locus-tag	class	description
V753_RS00010	COG0592	DNA-directed DNA polymerase activity
V753_RS00015	COG2501	S4 domain
V753_RS00030	COG0187	DNA topoisomerase II activity
V753_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
V753_RS00070	COG0516	GMP reductase activity
V753_RS00070	COG0517	IMP dehydrogenase activity
V753_RS00075	COG1686	Belongs to the peptidase S11 family
V753_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
V753_RS00105	COG1428	Deoxynucleoside kinase
V753_RS00110	COG1428	Deoxynucleoside kinase
V753_RS00115	COG1388	LysM domain
V753_RS00115	COG3858	chitin binding
V753_RS00120	COG1335	isochorismatase
V753_RS00125	COG0590	tRNA wobble adenosine to inosine editing
V753_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
V753_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
V753_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
V753_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
V753_RS00195	COG3853	Toxic anion resistance protein (TelA)
V753_RS00200	COG1982	Orn Lys Arg decarboxylase major
V753_RS00210	COG3870	Protein conserved in bacteria
V753_RS00215	COG1728	Protein conserved in bacteria
V753_RS00220	COG0470	DNA polymerase III
V753_RS00225	COG1774	PSP1 C-terminal conserved region
V753_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
V753_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
V753_RS00250	COG2002	toxin-antitoxin pair type II binding
V753_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V753_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V753_RS00260	COG0084	hydrolase, TatD family'
V753_RS00265	COG3584	3D domain protein
V753_RS00265	COG3583	domain protein
V753_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
V753_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
V753_RS00285	COG4466	Protein conserved in bacteria
V753_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
V753_RS00305	COG0251	oxidation-reduction process
V753_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
V753_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
V753_RS00345	COG2002	toxin-antitoxin pair type II binding
V753_RS00350	COG2244	polysaccharide biosynthetic process
V753_RS00355	COG3956	TIGRFAM MazG family protein
V753_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
V753_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
V753_RS00380	COG1098	S1 RNA binding domain
V753_RS00395	COG2208	phosphoserine phosphatase activity
V753_RS00400	COG2304	oxidoreductase activity
V753_RS00405	COG0515	serine threonine protein kinase
V753_RS00410	COG0037	tRNA processing
V753_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
V753_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
V753_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
V753_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
V753_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
V753_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
V753_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
V753_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
V753_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
V753_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
V753_RS00475	COG1396	sequence-specific DNA binding
V753_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
V753_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
V753_RS00565	COG4463	regulation of RNA biosynthetic process
V753_RS00570	COG3880	PFAM UvrB UvrC protein
V753_RS00580	COG0542	response to heat
V753_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
V753_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
V753_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
V753_RS00615	COG1045	serine acetyltransferase
V753_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
V753_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
V753_RS00635	COG3688	RNA-binding protein containing a PIN domain
V753_RS00640	COG1595	DNA-templated transcription, initiation
V753_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
V753_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
V753_RS00680	COG2813	Specifically methylates the guanine in position
V753_RS00695	COG1358	cellular component organization or biogenesis
V753_RS00720	COG0596	Alpha beta hydrolase
V753_RS00830	COG0201	protein transport
V753_RS00840	COG0024	Methionine aminopeptidase
V753_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
V753_RS00880	COG1122	ATPase activity
V753_RS00885	COG1122	ATPase activity
V753_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
V753_RS00910	COG2226	methyltransferase
V753_RS00915	COG2318	DinB family
V753_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
V753_RS00930	COG0489	protein tyrosine kinase activity
V753_RS00940	COG2194	sulfuric ester hydrolase activity
V753_RS00945	COG0726	polysaccharide deacetylase
V753_RS01005	COG0738	Major facilitator superfamily
V753_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
V753_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
V753_RS01030	COG0385	Bile acid
V753_RS01035	COG2819	hydrolase of the alpha beta superfamily
V753_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V753_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V753_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V753_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V753_RS01055	COG2207	Transcriptional regulator
V753_RS01060	COG3876	Protein conserved in bacteria
V753_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
V753_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
V753_RS01075	COG1263	PTS System
V753_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V753_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
V753_RS01090	COG1683	Conserved Protein
V753_RS01120	COG1595	DNA-templated transcription, initiation
V753_RS01125	COG5662	AntiSigma factor
V753_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
V753_RS01135	COG4856	YbbR-like protein
V753_RS01170	COG5002	protein histidine kinase activity
V753_RS01175	COG1136	(ABC) transporter
V753_RS01180	COG0577	efflux transmembrane transporter activity
V753_RS01200	COG1346	cytolysis
V753_RS01205	COG1380	Effector of murein hydrolase LrgA
V753_RS01210	COG1846	Transcriptional regulator
V753_RS01215	COG1113	amino acid transport
V753_RS01220	COG1011	Hydrolase
V753_RS01225	COG4585	Histidine kinase
V753_RS01230	COG2197	response regulator
V753_RS01235	COG1131	(ABC) transporter
V753_RS01275	COG0531	amino acid
V753_RS01290	COG0584	glycerophosphoryl diester phosphodiesterase
V753_RS01295	COG2271	Major facilitator Superfamily
V753_RS01305	COG2368	4-hydroxyphenylacetate
V753_RS01315	COG3409	Peptidoglycan-binding domain 1 protein
V753_RS01330	COG0371	Dehydrogenase
V753_RS01340	COG1183	phosphatidylcholine synthase activity
V753_RS01345	COG0586	Pfam SNARE associated Golgi protein
V753_RS01350	COG0688	phosphatidylethanolamine metabolic process
V753_RS01365	COG1301	dicarboxylic acid transport
V753_RS01370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
V753_RS01375	COG0833	amino acid
V753_RS01380	COG2040	homocysteine
V753_RS01385	COG1115	amino acid carrier protein
V753_RS01390	COG2066	Belongs to the glutaminase family
V753_RS01395	COG4191	Histidine kinase
V753_RS01400	COG0784	Response regulator, receiver
V753_RS01405	COG3173	Aminoglycoside phosphotransferase
V753_RS01420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
V753_RS01425	COG0778	Nitroreductase
V753_RS01430	COG0346	lactoylglutathione lyase activity
V753_RS01435	COG2259	Doxx family
V753_RS01440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V753_RS01455	COG3773	Cell wall hydrolase
V753_RS01460	COG3540	Alkaline phosphatase
V753_RS01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
V753_RS01470	COG0805	protein transport
V753_RS01480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
V753_RS01485	COG0477	Major facilitator Superfamily
V753_RS01490	COG1309	transcriptional regulator
V753_RS01495	COG0252	asparaginase activity
V753_RS01500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
V753_RS01505	COG3012	SEC-C Motif Domain Protein
V753_RS01505	COG1405	negative regulation of cell septum assembly
V753_RS01510	COG0667	Aldo Keto reductase
V753_RS01520	COG1595	DNA-templated transcription, initiation
V753_RS01525	COG1595	DNA-templated transcription, initiation
V753_RS01530	COG1876	peptidase activity
V753_RS01535	COG0457	Tetratricopeptide repeat
V753_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS01545	COG0366	Alpha amylase catalytic
V753_RS01550	COG0803	Belongs to the bacterial solute-binding protein 9 family
V753_RS01555	COG1121	(ABC) transporter
V753_RS01560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
V753_RS01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V753_RS01570	COG2310	stress, protein
V753_RS01575	COG2310	stress, protein
V753_RS01580	COG2310	stress, protein
V753_RS01585	COG0861	Integral membrane protein TerC family
V753_RS01595	COG3853	Toxic anion resistance protein (TelA)
V753_RS01600	COG0477	Major facilitator Superfamily
V753_RS01605	COG0517	IMP dehydrogenase activity
V753_RS01605	COG4175	Glycine betaine
V753_RS01610	COG4176	ABC-type proline glycine betaine transport system permease component
V753_RS01615	COG2113	Glycine betaine
V753_RS01620	COG1473	amidohydrolase
V753_RS01625	COG1288	antiporter activity
V753_RS01635	COG0366	Alpha amylase catalytic
V753_RS01645	COG2814	Major facilitator Superfamily
V753_RS01650	COG1846	Transcriptional regulator
V753_RS01655	COG1280	lysine exporter protein (LysE YggA)
V753_RS01660	COG3403	YqcI/YcgG family
V753_RS01665	COG1113	amino acid transport
V753_RS01670	COG3665	Urea carboxylase-associated protein
V753_RS01685	COG1082	Xylose isomerase domain protein TIM barrel
V753_RS01690	COG2271	Major facilitator Superfamily
V753_RS01695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
V753_RS01700	COG3458	cephalosporin-C deacetylase activity
V753_RS01705	COG3541	Predicted nucleotidyltransferase
V753_RS01710	COG0506	proline dehydrogenase activity
V753_RS01715	COG1012	belongs to the aldehyde dehydrogenase family
V753_RS01720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
V753_RS01725	COG2508	Transcriptional regulator
V753_RS01735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
V753_RS01735	COG1587	Uroporphyrinogen-III synthase
V753_RS01740	COG2146	nitrite reductase [NAD(P)H] activity
V753_RS01745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
V753_RS01750	COG0243	molybdopterin cofactor binding
V753_RS01755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
V753_RS01760	COG2223	nitrite transmembrane transporter activity
V753_RS01765	COG0523	cobalamin synthesis protein
V753_RS01770	COG1063	alcohol dehydrogenase
V753_RS01775	COG1714	RDD family
V753_RS01790	COG3209	COG3209 Rhs family protein
V753_RS01795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
V753_RS01800	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
V753_RS01805	COG1733	regulation of RNA biosynthetic process
V753_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS01840	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
V753_RS01855	COG0697	spore germination
V753_RS01860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V753_RS01870	COG2364	Membrane
V753_RS01875	COG1126	abc transporter atp-binding protein
V753_RS01880	COG0765	amino acid transport
V753_RS01885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V753_RS01890	COG0583	DNA-binding transcription factor activity
V753_RS01895	COG0163	prenyltransferase activity
V753_RS01900	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
V753_RS01915	COG3104	oligopeptide transport
V753_RS01920	COG5434	Belongs to the glycosyl hydrolase 28 family
V753_RS01930	COG0697	spore germination
V753_RS01940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
V753_RS01945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V753_RS01950	COG0456	acetyltransferase
V753_RS01955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V753_RS01960	COG0765	amino acid transport
V753_RS01965	COG1126	abc transporter atp-binding protein
V753_RS01970	COG1473	amidohydrolase
V753_RS01975	COG2079	MmgE PrpD family protein
V753_RS01980	COG1136	(ABC) transporter
V753_RS01985	COG0577	efflux transmembrane transporter activity
V753_RS01990	COG0745	RESPONSE REGULATOR receiver
V753_RS01995	COG5002	protein histidine kinase activity
V753_RS01995	COG3850	Histidine kinase
V753_RS02000	COG0457	Tetratricopeptide repeat
V753_RS02015	COG0527	aspartate kinase activity
V753_RS02020	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V753_RS02025	COG4605	iron ion homeostasis
V753_RS02030	COG4604	ABC transporter, ATP-binding protein
V753_RS02035	COG4607	ABC-type enterochelin transport system periplasmic component
V753_RS02040	COG2814	Major facilitator Superfamily
V753_RS02045	COG1309	transcriptional regulator
V753_RS02050	COG0778	Nitroreductase
V753_RS02055	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
V753_RS02060	COG0640	Transcriptional regulator
V753_RS02065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V753_RS02070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
V753_RS02075	COG1012	belongs to the aldehyde dehydrogenase family
V753_RS02080	COG4975	Glucose uptake
V753_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS02090	COG4549	nuclear export factor GLE1
V753_RS02095	COG1276	copper resistance
V753_RS02095	COG2372	response to copper ion
V753_RS02100	COG1349	DNA-binding transcription factor activity
V753_RS02110	COG2213	PTS system mannitol-specific
V753_RS02115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
V753_RS02125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
V753_RS02135	COG0561	phosphatase activity
V753_RS02145	COG1914	H( )-stimulated, divalent metal cation uptake system
V753_RS02155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
V753_RS02160	COG1984	allophanate hydrolase subunit 2
V753_RS02165	COG1414	Transcriptional regulator
V753_RS02170	COG2755	lipolytic protein G-D-S-L family
V753_RS02180	COG2329	Antibiotic biosynthesis monooxygenase
V753_RS02185	COG0768	penicillin binding
V753_RS02190	COG4989	oxidoreductase activity
V753_RS02195	COG3711	transcriptional antiterminator
V753_RS02200	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS02205	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS02210	COG1917	Cupin 2, conserved barrel domain protein
V753_RS02215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
V753_RS02220	COG3871	stress protein (general stress protein 26)
V753_RS02230	COG2814	Major facilitator Superfamily
V753_RS02235	COG1522	sequence-specific DNA binding
V753_RS02240	COG0551	DNA topoisomerase type I activity
V753_RS02240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
V753_RS02245	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
V753_RS02250	COG3706	GGDEF domain
V753_RS02255	COG5298	Protein conserved in bacteria
V753_RS02260	COG1215	transferase activity, transferring glycosyl groups
V753_RS02270	COG0531	amino acid
V753_RS02275	COG0494	nUDIX hydrolase
V753_RS02280	COG0028	Belongs to the TPP enzyme family
V753_RS02285	COG1388	LysM domain
V753_RS02285	COG5632	N-Acetylmuramoyl-L-alanine amidase
V753_RS02285	COG3409	Peptidoglycan-binding domain 1 protein
V753_RS02310	COG0457	Tetratricopeptide repeat
V753_RS02335	COG1914	H( )-stimulated, divalent metal cation uptake system
V753_RS02355	COG2076	Multidrug Resistance protein
V753_RS02360	COG2217	Heavy metal translocating P-type atpase
V753_RS02365	COG3729	General stress protein
V753_RS02370	COG0662	Cupin 2, conserved barrel domain protein
V753_RS02380	COG3546	catalase activity
V753_RS02385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
V753_RS02390	COG3290	protein histidine kinase activity
V753_RS02395	COG4565	transcriptional regulatory protein
V753_RS02400	COG1301	dicarboxylic acid transport
V753_RS02405	COG0628	permease
V753_RS02410	COG1131	(ABC) transporter
V753_RS02415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
V753_RS02425	COG1960	acyl-CoA dehydrogenase activity
V753_RS02440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
V753_RS02445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V753_RS02455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
V753_RS02460	COG0513	Belongs to the DEAD box helicase family
V753_RS02465	COG3402	PFAM membrane-flanked domain
V753_RS02470	COG3428	Bacterial PH domain
V753_RS02475	COG0705	Rhomboid family
V753_RS02485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
V753_RS02490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
V753_RS02495	COG0864	Transcriptional regulator
V753_RS02500	COG2337	Toxic component of a toxin-antitoxin (TA) module
V753_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
V753_RS02510	COG1366	Belongs to the anti-sigma-factor antagonist family
V753_RS02515	COG2172	sigma factor antagonist activity
V753_RS02520	COG2208	phosphoserine phosphatase activity
V753_RS02525	COG1366	Belongs to the anti-sigma-factor antagonist family
V753_RS02535	COG1191	sigma factor activity
V753_RS02540	COG2208	phosphoserine phosphatase activity
V753_RS02545	COG2183	response to ionizing radiation
V753_RS02605	COG2249	NAD(P)H dehydrogenase (quinone) activity
V753_RS02615	COG0477	Major facilitator Superfamily
V753_RS02630	COG2030	dehydratase
V753_RS02640	COG1959	2 iron, 2 sulfur cluster binding
V753_RS02645	COG2910	NAD(P)H-binding
V753_RS02650	COG1309	transcriptional regulator
V753_RS02655	COG0300	oxidoreductase activity
V753_RS02665	COG3239	Fatty acid desaturase
V753_RS02670	COG1278	Cold shock
V753_RS02675	COG1329	Transcriptional regulator
V753_RS02680	COG1794	racemase activity, acting on amino acids and derivatives
V753_RS02695	COG0456	acetyltransferase
V753_RS02695	COG1846	Transcriptional regulator
V753_RS02700	COG2271	Major facilitator Superfamily
V753_RS02705	COG3621	Patatin-like phospholipase
V753_RS02715	COG0662	Cupin 2, conserved barrel domain protein
V753_RS02730	COG0277	FAD linked oxidase domain protein
V753_RS02755	COG0662	Cupin 2, conserved barrel domain protein
V753_RS02760	COG2318	DinB family
V753_RS02765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
V753_RS02790	COG1064	alcohol dehydrogenase
V753_RS02795	COG0789	Transcriptional regulator
V753_RS02805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V753_RS02815	COG2814	Major facilitator Superfamily
V753_RS02820	COG1309	transcriptional regulator
V753_RS02825	COG0697	spore germination
V753_RS02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V753_RS02835	COG5577	PFAM Coat F domain
V753_RS02845	COG1063	alcohol dehydrogenase
V753_RS02850	COG5577	PFAM Coat F domain
V753_RS02860	COG4585	Histidine kinase
V753_RS02865	COG2197	response regulator
V753_RS02870	COG2409	Drug exporters of the RND superfamily
V753_RS02875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
V753_RS02880	COG0488	(ABC) transporter
V753_RS02885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
V753_RS02890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V753_RS02900	COG2814	Major facilitator Superfamily
V753_RS02905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
V753_RS02915	COG0730	response to heat
V753_RS02920	COG0456	acetyltransferase
V753_RS02925	COG0789	Transcriptional regulator
V753_RS02925	COG4978	Transcriptional regulator
V753_RS02930	COG0697	spore germination
V753_RS02935	COG1051	belongs to the nudix hydrolase family
V753_RS02940	COG0596	Alpha beta hydrolase
V753_RS02945	COG0473	3-isopropylmalate dehydrogenase activity
V753_RS02950	COG1802	Transcriptional regulator
V753_RS02955	COG1819	glycosyl
V753_RS02970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
V753_RS02980	COG1388	LysM domain
V753_RS02985	COG2814	Major facilitator Superfamily
V753_RS02990	COG2188	Transcriptional regulator
V753_RS02995	COG2186	Transcriptional regulator
V753_RS03000	COG2807	transmembrane transport
V753_RS03005	COG2076	Multidrug Resistance protein
V753_RS03010	COG2076	Multidrug Resistance protein
V753_RS03015	COG1309	transcriptional regulator
V753_RS03020	COG0531	amino acid
V753_RS03030	COG3832	glyoxalase III activity
V753_RS03035	COG0604	alcohol dehydrogenase
V753_RS03040	COG2814	Major facilitator Superfamily
V753_RS03080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
V753_RS03085	COG0802	atpase or kinase
V753_RS03090	COG1214	PFAM Peptidase M22, glycoprotease
V753_RS03095	COG0456	acetyltransferase
V753_RS03100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
V753_RS03105	COG0488	(ABC) transporter
V753_RS03120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
V753_RS03125	COG0805	protein transport
V753_RS03135	COG1266	CAAX protease self-immunity
V753_RS03150	COG1073	alpha beta
V753_RS03155	COG0457	Tetratricopeptide repeat
V753_RS03160	COG1063	alcohol dehydrogenase
V753_RS03165	COG2211	Major facilitator Superfamily
V753_RS03170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
V753_RS03180	COG1842	Phage shock protein A
V753_RS03185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
V753_RS03190	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
V753_RS03195	COG4260	virion core protein, lumpy skin disease virus
V753_RS03200	COG2755	lipolytic protein G-D-S-L family
V753_RS03200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
V753_RS03210	COG1595	DNA-templated transcription, initiation
V753_RS03215	COG1063	alcohol dehydrogenase
V753_RS03220	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
V753_RS03225	COG0823	Involved in the tonB-independent uptake of proteins
V753_RS03240	COG2132	Multicopper oxidase
V753_RS03245	COG1113	amino acid transport
V753_RS03250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
V753_RS03255	COG0714	Associated with various cellular activities
V753_RS03260	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
V753_RS03265	COG1305	Transglutaminase-like
V753_RS03290	COG2252	PERMEase
V753_RS03295	COG3064	Membrane
V753_RS03315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
V753_RS03320	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
V753_RS03325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
V753_RS03330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
V753_RS03335	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
V753_RS03350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
V753_RS03360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
V753_RS03365	COG0138	bifunctional purine biosynthesis protein purh
V753_RS03370	COG0151	Belongs to the GarS family
V753_RS03380	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
V753_RS03385	COG1470	cell adhesion involved in biofilm formation
V753_RS03390	COG4496	protein, YerC YecD
V753_RS03395	COG0069	glutamate synthase activity
V753_RS03405	COG0210	DNA helicase
V753_RS03415	COG4851	CamS sex pheromone cAM373 precursor
V753_RS03420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
V753_RS03425	COG1285	pathogenesis
V753_RS03430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
V753_RS03450	COG1309	transcriptional regulator
V753_RS03455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
V753_RS03460	COG1597	lipid kinase activity
V753_RS03465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
V753_RS03470	COG2197	response regulator
V753_RS03480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS03490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
V753_RS03500	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS03505	COG1131	(ABC) transporter
V753_RS03540	COG5444	nuclease activity
V753_RS03570	COG3546	catalase activity
V753_RS03575	COG0454	-acetyltransferase
V753_RS03585	COG2323	membrane
V753_RS03590	COG2329	Antibiotic biosynthesis monooxygenase
V753_RS03595	COG0346	lactoylglutathione lyase activity
V753_RS03600	COG1366	Belongs to the anti-sigma-factor antagonist family
V753_RS03605	COG5583	Uncharacterized small protein (DUF2292)
V753_RS03610	COG0196	riboflavin kinase activity
V753_RS03615	COG0670	Belongs to the BI1 family
V753_RS03620	COG1846	Transcriptional regulator
V753_RS03625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
V753_RS03635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
V753_RS03635	COG2124	cytochrome p450
V753_RS03650	COG1131	(ABC) transporter
V753_RS03660	COG1368	sulfuric ester hydrolase activity
V753_RS03665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
V753_RS03670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V753_RS03675	COG1442	glycosyl transferase family 8
V753_RS03680	COG1216	Glycosyl transferase, family 2
V753_RS03685	COG1442	glycosyl transferase family 8
V753_RS03690	COG2223	nitrite transmembrane transporter activity
V753_RS03695	COG0531	amino acid
V753_RS03700	COG1012	belongs to the aldehyde dehydrogenase family
V753_RS03705	COG0840	transmembrane signaling receptor activity
V753_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS03715	COG0463	Glycosyl transferase, family 2
V753_RS03715	COG0457	Tetratricopeptide repeat
V753_RS03720	COG0488	(ABC) transporter
V753_RS03725	COG0789	Transcriptional regulator
V753_RS03730	COG2814	Major facilitator Superfamily
V753_RS03735	COG0488	(ABC) transporter
V753_RS03740	COG0513	Belongs to the DEAD box helicase family
V753_RS03750	COG2130	NADP-dependent
V753_RS03765	COG3866	Pectate lyase
V753_RS03770	COG0471	metal ion transport
V753_RS03805	COG0745	RESPONSE REGULATOR receiver
V753_RS03805	COG2972	Histidine kinase
V753_RS03815	COG3279	Response regulator of the LytR AlgR family
V753_RS03825	COG3764	Sortase (surface protein transpeptidase)
V753_RS03830	COG3290	protein histidine kinase activity
V753_RS03835	COG4565	transcriptional regulatory protein
V753_RS03840	COG3181	Tripartite tricarboxylate transporter family receptor
V753_RS03845	COG2851	Citrate transporter
V753_RS03850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V753_RS03855	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
V753_RS03865	COG2258	MOSC domain
V753_RS03885	COG0024	Methionine aminopeptidase
V753_RS03890	COG1263	PTS System
V753_RS03890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V753_RS03900	COG1368	sulfuric ester hydrolase activity
V753_RS03910	COG0071	Belongs to the small heat shock protein (HSP20) family
V753_RS03925	COG1263	PTS System
V753_RS03925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V753_RS03930	COG0366	Alpha amylase catalytic
V753_RS03935	COG2188	Transcriptional regulator
V753_RS03940	COG0778	Nitroreductase
V753_RS03955	COG0737	Belongs to the 5'-nucleotidase family
V753_RS03960	COG0693	protein deglycase activity
V753_RS03965	COG1609	Transcriptional regulator
V753_RS03980	COG2814	Major facilitator Superfamily
V753_RS03990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
V753_RS03995	COG4980	gas vesicle protein
V753_RS04000	COG1295	ribonuclease BN
V753_RS04005	COG0477	Major facilitator Superfamily
V753_RS04010	COG0387	Pfam Sodium calcium exchanger
V753_RS04020	COG0668	transmembrane transport
V753_RS04025	COG0535	radical SAM domain protein
V753_RS04035	COG0726	polysaccharide deacetylase
V753_RS04040	COG2084	Dehydrogenase
V753_RS04050	COG0598	Magnesium transport protein CorA
V753_RS04055	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
V753_RS04060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
V753_RS04070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
V753_RS04075	COG4637	Psort location Cytoplasmic, score
V753_RS04080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
V753_RS04085	COG0022	dehydrogenase e1 component
V753_RS04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
V753_RS04095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
V753_RS04100	COG3284	Transcriptional regulator
V753_RS04110	COG1486	melibiose metabolic process
V753_RS04115	COG1737	Transcriptional regulator
V753_RS04120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V753_RS04120	COG1263	PTS System
V753_RS04125	COG5434	Belongs to the glycosyl hydrolase 28 family
V753_RS04130	COG1132	(ABC) transporter
V753_RS04135	COG1132	(ABC) transporter
V753_RS04140	COG2259	Doxx family
V753_RS04145	COG2514	catechol 2,3-dioxygenase activity
V753_RS04155	COG1695	Transcriptional regulator
V753_RS04160	COG2249	NAD(P)H dehydrogenase (quinone) activity
V753_RS04165	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
V753_RS04170	COG3848	Pyruvate phosphate dikinase
V753_RS04170	COG0574	Belongs to the PEP-utilizing enzyme family
V753_RS04175	COG2732	(Barnase) inhibitor
V753_RS04180	COG2318	DinB family
V753_RS04185	COG2814	Major facilitator Superfamily
V753_RS04190	COG1846	Transcriptional regulator
V753_RS04195	COG0392	lysyltransferase activity
V753_RS04195	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
V753_RS04200	COG0384	phenazine biosynthesis protein PhzF
V753_RS04205	COG0778	Nitroreductase
V753_RS04220	COG1090	epimerase
V753_RS04235	COG2814	Major facilitator Superfamily
V753_RS04245	COG3591	Belongs to the peptidase S1B family
V753_RS04260	COG3103	Sh3 type 3 domain protein
V753_RS04265	COG5658	integral membrane protein
V753_RS04270	COG0596	Alpha beta hydrolase
V753_RS04275	COG0463	Glycosyl transferase, family 2
V753_RS04280	COG4485	Bacterial membrane protein, YfhO
V753_RS04285	COG1988	membrane-bound metal-dependent
V753_RS04290	COG1194	a g-specific adenine glycosylase
V753_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS04320	COG1132	(ABC) transporter
V753_RS04325	COG4129	membrane
V753_RS04335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
V753_RS04340	COG0735	belongs to the Fur family
V753_RS04450	COG1757	Na H antiporter
V753_RS04455	COG3340	Belongs to the peptidase S51 family
V753_RS04465	COG0277	FAD linked oxidase domain protein
V753_RS04475	COG0747	negative chemotaxis
V753_RS04480	COG0601	transmembrane transport
V753_RS04485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
V753_RS04490	COG0444	Belongs to the ABC transporter superfamily
V753_RS04495	COG4608	Belongs to the ABC transporter superfamily
V753_RS04500	COG0753	catalase activity
V753_RS04510	COG1116	anion transmembrane transporter activity
V753_RS04515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
V753_RS04520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
V753_RS04540	COG1476	TRANSCRIPTIONal
V753_RS04550	COG3382	B3 4 domain protein
V753_RS04555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
V753_RS04565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
V753_RS04570	COG0789	Transcriptional regulator
V753_RS04575	COG1664	Polymer-forming cytoskeletal
V753_RS04580	COG1664	Polymer-forming cytoskeletal
V753_RS04585	COG2766	serine protein kinase
V753_RS04595	COG1846	Transcriptional regulator
V753_RS04600	COG1566	PFAM secretion protein HlyD family protein
V753_RS04605	COG2814	Major facilitator Superfamily
V753_RS04610	COG0655	NAD(P)H dehydrogenase (quinone) activity
V753_RS04625	COG1725	Transcriptional regulator
V753_RS04630	COG1131	(ABC) transporter
V753_RS04635	COG1131	(ABC) transporter
V753_RS04640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
V753_RS04645	COG1278	Cold shock
V753_RS04650	COG1464	Belongs to the NlpA lipoprotein family
V753_RS04655	COG3706	GGDEF domain
V753_RS04660	COG1823	symporter activity
V753_RS04680	COG5577	PFAM Coat F domain
V753_RS04685	COG0737	Belongs to the 5'-nucleotidase family
V753_RS04685	COG1525	nuclease
V753_RS04685	COG4085	toxin activity
V753_RS04690	COG3764	Sortase (surface protein transpeptidase)
V753_RS04695	COG0564	pseudouridine synthase activity
V753_RS04705	COG0517	IMP dehydrogenase activity
V753_RS04710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
V753_RS04715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
V753_RS04715	COG3153	acetyltransferase
V753_RS04720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
V753_RS04725	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
V753_RS04730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
V753_RS04740	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
V753_RS04745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
V753_RS04750	COG4585	Histidine kinase
V753_RS04750	COG2203	Gaf domain
V753_RS04755	COG2197	response regulator
V753_RS04760	COG0431	NADPH-dependent FMN reductase
V753_RS04775	COG0791	NLP P60 protein
V753_RS04775	COG1388	LysM domain
V753_RS04780	COG1959	2 iron, 2 sulfur cluster binding
V753_RS04790	COG2719	SpoVR family
V753_RS04795	COG1785	Belongs to the alkaline phosphatase family
V753_RS04800	COG0791	NLP P60 protein
V753_RS04800	COG1388	LysM domain
V753_RS04805	COG0583	DNA-binding transcription factor activity
V753_RS04810	COG0372	Belongs to the citrate synthase family
V753_RS04815	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS04820	COG0531	amino acid
V753_RS04825	COG0733	neurotransmitter:sodium symporter activity
V753_RS04840	COG1595	DNA-templated transcription, initiation
V753_RS04845	COG0204	Acyl-transferase
V753_RS04850	COG1253	flavin adenine dinucleotide binding
V753_RS04855	COG0789	Transcriptional regulator
V753_RS04860	COG0436	Aminotransferase
V753_RS04865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
V753_RS04870	COG1253	flavin adenine dinucleotide binding
V753_RS04875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
V753_RS04880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
V753_RS04885	COG0584	glycerophosphoryl diester phosphodiesterase
V753_RS04895	COG0668	transmembrane transport
V753_RS04900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
V753_RS04905	COG0726	polysaccharide deacetylase
V753_RS04910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
V753_RS04915	COG3226	Transcriptional regulator
V753_RS04925	COG0589	response to stress
V753_RS04930	COG1132	(ABC) transporter
V753_RS04935	COG1132	(ABC) transporter
V753_RS04940	COG0702	epimerase
V753_RS04960	COG0189	ligase activity
V753_RS04965	COG0189	ligase activity
V753_RS04980	COG4335	DNA alkylation repair
V753_RS04985	COG0561	phosphatase activity
V753_RS04990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
V753_RS05000	COG0475	glutathione-regulated potassium exporter activity
V753_RS05005	COG0490	domain, Protein
V753_RS05015	COG1024	Enoyl-CoA hydratase
V753_RS05025	COG4152	abc transporter atp-binding protein
V753_RS05030	COG1668	transmembrane transport
V753_RS05035	COG0420	3'-5' exonuclease activity
V753_RS05040	COG4717	serine-type aminopeptidase activity
V753_RS05055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
V753_RS05090	COG4980	gas vesicle protein
V753_RS05105	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
V753_RS05110	COG0537	adenosine 5'-monophosphoramidase activity
V753_RS05115	COG1131	(ABC) transporter
V753_RS05120	COG4473	ABC transporter
V753_RS05130	COG1473	amidohydrolase
V753_RS05135	COG3069	C4-dicarboxylate transmembrane transporter activity
V753_RS05140	COG2329	Antibiotic biosynthesis monooxygenase
V753_RS05145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
V753_RS05155	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
V753_RS05160	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
V753_RS05165	COG1309	transcriptional regulator
V753_RS05170	COG1511	domain protein
V753_RS05175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
V753_RS05185	COG1363	Peptidase, m42
V753_RS05190	COG1301	dicarboxylic acid transport
V753_RS05200	COG1234	tRNA 3'-trailer cleavage
V753_RS05205	COG0095	Lipoate-protein ligase
V753_RS05210	COG0702	epimerase
V753_RS05215	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS05225	COG0501	Belongs to the peptidase M48B family
V753_RS05230	COG1404	Belongs to the peptidase S8 family
V753_RS05235	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
V753_RS05240	COG0406	alpha-ribazole phosphatase activity
V753_RS05245	COG0183	Belongs to the thiolase family
V753_RS05250	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS05255	COG1268	BioY protein
V753_RS05260	COG0840	transmembrane signaling receptor activity
V753_RS05265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
V753_RS05265	COG0723	plastoquinol--plastocyanin reductase activity
V753_RS05270	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS05280	COG4903	ComK protein
V753_RS05290	COG5646	InterPro IPR014922
V753_RS05315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
V753_RS05330	COG0398	Pfam SNARE associated Golgi protein
V753_RS05335	COG0681	Belongs to the peptidase S26 family
V753_RS05340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
V753_RS05345	COG1846	Transcriptional regulator
V753_RS05350	COG3180	Ammonia monooxygenase
V753_RS05355	COG2814	Major facilitator Superfamily
V753_RS05365	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
V753_RS05370	COG2323	membrane
V753_RS05385	COG0420	3'-5' exonuclease activity
V753_RS05390	COG0419	ATPase involved in DNA repair
V753_RS05395	COG1403	HNH endonuclease
V753_RS05435	COG0179	Fumarylacetoacetate (FAA) hydrolase
V753_RS05455	COG0367	asparagine synthase
V753_RS05460	COG1562	ergosterol biosynthetic process
V753_RS05465	COG0534	Mate efflux family protein
V753_RS05470	COG1917	Cupin 2, conserved barrel domain protein
V753_RS05470	COG2207	Transcriptional regulator
V753_RS05480	COG2318	DinB family
V753_RS05485	COG1357	PFAM Pentapeptide repeats (8 copies)
V753_RS05490	COG2153	protein acetylation
V753_RS05495	COG0646	methionine synthase
V753_RS05495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
V753_RS05505	COG2996	Protein conserved in bacteria
V753_RS05510	COG1744	ABC transporter substrate-binding protein PnrA-like
V753_RS05515	COG0840	transmembrane signaling receptor activity
V753_RS05520	COG2124	cytochrome p450
V753_RS05530	COG1307	EDD domain protein, DegV family
V753_RS05535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V753_RS05555	COG0561	phosphatase activity
V753_RS05560	COG1073	alpha beta
V753_RS05565	COG2151	metal-sulfur cluster biosynthetic enzyme
V753_RS05575	COG0277	FAD linked oxidase domain protein
V753_RS05580	COG2271	Major facilitator Superfamily
V753_RS05590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
V753_RS05600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
V753_RS05605	COG0505	Belongs to the CarA family
V753_RS05610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
V753_RS05615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
V753_RS05630	COG2267	carboxylic ester hydrolase activity
V753_RS05640	COG1744	ABC transporter substrate-binding protein PnrA-like
V753_RS05655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
V753_RS05660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
V753_RS05665	COG5504	Zn-dependent protease
V753_RS05670	COG0444	Belongs to the ABC transporter superfamily
V753_RS05675	COG4608	Belongs to the ABC transporter superfamily
V753_RS05685	COG0601	transmembrane transport
V753_RS05690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
V753_RS05700	COG0180	Tryptophanyl-tRNA synthetase
V753_RS05705	COG4166	transmembrane transport
V753_RS05710	COG0601	transmembrane transport
V753_RS05715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
V753_RS05720	COG0444	Belongs to the ABC transporter superfamily
V753_RS05725	COG4608	Belongs to the ABC transporter superfamily
V753_RS05735	COG0456	acetyltransferase
V753_RS05740	COG1393	Belongs to the ArsC family
V753_RS05745	COG0861	Integral membrane protein TerC family
V753_RS05755	COG4862	establishment of competence for transformation
V753_RS05760	COG4469	Competence protein
V753_RS05765	COG1164	Oligoendopeptidase f
V753_RS05775	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
V753_RS05780	COG2346	COG2346, Truncated hemoglobins
V753_RS05785	COG0741	lytic transglycosylase activity
V753_RS05790	COG4116	CYTH
V753_RS05800	COG2357	RelA SpoT domain protein
V753_RS05805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
V753_RS05810	COG0564	pseudouridine synthase activity
V753_RS05820	COG0475	glutathione-regulated potassium exporter activity
V753_RS05820	COG0569	domain protein
V753_RS05825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
V753_RS05830	COG0352	thiamine-phosphate diphosphorylase activity
V753_RS05835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
V753_RS05840	COG2104	thiamine diphosphate biosynthetic process
V753_RS05850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
V753_RS05855	COG0351	phosphomethylpyrimidine kinase
V753_RS05860	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
V753_RS05915	COG0210	DNA helicase
V753_RS05935	COG1131	(ABC) transporter
V753_RS05945	COG2153	protein acetylation
V753_RS05955	COG2382	esterase
V753_RS05960	COG0626	cystathionine gamma-synthase activity
V753_RS05965	COG0626	cystathionine gamma-synthase activity
V753_RS05980	COG5444	nuclease activity
V753_RS05990	COG0346	lactoylglutathione lyase activity
V753_RS05995	COG2367	Beta-lactamase
V753_RS06000	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
V753_RS06005	COG0477	Major facilitator Superfamily
V753_RS06010	COG1846	Transcriptional regulator
V753_RS06020	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
V753_RS06025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
V753_RS06030	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
V753_RS06035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V753_RS06035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V753_RS06040	COG1447	Phosphotransferase system cellobiose-specific component IIA
V753_RS06070	COG1285	pathogenesis
V753_RS06085	COG2205	protein histidine kinase activity
V753_RS06095	COG3383	formate dehydrogenase (NAD+) activity
V753_RS06100	COG2427	Protein of unknown function (DUF1641)
V753_RS06105	COG2124	cytochrome p450
V753_RS06110	COG1819	glycosyl
V753_RS06120	COG1587	Uroporphyrinogen-III synthase
V753_RS06125	COG0390	transport system, permease component
V753_RS06130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
V753_RS06135	COG0697	spore germination
V753_RS06140	COG4297	protein containing double-stranded beta helix domain
V753_RS06150	COG1252	NADH dehydrogenase
V753_RS06160	COG2211	Major facilitator Superfamily
V753_RS06165	COG1609	Transcriptional regulator
V753_RS06170	COG0246	Mannitol dehydrogenase
V753_RS06175	COG2721	sulfolactate sulfo-lyase activity
V753_RS06180	COG0730	response to heat
V753_RS06185	COG2318	DinB family
V753_RS06190	COG0457	Tetratricopeptide repeat
V753_RS06200	COG1388	LysM domain
V753_RS06200	COG3409	Peptidoglycan-binding domain 1 protein
V753_RS06200	COG5632	N-Acetylmuramoyl-L-alanine amidase
V753_RS06210	COG4195	phage-related replication protein
V753_RS06215	COG2856	Zn peptidase
V753_RS06220	COG1396	sequence-specific DNA binding
V753_RS06230	COG1522	sequence-specific DNA binding
V753_RS06235	COG1484	DNA-dependent DNA replication
V753_RS06255	COG1595	DNA-templated transcription, initiation
V753_RS06260	COG3728	DNA packaging
V753_RS06260	COG5484	DNA packaging
V753_RS06265	COG1783	phage Terminase large subunit
V753_RS06270	COG5518	Phage portal protein
V753_RS06275	COG0338	D12 class N6 adenine-specific DNA methyltransferase
V753_RS06280	COG4653	Phage capsid family
V753_RS06330	COG5412	phage tail tape measure protein
V753_RS06330	COG3953	SLT domain
V753_RS06330	COG5412	phage tail tape measure protein
V753_RS06330	COG3953	SLT domain
V753_RS06330	COG5412	phage tail tape measure protein
V753_RS06330	COG3953	SLT domain
V753_RS06335	COG1652	LysM domain
V753_RS06340	COG4193	domain, Protein
V753_RS06350	COG3628	GPW Gp25 family protein
V753_RS06355	COG3299	homolog of phage Mu protein gp47
V753_RS06360	COG3778	Protein conserved in bacteria
V753_RS06400	COG3409	Peptidoglycan-binding domain 1 protein
V753_RS06400	COG5632	N-Acetylmuramoyl-L-alanine amidase
V753_RS06420	COG0306	phosphate transporter
V753_RS06425	COG1392	Phosphate transport regulator
V753_RS06430	COG0531	amino acid
V753_RS06435	COG0346	lactoylglutathione lyase activity
V753_RS06440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
V753_RS06445	COG0463	Glycosyl transferase, family 2
V753_RS06455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
V753_RS06460	COG0477	Major facilitator Superfamily
V753_RS06465	COG2362	D-Aminopeptidase
V753_RS06470	COG0601	transmembrane transport
V753_RS06475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
V753_RS06480	COG0444	Belongs to the ABC transporter superfamily
V753_RS06485	COG4166	transmembrane transport
V753_RS06490	COG1619	proteins homologs of microcin C7 resistance protein MccF
V753_RS06495	COG4948	Mandelate Racemase Muconate Lactonizing
V753_RS06500	COG0791	NLP P60 protein
V753_RS06505	COG4608	Belongs to the ABC transporter superfamily
V753_RS06510	COG2706	6-phosphogluconolactonase activity
V753_RS06515	COG1834	amidinotransferase
V753_RS06520	COG1607	acyl-coa hydrolase
V753_RS06525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
V753_RS06530	COG2076	Multidrug Resistance protein
V753_RS06535	COG2076	Multidrug Resistance protein
V753_RS06540	COG0788	formyltetrahydrofolate deformylase activity
V753_RS06545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
V753_RS06555	COG1764	response to oxidative stress
V753_RS06560	COG1846	Transcriptional regulator
V753_RS06565	COG1764	response to oxidative stress
V753_RS06580	COG0457	Tetratricopeptide repeat
V753_RS06580	COG0463	Glycosyl transferase, family 2
V753_RS06590	COG2814	Major facilitator Superfamily
V753_RS06595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
V753_RS06605	COG1404	Belongs to the peptidase S8 family
V753_RS06610	COG1366	Belongs to the anti-sigma-factor antagonist family
V753_RS06615	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
V753_RS06620	COG1122	ATPase activity
V753_RS06625	COG4721	ABC-type cobalt transport system, permease component
V753_RS06630	COG1388	LysM domain
V753_RS06630	COG3858	chitin binding
V753_RS06640	COG2239	Acts as a magnesium transporter
V753_RS06645	COG0789	Transcriptional regulator
V753_RS06660	COG1846	Transcriptional regulator
V753_RS06665	COG0726	polysaccharide deacetylase
V753_RS06670	COG1793	dna ligase
V753_RS06670	COG3285	dna ligase
V753_RS06675	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
V753_RS06680	COG0586	Pfam SNARE associated Golgi protein
V753_RS06690	COG1191	sigma factor activity
V753_RS06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
V753_RS06720	COG2323	membrane
V753_RS06730	COG3594	Acyltransferase
V753_RS06735	COG5002	protein histidine kinase activity
V753_RS06740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
V753_RS06760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
V753_RS06765	COG0436	Aminotransferase
V753_RS06795	COG3852	Histidine kinase
V753_RS06800	COG1846	Transcriptional regulator
V753_RS06805	COG1360	Flagellar Motor Protein
V753_RS06810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
V753_RS06815	COG0542	response to heat
V753_RS06820	COG3949	Membrane
V753_RS06835	COG0720	synthase
V753_RS06840	COG0602	queuosine metabolic process
V753_RS06855	COG1733	regulation of RNA biosynthetic process
V753_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS06875	COG4873	Protein conserved in bacteria
V753_RS06885	COG3773	Cell wall hydrolase
V753_RS06890	COG2244	polysaccharide biosynthetic process
V753_RS06895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V753_RS06900	COG2217	Heavy metal translocating P-type atpase
V753_RS06905	COG0006	proline dipeptidase activity
V753_RS06910	COG1609	Transcriptional regulator
V753_RS06915	COG3711	transcriptional antiterminator
V753_RS06920	COG1263	PTS System
V753_RS06920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V753_RS06920	COG2190	(PTS) system
V753_RS06925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
V753_RS06930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
V753_RS06940	COG1533	DNA photolyase activity
V753_RS06945	COG0840	transmembrane signaling receptor activity
V753_RS06950	COG2084	Dehydrogenase
V753_RS06955	COG2340	Cysteine-rich secretory protein family
V753_RS06960	COG0768	penicillin binding
V753_RS06965	COG4191	Histidine kinase
V753_RS06970	COG0436	Aminotransferase
V753_RS06980	COG0784	Response regulator, receiver
V753_RS06980	COG0835	chemotaxis
V753_RS06990	COG2814	Major facilitator Superfamily
V753_RS06995	COG1376	ErfK ybiS ycfS ynhG family protein
V753_RS07000	COG1408	metallophosphoesterase
V753_RS07005	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS07015	COG2200	EAL domain
V753_RS07020	COG4703	Protein of unknown function (DUF1797)
V753_RS07025	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
V753_RS07035	COG0517	IMP dehydrogenase activity
V753_RS07040	COG0583	DNA-binding transcription factor activity
V753_RS07045	COG0716	FMN binding
V753_RS07055	COG0716	FMN binding
V753_RS07075	COG0668	transmembrane transport
V753_RS07080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V753_RS07100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
V753_RS07105	COG0303	'Molybdopterin
V753_RS07110	COG1763	Mo-molybdopterin cofactor biosynthetic process
V753_RS07115	COG0314	molybdopterin synthase activity
V753_RS07120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
V753_RS07130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
V753_RS07135	COG1136	(ABC) transporter
V753_RS07140	COG0577	efflux transmembrane transporter activity
V753_RS07145	COG1349	DNA-binding transcription factor activity
V753_RS07150	COG1105	Belongs to the carbohydrate kinase PfkB family
V753_RS07155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
V753_RS07155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
V753_RS07155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
V753_RS07160	COG0681	Belongs to the peptidase S26 family
V753_RS07170	COG0488	(ABC) transporter
V753_RS07175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
V753_RS07180	COG2309	aminopeptidase activity
V753_RS07190	COG1077	Cell shape determining protein MreB Mrl
V753_RS07195	COG2002	toxin-antitoxin pair type II binding
V753_RS07200	COG3852	Histidine kinase
V753_RS07205	COG2105	PFAM AIG2 family protein
V753_RS07205	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
V753_RS07210	COG0569	domain protein
V753_RS07220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
V753_RS07230	COG0561	phosphatase activity
V753_RS07235	COG0242	peptide deformylase activity
V753_RS07245	COG0497	DNA recombination
V753_RS07250	COG2070	2-Nitropropane dioxygenase
V753_RS07250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
V753_RS07255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS07255	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS07255	COG3321	synthase
V753_RS07255	COG4221	oxidoreductase activity
V753_RS07260	COG4221	oxidoreductase activity
V753_RS07260	COG3321	synthase
V753_RS07260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS07260	COG0300	oxidoreductase activity
V753_RS07265	COG3321	synthase
V753_RS07265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS07265	COG4221	oxidoreductase activity
V753_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS07270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS07270	COG0300	oxidoreductase activity
V753_RS07270	COG3321	synthase
V753_RS07270	COG4221	oxidoreductase activity
V753_RS07275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS07275	COG3321	synthase
V753_RS07275	COG4221	oxidoreductase activity
V753_RS07275	COG0300	oxidoreductase activity
V753_RS07280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS07280	COG3321	synthase
V753_RS07280	COG4221	oxidoreductase activity
V753_RS07280	COG0300	oxidoreductase activity
V753_RS07285	COG4221	oxidoreductase activity
V753_RS07285	COG3321	synthase
V753_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS07285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS07290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
V753_RS07295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
V753_RS07300	COG0022	dehydrogenase e1 component
V753_RS07305	COG0508	dehydrogenase complex catalyzes the overall conversion of
V753_RS07310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
V753_RS07315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V753_RS07330	COG1982	Orn Lys Arg decarboxylase major
V753_RS07350	COG0483	inositol monophosphate 1-phosphatase activity
V753_RS07360	COG3227	Zinc metalloprotease (Elastase)
V753_RS07375	COG1595	DNA-templated transcription, initiation
V753_RS07395	COG1217	gtp-binding protein TYPA
V753_RS07405	COG4896	Protein conserved in bacteria
V753_RS07415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
V753_RS07420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
V753_RS07425	COG2066	Belongs to the glutaminase family
V753_RS07435	COG0772	Belongs to the SEDS family
V753_RS07440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
V753_RS07455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
V753_RS07455	COG2010	Cytochrome c
V753_RS07460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
V753_RS07465	COG1845	cytochrome c oxidase, subunit III
V753_RS07470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
V753_RS07475	COG3336	cytochrome c oxidase
V753_RS07485	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
V753_RS07490	COG2340	Cysteine-rich secretory protein family
V753_RS07505	COG3679	Belongs to the UPF0342 family
V753_RS07520	COG0742	ribosomal rna small subunit methyltransferase
V753_RS07530	COG3314	Sporulation integral membrane protein YlbJ
V753_RS07535	COG1752	Esterase of the alpha-beta hydrolase superfamily
V753_RS07540	COG3480	Lon protease (S16) C-terminal proteolytic domain
V753_RS07550	COG1399	metal-binding, possibly nucleic acid-binding protein
V753_RS07570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
V753_RS07590	COG4839	cell division protein FtsL
V753_RS07595	COG0768	penicillin binding
V753_RS07600	COG0768	penicillin binding
V753_RS07620	COG0772	Belongs to the SEDS family
V753_RS07635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
V753_RS07640	COG0849	cell division
V753_RS07645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
V753_RS07650	COG1404	Belongs to the peptidase S8 family
V753_RS07650	COG4412	M6 family metalloprotease domain protein
V753_RS07660	COG1191	sigma factor activity
V753_RS07665	COG1191	sigma factor activity
V753_RS07670	COG1119	ATPase activity
V753_RS07675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
V753_RS07680	COG1873	PFAM PRC-barrel domain
V753_RS07685	COG1496	oxidoreductase activity
V753_RS07690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
V753_RS07700	COG0762	integral membrane protein
V753_RS07705	COG2302	S4 RNA-binding domain
V753_RS07710	COG3599	regulation of cell shape
V753_RS07715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
V753_RS07720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
V753_RS07730	COG0564	pseudouridine synthase activity
V753_RS07740	COG2233	PERMEase
V753_RS07750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
V753_RS07755	COG0505	Belongs to the CarA family
V753_RS07760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
V753_RS07775	COG0284	orotidine-5'-phosphate decarboxylase activity
V753_RS07780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
V753_RS07790	COG0306	phosphate transporter
V753_RS07805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
V753_RS07810	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
V753_RS07815	COG1648	precorrin-2 dehydrogenase activity
V753_RS07825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
V753_RS07830	COG1561	YicC-like family, N-terminal region
V753_RS07840	COG0194	GDP metabolic process
V753_RS07850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
V753_RS07855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
V753_RS07860	COG0242	peptide deformylase activity
V753_RS07870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
V753_RS07870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
V753_RS07880	COG0631	protein serine/threonine phosphatase activity
V753_RS07885	COG0515	serine threonine protein kinase
V753_RS07885	COG2815	serine threonine protein kinase
V753_RS07895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
V753_RS07900	COG1564	THIamine pyrophosphokinase
V753_RS07915	COG1302	Protein conserved in bacteria
V753_RS07920	COG1461	Dihydroxyacetone kinase
V753_RS07925	COG1760	l-serine dehydratase
V753_RS07930	COG1760	l-serine dehydratase
V753_RS07935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
V753_RS07950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
V753_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS07970	COG1196	nuclear chromosome segregation
V753_RS07975	COG0552	protein localization to endoplasmic reticulum
V753_RS07990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
V753_RS08000	COG1837	Belongs to the UPF0109 family
V753_RS08025	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
V753_RS08040	COG2257	FlhB HrpN YscU SpaS Family
V753_RS08050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
V753_RS08055	COG0758	DNA mediated transformation
V753_RS08060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
V753_RS08070	COG4974	Belongs to the 'phage' integrase family
V753_RS08090	COG1815	bacterial-type flagellum-dependent cell motility
V753_RS08095	COG1558	bacterial-type flagellum-dependent cell motility
V753_RS08100	COG1677	Flagellar hook-basal body complex protein FliE
V753_RS08105	COG1766	The M ring may be actively involved in energy transduction
V753_RS08110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
V753_RS08115	COG1317	bacterial-type flagellum organization
V753_RS08120	COG1157	protein secretion by the type III secretion system
V753_RS08125	COG2882	bacterial-type flagellum organization
V753_RS08130	COG3334	PFAM MgtE intracellular
V753_RS08135	COG3144	bacterial-type flagellum assembly
V753_RS08140	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
V753_RS08145	COG4786	Flagellar basal body rod
V753_RS08150	COG1582	Flagellar protein (FlbD)
V753_RS08155	COG1580	Controls the rotational direction of flagella during chemotaxis
V753_RS08160	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
V753_RS08165	COG1776	CheC inhibitor of MCP methylation
V753_RS08165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
V753_RS08170	COG2201	protein-glutamate methylesterase activity
V753_RS08175	COG3190	flagellar
V753_RS08180	COG1338	Plays a role in the flagellum-specific transport system
V753_RS08185	COG1987	bacterial-type flagellum assembly
V753_RS08190	COG1684	flagellar biosynthetic protein fliR
V753_RS08195	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
V753_RS08200	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
V753_RS08205	COG1419	protein localization to endoplasmic reticulum
V753_RS08210	COG0455	bacterial-type flagellum organization
V753_RS08215	COG2201	protein-glutamate methylesterase activity
V753_RS08220	COG0643	Histidine kinase
V753_RS08220	COG2198	Histidine kinase
V753_RS08225	COG0835	chemotaxis
V753_RS08230	COG1776	CheC inhibitor of MCP methylation
V753_RS08240	COG1191	sigma factor activity
V753_RS08270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
V753_RS08275	COG4589	Belongs to the CDS family
V753_RS08285	COG0750	zinc metalloprotease
V753_RS08305	COG0195	Participates in both transcription termination and antitermination
V753_RS08310	COG2740	Nucleic-acid-binding protein implicated in transcription termination
V753_RS08315	COG1358	cellular component organization or biogenesis
V753_RS08325	COG1550	Protein conserved in bacteria
V753_RS08340	COG0196	riboflavin kinase activity
V753_RS08355	COG0726	polysaccharide deacetylase
V753_RS08360	COG0612	Peptidase, M16
V753_RS08365	COG1873	PFAM PRC-barrel domain
V753_RS08370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
V753_RS08375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
V753_RS08380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
V753_RS08385	COG0527	aspartate kinase activity
V753_RS08395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
V753_RS08400	COG0740	serine-type endopeptidase activity
V753_RS08410	COG1674	ftsk spoiiie
V753_RS08410	COG4980	gas vesicle protein
V753_RS08415	COG2188	Transcriptional regulator
V753_RS08420	COG2814	Major facilitator Superfamily
V753_RS08425	COG1846	Transcriptional regulator
V753_RS08430	COG1033	growth of symbiont in host cell
V753_RS08430	COG2409	Drug exporters of the RND superfamily
V753_RS08435	COG0612	Peptidase, M16
V753_RS08440	COG0612	Peptidase, M16
V753_RS08445	COG0300	oxidoreductase activity
V753_RS08460	COG1426	Protein conserved in bacteria
V753_RS08465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
V753_RS08480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
V753_RS08490	COG1692	metallophosphoesterase
V753_RS08495	COG2359	stage V sporulation protein S
V753_RS08515	COG4550	Control of competence regulator ComK, YlbF/YmcA
V753_RS08560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS08565	COG3425	synthase
V753_RS08570	COG1024	Enoyl-CoA hydratase
V753_RS08575	COG1024	Enoyl-CoA hydratase
V753_RS08580	COG0300	oxidoreductase activity
V753_RS08580	COG3321	synthase
V753_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS08580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS08580	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS08585	COG4221	oxidoreductase activity
V753_RS08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS08585	COG0300	oxidoreductase activity
V753_RS08585	COG3321	synthase
V753_RS08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS08590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V753_RS08590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS08590	COG3321	synthase
V753_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS08590	COG3321	synthase
V753_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS08590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS08590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V753_RS08595	COG4221	oxidoreductase activity
V753_RS08595	COG3321	synthase
V753_RS08595	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS08595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS08600	COG3321	synthase
V753_RS08600	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
V753_RS08600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
V753_RS08600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS08605	COG2124	cytochrome p450
V753_RS08610	COG3209	COG3209 Rhs family protein
V753_RS08615	COG3619	membrane
V753_RS08625	COG1404	Belongs to the peptidase S8 family
V753_RS08635	COG4195	phage-related replication protein
V753_RS08640	COG1764	response to oxidative stress
V753_RS08650	COG2076	Multidrug Resistance protein
V753_RS08690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
V753_RS08695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
V753_RS08700	COG4112	unkown
V753_RS08705	COG0860	N-Acetylmuramoyl-L-alanine amidase
V753_RS08710	COG0464	growth
V753_RS08715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
V753_RS08720	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
V753_RS08725	COG0789	Transcriptional regulator
V753_RS08730	COG0174	glutamine synthetase
V753_RS08755	COG2211	Major facilitator Superfamily
V753_RS08760	COG3507	Belongs to the glycosyl hydrolase 43 family
V753_RS08775	COG1070	Carbohydrate kinase
V753_RS08780	COG3848	Pyruvate phosphate dikinase
V753_RS08780	COG0574	Belongs to the PEP-utilizing enzyme family
V753_RS08805	COG2318	DinB family
V753_RS08810	COG1064	alcohol dehydrogenase
V753_RS08815	COG4451	ribulose bisphosphate carboxylase, small
V753_RS08815	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
V753_RS08820	COG4451	ribulose bisphosphate carboxylase, small
V753_RS08820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
V753_RS08840	COG0456	acetyltransferase
V753_RS08875	COG3397	chitin binding
V753_RS08895	COG5434	Belongs to the glycosyl hydrolase 28 family
V753_RS08900	COG0756	dUTP diphosphatase activity
V753_RS08905	COG4195	phage-related replication protein
V753_RS08940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
V753_RS08950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
V753_RS08970	COG0785	Cytochrome C biogenesis protein
V753_RS08975	COG2201	protein-glutamate methylesterase activity
V753_RS08980	COG4846	Membrane protein involved in cytochrome C biogenesis
V753_RS08990	COG0071	Belongs to the small heat shock protein (HSP20) family
V753_RS09005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
V753_RS09010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V753_RS09030	COG0824	Thioesterase
V753_RS09040	COG4841	protein insertion into membrane
V753_RS09050	COG1832	CoA-binding protein
V753_RS09055	COG0187	DNA topoisomerase II activity
V753_RS09060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
V753_RS09070	COG1115	amino acid carrier protein
V753_RS09080	COG1063	alcohol dehydrogenase
V753_RS09085	COG0800	Aldolase
V753_RS09090	COG1312	Catalyzes the dehydration of D-mannonate
V753_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS09100	COG1609	Transcriptional regulator
V753_RS09105	COG2271	Major facilitator Superfamily
V753_RS09155	COG2205	protein histidine kinase activity
V753_RS09160	COG0745	RESPONSE REGULATOR receiver
V753_RS09170	COG3507	Belongs to the glycosyl hydrolase 43 family
V753_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS09200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
V753_RS09205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
V753_RS09210	COG2610	gluconate transmembrane transporter activity
V753_RS09215	COG2124	cytochrome p450
V753_RS09235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
V753_RS09245	COG2246	polysaccharide biosynthetic process
V753_RS09250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
V753_RS09255	COG0586	Pfam SNARE associated Golgi protein
V753_RS09260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
V753_RS09265	COG1024	Enoyl-CoA hydratase
V753_RS09270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
V753_RS09275	COG0511	ligase activity, forming carbon-carbon bonds
V753_RS09280	COG0439	Biotin carboxylase
V753_RS09285	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS09290	COG1960	acyl-CoA dehydrogenase activity
V753_RS09295	COG1649	PFAM Uncharacterised BCR, COG1649
V753_RS09305	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
V753_RS09305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS09310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS09315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS09320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS09325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS09330	COG2027	D-alanyl-D-alanine carboxypeptidase
V753_RS09335	COG2017	converts alpha-aldose to the beta-anomer
V753_RS09340	COG0534	Mate efflux family protein
V753_RS09355	COG0582	viral genome integration into host DNA
V753_RS09360	COG0166	Belongs to the GPI family
V753_RS09365	COG0405	Gamma-glutamyltransferase
V753_RS09370	COG2814	Major facilitator Superfamily
V753_RS09375	COG0640	Transcriptional regulator
V753_RS09380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
V753_RS09395	COG0493	'glutamate synthase
V753_RS09400	COG0070	glutamate synthase
V753_RS09400	COG0069	glutamate synthase activity
V753_RS09400	COG0067	glutamate synthase
V753_RS09405	COG0583	DNA-binding transcription factor activity
V753_RS09410	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
V753_RS09425	COG0300	oxidoreductase activity
V753_RS09430	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
V753_RS09440	COG2814	Major facilitator Superfamily
V753_RS09445	COG1070	Carbohydrate kinase
V753_RS09450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
V753_RS09455	COG0243	molybdopterin cofactor binding
V753_RS09485	COG5444	nuclease activity
V753_RS09490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V753_RS09495	COG0662	Cupin 2, conserved barrel domain protein
V753_RS09495	COG2207	Transcriptional regulator
V753_RS09500	COG1309	transcriptional regulator
V753_RS09505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V753_RS09515	COG0640	Transcriptional regulator
V753_RS09520	COG0741	lytic transglycosylase activity
V753_RS09525	COG2322	membrane
V753_RS09540	COG1619	proteins homologs of microcin C7 resistance protein MccF
V753_RS09550	COG1388	LysM domain
V753_RS09550	COG3584	3D domain protein
V753_RS09555	COG0514	ATP-dependent DNA helicase (RecQ)
V753_RS09565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
V753_RS09570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
V753_RS09585	COG0071	Belongs to the small heat shock protein (HSP20) family
V753_RS09615	COG1012	belongs to the aldehyde dehydrogenase family
V753_RS09620	COG1657	PFAM Prenyltransferase squalene oxidase
V753_RS09625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
V753_RS09630	COG0733	neurotransmitter:sodium symporter activity
V753_RS09635	COG0385	Bile acid
V753_RS09640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V753_RS09645	COG0508	dehydrogenase complex catalyzes the overall conversion of
V753_RS09655	COG4548	von Willebrand factor, type A
V753_RS09660	COG0714	Associated with various cellular activities
V753_RS09665	COG2032	superoxide dismutase activity
V753_RS09670	COG0791	NLP P60 protein
V753_RS09670	COG1388	LysM domain
V753_RS09675	COG1819	glycosyl
V753_RS09680	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
V753_RS09685	COG0534	Mate efflux family protein
V753_RS09690	COG1366	Belongs to the anti-sigma-factor antagonist family
V753_RS09695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
V753_RS09700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
V753_RS09710	COG2962	Rard protein
V753_RS09725	COG1942	4-Oxalocrotonate Tautomerase
V753_RS09735	COG1733	regulation of RNA biosynthetic process
V753_RS09740	COG0778	Nitroreductase
V753_RS09745	COG0400	carboxylic ester hydrolase activity
V753_RS09750	COG0346	lactoylglutathione lyase activity
V753_RS09760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
V753_RS09770	COG2723	6-phospho-beta-galactosidase activity
V753_RS09775	COG2188	Transcriptional regulator
V753_RS09780	COG0793	Belongs to the peptidase S41A family
V753_RS09780	COG3409	Peptidoglycan-binding domain 1 protein
V753_RS09785	COG2226	methyltransferase
V753_RS09795	COG1876	peptidase activity
V753_RS09815	COG0671	phosphoesterase, PA-phosphatase related
V753_RS09845	COG1509	lysine 2,3-aminomutase activity
V753_RS09850	COG0456	acetyltransferase
V753_RS09855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
V753_RS09860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
V753_RS09865	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
V753_RS09870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
V753_RS09875	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
V753_RS09885	COG0456	acetyltransferase
V753_RS09890	COG0463	Glycosyl transferase, family 2
V753_RS09905	COG4641	Protein conserved in bacteria
V753_RS09915	COG1086	Polysaccharide biosynthesis protein
V753_RS09945	COG1388	LysM domain
V753_RS09950	COG0457	Tetratricopeptide repeat
V753_RS09965	COG3391	amine dehydrogenase activity
V753_RS09990	COG5444	nuclease activity
V753_RS10000	COG1525	nuclease
V753_RS10025	COG1846	Transcriptional regulator
V753_RS10030	COG4698	Protein conserved in bacteria
V753_RS10035	COG2755	lipolytic protein G-D-S-L family
V753_RS10040	COG1999	signal sequence binding
V753_RS10050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
V753_RS10055	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
V753_RS10060	COG1272	protein, Hemolysin III
V753_RS10065	COG0204	Acyl-transferase
V753_RS10070	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
V753_RS10085	COG2521	methyltransferase
V753_RS10085	COG2136	Putative SAM-dependent methyltransferase
V753_RS10100	COG1413	lyase activity
V753_RS10105	COG1418	mRNA catabolic process
V753_RS10110	COG0386	Belongs to the glutathione peroxidase family
V753_RS10120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
V753_RS10130	COG1278	Cold shock
V753_RS10150	COG0328	RNA-DNA hybrid ribonuclease activity
V753_RS10155	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
V753_RS10160	COG0328	RNA-DNA hybrid ribonuclease activity
V753_RS10170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
V753_RS10185	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
V753_RS10195	COG1755	Isoprenylcysteine carboxyl methyltransferase
V753_RS10200	COG3424	synthase
V753_RS10220	COG2323	membrane
V753_RS10225	COG1335	isochorismatase
V753_RS10235	COG2233	PERMEase
V753_RS10245	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
V753_RS10250	COG1199	ATP-dependent helicase activity
V753_RS10265	COG0116	Belongs to the methyltransferase superfamily
V753_RS10295	COG3359	exonuclease
V753_RS10300	COG1111	helicase
V753_RS10300	COG1205	dead DEAH box helicase
V753_RS10305	COG2190	(PTS) system
V753_RS10310	COG0071	Belongs to the small heat shock protein (HSP20) family
V753_RS10350	COG4499	WXG100 protein secretion system (Wss), protein YukC
V753_RS10350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
V753_RS10360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
V753_RS10365	COG3935	DnaD domain protein
V753_RS10375	COG0436	Aminotransferase
V753_RS10380	COG5353	protein conserved in bacteria
V753_RS10390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
V753_RS10390	COG1199	ATP-dependent helicase activity
V753_RS10420	COG0438	transferase activity, transferring glycosyl groups
V753_RS10425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
V753_RS10440	COG1694	Mazg nucleotide pyrophosphohydrolase
V753_RS10445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V753_RS10450	COG2140	Oxalate decarboxylase
V753_RS10460	COG4347	Protein of unknown function (DUF1405)
V753_RS10465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
V753_RS10465	COG2010	Cytochrome c
V753_RS10470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
V753_RS10475	COG0723	plastoquinol--plastocyanin reductase activity
V753_RS10490	COG0457	Tetratricopeptide repeat
V753_RS10500	COG0287	Prephenate dehydrogenase
V753_RS10535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
V753_RS10540	COG4401	Chorismate mutase type I
V753_RS10555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
V753_RS10560	COG0105	UTP biosynthetic process
V753_RS10565	COG0142	geranyltranstransferase activity
V753_RS10575	COG0142	geranyltranstransferase activity
V753_RS10590	COG0776	regulation of translation
V753_RS10595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
V753_RS10635	COG0539	negative regulation of cytoplasmic translation
V753_RS10650	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
V753_RS10655	COG2959	enzyme of heme biosynthesis
V753_RS10660	COG3409	Peptidoglycan-binding domain 1 protein
V753_RS10660	COG3773	Cell wall hydrolase
V753_RS10665	COG2339	peptidase activity
V753_RS10670	COG0492	ferredoxin-NADP+ reductase activity
V753_RS10675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
V753_RS10680	COG4862	establishment of competence for transformation
V753_RS10685	COG1408	metallophosphoesterase
V753_RS10695	COG1388	LysM domain
V753_RS10700	COG1266	CAAX protease self-immunity
V753_RS10705	COG0514	ATP-dependent DNA helicase (RecQ)
V753_RS10710	COG4955	Helix-turn-helix domain
V753_RS10715	COG1141	Ferredoxin
V753_RS10720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
V753_RS10725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
V753_RS10735	COG1595	DNA-templated transcription, initiation
V753_RS10740	COG5002	protein histidine kinase activity
V753_RS10745	COG0745	RESPONSE REGULATOR receiver
V753_RS10750	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
V753_RS10755	COG1333	cytochrome c biogenesis protein
V753_RS10760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V753_RS10765	COG1187	pseudouridine synthase activity
V753_RS10770	COG0700	Nucleoside recognition
V753_RS10775	COG2715	membrane protein required for spore maturation
V753_RS10780	COG1686	Belongs to the peptidase S11 family
V753_RS10805	COG1547	Domain of unknown function (DUF309)
V753_RS10810	COG0456	acetyltransferase
V753_RS10825	COG0307	riboflavin synthase, alpha
V753_RS10830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
V753_RS10830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
V753_RS10840	COG0681	Belongs to the peptidase S26 family
V753_RS10850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
V753_RS10855	COG4086	secreted protein
V753_RS10860	COG0019	diaminopimelate decarboxylase activity
V753_RS10865	COG0697	spore germination
V753_RS10880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
V753_RS10900	COG1191	sigma factor activity
V753_RS10910	COG1366	Belongs to the anti-sigma-factor antagonist family
V753_RS10915	COG1686	Belongs to the peptidase S11 family
V753_RS10920	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
V753_RS10925	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
V753_RS10930	COG4974	Belongs to the 'phage' integrase family
V753_RS10940	COG0735	belongs to the Fur family
V753_RS10945	COG1300	Membrane
V753_RS10960	COG0281	malic enzyme
V753_RS10965	COG1757	Na H antiporter
V753_RS10970	COG1027	Aspartate ammonia-lyase
V753_RS10975	COG0252	asparaginase activity
V753_RS10980	COG1396	sequence-specific DNA binding
V753_RS10985	COG1379	DNA repair
V753_RS10990	COG0494	nUDIX hydrolase
V753_RS11000	COG0667	Aldo Keto reductase
V753_RS11010	COG1073	alpha beta
V753_RS11020	COG4918	Iron-sulphur cluster biosynthesis
V753_RS11025	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
V753_RS11025	COG0456	acetyltransferase
V753_RS11030	COG2329	Antibiotic biosynthesis monooxygenase
V753_RS11035	COG0456	acetyltransferase
V753_RS11040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
V753_RS11055	COG0628	permease
V753_RS11065	COG0346	lactoylglutathione lyase activity
V753_RS11075	COG3048	D-serine ammonia-lyase activity
V753_RS11080	COG0300	oxidoreductase activity
V753_RS11085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V753_RS11090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
V753_RS11095	COG1024	Enoyl-CoA hydratase
V753_RS11100	COG3425	synthase
V753_RS11105	COG2124	cytochrome p450
V753_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS11110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS11110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V753_RS11110	COG3321	synthase
V753_RS11110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS11115	COG3321	synthase
V753_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS11115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS11115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V753_RS11115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS11120	COG0300	oxidoreductase activity
V753_RS11120	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS11120	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS11120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS11120	COG3321	synthase
V753_RS11125	COG0300	oxidoreductase activity
V753_RS11125	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS11125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS11125	COG3321	synthase
V753_RS11130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V753_RS11130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS11130	COG3321	synthase
V753_RS11130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS11135	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS11135	COG3321	synthase
V753_RS11135	COG0300	oxidoreductase activity
V753_RS11135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS11140	COG3321	synthase
V753_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS11140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS11140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V753_RS11140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V753_RS11145	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS11150	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS11165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
V753_RS11165	COG2070	2-Nitropropane dioxygenase
V753_RS11170	COG0250	Participates in transcription elongation, termination and antitermination
V753_RS11190	COG0596	Alpha beta hydrolase
V753_RS11205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
V753_RS11210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
V753_RS11225	COG0706	membrane insertase activity
V753_RS11230	COG2195	Cleaves the N-terminal amino acid of tripeptides
V753_RS11235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
V753_RS11240	COG0346	lactoylglutathione lyase activity
V753_RS11250	COG1376	ErfK ybiS ycfS ynhG family protein
V753_RS11255	COG4129	membrane
V753_RS11260	COG1126	abc transporter atp-binding protein
V753_RS11265	COG0765	amino acid transport
V753_RS11270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V753_RS11280	COG1597	lipid kinase activity
V753_RS11285	COG0508	dehydrogenase complex catalyzes the overall conversion of
V753_RS11290	COG0022	dehydrogenase e1 component
V753_RS11295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
V753_RS11300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
V753_RS11305	COG3426	butyrate kinase activity
V753_RS11310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
V753_RS11315	COG0280	phosphate acetyltransferase
V753_RS11320	COG3829	transcription factor binding
V753_RS11320	COG3290	protein histidine kinase activity
V753_RS11330	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
V753_RS11335	COG2079	MmgE PrpD family protein
V753_RS11340	COG0372	Belongs to the citrate synthase family
V753_RS11345	COG1960	acyl-CoA dehydrogenase activity
V753_RS11350	COG1250	3-hydroxyacyl-CoA dehydrogenase
V753_RS11355	COG0183	Belongs to the thiolase family
V753_RS11360	COG0584	glycerophosphoryl diester phosphodiesterase
V753_RS11365	COG0860	N-Acetylmuramoyl-L-alanine amidase
V753_RS11390	COG1902	pentaerythritol trinitrate reductase activity
V753_RS11405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
V753_RS11410	COG0745	RESPONSE REGULATOR receiver
V753_RS11415	COG0750	zinc metalloprotease
V753_RS11420	COG0497	DNA recombination
V753_RS11430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
V753_RS11440	COG0142	geranyltranstransferase activity
V753_RS11450	COG1570	exodeoxyribonuclease VII activity
V753_RS11465	COG1302	Protein conserved in bacteria
V753_RS11470	COG0439	Biotin carboxylase
V753_RS11475	COG0511	ligase activity, forming carbon-carbon bonds
V753_RS11515	COG3854	ATPases associated with a variety of cellular activities
V753_RS11530	COG0006	proline dipeptidase activity
V753_RS11540	COG3872	metal-dependent enzyme
V753_RS11550	COG1752	Esterase of the alpha-beta hydrolase superfamily
V753_RS11565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
V753_RS11585	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
V753_RS11600	COG1396	sequence-specific DNA binding
V753_RS11610	COG0681	Belongs to the peptidase S26 family
V753_RS11635	COG4940	Competence protein ComGF
V753_RS11645	COG4970	Tfp pilus assembly protein FimT
V753_RS11650	COG4537	Required for transformation and DNA binding
V753_RS11655	COG1459	type II secretion system
V753_RS11660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
V753_RS11665	COG0598	Magnesium transport protein CorA
V753_RS11670	COG1253	flavin adenine dinucleotide binding
V753_RS11675	COG1366	Belongs to the anti-sigma-factor antagonist family
V753_RS11685	COG1393	Belongs to the ArsC family
V753_RS11695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V753_RS11705	COG0011	TIGRFAM Protein of
V753_RS11715	COG2866	Carboxypeptidase
V753_RS11720	COG1940	carbohydrate kinase activity
V753_RS11725	COG4483	Protein conserved in bacteria
V753_RS11730	COG1757	Na H antiporter
V753_RS11740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
V753_RS11755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
V753_RS11760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
V753_RS11765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
V753_RS11770	COG0581	inorganic phosphate transmembrane transporter activity
V753_RS11775	COG0573	inorganic phosphate transmembrane transporter activity
V753_RS11780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
V753_RS11785	COG0768	penicillin binding
V753_RS11790	COG0477	Major facilitator Superfamily
V753_RS11795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
V753_RS11800	COG2839	Protein conserved in bacteria
V753_RS11805	COG5521	maltodextrose utilization protein MalA
V753_RS11810	COG1388	LysM domain
V753_RS11820	COG4709	membrane
V753_RS11825	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
V753_RS11830	COG0735	belongs to the Fur family
V753_RS11835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V753_RS11850	COG0513	Belongs to the DEAD box helicase family
V753_RS11865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
V753_RS11870	COG2384	SAM-dependent methyltransferase
V753_RS11875	COG2010	Cytochrome c
V753_RS11880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
V753_RS11885	COG0358	DNA primase activity
V753_RS11900	COG0517	IMP dehydrogenase activity
V753_RS11905	COG0751	glycine-tRNA ligase activity
V753_RS11925	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
V753_RS11930	COG0295	cytidine deaminase activity
V753_RS11935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
V753_RS11945	COG1480	7TM receptor with intracellular HD hydrolase
V753_RS11950	COG1702	phosphate starvation-inducible protein PhoH
V753_RS11955	COG0561	phosphatase activity
V753_RS11970	COG4864	UPF0365 protein
V753_RS11975	COG1030	water channel activity
V753_RS11980	COG1610	YqeY-like protein
V753_RS11990	COG1283	sodium-dependent phosphate transmembrane transporter activity
V753_RS11995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
V753_RS12000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
V753_RS12030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
V753_RS12045	COG0860	N-Acetylmuramoyl-L-alanine amidase
V753_RS12075	COG0658	competence protein
V753_RS12075	COG2333	competence protein COMEC
V753_RS12080	COG2131	deaminase
V753_RS12085	COG1555	photosystem II stabilization
V753_RS12085	COG1596	polysaccharide export
V753_RS12090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
V753_RS12095	COG2226	methyltransferase
V753_RS12100	COG0799	negative regulation of ribosome biogenesis
V753_RS12105	COG1713	HD superfamily hydrolase involved in NAD metabolism
V753_RS12115	COG1534	Rna-binding protein
V753_RS12120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
V753_RS12125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
V753_RS12130	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
V753_RS12140	COG2755	lipolytic protein G-D-S-L family
V753_RS12150	COG0398	Pfam SNARE associated Golgi protein
V753_RS12180	COG2207	Transcriptional regulator
V753_RS12180	COG3708	Transcriptional regulator
V753_RS12185	COG0563	adenylate kinase activity
V753_RS12195	COG0456	acetyltransferase
V753_RS12200	COG2318	DinB family
V753_RS12210	COG0561	phosphatase activity
V753_RS12215	COG0561	phosphatase activity
V753_RS12225	COG1482	cell wall glycoprotein biosynthetic process
V753_RS12230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
V753_RS12230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
V753_RS12230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
V753_RS12235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
V753_RS12235	COG3711	transcriptional antiterminator
V753_RS12245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
V753_RS12250	COG0583	DNA-binding transcription factor activity
V753_RS12255	COG2814	Major facilitator Superfamily
V753_RS12260	COG2124	cytochrome p450
V753_RS12260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
V753_RS12265	COG1309	transcriptional regulator
V753_RS12270	COG2226	methyltransferase
V753_RS12285	COG2116	formate transmembrane transporter activity
V753_RS12290	COG5609	conserved protein (DUF2294)
V753_RS12295	COG3383	formate dehydrogenase (NAD+) activity
V753_RS12300	COG2427	Protein of unknown function (DUF1641)
V753_RS12310	COG0626	cystathionine gamma-synthase activity
V753_RS12315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
V753_RS12340	COG0768	penicillin binding
V753_RS12355	COG0826	peptidase U32
V753_RS12360	COG0826	peptidase U32
V753_RS12365	COG4122	O-methyltransferase activity
V753_RS12370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
V753_RS12395	COG0628	permease
V753_RS12400	COG1126	abc transporter atp-binding protein
V753_RS12405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V753_RS12410	COG0765	amino acid transport
V753_RS12415	COG0765	amino acid transport
V753_RS12430	COG3881	PFAM PRC-barrel domain
V753_RS12435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
V753_RS12440	COG0457	Tetratricopeptide repeat
V753_RS12450	COG1104	cysteine desulfurase activity
V753_RS12455	COG1959	2 iron, 2 sulfur cluster binding
V753_RS12460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
V753_RS12465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
V753_RS12490	COG3103	Sh3 type 3 domain protein
V753_RS12490	COG0860	N-Acetylmuramoyl-L-alanine amidase
V753_RS12490	COG4991	sh3 domain protein
V753_RS12500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
V753_RS12510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
V753_RS12510	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
V753_RS12515	COG5416	Lipopolysaccharide assembly protein A domain
V753_RS12520	COG0490	domain, Protein
V753_RS12525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
V753_RS12525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
V753_RS12535	COG2244	polysaccharide biosynthetic process
V753_RS12540	COG2323	membrane
V753_RS12550	COG1862	Preprotein translocase
V753_RS12590	COG1388	LysM domain
V753_RS12600	COG0157	Belongs to the NadC ModD family
V753_RS12605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
V753_RS12610	COG1104	cysteine desulfurase activity
V753_RS12615	COG1827	regulation of RNA biosynthetic process
V753_RS12620	COG0077	Prephenate dehydratase
V753_RS12635	COG3290	protein histidine kinase activity
V753_RS12640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
V753_RS12645	COG2868	ribosomal protein
V753_RS12655	COG1994	Peptidase M50
V753_RS12660	COG0739	heme binding
V753_RS12665	COG2894	cell division
V753_RS12675	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
V753_RS12685	COG1077	Cell shape determining protein MreB Mrl
V753_RS12705	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
V753_RS12710	COG0285	dihydrofolate synthase activity
V753_RS12715	COG0525	valine-tRNA ligase activity
V753_RS12725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
V753_RS12730	COG1388	LysM domain
V753_RS12740	COG0113	porphobilinogen synthase activity
V753_RS12745	COG1587	Uroporphyrinogen-III synthase
V753_RS12755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
V753_RS12775	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
V753_RS12780	COG1067	ATP-dependent peptidase activity
V753_RS12780	COG0470	DNA polymerase III
V753_RS12795	COG0457	Tetratricopeptide repeat
V753_RS12795	COG1477	protein flavinylation
V753_RS12810	COG0473	3-isopropylmalate dehydrogenase activity
V753_RS12825	COG0440	acetolactate synthase activity
V753_RS12830	COG0028	Belongs to the TPP enzyme family
V753_RS12875	COG0622	Phosphoesterase
V753_RS12880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
V753_RS12890	COG5401	PFAM Sporulation and spore germination
V753_RS12900	COG1846	Transcriptional regulator
V753_RS12905	COG2197	response regulator
V753_RS12910	COG0824	Thioesterase
V753_RS12915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
V753_RS12920	COG1053	succinate dehydrogenase
V753_RS12925	COG2009	succinate dehydrogenase
V753_RS12930	COG1719	4-vinyl reductase, 4VR
V753_RS12935	COG0527	aspartate kinase activity
V753_RS12945	COG3118	belongs to the thioredoxin family
V753_RS12950	COG3534	alpha-L-arabinofuranosidase
V753_RS12955	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
V753_RS12960	COG2086	electron transfer activity
V753_RS12965	COG1024	Enoyl-CoA hydratase
V753_RS12970	COG1309	transcriptional regulator
V753_RS12975	COG0318	PFAM AMP-dependent synthetase and ligase
V753_RS12985	COG3766	membrane
V753_RS12995	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
V753_RS12995	COG1796	DNA polymerase
V753_RS13000	COG1286	toxin biosynthetic process
V753_RS13015	COG0072	phenylalanine-tRNA ligase activity
V753_RS13015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V753_RS13020	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
V753_RS13025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
V753_RS13035	COG3835	regulator
V753_RS13040	COG0277	FAD linked oxidase domain protein
V753_RS13045	COG0247	lactate metabolic process
V753_RS13050	COG1966	Carbon starvation protein
V753_RS13055	COG3534	alpha-L-arabinofuranosidase
V753_RS13060	COG0395	ABC-type sugar transport system, permease component
V753_RS13065	COG1175	transmembrane transport
V753_RS13070	COG1653	transport
V753_RS13080	COG0647	UMP catabolic process
V753_RS13085	COG0235	Class ii aldolase
V753_RS13090	COG1069	ribulokinase activity
V753_RS13095	COG2160	L-arabinose isomerase activity
V753_RS13100	COG3507	Belongs to the glycosyl hydrolase 43 family
V753_RS13105	COG1363	Peptidase, m42
V753_RS13115	COG3326	Membrane
V753_RS13130	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
V753_RS13135	COG1346	cytolysis
V753_RS13140	COG1380	Effector of murein hydrolase LrgA
V753_RS13145	COG3279	Response regulator of the LytR AlgR family
V753_RS13150	COG3275	phosphorelay sensor kinase activity
V753_RS13155	COG1011	Hydrolase
V753_RS13170	COG0398	Pfam SNARE associated Golgi protein
V753_RS13175	COG1484	DNA-dependent DNA replication
V753_RS13180	COG3611	Membrane attachment protein
V753_RS13195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
V753_RS13200	COG1733	regulation of RNA biosynthetic process
V753_RS13205	COG2814	Major facilitator Superfamily
V753_RS13210	COG0656	L-ascorbic acid biosynthetic process
V753_RS13215	COG0237	dephospho-CoA kinase activity
V753_RS13220	COG1971	Probably functions as a manganese efflux pump
V753_RS13225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
V753_RS13230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
V753_RS13230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
V753_RS13235	COG5002	protein histidine kinase activity
V753_RS13240	COG0745	RESPONSE REGULATOR receiver
V753_RS13250	COG0538	isocitrate dehydrogenase activity
V753_RS13255	COG0372	Belongs to the citrate synthase family
V753_RS13270	COG0628	permease
V753_RS13275	COG3030	protein affecting phage T7 exclusion by the F plasmid
V753_RS13280	COG0469	pyruvate kinase activity
V753_RS13300	COG0281	malic enzyme
V753_RS13305	COG0587	DNA-directed DNA polymerase activity
V753_RS13325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
V753_RS13335	COG4109	DRTGG domain
V753_RS13345	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS13360	COG0521	Mo-molybdopterin cofactor biosynthetic process
V753_RS13370	COG0827	DNA restriction-modification system
V753_RS13375	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
V753_RS13380	COG3874	Sporulation protein YtfJ
V753_RS13390	COG1714	RDD family
V753_RS13395	COG0616	signal peptide processing
V753_RS13400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
V753_RS13405	COG1574	metal-dependent hydrolase with the TIM-barrel fold
V753_RS13410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
V753_RS13425	COG1104	cysteine desulfurase activity
V753_RS13430	COG1114	Component of the transport system for branched-chain amino acids
V753_RS13440	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
V753_RS13445	COG1309	transcriptional regulator
V753_RS13450	COG1956	GAF domain-containing protein
V753_RS13455	COG2199	diguanylate cyclase activity
V753_RS13455	COG2203	Gaf domain
V753_RS13465	COG1012	belongs to the aldehyde dehydrogenase family
V753_RS13500	COG1017	nitric oxide dioxygenase activity
V753_RS13500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
V753_RS13510	COG0693	protein deglycase activity
V753_RS13525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
V753_RS13530	COG1378	Sugar-specific transcriptional regulator TrmB
V753_RS13550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
V753_RS13555	COG0454	-acetyltransferase
V753_RS13560	COG0517	IMP dehydrogenase activity
V753_RS13565	COG0123	including yeast histone deacetylase and acetoin utilization protein
V753_RS13570	COG1360	Flagellar Motor Protein
V753_RS13575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
V753_RS13580	COG1609	Transcriptional regulator
V753_RS13585	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
V753_RS13585	COG1605	Chorismate mutase
V753_RS13590	COG3118	belongs to the thioredoxin family
V753_RS13595	COG4980	gas vesicle protein
V753_RS13600	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
V753_RS13610	COG1674	ftsk spoiiie
V753_RS13615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V753_RS13625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V753_RS13635	COG1363	Peptidase, m42
V753_RS13640	COG5584	Small secreted protein
V753_RS13645	COG0281	malic enzyme
V753_RS13650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V753_RS13665	COG0510	thiamine kinase activity
V753_RS13670	COG1597	lipid kinase activity
V753_RS13680	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
V753_RS13685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
V753_RS13690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
V753_RS13695	COG2252	PERMEase
V753_RS13700	COG4473	ABC transporter
V753_RS13705	COG1131	(ABC) transporter
V753_RS13710	COG1349	DNA-binding transcription factor activity
V753_RS13715	COG1187	pseudouridine synthase activity
V753_RS13720	COG2244	polysaccharide biosynthetic process
V753_RS13725	COG2081	HI0933 family
V753_RS13730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
V753_RS13740	COG1609	Transcriptional regulator
V753_RS13745	COG1653	transport
V753_RS13750	COG1175	transmembrane transport
V753_RS13755	COG0395	ABC-type sugar transport system, permease component
V753_RS13760	COG1486	melibiose metabolic process
V753_RS13770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
V753_RS13785	COG1366	Belongs to the anti-sigma-factor antagonist family
V753_RS13785	COG2202	Pas domain
V753_RS13790	COG2814	Major facilitator Superfamily
V753_RS13795	COG5522	Integral membrane protein (intg_mem_TP0381)
V753_RS13800	COG0577	efflux transmembrane transporter activity
V753_RS13805	COG1136	(ABC) transporter
V753_RS13810	COG2205	protein histidine kinase activity
V753_RS13815	COG0745	RESPONSE REGULATOR receiver
V753_RS13820	COG0577	efflux transmembrane transporter activity
V753_RS13825	COG1136	(ABC) transporter
V753_RS13845	COG1131	(ABC) transporter
V753_RS13850	COG1725	Transcriptional regulator
V753_RS13865	COG1242	4 iron, 4 sulfur cluster binding
V753_RS13870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
V753_RS13890	COG2267	carboxylic ester hydrolase activity
V753_RS13895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
V753_RS13900	COG1113	amino acid transport
V753_RS13905	COG0367	asparagine synthase
V753_RS13925	COG1506	peptidase
V753_RS13930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
V753_RS13935	COG1116	anion transmembrane transporter activity
V753_RS13940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
V753_RS13945	COG0494	nUDIX hydrolase
V753_RS13950	COG4824	toxin secretion phage lysis holin
V753_RS13955	COG0783	Belongs to the Dps family
V753_RS13980	COG0288	reversible hydration of carbon dioxide
V753_RS13990	COG1271	oxidase subunit
V753_RS13995	COG1294	oxidase, subunit
V753_RS14005	COG4948	Mandelate Racemase Muconate Lactonizing
V753_RS14015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
V753_RS14020	COG0596	Alpha beta hydrolase
V753_RS14030	COG1169	isochorismate synthase
V753_RS14035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
V753_RS14040	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
V753_RS14165	COG3859	Proton-coupled thiamine transporter YuaJ
V753_RS14170	COG2268	Band 7 protein
V753_RS14175	COG1585	Membrane protein implicated in regulation of membrane protease activity
V753_RS14180	COG2318	DinB family
V753_RS14190	COG1454	alcohol dehydrogenase
V753_RS14195	COG1012	belongs to the aldehyde dehydrogenase family
V753_RS14200	COG1510	regulation of RNA biosynthetic process
V753_RS14210	COG0569	domain protein
V753_RS14215	COG1705	Flagellar rod assembly protein muramidase FlgJ
V753_RS14220	COG1017	nitric oxide dioxygenase activity
V753_RS14220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
V753_RS14245	COG0628	permease
V753_RS14250	COG0673	inositol 2-dehydrogenase activity
V753_RS14255	COG0693	protein deglycase activity
V753_RS14260	COG0840	transmembrane signaling receptor activity
V753_RS14265	COG0840	transmembrane signaling receptor activity
V753_RS14270	COG0840	transmembrane signaling receptor activity
V753_RS14275	COG0840	transmembrane signaling receptor activity
V753_RS14290	COG2070	2-Nitropropane dioxygenase
V753_RS14295	COG0432	Pfam Uncharacterised protein family UPF0047
V753_RS14300	COG0366	Alpha amylase catalytic
V753_RS14305	COG1253	flavin adenine dinucleotide binding
V753_RS14310	COG2738	Putative neutral zinc metallopeptidase
V753_RS14325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
V753_RS14350	COG1335	isochorismatase
V753_RS14355	COG1979	alcohol dehydrogenase
V753_RS14360	COG1979	alcohol dehydrogenase
V753_RS14365	COG2155	Conserved Protein
V753_RS14370	COG1098	S1 RNA binding domain
V753_RS14375	COG0436	Aminotransferase
V753_RS14380	COG1522	sequence-specific DNA binding
V753_RS14385	COG2267	carboxylic ester hydrolase activity
V753_RS14395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
V753_RS14400	COG2205	protein histidine kinase activity
V753_RS14410	COG5018	Exonuclease
V753_RS14415	COG2814	Major facilitator Superfamily
V753_RS14420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
V753_RS14425	COG3011	Protein conserved in bacteria
V753_RS14435	COG3290	protein histidine kinase activity
V753_RS14440	COG4565	transcriptional regulatory protein
V753_RS14445	COG1744	ABC transporter substrate-binding protein PnrA-like
V753_RS14450	COG3845	ABC transporter
V753_RS14455	COG4603	Belongs to the binding-protein-dependent transport system permease family
V753_RS14460	COG1079	Belongs to the binding-protein-dependent transport system permease family
V753_RS14470	COG2111	Na H antiporter
V753_RS14470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
V753_RS14475	COG2111	Na H antiporter
V753_RS14480	COG1006	Multisubunit Na H antiporter MnhC subunit
V753_RS14485	COG0651	ATP synthesis coupled electron transport
V753_RS14490	COG1863	multisubunit Na H antiporter MnhE subunit
V753_RS14495	COG2212	antiporter activity
V753_RS14500	COG1320	monovalent cation:proton antiporter activity
V753_RS14505	COG2050	protein possibly involved in aromatic compounds catabolism
V753_RS14510	COG2197	response regulator
V753_RS14515	COG4585	Histidine kinase
V753_RS14525	COG0142	geranyltranstransferase activity
V753_RS14540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
V753_RS14545	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
V753_RS14550	COG1335	isochorismatase
V753_RS14555	COG5506	Protein of unknown function (DUF1694)
V753_RS14570	COG0628	permease
V753_RS14580	COG1418	mRNA catabolic process
V753_RS14585	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS14595	COG1511	domain protein
V753_RS14600	COG0433	COG0433 Predicted ATPase
V753_RS14600	COG1674	ftsk spoiiie
V753_RS14605	COG4499	WXG100 protein secretion system (Wss), protein YukC
V753_RS14610	COG5417	Belongs to the EsaB family
V753_RS14615	COG4842	Belongs to the WXG100 family
V753_RS14620	COG2508	Transcriptional regulator
V753_RS14620	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
V753_RS14625	COG0686	Belongs to the AlaDH PNT family
V753_RS14630	COG5634	Uncharacterized conserved protein (DUF2278)
V753_RS14635	COG3251	PFAM MbtH domain protein
V753_RS14640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V753_RS14645	COG1535	isochorismatase
V753_RS14645	COG3433	isochorismatase activity
V753_RS14650	COG1021	2,3-dihydroxybenzoate-AMP ligase
V753_RS14655	COG1169	isochorismate synthase
V753_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS14665	COG2819	hydrolase of the alpha beta superfamily
V753_RS14670	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
V753_RS14675	COG1268	BioY protein
V753_RS14680	COG2056	Na+-H+ antiporter family
V753_RS14690	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
V753_RS14695	COG3584	3D domain protein
V753_RS14710	COG1252	NADH dehydrogenase
V753_RS14740	COG1131	(ABC) transporter
V753_RS14765	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
V753_RS14770	COG0316	Belongs to the HesB IscA family
V753_RS14780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
V753_RS14790	COG1252	NADH dehydrogenase
V753_RS14795	COG4837	Protein of unknown function (DUF1462)
V753_RS14800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
V753_RS14805	COG0823	Involved in the tonB-independent uptake of proteins
V753_RS14805	COG1506	peptidase
V753_RS14805	COG4946	Tricorn protease homolog
V753_RS14815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
V753_RS14820	COG0460	homoserine dehydrogenase
V753_RS14825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
V753_RS14830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
V753_RS14835	COG0647	UMP catabolic process
V753_RS14840	COG2445	Protein of unknown function DUF86
V753_RS14845	COG4470	Protein conserved in bacteria
V753_RS14855	COG0739	heme binding
V753_RS14865	COG0737	Belongs to the 5'-nucleotidase family
V753_RS14870	COG0730	response to heat
V753_RS14875	COG1801	Protein of unknown function DUF72
V753_RS14890	COG2508	Transcriptional regulator
V753_RS14910	COG2814	Major facilitator Superfamily
V753_RS14915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
V753_RS14920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
V753_RS14925	COG2356	endonuclease I
V753_RS14930	COG3842	ATPase activity
V753_RS14935	COG2188	Transcriptional regulator
V753_RS14940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
V753_RS14945	COG0395	ABC-type sugar transport system, permease component
V753_RS14950	COG1175	transmembrane transport
V753_RS14955	COG1653	transport
V753_RS14960	COG2222	sugar isomerase
V753_RS14970	COG0322	excinuclease ABC activity
V753_RS14975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
V753_RS14980	COG2226	methyltransferase
V753_RS14990	COG3409	Peptidoglycan-binding domain 1 protein
V753_RS14995	COG0719	Fe-S assembly protein
V753_RS15000	COG0822	iron-sulfur transferase activity
V753_RS15005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
V753_RS15010	COG0719	Fe-S assembly protein
V753_RS15015	COG0396	ATPase activity
V753_RS15025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
V753_RS15030	COG1464	Belongs to the NlpA lipoprotein family
V753_RS15035	COG2011	ABC-type metal ion transport system permease component
V753_RS15040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
V753_RS15050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V753_RS15055	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
V753_RS15070	COG1393	Belongs to the ArsC family
V753_RS15075	COG1960	acyl-CoA dehydrogenase activity
V753_RS15080	COG0183	Belongs to the thiolase family
V753_RS15085	COG1250	3-hydroxyacyl-CoA dehydrogenase
V753_RS15085	COG1024	Enoyl-CoA hydratase
V753_RS15105	COG5577	PFAM Coat F domain
V753_RS15110	COG1846	Transcriptional regulator
V753_RS15115	COG0477	Major facilitator Superfamily
V753_RS15120	COG0583	DNA-binding transcription factor activity
V753_RS15140	COG1120	ATPase activity
V753_RS15155	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS15160	COG0783	Belongs to the Dps family
V753_RS15165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
V753_RS15170	COG0745	RESPONSE REGULATOR receiver
V753_RS15175	COG2205	protein histidine kinase activity
V753_RS15175	COG2770	Histidine kinase
V753_RS15185	COG1309	transcriptional regulator
V753_RS15190	COG0114	fumarate hydratase activity
V753_RS15200	COG0697	spore germination
V753_RS15205	COG0814	amino acid
V753_RS15215	COG2197	response regulator
V753_RS15220	COG4585	Histidine kinase
V753_RS15225	COG4758	membrane
V753_RS15230	COG3595	metallopeptidase activity
V753_RS15235	COG1842	Phage shock protein A
V753_RS15240	COG4758	membrane
V753_RS15245	COG2814	Major facilitator Superfamily
V753_RS15250	COG2096	Adenosyltransferase
V753_RS15255	COG1120	ATPase activity
V753_RS15260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V753_RS15265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V753_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS15275	COG3386	PFAM SMP-30 Gluconolaconase
V753_RS15280	COG2205	protein histidine kinase activity
V753_RS15285	COG0745	RESPONSE REGULATOR receiver
V753_RS15295	COG1191	sigma factor activity
V753_RS15305	COG2140	Oxalate decarboxylase
V753_RS15315	COG1120	ATPase activity
V753_RS15320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V753_RS15325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V753_RS15330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V753_RS15335	COG0531	amino acid
V753_RS15345	COG1988	membrane-bound metal-dependent
V753_RS15350	COG1368	sulfuric ester hydrolase activity
V753_RS15355	COG1910	domain protein
V753_RS15360	COG0725	ABC transporter, periplasmic molybdate-binding protein
V753_RS15365	COG4149	molybdate abc transporter
V753_RS15370	COG2197	response regulator
V753_RS15375	COG3850	Histidine kinase
V753_RS15380	COG1131	(ABC) transporter
V753_RS15390	COG0842	Transport permease protein
V753_RS15395	COG0656	L-ascorbic acid biosynthetic process
V753_RS15415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
V753_RS15420	COG3973	AAA domain
V753_RS15425	COG2860	membrane
V753_RS15435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
V753_RS15440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
V753_RS15445	COG2217	Heavy metal translocating P-type atpase
V753_RS15450	COG2217	Heavy metal translocating P-type atpase
V753_RS15455	COG2608	mercury ion transmembrane transporter activity
V753_RS15460	COG1937	Protein conserved in bacteria
V753_RS15465	COG0673	inositol 2-dehydrogenase activity
V753_RS15475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V753_RS15480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
V753_RS15485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V753_RS15490	COG1126	abc transporter atp-binding protein
V753_RS15495	COG0765	amino acid transport
V753_RS15500	COG0765	amino acid transport
V753_RS15505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V753_RS15510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V753_RS15515	COG0454	-acetyltransferase
V753_RS15520	COG0583	DNA-binding transcription factor activity
V753_RS15525	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS15530	COG2732	(Barnase) inhibitor
V753_RS15545	COG0557	exoribonuclease II activity
V753_RS15550	COG1647	Serine aminopeptidase, S33
V753_RS15555	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
V753_RS15560	COG1476	TRANSCRIPTIONal
V753_RS15565	COG1396	sequence-specific DNA binding
V753_RS15570	COG1396	sequence-specific DNA binding
V753_RS15575	COG1733	regulation of RNA biosynthetic process
V753_RS15600	COG1131	(ABC) transporter
V753_RS15605	COG1174	glycine betaine transport
V753_RS15610	COG1732	Glycine betaine
V753_RS15615	COG1174	glycine betaine transport
V753_RS15620	COG1125	glycine betaine transport
V753_RS15620	COG0517	IMP dehydrogenase activity
V753_RS15625	COG1510	regulation of RNA biosynthetic process
V753_RS15630	COG1174	glycine betaine transport
V753_RS15635	COG1732	Glycine betaine
V753_RS15640	COG1174	glycine betaine transport
V753_RS15645	COG1125	glycine betaine transport
V753_RS15645	COG0517	IMP dehydrogenase activity
V753_RS15650	COG1510	regulation of RNA biosynthetic process
V753_RS15655	COG2095	MarC family integral membrane protein
V753_RS15660	COG3064	Membrane
V753_RS15665	COG4640	response to antibiotic
V753_RS15670	COG0456	acetyltransferase
V753_RS15685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
V753_RS15705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V753_RS15710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
V753_RS15720	COG2234	aminopeptidase activity
V753_RS15740	COG0126	phosphoglycerate kinase activity
V753_RS15745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
V753_RS15750	COG2390	Transcriptional regulator
V753_RS15755	COG2814	Major facilitator Superfamily
V753_RS15760	COG1609	Transcriptional regulator
V753_RS15765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V753_RS15775	COG0583	DNA-binding transcription factor activity
V753_RS15780	COG0697	spore germination
V753_RS15785	COG1113	amino acid transport
V753_RS15795	COG1737	Transcriptional regulator
V753_RS15800	COG1070	Carbohydrate kinase
V753_RS15825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V753_RS15830	COG2186	Transcriptional regulator
V753_RS15835	COG1620	l-lactate permease
V753_RS15840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
V753_RS15850	COG5039	Polysaccharide pyruvyl transferase
V753_RS15855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
V753_RS15860	COG0110	maltose O-acetyltransferase activity
V753_RS15865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
V753_RS15870	COG2244	polysaccharide biosynthetic process
V753_RS15875	COG1216	Glycosyl transferase, family 2
V753_RS15880	COG5039	Polysaccharide pyruvyl transferase
V753_RS15885	COG1216	Glycosyl transferase, family 2
V753_RS15895	COG0438	transferase activity, transferring glycosyl groups
V753_RS15900	COG1215	transferase activity, transferring glycosyl groups
V753_RS15905	COG0438	transferase activity, transferring glycosyl groups
V753_RS15910	COG1086	Polysaccharide biosynthesis protein
V753_RS15915	COG0489	protein tyrosine kinase activity
V753_RS15920	COG3944	biosynthesis protein
V753_RS15925	COG1396	sequence-specific DNA binding
V753_RS15930	COG2272	Belongs to the type-B carboxylesterase lipase family
V753_RS15940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
V753_RS15945	COG2364	Membrane
V753_RS15950	COG0456	acetyltransferase
V753_RS15955	COG3479	Phenolic acid decarboxylase
V753_RS16005	COG2223	nitrite transmembrane transporter activity
V753_RS16010	COG1609	Transcriptional regulator
V753_RS16020	COG0583	DNA-binding transcription factor activity
V753_RS16025	COG2828	Protein conserved in bacteria
V753_RS16030	COG0477	Major facilitator Superfamily
V753_RS16030	COG2814	Major facilitator Superfamily
V753_RS16035	COG1611	Belongs to the LOG family
V753_RS16040	COG1694	Mazg nucleotide pyrophosphohydrolase
V753_RS16045	COG0659	secondary active sulfate transmembrane transporter activity
V753_RS16050	COG0288	reversible hydration of carbon dioxide
V753_RS16055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
V753_RS16060	COG4290	ribonuclease
V753_RS16065	COG2162	N-hydroxyarylamine O-acetyltransferase activity
V753_RS16070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
V753_RS16080	COG0391	Required for morphogenesis under gluconeogenic growth conditions
V753_RS16090	COG1051	belongs to the nudix hydrolase family
V753_RS16095	COG0492	ferredoxin-NADP+ reductase activity
V753_RS16100	COG0791	NLP P60 protein
V753_RS16100	COG3883	PFAM NLP P60 protein
V753_RS16105	COG0457	Tetratricopeptide repeat
V753_RS16110	COG5002	protein histidine kinase activity
V753_RS16115	COG0745	RESPONSE REGULATOR receiver
V753_RS16120	COG1132	(ABC) transporter
V753_RS16125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
V753_RS16125	COG0140	phosphoribosyl-ATP diphosphatase activity
V753_RS16150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
V753_RS16165	COG4990	cell redox homeostasis
V753_RS16170	COG0110	maltose O-acetyltransferase activity
V753_RS16190	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
V753_RS16200	COG2188	Transcriptional regulator
V753_RS16205	COG1309	transcriptional regulator
V753_RS16210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
V753_RS16215	COG1950	PFAM Membrane protein of
V753_RS16220	COG1983	PspC domain protein
V753_RS16225	COG3595	metallopeptidase activity
V753_RS16240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
V753_RS16250	COG4897	Protein conserved in bacteria
V753_RS16255	COG3848	Pyruvate phosphate dikinase
V753_RS16255	COG0574	Belongs to the PEP-utilizing enzyme family
V753_RS16260	COG1309	transcriptional regulator
V753_RS16265	COG2814	Major facilitator Superfamily
V753_RS16295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
V753_RS16305	COG0793	Belongs to the peptidase S41A family
V753_RS16305	COG3409	Peptidoglycan-binding domain 1 protein
V753_RS16310	COG3420	alginic acid biosynthetic process
V753_RS16315	COG2177	Part of the ABC transporter FtsEX involved in
V753_RS16320	COG2884	Cell division ATP-binding protein ftsE
V753_RS16325	COG2010	Cytochrome c
V753_RS16330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V753_RS16345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
V753_RS16360	COG1516	flagellar protein fliS
V753_RS16365	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
V753_RS16370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
V753_RS16390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
V753_RS16395	COG4786	Flagellar basal body rod
V753_RS16395	COG1256	bacterial-type flagellum assembly
V753_RS16400	COG3418	PFAM FlgN family protein
V753_RS16405	COG2747	anti-sigma28 factor FlgM
V753_RS16415	COG1040	competence protein
V753_RS16425	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
V753_RS16430	COG1307	EDD domain protein, DegV family
V753_RS16435	COG2197	response regulator
V753_RS16440	COG4585	Histidine kinase
V753_RS16445	COG1739	Uncharacterized protein family UPF0029
V753_RS16450	COG1316	TRANSCRIPTIONal
V753_RS16455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
V753_RS16460	COG0438	transferase activity, transferring glycosyl groups
V753_RS16465	COG1215	transferase activity, transferring glycosyl groups
V753_RS16470	COG3206	protein involved in exopolysaccharide biosynthesis
V753_RS16475	COG3307	-O-antigen
V753_RS16480	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
V753_RS16485	COG0297	glycogen (starch) synthase activity
V753_RS16485	COG0438	transferase activity, transferring glycosyl groups
V753_RS16490	COG2244	polysaccharide biosynthetic process
V753_RS16500	COG0860	N-Acetylmuramoyl-L-alanine amidase
V753_RS16500	COG2247	cell wall binding repeat
V753_RS16505	COG2385	sporulation resulting in formation of a cellular spore
V753_RS16505	COG2247	cell wall binding repeat
V753_RS16515	COG1316	TRANSCRIPTIONal
V753_RS16520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
V753_RS16525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
V753_RS16530	COG1134	teichoic acid transport
V753_RS16535	COG1682	transport, permease protein
V753_RS16540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
V753_RS16550	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
V753_RS16555	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
V753_RS16560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
V753_RS16565	COG4193	domain, Protein
V753_RS16570	COG1482	cell wall glycoprotein biosynthetic process
V753_RS16575	COG0697	spore germination
V753_RS16580	COG0814	amino acid
V753_RS16590	COG1215	transferase activity, transferring glycosyl groups
V753_RS16595	COG2814	Major facilitator Superfamily
V753_RS16600	COG1316	TRANSCRIPTIONal
V753_RS16605	COG0561	phosphatase activity
V753_RS16610	COG2433	Pfam Transposase IS66
V753_RS16615	COG0791	NLP P60 protein
V753_RS16625	COG2843	Capsule synthesis protein
V753_RS16635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
V753_RS16640	COG0697	spore germination
V753_RS16645	COG0814	amino acid
V753_RS16655	COG1609	Transcriptional regulator
V753_RS16660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
V753_RS16670	COG1129	ABC transporter
V753_RS16675	COG1172	Belongs to the binding-protein-dependent transport system permease family
V753_RS16680	COG1879	ABC-type sugar transport system periplasmic component
V753_RS16685	COG3103	Sh3 type 3 domain protein
V753_RS16690	COG2249	NAD(P)H dehydrogenase (quinone) activity
V753_RS16695	COG3527	Alpha-acetolactate decarboxylase
V753_RS16700	COG0028	Belongs to the TPP enzyme family
V753_RS16705	COG0583	DNA-binding transcription factor activity
V753_RS16710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
V753_RS16725	COG5337	Spore coat protein CotH
V753_RS16735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
V753_RS16745	COG0405	Gamma-glutamyltransferase
V753_RS16750	COG1522	sequence-specific DNA binding
V753_RS16755	COG2059	Chromate
V753_RS16760	COG2059	Chromate
V753_RS16770	COG0655	NAD(P)H dehydrogenase (quinone) activity
V753_RS16775	COG0583	DNA-binding transcription factor activity
V753_RS16820	COG3878	Protein conserved in bacteria
V753_RS16825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
V753_RS16830	COG4464	protein tyrosine phosphatase activity
V753_RS16835	COG0489	protein tyrosine kinase activity
V753_RS16840	COG3944	biosynthesis protein
V753_RS16850	COG4715	Zinc finger, swim domain protein
V753_RS16855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
V753_RS16860	COG0561	phosphatase activity
V753_RS16865	COG1349	DNA-binding transcription factor activity
V753_RS16870	COG0629	single-stranded DNA binding
V753_RS16895	COG0457	Tetratricopeptide repeat
V753_RS16900	COG4786	Flagellar basal body rod
V753_RS16905	COG4786	Flagellar basal body rod
V753_RS16910	COG1077	Cell shape determining protein MreB Mrl
V753_RS16915	COG1609	Transcriptional regulator
V753_RS16920	COG1846	Transcriptional regulator
V753_RS16925	COG2814	Major facilitator Superfamily
V753_RS16930	COG1953	Uracil, thiamine, allantoin
V753_RS16935	COG0477	Major facilitator Superfamily
V753_RS16940	COG1335	isochorismatase
V753_RS16945	COG0004	ammonium transporteR
V753_RS16950	COG0347	Belongs to the P(II) protein family
V753_RS16955	COG0772	Belongs to the SEDS family
V753_RS16960	COG0671	phosphoesterase, PA-phosphatase related
V753_RS16970	COG0739	heme binding
V753_RS16975	COG1247	-acetyltransferase
V753_RS16990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
V753_RS17000	COG0726	polysaccharide deacetylase
V753_RS17010	COG1959	2 iron, 2 sulfur cluster binding
V753_RS17025	COG0831	urea catabolic process
V753_RS17030	COG3237	CsbD-like
V753_RS17035	COG1994	Peptidase M50
V753_RS17040	COG0457	Tetratricopeptide repeat
V753_RS17050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
V753_RS17060	COG2304	oxidoreductase activity
V753_RS17065	COG2304	oxidoreductase activity
V753_RS17070	COG2385	sporulation resulting in formation of a cellular spore
V753_RS17075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
V753_RS17085	COG4836	Membrane
V753_RS17155	COG0698	ribose 5-phosphate isomerase
V753_RS17160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
V753_RS17170	COG0009	L-threonylcarbamoyladenylate synthase
V753_RS17175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
V753_RS17195	COG2890	protein-(glutamine-N5) methyltransferase activity
V753_RS17200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
V753_RS17205	COG0346	lactoylglutathione lyase activity
V753_RS17210	COG0789	Transcriptional regulator
V753_RS17215	COG0679	Auxin Efflux Carrier
V753_RS17220	COG0281	malic enzyme
V753_RS17235	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
V753_RS17245	COG1494	fructose-1,6-bisphosphatase
V753_RS17250	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
V753_RS17260	COG0191	fructose-bisphosphate aldolase activity
V753_RS17265	COG2204	response regulator
V753_RS17270	COG4821	SIS domain
V753_RS17285	COG0247	lactate metabolic process
V753_RS17285	COG2181	nitrate reductase activity
V753_RS17290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
V753_RS17305	COG1132	(ABC) transporter
V753_RS17310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
V753_RS17320	COG2181	nitrate reductase activity
V753_RS17325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
V753_RS17330	COG1140	nitrate reductase beta subunit
V753_RS17335	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
V753_RS17340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
V753_RS17350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
V753_RS17355	COG2223	nitrite transmembrane transporter activity
V753_RS17365	COG4506	Protein conserved in bacteria
V753_RS17375	COG3391	amine dehydrogenase activity
V753_RS17380	COG3391	amine dehydrogenase activity
V753_RS17385	COG0457	Tetratricopeptide repeat
V753_RS17425	COG0010	Belongs to the arginase family
V753_RS17430	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
V753_RS17435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
V753_RS17450	COG1994	Peptidase M50
V753_RS17455	COG1942	4-Oxalocrotonate Tautomerase
V753_RS17460	COG1846	Transcriptional regulator
V753_RS17465	COG0531	amino acid
V753_RS17470	COG3465	dGTPase activity
V753_RS17475	COG1078	dGTPase activity
V753_RS17490	COG1695	Transcriptional regulator
V753_RS17500	COG1131	(ABC) transporter
V753_RS17505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
V753_RS17535	COG0583	DNA-binding transcription factor activity
V753_RS17540	COG2855	membrane
V753_RS17545	COG0280	phosphate acetyltransferase
V753_RS17555	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS17560	COG0436	Aminotransferase
V753_RS17590	COG2814	Major facilitator Superfamily
V753_RS17595	COG2814	Major facilitator Superfamily
V753_RS17600	COG0833	amino acid
V753_RS17605	COG4187	Peptidase family M20/M25/M40
V753_RS17610	COG1012	belongs to the aldehyde dehydrogenase family
V753_RS17615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
V753_RS17620	COG2205	protein histidine kinase activity
V753_RS17625	COG0745	RESPONSE REGULATOR receiver
V753_RS17640	COG1131	(ABC) transporter
V753_RS17645	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
V753_RS17650	COG1091	dTDP-4-dehydrorhamnose reductase activity
V753_RS17655	COG1088	dTDP-glucose 4,6-dehydratase activity
V753_RS17660	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
V753_RS17665	COG3980	spore coat polysaccharide biosynthesis protein
V753_RS17670	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
V753_RS17675	COG2089	acid synthase
V753_RS17680	COG0456	acetyltransferase
V753_RS17685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
V753_RS17690	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
V753_RS17695	COG0463	Glycosyl transferase, family 2
V753_RS17705	COG2363	Small membrane protein
V753_RS17710	COG2233	PERMEase
V753_RS17725	COG1216	Glycosyl transferase, family 2
V753_RS17740	COG1695	Transcriptional regulator
V753_RS17745	COG0351	phosphomethylpyrimidine kinase
V753_RS17755	COG1621	beta-fructofuranosidase activity
V753_RS17760	COG1263	PTS System
V753_RS17760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V753_RS17765	COG3711	transcriptional antiterminator
V753_RS17775	COG1404	Belongs to the peptidase S8 family
V753_RS17780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V753_RS17785	COG0778	Nitroreductase
V753_RS17790	COG0772	Belongs to the SEDS family
V753_RS17795	COG0454	-acetyltransferase
V753_RS17815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
V753_RS17820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
V753_RS17825	COG2261	transglycosylase associated protein
V753_RS17830	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
V753_RS17835	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
V753_RS17840	COG2246	polysaccharide biosynthetic process
V753_RS17845	COG1309	transcriptional regulator
V753_RS17855	COG2813	Specifically methylates the guanine in position
V753_RS17865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
V753_RS17870	COG2837	iron assimilation
V753_RS17890	COG0583	DNA-binding transcription factor activity
V753_RS17900	COG1346	cytolysis
V753_RS17905	COG4895	conserved protein (DUF2196)
V753_RS17910	COG0789	Transcriptional regulator
V753_RS17915	COG5504	Zn-dependent protease
V753_RS17920	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
V753_RS17925	COG0346	lactoylglutathione lyase activity
V753_RS17930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V753_RS17935	COG1404	Belongs to the peptidase S8 family
V753_RS17940	COG1442	glycosyl transferase family 8
V753_RS17945	COG1846	Transcriptional regulator
V753_RS17950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
V753_RS17955	COG2357	RelA SpoT domain protein
V753_RS17960	COG1575	Belongs to the MenA family. Type 1 subfamily
V753_RS17975	COG1696	Membrane protein involved in D-alanine export
V753_RS17985	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
V753_RS17990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
V753_RS17995	COG1486	melibiose metabolic process
V753_RS18000	COG1447	Phosphotransferase system cellobiose-specific component IIA
V753_RS18005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V753_RS18010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V753_RS18015	COG3711	transcriptional antiterminator
V753_RS18015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
V753_RS18025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V753_RS18030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V753_RS18040	COG0640	Transcriptional regulator
V753_RS18045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
V753_RS18050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V753_RS18055	COG1447	Phosphotransferase system cellobiose-specific component IIA
V753_RS18060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V753_RS18065	COG2723	6-phospho-beta-galactosidase activity
V753_RS18070	COG1940	carbohydrate kinase activity
V753_RS18075	COG1482	cell wall glycoprotein biosynthetic process
V753_RS18085	COG0753	catalase activity
V753_RS18090	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
V753_RS18095	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
V753_RS18100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
V753_RS18105	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
V753_RS18110	COG4988	ABC transporter
V753_RS18115	COG1294	oxidase, subunit
V753_RS18120	COG1271	oxidase subunit
V753_RS18125	COG3493	citrate carrier protein
V753_RS18130	COG0726	polysaccharide deacetylase
V753_RS18135	COG3842	ATPase activity
V753_RS18140	COG2508	Transcriptional regulator
V753_RS18145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V753_RS18155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
V753_RS18170	COG4894	glucomannan catabolic process
V753_RS18175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
V753_RS18180	COG0500	methyltransferase
V753_RS18185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
V753_RS18200	COG0753	catalase activity
V753_RS18200	COG0693	protein deglycase activity
V753_RS18205	COG2851	Citrate transporter
V753_RS18210	COG2273	Hydrolase Family 16
V753_RS18220	COG2270	Major facilitator Superfamily
V753_RS18225	COG0513	Belongs to the DEAD box helicase family
V753_RS18295	COG3209	COG3209 Rhs family protein
V753_RS18305	COG0697	spore germination
V753_RS18310	COG0589	response to stress
V753_RS18330	COG3507	Belongs to the glycosyl hydrolase 43 family
V753_RS18355	COG0010	Belongs to the arginase family
V753_RS18360	COG0833	amino acid
V753_RS18365	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
V753_RS18370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
V753_RS18380	COG2390	Transcriptional regulator
V753_RS18385	COG0561	phosphatase activity
V753_RS18415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V753_RS18420	COG5294	Protein conserved in bacteria
V753_RS18425	COG0577	efflux transmembrane transporter activity
V753_RS18430	COG1136	(ABC) transporter
V753_RS18435	COG2205	protein histidine kinase activity
V753_RS18440	COG0745	RESPONSE REGULATOR receiver
V753_RS18445	COG2205	protein histidine kinase activity
V753_RS18450	COG0745	RESPONSE REGULATOR receiver
V753_RS18475	COG0745	RESPONSE REGULATOR receiver
V753_RS18505	COG1082	Xylose isomerase domain protein TIM barrel
V753_RS18515	COG2814	Major facilitator Superfamily
V753_RS18545	COG1349	DNA-binding transcription factor activity
V753_RS18550	COG0667	Aldo Keto reductase
V753_RS18555	COG2814	Major facilitator Superfamily
V753_RS18570	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS18575	COG2197	response regulator
V753_RS18580	COG4585	Histidine kinase
V753_RS18585	COG3239	Fatty acid desaturase
V753_RS18590	COG1309	transcriptional regulator
V753_RS18595	COG1012	belongs to the aldehyde dehydrogenase family
V753_RS18600	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
V753_RS18610	COG0640	Transcriptional regulator
V753_RS18615	COG2814	Major facilitator Superfamily
V753_RS18620	COG1714	RDD family
V753_RS18630	COG0450	alkyl hydroperoxide reductase
V753_RS18635	COG3634	alkyl hydroperoxide reductase activity
V753_RS18640	COG1113	amino acid transport
V753_RS18650	COG2080	2 iron, 2 sulfur cluster binding
V753_RS18665	COG2068	MobA-Related Protein
V753_RS18670	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
V753_RS18710	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
V753_RS18715	COG0667	Aldo Keto reductase
V753_RS18720	COG0456	acetyltransferase
V753_RS18725	COG0457	Tetratricopeptide repeat
V753_RS18730	COG0010	Belongs to the arginase family
V753_RS18735	COG0833	amino acid
V753_RS18740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
V753_RS18745	COG5658	integral membrane protein
V753_RS18750	COG0640	Transcriptional regulator
V753_RS18755	COG3829	transcription factor binding
V753_RS18765	COG0488	(ABC) transporter
V753_RS18780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
V753_RS18785	COG5002	protein histidine kinase activity
V753_RS18795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
V753_RS18800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
V753_RS18805	COG4853	Protein conserved in bacteria
V753_RS18810	COG4863	YycH protein
V753_RS18815	COG5002	protein histidine kinase activity
V753_RS18820	COG0745	RESPONSE REGULATOR receiver
V753_RS18850	COG0346	lactoylglutathione lyase activity
V753_RS18855	COG0305	Participates in initiation and elongation during chromosome replication
V753_RS18870	COG3093	addiction module antidote protein HigA
V753_RS18890	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
V753_RS18895	COG0438	transferase activity, transferring glycosyl groups
V753_RS18915	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
V753_RS18920	COG4241	membrane
V753_RS18930	COG5577	PFAM Coat F domain
V753_RS18935	COG1733	regulation of RNA biosynthetic process
V753_RS18945	COG0697	spore germination
V753_RS18950	COG1621	beta-fructofuranosidase activity
V753_RS18955	COG1621	beta-fructofuranosidase activity
V753_RS18965	COG2318	DinB family
V753_RS18970	COG2211	Major facilitator Superfamily
V753_RS18980	COG0778	Nitroreductase
V753_RS18985	COG1846	Transcriptional regulator
V753_RS18990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V753_RS18995	COG1846	Transcriptional regulator
V753_RS19000	COG2153	protein acetylation
V753_RS19010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
V753_RS19015	COG0583	DNA-binding transcription factor activity
V753_RS19020	COG1028	Short-chain dehydrogenase reductase Sdr
V753_RS19035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V753_RS19040	COG0697	spore germination
V753_RS19045	COG3621	Patatin-like phospholipase
V753_RS19050	COG1331	Highly conserved protein containing a thioredoxin domain
V753_RS19055	COG1266	CAAX protease self-immunity
V753_RS19060	COG2814	Major facilitator Superfamily
V753_RS19060	COG0477	Major facilitator Superfamily
V753_RS19065	COG0346	lactoylglutathione lyase activity
V753_RS19070	COG1609	Transcriptional regulator
V753_RS19075	COG0708	Exodeoxyribonuclease III
V753_RS19080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
V753_RS19085	COG2169	Transcriptional regulator
V753_RS19095	COG0629	single-stranded DNA binding
V753_RS19105	COG0012	GTP binding
V753_RS19110	COG0243	molybdopterin cofactor binding
V753_RS19115	COG4481	Protein conserved in bacteria
V753_RS19120	COG3949	Membrane
V753_RS19135	COG1475	DNA binding
V753_RS19140	COG1192	Involved in chromosome partitioning
V753_RS19165	COG1847	R3H domain protein
V753_RS19170	COG0706	membrane insertase activity