locus-tag	class	description
GG619_RS00010	COG0592	DNA-directed DNA polymerase activity
GG619_RS00015	COG2501	S4 domain
GG619_RS00030	COG0187	DNA topoisomerase II activity
GG619_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GG619_RS00070	COG0517	IMP dehydrogenase activity
GG619_RS00070	COG0516	GMP reductase activity
GG619_RS00075	COG1686	Belongs to the peptidase S11 family
GG619_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
GG619_RS00105	COG1428	Deoxynucleoside kinase
GG619_RS00110	COG1428	Deoxynucleoside kinase
GG619_RS00115	COG1388	LysM domain
GG619_RS00115	COG3858	chitin binding
GG619_RS00120	COG1335	isochorismatase
GG619_RS00125	COG0590	tRNA wobble adenosine to inosine editing
GG619_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GG619_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GG619_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GG619_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GG619_RS00195	COG3853	Toxic anion resistance protein (TelA)
GG619_RS00200	COG1982	Orn Lys Arg decarboxylase major
GG619_RS00210	COG3870	Protein conserved in bacteria
GG619_RS00215	COG1728	Protein conserved in bacteria
GG619_RS00220	COG0470	DNA polymerase III
GG619_RS00225	COG1774	PSP1 C-terminal conserved region
GG619_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GG619_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GG619_RS00250	COG2002	toxin-antitoxin pair type II binding
GG619_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GG619_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GG619_RS00260	COG0084	hydrolase, TatD family'
GG619_RS00265	COG3583	domain protein
GG619_RS00265	COG3584	3D domain protein
GG619_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GG619_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GG619_RS00285	COG4466	Protein conserved in bacteria
GG619_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GG619_RS00305	COG0251	oxidation-reduction process
GG619_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GG619_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GG619_RS00345	COG2002	toxin-antitoxin pair type II binding
GG619_RS00350	COG2244	polysaccharide biosynthetic process
GG619_RS00355	COG3956	TIGRFAM MazG family protein
GG619_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GG619_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GG619_RS00380	COG1098	S1 RNA binding domain
GG619_RS00395	COG2208	phosphoserine phosphatase activity
GG619_RS00400	COG2304	oxidoreductase activity
GG619_RS00405	COG0515	serine threonine protein kinase
GG619_RS00410	COG0037	tRNA processing
GG619_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GG619_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GG619_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GG619_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GG619_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GG619_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
GG619_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GG619_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GG619_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GG619_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GG619_RS00475	COG1396	sequence-specific DNA binding
GG619_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GG619_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GG619_RS00565	COG4463	regulation of RNA biosynthetic process
GG619_RS00570	COG3880	PFAM UvrB UvrC protein
GG619_RS00580	COG0542	response to heat
GG619_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GG619_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GG619_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
GG619_RS00615	COG1045	serine acetyltransferase
GG619_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GG619_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GG619_RS00635	COG3688	RNA-binding protein containing a PIN domain
GG619_RS00640	COG1595	DNA-templated transcription, initiation
GG619_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GG619_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
GG619_RS00680	COG2813	Specifically methylates the guanine in position
GG619_RS00695	COG1358	cellular component organization or biogenesis
GG619_RS00720	COG0596	Alpha beta hydrolase
GG619_RS00830	COG0201	protein transport
GG619_RS00840	COG0024	Methionine aminopeptidase
GG619_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GG619_RS00880	COG1122	ATPase activity
GG619_RS00885	COG1122	ATPase activity
GG619_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GG619_RS00910	COG2226	methyltransferase
GG619_RS00915	COG2318	DinB family
GG619_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
GG619_RS00930	COG0489	protein tyrosine kinase activity
GG619_RS00940	COG2194	sulfuric ester hydrolase activity
GG619_RS00945	COG0726	polysaccharide deacetylase
GG619_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GG619_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
GG619_RS01030	COG0385	Bile acid
GG619_RS01035	COG2819	hydrolase of the alpha beta superfamily
GG619_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GG619_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GG619_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GG619_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GG619_RS01055	COG2207	Transcriptional regulator
GG619_RS01060	COG3876	Protein conserved in bacteria
GG619_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
GG619_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GG619_RS01075	COG1263	PTS System
GG619_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GG619_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GG619_RS01090	COG1683	Conserved Protein
GG619_RS01120	COG1595	DNA-templated transcription, initiation
GG619_RS01125	COG5662	AntiSigma factor
GG619_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GG619_RS01135	COG4856	YbbR-like protein
GG619_RS01190	COG1346	cytolysis
GG619_RS01195	COG1380	Effector of murein hydrolase LrgA
GG619_RS01200	COG1846	Transcriptional regulator
GG619_RS01205	COG1113	amino acid transport
GG619_RS01210	COG1011	Hydrolase
GG619_RS01215	COG4585	Histidine kinase
GG619_RS01220	COG2197	response regulator
GG619_RS01225	COG1131	(ABC) transporter
GG619_RS01265	COG0531	amino acid
GG619_RS01270	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GG619_RS01285	COG0584	glycerophosphoryl diester phosphodiesterase
GG619_RS01290	COG2271	Major facilitator Superfamily
GG619_RS01300	COG2368	4-hydroxyphenylacetate
GG619_RS01310	COG3409	Peptidoglycan-binding domain 1 protein
GG619_RS01325	COG0371	Dehydrogenase
GG619_RS01335	COG1183	phosphatidylcholine synthase activity
GG619_RS01340	COG0586	Pfam SNARE associated Golgi protein
GG619_RS01345	COG0688	phosphatidylethanolamine metabolic process
GG619_RS01360	COG1301	dicarboxylic acid transport
GG619_RS01365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GG619_RS01370	COG0833	amino acid
GG619_RS01375	COG2040	homocysteine
GG619_RS01380	COG1115	amino acid carrier protein
GG619_RS01385	COG2066	Belongs to the glutaminase family
GG619_RS01390	COG4191	Histidine kinase
GG619_RS01395	COG0784	Response regulator, receiver
GG619_RS01415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GG619_RS01420	COG0778	Nitroreductase
GG619_RS01425	COG0346	lactoylglutathione lyase activity
GG619_RS01430	COG2259	Doxx family
GG619_RS01435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GG619_RS01445	COG3773	Cell wall hydrolase
GG619_RS01450	COG3540	Alkaline phosphatase
GG619_RS01455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GG619_RS01460	COG0805	protein transport
GG619_RS01470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GG619_RS01475	COG0477	Major facilitator Superfamily
GG619_RS01480	COG1309	transcriptional regulator
GG619_RS01485	COG0252	asparaginase activity
GG619_RS01490	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GG619_RS01495	COG3012	SEC-C Motif Domain Protein
GG619_RS01495	COG1405	negative regulation of cell septum assembly
GG619_RS01500	COG0667	Aldo Keto reductase
GG619_RS01510	COG1595	DNA-templated transcription, initiation
GG619_RS01515	COG1595	DNA-templated transcription, initiation
GG619_RS01520	COG1876	peptidase activity
GG619_RS01525	COG0457	Tetratricopeptide repeat
GG619_RS01530	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS01555	COG0366	Alpha amylase catalytic
GG619_RS01560	COG0803	Belongs to the bacterial solute-binding protein 9 family
GG619_RS01565	COG1121	(ABC) transporter
GG619_RS01570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GG619_RS01575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GG619_RS01580	COG2310	stress, protein
GG619_RS01585	COG2310	stress, protein
GG619_RS01590	COG2310	stress, protein
GG619_RS01595	COG0861	Integral membrane protein TerC family
GG619_RS01605	COG3853	Toxic anion resistance protein (TelA)
GG619_RS01610	COG0477	Major facilitator Superfamily
GG619_RS01615	COG4175	Glycine betaine
GG619_RS01615	COG0517	IMP dehydrogenase activity
GG619_RS01620	COG4176	ABC-type proline glycine betaine transport system permease component
GG619_RS01625	COG2113	Glycine betaine
GG619_RS01630	COG1473	amidohydrolase
GG619_RS01635	COG1288	antiporter activity
GG619_RS01645	COG0366	Alpha amylase catalytic
GG619_RS01655	COG2814	Major facilitator Superfamily
GG619_RS01660	COG1846	Transcriptional regulator
GG619_RS01665	COG1280	lysine exporter protein (LysE YggA)
GG619_RS01670	COG3403	YqcI/YcgG family
GG619_RS01675	COG1113	amino acid transport
GG619_RS01680	COG3665	Urea carboxylase-associated protein
GG619_RS01695	COG1660	Displays ATPase and GTPase activities
GG619_RS01700	COG1082	Xylose isomerase domain protein TIM barrel
GG619_RS01705	COG2271	Major facilitator Superfamily
GG619_RS01710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GG619_RS01715	COG3458	cephalosporin-C deacetylase activity
GG619_RS01720	COG3541	Predicted nucleotidyltransferase
GG619_RS01725	COG0506	proline dehydrogenase activity
GG619_RS01730	COG1012	belongs to the aldehyde dehydrogenase family
GG619_RS01735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GG619_RS01740	COG2508	Transcriptional regulator
GG619_RS01750	COG1587	Uroporphyrinogen-III synthase
GG619_RS01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GG619_RS01755	COG2146	nitrite reductase [NAD(P)H] activity
GG619_RS01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GG619_RS01765	COG0243	molybdopterin cofactor binding
GG619_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GG619_RS01775	COG2223	nitrite transmembrane transporter activity
GG619_RS01780	COG0523	cobalamin synthesis protein
GG619_RS01785	COG1063	alcohol dehydrogenase
GG619_RS01790	COG1714	RDD family
GG619_RS01800	COG2723	6-phospho-beta-galactosidase activity
GG619_RS01810	COG3209	COG3209 Rhs family protein
GG619_RS01815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GG619_RS01820	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GG619_RS01825	COG1733	regulation of RNA biosynthetic process
GG619_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS01845	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GG619_RS01860	COG0697	spore germination
GG619_RS01865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GG619_RS01875	COG2364	Membrane
GG619_RS01880	COG1126	abc transporter atp-binding protein
GG619_RS01885	COG0765	amino acid transport
GG619_RS01890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GG619_RS01895	COG0583	DNA-binding transcription factor activity
GG619_RS01900	COG0163	prenyltransferase activity
GG619_RS01905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GG619_RS01920	COG3104	oligopeptide transport
GG619_RS01925	COG5434	Belongs to the glycosyl hydrolase 28 family
GG619_RS01935	COG0697	spore germination
GG619_RS01945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GG619_RS01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GG619_RS01955	COG0456	acetyltransferase
GG619_RS01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GG619_RS01965	COG0765	amino acid transport
GG619_RS01970	COG1126	abc transporter atp-binding protein
GG619_RS01975	COG1473	amidohydrolase
GG619_RS01980	COG2079	MmgE PrpD family protein
GG619_RS01985	COG1136	(ABC) transporter
GG619_RS01990	COG0577	efflux transmembrane transporter activity
GG619_RS01995	COG0745	RESPONSE REGULATOR receiver
GG619_RS02000	COG3850	Histidine kinase
GG619_RS02000	COG5002	protein histidine kinase activity
GG619_RS02005	COG0457	Tetratricopeptide repeat
GG619_RS02020	COG0527	aspartate kinase activity
GG619_RS02025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GG619_RS02030	COG4605	iron ion homeostasis
GG619_RS02035	COG4604	ABC transporter, ATP-binding protein
GG619_RS02040	COG4607	ABC-type enterochelin transport system periplasmic component
GG619_RS02045	COG2814	Major facilitator Superfamily
GG619_RS02050	COG1309	transcriptional regulator
GG619_RS02055	COG0778	Nitroreductase
GG619_RS02060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GG619_RS02065	COG0640	Transcriptional regulator
GG619_RS02070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GG619_RS02075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GG619_RS02080	COG1012	belongs to the aldehyde dehydrogenase family
GG619_RS02085	COG4975	Glucose uptake
GG619_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS02095	COG4549	nuclear export factor GLE1
GG619_RS02100	COG2372	response to copper ion
GG619_RS02100	COG1276	copper resistance
GG619_RS02105	COG1349	DNA-binding transcription factor activity
GG619_RS02115	COG2213	PTS system mannitol-specific
GG619_RS02120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GG619_RS02130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GG619_RS02140	COG0561	phosphatase activity
GG619_RS02150	COG1914	H( )-stimulated, divalent metal cation uptake system
GG619_RS02160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GG619_RS02165	COG1984	allophanate hydrolase subunit 2
GG619_RS02170	COG1414	Transcriptional regulator
GG619_RS02175	COG2755	lipolytic protein G-D-S-L family
GG619_RS02185	COG2329	Antibiotic biosynthesis monooxygenase
GG619_RS02190	COG0768	penicillin binding
GG619_RS02195	COG4989	oxidoreductase activity
GG619_RS02200	COG3711	transcriptional antiterminator
GG619_RS02205	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS02215	COG1917	Cupin 2, conserved barrel domain protein
GG619_RS02220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GG619_RS02225	COG3871	stress protein (general stress protein 26)
GG619_RS02235	COG2814	Major facilitator Superfamily
GG619_RS02240	COG1522	sequence-specific DNA binding
GG619_RS02245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GG619_RS02245	COG0551	DNA topoisomerase type I activity
GG619_RS02250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GG619_RS02255	COG3706	GGDEF domain
GG619_RS02260	COG5298	Protein conserved in bacteria
GG619_RS02265	COG1215	transferase activity, transferring glycosyl groups
GG619_RS02275	COG0531	amino acid
GG619_RS02280	COG0494	nUDIX hydrolase
GG619_RS02285	COG0028	Belongs to the TPP enzyme family
GG619_RS02340	COG1914	H( )-stimulated, divalent metal cation uptake system
GG619_RS02350	COG4876	unkown
GG619_RS02360	COG2076	Multidrug Resistance protein
GG619_RS02365	COG2217	Heavy metal translocating P-type atpase
GG619_RS02370	COG3729	General stress protein
GG619_RS02375	COG0662	Cupin 2, conserved barrel domain protein
GG619_RS02380	COG2329	Antibiotic biosynthesis monooxygenase
GG619_RS02385	COG3546	catalase activity
GG619_RS02390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GG619_RS02395	COG3290	protein histidine kinase activity
GG619_RS02400	COG4565	transcriptional regulatory protein
GG619_RS02405	COG1301	dicarboxylic acid transport
GG619_RS02410	COG0628	permease
GG619_RS02415	COG1131	(ABC) transporter
GG619_RS02420	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GG619_RS02430	COG1960	acyl-CoA dehydrogenase activity
GG619_RS02445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GG619_RS02450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GG619_RS02460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GG619_RS02470	COG0513	Belongs to the DEAD box helicase family
GG619_RS02475	COG3402	PFAM membrane-flanked domain
GG619_RS02480	COG3428	Bacterial PH domain
GG619_RS02485	COG0705	Rhomboid family
GG619_RS02495	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GG619_RS02500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GG619_RS02505	COG0864	Transcriptional regulator
GG619_RS02510	COG2337	Toxic component of a toxin-antitoxin (TA) module
GG619_RS02515	COG1366	Belongs to the anti-sigma-factor antagonist family
GG619_RS02520	COG1366	Belongs to the anti-sigma-factor antagonist family
GG619_RS02525	COG2172	sigma factor antagonist activity
GG619_RS02530	COG2208	phosphoserine phosphatase activity
GG619_RS02535	COG1366	Belongs to the anti-sigma-factor antagonist family
GG619_RS02545	COG1191	sigma factor activity
GG619_RS02550	COG2208	phosphoserine phosphatase activity
GG619_RS02555	COG2183	response to ionizing radiation
GG619_RS02605	COG2249	NAD(P)H dehydrogenase (quinone) activity
GG619_RS02615	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GG619_RS02620	COG1522	sequence-specific DNA binding
GG619_RS02640	COG0477	Major facilitator Superfamily
GG619_RS02655	COG2030	dehydratase
GG619_RS02665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GG619_RS02670	COG1959	2 iron, 2 sulfur cluster binding
GG619_RS02675	COG2910	NAD(P)H-binding
GG619_RS02680	COG1278	Cold shock
GG619_RS02685	COG1329	Transcriptional regulator
GG619_RS02690	COG1794	racemase activity, acting on amino acids and derivatives
GG619_RS02705	COG3621	Patatin-like phospholipase
GG619_RS02715	COG0662	Cupin 2, conserved barrel domain protein
GG619_RS02730	COG0277	FAD linked oxidase domain protein
GG619_RS02755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GG619_RS02790	COG0351	phosphomethylpyrimidine kinase
GG619_RS02805	COG1064	alcohol dehydrogenase
GG619_RS02810	COG0789	Transcriptional regulator
GG619_RS02820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GG619_RS02835	COG2814	Major facilitator Superfamily
GG619_RS02840	COG1309	transcriptional regulator
GG619_RS02845	COG0697	spore germination
GG619_RS02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GG619_RS02855	COG5577	PFAM Coat F domain
GG619_RS02865	COG1063	alcohol dehydrogenase
GG619_RS02870	COG5577	PFAM Coat F domain
GG619_RS02880	COG4585	Histidine kinase
GG619_RS02885	COG2197	response regulator
GG619_RS02890	COG2409	Drug exporters of the RND superfamily
GG619_RS02895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GG619_RS02900	COG0488	(ABC) transporter
GG619_RS02905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GG619_RS02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GG619_RS02920	COG2814	Major facilitator Superfamily
GG619_RS02925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GG619_RS02935	COG0730	response to heat
GG619_RS02940	COG0456	acetyltransferase
GG619_RS02950	COG1051	belongs to the nudix hydrolase family
GG619_RS02955	COG2226	methyltransferase
GG619_RS02960	COG0473	3-isopropylmalate dehydrogenase activity
GG619_RS02965	COG1802	Transcriptional regulator
GG619_RS02970	COG1819	glycosyl
GG619_RS02985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GG619_RS02990	COG1388	LysM domain
GG619_RS02995	COG2814	Major facilitator Superfamily
GG619_RS03000	COG2188	Transcriptional regulator
GG619_RS03005	COG2186	Transcriptional regulator
GG619_RS03010	COG2807	transmembrane transport
GG619_RS03015	COG2076	Multidrug Resistance protein
GG619_RS03020	COG2076	Multidrug Resistance protein
GG619_RS03025	COG1309	transcriptional regulator
GG619_RS03030	COG0531	amino acid
GG619_RS03040	COG3832	glyoxalase III activity
GG619_RS03045	COG0604	alcohol dehydrogenase
GG619_RS03050	COG2814	Major facilitator Superfamily
GG619_RS03090	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GG619_RS03095	COG0802	atpase or kinase
GG619_RS03100	COG1214	PFAM Peptidase M22, glycoprotease
GG619_RS03105	COG0456	acetyltransferase
GG619_RS03110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GG619_RS03115	COG0488	(ABC) transporter
GG619_RS03130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GG619_RS03135	COG0805	protein transport
GG619_RS03145	COG1266	CAAX protease self-immunity
GG619_RS03165	COG0457	Tetratricopeptide repeat
GG619_RS03170	COG1063	alcohol dehydrogenase
GG619_RS03175	COG2211	Major facilitator Superfamily
GG619_RS03180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GG619_RS03190	COG1842	Phage shock protein A
GG619_RS03195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GG619_RS03200	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GG619_RS03205	COG4260	virion core protein, lumpy skin disease virus
GG619_RS03210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GG619_RS03210	COG2755	lipolytic protein G-D-S-L family
GG619_RS03220	COG1595	DNA-templated transcription, initiation
GG619_RS03225	COG1063	alcohol dehydrogenase
GG619_RS03230	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GG619_RS03235	COG0823	Involved in the tonB-independent uptake of proteins
GG619_RS03245	COG2132	Multicopper oxidase
GG619_RS03250	COG1113	amino acid transport
GG619_RS03255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GG619_RS03260	COG0714	Associated with various cellular activities
GG619_RS03265	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GG619_RS03270	COG1305	Transglutaminase-like
GG619_RS03305	COG2252	PERMEase
GG619_RS03310	COG3064	Membrane
GG619_RS03330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GG619_RS03335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GG619_RS03340	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GG619_RS03345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GG619_RS03350	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GG619_RS03365	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GG619_RS03375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GG619_RS03380	COG0138	bifunctional purine biosynthesis protein purh
GG619_RS03385	COG0151	Belongs to the GarS family
GG619_RS03395	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GG619_RS03400	COG1470	cell adhesion involved in biofilm formation
GG619_RS03405	COG4496	protein, YerC YecD
GG619_RS03410	COG0069	glutamate synthase activity
GG619_RS03425	COG0210	DNA helicase
GG619_RS03435	COG4851	CamS sex pheromone cAM373 precursor
GG619_RS03440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GG619_RS03445	COG1285	pathogenesis
GG619_RS03450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GG619_RS03470	COG1309	transcriptional regulator
GG619_RS03475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GG619_RS03480	COG1597	lipid kinase activity
GG619_RS03485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GG619_RS03495	COG1131	(ABC) transporter
GG619_RS03520	COG5444	nuclease activity
GG619_RS03540	COG5444	nuclease activity
GG619_RS03570	COG3546	catalase activity
GG619_RS03575	COG0454	-acetyltransferase
GG619_RS03585	COG2323	membrane
GG619_RS03590	COG2329	Antibiotic biosynthesis monooxygenase
GG619_RS03595	COG0346	lactoylglutathione lyase activity
GG619_RS03600	COG1366	Belongs to the anti-sigma-factor antagonist family
GG619_RS03605	COG5583	Uncharacterized small protein (DUF2292)
GG619_RS03610	COG0196	riboflavin kinase activity
GG619_RS03615	COG0670	Belongs to the BI1 family
GG619_RS03625	COG1846	Transcriptional regulator
GG619_RS03630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GG619_RS03640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GG619_RS03640	COG2124	cytochrome p450
GG619_RS03645	COG1368	sulfuric ester hydrolase activity
GG619_RS03650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GG619_RS03655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GG619_RS03660	COG1442	glycosyl transferase family 8
GG619_RS03665	COG1216	Glycosyl transferase, family 2
GG619_RS03670	COG1442	glycosyl transferase family 8
GG619_RS03675	COG2223	nitrite transmembrane transporter activity
GG619_RS03680	COG0531	amino acid
GG619_RS03685	COG1012	belongs to the aldehyde dehydrogenase family
GG619_RS03690	COG0840	transmembrane signaling receptor activity
GG619_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS03700	COG0457	Tetratricopeptide repeat
GG619_RS03700	COG0463	Glycosyl transferase, family 2
GG619_RS03705	COG0488	(ABC) transporter
GG619_RS03710	COG0789	Transcriptional regulator
GG619_RS03715	COG2814	Major facilitator Superfamily
GG619_RS03720	COG0488	(ABC) transporter
GG619_RS03725	COG0513	Belongs to the DEAD box helicase family
GG619_RS03730	COG0456	acetyltransferase
GG619_RS03735	COG2130	NADP-dependent
GG619_RS03750	COG3866	Pectate lyase
GG619_RS03755	COG0471	metal ion transport
GG619_RS03770	COG2972	Histidine kinase
GG619_RS03770	COG0745	RESPONSE REGULATOR receiver
GG619_RS03775	COG3279	Response regulator of the LytR AlgR family
GG619_RS03785	COG3764	Sortase (surface protein transpeptidase)
GG619_RS03790	COG3290	protein histidine kinase activity
GG619_RS03795	COG4565	transcriptional regulatory protein
GG619_RS03800	COG3181	Tripartite tricarboxylate transporter family receptor
GG619_RS03805	COG2851	Citrate transporter
GG619_RS03810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GG619_RS03815	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GG619_RS03825	COG2258	MOSC domain
GG619_RS03845	COG0024	Methionine aminopeptidase
GG619_RS03850	COG1263	PTS System
GG619_RS03850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GG619_RS03860	COG1368	sulfuric ester hydrolase activity
GG619_RS03870	COG0071	Belongs to the small heat shock protein (HSP20) family
GG619_RS03885	COG1263	PTS System
GG619_RS03885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GG619_RS03890	COG0366	Alpha amylase catalytic
GG619_RS03895	COG2188	Transcriptional regulator
GG619_RS03900	COG0778	Nitroreductase
GG619_RS03915	COG0737	Belongs to the 5'-nucleotidase family
GG619_RS03920	COG0693	protein deglycase activity
GG619_RS03925	COG1609	Transcriptional regulator
GG619_RS03940	COG2814	Major facilitator Superfamily
GG619_RS03950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GG619_RS03955	COG4980	gas vesicle protein
GG619_RS03960	COG1295	ribonuclease BN
GG619_RS03970	COG0477	Major facilitator Superfamily
GG619_RS03975	COG0387	Pfam Sodium calcium exchanger
GG619_RS03985	COG0668	transmembrane transport
GG619_RS03990	COG0535	radical SAM domain protein
GG619_RS04000	COG0726	polysaccharide deacetylase
GG619_RS04005	COG2084	Dehydrogenase
GG619_RS04015	COG0598	Magnesium transport protein CorA
GG619_RS04020	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GG619_RS04025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GG619_RS04035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GG619_RS04040	COG4637	Psort location Cytoplasmic, score
GG619_RS04045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GG619_RS04050	COG0022	dehydrogenase e1 component
GG619_RS04055	COG0508	dehydrogenase complex catalyzes the overall conversion of
GG619_RS04060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GG619_RS04065	COG3284	Transcriptional regulator
GG619_RS04075	COG1486	melibiose metabolic process
GG619_RS04080	COG1737	Transcriptional regulator
GG619_RS04085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GG619_RS04085	COG1263	PTS System
GG619_RS04090	COG1132	(ABC) transporter
GG619_RS04095	COG1132	(ABC) transporter
GG619_RS04100	COG2259	Doxx family
GG619_RS04105	COG2514	catechol 2,3-dioxygenase activity
GG619_RS04115	COG1695	Transcriptional regulator
GG619_RS04120	COG2249	NAD(P)H dehydrogenase (quinone) activity
GG619_RS04125	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GG619_RS04135	COG0574	Belongs to the PEP-utilizing enzyme family
GG619_RS04135	COG3848	Pyruvate phosphate dikinase
GG619_RS04140	COG2732	(Barnase) inhibitor
GG619_RS04145	COG2318	DinB family
GG619_RS04150	COG2814	Major facilitator Superfamily
GG619_RS04155	COG1846	Transcriptional regulator
GG619_RS04160	COG0392	lysyltransferase activity
GG619_RS04160	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GG619_RS04165	COG0384	phenazine biosynthesis protein PhzF
GG619_RS04170	COG0778	Nitroreductase
GG619_RS04185	COG1090	epimerase
GG619_RS04200	COG2814	Major facilitator Superfamily
GG619_RS04210	COG3591	Belongs to the peptidase S1B family
GG619_RS04225	COG3103	Sh3 type 3 domain protein
GG619_RS04230	COG5658	integral membrane protein
GG619_RS04235	COG0596	Alpha beta hydrolase
GG619_RS04240	COG0463	Glycosyl transferase, family 2
GG619_RS04245	COG4485	Bacterial membrane protein, YfhO
GG619_RS04250	COG1988	membrane-bound metal-dependent
GG619_RS04255	COG1194	a g-specific adenine glycosylase
GG619_RS04265	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS04285	COG1132	(ABC) transporter
GG619_RS04290	COG4129	membrane
GG619_RS04300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GG619_RS04305	COG0735	belongs to the Fur family
GG619_RS04415	COG1757	Na H antiporter
GG619_RS04420	COG3340	Belongs to the peptidase S51 family
GG619_RS04430	COG0277	FAD linked oxidase domain protein
GG619_RS04440	COG0747	negative chemotaxis
GG619_RS04445	COG0601	transmembrane transport
GG619_RS04450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GG619_RS04455	COG0444	Belongs to the ABC transporter superfamily
GG619_RS04460	COG4608	Belongs to the ABC transporter superfamily
GG619_RS04465	COG0753	catalase activity
GG619_RS04475	COG1116	anion transmembrane transporter activity
GG619_RS04480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GG619_RS04485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GG619_RS04505	COG1476	TRANSCRIPTIONal
GG619_RS04515	COG3382	B3 4 domain protein
GG619_RS04520	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GG619_RS04530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GG619_RS04535	COG0789	Transcriptional regulator
GG619_RS04540	COG1664	Polymer-forming cytoskeletal
GG619_RS04545	COG1664	Polymer-forming cytoskeletal
GG619_RS04550	COG2766	serine protein kinase
GG619_RS04560	COG1846	Transcriptional regulator
GG619_RS04565	COG1566	PFAM secretion protein HlyD family protein
GG619_RS04570	COG2814	Major facilitator Superfamily
GG619_RS04575	COG0655	NAD(P)H dehydrogenase (quinone) activity
GG619_RS04590	COG1725	Transcriptional regulator
GG619_RS04595	COG1131	(ABC) transporter
GG619_RS04600	COG1131	(ABC) transporter
GG619_RS04605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GG619_RS04610	COG1278	Cold shock
GG619_RS04615	COG1464	Belongs to the NlpA lipoprotein family
GG619_RS04620	COG3706	GGDEF domain
GG619_RS04625	COG1823	symporter activity
GG619_RS04645	COG5577	PFAM Coat F domain
GG619_RS04650	COG0737	Belongs to the 5'-nucleotidase family
GG619_RS04650	COG4085	toxin activity
GG619_RS04650	COG1525	nuclease
GG619_RS04655	COG3764	Sortase (surface protein transpeptidase)
GG619_RS04660	COG0564	pseudouridine synthase activity
GG619_RS04670	COG0517	IMP dehydrogenase activity
GG619_RS04675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GG619_RS04680	COG3153	acetyltransferase
GG619_RS04680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GG619_RS04685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GG619_RS04690	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GG619_RS04695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GG619_RS04705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GG619_RS04710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GG619_RS04715	COG4585	Histidine kinase
GG619_RS04715	COG2203	Gaf domain
GG619_RS04720	COG2197	response regulator
GG619_RS04725	COG0431	NADPH-dependent FMN reductase
GG619_RS04740	COG1388	LysM domain
GG619_RS04740	COG0791	NLP P60 protein
GG619_RS04745	COG1959	2 iron, 2 sulfur cluster binding
GG619_RS04750	COG0668	transmembrane transport
GG619_RS04755	COG2719	SpoVR family
GG619_RS04760	COG1785	Belongs to the alkaline phosphatase family
GG619_RS04765	COG1388	LysM domain
GG619_RS04765	COG0791	NLP P60 protein
GG619_RS04770	COG0583	DNA-binding transcription factor activity
GG619_RS04775	COG0372	Belongs to the citrate synthase family
GG619_RS04780	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS04785	COG0531	amino acid
GG619_RS04790	COG0733	neurotransmitter:sodium symporter activity
GG619_RS04805	COG1595	DNA-templated transcription, initiation
GG619_RS04810	COG0204	Acyl-transferase
GG619_RS04815	COG1253	flavin adenine dinucleotide binding
GG619_RS04820	COG0789	Transcriptional regulator
GG619_RS04825	COG0436	Aminotransferase
GG619_RS04830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GG619_RS04835	COG1253	flavin adenine dinucleotide binding
GG619_RS04840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GG619_RS04845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GG619_RS04850	COG0584	glycerophosphoryl diester phosphodiesterase
GG619_RS04860	COG0668	transmembrane transport
GG619_RS04865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GG619_RS04870	COG0726	polysaccharide deacetylase
GG619_RS04875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GG619_RS04880	COG3226	Transcriptional regulator
GG619_RS04890	COG0589	response to stress
GG619_RS04895	COG1132	(ABC) transporter
GG619_RS04900	COG1132	(ABC) transporter
GG619_RS04905	COG0702	epimerase
GG619_RS04920	COG0189	ligase activity
GG619_RS04925	COG0189	ligase activity
GG619_RS04940	COG4335	DNA alkylation repair
GG619_RS04945	COG0561	phosphatase activity
GG619_RS04950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GG619_RS04960	COG0475	glutathione-regulated potassium exporter activity
GG619_RS04965	COG0490	domain, Protein
GG619_RS04975	COG1024	Enoyl-CoA hydratase
GG619_RS04985	COG4152	abc transporter atp-binding protein
GG619_RS04990	COG1668	transmembrane transport
GG619_RS04995	COG0420	3'-5' exonuclease activity
GG619_RS05000	COG4717	serine-type aminopeptidase activity
GG619_RS05015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GG619_RS05050	COG4980	gas vesicle protein
GG619_RS05065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GG619_RS05070	COG0537	adenosine 5'-monophosphoramidase activity
GG619_RS05075	COG1131	(ABC) transporter
GG619_RS05080	COG4473	ABC transporter
GG619_RS05090	COG1473	amidohydrolase
GG619_RS05095	COG3069	C4-dicarboxylate transmembrane transporter activity
GG619_RS05100	COG2329	Antibiotic biosynthesis monooxygenase
GG619_RS05105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GG619_RS05115	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GG619_RS05120	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GG619_RS05125	COG1309	transcriptional regulator
GG619_RS05130	COG1511	domain protein
GG619_RS05135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GG619_RS05145	COG1363	Peptidase, m42
GG619_RS05150	COG1301	dicarboxylic acid transport
GG619_RS05160	COG1234	tRNA 3'-trailer cleavage
GG619_RS05165	COG0095	Lipoate-protein ligase
GG619_RS05170	COG0702	epimerase
GG619_RS05175	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS05185	COG0501	Belongs to the peptidase M48B family
GG619_RS05190	COG1404	Belongs to the peptidase S8 family
GG619_RS05200	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GG619_RS05205	COG0406	alpha-ribazole phosphatase activity
GG619_RS05210	COG0183	Belongs to the thiolase family
GG619_RS05215	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS05220	COG1268	BioY protein
GG619_RS05225	COG0840	transmembrane signaling receptor activity
GG619_RS05230	COG0723	plastoquinol--plastocyanin reductase activity
GG619_RS05230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GG619_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS05245	COG4903	ComK protein
GG619_RS05255	COG5646	InterPro IPR014922
GG619_RS05280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GG619_RS05295	COG0398	Pfam SNARE associated Golgi protein
GG619_RS05300	COG0681	Belongs to the peptidase S26 family
GG619_RS05305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GG619_RS05310	COG1846	Transcriptional regulator
GG619_RS05315	COG3180	Ammonia monooxygenase
GG619_RS05320	COG2814	Major facilitator Superfamily
GG619_RS05330	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GG619_RS05335	COG2323	membrane
GG619_RS05350	COG0420	3'-5' exonuclease activity
GG619_RS05355	COG0419	ATPase involved in DNA repair
GG619_RS05360	COG1403	HNH endonuclease
GG619_RS05400	COG0179	Fumarylacetoacetate (FAA) hydrolase
GG619_RS05420	COG0367	asparagine synthase
GG619_RS05425	COG1562	ergosterol biosynthetic process
GG619_RS05430	COG0534	Mate efflux family protein
GG619_RS05435	COG2207	Transcriptional regulator
GG619_RS05435	COG1917	Cupin 2, conserved barrel domain protein
GG619_RS05440	COG2318	DinB family
GG619_RS05445	COG1279	arginine transmembrane transporter activity
GG619_RS05450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GG619_RS05455	COG1357	PFAM Pentapeptide repeats (8 copies)
GG619_RS05460	COG2153	protein acetylation
GG619_RS05465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GG619_RS05465	COG0646	methionine synthase
GG619_RS05475	COG2996	Protein conserved in bacteria
GG619_RS05480	COG1744	ABC transporter substrate-binding protein PnrA-like
GG619_RS05485	COG0840	transmembrane signaling receptor activity
GG619_RS05490	COG2124	cytochrome p450
GG619_RS05500	COG1307	EDD domain protein, DegV family
GG619_RS05505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GG619_RS05520	COG0561	phosphatase activity
GG619_RS05525	COG1073	alpha beta
GG619_RS05530	COG2151	metal-sulfur cluster biosynthetic enzyme
GG619_RS05540	COG0277	FAD linked oxidase domain protein
GG619_RS05545	COG2271	Major facilitator Superfamily
GG619_RS05555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GG619_RS05565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GG619_RS05570	COG0505	Belongs to the CarA family
GG619_RS05575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GG619_RS05580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GG619_RS05595	COG2267	carboxylic ester hydrolase activity
GG619_RS05605	COG1744	ABC transporter substrate-binding protein PnrA-like
GG619_RS05620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GG619_RS05625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GG619_RS05630	COG5504	Zn-dependent protease
GG619_RS05635	COG0444	Belongs to the ABC transporter superfamily
GG619_RS05640	COG4608	Belongs to the ABC transporter superfamily
GG619_RS05650	COG0601	transmembrane transport
GG619_RS05655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GG619_RS05665	COG0180	Tryptophanyl-tRNA synthetase
GG619_RS05670	COG4166	transmembrane transport
GG619_RS05675	COG0601	transmembrane transport
GG619_RS05680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GG619_RS05685	COG0444	Belongs to the ABC transporter superfamily
GG619_RS05690	COG4608	Belongs to the ABC transporter superfamily
GG619_RS05700	COG0456	acetyltransferase
GG619_RS05705	COG1393	Belongs to the ArsC family
GG619_RS05710	COG0861	Integral membrane protein TerC family
GG619_RS05715	COG4862	establishment of competence for transformation
GG619_RS05720	COG4469	Competence protein
GG619_RS05725	COG1164	Oligoendopeptidase f
GG619_RS05730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GG619_RS05735	COG2346	COG2346, Truncated hemoglobins
GG619_RS05740	COG0741	lytic transglycosylase activity
GG619_RS05745	COG4116	CYTH
GG619_RS05755	COG2357	RelA SpoT domain protein
GG619_RS05760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GG619_RS05765	COG0564	pseudouridine synthase activity
GG619_RS05775	COG0569	domain protein
GG619_RS05775	COG0475	glutathione-regulated potassium exporter activity
GG619_RS05780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GG619_RS05785	COG0352	thiamine-phosphate diphosphorylase activity
GG619_RS05790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GG619_RS05795	COG2104	thiamine diphosphate biosynthetic process
GG619_RS05805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GG619_RS05810	COG0351	phosphomethylpyrimidine kinase
GG619_RS05815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GG619_RS05870	COG0210	DNA helicase
GG619_RS05890	COG1131	(ABC) transporter
GG619_RS05900	COG2153	protein acetylation
GG619_RS05910	COG2382	esterase
GG619_RS05915	COG0626	cystathionine gamma-synthase activity
GG619_RS05920	COG0626	cystathionine gamma-synthase activity
GG619_RS06000	COG5444	nuclease activity
GG619_RS06035	COG2367	Beta-lactamase
GG619_RS06040	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GG619_RS06050	COG1846	Transcriptional regulator
GG619_RS06060	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GG619_RS06065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GG619_RS06070	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GG619_RS06075	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GG619_RS06075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GG619_RS06080	COG1447	Phosphotransferase system cellobiose-specific component IIA
GG619_RS06125	COG2205	protein histidine kinase activity
GG619_RS06135	COG3383	formate dehydrogenase (NAD+) activity
GG619_RS06140	COG2427	Protein of unknown function (DUF1641)
GG619_RS06145	COG2124	cytochrome p450
GG619_RS06150	COG1819	glycosyl
GG619_RS06160	COG1587	Uroporphyrinogen-III synthase
GG619_RS06165	COG0390	transport system, permease component
GG619_RS06170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GG619_RS06175	COG0697	spore germination
GG619_RS06180	COG4297	protein containing double-stranded beta helix domain
GG619_RS06190	COG1252	NADH dehydrogenase
GG619_RS06200	COG2211	Major facilitator Superfamily
GG619_RS06205	COG1609	Transcriptional regulator
GG619_RS06210	COG0246	Mannitol dehydrogenase
GG619_RS06215	COG2721	sulfolactate sulfo-lyase activity
GG619_RS06220	COG0730	response to heat
GG619_RS06225	COG2318	DinB family
GG619_RS06230	COG0457	Tetratricopeptide repeat
GG619_RS06240	COG1388	LysM domain
GG619_RS06240	COG5632	N-Acetylmuramoyl-L-alanine amidase
GG619_RS06240	COG3409	Peptidoglycan-binding domain 1 protein
GG619_RS06250	COG4195	phage-related replication protein
GG619_RS06255	COG3546	catalase activity
GG619_RS06260	COG2856	Zn peptidase
GG619_RS06265	COG1396	sequence-specific DNA binding
GG619_RS06275	COG1522	sequence-specific DNA binding
GG619_RS06280	COG1484	DNA-dependent DNA replication
GG619_RS06295	COG1595	DNA-templated transcription, initiation
GG619_RS06300	COG3728	DNA packaging
GG619_RS06300	COG5484	DNA packaging
GG619_RS06305	COG1783	phage Terminase large subunit
GG619_RS06310	COG5518	Phage portal protein
GG619_RS06315	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GG619_RS06320	COG4653	Phage capsid family
GG619_RS06370	COG5412	phage tail tape measure protein
GG619_RS06370	COG5412	phage tail tape measure protein
GG619_RS06370	COG3953	SLT domain
GG619_RS06370	COG3953	SLT domain
GG619_RS06370	COG3953	SLT domain
GG619_RS06370	COG5412	phage tail tape measure protein
GG619_RS06375	COG1652	LysM domain
GG619_RS06380	COG4193	domain, Protein
GG619_RS06390	COG3628	GPW Gp25 family protein
GG619_RS06395	COG3299	homolog of phage Mu protein gp47
GG619_RS06400	COG3778	Protein conserved in bacteria
GG619_RS06440	COG5632	N-Acetylmuramoyl-L-alanine amidase
GG619_RS06440	COG3409	Peptidoglycan-binding domain 1 protein
GG619_RS06455	COG0306	phosphate transporter
GG619_RS06460	COG1392	Phosphate transport regulator
GG619_RS06465	COG0531	amino acid
GG619_RS06470	COG0346	lactoylglutathione lyase activity
GG619_RS06475	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GG619_RS06480	COG0463	Glycosyl transferase, family 2
GG619_RS06485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GG619_RS06490	COG0477	Major facilitator Superfamily
GG619_RS06495	COG2362	D-Aminopeptidase
GG619_RS06500	COG0601	transmembrane transport
GG619_RS06505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GG619_RS06510	COG0444	Belongs to the ABC transporter superfamily
GG619_RS06515	COG4166	transmembrane transport
GG619_RS06520	COG1619	proteins homologs of microcin C7 resistance protein MccF
GG619_RS06525	COG4948	Mandelate Racemase Muconate Lactonizing
GG619_RS06530	COG0791	NLP P60 protein
GG619_RS06535	COG4608	Belongs to the ABC transporter superfamily
GG619_RS06540	COG2706	6-phosphogluconolactonase activity
GG619_RS06545	COG1834	amidinotransferase
GG619_RS06550	COG1607	acyl-coa hydrolase
GG619_RS06555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GG619_RS06560	COG2076	Multidrug Resistance protein
GG619_RS06565	COG2076	Multidrug Resistance protein
GG619_RS06570	COG0788	formyltetrahydrofolate deformylase activity
GG619_RS06575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GG619_RS06585	COG1764	response to oxidative stress
GG619_RS06590	COG1846	Transcriptional regulator
GG619_RS06595	COG1764	response to oxidative stress
GG619_RS06610	COG0463	Glycosyl transferase, family 2
GG619_RS06610	COG0457	Tetratricopeptide repeat
GG619_RS06620	COG2814	Major facilitator Superfamily
GG619_RS06625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GG619_RS06635	COG1404	Belongs to the peptidase S8 family
GG619_RS06640	COG1366	Belongs to the anti-sigma-factor antagonist family
GG619_RS06645	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GG619_RS06650	COG1122	ATPase activity
GG619_RS06655	COG4721	ABC-type cobalt transport system, permease component
GG619_RS06660	COG3858	chitin binding
GG619_RS06660	COG1388	LysM domain
GG619_RS06675	COG2239	Acts as a magnesium transporter
GG619_RS06680	COG0789	Transcriptional regulator
GG619_RS06695	COG1846	Transcriptional regulator
GG619_RS06700	COG0726	polysaccharide deacetylase
GG619_RS06705	COG3285	dna ligase
GG619_RS06705	COG1793	dna ligase
GG619_RS06710	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GG619_RS06715	COG0586	Pfam SNARE associated Golgi protein
GG619_RS06720	COG0861	Integral membrane protein TerC family
GG619_RS06725	COG1191	sigma factor activity
GG619_RS06750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GG619_RS06755	COG2323	membrane
GG619_RS06765	COG3594	Acyltransferase
GG619_RS06770	COG5002	protein histidine kinase activity
GG619_RS06775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GG619_RS06790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GG619_RS06795	COG0436	Aminotransferase
GG619_RS06825	COG3852	Histidine kinase
GG619_RS06830	COG1846	Transcriptional regulator
GG619_RS06835	COG1360	Flagellar Motor Protein
GG619_RS06840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GG619_RS06845	COG0542	response to heat
GG619_RS06850	COG3949	Membrane
GG619_RS06865	COG0720	synthase
GG619_RS06870	COG0602	queuosine metabolic process
GG619_RS06880	COG1733	regulation of RNA biosynthetic process
GG619_RS06885	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS06905	COG4873	Protein conserved in bacteria
GG619_RS06915	COG3773	Cell wall hydrolase
GG619_RS06920	COG2244	polysaccharide biosynthetic process
GG619_RS06925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GG619_RS06930	COG2217	Heavy metal translocating P-type atpase
GG619_RS06935	COG0006	proline dipeptidase activity
GG619_RS06940	COG1609	Transcriptional regulator
GG619_RS06945	COG3711	transcriptional antiterminator
GG619_RS06950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GG619_RS06950	COG1263	PTS System
GG619_RS06950	COG2190	(PTS) system
GG619_RS06955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GG619_RS06960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GG619_RS06970	COG1533	DNA photolyase activity
GG619_RS06975	COG0840	transmembrane signaling receptor activity
GG619_RS06980	COG2084	Dehydrogenase
GG619_RS06985	COG2340	Cysteine-rich secretory protein family
GG619_RS06990	COG0768	penicillin binding
GG619_RS06995	COG4191	Histidine kinase
GG619_RS07000	COG0436	Aminotransferase
GG619_RS07005	COG0835	chemotaxis
GG619_RS07005	COG0784	Response regulator, receiver
GG619_RS07015	COG2814	Major facilitator Superfamily
GG619_RS07020	COG1376	ErfK ybiS ycfS ynhG family protein
GG619_RS07025	COG1408	metallophosphoesterase
GG619_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS07040	COG2200	EAL domain
GG619_RS07045	COG4703	Protein of unknown function (DUF1797)
GG619_RS07050	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GG619_RS07060	COG0517	IMP dehydrogenase activity
GG619_RS07065	COG0583	DNA-binding transcription factor activity
GG619_RS07070	COG0716	FMN binding
GG619_RS07080	COG0716	FMN binding
GG619_RS07100	COG0668	transmembrane transport
GG619_RS07105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GG619_RS07125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GG619_RS07130	COG0303	'Molybdopterin
GG619_RS07135	COG1763	Mo-molybdopterin cofactor biosynthetic process
GG619_RS07140	COG0314	molybdopterin synthase activity
GG619_RS07145	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GG619_RS07155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GG619_RS07160	COG1136	(ABC) transporter
GG619_RS07165	COG0577	efflux transmembrane transporter activity
GG619_RS07170	COG1349	DNA-binding transcription factor activity
GG619_RS07175	COG1105	Belongs to the carbohydrate kinase PfkB family
GG619_RS07180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GG619_RS07180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GG619_RS07180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GG619_RS07185	COG0681	Belongs to the peptidase S26 family
GG619_RS07195	COG0488	(ABC) transporter
GG619_RS07200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GG619_RS07205	COG2309	aminopeptidase activity
GG619_RS07215	COG1077	Cell shape determining protein MreB Mrl
GG619_RS07220	COG2002	toxin-antitoxin pair type II binding
GG619_RS07225	COG3852	Histidine kinase
GG619_RS07230	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GG619_RS07230	COG2105	PFAM AIG2 family protein
GG619_RS07235	COG0569	domain protein
GG619_RS07245	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GG619_RS07255	COG0561	phosphatase activity
GG619_RS07260	COG0242	peptide deformylase activity
GG619_RS07270	COG0497	DNA recombination
GG619_RS07280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS07280	COG3321	synthase
GG619_RS07280	COG4221	oxidoreductase activity
GG619_RS07285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS07285	COG0300	oxidoreductase activity
GG619_RS07285	COG3321	synthase
GG619_RS07285	COG4221	oxidoreductase activity
GG619_RS07290	COG4221	oxidoreductase activity
GG619_RS07290	COG3321	synthase
GG619_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS07290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS07295	COG4221	oxidoreductase activity
GG619_RS07295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS07295	COG3321	synthase
GG619_RS07295	COG0300	oxidoreductase activity
GG619_RS07300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS07300	COG4221	oxidoreductase activity
GG619_RS07300	COG3321	synthase
GG619_RS07300	COG0300	oxidoreductase activity
GG619_RS07305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS07305	COG0300	oxidoreductase activity
GG619_RS07305	COG3321	synthase
GG619_RS07305	COG4221	oxidoreductase activity
GG619_RS07310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS07310	COG4221	oxidoreductase activity
GG619_RS07310	COG3321	synthase
GG619_RS07310	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS07315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GG619_RS07320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GG619_RS07325	COG0022	dehydrogenase e1 component
GG619_RS07330	COG0508	dehydrogenase complex catalyzes the overall conversion of
GG619_RS07335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GG619_RS07340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GG619_RS07355	COG1982	Orn Lys Arg decarboxylase major
GG619_RS07375	COG0483	inositol monophosphate 1-phosphatase activity
GG619_RS07385	COG3227	Zinc metalloprotease (Elastase)
GG619_RS07400	COG1595	DNA-templated transcription, initiation
GG619_RS07420	COG1217	gtp-binding protein TYPA
GG619_RS07430	COG4896	Protein conserved in bacteria
GG619_RS07440	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GG619_RS07445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GG619_RS07450	COG2066	Belongs to the glutaminase family
GG619_RS07460	COG0772	Belongs to the SEDS family
GG619_RS07465	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GG619_RS07480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GG619_RS07480	COG2010	Cytochrome c
GG619_RS07485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GG619_RS07490	COG1845	cytochrome c oxidase, subunit III
GG619_RS07495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GG619_RS07500	COG3336	cytochrome c oxidase
GG619_RS07510	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GG619_RS07515	COG2340	Cysteine-rich secretory protein family
GG619_RS07530	COG3679	Belongs to the UPF0342 family
GG619_RS07540	COG0742	ribosomal rna small subunit methyltransferase
GG619_RS07550	COG3314	Sporulation integral membrane protein YlbJ
GG619_RS07555	COG1752	Esterase of the alpha-beta hydrolase superfamily
GG619_RS07560	COG3480	Lon protease (S16) C-terminal proteolytic domain
GG619_RS07570	COG1399	metal-binding, possibly nucleic acid-binding protein
GG619_RS07590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GG619_RS07610	COG4839	cell division protein FtsL
GG619_RS07615	COG0768	penicillin binding
GG619_RS07620	COG0768	penicillin binding
GG619_RS07640	COG0772	Belongs to the SEDS family
GG619_RS07655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GG619_RS07660	COG0849	cell division
GG619_RS07665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GG619_RS07670	COG1404	Belongs to the peptidase S8 family
GG619_RS07670	COG4412	M6 family metalloprotease domain protein
GG619_RS07680	COG1191	sigma factor activity
GG619_RS07685	COG1191	sigma factor activity
GG619_RS07690	COG1119	ATPase activity
GG619_RS07695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GG619_RS07700	COG1873	PFAM PRC-barrel domain
GG619_RS07705	COG1496	oxidoreductase activity
GG619_RS07710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GG619_RS07720	COG0762	integral membrane protein
GG619_RS07725	COG2302	S4 RNA-binding domain
GG619_RS07730	COG3599	regulation of cell shape
GG619_RS07735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GG619_RS07740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GG619_RS07750	COG0564	pseudouridine synthase activity
GG619_RS07760	COG2233	PERMEase
GG619_RS07770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GG619_RS07775	COG0505	Belongs to the CarA family
GG619_RS07780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GG619_RS07795	COG0284	orotidine-5'-phosphate decarboxylase activity
GG619_RS07800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GG619_RS07810	COG0306	phosphate transporter
GG619_RS07825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GG619_RS07830	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GG619_RS07835	COG1648	precorrin-2 dehydrogenase activity
GG619_RS07845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GG619_RS07850	COG1561	YicC-like family, N-terminal region
GG619_RS07860	COG0194	GDP metabolic process
GG619_RS07870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GG619_RS07875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GG619_RS07880	COG0242	peptide deformylase activity
GG619_RS07890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GG619_RS07890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GG619_RS07900	COG0631	protein serine/threonine phosphatase activity
GG619_RS07905	COG0515	serine threonine protein kinase
GG619_RS07905	COG2815	serine threonine protein kinase
GG619_RS07915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GG619_RS07920	COG1564	THIamine pyrophosphokinase
GG619_RS07935	COG1302	Protein conserved in bacteria
GG619_RS07940	COG1461	Dihydroxyacetone kinase
GG619_RS07945	COG1760	l-serine dehydratase
GG619_RS07950	COG1760	l-serine dehydratase
GG619_RS07955	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GG619_RS07970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GG619_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS07990	COG1196	nuclear chromosome segregation
GG619_RS07995	COG0552	protein localization to endoplasmic reticulum
GG619_RS08010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GG619_RS08020	COG1837	Belongs to the UPF0109 family
GG619_RS08045	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GG619_RS08060	COG2257	FlhB HrpN YscU SpaS Family
GG619_RS08070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GG619_RS08075	COG0758	DNA mediated transformation
GG619_RS08080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GG619_RS08090	COG4974	Belongs to the 'phage' integrase family
GG619_RS08110	COG1815	bacterial-type flagellum-dependent cell motility
GG619_RS08115	COG1558	bacterial-type flagellum-dependent cell motility
GG619_RS08120	COG1677	Flagellar hook-basal body complex protein FliE
GG619_RS08125	COG1766	The M ring may be actively involved in energy transduction
GG619_RS08130	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GG619_RS08135	COG1317	bacterial-type flagellum organization
GG619_RS08140	COG1157	protein secretion by the type III secretion system
GG619_RS08145	COG2882	bacterial-type flagellum organization
GG619_RS08150	COG3334	PFAM MgtE intracellular
GG619_RS08155	COG3144	bacterial-type flagellum assembly
GG619_RS08160	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GG619_RS08165	COG4786	Flagellar basal body rod
GG619_RS08170	COG1582	Flagellar protein (FlbD)
GG619_RS08175	COG1580	Controls the rotational direction of flagella during chemotaxis
GG619_RS08180	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GG619_RS08185	COG1776	CheC inhibitor of MCP methylation
GG619_RS08185	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GG619_RS08190	COG2201	protein-glutamate methylesterase activity
GG619_RS08195	COG3190	flagellar
GG619_RS08200	COG1338	Plays a role in the flagellum-specific transport system
GG619_RS08205	COG1987	bacterial-type flagellum assembly
GG619_RS08210	COG1684	flagellar biosynthetic protein fliR
GG619_RS08215	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GG619_RS08220	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GG619_RS08225	COG1419	protein localization to endoplasmic reticulum
GG619_RS08230	COG0455	bacterial-type flagellum organization
GG619_RS08235	COG2201	protein-glutamate methylesterase activity
GG619_RS08240	COG0643	Histidine kinase
GG619_RS08240	COG2198	Histidine kinase
GG619_RS08245	COG0835	chemotaxis
GG619_RS08250	COG1776	CheC inhibitor of MCP methylation
GG619_RS08260	COG1191	sigma factor activity
GG619_RS08290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GG619_RS08295	COG4589	Belongs to the CDS family
GG619_RS08305	COG0750	zinc metalloprotease
GG619_RS08315	COG2176	DNA-directed DNA polymerase activity
GG619_RS08325	COG0195	Participates in both transcription termination and antitermination
GG619_RS08330	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GG619_RS08335	COG1358	cellular component organization or biogenesis
GG619_RS08345	COG1550	Protein conserved in bacteria
GG619_RS08360	COG0196	riboflavin kinase activity
GG619_RS08375	COG0726	polysaccharide deacetylase
GG619_RS08380	COG0612	Peptidase, M16
GG619_RS08385	COG1873	PFAM PRC-barrel domain
GG619_RS08390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GG619_RS08395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GG619_RS08400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GG619_RS08405	COG0527	aspartate kinase activity
GG619_RS08415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GG619_RS08420	COG0740	serine-type endopeptidase activity
GG619_RS08430	COG1674	ftsk spoiiie
GG619_RS08430	COG4980	gas vesicle protein
GG619_RS08435	COG2188	Transcriptional regulator
GG619_RS08440	COG2814	Major facilitator Superfamily
GG619_RS08445	COG1846	Transcriptional regulator
GG619_RS08450	COG2409	Drug exporters of the RND superfamily
GG619_RS08450	COG1033	growth of symbiont in host cell
GG619_RS08455	COG0612	Peptidase, M16
GG619_RS08460	COG0612	Peptidase, M16
GG619_RS08465	COG0300	oxidoreductase activity
GG619_RS08480	COG1426	Protein conserved in bacteria
GG619_RS08485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GG619_RS08500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GG619_RS08510	COG1692	metallophosphoesterase
GG619_RS08515	COG2359	stage V sporulation protein S
GG619_RS08535	COG4550	Control of competence regulator ComK, YlbF/YmcA
GG619_RS08555	COG0582	viral genome integration into host DNA
GG619_RS08595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS08600	COG3425	synthase
GG619_RS08605	COG1024	Enoyl-CoA hydratase
GG619_RS08610	COG1024	Enoyl-CoA hydratase
GG619_RS08615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS08615	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS08615	COG0300	oxidoreductase activity
GG619_RS08615	COG3321	synthase
GG619_RS08615	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS08620	COG4221	oxidoreductase activity
GG619_RS08620	COG0300	oxidoreductase activity
GG619_RS08620	COG3321	synthase
GG619_RS08620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS08625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS08625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GG619_RS08625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS08625	COG3321	synthase
GG619_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS08625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS08625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GG619_RS08625	COG3321	synthase
GG619_RS08625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS08630	COG4221	oxidoreductase activity
GG619_RS08630	COG3321	synthase
GG619_RS08630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS08635	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GG619_RS08635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS08635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GG619_RS08635	COG3321	synthase
GG619_RS08640	COG2124	cytochrome p450
GG619_RS08645	COG3209	COG3209 Rhs family protein
GG619_RS08650	COG3619	membrane
GG619_RS08660	COG1404	Belongs to the peptidase S8 family
GG619_RS08670	COG4195	phage-related replication protein
GG619_RS08675	COG1764	response to oxidative stress
GG619_RS08685	COG2076	Multidrug Resistance protein
GG619_RS08725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GG619_RS08730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GG619_RS08735	COG4112	unkown
GG619_RS08740	COG0860	N-Acetylmuramoyl-L-alanine amidase
GG619_RS08750	COG0464	growth
GG619_RS08755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GG619_RS08760	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GG619_RS08765	COG0789	Transcriptional regulator
GG619_RS08770	COG0174	glutamine synthetase
GG619_RS08795	COG2211	Major facilitator Superfamily
GG619_RS08800	COG3507	Belongs to the glycosyl hydrolase 43 family
GG619_RS08815	COG1070	Carbohydrate kinase
GG619_RS08820	COG0574	Belongs to the PEP-utilizing enzyme family
GG619_RS08820	COG3848	Pyruvate phosphate dikinase
GG619_RS08840	COG1064	alcohol dehydrogenase
GG619_RS08850	COG0456	acetyltransferase
GG619_RS08875	COG3397	chitin binding
GG619_RS08885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GG619_RS08895	COG5434	Belongs to the glycosyl hydrolase 28 family
GG619_RS08900	COG0756	dUTP diphosphatase activity
GG619_RS08910	COG4195	phage-related replication protein
GG619_RS08940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GG619_RS08950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GG619_RS08970	COG0785	Cytochrome C biogenesis protein
GG619_RS08975	COG2201	protein-glutamate methylesterase activity
GG619_RS08980	COG4846	Membrane protein involved in cytochrome C biogenesis
GG619_RS08990	COG0071	Belongs to the small heat shock protein (HSP20) family
GG619_RS09005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GG619_RS09010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GG619_RS09030	COG0824	Thioesterase
GG619_RS09040	COG4841	protein insertion into membrane
GG619_RS09050	COG1832	CoA-binding protein
GG619_RS09055	COG0187	DNA topoisomerase II activity
GG619_RS09060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GG619_RS09070	COG1115	amino acid carrier protein
GG619_RS09080	COG1063	alcohol dehydrogenase
GG619_RS09085	COG0800	Aldolase
GG619_RS09090	COG1312	Catalyzes the dehydration of D-mannonate
GG619_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS09100	COG1609	Transcriptional regulator
GG619_RS09105	COG2271	Major facilitator Superfamily
GG619_RS09145	COG0457	Tetratricopeptide repeat
GG619_RS09170	COG1136	(ABC) transporter
GG619_RS09170	COG0577	efflux transmembrane transporter activity
GG619_RS09200	COG2205	protein histidine kinase activity
GG619_RS09205	COG0745	RESPONSE REGULATOR receiver
GG619_RS09215	COG3507	Belongs to the glycosyl hydrolase 43 family
GG619_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS09245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GG619_RS09250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GG619_RS09255	COG2610	gluconate transmembrane transporter activity
GG619_RS09260	COG2124	cytochrome p450
GG619_RS09280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GG619_RS09290	COG2246	polysaccharide biosynthetic process
GG619_RS09295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GG619_RS09300	COG0586	Pfam SNARE associated Golgi protein
GG619_RS09305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GG619_RS09310	COG1024	Enoyl-CoA hydratase
GG619_RS09315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GG619_RS09320	COG0511	ligase activity, forming carbon-carbon bonds
GG619_RS09325	COG0439	Biotin carboxylase
GG619_RS09330	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS09335	COG1960	acyl-CoA dehydrogenase activity
GG619_RS09340	COG1649	PFAM Uncharacterised BCR, COG1649
GG619_RS09350	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GG619_RS09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS09355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS09360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS09365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS09370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS09375	COG2027	D-alanyl-D-alanine carboxypeptidase
GG619_RS09380	COG2017	converts alpha-aldose to the beta-anomer
GG619_RS09385	COG0534	Mate efflux family protein
GG619_RS09400	COG0582	viral genome integration into host DNA
GG619_RS09405	COG0166	Belongs to the GPI family
GG619_RS09410	COG0405	Gamma-glutamyltransferase
GG619_RS09415	COG2814	Major facilitator Superfamily
GG619_RS09420	COG0640	Transcriptional regulator
GG619_RS09425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GG619_RS09435	COG0604	alcohol dehydrogenase
GG619_RS09440	COG0493	'glutamate synthase
GG619_RS09445	COG0067	glutamate synthase
GG619_RS09445	COG0069	glutamate synthase activity
GG619_RS09445	COG0070	glutamate synthase
GG619_RS09450	COG0583	DNA-binding transcription factor activity
GG619_RS09455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GG619_RS09470	COG0300	oxidoreductase activity
GG619_RS09475	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GG619_RS09485	COG2814	Major facilitator Superfamily
GG619_RS09490	COG1070	Carbohydrate kinase
GG619_RS09495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GG619_RS09500	COG0243	molybdopterin cofactor binding
GG619_RS09530	COG5444	nuclease activity
GG619_RS09535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GG619_RS09545	COG1309	transcriptional regulator
GG619_RS09550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GG619_RS09560	COG0640	Transcriptional regulator
GG619_RS09565	COG0741	lytic transglycosylase activity
GG619_RS09570	COG2322	membrane
GG619_RS09585	COG1619	proteins homologs of microcin C7 resistance protein MccF
GG619_RS09595	COG1388	LysM domain
GG619_RS09595	COG3584	3D domain protein
GG619_RS09600	COG0514	ATP-dependent DNA helicase (RecQ)
GG619_RS09610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GG619_RS09615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GG619_RS09630	COG0071	Belongs to the small heat shock protein (HSP20) family
GG619_RS09660	COG1012	belongs to the aldehyde dehydrogenase family
GG619_RS09665	COG1657	PFAM Prenyltransferase squalene oxidase
GG619_RS09670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GG619_RS09675	COG0733	neurotransmitter:sodium symporter activity
GG619_RS09680	COG0385	Bile acid
GG619_RS09685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GG619_RS09690	COG0508	dehydrogenase complex catalyzes the overall conversion of
GG619_RS09700	COG4548	von Willebrand factor, type A
GG619_RS09705	COG0714	Associated with various cellular activities
GG619_RS09710	COG2032	superoxide dismutase activity
GG619_RS09715	COG1388	LysM domain
GG619_RS09715	COG0791	NLP P60 protein
GG619_RS09720	COG1819	glycosyl
GG619_RS09725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GG619_RS09730	COG0534	Mate efflux family protein
GG619_RS09735	COG1366	Belongs to the anti-sigma-factor antagonist family
GG619_RS09740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GG619_RS09745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GG619_RS09755	COG2962	Rard protein
GG619_RS09770	COG1942	4-Oxalocrotonate Tautomerase
GG619_RS09780	COG1733	regulation of RNA biosynthetic process
GG619_RS09785	COG0778	Nitroreductase
GG619_RS09790	COG0400	carboxylic ester hydrolase activity
GG619_RS09795	COG0346	lactoylglutathione lyase activity
GG619_RS09805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GG619_RS09815	COG2723	6-phospho-beta-galactosidase activity
GG619_RS09820	COG2188	Transcriptional regulator
GG619_RS09825	COG0793	Belongs to the peptidase S41A family
GG619_RS09825	COG3409	Peptidoglycan-binding domain 1 protein
GG619_RS09830	COG2226	methyltransferase
GG619_RS09840	COG1876	peptidase activity
GG619_RS09860	COG0671	phosphoesterase, PA-phosphatase related
GG619_RS09885	COG1509	lysine 2,3-aminomutase activity
GG619_RS09890	COG0456	acetyltransferase
GG619_RS09895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GG619_RS09900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GG619_RS09905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GG619_RS09910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GG619_RS09915	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GG619_RS09925	COG0456	acetyltransferase
GG619_RS09930	COG0463	Glycosyl transferase, family 2
GG619_RS09945	COG4641	Protein conserved in bacteria
GG619_RS09955	COG1086	Polysaccharide biosynthesis protein
GG619_RS10005	COG1388	LysM domain
GG619_RS10010	COG0457	Tetratricopeptide repeat
GG619_RS10035	COG5444	nuclease activity
GG619_RS10040	COG4282	regulation of fungal-type cell wall biogenesis
GG619_RS10045	COG1525	nuclease
GG619_RS10050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GG619_RS10070	COG1846	Transcriptional regulator
GG619_RS10075	COG4698	Protein conserved in bacteria
GG619_RS10080	COG2755	lipolytic protein G-D-S-L family
GG619_RS10085	COG1999	signal sequence binding
GG619_RS10095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GG619_RS10100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GG619_RS10105	COG1272	protein, Hemolysin III
GG619_RS10110	COG0204	Acyl-transferase
GG619_RS10115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GG619_RS10130	COG2521	methyltransferase
GG619_RS10130	COG2136	Putative SAM-dependent methyltransferase
GG619_RS10145	COG1413	lyase activity
GG619_RS10150	COG1418	mRNA catabolic process
GG619_RS10155	COG0386	Belongs to the glutathione peroxidase family
GG619_RS10165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GG619_RS10175	COG1278	Cold shock
GG619_RS10195	COG0328	RNA-DNA hybrid ribonuclease activity
GG619_RS10200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GG619_RS10205	COG0328	RNA-DNA hybrid ribonuclease activity
GG619_RS10215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GG619_RS10230	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GG619_RS10240	COG1755	Isoprenylcysteine carboxyl methyltransferase
GG619_RS10245	COG3424	synthase
GG619_RS10270	COG1335	isochorismatase
GG619_RS10295	COG5632	N-Acetylmuramoyl-L-alanine amidase
GG619_RS10300	COG4824	toxin secretion phage lysis holin
GG619_RS10320	COG5434	Belongs to the glycosyl hydrolase 28 family
GG619_RS10325	COG1705	Flagellar rod assembly protein muramidase FlgJ
GG619_RS10335	COG5280	Phage tail tape measure protein TP901
GG619_RS10335	COG3953	SLT domain
GG619_RS10435	COG1595	DNA-templated transcription, initiation
GG619_RS10460	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GG619_RS10465	COG1484	DNA-dependent DNA replication
GG619_RS10470	COG3935	DnaD domain protein
GG619_RS10505	COG3645	SOS response
GG619_RS10505	COG3646	Phage regulatory protein
GG619_RS10520	COG3620	sequence-specific DNA binding
GG619_RS10525	COG0582	viral genome integration into host DNA
GG619_RS10530	COG2233	PERMEase
GG619_RS10540	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GG619_RS10545	COG1199	ATP-dependent helicase activity
GG619_RS10560	COG0116	Belongs to the methyltransferase superfamily
GG619_RS10590	COG3359	exonuclease
GG619_RS10595	COG1205	dead DEAH box helicase
GG619_RS10595	COG1111	helicase
GG619_RS10600	COG2190	(PTS) system
GG619_RS10605	COG0071	Belongs to the small heat shock protein (HSP20) family
GG619_RS10645	COG4499	WXG100 protein secretion system (Wss), protein YukC
GG619_RS10645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GG619_RS10655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GG619_RS10660	COG3935	DnaD domain protein
GG619_RS10670	COG0436	Aminotransferase
GG619_RS10675	COG5353	protein conserved in bacteria
GG619_RS10685	COG1199	ATP-dependent helicase activity
GG619_RS10685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GG619_RS10715	COG0438	transferase activity, transferring glycosyl groups
GG619_RS10720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GG619_RS10735	COG1694	Mazg nucleotide pyrophosphohydrolase
GG619_RS10740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GG619_RS10745	COG2140	Oxalate decarboxylase
GG619_RS10755	COG4347	Protein of unknown function (DUF1405)
GG619_RS10760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GG619_RS10760	COG2010	Cytochrome c
GG619_RS10765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GG619_RS10770	COG0723	plastoquinol--plastocyanin reductase activity
GG619_RS10785	COG0457	Tetratricopeptide repeat
GG619_RS10795	COG0287	Prephenate dehydrogenase
GG619_RS10830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GG619_RS10835	COG4401	Chorismate mutase type I
GG619_RS10850	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GG619_RS10855	COG0105	UTP biosynthetic process
GG619_RS10860	COG0142	geranyltranstransferase activity
GG619_RS10870	COG0142	geranyltranstransferase activity
GG619_RS10885	COG0776	regulation of translation
GG619_RS10890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GG619_RS10930	COG0539	negative regulation of cytoplasmic translation
GG619_RS10940	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GG619_RS10945	COG2959	enzyme of heme biosynthesis
GG619_RS10950	COG3409	Peptidoglycan-binding domain 1 protein
GG619_RS10950	COG3773	Cell wall hydrolase
GG619_RS10955	COG2339	peptidase activity
GG619_RS10960	COG0492	ferredoxin-NADP+ reductase activity
GG619_RS10965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GG619_RS10970	COG4862	establishment of competence for transformation
GG619_RS10975	COG1408	metallophosphoesterase
GG619_RS10985	COG1388	LysM domain
GG619_RS10990	COG1266	CAAX protease self-immunity
GG619_RS10995	COG0514	ATP-dependent DNA helicase (RecQ)
GG619_RS11000	COG4955	Helix-turn-helix domain
GG619_RS11005	COG1141	Ferredoxin
GG619_RS11010	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GG619_RS11015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GG619_RS11025	COG1595	DNA-templated transcription, initiation
GG619_RS11030	COG5002	protein histidine kinase activity
GG619_RS11035	COG0745	RESPONSE REGULATOR receiver
GG619_RS11040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GG619_RS11045	COG1333	cytochrome c biogenesis protein
GG619_RS11050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GG619_RS11055	COG1187	pseudouridine synthase activity
GG619_RS11060	COG0700	Nucleoside recognition
GG619_RS11065	COG2715	membrane protein required for spore maturation
GG619_RS11070	COG1686	Belongs to the peptidase S11 family
GG619_RS11095	COG1547	Domain of unknown function (DUF309)
GG619_RS11100	COG0456	acetyltransferase
GG619_RS11115	COG0307	riboflavin synthase, alpha
GG619_RS11120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GG619_RS11120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GG619_RS11130	COG0681	Belongs to the peptidase S26 family
GG619_RS11140	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GG619_RS11145	COG4086	secreted protein
GG619_RS11150	COG0019	diaminopimelate decarboxylase activity
GG619_RS11155	COG0697	spore germination
GG619_RS11170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GG619_RS11190	COG1191	sigma factor activity
GG619_RS11200	COG1366	Belongs to the anti-sigma-factor antagonist family
GG619_RS11205	COG1686	Belongs to the peptidase S11 family
GG619_RS11210	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GG619_RS11215	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GG619_RS11220	COG4974	Belongs to the 'phage' integrase family
GG619_RS11230	COG0735	belongs to the Fur family
GG619_RS11235	COG1300	Membrane
GG619_RS11250	COG0281	malic enzyme
GG619_RS11255	COG1757	Na H antiporter
GG619_RS11260	COG1027	Aspartate ammonia-lyase
GG619_RS11265	COG0252	asparaginase activity
GG619_RS11270	COG1396	sequence-specific DNA binding
GG619_RS11275	COG1379	DNA repair
GG619_RS11280	COG0494	nUDIX hydrolase
GG619_RS11290	COG0667	Aldo Keto reductase
GG619_RS11300	COG1073	alpha beta
GG619_RS11310	COG4918	Iron-sulphur cluster biosynthesis
GG619_RS11315	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GG619_RS11315	COG0456	acetyltransferase
GG619_RS11320	COG2329	Antibiotic biosynthesis monooxygenase
GG619_RS11325	COG0456	acetyltransferase
GG619_RS11330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GG619_RS11345	COG0628	permease
GG619_RS11355	COG0346	lactoylglutathione lyase activity
GG619_RS11365	COG3048	D-serine ammonia-lyase activity
GG619_RS11370	COG0300	oxidoreductase activity
GG619_RS11375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GG619_RS11380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GG619_RS11385	COG1024	Enoyl-CoA hydratase
GG619_RS11390	COG3425	synthase
GG619_RS11400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS11400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GG619_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS11400	COG3321	synthase
GG619_RS11400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS11405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS11405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS11405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GG619_RS11405	COG3321	synthase
GG619_RS11410	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS11410	COG0300	oxidoreductase activity
GG619_RS11410	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS11410	COG3321	synthase
GG619_RS11410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS11415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS11415	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS11415	COG3321	synthase
GG619_RS11415	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS11415	COG0300	oxidoreductase activity
GG619_RS11420	COG3321	synthase
GG619_RS11420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS11420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GG619_RS11420	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS11420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS11425	COG3321	synthase
GG619_RS11425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS11425	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS11425	COG0300	oxidoreductase activity
GG619_RS11430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GG619_RS11430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GG619_RS11430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS11430	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS11430	COG3321	synthase
GG619_RS11435	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS11440	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS11455	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GG619_RS11455	COG2070	2-Nitropropane dioxygenase
GG619_RS11460	COG0250	Participates in transcription elongation, termination and antitermination
GG619_RS11475	COG0596	Alpha beta hydrolase
GG619_RS11490	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GG619_RS11495	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GG619_RS11510	COG0706	membrane insertase activity
GG619_RS11515	COG2195	Cleaves the N-terminal amino acid of tripeptides
GG619_RS11520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GG619_RS11525	COG0346	lactoylglutathione lyase activity
GG619_RS11535	COG1376	ErfK ybiS ycfS ynhG family protein
GG619_RS11540	COG4129	membrane
GG619_RS11545	COG1126	abc transporter atp-binding protein
GG619_RS11550	COG0765	amino acid transport
GG619_RS11555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GG619_RS11565	COG1597	lipid kinase activity
GG619_RS11570	COG0508	dehydrogenase complex catalyzes the overall conversion of
GG619_RS11575	COG0022	dehydrogenase e1 component
GG619_RS11580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GG619_RS11585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GG619_RS11590	COG3426	butyrate kinase activity
GG619_RS11595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GG619_RS11600	COG0280	phosphate acetyltransferase
GG619_RS11605	COG3290	protein histidine kinase activity
GG619_RS11605	COG3829	transcription factor binding
GG619_RS11615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GG619_RS11620	COG2079	MmgE PrpD family protein
GG619_RS11625	COG0372	Belongs to the citrate synthase family
GG619_RS11630	COG1960	acyl-CoA dehydrogenase activity
GG619_RS11635	COG1250	3-hydroxyacyl-CoA dehydrogenase
GG619_RS11640	COG0183	Belongs to the thiolase family
GG619_RS11645	COG0584	glycerophosphoryl diester phosphodiesterase
GG619_RS11650	COG0860	N-Acetylmuramoyl-L-alanine amidase
GG619_RS11670	COG1902	pentaerythritol trinitrate reductase activity
GG619_RS11685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GG619_RS11690	COG0745	RESPONSE REGULATOR receiver
GG619_RS11695	COG0750	zinc metalloprotease
GG619_RS11700	COG0497	DNA recombination
GG619_RS11710	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GG619_RS11720	COG0142	geranyltranstransferase activity
GG619_RS11730	COG1570	exodeoxyribonuclease VII activity
GG619_RS11745	COG1302	Protein conserved in bacteria
GG619_RS11750	COG0439	Biotin carboxylase
GG619_RS11755	COG0511	ligase activity, forming carbon-carbon bonds
GG619_RS11795	COG3854	ATPases associated with a variety of cellular activities
GG619_RS11810	COG0006	proline dipeptidase activity
GG619_RS11820	COG3872	metal-dependent enzyme
GG619_RS11830	COG1752	Esterase of the alpha-beta hydrolase superfamily
GG619_RS11845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GG619_RS11865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GG619_RS11880	COG1396	sequence-specific DNA binding
GG619_RS11890	COG0681	Belongs to the peptidase S26 family
GG619_RS11915	COG4940	Competence protein ComGF
GG619_RS11925	COG4970	Tfp pilus assembly protein FimT
GG619_RS11930	COG4537	Required for transformation and DNA binding
GG619_RS11935	COG1459	type II secretion system
GG619_RS11940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GG619_RS11945	COG0598	Magnesium transport protein CorA
GG619_RS11950	COG1253	flavin adenine dinucleotide binding
GG619_RS11955	COG1366	Belongs to the anti-sigma-factor antagonist family
GG619_RS11965	COG1393	Belongs to the ArsC family
GG619_RS11975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GG619_RS11985	COG0011	TIGRFAM Protein of
GG619_RS11995	COG2866	Carboxypeptidase
GG619_RS12000	COG1940	carbohydrate kinase activity
GG619_RS12005	COG4483	Protein conserved in bacteria
GG619_RS12010	COG1757	Na H antiporter
GG619_RS12020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GG619_RS12035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GG619_RS12040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GG619_RS12045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GG619_RS12050	COG0581	inorganic phosphate transmembrane transporter activity
GG619_RS12055	COG0573	inorganic phosphate transmembrane transporter activity
GG619_RS12060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GG619_RS12070	COG0768	penicillin binding
GG619_RS12075	COG0477	Major facilitator Superfamily
GG619_RS12080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GG619_RS12085	COG2839	Protein conserved in bacteria
GG619_RS12090	COG5521	maltodextrose utilization protein MalA
GG619_RS12095	COG1388	LysM domain
GG619_RS12105	COG4709	membrane
GG619_RS12110	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GG619_RS12115	COG0735	belongs to the Fur family
GG619_RS12120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GG619_RS12135	COG0513	Belongs to the DEAD box helicase family
GG619_RS12150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GG619_RS12155	COG2384	SAM-dependent methyltransferase
GG619_RS12160	COG2010	Cytochrome c
GG619_RS12165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GG619_RS12170	COG0358	DNA primase activity
GG619_RS12185	COG0517	IMP dehydrogenase activity
GG619_RS12190	COG0751	glycine-tRNA ligase activity
GG619_RS12210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GG619_RS12215	COG0295	cytidine deaminase activity
GG619_RS12220	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GG619_RS12230	COG1480	7TM receptor with intracellular HD hydrolase
GG619_RS12235	COG1702	phosphate starvation-inducible protein PhoH
GG619_RS12240	COG0561	phosphatase activity
GG619_RS12255	COG4864	UPF0365 protein
GG619_RS12260	COG1030	water channel activity
GG619_RS12265	COG1610	YqeY-like protein
GG619_RS12275	COG1283	sodium-dependent phosphate transmembrane transporter activity
GG619_RS12280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GG619_RS12285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GG619_RS12315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GG619_RS12330	COG0860	N-Acetylmuramoyl-L-alanine amidase
GG619_RS12345	COG1466	dna polymerase III delta subunit
GG619_RS12360	COG2333	competence protein COMEC
GG619_RS12360	COG0658	competence protein
GG619_RS12365	COG2131	deaminase
GG619_RS12370	COG1555	photosystem II stabilization
GG619_RS12370	COG1596	polysaccharide export
GG619_RS12375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GG619_RS12380	COG2226	methyltransferase
GG619_RS12385	COG0799	negative regulation of ribosome biogenesis
GG619_RS12390	COG1713	HD superfamily hydrolase involved in NAD metabolism
GG619_RS12400	COG1534	Rna-binding protein
GG619_RS12405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GG619_RS12410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GG619_RS12415	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GG619_RS12425	COG2755	lipolytic protein G-D-S-L family
GG619_RS12435	COG0398	Pfam SNARE associated Golgi protein
GG619_RS12460	COG1794	racemase activity, acting on amino acids and derivatives
GG619_RS12470	COG0114	fumarate hydratase activity
GG619_RS12475	COG0656	L-ascorbic acid biosynthetic process
GG619_RS12505	COG5002	protein histidine kinase activity
GG619_RS12505	COG0642	Histidine kinase
GG619_RS12510	COG0745	RESPONSE REGULATOR receiver
GG619_RS12515	COG2311	Membrane
GG619_RS12525	COG0454	-acetyltransferase
GG619_RS12530	COG0563	adenylate kinase activity
GG619_RS12540	COG2814	Major facilitator Superfamily
GG619_RS12550	COG0456	acetyltransferase
GG619_RS12555	COG2318	DinB family
GG619_RS12565	COG0561	phosphatase activity
GG619_RS12570	COG0561	phosphatase activity
GG619_RS12580	COG1482	cell wall glycoprotein biosynthetic process
GG619_RS12585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GG619_RS12585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GG619_RS12585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GG619_RS12600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GG619_RS12605	COG0583	DNA-binding transcription factor activity
GG619_RS12610	COG2814	Major facilitator Superfamily
GG619_RS12615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GG619_RS12615	COG2124	cytochrome p450
GG619_RS12620	COG1309	transcriptional regulator
GG619_RS12625	COG2226	methyltransferase
GG619_RS12635	COG2116	formate transmembrane transporter activity
GG619_RS12640	COG5609	conserved protein (DUF2294)
GG619_RS12645	COG3383	formate dehydrogenase (NAD+) activity
GG619_RS12650	COG2427	Protein of unknown function (DUF1641)
GG619_RS12660	COG0626	cystathionine gamma-synthase activity
GG619_RS12665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GG619_RS12690	COG0768	penicillin binding
GG619_RS12705	COG0826	peptidase U32
GG619_RS12710	COG0826	peptidase U32
GG619_RS12715	COG4122	O-methyltransferase activity
GG619_RS12720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GG619_RS12735	COG4472	Bacterial protein of unknown function (DUF965)
GG619_RS12745	COG0628	permease
GG619_RS12750	COG1126	abc transporter atp-binding protein
GG619_RS12755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GG619_RS12760	COG0765	amino acid transport
GG619_RS12765	COG0765	amino acid transport
GG619_RS12780	COG3881	PFAM PRC-barrel domain
GG619_RS12785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GG619_RS12790	COG0457	Tetratricopeptide repeat
GG619_RS12800	COG1104	cysteine desulfurase activity
GG619_RS12805	COG1959	2 iron, 2 sulfur cluster binding
GG619_RS12810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GG619_RS12815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GG619_RS12835	COG0860	N-Acetylmuramoyl-L-alanine amidase
GG619_RS12835	COG3103	Sh3 type 3 domain protein
GG619_RS12835	COG4991	sh3 domain protein
GG619_RS12845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GG619_RS12855	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GG619_RS12855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GG619_RS12860	COG5416	Lipopolysaccharide assembly protein A domain
GG619_RS12865	COG0490	domain, Protein
GG619_RS12870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GG619_RS12870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GG619_RS12880	COG2244	polysaccharide biosynthetic process
GG619_RS12885	COG2323	membrane
GG619_RS12895	COG1862	Preprotein translocase
GG619_RS12940	COG1388	LysM domain
GG619_RS12950	COG0157	Belongs to the NadC ModD family
GG619_RS12955	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GG619_RS12960	COG1104	cysteine desulfurase activity
GG619_RS12965	COG1827	regulation of RNA biosynthetic process
GG619_RS12970	COG0077	Prephenate dehydratase
GG619_RS12985	COG3290	protein histidine kinase activity
GG619_RS12990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GG619_RS12995	COG2868	ribosomal protein
GG619_RS13005	COG1994	Peptidase M50
GG619_RS13010	COG0739	heme binding
GG619_RS13015	COG2894	cell division
GG619_RS13025	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GG619_RS13035	COG1077	Cell shape determining protein MreB Mrl
GG619_RS13055	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GG619_RS13060	COG0285	dihydrofolate synthase activity
GG619_RS13065	COG0525	valine-tRNA ligase activity
GG619_RS13075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GG619_RS13080	COG1388	LysM domain
GG619_RS13090	COG0113	porphobilinogen synthase activity
GG619_RS13095	COG1587	Uroporphyrinogen-III synthase
GG619_RS13105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GG619_RS13125	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GG619_RS13130	COG0470	DNA polymerase III
GG619_RS13130	COG1067	ATP-dependent peptidase activity
GG619_RS13145	COG0457	Tetratricopeptide repeat
GG619_RS13145	COG1477	protein flavinylation
GG619_RS13160	COG0473	3-isopropylmalate dehydrogenase activity
GG619_RS13175	COG0440	acetolactate synthase activity
GG619_RS13180	COG0028	Belongs to the TPP enzyme family
GG619_RS13215	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GG619_RS13230	COG0622	Phosphoesterase
GG619_RS13235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GG619_RS13245	COG5401	PFAM Sporulation and spore germination
GG619_RS13255	COG1846	Transcriptional regulator
GG619_RS13260	COG2197	response regulator
GG619_RS13265	COG0824	Thioesterase
GG619_RS13270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GG619_RS13275	COG1053	succinate dehydrogenase
GG619_RS13280	COG2009	succinate dehydrogenase
GG619_RS13285	COG1719	4-vinyl reductase, 4VR
GG619_RS13290	COG0527	aspartate kinase activity
GG619_RS13300	COG3118	belongs to the thioredoxin family
GG619_RS13305	COG3534	alpha-L-arabinofuranosidase
GG619_RS13310	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GG619_RS13315	COG2086	electron transfer activity
GG619_RS13320	COG1024	Enoyl-CoA hydratase
GG619_RS13325	COG1309	transcriptional regulator
GG619_RS13330	COG0318	PFAM AMP-dependent synthetase and ligase
GG619_RS13340	COG3766	membrane
GG619_RS13350	COG1796	DNA polymerase
GG619_RS13350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GG619_RS13355	COG1286	toxin biosynthetic process
GG619_RS13370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GG619_RS13370	COG0072	phenylalanine-tRNA ligase activity
GG619_RS13375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GG619_RS13380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GG619_RS13390	COG3835	regulator
GG619_RS13395	COG0277	FAD linked oxidase domain protein
GG619_RS13400	COG0247	lactate metabolic process
GG619_RS13405	COG1966	Carbon starvation protein
GG619_RS13410	COG3534	alpha-L-arabinofuranosidase
GG619_RS13415	COG0395	ABC-type sugar transport system, permease component
GG619_RS13420	COG1175	transmembrane transport
GG619_RS13425	COG1653	transport
GG619_RS13435	COG0647	UMP catabolic process
GG619_RS13440	COG0235	Class ii aldolase
GG619_RS13445	COG1069	ribulokinase activity
GG619_RS13450	COG2160	L-arabinose isomerase activity
GG619_RS13455	COG3507	Belongs to the glycosyl hydrolase 43 family
GG619_RS13460	COG1363	Peptidase, m42
GG619_RS13470	COG3326	Membrane
GG619_RS13475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GG619_RS13485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GG619_RS13490	COG1346	cytolysis
GG619_RS13495	COG1380	Effector of murein hydrolase LrgA
GG619_RS13500	COG3279	Response regulator of the LytR AlgR family
GG619_RS13505	COG3275	phosphorelay sensor kinase activity
GG619_RS13510	COG1011	Hydrolase
GG619_RS13525	COG0398	Pfam SNARE associated Golgi protein
GG619_RS13530	COG1484	DNA-dependent DNA replication
GG619_RS13535	COG3611	Membrane attachment protein
GG619_RS13550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GG619_RS13555	COG1733	regulation of RNA biosynthetic process
GG619_RS13560	COG2814	Major facilitator Superfamily
GG619_RS13565	COG0656	L-ascorbic acid biosynthetic process
GG619_RS13570	COG0237	dephospho-CoA kinase activity
GG619_RS13575	COG1971	Probably functions as a manganese efflux pump
GG619_RS13580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GG619_RS13585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GG619_RS13585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GG619_RS13590	COG5002	protein histidine kinase activity
GG619_RS13595	COG0745	RESPONSE REGULATOR receiver
GG619_RS13605	COG0538	isocitrate dehydrogenase activity
GG619_RS13610	COG0372	Belongs to the citrate synthase family
GG619_RS13625	COG0628	permease
GG619_RS13630	COG3030	protein affecting phage T7 exclusion by the F plasmid
GG619_RS13635	COG0469	pyruvate kinase activity
GG619_RS13655	COG0281	malic enzyme
GG619_RS13660	COG0587	DNA-directed DNA polymerase activity
GG619_RS13680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GG619_RS13690	COG4109	DRTGG domain
GG619_RS13700	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS13715	COG0521	Mo-molybdopterin cofactor biosynthetic process
GG619_RS13725	COG0827	DNA restriction-modification system
GG619_RS13730	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GG619_RS13735	COG3874	Sporulation protein YtfJ
GG619_RS13745	COG1714	RDD family
GG619_RS13750	COG0616	signal peptide processing
GG619_RS13755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GG619_RS13760	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GG619_RS13765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GG619_RS13780	COG1104	cysteine desulfurase activity
GG619_RS13785	COG1114	Component of the transport system for branched-chain amino acids
GG619_RS13795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GG619_RS13800	COG1309	transcriptional regulator
GG619_RS13805	COG1956	GAF domain-containing protein
GG619_RS13810	COG2203	Gaf domain
GG619_RS13810	COG2199	diguanylate cyclase activity
GG619_RS13825	COG1012	belongs to the aldehyde dehydrogenase family
GG619_RS13830	COG4282	regulation of fungal-type cell wall biogenesis
GG619_RS13835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GG619_RS13835	COG1017	nitric oxide dioxygenase activity
GG619_RS13845	COG0693	protein deglycase activity
GG619_RS13860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GG619_RS13865	COG1378	Sugar-specific transcriptional regulator TrmB
GG619_RS13885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GG619_RS13890	COG0454	-acetyltransferase
GG619_RS13895	COG0517	IMP dehydrogenase activity
GG619_RS13900	COG0123	including yeast histone deacetylase and acetoin utilization protein
GG619_RS13905	COG1360	Flagellar Motor Protein
GG619_RS13910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GG619_RS13915	COG1609	Transcriptional regulator
GG619_RS13920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GG619_RS13920	COG1605	Chorismate mutase
GG619_RS13925	COG3118	belongs to the thioredoxin family
GG619_RS13930	COG4980	gas vesicle protein
GG619_RS13935	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GG619_RS13945	COG1674	ftsk spoiiie
GG619_RS13950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GG619_RS13960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GG619_RS13970	COG1363	Peptidase, m42
GG619_RS13975	COG5584	Small secreted protein
GG619_RS13980	COG0281	malic enzyme
GG619_RS13985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GG619_RS14000	COG0510	thiamine kinase activity
GG619_RS14005	COG1597	lipid kinase activity
GG619_RS14015	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GG619_RS14020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GG619_RS14025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GG619_RS14030	COG2252	PERMEase
GG619_RS14035	COG4473	ABC transporter
GG619_RS14040	COG1131	(ABC) transporter
GG619_RS14045	COG1349	DNA-binding transcription factor activity
GG619_RS14050	COG1187	pseudouridine synthase activity
GG619_RS14055	COG2244	polysaccharide biosynthetic process
GG619_RS14060	COG2081	HI0933 family
GG619_RS14065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GG619_RS14075	COG1609	Transcriptional regulator
GG619_RS14080	COG1653	transport
GG619_RS14085	COG1175	transmembrane transport
GG619_RS14090	COG0395	ABC-type sugar transport system, permease component
GG619_RS14095	COG1486	melibiose metabolic process
GG619_RS14105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GG619_RS14120	COG1366	Belongs to the anti-sigma-factor antagonist family
GG619_RS14120	COG2202	Pas domain
GG619_RS14125	COG2814	Major facilitator Superfamily
GG619_RS14130	COG5522	Integral membrane protein (intg_mem_TP0381)
GG619_RS14135	COG0577	efflux transmembrane transporter activity
GG619_RS14140	COG1136	(ABC) transporter
GG619_RS14145	COG2205	protein histidine kinase activity
GG619_RS14150	COG0745	RESPONSE REGULATOR receiver
GG619_RS14155	COG0577	efflux transmembrane transporter activity
GG619_RS14160	COG1136	(ABC) transporter
GG619_RS14180	COG1131	(ABC) transporter
GG619_RS14185	COG1725	Transcriptional regulator
GG619_RS14195	COG0640	Transcriptional regulator
GG619_RS14200	COG0477	Major facilitator Superfamily
GG619_RS14205	COG1242	4 iron, 4 sulfur cluster binding
GG619_RS14210	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GG619_RS14220	COG0584	glycerophosphoryl diester phosphodiesterase
GG619_RS14230	COG2267	carboxylic ester hydrolase activity
GG619_RS14240	COG1113	amino acid transport
GG619_RS14245	COG0367	asparagine synthase
GG619_RS14265	COG1506	peptidase
GG619_RS14270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GG619_RS14275	COG1116	anion transmembrane transporter activity
GG619_RS14280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GG619_RS14285	COG0494	nUDIX hydrolase
GG619_RS14290	COG4824	toxin secretion phage lysis holin
GG619_RS14295	COG0783	Belongs to the Dps family
GG619_RS14320	COG0288	reversible hydration of carbon dioxide
GG619_RS14330	COG1271	oxidase subunit
GG619_RS14335	COG1294	oxidase, subunit
GG619_RS14350	COG4948	Mandelate Racemase Muconate Lactonizing
GG619_RS14360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GG619_RS14365	COG0596	Alpha beta hydrolase
GG619_RS14375	COG1169	isochorismate synthase
GG619_RS14380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GG619_RS14385	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GG619_RS14510	COG3859	Proton-coupled thiamine transporter YuaJ
GG619_RS14515	COG2268	Band 7 protein
GG619_RS14520	COG1585	Membrane protein implicated in regulation of membrane protease activity
GG619_RS14525	COG2318	DinB family
GG619_RS14535	COG1454	alcohol dehydrogenase
GG619_RS14540	COG1012	belongs to the aldehyde dehydrogenase family
GG619_RS14545	COG1510	regulation of RNA biosynthetic process
GG619_RS14555	COG0569	domain protein
GG619_RS14560	COG1705	Flagellar rod assembly protein muramidase FlgJ
GG619_RS14565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GG619_RS14565	COG1017	nitric oxide dioxygenase activity
GG619_RS14590	COG0628	permease
GG619_RS14595	COG0673	inositol 2-dehydrogenase activity
GG619_RS14600	COG0693	protein deglycase activity
GG619_RS14605	COG0840	transmembrane signaling receptor activity
GG619_RS14610	COG0840	transmembrane signaling receptor activity
GG619_RS14615	COG0840	transmembrane signaling receptor activity
GG619_RS14620	COG0840	transmembrane signaling receptor activity
GG619_RS14635	COG2070	2-Nitropropane dioxygenase
GG619_RS14640	COG0432	Pfam Uncharacterised protein family UPF0047
GG619_RS14645	COG0366	Alpha amylase catalytic
GG619_RS14650	COG1253	flavin adenine dinucleotide binding
GG619_RS14655	COG2738	Putative neutral zinc metallopeptidase
GG619_RS14670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GG619_RS14695	COG1335	isochorismatase
GG619_RS14700	COG1979	alcohol dehydrogenase
GG619_RS14705	COG1979	alcohol dehydrogenase
GG619_RS14710	COG2155	Conserved Protein
GG619_RS14715	COG1098	S1 RNA binding domain
GG619_RS14720	COG0436	Aminotransferase
GG619_RS14725	COG1522	sequence-specific DNA binding
GG619_RS14730	COG2267	carboxylic ester hydrolase activity
GG619_RS14740	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GG619_RS14745	COG2205	protein histidine kinase activity
GG619_RS14755	COG5018	Exonuclease
GG619_RS14760	COG2814	Major facilitator Superfamily
GG619_RS14765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GG619_RS14770	COG3011	Protein conserved in bacteria
GG619_RS14780	COG3290	protein histidine kinase activity
GG619_RS14785	COG4565	transcriptional regulatory protein
GG619_RS14790	COG1744	ABC transporter substrate-binding protein PnrA-like
GG619_RS14795	COG3845	ABC transporter
GG619_RS14800	COG4603	Belongs to the binding-protein-dependent transport system permease family
GG619_RS14805	COG1079	Belongs to the binding-protein-dependent transport system permease family
GG619_RS14815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GG619_RS14815	COG2111	Na H antiporter
GG619_RS14820	COG2111	Na H antiporter
GG619_RS14825	COG1006	Multisubunit Na H antiporter MnhC subunit
GG619_RS14830	COG0651	ATP synthesis coupled electron transport
GG619_RS14835	COG1863	multisubunit Na H antiporter MnhE subunit
GG619_RS14840	COG2212	antiporter activity
GG619_RS14845	COG1320	monovalent cation:proton antiporter activity
GG619_RS14850	COG2050	protein possibly involved in aromatic compounds catabolism
GG619_RS14855	COG2197	response regulator
GG619_RS14860	COG4585	Histidine kinase
GG619_RS14870	COG0142	geranyltranstransferase activity
GG619_RS14885	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GG619_RS14890	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GG619_RS14895	COG1335	isochorismatase
GG619_RS14900	COG5506	Protein of unknown function (DUF1694)
GG619_RS14915	COG0628	permease
GG619_RS14925	COG1418	mRNA catabolic process
GG619_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS14940	COG1511	domain protein
GG619_RS14945	COG0433	COG0433 Predicted ATPase
GG619_RS14945	COG1674	ftsk spoiiie
GG619_RS14950	COG4499	WXG100 protein secretion system (Wss), protein YukC
GG619_RS14955	COG5417	Belongs to the EsaB family
GG619_RS14960	COG4842	Belongs to the WXG100 family
GG619_RS14965	COG2508	Transcriptional regulator
GG619_RS14965	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GG619_RS14970	COG0686	Belongs to the AlaDH PNT family
GG619_RS14975	COG5634	Uncharacterized conserved protein (DUF2278)
GG619_RS14980	COG3251	PFAM MbtH domain protein
GG619_RS14985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GG619_RS14990	COG3433	isochorismatase activity
GG619_RS14990	COG1535	isochorismatase
GG619_RS14995	COG1021	2,3-dihydroxybenzoate-AMP ligase
GG619_RS15000	COG1169	isochorismate synthase
GG619_RS15005	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS15010	COG2819	hydrolase of the alpha beta superfamily
GG619_RS15015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GG619_RS15020	COG1268	BioY protein
GG619_RS15025	COG2056	Na+-H+ antiporter family
GG619_RS15035	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GG619_RS15040	COG3584	3D domain protein
GG619_RS15055	COG1252	NADH dehydrogenase
GG619_RS15080	COG1131	(ABC) transporter
GG619_RS15100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GG619_RS15105	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GG619_RS15110	COG0316	Belongs to the HesB IscA family
GG619_RS15120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GG619_RS15130	COG1252	NADH dehydrogenase
GG619_RS15135	COG4837	Protein of unknown function (DUF1462)
GG619_RS15140	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GG619_RS15145	COG4946	Tricorn protease homolog
GG619_RS15145	COG1506	peptidase
GG619_RS15145	COG0823	Involved in the tonB-independent uptake of proteins
GG619_RS15155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GG619_RS15160	COG0460	homoserine dehydrogenase
GG619_RS15165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GG619_RS15170	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GG619_RS15175	COG0647	UMP catabolic process
GG619_RS15180	COG2445	Protein of unknown function DUF86
GG619_RS15185	COG4470	Protein conserved in bacteria
GG619_RS15195	COG0739	heme binding
GG619_RS15205	COG0737	Belongs to the 5'-nucleotidase family
GG619_RS15210	COG0730	response to heat
GG619_RS15215	COG1801	Protein of unknown function DUF72
GG619_RS15230	COG2508	Transcriptional regulator
GG619_RS15255	COG2814	Major facilitator Superfamily
GG619_RS15260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GG619_RS15265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GG619_RS15270	COG2356	endonuclease I
GG619_RS15275	COG3842	ATPase activity
GG619_RS15280	COG2188	Transcriptional regulator
GG619_RS15285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GG619_RS15290	COG0395	ABC-type sugar transport system, permease component
GG619_RS15295	COG1175	transmembrane transport
GG619_RS15300	COG1653	transport
GG619_RS15305	COG2222	sugar isomerase
GG619_RS15310	COG0789	Transcriptional regulator
GG619_RS15325	COG0322	excinuclease ABC activity
GG619_RS15330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GG619_RS15335	COG2226	methyltransferase
GG619_RS15345	COG3409	Peptidoglycan-binding domain 1 protein
GG619_RS15350	COG0719	Fe-S assembly protein
GG619_RS15355	COG0822	iron-sulfur transferase activity
GG619_RS15360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GG619_RS15365	COG0719	Fe-S assembly protein
GG619_RS15370	COG0396	ATPase activity
GG619_RS15380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GG619_RS15385	COG1464	Belongs to the NlpA lipoprotein family
GG619_RS15390	COG2011	ABC-type metal ion transport system permease component
GG619_RS15395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GG619_RS15405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GG619_RS15410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GG619_RS15425	COG1393	Belongs to the ArsC family
GG619_RS15430	COG1960	acyl-CoA dehydrogenase activity
GG619_RS15435	COG0183	Belongs to the thiolase family
GG619_RS15440	COG1024	Enoyl-CoA hydratase
GG619_RS15440	COG1250	3-hydroxyacyl-CoA dehydrogenase
GG619_RS15460	COG5577	PFAM Coat F domain
GG619_RS15465	COG1846	Transcriptional regulator
GG619_RS15470	COG0477	Major facilitator Superfamily
GG619_RS15475	COG1942	4-Oxalocrotonate Tautomerase
GG619_RS15480	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS15485	COG0583	DNA-binding transcription factor activity
GG619_RS15495	COG0583	DNA-binding transcription factor activity
GG619_RS15515	COG1120	ATPase activity
GG619_RS15530	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS15535	COG0783	Belongs to the Dps family
GG619_RS15540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GG619_RS15545	COG0745	RESPONSE REGULATOR receiver
GG619_RS15550	COG2205	protein histidine kinase activity
GG619_RS15550	COG2770	Histidine kinase
GG619_RS15560	COG1309	transcriptional regulator
GG619_RS15565	COG0114	fumarate hydratase activity
GG619_RS15575	COG0697	spore germination
GG619_RS15580	COG0814	amino acid
GG619_RS15590	COG2197	response regulator
GG619_RS15595	COG4585	Histidine kinase
GG619_RS15600	COG4758	membrane
GG619_RS15605	COG3595	metallopeptidase activity
GG619_RS15610	COG1842	Phage shock protein A
GG619_RS15615	COG4758	membrane
GG619_RS15620	COG2814	Major facilitator Superfamily
GG619_RS15625	COG2096	Adenosyltransferase
GG619_RS15630	COG1120	ATPase activity
GG619_RS15635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GG619_RS15640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GG619_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS15650	COG3386	PFAM SMP-30 Gluconolaconase
GG619_RS15655	COG2205	protein histidine kinase activity
GG619_RS15660	COG0745	RESPONSE REGULATOR receiver
GG619_RS15670	COG1191	sigma factor activity
GG619_RS15680	COG2140	Oxalate decarboxylase
GG619_RS15690	COG1120	ATPase activity
GG619_RS15695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GG619_RS15700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GG619_RS15705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GG619_RS15710	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GG619_RS15715	COG0531	amino acid
GG619_RS15725	COG1988	membrane-bound metal-dependent
GG619_RS15730	COG1368	sulfuric ester hydrolase activity
GG619_RS15735	COG1910	domain protein
GG619_RS15740	COG0725	ABC transporter, periplasmic molybdate-binding protein
GG619_RS15745	COG4149	molybdate abc transporter
GG619_RS15750	COG2197	response regulator
GG619_RS15755	COG3850	Histidine kinase
GG619_RS15760	COG1131	(ABC) transporter
GG619_RS15770	COG0842	Transport permease protein
GG619_RS15775	COG0656	L-ascorbic acid biosynthetic process
GG619_RS15795	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GG619_RS15800	COG3973	AAA domain
GG619_RS15805	COG2860	membrane
GG619_RS15815	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GG619_RS15820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GG619_RS15825	COG2217	Heavy metal translocating P-type atpase
GG619_RS15830	COG2217	Heavy metal translocating P-type atpase
GG619_RS15835	COG2608	mercury ion transmembrane transporter activity
GG619_RS15840	COG1937	Protein conserved in bacteria
GG619_RS15845	COG0673	inositol 2-dehydrogenase activity
GG619_RS15855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GG619_RS15860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GG619_RS15865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GG619_RS15870	COG1126	abc transporter atp-binding protein
GG619_RS15875	COG0765	amino acid transport
GG619_RS15880	COG0765	amino acid transport
GG619_RS15885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GG619_RS15890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GG619_RS15895	COG0454	-acetyltransferase
GG619_RS15900	COG0583	DNA-binding transcription factor activity
GG619_RS15905	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS15910	COG2732	(Barnase) inhibitor
GG619_RS15915	COG2732	(Barnase) inhibitor
GG619_RS15930	COG0557	exoribonuclease II activity
GG619_RS15935	COG1647	Serine aminopeptidase, S33
GG619_RS15940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GG619_RS15945	COG1476	TRANSCRIPTIONal
GG619_RS15950	COG1396	sequence-specific DNA binding
GG619_RS15955	COG1396	sequence-specific DNA binding
GG619_RS15960	COG1733	regulation of RNA biosynthetic process
GG619_RS15985	COG1131	(ABC) transporter
GG619_RS15990	COG1174	glycine betaine transport
GG619_RS15995	COG1732	Glycine betaine
GG619_RS16000	COG1174	glycine betaine transport
GG619_RS16005	COG1125	glycine betaine transport
GG619_RS16005	COG0517	IMP dehydrogenase activity
GG619_RS16010	COG1510	regulation of RNA biosynthetic process
GG619_RS16015	COG1174	glycine betaine transport
GG619_RS16020	COG1732	Glycine betaine
GG619_RS16025	COG1174	glycine betaine transport
GG619_RS16030	COG0517	IMP dehydrogenase activity
GG619_RS16030	COG1125	glycine betaine transport
GG619_RS16035	COG1510	regulation of RNA biosynthetic process
GG619_RS16040	COG2095	MarC family integral membrane protein
GG619_RS16045	COG3064	Membrane
GG619_RS16050	COG4640	response to antibiotic
GG619_RS16055	COG0456	acetyltransferase
GG619_RS16070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GG619_RS16085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GG619_RS16090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GG619_RS16095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GG619_RS16105	COG2234	aminopeptidase activity
GG619_RS16125	COG0126	phosphoglycerate kinase activity
GG619_RS16130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GG619_RS16135	COG2390	Transcriptional regulator
GG619_RS16140	COG2814	Major facilitator Superfamily
GG619_RS16145	COG1609	Transcriptional regulator
GG619_RS16155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GG619_RS16160	COG0583	DNA-binding transcription factor activity
GG619_RS16165	COG0697	spore germination
GG619_RS16170	COG1113	amino acid transport
GG619_RS16180	COG1609	Transcriptional regulator
GG619_RS16190	COG0561	phosphatase activity
GG619_RS16195	COG1737	Transcriptional regulator
GG619_RS16200	COG1070	Carbohydrate kinase
GG619_RS16225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GG619_RS16230	COG2186	Transcriptional regulator
GG619_RS16235	COG1620	l-lactate permease
GG619_RS16240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GG619_RS16250	COG5039	Polysaccharide pyruvyl transferase
GG619_RS16255	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GG619_RS16260	COG0110	maltose O-acetyltransferase activity
GG619_RS16265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GG619_RS16270	COG2244	polysaccharide biosynthetic process
GG619_RS16275	COG1216	Glycosyl transferase, family 2
GG619_RS16280	COG5039	Polysaccharide pyruvyl transferase
GG619_RS16285	COG1216	Glycosyl transferase, family 2
GG619_RS16295	COG0438	transferase activity, transferring glycosyl groups
GG619_RS16300	COG1215	transferase activity, transferring glycosyl groups
GG619_RS16305	COG0438	transferase activity, transferring glycosyl groups
GG619_RS16310	COG1086	Polysaccharide biosynthesis protein
GG619_RS16315	COG0489	protein tyrosine kinase activity
GG619_RS16320	COG3944	biosynthesis protein
GG619_RS16325	COG1396	sequence-specific DNA binding
GG619_RS16330	COG2272	Belongs to the type-B carboxylesterase lipase family
GG619_RS16335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GG619_RS16340	COG2364	Membrane
GG619_RS16345	COG0456	acetyltransferase
GG619_RS16350	COG3479	Phenolic acid decarboxylase
GG619_RS16415	COG2223	nitrite transmembrane transporter activity
GG619_RS16420	COG1609	Transcriptional regulator
GG619_RS16430	COG0583	DNA-binding transcription factor activity
GG619_RS16435	COG2828	Protein conserved in bacteria
GG619_RS16440	COG0477	Major facilitator Superfamily
GG619_RS16440	COG2814	Major facilitator Superfamily
GG619_RS16445	COG1611	Belongs to the LOG family
GG619_RS16450	COG1694	Mazg nucleotide pyrophosphohydrolase
GG619_RS16455	COG0659	secondary active sulfate transmembrane transporter activity
GG619_RS16460	COG0288	reversible hydration of carbon dioxide
GG619_RS16465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GG619_RS16470	COG4290	ribonuclease
GG619_RS16475	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GG619_RS16480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GG619_RS16490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GG619_RS16500	COG1051	belongs to the nudix hydrolase family
GG619_RS16505	COG0492	ferredoxin-NADP+ reductase activity
GG619_RS16510	COG3883	PFAM NLP P60 protein
GG619_RS16510	COG0791	NLP P60 protein
GG619_RS16515	COG0457	Tetratricopeptide repeat
GG619_RS16520	COG5002	protein histidine kinase activity
GG619_RS16525	COG0745	RESPONSE REGULATOR receiver
GG619_RS16535	COG1132	(ABC) transporter
GG619_RS16540	COG0140	phosphoribosyl-ATP diphosphatase activity
GG619_RS16540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GG619_RS16565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GG619_RS16580	COG4990	cell redox homeostasis
GG619_RS16585	COG0110	maltose O-acetyltransferase activity
GG619_RS16605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GG619_RS16615	COG2188	Transcriptional regulator
GG619_RS16620	COG1309	transcriptional regulator
GG619_RS16625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GG619_RS16630	COG1950	PFAM Membrane protein of
GG619_RS16635	COG1983	PspC domain protein
GG619_RS16640	COG3595	metallopeptidase activity
GG619_RS16655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GG619_RS16665	COG4897	Protein conserved in bacteria
GG619_RS16670	COG3848	Pyruvate phosphate dikinase
GG619_RS16670	COG0574	Belongs to the PEP-utilizing enzyme family
GG619_RS16675	COG1309	transcriptional regulator
GG619_RS16680	COG2814	Major facilitator Superfamily
GG619_RS16730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GG619_RS16740	COG3409	Peptidoglycan-binding domain 1 protein
GG619_RS16740	COG0793	Belongs to the peptidase S41A family
GG619_RS16745	COG3420	alginic acid biosynthetic process
GG619_RS16750	COG2177	Part of the ABC transporter FtsEX involved in
GG619_RS16755	COG2884	Cell division ATP-binding protein ftsE
GG619_RS16760	COG2010	Cytochrome c
GG619_RS16765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GG619_RS16780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GG619_RS16795	COG1516	flagellar protein fliS
GG619_RS16800	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GG619_RS16805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GG619_RS16825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GG619_RS16830	COG4786	Flagellar basal body rod
GG619_RS16830	COG1256	bacterial-type flagellum assembly
GG619_RS16835	COG3418	PFAM FlgN family protein
GG619_RS16840	COG2747	anti-sigma28 factor FlgM
GG619_RS16850	COG1040	competence protein
GG619_RS16860	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GG619_RS16865	COG1307	EDD domain protein, DegV family
GG619_RS16870	COG2197	response regulator
GG619_RS16875	COG4585	Histidine kinase
GG619_RS16880	COG1739	Uncharacterized protein family UPF0029
GG619_RS16885	COG1316	TRANSCRIPTIONal
GG619_RS16890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GG619_RS16895	COG0438	transferase activity, transferring glycosyl groups
GG619_RS16900	COG1215	transferase activity, transferring glycosyl groups
GG619_RS16905	COG3206	protein involved in exopolysaccharide biosynthesis
GG619_RS16910	COG3307	-O-antigen
GG619_RS16915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GG619_RS16920	COG0297	glycogen (starch) synthase activity
GG619_RS16920	COG0438	transferase activity, transferring glycosyl groups
GG619_RS16925	COG2244	polysaccharide biosynthetic process
GG619_RS16935	COG2247	cell wall binding repeat
GG619_RS16935	COG0860	N-Acetylmuramoyl-L-alanine amidase
GG619_RS16940	COG2385	sporulation resulting in formation of a cellular spore
GG619_RS16940	COG2247	cell wall binding repeat
GG619_RS16950	COG1316	TRANSCRIPTIONal
GG619_RS16955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GG619_RS16960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GG619_RS16965	COG1134	teichoic acid transport
GG619_RS16970	COG1682	transport, permease protein
GG619_RS16975	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GG619_RS16985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GG619_RS16990	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GG619_RS16995	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GG619_RS17000	COG4193	domain, Protein
GG619_RS17005	COG1482	cell wall glycoprotein biosynthetic process
GG619_RS17010	COG0697	spore germination
GG619_RS17015	COG0814	amino acid
GG619_RS17025	COG1215	transferase activity, transferring glycosyl groups
GG619_RS17030	COG2814	Major facilitator Superfamily
GG619_RS17035	COG1316	TRANSCRIPTIONal
GG619_RS17040	COG0561	phosphatase activity
GG619_RS17045	COG2433	Pfam Transposase IS66
GG619_RS17050	COG0791	NLP P60 protein
GG619_RS17060	COG2843	Capsule synthesis protein
GG619_RS17070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GG619_RS17075	COG0697	spore germination
GG619_RS17080	COG0814	amino acid
GG619_RS17090	COG1609	Transcriptional regulator
GG619_RS17095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GG619_RS17105	COG1129	ABC transporter
GG619_RS17110	COG1172	Belongs to the binding-protein-dependent transport system permease family
GG619_RS17115	COG1879	ABC-type sugar transport system periplasmic component
GG619_RS17120	COG3103	Sh3 type 3 domain protein
GG619_RS17125	COG2249	NAD(P)H dehydrogenase (quinone) activity
GG619_RS17130	COG3527	Alpha-acetolactate decarboxylase
GG619_RS17135	COG0028	Belongs to the TPP enzyme family
GG619_RS17140	COG0583	DNA-binding transcription factor activity
GG619_RS17145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GG619_RS17160	COG5337	Spore coat protein CotH
GG619_RS17170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GG619_RS17180	COG0405	Gamma-glutamyltransferase
GG619_RS17185	COG1522	sequence-specific DNA binding
GG619_RS17190	COG2059	Chromate
GG619_RS17195	COG2059	Chromate
GG619_RS17250	COG5444	nuclease activity
GG619_RS17265	COG3878	Protein conserved in bacteria
GG619_RS17270	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GG619_RS17275	COG4464	protein tyrosine phosphatase activity
GG619_RS17280	COG0489	protein tyrosine kinase activity
GG619_RS17285	COG3944	biosynthesis protein
GG619_RS17295	COG4715	Zinc finger, swim domain protein
GG619_RS17300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GG619_RS17305	COG0561	phosphatase activity
GG619_RS17310	COG1349	DNA-binding transcription factor activity
GG619_RS17315	COG0629	single-stranded DNA binding
GG619_RS17340	COG0457	Tetratricopeptide repeat
GG619_RS17345	COG4786	Flagellar basal body rod
GG619_RS17350	COG4786	Flagellar basal body rod
GG619_RS17355	COG1077	Cell shape determining protein MreB Mrl
GG619_RS17360	COG1609	Transcriptional regulator
GG619_RS17365	COG1846	Transcriptional regulator
GG619_RS17370	COG2814	Major facilitator Superfamily
GG619_RS17375	COG1953	Uracil, thiamine, allantoin
GG619_RS17380	COG0477	Major facilitator Superfamily
GG619_RS17385	COG1335	isochorismatase
GG619_RS17390	COG0004	ammonium transporteR
GG619_RS17395	COG0347	Belongs to the P(II) protein family
GG619_RS17400	COG0772	Belongs to the SEDS family
GG619_RS17405	COG0671	phosphoesterase, PA-phosphatase related
GG619_RS17415	COG0739	heme binding
GG619_RS17420	COG1247	-acetyltransferase
GG619_RS17435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GG619_RS17445	COG0726	polysaccharide deacetylase
GG619_RS17450	COG1959	2 iron, 2 sulfur cluster binding
GG619_RS17465	COG0831	urea catabolic process
GG619_RS17475	COG1994	Peptidase M50
GG619_RS17480	COG0457	Tetratricopeptide repeat
GG619_RS17490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GG619_RS17495	COG2304	oxidoreductase activity
GG619_RS17500	COG2304	oxidoreductase activity
GG619_RS17505	COG2385	sporulation resulting in formation of a cellular spore
GG619_RS17510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GG619_RS17520	COG4836	Membrane
GG619_RS17590	COG0698	ribose 5-phosphate isomerase
GG619_RS17595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GG619_RS17605	COG0009	L-threonylcarbamoyladenylate synthase
GG619_RS17610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GG619_RS17630	COG2890	protein-(glutamine-N5) methyltransferase activity
GG619_RS17635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GG619_RS17640	COG0346	lactoylglutathione lyase activity
GG619_RS17645	COG0789	Transcriptional regulator
GG619_RS17650	COG0679	Auxin Efflux Carrier
GG619_RS17655	COG0281	malic enzyme
GG619_RS17670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GG619_RS17675	COG1494	fructose-1,6-bisphosphatase
GG619_RS17680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GG619_RS17690	COG0191	fructose-bisphosphate aldolase activity
GG619_RS17695	COG2204	response regulator
GG619_RS17700	COG4821	SIS domain
GG619_RS17715	COG2181	nitrate reductase activity
GG619_RS17715	COG0247	lactate metabolic process
GG619_RS17720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GG619_RS17735	COG1132	(ABC) transporter
GG619_RS17740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GG619_RS17750	COG2181	nitrate reductase activity
GG619_RS17755	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GG619_RS17760	COG1140	nitrate reductase beta subunit
GG619_RS17765	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GG619_RS17770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GG619_RS17780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GG619_RS17785	COG2223	nitrite transmembrane transporter activity
GG619_RS17795	COG4506	Protein conserved in bacteria
GG619_RS17805	COG3391	amine dehydrogenase activity
GG619_RS17810	COG3391	amine dehydrogenase activity
GG619_RS17815	COG0457	Tetratricopeptide repeat
GG619_RS17860	COG0010	Belongs to the arginase family
GG619_RS17865	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GG619_RS17870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GG619_RS17885	COG1994	Peptidase M50
GG619_RS17890	COG1942	4-Oxalocrotonate Tautomerase
GG619_RS17895	COG1846	Transcriptional regulator
GG619_RS17900	COG0531	amino acid
GG619_RS17905	COG3465	dGTPase activity
GG619_RS17910	COG1078	dGTPase activity
GG619_RS17925	COG1695	Transcriptional regulator
GG619_RS17935	COG1131	(ABC) transporter
GG619_RS17940	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GG619_RS17970	COG0583	DNA-binding transcription factor activity
GG619_RS17975	COG2855	membrane
GG619_RS17980	COG0280	phosphate acetyltransferase
GG619_RS17990	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS17995	COG0436	Aminotransferase
GG619_RS18025	COG2814	Major facilitator Superfamily
GG619_RS18030	COG2814	Major facilitator Superfamily
GG619_RS18035	COG0833	amino acid
GG619_RS18040	COG4187	Peptidase family M20/M25/M40
GG619_RS18045	COG1012	belongs to the aldehyde dehydrogenase family
GG619_RS18050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GG619_RS18060	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GG619_RS18065	COG1091	dTDP-4-dehydrorhamnose reductase activity
GG619_RS18070	COG1088	dTDP-glucose 4,6-dehydratase activity
GG619_RS18075	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GG619_RS18080	COG3980	spore coat polysaccharide biosynthesis protein
GG619_RS18085	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GG619_RS18090	COG2089	acid synthase
GG619_RS18095	COG0456	acetyltransferase
GG619_RS18100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GG619_RS18105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GG619_RS18110	COG0463	Glycosyl transferase, family 2
GG619_RS18120	COG2363	Small membrane protein
GG619_RS18125	COG2233	PERMEase
GG619_RS18140	COG1216	Glycosyl transferase, family 2
GG619_RS18150	COG0351	phosphomethylpyrimidine kinase
GG619_RS18160	COG1621	beta-fructofuranosidase activity
GG619_RS18165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GG619_RS18165	COG1263	PTS System
GG619_RS18170	COG3711	transcriptional antiterminator
GG619_RS18180	COG1404	Belongs to the peptidase S8 family
GG619_RS18185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GG619_RS18190	COG0778	Nitroreductase
GG619_RS18195	COG0772	Belongs to the SEDS family
GG619_RS18200	COG0454	-acetyltransferase
GG619_RS18220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GG619_RS18225	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GG619_RS18230	COG2261	transglycosylase associated protein
GG619_RS18235	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GG619_RS18240	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GG619_RS18245	COG2246	polysaccharide biosynthetic process
GG619_RS18250	COG1309	transcriptional regulator
GG619_RS18270	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GG619_RS18275	COG2837	iron assimilation
GG619_RS18280	COG2822	iron ion transport
GG619_RS18295	COG0583	DNA-binding transcription factor activity
GG619_RS18305	COG1346	cytolysis
GG619_RS18310	COG4895	conserved protein (DUF2196)
GG619_RS18315	COG0789	Transcriptional regulator
GG619_RS18320	COG5504	Zn-dependent protease
GG619_RS18325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GG619_RS18330	COG0346	lactoylglutathione lyase activity
GG619_RS18335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GG619_RS18340	COG1404	Belongs to the peptidase S8 family
GG619_RS18345	COG1442	glycosyl transferase family 8
GG619_RS18350	COG2357	RelA SpoT domain protein
GG619_RS18355	COG1575	Belongs to the MenA family. Type 1 subfamily
GG619_RS18370	COG1696	Membrane protein involved in D-alanine export
GG619_RS18380	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GG619_RS18385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GG619_RS18390	COG1486	melibiose metabolic process
GG619_RS18395	COG1447	Phosphotransferase system cellobiose-specific component IIA
GG619_RS18400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GG619_RS18405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GG619_RS18410	COG3711	transcriptional antiterminator
GG619_RS18410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GG619_RS18420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GG619_RS18425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GG619_RS18430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GG619_RS18435	COG0640	Transcriptional regulator
GG619_RS18440	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GG619_RS18445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GG619_RS18450	COG1447	Phosphotransferase system cellobiose-specific component IIA
GG619_RS18455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GG619_RS18460	COG2723	6-phospho-beta-galactosidase activity
GG619_RS18465	COG1940	carbohydrate kinase activity
GG619_RS18470	COG1482	cell wall glycoprotein biosynthetic process
GG619_RS18480	COG0753	catalase activity
GG619_RS18485	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GG619_RS18490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GG619_RS18495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GG619_RS18500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GG619_RS18505	COG4988	ABC transporter
GG619_RS18510	COG1294	oxidase, subunit
GG619_RS18515	COG1271	oxidase subunit
GG619_RS18520	COG3493	citrate carrier protein
GG619_RS18525	COG0726	polysaccharide deacetylase
GG619_RS18530	COG3842	ATPase activity
GG619_RS18535	COG2508	Transcriptional regulator
GG619_RS18540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GG619_RS18550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GG619_RS18560	COG4894	glucomannan catabolic process
GG619_RS18565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GG619_RS18570	COG0500	methyltransferase
GG619_RS18575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GG619_RS18595	COG0753	catalase activity
GG619_RS18595	COG0693	protein deglycase activity
GG619_RS18600	COG2851	Citrate transporter
GG619_RS18605	COG2273	Hydrolase Family 16
GG619_RS18610	COG3711	transcriptional antiterminator
GG619_RS18615	COG2270	Major facilitator Superfamily
GG619_RS18620	COG0513	Belongs to the DEAD box helicase family
GG619_RS18670	COG3209	COG3209 Rhs family protein
GG619_RS18680	COG0697	spore germination
GG619_RS18685	COG0589	response to stress
GG619_RS18700	COG0494	nUDIX hydrolase
GG619_RS18705	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GG619_RS18710	COG3507	Belongs to the glycosyl hydrolase 43 family
GG619_RS18735	COG0010	Belongs to the arginase family
GG619_RS18740	COG0833	amino acid
GG619_RS18745	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GG619_RS18750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GG619_RS18760	COG2390	Transcriptional regulator
GG619_RS18765	COG0561	phosphatase activity
GG619_RS18795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GG619_RS18800	COG5294	Protein conserved in bacteria
GG619_RS18805	COG0577	efflux transmembrane transporter activity
GG619_RS18810	COG1136	(ABC) transporter
GG619_RS18815	COG2205	protein histidine kinase activity
GG619_RS18820	COG0745	RESPONSE REGULATOR receiver
GG619_RS18825	COG2205	protein histidine kinase activity
GG619_RS18830	COG0745	RESPONSE REGULATOR receiver
GG619_RS18860	COG1082	Xylose isomerase domain protein TIM barrel
GG619_RS18870	COG2814	Major facilitator Superfamily
GG619_RS18900	COG1349	DNA-binding transcription factor activity
GG619_RS18905	COG0667	Aldo Keto reductase
GG619_RS18910	COG2814	Major facilitator Superfamily
GG619_RS18925	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS18930	COG2197	response regulator
GG619_RS18935	COG4585	Histidine kinase
GG619_RS18940	COG3239	Fatty acid desaturase
GG619_RS18945	COG1309	transcriptional regulator
GG619_RS18950	COG1012	belongs to the aldehyde dehydrogenase family
GG619_RS18955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GG619_RS18965	COG0640	Transcriptional regulator
GG619_RS18970	COG2814	Major facilitator Superfamily
GG619_RS18975	COG1714	RDD family
GG619_RS18985	COG0450	alkyl hydroperoxide reductase
GG619_RS18990	COG3634	alkyl hydroperoxide reductase activity
GG619_RS18995	COG3177	Filamentation induced by cAMP protein fic
GG619_RS19000	COG1113	amino acid transport
GG619_RS19010	COG2080	2 iron, 2 sulfur cluster binding
GG619_RS19025	COG2068	MobA-Related Protein
GG619_RS19030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GG619_RS19090	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GG619_RS19095	COG0667	Aldo Keto reductase
GG619_RS19100	COG0456	acetyltransferase
GG619_RS19105	COG0457	Tetratricopeptide repeat
GG619_RS19110	COG0010	Belongs to the arginase family
GG619_RS19115	COG0833	amino acid
GG619_RS19120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GG619_RS19125	COG5658	integral membrane protein
GG619_RS19130	COG0640	Transcriptional regulator
GG619_RS19135	COG3829	transcription factor binding
GG619_RS19145	COG0488	(ABC) transporter
GG619_RS19160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GG619_RS19165	COG5002	protein histidine kinase activity
GG619_RS19165	COG3850	Histidine kinase
GG619_RS19170	COG0745	RESPONSE REGULATOR receiver
GG619_RS19175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GG619_RS19180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GG619_RS19185	COG4853	Protein conserved in bacteria
GG619_RS19190	COG4863	YycH protein
GG619_RS19195	COG5002	protein histidine kinase activity
GG619_RS19200	COG0745	RESPONSE REGULATOR receiver
GG619_RS19230	COG0346	lactoylglutathione lyase activity
GG619_RS19235	COG0305	Participates in initiation and elongation during chromosome replication
GG619_RS19255	COG3093	addiction module antidote protein HigA
GG619_RS19260	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GG619_RS19265	COG0297	glycogen (starch) synthase activity
GG619_RS19275	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GG619_RS19280	COG0438	transferase activity, transferring glycosyl groups
GG619_RS19300	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GG619_RS19305	COG4241	membrane
GG619_RS19315	COG5577	PFAM Coat F domain
GG619_RS19320	COG1733	regulation of RNA biosynthetic process
GG619_RS19330	COG0697	spore germination
GG619_RS19335	COG1621	beta-fructofuranosidase activity
GG619_RS19340	COG1621	beta-fructofuranosidase activity
GG619_RS19345	COG1802	Transcriptional regulator
GG619_RS19350	COG2318	DinB family
GG619_RS19355	COG2211	Major facilitator Superfamily
GG619_RS19360	COG0583	DNA-binding transcription factor activity
GG619_RS19375	COG0778	Nitroreductase
GG619_RS19380	COG1846	Transcriptional regulator
GG619_RS19385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GG619_RS19390	COG1846	Transcriptional regulator
GG619_RS19395	COG2153	protein acetylation
GG619_RS19405	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GG619_RS19410	COG0583	DNA-binding transcription factor activity
GG619_RS19415	COG1028	Short-chain dehydrogenase reductase Sdr
GG619_RS19420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GG619_RS19425	COG0697	spore germination
GG619_RS19430	COG1331	Highly conserved protein containing a thioredoxin domain
GG619_RS19435	COG1266	CAAX protease self-immunity
GG619_RS19440	COG2814	Major facilitator Superfamily
GG619_RS19440	COG0477	Major facilitator Superfamily
GG619_RS19445	COG0346	lactoylglutathione lyase activity
GG619_RS19450	COG1609	Transcriptional regulator
GG619_RS19455	COG0708	Exodeoxyribonuclease III
GG619_RS19460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GG619_RS19465	COG2169	Transcriptional regulator
GG619_RS19475	COG0629	single-stranded DNA binding
GG619_RS19485	COG0012	GTP binding
GG619_RS19490	COG0243	molybdopterin cofactor binding
GG619_RS19495	COG4481	Protein conserved in bacteria
GG619_RS19500	COG3949	Membrane
GG619_RS19515	COG1475	DNA binding
GG619_RS19520	COG1192	Involved in chromosome partitioning
GG619_RS19545	COG1847	R3H domain protein
GG619_RS19550	COG0706	membrane insertase activity
