locus-tag	class	description
CK238_RS00010	COG0592	DNA-directed DNA polymerase activity
CK238_RS00015	COG2501	S4 domain
CK238_RS00030	COG0187	DNA topoisomerase II activity
CK238_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CK238_RS00070	COG0517	IMP dehydrogenase activity
CK238_RS00070	COG0516	GMP reductase activity
CK238_RS00075	COG1686	Belongs to the peptidase S11 family
CK238_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
CK238_RS00105	COG1428	Deoxynucleoside kinase
CK238_RS00110	COG1428	Deoxynucleoside kinase
CK238_RS00115	COG1388	LysM domain
CK238_RS00115	COG3858	chitin binding
CK238_RS00120	COG1335	isochorismatase
CK238_RS00125	COG0590	tRNA wobble adenosine to inosine editing
CK238_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CK238_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CK238_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CK238_RS00195	COG3853	Toxic anion resistance protein (TelA)
CK238_RS00200	COG1982	Orn Lys Arg decarboxylase major
CK238_RS00210	COG3870	Protein conserved in bacteria
CK238_RS00215	COG1728	Protein conserved in bacteria
CK238_RS00220	COG0470	DNA polymerase III
CK238_RS00225	COG1774	PSP1 C-terminal conserved region
CK238_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CK238_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CK238_RS00250	COG2002	toxin-antitoxin pair type II binding
CK238_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK238_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK238_RS00260	COG0084	hydrolase, TatD family'
CK238_RS00265	COG3584	3D domain protein
CK238_RS00265	COG3583	domain protein
CK238_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CK238_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CK238_RS00285	COG4466	Protein conserved in bacteria
CK238_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CK238_RS00305	COG0251	oxidation-reduction process
CK238_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CK238_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CK238_RS00345	COG2002	toxin-antitoxin pair type II binding
CK238_RS00350	COG2244	polysaccharide biosynthetic process
CK238_RS00355	COG3956	TIGRFAM MazG family protein
CK238_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CK238_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CK238_RS00380	COG1098	S1 RNA binding domain
CK238_RS00395	COG2208	phosphoserine phosphatase activity
CK238_RS00400	COG2304	oxidoreductase activity
CK238_RS00405	COG0515	serine threonine protein kinase
CK238_RS00410	COG0037	tRNA processing
CK238_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CK238_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CK238_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK238_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK238_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK238_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
CK238_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK238_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CK238_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CK238_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CK238_RS00475	COG1396	sequence-specific DNA binding
CK238_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK238_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CK238_RS00570	COG4463	regulation of RNA biosynthetic process
CK238_RS00575	COG3880	PFAM UvrB UvrC protein
CK238_RS00585	COG0542	response to heat
CK238_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CK238_RS00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CK238_RS00600	COG4956	integral membrane protein (PIN domain superfamily)
CK238_RS00620	COG1045	serine acetyltransferase
CK238_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CK238_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK238_RS00640	COG3688	RNA-binding protein containing a PIN domain
CK238_RS00645	COG1595	DNA-templated transcription, initiation
CK238_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK238_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
CK238_RS00685	COG2813	Specifically methylates the guanine in position
CK238_RS00700	COG1358	cellular component organization or biogenesis
CK238_RS00725	COG0596	Alpha beta hydrolase
CK238_RS00835	COG0201	protein transport
CK238_RS00845	COG0024	Methionine aminopeptidase
CK238_RS00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CK238_RS00885	COG1122	ATPase activity
CK238_RS00890	COG1122	ATPase activity
CK238_RS00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CK238_RS00915	COG2226	methyltransferase
CK238_RS00920	COG2318	DinB family
CK238_RS00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK238_RS00935	COG0489	protein tyrosine kinase activity
CK238_RS00945	COG2194	sulfuric ester hydrolase activity
CK238_RS00950	COG0726	polysaccharide deacetylase
CK238_RS01010	COG0738	Major facilitator superfamily
CK238_RS01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CK238_RS01025	COG1063	alcohol dehydrogenase
CK238_RS01030	COG0659	secondary active sulfate transmembrane transporter activity
CK238_RS01035	COG0385	Bile acid
CK238_RS01040	COG2819	hydrolase of the alpha beta superfamily
CK238_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK238_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK238_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK238_RS01060	COG2207	Transcriptional regulator
CK238_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK238_RS01065	COG3876	Protein conserved in bacteria
CK238_RS01070	COG1472	Belongs to the glycosyl hydrolase 3 family
CK238_RS01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK238_RS01080	COG1263	PTS System
CK238_RS01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK238_RS01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK238_RS01095	COG1683	Conserved Protein
CK238_RS01125	COG1595	DNA-templated transcription, initiation
CK238_RS01130	COG5662	AntiSigma factor
CK238_RS01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CK238_RS01140	COG4856	YbbR-like protein
CK238_RS01180	COG1063	alcohol dehydrogenase
CK238_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS01230	COG1346	cytolysis
CK238_RS01235	COG1380	Effector of murein hydrolase LrgA
CK238_RS01240	COG1846	Transcriptional regulator
CK238_RS01245	COG1113	amino acid transport
CK238_RS01250	COG1011	Hydrolase
CK238_RS01255	COG4585	Histidine kinase
CK238_RS01260	COG2197	response regulator
CK238_RS01265	COG1131	(ABC) transporter
CK238_RS01305	COG0531	amino acid
CK238_RS01330	COG0584	glycerophosphoryl diester phosphodiesterase
CK238_RS01335	COG2271	Major facilitator Superfamily
CK238_RS01350	COG2368	4-hydroxyphenylacetate
CK238_RS01360	COG3409	Peptidoglycan-binding domain 1 protein
CK238_RS01375	COG0371	Dehydrogenase
CK238_RS01390	COG1183	phosphatidylcholine synthase activity
CK238_RS01395	COG0586	Pfam SNARE associated Golgi protein
CK238_RS01400	COG0688	phosphatidylethanolamine metabolic process
CK238_RS01415	COG1301	dicarboxylic acid transport
CK238_RS01420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK238_RS01425	COG0833	amino acid
CK238_RS01430	COG2040	homocysteine
CK238_RS01435	COG1115	amino acid carrier protein
CK238_RS01440	COG2066	Belongs to the glutaminase family
CK238_RS01445	COG4191	Histidine kinase
CK238_RS01450	COG0784	Response regulator, receiver
CK238_RS01455	COG3173	Aminoglycoside phosphotransferase
CK238_RS01475	COG3773	Cell wall hydrolase
CK238_RS01485	COG3540	Alkaline phosphatase
CK238_RS01490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CK238_RS01495	COG0805	protein transport
CK238_RS01505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CK238_RS01510	COG0477	Major facilitator Superfamily
CK238_RS01515	COG1309	transcriptional regulator
CK238_RS01520	COG0252	asparaginase activity
CK238_RS01525	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CK238_RS01530	COG1405	negative regulation of cell septum assembly
CK238_RS01530	COG3012	SEC-C Motif Domain Protein
CK238_RS01535	COG0667	Aldo Keto reductase
CK238_RS01545	COG1595	DNA-templated transcription, initiation
CK238_RS01550	COG1595	DNA-templated transcription, initiation
CK238_RS01555	COG1876	peptidase activity
CK238_RS01560	COG0457	Tetratricopeptide repeat
CK238_RS01565	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS01580	COG0366	Alpha amylase catalytic
CK238_RS01585	COG0803	Belongs to the bacterial solute-binding protein 9 family
CK238_RS01590	COG1121	(ABC) transporter
CK238_RS01595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CK238_RS01600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK238_RS01605	COG2310	stress, protein
CK238_RS01610	COG2310	stress, protein
CK238_RS01615	COG2310	stress, protein
CK238_RS01620	COG0861	Integral membrane protein TerC family
CK238_RS01630	COG3853	Toxic anion resistance protein (TelA)
CK238_RS01635	COG0477	Major facilitator Superfamily
CK238_RS01640	COG4175	Glycine betaine
CK238_RS01640	COG0517	IMP dehydrogenase activity
CK238_RS01645	COG4176	ABC-type proline glycine betaine transport system permease component
CK238_RS01650	COG2113	Glycine betaine
CK238_RS01655	COG1473	amidohydrolase
CK238_RS01660	COG1288	antiporter activity
CK238_RS01680	COG2814	Major facilitator Superfamily
CK238_RS01685	COG1846	Transcriptional regulator
CK238_RS01690	COG1280	lysine exporter protein (LysE YggA)
CK238_RS01695	COG3403	YqcI/YcgG family
CK238_RS01700	COG1113	amino acid transport
CK238_RS01705	COG3665	Urea carboxylase-associated protein
CK238_RS01720	COG1660	Displays ATPase and GTPase activities
CK238_RS01730	COG2271	Major facilitator Superfamily
CK238_RS01735	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CK238_RS01745	COG3541	Predicted nucleotidyltransferase
CK238_RS01750	COG0506	proline dehydrogenase activity
CK238_RS01755	COG1012	belongs to the aldehyde dehydrogenase family
CK238_RS01760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK238_RS01765	COG2508	Transcriptional regulator
CK238_RS01775	COG1587	Uroporphyrinogen-III synthase
CK238_RS01775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK238_RS01780	COG2146	nitrite reductase [NAD(P)H] activity
CK238_RS01785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK238_RS01795	COG0523	cobalamin synthesis protein
CK238_RS01800	COG1063	alcohol dehydrogenase
CK238_RS01805	COG1714	RDD family
CK238_RS01815	COG2723	6-phospho-beta-galactosidase activity
CK238_RS01825	COG3209	COG3209 Rhs family protein
CK238_RS01830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CK238_RS01835	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CK238_RS01840	COG1733	regulation of RNA biosynthetic process
CK238_RS01850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS01855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS01860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS01865	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CK238_RS01880	COG2364	Membrane
CK238_RS01885	COG1126	abc transporter atp-binding protein
CK238_RS01890	COG0765	amino acid transport
CK238_RS01895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK238_RS01900	COG0583	DNA-binding transcription factor activity
CK238_RS01905	COG0163	prenyltransferase activity
CK238_RS01910	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CK238_RS01925	COG3104	oligopeptide transport
CK238_RS01930	COG5434	Belongs to the glycosyl hydrolase 28 family
CK238_RS01940	COG0697	spore germination
CK238_RS01950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CK238_RS01955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK238_RS01960	COG0456	acetyltransferase
CK238_RS01965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK238_RS01970	COG0765	amino acid transport
CK238_RS01975	COG1126	abc transporter atp-binding protein
CK238_RS01980	COG1473	amidohydrolase
CK238_RS01985	COG2079	MmgE PrpD family protein
CK238_RS01990	COG1136	(ABC) transporter
CK238_RS01995	COG0577	efflux transmembrane transporter activity
CK238_RS02000	COG0745	RESPONSE REGULATOR receiver
CK238_RS02005	COG5002	protein histidine kinase activity
CK238_RS02005	COG3850	Histidine kinase
CK238_RS02010	COG0457	Tetratricopeptide repeat
CK238_RS02025	COG0527	aspartate kinase activity
CK238_RS02035	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK238_RS02040	COG4605	iron ion homeostasis
CK238_RS02045	COG4604	ABC transporter, ATP-binding protein
CK238_RS02050	COG4607	ABC-type enterochelin transport system periplasmic component
CK238_RS02055	COG2814	Major facilitator Superfamily
CK238_RS02060	COG1309	transcriptional regulator
CK238_RS02065	COG0778	Nitroreductase
CK238_RS02070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CK238_RS02075	COG0640	Transcriptional regulator
CK238_RS02080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK238_RS02085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CK238_RS02090	COG1012	belongs to the aldehyde dehydrogenase family
CK238_RS02095	COG4975	Glucose uptake
CK238_RS02100	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS02105	COG4549	nuclear export factor GLE1
CK238_RS02110	COG1276	copper resistance
CK238_RS02110	COG2372	response to copper ion
CK238_RS02115	COG1349	DNA-binding transcription factor activity
CK238_RS02125	COG2213	PTS system mannitol-specific
CK238_RS02130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK238_RS02140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CK238_RS02150	COG0561	phosphatase activity
CK238_RS02160	COG1914	H( )-stimulated, divalent metal cation uptake system
CK238_RS02170	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CK238_RS02175	COG1984	allophanate hydrolase subunit 2
CK238_RS02180	COG1414	Transcriptional regulator
CK238_RS02185	COG2755	lipolytic protein G-D-S-L family
CK238_RS02195	COG2329	Antibiotic biosynthesis monooxygenase
CK238_RS02200	COG0768	penicillin binding
CK238_RS02205	COG4989	oxidoreductase activity
CK238_RS02210	COG3711	transcriptional antiterminator
CK238_RS02215	COG0318	PFAM AMP-dependent synthetase and ligase
CK238_RS02220	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS02225	COG1917	Cupin 2, conserved barrel domain protein
CK238_RS02230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK238_RS02235	COG3871	stress protein (general stress protein 26)
CK238_RS02245	COG2814	Major facilitator Superfamily
CK238_RS02250	COG1522	sequence-specific DNA binding
CK238_RS02255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK238_RS02255	COG0551	DNA topoisomerase type I activity
CK238_RS02260	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CK238_RS02265	COG3706	GGDEF domain
CK238_RS02270	COG5298	Protein conserved in bacteria
CK238_RS02275	COG1215	transferase activity, transferring glycosyl groups
CK238_RS02285	COG0531	amino acid
CK238_RS02290	COG0494	nUDIX hydrolase
CK238_RS02295	COG0028	Belongs to the TPP enzyme family
CK238_RS02325	COG1914	H( )-stimulated, divalent metal cation uptake system
CK238_RS02340	COG4876	unkown
CK238_RS02350	COG2076	Multidrug Resistance protein
CK238_RS02355	COG2217	Heavy metal translocating P-type atpase
CK238_RS02360	COG3729	General stress protein
CK238_RS02365	COG0662	Cupin 2, conserved barrel domain protein
CK238_RS02370	COG2329	Antibiotic biosynthesis monooxygenase
CK238_RS02375	COG3546	catalase activity
CK238_RS02380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CK238_RS02385	COG3290	protein histidine kinase activity
CK238_RS02390	COG4565	transcriptional regulatory protein
CK238_RS02395	COG1301	dicarboxylic acid transport
CK238_RS02400	COG0628	permease
CK238_RS02405	COG1131	(ABC) transporter
CK238_RS02410	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CK238_RS02420	COG1960	acyl-CoA dehydrogenase activity
CK238_RS02435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CK238_RS02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK238_RS02450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CK238_RS02455	COG0513	Belongs to the DEAD box helicase family
CK238_RS02460	COG3402	PFAM membrane-flanked domain
CK238_RS02465	COG3428	Bacterial PH domain
CK238_RS02470	COG0705	Rhomboid family
CK238_RS02480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CK238_RS02485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK238_RS02490	COG0864	Transcriptional regulator
CK238_RS02495	COG2337	Toxic component of a toxin-antitoxin (TA) module
CK238_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
CK238_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
CK238_RS02510	COG2172	sigma factor antagonist activity
CK238_RS02515	COG2208	phosphoserine phosphatase activity
CK238_RS02520	COG1366	Belongs to the anti-sigma-factor antagonist family
CK238_RS02530	COG1191	sigma factor activity
CK238_RS02535	COG2208	phosphoserine phosphatase activity
CK238_RS02540	COG2183	response to ionizing radiation
CK238_RS02590	COG0582	viral genome integration into host DNA
CK238_RS02595	COG2856	Zn peptidase
CK238_RS02600	COG1396	sequence-specific DNA binding
CK238_RS02625	COG1674	ftsk spoiiie
CK238_RS02630	COG2946	Replication initiation factor
CK238_RS02685	COG0433	COG0433 Predicted ATPase
CK238_RS02695	COG5644	endopeptidase inhibitor activity
CK238_RS02700	COG0741	lytic transglycosylase activity
CK238_RS02700	COG0791	NLP P60 protein
CK238_RS02720	COG0457	Tetratricopeptide repeat
CK238_RS02725	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK238_RS02730	COG0457	Tetratricopeptide repeat
CK238_RS02740	COG0477	Major facilitator Superfamily
CK238_RS02760	COG2030	dehydratase
CK238_RS02775	COG1959	2 iron, 2 sulfur cluster binding
CK238_RS02780	COG2910	NAD(P)H-binding
CK238_RS02790	COG1309	transcriptional regulator
CK238_RS02795	COG3239	Fatty acid desaturase
CK238_RS02805	COG1278	Cold shock
CK238_RS02810	COG1329	Transcriptional regulator
CK238_RS02815	COG1794	racemase activity, acting on amino acids and derivatives
CK238_RS02830	COG3621	Patatin-like phospholipase
CK238_RS02840	COG0662	Cupin 2, conserved barrel domain protein
CK238_RS02855	COG0277	FAD linked oxidase domain protein
CK238_RS02880	COG0662	Cupin 2, conserved barrel domain protein
CK238_RS02885	COG2318	DinB family
CK238_RS02890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK238_RS02910	COG1064	alcohol dehydrogenase
CK238_RS02915	COG0789	Transcriptional regulator
CK238_RS02925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK238_RS02940	COG2814	Major facilitator Superfamily
CK238_RS02945	COG1309	transcriptional regulator
CK238_RS02950	COG0697	spore germination
CK238_RS02955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK238_RS02960	COG5577	PFAM Coat F domain
CK238_RS02970	COG1063	alcohol dehydrogenase
CK238_RS02975	COG5577	PFAM Coat F domain
CK238_RS02985	COG4585	Histidine kinase
CK238_RS02990	COG2197	response regulator
CK238_RS02995	COG2409	Drug exporters of the RND superfamily
CK238_RS03000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CK238_RS03005	COG0488	(ABC) transporter
CK238_RS03010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK238_RS03015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK238_RS03025	COG2814	Major facilitator Superfamily
CK238_RS03030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK238_RS03040	COG0730	response to heat
CK238_RS03045	COG0456	acetyltransferase
CK238_RS03050	COG4978	Transcriptional regulator
CK238_RS03050	COG0789	Transcriptional regulator
CK238_RS03055	COG0697	spore germination
CK238_RS03060	COG1051	belongs to the nudix hydrolase family
CK238_RS03065	COG2226	methyltransferase
CK238_RS03070	COG0473	3-isopropylmalate dehydrogenase activity
CK238_RS03075	COG1802	Transcriptional regulator
CK238_RS03080	COG1819	glycosyl
CK238_RS03095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK238_RS03100	COG1388	LysM domain
CK238_RS03105	COG2814	Major facilitator Superfamily
CK238_RS03110	COG2188	Transcriptional regulator
CK238_RS03115	COG2186	Transcriptional regulator
CK238_RS03120	COG2807	transmembrane transport
CK238_RS03125	COG2076	Multidrug Resistance protein
CK238_RS03130	COG2076	Multidrug Resistance protein
CK238_RS03135	COG1309	transcriptional regulator
CK238_RS03140	COG0531	amino acid
CK238_RS03150	COG3832	glyoxalase III activity
CK238_RS03155	COG0604	alcohol dehydrogenase
CK238_RS03165	COG2814	Major facilitator Superfamily
CK238_RS03205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CK238_RS03210	COG0802	atpase or kinase
CK238_RS03215	COG1214	PFAM Peptidase M22, glycoprotease
CK238_RS03220	COG0456	acetyltransferase
CK238_RS03225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CK238_RS03230	COG0488	(ABC) transporter
CK238_RS03245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CK238_RS03250	COG0805	protein transport
CK238_RS03260	COG1266	CAAX protease self-immunity
CK238_RS03275	COG0156	8-amino-7-oxononanoate synthase activity
CK238_RS03295	COG3403	YqcI/YcgG family
CK238_RS03310	COG2814	Major facilitator Superfamily
CK238_RS03315	COG0457	Tetratricopeptide repeat
CK238_RS03320	COG1063	alcohol dehydrogenase
CK238_RS03325	COG2211	Major facilitator Superfamily
CK238_RS03330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK238_RS03340	COG1842	Phage shock protein A
CK238_RS03345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CK238_RS03350	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CK238_RS03355	COG4260	virion core protein, lumpy skin disease virus
CK238_RS03360	COG2755	lipolytic protein G-D-S-L family
CK238_RS03360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CK238_RS03370	COG1595	DNA-templated transcription, initiation
CK238_RS03375	COG1063	alcohol dehydrogenase
CK238_RS03380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CK238_RS03385	COG0823	Involved in the tonB-independent uptake of proteins
CK238_RS03400	COG2132	Multicopper oxidase
CK238_RS03405	COG1113	amino acid transport
CK238_RS03410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CK238_RS03415	COG0714	Associated with various cellular activities
CK238_RS03420	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CK238_RS03425	COG1305	Transglutaminase-like
CK238_RS03435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CK238_RS03455	COG2211	Major facilitator Superfamily
CK238_RS03470	COG2252	PERMEase
CK238_RS03475	COG3064	Membrane
CK238_RS03495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CK238_RS03500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CK238_RS03505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CK238_RS03510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CK238_RS03515	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CK238_RS03530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CK238_RS03540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CK238_RS03545	COG0138	bifunctional purine biosynthesis protein purh
CK238_RS03550	COG0151	Belongs to the GarS family
CK238_RS03560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CK238_RS03565	COG1470	cell adhesion involved in biofilm formation
CK238_RS03570	COG4496	protein, YerC YecD
CK238_RS03575	COG0069	glutamate synthase activity
CK238_RS03590	COG0210	DNA helicase
CK238_RS03600	COG4851	CamS sex pheromone cAM373 precursor
CK238_RS03605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK238_RS03610	COG1285	pathogenesis
CK238_RS03615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK238_RS03635	COG1309	transcriptional regulator
CK238_RS03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK238_RS03645	COG1597	lipid kinase activity
CK238_RS03650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK238_RS03655	COG2197	response regulator
CK238_RS03665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS03675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK238_RS03685	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS03690	COG1131	(ABC) transporter
CK238_RS03730	COG5444	nuclease activity
CK238_RS03740	COG5444	nuclease activity
CK238_RS03770	COG3546	catalase activity
CK238_RS03775	COG0454	-acetyltransferase
CK238_RS03785	COG2323	membrane
CK238_RS03790	COG2329	Antibiotic biosynthesis monooxygenase
CK238_RS03795	COG0346	lactoylglutathione lyase activity
CK238_RS03805	COG1366	Belongs to the anti-sigma-factor antagonist family
CK238_RS03810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CK238_RS03815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CK238_RS03820	COG4208	sulfate ABC transporter
CK238_RS03830	COG5583	Uncharacterized small protein (DUF2292)
CK238_RS03835	COG0196	riboflavin kinase activity
CK238_RS03840	COG0670	Belongs to the BI1 family
CK238_RS03845	COG1846	Transcriptional regulator
CK238_RS03850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK238_RS03860	COG2124	cytochrome p450
CK238_RS03860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK238_RS03875	COG1131	(ABC) transporter
CK238_RS03890	COG1368	sulfuric ester hydrolase activity
CK238_RS03895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CK238_RS03900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK238_RS03905	COG1442	glycosyl transferase family 8
CK238_RS03910	COG1216	Glycosyl transferase, family 2
CK238_RS03915	COG1442	glycosyl transferase family 8
CK238_RS03920	COG2223	nitrite transmembrane transporter activity
CK238_RS03925	COG0531	amino acid
CK238_RS03930	COG1012	belongs to the aldehyde dehydrogenase family
CK238_RS03935	COG0840	transmembrane signaling receptor activity
CK238_RS03940	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS03945	COG0457	Tetratricopeptide repeat
CK238_RS03945	COG0463	Glycosyl transferase, family 2
CK238_RS03950	COG0488	(ABC) transporter
CK238_RS03955	COG0789	Transcriptional regulator
CK238_RS03960	COG2814	Major facilitator Superfamily
CK238_RS03965	COG0488	(ABC) transporter
CK238_RS03970	COG0513	Belongs to the DEAD box helicase family
CK238_RS03980	COG2130	NADP-dependent
CK238_RS03995	COG3866	Pectate lyase
CK238_RS04000	COG0471	metal ion transport
CK238_RS04020	COG3290	protein histidine kinase activity
CK238_RS04025	COG4565	transcriptional regulatory protein
CK238_RS04030	COG3181	Tripartite tricarboxylate transporter family receptor
CK238_RS04040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK238_RS04045	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CK238_RS04055	COG2258	MOSC domain
CK238_RS04075	COG0024	Methionine aminopeptidase
CK238_RS04080	COG1263	PTS System
CK238_RS04080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK238_RS04090	COG1368	sulfuric ester hydrolase activity
CK238_RS04100	COG0071	Belongs to the small heat shock protein (HSP20) family
CK238_RS04115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK238_RS04115	COG1263	PTS System
CK238_RS04120	COG0366	Alpha amylase catalytic
CK238_RS04125	COG2188	Transcriptional regulator
CK238_RS04130	COG0778	Nitroreductase
CK238_RS04145	COG0737	Belongs to the 5'-nucleotidase family
CK238_RS04150	COG0693	protein deglycase activity
CK238_RS04155	COG1609	Transcriptional regulator
CK238_RS04170	COG2814	Major facilitator Superfamily
CK238_RS04180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CK238_RS04185	COG4980	gas vesicle protein
CK238_RS04190	COG1295	ribonuclease BN
CK238_RS04195	COG0477	Major facilitator Superfamily
CK238_RS04200	COG0387	Pfam Sodium calcium exchanger
CK238_RS04210	COG0668	transmembrane transport
CK238_RS04215	COG0535	radical SAM domain protein
CK238_RS04225	COG0726	polysaccharide deacetylase
CK238_RS04230	COG2084	Dehydrogenase
CK238_RS04240	COG0598	Magnesium transport protein CorA
CK238_RS04245	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CK238_RS04250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK238_RS04270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK238_RS04275	COG4637	Psort location Cytoplasmic, score
CK238_RS04280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CK238_RS04285	COG0022	dehydrogenase e1 component
CK238_RS04290	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK238_RS04295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK238_RS04300	COG3284	Transcriptional regulator
CK238_RS04310	COG1486	melibiose metabolic process
CK238_RS04315	COG1737	Transcriptional regulator
CK238_RS04320	COG1263	PTS System
CK238_RS04320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK238_RS04325	COG1132	(ABC) transporter
CK238_RS04330	COG1132	(ABC) transporter
CK238_RS04340	COG2259	Doxx family
CK238_RS04345	COG2514	catechol 2,3-dioxygenase activity
CK238_RS04355	COG1695	Transcriptional regulator
CK238_RS04360	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK238_RS04370	COG0574	Belongs to the PEP-utilizing enzyme family
CK238_RS04370	COG3848	Pyruvate phosphate dikinase
CK238_RS04375	COG2732	(Barnase) inhibitor
CK238_RS04385	COG2814	Major facilitator Superfamily
CK238_RS04390	COG1846	Transcriptional regulator
CK238_RS04395	COG0392	lysyltransferase activity
CK238_RS04395	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CK238_RS04400	COG0384	phenazine biosynthesis protein PhzF
CK238_RS04405	COG0778	Nitroreductase
CK238_RS04420	COG1090	epimerase
CK238_RS04435	COG2814	Major facilitator Superfamily
CK238_RS04445	COG3591	Belongs to the peptidase S1B family
CK238_RS04460	COG3103	Sh3 type 3 domain protein
CK238_RS04465	COG5658	integral membrane protein
CK238_RS04470	COG0596	Alpha beta hydrolase
CK238_RS04475	COG0463	Glycosyl transferase, family 2
CK238_RS04480	COG4485	Bacterial membrane protein, YfhO
CK238_RS04485	COG1988	membrane-bound metal-dependent
CK238_RS04490	COG1194	a g-specific adenine glycosylase
CK238_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS04520	COG1132	(ABC) transporter
CK238_RS04525	COG4129	membrane
CK238_RS04535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK238_RS04540	COG0735	belongs to the Fur family
CK238_RS04700	COG5577	PFAM Coat F domain
CK238_RS04705	COG3340	Belongs to the peptidase S51 family
CK238_RS04715	COG0277	FAD linked oxidase domain protein
CK238_RS04725	COG0747	negative chemotaxis
CK238_RS04730	COG0601	transmembrane transport
CK238_RS04735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK238_RS04740	COG0444	Belongs to the ABC transporter superfamily
CK238_RS04745	COG4608	Belongs to the ABC transporter superfamily
CK238_RS04750	COG0753	catalase activity
CK238_RS04760	COG1116	anion transmembrane transporter activity
CK238_RS04765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK238_RS04770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK238_RS04795	COG1476	TRANSCRIPTIONal
CK238_RS04805	COG3382	B3 4 domain protein
CK238_RS04810	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CK238_RS04820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CK238_RS04825	COG0789	Transcriptional regulator
CK238_RS04830	COG1664	Polymer-forming cytoskeletal
CK238_RS04835	COG1664	Polymer-forming cytoskeletal
CK238_RS04845	COG2766	serine protein kinase
CK238_RS04860	COG1846	Transcriptional regulator
CK238_RS04865	COG1566	PFAM secretion protein HlyD family protein
CK238_RS04870	COG2814	Major facilitator Superfamily
CK238_RS04875	COG0655	NAD(P)H dehydrogenase (quinone) activity
CK238_RS04890	COG1725	Transcriptional regulator
CK238_RS04895	COG1131	(ABC) transporter
CK238_RS04900	COG1131	(ABC) transporter
CK238_RS04905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CK238_RS04910	COG1278	Cold shock
CK238_RS04920	COG1464	Belongs to the NlpA lipoprotein family
CK238_RS04925	COG3706	GGDEF domain
CK238_RS04930	COG1823	symporter activity
CK238_RS04950	COG5577	PFAM Coat F domain
CK238_RS04955	COG1525	nuclease
CK238_RS04955	COG0737	Belongs to the 5'-nucleotidase family
CK238_RS04955	COG4085	toxin activity
CK238_RS04960	COG3764	Sortase (surface protein transpeptidase)
CK238_RS04965	COG0564	pseudouridine synthase activity
CK238_RS04975	COG0517	IMP dehydrogenase activity
CK238_RS04980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK238_RS04985	COG3153	acetyltransferase
CK238_RS04985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK238_RS04990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CK238_RS04995	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CK238_RS05000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CK238_RS05010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CK238_RS05015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK238_RS05020	COG2203	Gaf domain
CK238_RS05020	COG4585	Histidine kinase
CK238_RS05025	COG2197	response regulator
CK238_RS05030	COG0431	NADPH-dependent FMN reductase
CK238_RS05045	COG0791	NLP P60 protein
CK238_RS05045	COG1388	LysM domain
CK238_RS05050	COG1959	2 iron, 2 sulfur cluster binding
CK238_RS05060	COG0668	transmembrane transport
CK238_RS05065	COG2719	SpoVR family
CK238_RS05070	COG1785	Belongs to the alkaline phosphatase family
CK238_RS05075	COG1388	LysM domain
CK238_RS05075	COG0791	NLP P60 protein
CK238_RS05080	COG0583	DNA-binding transcription factor activity
CK238_RS05085	COG0372	Belongs to the citrate synthase family
CK238_RS05090	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS05095	COG0531	amino acid
CK238_RS05100	COG0733	neurotransmitter:sodium symporter activity
CK238_RS05115	COG1595	DNA-templated transcription, initiation
CK238_RS05120	COG0204	Acyl-transferase
CK238_RS05125	COG1253	flavin adenine dinucleotide binding
CK238_RS05130	COG0789	Transcriptional regulator
CK238_RS05135	COG0436	Aminotransferase
CK238_RS05140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK238_RS05145	COG1253	flavin adenine dinucleotide binding
CK238_RS05150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CK238_RS05155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CK238_RS05160	COG0584	glycerophosphoryl diester phosphodiesterase
CK238_RS05170	COG0668	transmembrane transport
CK238_RS05175	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CK238_RS05180	COG0726	polysaccharide deacetylase
CK238_RS05185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK238_RS05190	COG3226	Transcriptional regulator
CK238_RS05200	COG0589	response to stress
CK238_RS05205	COG1132	(ABC) transporter
CK238_RS05210	COG1132	(ABC) transporter
CK238_RS05215	COG0702	epimerase
CK238_RS05235	COG0189	ligase activity
CK238_RS05240	COG0189	ligase activity
CK238_RS05255	COG4335	DNA alkylation repair
CK238_RS05260	COG0561	phosphatase activity
CK238_RS05265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK238_RS05275	COG0475	glutathione-regulated potassium exporter activity
CK238_RS05280	COG0490	domain, Protein
CK238_RS05290	COG1024	Enoyl-CoA hydratase
CK238_RS05300	COG4152	abc transporter atp-binding protein
CK238_RS05305	COG1668	transmembrane transport
CK238_RS05310	COG0420	3'-5' exonuclease activity
CK238_RS05315	COG4717	serine-type aminopeptidase activity
CK238_RS05330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK238_RS05370	COG4980	gas vesicle protein
CK238_RS05385	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CK238_RS05390	COG0537	adenosine 5'-monophosphoramidase activity
CK238_RS05395	COG1131	(ABC) transporter
CK238_RS05400	COG4473	ABC transporter
CK238_RS05410	COG1473	amidohydrolase
CK238_RS05415	COG3069	C4-dicarboxylate transmembrane transporter activity
CK238_RS05420	COG2329	Antibiotic biosynthesis monooxygenase
CK238_RS05425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK238_RS05435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CK238_RS05440	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CK238_RS05445	COG1309	transcriptional regulator
CK238_RS05450	COG1511	domain protein
CK238_RS05455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK238_RS05465	COG1363	Peptidase, m42
CK238_RS05470	COG1301	dicarboxylic acid transport
CK238_RS05480	COG1234	tRNA 3'-trailer cleavage
CK238_RS05485	COG0095	Lipoate-protein ligase
CK238_RS05490	COG0702	epimerase
CK238_RS05495	COG0318	PFAM AMP-dependent synthetase and ligase
CK238_RS05505	COG0501	Belongs to the peptidase M48B family
CK238_RS05510	COG1404	Belongs to the peptidase S8 family
CK238_RS05525	COG0406	alpha-ribazole phosphatase activity
CK238_RS05530	COG0183	Belongs to the thiolase family
CK238_RS05535	COG0318	PFAM AMP-dependent synthetase and ligase
CK238_RS05540	COG1268	BioY protein
CK238_RS05545	COG0840	transmembrane signaling receptor activity
CK238_RS05550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK238_RS05550	COG0723	plastoquinol--plastocyanin reductase activity
CK238_RS05555	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS05565	COG4903	ComK protein
CK238_RS05575	COG5646	InterPro IPR014922
CK238_RS05600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK238_RS05615	COG0398	Pfam SNARE associated Golgi protein
CK238_RS05620	COG0681	Belongs to the peptidase S26 family
CK238_RS05625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK238_RS05630	COG1846	Transcriptional regulator
CK238_RS05635	COG3180	Ammonia monooxygenase
CK238_RS05640	COG2814	Major facilitator Superfamily
CK238_RS05650	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CK238_RS05655	COG2323	membrane
CK238_RS05670	COG0420	3'-5' exonuclease activity
CK238_RS05675	COG0419	ATPase involved in DNA repair
CK238_RS05680	COG1403	HNH endonuclease
CK238_RS05720	COG0179	Fumarylacetoacetate (FAA) hydrolase
CK238_RS05735	COG0367	asparagine synthase
CK238_RS05740	COG1562	ergosterol biosynthetic process
CK238_RS05745	COG0534	Mate efflux family protein
CK238_RS05750	COG1917	Cupin 2, conserved barrel domain protein
CK238_RS05750	COG2207	Transcriptional regulator
CK238_RS05755	COG1609	Transcriptional regulator
CK238_RS05760	COG0673	inositol 2-dehydrogenase activity
CK238_RS05765	COG2318	DinB family
CK238_RS05770	COG1279	arginine transmembrane transporter activity
CK238_RS05775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK238_RS05780	COG1357	PFAM Pentapeptide repeats (8 copies)
CK238_RS05785	COG2153	protein acetylation
CK238_RS05790	COG0646	methionine synthase
CK238_RS05790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CK238_RS05800	COG2996	Protein conserved in bacteria
CK238_RS05805	COG1744	ABC transporter substrate-binding protein PnrA-like
CK238_RS05810	COG0840	transmembrane signaling receptor activity
CK238_RS05815	COG2124	cytochrome p450
CK238_RS05825	COG1307	EDD domain protein, DegV family
CK238_RS05830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK238_RS05845	COG0561	phosphatase activity
CK238_RS05850	COG1073	alpha beta
CK238_RS05855	COG2151	metal-sulfur cluster biosynthetic enzyme
CK238_RS05865	COG0277	FAD linked oxidase domain protein
CK238_RS05870	COG2271	Major facilitator Superfamily
CK238_RS05880	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CK238_RS05890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK238_RS05895	COG0505	Belongs to the CarA family
CK238_RS05900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CK238_RS05905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CK238_RS05925	COG2267	carboxylic ester hydrolase activity
CK238_RS05935	COG1744	ABC transporter substrate-binding protein PnrA-like
CK238_RS05950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK238_RS05955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK238_RS05960	COG5504	Zn-dependent protease
CK238_RS05965	COG0444	Belongs to the ABC transporter superfamily
CK238_RS05970	COG4608	Belongs to the ABC transporter superfamily
CK238_RS05980	COG0601	transmembrane transport
CK238_RS05985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK238_RS05995	COG0180	Tryptophanyl-tRNA synthetase
CK238_RS06000	COG4166	transmembrane transport
CK238_RS06005	COG0601	transmembrane transport
CK238_RS06010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK238_RS06015	COG0444	Belongs to the ABC transporter superfamily
CK238_RS06020	COG4608	Belongs to the ABC transporter superfamily
CK238_RS06030	COG0456	acetyltransferase
CK238_RS06035	COG1393	Belongs to the ArsC family
CK238_RS06040	COG0861	Integral membrane protein TerC family
CK238_RS06045	COG4862	establishment of competence for transformation
CK238_RS06050	COG4469	Competence protein
CK238_RS06055	COG1164	Oligoendopeptidase f
CK238_RS06060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CK238_RS06065	COG2346	COG2346, Truncated hemoglobins
CK238_RS06070	COG0741	lytic transglycosylase activity
CK238_RS06075	COG4116	CYTH
CK238_RS06085	COG2357	RelA SpoT domain protein
CK238_RS06090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK238_RS06095	COG0564	pseudouridine synthase activity
CK238_RS06105	COG0569	domain protein
CK238_RS06105	COG0475	glutathione-regulated potassium exporter activity
CK238_RS06110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CK238_RS06115	COG0352	thiamine-phosphate diphosphorylase activity
CK238_RS06120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK238_RS06125	COG2104	thiamine diphosphate biosynthetic process
CK238_RS06135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK238_RS06140	COG0351	phosphomethylpyrimidine kinase
CK238_RS06145	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CK238_RS06200	COG0210	DNA helicase
CK238_RS06220	COG1131	(ABC) transporter
CK238_RS06230	COG2153	protein acetylation
CK238_RS06240	COG2382	esterase
CK238_RS06245	COG0626	cystathionine gamma-synthase activity
CK238_RS06250	COG0626	cystathionine gamma-synthase activity
CK238_RS06260	COG0582	viral genome integration into host DNA
CK238_RS06360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CK238_RS06485	COG5444	nuclease activity
CK238_RS06505	COG0135	phosphoribosylanthranilate isomerase activity
CK238_RS06515	COG2367	Beta-lactamase
CK238_RS06520	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CK238_RS06525	COG0477	Major facilitator Superfamily
CK238_RS06530	COG1846	Transcriptional regulator
CK238_RS06540	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CK238_RS06545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK238_RS06550	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CK238_RS06555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK238_RS06555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK238_RS06560	COG1447	Phosphotransferase system cellobiose-specific component IIA
CK238_RS06570	COG1349	DNA-binding transcription factor activity
CK238_RS06590	COG1285	pathogenesis
CK238_RS06605	COG2205	protein histidine kinase activity
CK238_RS06615	COG3383	formate dehydrogenase (NAD+) activity
CK238_RS06620	COG2427	Protein of unknown function (DUF1641)
CK238_RS06625	COG2124	cytochrome p450
CK238_RS06630	COG1819	glycosyl
CK238_RS06640	COG1587	Uroporphyrinogen-III synthase
CK238_RS06645	COG0390	transport system, permease component
CK238_RS06650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK238_RS06655	COG0697	spore germination
CK238_RS06660	COG4297	protein containing double-stranded beta helix domain
CK238_RS06670	COG1252	NADH dehydrogenase
CK238_RS06685	COG1609	Transcriptional regulator
CK238_RS06690	COG0246	Mannitol dehydrogenase
CK238_RS06695	COG2721	sulfolactate sulfo-lyase activity
CK238_RS06700	COG0745	RESPONSE REGULATOR receiver
CK238_RS06705	COG2205	protein histidine kinase activity
CK238_RS06705	COG2770	Histidine kinase
CK238_RS06725	COG4585	Histidine kinase
CK238_RS06730	COG2197	response regulator
CK238_RS06755	COG0730	response to heat
CK238_RS06760	COG2318	DinB family
CK238_RS06765	COG0457	Tetratricopeptide repeat
CK238_RS06770	COG1388	LysM domain
CK238_RS06770	COG5632	N-Acetylmuramoyl-L-alanine amidase
CK238_RS06770	COG3409	Peptidoglycan-binding domain 1 protein
CK238_RS06780	COG4195	phage-related replication protein
CK238_RS06785	COG2856	Zn peptidase
CK238_RS06790	COG1396	sequence-specific DNA binding
CK238_RS06800	COG1522	sequence-specific DNA binding
CK238_RS06805	COG1484	DNA-dependent DNA replication
CK238_RS06820	COG1595	DNA-templated transcription, initiation
CK238_RS06825	COG4193	domain, Protein
CK238_RS06860	COG5632	N-Acetylmuramoyl-L-alanine amidase
CK238_RS06860	COG3409	Peptidoglycan-binding domain 1 protein
CK238_RS06875	COG0306	phosphate transporter
CK238_RS06880	COG1392	Phosphate transport regulator
CK238_RS06885	COG0531	amino acid
CK238_RS06890	COG0346	lactoylglutathione lyase activity
CK238_RS06895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CK238_RS06900	COG0463	Glycosyl transferase, family 2
CK238_RS06905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK238_RS06910	COG0477	Major facilitator Superfamily
CK238_RS06915	COG2362	D-Aminopeptidase
CK238_RS06920	COG0601	transmembrane transport
CK238_RS06925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK238_RS06930	COG0444	Belongs to the ABC transporter superfamily
CK238_RS06935	COG4166	transmembrane transport
CK238_RS06940	COG1619	proteins homologs of microcin C7 resistance protein MccF
CK238_RS06945	COG4948	Mandelate Racemase Muconate Lactonizing
CK238_RS06950	COG0791	NLP P60 protein
CK238_RS06955	COG4608	Belongs to the ABC transporter superfamily
CK238_RS06960	COG2706	6-phosphogluconolactonase activity
CK238_RS06965	COG1834	amidinotransferase
CK238_RS06970	COG1607	acyl-coa hydrolase
CK238_RS06975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK238_RS06980	COG2076	Multidrug Resistance protein
CK238_RS06985	COG2076	Multidrug Resistance protein
CK238_RS06990	COG0788	formyltetrahydrofolate deformylase activity
CK238_RS06995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CK238_RS07005	COG1764	response to oxidative stress
CK238_RS07010	COG1846	Transcriptional regulator
CK238_RS07015	COG1764	response to oxidative stress
CK238_RS07030	COG0463	Glycosyl transferase, family 2
CK238_RS07030	COG0457	Tetratricopeptide repeat
CK238_RS07040	COG2814	Major facilitator Superfamily
CK238_RS07045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK238_RS07055	COG1404	Belongs to the peptidase S8 family
CK238_RS07060	COG1366	Belongs to the anti-sigma-factor antagonist family
CK238_RS07065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CK238_RS07070	COG1122	ATPase activity
CK238_RS07075	COG4721	ABC-type cobalt transport system, permease component
CK238_RS07080	COG1388	LysM domain
CK238_RS07080	COG3858	chitin binding
CK238_RS07100	COG2239	Acts as a magnesium transporter
CK238_RS07105	COG0789	Transcriptional regulator
CK238_RS07120	COG1846	Transcriptional regulator
CK238_RS07125	COG0726	polysaccharide deacetylase
CK238_RS07130	COG3285	dna ligase
CK238_RS07130	COG1793	dna ligase
CK238_RS07135	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CK238_RS07140	COG0586	Pfam SNARE associated Golgi protein
CK238_RS07145	COG0861	Integral membrane protein TerC family
CK238_RS07150	COG1191	sigma factor activity
CK238_RS07175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK238_RS07180	COG2323	membrane
CK238_RS07190	COG3594	Acyltransferase
CK238_RS07195	COG5002	protein histidine kinase activity
CK238_RS07200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK238_RS07215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK238_RS07220	COG0436	Aminotransferase
CK238_RS07250	COG3852	Histidine kinase
CK238_RS07255	COG1846	Transcriptional regulator
CK238_RS07260	COG1360	Flagellar Motor Protein
CK238_RS07265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CK238_RS07270	COG0542	response to heat
CK238_RS07280	COG3949	Membrane
CK238_RS07295	COG0720	synthase
CK238_RS07300	COG0602	queuosine metabolic process
CK238_RS07305	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CK238_RS07315	COG4873	Protein conserved in bacteria
CK238_RS07325	COG3773	Cell wall hydrolase
CK238_RS07330	COG2244	polysaccharide biosynthetic process
CK238_RS07335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK238_RS07340	COG2217	Heavy metal translocating P-type atpase
CK238_RS07345	COG0006	proline dipeptidase activity
CK238_RS07350	COG1609	Transcriptional regulator
CK238_RS07355	COG3711	transcriptional antiterminator
CK238_RS07360	COG2190	(PTS) system
CK238_RS07360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK238_RS07360	COG1263	PTS System
CK238_RS07365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK238_RS07370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CK238_RS07380	COG1533	DNA photolyase activity
CK238_RS07385	COG0840	transmembrane signaling receptor activity
CK238_RS07390	COG2084	Dehydrogenase
CK238_RS07395	COG2340	Cysteine-rich secretory protein family
CK238_RS07400	COG0768	penicillin binding
CK238_RS07405	COG4191	Histidine kinase
CK238_RS07410	COG0436	Aminotransferase
CK238_RS07420	COG0835	chemotaxis
CK238_RS07420	COG0784	Response regulator, receiver
CK238_RS07430	COG2814	Major facilitator Superfamily
CK238_RS07435	COG1376	ErfK ybiS ycfS ynhG family protein
CK238_RS07440	COG1408	metallophosphoesterase
CK238_RS07445	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS07455	COG2200	EAL domain
CK238_RS07460	COG4703	Protein of unknown function (DUF1797)
CK238_RS07465	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CK238_RS07475	COG0517	IMP dehydrogenase activity
CK238_RS07480	COG0583	DNA-binding transcription factor activity
CK238_RS07485	COG0716	FMN binding
CK238_RS07495	COG0716	FMN binding
CK238_RS07515	COG0668	transmembrane transport
CK238_RS07520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK238_RS07540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK238_RS07545	COG0303	'Molybdopterin
CK238_RS07550	COG1763	Mo-molybdopterin cofactor biosynthetic process
CK238_RS07555	COG0314	molybdopterin synthase activity
CK238_RS07560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CK238_RS07570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK238_RS07575	COG1136	(ABC) transporter
CK238_RS07580	COG0577	efflux transmembrane transporter activity
CK238_RS07585	COG1349	DNA-binding transcription factor activity
CK238_RS07590	COG1105	Belongs to the carbohydrate kinase PfkB family
CK238_RS07595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK238_RS07595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK238_RS07595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK238_RS07600	COG0681	Belongs to the peptidase S26 family
CK238_RS07610	COG0488	(ABC) transporter
CK238_RS07615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CK238_RS07620	COG2309	aminopeptidase activity
CK238_RS07630	COG1077	Cell shape determining protein MreB Mrl
CK238_RS07640	COG2002	toxin-antitoxin pair type II binding
CK238_RS07645	COG3852	Histidine kinase
CK238_RS07650	COG2105	PFAM AIG2 family protein
CK238_RS07650	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CK238_RS07655	COG0569	domain protein
CK238_RS07665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CK238_RS07675	COG0561	phosphatase activity
CK238_RS07680	COG0242	peptide deformylase activity
CK238_RS07690	COG0497	DNA recombination
CK238_RS07705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS07705	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS07705	COG3321	synthase
CK238_RS07705	COG4221	oxidoreductase activity
CK238_RS07710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS07710	COG0300	oxidoreductase activity
CK238_RS07710	COG3321	synthase
CK238_RS07710	COG4221	oxidoreductase activity
CK238_RS07715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS07715	COG4221	oxidoreductase activity
CK238_RS07715	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS07715	COG3321	synthase
CK238_RS07720	COG3321	synthase
CK238_RS07720	COG4221	oxidoreductase activity
CK238_RS07720	COG0300	oxidoreductase activity
CK238_RS07720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS07725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS07725	COG0300	oxidoreductase activity
CK238_RS07725	COG3321	synthase
CK238_RS07725	COG4221	oxidoreductase activity
CK238_RS07730	COG0300	oxidoreductase activity
CK238_RS07730	COG3321	synthase
CK238_RS07730	COG4221	oxidoreductase activity
CK238_RS07730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS07735	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS07735	COG4221	oxidoreductase activity
CK238_RS07735	COG3321	synthase
CK238_RS07735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS07740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK238_RS07745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CK238_RS07750	COG0022	dehydrogenase e1 component
CK238_RS07755	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK238_RS07760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK238_RS07765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK238_RS07780	COG1982	Orn Lys Arg decarboxylase major
CK238_RS07805	COG0483	inositol monophosphate 1-phosphatase activity
CK238_RS07815	COG3227	Zinc metalloprotease (Elastase)
CK238_RS07830	COG1595	DNA-templated transcription, initiation
CK238_RS07850	COG1217	gtp-binding protein TYPA
CK238_RS07860	COG4896	Protein conserved in bacteria
CK238_RS07870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CK238_RS07875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CK238_RS07880	COG2066	Belongs to the glutaminase family
CK238_RS07890	COG0772	Belongs to the SEDS family
CK238_RS07895	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CK238_RS07910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CK238_RS07910	COG2010	Cytochrome c
CK238_RS07915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CK238_RS07920	COG1845	cytochrome c oxidase, subunit III
CK238_RS07925	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CK238_RS07930	COG3336	cytochrome c oxidase
CK238_RS07940	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CK238_RS07945	COG2340	Cysteine-rich secretory protein family
CK238_RS07960	COG3679	Belongs to the UPF0342 family
CK238_RS07975	COG0742	ribosomal rna small subunit methyltransferase
CK238_RS07985	COG3314	Sporulation integral membrane protein YlbJ
CK238_RS07990	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK238_RS07995	COG3480	Lon protease (S16) C-terminal proteolytic domain
CK238_RS08005	COG1399	metal-binding, possibly nucleic acid-binding protein
CK238_RS08025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CK238_RS08045	COG4839	cell division protein FtsL
CK238_RS08050	COG0768	penicillin binding
CK238_RS08055	COG0768	penicillin binding
CK238_RS08075	COG0772	Belongs to the SEDS family
CK238_RS08090	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CK238_RS08095	COG0849	cell division
CK238_RS08100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CK238_RS08105	COG1404	Belongs to the peptidase S8 family
CK238_RS08105	COG4412	M6 family metalloprotease domain protein
CK238_RS08115	COG1191	sigma factor activity
CK238_RS08120	COG1191	sigma factor activity
CK238_RS08125	COG1119	ATPase activity
CK238_RS08130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK238_RS08135	COG1873	PFAM PRC-barrel domain
CK238_RS08140	COG1496	oxidoreductase activity
CK238_RS08145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CK238_RS08155	COG0762	integral membrane protein
CK238_RS08160	COG2302	S4 RNA-binding domain
CK238_RS08165	COG3599	regulation of cell shape
CK238_RS08175	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CK238_RS08180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK238_RS08190	COG0564	pseudouridine synthase activity
CK238_RS08200	COG2233	PERMEase
CK238_RS08210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CK238_RS08215	COG0505	Belongs to the CarA family
CK238_RS08220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CK238_RS08235	COG0284	orotidine-5'-phosphate decarboxylase activity
CK238_RS08240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CK238_RS08250	COG0306	phosphate transporter
CK238_RS08265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK238_RS08270	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CK238_RS08275	COG1648	precorrin-2 dehydrogenase activity
CK238_RS08290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CK238_RS08295	COG1561	YicC-like family, N-terminal region
CK238_RS08305	COG0194	GDP metabolic process
CK238_RS08315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CK238_RS08320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CK238_RS08325	COG0242	peptide deformylase activity
CK238_RS08335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CK238_RS08335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CK238_RS08345	COG0631	protein serine/threonine phosphatase activity
CK238_RS08350	COG2815	serine threonine protein kinase
CK238_RS08350	COG0515	serine threonine protein kinase
CK238_RS08360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CK238_RS08365	COG1564	THIamine pyrophosphokinase
CK238_RS08380	COG1302	Protein conserved in bacteria
CK238_RS08385	COG1461	Dihydroxyacetone kinase
CK238_RS08390	COG1760	l-serine dehydratase
CK238_RS08395	COG1760	l-serine dehydratase
CK238_RS08400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CK238_RS08415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CK238_RS08420	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS08435	COG1196	nuclear chromosome segregation
CK238_RS08440	COG0552	protein localization to endoplasmic reticulum
CK238_RS08455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CK238_RS08465	COG1837	Belongs to the UPF0109 family
CK238_RS08490	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CK238_RS08505	COG2257	FlhB HrpN YscU SpaS Family
CK238_RS08515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CK238_RS08520	COG0758	DNA mediated transformation
CK238_RS08525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK238_RS08535	COG4974	Belongs to the 'phage' integrase family
CK238_RS08555	COG1815	bacterial-type flagellum-dependent cell motility
CK238_RS08560	COG1558	bacterial-type flagellum-dependent cell motility
CK238_RS08565	COG1677	Flagellar hook-basal body complex protein FliE
CK238_RS08570	COG1766	The M ring may be actively involved in energy transduction
CK238_RS08575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK238_RS08580	COG1317	bacterial-type flagellum organization
CK238_RS08585	COG1157	protein secretion by the type III secretion system
CK238_RS08590	COG2882	bacterial-type flagellum organization
CK238_RS08595	COG3334	PFAM MgtE intracellular
CK238_RS08600	COG3144	bacterial-type flagellum assembly
CK238_RS08605	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CK238_RS08610	COG4786	Flagellar basal body rod
CK238_RS08615	COG1582	Flagellar protein (FlbD)
CK238_RS08620	COG1580	Controls the rotational direction of flagella during chemotaxis
CK238_RS08625	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK238_RS08630	COG1776	CheC inhibitor of MCP methylation
CK238_RS08630	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK238_RS08635	COG2201	protein-glutamate methylesterase activity
CK238_RS08640	COG3190	flagellar
CK238_RS08645	COG1338	Plays a role in the flagellum-specific transport system
CK238_RS08650	COG1987	bacterial-type flagellum assembly
CK238_RS08655	COG1684	flagellar biosynthetic protein fliR
CK238_RS08660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CK238_RS08665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CK238_RS08670	COG1419	protein localization to endoplasmic reticulum
CK238_RS08675	COG0455	bacterial-type flagellum organization
CK238_RS08680	COG2201	protein-glutamate methylesterase activity
CK238_RS08685	COG2198	Histidine kinase
CK238_RS08685	COG0643	Histidine kinase
CK238_RS08690	COG0835	chemotaxis
CK238_RS08695	COG1776	CheC inhibitor of MCP methylation
CK238_RS08705	COG1191	sigma factor activity
CK238_RS08735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CK238_RS08740	COG4589	Belongs to the CDS family
CK238_RS08750	COG0750	zinc metalloprotease
CK238_RS08760	COG2176	DNA-directed DNA polymerase activity
CK238_RS08770	COG0195	Participates in both transcription termination and antitermination
CK238_RS08775	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CK238_RS08780	COG1358	cellular component organization or biogenesis
CK238_RS08790	COG1550	Protein conserved in bacteria
CK238_RS08805	COG0196	riboflavin kinase activity
CK238_RS08820	COG0726	polysaccharide deacetylase
CK238_RS08825	COG0612	Peptidase, M16
CK238_RS08830	COG1873	PFAM PRC-barrel domain
CK238_RS08835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK238_RS08840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CK238_RS08845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CK238_RS08850	COG0527	aspartate kinase activity
CK238_RS08860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CK238_RS08865	COG0740	serine-type endopeptidase activity
CK238_RS08875	COG1674	ftsk spoiiie
CK238_RS08875	COG4980	gas vesicle protein
CK238_RS08880	COG2188	Transcriptional regulator
CK238_RS08885	COG2814	Major facilitator Superfamily
CK238_RS08890	COG1846	Transcriptional regulator
CK238_RS08895	COG1033	growth of symbiont in host cell
CK238_RS08895	COG2409	Drug exporters of the RND superfamily
CK238_RS08900	COG0612	Peptidase, M16
CK238_RS08905	COG0612	Peptidase, M16
CK238_RS08910	COG0300	oxidoreductase activity
CK238_RS08925	COG1426	Protein conserved in bacteria
CK238_RS08930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CK238_RS08945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK238_RS08955	COG1692	metallophosphoesterase
CK238_RS08960	COG2359	stage V sporulation protein S
CK238_RS08980	COG4550	Control of competence regulator ComK, YlbF/YmcA
CK238_RS09045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS09050	COG3425	synthase
CK238_RS09055	COG1024	Enoyl-CoA hydratase
CK238_RS09065	COG4221	oxidoreductase activity
CK238_RS09065	COG3321	synthase
CK238_RS09065	COG0300	oxidoreductase activity
CK238_RS09065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS09080	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS09080	COG3321	synthase
CK238_RS09080	COG4221	oxidoreductase activity
CK238_RS09080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS09090	COG2124	cytochrome p450
CK238_RS09095	COG3209	COG3209 Rhs family protein
CK238_RS09100	COG3619	membrane
CK238_RS09110	COG1404	Belongs to the peptidase S8 family
CK238_RS09120	COG4195	phage-related replication protein
CK238_RS09125	COG1764	response to oxidative stress
CK238_RS09135	COG2076	Multidrug Resistance protein
CK238_RS09175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK238_RS09180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK238_RS09185	COG4112	unkown
CK238_RS09190	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK238_RS09200	COG0464	growth
CK238_RS09205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CK238_RS09210	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CK238_RS09215	COG0789	Transcriptional regulator
CK238_RS09220	COG0174	glutamine synthetase
CK238_RS09255	COG2211	Major facilitator Superfamily
CK238_RS09260	COG3507	Belongs to the glycosyl hydrolase 43 family
CK238_RS09275	COG1070	Carbohydrate kinase
CK238_RS09280	COG3848	Pyruvate phosphate dikinase
CK238_RS09280	COG0574	Belongs to the PEP-utilizing enzyme family
CK238_RS09305	COG2378	regulation of single-species biofilm formation
CK238_RS09310	COG2318	DinB family
CK238_RS09315	COG1064	alcohol dehydrogenase
CK238_RS09345	COG5444	nuclease activity
CK238_RS09405	COG3397	chitin binding
CK238_RS09425	COG5434	Belongs to the glycosyl hydrolase 28 family
CK238_RS09435	COG0756	dUTP diphosphatase activity
CK238_RS09440	COG4195	phage-related replication protein
CK238_RS09470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CK238_RS09480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CK238_RS09500	COG0785	Cytochrome C biogenesis protein
CK238_RS09505	COG2201	protein-glutamate methylesterase activity
CK238_RS09510	COG4846	Membrane protein involved in cytochrome C biogenesis
CK238_RS09520	COG0071	Belongs to the small heat shock protein (HSP20) family
CK238_RS09535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CK238_RS09540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK238_RS09560	COG0824	Thioesterase
CK238_RS09570	COG4841	protein insertion into membrane
CK238_RS09580	COG1832	CoA-binding protein
CK238_RS09585	COG0187	DNA topoisomerase II activity
CK238_RS09590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CK238_RS09600	COG1115	amino acid carrier protein
CK238_RS09615	COG1063	alcohol dehydrogenase
CK238_RS09620	COG0800	Aldolase
CK238_RS09625	COG1312	Catalyzes the dehydration of D-mannonate
CK238_RS09630	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS09635	COG1609	Transcriptional regulator
CK238_RS09640	COG2271	Major facilitator Superfamily
CK238_RS09685	COG2205	protein histidine kinase activity
CK238_RS09690	COG0745	RESPONSE REGULATOR receiver
CK238_RS09700	COG3507	Belongs to the glycosyl hydrolase 43 family
CK238_RS09725	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS09730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK238_RS09735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CK238_RS09740	COG2610	gluconate transmembrane transporter activity
CK238_RS09745	COG2124	cytochrome p450
CK238_RS09765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CK238_RS09775	COG2246	polysaccharide biosynthetic process
CK238_RS09780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CK238_RS09785	COG0586	Pfam SNARE associated Golgi protein
CK238_RS09790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CK238_RS09795	COG1024	Enoyl-CoA hydratase
CK238_RS09800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CK238_RS09805	COG0511	ligase activity, forming carbon-carbon bonds
CK238_RS09810	COG0439	Biotin carboxylase
CK238_RS09815	COG0318	PFAM AMP-dependent synthetase and ligase
CK238_RS09820	COG1960	acyl-CoA dehydrogenase activity
CK238_RS09825	COG1649	PFAM Uncharacterised BCR, COG1649
CK238_RS09835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS09835	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CK238_RS09845	COG2027	D-alanyl-D-alanine carboxypeptidase
CK238_RS09850	COG2017	converts alpha-aldose to the beta-anomer
CK238_RS09855	COG0534	Mate efflux family protein
CK238_RS09870	COG0582	viral genome integration into host DNA
CK238_RS09875	COG0166	Belongs to the GPI family
CK238_RS09880	COG0405	Gamma-glutamyltransferase
CK238_RS09890	COG0640	Transcriptional regulator
CK238_RS09895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CK238_RS09905	COG0604	alcohol dehydrogenase
CK238_RS09915	COG0493	'glutamate synthase
CK238_RS09920	COG0070	glutamate synthase
CK238_RS09920	COG0067	glutamate synthase
CK238_RS09920	COG0069	glutamate synthase activity
CK238_RS09925	COG0583	DNA-binding transcription factor activity
CK238_RS09930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CK238_RS09945	COG0300	oxidoreductase activity
CK238_RS09950	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CK238_RS09960	COG2814	Major facilitator Superfamily
CK238_RS09965	COG1070	Carbohydrate kinase
CK238_RS09970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK238_RS09975	COG0243	molybdopterin cofactor binding
CK238_RS10005	COG5444	nuclease activity
CK238_RS10010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK238_RS10015	COG0662	Cupin 2, conserved barrel domain protein
CK238_RS10015	COG2207	Transcriptional regulator
CK238_RS10020	COG1309	transcriptional regulator
CK238_RS10025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK238_RS10035	COG0640	Transcriptional regulator
CK238_RS10040	COG0741	lytic transglycosylase activity
CK238_RS10045	COG2322	membrane
CK238_RS10060	COG1619	proteins homologs of microcin C7 resistance protein MccF
CK238_RS10070	COG1388	LysM domain
CK238_RS10070	COG3584	3D domain protein
CK238_RS10075	COG0514	ATP-dependent DNA helicase (RecQ)
CK238_RS10085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CK238_RS10090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK238_RS10105	COG0071	Belongs to the small heat shock protein (HSP20) family
CK238_RS10135	COG1012	belongs to the aldehyde dehydrogenase family
CK238_RS10140	COG1657	PFAM Prenyltransferase squalene oxidase
CK238_RS10145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CK238_RS10150	COG0733	neurotransmitter:sodium symporter activity
CK238_RS10155	COG0385	Bile acid
CK238_RS10160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK238_RS10165	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK238_RS10175	COG4548	von Willebrand factor, type A
CK238_RS10180	COG0714	Associated with various cellular activities
CK238_RS10185	COG2032	superoxide dismutase activity
CK238_RS10190	COG1388	LysM domain
CK238_RS10190	COG0791	NLP P60 protein
CK238_RS10195	COG1819	glycosyl
CK238_RS10200	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CK238_RS10205	COG0534	Mate efflux family protein
CK238_RS10210	COG1366	Belongs to the anti-sigma-factor antagonist family
CK238_RS10215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CK238_RS10220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CK238_RS10230	COG2962	Rard protein
CK238_RS10245	COG1942	4-Oxalocrotonate Tautomerase
CK238_RS10255	COG1733	regulation of RNA biosynthetic process
CK238_RS10260	COG0778	Nitroreductase
CK238_RS10265	COG0400	carboxylic ester hydrolase activity
CK238_RS10270	COG0346	lactoylglutathione lyase activity
CK238_RS10280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK238_RS10290	COG2723	6-phospho-beta-galactosidase activity
CK238_RS10295	COG2188	Transcriptional regulator
CK238_RS10300	COG3409	Peptidoglycan-binding domain 1 protein
CK238_RS10300	COG0793	Belongs to the peptidase S41A family
CK238_RS10305	COG2226	methyltransferase
CK238_RS10315	COG1876	peptidase activity
CK238_RS10335	COG0671	phosphoesterase, PA-phosphatase related
CK238_RS10365	COG1509	lysine 2,3-aminomutase activity
CK238_RS10370	COG0456	acetyltransferase
CK238_RS10375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK238_RS10380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK238_RS10385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CK238_RS10390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CK238_RS10400	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CK238_RS10410	COG0456	acetyltransferase
CK238_RS10415	COG0463	Glycosyl transferase, family 2
CK238_RS10430	COG4641	Protein conserved in bacteria
CK238_RS10475	COG0457	Tetratricopeptide repeat
CK238_RS10485	COG3391	amine dehydrogenase activity
CK238_RS10505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK238_RS10520	COG5444	nuclease activity
CK238_RS10525	COG4282	regulation of fungal-type cell wall biogenesis
CK238_RS10530	COG1525	nuclease
CK238_RS10550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CK238_RS10570	COG1846	Transcriptional regulator
CK238_RS10575	COG4698	Protein conserved in bacteria
CK238_RS10580	COG2755	lipolytic protein G-D-S-L family
CK238_RS10585	COG1999	signal sequence binding
CK238_RS10595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CK238_RS10600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CK238_RS10605	COG1272	protein, Hemolysin III
CK238_RS10610	COG0204	Acyl-transferase
CK238_RS10615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CK238_RS10630	COG2521	methyltransferase
CK238_RS10630	COG2136	Putative SAM-dependent methyltransferase
CK238_RS10645	COG1413	lyase activity
CK238_RS10650	COG1418	mRNA catabolic process
CK238_RS10655	COG0386	Belongs to the glutathione peroxidase family
CK238_RS10665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CK238_RS10670	COG1278	Cold shock
CK238_RS10690	COG0328	RNA-DNA hybrid ribonuclease activity
CK238_RS10695	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CK238_RS10700	COG0328	RNA-DNA hybrid ribonuclease activity
CK238_RS10710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK238_RS10725	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CK238_RS10755	COG1335	isochorismatase
CK238_RS10765	COG2233	PERMEase
CK238_RS10775	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CK238_RS10780	COG1199	ATP-dependent helicase activity
CK238_RS10795	COG0116	Belongs to the methyltransferase superfamily
CK238_RS10820	COG3359	exonuclease
CK238_RS10825	COG1205	dead DEAH box helicase
CK238_RS10825	COG1111	helicase
CK238_RS10830	COG2190	(PTS) system
CK238_RS10835	COG0071	Belongs to the small heat shock protein (HSP20) family
CK238_RS10875	COG4499	WXG100 protein secretion system (Wss), protein YukC
CK238_RS10875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK238_RS10885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CK238_RS10890	COG3935	DnaD domain protein
CK238_RS10900	COG0436	Aminotransferase
CK238_RS10905	COG5353	protein conserved in bacteria
CK238_RS10915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK238_RS10915	COG1199	ATP-dependent helicase activity
CK238_RS10945	COG0438	transferase activity, transferring glycosyl groups
CK238_RS10950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CK238_RS10965	COG1694	Mazg nucleotide pyrophosphohydrolase
CK238_RS10970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK238_RS10975	COG2140	Oxalate decarboxylase
CK238_RS10985	COG4347	Protein of unknown function (DUF1405)
CK238_RS10990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CK238_RS10990	COG2010	Cytochrome c
CK238_RS10995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CK238_RS11000	COG0723	plastoquinol--plastocyanin reductase activity
CK238_RS11015	COG0457	Tetratricopeptide repeat
CK238_RS11025	COG0287	Prephenate dehydrogenase
CK238_RS11060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK238_RS11065	COG4401	Chorismate mutase type I
CK238_RS11080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CK238_RS11085	COG0105	UTP biosynthetic process
CK238_RS11090	COG0142	geranyltranstransferase activity
CK238_RS11100	COG0142	geranyltranstransferase activity
CK238_RS11115	COG0776	regulation of translation
CK238_RS11120	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CK238_RS11160	COG0539	negative regulation of cytoplasmic translation
CK238_RS11170	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CK238_RS11175	COG2959	enzyme of heme biosynthesis
CK238_RS11180	COG3773	Cell wall hydrolase
CK238_RS11180	COG3409	Peptidoglycan-binding domain 1 protein
CK238_RS11185	COG2339	peptidase activity
CK238_RS11190	COG0492	ferredoxin-NADP+ reductase activity
CK238_RS11195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CK238_RS11200	COG4862	establishment of competence for transformation
CK238_RS11205	COG1408	metallophosphoesterase
CK238_RS11215	COG1388	LysM domain
CK238_RS11220	COG1266	CAAX protease self-immunity
CK238_RS11225	COG0514	ATP-dependent DNA helicase (RecQ)
CK238_RS11230	COG4955	Helix-turn-helix domain
CK238_RS11235	COG1141	Ferredoxin
CK238_RS11240	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CK238_RS11245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK238_RS11255	COG1595	DNA-templated transcription, initiation
CK238_RS11260	COG5002	protein histidine kinase activity
CK238_RS11265	COG0745	RESPONSE REGULATOR receiver
CK238_RS11270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK238_RS11275	COG1333	cytochrome c biogenesis protein
CK238_RS11280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK238_RS11285	COG1187	pseudouridine synthase activity
CK238_RS11290	COG0700	Nucleoside recognition
CK238_RS11295	COG2715	membrane protein required for spore maturation
CK238_RS11300	COG1686	Belongs to the peptidase S11 family
CK238_RS11325	COG1547	Domain of unknown function (DUF309)
CK238_RS11335	COG0456	acetyltransferase
CK238_RS11350	COG0307	riboflavin synthase, alpha
CK238_RS11355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK238_RS11355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK238_RS11365	COG0681	Belongs to the peptidase S26 family
CK238_RS11375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CK238_RS11380	COG4086	secreted protein
CK238_RS11385	COG0019	diaminopimelate decarboxylase activity
CK238_RS11390	COG0697	spore germination
CK238_RS11405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK238_RS11425	COG1191	sigma factor activity
CK238_RS11435	COG1366	Belongs to the anti-sigma-factor antagonist family
CK238_RS11440	COG1686	Belongs to the peptidase S11 family
CK238_RS11445	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CK238_RS11450	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CK238_RS11455	COG4974	Belongs to the 'phage' integrase family
CK238_RS11465	COG0735	belongs to the Fur family
CK238_RS11470	COG1300	Membrane
CK238_RS11485	COG0281	malic enzyme
CK238_RS11490	COG1757	Na H antiporter
CK238_RS11495	COG1027	Aspartate ammonia-lyase
CK238_RS11500	COG0252	asparaginase activity
CK238_RS11505	COG1396	sequence-specific DNA binding
CK238_RS11510	COG1379	DNA repair
CK238_RS11515	COG0494	nUDIX hydrolase
CK238_RS11525	COG0667	Aldo Keto reductase
CK238_RS11535	COG1073	alpha beta
CK238_RS11545	COG4918	Iron-sulphur cluster biosynthesis
CK238_RS11550	COG0456	acetyltransferase
CK238_RS11550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CK238_RS11555	COG2329	Antibiotic biosynthesis monooxygenase
CK238_RS11560	COG0456	acetyltransferase
CK238_RS11565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK238_RS11580	COG0628	permease
CK238_RS11590	COG0346	lactoylglutathione lyase activity
CK238_RS11600	COG3048	D-serine ammonia-lyase activity
CK238_RS11610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK238_RS11615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CK238_RS11620	COG1024	Enoyl-CoA hydratase
CK238_RS11625	COG3425	synthase
CK238_RS11630	COG2124	cytochrome p450
CK238_RS11635	COG3321	synthase
CK238_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS11635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS11635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK238_RS11635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS11640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS11640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS11640	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS11640	COG3321	synthase
CK238_RS11640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK238_RS11645	COG0300	oxidoreductase activity
CK238_RS11645	COG0318	PFAM AMP-dependent synthetase and ligase
CK238_RS11645	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS11645	COG3321	synthase
CK238_RS11645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS11650	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS11650	COG3321	synthase
CK238_RS11650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS11650	COG0318	PFAM AMP-dependent synthetase and ligase
CK238_RS11650	COG0300	oxidoreductase activity
CK238_RS11655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS11655	COG3321	synthase
CK238_RS11655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS11655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK238_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS11660	COG3321	synthase
CK238_RS11660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS11660	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS11660	COG0300	oxidoreductase activity
CK238_RS11660	COG0318	PFAM AMP-dependent synthetase and ligase
CK238_RS11665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK238_RS11665	COG3321	synthase
CK238_RS11665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK238_RS11665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS11665	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS11670	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS11675	COG0318	PFAM AMP-dependent synthetase and ligase
CK238_RS11690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CK238_RS11690	COG2070	2-Nitropropane dioxygenase
CK238_RS11695	COG0250	Participates in transcription elongation, termination and antitermination
CK238_RS11720	COG0596	Alpha beta hydrolase
CK238_RS11735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CK238_RS11740	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CK238_RS11755	COG0706	membrane insertase activity
CK238_RS11760	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK238_RS11765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CK238_RS11770	COG0346	lactoylglutathione lyase activity
CK238_RS11775	COG1376	ErfK ybiS ycfS ynhG family protein
CK238_RS11780	COG4129	membrane
CK238_RS11785	COG1126	abc transporter atp-binding protein
CK238_RS11790	COG0765	amino acid transport
CK238_RS11795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK238_RS11805	COG1597	lipid kinase activity
CK238_RS11810	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK238_RS11815	COG0022	dehydrogenase e1 component
CK238_RS11820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CK238_RS11825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK238_RS11830	COG3426	butyrate kinase activity
CK238_RS11835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CK238_RS11840	COG0280	phosphate acetyltransferase
CK238_RS11845	COG3290	protein histidine kinase activity
CK238_RS11845	COG3829	transcription factor binding
CK238_RS11855	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CK238_RS11860	COG2079	MmgE PrpD family protein
CK238_RS11865	COG0372	Belongs to the citrate synthase family
CK238_RS11875	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK238_RS11880	COG0183	Belongs to the thiolase family
CK238_RS11885	COG0584	glycerophosphoryl diester phosphodiesterase
CK238_RS11890	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK238_RS11910	COG1902	pentaerythritol trinitrate reductase activity
CK238_RS11925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK238_RS11930	COG0745	RESPONSE REGULATOR receiver
CK238_RS11935	COG0750	zinc metalloprotease
CK238_RS11940	COG0497	DNA recombination
CK238_RS11950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CK238_RS11960	COG0142	geranyltranstransferase activity
CK238_RS11970	COG1570	exodeoxyribonuclease VII activity
CK238_RS11985	COG1302	Protein conserved in bacteria
CK238_RS11990	COG0439	Biotin carboxylase
CK238_RS11995	COG0511	ligase activity, forming carbon-carbon bonds
CK238_RS12035	COG3854	ATPases associated with a variety of cellular activities
CK238_RS12050	COG0006	proline dipeptidase activity
CK238_RS12060	COG3872	metal-dependent enzyme
CK238_RS12070	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK238_RS12085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK238_RS12105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CK238_RS12120	COG1396	sequence-specific DNA binding
CK238_RS12130	COG0681	Belongs to the peptidase S26 family
CK238_RS12155	COG4940	Competence protein ComGF
CK238_RS12165	COG4970	Tfp pilus assembly protein FimT
CK238_RS12170	COG4537	Required for transformation and DNA binding
CK238_RS12175	COG1459	type II secretion system
CK238_RS12180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK238_RS12185	COG0598	Magnesium transport protein CorA
CK238_RS12190	COG1253	flavin adenine dinucleotide binding
CK238_RS12195	COG1366	Belongs to the anti-sigma-factor antagonist family
CK238_RS12205	COG1393	Belongs to the ArsC family
CK238_RS12215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK238_RS12225	COG0011	TIGRFAM Protein of
CK238_RS12235	COG2866	Carboxypeptidase
CK238_RS12240	COG1940	carbohydrate kinase activity
CK238_RS12245	COG4483	Protein conserved in bacteria
CK238_RS12250	COG1757	Na H antiporter
CK238_RS12260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CK238_RS12275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CK238_RS12280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK238_RS12285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK238_RS12290	COG0581	inorganic phosphate transmembrane transporter activity
CK238_RS12295	COG0573	inorganic phosphate transmembrane transporter activity
CK238_RS12300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK238_RS12305	COG0768	penicillin binding
CK238_RS12310	COG0477	Major facilitator Superfamily
CK238_RS12315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CK238_RS12320	COG2839	Protein conserved in bacteria
CK238_RS12325	COG5521	maltodextrose utilization protein MalA
CK238_RS12330	COG1388	LysM domain
CK238_RS12340	COG4709	membrane
CK238_RS12345	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CK238_RS12350	COG0735	belongs to the Fur family
CK238_RS12355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK238_RS12370	COG0513	Belongs to the DEAD box helicase family
CK238_RS12385	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK238_RS12390	COG2384	SAM-dependent methyltransferase
CK238_RS12395	COG2010	Cytochrome c
CK238_RS12400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CK238_RS12405	COG0358	DNA primase activity
CK238_RS12420	COG0517	IMP dehydrogenase activity
CK238_RS12425	COG0751	glycine-tRNA ligase activity
CK238_RS12445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CK238_RS12450	COG0295	cytidine deaminase activity
CK238_RS12455	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CK238_RS12465	COG1480	7TM receptor with intracellular HD hydrolase
CK238_RS12470	COG1702	phosphate starvation-inducible protein PhoH
CK238_RS12475	COG0561	phosphatase activity
CK238_RS12490	COG4864	UPF0365 protein
CK238_RS12495	COG1030	water channel activity
CK238_RS12500	COG1610	YqeY-like protein
CK238_RS12510	COG1283	sodium-dependent phosphate transmembrane transporter activity
CK238_RS12515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CK238_RS12520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CK238_RS12550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK238_RS12565	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK238_RS12580	COG1466	dna polymerase III delta subunit
CK238_RS12590	COG0658	competence protein
CK238_RS12590	COG2333	competence protein COMEC
CK238_RS12595	COG2131	deaminase
CK238_RS12600	COG1596	polysaccharide export
CK238_RS12600	COG1555	photosystem II stabilization
CK238_RS12605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CK238_RS12610	COG2226	methyltransferase
CK238_RS12615	COG0799	negative regulation of ribosome biogenesis
CK238_RS12620	COG1713	HD superfamily hydrolase involved in NAD metabolism
CK238_RS12630	COG1534	Rna-binding protein
CK238_RS12635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CK238_RS12640	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CK238_RS12645	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CK238_RS12655	COG2755	lipolytic protein G-D-S-L family
CK238_RS12665	COG0398	Pfam SNARE associated Golgi protein
CK238_RS12690	COG1794	racemase activity, acting on amino acids and derivatives
CK238_RS12705	COG1733	regulation of RNA biosynthetic process
CK238_RS12710	COG0656	L-ascorbic acid biosynthetic process
CK238_RS12740	COG5444	nuclease activity
CK238_RS12745	COG4282	regulation of fungal-type cell wall biogenesis
CK238_RS12765	COG0583	DNA-binding transcription factor activity
CK238_RS12780	COG0642	Histidine kinase
CK238_RS12780	COG5002	protein histidine kinase activity
CK238_RS12785	COG0745	RESPONSE REGULATOR receiver
CK238_RS12790	COG2311	Membrane
CK238_RS12795	COG0454	-acetyltransferase
CK238_RS12800	COG0563	adenylate kinase activity
CK238_RS12810	COG2814	Major facilitator Superfamily
CK238_RS12830	COG5444	nuclease activity
CK238_RS12865	COG0456	acetyltransferase
CK238_RS12870	COG2318	DinB family
CK238_RS12880	COG0561	phosphatase activity
CK238_RS12885	COG0561	phosphatase activity
CK238_RS12895	COG1482	cell wall glycoprotein biosynthetic process
CK238_RS12900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK238_RS12900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK238_RS12900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK238_RS12905	COG3711	transcriptional antiterminator
CK238_RS12905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK238_RS12915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CK238_RS12920	COG0583	DNA-binding transcription factor activity
CK238_RS12925	COG2814	Major facilitator Superfamily
CK238_RS12930	COG2124	cytochrome p450
CK238_RS12930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK238_RS12935	COG1309	transcriptional regulator
CK238_RS12940	COG2226	methyltransferase
CK238_RS12955	COG2116	formate transmembrane transporter activity
CK238_RS12960	COG5609	conserved protein (DUF2294)
CK238_RS12965	COG3383	formate dehydrogenase (NAD+) activity
CK238_RS12970	COG2427	Protein of unknown function (DUF1641)
CK238_RS12980	COG0626	cystathionine gamma-synthase activity
CK238_RS12985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK238_RS13010	COG0768	penicillin binding
CK238_RS13035	COG5632	N-Acetylmuramoyl-L-alanine amidase
CK238_RS13035	COG3409	Peptidoglycan-binding domain 1 protein
CK238_RS13040	COG4824	toxin secretion phage lysis holin
CK238_RS13060	COG5434	Belongs to the glycosyl hydrolase 28 family
CK238_RS13065	COG1705	Flagellar rod assembly protein muramidase FlgJ
CK238_RS13075	COG3953	SLT domain
CK238_RS13075	COG5280	Phage tail tape measure protein TP901
CK238_RS13160	COG0582	viral genome integration into host DNA
CK238_RS13165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CK238_RS13260	COG1396	sequence-specific DNA binding
CK238_RS13285	COG0826	peptidase U32
CK238_RS13290	COG0826	peptidase U32
CK238_RS13295	COG4122	O-methyltransferase activity
CK238_RS13300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CK238_RS13315	COG4472	Bacterial protein of unknown function (DUF965)
CK238_RS13325	COG0628	permease
CK238_RS13330	COG1126	abc transporter atp-binding protein
CK238_RS13335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK238_RS13340	COG0765	amino acid transport
CK238_RS13345	COG0765	amino acid transport
CK238_RS13360	COG3881	PFAM PRC-barrel domain
CK238_RS13365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK238_RS13370	COG0457	Tetratricopeptide repeat
CK238_RS13380	COG1104	cysteine desulfurase activity
CK238_RS13385	COG1959	2 iron, 2 sulfur cluster binding
CK238_RS13390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CK238_RS13395	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CK238_RS13415	COG3103	Sh3 type 3 domain protein
CK238_RS13415	COG4991	sh3 domain protein
CK238_RS13415	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK238_RS13425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK238_RS13435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CK238_RS13435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CK238_RS13440	COG5416	Lipopolysaccharide assembly protein A domain
CK238_RS13445	COG0490	domain, Protein
CK238_RS13450	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK238_RS13450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK238_RS13460	COG2244	polysaccharide biosynthetic process
CK238_RS13465	COG2323	membrane
CK238_RS13475	COG1862	Preprotein translocase
CK238_RS13520	COG1388	LysM domain
CK238_RS13530	COG0157	Belongs to the NadC ModD family
CK238_RS13535	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CK238_RS13540	COG1104	cysteine desulfurase activity
CK238_RS13545	COG1827	regulation of RNA biosynthetic process
CK238_RS13550	COG0077	Prephenate dehydratase
CK238_RS13565	COG3290	protein histidine kinase activity
CK238_RS13570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CK238_RS13575	COG2868	ribosomal protein
CK238_RS13585	COG1994	Peptidase M50
CK238_RS13590	COG0739	heme binding
CK238_RS13595	COG2894	cell division
CK238_RS13605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CK238_RS13615	COG1077	Cell shape determining protein MreB Mrl
CK238_RS13635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CK238_RS13640	COG0285	dihydrofolate synthase activity
CK238_RS13645	COG0525	valine-tRNA ligase activity
CK238_RS13655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK238_RS13660	COG1388	LysM domain
CK238_RS13670	COG0113	porphobilinogen synthase activity
CK238_RS13675	COG1587	Uroporphyrinogen-III synthase
CK238_RS13685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK238_RS13705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CK238_RS13710	COG0470	DNA polymerase III
CK238_RS13710	COG1067	ATP-dependent peptidase activity
CK238_RS13725	COG0457	Tetratricopeptide repeat
CK238_RS13725	COG1477	protein flavinylation
CK238_RS13740	COG0473	3-isopropylmalate dehydrogenase activity
CK238_RS13755	COG0440	acetolactate synthase activity
CK238_RS13760	COG0028	Belongs to the TPP enzyme family
CK238_RS13785	COG0622	Phosphoesterase
CK238_RS13790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CK238_RS13800	COG5401	PFAM Sporulation and spore germination
CK238_RS13815	COG2197	response regulator
CK238_RS13820	COG0824	Thioesterase
CK238_RS13825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CK238_RS13830	COG1053	succinate dehydrogenase
CK238_RS13835	COG2009	succinate dehydrogenase
CK238_RS13840	COG1719	4-vinyl reductase, 4VR
CK238_RS13845	COG0527	aspartate kinase activity
CK238_RS13860	COG3118	belongs to the thioredoxin family
CK238_RS13865	COG3534	alpha-L-arabinofuranosidase
CK238_RS13870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CK238_RS13875	COG2086	electron transfer activity
CK238_RS13880	COG1024	Enoyl-CoA hydratase
CK238_RS13885	COG1309	transcriptional regulator
CK238_RS13890	COG0318	PFAM AMP-dependent synthetase and ligase
CK238_RS13900	COG3766	membrane
CK238_RS13910	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CK238_RS13910	COG1796	DNA polymerase
CK238_RS13915	COG1286	toxin biosynthetic process
CK238_RS13930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK238_RS13930	COG0072	phenylalanine-tRNA ligase activity
CK238_RS13935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CK238_RS13940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK238_RS13950	COG3835	regulator
CK238_RS13955	COG0277	FAD linked oxidase domain protein
CK238_RS13960	COG0247	lactate metabolic process
CK238_RS13965	COG1966	Carbon starvation protein
CK238_RS13970	COG3534	alpha-L-arabinofuranosidase
CK238_RS13975	COG0395	ABC-type sugar transport system, permease component
CK238_RS13980	COG1175	transmembrane transport
CK238_RS13985	COG1653	transport
CK238_RS13995	COG0647	UMP catabolic process
CK238_RS14000	COG0235	Class ii aldolase
CK238_RS14005	COG1069	ribulokinase activity
CK238_RS14010	COG2160	L-arabinose isomerase activity
CK238_RS14015	COG3507	Belongs to the glycosyl hydrolase 43 family
CK238_RS14020	COG1363	Peptidase, m42
CK238_RS14030	COG3326	Membrane
CK238_RS14045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CK238_RS14050	COG1346	cytolysis
CK238_RS14055	COG1380	Effector of murein hydrolase LrgA
CK238_RS14060	COG3279	Response regulator of the LytR AlgR family
CK238_RS14065	COG3275	phosphorelay sensor kinase activity
CK238_RS14075	COG1011	Hydrolase
CK238_RS14090	COG0398	Pfam SNARE associated Golgi protein
CK238_RS14095	COG1484	DNA-dependent DNA replication
CK238_RS14100	COG3611	Membrane attachment protein
CK238_RS14115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK238_RS14120	COG1733	regulation of RNA biosynthetic process
CK238_RS14125	COG2814	Major facilitator Superfamily
CK238_RS14130	COG0656	L-ascorbic acid biosynthetic process
CK238_RS14135	COG0237	dephospho-CoA kinase activity
CK238_RS14140	COG1971	Probably functions as a manganese efflux pump
CK238_RS14145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CK238_RS14150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK238_RS14150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK238_RS14155	COG5002	protein histidine kinase activity
CK238_RS14160	COG0745	RESPONSE REGULATOR receiver
CK238_RS14170	COG0538	isocitrate dehydrogenase activity
CK238_RS14175	COG0372	Belongs to the citrate synthase family
CK238_RS14180	COG0457	Tetratricopeptide repeat
CK238_RS14205	COG0628	permease
CK238_RS14210	COG3030	protein affecting phage T7 exclusion by the F plasmid
CK238_RS14215	COG0469	pyruvate kinase activity
CK238_RS14235	COG0281	malic enzyme
CK238_RS14240	COG0587	DNA-directed DNA polymerase activity
CK238_RS14260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CK238_RS14270	COG4109	DRTGG domain
CK238_RS14280	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS14295	COG0521	Mo-molybdopterin cofactor biosynthetic process
CK238_RS14305	COG0827	DNA restriction-modification system
CK238_RS14310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CK238_RS14315	COG3874	Sporulation protein YtfJ
CK238_RS14325	COG1714	RDD family
CK238_RS14330	COG0616	signal peptide processing
CK238_RS14335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK238_RS14340	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CK238_RS14345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK238_RS14360	COG1104	cysteine desulfurase activity
CK238_RS14365	COG1114	Component of the transport system for branched-chain amino acids
CK238_RS14375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CK238_RS14380	COG1309	transcriptional regulator
CK238_RS14385	COG1956	GAF domain-containing protein
CK238_RS14390	COG2203	Gaf domain
CK238_RS14390	COG2199	diguanylate cyclase activity
CK238_RS14405	COG4282	regulation of fungal-type cell wall biogenesis
CK238_RS14460	COG1017	nitric oxide dioxygenase activity
CK238_RS14460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK238_RS14470	COG0693	protein deglycase activity
CK238_RS14485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CK238_RS14490	COG1378	Sugar-specific transcriptional regulator TrmB
CK238_RS14515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK238_RS14520	COG0454	-acetyltransferase
CK238_RS14525	COG0517	IMP dehydrogenase activity
CK238_RS14530	COG0123	including yeast histone deacetylase and acetoin utilization protein
CK238_RS14535	COG1360	Flagellar Motor Protein
CK238_RS14540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CK238_RS14545	COG1609	Transcriptional regulator
CK238_RS14550	COG1605	Chorismate mutase
CK238_RS14550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CK238_RS14555	COG3118	belongs to the thioredoxin family
CK238_RS14560	COG4980	gas vesicle protein
CK238_RS14565	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CK238_RS14575	COG1674	ftsk spoiiie
CK238_RS14580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK238_RS14590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK238_RS14610	COG1363	Peptidase, m42
CK238_RS14615	COG5584	Small secreted protein
CK238_RS14620	COG0281	malic enzyme
CK238_RS14625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK238_RS14640	COG0510	thiamine kinase activity
CK238_RS14645	COG1597	lipid kinase activity
CK238_RS14655	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CK238_RS14660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK238_RS14665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK238_RS14670	COG2252	PERMEase
CK238_RS14675	COG4473	ABC transporter
CK238_RS14680	COG1131	(ABC) transporter
CK238_RS14685	COG1349	DNA-binding transcription factor activity
CK238_RS14690	COG1187	pseudouridine synthase activity
CK238_RS14695	COG2244	polysaccharide biosynthetic process
CK238_RS14700	COG2081	HI0933 family
CK238_RS14705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK238_RS14715	COG1609	Transcriptional regulator
CK238_RS14720	COG1653	transport
CK238_RS14725	COG1175	transmembrane transport
CK238_RS14730	COG0395	ABC-type sugar transport system, permease component
CK238_RS14735	COG1486	melibiose metabolic process
CK238_RS14745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK238_RS14760	COG1366	Belongs to the anti-sigma-factor antagonist family
CK238_RS14760	COG2202	Pas domain
CK238_RS14765	COG2814	Major facilitator Superfamily
CK238_RS14770	COG5522	Integral membrane protein (intg_mem_TP0381)
CK238_RS14775	COG0577	efflux transmembrane transporter activity
CK238_RS14780	COG1136	(ABC) transporter
CK238_RS14785	COG2205	protein histidine kinase activity
CK238_RS14790	COG0745	RESPONSE REGULATOR receiver
CK238_RS14795	COG0577	efflux transmembrane transporter activity
CK238_RS14800	COG1136	(ABC) transporter
CK238_RS14820	COG1131	(ABC) transporter
CK238_RS14825	COG1725	Transcriptional regulator
CK238_RS14835	COG0640	Transcriptional regulator
CK238_RS14840	COG0477	Major facilitator Superfamily
CK238_RS14845	COG1242	4 iron, 4 sulfur cluster binding
CK238_RS14850	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CK238_RS14860	COG0584	glycerophosphoryl diester phosphodiesterase
CK238_RS14870	COG2267	carboxylic ester hydrolase activity
CK238_RS14875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CK238_RS14880	COG1113	amino acid transport
CK238_RS14885	COG0367	asparagine synthase
CK238_RS14905	COG1506	peptidase
CK238_RS14910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK238_RS14915	COG1116	anion transmembrane transporter activity
CK238_RS14920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK238_RS14925	COG0494	nUDIX hydrolase
CK238_RS14930	COG4824	toxin secretion phage lysis holin
CK238_RS14935	COG0783	Belongs to the Dps family
CK238_RS14960	COG0288	reversible hydration of carbon dioxide
CK238_RS14970	COG1271	oxidase subunit
CK238_RS14975	COG1294	oxidase, subunit
CK238_RS14985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CK238_RS14990	COG1321	iron dependent repressor
CK238_RS14990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CK238_RS14995	COG1121	(ABC) transporter
CK238_RS15000	COG0803	Belongs to the bacterial solute-binding protein 9 family
CK238_RS15005	COG4948	Mandelate Racemase Muconate Lactonizing
CK238_RS15015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CK238_RS15020	COG0596	Alpha beta hydrolase
CK238_RS15030	COG1169	isochorismate synthase
CK238_RS15035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK238_RS15040	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CK238_RS15165	COG3859	Proton-coupled thiamine transporter YuaJ
CK238_RS15170	COG2268	Band 7 protein
CK238_RS15175	COG1585	Membrane protein implicated in regulation of membrane protease activity
CK238_RS15180	COG2318	DinB family
CK238_RS15190	COG1454	alcohol dehydrogenase
CK238_RS15195	COG1012	belongs to the aldehyde dehydrogenase family
CK238_RS15200	COG1510	regulation of RNA biosynthetic process
CK238_RS15210	COG0569	domain protein
CK238_RS15215	COG1705	Flagellar rod assembly protein muramidase FlgJ
CK238_RS15220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK238_RS15220	COG1017	nitric oxide dioxygenase activity
CK238_RS15240	COG0457	Tetratricopeptide repeat
CK238_RS15275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CK238_RS15290	COG0628	permease
CK238_RS15295	COG0673	inositol 2-dehydrogenase activity
CK238_RS15300	COG0693	protein deglycase activity
CK238_RS15305	COG0840	transmembrane signaling receptor activity
CK238_RS15310	COG0840	transmembrane signaling receptor activity
CK238_RS15315	COG0840	transmembrane signaling receptor activity
CK238_RS15320	COG0840	transmembrane signaling receptor activity
CK238_RS15335	COG2070	2-Nitropropane dioxygenase
CK238_RS15340	COG0432	Pfam Uncharacterised protein family UPF0047
CK238_RS15345	COG0366	Alpha amylase catalytic
CK238_RS15350	COG1253	flavin adenine dinucleotide binding
CK238_RS15355	COG2738	Putative neutral zinc metallopeptidase
CK238_RS15370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK238_RS15400	COG1335	isochorismatase
CK238_RS15415	COG2155	Conserved Protein
CK238_RS15425	COG1098	S1 RNA binding domain
CK238_RS15430	COG0436	Aminotransferase
CK238_RS15435	COG1522	sequence-specific DNA binding
CK238_RS15440	COG2267	carboxylic ester hydrolase activity
CK238_RS15450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CK238_RS15455	COG2205	protein histidine kinase activity
CK238_RS15465	COG5018	Exonuclease
CK238_RS15470	COG2814	Major facilitator Superfamily
CK238_RS15475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK238_RS15480	COG3011	Protein conserved in bacteria
CK238_RS15490	COG3290	protein histidine kinase activity
CK238_RS15495	COG4565	transcriptional regulatory protein
CK238_RS15500	COG1744	ABC transporter substrate-binding protein PnrA-like
CK238_RS15505	COG3845	ABC transporter
CK238_RS15510	COG4603	Belongs to the binding-protein-dependent transport system permease family
CK238_RS15515	COG1079	Belongs to the binding-protein-dependent transport system permease family
CK238_RS15525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CK238_RS15525	COG2111	Na H antiporter
CK238_RS15530	COG2111	Na H antiporter
CK238_RS15535	COG1006	Multisubunit Na H antiporter MnhC subunit
CK238_RS15540	COG0651	ATP synthesis coupled electron transport
CK238_RS15545	COG1863	multisubunit Na H antiporter MnhE subunit
CK238_RS15550	COG2212	antiporter activity
CK238_RS15555	COG1320	monovalent cation:proton antiporter activity
CK238_RS15560	COG2050	protein possibly involved in aromatic compounds catabolism
CK238_RS15565	COG2197	response regulator
CK238_RS15570	COG4585	Histidine kinase
CK238_RS15580	COG0142	geranyltranstransferase activity
CK238_RS15600	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CK238_RS15605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CK238_RS15610	COG1335	isochorismatase
CK238_RS15615	COG5506	Protein of unknown function (DUF1694)
CK238_RS15630	COG0628	permease
CK238_RS15640	COG1418	mRNA catabolic process
CK238_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS15655	COG1511	domain protein
CK238_RS15660	COG0433	COG0433 Predicted ATPase
CK238_RS15660	COG1674	ftsk spoiiie
CK238_RS15665	COG4499	WXG100 protein secretion system (Wss), protein YukC
CK238_RS15670	COG5417	Belongs to the EsaB family
CK238_RS15675	COG4842	Belongs to the WXG100 family
CK238_RS15680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CK238_RS15680	COG2508	Transcriptional regulator
CK238_RS15685	COG0686	Belongs to the AlaDH PNT family
CK238_RS15690	COG5634	Uncharacterized conserved protein (DUF2278)
CK238_RS15695	COG3251	PFAM MbtH domain protein
CK238_RS15700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK238_RS15705	COG3433	isochorismatase activity
CK238_RS15705	COG1535	isochorismatase
CK238_RS15710	COG1021	2,3-dihydroxybenzoate-AMP ligase
CK238_RS15715	COG1169	isochorismate synthase
CK238_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS15725	COG2819	hydrolase of the alpha beta superfamily
CK238_RS15730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CK238_RS15735	COG1268	BioY protein
CK238_RS15740	COG2056	Na+-H+ antiporter family
CK238_RS15750	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CK238_RS15755	COG3584	3D domain protein
CK238_RS15770	COG1252	NADH dehydrogenase
CK238_RS15800	COG1131	(ABC) transporter
CK238_RS15820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK238_RS15825	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CK238_RS15830	COG0316	Belongs to the HesB IscA family
CK238_RS15840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK238_RS15850	COG1252	NADH dehydrogenase
CK238_RS15855	COG4837	Protein of unknown function (DUF1462)
CK238_RS15860	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CK238_RS15865	COG1506	peptidase
CK238_RS15865	COG0823	Involved in the tonB-independent uptake of proteins
CK238_RS15865	COG4946	Tricorn protease homolog
CK238_RS15875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CK238_RS15880	COG0460	homoserine dehydrogenase
CK238_RS15885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK238_RS15890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CK238_RS15895	COG0647	UMP catabolic process
CK238_RS15900	COG2445	Protein of unknown function DUF86
CK238_RS15905	COG4470	Protein conserved in bacteria
CK238_RS15920	COG0739	heme binding
CK238_RS15930	COG0737	Belongs to the 5'-nucleotidase family
CK238_RS15935	COG0730	response to heat
CK238_RS15940	COG1801	Protein of unknown function DUF72
CK238_RS15955	COG2508	Transcriptional regulator
CK238_RS15960	COG0457	Tetratricopeptide repeat
CK238_RS15975	COG2814	Major facilitator Superfamily
CK238_RS15980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CK238_RS15985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK238_RS15990	COG2356	endonuclease I
CK238_RS15995	COG3842	ATPase activity
CK238_RS16000	COG2188	Transcriptional regulator
CK238_RS16005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK238_RS16010	COG0395	ABC-type sugar transport system, permease component
CK238_RS16015	COG1175	transmembrane transport
CK238_RS16020	COG1653	transport
CK238_RS16025	COG2222	sugar isomerase
CK238_RS16030	COG0789	Transcriptional regulator
CK238_RS16055	COG0322	excinuclease ABC activity
CK238_RS16060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK238_RS16065	COG2226	methyltransferase
CK238_RS16080	COG3409	Peptidoglycan-binding domain 1 protein
CK238_RS16085	COG0719	Fe-S assembly protein
CK238_RS16090	COG0822	iron-sulfur transferase activity
CK238_RS16095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CK238_RS16100	COG0719	Fe-S assembly protein
CK238_RS16105	COG0396	ATPase activity
CK238_RS16115	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CK238_RS16120	COG1464	Belongs to the NlpA lipoprotein family
CK238_RS16125	COG2011	ABC-type metal ion transport system permease component
CK238_RS16130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CK238_RS16140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK238_RS16145	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CK238_RS16160	COG1393	Belongs to the ArsC family
CK238_RS16165	COG1960	acyl-CoA dehydrogenase activity
CK238_RS16170	COG0183	Belongs to the thiolase family
CK238_RS16175	COG1024	Enoyl-CoA hydratase
CK238_RS16175	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK238_RS16195	COG5577	PFAM Coat F domain
CK238_RS16200	COG1846	Transcriptional regulator
CK238_RS16205	COG0477	Major facilitator Superfamily
CK238_RS16235	COG1120	ATPase activity
CK238_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS16255	COG0783	Belongs to the Dps family
CK238_RS16260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK238_RS16265	COG0745	RESPONSE REGULATOR receiver
CK238_RS16270	COG2770	Histidine kinase
CK238_RS16270	COG2205	protein histidine kinase activity
CK238_RS16280	COG1309	transcriptional regulator
CK238_RS16285	COG0114	fumarate hydratase activity
CK238_RS16295	COG0697	spore germination
CK238_RS16300	COG0814	amino acid
CK238_RS16310	COG2197	response regulator
CK238_RS16315	COG4585	Histidine kinase
CK238_RS16320	COG4758	membrane
CK238_RS16325	COG3595	metallopeptidase activity
CK238_RS16330	COG1842	Phage shock protein A
CK238_RS16335	COG4758	membrane
CK238_RS16340	COG2814	Major facilitator Superfamily
CK238_RS16345	COG2096	Adenosyltransferase
CK238_RS16350	COG1120	ATPase activity
CK238_RS16355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK238_RS16360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK238_RS16365	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS16370	COG3386	PFAM SMP-30 Gluconolaconase
CK238_RS16375	COG2205	protein histidine kinase activity
CK238_RS16380	COG0745	RESPONSE REGULATOR receiver
CK238_RS16390	COG1191	sigma factor activity
CK238_RS16400	COG2140	Oxalate decarboxylase
CK238_RS16410	COG1120	ATPase activity
CK238_RS16415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK238_RS16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK238_RS16425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK238_RS16430	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CK238_RS16435	COG0531	amino acid
CK238_RS16450	COG1988	membrane-bound metal-dependent
CK238_RS16460	COG1910	domain protein
CK238_RS16465	COG0725	ABC transporter, periplasmic molybdate-binding protein
CK238_RS16470	COG4149	molybdate abc transporter
CK238_RS16475	COG2197	response regulator
CK238_RS16480	COG3850	Histidine kinase
CK238_RS16485	COG1131	(ABC) transporter
CK238_RS16495	COG0842	Transport permease protein
CK238_RS16500	COG0656	L-ascorbic acid biosynthetic process
CK238_RS16525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK238_RS16530	COG3973	AAA domain
CK238_RS16535	COG2860	membrane
CK238_RS16545	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CK238_RS16550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK238_RS16555	COG2217	Heavy metal translocating P-type atpase
CK238_RS16560	COG2217	Heavy metal translocating P-type atpase
CK238_RS16565	COG2608	mercury ion transmembrane transporter activity
CK238_RS16570	COG1937	Protein conserved in bacteria
CK238_RS16575	COG0673	inositol 2-dehydrogenase activity
CK238_RS16590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK238_RS16595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CK238_RS16600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK238_RS16605	COG1126	abc transporter atp-binding protein
CK238_RS16610	COG0765	amino acid transport
CK238_RS16615	COG0765	amino acid transport
CK238_RS16620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK238_RS16625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK238_RS16630	COG0454	-acetyltransferase
CK238_RS16635	COG0583	DNA-binding transcription factor activity
CK238_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS16645	COG2732	(Barnase) inhibitor
CK238_RS16655	COG2732	(Barnase) inhibitor
CK238_RS16675	COG4824	toxin secretion phage lysis holin
CK238_RS16695	COG5434	Belongs to the glycosyl hydrolase 28 family
CK238_RS16700	COG1705	Flagellar rod assembly protein muramidase FlgJ
CK238_RS16700	COG1388	LysM domain
CK238_RS16775	COG4626	Terminase
CK238_RS16775	COG1802	Transcriptional regulator
CK238_RS16805	COG0582	viral genome integration into host DNA
CK238_RS16810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CK238_RS16935	COG0582	viral genome integration into host DNA
CK238_RS16950	COG0557	exoribonuclease II activity
CK238_RS16955	COG1647	Serine aminopeptidase, S33
CK238_RS16960	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK238_RS16965	COG1476	TRANSCRIPTIONal
CK238_RS16970	COG1396	sequence-specific DNA binding
CK238_RS16975	COG1396	sequence-specific DNA binding
CK238_RS16980	COG1733	regulation of RNA biosynthetic process
CK238_RS17005	COG1131	(ABC) transporter
CK238_RS17010	COG1174	glycine betaine transport
CK238_RS17015	COG1732	Glycine betaine
CK238_RS17020	COG1174	glycine betaine transport
CK238_RS17025	COG1125	glycine betaine transport
CK238_RS17025	COG0517	IMP dehydrogenase activity
CK238_RS17030	COG1510	regulation of RNA biosynthetic process
CK238_RS17035	COG1174	glycine betaine transport
CK238_RS17040	COG1732	Glycine betaine
CK238_RS17045	COG1174	glycine betaine transport
CK238_RS17050	COG1125	glycine betaine transport
CK238_RS17050	COG0517	IMP dehydrogenase activity
CK238_RS17055	COG1510	regulation of RNA biosynthetic process
CK238_RS17060	COG2095	MarC family integral membrane protein
CK238_RS17070	COG3064	Membrane
CK238_RS17075	COG4640	response to antibiotic
CK238_RS17080	COG0456	acetyltransferase
CK238_RS17100	COG0126	phosphoglycerate kinase activity
CK238_RS17110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK238_RS17115	COG2390	Transcriptional regulator
CK238_RS17120	COG2814	Major facilitator Superfamily
CK238_RS17125	COG1609	Transcriptional regulator
CK238_RS17135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK238_RS17140	COG0583	DNA-binding transcription factor activity
CK238_RS17145	COG0697	spore germination
CK238_RS17150	COG1113	amino acid transport
CK238_RS17155	COG1737	Transcriptional regulator
CK238_RS17160	COG1070	Carbohydrate kinase
CK238_RS17185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK238_RS17190	COG2186	Transcriptional regulator
CK238_RS17195	COG1620	l-lactate permease
CK238_RS17200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CK238_RS17210	COG5039	Polysaccharide pyruvyl transferase
CK238_RS17215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK238_RS17220	COG0110	maltose O-acetyltransferase activity
CK238_RS17225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CK238_RS17230	COG2244	polysaccharide biosynthetic process
CK238_RS17235	COG1216	Glycosyl transferase, family 2
CK238_RS17240	COG5039	Polysaccharide pyruvyl transferase
CK238_RS17245	COG1216	Glycosyl transferase, family 2
CK238_RS17255	COG0438	transferase activity, transferring glycosyl groups
CK238_RS17260	COG1215	transferase activity, transferring glycosyl groups
CK238_RS17265	COG0438	transferase activity, transferring glycosyl groups
CK238_RS17270	COG1086	Polysaccharide biosynthesis protein
CK238_RS17275	COG0489	protein tyrosine kinase activity
CK238_RS17280	COG3944	biosynthesis protein
CK238_RS17285	COG1396	sequence-specific DNA binding
CK238_RS17290	COG2272	Belongs to the type-B carboxylesterase lipase family
CK238_RS17300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CK238_RS17305	COG2364	Membrane
CK238_RS17310	COG0456	acetyltransferase
CK238_RS17315	COG3479	Phenolic acid decarboxylase
CK238_RS17370	COG2223	nitrite transmembrane transporter activity
CK238_RS17375	COG1609	Transcriptional regulator
CK238_RS17385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK238_RS17390	COG0366	Alpha amylase catalytic
CK238_RS17395	COG1554	hydrolase, family 65, central catalytic
CK238_RS17400	COG5521	maltodextrose utilization protein MalA
CK238_RS17405	COG3833	ABC-type maltose transport systems, permease component
CK238_RS17410	COG1175	transmembrane transport
CK238_RS17415	COG2182	Extracellular solute-binding protein
CK238_RS17420	COG0366	Alpha amylase catalytic
CK238_RS17425	COG1609	Transcriptional regulator
CK238_RS17430	COG1611	Belongs to the LOG family
CK238_RS17435	COG1694	Mazg nucleotide pyrophosphohydrolase
CK238_RS17440	COG0659	secondary active sulfate transmembrane transporter activity
CK238_RS17445	COG0288	reversible hydration of carbon dioxide
CK238_RS17455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK238_RS17460	COG4290	ribonuclease
CK238_RS17465	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CK238_RS17470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK238_RS17480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CK238_RS17490	COG1051	belongs to the nudix hydrolase family
CK238_RS17495	COG0492	ferredoxin-NADP+ reductase activity
CK238_RS17500	COG0791	NLP P60 protein
CK238_RS17500	COG3883	PFAM NLP P60 protein
CK238_RS17505	COG0457	Tetratricopeptide repeat
CK238_RS17510	COG5002	protein histidine kinase activity
CK238_RS17515	COG0745	RESPONSE REGULATOR receiver
CK238_RS17520	COG1132	(ABC) transporter
CK238_RS17525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CK238_RS17525	COG0140	phosphoribosyl-ATP diphosphatase activity
CK238_RS17550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CK238_RS17565	COG4990	cell redox homeostasis
CK238_RS17570	COG0110	maltose O-acetyltransferase activity
CK238_RS17590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CK238_RS17600	COG2188	Transcriptional regulator
CK238_RS17605	COG1309	transcriptional regulator
CK238_RS17610	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CK238_RS17615	COG1950	PFAM Membrane protein of
CK238_RS17620	COG1983	PspC domain protein
CK238_RS17625	COG3595	metallopeptidase activity
CK238_RS17640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CK238_RS17650	COG4897	Protein conserved in bacteria
CK238_RS17655	COG0574	Belongs to the PEP-utilizing enzyme family
CK238_RS17655	COG3848	Pyruvate phosphate dikinase
CK238_RS17660	COG1309	transcriptional regulator
CK238_RS17665	COG2814	Major facilitator Superfamily
CK238_RS17675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK238_RS17685	COG0793	Belongs to the peptidase S41A family
CK238_RS17685	COG3409	Peptidoglycan-binding domain 1 protein
CK238_RS17690	COG3420	alginic acid biosynthetic process
CK238_RS17695	COG2177	Part of the ABC transporter FtsEX involved in
CK238_RS17700	COG2884	Cell division ATP-binding protein ftsE
CK238_RS17705	COG2010	Cytochrome c
CK238_RS17710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK238_RS17725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CK238_RS17740	COG1516	flagellar protein fliS
CK238_RS17745	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CK238_RS17750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CK238_RS17770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CK238_RS17775	COG4786	Flagellar basal body rod
CK238_RS17775	COG1256	bacterial-type flagellum assembly
CK238_RS17780	COG3418	PFAM FlgN family protein
CK238_RS17785	COG2747	anti-sigma28 factor FlgM
CK238_RS17795	COG1040	competence protein
CK238_RS17805	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CK238_RS17810	COG1307	EDD domain protein, DegV family
CK238_RS17815	COG2197	response regulator
CK238_RS17820	COG4585	Histidine kinase
CK238_RS17825	COG1739	Uncharacterized protein family UPF0029
CK238_RS17830	COG1316	TRANSCRIPTIONal
CK238_RS17835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CK238_RS17840	COG0438	transferase activity, transferring glycosyl groups
CK238_RS17845	COG1215	transferase activity, transferring glycosyl groups
CK238_RS17850	COG3206	protein involved in exopolysaccharide biosynthesis
CK238_RS17855	COG3307	-O-antigen
CK238_RS17860	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CK238_RS17865	COG0438	transferase activity, transferring glycosyl groups
CK238_RS17865	COG0297	glycogen (starch) synthase activity
CK238_RS17870	COG2244	polysaccharide biosynthetic process
CK238_RS17880	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK238_RS17880	COG2247	cell wall binding repeat
CK238_RS17885	COG2385	sporulation resulting in formation of a cellular spore
CK238_RS17885	COG2247	cell wall binding repeat
CK238_RS17895	COG1316	TRANSCRIPTIONal
CK238_RS17900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CK238_RS17905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CK238_RS17910	COG1134	teichoic acid transport
CK238_RS17915	COG1682	transport, permease protein
CK238_RS17920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CK238_RS17925	COG0438	transferase activity, transferring glycosyl groups
CK238_RS17930	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CK238_RS17935	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CK238_RS17940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CK238_RS17945	COG4193	domain, Protein
CK238_RS17950	COG1482	cell wall glycoprotein biosynthetic process
CK238_RS17955	COG0697	spore germination
CK238_RS17960	COG0814	amino acid
CK238_RS17970	COG1215	transferase activity, transferring glycosyl groups
CK238_RS17975	COG2814	Major facilitator Superfamily
CK238_RS17980	COG1316	TRANSCRIPTIONal
CK238_RS17985	COG0561	phosphatase activity
CK238_RS17990	COG2433	Pfam Transposase IS66
CK238_RS17995	COG0791	NLP P60 protein
CK238_RS18005	COG2843	Capsule synthesis protein
CK238_RS18015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CK238_RS18025	COG0697	spore germination
CK238_RS18030	COG0814	amino acid
CK238_RS18040	COG1609	Transcriptional regulator
CK238_RS18045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK238_RS18055	COG1129	ABC transporter
CK238_RS18060	COG1172	Belongs to the binding-protein-dependent transport system permease family
CK238_RS18065	COG1879	ABC-type sugar transport system periplasmic component
CK238_RS18070	COG3103	Sh3 type 3 domain protein
CK238_RS18075	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK238_RS18080	COG3527	Alpha-acetolactate decarboxylase
CK238_RS18085	COG0028	Belongs to the TPP enzyme family
CK238_RS18090	COG0583	DNA-binding transcription factor activity
CK238_RS18095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CK238_RS18110	COG5337	Spore coat protein CotH
CK238_RS18120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK238_RS18130	COG0405	Gamma-glutamyltransferase
CK238_RS18135	COG1522	sequence-specific DNA binding
CK238_RS18140	COG2059	Chromate
CK238_RS18145	COG2059	Chromate
CK238_RS18155	COG0655	NAD(P)H dehydrogenase (quinone) activity
CK238_RS18160	COG0583	DNA-binding transcription factor activity
CK238_RS18205	COG3878	Protein conserved in bacteria
CK238_RS18210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CK238_RS18215	COG4464	protein tyrosine phosphatase activity
CK238_RS18220	COG0489	protein tyrosine kinase activity
CK238_RS18225	COG3944	biosynthesis protein
CK238_RS18240	COG4715	Zinc finger, swim domain protein
CK238_RS18245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CK238_RS18250	COG0561	phosphatase activity
CK238_RS18255	COG1349	DNA-binding transcription factor activity
CK238_RS18260	COG0629	single-stranded DNA binding
CK238_RS18285	COG0457	Tetratricopeptide repeat
CK238_RS18290	COG4786	Flagellar basal body rod
CK238_RS18295	COG4786	Flagellar basal body rod
CK238_RS18300	COG1077	Cell shape determining protein MreB Mrl
CK238_RS18305	COG1609	Transcriptional regulator
CK238_RS18310	COG1846	Transcriptional regulator
CK238_RS18315	COG2814	Major facilitator Superfamily
CK238_RS18320	COG1953	Uracil, thiamine, allantoin
CK238_RS18325	COG0477	Major facilitator Superfamily
CK238_RS18330	COG1335	isochorismatase
CK238_RS18335	COG0004	ammonium transporteR
CK238_RS18340	COG0347	Belongs to the P(II) protein family
CK238_RS18345	COG0772	Belongs to the SEDS family
CK238_RS18350	COG0671	phosphoesterase, PA-phosphatase related
CK238_RS18360	COG0739	heme binding
CK238_RS18365	COG1247	-acetyltransferase
CK238_RS18380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK238_RS18390	COG0726	polysaccharide deacetylase
CK238_RS18400	COG1959	2 iron, 2 sulfur cluster binding
CK238_RS18415	COG0831	urea catabolic process
CK238_RS18425	COG1994	Peptidase M50
CK238_RS18430	COG0457	Tetratricopeptide repeat
CK238_RS18440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CK238_RS18445	COG2304	oxidoreductase activity
CK238_RS18450	COG2304	oxidoreductase activity
CK238_RS18455	COG2385	sporulation resulting in formation of a cellular spore
CK238_RS18460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CK238_RS18470	COG4836	Membrane
CK238_RS18540	COG0698	ribose 5-phosphate isomerase
CK238_RS18545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CK238_RS18555	COG0009	L-threonylcarbamoyladenylate synthase
CK238_RS18560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CK238_RS18580	COG2890	protein-(glutamine-N5) methyltransferase activity
CK238_RS18585	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CK238_RS18590	COG0346	lactoylglutathione lyase activity
CK238_RS18595	COG0789	Transcriptional regulator
CK238_RS18600	COG0679	Auxin Efflux Carrier
CK238_RS18605	COG0281	malic enzyme
CK238_RS18620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CK238_RS18625	COG1494	fructose-1,6-bisphosphatase
CK238_RS18630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CK238_RS18645	COG0191	fructose-bisphosphate aldolase activity
CK238_RS18650	COG2204	response regulator
CK238_RS18655	COG4821	SIS domain
CK238_RS18670	COG0247	lactate metabolic process
CK238_RS18670	COG2181	nitrate reductase activity
CK238_RS18675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK238_RS18690	COG1132	(ABC) transporter
CK238_RS18695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK238_RS18705	COG2181	nitrate reductase activity
CK238_RS18710	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CK238_RS18715	COG1140	nitrate reductase beta subunit
CK238_RS18720	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CK238_RS18725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK238_RS18735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK238_RS18740	COG2223	nitrite transmembrane transporter activity
CK238_RS18750	COG4506	Protein conserved in bacteria
CK238_RS18755	COG0457	Tetratricopeptide repeat
CK238_RS18765	COG0010	Belongs to the arginase family
CK238_RS18770	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CK238_RS18775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK238_RS18790	COG1994	Peptidase M50
CK238_RS18795	COG1942	4-Oxalocrotonate Tautomerase
CK238_RS18800	COG1846	Transcriptional regulator
CK238_RS18810	COG0531	amino acid
CK238_RS18815	COG3465	dGTPase activity
CK238_RS18820	COG1078	dGTPase activity
CK238_RS18835	COG1695	Transcriptional regulator
CK238_RS18845	COG1131	(ABC) transporter
CK238_RS18850	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CK238_RS18880	COG0583	DNA-binding transcription factor activity
CK238_RS18885	COG2855	membrane
CK238_RS18890	COG0280	phosphate acetyltransferase
CK238_RS18900	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS18905	COG0436	Aminotransferase
CK238_RS18935	COG2814	Major facilitator Superfamily
CK238_RS18940	COG2814	Major facilitator Superfamily
CK238_RS18945	COG0833	amino acid
CK238_RS18950	COG4187	Peptidase family M20/M25/M40
CK238_RS18955	COG1012	belongs to the aldehyde dehydrogenase family
CK238_RS18960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CK238_RS18970	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CK238_RS18975	COG1091	dTDP-4-dehydrorhamnose reductase activity
CK238_RS18980	COG1088	dTDP-glucose 4,6-dehydratase activity
CK238_RS18985	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CK238_RS18990	COG3980	spore coat polysaccharide biosynthesis protein
CK238_RS18995	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CK238_RS19000	COG2089	acid synthase
CK238_RS19005	COG0456	acetyltransferase
CK238_RS19010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK238_RS19015	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CK238_RS19020	COG0463	Glycosyl transferase, family 2
CK238_RS19030	COG2363	Small membrane protein
CK238_RS19035	COG2233	PERMEase
CK238_RS19050	COG1216	Glycosyl transferase, family 2
CK238_RS19065	COG1695	Transcriptional regulator
CK238_RS19070	COG0351	phosphomethylpyrimidine kinase
CK238_RS19080	COG1621	beta-fructofuranosidase activity
CK238_RS19085	COG1263	PTS System
CK238_RS19085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK238_RS19090	COG3711	transcriptional antiterminator
CK238_RS19100	COG1404	Belongs to the peptidase S8 family
CK238_RS19105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK238_RS19110	COG0778	Nitroreductase
CK238_RS19115	COG0772	Belongs to the SEDS family
CK238_RS19120	COG0454	-acetyltransferase
CK238_RS19140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CK238_RS19145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CK238_RS19150	COG2261	transglycosylase associated protein
CK238_RS19155	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CK238_RS19160	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CK238_RS19165	COG2246	polysaccharide biosynthetic process
CK238_RS19170	COG1309	transcriptional regulator
CK238_RS19190	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CK238_RS19195	COG2837	iron assimilation
CK238_RS19200	COG2822	iron ion transport
CK238_RS19215	COG0583	DNA-binding transcription factor activity
CK238_RS19225	COG1346	cytolysis
CK238_RS19230	COG1131	(ABC) transporter
CK238_RS19260	COG4895	conserved protein (DUF2196)
CK238_RS19270	COG5504	Zn-dependent protease
CK238_RS19275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CK238_RS19280	COG0346	lactoylglutathione lyase activity
CK238_RS19285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK238_RS19295	COG1442	glycosyl transferase family 8
CK238_RS19300	COG2357	RelA SpoT domain protein
CK238_RS19305	COG1575	Belongs to the MenA family. Type 1 subfamily
CK238_RS19325	COG1696	Membrane protein involved in D-alanine export
CK238_RS19335	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CK238_RS19340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK238_RS19345	COG1486	melibiose metabolic process
CK238_RS19350	COG1447	Phosphotransferase system cellobiose-specific component IIA
CK238_RS19355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK238_RS19360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK238_RS19365	COG3711	transcriptional antiterminator
CK238_RS19365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK238_RS19380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK238_RS19385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK238_RS19395	COG0640	Transcriptional regulator
CK238_RS19400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CK238_RS19405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK238_RS19410	COG1447	Phosphotransferase system cellobiose-specific component IIA
CK238_RS19415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK238_RS19420	COG2723	6-phospho-beta-galactosidase activity
CK238_RS19425	COG1940	carbohydrate kinase activity
CK238_RS19430	COG1482	cell wall glycoprotein biosynthetic process
CK238_RS19440	COG0753	catalase activity
CK238_RS19445	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CK238_RS19450	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CK238_RS19455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CK238_RS19460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CK238_RS19465	COG4988	ABC transporter
CK238_RS19470	COG1294	oxidase, subunit
CK238_RS19475	COG1271	oxidase subunit
CK238_RS19480	COG3493	citrate carrier protein
CK238_RS19485	COG0726	polysaccharide deacetylase
CK238_RS19490	COG3842	ATPase activity
CK238_RS19495	COG2508	Transcriptional regulator
CK238_RS19500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK238_RS19510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK238_RS19520	COG4894	glucomannan catabolic process
CK238_RS19525	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CK238_RS19530	COG0500	methyltransferase
CK238_RS19535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK238_RS19550	COG0753	catalase activity
CK238_RS19550	COG0693	protein deglycase activity
CK238_RS19555	COG2851	Citrate transporter
CK238_RS19560	COG2273	Hydrolase Family 16
CK238_RS19570	COG2270	Major facilitator Superfamily
CK238_RS19575	COG0513	Belongs to the DEAD box helicase family
CK238_RS19650	COG3209	COG3209 Rhs family protein
CK238_RS19660	COG0697	spore germination
CK238_RS19665	COG0589	response to stress
CK238_RS19680	COG0494	nUDIX hydrolase
CK238_RS19685	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CK238_RS19690	COG3507	Belongs to the glycosyl hydrolase 43 family
CK238_RS19715	COG0010	Belongs to the arginase family
CK238_RS19720	COG0833	amino acid
CK238_RS19725	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CK238_RS19730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK238_RS19740	COG2390	Transcriptional regulator
CK238_RS19770	COG1131	(ABC) transporter
CK238_RS19785	COG0561	phosphatase activity
CK238_RS19815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK238_RS19820	COG5294	Protein conserved in bacteria
CK238_RS19825	COG0577	efflux transmembrane transporter activity
CK238_RS19830	COG1136	(ABC) transporter
CK238_RS19835	COG2205	protein histidine kinase activity
CK238_RS19840	COG0745	RESPONSE REGULATOR receiver
CK238_RS19855	COG1082	Xylose isomerase domain protein TIM barrel
CK238_RS19865	COG2814	Major facilitator Superfamily
CK238_RS19895	COG1349	DNA-binding transcription factor activity
CK238_RS19900	COG0667	Aldo Keto reductase
CK238_RS19905	COG2814	Major facilitator Superfamily
CK238_RS19920	COG1028	Short-chain dehydrogenase reductase Sdr
CK238_RS19925	COG2197	response regulator
CK238_RS19930	COG4585	Histidine kinase
CK238_RS19935	COG3239	Fatty acid desaturase
CK238_RS19940	COG1309	transcriptional regulator
CK238_RS19945	COG1012	belongs to the aldehyde dehydrogenase family
CK238_RS19960	COG0640	Transcriptional regulator
CK238_RS19965	COG2814	Major facilitator Superfamily
CK238_RS19980	COG0450	alkyl hydroperoxide reductase
CK238_RS19985	COG3634	alkyl hydroperoxide reductase activity
CK238_RS19990	COG3177	Filamentation induced by cAMP protein fic
CK238_RS19995	COG1113	amino acid transport
CK238_RS20005	COG2080	2 iron, 2 sulfur cluster binding
CK238_RS20020	COG2068	MobA-Related Protein
CK238_RS20075	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CK238_RS20080	COG0667	Aldo Keto reductase
CK238_RS20085	COG0456	acetyltransferase
CK238_RS20090	COG0457	Tetratricopeptide repeat
CK238_RS20095	COG0010	Belongs to the arginase family
CK238_RS20100	COG0833	amino acid
CK238_RS20105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK238_RS20110	COG5658	integral membrane protein
CK238_RS20115	COG0640	Transcriptional regulator
CK238_RS20120	COG3829	transcription factor binding
CK238_RS20130	COG0488	(ABC) transporter
CK238_RS20145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK238_RS20150	COG3850	Histidine kinase
CK238_RS20150	COG5002	protein histidine kinase activity
CK238_RS20155	COG0745	RESPONSE REGULATOR receiver
CK238_RS20165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK238_RS20170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CK238_RS20175	COG4853	Protein conserved in bacteria
CK238_RS20180	COG4863	YycH protein
CK238_RS20185	COG5002	protein histidine kinase activity
CK238_RS20190	COG0745	RESPONSE REGULATOR receiver
CK238_RS20225	COG0346	lactoylglutathione lyase activity
CK238_RS20230	COG0305	Participates in initiation and elongation during chromosome replication
CK238_RS20245	COG3093	addiction module antidote protein HigA
CK238_RS20250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CK238_RS20255	COG0297	glycogen (starch) synthase activity
CK238_RS20265	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CK238_RS20270	COG0438	transferase activity, transferring glycosyl groups
CK238_RS20280	COG2112	serine threonine protein kinase
CK238_RS20290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CK238_RS20295	COG4241	membrane
CK238_RS20305	COG5577	PFAM Coat F domain
CK238_RS20310	COG1733	regulation of RNA biosynthetic process
CK238_RS20320	COG0697	spore germination
CK238_RS20325	COG1621	beta-fructofuranosidase activity
CK238_RS20330	COG1621	beta-fructofuranosidase activity
CK238_RS20335	COG1802	Transcriptional regulator
CK238_RS20340	COG2318	DinB family
CK238_RS20345	COG2211	Major facilitator Superfamily
CK238_RS20350	COG0697	spore germination
CK238_RS20360	COG0778	Nitroreductase
CK238_RS20365	COG1846	Transcriptional regulator
CK238_RS20370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK238_RS20375	COG1846	Transcriptional regulator
CK238_RS20380	COG2153	protein acetylation
CK238_RS20390	COG0546	phosphoglycolate phosphatase activity
CK238_RS20420	COG1404	Belongs to the peptidase S8 family
CK238_RS20430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK238_RS20435	COG0697	spore germination
CK238_RS20470	COG1131	(ABC) transporter
CK238_RS20485	COG1331	Highly conserved protein containing a thioredoxin domain
CK238_RS20490	COG1266	CAAX protease self-immunity
CK238_RS20495	COG0477	Major facilitator Superfamily
CK238_RS20495	COG2814	Major facilitator Superfamily
CK238_RS20500	COG0346	lactoylglutathione lyase activity
CK238_RS20505	COG1609	Transcriptional regulator
CK238_RS20510	COG0708	Exodeoxyribonuclease III
CK238_RS20515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK238_RS20520	COG2169	Transcriptional regulator
CK238_RS20530	COG0629	single-stranded DNA binding
CK238_RS20540	COG0012	GTP binding
CK238_RS20545	COG0243	molybdopterin cofactor binding
CK238_RS20550	COG4481	Protein conserved in bacteria
CK238_RS20555	COG3949	Membrane
CK238_RS20570	COG1475	DNA binding
CK238_RS20575	COG1192	Involved in chromosome partitioning
CK238_RS20600	COG1847	R3H domain protein
CK238_RS20605	COG0706	membrane insertase activity