locus-tag	class	description
H2N97_RS00010	COG0592	DNA-directed DNA polymerase activity
H2N97_RS00015	COG2501	S4 domain
H2N97_RS00030	COG0187	DNA topoisomerase II activity
H2N97_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H2N97_RS00070	COG0516	GMP reductase activity
H2N97_RS00070	COG0517	IMP dehydrogenase activity
H2N97_RS00075	COG1686	Belongs to the peptidase S11 family
H2N97_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
H2N97_RS00105	COG1428	Deoxynucleoside kinase
H2N97_RS00110	COG1428	Deoxynucleoside kinase
H2N97_RS00115	COG1388	LysM domain
H2N97_RS00115	COG3858	chitin binding
H2N97_RS00120	COG1335	isochorismatase
H2N97_RS00125	COG0590	tRNA wobble adenosine to inosine editing
H2N97_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H2N97_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H2N97_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
H2N97_RS00195	COG3853	Toxic anion resistance protein (TelA)
H2N97_RS00200	COG1982	Orn Lys Arg decarboxylase major
H2N97_RS00210	COG3870	Protein conserved in bacteria
H2N97_RS00215	COG1728	Protein conserved in bacteria
H2N97_RS00220	COG0470	DNA polymerase III
H2N97_RS00225	COG1774	PSP1 C-terminal conserved region
H2N97_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H2N97_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H2N97_RS00250	COG2002	toxin-antitoxin pair type II binding
H2N97_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2N97_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2N97_RS00260	COG0084	hydrolase, TatD family'
H2N97_RS00265	COG3583	domain protein
H2N97_RS00265	COG3584	3D domain protein
H2N97_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H2N97_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H2N97_RS00285	COG4466	Protein conserved in bacteria
H2N97_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H2N97_RS00305	COG0251	oxidation-reduction process
H2N97_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H2N97_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H2N97_RS00345	COG2002	toxin-antitoxin pair type II binding
H2N97_RS00350	COG2244	polysaccharide biosynthetic process
H2N97_RS00355	COG3956	TIGRFAM MazG family protein
H2N97_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H2N97_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H2N97_RS00380	COG1098	S1 RNA binding domain
H2N97_RS00395	COG2208	phosphoserine phosphatase activity
H2N97_RS00400	COG2304	oxidoreductase activity
H2N97_RS00405	COG0515	serine threonine protein kinase
H2N97_RS00410	COG0037	tRNA processing
H2N97_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H2N97_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2N97_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H2N97_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H2N97_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
H2N97_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H2N97_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H2N97_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H2N97_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H2N97_RS00475	COG1396	sequence-specific DNA binding
H2N97_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2N97_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H2N97_RS00565	COG4463	regulation of RNA biosynthetic process
H2N97_RS00570	COG3880	PFAM UvrB UvrC protein
H2N97_RS00580	COG0542	response to heat
H2N97_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H2N97_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H2N97_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
H2N97_RS00615	COG1045	serine acetyltransferase
H2N97_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H2N97_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2N97_RS00635	COG3688	RNA-binding protein containing a PIN domain
H2N97_RS00640	COG1595	DNA-templated transcription, initiation
H2N97_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H2N97_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
H2N97_RS00680	COG2813	Specifically methylates the guanine in position
H2N97_RS00695	COG1358	cellular component organization or biogenesis
H2N97_RS00720	COG0596	Alpha beta hydrolase
H2N97_RS00830	COG0201	protein transport
H2N97_RS00840	COG0024	Methionine aminopeptidase
H2N97_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H2N97_RS00875	COG1122	ATPase activity
H2N97_RS00880	COG1122	ATPase activity
H2N97_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H2N97_RS00905	COG2226	methyltransferase
H2N97_RS00910	COG2318	DinB family
H2N97_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS00925	COG0489	protein tyrosine kinase activity
H2N97_RS00935	COG2194	sulfuric ester hydrolase activity
H2N97_RS00940	COG0726	polysaccharide deacetylase
H2N97_RS01000	COG0738	Major facilitator superfamily
H2N97_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2N97_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
H2N97_RS01025	COG0385	Bile acid
H2N97_RS01030	COG2819	hydrolase of the alpha beta superfamily
H2N97_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2N97_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2N97_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H2N97_RS01050	COG2207	Transcriptional regulator
H2N97_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H2N97_RS01055	COG3876	Protein conserved in bacteria
H2N97_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
H2N97_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2N97_RS01070	COG1263	PTS System
H2N97_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H2N97_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H2N97_RS01085	COG1683	Conserved Protein
H2N97_RS01115	COG1595	DNA-templated transcription, initiation
H2N97_RS01120	COG5662	AntiSigma factor
H2N97_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H2N97_RS01130	COG4856	YbbR-like protein
H2N97_RS01170	COG1346	cytolysis
H2N97_RS01175	COG1380	Effector of murein hydrolase LrgA
H2N97_RS01180	COG1846	Transcriptional regulator
H2N97_RS01185	COG1113	amino acid transport
H2N97_RS01190	COG1011	Hydrolase
H2N97_RS01195	COG4585	Histidine kinase
H2N97_RS01200	COG2197	response regulator
H2N97_RS01205	COG1131	(ABC) transporter
H2N97_RS01245	COG0531	amino acid
H2N97_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
H2N97_RS01275	COG2271	Major facilitator Superfamily
H2N97_RS01285	COG2368	4-hydroxyphenylacetate
H2N97_RS01295	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS01310	COG0371	Dehydrogenase
H2N97_RS01320	COG1183	phosphatidylcholine synthase activity
H2N97_RS01325	COG0586	Pfam SNARE associated Golgi protein
H2N97_RS01330	COG0688	phosphatidylethanolamine metabolic process
H2N97_RS01345	COG1301	dicarboxylic acid transport
H2N97_RS01350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H2N97_RS01355	COG0833	amino acid
H2N97_RS01360	COG2040	homocysteine
H2N97_RS01365	COG1115	amino acid carrier protein
H2N97_RS01370	COG2066	Belongs to the glutaminase family
H2N97_RS01380	COG0784	Response regulator, receiver
H2N97_RS01385	COG3173	Aminoglycoside phosphotransferase
H2N97_RS01400	COG3773	Cell wall hydrolase
H2N97_RS01405	COG3540	Alkaline phosphatase
H2N97_RS01410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H2N97_RS01415	COG0805	protein transport
H2N97_RS01425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H2N97_RS01430	COG0477	Major facilitator Superfamily
H2N97_RS01435	COG1309	transcriptional regulator
H2N97_RS01440	COG0252	asparaginase activity
H2N97_RS01445	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H2N97_RS01450	COG3012	SEC-C Motif Domain Protein
H2N97_RS01450	COG1405	negative regulation of cell septum assembly
H2N97_RS01455	COG0667	Aldo Keto reductase
H2N97_RS01465	COG1595	DNA-templated transcription, initiation
H2N97_RS01470	COG1595	DNA-templated transcription, initiation
H2N97_RS01475	COG1876	peptidase activity
H2N97_RS01480	COG0457	Tetratricopeptide repeat
H2N97_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS01495	COG0366	Alpha amylase catalytic
H2N97_RS01500	COG0803	Belongs to the bacterial solute-binding protein 9 family
H2N97_RS01505	COG1121	(ABC) transporter
H2N97_RS01510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H2N97_RS01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2N97_RS01520	COG2310	stress, protein
H2N97_RS01525	COG2310	stress, protein
H2N97_RS01530	COG2310	stress, protein
H2N97_RS01535	COG0861	Integral membrane protein TerC family
H2N97_RS01545	COG3853	Toxic anion resistance protein (TelA)
H2N97_RS01550	COG0477	Major facilitator Superfamily
H2N97_RS01555	COG0517	IMP dehydrogenase activity
H2N97_RS01555	COG4175	Glycine betaine
H2N97_RS01560	COG4176	ABC-type proline glycine betaine transport system permease component
H2N97_RS01565	COG2113	Glycine betaine
H2N97_RS01570	COG1473	amidohydrolase
H2N97_RS01575	COG1288	antiporter activity
H2N97_RS01595	COG2814	Major facilitator Superfamily
H2N97_RS01600	COG1846	Transcriptional regulator
H2N97_RS01605	COG1280	lysine exporter protein (LysE YggA)
H2N97_RS01610	COG3403	YqcI/YcgG family
H2N97_RS01615	COG1113	amino acid transport
H2N97_RS01620	COG3665	Urea carboxylase-associated protein
H2N97_RS01635	COG1660	Displays ATPase and GTPase activities
H2N97_RS01645	COG2271	Major facilitator Superfamily
H2N97_RS01650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H2N97_RS01655	COG3458	cephalosporin-C deacetylase activity
H2N97_RS01660	COG3541	Predicted nucleotidyltransferase
H2N97_RS01665	COG0506	proline dehydrogenase activity
H2N97_RS01670	COG1012	belongs to the aldehyde dehydrogenase family
H2N97_RS01675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2N97_RS01680	COG2508	Transcriptional regulator
H2N97_RS01690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H2N97_RS01690	COG1587	Uroporphyrinogen-III synthase
H2N97_RS01695	COG2146	nitrite reductase [NAD(P)H] activity
H2N97_RS01700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2N97_RS01705	COG0243	molybdopterin cofactor binding
H2N97_RS01710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2N97_RS01720	COG0523	cobalamin synthesis protein
H2N97_RS01725	COG1063	alcohol dehydrogenase
H2N97_RS01730	COG1714	RDD family
H2N97_RS01740	COG2723	6-phospho-beta-galactosidase activity
H2N97_RS01750	COG3209	COG3209 Rhs family protein
H2N97_RS01755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H2N97_RS01760	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H2N97_RS01765	COG1733	regulation of RNA biosynthetic process
H2N97_RS01770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS01780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS01785	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H2N97_RS01800	COG2364	Membrane
H2N97_RS01805	COG1126	abc transporter atp-binding protein
H2N97_RS01810	COG0765	amino acid transport
H2N97_RS01815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2N97_RS01820	COG0583	DNA-binding transcription factor activity
H2N97_RS01825	COG0163	prenyltransferase activity
H2N97_RS01830	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H2N97_RS01845	COG3104	oligopeptide transport
H2N97_RS01850	COG5434	Belongs to the glycosyl hydrolase 28 family
H2N97_RS01860	COG0697	spore germination
H2N97_RS01870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H2N97_RS01875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2N97_RS01880	COG0456	acetyltransferase
H2N97_RS01885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2N97_RS01890	COG0765	amino acid transport
H2N97_RS01895	COG1126	abc transporter atp-binding protein
H2N97_RS01900	COG1473	amidohydrolase
H2N97_RS01905	COG2079	MmgE PrpD family protein
H2N97_RS01910	COG1136	(ABC) transporter
H2N97_RS01915	COG0577	efflux transmembrane transporter activity
H2N97_RS01920	COG0745	RESPONSE REGULATOR receiver
H2N97_RS01925	COG5002	protein histidine kinase activity
H2N97_RS01925	COG3850	Histidine kinase
H2N97_RS01930	COG0457	Tetratricopeptide repeat
H2N97_RS01945	COG0527	aspartate kinase activity
H2N97_RS01950	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2N97_RS01955	COG4605	iron ion homeostasis
H2N97_RS01960	COG4604	ABC transporter, ATP-binding protein
H2N97_RS01965	COG4607	ABC-type enterochelin transport system periplasmic component
H2N97_RS01970	COG2814	Major facilitator Superfamily
H2N97_RS01975	COG1309	transcriptional regulator
H2N97_RS01980	COG0778	Nitroreductase
H2N97_RS01985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H2N97_RS01990	COG0640	Transcriptional regulator
H2N97_RS01995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2N97_RS02000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2N97_RS02005	COG1012	belongs to the aldehyde dehydrogenase family
H2N97_RS02010	COG4975	Glucose uptake
H2N97_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS02020	COG4549	nuclear export factor GLE1
H2N97_RS02030	COG1349	DNA-binding transcription factor activity
H2N97_RS02040	COG2213	PTS system mannitol-specific
H2N97_RS02045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2N97_RS02055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H2N97_RS02065	COG0561	phosphatase activity
H2N97_RS02075	COG1914	H( )-stimulated, divalent metal cation uptake system
H2N97_RS02085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H2N97_RS02090	COG1984	allophanate hydrolase subunit 2
H2N97_RS02095	COG1414	Transcriptional regulator
H2N97_RS02100	COG2755	lipolytic protein G-D-S-L family
H2N97_RS02110	COG2329	Antibiotic biosynthesis monooxygenase
H2N97_RS02115	COG0768	penicillin binding
H2N97_RS02120	COG4989	oxidoreductase activity
H2N97_RS02125	COG3711	transcriptional antiterminator
H2N97_RS02130	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS02140	COG1917	Cupin 2, conserved barrel domain protein
H2N97_RS02145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H2N97_RS02150	COG3871	stress protein (general stress protein 26)
H2N97_RS02160	COG2814	Major facilitator Superfamily
H2N97_RS02165	COG1522	sequence-specific DNA binding
H2N97_RS02170	COG0551	DNA topoisomerase type I activity
H2N97_RS02170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H2N97_RS02175	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H2N97_RS02190	COG1215	transferase activity, transferring glycosyl groups
H2N97_RS02200	COG0531	amino acid
H2N97_RS02205	COG0494	nUDIX hydrolase
H2N97_RS02210	COG0028	Belongs to the TPP enzyme family
H2N97_RS02215	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS02215	COG1388	LysM domain
H2N97_RS02215	COG5632	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS02230	COG0457	Tetratricopeptide repeat
H2N97_RS02250	COG1914	H( )-stimulated, divalent metal cation uptake system
H2N97_RS02260	COG4876	unkown
H2N97_RS02270	COG2076	Multidrug Resistance protein
H2N97_RS02275	COG2217	Heavy metal translocating P-type atpase
H2N97_RS02280	COG3729	General stress protein
H2N97_RS02285	COG0662	Cupin 2, conserved barrel domain protein
H2N97_RS02290	COG2329	Antibiotic biosynthesis monooxygenase
H2N97_RS02295	COG3546	catalase activity
H2N97_RS02300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H2N97_RS02305	COG3290	protein histidine kinase activity
H2N97_RS02310	COG4565	transcriptional regulatory protein
H2N97_RS02315	COG1301	dicarboxylic acid transport
H2N97_RS02320	COG0628	permease
H2N97_RS02325	COG1131	(ABC) transporter
H2N97_RS02330	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H2N97_RS02340	COG1960	acyl-CoA dehydrogenase activity
H2N97_RS02355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H2N97_RS02360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H2N97_RS02370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H2N97_RS02375	COG0513	Belongs to the DEAD box helicase family
H2N97_RS02380	COG3402	PFAM membrane-flanked domain
H2N97_RS02385	COG3428	Bacterial PH domain
H2N97_RS02390	COG0705	Rhomboid family
H2N97_RS02400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H2N97_RS02405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H2N97_RS02410	COG0864	Transcriptional regulator
H2N97_RS02415	COG2337	Toxic component of a toxin-antitoxin (TA) module
H2N97_RS02420	COG1366	Belongs to the anti-sigma-factor antagonist family
H2N97_RS02425	COG1366	Belongs to the anti-sigma-factor antagonist family
H2N97_RS02430	COG2172	sigma factor antagonist activity
H2N97_RS02435	COG2208	phosphoserine phosphatase activity
H2N97_RS02440	COG1366	Belongs to the anti-sigma-factor antagonist family
H2N97_RS02450	COG1191	sigma factor activity
H2N97_RS02455	COG2208	phosphoserine phosphatase activity
H2N97_RS02460	COG2183	response to ionizing radiation
H2N97_RS02510	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2N97_RS02515	COG0457	Tetratricopeptide repeat
H2N97_RS02520	COG0477	Major facilitator Superfamily
H2N97_RS02530	COG2030	dehydratase
H2N97_RS02545	COG1959	2 iron, 2 sulfur cluster binding
H2N97_RS02550	COG2910	NAD(P)H-binding
H2N97_RS02560	COG1309	transcriptional regulator
H2N97_RS02565	COG3239	Fatty acid desaturase
H2N97_RS02575	COG1278	Cold shock
H2N97_RS02580	COG1329	Transcriptional regulator
H2N97_RS02585	COG1794	racemase activity, acting on amino acids and derivatives
H2N97_RS02600	COG3621	Patatin-like phospholipase
H2N97_RS02610	COG0662	Cupin 2, conserved barrel domain protein
H2N97_RS02625	COG0277	FAD linked oxidase domain protein
H2N97_RS02650	COG0662	Cupin 2, conserved barrel domain protein
H2N97_RS02655	COG2318	DinB family
H2N97_RS02660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2N97_RS02685	COG1064	alcohol dehydrogenase
H2N97_RS02690	COG0789	Transcriptional regulator
H2N97_RS02700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2N97_RS02715	COG2814	Major facilitator Superfamily
H2N97_RS02720	COG1309	transcriptional regulator
H2N97_RS02725	COG5577	PFAM Coat F domain
H2N97_RS02735	COG1063	alcohol dehydrogenase
H2N97_RS02740	COG5577	PFAM Coat F domain
H2N97_RS02750	COG4585	Histidine kinase
H2N97_RS02755	COG2197	response regulator
H2N97_RS02760	COG2409	Drug exporters of the RND superfamily
H2N97_RS02765	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H2N97_RS02775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H2N97_RS02780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H2N97_RS02790	COG2814	Major facilitator Superfamily
H2N97_RS02795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H2N97_RS02805	COG0730	response to heat
H2N97_RS02810	COG0456	acetyltransferase
H2N97_RS02815	COG0789	Transcriptional regulator
H2N97_RS02815	COG4978	Transcriptional regulator
H2N97_RS02820	COG0697	spore germination
H2N97_RS02825	COG1051	belongs to the nudix hydrolase family
H2N97_RS02830	COG2226	methyltransferase
H2N97_RS02845	COG1802	Transcriptional regulator
H2N97_RS02850	COG1819	glycosyl
H2N97_RS02865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2N97_RS02875	COG1388	LysM domain
H2N97_RS02880	COG2814	Major facilitator Superfamily
H2N97_RS02885	COG2188	Transcriptional regulator
H2N97_RS02890	COG2186	Transcriptional regulator
H2N97_RS02895	COG2807	transmembrane transport
H2N97_RS02900	COG2076	Multidrug Resistance protein
H2N97_RS02905	COG2076	Multidrug Resistance protein
H2N97_RS02910	COG1309	transcriptional regulator
H2N97_RS02915	COG0531	amino acid
H2N97_RS02925	COG3832	glyoxalase III activity
H2N97_RS02930	COG0604	alcohol dehydrogenase
H2N97_RS02935	COG2814	Major facilitator Superfamily
H2N97_RS02975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H2N97_RS02980	COG0802	atpase or kinase
H2N97_RS02985	COG1214	PFAM Peptidase M22, glycoprotease
H2N97_RS02990	COG0456	acetyltransferase
H2N97_RS02995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H2N97_RS03000	COG0488	(ABC) transporter
H2N97_RS03015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H2N97_RS03020	COG0805	protein transport
H2N97_RS03030	COG1266	CAAX protease self-immunity
H2N97_RS03045	COG0156	8-amino-7-oxononanoate synthase activity
H2N97_RS03085	COG2814	Major facilitator Superfamily
H2N97_RS03090	COG0457	Tetratricopeptide repeat
H2N97_RS03095	COG1063	alcohol dehydrogenase
H2N97_RS03100	COG2211	Major facilitator Superfamily
H2N97_RS03105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H2N97_RS03115	COG1842	Phage shock protein A
H2N97_RS03120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H2N97_RS03125	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H2N97_RS03130	COG4260	virion core protein, lumpy skin disease virus
H2N97_RS03135	COG2755	lipolytic protein G-D-S-L family
H2N97_RS03135	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H2N97_RS03145	COG1595	DNA-templated transcription, initiation
H2N97_RS03150	COG1063	alcohol dehydrogenase
H2N97_RS03155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H2N97_RS03160	COG0823	Involved in the tonB-independent uptake of proteins
H2N97_RS03175	COG2132	Multicopper oxidase
H2N97_RS03180	COG1113	amino acid transport
H2N97_RS03185	COG0714	Associated with various cellular activities
H2N97_RS03195	COG1305	Transglutaminase-like
H2N97_RS03220	COG2252	PERMEase
H2N97_RS03225	COG3064	Membrane
H2N97_RS03245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H2N97_RS03250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H2N97_RS03255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H2N97_RS03260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H2N97_RS03265	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H2N97_RS03280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H2N97_RS03290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H2N97_RS03295	COG0138	bifunctional purine biosynthesis protein purh
H2N97_RS03300	COG0151	Belongs to the GarS family
H2N97_RS03310	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H2N97_RS03315	COG1470	cell adhesion involved in biofilm formation
H2N97_RS03320	COG4496	protein, YerC YecD
H2N97_RS03325	COG0069	glutamate synthase activity
H2N97_RS03335	COG0210	DNA helicase
H2N97_RS03345	COG4851	CamS sex pheromone cAM373 precursor
H2N97_RS03350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H2N97_RS03355	COG1285	pathogenesis
H2N97_RS03360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2N97_RS03380	COG1309	transcriptional regulator
H2N97_RS03385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2N97_RS03390	COG1597	lipid kinase activity
H2N97_RS03395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H2N97_RS03400	COG1136	(ABC) transporter
H2N97_RS03410	COG1131	(ABC) transporter
H2N97_RS03450	COG5444	nuclease activity
H2N97_RS03480	COG3546	catalase activity
H2N97_RS03485	COG0454	-acetyltransferase
H2N97_RS03495	COG2323	membrane
H2N97_RS03500	COG2329	Antibiotic biosynthesis monooxygenase
H2N97_RS03505	COG0346	lactoylglutathione lyase activity
H2N97_RS03510	COG1366	Belongs to the anti-sigma-factor antagonist family
H2N97_RS03515	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H2N97_RS03520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H2N97_RS03525	COG4208	sulfate ABC transporter
H2N97_RS03535	COG5583	Uncharacterized small protein (DUF2292)
H2N97_RS03540	COG0196	riboflavin kinase activity
H2N97_RS03545	COG0670	Belongs to the BI1 family
H2N97_RS03550	COG1846	Transcriptional regulator
H2N97_RS03555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2N97_RS03565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H2N97_RS03565	COG2124	cytochrome p450
H2N97_RS03580	COG1131	(ABC) transporter
H2N97_RS03590	COG1368	sulfuric ester hydrolase activity
H2N97_RS03595	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H2N97_RS03600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H2N97_RS03605	COG1442	glycosyl transferase family 8
H2N97_RS03615	COG1442	glycosyl transferase family 8
H2N97_RS03620	COG2223	nitrite transmembrane transporter activity
H2N97_RS03625	COG0531	amino acid
H2N97_RS03630	COG1012	belongs to the aldehyde dehydrogenase family
H2N97_RS03635	COG0840	transmembrane signaling receptor activity
H2N97_RS03645	COG0463	Glycosyl transferase, family 2
H2N97_RS03650	COG0488	(ABC) transporter
H2N97_RS03655	COG0789	Transcriptional regulator
H2N97_RS03660	COG2814	Major facilitator Superfamily
H2N97_RS03665	COG0488	(ABC) transporter
H2N97_RS03670	COG0513	Belongs to the DEAD box helicase family
H2N97_RS03680	COG2130	NADP-dependent
H2N97_RS03695	COG3866	Pectate lyase
H2N97_RS03700	COG0471	metal ion transport
H2N97_RS03715	COG3290	protein histidine kinase activity
H2N97_RS03720	COG4565	transcriptional regulatory protein
H2N97_RS03725	COG3181	Tripartite tricarboxylate transporter family receptor
H2N97_RS03730	COG2851	Citrate transporter
H2N97_RS03735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2N97_RS03740	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H2N97_RS03750	COG2258	MOSC domain
H2N97_RS03770	COG0024	Methionine aminopeptidase
H2N97_RS03775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H2N97_RS03775	COG1263	PTS System
H2N97_RS03785	COG1368	sulfuric ester hydrolase activity
H2N97_RS03795	COG0071	Belongs to the small heat shock protein (HSP20) family
H2N97_RS03810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H2N97_RS03810	COG1263	PTS System
H2N97_RS03815	COG0366	Alpha amylase catalytic
H2N97_RS03820	COG2188	Transcriptional regulator
H2N97_RS03825	COG0778	Nitroreductase
H2N97_RS03840	COG0737	Belongs to the 5'-nucleotidase family
H2N97_RS03845	COG0693	protein deglycase activity
H2N97_RS03850	COG1609	Transcriptional regulator
H2N97_RS03865	COG2814	Major facilitator Superfamily
H2N97_RS03875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H2N97_RS03880	COG4980	gas vesicle protein
H2N97_RS03885	COG1295	ribonuclease BN
H2N97_RS03895	COG0477	Major facilitator Superfamily
H2N97_RS03900	COG0387	Pfam Sodium calcium exchanger
H2N97_RS03910	COG0668	transmembrane transport
H2N97_RS03915	COG0535	radical SAM domain protein
H2N97_RS03925	COG0726	polysaccharide deacetylase
H2N97_RS03930	COG2084	Dehydrogenase
H2N97_RS03940	COG0598	Magnesium transport protein CorA
H2N97_RS03950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H2N97_RS03965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2N97_RS03970	COG4637	Psort location Cytoplasmic, score
H2N97_RS03975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H2N97_RS03980	COG0022	dehydrogenase e1 component
H2N97_RS03985	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2N97_RS03990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2N97_RS03995	COG3284	Transcriptional regulator
H2N97_RS04005	COG1486	melibiose metabolic process
H2N97_RS04010	COG1737	Transcriptional regulator
H2N97_RS04015	COG1263	PTS System
H2N97_RS04015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H2N97_RS04020	COG1132	(ABC) transporter
H2N97_RS04025	COG1132	(ABC) transporter
H2N97_RS04030	COG2259	Doxx family
H2N97_RS04035	COG2514	catechol 2,3-dioxygenase activity
H2N97_RS04045	COG1695	Transcriptional regulator
H2N97_RS04050	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2N97_RS04055	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
H2N97_RS04060	COG0574	Belongs to the PEP-utilizing enzyme family
H2N97_RS04060	COG3848	Pyruvate phosphate dikinase
H2N97_RS04065	COG2732	(Barnase) inhibitor
H2N97_RS04070	COG2318	DinB family
H2N97_RS04075	COG2814	Major facilitator Superfamily
H2N97_RS04080	COG1846	Transcriptional regulator
H2N97_RS04085	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H2N97_RS04085	COG0392	lysyltransferase activity
H2N97_RS04090	COG0384	phenazine biosynthesis protein PhzF
H2N97_RS04095	COG0778	Nitroreductase
H2N97_RS04110	COG1090	epimerase
H2N97_RS04125	COG2814	Major facilitator Superfamily
H2N97_RS04135	COG3591	Belongs to the peptidase S1B family
H2N97_RS04150	COG3103	Sh3 type 3 domain protein
H2N97_RS04155	COG5658	integral membrane protein
H2N97_RS04160	COG0596	Alpha beta hydrolase
H2N97_RS04165	COG0463	Glycosyl transferase, family 2
H2N97_RS04170	COG4485	Bacterial membrane protein, YfhO
H2N97_RS04175	COG1988	membrane-bound metal-dependent
H2N97_RS04180	COG1194	a g-specific adenine glycosylase
H2N97_RS04190	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS04210	COG1132	(ABC) transporter
H2N97_RS04215	COG4129	membrane
H2N97_RS04225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H2N97_RS04230	COG0735	belongs to the Fur family
H2N97_RS04370	COG5577	PFAM Coat F domain
H2N97_RS04375	COG3340	Belongs to the peptidase S51 family
H2N97_RS04395	COG0747	negative chemotaxis
H2N97_RS04400	COG0601	transmembrane transport
H2N97_RS04405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H2N97_RS04410	COG0444	Belongs to the ABC transporter superfamily
H2N97_RS04415	COG4608	Belongs to the ABC transporter superfamily
H2N97_RS04420	COG0753	catalase activity
H2N97_RS04430	COG1116	anion transmembrane transporter activity
H2N97_RS04435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2N97_RS04440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2N97_RS04460	COG1476	TRANSCRIPTIONal
H2N97_RS04470	COG3382	B3 4 domain protein
H2N97_RS04475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H2N97_RS04485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H2N97_RS04490	COG0789	Transcriptional regulator
H2N97_RS04495	COG1664	Polymer-forming cytoskeletal
H2N97_RS04500	COG1664	Polymer-forming cytoskeletal
H2N97_RS04505	COG2766	serine protein kinase
H2N97_RS04515	COG1846	Transcriptional regulator
H2N97_RS04520	COG1566	PFAM secretion protein HlyD family protein
H2N97_RS04525	COG2814	Major facilitator Superfamily
H2N97_RS04530	COG0655	NAD(P)H dehydrogenase (quinone) activity
H2N97_RS04545	COG1725	Transcriptional regulator
H2N97_RS04550	COG1131	(ABC) transporter
H2N97_RS04555	COG1131	(ABC) transporter
H2N97_RS04560	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H2N97_RS04565	COG1278	Cold shock
H2N97_RS04570	COG1464	Belongs to the NlpA lipoprotein family
H2N97_RS04575	COG3706	GGDEF domain
H2N97_RS04580	COG1823	symporter activity
H2N97_RS04600	COG5577	PFAM Coat F domain
H2N97_RS04605	COG1525	nuclease
H2N97_RS04605	COG4085	toxin activity
H2N97_RS04605	COG0737	Belongs to the 5'-nucleotidase family
H2N97_RS04610	COG3764	Sortase (surface protein transpeptidase)
H2N97_RS04615	COG0564	pseudouridine synthase activity
H2N97_RS04625	COG0517	IMP dehydrogenase activity
H2N97_RS04630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H2N97_RS04635	COG3153	acetyltransferase
H2N97_RS04635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2N97_RS04640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H2N97_RS04645	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H2N97_RS04650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H2N97_RS04660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H2N97_RS04665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2N97_RS04670	COG2203	Gaf domain
H2N97_RS04670	COG4585	Histidine kinase
H2N97_RS04675	COG2197	response regulator
H2N97_RS04680	COG0431	NADPH-dependent FMN reductase
H2N97_RS04695	COG1388	LysM domain
H2N97_RS04695	COG0791	NLP P60 protein
H2N97_RS04700	COG1959	2 iron, 2 sulfur cluster binding
H2N97_RS04705	COG0668	transmembrane transport
H2N97_RS04710	COG2719	SpoVR family
H2N97_RS04715	COG1785	Belongs to the alkaline phosphatase family
H2N97_RS04720	COG1388	LysM domain
H2N97_RS04720	COG0791	NLP P60 protein
H2N97_RS04725	COG0583	DNA-binding transcription factor activity
H2N97_RS04730	COG0372	Belongs to the citrate synthase family
H2N97_RS04735	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS04740	COG0531	amino acid
H2N97_RS04745	COG0733	neurotransmitter:sodium symporter activity
H2N97_RS04760	COG1595	DNA-templated transcription, initiation
H2N97_RS04765	COG0204	Acyl-transferase
H2N97_RS04770	COG1253	flavin adenine dinucleotide binding
H2N97_RS04775	COG0789	Transcriptional regulator
H2N97_RS04785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H2N97_RS04790	COG1253	flavin adenine dinucleotide binding
H2N97_RS04795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H2N97_RS04800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H2N97_RS04805	COG0584	glycerophosphoryl diester phosphodiesterase
H2N97_RS04815	COG0668	transmembrane transport
H2N97_RS04820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H2N97_RS04825	COG0726	polysaccharide deacetylase
H2N97_RS04830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H2N97_RS04835	COG3226	Transcriptional regulator
H2N97_RS04845	COG0589	response to stress
H2N97_RS04850	COG1132	(ABC) transporter
H2N97_RS04855	COG1132	(ABC) transporter
H2N97_RS04860	COG0702	epimerase
H2N97_RS04875	COG0189	ligase activity
H2N97_RS04880	COG0189	ligase activity
H2N97_RS04895	COG4335	DNA alkylation repair
H2N97_RS04900	COG0561	phosphatase activity
H2N97_RS04905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H2N97_RS04915	COG0475	glutathione-regulated potassium exporter activity
H2N97_RS04920	COG0490	domain, Protein
H2N97_RS04930	COG1024	Enoyl-CoA hydratase
H2N97_RS04940	COG4152	abc transporter atp-binding protein
H2N97_RS04945	COG1668	transmembrane transport
H2N97_RS04950	COG0420	3'-5' exonuclease activity
H2N97_RS04955	COG4717	serine-type aminopeptidase activity
H2N97_RS04970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2N97_RS05005	COG4980	gas vesicle protein
H2N97_RS05020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H2N97_RS05025	COG0537	adenosine 5'-monophosphoramidase activity
H2N97_RS05030	COG1131	(ABC) transporter
H2N97_RS05035	COG4473	ABC transporter
H2N97_RS05045	COG1473	amidohydrolase
H2N97_RS05050	COG3069	C4-dicarboxylate transmembrane transporter activity
H2N97_RS05055	COG2329	Antibiotic biosynthesis monooxygenase
H2N97_RS05060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H2N97_RS05080	COG1309	transcriptional regulator
H2N97_RS05085	COG1511	domain protein
H2N97_RS05090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H2N97_RS05100	COG1363	Peptidase, m42
H2N97_RS05105	COG1301	dicarboxylic acid transport
H2N97_RS05115	COG1234	tRNA 3'-trailer cleavage
H2N97_RS05120	COG0095	Lipoate-protein ligase
H2N97_RS05125	COG0702	epimerase
H2N97_RS05130	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS05140	COG0501	Belongs to the peptidase M48B family
H2N97_RS05145	COG1404	Belongs to the peptidase S8 family
H2N97_RS05155	COG0406	alpha-ribazole phosphatase activity
H2N97_RS05160	COG0183	Belongs to the thiolase family
H2N97_RS05165	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS05170	COG1268	BioY protein
H2N97_RS05175	COG0840	transmembrane signaling receptor activity
H2N97_RS05180	COG0723	plastoquinol--plastocyanin reductase activity
H2N97_RS05180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2N97_RS05185	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS05195	COG4903	ComK protein
H2N97_RS05205	COG5646	InterPro IPR014922
H2N97_RS05230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2N97_RS05245	COG0398	Pfam SNARE associated Golgi protein
H2N97_RS05250	COG0681	Belongs to the peptidase S26 family
H2N97_RS05255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2N97_RS05260	COG1846	Transcriptional regulator
H2N97_RS05265	COG3180	Ammonia monooxygenase
H2N97_RS05270	COG2814	Major facilitator Superfamily
H2N97_RS05280	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H2N97_RS05285	COG2323	membrane
H2N97_RS05300	COG0420	3'-5' exonuclease activity
H2N97_RS05305	COG0419	ATPase involved in DNA repair
H2N97_RS05310	COG1403	HNH endonuclease
H2N97_RS05350	COG0179	Fumarylacetoacetate (FAA) hydrolase
H2N97_RS05365	COG0367	asparagine synthase
H2N97_RS05370	COG1562	ergosterol biosynthetic process
H2N97_RS05375	COG0534	Mate efflux family protein
H2N97_RS05380	COG1917	Cupin 2, conserved barrel domain protein
H2N97_RS05380	COG2207	Transcriptional regulator
H2N97_RS05385	COG1609	Transcriptional regulator
H2N97_RS05390	COG0673	inositol 2-dehydrogenase activity
H2N97_RS05395	COG2318	DinB family
H2N97_RS05400	COG1279	arginine transmembrane transporter activity
H2N97_RS05405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2N97_RS05410	COG1357	PFAM Pentapeptide repeats (8 copies)
H2N97_RS05415	COG2153	protein acetylation
H2N97_RS05420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H2N97_RS05420	COG0646	methionine synthase
H2N97_RS05430	COG2996	Protein conserved in bacteria
H2N97_RS05440	COG0840	transmembrane signaling receptor activity
H2N97_RS05445	COG2124	cytochrome p450
H2N97_RS05455	COG1307	EDD domain protein, DegV family
H2N97_RS05460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H2N97_RS05480	COG0561	phosphatase activity
H2N97_RS05485	COG1073	alpha beta
H2N97_RS05490	COG2151	metal-sulfur cluster biosynthetic enzyme
H2N97_RS05500	COG0277	FAD linked oxidase domain protein
H2N97_RS05505	COG2271	Major facilitator Superfamily
H2N97_RS05515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H2N97_RS05525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H2N97_RS05530	COG0505	Belongs to the CarA family
H2N97_RS05535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H2N97_RS05540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H2N97_RS05555	COG2267	carboxylic ester hydrolase activity
H2N97_RS05565	COG1744	ABC transporter substrate-binding protein PnrA-like
H2N97_RS05580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H2N97_RS05585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H2N97_RS05590	COG5504	Zn-dependent protease
H2N97_RS05595	COG0444	Belongs to the ABC transporter superfamily
H2N97_RS05600	COG4608	Belongs to the ABC transporter superfamily
H2N97_RS05610	COG0601	transmembrane transport
H2N97_RS05615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H2N97_RS05625	COG0180	Tryptophanyl-tRNA synthetase
H2N97_RS05630	COG4166	transmembrane transport
H2N97_RS05635	COG0601	transmembrane transport
H2N97_RS05640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H2N97_RS05645	COG0444	Belongs to the ABC transporter superfamily
H2N97_RS05650	COG4608	Belongs to the ABC transporter superfamily
H2N97_RS05660	COG0456	acetyltransferase
H2N97_RS05665	COG1393	Belongs to the ArsC family
H2N97_RS05670	COG0861	Integral membrane protein TerC family
H2N97_RS05675	COG4862	establishment of competence for transformation
H2N97_RS05680	COG4469	Competence protein
H2N97_RS05685	COG1164	Oligoendopeptidase f
H2N97_RS05700	COG2346	COG2346, Truncated hemoglobins
H2N97_RS05705	COG0741	lytic transglycosylase activity
H2N97_RS05710	COG4116	CYTH
H2N97_RS05720	COG2357	RelA SpoT domain protein
H2N97_RS05725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H2N97_RS05730	COG0564	pseudouridine synthase activity
H2N97_RS05740	COG0475	glutathione-regulated potassium exporter activity
H2N97_RS05740	COG0569	domain protein
H2N97_RS05745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H2N97_RS05750	COG0352	thiamine-phosphate diphosphorylase activity
H2N97_RS05755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2N97_RS05760	COG2104	thiamine diphosphate biosynthetic process
H2N97_RS05770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H2N97_RS05775	COG0351	phosphomethylpyrimidine kinase
H2N97_RS05780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H2N97_RS05835	COG0210	DNA helicase
H2N97_RS05855	COG1131	(ABC) transporter
H2N97_RS05865	COG2153	protein acetylation
H2N97_RS05875	COG2382	esterase
H2N97_RS05880	COG0626	cystathionine gamma-synthase activity
H2N97_RS05885	COG0626	cystathionine gamma-synthase activity
H2N97_RS05900	COG2856	Zn peptidase
H2N97_RS05910	COG1396	sequence-specific DNA binding
H2N97_RS05960	COG3935	DnaD domain protein
H2N97_RS05965	COG1484	DNA-dependent DNA replication
H2N97_RS06010	COG1595	DNA-templated transcription, initiation
H2N97_RS06025	COG3591	Belongs to the peptidase S1B family
H2N97_RS06030	COG5484	DNA packaging
H2N97_RS06140	COG4824	toxin secretion phage lysis holin
H2N97_RS06145	COG5632	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS06145	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS06145	COG1388	LysM domain
H2N97_RS06155	COG5444	nuclease activity
H2N97_RS06210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H2N97_RS06210	COG2070	2-Nitropropane dioxygenase
H2N97_RS06215	COG3425	synthase
H2N97_RS06240	COG4221	oxidoreductase activity
H2N97_RS06240	COG3321	synthase
H2N97_RS06240	COG0300	oxidoreductase activity
H2N97_RS06240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS06245	COG3321	synthase
H2N97_RS06245	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS06245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS06245	COG4221	oxidoreductase activity
H2N97_RS06250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS06250	COG0300	oxidoreductase activity
H2N97_RS06250	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS06250	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS06250	COG3321	synthase
H2N97_RS06255	COG3321	synthase
H2N97_RS06255	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS06255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS06255	COG4221	oxidoreductase activity
H2N97_RS06285	COG0250	Participates in transcription elongation, termination and antitermination
H2N97_RS06320	COG0537	adenosine 5'-monophosphoramidase activity
H2N97_RS06330	COG5484	DNA packaging
H2N97_RS06335	COG2367	Beta-lactamase
H2N97_RS06340	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H2N97_RS06345	COG0477	Major facilitator Superfamily
H2N97_RS06350	COG1846	Transcriptional regulator
H2N97_RS06360	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H2N97_RS06365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H2N97_RS06370	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H2N97_RS06375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H2N97_RS06375	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H2N97_RS06380	COG1447	Phosphotransferase system cellobiose-specific component IIA
H2N97_RS06390	COG1349	DNA-binding transcription factor activity
H2N97_RS06410	COG1285	pathogenesis
H2N97_RS06425	COG2205	protein histidine kinase activity
H2N97_RS06435	COG3383	formate dehydrogenase (NAD+) activity
H2N97_RS06440	COG2427	Protein of unknown function (DUF1641)
H2N97_RS06445	COG2124	cytochrome p450
H2N97_RS06450	COG1819	glycosyl
H2N97_RS06460	COG1587	Uroporphyrinogen-III synthase
H2N97_RS06465	COG0390	transport system, permease component
H2N97_RS06470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H2N97_RS06475	COG0697	spore germination
H2N97_RS06480	COG4297	protein containing double-stranded beta helix domain
H2N97_RS06490	COG1252	NADH dehydrogenase
H2N97_RS06505	COG1609	Transcriptional regulator
H2N97_RS06510	COG0246	Mannitol dehydrogenase
H2N97_RS06515	COG2721	sulfolactate sulfo-lyase activity
H2N97_RS06520	COG0745	RESPONSE REGULATOR receiver
H2N97_RS06525	COG2205	protein histidine kinase activity
H2N97_RS06525	COG2770	Histidine kinase
H2N97_RS06545	COG4585	Histidine kinase
H2N97_RS06550	COG2197	response regulator
H2N97_RS06585	COG0730	response to heat
H2N97_RS06590	COG2318	DinB family
H2N97_RS06595	COG0457	Tetratricopeptide repeat
H2N97_RS06605	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS06605	COG5632	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS06605	COG1388	LysM domain
H2N97_RS06615	COG4195	phage-related replication protein
H2N97_RS06620	COG2856	Zn peptidase
H2N97_RS06625	COG1396	sequence-specific DNA binding
H2N97_RS06635	COG1522	sequence-specific DNA binding
H2N97_RS06640	COG1484	DNA-dependent DNA replication
H2N97_RS06660	COG1595	DNA-templated transcription, initiation
H2N97_RS06665	COG4193	domain, Protein
H2N97_RS06700	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS06700	COG5632	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS06715	COG0306	phosphate transporter
H2N97_RS06720	COG1392	Phosphate transport regulator
H2N97_RS06725	COG0531	amino acid
H2N97_RS06730	COG0346	lactoylglutathione lyase activity
H2N97_RS06735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H2N97_RS06740	COG0463	Glycosyl transferase, family 2
H2N97_RS06750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2N97_RS06755	COG0477	Major facilitator Superfamily
H2N97_RS06760	COG2362	D-Aminopeptidase
H2N97_RS06765	COG0601	transmembrane transport
H2N97_RS06770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H2N97_RS06775	COG0444	Belongs to the ABC transporter superfamily
H2N97_RS06780	COG4166	transmembrane transport
H2N97_RS06785	COG1619	proteins homologs of microcin C7 resistance protein MccF
H2N97_RS06790	COG4948	Mandelate Racemase Muconate Lactonizing
H2N97_RS06795	COG0791	NLP P60 protein
H2N97_RS06800	COG4608	Belongs to the ABC transporter superfamily
H2N97_RS06805	COG2706	6-phosphogluconolactonase activity
H2N97_RS06810	COG1834	amidinotransferase
H2N97_RS06815	COG1607	acyl-coa hydrolase
H2N97_RS06820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H2N97_RS06825	COG2076	Multidrug Resistance protein
H2N97_RS06830	COG2076	Multidrug Resistance protein
H2N97_RS06835	COG0788	formyltetrahydrofolate deformylase activity
H2N97_RS06840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H2N97_RS06850	COG1764	response to oxidative stress
H2N97_RS06855	COG1846	Transcriptional regulator
H2N97_RS06860	COG1764	response to oxidative stress
H2N97_RS06875	COG0457	Tetratricopeptide repeat
H2N97_RS06875	COG0463	Glycosyl transferase, family 2
H2N97_RS06885	COG2814	Major facilitator Superfamily
H2N97_RS06890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2N97_RS06900	COG1404	Belongs to the peptidase S8 family
H2N97_RS06905	COG1366	Belongs to the anti-sigma-factor antagonist family
H2N97_RS06910	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H2N97_RS06915	COG1122	ATPase activity
H2N97_RS06920	COG4721	ABC-type cobalt transport system, permease component
H2N97_RS06925	COG3858	chitin binding
H2N97_RS06925	COG1388	LysM domain
H2N97_RS06935	COG2239	Acts as a magnesium transporter
H2N97_RS06940	COG0789	Transcriptional regulator
H2N97_RS06955	COG1846	Transcriptional regulator
H2N97_RS06960	COG0726	polysaccharide deacetylase
H2N97_RS06965	COG3285	dna ligase
H2N97_RS06965	COG1793	dna ligase
H2N97_RS06970	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H2N97_RS06975	COG0586	Pfam SNARE associated Golgi protein
H2N97_RS06980	COG0861	Integral membrane protein TerC family
H2N97_RS06985	COG1191	sigma factor activity
H2N97_RS07010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H2N97_RS07015	COG2323	membrane
H2N97_RS07025	COG3594	Acyltransferase
H2N97_RS07030	COG5002	protein histidine kinase activity
H2N97_RS07035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2N97_RS07050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2N97_RS07055	COG0436	Aminotransferase
H2N97_RS07085	COG3852	Histidine kinase
H2N97_RS07090	COG1846	Transcriptional regulator
H2N97_RS07095	COG1360	Flagellar Motor Protein
H2N97_RS07100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H2N97_RS07105	COG0542	response to heat
H2N97_RS07110	COG3949	Membrane
H2N97_RS07125	COG0720	synthase
H2N97_RS07130	COG0602	queuosine metabolic process
H2N97_RS07135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H2N97_RS07140	COG1733	regulation of RNA biosynthetic process
H2N97_RS07145	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS07165	COG4873	Protein conserved in bacteria
H2N97_RS07175	COG3773	Cell wall hydrolase
H2N97_RS07180	COG2244	polysaccharide biosynthetic process
H2N97_RS07185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H2N97_RS07190	COG2217	Heavy metal translocating P-type atpase
H2N97_RS07195	COG0006	proline dipeptidase activity
H2N97_RS07200	COG1609	Transcriptional regulator
H2N97_RS07205	COG3711	transcriptional antiterminator
H2N97_RS07210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H2N97_RS07210	COG1263	PTS System
H2N97_RS07210	COG2190	(PTS) system
H2N97_RS07215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2N97_RS07220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H2N97_RS07230	COG1533	DNA photolyase activity
H2N97_RS07235	COG0840	transmembrane signaling receptor activity
H2N97_RS07240	COG2084	Dehydrogenase
H2N97_RS07245	COG2340	Cysteine-rich secretory protein family
H2N97_RS07250	COG0768	penicillin binding
H2N97_RS07255	COG4191	Histidine kinase
H2N97_RS07260	COG0436	Aminotransferase
H2N97_RS07270	COG0784	Response regulator, receiver
H2N97_RS07270	COG0835	chemotaxis
H2N97_RS07280	COG2814	Major facilitator Superfamily
H2N97_RS07285	COG1376	ErfK ybiS ycfS ynhG family protein
H2N97_RS07290	COG1408	metallophosphoesterase
H2N97_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS07305	COG2200	EAL domain
H2N97_RS07310	COG4703	Protein of unknown function (DUF1797)
H2N97_RS07315	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H2N97_RS07325	COG0517	IMP dehydrogenase activity
H2N97_RS07330	COG0583	DNA-binding transcription factor activity
H2N97_RS07335	COG0716	FMN binding
H2N97_RS07345	COG0716	FMN binding
H2N97_RS07365	COG0668	transmembrane transport
H2N97_RS07370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H2N97_RS07390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H2N97_RS07395	COG0303	'Molybdopterin
H2N97_RS07400	COG1763	Mo-molybdopterin cofactor biosynthetic process
H2N97_RS07405	COG0314	molybdopterin synthase activity
H2N97_RS07410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H2N97_RS07420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2N97_RS07425	COG1136	(ABC) transporter
H2N97_RS07430	COG0577	efflux transmembrane transporter activity
H2N97_RS07435	COG1349	DNA-binding transcription factor activity
H2N97_RS07440	COG1105	Belongs to the carbohydrate kinase PfkB family
H2N97_RS07445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2N97_RS07445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2N97_RS07445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2N97_RS07450	COG0681	Belongs to the peptidase S26 family
H2N97_RS07460	COG0488	(ABC) transporter
H2N97_RS07465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H2N97_RS07470	COG2309	aminopeptidase activity
H2N97_RS07480	COG1077	Cell shape determining protein MreB Mrl
H2N97_RS07485	COG2002	toxin-antitoxin pair type II binding
H2N97_RS07490	COG3852	Histidine kinase
H2N97_RS07495	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H2N97_RS07495	COG2105	PFAM AIG2 family protein
H2N97_RS07500	COG0569	domain protein
H2N97_RS07510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H2N97_RS07525	COG0242	peptide deformylase activity
H2N97_RS07535	COG0497	DNA recombination
H2N97_RS07545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS07545	COG3321	synthase
H2N97_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS07545	COG4221	oxidoreductase activity
H2N97_RS07550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS07550	COG0300	oxidoreductase activity
H2N97_RS07550	COG4221	oxidoreductase activity
H2N97_RS07550	COG3321	synthase
H2N97_RS07555	COG4221	oxidoreductase activity
H2N97_RS07555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS07555	COG3321	synthase
H2N97_RS07555	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS07560	COG3321	synthase
H2N97_RS07560	COG0300	oxidoreductase activity
H2N97_RS07560	COG4221	oxidoreductase activity
H2N97_RS07560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS07565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS07565	COG3321	synthase
H2N97_RS07565	COG4221	oxidoreductase activity
H2N97_RS07565	COG0300	oxidoreductase activity
H2N97_RS07570	COG0300	oxidoreductase activity
H2N97_RS07570	COG3321	synthase
H2N97_RS07570	COG4221	oxidoreductase activity
H2N97_RS07570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS07575	COG3321	synthase
H2N97_RS07575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS07575	COG4221	oxidoreductase activity
H2N97_RS07575	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS07580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2N97_RS07585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H2N97_RS07590	COG0022	dehydrogenase e1 component
H2N97_RS07595	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2N97_RS07600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2N97_RS07605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H2N97_RS07620	COG1982	Orn Lys Arg decarboxylase major
H2N97_RS07640	COG0483	inositol monophosphate 1-phosphatase activity
H2N97_RS07650	COG3227	Zinc metalloprotease (Elastase)
H2N97_RS07685	COG4896	Protein conserved in bacteria
H2N97_RS07695	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H2N97_RS07700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H2N97_RS07705	COG2066	Belongs to the glutaminase family
H2N97_RS07715	COG0772	Belongs to the SEDS family
H2N97_RS07720	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H2N97_RS07735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H2N97_RS07735	COG2010	Cytochrome c
H2N97_RS07740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H2N97_RS07745	COG1845	cytochrome c oxidase, subunit III
H2N97_RS07750	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H2N97_RS07755	COG3336	cytochrome c oxidase
H2N97_RS07765	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H2N97_RS07770	COG2340	Cysteine-rich secretory protein family
H2N97_RS07785	COG3679	Belongs to the UPF0342 family
H2N97_RS07795	COG0742	ribosomal rna small subunit methyltransferase
H2N97_RS07805	COG3314	Sporulation integral membrane protein YlbJ
H2N97_RS07810	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2N97_RS07815	COG3480	Lon protease (S16) C-terminal proteolytic domain
H2N97_RS07825	COG1399	metal-binding, possibly nucleic acid-binding protein
H2N97_RS07845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H2N97_RS07865	COG4839	cell division protein FtsL
H2N97_RS07875	COG0768	penicillin binding
H2N97_RS07895	COG0772	Belongs to the SEDS family
H2N97_RS07910	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H2N97_RS07915	COG0849	cell division
H2N97_RS07920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H2N97_RS07925	COG4412	M6 family metalloprotease domain protein
H2N97_RS07925	COG1404	Belongs to the peptidase S8 family
H2N97_RS07935	COG1191	sigma factor activity
H2N97_RS07940	COG1191	sigma factor activity
H2N97_RS07945	COG1119	ATPase activity
H2N97_RS07950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H2N97_RS07955	COG1873	PFAM PRC-barrel domain
H2N97_RS07965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H2N97_RS07975	COG0762	integral membrane protein
H2N97_RS07980	COG2302	S4 RNA-binding domain
H2N97_RS07985	COG3599	regulation of cell shape
H2N97_RS07990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H2N97_RS07995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H2N97_RS08005	COG0564	pseudouridine synthase activity
H2N97_RS08015	COG2233	PERMEase
H2N97_RS08025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H2N97_RS08030	COG0505	Belongs to the CarA family
H2N97_RS08035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H2N97_RS08050	COG0284	orotidine-5'-phosphate decarboxylase activity
H2N97_RS08055	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H2N97_RS08065	COG0306	phosphate transporter
H2N97_RS08080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H2N97_RS08085	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
H2N97_RS08090	COG1648	precorrin-2 dehydrogenase activity
H2N97_RS08100	COG1293	RNA-binding protein homologous to eukaryotic snRNP
H2N97_RS08105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H2N97_RS08110	COG1561	YicC-like family, N-terminal region
H2N97_RS08120	COG0194	GDP metabolic process
H2N97_RS08130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H2N97_RS08135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H2N97_RS08140	COG0242	peptide deformylase activity
H2N97_RS08150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H2N97_RS08150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H2N97_RS08160	COG0631	protein serine/threonine phosphatase activity
H2N97_RS08165	COG2815	serine threonine protein kinase
H2N97_RS08165	COG0515	serine threonine protein kinase
H2N97_RS08175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H2N97_RS08180	COG1564	THIamine pyrophosphokinase
H2N97_RS08195	COG1302	Protein conserved in bacteria
H2N97_RS08200	COG1461	Dihydroxyacetone kinase
H2N97_RS08205	COG1760	l-serine dehydratase
H2N97_RS08210	COG1760	l-serine dehydratase
H2N97_RS08215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H2N97_RS08230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H2N97_RS08235	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS08250	COG1196	nuclear chromosome segregation
H2N97_RS08255	COG0552	protein localization to endoplasmic reticulum
H2N97_RS08270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H2N97_RS08280	COG1837	Belongs to the UPF0109 family
H2N97_RS08305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H2N97_RS08320	COG2257	FlhB HrpN YscU SpaS Family
H2N97_RS08330	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H2N97_RS08335	COG0758	DNA mediated transformation
H2N97_RS08340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H2N97_RS08350	COG4974	Belongs to the 'phage' integrase family
H2N97_RS08370	COG1815	bacterial-type flagellum-dependent cell motility
H2N97_RS08375	COG1558	bacterial-type flagellum-dependent cell motility
H2N97_RS08380	COG1677	Flagellar hook-basal body complex protein FliE
H2N97_RS08385	COG1766	The M ring may be actively involved in energy transduction
H2N97_RS08390	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H2N97_RS08395	COG1317	bacterial-type flagellum organization
H2N97_RS08400	COG1157	protein secretion by the type III secretion system
H2N97_RS08405	COG2882	bacterial-type flagellum organization
H2N97_RS08410	COG3334	PFAM MgtE intracellular
H2N97_RS08415	COG3144	bacterial-type flagellum assembly
H2N97_RS08420	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H2N97_RS08425	COG4786	Flagellar basal body rod
H2N97_RS08430	COG1582	Flagellar protein (FlbD)
H2N97_RS08435	COG1580	Controls the rotational direction of flagella during chemotaxis
H2N97_RS08440	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H2N97_RS08445	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H2N97_RS08445	COG1776	CheC inhibitor of MCP methylation
H2N97_RS08450	COG2201	protein-glutamate methylesterase activity
H2N97_RS08455	COG3190	flagellar
H2N97_RS08460	COG1338	Plays a role in the flagellum-specific transport system
H2N97_RS08465	COG1987	bacterial-type flagellum assembly
H2N97_RS08470	COG1684	flagellar biosynthetic protein fliR
H2N97_RS08475	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H2N97_RS08480	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H2N97_RS08485	COG1419	protein localization to endoplasmic reticulum
H2N97_RS08490	COG0455	bacterial-type flagellum organization
H2N97_RS08495	COG2201	protein-glutamate methylesterase activity
H2N97_RS08500	COG0643	Histidine kinase
H2N97_RS08500	COG2198	Histidine kinase
H2N97_RS08505	COG0835	chemotaxis
H2N97_RS08510	COG1776	CheC inhibitor of MCP methylation
H2N97_RS08520	COG1191	sigma factor activity
H2N97_RS08550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H2N97_RS08555	COG4589	Belongs to the CDS family
H2N97_RS08565	COG0750	zinc metalloprotease
H2N97_RS08575	COG2176	DNA-directed DNA polymerase activity
H2N97_RS08585	COG0195	Participates in both transcription termination and antitermination
H2N97_RS08590	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H2N97_RS08595	COG1358	cellular component organization or biogenesis
H2N97_RS08605	COG1550	Protein conserved in bacteria
H2N97_RS08620	COG0196	riboflavin kinase activity
H2N97_RS08635	COG0726	polysaccharide deacetylase
H2N97_RS08640	COG0612	Peptidase, M16
H2N97_RS08645	COG1873	PFAM PRC-barrel domain
H2N97_RS08650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H2N97_RS08655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H2N97_RS08660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H2N97_RS08665	COG0527	aspartate kinase activity
H2N97_RS08675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H2N97_RS08680	COG0740	serine-type endopeptidase activity
H2N97_RS08690	COG4980	gas vesicle protein
H2N97_RS08690	COG1674	ftsk spoiiie
H2N97_RS08695	COG2188	Transcriptional regulator
H2N97_RS08700	COG2814	Major facilitator Superfamily
H2N97_RS08705	COG1846	Transcriptional regulator
H2N97_RS08710	COG2409	Drug exporters of the RND superfamily
H2N97_RS08710	COG1033	growth of symbiont in host cell
H2N97_RS08715	COG0612	Peptidase, M16
H2N97_RS08720	COG0612	Peptidase, M16
H2N97_RS08725	COG0300	oxidoreductase activity
H2N97_RS08740	COG1426	Protein conserved in bacteria
H2N97_RS08745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H2N97_RS08760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2N97_RS08770	COG1692	metallophosphoesterase
H2N97_RS08775	COG2359	stage V sporulation protein S
H2N97_RS08795	COG4550	Control of competence regulator ComK, YlbF/YmcA
H2N97_RS08840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS08845	COG3425	synthase
H2N97_RS08850	COG1024	Enoyl-CoA hydratase
H2N97_RS08855	COG1024	Enoyl-CoA hydratase
H2N97_RS08865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H2N97_RS08865	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H2N97_RS08865	COG3321	synthase
H2N97_RS08865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS08870	COG2124	cytochrome p450
H2N97_RS08875	COG3209	COG3209 Rhs family protein
H2N97_RS08880	COG3619	membrane
H2N97_RS08890	COG1404	Belongs to the peptidase S8 family
H2N97_RS08900	COG4195	phage-related replication protein
H2N97_RS08905	COG1764	response to oxidative stress
H2N97_RS08915	COG2076	Multidrug Resistance protein
H2N97_RS08955	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H2N97_RS08960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H2N97_RS08965	COG4112	unkown
H2N97_RS08970	COG0860	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS08975	COG0464	growth
H2N97_RS08980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H2N97_RS08985	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H2N97_RS08990	COG0789	Transcriptional regulator
H2N97_RS08995	COG0174	glutamine synthetase
H2N97_RS09000	COG0582	viral genome integration into host DNA
H2N97_RS09010	COG1525	nuclease
H2N97_RS09015	COG5444	nuclease activity
H2N97_RS09030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H2N97_RS09055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H2N97_RS09060	COG0457	Tetratricopeptide repeat
H2N97_RS09080	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS09080	COG5632	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS09085	COG5434	Belongs to the glycosyl hydrolase 28 family
H2N97_RS09275	COG0776	regulation of translation
H2N97_RS09320	COG3645	SOS response
H2N97_RS09320	COG3646	Phage regulatory protein
H2N97_RS09355	COG3655	Transcriptional regulator
H2N97_RS09360	COG3655	Transcriptional regulator
H2N97_RS09450	COG0582	viral genome integration into host DNA
H2N97_RS09465	COG3655	Transcriptional regulator
H2N97_RS09575	COG1793	dna ligase
H2N97_RS09580	COG2135	peptidase activity
H2N97_RS09605	COG4195	phage-related replication protein
H2N97_RS09610	COG5434	Belongs to the glycosyl hydrolase 28 family
H2N97_RS09610	COG3420	alginic acid biosynthetic process
H2N97_RS09615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H2N97_RS09655	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H2N97_RS09665	COG3584	3D domain protein
H2N97_RS09685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H2N97_RS09770	COG1780	Probably involved in ribonucleotide reductase function
H2N97_RS09775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H2N97_RS09810	COG0756	dUTP diphosphatase activity
H2N97_RS09835	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H2N97_RS09840	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H2N97_RS09895	COG3331	DNA recombination
H2N97_RS09920	COG2211	Major facilitator Superfamily
H2N97_RS09925	COG3507	Belongs to the glycosyl hydrolase 43 family
H2N97_RS09940	COG1070	Carbohydrate kinase
H2N97_RS09945	COG0574	Belongs to the PEP-utilizing enzyme family
H2N97_RS09945	COG3848	Pyruvate phosphate dikinase
H2N97_RS09970	COG2378	regulation of single-species biofilm formation
H2N97_RS09975	COG2318	DinB family
H2N97_RS09980	COG1064	alcohol dehydrogenase
H2N97_RS10000	COG5444	nuclease activity
H2N97_RS10060	COG3397	chitin binding
H2N97_RS10080	COG5434	Belongs to the glycosyl hydrolase 28 family
H2N97_RS10085	COG0756	dUTP diphosphatase activity
H2N97_RS10090	COG4195	phage-related replication protein
H2N97_RS10125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H2N97_RS10135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H2N97_RS10155	COG0785	Cytochrome C biogenesis protein
H2N97_RS10160	COG2201	protein-glutamate methylesterase activity
H2N97_RS10165	COG4846	Membrane protein involved in cytochrome C biogenesis
H2N97_RS10175	COG0071	Belongs to the small heat shock protein (HSP20) family
H2N97_RS10190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H2N97_RS10195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H2N97_RS10215	COG0824	Thioesterase
H2N97_RS10225	COG4841	protein insertion into membrane
H2N97_RS10235	COG1832	CoA-binding protein
H2N97_RS10240	COG0187	DNA topoisomerase II activity
H2N97_RS10245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H2N97_RS10255	COG1115	amino acid carrier protein
H2N97_RS10265	COG1063	alcohol dehydrogenase
H2N97_RS10270	COG0800	Aldolase
H2N97_RS10275	COG1312	Catalyzes the dehydration of D-mannonate
H2N97_RS10280	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS10285	COG1609	Transcriptional regulator
H2N97_RS10325	COG2205	protein histidine kinase activity
H2N97_RS10330	COG0745	RESPONSE REGULATOR receiver
H2N97_RS10340	COG3507	Belongs to the glycosyl hydrolase 43 family
H2N97_RS10365	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS10370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2N97_RS10375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2N97_RS10380	COG2610	gluconate transmembrane transporter activity
H2N97_RS10385	COG2124	cytochrome p450
H2N97_RS10405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H2N97_RS10415	COG2246	polysaccharide biosynthetic process
H2N97_RS10420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H2N97_RS10425	COG0586	Pfam SNARE associated Golgi protein
H2N97_RS10430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H2N97_RS10435	COG1024	Enoyl-CoA hydratase
H2N97_RS10440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H2N97_RS10445	COG0511	ligase activity, forming carbon-carbon bonds
H2N97_RS10450	COG0439	Biotin carboxylase
H2N97_RS10455	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS10460	COG1960	acyl-CoA dehydrogenase activity
H2N97_RS10465	COG1649	PFAM Uncharacterised BCR, COG1649
H2N97_RS10475	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H2N97_RS10475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS10490	COG2027	D-alanyl-D-alanine carboxypeptidase
H2N97_RS10495	COG2017	converts alpha-aldose to the beta-anomer
H2N97_RS10500	COG0534	Mate efflux family protein
H2N97_RS10515	COG0582	viral genome integration into host DNA
H2N97_RS10520	COG0166	Belongs to the GPI family
H2N97_RS10525	COG0405	Gamma-glutamyltransferase
H2N97_RS10535	COG0640	Transcriptional regulator
H2N97_RS10540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H2N97_RS10550	COG0604	alcohol dehydrogenase
H2N97_RS10560	COG0493	'glutamate synthase
H2N97_RS10565	COG0070	glutamate synthase
H2N97_RS10565	COG0067	glutamate synthase
H2N97_RS10565	COG0069	glutamate synthase activity
H2N97_RS10570	COG0583	DNA-binding transcription factor activity
H2N97_RS10575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H2N97_RS10595	COG0300	oxidoreductase activity
H2N97_RS10600	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H2N97_RS10610	COG2814	Major facilitator Superfamily
H2N97_RS10615	COG1070	Carbohydrate kinase
H2N97_RS10620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H2N97_RS10625	COG0243	molybdopterin cofactor binding
H2N97_RS10655	COG5444	nuclease activity
H2N97_RS10660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2N97_RS10665	COG0662	Cupin 2, conserved barrel domain protein
H2N97_RS10665	COG2207	Transcriptional regulator
H2N97_RS10670	COG1309	transcriptional regulator
H2N97_RS10675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2N97_RS10685	COG0640	Transcriptional regulator
H2N97_RS10690	COG0741	lytic transglycosylase activity
H2N97_RS10695	COG2322	membrane
H2N97_RS10710	COG1619	proteins homologs of microcin C7 resistance protein MccF
H2N97_RS10720	COG3584	3D domain protein
H2N97_RS10720	COG1388	LysM domain
H2N97_RS10725	COG0514	ATP-dependent DNA helicase (RecQ)
H2N97_RS10735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H2N97_RS10740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H2N97_RS10755	COG0071	Belongs to the small heat shock protein (HSP20) family
H2N97_RS10785	COG1012	belongs to the aldehyde dehydrogenase family
H2N97_RS10790	COG1657	PFAM Prenyltransferase squalene oxidase
H2N97_RS10795	COG1657	PFAM Prenyltransferase squalene oxidase
H2N97_RS10800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H2N97_RS10805	COG0733	neurotransmitter:sodium symporter activity
H2N97_RS10810	COG0385	Bile acid
H2N97_RS10815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2N97_RS10820	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2N97_RS10830	COG4548	von Willebrand factor, type A
H2N97_RS10835	COG0714	Associated with various cellular activities
H2N97_RS10840	COG2032	superoxide dismutase activity
H2N97_RS10845	COG1388	LysM domain
H2N97_RS10845	COG0791	NLP P60 protein
H2N97_RS10850	COG1819	glycosyl
H2N97_RS10855	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H2N97_RS10860	COG0534	Mate efflux family protein
H2N97_RS10865	COG1366	Belongs to the anti-sigma-factor antagonist family
H2N97_RS10870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H2N97_RS10875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H2N97_RS10885	COG2962	Rard protein
H2N97_RS10900	COG1942	4-Oxalocrotonate Tautomerase
H2N97_RS10910	COG1733	regulation of RNA biosynthetic process
H2N97_RS10915	COG0778	Nitroreductase
H2N97_RS10920	COG0400	carboxylic ester hydrolase activity
H2N97_RS10925	COG0346	lactoylglutathione lyase activity
H2N97_RS10935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2N97_RS10950	COG2188	Transcriptional regulator
H2N97_RS10955	COG0793	Belongs to the peptidase S41A family
H2N97_RS10955	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS10960	COG2226	methyltransferase
H2N97_RS10970	COG1876	peptidase activity
H2N97_RS10990	COG0671	phosphoesterase, PA-phosphatase related
H2N97_RS11020	COG1509	lysine 2,3-aminomutase activity
H2N97_RS11025	COG0456	acetyltransferase
H2N97_RS11030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H2N97_RS11035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2N97_RS11040	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2N97_RS11045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H2N97_RS11050	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H2N97_RS11060	COG0456	acetyltransferase
H2N97_RS11065	COG0463	Glycosyl transferase, family 2
H2N97_RS11080	COG4641	Protein conserved in bacteria
H2N97_RS11090	COG1086	Polysaccharide biosynthesis protein
H2N97_RS11105	COG1846	Transcriptional regulator
H2N97_RS11110	COG4698	Protein conserved in bacteria
H2N97_RS11115	COG2755	lipolytic protein G-D-S-L family
H2N97_RS11120	COG1999	signal sequence binding
H2N97_RS11130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H2N97_RS11135	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H2N97_RS11140	COG1272	protein, Hemolysin III
H2N97_RS11145	COG0204	Acyl-transferase
H2N97_RS11150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H2N97_RS11165	COG2136	Putative SAM-dependent methyltransferase
H2N97_RS11165	COG2521	methyltransferase
H2N97_RS11180	COG1413	lyase activity
H2N97_RS11185	COG1418	mRNA catabolic process
H2N97_RS11190	COG0386	Belongs to the glutathione peroxidase family
H2N97_RS11200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H2N97_RS11210	COG1278	Cold shock
H2N97_RS11230	COG0328	RNA-DNA hybrid ribonuclease activity
H2N97_RS11235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H2N97_RS11240	COG0328	RNA-DNA hybrid ribonuclease activity
H2N97_RS11250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H2N97_RS11265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H2N97_RS11285	COG1335	isochorismatase
H2N97_RS11290	COG2233	PERMEase
H2N97_RS11300	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H2N97_RS11305	COG1199	ATP-dependent helicase activity
H2N97_RS11320	COG0116	Belongs to the methyltransferase superfamily
H2N97_RS11350	COG3359	exonuclease
H2N97_RS11355	COG1111	helicase
H2N97_RS11355	COG1205	dead DEAH box helicase
H2N97_RS11360	COG2190	(PTS) system
H2N97_RS11365	COG0071	Belongs to the small heat shock protein (HSP20) family
H2N97_RS11405	COG4499	WXG100 protein secretion system (Wss), protein YukC
H2N97_RS11405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H2N97_RS11415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H2N97_RS11420	COG3935	DnaD domain protein
H2N97_RS11430	COG0436	Aminotransferase
H2N97_RS11435	COG5353	protein conserved in bacteria
H2N97_RS11445	COG1199	ATP-dependent helicase activity
H2N97_RS11445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H2N97_RS11475	COG0438	transferase activity, transferring glycosyl groups
H2N97_RS11480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H2N97_RS11495	COG1694	Mazg nucleotide pyrophosphohydrolase
H2N97_RS11500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H2N97_RS11505	COG2140	Oxalate decarboxylase
H2N97_RS11515	COG4347	Protein of unknown function (DUF1405)
H2N97_RS11520	COG2010	Cytochrome c
H2N97_RS11520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H2N97_RS11525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H2N97_RS11530	COG0723	plastoquinol--plastocyanin reductase activity
H2N97_RS11545	COG0457	Tetratricopeptide repeat
H2N97_RS11555	COG0287	Prephenate dehydrogenase
H2N97_RS11590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H2N97_RS11595	COG4401	Chorismate mutase type I
H2N97_RS11610	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H2N97_RS11615	COG0105	UTP biosynthetic process
H2N97_RS11620	COG0142	geranyltranstransferase activity
H2N97_RS11630	COG0142	geranyltranstransferase activity
H2N97_RS11645	COG0776	regulation of translation
H2N97_RS11650	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H2N97_RS11690	COG0539	negative regulation of cytoplasmic translation
H2N97_RS11705	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H2N97_RS11710	COG2959	enzyme of heme biosynthesis
H2N97_RS11715	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS11715	COG3773	Cell wall hydrolase
H2N97_RS11720	COG2339	peptidase activity
H2N97_RS11725	COG0492	ferredoxin-NADP+ reductase activity
H2N97_RS11730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2N97_RS11735	COG4862	establishment of competence for transformation
H2N97_RS11740	COG1408	metallophosphoesterase
H2N97_RS11750	COG1388	LysM domain
H2N97_RS11755	COG1266	CAAX protease self-immunity
H2N97_RS11760	COG0514	ATP-dependent DNA helicase (RecQ)
H2N97_RS11765	COG4955	Helix-turn-helix domain
H2N97_RS11770	COG1141	Ferredoxin
H2N97_RS11775	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H2N97_RS11780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H2N97_RS11790	COG1595	DNA-templated transcription, initiation
H2N97_RS11795	COG5002	protein histidine kinase activity
H2N97_RS11800	COG0745	RESPONSE REGULATOR receiver
H2N97_RS11805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H2N97_RS11810	COG1333	cytochrome c biogenesis protein
H2N97_RS11815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H2N97_RS11820	COG1187	pseudouridine synthase activity
H2N97_RS11825	COG0700	Nucleoside recognition
H2N97_RS11830	COG2715	membrane protein required for spore maturation
H2N97_RS11835	COG1686	Belongs to the peptidase S11 family
H2N97_RS11860	COG1547	Domain of unknown function (DUF309)
H2N97_RS11865	COG0456	acetyltransferase
H2N97_RS11880	COG0307	riboflavin synthase, alpha
H2N97_RS11885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2N97_RS11885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2N97_RS11895	COG0681	Belongs to the peptidase S26 family
H2N97_RS11905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H2N97_RS11910	COG4086	secreted protein
H2N97_RS11915	COG0019	diaminopimelate decarboxylase activity
H2N97_RS11920	COG0697	spore germination
H2N97_RS11935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H2N97_RS11955	COG1191	sigma factor activity
H2N97_RS11965	COG1366	Belongs to the anti-sigma-factor antagonist family
H2N97_RS11970	COG1686	Belongs to the peptidase S11 family
H2N97_RS11975	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H2N97_RS11980	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H2N97_RS11985	COG4974	Belongs to the 'phage' integrase family
H2N97_RS11995	COG0735	belongs to the Fur family
H2N97_RS12000	COG1300	Membrane
H2N97_RS12015	COG0281	malic enzyme
H2N97_RS12020	COG1757	Na H antiporter
H2N97_RS12025	COG1027	Aspartate ammonia-lyase
H2N97_RS12030	COG0252	asparaginase activity
H2N97_RS12035	COG1396	sequence-specific DNA binding
H2N97_RS12040	COG1379	DNA repair
H2N97_RS12045	COG0494	nUDIX hydrolase
H2N97_RS12055	COG0667	Aldo Keto reductase
H2N97_RS12065	COG1073	alpha beta
H2N97_RS12075	COG4918	Iron-sulphur cluster biosynthesis
H2N97_RS12080	COG0456	acetyltransferase
H2N97_RS12080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H2N97_RS12085	COG2329	Antibiotic biosynthesis monooxygenase
H2N97_RS12090	COG0456	acetyltransferase
H2N97_RS12095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H2N97_RS12110	COG0628	permease
H2N97_RS12120	COG0346	lactoylglutathione lyase activity
H2N97_RS12130	COG3048	D-serine ammonia-lyase activity
H2N97_RS12135	COG0300	oxidoreductase activity
H2N97_RS12140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2N97_RS12145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H2N97_RS12150	COG1024	Enoyl-CoA hydratase
H2N97_RS12155	COG3425	synthase
H2N97_RS12160	COG2124	cytochrome p450
H2N97_RS12165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS12165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H2N97_RS12165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS12165	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS12165	COG3321	synthase
H2N97_RS12170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS12170	COG3321	synthase
H2N97_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS12170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS12170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H2N97_RS12175	COG3321	synthase
H2N97_RS12175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS12175	COG0300	oxidoreductase activity
H2N97_RS12175	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS12175	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS12180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS12180	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS12180	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS12180	COG0300	oxidoreductase activity
H2N97_RS12180	COG3321	synthase
H2N97_RS12190	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS12190	COG3321	synthase
H2N97_RS12190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS12190	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS12190	COG0300	oxidoreductase activity
H2N97_RS12195	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS12195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS12195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H2N97_RS12195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2N97_RS12195	COG3321	synthase
H2N97_RS12200	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS12205	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS12220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H2N97_RS12220	COG2070	2-Nitropropane dioxygenase
H2N97_RS12225	COG0250	Participates in transcription elongation, termination and antitermination
H2N97_RS12250	COG0596	Alpha beta hydrolase
H2N97_RS12265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H2N97_RS12270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H2N97_RS12285	COG0706	membrane insertase activity
H2N97_RS12290	COG2195	Cleaves the N-terminal amino acid of tripeptides
H2N97_RS12295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H2N97_RS12300	COG0346	lactoylglutathione lyase activity
H2N97_RS12310	COG1376	ErfK ybiS ycfS ynhG family protein
H2N97_RS12315	COG4129	membrane
H2N97_RS12320	COG1126	abc transporter atp-binding protein
H2N97_RS12325	COG0765	amino acid transport
H2N97_RS12330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2N97_RS12340	COG1597	lipid kinase activity
H2N97_RS12345	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2N97_RS12350	COG0022	dehydrogenase e1 component
H2N97_RS12355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H2N97_RS12360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2N97_RS12365	COG3426	butyrate kinase activity
H2N97_RS12370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2N97_RS12375	COG0280	phosphate acetyltransferase
H2N97_RS12380	COG3290	protein histidine kinase activity
H2N97_RS12380	COG3829	transcription factor binding
H2N97_RS12390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H2N97_RS12395	COG2079	MmgE PrpD family protein
H2N97_RS12400	COG0372	Belongs to the citrate synthase family
H2N97_RS12405	COG1960	acyl-CoA dehydrogenase activity
H2N97_RS12410	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2N97_RS12415	COG0183	Belongs to the thiolase family
H2N97_RS12420	COG0584	glycerophosphoryl diester phosphodiesterase
H2N97_RS12425	COG0860	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS12450	COG1902	pentaerythritol trinitrate reductase activity
H2N97_RS12465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H2N97_RS12470	COG0745	RESPONSE REGULATOR receiver
H2N97_RS12475	COG0750	zinc metalloprotease
H2N97_RS12480	COG0497	DNA recombination
H2N97_RS12490	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H2N97_RS12500	COG0142	geranyltranstransferase activity
H2N97_RS12510	COG1570	exodeoxyribonuclease VII activity
H2N97_RS12525	COG1302	Protein conserved in bacteria
H2N97_RS12530	COG0439	Biotin carboxylase
H2N97_RS12535	COG0511	ligase activity, forming carbon-carbon bonds
H2N97_RS12575	COG3854	ATPases associated with a variety of cellular activities
H2N97_RS12590	COG0006	proline dipeptidase activity
H2N97_RS12600	COG3872	metal-dependent enzyme
H2N97_RS12610	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2N97_RS12625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H2N97_RS12645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H2N97_RS12660	COG1396	sequence-specific DNA binding
H2N97_RS12670	COG0681	Belongs to the peptidase S26 family
H2N97_RS12695	COG4940	Competence protein ComGF
H2N97_RS12705	COG4970	Tfp pilus assembly protein FimT
H2N97_RS12710	COG4537	Required for transformation and DNA binding
H2N97_RS12715	COG1459	type II secretion system
H2N97_RS12720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H2N97_RS12725	COG0598	Magnesium transport protein CorA
H2N97_RS12730	COG1253	flavin adenine dinucleotide binding
H2N97_RS12735	COG1366	Belongs to the anti-sigma-factor antagonist family
H2N97_RS12745	COG1393	Belongs to the ArsC family
H2N97_RS12755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2N97_RS12765	COG0011	TIGRFAM Protein of
H2N97_RS12775	COG2866	Carboxypeptidase
H2N97_RS12780	COG1940	carbohydrate kinase activity
H2N97_RS12785	COG4483	Protein conserved in bacteria
H2N97_RS12790	COG1757	Na H antiporter
H2N97_RS12800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H2N97_RS12815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H2N97_RS12820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H2N97_RS12825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H2N97_RS12830	COG0581	inorganic phosphate transmembrane transporter activity
H2N97_RS12835	COG0573	inorganic phosphate transmembrane transporter activity
H2N97_RS12840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H2N97_RS12850	COG0477	Major facilitator Superfamily
H2N97_RS12855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H2N97_RS12860	COG2839	Protein conserved in bacteria
H2N97_RS12865	COG5521	maltodextrose utilization protein MalA
H2N97_RS12870	COG1388	LysM domain
H2N97_RS12880	COG4709	membrane
H2N97_RS12885	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
H2N97_RS12890	COG0735	belongs to the Fur family
H2N97_RS12895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H2N97_RS12910	COG0513	Belongs to the DEAD box helicase family
H2N97_RS12925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H2N97_RS12930	COG2384	SAM-dependent methyltransferase
H2N97_RS12935	COG2010	Cytochrome c
H2N97_RS12940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H2N97_RS12945	COG0358	DNA primase activity
H2N97_RS12960	COG0517	IMP dehydrogenase activity
H2N97_RS12965	COG0751	glycine-tRNA ligase activity
H2N97_RS12985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H2N97_RS12990	COG0295	cytidine deaminase activity
H2N97_RS12995	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H2N97_RS13005	COG1480	7TM receptor with intracellular HD hydrolase
H2N97_RS13010	COG1702	phosphate starvation-inducible protein PhoH
H2N97_RS13015	COG0561	phosphatase activity
H2N97_RS13030	COG4864	UPF0365 protein
H2N97_RS13035	COG1030	water channel activity
H2N97_RS13040	COG1610	YqeY-like protein
H2N97_RS13050	COG1283	sodium-dependent phosphate transmembrane transporter activity
H2N97_RS13055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H2N97_RS13060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H2N97_RS13090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H2N97_RS13105	COG0860	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS13120	COG1466	dna polymerase III delta subunit
H2N97_RS13135	COG2333	competence protein COMEC
H2N97_RS13135	COG0658	competence protein
H2N97_RS13140	COG2131	deaminase
H2N97_RS13145	COG1596	polysaccharide export
H2N97_RS13145	COG1555	photosystem II stabilization
H2N97_RS13150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H2N97_RS13155	COG2226	methyltransferase
H2N97_RS13160	COG0799	negative regulation of ribosome biogenesis
H2N97_RS13165	COG1713	HD superfamily hydrolase involved in NAD metabolism
H2N97_RS13175	COG1534	Rna-binding protein
H2N97_RS13180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H2N97_RS13185	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H2N97_RS13190	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H2N97_RS13200	COG2755	lipolytic protein G-D-S-L family
H2N97_RS13210	COG0398	Pfam SNARE associated Golgi protein
H2N97_RS13240	COG5444	nuclease activity
H2N97_RS13245	COG4282	regulation of fungal-type cell wall biogenesis
H2N97_RS13260	COG2207	Transcriptional regulator
H2N97_RS13260	COG3708	Transcriptional regulator
H2N97_RS13265	COG0583	DNA-binding transcription factor activity
H2N97_RS13280	COG0642	Histidine kinase
H2N97_RS13280	COG5002	protein histidine kinase activity
H2N97_RS13285	COG0745	RESPONSE REGULATOR receiver
H2N97_RS13290	COG2311	Membrane
H2N97_RS13300	COG0454	-acetyltransferase
H2N97_RS13305	COG0563	adenylate kinase activity
H2N97_RS13315	COG2814	Major facilitator Superfamily
H2N97_RS13325	COG0456	acetyltransferase
H2N97_RS13330	COG2318	DinB family
H2N97_RS13340	COG0561	phosphatase activity
H2N97_RS13345	COG0561	phosphatase activity
H2N97_RS13355	COG1482	cell wall glycoprotein biosynthetic process
H2N97_RS13360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2N97_RS13360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2N97_RS13360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2N97_RS13365	COG3711	transcriptional antiterminator
H2N97_RS13365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2N97_RS13375	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H2N97_RS13380	COG0583	DNA-binding transcription factor activity
H2N97_RS13385	COG2814	Major facilitator Superfamily
H2N97_RS13390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H2N97_RS13390	COG2124	cytochrome p450
H2N97_RS13395	COG1309	transcriptional regulator
H2N97_RS13400	COG2226	methyltransferase
H2N97_RS13415	COG2116	formate transmembrane transporter activity
H2N97_RS13420	COG5609	conserved protein (DUF2294)
H2N97_RS13425	COG3383	formate dehydrogenase (NAD+) activity
H2N97_RS13430	COG2427	Protein of unknown function (DUF1641)
H2N97_RS13445	COG0626	cystathionine gamma-synthase activity
H2N97_RS13450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H2N97_RS13475	COG0768	penicillin binding
H2N97_RS13500	COG4122	O-methyltransferase activity
H2N97_RS13505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H2N97_RS13520	COG4472	Bacterial protein of unknown function (DUF965)
H2N97_RS13530	COG0628	permease
H2N97_RS13535	COG1126	abc transporter atp-binding protein
H2N97_RS13540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2N97_RS13545	COG0765	amino acid transport
H2N97_RS13550	COG0765	amino acid transport
H2N97_RS13565	COG3881	PFAM PRC-barrel domain
H2N97_RS13570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2N97_RS13575	COG0457	Tetratricopeptide repeat
H2N97_RS13585	COG1104	cysteine desulfurase activity
H2N97_RS13590	COG1959	2 iron, 2 sulfur cluster binding
H2N97_RS13595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H2N97_RS13600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H2N97_RS13625	COG0860	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS13625	COG3103	Sh3 type 3 domain protein
H2N97_RS13625	COG4991	sh3 domain protein
H2N97_RS13635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H2N97_RS13645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H2N97_RS13645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H2N97_RS13650	COG5416	Lipopolysaccharide assembly protein A domain
H2N97_RS13655	COG0490	domain, Protein
H2N97_RS13660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H2N97_RS13660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H2N97_RS13670	COG2244	polysaccharide biosynthetic process
H2N97_RS13675	COG2323	membrane
H2N97_RS13685	COG1862	Preprotein translocase
H2N97_RS13725	COG1388	LysM domain
H2N97_RS13735	COG0157	Belongs to the NadC ModD family
H2N97_RS13740	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H2N97_RS13745	COG1104	cysteine desulfurase activity
H2N97_RS13750	COG1827	regulation of RNA biosynthetic process
H2N97_RS13755	COG0077	Prephenate dehydratase
H2N97_RS13770	COG3290	protein histidine kinase activity
H2N97_RS13775	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H2N97_RS13780	COG2868	ribosomal protein
H2N97_RS13790	COG1994	Peptidase M50
H2N97_RS13795	COG0739	heme binding
H2N97_RS13800	COG2894	cell division
H2N97_RS13810	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H2N97_RS13820	COG1077	Cell shape determining protein MreB Mrl
H2N97_RS13840	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H2N97_RS13845	COG0285	dihydrofolate synthase activity
H2N97_RS13850	COG0525	valine-tRNA ligase activity
H2N97_RS13860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H2N97_RS13865	COG1388	LysM domain
H2N97_RS13875	COG0113	porphobilinogen synthase activity
H2N97_RS13880	COG1587	Uroporphyrinogen-III synthase
H2N97_RS13890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H2N97_RS13910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H2N97_RS13915	COG0470	DNA polymerase III
H2N97_RS13915	COG1067	ATP-dependent peptidase activity
H2N97_RS13930	COG1477	protein flavinylation
H2N97_RS13930	COG0457	Tetratricopeptide repeat
H2N97_RS13945	COG0473	3-isopropylmalate dehydrogenase activity
H2N97_RS13960	COG0440	acetolactate synthase activity
H2N97_RS13965	COG0028	Belongs to the TPP enzyme family
H2N97_RS13995	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
H2N97_RS14020	COG0622	Phosphoesterase
H2N97_RS14025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H2N97_RS14035	COG5401	PFAM Sporulation and spore germination
H2N97_RS14045	COG1846	Transcriptional regulator
H2N97_RS14050	COG2197	response regulator
H2N97_RS14055	COG0824	Thioesterase
H2N97_RS14060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H2N97_RS14065	COG1053	succinate dehydrogenase
H2N97_RS14070	COG2009	succinate dehydrogenase
H2N97_RS14075	COG1719	4-vinyl reductase, 4VR
H2N97_RS14080	COG0527	aspartate kinase activity
H2N97_RS14090	COG3118	belongs to the thioredoxin family
H2N97_RS14095	COG3534	alpha-L-arabinofuranosidase
H2N97_RS14100	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H2N97_RS14105	COG2086	electron transfer activity
H2N97_RS14110	COG1024	Enoyl-CoA hydratase
H2N97_RS14115	COG1309	transcriptional regulator
H2N97_RS14120	COG0318	PFAM AMP-dependent synthetase and ligase
H2N97_RS14130	COG3766	membrane
H2N97_RS14140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H2N97_RS14140	COG1796	DNA polymerase
H2N97_RS14145	COG1286	toxin biosynthetic process
H2N97_RS14160	COG0072	phenylalanine-tRNA ligase activity
H2N97_RS14160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2N97_RS14165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H2N97_RS14170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2N97_RS14180	COG3835	regulator
H2N97_RS14185	COG0277	FAD linked oxidase domain protein
H2N97_RS14190	COG0247	lactate metabolic process
H2N97_RS14195	COG1966	Carbon starvation protein
H2N97_RS14200	COG3534	alpha-L-arabinofuranosidase
H2N97_RS14205	COG0395	ABC-type sugar transport system, permease component
H2N97_RS14210	COG1175	transmembrane transport
H2N97_RS14215	COG1653	transport
H2N97_RS14225	COG0647	UMP catabolic process
H2N97_RS14230	COG0235	Class ii aldolase
H2N97_RS14235	COG1069	ribulokinase activity
H2N97_RS14240	COG2160	L-arabinose isomerase activity
H2N97_RS14245	COG3507	Belongs to the glycosyl hydrolase 43 family
H2N97_RS14250	COG1363	Peptidase, m42
H2N97_RS14260	COG3326	Membrane
H2N97_RS14275	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H2N97_RS14280	COG1346	cytolysis
H2N97_RS14285	COG1380	Effector of murein hydrolase LrgA
H2N97_RS14290	COG3279	Response regulator of the LytR AlgR family
H2N97_RS14295	COG3275	phosphorelay sensor kinase activity
H2N97_RS14300	COG1011	Hydrolase
H2N97_RS14320	COG0398	Pfam SNARE associated Golgi protein
H2N97_RS14325	COG1484	DNA-dependent DNA replication
H2N97_RS14330	COG3611	Membrane attachment protein
H2N97_RS14345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H2N97_RS14350	COG1733	regulation of RNA biosynthetic process
H2N97_RS14355	COG2814	Major facilitator Superfamily
H2N97_RS14360	COG0656	L-ascorbic acid biosynthetic process
H2N97_RS14365	COG0237	dephospho-CoA kinase activity
H2N97_RS14370	COG1971	Probably functions as a manganese efflux pump
H2N97_RS14375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H2N97_RS14380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H2N97_RS14380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H2N97_RS14385	COG5002	protein histidine kinase activity
H2N97_RS14390	COG0745	RESPONSE REGULATOR receiver
H2N97_RS14400	COG0538	isocitrate dehydrogenase activity
H2N97_RS14405	COG0372	Belongs to the citrate synthase family
H2N97_RS14415	COG0457	Tetratricopeptide repeat
H2N97_RS14440	COG0628	permease
H2N97_RS14445	COG3030	protein affecting phage T7 exclusion by the F plasmid
H2N97_RS14450	COG0469	pyruvate kinase activity
H2N97_RS14470	COG0281	malic enzyme
H2N97_RS14475	COG0587	DNA-directed DNA polymerase activity
H2N97_RS14495	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H2N97_RS14505	COG4109	DRTGG domain
H2N97_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS14530	COG0521	Mo-molybdopterin cofactor biosynthetic process
H2N97_RS14540	COG0827	DNA restriction-modification system
H2N97_RS14545	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H2N97_RS14550	COG3874	Sporulation protein YtfJ
H2N97_RS14560	COG1714	RDD family
H2N97_RS14565	COG0616	signal peptide processing
H2N97_RS14570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H2N97_RS14575	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H2N97_RS14580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2N97_RS14595	COG1104	cysteine desulfurase activity
H2N97_RS14600	COG1114	Component of the transport system for branched-chain amino acids
H2N97_RS14615	COG1309	transcriptional regulator
H2N97_RS14620	COG1956	GAF domain-containing protein
H2N97_RS14625	COG2199	diguanylate cyclase activity
H2N97_RS14625	COG2203	Gaf domain
H2N97_RS14635	COG1012	belongs to the aldehyde dehydrogenase family
H2N97_RS14640	COG4282	regulation of fungal-type cell wall biogenesis
H2N97_RS14690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2N97_RS14690	COG1017	nitric oxide dioxygenase activity
H2N97_RS14700	COG0693	protein deglycase activity
H2N97_RS14715	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H2N97_RS14720	COG1378	Sugar-specific transcriptional regulator TrmB
H2N97_RS14740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2N97_RS14745	COG0454	-acetyltransferase
H2N97_RS14750	COG0517	IMP dehydrogenase activity
H2N97_RS14755	COG0123	including yeast histone deacetylase and acetoin utilization protein
H2N97_RS14760	COG1360	Flagellar Motor Protein
H2N97_RS14765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H2N97_RS14770	COG1609	Transcriptional regulator
H2N97_RS14775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H2N97_RS14775	COG1605	Chorismate mutase
H2N97_RS14780	COG3118	belongs to the thioredoxin family
H2N97_RS14785	COG4980	gas vesicle protein
H2N97_RS14790	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H2N97_RS14800	COG1674	ftsk spoiiie
H2N97_RS14805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2N97_RS14815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H2N97_RS14835	COG1363	Peptidase, m42
H2N97_RS14840	COG5584	Small secreted protein
H2N97_RS14845	COG0281	malic enzyme
H2N97_RS14850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2N97_RS14865	COG0510	thiamine kinase activity
H2N97_RS14870	COG1597	lipid kinase activity
H2N97_RS14880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H2N97_RS14885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H2N97_RS14890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H2N97_RS14895	COG2252	PERMEase
H2N97_RS14900	COG4473	ABC transporter
H2N97_RS14905	COG1131	(ABC) transporter
H2N97_RS14910	COG1349	DNA-binding transcription factor activity
H2N97_RS14915	COG1187	pseudouridine synthase activity
H2N97_RS14920	COG2244	polysaccharide biosynthetic process
H2N97_RS14925	COG2081	HI0933 family
H2N97_RS14930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2N97_RS14940	COG1609	Transcriptional regulator
H2N97_RS14945	COG1653	transport
H2N97_RS14950	COG1175	transmembrane transport
H2N97_RS14955	COG0395	ABC-type sugar transport system, permease component
H2N97_RS14960	COG1486	melibiose metabolic process
H2N97_RS14970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H2N97_RS14985	COG2202	Pas domain
H2N97_RS14985	COG1366	Belongs to the anti-sigma-factor antagonist family
H2N97_RS14990	COG2814	Major facilitator Superfamily
H2N97_RS14995	COG5522	Integral membrane protein (intg_mem_TP0381)
H2N97_RS15000	COG0577	efflux transmembrane transporter activity
H2N97_RS15005	COG1136	(ABC) transporter
H2N97_RS15010	COG2205	protein histidine kinase activity
H2N97_RS15015	COG0745	RESPONSE REGULATOR receiver
H2N97_RS15020	COG0577	efflux transmembrane transporter activity
H2N97_RS15025	COG1136	(ABC) transporter
H2N97_RS15045	COG1131	(ABC) transporter
H2N97_RS15050	COG1725	Transcriptional regulator
H2N97_RS15060	COG0640	Transcriptional regulator
H2N97_RS15065	COG0477	Major facilitator Superfamily
H2N97_RS15070	COG1242	4 iron, 4 sulfur cluster binding
H2N97_RS15075	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H2N97_RS15085	COG0584	glycerophosphoryl diester phosphodiesterase
H2N97_RS15095	COG2267	carboxylic ester hydrolase activity
H2N97_RS15100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H2N97_RS15105	COG1113	amino acid transport
H2N97_RS15110	COG0367	asparagine synthase
H2N97_RS15130	COG1506	peptidase
H2N97_RS15135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2N97_RS15140	COG1116	anion transmembrane transporter activity
H2N97_RS15145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2N97_RS15150	COG0494	nUDIX hydrolase
H2N97_RS15155	COG4824	toxin secretion phage lysis holin
H2N97_RS15160	COG0783	Belongs to the Dps family
H2N97_RS15185	COG0288	reversible hydration of carbon dioxide
H2N97_RS15195	COG1271	oxidase subunit
H2N97_RS15200	COG1294	oxidase, subunit
H2N97_RS15210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H2N97_RS15215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H2N97_RS15215	COG1321	iron dependent repressor
H2N97_RS15220	COG1121	(ABC) transporter
H2N97_RS15225	COG0803	Belongs to the bacterial solute-binding protein 9 family
H2N97_RS15230	COG4948	Mandelate Racemase Muconate Lactonizing
H2N97_RS15240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H2N97_RS15245	COG0596	Alpha beta hydrolase
H2N97_RS15255	COG1169	isochorismate synthase
H2N97_RS15260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H2N97_RS15265	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
H2N97_RS15390	COG3859	Proton-coupled thiamine transporter YuaJ
H2N97_RS15395	COG2268	Band 7 protein
H2N97_RS15400	COG1585	Membrane protein implicated in regulation of membrane protease activity
H2N97_RS15405	COG2318	DinB family
H2N97_RS15415	COG1454	alcohol dehydrogenase
H2N97_RS15420	COG1012	belongs to the aldehyde dehydrogenase family
H2N97_RS15425	COG1510	regulation of RNA biosynthetic process
H2N97_RS15435	COG0569	domain protein
H2N97_RS15440	COG1705	Flagellar rod assembly protein muramidase FlgJ
H2N97_RS15445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2N97_RS15445	COG1017	nitric oxide dioxygenase activity
H2N97_RS15470	COG5444	nuclease activity
H2N97_RS15485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H2N97_RS15500	COG0628	permease
H2N97_RS15505	COG0673	inositol 2-dehydrogenase activity
H2N97_RS15510	COG0693	protein deglycase activity
H2N97_RS15515	COG0840	transmembrane signaling receptor activity
H2N97_RS15520	COG0840	transmembrane signaling receptor activity
H2N97_RS15525	COG0840	transmembrane signaling receptor activity
H2N97_RS15530	COG0840	transmembrane signaling receptor activity
H2N97_RS15545	COG2070	2-Nitropropane dioxygenase
H2N97_RS15550	COG0432	Pfam Uncharacterised protein family UPF0047
H2N97_RS15555	COG0366	Alpha amylase catalytic
H2N97_RS15560	COG1253	flavin adenine dinucleotide binding
H2N97_RS15565	COG2738	Putative neutral zinc metallopeptidase
H2N97_RS15580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2N97_RS15605	COG1335	isochorismatase
H2N97_RS15615	COG1979	alcohol dehydrogenase
H2N97_RS15620	COG2155	Conserved Protein
H2N97_RS15625	COG1098	S1 RNA binding domain
H2N97_RS15630	COG0436	Aminotransferase
H2N97_RS15635	COG1522	sequence-specific DNA binding
H2N97_RS15640	COG2267	carboxylic ester hydrolase activity
H2N97_RS15650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H2N97_RS15655	COG2205	protein histidine kinase activity
H2N97_RS15665	COG5018	Exonuclease
H2N97_RS15670	COG2814	Major facilitator Superfamily
H2N97_RS15675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H2N97_RS15680	COG3011	Protein conserved in bacteria
H2N97_RS15690	COG3290	protein histidine kinase activity
H2N97_RS15695	COG4565	transcriptional regulatory protein
H2N97_RS15725	COG2111	Na H antiporter
H2N97_RS15725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H2N97_RS15730	COG2111	Na H antiporter
H2N97_RS15735	COG1006	Multisubunit Na H antiporter MnhC subunit
H2N97_RS15740	COG0651	ATP synthesis coupled electron transport
H2N97_RS15745	COG1863	multisubunit Na H antiporter MnhE subunit
H2N97_RS15750	COG2212	antiporter activity
H2N97_RS15755	COG1320	monovalent cation:proton antiporter activity
H2N97_RS15760	COG2050	protein possibly involved in aromatic compounds catabolism
H2N97_RS15765	COG2197	response regulator
H2N97_RS15770	COG4585	Histidine kinase
H2N97_RS15780	COG0142	geranyltranstransferase activity
H2N97_RS15795	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H2N97_RS15800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H2N97_RS15805	COG1335	isochorismatase
H2N97_RS15810	COG5506	Protein of unknown function (DUF1694)
H2N97_RS15825	COG0628	permease
H2N97_RS15835	COG1418	mRNA catabolic process
H2N97_RS15840	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS15850	COG1511	domain protein
H2N97_RS15855	COG1674	ftsk spoiiie
H2N97_RS15855	COG0433	COG0433 Predicted ATPase
H2N97_RS15860	COG4499	WXG100 protein secretion system (Wss), protein YukC
H2N97_RS15865	COG5417	Belongs to the EsaB family
H2N97_RS15870	COG4842	Belongs to the WXG100 family
H2N97_RS15875	COG2508	Transcriptional regulator
H2N97_RS15875	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H2N97_RS15880	COG0686	Belongs to the AlaDH PNT family
H2N97_RS15885	COG5634	Uncharacterized conserved protein (DUF2278)
H2N97_RS15890	COG3251	PFAM MbtH domain protein
H2N97_RS15895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2N97_RS15900	COG1535	isochorismatase
H2N97_RS15900	COG3433	isochorismatase activity
H2N97_RS15905	COG1021	2,3-dihydroxybenzoate-AMP ligase
H2N97_RS15910	COG1169	isochorismate synthase
H2N97_RS15915	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS15920	COG2819	hydrolase of the alpha beta superfamily
H2N97_RS15925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H2N97_RS15930	COG1268	BioY protein
H2N97_RS15935	COG2056	Na+-H+ antiporter family
H2N97_RS15945	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H2N97_RS15950	COG3584	3D domain protein
H2N97_RS15965	COG1252	NADH dehydrogenase
H2N97_RS15995	COG1131	(ABC) transporter
H2N97_RS16015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H2N97_RS16020	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H2N97_RS16025	COG0316	Belongs to the HesB IscA family
H2N97_RS16035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H2N97_RS16045	COG1252	NADH dehydrogenase
H2N97_RS16050	COG4837	Protein of unknown function (DUF1462)
H2N97_RS16055	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H2N97_RS16060	COG0823	Involved in the tonB-independent uptake of proteins
H2N97_RS16060	COG1506	peptidase
H2N97_RS16060	COG4946	Tricorn protease homolog
H2N97_RS16070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H2N97_RS16075	COG0460	homoserine dehydrogenase
H2N97_RS16080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H2N97_RS16085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H2N97_RS16090	COG0647	UMP catabolic process
H2N97_RS16095	COG2445	Protein of unknown function DUF86
H2N97_RS16100	COG4470	Protein conserved in bacteria
H2N97_RS16110	COG0739	heme binding
H2N97_RS16120	COG0737	Belongs to the 5'-nucleotidase family
H2N97_RS16125	COG0730	response to heat
H2N97_RS16130	COG1801	Protein of unknown function DUF72
H2N97_RS16145	COG2508	Transcriptional regulator
H2N97_RS16160	COG2814	Major facilitator Superfamily
H2N97_RS16165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H2N97_RS16170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H2N97_RS16175	COG2356	endonuclease I
H2N97_RS16180	COG3842	ATPase activity
H2N97_RS16185	COG2188	Transcriptional regulator
H2N97_RS16190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H2N97_RS16195	COG0395	ABC-type sugar transport system, permease component
H2N97_RS16200	COG1175	transmembrane transport
H2N97_RS16205	COG1653	transport
H2N97_RS16210	COG2222	sugar isomerase
H2N97_RS16215	COG0789	Transcriptional regulator
H2N97_RS16240	COG0322	excinuclease ABC activity
H2N97_RS16245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2N97_RS16250	COG2226	methyltransferase
H2N97_RS16260	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS16265	COG1388	LysM domain
H2N97_RS16265	COG5632	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS16265	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS16295	COG5434	Belongs to the glycosyl hydrolase 28 family
H2N97_RS16300	COG1705	Flagellar rod assembly protein muramidase FlgJ
H2N97_RS16310	COG5412	phage tail tape measure protein
H2N97_RS16310	COG3953	SLT domain
H2N97_RS16415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H2N97_RS16415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H2N97_RS16465	COG1396	sequence-specific DNA binding
H2N97_RS16475	COG4974	Belongs to the 'phage' integrase family
H2N97_RS16480	COG0719	Fe-S assembly protein
H2N97_RS16485	COG0822	iron-sulfur transferase activity
H2N97_RS16490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H2N97_RS16495	COG0719	Fe-S assembly protein
H2N97_RS16500	COG0396	ATPase activity
H2N97_RS16510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H2N97_RS16515	COG1464	Belongs to the NlpA lipoprotein family
H2N97_RS16520	COG2011	ABC-type metal ion transport system permease component
H2N97_RS16525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H2N97_RS16535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H2N97_RS16540	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H2N97_RS16555	COG1393	Belongs to the ArsC family
H2N97_RS16560	COG1960	acyl-CoA dehydrogenase activity
H2N97_RS16565	COG0183	Belongs to the thiolase family
H2N97_RS16570	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2N97_RS16570	COG1024	Enoyl-CoA hydratase
H2N97_RS16590	COG5577	PFAM Coat F domain
H2N97_RS16595	COG1846	Transcriptional regulator
H2N97_RS16600	COG0477	Major facilitator Superfamily
H2N97_RS16625	COG1120	ATPase activity
H2N97_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS16645	COG0783	Belongs to the Dps family
H2N97_RS16650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2N97_RS16655	COG0745	RESPONSE REGULATOR receiver
H2N97_RS16660	COG2770	Histidine kinase
H2N97_RS16660	COG2205	protein histidine kinase activity
H2N97_RS16670	COG1309	transcriptional regulator
H2N97_RS16675	COG0114	fumarate hydratase activity
H2N97_RS16685	COG0697	spore germination
H2N97_RS16690	COG0814	amino acid
H2N97_RS16700	COG2197	response regulator
H2N97_RS16705	COG4585	Histidine kinase
H2N97_RS16710	COG4758	membrane
H2N97_RS16715	COG3595	metallopeptidase activity
H2N97_RS16720	COG1842	Phage shock protein A
H2N97_RS16725	COG4758	membrane
H2N97_RS16730	COG2814	Major facilitator Superfamily
H2N97_RS16735	COG2096	Adenosyltransferase
H2N97_RS16740	COG1120	ATPase activity
H2N97_RS16745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2N97_RS16750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H2N97_RS16755	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS16760	COG3386	PFAM SMP-30 Gluconolaconase
H2N97_RS16765	COG2205	protein histidine kinase activity
H2N97_RS16770	COG0745	RESPONSE REGULATOR receiver
H2N97_RS16780	COG1191	sigma factor activity
H2N97_RS16790	COG2140	Oxalate decarboxylase
H2N97_RS16800	COG1120	ATPase activity
H2N97_RS16805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2N97_RS16810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2N97_RS16815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H2N97_RS16820	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H2N97_RS16825	COG0531	amino acid
H2N97_RS16835	COG1988	membrane-bound metal-dependent
H2N97_RS16845	COG1910	domain protein
H2N97_RS16850	COG0725	ABC transporter, periplasmic molybdate-binding protein
H2N97_RS16855	COG4149	molybdate abc transporter
H2N97_RS16860	COG2197	response regulator
H2N97_RS16865	COG3850	Histidine kinase
H2N97_RS16870	COG1131	(ABC) transporter
H2N97_RS16880	COG0842	Transport permease protein
H2N97_RS16885	COG0656	L-ascorbic acid biosynthetic process
H2N97_RS16905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H2N97_RS16910	COG3973	AAA domain
H2N97_RS16915	COG2860	membrane
H2N97_RS16925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H2N97_RS16930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2N97_RS16935	COG2217	Heavy metal translocating P-type atpase
H2N97_RS16940	COG2217	Heavy metal translocating P-type atpase
H2N97_RS16945	COG2608	mercury ion transmembrane transporter activity
H2N97_RS16950	COG1937	Protein conserved in bacteria
H2N97_RS16955	COG0673	inositol 2-dehydrogenase activity
H2N97_RS16965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2N97_RS16970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H2N97_RS16975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2N97_RS16980	COG1126	abc transporter atp-binding protein
H2N97_RS16985	COG0765	amino acid transport
H2N97_RS16990	COG0765	amino acid transport
H2N97_RS16995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2N97_RS17000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2N97_RS17005	COG0454	-acetyltransferase
H2N97_RS17015	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS17020	COG2732	(Barnase) inhibitor
H2N97_RS17025	COG2732	(Barnase) inhibitor
H2N97_RS17040	COG0557	exoribonuclease II activity
H2N97_RS17045	COG1647	Serine aminopeptidase, S33
H2N97_RS17050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H2N97_RS17055	COG1476	TRANSCRIPTIONal
H2N97_RS17060	COG1396	sequence-specific DNA binding
H2N97_RS17065	COG1396	sequence-specific DNA binding
H2N97_RS17070	COG1733	regulation of RNA biosynthetic process
H2N97_RS17095	COG1131	(ABC) transporter
H2N97_RS17100	COG1174	glycine betaine transport
H2N97_RS17105	COG1732	Glycine betaine
H2N97_RS17110	COG1174	glycine betaine transport
H2N97_RS17115	COG1125	glycine betaine transport
H2N97_RS17115	COG0517	IMP dehydrogenase activity
H2N97_RS17120	COG1510	regulation of RNA biosynthetic process
H2N97_RS17125	COG1174	glycine betaine transport
H2N97_RS17130	COG1732	Glycine betaine
H2N97_RS17135	COG1174	glycine betaine transport
H2N97_RS17140	COG1125	glycine betaine transport
H2N97_RS17140	COG0517	IMP dehydrogenase activity
H2N97_RS17145	COG1510	regulation of RNA biosynthetic process
H2N97_RS17150	COG2095	MarC family integral membrane protein
H2N97_RS17155	COG3064	Membrane
H2N97_RS17160	COG4640	response to antibiotic
H2N97_RS17165	COG0456	acetyltransferase
H2N97_RS17185	COG0126	phosphoglycerate kinase activity
H2N97_RS17190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H2N97_RS17195	COG2390	Transcriptional regulator
H2N97_RS17200	COG2814	Major facilitator Superfamily
H2N97_RS17205	COG1609	Transcriptional regulator
H2N97_RS17215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2N97_RS17220	COG0583	DNA-binding transcription factor activity
H2N97_RS17225	COG0697	spore germination
H2N97_RS17230	COG1113	amino acid transport
H2N97_RS17240	COG1609	Transcriptional regulator
H2N97_RS17250	COG0561	phosphatase activity
H2N97_RS17255	COG1737	Transcriptional regulator
H2N97_RS17260	COG1070	Carbohydrate kinase
H2N97_RS17285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2N97_RS17290	COG2186	Transcriptional regulator
H2N97_RS17295	COG1620	l-lactate permease
H2N97_RS17300	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H2N97_RS17310	COG5039	Polysaccharide pyruvyl transferase
H2N97_RS17315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H2N97_RS17320	COG0110	maltose O-acetyltransferase activity
H2N97_RS17325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H2N97_RS17330	COG2244	polysaccharide biosynthetic process
H2N97_RS17335	COG1216	Glycosyl transferase, family 2
H2N97_RS17340	COG5039	Polysaccharide pyruvyl transferase
H2N97_RS17345	COG1216	Glycosyl transferase, family 2
H2N97_RS17355	COG0438	transferase activity, transferring glycosyl groups
H2N97_RS17360	COG1215	transferase activity, transferring glycosyl groups
H2N97_RS17365	COG0438	transferase activity, transferring glycosyl groups
H2N97_RS17370	COG1086	Polysaccharide biosynthesis protein
H2N97_RS17375	COG0489	protein tyrosine kinase activity
H2N97_RS17380	COG3944	biosynthesis protein
H2N97_RS17385	COG1396	sequence-specific DNA binding
H2N97_RS17390	COG2272	Belongs to the type-B carboxylesterase lipase family
H2N97_RS17400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H2N97_RS17405	COG2364	Membrane
H2N97_RS17410	COG0456	acetyltransferase
H2N97_RS17415	COG3479	Phenolic acid decarboxylase
H2N97_RS17455	COG2223	nitrite transmembrane transporter activity
H2N97_RS17460	COG1609	Transcriptional regulator
H2N97_RS17470	COG0583	DNA-binding transcription factor activity
H2N97_RS17475	COG2828	Protein conserved in bacteria
H2N97_RS17480	COG2814	Major facilitator Superfamily
H2N97_RS17480	COG0477	Major facilitator Superfamily
H2N97_RS17485	COG1611	Belongs to the LOG family
H2N97_RS17490	COG1694	Mazg nucleotide pyrophosphohydrolase
H2N97_RS17495	COG0659	secondary active sulfate transmembrane transporter activity
H2N97_RS17500	COG0288	reversible hydration of carbon dioxide
H2N97_RS17505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H2N97_RS17510	COG4290	ribonuclease
H2N97_RS17515	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H2N97_RS17520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2N97_RS17530	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H2N97_RS17540	COG1051	belongs to the nudix hydrolase family
H2N97_RS17545	COG0492	ferredoxin-NADP+ reductase activity
H2N97_RS17550	COG0791	NLP P60 protein
H2N97_RS17550	COG3883	PFAM NLP P60 protein
H2N97_RS17555	COG0457	Tetratricopeptide repeat
H2N97_RS17560	COG5002	protein histidine kinase activity
H2N97_RS17565	COG0745	RESPONSE REGULATOR receiver
H2N97_RS17570	COG1132	(ABC) transporter
H2N97_RS17575	COG0140	phosphoribosyl-ATP diphosphatase activity
H2N97_RS17575	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H2N97_RS17600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H2N97_RS17615	COG4990	cell redox homeostasis
H2N97_RS17620	COG0110	maltose O-acetyltransferase activity
H2N97_RS17640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H2N97_RS17650	COG2188	Transcriptional regulator
H2N97_RS17655	COG1309	transcriptional regulator
H2N97_RS17660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H2N97_RS17665	COG1950	PFAM Membrane protein of
H2N97_RS17670	COG1983	PspC domain protein
H2N97_RS17675	COG3595	metallopeptidase activity
H2N97_RS17690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H2N97_RS17700	COG4897	Protein conserved in bacteria
H2N97_RS17705	COG0574	Belongs to the PEP-utilizing enzyme family
H2N97_RS17705	COG3848	Pyruvate phosphate dikinase
H2N97_RS17710	COG1309	transcriptional regulator
H2N97_RS17715	COG2814	Major facilitator Superfamily
H2N97_RS17730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2N97_RS17740	COG3409	Peptidoglycan-binding domain 1 protein
H2N97_RS17740	COG0793	Belongs to the peptidase S41A family
H2N97_RS17745	COG3420	alginic acid biosynthetic process
H2N97_RS17750	COG2177	Part of the ABC transporter FtsEX involved in
H2N97_RS17755	COG2884	Cell division ATP-binding protein ftsE
H2N97_RS17760	COG2010	Cytochrome c
H2N97_RS17765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H2N97_RS17780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H2N97_RS17795	COG1516	flagellar protein fliS
H2N97_RS17800	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H2N97_RS17805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H2N97_RS17825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H2N97_RS17830	COG1256	bacterial-type flagellum assembly
H2N97_RS17830	COG4786	Flagellar basal body rod
H2N97_RS17835	COG3418	PFAM FlgN family protein
H2N97_RS17840	COG2747	anti-sigma28 factor FlgM
H2N97_RS17850	COG1040	competence protein
H2N97_RS17860	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H2N97_RS17865	COG1307	EDD domain protein, DegV family
H2N97_RS17870	COG2197	response regulator
H2N97_RS17875	COG4585	Histidine kinase
H2N97_RS17880	COG1739	Uncharacterized protein family UPF0029
H2N97_RS17885	COG1316	TRANSCRIPTIONal
H2N97_RS17890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H2N97_RS17895	COG0438	transferase activity, transferring glycosyl groups
H2N97_RS17900	COG1215	transferase activity, transferring glycosyl groups
H2N97_RS17905	COG3206	protein involved in exopolysaccharide biosynthesis
H2N97_RS17910	COG3307	-O-antigen
H2N97_RS17915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H2N97_RS17920	COG0438	transferase activity, transferring glycosyl groups
H2N97_RS17920	COG0297	glycogen (starch) synthase activity
H2N97_RS17925	COG2244	polysaccharide biosynthetic process
H2N97_RS17935	COG0860	N-Acetylmuramoyl-L-alanine amidase
H2N97_RS17935	COG2247	cell wall binding repeat
H2N97_RS17940	COG2247	cell wall binding repeat
H2N97_RS17940	COG2385	sporulation resulting in formation of a cellular spore
H2N97_RS17950	COG1316	TRANSCRIPTIONal
H2N97_RS17955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H2N97_RS17960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H2N97_RS17965	COG1134	teichoic acid transport
H2N97_RS17970	COG1682	transport, permease protein
H2N97_RS17975	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H2N97_RS17980	COG0438	transferase activity, transferring glycosyl groups
H2N97_RS17985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H2N97_RS17990	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H2N97_RS17995	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H2N97_RS18000	COG4193	domain, Protein
H2N97_RS18005	COG1482	cell wall glycoprotein biosynthetic process
H2N97_RS18010	COG0697	spore germination
H2N97_RS18015	COG0814	amino acid
H2N97_RS18025	COG1215	transferase activity, transferring glycosyl groups
H2N97_RS18030	COG2814	Major facilitator Superfamily
H2N97_RS18035	COG1316	TRANSCRIPTIONal
H2N97_RS18040	COG0561	phosphatase activity
H2N97_RS18045	COG2433	Pfam Transposase IS66
H2N97_RS18050	COG0791	NLP P60 protein
H2N97_RS18060	COG2843	Capsule synthesis protein
H2N97_RS18070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H2N97_RS18075	COG0697	spore germination
H2N97_RS18080	COG0814	amino acid
H2N97_RS18090	COG1609	Transcriptional regulator
H2N97_RS18095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H2N97_RS18105	COG1129	ABC transporter
H2N97_RS18110	COG1172	Belongs to the binding-protein-dependent transport system permease family
H2N97_RS18115	COG1879	ABC-type sugar transport system periplasmic component
H2N97_RS18120	COG3103	Sh3 type 3 domain protein
H2N97_RS18125	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2N97_RS18130	COG3527	Alpha-acetolactate decarboxylase
H2N97_RS18135	COG0028	Belongs to the TPP enzyme family
H2N97_RS18140	COG0583	DNA-binding transcription factor activity
H2N97_RS18145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H2N97_RS18160	COG5337	Spore coat protein CotH
H2N97_RS18170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2N97_RS18180	COG0405	Gamma-glutamyltransferase
H2N97_RS18185	COG1522	sequence-specific DNA binding
H2N97_RS18190	COG2059	Chromate
H2N97_RS18195	COG2059	Chromate
H2N97_RS18205	COG0655	NAD(P)H dehydrogenase (quinone) activity
H2N97_RS18210	COG0583	DNA-binding transcription factor activity
H2N97_RS18255	COG3878	Protein conserved in bacteria
H2N97_RS18260	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H2N97_RS18265	COG4464	protein tyrosine phosphatase activity
H2N97_RS18270	COG0489	protein tyrosine kinase activity
H2N97_RS18275	COG3944	biosynthesis protein
H2N97_RS18285	COG4715	Zinc finger, swim domain protein
H2N97_RS18290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H2N97_RS18295	COG0561	phosphatase activity
H2N97_RS18300	COG1349	DNA-binding transcription factor activity
H2N97_RS18305	COG0629	single-stranded DNA binding
H2N97_RS18330	COG0457	Tetratricopeptide repeat
H2N97_RS18335	COG4786	Flagellar basal body rod
H2N97_RS18340	COG4786	Flagellar basal body rod
H2N97_RS18345	COG1077	Cell shape determining protein MreB Mrl
H2N97_RS18350	COG1609	Transcriptional regulator
H2N97_RS18355	COG1846	Transcriptional regulator
H2N97_RS18360	COG2814	Major facilitator Superfamily
H2N97_RS18365	COG1953	Uracil, thiamine, allantoin
H2N97_RS18370	COG0477	Major facilitator Superfamily
H2N97_RS18375	COG1335	isochorismatase
H2N97_RS18380	COG0004	ammonium transporteR
H2N97_RS18385	COG0347	Belongs to the P(II) protein family
H2N97_RS18390	COG0772	Belongs to the SEDS family
H2N97_RS18395	COG0671	phosphoesterase, PA-phosphatase related
H2N97_RS18405	COG0739	heme binding
H2N97_RS18410	COG1247	-acetyltransferase
H2N97_RS18425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2N97_RS18435	COG0726	polysaccharide deacetylase
H2N97_RS18440	COG1959	2 iron, 2 sulfur cluster binding
H2N97_RS18455	COG0831	urea catabolic process
H2N97_RS18465	COG1994	Peptidase M50
H2N97_RS18470	COG0457	Tetratricopeptide repeat
H2N97_RS18480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H2N97_RS18490	COG2304	oxidoreductase activity
H2N97_RS18495	COG2304	oxidoreductase activity
H2N97_RS18500	COG2385	sporulation resulting in formation of a cellular spore
H2N97_RS18505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H2N97_RS18515	COG4836	Membrane
H2N97_RS18585	COG0698	ribose 5-phosphate isomerase
H2N97_RS18590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H2N97_RS18600	COG0009	L-threonylcarbamoyladenylate synthase
H2N97_RS18605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H2N97_RS18625	COG2890	protein-(glutamine-N5) methyltransferase activity
H2N97_RS18630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H2N97_RS18635	COG0346	lactoylglutathione lyase activity
H2N97_RS18640	COG0789	Transcriptional regulator
H2N97_RS18645	COG0679	Auxin Efflux Carrier
H2N97_RS18650	COG0281	malic enzyme
H2N97_RS18665	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H2N97_RS18670	COG1494	fructose-1,6-bisphosphatase
H2N97_RS18675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H2N97_RS18685	COG0191	fructose-bisphosphate aldolase activity
H2N97_RS18690	COG2204	response regulator
H2N97_RS18695	COG4821	SIS domain
H2N97_RS18710	COG2181	nitrate reductase activity
H2N97_RS18710	COG0247	lactate metabolic process
H2N97_RS18715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2N97_RS18730	COG1132	(ABC) transporter
H2N97_RS18735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2N97_RS18745	COG2181	nitrate reductase activity
H2N97_RS18750	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H2N97_RS18755	COG1140	nitrate reductase beta subunit
H2N97_RS18760	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H2N97_RS18765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2N97_RS18775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2N97_RS18780	COG2223	nitrite transmembrane transporter activity
H2N97_RS18790	COG4506	Protein conserved in bacteria
H2N97_RS18795	COG0457	Tetratricopeptide repeat
H2N97_RS18805	COG0010	Belongs to the arginase family
H2N97_RS18810	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H2N97_RS18815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H2N97_RS18830	COG1994	Peptidase M50
H2N97_RS18835	COG1942	4-Oxalocrotonate Tautomerase
H2N97_RS18840	COG1846	Transcriptional regulator
H2N97_RS18850	COG0531	amino acid
H2N97_RS18855	COG3465	dGTPase activity
H2N97_RS18860	COG1078	dGTPase activity
H2N97_RS18875	COG1695	Transcriptional regulator
H2N97_RS18885	COG1131	(ABC) transporter
H2N97_RS18890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H2N97_RS18920	COG0583	DNA-binding transcription factor activity
H2N97_RS18925	COG2855	membrane
H2N97_RS18930	COG0280	phosphate acetyltransferase
H2N97_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS18945	COG0436	Aminotransferase
H2N97_RS18975	COG2814	Major facilitator Superfamily
H2N97_RS18980	COG2814	Major facilitator Superfamily
H2N97_RS18985	COG0833	amino acid
H2N97_RS18990	COG4187	Peptidase family M20/M25/M40
H2N97_RS18995	COG1012	belongs to the aldehyde dehydrogenase family
H2N97_RS19000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2N97_RS19005	COG2205	protein histidine kinase activity
H2N97_RS19010	COG0745	RESPONSE REGULATOR receiver
H2N97_RS19025	COG1131	(ABC) transporter
H2N97_RS19030	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
H2N97_RS19035	COG1091	dTDP-4-dehydrorhamnose reductase activity
H2N97_RS19040	COG1088	dTDP-glucose 4,6-dehydratase activity
H2N97_RS19045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H2N97_RS19050	COG3980	spore coat polysaccharide biosynthesis protein
H2N97_RS19055	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H2N97_RS19060	COG2089	acid synthase
H2N97_RS19065	COG0456	acetyltransferase
H2N97_RS19070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H2N97_RS19075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H2N97_RS19080	COG0463	Glycosyl transferase, family 2
H2N97_RS19090	COG2363	Small membrane protein
H2N97_RS19095	COG2233	PERMEase
H2N97_RS19110	COG1216	Glycosyl transferase, family 2
H2N97_RS19125	COG1695	Transcriptional regulator
H2N97_RS19130	COG0351	phosphomethylpyrimidine kinase
H2N97_RS19140	COG1621	beta-fructofuranosidase activity
H2N97_RS19145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H2N97_RS19145	COG1263	PTS System
H2N97_RS19150	COG3711	transcriptional antiterminator
H2N97_RS19160	COG1404	Belongs to the peptidase S8 family
H2N97_RS19165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2N97_RS19170	COG0778	Nitroreductase
H2N97_RS19175	COG0772	Belongs to the SEDS family
H2N97_RS19185	COG0454	-acetyltransferase
H2N97_RS19205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H2N97_RS19210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H2N97_RS19215	COG2261	transglycosylase associated protein
H2N97_RS19220	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H2N97_RS19230	COG2246	polysaccharide biosynthetic process
H2N97_RS19235	COG1309	transcriptional regulator
H2N97_RS19255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H2N97_RS19260	COG2837	iron assimilation
H2N97_RS19265	COG2822	iron ion transport
H2N97_RS19280	COG0583	DNA-binding transcription factor activity
H2N97_RS19290	COG1346	cytolysis
H2N97_RS19295	COG4895	conserved protein (DUF2196)
H2N97_RS19300	COG0789	Transcriptional regulator
H2N97_RS19305	COG5504	Zn-dependent protease
H2N97_RS19310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H2N97_RS19315	COG0346	lactoylglutathione lyase activity
H2N97_RS19320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H2N97_RS19325	COG1404	Belongs to the peptidase S8 family
H2N97_RS19330	COG1442	glycosyl transferase family 8
H2N97_RS19335	COG2357	RelA SpoT domain protein
H2N97_RS19340	COG1575	Belongs to the MenA family. Type 1 subfamily
H2N97_RS19355	COG1696	Membrane protein involved in D-alanine export
H2N97_RS19365	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H2N97_RS19370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H2N97_RS19375	COG1486	melibiose metabolic process
H2N97_RS19380	COG1447	Phosphotransferase system cellobiose-specific component IIA
H2N97_RS19385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H2N97_RS19390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H2N97_RS19395	COG3711	transcriptional antiterminator
H2N97_RS19395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2N97_RS19405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2N97_RS19410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2N97_RS19420	COG0640	Transcriptional regulator
H2N97_RS19425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H2N97_RS19430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H2N97_RS19435	COG1447	Phosphotransferase system cellobiose-specific component IIA
H2N97_RS19440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H2N97_RS19445	COG2723	6-phospho-beta-galactosidase activity
H2N97_RS19450	COG1940	carbohydrate kinase activity
H2N97_RS19455	COG1482	cell wall glycoprotein biosynthetic process
H2N97_RS19465	COG0753	catalase activity
H2N97_RS19470	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
H2N97_RS19475	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H2N97_RS19480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H2N97_RS19485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H2N97_RS19490	COG4988	ABC transporter
H2N97_RS19495	COG1294	oxidase, subunit
H2N97_RS19500	COG1271	oxidase subunit
H2N97_RS19505	COG3493	citrate carrier protein
H2N97_RS19510	COG0726	polysaccharide deacetylase
H2N97_RS19515	COG3842	ATPase activity
H2N97_RS19520	COG2508	Transcriptional regulator
H2N97_RS19525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H2N97_RS19535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H2N97_RS19550	COG4894	glucomannan catabolic process
H2N97_RS19555	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H2N97_RS19560	COG0500	methyltransferase
H2N97_RS19565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H2N97_RS19580	COG0693	protein deglycase activity
H2N97_RS19580	COG0753	catalase activity
H2N97_RS19585	COG2851	Citrate transporter
H2N97_RS19590	COG2273	Hydrolase Family 16
H2N97_RS19600	COG2270	Major facilitator Superfamily
H2N97_RS19605	COG0513	Belongs to the DEAD box helicase family
H2N97_RS19705	COG0697	spore germination
H2N97_RS19710	COG0589	response to stress
H2N97_RS19720	COG0494	nUDIX hydrolase
H2N97_RS19725	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
H2N97_RS19730	COG3507	Belongs to the glycosyl hydrolase 43 family
H2N97_RS19755	COG0010	Belongs to the arginase family
H2N97_RS19765	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H2N97_RS19770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H2N97_RS19780	COG2390	Transcriptional regulator
H2N97_RS19810	COG1131	(ABC) transporter
H2N97_RS19820	COG0561	phosphatase activity
H2N97_RS19850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H2N97_RS19855	COG5294	Protein conserved in bacteria
H2N97_RS19860	COG0577	efflux transmembrane transporter activity
H2N97_RS19865	COG1136	(ABC) transporter
H2N97_RS19870	COG2205	protein histidine kinase activity
H2N97_RS19875	COG0745	RESPONSE REGULATOR receiver
H2N97_RS19890	COG1082	Xylose isomerase domain protein TIM barrel
H2N97_RS19900	COG2814	Major facilitator Superfamily
H2N97_RS19930	COG1349	DNA-binding transcription factor activity
H2N97_RS19935	COG0667	Aldo Keto reductase
H2N97_RS19940	COG2814	Major facilitator Superfamily
H2N97_RS19950	COG1028	Short-chain dehydrogenase reductase Sdr
H2N97_RS19955	COG2197	response regulator
H2N97_RS19960	COG4585	Histidine kinase
H2N97_RS19965	COG3239	Fatty acid desaturase
H2N97_RS19970	COG1309	transcriptional regulator
H2N97_RS19980	COG1476	TRANSCRIPTIONal
H2N97_RS20010	COG1012	belongs to the aldehyde dehydrogenase family
H2N97_RS20025	COG0640	Transcriptional regulator
H2N97_RS20030	COG2814	Major facilitator Superfamily
H2N97_RS20035	COG1714	RDD family
H2N97_RS20045	COG0450	alkyl hydroperoxide reductase
H2N97_RS20050	COG3634	alkyl hydroperoxide reductase activity
H2N97_RS20055	COG3177	Filamentation induced by cAMP protein fic
H2N97_RS20060	COG1113	amino acid transport
H2N97_RS20070	COG2080	2 iron, 2 sulfur cluster binding
H2N97_RS20085	COG2068	MobA-Related Protein
H2N97_RS20090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H2N97_RS20100	COG1204	response to ionizing radiation
H2N97_RS20130	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
H2N97_RS20135	COG0667	Aldo Keto reductase
H2N97_RS20140	COG0456	acetyltransferase
H2N97_RS20145	COG0457	Tetratricopeptide repeat
H2N97_RS20150	COG0010	Belongs to the arginase family
H2N97_RS20155	COG0833	amino acid
H2N97_RS20160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H2N97_RS20165	COG5658	integral membrane protein
H2N97_RS20170	COG0640	Transcriptional regulator
H2N97_RS20175	COG3829	transcription factor binding
H2N97_RS20185	COG0488	(ABC) transporter
H2N97_RS20200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H2N97_RS20205	COG5002	protein histidine kinase activity
H2N97_RS20205	COG3850	Histidine kinase
H2N97_RS20210	COG0745	RESPONSE REGULATOR receiver
H2N97_RS20220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2N97_RS20225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H2N97_RS20230	COG4853	Protein conserved in bacteria
H2N97_RS20235	COG4863	YycH protein
H2N97_RS20240	COG5002	protein histidine kinase activity
H2N97_RS20245	COG0745	RESPONSE REGULATOR receiver
H2N97_RS20275	COG0346	lactoylglutathione lyase activity
H2N97_RS20280	COG0305	Participates in initiation and elongation during chromosome replication
H2N97_RS20295	COG3093	addiction module antidote protein HigA
H2N97_RS20300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H2N97_RS20305	COG0297	glycogen (starch) synthase activity
H2N97_RS20315	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H2N97_RS20325	COG0438	transferase activity, transferring glycosyl groups
H2N97_RS20335	COG2112	serine threonine protein kinase
H2N97_RS20345	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H2N97_RS20350	COG4241	membrane
H2N97_RS20360	COG5577	PFAM Coat F domain
H2N97_RS20365	COG1733	regulation of RNA biosynthetic process
H2N97_RS20375	COG0697	spore germination
H2N97_RS20380	COG1621	beta-fructofuranosidase activity
H2N97_RS20385	COG1621	beta-fructofuranosidase activity
H2N97_RS20390	COG1802	Transcriptional regulator
H2N97_RS20395	COG2318	DinB family
H2N97_RS20400	COG2211	Major facilitator Superfamily
H2N97_RS20410	COG0778	Nitroreductase
H2N97_RS20415	COG1846	Transcriptional regulator
H2N97_RS20420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H2N97_RS20425	COG1846	Transcriptional regulator
H2N97_RS20430	COG2153	protein acetylation
H2N97_RS20435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2N97_RS20440	COG0697	spore germination
H2N97_RS20450	COG4978	Transcriptional regulator
H2N97_RS20450	COG0789	Transcriptional regulator
H2N97_RS20455	COG1811	Na channel or pump
H2N97_RS20460	COG1331	Highly conserved protein containing a thioredoxin domain
H2N97_RS20465	COG1331	Highly conserved protein containing a thioredoxin domain
H2N97_RS20470	COG1266	CAAX protease self-immunity
H2N97_RS20475	COG2814	Major facilitator Superfamily
H2N97_RS20475	COG0477	Major facilitator Superfamily
H2N97_RS20480	COG0346	lactoylglutathione lyase activity
H2N97_RS20485	COG1609	Transcriptional regulator
H2N97_RS20490	COG0708	Exodeoxyribonuclease III
H2N97_RS20495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2N97_RS20500	COG2169	Transcriptional regulator
H2N97_RS20510	COG0629	single-stranded DNA binding
H2N97_RS20520	COG0012	GTP binding
H2N97_RS20525	COG0243	molybdopterin cofactor binding
H2N97_RS20530	COG4481	Protein conserved in bacteria
H2N97_RS20535	COG3949	Membrane
H2N97_RS20550	COG1475	DNA binding
H2N97_RS20555	COG1192	Involved in chromosome partitioning
H2N97_RS20580	COG1847	R3H domain protein
H2N97_RS20585	COG0706	membrane insertase activity