcriptional regulator
PAN99_RS02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PAN99_RS02020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAN99_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
PAN99_RS02030	COG4975	Glucose uptake
PAN99_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS02040	COG4549	nuclear export factor GLE1
PAN99_RS02045	COG1276	copper resistance
PAN99_RS02045	COG2372	response to copper ion
PAN99_RS02050	COG1349	DNA-binding transcription factor activity
PAN99_RS02060	COG2213	PTS system mannitol-specific
PAN99_RS02065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PAN99_RS02075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PAN99_RS02085	COG0561	phosphatase activity
PAN99_RS02095	COG1914	H( )-stimulated, divalent metal cation uptake system
PAN99_RS02105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PAN99_RS02110	COG1984	allophanate hydrolase subunit 2
PAN99_RS02115	COG1414	Transcriptional regulator
PAN99_RS02120	COG2755	lipolytic protein G-D-S-L family
PAN99_RS02130	COG2329	Antibiotic biosynthesis monooxygenase
PAN99_RS02135	COG0768	penicillin binding
PAN99_RS02140	COG4989	oxidoreductase activity
PAN99_RS02145	COG3711	transcriptional antiterminator
PAN99_RS02150	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS02160	COG1917	Cupin 2, conserved barrel domain protein
PAN99_RS02165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PAN99_RS02170	COG3871	stress protein (general stress protein 26)
PAN99_RS02180	COG2814	Major facilitator Superfamily
PAN99_RS02185	COG1522	sequence-specific DNA binding
PAN99_RS02190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PAN99_RS02190	COG0551	DNA topoisomerase type I activity
PAN99_RS02195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PAN99_RS02200	COG3706	GGDEF domain
PAN99_RS02205	COG5298	Protein conserved in bacteria
PAN99_RS02210	COG1215	transferase activity, transferring glycosyl groups
PAN99_RS02220	COG0531	amino acid
PAN99_RS02225	COG0494	nUDIX hydrolase
PAN99_RS02230	COG0028	Belongs to the TPP enzyme family
PAN99_RS02285	COG0457	Tetratricopeptide repeat
PAN99_RS02315	COG1914	H( )-stimulated, divalent metal cation uptake system
PAN99_RS02335	COG2076	Multidrug Resistance protein
PAN99_RS02340	COG2217	Heavy metal translocating P-type atpase
PAN99_RS02345	COG3729	General stress protein
PAN99_RS02350	COG0662	Cupin 2, conserved barrel domain protein
PAN99_RS02355	COG2329	Antibiotic biosynthesis monooxygenase
PAN99_RS02360	COG3546	catalase activity
PAN99_RS02365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PAN99_RS02370	COG3290	protein histidine kinase activity
PAN99_RS02375	COG4565	transcriptional regulatory protein
PAN99_RS02380	COG1301	dicarboxylic acid transport
PAN99_RS02385	COG0628	permease
PAN99_RS02390	COG1131	(ABC) transporter
PAN99_RS02395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PAN99_RS02405	COG1960	acyl-CoA dehydrogenase activity
PAN99_RS02420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAN99_RS02425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PAN99_RS02435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PAN99_RS02440	COG0513	Belongs to the DEAD box helicase family
PAN99_RS02445	COG3402	PFAM membrane-flanked domain
PAN99_RS02450	COG3428	Bacterial PH domain
PAN99_RS02455	COG0705	Rhomboid family
PAN99_RS02465	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PAN99_RS02470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PAN99_RS02475	COG0864	Transcriptional regulator
PAN99_RS02480	COG2337	Toxic component of a toxin-antitoxin (TA) module
PAN99_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
PAN99_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
PAN99_RS02495	COG2172	sigma factor antagonist activity
PAN99_RS02500	COG2208	phosphoserine phosphatase activity
PAN99_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
PAN99_RS02515	COG1191	sigma factor activity
PAN99_RS02520	COG2208	phosphoserine phosphatase activity
PAN99_RS02525	COG2183	response to ionizing radiation
PAN99_RS02575	COG2249	NAD(P)H dehydrogenase (quinone) activity
PAN99_RS02590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PAN99_RS02595	COG0477	Major facilitator Superfamily
PAN99_RS02605	COG1764	response to oxidative stress
PAN99_RS02610	COG1846	Transcriptional regulator
PAN99_RS02620	COG1959	2 iron, 2 sulfur cluster binding
PAN99_RS02625	COG2910	NAD(P)H-binding
PAN99_RS02630	COG1278	Cold shock
PAN99_RS02640	COG1937	Protein conserved in bacteria
PAN99_RS02645	COG2210	Belongs to the sulfur carrier protein TusA family
PAN99_RS02655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PAN99_RS02655	COG0425	Belongs to the sulfur carrier protein TusA family
PAN99_RS02665	COG0425	Belongs to the sulfur carrier protein TusA family
PAN99_RS02670	COG0730	response to heat
PAN99_RS02675	COG1794	racemase activity, acting on amino acids and derivatives
PAN99_RS02690	COG3621	Patatin-like phospholipase
PAN99_RS02700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PAN99_RS02705	COG1802	Transcriptional regulator
PAN99_RS02710	COG0251	oxidation-reduction process
PAN99_RS02715	COG0814	amino acid
PAN99_RS02720	COG1473	amidohydrolase
PAN99_RS02725	COG2207	Transcriptional regulator
PAN99_RS02725	COG1917	Cupin 2, conserved barrel domain protein
PAN99_RS02735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PAN99_RS02740	COG0477	Major facilitator Superfamily
PAN99_RS02760	COG0277	FAD linked oxidase domain protein
PAN99_RS02785	COG0662	Cupin 2, conserved barrel domain protein
PAN99_RS02800	COG1064	alcohol dehydrogenase
PAN99_RS02805	COG0789	Transcriptional regulator
PAN99_RS02815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PAN99_RS02830	COG2814	Major facilitator Superfamily
PAN99_RS02835	COG1309	transcriptional regulator
PAN99_RS02840	COG5577	PFAM Coat F domain
PAN99_RS02850	COG1063	alcohol dehydrogenase
PAN99_RS02855	COG5577	PFAM Coat F domain
PAN99_RS02865	COG4585	Histidine kinase
PAN99_RS02870	COG2197	response regulator
PAN99_RS02875	COG2409	Drug exporters of the RND superfamily
PAN99_RS02880	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PAN99_RS02885	COG0488	(ABC) transporter
PAN99_RS02890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PAN99_RS02895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAN99_RS02905	COG2814	Major facilitator Superfamily
PAN99_RS02910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PAN99_RS02920	COG0730	response to heat
PAN99_RS02925	COG0456	acetyltransferase
PAN99_RS02930	COG4978	Transcriptional regulator
PAN99_RS02930	COG0789	Transcriptional regulator
PAN99_RS02935	COG0697	spore germination
PAN99_RS02940	COG1051	belongs to the nudix hydrolase family
PAN99_RS02945	COG2226	methyltransferase
PAN99_RS02950	COG0473	3-isopropylmalate dehydrogenase activity
PAN99_RS02955	COG1802	Transcriptional regulator
PAN99_RS02960	COG1819	glycosyl
PAN99_RS02975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PAN99_RS02985	COG1388	LysM domain
PAN99_RS02990	COG2814	Major facilitator Superfamily
PAN99_RS02995	COG2188	Transcriptional regulator
PAN99_RS03000	COG2186	Transcriptional regulator
PAN99_RS03005	COG2807	transmembrane transport
PAN99_RS03010	COG2076	Multidrug Resistance protein
PAN99_RS03015	COG2076	Multidrug Resistance protein
PAN99_RS03020	COG1309	transcriptional regulator
PAN99_RS03025	COG0531	amino acid
PAN99_RS03035	COG3832	glyoxalase III activity
PAN99_RS03040	COG0604	alcohol dehydrogenase
PAN99_RS03045	COG2814	Major facilitator Superfamily
PAN99_RS03085	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PAN99_RS03090	COG0802	atpase or kinase
PAN99_RS03095	COG1214	PFAM Peptidase M22, glycoprotease
PAN99_RS03100	COG0456	acetyltransferase
PAN99_RS03105	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PAN99_RS03110	COG0488	(ABC) transporter
PAN99_RS03125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PAN99_RS03130	COG0805	protein transport
PAN99_RS03140	COG1266	CAAX protease self-immunity
PAN99_RS03200	COG1131	(ABC) transporter
PAN99_RS03205	COG0842	Transport permease protein
PAN99_RS03210	COG0457	Tetratricopeptide repeat
PAN99_RS03215	COG1063	alcohol dehydrogenase
PAN99_RS03220	COG2211	Major facilitator Superfamily
PAN99_RS03225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAN99_RS03235	COG1842	Phage shock protein A
PAN99_RS03240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PAN99_RS03245	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PAN99_RS03250	COG4260	virion core protein, lumpy skin disease virus
PAN99_RS03255	COG2755	lipolytic protein G-D-S-L family
PAN99_RS03255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PAN99_RS03265	COG1595	DNA-templated transcription, initiation
PAN99_RS03270	COG1063	alcohol dehydrogenase
PAN99_RS03275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PAN99_RS03280	COG0823	Involved in the tonB-independent uptake of proteins
PAN99_RS03295	COG2132	Multicopper oxidase
PAN99_RS03300	COG1113	amino acid transport
PAN99_RS03305	COG0714	Associated with various cellular activities
PAN99_RS03310	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
PAN99_RS03315	COG1305	Transglutaminase-like
PAN99_RS03340	COG2252	PERMEase
PAN99_RS03345	COG3064	Membrane
PAN99_RS03365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PAN99_RS03370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PAN99_RS03375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PAN99_RS03380	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PAN99_RS03385	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAN99_RS03400	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PAN99_RS03410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PAN99_RS03415	COG0138	bifunctional purine biosynthesis protein purh
PAN99_RS03420	COG0151	Belongs to the GarS family
PAN99_RS03430	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PAN99_RS03435	COG1470	cell adhesion involved in biofilm formation
PAN99_RS03440	COG4496	protein, YerC YecD
PAN99_RS03445	COG0069	glutamate synthase activity
PAN99_RS03455	COG0210	DNA helicase
PAN99_RS03465	COG4851	CamS sex pheromone cAM373 precursor
PAN99_RS03470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PAN99_RS03475	COG1285	pathogenesis
PAN99_RS03480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAN99_RS03500	COG1309	transcriptional regulator
PAN99_RS03505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAN99_RS03510	COG1597	lipid kinase activity
PAN99_RS03515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAN99_RS03525	COG1131	(ABC) transporter
PAN99_RS03565	COG5444	nuclease activity
PAN99_RS03595	COG3546	catalase activity
PAN99_RS03600	COG0454	-acetyltransferase
PAN99_RS03610	COG2323	membrane
PAN99_RS03615	COG2329	Antibiotic biosynthesis monooxygenase
PAN99_RS03625	COG1366	Belongs to the anti-sigma-factor antagonist family
PAN99_RS03630	COG5583	Uncharacterized small protein (DUF2292)
PAN99_RS03635	COG0196	riboflavin kinase activity
PAN99_RS03640	COG0670	Belongs to the BI1 family
PAN99_RS03650	COG1846	Transcriptional regulator
PAN99_RS03655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PAN99_RS03665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PAN99_RS03665	COG2124	cytochrome p450
PAN99_RS03680	COG1131	(ABC) transporter
PAN99_RS03725	COG4106	trans-aconitate 2-methyltransferase activity
PAN99_RS03730	COG1368	sulfuric ester hydrolase activity
PAN99_RS03735	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PAN99_RS03740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAN99_RS03745	COG1442	glycosyl transferase family 8
PAN99_RS03750	COG1216	Glycosyl transferase, family 2
PAN99_RS03755	COG1442	glycosyl transferase family 8
PAN99_RS03760	COG2223	nitrite transmembrane transporter activity
PAN99_RS03765	COG0531	amino acid
PAN99_RS03770	COG1012	belongs to the aldehyde dehydrogenase family
PAN99_RS03775	COG0840	transmembrane signaling receptor activity
PAN99_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS03785	COG0463	Glycosyl transferase, family 2
PAN99_RS03785	COG0457	Tetratricopeptide repeat
PAN99_RS03790	COG0488	(ABC) transporter
PAN99_RS03795	COG0789	Transcriptional regulator
PAN99_RS03800	COG2814	Major facilitator Superfamily
PAN99_RS03805	COG0488	(ABC) transporter
PAN99_RS03810	COG0513	Belongs to the DEAD box helicase family
PAN99_RS03820	COG2130	NADP-dependent
PAN99_RS03835	COG3866	Pectate lyase
PAN99_RS03840	COG0471	metal ion transport
PAN99_RS03875	COG0745	RESPONSE REGULATOR receiver
PAN99_RS03875	COG2972	Histidine kinase
PAN99_RS03885	COG3279	Response regulator of the LytR AlgR family
PAN99_RS03895	COG3764	Sortase (surface protein transpeptidase)
PAN99_RS03900	COG3290	protein histidine kinase activity
PAN99_RS03905	COG4565	transcriptional regulatory protein
PAN99_RS03910	COG3181	Tripartite tricarboxylate transporter family receptor
PAN99_RS03915	COG2851	Citrate transporter
PAN99_RS03920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAN99_RS03925	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PAN99_RS03935	COG2258	MOSC domain
PAN99_RS03955	COG0024	Methionine aminopeptidase
PAN99_RS03960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PAN99_RS03960	COG1263	PTS System
PAN99_RS03970	COG1368	sulfuric ester hydrolase activity
PAN99_RS03980	COG0071	Belongs to the small heat shock protein (HSP20) family
PAN99_RS03995	COG1263	PTS System
PAN99_RS03995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PAN99_RS04000	COG0366	Alpha amylase catalytic
PAN99_RS04005	COG2188	Transcriptional regulator
PAN99_RS04010	COG0778	Nitroreductase
PAN99_RS04025	COG0737	Belongs to the 5'-nucleotidase family
PAN99_RS04030	COG0693	protein deglycase activity
PAN99_RS04035	COG1609	Transcriptional regulator
PAN99_RS04050	COG2814	Major facilitator Superfamily
PAN99_RS04060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAN99_RS04065	COG4980	gas vesicle protein
PAN99_RS04070	COG1295	ribonuclease BN
PAN99_RS04075	COG0477	Major facilitator Superfamily
PAN99_RS04080	COG0387	Pfam Sodium calcium exchanger
PAN99_RS04090	COG0668	transmembrane transport
PAN99_RS04095	COG0535	radical SAM domain protein
PAN99_RS04105	COG0726	polysaccharide deacetylase
PAN99_RS04110	COG2084	Dehydrogenase
PAN99_RS04120	COG0598	Magnesium transport protein CorA
PAN99_RS04125	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PAN99_RS04130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAN99_RS04140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAN99_RS04145	COG4637	Psort location Cytoplasmic, score
PAN99_RS04150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PAN99_RS04155	COG0022	dehydrogenase e1 component
PAN99_RS04160	COG0508	dehydrogenase complex catalyzes the overall conversion of
PAN99_RS04165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PAN99_RS04170	COG3284	Transcriptional regulator
PAN99_RS04180	COG1486	melibiose metabolic process
PAN99_RS04185	COG1737	Transcriptional regulator
PAN99_RS04190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PAN99_RS04190	COG1263	PTS System
PAN99_RS04195	COG1132	(ABC) transporter
PAN99_RS04200	COG1132	(ABC) transporter
PAN99_RS04205	COG2259	Doxx family
PAN99_RS04210	COG2514	catechol 2,3-dioxygenase activity
PAN99_RS04220	COG1695	Transcriptional regulator
PAN99_RS04225	COG2249	NAD(P)H dehydrogenase (quinone) activity
PAN99_RS04230	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PAN99_RS04235	COG0574	Belongs to the PEP-utilizing enzyme family
PAN99_RS04235	COG3848	Pyruvate phosphate dikinase
PAN99_RS04240	COG2732	(Barnase) inhibitor
PAN99_RS04245	COG2318	DinB family
PAN99_RS04250	COG2814	Major facilitator Superfamily
PAN99_RS04255	COG1846	Transcriptional regulator
PAN99_RS04260	COG0392	lysyltransferase activity
PAN99_RS04260	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PAN99_RS04265	COG0384	phenazine biosynthesis protein PhzF
PAN99_RS04270	COG0778	Nitroreductase
PAN99_RS04285	COG1090	epimerase
PAN99_RS04300	COG2814	Major facilitator Superfamily
PAN99_RS04310	COG3591	Belongs to the peptidase S1B family
PAN99_RS04325	COG3103	Sh3 type 3 domain protein
PAN99_RS04330	COG5658	integral membrane protein
PAN99_RS04335	COG0596	Alpha beta hydrolase
PAN99_RS04340	COG0463	Glycosyl transferase, family 2
PAN99_RS04345	COG4485	Bacterial membrane protein, YfhO
PAN99_RS04350	COG1988	membrane-bound metal-dependent
PAN99_RS04355	COG1194	a g-specific adenine glycosylase
PAN99_RS04365	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS04385	COG1132	(ABC) transporter
PAN99_RS04390	COG4129	membrane
PAN99_RS04400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PAN99_RS04405	COG0735	belongs to the Fur family
PAN99_RS04520	COG3340	Belongs to the peptidase S51 family
PAN99_RS04530	COG0277	FAD linked oxidase domain protein
PAN99_RS04540	COG0747	negative chemotaxis
PAN99_RS04545	COG0601	transmembrane transport
PAN99_RS04550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAN99_RS04555	COG0444	Belongs to the ABC transporter superfamily
PAN99_RS04560	COG4608	Belongs to the ABC transporter superfamily
PAN99_RS04565	COG0753	catalase activity
PAN99_RS04575	COG1116	anion transmembrane transporter activity
PAN99_RS04580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PAN99_RS04585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PAN99_RS04605	COG1476	TRANSCRIPTIONal
PAN99_RS04615	COG3382	B3 4 domain protein
PAN99_RS04620	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PAN99_RS04630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PAN99_RS04635	COG0789	Transcriptional regulator
PAN99_RS04640	COG1664	Polymer-forming cytoskeletal
PAN99_RS04645	COG1664	Polymer-forming cytoskeletal
PAN99_RS04650	COG2766	serine protein kinase
PAN99_RS04660	COG1846	Transcriptional regulator
PAN99_RS04665	COG1566	PFAM secretion protein HlyD family protein
PAN99_RS04670	COG2814	Major facilitator Superfamily
PAN99_RS04675	COG0655	NAD(P)H dehydrogenase (quinone) activity
PAN99_RS04690	COG1725	Transcriptional regulator
PAN99_RS04695	COG1131	(ABC) transporter
PAN99_RS04700	COG1131	(ABC) transporter
PAN99_RS04705	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PAN99_RS04710	COG1278	Cold shock
PAN99_RS04715	COG1464	Belongs to the NlpA lipoprotein family
PAN99_RS04720	COG3706	GGDEF domain
PAN99_RS04725	COG1823	symporter activity
PAN99_RS04745	COG5577	PFAM Coat F domain
PAN99_RS04750	COG0737	Belongs to the 5'-nucleotidase family
PAN99_RS04750	COG1525	nuclease
PAN99_RS04750	COG4085	toxin activity
PAN99_RS04760	COG3764	Sortase (surface protein transpeptidase)
PAN99_RS04765	COG0564	pseudouridine synthase activity
PAN99_RS04775	COG0517	IMP dehydrogenase activity
PAN99_RS04780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PAN99_RS04785	COG3153	acetyltransferase
PAN99_RS04785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PAN99_RS04790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PAN99_RS04795	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PAN99_RS04800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PAN99_RS04810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PAN99_RS04815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PAN99_RS04830	COG0431	NADPH-dependent FMN reductase
PAN99_RS04845	COG0791	NLP P60 protein
PAN99_RS04845	COG1388	LysM domain
PAN99_RS04850	COG1959	2 iron, 2 sulfur cluster binding
PAN99_RS04860	COG2719	SpoVR family
PAN99_RS04865	COG1785	Belongs to the alkaline phosphatase family
PAN99_RS04870	COG0791	NLP P60 protein
PAN99_RS04870	COG1388	LysM domain
PAN99_RS04875	COG0583	DNA-binding transcription factor activity
PAN99_RS04880	COG0372	Belongs to the citrate synthase family
PAN99_RS04885	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS04890	COG0531	amino acid
PAN99_RS04895	COG0733	neurotransmitter:sodium symporter activity
PAN99_RS04910	COG1595	DNA-templated transcription, initiation
PAN99_RS04915	COG0204	Acyl-transferase
PAN99_RS04920	COG1253	flavin adenine dinucleotide binding
PAN99_RS04925	COG0789	Transcriptional regulator
PAN99_RS04930	COG0436	Aminotransferase
PAN99_RS04935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PAN99_RS04940	COG1253	flavin adenine dinucleotide binding
PAN99_RS04945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAN99_RS04950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAN99_RS04955	COG0584	glycerophosphoryl diester phosphodiesterase
PAN99_RS04965	COG0668	transmembrane transport
PAN99_RS04970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PAN99_RS04975	COG0726	polysaccharide deacetylase
PAN99_RS04980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PAN99_RS04985	COG3226	Transcriptional regulator
PAN99_RS04995	COG0589	response to stress
PAN99_RS05000	COG1132	(ABC) transporter
PAN99_RS05005	COG1132	(ABC) transporter
PAN99_RS05010	COG0702	epimerase
PAN99_RS05030	COG0189	ligase activity
PAN99_RS05035	COG0189	ligase activity
PAN99_RS05050	COG4335	DNA alkylation repair
PAN99_RS05055	COG0561	phosphatase activity
PAN99_RS05060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PAN99_RS05070	COG0475	glutathione-regulated potassium exporter activity
PAN99_RS05075	COG0490	domain, Protein
PAN99_RS05085	COG1024	Enoyl-CoA hydratase
PAN99_RS05095	COG4152	abc transporter atp-binding protein
PAN99_RS05100	COG1668	transmembrane transport
PAN99_RS05105	COG0420	3'-5' exonuclease activity
PAN99_RS05110	COG4717	serine-type aminopeptidase activity
PAN99_RS05125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PAN99_RS05160	COG4980	gas vesicle protein
PAN99_RS05175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PAN99_RS05180	COG0537	adenosine 5'-monophosphoramidase activity
PAN99_RS05185	COG1131	(ABC) transporter
PAN99_RS05190	COG4473	ABC transporter
PAN99_RS05200	COG1473	amidohydrolase
PAN99_RS05205	COG3069	C4-dicarboxylate transmembrane transporter activity
PAN99_RS05210	COG2329	Antibiotic biosynthesis monooxygenase
PAN99_RS05215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PAN99_RS05225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PAN99_RS05230	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PAN99_RS05235	COG1309	transcriptional regulator
PAN99_RS05240	COG1511	domain protein
PAN99_RS05245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAN99_RS05255	COG1363	Peptidase, m42
PAN99_RS05260	COG1301	dicarboxylic acid transport
PAN99_RS05270	COG1234	tRNA 3'-trailer cleavage
PAN99_RS05275	COG0095	Lipoate-protein ligase
PAN99_RS05280	COG0702	epimerase
PAN99_RS05285	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS05295	COG0501	Belongs to the peptidase M48B family
PAN99_RS05300	COG1404	Belongs to the peptidase S8 family
PAN99_RS05305	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
PAN99_RS05310	COG0406	alpha-ribazole phosphatase activity
PAN99_RS05315	COG0183	Belongs to the thiolase family
PAN99_RS05320	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS05325	COG1268	BioY protein
PAN99_RS05330	COG0840	transmembrane signaling receptor activity
PAN99_RS05335	COG0723	plastoquinol--plastocyanin reductase activity
PAN99_RS05335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAN99_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS05350	COG4903	ComK protein
PAN99_RS05360	COG5646	InterPro IPR014922
PAN99_RS05380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAN99_RS05395	COG0398	Pfam SNARE associated Golgi protein
PAN99_RS05400	COG0681	Belongs to the peptidase S26 family
PAN99_RS05405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PAN99_RS05410	COG1846	Transcriptional regulator
PAN99_RS05415	COG3180	Ammonia monooxygenase
PAN99_RS05420	COG2814	Major facilitator Superfamily
PAN99_RS05430	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
PAN99_RS05435	COG2323	membrane
PAN99_RS05450	COG0420	3'-5' exonuclease activity
PAN99_RS05455	COG0419	ATPase involved in DNA repair
PAN99_RS05460	COG1403	HNH endonuclease
PAN99_RS05500	COG0179	Fumarylacetoacetate (FAA) hydrolase
PAN99_RS05520	COG0367	asparagine synthase
PAN99_RS05525	COG1562	ergosterol biosynthetic process
PAN99_RS05530	COG0534	Mate efflux family protein
PAN99_RS05535	COG2207	Transcriptional regulator
PAN99_RS05535	COG1917	Cupin 2, conserved barrel domain protein
PAN99_RS05540	COG1609	Transcriptional regulator
PAN99_RS05545	COG0673	inositol 2-dehydrogenase activity
PAN99_RS05555	COG2318	DinB family
PAN99_RS05560	COG1357	PFAM Pentapeptide repeats (8 copies)
PAN99_RS05565	COG2153	protein acetylation
PAN99_RS05570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PAN99_RS05570	COG0646	methionine synthase
PAN99_RS05580	COG2996	Protein conserved in bacteria
PAN99_RS05585	COG1744	ABC transporter substrate-binding protein PnrA-like
PAN99_RS05590	COG0840	transmembrane signaling receptor activity
PAN99_RS05600	COG1307	EDD domain protein, DegV family
PAN99_RS05605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAN99_RS05625	COG0561	phosphatase activity
PAN99_RS05630	COG1073	alpha beta
PAN99_RS05635	COG2151	metal-sulfur cluster biosynthetic enzyme
PAN99_RS05645	COG0277	FAD linked oxidase domain protein
PAN99_RS05650	COG2271	Major facilitator Superfamily
PAN99_RS05660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PAN99_RS05670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PAN99_RS05675	COG0505	Belongs to the CarA family
PAN99_RS05680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PAN99_RS05685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PAN99_RS05700	COG2267	carboxylic ester hydrolase activity
PAN99_RS05710	COG1744	ABC transporter substrate-binding protein PnrA-like
PAN99_RS05725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAN99_RS05730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PAN99_RS05735	COG5504	Zn-dependent protease
PAN99_RS05740	COG0444	Belongs to the ABC transporter superfamily
PAN99_RS05745	COG4608	Belongs to the ABC transporter superfamily
PAN99_RS05755	COG0601	transmembrane transport
PAN99_RS05760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAN99_RS05780	COG0180	Tryptophanyl-tRNA synthetase
PAN99_RS05785	COG4166	transmembrane transport
PAN99_RS05795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAN99_RS05800	COG0444	Belongs to the ABC transporter superfamily
PAN99_RS05805	COG4608	Belongs to the ABC transporter superfamily
PAN99_RS05815	COG0456	acetyltransferase
PAN99_RS05820	COG1393	Belongs to the ArsC family
PAN99_RS05825	COG0861	Integral membrane protein TerC family
PAN99_RS05830	COG4862	establishment of competence for transformation
PAN99_RS05835	COG4469	Competence protein
PAN99_RS05840	COG1164	Oligoendopeptidase f
PAN99_RS05850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PAN99_RS05855	COG2346	COG2346, Truncated hemoglobins
PAN99_RS05860	COG0741	lytic transglycosylase activity
PAN99_RS05865	COG4116	CYTH
PAN99_RS05875	COG2357	RelA SpoT domain protein
PAN99_RS05880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PAN99_RS05885	COG0564	pseudouridine synthase activity
PAN99_RS05895	COG0475	glutathione-regulated potassium exporter activity
PAN99_RS05895	COG0569	domain protein
PAN99_RS05900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PAN99_RS05905	COG0352	thiamine-phosphate diphosphorylase activity
PAN99_RS05910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAN99_RS05915	COG2104	thiamine diphosphate biosynthetic process
PAN99_RS05925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PAN99_RS05930	COG0351	phosphomethylpyrimidine kinase
PAN99_RS05935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PAN99_RS05990	COG0210	DNA helicase
PAN99_RS06010	COG1131	(ABC) transporter
PAN99_RS06020	COG2153	protein acetylation
PAN99_RS06030	COG2382	esterase
PAN99_RS06035	COG0626	cystathionine gamma-synthase activity
PAN99_RS06040	COG0626	cystathionine gamma-synthase activity
PAN99_RS06075	COG5444	nuclease activity
PAN99_RS06120	COG2367	Beta-lactamase
PAN99_RS06125	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PAN99_RS06135	COG1846	Transcriptional regulator
PAN99_RS06145	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
PAN99_RS06150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PAN99_RS06155	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PAN99_RS06160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PAN99_RS06160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PAN99_RS06165	COG1447	Phosphotransferase system cellobiose-specific component IIA
PAN99_RS06175	COG1349	DNA-binding transcription factor activity
PAN99_RS06190	COG1285	pathogenesis
PAN99_RS06200	COG2205	protein histidine kinase activity
PAN99_RS06210	COG3383	formate dehydrogenase (NAD+) activity
PAN99_RS06215	COG2427	Protein of unknown function (DUF1641)
PAN99_RS06220	COG2124	cytochrome p450
PAN99_RS06225	COG1819	glycosyl
PAN99_RS06235	COG1587	Uroporphyrinogen-III synthase
PAN99_RS06240	COG0390	transport system, permease component
PAN99_RS06245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PAN99_RS06250	COG0697	spore germination
PAN99_RS06255	COG4297	protein containing double-stranded beta helix domain
PAN99_RS06265	COG1252	NADH dehydrogenase
PAN99_RS06275	COG2211	Major facilitator Superfamily
PAN99_RS06280	COG1609	Transcriptional regulator
PAN99_RS06285	COG0246	Mannitol dehydrogenase
PAN99_RS06290	COG2721	sulfolactate sulfo-lyase activity
PAN99_RS06295	COG0745	RESPONSE REGULATOR receiver
PAN99_RS06300	COG2770	Histidine kinase
PAN99_RS06300	COG2205	protein histidine kinase activity
PAN99_RS06315	COG0730	response to heat
PAN99_RS06320	COG2318	DinB family
PAN99_RS06325	COG0457	Tetratricopeptide repeat
PAN99_RS06335	COG1388	LysM domain
PAN99_RS06335	COG5632	N-Acetylmuramoyl-L-alanine amidase
PAN99_RS06335	COG3409	Peptidoglycan-binding domain 1 protein
PAN99_RS06345	COG4195	phage-related replication protein
PAN99_RS06350	COG2856	Zn peptidase
PAN99_RS06355	COG1396	sequence-specific DNA binding
PAN99_RS06365	COG1522	sequence-specific DNA binding
PAN99_RS06370	COG1484	DNA-dependent DNA replication
PAN99_RS06390	COG1595	DNA-templated transcription, initiation
PAN99_RS06395	COG3728	DNA packaging
PAN99_RS06395	COG5484	DNA packaging
PAN99_RS06400	COG1783	phage Terminase large subunit
PAN99_RS06405	COG5518	Phage portal protein
PAN99_RS06410	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PAN99_RS06415	COG4653	Phage capsid family
PAN99_RS06465	COG3953	SLT domain
PAN99_RS06465	COG5412	phage tail tape measure protein
PAN99_RS06465	COG3953	SLT domain
PAN99_RS06465	COG5412	phage tail tape measure protein
PAN99_RS06465	COG3953	SLT domain
PAN99_RS06465	COG5412	phage tail tape measure protein
PAN99_RS06470	COG1652	LysM domain
PAN99_RS06475	COG4193	domain, Protein
PAN99_RS06485	COG3628	GPW Gp25 family protein
PAN99_RS06490	COG3299	homolog of phage Mu protein gp47
PAN99_RS06495	COG3778	Protein conserved in bacteria
PAN99_RS06535	COG5632	N-Acetylmuramoyl-L-alanine amidase
PAN99_RS06535	COG3409	Peptidoglycan-binding domain 1 protein
PAN99_RS06550	COG0306	phosphate transporter
PAN99_RS06555	COG1392	Phosphate transport regulator
PAN99_RS06560	COG0531	amino acid
PAN99_RS06565	COG0346	lactoylglutathione lyase activity
PAN99_RS06570	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PAN99_RS06575	COG0463	Glycosyl transferase, family 2
PAN99_RS06580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAN99_RS06585	COG0477	Major facilitator Superfamily
PAN99_RS06590	COG2362	D-Aminopeptidase
PAN99_RS06595	COG0601	transmembrane transport
PAN99_RS06600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAN99_RS06605	COG0444	Belongs to the ABC transporter superfamily
PAN99_RS06610	COG4166	transmembrane transport
PAN99_RS06615	COG1619	proteins homologs of microcin C7 resistance protein MccF
PAN99_RS06620	COG4948	Mandelate Racemase Muconate Lactonizing
PAN99_RS06625	COG0791	NLP P60 protein
PAN99_RS06630	COG4608	Belongs to the ABC transporter superfamily
PAN99_RS06635	COG2706	6-phosphogluconolactonase activity
PAN99_RS06640	COG1834	amidinotransferase
PAN99_RS06645	COG1607	acyl-coa hydrolase
PAN99_RS06650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PAN99_RS06655	COG2076	Multidrug Resistance protein
PAN99_RS06660	COG2076	Multidrug Resistance protein
PAN99_RS06665	COG0788	formyltetrahydrofolate deformylase activity
PAN99_RS06670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PAN99_RS06685	COG1846	Transcriptional regulator
PAN99_RS06690	COG1764	response to oxidative stress
PAN99_RS06705	COG0463	Glycosyl transferase, family 2
PAN99_RS06705	COG0457	Tetratricopeptide repeat
PAN99_RS06715	COG2814	Major facilitator Superfamily
PAN99_RS06720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PAN99_RS06730	COG1404	Belongs to the peptidase S8 family
PAN99_RS06735	COG1366	Belongs to the anti-sigma-factor antagonist family
PAN99_RS06740	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAN99_RS06745	COG1122	ATPase activity
PAN99_RS06750	COG4721	ABC-type cobalt transport system, permease component
PAN99_RS06755	COG3858	chitin binding
PAN99_RS06755	COG1388	LysM domain
PAN99_RS06765	COG2239	Acts as a magnesium transporter
PAN99_RS06770	COG0789	Transcriptional regulator
PAN99_RS06785	COG1846	Transcriptional regulator
PAN99_RS06790	COG0726	polysaccharide deacetylase
PAN99_RS06795	COG1793	dna ligase
PAN99_RS06795	COG3285	dna ligase
PAN99_RS06800	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PAN99_RS06805	COG0586	Pfam SNARE associated Golgi protein
PAN99_RS06815	COG1191	sigma factor activity
PAN99_RS06840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PAN99_RS06845	COG2323	membrane
PAN99_RS06855	COG3594	Acyltransferase
PAN99_RS06860	COG5002	protein histidine kinase activity
PAN99_RS06865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PAN99_RS06885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PAN99_RS06890	COG0436	Aminotransferase
PAN99_RS06920	COG3852	Histidine kinase
PAN99_RS06925	COG1846	Transcriptional regulator
PAN99_RS06930	COG1360	Flagellar Motor Protein
PAN99_RS06935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PAN99_RS06940	COG0542	response to heat
PAN99_RS06945	COG3949	Membrane
PAN99_RS06960	COG0720	synthase
PAN99_RS06965	COG0602	queuosine metabolic process
PAN99_RS06980	COG4873	Protein conserved in bacteria
PAN99_RS06990	COG3773	Cell wall hydrolase
PAN99_RS06995	COG2244	polysaccharide biosynthetic process
PAN99_RS07000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PAN99_RS07005	COG2217	Heavy metal translocating P-type atpase
PAN99_RS07010	COG0006	proline dipeptidase activity
PAN99_RS07020	COG1609	Transcriptional regulator
PAN99_RS07025	COG3711	transcriptional antiterminator
PAN99_RS07030	COG1263	PTS System
PAN99_RS07030	COG2190	(PTS) system
PAN99_RS07030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PAN99_RS07035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PAN99_RS07040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PAN99_RS07050	COG1533	DNA photolyase activity
PAN99_RS07055	COG0840	transmembrane signaling receptor activity
PAN99_RS07060	COG2084	Dehydrogenase
PAN99_RS07065	COG2340	Cysteine-rich secretory protein family
PAN99_RS07070	COG0768	penicillin binding
PAN99_RS07075	COG4191	Histidine kinase
PAN99_RS07080	COG0436	Aminotransferase
PAN99_RS07090	COG0784	Response regulator, receiver
PAN99_RS07090	COG0835	chemotaxis
PAN99_RS07100	COG2814	Major facilitator Superfamily
PAN99_RS07105	COG1376	ErfK ybiS ycfS ynhG family protein
PAN99_RS07110	COG1408	metallophosphoesterase
PAN99_RS07115	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS07125	COG2200	EAL domain
PAN99_RS07130	COG4703	Protein of unknown function (DUF1797)
PAN99_RS07135	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
PAN99_RS07145	COG0517	IMP dehydrogenase activity
PAN99_RS07150	COG0583	DNA-binding transcription factor activity
PAN99_RS07155	COG0716	FMN binding
PAN99_RS07165	COG0716	FMN binding
PAN99_RS07185	COG0668	transmembrane transport
PAN99_RS07190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PAN99_RS07210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PAN99_RS07215	COG0303	'Molybdopterin
PAN99_RS07220	COG1763	Mo-molybdopterin cofactor biosynthetic process
PAN99_RS07225	COG0314	molybdopterin synthase activity
PAN99_RS07230	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PAN99_RS07240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAN99_RS07245	COG1136	(ABC) transporter
PAN99_RS07250	COG0577	efflux transmembrane transporter activity
PAN99_RS07255	COG1349	DNA-binding transcription factor activity
PAN99_RS07260	COG1105	Belongs to the carbohydrate kinase PfkB family
PAN99_RS07265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PAN99_RS07265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PAN99_RS07265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PAN99_RS07270	COG0681	Belongs to the peptidase S26 family
PAN99_RS07280	COG0488	(ABC) transporter
PAN99_RS07285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAN99_RS07290	COG2309	aminopeptidase activity
PAN99_RS07300	COG1077	Cell shape determining protein MreB Mrl
PAN99_RS07305	COG2002	toxin-antitoxin pair type II binding
PAN99_RS07310	COG3852	Histidine kinase
PAN99_RS07315	COG2105	PFAM AIG2 family protein
PAN99_RS07315	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
PAN99_RS07320	COG0569	domain protein
PAN99_RS07330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAN99_RS07340	COG0561	phosphatase activity
PAN99_RS07345	COG0242	peptide deformylase activity
PAN99_RS07355	COG0497	DNA recombination
PAN99_RS07365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS07365	COG3321	synthase
PAN99_RS07365	COG4221	oxidoreductase activity
PAN99_RS07365	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS07370	COG3321	synthase
PAN99_RS07370	COG0300	oxidoreductase activity
PAN99_RS07370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS07370	COG4221	oxidoreductase activity
PAN99_RS07375	COG4221	oxidoreductase activity
PAN99_RS07375	COG3321	synthase
PAN99_RS07375	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS07375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS07380	COG0300	oxidoreductase activity
PAN99_RS07380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS07380	COG3321	synthase
PAN99_RS07380	COG4221	oxidoreductase activity
PAN99_RS07385	COG4221	oxidoreductase activity
PAN99_RS07385	COG3321	synthase
PAN99_RS07385	COG0300	oxidoreductase activity
PAN99_RS07385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS07390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS07390	COG0300	oxidoreductase activity
PAN99_RS07390	COG3321	synthase
PAN99_RS07390	COG4221	oxidoreductase activity
PAN99_RS07395	COG4221	oxidoreductase activity
PAN99_RS07395	COG3321	synthase
PAN99_RS07395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS07400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PAN99_RS07405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PAN99_RS07410	COG0022	dehydrogenase e1 component
PAN99_RS07415	COG0508	dehydrogenase complex catalyzes the overall conversion of
PAN99_RS07420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PAN99_RS07425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PAN99_RS07440	COG1982	Orn Lys Arg decarboxylase major
PAN99_RS07460	COG0483	inositol monophosphate 1-phosphatase activity
PAN99_RS07470	COG3227	Zinc metalloprotease (Elastase)
PAN99_RS07485	COG1595	DNA-templated transcription, initiation
PAN99_RS07505	COG1217	gtp-binding protein TYPA
PAN99_RS07515	COG4896	Protein conserved in bacteria
PAN99_RS07525	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PAN99_RS07530	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PAN99_RS07535	COG2066	Belongs to the glutaminase family
PAN99_RS07545	COG0772	Belongs to the SEDS family
PAN99_RS07550	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PAN99_RS07565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PAN99_RS07565	COG2010	Cytochrome c
PAN99_RS07570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PAN99_RS07575	COG1845	cytochrome c oxidase, subunit III
PAN99_RS07580	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PAN99_RS07585	COG3336	cytochrome c oxidase
PAN99_RS07595	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
PAN99_RS07600	COG2340	Cysteine-rich secretory protein family
PAN99_RS07615	COG3679	Belongs to the UPF0342 family
PAN99_RS07630	COG0742	ribosomal rna small subunit methyltransferase
PAN99_RS07640	COG3314	Sporulation integral membrane protein YlbJ
PAN99_RS07645	COG1752	Esterase of the alpha-beta hydrolase superfamily
PAN99_RS07650	COG3480	Lon protease (S16) C-terminal proteolytic domain
PAN99_RS07660	COG1399	metal-binding, possibly nucleic acid-binding protein
PAN99_RS07680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAN99_RS07700	COG4839	cell division protein FtsL
PAN99_RS07705	COG0768	penicillin binding
PAN99_RS07710	COG0768	penicillin binding
PAN99_RS07730	COG0772	Belongs to the SEDS family
PAN99_RS07745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PAN99_RS07750	COG0849	cell division
PAN99_RS07755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PAN99_RS07760	COG4412	M6 family metalloprotease domain protein
PAN99_RS07760	COG1404	Belongs to the peptidase S8 family
PAN99_RS07770	COG1191	sigma factor activity
PAN99_RS07775	COG1191	sigma factor activity
PAN99_RS07780	COG1119	ATPase activity
PAN99_RS07785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PAN99_RS07790	COG1873	PFAM PRC-barrel domain
PAN99_RS07795	COG1496	oxidoreductase activity
PAN99_RS07800	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PAN99_RS07810	COG0762	integral membrane protein
PAN99_RS07815	COG2302	S4 RNA-binding domain
PAN99_RS07820	COG3599	regulation of cell shape
PAN99_RS07825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PAN99_RS07830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PAN99_RS07840	COG0564	pseudouridine synthase activity
PAN99_RS07850	COG2233	PERMEase
PAN99_RS07860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PAN99_RS07865	COG0505	Belongs to the CarA family
PAN99_RS07870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PAN99_RS07885	COG0284	orotidine-5'-phosphate decarboxylase activity
PAN99_RS07890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PAN99_RS07900	COG0306	phosphate transporter
PAN99_RS07915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PAN99_RS07920	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
PAN99_RS07925	COG1648	precorrin-2 dehydrogenase activity
PAN99_RS07935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PAN99_RS07940	COG1561	YicC-like family, N-terminal region
PAN99_RS07950	COG0194	GDP metabolic process
PAN99_RS07960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PAN99_RS07965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PAN99_RS07970	COG0242	peptide deformylase activity
PAN99_RS07980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PAN99_RS07980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PAN99_RS07990	COG0631	protein serine/threonine phosphatase activity
PAN99_RS07995	COG0515	serine threonine protein kinase
PAN99_RS07995	COG2815	serine threonine protein kinase
PAN99_RS08005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PAN99_RS08010	COG1564	THIamine pyrophosphokinase
PAN99_RS08025	COG1302	Protein conserved in bacteria
PAN99_RS08030	COG1461	Dihydroxyacetone kinase
PAN99_RS08035	COG1760	l-serine dehydratase
PAN99_RS08040	COG1760	l-serine dehydratase
PAN99_RS08045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PAN99_RS08060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PAN99_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS08080	COG1196	nuclear chromosome segregation
PAN99_RS08085	COG0552	protein localization to endoplasmic reticulum
PAN99_RS08100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PAN99_RS08110	COG1837	Belongs to the UPF0109 family
PAN99_RS08135	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PAN99_RS08150	COG2257	FlhB HrpN YscU SpaS Family
PAN99_RS08160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PAN99_RS08165	COG0758	DNA mediated transformation
PAN99_RS08170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PAN99_RS08180	COG4974	Belongs to the 'phage' integrase family
PAN99_RS08200	COG1815	bacterial-type flagellum-dependent cell motility
PAN99_RS08205	COG1558	bacterial-type flagellum-dependent cell motility
PAN99_RS08210	COG1677	Flagellar hook-basal body complex protein FliE
PAN99_RS08215	COG1766	The M ring may be actively involved in energy transduction
PAN99_RS08220	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PAN99_RS08225	COG1317	bacterial-type flagellum organization
PAN99_RS08230	COG1157	protein secretion by the type III secretion system
PAN99_RS08235	COG2882	bacterial-type flagellum organization
PAN99_RS08240	COG3334	PFAM MgtE intracellular
PAN99_RS08245	COG3144	bacterial-type flagellum assembly
PAN99_RS08250	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PAN99_RS08255	COG4786	Flagellar basal body rod
PAN99_RS08260	COG1582	Flagellar protein (FlbD)
PAN99_RS08265	COG1580	Controls the rotational direction of flagella during chemotaxis
PAN99_RS08270	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PAN99_RS08275	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PAN99_RS08275	COG1776	CheC inhibitor of MCP methylation
PAN99_RS08280	COG2201	protein-glutamate methylesterase activity
PAN99_RS08285	COG3190	flagellar
PAN99_RS08290	COG1338	Plays a role in the flagellum-specific transport system
PAN99_RS08295	COG1987	bacterial-type flagellum assembly
PAN99_RS08300	COG1684	flagellar biosynthetic protein fliR
PAN99_RS08305	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PAN99_RS08310	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PAN99_RS08315	COG1419	protein localization to endoplasmic reticulum
PAN99_RS08320	COG0455	bacterial-type flagellum organization
PAN99_RS08325	COG2201	protein-glutamate methylesterase activity
PAN99_RS08330	COG0643	Histidine kinase
PAN99_RS08330	COG2198	Histidine kinase
PAN99_RS08335	COG0835	chemotaxis
PAN99_RS08340	COG1776	CheC inhibitor of MCP methylation
PAN99_RS08350	COG1191	sigma factor activity
PAN99_RS08380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PAN99_RS08385	COG4589	Belongs to the CDS family
PAN99_RS08395	COG0750	zinc metalloprotease
PAN99_RS08415	COG0195	Participates in both transcription termination and antitermination
PAN99_RS08420	COG2740	Nucleic-acid-binding protein implicated in transcription termination
PAN99_RS08425	COG1358	cellular component organization or biogenesis
PAN99_RS08435	COG1550	Protein conserved in bacteria
PAN99_RS08450	COG0196	riboflavin kinase activity
PAN99_RS08465	COG0726	polysaccharide deacetylase
PAN99_RS08470	COG0612	Peptidase, M16
PAN99_RS08475	COG1873	PFAM PRC-barrel domain
PAN99_RS08480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAN99_RS08485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PAN99_RS08490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PAN99_RS08495	COG0527	aspartate kinase activity
PAN99_RS08505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAN99_RS08510	COG0740	serine-type endopeptidase activity
PAN99_RS08520	COG1674	ftsk spoiiie
PAN99_RS08520	COG4980	gas vesicle protein
PAN99_RS08525	COG2188	Transcriptional regulator
PAN99_RS08530	COG2814	Major facilitator Superfamily
PAN99_RS08535	COG1846	Transcriptional regulator
PAN99_RS08540	COG2409	Drug exporters of the RND superfamily
PAN99_RS08540	COG1033	growth of symbiont in host cell
PAN99_RS08545	COG0612	Peptidase, M16
PAN99_RS08550	COG0612	Peptidase, M16
PAN99_RS08555	COG0300	oxidoreductase activity
PAN99_RS08570	COG1426	Protein conserved in bacteria
PAN99_RS08575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PAN99_RS08590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PAN99_RS08600	COG1692	metallophosphoesterase
PAN99_RS08605	COG2359	stage V sporulation protein S
PAN99_RS08625	COG4550	Control of competence regulator ComK, YlbF/YmcA
PAN99_RS08670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS08675	COG3425	synthase
PAN99_RS08680	COG1024	Enoyl-CoA hydratase
PAN99_RS08685	COG1024	Enoyl-CoA hydratase
PAN99_RS08690	COG0300	oxidoreductase activity
PAN99_RS08690	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS08690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS08690	COG3321	synthase
PAN99_RS08695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS08695	COG3321	synthase
PAN99_RS08695	COG4221	oxidoreductase activity
PAN99_RS08695	COG0300	oxidoreductase activity
PAN99_RS08700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS08700	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS08700	COG3321	synthase
PAN99_RS08700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS08700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAN99_RS08700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS08700	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS08700	COG3321	synthase
PAN99_RS08700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAN99_RS08700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS08705	COG4221	oxidoreductase activity
PAN99_RS08705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS08705	COG3321	synthase
PAN99_RS08710	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
PAN99_RS08710	COG3321	synthase
PAN99_RS08710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS08710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PAN99_RS08715	COG2124	cytochrome p450
PAN99_RS08720	COG3209	COG3209 Rhs family protein
PAN99_RS08725	COG3619	membrane
PAN99_RS08735	COG1404	Belongs to the peptidase S8 family
PAN99_RS08745	COG4195	phage-related replication protein
PAN99_RS08750	COG1764	response to oxidative stress
PAN99_RS08760	COG2076	Multidrug Resistance protein
PAN99_RS08800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAN99_RS08805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAN99_RS08810	COG4112	unkown
PAN99_RS08815	COG0860	N-Acetylmuramoyl-L-alanine amidase
PAN99_RS08820	COG0464	growth
PAN99_RS08825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PAN99_RS08830	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
PAN99_RS08835	COG0789	Transcriptional regulator
PAN99_RS08840	COG0174	glutamine synthetase
PAN99_RS08885	COG2211	Major facilitator Superfamily
PAN99_RS08890	COG3507	Belongs to the glycosyl hydrolase 43 family
PAN99_RS08905	COG1070	Carbohydrate kinase
PAN99_RS08910	COG0574	Belongs to the PEP-utilizing enzyme family
PAN99_RS08910	COG3848	Pyruvate phosphate dikinase
PAN99_RS08930	COG1064	alcohol dehydrogenase
PAN99_RS08950	COG0456	acetyltransferase
PAN99_RS08970	COG3397	chitin binding
PAN99_RS08995	COG5434	Belongs to the glycosyl hydrolase 28 family
PAN99_RS09000	COG0756	dUTP diphosphatase activity
PAN99_RS09005	COG4195	phage-related replication protein
PAN99_RS09040	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PAN99_RS09050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PAN99_RS09070	COG0785	Cytochrome C biogenesis protein
PAN99_RS09075	COG2201	protein-glutamate methylesterase activity
PAN99_RS09080	COG4846	Membrane protein involved in cytochrome C biogenesis
PAN99_RS09090	COG0071	Belongs to the small heat shock protein (HSP20) family
PAN99_RS09105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PAN99_RS09110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PAN99_RS09130	COG0824	Thioesterase
PAN99_RS09140	COG4841	protein insertion into membrane
PAN99_RS09150	COG1832	CoA-binding protein
PAN99_RS09155	COG0187	DNA topoisomerase II activity
PAN99_RS09160	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAN99_RS09175	COG1115	amino acid carrier protein
PAN99_RS09185	COG1063	alcohol dehydrogenase
PAN99_RS09190	COG0800	Aldolase
PAN99_RS09195	COG1312	Catalyzes the dehydration of D-mannonate
PAN99_RS09200	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS09205	COG1609	Transcriptional regulator
PAN99_RS09210	COG2271	Major facilitator Superfamily
PAN99_RS09255	COG2205	protein histidine kinase activity
PAN99_RS09260	COG0745	RESPONSE REGULATOR receiver
PAN99_RS09270	COG3507	Belongs to the glycosyl hydrolase 43 family
PAN99_RS09295	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS09300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PAN99_RS09305	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PAN99_RS09310	COG2610	gluconate transmembrane transporter activity
PAN99_RS09315	COG2124	cytochrome p450
PAN99_RS09335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PAN99_RS09345	COG2246	polysaccharide biosynthetic process
PAN99_RS09350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PAN99_RS09355	COG0586	Pfam SNARE associated Golgi protein
PAN99_RS09360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PAN99_RS09365	COG1024	Enoyl-CoA hydratase
PAN99_RS09370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PAN99_RS09375	COG0511	ligase activity, forming carbon-carbon bonds
PAN99_RS09380	COG0439	Biotin carboxylase
PAN99_RS09385	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS09390	COG1960	acyl-CoA dehydrogenase activity
PAN99_RS09395	COG1649	PFAM Uncharacterised BCR, COG1649
PAN99_RS09405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS09405	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
PAN99_RS09410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS09415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS09420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS09425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS09430	COG2027	D-alanyl-D-alanine carboxypeptidase
PAN99_RS09435	COG2017	converts alpha-aldose to the beta-anomer
PAN99_RS09440	COG0534	Mate efflux family protein
PAN99_RS09450	COG5444	nuclease activity
PAN99_RS09495	COG5434	Belongs to the glycosyl hydrolase 28 family
PAN99_RS09500	COG1705	Flagellar rod assembly protein muramidase FlgJ
PAN99_RS09510	COG3953	SLT domain
PAN99_RS09510	COG5280	Phage tail tape measure protein TP901
PAN99_RS09590	COG0582	viral genome integration into host DNA
PAN99_RS09595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PAN99_RS09725	COG0582	viral genome integration into host DNA
PAN99_RS09730	COG0166	Belongs to the GPI family
PAN99_RS09735	COG0405	Gamma-glutamyltransferase
PAN99_RS09740	COG2814	Major facilitator Superfamily
PAN99_RS09745	COG0640	Transcriptional regulator
PAN99_RS09760	COG0604	alcohol dehydrogenase
PAN99_RS09765	COG0493	'glutamate synthase
PAN99_RS09770	COG0067	glutamate synthase
PAN99_RS09770	COG0070	glutamate synthase
PAN99_RS09770	COG0069	glutamate synthase activity
PAN99_RS09775	COG0583	DNA-binding transcription factor activity
PAN99_RS09780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PAN99_RS09795	COG0300	oxidoreductase activity
PAN99_RS09800	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PAN99_RS09810	COG2814	Major facilitator Superfamily
PAN99_RS09815	COG1070	Carbohydrate kinase
PAN99_RS09820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PAN99_RS09825	COG0243	molybdopterin cofactor binding
PAN99_RS09845	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS09850	COG1733	regulation of RNA biosynthetic process
PAN99_RS09855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAN99_RS09860	COG0662	Cupin 2, conserved barrel domain protein
PAN99_RS09860	COG2207	Transcriptional regulator
PAN99_RS09865	COG1309	transcriptional regulator
PAN99_RS09870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAN99_RS09880	COG0640	Transcriptional regulator
PAN99_RS09885	COG0741	lytic transglycosylase activity
PAN99_RS09890	COG2322	membrane
PAN99_RS09905	COG1619	proteins homologs of microcin C7 resistance protein MccF
PAN99_RS09915	COG1388	LysM domain
PAN99_RS09915	COG3584	3D domain protein
PAN99_RS09920	COG0514	ATP-dependent DNA helicase (RecQ)
PAN99_RS09930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PAN99_RS09935	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PAN99_RS09950	COG0071	Belongs to the small heat shock protein (HSP20) family
PAN99_RS09980	COG1012	belongs to the aldehyde dehydrogenase family
PAN99_RS09985	COG1657	PFAM Prenyltransferase squalene oxidase
PAN99_RS09990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PAN99_RS09995	COG0733	neurotransmitter:sodium symporter activity
PAN99_RS10000	COG0385	Bile acid
PAN99_RS10005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAN99_RS10010	COG0508	dehydrogenase complex catalyzes the overall conversion of
PAN99_RS10020	COG4548	von Willebrand factor, type A
PAN99_RS10025	COG0714	Associated with various cellular activities
PAN99_RS10030	COG2032	superoxide dismutase activity
PAN99_RS10035	COG0791	NLP P60 protein
PAN99_RS10035	COG1388	LysM domain
PAN99_RS10040	COG1819	glycosyl
PAN99_RS10045	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PAN99_RS10050	COG0534	Mate efflux family protein
PAN99_RS10055	COG1366	Belongs to the anti-sigma-factor antagonist family
PAN99_RS10060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PAN99_RS10065	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PAN99_RS10075	COG2962	Rard protein
PAN99_RS10090	COG1942	4-Oxalocrotonate Tautomerase
PAN99_RS10100	COG1733	regulation of RNA biosynthetic process
PAN99_RS10105	COG0778	Nitroreductase
PAN99_RS10110	COG0400	carboxylic ester hydrolase activity
PAN99_RS10115	COG0346	lactoylglutathione lyase activity
PAN99_RS10125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAN99_RS10135	COG2723	6-phospho-beta-galactosidase activity
PAN99_RS10140	COG2188	Transcriptional regulator
PAN99_RS10145	COG3409	Peptidoglycan-binding domain 1 protein
PAN99_RS10145	COG0793	Belongs to the peptidase S41A family
PAN99_RS10150	COG2226	methyltransferase
PAN99_RS10160	COG1876	peptidase activity
PAN99_RS10180	COG0671	phosphoesterase, PA-phosphatase related
PAN99_RS10215	COG1509	lysine 2,3-aminomutase activity
PAN99_RS10220	COG0456	acetyltransferase
PAN99_RS10225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PAN99_RS10230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PAN99_RS10235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PAN99_RS10240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PAN99_RS10245	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PAN99_RS10255	COG0456	acetyltransferase
PAN99_RS10260	COG0463	Glycosyl transferase, family 2
PAN99_RS10275	COG4641	Protein conserved in bacteria
PAN99_RS10285	COG1086	Polysaccharide biosynthesis protein
PAN99_RS10300	COG1846	Transcriptional regulator
PAN99_RS10305	COG4698	Protein conserved in bacteria
PAN99_RS10310	COG2755	lipolytic protein G-D-S-L family
PAN99_RS10315	COG1999	signal sequence binding
PAN99_RS10325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PAN99_RS10330	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PAN99_RS10335	COG1272	protein, Hemolysin III
PAN99_RS10340	COG0204	Acyl-transferase
PAN99_RS10345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PAN99_RS10360	COG2136	Putative SAM-dependent methyltransferase
PAN99_RS10360	COG2521	methyltransferase
PAN99_RS10375	COG1413	lyase activity
PAN99_RS10380	COG1418	mRNA catabolic process
PAN99_RS10385	COG0386	Belongs to the glutathione peroxidase family
PAN99_RS10395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PAN99_RS10405	COG1278	Cold shock
PAN99_RS10425	COG0328	RNA-DNA hybrid ribonuclease activity
PAN99_RS10430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PAN99_RS10435	COG0328	RNA-DNA hybrid ribonuclease activity
PAN99_RS10445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PAN99_RS10460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PAN99_RS10470	COG1755	Isoprenylcysteine carboxyl methyltransferase
PAN99_RS10475	COG3424	synthase
PAN99_RS10500	COG1335	isochorismatase
PAN99_RS10510	COG2233	PERMEase
PAN99_RS10520	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PAN99_RS10525	COG1199	ATP-dependent helicase activity
PAN99_RS10540	COG0116	Belongs to the methyltransferase superfamily
PAN99_RS10570	COG3359	exonuclease
PAN99_RS10575	COG1111	helicase
PAN99_RS10575	COG1205	dead DEAH box helicase
PAN99_RS10580	COG2190	(PTS) system
PAN99_RS10585	COG0071	Belongs to the small heat shock protein (HSP20) family
PAN99_RS10625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PAN99_RS10625	COG4499	WXG100 protein secretion system (Wss), protein YukC
PAN99_RS10635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PAN99_RS10640	COG3935	DnaD domain protein
PAN99_RS10650	COG0436	Aminotransferase
PAN99_RS10655	COG5353	protein conserved in bacteria
PAN99_RS10665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PAN99_RS10665	COG1199	ATP-dependent helicase activity
PAN99_RS10695	COG0438	transferase activity, transferring glycosyl groups
PAN99_RS10700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PAN99_RS10715	COG1694	Mazg nucleotide pyrophosphohydrolase
PAN99_RS10720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAN99_RS10725	COG2140	Oxalate decarboxylase
PAN99_RS10735	COG4347	Protein of unknown function (DUF1405)
PAN99_RS10740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PAN99_RS10740	COG2010	Cytochrome c
PAN99_RS10745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PAN99_RS10750	COG0723	plastoquinol--plastocyanin reductase activity
PAN99_RS10765	COG0457	Tetratricopeptide repeat
PAN99_RS10775	COG0287	Prephenate dehydrogenase
PAN99_RS10810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PAN99_RS10815	COG4401	Chorismate mutase type I
PAN99_RS10830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PAN99_RS10835	COG0105	UTP biosynthetic process
PAN99_RS10840	COG0142	geranyltranstransferase activity
PAN99_RS10850	COG0142	geranyltranstransferase activity
PAN99_RS10865	COG0776	regulation of translation
PAN99_RS10870	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PAN99_RS10910	COG0539	negative regulation of cytoplasmic translation
PAN99_RS10925	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PAN99_RS10930	COG2959	enzyme of heme biosynthesis
PAN99_RS10935	COG3409	Peptidoglycan-binding domain 1 protein
PAN99_RS10935	COG3773	Cell wall hydrolase
PAN99_RS10940	COG2339	peptidase activity
PAN99_RS10945	COG0492	ferredoxin-NADP+ reductase activity
PAN99_RS10950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PAN99_RS10955	COG4862	establishment of competence for transformation
PAN99_RS10960	COG1408	metallophosphoesterase
PAN99_RS10970	COG1388	LysM domain
PAN99_RS10975	COG1266	CAAX protease self-immunity
PAN99_RS10980	COG0514	ATP-dependent DNA helicase (RecQ)
PAN99_RS10985	COG4955	Helix-turn-helix domain
PAN99_RS10990	COG1141	Ferredoxin
PAN99_RS10995	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PAN99_RS11000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PAN99_RS11010	COG1595	DNA-templated transcription, initiation
PAN99_RS11015	COG5002	protein histidine kinase activity
PAN99_RS11020	COG0745	RESPONSE REGULATOR receiver
PAN99_RS11025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PAN99_RS11030	COG1333	cytochrome c biogenesis protein
PAN99_RS11035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PAN99_RS11040	COG1187	pseudouridine synthase activity
PAN99_RS11045	COG0700	Nucleoside recognition
PAN99_RS11050	COG2715	membrane protein required for spore maturation
PAN99_RS11055	COG1686	Belongs to the peptidase S11 family
PAN99_RS11080	COG1547	Domain of unknown function (DUF309)
PAN99_RS11085	COG0456	acetyltransferase
PAN99_RS11100	COG0307	riboflavin synthase, alpha
PAN99_RS11105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PAN99_RS11105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PAN99_RS11115	COG0681	Belongs to the peptidase S26 family
PAN99_RS11125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PAN99_RS11130	COG4086	secreted protein
PAN99_RS11135	COG0019	diaminopimelate decarboxylase activity
PAN99_RS11140	COG0697	spore germination
PAN99_RS11155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAN99_RS11175	COG1191	sigma factor activity
PAN99_RS11185	COG1366	Belongs to the anti-sigma-factor antagonist family
PAN99_RS11190	COG1686	Belongs to the peptidase S11 family
PAN99_RS11195	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PAN99_RS11200	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PAN99_RS11205	COG4974	Belongs to the 'phage' integrase family
PAN99_RS11215	COG0735	belongs to the Fur family
PAN99_RS11220	COG1300	Membrane
PAN99_RS11235	COG0281	malic enzyme
PAN99_RS11240	COG1757	Na H antiporter
PAN99_RS11245	COG1027	Aspartate ammonia-lyase
PAN99_RS11250	COG0252	asparaginase activity
PAN99_RS11255	COG1396	sequence-specific DNA binding
PAN99_RS11260	COG1379	DNA repair
PAN99_RS11265	COG0494	nUDIX hydrolase
PAN99_RS11275	COG0667	Aldo Keto reductase
PAN99_RS11285	COG1073	alpha beta
PAN99_RS11295	COG4918	Iron-sulphur cluster biosynthesis
PAN99_RS11300	COG0456	acetyltransferase
PAN99_RS11300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PAN99_RS11305	COG2329	Antibiotic biosynthesis monooxygenase
PAN99_RS11310	COG0456	acetyltransferase
PAN99_RS11315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PAN99_RS11330	COG0628	permease
PAN99_RS11340	COG0346	lactoylglutathione lyase activity
PAN99_RS11350	COG3048	D-serine ammonia-lyase activity
PAN99_RS11355	COG0300	oxidoreductase activity
PAN99_RS11360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAN99_RS11365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAN99_RS11370	COG1024	Enoyl-CoA hydratase
PAN99_RS11375	COG3425	synthase
PAN99_RS11380	COG2124	cytochrome p450
PAN99_RS11385	COG3321	synthase
PAN99_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS11385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS11385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAN99_RS11385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS11390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS11390	COG3321	synthase
PAN99_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS11390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS11390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAN99_RS11395	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS11395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS11395	COG3321	synthase
PAN99_RS11395	COG0300	oxidoreductase activity
PAN99_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS11400	COG3321	synthase
PAN99_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS11400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS11400	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS11400	COG0300	oxidoreductase activity
PAN99_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS11405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS11405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAN99_RS11405	COG3321	synthase
PAN99_RS11405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS11410	COG0300	oxidoreductase activity
PAN99_RS11410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS11410	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS11410	COG3321	synthase
PAN99_RS11410	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS11415	COG3321	synthase
PAN99_RS11415	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS11415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS11415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAN99_RS11415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAN99_RS11420	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS11425	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS11440	COG2070	2-Nitropropane dioxygenase
PAN99_RS11440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PAN99_RS11445	COG0250	Participates in transcription elongation, termination and antitermination
PAN99_RS11465	COG0596	Alpha beta hydrolase
PAN99_RS11480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PAN99_RS11485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PAN99_RS11500	COG0706	membrane insertase activity
PAN99_RS11505	COG2195	Cleaves the N-terminal amino acid of tripeptides
PAN99_RS11510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PAN99_RS11515	COG0346	lactoylglutathione lyase activity
PAN99_RS11525	COG1376	ErfK ybiS ycfS ynhG family protein
PAN99_RS11530	COG4129	membrane
PAN99_RS11535	COG1126	abc transporter atp-binding protein
PAN99_RS11540	COG0765	amino acid transport
PAN99_RS11545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAN99_RS11555	COG1597	lipid kinase activity
PAN99_RS11560	COG0508	dehydrogenase complex catalyzes the overall conversion of
PAN99_RS11565	COG0022	dehydrogenase e1 component
PAN99_RS11570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PAN99_RS11575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PAN99_RS11580	COG3426	butyrate kinase activity
PAN99_RS11585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PAN99_RS11590	COG0280	phosphate acetyltransferase
PAN99_RS11595	COG3290	protein histidine kinase activity
PAN99_RS11595	COG3829	transcription factor binding
PAN99_RS11605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PAN99_RS11610	COG2079	MmgE PrpD family protein
PAN99_RS11615	COG0372	Belongs to the citrate synthase family
PAN99_RS11620	COG1960	acyl-CoA dehydrogenase activity
PAN99_RS11625	COG1250	3-hydroxyacyl-CoA dehydrogenase
PAN99_RS11630	COG0183	Belongs to the thiolase family
PAN99_RS11635	COG0584	glycerophosphoryl diester phosphodiesterase
PAN99_RS11640	COG0860	N-Acetylmuramoyl-L-alanine amidase
PAN99_RS11665	COG1902	pentaerythritol trinitrate reductase activity
PAN99_RS11680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PAN99_RS11685	COG0745	RESPONSE REGULATOR receiver
PAN99_RS11690	COG0750	zinc metalloprotease
PAN99_RS11695	COG0497	DNA recombination
PAN99_RS11705	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
PAN99_RS11715	COG0142	geranyltranstransferase activity
PAN99_RS11725	COG1570	exodeoxyribonuclease VII activity
PAN99_RS11740	COG1302	Protein conserved in bacteria
PAN99_RS11745	COG0439	Biotin carboxylase
PAN99_RS11750	COG0511	ligase activity, forming carbon-carbon bonds
PAN99_RS11790	COG3854	ATPases associated with a variety of cellular activities
PAN99_RS11805	COG0006	proline dipeptidase activity
PAN99_RS11815	COG3872	metal-dependent enzyme
PAN99_RS11825	COG1752	Esterase of the alpha-beta hydrolase superfamily
PAN99_RS11840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PAN99_RS11860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PAN99_RS11875	COG1396	sequence-specific DNA binding
PAN99_RS11885	COG0681	Belongs to the peptidase S26 family
PAN99_RS11910	COG4940	Competence protein ComGF
PAN99_RS11920	COG4970	Tfp pilus assembly protein FimT
PAN99_RS11925	COG4537	Required for transformation and DNA binding
PAN99_RS11930	COG1459	type II secretion system
PAN99_RS11935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PAN99_RS11940	COG0598	Magnesium transport protein CorA
PAN99_RS11945	COG1253	flavin adenine dinucleotide binding
PAN99_RS11950	COG1366	Belongs to the anti-sigma-factor antagonist family
PAN99_RS11960	COG1393	Belongs to the ArsC family
PAN99_RS11970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAN99_RS11980	COG0011	TIGRFAM Protein of
PAN99_RS11990	COG2866	Carboxypeptidase
PAN99_RS11995	COG1940	carbohydrate kinase activity
PAN99_RS12000	COG4483	Protein conserved in bacteria
PAN99_RS12005	COG1757	Na H antiporter
PAN99_RS12015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PAN99_RS12030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PAN99_RS12035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PAN99_RS12040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PAN99_RS12045	COG0581	inorganic phosphate transmembrane transporter activity
PAN99_RS12050	COG0573	inorganic phosphate transmembrane transporter activity
PAN99_RS12055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PAN99_RS12060	COG0768	penicillin binding
PAN99_RS12065	COG0477	Major facilitator Superfamily
PAN99_RS12070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PAN99_RS12075	COG2839	Protein conserved in bacteria
PAN99_RS12080	COG5521	maltodextrose utilization protein MalA
PAN99_RS12085	COG1388	LysM domain
PAN99_RS12095	COG4709	membrane
PAN99_RS12100	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
PAN99_RS12105	COG0735	belongs to the Fur family
PAN99_RS12110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAN99_RS12125	COG0513	Belongs to the DEAD box helicase family
PAN99_RS12140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PAN99_RS12145	COG2384	SAM-dependent methyltransferase
PAN99_RS12150	COG2010	Cytochrome c
PAN99_RS12155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAN99_RS12160	COG0358	DNA primase activity
PAN99_RS12175	COG0517	IMP dehydrogenase activity
PAN99_RS12180	COG0751	glycine-tRNA ligase activity
PAN99_RS12200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PAN99_RS12205	COG0295	cytidine deaminase activity
PAN99_RS12210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PAN99_RS12220	COG1480	7TM receptor with intracellular HD hydrolase
PAN99_RS12225	COG1702	phosphate starvation-inducible protein PhoH
PAN99_RS12230	COG0561	phosphatase activity
PAN99_RS12245	COG4864	UPF0365 protein
PAN99_RS12250	COG1030	water channel activity
PAN99_RS12255	COG1610	YqeY-like protein
PAN99_RS12265	COG1283	sodium-dependent phosphate transmembrane transporter activity
PAN99_RS12270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PAN99_RS12275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PAN99_RS12305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PAN99_RS12320	COG0860	N-Acetylmuramoyl-L-alanine amidase
PAN99_RS12350	COG0658	competence protein
PAN99_RS12350	COG2333	competence protein COMEC
PAN99_RS12355	COG2131	deaminase
PAN99_RS12360	COG1555	photosystem II stabilization
PAN99_RS12360	COG1596	polysaccharide export
PAN99_RS12365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAN99_RS12370	COG2226	methyltransferase
PAN99_RS12375	COG0799	negative regulation of ribosome biogenesis
PAN99_RS12380	COG1713	HD superfamily hydrolase involved in NAD metabolism
PAN99_RS12390	COG1534	Rna-binding protein
PAN99_RS12395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAN99_RS12400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PAN99_RS12405	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
PAN99_RS12420	COG2755	lipolytic protein G-D-S-L family
PAN99_RS12430	COG0398	Pfam SNARE associated Golgi protein
PAN99_RS12455	COG3708	Transcriptional regulator
PAN99_RS12455	COG2207	Transcriptional regulator
PAN99_RS12460	COG0563	adenylate kinase activity
PAN99_RS12470	COG2814	Major facilitator Superfamily
PAN99_RS12480	COG5444	nuclease activity
PAN99_RS12505	COG2318	DinB family
PAN99_RS12515	COG0561	phosphatase activity
PAN99_RS12520	COG0561	phosphatase activity
PAN99_RS12530	COG1482	cell wall glycoprotein biosynthetic process
PAN99_RS12535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PAN99_RS12535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PAN99_RS12535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PAN99_RS12540	COG3711	transcriptional antiterminator
PAN99_RS12540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PAN99_RS12550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PAN99_RS12555	COG0583	DNA-binding transcription factor activity
PAN99_RS12560	COG2814	Major facilitator Superfamily
PAN99_RS12565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PAN99_RS12565	COG2124	cytochrome p450
PAN99_RS12570	COG1309	transcriptional regulator
PAN99_RS12575	COG2226	methyltransferase
PAN99_RS12590	COG2116	formate transmembrane transporter activity
PAN99_RS12595	COG5609	conserved protein (DUF2294)
PAN99_RS12600	COG3383	formate dehydrogenase (NAD+) activity
PAN99_RS12605	COG2427	Protein of unknown function (DUF1641)
PAN99_RS12615	COG0626	cystathionine gamma-synthase activity
PAN99_RS12620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PAN99_RS12645	COG0768	penicillin binding
PAN99_RS12660	COG0826	peptidase U32
PAN99_RS12665	COG0826	peptidase U32
PAN99_RS12670	COG4122	O-methyltransferase activity
PAN99_RS12675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PAN99_RS12690	COG4472	Bacterial protein of unknown function (DUF965)
PAN99_RS12700	COG0628	permease
PAN99_RS12705	COG1126	abc transporter atp-binding protein
PAN99_RS12710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAN99_RS12715	COG0765	amino acid transport
PAN99_RS12720	COG0765	amino acid transport
PAN99_RS12735	COG3881	PFAM PRC-barrel domain
PAN99_RS12740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PAN99_RS12745	COG0457	Tetratricopeptide repeat
PAN99_RS12755	COG1104	cysteine desulfurase activity
PAN99_RS12760	COG1959	2 iron, 2 sulfur cluster binding
PAN99_RS12765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PAN99_RS12770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PAN99_RS12795	COG3103	Sh3 type 3 domain protein
PAN99_RS12795	COG4991	sh3 domain protein
PAN99_RS12795	COG0860	N-Acetylmuramoyl-L-alanine amidase
PAN99_RS12805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PAN99_RS12815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PAN99_RS12815	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PAN99_RS12820	COG5416	Lipopolysaccharide assembly protein A domain
PAN99_RS12825	COG0490	domain, Protein
PAN99_RS12830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PAN99_RS12830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PAN99_RS12840	COG2244	polysaccharide biosynthetic process
PAN99_RS12845	COG2323	membrane
PAN99_RS12855	COG1862	Preprotein translocase
PAN99_RS12895	COG1388	LysM domain
PAN99_RS12905	COG0157	Belongs to the NadC ModD family
PAN99_RS12910	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PAN99_RS12915	COG1104	cysteine desulfurase activity
PAN99_RS12920	COG1827	regulation of RNA biosynthetic process
PAN99_RS12925	COG0077	Prephenate dehydratase
PAN99_RS12940	COG3290	protein histidine kinase activity
PAN99_RS12945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PAN99_RS12950	COG2868	ribosomal protein
PAN99_RS12960	COG1994	Peptidase M50
PAN99_RS12965	COG0739	heme binding
PAN99_RS12970	COG2894	cell division
PAN99_RS12980	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PAN99_RS12990	COG1077	Cell shape determining protein MreB Mrl
PAN99_RS13010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PAN99_RS13015	COG0285	dihydrofolate synthase activity
PAN99_RS13020	COG0525	valine-tRNA ligase activity
PAN99_RS13030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PAN99_RS13035	COG1388	LysM domain
PAN99_RS13045	COG0113	porphobilinogen synthase activity
PAN99_RS13050	COG1587	Uroporphyrinogen-III synthase
PAN99_RS13060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PAN99_RS13080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PAN99_RS13085	COG0470	DNA polymerase III
PAN99_RS13085	COG1067	ATP-dependent peptidase activity
PAN99_RS13100	COG0457	Tetratricopeptide repeat
PAN99_RS13100	COG1477	protein flavinylation
PAN99_RS13115	COG0473	3-isopropylmalate dehydrogenase activity
PAN99_RS13130	COG0440	acetolactate synthase activity
PAN99_RS13135	COG0028	Belongs to the TPP enzyme family
PAN99_RS13165	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
PAN99_RS13185	COG0622	Phosphoesterase
PAN99_RS13190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PAN99_RS13200	COG5401	PFAM Sporulation and spore germination
PAN99_RS13210	COG1846	Transcriptional regulator
PAN99_RS13215	COG2197	response regulator
PAN99_RS13220	COG0824	Thioesterase
PAN99_RS13225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PAN99_RS13230	COG1053	succinate dehydrogenase
PAN99_RS13235	COG2009	succinate dehydrogenase
PAN99_RS13240	COG1719	4-vinyl reductase, 4VR
PAN99_RS13245	COG0527	aspartate kinase activity
PAN99_RS13255	COG3118	belongs to the thioredoxin family
PAN99_RS13260	COG3534	alpha-L-arabinofuranosidase
PAN99_RS13265	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PAN99_RS13270	COG2086	electron transfer activity
PAN99_RS13275	COG1024	Enoyl-CoA hydratase
PAN99_RS13280	COG1309	transcriptional regulator
PAN99_RS13285	COG0318	PFAM AMP-dependent synthetase and ligase
PAN99_RS13300	COG3766	membrane
PAN99_RS13310	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PAN99_RS13310	COG1796	DNA polymerase
PAN99_RS13315	COG1286	toxin biosynthetic process
PAN99_RS13330	COG0072	phenylalanine-tRNA ligase activity
PAN99_RS13330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAN99_RS13335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PAN99_RS13340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAN99_RS13350	COG3835	regulator
PAN99_RS13355	COG0277	FAD linked oxidase domain protein
PAN99_RS13360	COG0247	lactate metabolic process
PAN99_RS13365	COG1966	Carbon starvation protein
PAN99_RS13370	COG3534	alpha-L-arabinofuranosidase
PAN99_RS13375	COG0395	ABC-type sugar transport system, permease component
PAN99_RS13380	COG1175	transmembrane transport
PAN99_RS13385	COG1653	transport
PAN99_RS13395	COG0647	UMP catabolic process
PAN99_RS13400	COG0235	Class ii aldolase
PAN99_RS13405	COG1069	ribulokinase activity
PAN99_RS13410	COG2160	L-arabinose isomerase activity
PAN99_RS13415	COG3507	Belongs to the glycosyl hydrolase 43 family
PAN99_RS13420	COG1363	Peptidase, m42
PAN99_RS13430	COG3326	Membrane
PAN99_RS13435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PAN99_RS13445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PAN99_RS13450	COG1346	cytolysis
PAN99_RS13455	COG1380	Effector of murein hydrolase LrgA
PAN99_RS13460	COG3279	Response regulator of the LytR AlgR family
PAN99_RS13465	COG3275	phosphorelay sensor kinase activity
PAN99_RS13470	COG1011	Hydrolase
PAN99_RS13485	COG0398	Pfam SNARE associated Golgi protein
PAN99_RS13490	COG1484	DNA-dependent DNA replication
PAN99_RS13495	COG3611	Membrane attachment protein
PAN99_RS13510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PAN99_RS13515	COG1733	regulation of RNA biosynthetic process
PAN99_RS13520	COG2814	Major facilitator Superfamily
PAN99_RS13525	COG0656	L-ascorbic acid biosynthetic process
PAN99_RS13530	COG0237	dephospho-CoA kinase activity
PAN99_RS13535	COG1971	Probably functions as a manganese efflux pump
PAN99_RS13540	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PAN99_RS13545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PAN99_RS13545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PAN99_RS13550	COG5002	protein histidine kinase activity
PAN99_RS13555	COG0745	RESPONSE REGULATOR receiver
PAN99_RS13565	COG0538	isocitrate dehydrogenase activity
PAN99_RS13570	COG0372	Belongs to the citrate synthase family
PAN99_RS13590	COG0628	permease
PAN99_RS13595	COG3030	protein affecting phage T7 exclusion by the F plasmid
PAN99_RS13600	COG0469	pyruvate kinase activity
PAN99_RS13620	COG0281	malic enzyme
PAN99_RS13625	COG0587	DNA-directed DNA polymerase activity
PAN99_RS13645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PAN99_RS13655	COG4109	DRTGG domain
PAN99_RS13665	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS13685	COG0521	Mo-molybdopterin cofactor biosynthetic process
PAN99_RS13695	COG0827	DNA restriction-modification system
PAN99_RS13700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PAN99_RS13705	COG3874	Sporulation protein YtfJ
PAN99_RS13715	COG1714	RDD family
PAN99_RS13720	COG0616	signal peptide processing
PAN99_RS13725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PAN99_RS13730	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PAN99_RS13735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PAN99_RS13750	COG1104	cysteine desulfurase activity
PAN99_RS13755	COG1114	Component of the transport system for branched-chain amino acids
PAN99_RS13765	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PAN99_RS13770	COG1309	transcriptional regulator
PAN99_RS13775	COG1956	GAF domain-containing protein
PAN99_RS13780	COG2199	diguanylate cyclase activity
PAN99_RS13780	COG2203	Gaf domain
PAN99_RS13790	COG1012	belongs to the aldehyde dehydrogenase family
PAN99_RS13795	COG4282	regulation of fungal-type cell wall biogenesis
PAN99_RS13800	COG1017	nitric oxide dioxygenase activity
PAN99_RS13800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PAN99_RS13810	COG0693	protein deglycase activity
PAN99_RS13830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAN99_RS13835	COG1378	Sugar-specific transcriptional regulator TrmB
PAN99_RS13855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PAN99_RS13860	COG0454	-acetyltransferase
PAN99_RS13865	COG0517	IMP dehydrogenase activity
PAN99_RS13870	COG0123	including yeast histone deacetylase and acetoin utilization protein
PAN99_RS13875	COG1360	Flagellar Motor Protein
PAN99_RS13880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PAN99_RS13885	COG1609	Transcriptional regulator
PAN99_RS13890	COG1605	Chorismate mutase
PAN99_RS13890	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PAN99_RS13895	COG3118	belongs to the thioredoxin family
PAN99_RS13900	COG4980	gas vesicle protein
PAN99_RS13905	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PAN99_RS13915	COG1674	ftsk spoiiie
PAN99_RS13920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAN99_RS13930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PAN99_RS13940	COG1363	Peptidase, m42
PAN99_RS13945	COG5584	Small secreted protein
PAN99_RS13950	COG0281	malic enzyme
PAN99_RS13955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAN99_RS13970	COG0510	thiamine kinase activity
PAN99_RS13975	COG1597	lipid kinase activity
PAN99_RS13985	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PAN99_RS13990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PAN99_RS13995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PAN99_RS14000	COG2252	PERMEase
PAN99_RS14005	COG4473	ABC transporter
PAN99_RS14010	COG1131	(ABC) transporter
PAN99_RS14015	COG1349	DNA-binding transcription factor activity
PAN99_RS14020	COG1187	pseudouridine synthase activity
PAN99_RS14025	COG2244	polysaccharide biosynthetic process
PAN99_RS14030	COG2081	HI0933 family
PAN99_RS14035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PAN99_RS14045	COG1609	Transcriptional regulator
PAN99_RS14050	COG1653	transport
PAN99_RS14055	COG1175	transmembrane transport
PAN99_RS14060	COG0395	ABC-type sugar transport system, permease component
PAN99_RS14065	COG1486	melibiose metabolic process
PAN99_RS14075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PAN99_RS14090	COG2202	Pas domain
PAN99_RS14090	COG1366	Belongs to the anti-sigma-factor antagonist family
PAN99_RS14095	COG2814	Major facilitator Superfamily
PAN99_RS14100	COG5522	Integral membrane protein (intg_mem_TP0381)
PAN99_RS14105	COG0577	efflux transmembrane transporter activity
PAN99_RS14110	COG1136	(ABC) transporter
PAN99_RS14115	COG2205	protein histidine kinase activity
PAN99_RS14120	COG0745	RESPONSE REGULATOR receiver
PAN99_RS14125	COG0577	efflux transmembrane transporter activity
PAN99_RS14130	COG1136	(ABC) transporter
PAN99_RS14150	COG1131	(ABC) transporter
PAN99_RS14155	COG1725	Transcriptional regulator
PAN99_RS14175	COG0640	Transcriptional regulator
PAN99_RS14200	COG0477	Major facilitator Superfamily
PAN99_RS14205	COG1242	4 iron, 4 sulfur cluster binding
PAN99_RS14210	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PAN99_RS14220	COG0584	glycerophosphoryl diester phosphodiesterase
PAN99_RS14230	COG2267	carboxylic ester hydrolase activity
PAN99_RS14235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PAN99_RS14240	COG1113	amino acid transport
PAN99_RS14245	COG0367	asparagine synthase
PAN99_RS14265	COG1506	peptidase
PAN99_RS14270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PAN99_RS14275	COG1116	anion transmembrane transporter activity
PAN99_RS14280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PAN99_RS14285	COG0494	nUDIX hydrolase
PAN99_RS14290	COG4824	toxin secretion phage lysis holin
PAN99_RS14295	COG0783	Belongs to the Dps family
PAN99_RS14320	COG0288	reversible hydration of carbon dioxide
PAN99_RS14330	COG1271	oxidase subunit
PAN99_RS14335	COG1294	oxidase, subunit
PAN99_RS14345	COG4948	Mandelate Racemase Muconate Lactonizing
PAN99_RS14355	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PAN99_RS14360	COG0596	Alpha beta hydrolase
PAN99_RS14370	COG1169	isochorismate synthase
PAN99_RS14375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PAN99_RS14380	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
PAN99_RS14505	COG3859	Proton-coupled thiamine transporter YuaJ
PAN99_RS14510	COG2268	Band 7 protein
PAN99_RS14515	COG1585	Membrane protein implicated in regulation of membrane protease activity
PAN99_RS14520	COG2318	DinB family
PAN99_RS14530	COG1454	alcohol dehydrogenase
PAN99_RS14535	COG1012	belongs to the aldehyde dehydrogenase family
PAN99_RS14540	COG1510	regulation of RNA biosynthetic process
PAN99_RS14550	COG0569	domain protein
PAN99_RS14555	COG1705	Flagellar rod assembly protein muramidase FlgJ
PAN99_RS14560	COG1017	nitric oxide dioxygenase activity
PAN99_RS14560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PAN99_RS14580	COG0457	Tetratricopeptide repeat
PAN99_RS14610	COG0628	permease
PAN99_RS14615	COG0673	inositol 2-dehydrogenase activity
PAN99_RS14620	COG0693	protein deglycase activity
PAN99_RS14625	COG0840	transmembrane signaling receptor activity
PAN99_RS14630	COG0840	transmembrane signaling receptor activity
PAN99_RS14635	COG0840	transmembrane signaling receptor activity
PAN99_RS14640	COG0840	transmembrane signaling receptor activity
PAN99_RS14655	COG2070	2-Nitropropane dioxygenase
PAN99_RS14660	COG0432	Pfam Uncharacterised protein family UPF0047
PAN99_RS14665	COG0366	Alpha amylase catalytic
PAN99_RS14670	COG1253	flavin adenine dinucleotide binding
PAN99_RS14675	COG2738	Putative neutral zinc metallopeptidase
PAN99_RS14690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PAN99_RS14720	COG1335	isochorismatase
PAN99_RS14725	COG1979	alcohol dehydrogenase
PAN99_RS14730	COG1979	alcohol dehydrogenase
PAN99_RS14735	COG2155	Conserved Protein
PAN99_RS14740	COG1098	S1 RNA binding domain
PAN99_RS14745	COG0436	Aminotransferase
PAN99_RS14750	COG1522	sequence-specific DNA binding
PAN99_RS14755	COG2267	carboxylic ester hydrolase activity
PAN99_RS14765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PAN99_RS14770	COG2205	protein histidine kinase activity
PAN99_RS14780	COG5018	Exonuclease
PAN99_RS14785	COG2814	Major facilitator Superfamily
PAN99_RS14790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PAN99_RS14795	COG3011	Protein conserved in bacteria
PAN99_RS14805	COG3290	protein histidine kinase activity
PAN99_RS14810	COG4565	transcriptional regulatory protein
PAN99_RS14815	COG1744	ABC transporter substrate-binding protein PnrA-like
PAN99_RS14820	COG3845	ABC transporter
PAN99_RS14825	COG4603	Belongs to the binding-protein-dependent transport system permease family
PAN99_RS14830	COG1079	Belongs to the binding-protein-dependent transport system permease family
PAN99_RS14840	COG2111	Na H antiporter
PAN99_RS14840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PAN99_RS14845	COG2111	Na H antiporter
PAN99_RS14850	COG1006	Multisubunit Na H antiporter MnhC subunit
PAN99_RS14855	COG0651	ATP synthesis coupled electron transport
PAN99_RS14860	COG1863	multisubunit Na H antiporter MnhE subunit
PAN99_RS14865	COG2212	antiporter activity
PAN99_RS14870	COG1320	monovalent cation:proton antiporter activity
PAN99_RS14875	COG2050	protein possibly involved in aromatic compounds catabolism
PAN99_RS14880	COG2197	response regulator
PAN99_RS14885	COG4585	Histidine kinase
PAN99_RS14895	COG0142	geranyltranstransferase activity
PAN99_RS14910	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PAN99_RS14915	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PAN99_RS14920	COG1335	isochorismatase
PAN99_RS14925	COG5506	Protein of unknown function (DUF1694)
PAN99_RS14940	COG0628	permease
PAN99_RS14950	COG1418	mRNA catabolic process
PAN99_RS14955	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS14965	COG1511	domain protein
PAN99_RS14970	COG0433	COG0433 Predicted ATPase
PAN99_RS14970	COG1674	ftsk spoiiie
PAN99_RS14975	COG4499	WXG100 protein secretion system (Wss), protein YukC
PAN99_RS14980	COG5417	Belongs to the EsaB family
PAN99_RS14985	COG4842	Belongs to the WXG100 family
PAN99_RS14990	COG2508	Transcriptional regulator
PAN99_RS14990	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PAN99_RS14995	COG0686	Belongs to the AlaDH PNT family
PAN99_RS15000	COG5634	Uncharacterized conserved protein (DUF2278)
PAN99_RS15005	COG3251	PFAM MbtH domain protein
PAN99_RS15010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAN99_RS15015	COG3433	isochorismatase activity
PAN99_RS15015	COG1535	isochorismatase
PAN99_RS15020	COG1021	2,3-dihydroxybenzoate-AMP ligase
PAN99_RS15025	COG1169	isochorismate synthase
PAN99_RS15030	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS15035	COG2819	hydrolase of the alpha beta superfamily
PAN99_RS15040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PAN99_RS15045	COG1268	BioY protein
PAN99_RS15050	COG2056	Na+-H+ antiporter family
PAN99_RS15060	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
PAN99_RS15065	COG3584	3D domain protein
PAN99_RS15080	COG1252	NADH dehydrogenase
PAN99_RS15110	COG1131	(ABC) transporter
PAN99_RS15135	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAN99_RS15140	COG0316	Belongs to the HesB IscA family
PAN99_RS15150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PAN99_RS15160	COG1252	NADH dehydrogenase
PAN99_RS15165	COG4837	Protein of unknown function (DUF1462)
PAN99_RS15170	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PAN99_RS15175	COG0823	Involved in the tonB-independent uptake of proteins
PAN99_RS15175	COG1506	peptidase
PAN99_RS15175	COG4946	Tricorn protease homolog
PAN99_RS15185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PAN99_RS15190	COG0460	homoserine dehydrogenase
PAN99_RS15195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PAN99_RS15200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PAN99_RS15205	COG0647	UMP catabolic process
PAN99_RS15210	COG2445	Protein of unknown function DUF86
PAN99_RS15215	COG4470	Protein conserved in bacteria
PAN99_RS15225	COG0739	heme binding
PAN99_RS15235	COG0737	Belongs to the 5'-nucleotidase family
PAN99_RS15240	COG0730	response to heat
PAN99_RS15245	COG1801	Protein of unknown function DUF72
PAN99_RS15260	COG2508	Transcriptional regulator
PAN99_RS15285	COG2814	Major facilitator Superfamily
PAN99_RS15290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PAN99_RS15295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PAN99_RS15300	COG2356	endonuclease I
PAN99_RS15305	COG3842	ATPase activity
PAN99_RS15310	COG2188	Transcriptional regulator
PAN99_RS15315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAN99_RS15320	COG0395	ABC-type sugar transport system, permease component
PAN99_RS15325	COG1175	transmembrane transport
PAN99_RS15330	COG1653	transport
PAN99_RS15335	COG2222	sugar isomerase
PAN99_RS15340	COG0789	Transcriptional regulator
PAN99_RS15350	COG0322	excinuclease ABC activity
PAN99_RS15355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAN99_RS15365	COG3409	Peptidoglycan-binding domain 1 protein
PAN99_RS15380	COG5632	N-Acetylmuramoyl-L-alanine amidase
PAN99_RS15385	COG4824	toxin secretion phage lysis holin
PAN99_RS15405	COG5434	Belongs to the glycosyl hydrolase 28 family
PAN99_RS15420	COG3953	SLT domain
PAN99_RS15420	COG5412	phage tail tape measure protein
PAN99_RS15500	COG1674	ftsk spoiiie
PAN99_RS15500	COG4980	gas vesicle protein
PAN99_RS15505	COG0582	viral genome integration into host DNA
PAN99_RS15510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PAN99_RS15610	COG1396	sequence-specific DNA binding
PAN99_RS15610	COG3800	Transcriptional regulator
PAN99_RS15630	COG0719	Fe-S assembly protein
PAN99_RS15635	COG0822	iron-sulfur transferase activity
PAN99_RS15640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PAN99_RS15645	COG0719	Fe-S assembly protein
PAN99_RS15650	COG0396	ATPase activity
PAN99_RS15660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PAN99_RS15665	COG1464	Belongs to the NlpA lipoprotein family
PAN99_RS15670	COG2011	ABC-type metal ion transport system permease component
PAN99_RS15675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PAN99_RS15685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PAN99_RS15690	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PAN99_RS15705	COG1393	Belongs to the ArsC family
PAN99_RS15710	COG1960	acyl-CoA dehydrogenase activity
PAN99_RS15715	COG0183	Belongs to the thiolase family
PAN99_RS15720	COG1024	Enoyl-CoA hydratase
PAN99_RS15720	COG1250	3-hydroxyacyl-CoA dehydrogenase
PAN99_RS15740	COG5577	PFAM Coat F domain
PAN99_RS15745	COG1846	Transcriptional regulator
PAN99_RS15750	COG0477	Major facilitator Superfamily
PAN99_RS15755	COG0583	DNA-binding transcription factor activity
PAN99_RS15775	COG1120	ATPase activity
PAN99_RS15790	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS15795	COG0783	Belongs to the Dps family
PAN99_RS15800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAN99_RS15805	COG0745	RESPONSE REGULATOR receiver
PAN99_RS15810	COG2205	protein histidine kinase activity
PAN99_RS15810	COG2770	Histidine kinase
PAN99_RS15820	COG1309	transcriptional regulator
PAN99_RS15825	COG0114	fumarate hydratase activity
PAN99_RS15835	COG0697	spore germination
PAN99_RS15840	COG0814	amino acid
PAN99_RS15850	COG2197	response regulator
PAN99_RS15855	COG4585	Histidine kinase
PAN99_RS15860	COG4758	membrane
PAN99_RS15865	COG3595	metallopeptidase activity
PAN99_RS15870	COG1842	Phage shock protein A
PAN99_RS15875	COG4758	membrane
PAN99_RS15880	COG2814	Major facilitator Superfamily
PAN99_RS15885	COG2096	Adenosyltransferase
PAN99_RS15890	COG1120	ATPase activity
PAN99_RS15895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAN99_RS15900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PAN99_RS15905	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS15910	COG3386	PFAM SMP-30 Gluconolaconase
PAN99_RS15915	COG2205	protein histidine kinase activity
PAN99_RS15920	COG0745	RESPONSE REGULATOR receiver
PAN99_RS15930	COG1191	sigma factor activity
PAN99_RS15940	COG2140	Oxalate decarboxylase
PAN99_RS15950	COG1120	ATPase activity
PAN99_RS15955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAN99_RS15960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAN99_RS15965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PAN99_RS15970	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PAN99_RS15975	COG0531	amino acid
PAN99_RS15985	COG1988	membrane-bound metal-dependent
PAN99_RS15990	COG1368	sulfuric ester hydrolase activity
PAN99_RS15995	COG1910	domain protein
PAN99_RS16000	COG0725	ABC transporter, periplasmic molybdate-binding protein
PAN99_RS16005	COG4149	molybdate abc transporter
PAN99_RS16010	COG2197	response regulator
PAN99_RS16015	COG3850	Histidine kinase
PAN99_RS16030	COG0842	Transport permease protein
PAN99_RS16035	COG0656	L-ascorbic acid biosynthetic process
PAN99_RS16055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PAN99_RS16060	COG3973	AAA domain
PAN99_RS16065	COG2860	membrane
PAN99_RS16075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PAN99_RS16080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PAN99_RS16085	COG2217	Heavy metal translocating P-type atpase
PAN99_RS16090	COG2217	Heavy metal translocating P-type atpase
PAN99_RS16095	COG2608	mercury ion transmembrane transporter activity
PAN99_RS16100	COG1937	Protein conserved in bacteria
PAN99_RS16105	COG0673	inositol 2-dehydrogenase activity
PAN99_RS16115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAN99_RS16120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PAN99_RS16125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAN99_RS16130	COG1126	abc transporter atp-binding protein
PAN99_RS16135	COG0765	amino acid transport
PAN99_RS16140	COG0765	amino acid transport
PAN99_RS16145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAN99_RS16150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAN99_RS16155	COG0454	-acetyltransferase
PAN99_RS16160	COG0583	DNA-binding transcription factor activity
PAN99_RS16165	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS16170	COG2732	(Barnase) inhibitor
PAN99_RS16185	COG0557	exoribonuclease II activity
PAN99_RS16190	COG1647	Serine aminopeptidase, S33
PAN99_RS16195	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PAN99_RS16200	COG1476	TRANSCRIPTIONal
PAN99_RS16205	COG1396	sequence-specific DNA binding
PAN99_RS16210	COG1396	sequence-specific DNA binding
PAN99_RS16215	COG1733	regulation of RNA biosynthetic process
PAN99_RS16240	COG1131	(ABC) transporter
PAN99_RS16245	COG1174	glycine betaine transport
PAN99_RS16250	COG1732	Glycine betaine
PAN99_RS16255	COG1174	glycine betaine transport
PAN99_RS16260	COG0517	IMP dehydrogenase activity
PAN99_RS16260	COG1125	glycine betaine transport
PAN99_RS16265	COG1510	regulation of RNA biosynthetic process
PAN99_RS16270	COG1174	glycine betaine transport
PAN99_RS16275	COG1732	Glycine betaine
PAN99_RS16280	COG1174	glycine betaine transport
PAN99_RS16285	COG1125	glycine betaine transport
PAN99_RS16285	COG0517	IMP dehydrogenase activity
PAN99_RS16290	COG1510	regulation of RNA biosynthetic process
PAN99_RS16295	COG2095	MarC family integral membrane protein
PAN99_RS16300	COG3064	Membrane
PAN99_RS16305	COG4640	response to antibiotic
PAN99_RS16310	COG0456	acetyltransferase
PAN99_RS16325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PAN99_RS16340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PAN99_RS16345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAN99_RS16350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PAN99_RS16360	COG2234	aminopeptidase activity
PAN99_RS16380	COG0126	phosphoglycerate kinase activity
PAN99_RS16385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PAN99_RS16390	COG2390	Transcriptional regulator
PAN99_RS16395	COG2814	Major facilitator Superfamily
PAN99_RS16400	COG1609	Transcriptional regulator
PAN99_RS16405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAN99_RS16415	COG0583	DNA-binding transcription factor activity
PAN99_RS16420	COG0697	spore germination
PAN99_RS16425	COG1113	amino acid transport
PAN99_RS16435	COG1737	Transcriptional regulator
PAN99_RS16440	COG1070	Carbohydrate kinase
PAN99_RS16465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PAN99_RS16470	COG2186	Transcriptional regulator
PAN99_RS16475	COG1620	l-lactate permease
PAN99_RS16480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PAN99_RS16490	COG5039	Polysaccharide pyruvyl transferase
PAN99_RS16495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PAN99_RS16500	COG0110	maltose O-acetyltransferase activity
PAN99_RS16505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PAN99_RS16510	COG2244	polysaccharide biosynthetic process
PAN99_RS16515	COG1216	Glycosyl transferase, family 2
PAN99_RS16520	COG5039	Polysaccharide pyruvyl transferase
PAN99_RS16525	COG1216	Glycosyl transferase, family 2
PAN99_RS16535	COG0438	transferase activity, transferring glycosyl groups
PAN99_RS16540	COG1215	transferase activity, transferring glycosyl groups
PAN99_RS16545	COG0438	transferase activity, transferring glycosyl groups
PAN99_RS16550	COG1086	Polysaccharide biosynthesis protein
PAN99_RS16555	COG0489	protein tyrosine kinase activity
PAN99_RS16560	COG3944	biosynthesis protein
PAN99_RS16565	COG1396	sequence-specific DNA binding
PAN99_RS16570	COG2272	Belongs to the type-B carboxylesterase lipase family
PAN99_RS16580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PAN99_RS16585	COG2364	Membrane
PAN99_RS16590	COG0456	acetyltransferase
PAN99_RS16595	COG3479	Phenolic acid decarboxylase
PAN99_RS16635	COG2223	nitrite transmembrane transporter activity
PAN99_RS16640	COG1609	Transcriptional regulator
PAN99_RS16650	COG0583	DNA-binding transcription factor activity
PAN99_RS16655	COG2828	Protein conserved in bacteria
PAN99_RS16660	COG2814	Major facilitator Superfamily
PAN99_RS16660	COG0477	Major facilitator Superfamily
PAN99_RS16665	COG1611	Belongs to the LOG family
PAN99_RS16670	COG1694	Mazg nucleotide pyrophosphohydrolase
PAN99_RS16675	COG0659	secondary active sulfate transmembrane transporter activity
PAN99_RS16680	COG0288	reversible hydration of carbon dioxide
PAN99_RS16685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAN99_RS16690	COG4290	ribonuclease
PAN99_RS16695	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PAN99_RS16700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PAN99_RS16710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PAN99_RS16720	COG1051	belongs to the nudix hydrolase family
PAN99_RS16725	COG0492	ferredoxin-NADP+ reductase activity
PAN99_RS16730	COG3883	PFAM NLP P60 protein
PAN99_RS16730	COG0791	NLP P60 protein
PAN99_RS16735	COG0457	Tetratricopeptide repeat
PAN99_RS16740	COG5002	protein histidine kinase activity
PAN99_RS16745	COG0745	RESPONSE REGULATOR receiver
PAN99_RS16755	COG1132	(ABC) transporter
PAN99_RS16760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PAN99_RS16760	COG0140	phosphoribosyl-ATP diphosphatase activity
PAN99_RS16785	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PAN99_RS16800	COG4990	cell redox homeostasis
PAN99_RS16805	COG0110	maltose O-acetyltransferase activity
PAN99_RS16825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PAN99_RS16835	COG2188	Transcriptional regulator
PAN99_RS16840	COG1309	transcriptional regulator
PAN99_RS16845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PAN99_RS16850	COG1950	PFAM Membrane protein of
PAN99_RS16855	COG1983	PspC domain protein
PAN99_RS16860	COG3595	metallopeptidase activity
PAN99_RS16875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PAN99_RS16885	COG4897	Protein conserved in bacteria
PAN99_RS16890	COG3848	Pyruvate phosphate dikinase
PAN99_RS16890	COG0574	Belongs to the PEP-utilizing enzyme family
PAN99_RS16895	COG1309	transcriptional regulator
PAN99_RS16900	COG2814	Major facilitator Superfamily
PAN99_RS16910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAN99_RS16920	COG3409	Peptidoglycan-binding domain 1 protein
PAN99_RS16920	COG0793	Belongs to the peptidase S41A family
PAN99_RS16925	COG3420	alginic acid biosynthetic process
PAN99_RS16930	COG2177	Part of the ABC transporter FtsEX involved in
PAN99_RS16935	COG2884	Cell division ATP-binding protein ftsE
PAN99_RS16940	COG2010	Cytochrome c
PAN99_RS16945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAN99_RS16960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PAN99_RS16975	COG1516	flagellar protein fliS
PAN99_RS16980	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PAN99_RS16985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PAN99_RS17005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PAN99_RS17010	COG1256	bacterial-type flagellum assembly
PAN99_RS17010	COG4786	Flagellar basal body rod
PAN99_RS17015	COG3418	PFAM FlgN family protein
PAN99_RS17020	COG2747	anti-sigma28 factor FlgM
PAN99_RS17030	COG1040	competence protein
PAN99_RS17040	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PAN99_RS17045	COG1307	EDD domain protein, DegV family
PAN99_RS17050	COG2197	response regulator
PAN99_RS17055	COG4585	Histidine kinase
PAN99_RS17060	COG1739	Uncharacterized protein family UPF0029
PAN99_RS17065	COG1316	TRANSCRIPTIONal
PAN99_RS17070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PAN99_RS17075	COG0438	transferase activity, transferring glycosyl groups
PAN99_RS17080	COG1215	transferase activity, transferring glycosyl groups
PAN99_RS17085	COG3206	protein involved in exopolysaccharide biosynthesis
PAN99_RS17090	COG3307	-O-antigen
PAN99_RS17095	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PAN99_RS17100	COG0438	transferase activity, transferring glycosyl groups
PAN99_RS17100	COG0297	glycogen (starch) synthase activity
PAN99_RS17105	COG2244	polysaccharide biosynthetic process
PAN99_RS17115	COG2247	cell wall binding repeat
PAN99_RS17115	COG0860	N-Acetylmuramoyl-L-alanine amidase
PAN99_RS17120	COG2385	sporulation resulting in formation of a cellular spore
PAN99_RS17120	COG2247	cell wall binding repeat
PAN99_RS17130	COG1316	TRANSCRIPTIONal
PAN99_RS17135	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PAN99_RS17140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PAN99_RS17145	COG1134	teichoic acid transport
PAN99_RS17150	COG1682	transport, permease protein
PAN99_RS17155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PAN99_RS17165	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PAN99_RS17170	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PAN99_RS17175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PAN99_RS17180	COG4193	domain, Protein
PAN99_RS17185	COG1482	cell wall glycoprotein biosynthetic process
PAN99_RS17190	COG0697	spore germination
PAN99_RS17195	COG0814	amino acid
PAN99_RS17205	COG1215	transferase activity, transferring glycosyl groups
PAN99_RS17210	COG2814	Major facilitator Superfamily
PAN99_RS17215	COG1316	TRANSCRIPTIONal
PAN99_RS17220	COG0561	phosphatase activity
PAN99_RS17225	COG2433	Pfam Transposase IS66
PAN99_RS17230	COG0791	NLP P60 protein
PAN99_RS17240	COG2843	Capsule synthesis protein
PAN99_RS17255	COG0697	spore germination
PAN99_RS17260	COG0814	amino acid
PAN99_RS17270	COG1609	Transcriptional regulator
PAN99_RS17275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAN99_RS17285	COG1129	ABC transporter
PAN99_RS17290	COG1172	Belongs to the binding-protein-dependent transport system permease family
PAN99_RS17295	COG1879	ABC-type sugar transport system periplasmic component
PAN99_RS17300	COG3103	Sh3 type 3 domain protein
PAN99_RS17305	COG2249	NAD(P)H dehydrogenase (quinone) activity
PAN99_RS17310	COG3527	Alpha-acetolactate decarboxylase
PAN99_RS17315	COG0028	Belongs to the TPP enzyme family
PAN99_RS17320	COG0583	DNA-binding transcription factor activity
PAN99_RS17325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PAN99_RS17340	COG5337	Spore coat protein CotH
PAN99_RS17350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PAN99_RS17360	COG0405	Gamma-glutamyltransferase
PAN99_RS17365	COG1522	sequence-specific DNA binding
PAN99_RS17370	COG2059	Chromate
PAN99_RS17375	COG2059	Chromate
PAN99_RS17385	COG0655	NAD(P)H dehydrogenase (quinone) activity
PAN99_RS17390	COG0583	DNA-binding transcription factor activity
PAN99_RS17430	COG5444	nuclease activity
PAN99_RS17445	COG3878	Protein conserved in bacteria
PAN99_RS17450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PAN99_RS17455	COG4464	protein tyrosine phosphatase activity
PAN99_RS17460	COG0489	protein tyrosine kinase activity
PAN99_RS17465	COG3944	biosynthesis protein
PAN99_RS17475	COG4715	Zinc finger, swim domain protein
PAN99_RS17480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PAN99_RS17485	COG0561	phosphatase activity
PAN99_RS17490	COG1349	DNA-binding transcription factor activity
PAN99_RS17495	COG0629	single-stranded DNA binding
PAN99_RS17520	COG0457	Tetratricopeptide repeat
PAN99_RS17525	COG4786	Flagellar basal body rod
PAN99_RS17530	COG4786	Flagellar basal body rod
PAN99_RS17535	COG1077	Cell shape determining protein MreB Mrl
PAN99_RS17540	COG1609	Transcriptional regulator
PAN99_RS17545	COG1846	Transcriptional regulator
PAN99_RS17550	COG2814	Major facilitator Superfamily
PAN99_RS17555	COG1953	Uracil, thiamine, allantoin
PAN99_RS17560	COG0477	Major facilitator Superfamily
PAN99_RS17565	COG1335	isochorismatase
PAN99_RS17570	COG0004	ammonium transporteR
PAN99_RS17575	COG0347	Belongs to the P(II) protein family
PAN99_RS17580	COG0772	Belongs to the SEDS family
PAN99_RS17585	COG0671	phosphoesterase, PA-phosphatase related
PAN99_RS17595	COG0739	heme binding
PAN99_RS17600	COG1247	-acetyltransferase
PAN99_RS17615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAN99_RS17625	COG0726	polysaccharide deacetylase
PAN99_RS17635	COG1959	2 iron, 2 sulfur cluster binding
PAN99_RS17650	COG0831	urea catabolic process
PAN99_RS17655	COG3237	CsbD-like
PAN99_RS17660	COG1994	Peptidase M50
PAN99_RS17665	COG0457	Tetratricopeptide repeat
PAN99_RS17675	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PAN99_RS17685	COG2304	oxidoreductase activity
PAN99_RS17690	COG2304	oxidoreductase activity
PAN99_RS17695	COG2385	sporulation resulting in formation of a cellular spore
PAN99_RS17700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAN99_RS17710	COG4836	Membrane
PAN99_RS17780	COG0698	ribose 5-phosphate isomerase
PAN99_RS17785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAN99_RS17795	COG0009	L-threonylcarbamoyladenylate synthase
PAN99_RS17800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PAN99_RS17820	COG2890	protein-(glutamine-N5) methyltransferase activity
PAN99_RS17825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PAN99_RS17830	COG0346	lactoylglutathione lyase activity
PAN99_RS17835	COG0789	Transcriptional regulator
PAN99_RS17840	COG0679	Auxin Efflux Carrier
PAN99_RS17845	COG0281	malic enzyme
PAN99_RS17860	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PAN99_RS17870	COG1494	fructose-1,6-bisphosphatase
PAN99_RS17875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAN99_RS17885	COG0191	fructose-bisphosphate aldolase activity
PAN99_RS17890	COG2204	response regulator
PAN99_RS17895	COG4821	SIS domain
PAN99_RS17910	COG2181	nitrate reductase activity
PAN99_RS17910	COG0247	lactate metabolic process
PAN99_RS17915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAN99_RS17930	COG1132	(ABC) transporter
PAN99_RS17935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAN99_RS17945	COG2181	nitrate reductase activity
PAN99_RS17950	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PAN99_RS17955	COG1140	nitrate reductase beta subunit
PAN99_RS17960	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAN99_RS17965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PAN99_RS17975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PAN99_RS17980	COG2223	nitrite transmembrane transporter activity
PAN99_RS17990	COG4506	Protein conserved in bacteria
PAN99_RS17995	COG0457	Tetratricopeptide repeat
PAN99_RS18030	COG0010	Belongs to the arginase family
PAN99_RS18035	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PAN99_RS18040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PAN99_RS18055	COG1994	Peptidase M50
PAN99_RS18060	COG1942	4-Oxalocrotonate Tautomerase
PAN99_RS18065	COG1846	Transcriptional regulator
PAN99_RS18070	COG0531	amino acid
PAN99_RS18075	COG3465	dGTPase activity
PAN99_RS18080	COG1078	dGTPase activity
PAN99_RS18095	COG1695	Transcriptional regulator
PAN99_RS18105	COG1131	(ABC) transporter
PAN99_RS18110	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PAN99_RS18140	COG0583	DNA-binding transcription factor activity
PAN99_RS18145	COG2855	membrane
PAN99_RS18150	COG0280	phosphate acetyltransferase
PAN99_RS18160	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS18165	COG0436	Aminotransferase
PAN99_RS18195	COG2814	Major facilitator Superfamily
PAN99_RS18200	COG2814	Major facilitator Superfamily
PAN99_RS18205	COG0833	amino acid
PAN99_RS18210	COG4187	Peptidase family M20/M25/M40
PAN99_RS18215	COG1012	belongs to the aldehyde dehydrogenase family
PAN99_RS18220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PAN99_RS18230	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
PAN99_RS18235	COG1091	dTDP-4-dehydrorhamnose reductase activity
PAN99_RS18240	COG1088	dTDP-glucose 4,6-dehydratase activity
PAN99_RS18245	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PAN99_RS18250	COG3980	spore coat polysaccharide biosynthesis protein
PAN99_RS18255	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
PAN99_RS18260	COG2089	acid synthase
PAN99_RS18265	COG0456	acetyltransferase
PAN99_RS18270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PAN99_RS18275	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PAN99_RS18280	COG0463	Glycosyl transferase, family 2
PAN99_RS18290	COG2363	Small membrane protein
PAN99_RS18295	COG2233	PERMEase
PAN99_RS18310	COG1216	Glycosyl transferase, family 2
PAN99_RS18325	COG1695	Transcriptional regulator
PAN99_RS18330	COG0351	phosphomethylpyrimidine kinase
PAN99_RS18340	COG1621	beta-fructofuranosidase activity
PAN99_RS18345	COG1263	PTS System
PAN99_RS18345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PAN99_RS18350	COG3711	transcriptional antiterminator
PAN99_RS18360	COG1404	Belongs to the peptidase S8 family
PAN99_RS18365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAN99_RS18370	COG0778	Nitroreductase
PAN99_RS18375	COG0772	Belongs to the SEDS family
PAN99_RS18380	COG0454	-acetyltransferase
PAN99_RS18400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PAN99_RS18405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PAN99_RS18410	COG2261	transglycosylase associated protein
PAN99_RS18415	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
PAN99_RS18425	COG2246	polysaccharide biosynthetic process
PAN99_RS18430	COG1309	transcriptional regulator
PAN99_RS18450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PAN99_RS18455	COG2837	iron assimilation
PAN99_RS18475	COG0583	DNA-binding transcription factor activity
PAN99_RS18485	COG1346	cytolysis
PAN99_RS18490	COG4895	conserved protein (DUF2196)
PAN99_RS18495	COG0789	Transcriptional regulator
PAN99_RS18500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PAN99_RS18505	COG0346	lactoylglutathione lyase activity
PAN99_RS18510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PAN99_RS18515	COG1404	Belongs to the peptidase S8 family
PAN99_RS18520	COG1442	glycosyl transferase family 8
PAN99_RS18525	COG1846	Transcriptional regulator
PAN99_RS18530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PAN99_RS18535	COG2357	RelA SpoT domain protein
PAN99_RS18540	COG1575	Belongs to the MenA family. Type 1 subfamily
PAN99_RS18555	COG1696	Membrane protein involved in D-alanine export
PAN99_RS18565	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PAN99_RS18570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PAN99_RS18575	COG1486	melibiose metabolic process
PAN99_RS18580	COG1447	Phosphotransferase system cellobiose-specific component IIA
PAN99_RS18585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PAN99_RS18590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PAN99_RS18595	COG3711	transcriptional antiterminator
PAN99_RS18595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PAN99_RS18610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAN99_RS18615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAN99_RS18625	COG0640	Transcriptional regulator
PAN99_RS18630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PAN99_RS18635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PAN99_RS18640	COG1447	Phosphotransferase system cellobiose-specific component IIA
PAN99_RS18645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PAN99_RS18650	COG2723	6-phospho-beta-galactosidase activity
PAN99_RS18655	COG1940	carbohydrate kinase activity
PAN99_RS18660	COG1482	cell wall glycoprotein biosynthetic process
PAN99_RS18670	COG0753	catalase activity
PAN99_RS18675	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
PAN99_RS18680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PAN99_RS18685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PAN99_RS18690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PAN99_RS18695	COG4988	ABC transporter
PAN99_RS18700	COG1294	oxidase, subunit
PAN99_RS18705	COG1271	oxidase subunit
PAN99_RS18710	COG3493	citrate carrier protein
PAN99_RS18715	COG0726	polysaccharide deacetylase
PAN99_RS18720	COG3842	ATPase activity
PAN99_RS18725	COG2508	Transcriptional regulator
PAN99_RS18730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAN99_RS18740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PAN99_RS18755	COG4894	glucomannan catabolic process
PAN99_RS18760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PAN99_RS18765	COG0500	methyltransferase
PAN99_RS18770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PAN99_RS18785	COG0753	catalase activity
PAN99_RS18785	COG0693	protein deglycase activity
PAN99_RS18790	COG2851	Citrate transporter
PAN99_RS18795	COG2273	Hydrolase Family 16
PAN99_RS18805	COG2270	Major facilitator Superfamily
PAN99_RS18810	COG0513	Belongs to the DEAD box helicase family
PAN99_RS18890	COG0697	spore germination
PAN99_RS18895	COG0589	response to stress
PAN99_RS18905	COG0494	nUDIX hydrolase
PAN99_RS18910	COG3507	Belongs to the glycosyl hydrolase 43 family
PAN99_RS18935	COG0010	Belongs to the arginase family
PAN99_RS18940	COG0833	amino acid
PAN99_RS18945	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PAN99_RS18950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PAN99_RS18960	COG2390	Transcriptional regulator
PAN99_RS18965	COG0561	phosphatase activity
PAN99_RS18995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PAN99_RS19000	COG5294	Protein conserved in bacteria
PAN99_RS19005	COG0577	efflux transmembrane transporter activity
PAN99_RS19010	COG1136	(ABC) transporter
PAN99_RS19015	COG2205	protein histidine kinase activity
PAN99_RS19020	COG0745	RESPONSE REGULATOR receiver
PAN99_RS19035	COG1082	Xylose isomerase domain protein TIM barrel
PAN99_RS19045	COG2814	Major facilitator Superfamily
PAN99_RS19075	COG1349	DNA-binding transcription factor activity
PAN99_RS19080	COG0667	Aldo Keto reductase
PAN99_RS19085	COG2814	Major facilitator Superfamily
PAN99_RS19100	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS19105	COG2197	response regulator
PAN99_RS19110	COG4585	Histidine kinase
PAN99_RS19115	COG3239	Fatty acid desaturase
PAN99_RS19120	COG1309	transcriptional regulator
PAN99_RS19125	COG1012	belongs to the aldehyde dehydrogenase family
PAN99_RS19130	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PAN99_RS19140	COG0640	Transcriptional regulator
PAN99_RS19145	COG2814	Major facilitator Superfamily
PAN99_RS19150	COG1714	RDD family
PAN99_RS19165	COG0501	Belongs to the peptidase M48B family
PAN99_RS19170	COG1715	Restriction endonuclease
PAN99_RS19175	COG0450	alkyl hydroperoxide reductase
PAN99_RS19180	COG3634	alkyl hydroperoxide reductase activity
PAN99_RS19185	COG1113	amino acid transport
PAN99_RS19195	COG2080	2 iron, 2 sulfur cluster binding
PAN99_RS19210	COG2068	MobA-Related Protein
PAN99_RS19215	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PAN99_RS19235	COG1192	Involved in chromosome partitioning
PAN99_RS19275	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PAN99_RS19280	COG0667	Aldo Keto reductase
PAN99_RS19285	COG0456	acetyltransferase
PAN99_RS19295	COG0457	Tetratricopeptide repeat
PAN99_RS19300	COG0010	Belongs to the arginase family
PAN99_RS19305	COG0833	amino acid
PAN99_RS19310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PAN99_RS19315	COG5658	integral membrane protein
PAN99_RS19320	COG0640	Transcriptional regulator
PAN99_RS19325	COG3829	transcription factor binding
PAN99_RS19335	COG0488	(ABC) transporter
PAN99_RS19350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PAN99_RS19355	COG5002	protein histidine kinase activity
PAN99_RS19365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAN99_RS19370	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PAN99_RS19375	COG4853	Protein conserved in bacteria
PAN99_RS19380	COG4863	YycH protein
PAN99_RS19385	COG5002	protein histidine kinase activity
PAN99_RS19390	COG0745	RESPONSE REGULATOR receiver
PAN99_RS19420	COG0346	lactoylglutathione lyase activity
PAN99_RS19425	COG0305	Participates in initiation and elongation during chromosome replication
PAN99_RS19440	COG3093	addiction module antidote protein HigA
PAN99_RS19445	COG0297	glycogen (starch) synthase activity
PAN99_RS19455	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PAN99_RS19460	COG0438	transferase activity, transferring glycosyl groups
PAN99_RS19480	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
PAN99_RS19485	COG4241	membrane
PAN99_RS19495	COG5577	PFAM Coat F domain
PAN99_RS19500	COG1733	regulation of RNA biosynthetic process
PAN99_RS19510	COG0697	spore germination
PAN99_RS19515	COG1621	beta-fructofuranosidase activity
PAN99_RS19520	COG1621	beta-fructofuranosidase activity
PAN99_RS19525	COG1802	Transcriptional regulator
PAN99_RS19530	COG2318	DinB family
PAN99_RS19535	COG2211	Major facilitator Superfamily
PAN99_RS19545	COG0778	Nitroreductase
PAN99_RS19550	COG1846	Transcriptional regulator
PAN99_RS19555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAN99_RS19560	COG1846	Transcriptional regulator
PAN99_RS19575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PAN99_RS19580	COG0583	DNA-binding transcription factor activity
PAN99_RS19585	COG1028	Short-chain dehydrogenase reductase Sdr
PAN99_RS19595	COG0697	spore germination
PAN99_RS19600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PAN99_RS19605	COG1959	2 iron, 2 sulfur cluster binding
PAN99_RS19610	COG1396	sequence-specific DNA binding
PAN99_RS19620	COG1331	Highly conserved protein containing a thioredoxin domain
PAN99_RS19625	COG1266	CAAX protease self-immunity
PAN99_RS19630	COG0477	Major facilitator Superfamily
PAN99_RS19630	COG2814	Major facilitator Superfamily
PAN99_RS19635	COG0346	lactoylglutathione lyase activity
PAN99_RS19640	COG1609	Transcriptional regulator
PAN99_RS19645	COG0708	Exodeoxyribonuclease III
PAN99_RS19650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PAN99_RS19655	COG2169	Transcriptional regulator
PAN99_RS19665	COG0629	single-stranded DNA binding
PAN99_RS19675	COG0012	GTP binding
PAN99_RS19680	COG0243	molybdopterin cofactor binding
PAN99_RS19685	COG4481	Protein conserved in bacteria
PAN99_RS19690	COG3949	Membrane
PAN99_RS19705	COG1475	DNA binding
PAN99_RS19710	COG1192	Involved in chromosome partitioning
PAN99_RS19735	COG1847	R3H domain protein
PAN99_RS19740	COG0706	membrane insertase activity
PAN99_RS19805	COG1525	nuclease
PAN99_RS19810	COG4282	regulation of fungal-type cell wall biogenesis
PAN99_RS19855	COG3391	amine dehydrogenase activity
PAN99_RS19865	COG0457	Tetratricopeptide repeat
PAN99_RS19870	COG1388	LysM domain