locus-tag	class	description
CRH11_RS00045	COG3655	Transcriptional regulator
CRH11_RS00075	COG1484	DNA-dependent DNA replication
CRH11_RS00120	COG4974	Belongs to the 'phage' integrase family
CRH11_RS00135	COG0628	permease
CRH11_RS00140	COG0673	inositol 2-dehydrogenase activity
CRH11_RS00145	COG0693	protein deglycase activity
CRH11_RS00150	COG0840	transmembrane signaling receptor activity
CRH11_RS00155	COG0840	transmembrane signaling receptor activity
CRH11_RS00160	COG0840	transmembrane signaling receptor activity
CRH11_RS00165	COG0840	transmembrane signaling receptor activity
CRH11_RS00180	COG2070	2-Nitropropane dioxygenase
CRH11_RS00185	COG0432	Pfam Uncharacterised protein family UPF0047
CRH11_RS00190	COG0366	Alpha amylase catalytic
CRH11_RS00195	COG1253	flavin adenine dinucleotide binding
CRH11_RS00200	COG2738	Putative neutral zinc metallopeptidase
CRH11_RS00215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CRH11_RS00245	COG1335	isochorismatase
CRH11_RS00250	COG1979	alcohol dehydrogenase
CRH11_RS00255	COG1979	alcohol dehydrogenase
CRH11_RS00260	COG2155	Conserved Protein
CRH11_RS00265	COG1098	S1 RNA binding domain
CRH11_RS00270	COG0436	Aminotransferase
CRH11_RS00275	COG1522	sequence-specific DNA binding
CRH11_RS00280	COG2267	carboxylic ester hydrolase activity
CRH11_RS00290	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CRH11_RS00295	COG2205	protein histidine kinase activity
CRH11_RS00305	COG5018	Exonuclease
CRH11_RS00310	COG2814	Major facilitator Superfamily
CRH11_RS00315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRH11_RS00320	COG3011	Protein conserved in bacteria
CRH11_RS00330	COG3290	protein histidine kinase activity
CRH11_RS00335	COG4565	transcriptional regulatory protein
CRH11_RS00340	COG1744	ABC transporter substrate-binding protein PnrA-like
CRH11_RS00345	COG3845	ABC transporter
CRH11_RS00350	COG4603	Belongs to the binding-protein-dependent transport system permease family
CRH11_RS00355	COG1079	Belongs to the binding-protein-dependent transport system permease family
CRH11_RS00365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CRH11_RS00365	COG2111	Na H antiporter
CRH11_RS00370	COG2111	Na H antiporter
CRH11_RS00375	COG1006	Multisubunit Na H antiporter MnhC subunit
CRH11_RS00380	COG0651	ATP synthesis coupled electron transport
CRH11_RS00385	COG1863	multisubunit Na H antiporter MnhE subunit
CRH11_RS00390	COG2212	antiporter activity
CRH11_RS00395	COG1320	monovalent cation:proton antiporter activity
CRH11_RS00400	COG2050	protein possibly involved in aromatic compounds catabolism
CRH11_RS00405	COG2197	response regulator
CRH11_RS00410	COG4585	Histidine kinase
CRH11_RS00420	COG0142	geranyltranstransferase activity
CRH11_RS00440	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CRH11_RS00445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CRH11_RS00450	COG1335	isochorismatase
CRH11_RS00455	COG5506	Protein of unknown function (DUF1694)
CRH11_RS00470	COG0628	permease
CRH11_RS00480	COG1418	mRNA catabolic process
CRH11_RS00485	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS00495	COG1511	domain protein
CRH11_RS00500	COG0433	COG0433 Predicted ATPase
CRH11_RS00500	COG1674	ftsk spoiiie
CRH11_RS00505	COG4499	WXG100 protein secretion system (Wss), protein YukC
CRH11_RS00510	COG5417	Belongs to the EsaB family
CRH11_RS00515	COG4842	Belongs to the WXG100 family
CRH11_RS00520	COG2508	Transcriptional regulator
CRH11_RS00520	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CRH11_RS00525	COG0686	Belongs to the AlaDH PNT family
CRH11_RS00530	COG5634	Uncharacterized conserved protein (DUF2278)
CRH11_RS00535	COG3251	PFAM MbtH domain protein
CRH11_RS00540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS00545	COG3433	isochorismatase activity
CRH11_RS00545	COG1535	isochorismatase
CRH11_RS00550	COG1021	2,3-dihydroxybenzoate-AMP ligase
CRH11_RS00555	COG1169	isochorismate synthase
CRH11_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS00565	COG2819	hydrolase of the alpha beta superfamily
CRH11_RS00570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CRH11_RS00575	COG1268	BioY protein
CRH11_RS00580	COG2056	Na+-H+ antiporter family
CRH11_RS00590	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CRH11_RS00595	COG3584	3D domain protein
CRH11_RS00605	COG1252	NADH dehydrogenase
CRH11_RS00635	COG1131	(ABC) transporter
CRH11_RS00655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRH11_RS00660	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CRH11_RS00665	COG0316	Belongs to the HesB IscA family
CRH11_RS00675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRH11_RS00685	COG1252	NADH dehydrogenase
CRH11_RS00690	COG4837	Protein of unknown function (DUF1462)
CRH11_RS00695	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CRH11_RS00700	COG0823	Involved in the tonB-independent uptake of proteins
CRH11_RS00700	COG4946	Tricorn protease homolog
CRH11_RS00700	COG1506	peptidase
CRH11_RS00710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CRH11_RS00715	COG0460	homoserine dehydrogenase
CRH11_RS00720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CRH11_RS00725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CRH11_RS00730	COG0647	UMP catabolic process
CRH11_RS00735	COG2445	Protein of unknown function DUF86
CRH11_RS00740	COG4470	Protein conserved in bacteria
CRH11_RS00755	COG0739	heme binding
CRH11_RS00765	COG0737	Belongs to the 5'-nucleotidase family
CRH11_RS00770	COG0730	response to heat
CRH11_RS00775	COG1801	Protein of unknown function DUF72
CRH11_RS00790	COG2508	Transcriptional regulator
CRH11_RS00800	COG2814	Major facilitator Superfamily
CRH11_RS00805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CRH11_RS00810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRH11_RS00815	COG2356	endonuclease I
CRH11_RS00820	COG3842	ATPase activity
CRH11_RS00825	COG2188	Transcriptional regulator
CRH11_RS00830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRH11_RS00835	COG0395	ABC-type sugar transport system, permease component
CRH11_RS00840	COG1175	transmembrane transport
CRH11_RS00845	COG1653	transport
CRH11_RS00850	COG2222	sugar isomerase
CRH11_RS00855	COG0789	Transcriptional regulator
CRH11_RS00870	COG0322	excinuclease ABC activity
CRH11_RS00875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRH11_RS00880	COG2226	methyltransferase
CRH11_RS00890	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS00895	COG0719	Fe-S assembly protein
CRH11_RS00900	COG0822	iron-sulfur transferase activity
CRH11_RS00905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CRH11_RS00910	COG0719	Fe-S assembly protein
CRH11_RS00915	COG0396	ATPase activity
CRH11_RS00925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CRH11_RS00930	COG1464	Belongs to the NlpA lipoprotein family
CRH11_RS00935	COG2011	ABC-type metal ion transport system permease component
CRH11_RS00940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CRH11_RS00950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRH11_RS00955	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CRH11_RS00970	COG1393	Belongs to the ArsC family
CRH11_RS00975	COG1960	acyl-CoA dehydrogenase activity
CRH11_RS00980	COG0183	Belongs to the thiolase family
CRH11_RS00985	COG1024	Enoyl-CoA hydratase
CRH11_RS00985	COG1250	3-hydroxyacyl-CoA dehydrogenase
CRH11_RS01005	COG5577	PFAM Coat F domain
CRH11_RS01010	COG1846	Transcriptional regulator
CRH11_RS01015	COG0477	Major facilitator Superfamily
CRH11_RS01020	COG0583	DNA-binding transcription factor activity
CRH11_RS01040	COG1120	ATPase activity
CRH11_RS01055	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS01060	COG0783	Belongs to the Dps family
CRH11_RS01065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRH11_RS01070	COG0745	RESPONSE REGULATOR receiver
CRH11_RS01075	COG2770	Histidine kinase
CRH11_RS01075	COG2205	protein histidine kinase activity
CRH11_RS01085	COG1309	transcriptional regulator
CRH11_RS01090	COG0114	fumarate hydratase activity
CRH11_RS01100	COG0697	spore germination
CRH11_RS01105	COG0814	amino acid
CRH11_RS01115	COG2197	response regulator
CRH11_RS01120	COG4585	Histidine kinase
CRH11_RS01125	COG4758	membrane
CRH11_RS01130	COG3595	metallopeptidase activity
CRH11_RS01135	COG1842	Phage shock protein A
CRH11_RS01140	COG4758	membrane
CRH11_RS01145	COG2814	Major facilitator Superfamily
CRH11_RS01150	COG2096	Adenosyltransferase
CRH11_RS01155	COG1120	ATPase activity
CRH11_RS01160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRH11_RS01165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRH11_RS01170	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS01175	COG3386	PFAM SMP-30 Gluconolaconase
CRH11_RS01180	COG2205	protein histidine kinase activity
CRH11_RS01185	COG0745	RESPONSE REGULATOR receiver
CRH11_RS01195	COG1191	sigma factor activity
CRH11_RS01205	COG2140	Oxalate decarboxylase
CRH11_RS01220	COG1120	ATPase activity
CRH11_RS01225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRH11_RS01230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRH11_RS01235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRH11_RS01240	COG0531	amino acid
CRH11_RS01255	COG1988	membrane-bound metal-dependent
CRH11_RS01260	COG1368	sulfuric ester hydrolase activity
CRH11_RS01265	COG1910	domain protein
CRH11_RS01270	COG0725	ABC transporter, periplasmic molybdate-binding protein
CRH11_RS01275	COG4149	molybdate abc transporter
CRH11_RS01280	COG2197	response regulator
CRH11_RS01285	COG3850	Histidine kinase
CRH11_RS01290	COG1131	(ABC) transporter
CRH11_RS01300	COG0842	Transport permease protein
CRH11_RS01305	COG0656	L-ascorbic acid biosynthetic process
CRH11_RS01330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CRH11_RS01335	COG3973	AAA domain
CRH11_RS01340	COG2860	membrane
CRH11_RS01350	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CRH11_RS01355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CRH11_RS01360	COG2217	Heavy metal translocating P-type atpase
CRH11_RS01365	COG2217	Heavy metal translocating P-type atpase
CRH11_RS01370	COG2608	mercury ion transmembrane transporter activity
CRH11_RS01375	COG1937	Protein conserved in bacteria
CRH11_RS01380	COG0673	inositol 2-dehydrogenase activity
CRH11_RS01395	COG2814	Major facilitator Superfamily
CRH11_RS01410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRH11_RS01415	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CRH11_RS01420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRH11_RS01425	COG1126	abc transporter atp-binding protein
CRH11_RS01430	COG0765	amino acid transport
CRH11_RS01435	COG0765	amino acid transport
CRH11_RS01440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRH11_RS01445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRH11_RS01450	COG0454	-acetyltransferase
CRH11_RS01455	COG0583	DNA-binding transcription factor activity
CRH11_RS01460	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS01465	COG2732	(Barnase) inhibitor
CRH11_RS01480	COG0557	exoribonuclease II activity
CRH11_RS01485	COG1647	Serine aminopeptidase, S33
CRH11_RS01490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CRH11_RS01495	COG1476	TRANSCRIPTIONal
CRH11_RS01500	COG1396	sequence-specific DNA binding
CRH11_RS01505	COG1396	sequence-specific DNA binding
CRH11_RS01510	COG1733	regulation of RNA biosynthetic process
CRH11_RS01535	COG1131	(ABC) transporter
CRH11_RS01540	COG1174	glycine betaine transport
CRH11_RS01545	COG1732	Glycine betaine
CRH11_RS01550	COG1174	glycine betaine transport
CRH11_RS01555	COG1125	glycine betaine transport
CRH11_RS01555	COG0517	IMP dehydrogenase activity
CRH11_RS01560	COG1510	regulation of RNA biosynthetic process
CRH11_RS01565	COG1174	glycine betaine transport
CRH11_RS01570	COG1732	Glycine betaine
CRH11_RS01575	COG1174	glycine betaine transport
CRH11_RS01580	COG0517	IMP dehydrogenase activity
CRH11_RS01580	COG1125	glycine betaine transport
CRH11_RS01585	COG1510	regulation of RNA biosynthetic process
CRH11_RS01590	COG2095	MarC family integral membrane protein
CRH11_RS01595	COG3064	Membrane
CRH11_RS01600	COG4640	response to antibiotic
CRH11_RS01605	COG0456	acetyltransferase
CRH11_RS01620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CRH11_RS01635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CRH11_RS01640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRH11_RS01645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CRH11_RS01655	COG2234	aminopeptidase activity
CRH11_RS01675	COG0126	phosphoglycerate kinase activity
CRH11_RS01685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CRH11_RS01690	COG2390	Transcriptional regulator
CRH11_RS01695	COG2814	Major facilitator Superfamily
CRH11_RS01700	COG1609	Transcriptional regulator
CRH11_RS01705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRH11_RS01715	COG0583	DNA-binding transcription factor activity
CRH11_RS01720	COG0697	spore germination
CRH11_RS01730	COG1113	amino acid transport
CRH11_RS01740	COG1609	Transcriptional regulator
CRH11_RS01750	COG0561	phosphatase activity
CRH11_RS01755	COG1737	Transcriptional regulator
CRH11_RS01760	COG1070	Carbohydrate kinase
CRH11_RS01785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRH11_RS01790	COG2186	Transcriptional regulator
CRH11_RS01795	COG1620	l-lactate permease
CRH11_RS01800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CRH11_RS01810	COG5039	Polysaccharide pyruvyl transferase
CRH11_RS01815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CRH11_RS01820	COG0110	maltose O-acetyltransferase activity
CRH11_RS01825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CRH11_RS01830	COG2244	polysaccharide biosynthetic process
CRH11_RS01835	COG1216	Glycosyl transferase, family 2
CRH11_RS01840	COG5039	Polysaccharide pyruvyl transferase
CRH11_RS01845	COG1216	Glycosyl transferase, family 2
CRH11_RS01855	COG0438	transferase activity, transferring glycosyl groups
CRH11_RS01860	COG1215	transferase activity, transferring glycosyl groups
CRH11_RS01865	COG0438	transferase activity, transferring glycosyl groups
CRH11_RS01870	COG1086	Polysaccharide biosynthesis protein
CRH11_RS01875	COG0489	protein tyrosine kinase activity
CRH11_RS01880	COG3944	biosynthesis protein
CRH11_RS01885	COG1396	sequence-specific DNA binding
CRH11_RS01890	COG2272	Belongs to the type-B carboxylesterase lipase family
CRH11_RS01900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CRH11_RS01905	COG2364	Membrane
CRH11_RS01910	COG0456	acetyltransferase
CRH11_RS01915	COG3479	Phenolic acid decarboxylase
CRH11_RS01970	COG2223	nitrite transmembrane transporter activity
CRH11_RS01975	COG1609	Transcriptional regulator
CRH11_RS01985	COG0583	DNA-binding transcription factor activity
CRH11_RS01990	COG2828	Protein conserved in bacteria
CRH11_RS01995	COG0477	Major facilitator Superfamily
CRH11_RS01995	COG2814	Major facilitator Superfamily
CRH11_RS02000	COG1611	Belongs to the LOG family
CRH11_RS02005	COG1694	Mazg nucleotide pyrophosphohydrolase
CRH11_RS02010	COG0659	secondary active sulfate transmembrane transporter activity
CRH11_RS02015	COG0288	reversible hydration of carbon dioxide
CRH11_RS02025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRH11_RS02030	COG4290	ribonuclease
CRH11_RS02035	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CRH11_RS02040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRH11_RS02050	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CRH11_RS02060	COG1051	belongs to the nudix hydrolase family
CRH11_RS02065	COG0492	ferredoxin-NADP+ reductase activity
CRH11_RS02070	COG3883	PFAM NLP P60 protein
CRH11_RS02070	COG0791	NLP P60 protein
CRH11_RS02075	COG0457	Tetratricopeptide repeat
CRH11_RS02080	COG5002	protein histidine kinase activity
CRH11_RS02085	COG0745	RESPONSE REGULATOR receiver
CRH11_RS02090	COG1132	(ABC) transporter
CRH11_RS02095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CRH11_RS02095	COG0140	phosphoribosyl-ATP diphosphatase activity
CRH11_RS02120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CRH11_RS02135	COG4990	cell redox homeostasis
CRH11_RS02140	COG0110	maltose O-acetyltransferase activity
CRH11_RS02160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CRH11_RS02170	COG2188	Transcriptional regulator
CRH11_RS02175	COG1309	transcriptional regulator
CRH11_RS02180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CRH11_RS02185	COG1950	PFAM Membrane protein of
CRH11_RS02190	COG1983	PspC domain protein
CRH11_RS02195	COG3595	metallopeptidase activity
CRH11_RS02210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CRH11_RS02220	COG4897	Protein conserved in bacteria
CRH11_RS02225	COG3848	Pyruvate phosphate dikinase
CRH11_RS02225	COG0574	Belongs to the PEP-utilizing enzyme family
CRH11_RS02230	COG1309	transcriptional regulator
CRH11_RS02235	COG2814	Major facilitator Superfamily
CRH11_RS02250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRH11_RS02260	COG0793	Belongs to the peptidase S41A family
CRH11_RS02260	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS02265	COG3420	alginic acid biosynthetic process
CRH11_RS02270	COG2177	Part of the ABC transporter FtsEX involved in
CRH11_RS02275	COG2884	Cell division ATP-binding protein ftsE
CRH11_RS02280	COG2010	Cytochrome c
CRH11_RS02285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRH11_RS02300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CRH11_RS02315	COG1516	flagellar protein fliS
CRH11_RS02320	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CRH11_RS02325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CRH11_RS02345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CRH11_RS02350	COG1256	bacterial-type flagellum assembly
CRH11_RS02350	COG4786	Flagellar basal body rod
CRH11_RS02355	COG3418	PFAM FlgN family protein
CRH11_RS02360	COG2747	anti-sigma28 factor FlgM
CRH11_RS02370	COG1040	competence protein
CRH11_RS02380	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CRH11_RS02385	COG1307	EDD domain protein, DegV family
CRH11_RS02390	COG2197	response regulator
CRH11_RS02395	COG4585	Histidine kinase
CRH11_RS02400	COG1739	Uncharacterized protein family UPF0029
CRH11_RS02405	COG1316	TRANSCRIPTIONal
CRH11_RS02410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CRH11_RS02415	COG0438	transferase activity, transferring glycosyl groups
CRH11_RS02420	COG1215	transferase activity, transferring glycosyl groups
CRH11_RS02425	COG3206	protein involved in exopolysaccharide biosynthesis
CRH11_RS02430	COG3307	-O-antigen
CRH11_RS02435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CRH11_RS02440	COG0438	transferase activity, transferring glycosyl groups
CRH11_RS02440	COG0297	glycogen (starch) synthase activity
CRH11_RS02445	COG2244	polysaccharide biosynthetic process
CRH11_RS02455	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS02455	COG2247	cell wall binding repeat
CRH11_RS02460	COG2385	sporulation resulting in formation of a cellular spore
CRH11_RS02460	COG2247	cell wall binding repeat
CRH11_RS02470	COG1316	TRANSCRIPTIONal
CRH11_RS02475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CRH11_RS02480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CRH11_RS02485	COG1134	teichoic acid transport
CRH11_RS02490	COG1682	transport, permease protein
CRH11_RS02495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CRH11_RS02505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CRH11_RS02510	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CRH11_RS02515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CRH11_RS02520	COG4193	domain, Protein
CRH11_RS02525	COG1482	cell wall glycoprotein biosynthetic process
CRH11_RS02530	COG0697	spore germination
CRH11_RS02535	COG0814	amino acid
CRH11_RS02545	COG1215	transferase activity, transferring glycosyl groups
CRH11_RS02550	COG2814	Major facilitator Superfamily
CRH11_RS02555	COG1316	TRANSCRIPTIONal
CRH11_RS02560	COG0561	phosphatase activity
CRH11_RS02570	COG0791	NLP P60 protein
CRH11_RS02580	COG2843	Capsule synthesis protein
CRH11_RS02590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CRH11_RS02600	COG0697	spore germination
CRH11_RS02605	COG0814	amino acid
CRH11_RS02615	COG1609	Transcriptional regulator
CRH11_RS02620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRH11_RS02630	COG1129	ABC transporter
CRH11_RS02635	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRH11_RS02640	COG1879	ABC-type sugar transport system periplasmic component
CRH11_RS02645	COG3103	Sh3 type 3 domain protein
CRH11_RS02650	COG2249	NAD(P)H dehydrogenase (quinone) activity
CRH11_RS02655	COG3527	Alpha-acetolactate decarboxylase
CRH11_RS02660	COG0028	Belongs to the TPP enzyme family
CRH11_RS02665	COG0583	DNA-binding transcription factor activity
CRH11_RS02670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CRH11_RS02685	COG5337	Spore coat protein CotH
CRH11_RS02695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CRH11_RS02705	COG0405	Gamma-glutamyltransferase
CRH11_RS02710	COG1522	sequence-specific DNA binding
CRH11_RS02715	COG2059	Chromate
CRH11_RS02720	COG2059	Chromate
CRH11_RS02760	COG5444	nuclease activity
CRH11_RS02775	COG3878	Protein conserved in bacteria
CRH11_RS02780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CRH11_RS02785	COG4464	protein tyrosine phosphatase activity
CRH11_RS02790	COG0489	protein tyrosine kinase activity
CRH11_RS02795	COG3944	biosynthesis protein
CRH11_RS02810	COG4715	Zinc finger, swim domain protein
CRH11_RS02815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CRH11_RS02820	COG0561	phosphatase activity
CRH11_RS02825	COG1349	DNA-binding transcription factor activity
CRH11_RS02830	COG0629	single-stranded DNA binding
CRH11_RS02855	COG0457	Tetratricopeptide repeat
CRH11_RS02860	COG4786	Flagellar basal body rod
CRH11_RS02865	COG4786	Flagellar basal body rod
CRH11_RS02870	COG1077	Cell shape determining protein MreB Mrl
CRH11_RS02875	COG1609	Transcriptional regulator
CRH11_RS02880	COG1846	Transcriptional regulator
CRH11_RS02885	COG2814	Major facilitator Superfamily
CRH11_RS02890	COG1953	Uracil, thiamine, allantoin
CRH11_RS02895	COG0477	Major facilitator Superfamily
CRH11_RS02900	COG1335	isochorismatase
CRH11_RS02905	COG0004	ammonium transporteR
CRH11_RS02910	COG0347	Belongs to the P(II) protein family
CRH11_RS02915	COG0772	Belongs to the SEDS family
CRH11_RS02920	COG0671	phosphoesterase, PA-phosphatase related
CRH11_RS02930	COG0739	heme binding
CRH11_RS02935	COG1247	-acetyltransferase
CRH11_RS02950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRH11_RS02965	COG0726	polysaccharide deacetylase
CRH11_RS02975	COG1959	2 iron, 2 sulfur cluster binding
CRH11_RS02990	COG0831	urea catabolic process
CRH11_RS02995	COG3237	CsbD-like
CRH11_RS03000	COG1994	Peptidase M50
CRH11_RS03005	COG0457	Tetratricopeptide repeat
CRH11_RS03015	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CRH11_RS03025	COG2304	oxidoreductase activity
CRH11_RS03030	COG2304	oxidoreductase activity
CRH11_RS03040	COG2385	sporulation resulting in formation of a cellular spore
CRH11_RS03045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CRH11_RS03055	COG4836	Membrane
CRH11_RS03125	COG0698	ribose 5-phosphate isomerase
CRH11_RS03130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CRH11_RS03140	COG0009	L-threonylcarbamoyladenylate synthase
CRH11_RS03145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CRH11_RS03165	COG2890	protein-(glutamine-N5) methyltransferase activity
CRH11_RS03170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CRH11_RS03175	COG0346	lactoylglutathione lyase activity
CRH11_RS03180	COG0789	Transcriptional regulator
CRH11_RS03185	COG0679	Auxin Efflux Carrier
CRH11_RS03190	COG0281	malic enzyme
CRH11_RS03205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CRH11_RS03210	COG1494	fructose-1,6-bisphosphatase
CRH11_RS03215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CRH11_RS03225	COG0191	fructose-bisphosphate aldolase activity
CRH11_RS03230	COG2204	response regulator
CRH11_RS03235	COG4821	SIS domain
CRH11_RS03250	COG2181	nitrate reductase activity
CRH11_RS03250	COG0247	lactate metabolic process
CRH11_RS03255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRH11_RS03270	COG1132	(ABC) transporter
CRH11_RS03275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRH11_RS03285	COG2181	nitrate reductase activity
CRH11_RS03290	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CRH11_RS03295	COG1140	nitrate reductase beta subunit
CRH11_RS03300	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CRH11_RS03305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CRH11_RS03315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CRH11_RS03320	COG2223	nitrite transmembrane transporter activity
CRH11_RS03330	COG4506	Protein conserved in bacteria
CRH11_RS03340	COG3391	amine dehydrogenase activity
CRH11_RS03345	COG3391	amine dehydrogenase activity
CRH11_RS03355	COG0457	Tetratricopeptide repeat
CRH11_RS03400	COG0010	Belongs to the arginase family
CRH11_RS03405	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CRH11_RS03410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRH11_RS03425	COG1994	Peptidase M50
CRH11_RS03430	COG1942	4-Oxalocrotonate Tautomerase
CRH11_RS03435	COG1846	Transcriptional regulator
CRH11_RS03445	COG0531	amino acid
CRH11_RS03450	COG3465	dGTPase activity
CRH11_RS03455	COG1078	dGTPase activity
CRH11_RS03470	COG1695	Transcriptional regulator
CRH11_RS03480	COG1131	(ABC) transporter
CRH11_RS03485	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CRH11_RS03515	COG0583	DNA-binding transcription factor activity
CRH11_RS03520	COG2855	membrane
CRH11_RS03525	COG0280	phosphate acetyltransferase
CRH11_RS03535	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS03540	COG0436	Aminotransferase
CRH11_RS03570	COG2814	Major facilitator Superfamily
CRH11_RS03575	COG2814	Major facilitator Superfamily
CRH11_RS03580	COG0833	amino acid
CRH11_RS03585	COG4187	Peptidase family M20/M25/M40
CRH11_RS03590	COG1012	belongs to the aldehyde dehydrogenase family
CRH11_RS03595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CRH11_RS03600	COG2205	protein histidine kinase activity
CRH11_RS03605	COG0745	RESPONSE REGULATOR receiver
CRH11_RS03620	COG1131	(ABC) transporter
CRH11_RS03625	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CRH11_RS03630	COG1091	dTDP-4-dehydrorhamnose reductase activity
CRH11_RS03635	COG1088	dTDP-glucose 4,6-dehydratase activity
CRH11_RS03640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CRH11_RS03645	COG3980	spore coat polysaccharide biosynthesis protein
CRH11_RS03650	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CRH11_RS03655	COG2089	acid synthase
CRH11_RS03660	COG0456	acetyltransferase
CRH11_RS03665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CRH11_RS03670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CRH11_RS03675	COG0463	Glycosyl transferase, family 2
CRH11_RS03685	COG2363	Small membrane protein
CRH11_RS03690	COG2233	PERMEase
CRH11_RS03705	COG1216	Glycosyl transferase, family 2
CRH11_RS03720	COG1695	Transcriptional regulator
CRH11_RS03725	COG0351	phosphomethylpyrimidine kinase
CRH11_RS03735	COG1621	beta-fructofuranosidase activity
CRH11_RS03740	COG1263	PTS System
CRH11_RS03740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRH11_RS03745	COG3711	transcriptional antiterminator
CRH11_RS03755	COG1404	Belongs to the peptidase S8 family
CRH11_RS03760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRH11_RS03765	COG0778	Nitroreductase
CRH11_RS03770	COG0772	Belongs to the SEDS family
CRH11_RS03775	COG0454	-acetyltransferase
CRH11_RS03795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CRH11_RS03800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CRH11_RS03805	COG2261	transglycosylase associated protein
CRH11_RS03810	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CRH11_RS03815	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CRH11_RS03820	COG2246	polysaccharide biosynthetic process
CRH11_RS03825	COG1309	transcriptional regulator
CRH11_RS03845	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CRH11_RS03850	COG2837	iron assimilation
CRH11_RS03855	COG2822	iron ion transport
CRH11_RS03870	COG0583	DNA-binding transcription factor activity
CRH11_RS03880	COG1346	cytolysis
CRH11_RS03885	COG1131	(ABC) transporter
CRH11_RS03915	COG4895	conserved protein (DUF2196)
CRH11_RS03920	COG0789	Transcriptional regulator
CRH11_RS03925	COG5504	Zn-dependent protease
CRH11_RS03930	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CRH11_RS03935	COG0346	lactoylglutathione lyase activity
CRH11_RS03940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRH11_RS03945	COG1404	Belongs to the peptidase S8 family
CRH11_RS03950	COG1442	glycosyl transferase family 8
CRH11_RS03960	COG2357	RelA SpoT domain protein
CRH11_RS03965	COG1575	Belongs to the MenA family. Type 1 subfamily
CRH11_RS03985	COG1696	Membrane protein involved in D-alanine export
CRH11_RS03995	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CRH11_RS04000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRH11_RS04005	COG1486	melibiose metabolic process
CRH11_RS04010	COG1447	Phosphotransferase system cellobiose-specific component IIA
CRH11_RS04015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRH11_RS04020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRH11_RS04025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRH11_RS04025	COG3711	transcriptional antiterminator
CRH11_RS04040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRH11_RS04045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRH11_RS04055	COG0640	Transcriptional regulator
CRH11_RS04060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CRH11_RS04065	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRH11_RS04070	COG1447	Phosphotransferase system cellobiose-specific component IIA
CRH11_RS04075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRH11_RS04080	COG2723	6-phospho-beta-galactosidase activity
CRH11_RS04085	COG1940	carbohydrate kinase activity
CRH11_RS04090	COG1482	cell wall glycoprotein biosynthetic process
CRH11_RS04100	COG0753	catalase activity
CRH11_RS04105	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CRH11_RS04110	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CRH11_RS04115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CRH11_RS04120	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CRH11_RS04125	COG4988	ABC transporter
CRH11_RS04130	COG1294	oxidase, subunit
CRH11_RS04135	COG1271	oxidase subunit
CRH11_RS04140	COG3493	citrate carrier protein
CRH11_RS04145	COG0726	polysaccharide deacetylase
CRH11_RS04150	COG3842	ATPase activity
CRH11_RS04155	COG2508	Transcriptional regulator
CRH11_RS04160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRH11_RS04170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CRH11_RS04180	COG4894	glucomannan catabolic process
CRH11_RS04185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CRH11_RS04190	COG0500	methyltransferase
CRH11_RS04195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRH11_RS04210	COG0753	catalase activity
CRH11_RS04210	COG0693	protein deglycase activity
CRH11_RS04215	COG2851	Citrate transporter
CRH11_RS04220	COG2273	Hydrolase Family 16
CRH11_RS04225	COG3711	transcriptional antiterminator
CRH11_RS04230	COG2270	Major facilitator Superfamily
CRH11_RS04235	COG0513	Belongs to the DEAD box helicase family
CRH11_RS04260	COG3209	COG3209 Rhs family protein
CRH11_RS04270	COG0697	spore germination
CRH11_RS04275	COG0589	response to stress
CRH11_RS04325	COG3507	Belongs to the glycosyl hydrolase 43 family
CRH11_RS04350	COG0010	Belongs to the arginase family
CRH11_RS04355	COG0833	amino acid
CRH11_RS04360	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CRH11_RS04365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRH11_RS04375	COG2390	Transcriptional regulator
CRH11_RS04380	COG0561	phosphatase activity
CRH11_RS04410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRH11_RS04415	COG5294	Protein conserved in bacteria
CRH11_RS04420	COG0577	efflux transmembrane transporter activity
CRH11_RS04425	COG1136	(ABC) transporter
CRH11_RS04430	COG2205	protein histidine kinase activity
CRH11_RS04435	COG0745	RESPONSE REGULATOR receiver
CRH11_RS04450	COG1082	Xylose isomerase domain protein TIM barrel
CRH11_RS04460	COG2814	Major facilitator Superfamily
CRH11_RS04490	COG1349	DNA-binding transcription factor activity
CRH11_RS04495	COG0667	Aldo Keto reductase
CRH11_RS04500	COG2814	Major facilitator Superfamily
CRH11_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS04520	COG2197	response regulator
CRH11_RS04525	COG4585	Histidine kinase
CRH11_RS04530	COG3239	Fatty acid desaturase
CRH11_RS04540	COG1309	transcriptional regulator
CRH11_RS04545	COG1012	belongs to the aldehyde dehydrogenase family
CRH11_RS04550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CRH11_RS04560	COG0640	Transcriptional regulator
CRH11_RS04565	COG2814	Major facilitator Superfamily
CRH11_RS04570	COG1714	RDD family
CRH11_RS04580	COG0450	alkyl hydroperoxide reductase
CRH11_RS04585	COG3634	alkyl hydroperoxide reductase activity
CRH11_RS04590	COG3177	Filamentation induced by cAMP protein fic
CRH11_RS04595	COG1113	amino acid transport
CRH11_RS04605	COG2080	2 iron, 2 sulfur cluster binding
CRH11_RS04620	COG2068	MobA-Related Protein
CRH11_RS04625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CRH11_RS04640	COG1715	Restriction endonuclease
CRH11_RS04675	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CRH11_RS04680	COG0667	Aldo Keto reductase
CRH11_RS04685	COG0456	acetyltransferase
CRH11_RS04690	COG0457	Tetratricopeptide repeat
CRH11_RS04695	COG0010	Belongs to the arginase family
CRH11_RS04700	COG0833	amino acid
CRH11_RS04705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CRH11_RS04710	COG5658	integral membrane protein
CRH11_RS04715	COG0640	Transcriptional regulator
CRH11_RS04720	COG3829	transcription factor binding
CRH11_RS04730	COG0488	(ABC) transporter
CRH11_RS04745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CRH11_RS04750	COG3850	Histidine kinase
CRH11_RS04750	COG5002	protein histidine kinase activity
CRH11_RS04755	COG0745	RESPONSE REGULATOR receiver
CRH11_RS04760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRH11_RS04765	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CRH11_RS04770	COG4853	Protein conserved in bacteria
CRH11_RS04775	COG4863	YycH protein
CRH11_RS04780	COG5002	protein histidine kinase activity
CRH11_RS04785	COG0745	RESPONSE REGULATOR receiver
CRH11_RS04820	COG0346	lactoylglutathione lyase activity
CRH11_RS04825	COG0305	Participates in initiation and elongation during chromosome replication
CRH11_RS04845	COG3093	addiction module antidote protein HigA
CRH11_RS04850	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CRH11_RS04865	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CRH11_RS04870	COG0438	transferase activity, transferring glycosyl groups
CRH11_RS04895	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CRH11_RS04900	COG4241	membrane
CRH11_RS04910	COG5577	PFAM Coat F domain
CRH11_RS04915	COG1733	regulation of RNA biosynthetic process
CRH11_RS04925	COG0697	spore germination
CRH11_RS04930	COG1621	beta-fructofuranosidase activity
CRH11_RS04935	COG1621	beta-fructofuranosidase activity
CRH11_RS04940	COG1802	Transcriptional regulator
CRH11_RS04945	COG2318	DinB family
CRH11_RS04950	COG2211	Major facilitator Superfamily
CRH11_RS04955	COG0583	DNA-binding transcription factor activity
CRH11_RS04970	COG0778	Nitroreductase
CRH11_RS04975	COG1846	Transcriptional regulator
CRH11_RS04980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRH11_RS04985	COG1846	Transcriptional regulator
CRH11_RS04990	COG2153	protein acetylation
CRH11_RS05000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CRH11_RS05005	COG0583	DNA-binding transcription factor activity
CRH11_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS05015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRH11_RS05020	COG0697	spore germination
CRH11_RS05025	COG1331	Highly conserved protein containing a thioredoxin domain
CRH11_RS05035	COG0457	Tetratricopeptide repeat
CRH11_RS05055	COG0791	NLP P60 protein
CRH11_RS05055	COG0741	lytic transglycosylase activity
CRH11_RS05060	COG5644	endopeptidase inhibitor activity
CRH11_RS05070	COG0433	COG0433 Predicted ATPase
CRH11_RS05105	COG2946	Replication initiation factor
CRH11_RS05110	COG1674	ftsk spoiiie
CRH11_RS05135	COG1396	sequence-specific DNA binding
CRH11_RS05140	COG2856	Zn peptidase
CRH11_RS05145	COG1331	Highly conserved protein containing a thioredoxin domain
CRH11_RS05150	COG1331	Highly conserved protein containing a thioredoxin domain
CRH11_RS05155	COG1266	CAAX protease self-immunity
CRH11_RS05160	COG2814	Major facilitator Superfamily
CRH11_RS05160	COG0477	Major facilitator Superfamily
CRH11_RS05165	COG0346	lactoylglutathione lyase activity
CRH11_RS05170	COG1609	Transcriptional regulator
CRH11_RS05175	COG0708	Exodeoxyribonuclease III
CRH11_RS05180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CRH11_RS05185	COG2169	Transcriptional regulator
CRH11_RS05195	COG0629	single-stranded DNA binding
CRH11_RS05205	COG0012	GTP binding
CRH11_RS05210	COG0243	molybdopterin cofactor binding
CRH11_RS05215	COG4481	Protein conserved in bacteria
CRH11_RS05220	COG3949	Membrane
CRH11_RS05235	COG1475	DNA binding
CRH11_RS05240	COG1192	Involved in chromosome partitioning
CRH11_RS05265	COG1847	R3H domain protein
CRH11_RS05270	COG0706	membrane insertase activity
CRH11_RS05290	COG0592	DNA-directed DNA polymerase activity
CRH11_RS05295	COG2501	S4 domain
CRH11_RS05310	COG0187	DNA topoisomerase II activity
CRH11_RS05315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CRH11_RS05350	COG0517	IMP dehydrogenase activity
CRH11_RS05350	COG0516	GMP reductase activity
CRH11_RS05355	COG1686	Belongs to the peptidase S11 family
CRH11_RS05375	COG1929	Belongs to the glycerate kinase type-1 family
CRH11_RS05385	COG1428	Deoxynucleoside kinase
CRH11_RS05390	COG1428	Deoxynucleoside kinase
CRH11_RS05395	COG1388	LysM domain
CRH11_RS05395	COG3858	chitin binding
CRH11_RS05400	COG1335	isochorismatase
CRH11_RS05405	COG0590	tRNA wobble adenosine to inosine editing
CRH11_RS05415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CRH11_RS05420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CRH11_RS05470	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CRH11_RS05475	COG3853	Toxic anion resistance protein (TelA)
CRH11_RS05480	COG1982	Orn Lys Arg decarboxylase major
CRH11_RS05490	COG3870	Protein conserved in bacteria
CRH11_RS05495	COG1728	Protein conserved in bacteria
CRH11_RS05500	COG0470	DNA polymerase III
CRH11_RS05505	COG1774	PSP1 C-terminal conserved region
CRH11_RS05515	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CRH11_RS05525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CRH11_RS05530	COG2002	toxin-antitoxin pair type II binding
CRH11_RS05535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRH11_RS05535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRH11_RS05540	COG0084	hydrolase, TatD family'
CRH11_RS05545	COG3584	3D domain protein
CRH11_RS05545	COG3583	domain protein
CRH11_RS05550	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CRH11_RS05555	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CRH11_RS05565	COG4466	Protein conserved in bacteria
CRH11_RS05580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CRH11_RS05585	COG0251	oxidation-reduction process
CRH11_RS05600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CRH11_RS05620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CRH11_RS05625	COG2002	toxin-antitoxin pair type II binding
CRH11_RS05630	COG2244	polysaccharide biosynthetic process
CRH11_RS05635	COG3956	TIGRFAM MazG family protein
CRH11_RS05640	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CRH11_RS05655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CRH11_RS05660	COG1098	S1 RNA binding domain
CRH11_RS05675	COG2208	phosphoserine phosphatase activity
CRH11_RS05680	COG2304	oxidoreductase activity
CRH11_RS05685	COG0515	serine threonine protein kinase
CRH11_RS05690	COG0037	tRNA processing
CRH11_RS05695	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CRH11_RS05700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CRH11_RS05715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRH11_RS05720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CRH11_RS05725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CRH11_RS05730	COG0512	Glutamine amidotransferase of anthranilate synthase
CRH11_RS05735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRH11_RS05740	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CRH11_RS05745	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CRH11_RS05750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CRH11_RS05755	COG1396	sequence-specific DNA binding
CRH11_RS05760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRH11_RS05765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CRH11_RS05850	COG4463	regulation of RNA biosynthetic process
CRH11_RS05855	COG3880	PFAM UvrB UvrC protein
CRH11_RS05865	COG0542	response to heat
CRH11_RS05870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CRH11_RS05875	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CRH11_RS05880	COG4956	integral membrane protein (PIN domain superfamily)
CRH11_RS05900	COG1045	serine acetyltransferase
CRH11_RS05910	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CRH11_RS05915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CRH11_RS05920	COG3688	RNA-binding protein containing a PIN domain
CRH11_RS05925	COG1595	DNA-templated transcription, initiation
CRH11_RS05935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CRH11_RS05940	COG0250	Participates in transcription elongation, termination and antitermination
CRH11_RS05965	COG2813	Specifically methylates the guanine in position
CRH11_RS05980	COG1358	cellular component organization or biogenesis
CRH11_RS06005	COG0596	Alpha beta hydrolase
CRH11_RS06115	COG0201	protein transport
CRH11_RS06125	COG0024	Methionine aminopeptidase
CRH11_RS06140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CRH11_RS06165	COG1122	ATPase activity
CRH11_RS06170	COG1122	ATPase activity
CRH11_RS06175	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CRH11_RS06195	COG2226	methyltransferase
CRH11_RS06200	COG2318	DinB family
CRH11_RS06210	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS06215	COG0489	protein tyrosine kinase activity
CRH11_RS06225	COG2194	sulfuric ester hydrolase activity
CRH11_RS06230	COG0726	polysaccharide deacetylase
CRH11_RS06290	COG0738	Major facilitator superfamily
CRH11_RS06295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CRH11_RS06310	COG0659	secondary active sulfate transmembrane transporter activity
CRH11_RS06315	COG0385	Bile acid
CRH11_RS06320	COG2819	hydrolase of the alpha beta superfamily
CRH11_RS06325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRH11_RS06330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRH11_RS06335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRH11_RS06340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRH11_RS06340	COG2207	Transcriptional regulator
CRH11_RS06345	COG3876	Protein conserved in bacteria
CRH11_RS06350	COG1472	Belongs to the glycosyl hydrolase 3 family
CRH11_RS06355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CRH11_RS06360	COG1263	PTS System
CRH11_RS06360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRH11_RS06370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRH11_RS06375	COG1683	Conserved Protein
CRH11_RS06405	COG1595	DNA-templated transcription, initiation
CRH11_RS06410	COG5662	AntiSigma factor
CRH11_RS06415	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CRH11_RS06420	COG4856	YbbR-like protein
CRH11_RS06470	COG1346	cytolysis
CRH11_RS06475	COG1380	Effector of murein hydrolase LrgA
CRH11_RS06480	COG1846	Transcriptional regulator
CRH11_RS06485	COG1113	amino acid transport
CRH11_RS06490	COG1011	Hydrolase
CRH11_RS06495	COG4585	Histidine kinase
CRH11_RS06500	COG2197	response regulator
CRH11_RS06505	COG1131	(ABC) transporter
CRH11_RS06545	COG0531	amino acid
CRH11_RS06560	COG0584	glycerophosphoryl diester phosphodiesterase
CRH11_RS06565	COG2271	Major facilitator Superfamily
CRH11_RS06580	COG2368	4-hydroxyphenylacetate
CRH11_RS06590	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS06605	COG0371	Dehydrogenase
CRH11_RS06615	COG1183	phosphatidylcholine synthase activity
CRH11_RS06620	COG0586	Pfam SNARE associated Golgi protein
CRH11_RS06625	COG0688	phosphatidylethanolamine metabolic process
CRH11_RS06640	COG1301	dicarboxylic acid transport
CRH11_RS06645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRH11_RS06650	COG0833	amino acid
CRH11_RS06655	COG2040	homocysteine
CRH11_RS06660	COG1115	amino acid carrier protein
CRH11_RS06665	COG2066	Belongs to the glutaminase family
CRH11_RS06670	COG4191	Histidine kinase
CRH11_RS06675	COG0784	Response regulator, receiver
CRH11_RS06680	COG3173	Aminoglycoside phosphotransferase
CRH11_RS06695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CRH11_RS06700	COG0778	Nitroreductase
CRH11_RS06705	COG0346	lactoylglutathione lyase activity
CRH11_RS06710	COG2259	Doxx family
CRH11_RS06715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRH11_RS06730	COG3773	Cell wall hydrolase
CRH11_RS06740	COG3540	Alkaline phosphatase
CRH11_RS06745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CRH11_RS06750	COG0805	protein transport
CRH11_RS06760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CRH11_RS06765	COG0477	Major facilitator Superfamily
CRH11_RS06770	COG1309	transcriptional regulator
CRH11_RS06775	COG0252	asparaginase activity
CRH11_RS06780	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CRH11_RS06785	COG1405	negative regulation of cell septum assembly
CRH11_RS06785	COG3012	SEC-C Motif Domain Protein
CRH11_RS06790	COG0667	Aldo Keto reductase
CRH11_RS06800	COG1595	DNA-templated transcription, initiation
CRH11_RS06805	COG1595	DNA-templated transcription, initiation
CRH11_RS06810	COG1876	peptidase activity
CRH11_RS06815	COG0457	Tetratricopeptide repeat
CRH11_RS06820	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS06825	COG0366	Alpha amylase catalytic
CRH11_RS06830	COG0803	Belongs to the bacterial solute-binding protein 9 family
CRH11_RS06835	COG1121	(ABC) transporter
CRH11_RS06840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRH11_RS06845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRH11_RS06850	COG2310	stress, protein
CRH11_RS06855	COG2310	stress, protein
CRH11_RS06860	COG2310	stress, protein
CRH11_RS06865	COG0861	Integral membrane protein TerC family
CRH11_RS06875	COG3853	Toxic anion resistance protein (TelA)
CRH11_RS06880	COG0477	Major facilitator Superfamily
CRH11_RS06885	COG0517	IMP dehydrogenase activity
CRH11_RS06885	COG4175	Glycine betaine
CRH11_RS06890	COG4176	ABC-type proline glycine betaine transport system permease component
CRH11_RS06895	COG2113	Glycine betaine
CRH11_RS06900	COG1473	amidohydrolase
CRH11_RS06905	COG1288	antiporter activity
CRH11_RS06915	COG0366	Alpha amylase catalytic
CRH11_RS06925	COG2814	Major facilitator Superfamily
CRH11_RS06930	COG1846	Transcriptional regulator
CRH11_RS06935	COG1280	lysine exporter protein (LysE YggA)
CRH11_RS06940	COG3403	YqcI/YcgG family
CRH11_RS06945	COG1113	amino acid transport
CRH11_RS06950	COG3665	Urea carboxylase-associated protein
CRH11_RS06965	COG1660	Displays ATPase and GTPase activities
CRH11_RS06975	COG2271	Major facilitator Superfamily
CRH11_RS06980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CRH11_RS06985	COG3458	cephalosporin-C deacetylase activity
CRH11_RS06990	COG3541	Predicted nucleotidyltransferase
CRH11_RS06995	COG0506	proline dehydrogenase activity
CRH11_RS07000	COG1012	belongs to the aldehyde dehydrogenase family
CRH11_RS07005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRH11_RS07010	COG2508	Transcriptional regulator
CRH11_RS07020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CRH11_RS07020	COG1587	Uroporphyrinogen-III synthase
CRH11_RS07025	COG2146	nitrite reductase [NAD(P)H] activity
CRH11_RS07030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CRH11_RS07035	COG0243	molybdopterin cofactor binding
CRH11_RS07040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CRH11_RS07045	COG2223	nitrite transmembrane transporter activity
CRH11_RS07050	COG0523	cobalamin synthesis protein
CRH11_RS07055	COG1063	alcohol dehydrogenase
CRH11_RS07060	COG1714	RDD family
CRH11_RS07070	COG2723	6-phospho-beta-galactosidase activity
CRH11_RS07080	COG3209	COG3209 Rhs family protein
CRH11_RS07085	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CRH11_RS07090	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CRH11_RS07095	COG1733	regulation of RNA biosynthetic process
CRH11_RS07105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS07110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS07115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS07120	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CRH11_RS07135	COG0697	spore germination
CRH11_RS07140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRH11_RS07150	COG2364	Membrane
CRH11_RS07155	COG1126	abc transporter atp-binding protein
CRH11_RS07160	COG0765	amino acid transport
CRH11_RS07165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRH11_RS07170	COG0583	DNA-binding transcription factor activity
CRH11_RS07175	COG0163	prenyltransferase activity
CRH11_RS07180	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CRH11_RS07200	COG3104	oligopeptide transport
CRH11_RS07205	COG5434	Belongs to the glycosyl hydrolase 28 family
CRH11_RS07215	COG0697	spore germination
CRH11_RS07225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CRH11_RS07230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRH11_RS07235	COG0456	acetyltransferase
CRH11_RS07240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRH11_RS07245	COG0765	amino acid transport
CRH11_RS07250	COG1126	abc transporter atp-binding protein
CRH11_RS07255	COG1473	amidohydrolase
CRH11_RS07260	COG2079	MmgE PrpD family protein
CRH11_RS07265	COG1136	(ABC) transporter
CRH11_RS07270	COG0577	efflux transmembrane transporter activity
CRH11_RS07275	COG0745	RESPONSE REGULATOR receiver
CRH11_RS07280	COG3850	Histidine kinase
CRH11_RS07280	COG5002	protein histidine kinase activity
CRH11_RS07285	COG0457	Tetratricopeptide repeat
CRH11_RS07300	COG0527	aspartate kinase activity
CRH11_RS07305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRH11_RS07310	COG4605	iron ion homeostasis
CRH11_RS07315	COG4604	ABC transporter, ATP-binding protein
CRH11_RS07320	COG4607	ABC-type enterochelin transport system periplasmic component
CRH11_RS07325	COG2814	Major facilitator Superfamily
CRH11_RS07330	COG1309	transcriptional regulator
CRH11_RS07335	COG0778	Nitroreductase
CRH11_RS07340	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CRH11_RS07345	COG0640	Transcriptional regulator
CRH11_RS07350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRH11_RS07355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CRH11_RS07360	COG1012	belongs to the aldehyde dehydrogenase family
CRH11_RS07365	COG4975	Glucose uptake
CRH11_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS07375	COG4549	nuclear export factor GLE1
CRH11_RS07380	COG1276	copper resistance
CRH11_RS07380	COG2372	response to copper ion
CRH11_RS07385	COG1349	DNA-binding transcription factor activity
CRH11_RS07395	COG2213	PTS system mannitol-specific
CRH11_RS07400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRH11_RS07410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CRH11_RS07420	COG0561	phosphatase activity
CRH11_RS07430	COG1914	H( )-stimulated, divalent metal cation uptake system
CRH11_RS07440	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CRH11_RS07445	COG1984	allophanate hydrolase subunit 2
CRH11_RS07450	COG1414	Transcriptional regulator
CRH11_RS07455	COG2755	lipolytic protein G-D-S-L family
CRH11_RS07465	COG2329	Antibiotic biosynthesis monooxygenase
CRH11_RS07470	COG0768	penicillin binding
CRH11_RS07475	COG4989	oxidoreductase activity
CRH11_RS07480	COG3711	transcriptional antiterminator
CRH11_RS07485	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS07490	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS07495	COG1917	Cupin 2, conserved barrel domain protein
CRH11_RS07500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRH11_RS07505	COG3871	stress protein (general stress protein 26)
CRH11_RS07515	COG2814	Major facilitator Superfamily
CRH11_RS07520	COG1522	sequence-specific DNA binding
CRH11_RS07525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CRH11_RS07525	COG0551	DNA topoisomerase type I activity
CRH11_RS07530	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CRH11_RS07535	COG3706	GGDEF domain
CRH11_RS07540	COG5298	Protein conserved in bacteria
CRH11_RS07545	COG1215	transferase activity, transferring glycosyl groups
CRH11_RS07555	COG0531	amino acid
CRH11_RS07560	COG0494	nUDIX hydrolase
CRH11_RS07565	COG0028	Belongs to the TPP enzyme family
CRH11_RS07590	COG0457	Tetratricopeptide repeat
CRH11_RS07620	COG1914	H( )-stimulated, divalent metal cation uptake system
CRH11_RS07635	COG4876	unkown
CRH11_RS07645	COG2076	Multidrug Resistance protein
CRH11_RS07650	COG2217	Heavy metal translocating P-type atpase
CRH11_RS07655	COG3729	General stress protein
CRH11_RS07660	COG0662	Cupin 2, conserved barrel domain protein
CRH11_RS07665	COG2329	Antibiotic biosynthesis monooxygenase
CRH11_RS07670	COG3546	catalase activity
CRH11_RS07675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CRH11_RS07680	COG3290	protein histidine kinase activity
CRH11_RS07685	COG4565	transcriptional regulatory protein
CRH11_RS07690	COG1301	dicarboxylic acid transport
CRH11_RS07695	COG0628	permease
CRH11_RS07700	COG1131	(ABC) transporter
CRH11_RS07705	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CRH11_RS07715	COG1960	acyl-CoA dehydrogenase activity
CRH11_RS07730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CRH11_RS07735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRH11_RS07745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CRH11_RS07750	COG0513	Belongs to the DEAD box helicase family
CRH11_RS07755	COG3402	PFAM membrane-flanked domain
CRH11_RS07760	COG3428	Bacterial PH domain
CRH11_RS07765	COG0705	Rhomboid family
CRH11_RS07775	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CRH11_RS07780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CRH11_RS07785	COG0864	Transcriptional regulator
CRH11_RS07790	COG2337	Toxic component of a toxin-antitoxin (TA) module
CRH11_RS07795	COG1366	Belongs to the anti-sigma-factor antagonist family
CRH11_RS07800	COG1366	Belongs to the anti-sigma-factor antagonist family
CRH11_RS07805	COG2172	sigma factor antagonist activity
CRH11_RS07810	COG2208	phosphoserine phosphatase activity
CRH11_RS07815	COG1366	Belongs to the anti-sigma-factor antagonist family
CRH11_RS07825	COG1191	sigma factor activity
CRH11_RS07830	COG2208	phosphoserine phosphatase activity
CRH11_RS07835	COG2183	response to ionizing radiation
CRH11_RS07890	COG1959	2 iron, 2 sulfur cluster binding
CRH11_RS07895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CRH11_RS07900	COG1090	epimerase
CRH11_RS07905	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CRH11_RS07920	COG2249	NAD(P)H dehydrogenase (quinone) activity
CRH11_RS07925	COG0457	Tetratricopeptide repeat
CRH11_RS07945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CRH11_RS07950	COG0477	Major facilitator Superfamily
CRH11_RS07955	COG1846	Transcriptional regulator
CRH11_RS07965	COG2030	dehydratase
CRH11_RS07980	COG1959	2 iron, 2 sulfur cluster binding
CRH11_RS07985	COG2910	NAD(P)H-binding
CRH11_RS07990	COG1309	transcriptional regulator
CRH11_RS07995	COG0300	oxidoreductase activity
CRH11_RS08005	COG0604	alcohol dehydrogenase
CRH11_RS08015	COG3239	Fatty acid desaturase
CRH11_RS08020	COG1278	Cold shock
CRH11_RS08025	COG1329	Transcriptional regulator
CRH11_RS08030	COG1937	Protein conserved in bacteria
CRH11_RS08035	COG2210	Belongs to the sulfur carrier protein TusA family
CRH11_RS08040	COG1054	Belongs to the UPF0176 family
CRH11_RS08045	COG0425	Belongs to the sulfur carrier protein TusA family
CRH11_RS08045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRH11_RS08050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRH11_RS08050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRH11_RS08055	COG0425	Belongs to the sulfur carrier protein TusA family
CRH11_RS08060	COG0730	response to heat
CRH11_RS08065	COG1794	racemase activity, acting on amino acids and derivatives
CRH11_RS08080	COG3621	Patatin-like phospholipase
CRH11_RS08090	COG0662	Cupin 2, conserved barrel domain protein
CRH11_RS08105	COG0277	FAD linked oxidase domain protein
CRH11_RS08130	COG0662	Cupin 2, conserved barrel domain protein
CRH11_RS08135	COG2318	DinB family
CRH11_RS08140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CRH11_RS08165	COG1064	alcohol dehydrogenase
CRH11_RS08180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRH11_RS08195	COG2814	Major facilitator Superfamily
CRH11_RS08200	COG1309	transcriptional regulator
CRH11_RS08205	COG0697	spore germination
CRH11_RS08210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRH11_RS08215	COG5577	PFAM Coat F domain
CRH11_RS08225	COG1063	alcohol dehydrogenase
CRH11_RS08230	COG5577	PFAM Coat F domain
CRH11_RS08245	COG4585	Histidine kinase
CRH11_RS08250	COG2197	response regulator
CRH11_RS08255	COG2409	Drug exporters of the RND superfamily
CRH11_RS08260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CRH11_RS08265	COG0488	(ABC) transporter
CRH11_RS08270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRH11_RS08275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRH11_RS08285	COG2814	Major facilitator Superfamily
CRH11_RS08290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRH11_RS08300	COG0730	response to heat
CRH11_RS08305	COG0456	acetyltransferase
CRH11_RS08310	COG0789	Transcriptional regulator
CRH11_RS08310	COG4978	Transcriptional regulator
CRH11_RS08315	COG0697	spore germination
CRH11_RS08320	COG1051	belongs to the nudix hydrolase family
CRH11_RS08325	COG2226	methyltransferase
CRH11_RS08335	COG1802	Transcriptional regulator
CRH11_RS08340	COG1819	glycosyl
CRH11_RS08355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CRH11_RS08360	COG1388	LysM domain
CRH11_RS08365	COG2814	Major facilitator Superfamily
CRH11_RS08370	COG2188	Transcriptional regulator
CRH11_RS08375	COG2186	Transcriptional regulator
CRH11_RS08380	COG2807	transmembrane transport
CRH11_RS08385	COG2076	Multidrug Resistance protein
CRH11_RS08390	COG2076	Multidrug Resistance protein
CRH11_RS08395	COG1309	transcriptional regulator
CRH11_RS08400	COG0531	amino acid
CRH11_RS08410	COG3832	glyoxalase III activity
CRH11_RS08415	COG0604	alcohol dehydrogenase
CRH11_RS08420	COG2814	Major facilitator Superfamily
CRH11_RS08460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CRH11_RS08465	COG0802	atpase or kinase
CRH11_RS08470	COG1214	PFAM Peptidase M22, glycoprotease
CRH11_RS08475	COG0456	acetyltransferase
CRH11_RS08480	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CRH11_RS08485	COG0488	(ABC) transporter
CRH11_RS08500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CRH11_RS08505	COG0805	protein transport
CRH11_RS08515	COG1266	CAAX protease self-immunity
CRH11_RS08540	COG0457	Tetratricopeptide repeat
CRH11_RS08545	COG1063	alcohol dehydrogenase
CRH11_RS08550	COG2211	Major facilitator Superfamily
CRH11_RS08555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRH11_RS08565	COG1842	Phage shock protein A
CRH11_RS08570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CRH11_RS08575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CRH11_RS08580	COG4260	virion core protein, lumpy skin disease virus
CRH11_RS08585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CRH11_RS08585	COG2755	lipolytic protein G-D-S-L family
CRH11_RS08595	COG1595	DNA-templated transcription, initiation
CRH11_RS08600	COG1063	alcohol dehydrogenase
CRH11_RS08605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CRH11_RS08610	COG0823	Involved in the tonB-independent uptake of proteins
CRH11_RS08620	COG2132	Multicopper oxidase
CRH11_RS08625	COG1113	amino acid transport
CRH11_RS08630	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CRH11_RS08635	COG0714	Associated with various cellular activities
CRH11_RS08640	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CRH11_RS08645	COG1305	Transglutaminase-like
CRH11_RS08665	COG2252	PERMEase
CRH11_RS08670	COG3064	Membrane
CRH11_RS08690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CRH11_RS08695	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CRH11_RS08700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CRH11_RS08705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CRH11_RS08710	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CRH11_RS08725	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CRH11_RS08735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CRH11_RS08740	COG0138	bifunctional purine biosynthesis protein purh
CRH11_RS08745	COG0151	Belongs to the GarS family
CRH11_RS08755	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CRH11_RS08760	COG1470	cell adhesion involved in biofilm formation
CRH11_RS08765	COG4496	protein, YerC YecD
CRH11_RS08770	COG0069	glutamate synthase activity
CRH11_RS08785	COG0210	DNA helicase
CRH11_RS08795	COG4851	CamS sex pheromone cAM373 precursor
CRH11_RS08800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CRH11_RS08805	COG1285	pathogenesis
CRH11_RS08810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRH11_RS08830	COG1309	transcriptional regulator
CRH11_RS08835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRH11_RS08840	COG1597	lipid kinase activity
CRH11_RS08845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CRH11_RS08855	COG1131	(ABC) transporter
CRH11_RS08895	COG5444	nuclease activity
CRH11_RS08925	COG3546	catalase activity
CRH11_RS08930	COG0454	-acetyltransferase
CRH11_RS08940	COG2323	membrane
CRH11_RS08945	COG2329	Antibiotic biosynthesis monooxygenase
CRH11_RS08950	COG0346	lactoylglutathione lyase activity
CRH11_RS08960	COG1366	Belongs to the anti-sigma-factor antagonist family
CRH11_RS08965	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CRH11_RS08970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CRH11_RS08975	COG4208	sulfate ABC transporter
CRH11_RS08985	COG5583	Uncharacterized small protein (DUF2292)
CRH11_RS08990	COG0196	riboflavin kinase activity
CRH11_RS08995	COG0670	Belongs to the BI1 family
CRH11_RS09000	COG1846	Transcriptional regulator
CRH11_RS09005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CRH11_RS09015	COG2124	cytochrome p450
CRH11_RS09015	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CRH11_RS09030	COG1131	(ABC) transporter
CRH11_RS09075	COG4106	trans-aconitate 2-methyltransferase activity
CRH11_RS09080	COG1368	sulfuric ester hydrolase activity
CRH11_RS09085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CRH11_RS09090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRH11_RS09095	COG1442	glycosyl transferase family 8
CRH11_RS09100	COG1216	Glycosyl transferase, family 2
CRH11_RS09105	COG1442	glycosyl transferase family 8
CRH11_RS09110	COG2223	nitrite transmembrane transporter activity
CRH11_RS09115	COG0531	amino acid
CRH11_RS09120	COG1012	belongs to the aldehyde dehydrogenase family
CRH11_RS09125	COG0840	transmembrane signaling receptor activity
CRH11_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS09135	COG0463	Glycosyl transferase, family 2
CRH11_RS09135	COG0457	Tetratricopeptide repeat
CRH11_RS09140	COG0488	(ABC) transporter
CRH11_RS09145	COG0789	Transcriptional regulator
CRH11_RS09150	COG2814	Major facilitator Superfamily
CRH11_RS09155	COG0488	(ABC) transporter
CRH11_RS09160	COG0513	Belongs to the DEAD box helicase family
CRH11_RS09165	COG0456	acetyltransferase
CRH11_RS09170	COG2130	NADP-dependent
CRH11_RS09185	COG3866	Pectate lyase
CRH11_RS09190	COG0471	metal ion transport
CRH11_RS09210	COG2972	Histidine kinase
CRH11_RS09210	COG0745	RESPONSE REGULATOR receiver
CRH11_RS09215	COG3279	Response regulator of the LytR AlgR family
CRH11_RS09225	COG3764	Sortase (surface protein transpeptidase)
CRH11_RS09235	COG3290	protein histidine kinase activity
CRH11_RS09240	COG4565	transcriptional regulatory protein
CRH11_RS09245	COG3181	Tripartite tricarboxylate transporter family receptor
CRH11_RS09250	COG2851	Citrate transporter
CRH11_RS09255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRH11_RS09260	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CRH11_RS09270	COG2258	MOSC domain
CRH11_RS09290	COG0024	Methionine aminopeptidase
CRH11_RS09295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRH11_RS09295	COG1263	PTS System
CRH11_RS09305	COG1368	sulfuric ester hydrolase activity
CRH11_RS09315	COG0071	Belongs to the small heat shock protein (HSP20) family
CRH11_RS09330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRH11_RS09330	COG1263	PTS System
CRH11_RS09335	COG0366	Alpha amylase catalytic
CRH11_RS09340	COG2188	Transcriptional regulator
CRH11_RS09345	COG0778	Nitroreductase
CRH11_RS09360	COG0737	Belongs to the 5'-nucleotidase family
CRH11_RS09365	COG0693	protein deglycase activity
CRH11_RS09370	COG1609	Transcriptional regulator
CRH11_RS09385	COG2814	Major facilitator Superfamily
CRH11_RS09395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CRH11_RS09400	COG4980	gas vesicle protein
CRH11_RS09405	COG1295	ribonuclease BN
CRH11_RS09410	COG0477	Major facilitator Superfamily
CRH11_RS09415	COG0387	Pfam Sodium calcium exchanger
CRH11_RS09425	COG0668	transmembrane transport
CRH11_RS09430	COG0535	radical SAM domain protein
CRH11_RS09440	COG0726	polysaccharide deacetylase
CRH11_RS09445	COG2084	Dehydrogenase
CRH11_RS09455	COG0598	Magnesium transport protein CorA
CRH11_RS09460	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CRH11_RS09465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CRH11_RS09475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRH11_RS09480	COG4637	Psort location Cytoplasmic, score
CRH11_RS09485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CRH11_RS09490	COG0022	dehydrogenase e1 component
CRH11_RS09495	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRH11_RS09500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRH11_RS09505	COG3284	Transcriptional regulator
CRH11_RS09515	COG1486	melibiose metabolic process
CRH11_RS09520	COG1737	Transcriptional regulator
CRH11_RS09525	COG1263	PTS System
CRH11_RS09525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRH11_RS09530	COG5434	Belongs to the glycosyl hydrolase 28 family
CRH11_RS09535	COG1132	(ABC) transporter
CRH11_RS09540	COG1132	(ABC) transporter
CRH11_RS09545	COG2259	Doxx family
CRH11_RS09550	COG2514	catechol 2,3-dioxygenase activity
CRH11_RS09565	COG1695	Transcriptional regulator
CRH11_RS09570	COG2249	NAD(P)H dehydrogenase (quinone) activity
CRH11_RS09575	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CRH11_RS09580	COG3848	Pyruvate phosphate dikinase
CRH11_RS09580	COG0574	Belongs to the PEP-utilizing enzyme family
CRH11_RS09585	COG2732	(Barnase) inhibitor
CRH11_RS09590	COG2318	DinB family
CRH11_RS09595	COG2814	Major facilitator Superfamily
CRH11_RS09600	COG1846	Transcriptional regulator
CRH11_RS09605	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CRH11_RS09605	COG0392	lysyltransferase activity
CRH11_RS09610	COG0384	phenazine biosynthesis protein PhzF
CRH11_RS09615	COG0778	Nitroreductase
CRH11_RS09630	COG1090	epimerase
CRH11_RS09645	COG2814	Major facilitator Superfamily
CRH11_RS09655	COG3591	Belongs to the peptidase S1B family
CRH11_RS09670	COG3103	Sh3 type 3 domain protein
CRH11_RS09675	COG5658	integral membrane protein
CRH11_RS09680	COG0596	Alpha beta hydrolase
CRH11_RS09685	COG0463	Glycosyl transferase, family 2
CRH11_RS09690	COG4485	Bacterial membrane protein, YfhO
CRH11_RS09695	COG1988	membrane-bound metal-dependent
CRH11_RS09700	COG1194	a g-specific adenine glycosylase
CRH11_RS09710	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS09730	COG1132	(ABC) transporter
CRH11_RS09735	COG4129	membrane
CRH11_RS09750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CRH11_RS09755	COG0735	belongs to the Fur family
CRH11_RS09865	COG1757	Na H antiporter
CRH11_RS09870	COG3340	Belongs to the peptidase S51 family
CRH11_RS09880	COG0277	FAD linked oxidase domain protein
CRH11_RS09890	COG0747	negative chemotaxis
CRH11_RS09895	COG0601	transmembrane transport
CRH11_RS09900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRH11_RS09905	COG0444	Belongs to the ABC transporter superfamily
CRH11_RS09910	COG4608	Belongs to the ABC transporter superfamily
CRH11_RS09915	COG0753	catalase activity
CRH11_RS09925	COG1116	anion transmembrane transporter activity
CRH11_RS09930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CRH11_RS09935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CRH11_RS09955	COG1476	TRANSCRIPTIONal
CRH11_RS09965	COG3382	B3 4 domain protein
CRH11_RS09970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CRH11_RS09980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CRH11_RS09985	COG0789	Transcriptional regulator
CRH11_RS09990	COG1664	Polymer-forming cytoskeletal
CRH11_RS09995	COG1664	Polymer-forming cytoskeletal
CRH11_RS10005	COG2766	serine protein kinase
CRH11_RS10020	COG1846	Transcriptional regulator
CRH11_RS10025	COG1566	PFAM secretion protein HlyD family protein
CRH11_RS10030	COG2814	Major facilitator Superfamily
CRH11_RS10035	COG0655	NAD(P)H dehydrogenase (quinone) activity
CRH11_RS10050	COG1725	Transcriptional regulator
CRH11_RS10055	COG1131	(ABC) transporter
CRH11_RS10060	COG1131	(ABC) transporter
CRH11_RS10065	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CRH11_RS10070	COG1278	Cold shock
CRH11_RS10080	COG1464	Belongs to the NlpA lipoprotein family
CRH11_RS10085	COG3706	GGDEF domain
CRH11_RS10090	COG1823	symporter activity
CRH11_RS10110	COG5577	PFAM Coat F domain
CRH11_RS10115	COG0737	Belongs to the 5'-nucleotidase family
CRH11_RS10115	COG1525	nuclease
CRH11_RS10115	COG4085	toxin activity
CRH11_RS10120	COG3764	Sortase (surface protein transpeptidase)
CRH11_RS10125	COG0564	pseudouridine synthase activity
CRH11_RS10135	COG0517	IMP dehydrogenase activity
CRH11_RS10140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CRH11_RS10145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CRH11_RS10145	COG3153	acetyltransferase
CRH11_RS10150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CRH11_RS10155	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CRH11_RS10160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CRH11_RS10170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CRH11_RS10175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CRH11_RS10180	COG2203	Gaf domain
CRH11_RS10180	COG4585	Histidine kinase
CRH11_RS10185	COG2197	response regulator
CRH11_RS10190	COG0431	NADPH-dependent FMN reductase
CRH11_RS10205	COG0791	NLP P60 protein
CRH11_RS10205	COG1388	LysM domain
CRH11_RS10210	COG1959	2 iron, 2 sulfur cluster binding
CRH11_RS10220	COG0668	transmembrane transport
CRH11_RS10225	COG2719	SpoVR family
CRH11_RS10230	COG1785	Belongs to the alkaline phosphatase family
CRH11_RS10235	COG1388	LysM domain
CRH11_RS10235	COG0791	NLP P60 protein
CRH11_RS10240	COG0583	DNA-binding transcription factor activity
CRH11_RS10245	COG0372	Belongs to the citrate synthase family
CRH11_RS10250	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS10255	COG0531	amino acid
CRH11_RS10260	COG0733	neurotransmitter:sodium symporter activity
CRH11_RS10275	COG1595	DNA-templated transcription, initiation
CRH11_RS10280	COG0204	Acyl-transferase
CRH11_RS10285	COG1253	flavin adenine dinucleotide binding
CRH11_RS10290	COG0789	Transcriptional regulator
CRH11_RS10295	COG0436	Aminotransferase
CRH11_RS10300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRH11_RS10305	COG1253	flavin adenine dinucleotide binding
CRH11_RS10310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CRH11_RS10315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CRH11_RS10320	COG0584	glycerophosphoryl diester phosphodiesterase
CRH11_RS10330	COG0668	transmembrane transport
CRH11_RS10335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CRH11_RS10340	COG0726	polysaccharide deacetylase
CRH11_RS10345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRH11_RS10350	COG3226	Transcriptional regulator
CRH11_RS10360	COG0589	response to stress
CRH11_RS10365	COG1132	(ABC) transporter
CRH11_RS10370	COG1132	(ABC) transporter
CRH11_RS10375	COG0702	epimerase
CRH11_RS10400	COG0189	ligase activity
CRH11_RS10405	COG0189	ligase activity
CRH11_RS10420	COG4335	DNA alkylation repair
CRH11_RS10425	COG0561	phosphatase activity
CRH11_RS10430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CRH11_RS10440	COG0475	glutathione-regulated potassium exporter activity
CRH11_RS10445	COG0490	domain, Protein
CRH11_RS10455	COG1024	Enoyl-CoA hydratase
CRH11_RS10465	COG4152	abc transporter atp-binding protein
CRH11_RS10470	COG1668	transmembrane transport
CRH11_RS10475	COG0420	3'-5' exonuclease activity
CRH11_RS10480	COG4717	serine-type aminopeptidase activity
CRH11_RS10500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRH11_RS10540	COG4980	gas vesicle protein
CRH11_RS10555	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CRH11_RS10560	COG0537	adenosine 5'-monophosphoramidase activity
CRH11_RS10565	COG1131	(ABC) transporter
CRH11_RS10570	COG4473	ABC transporter
CRH11_RS10580	COG1473	amidohydrolase
CRH11_RS10585	COG3069	C4-dicarboxylate transmembrane transporter activity
CRH11_RS10590	COG2329	Antibiotic biosynthesis monooxygenase
CRH11_RS10595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRH11_RS10605	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CRH11_RS10610	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CRH11_RS10615	COG1309	transcriptional regulator
CRH11_RS10620	COG1511	domain protein
CRH11_RS10625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CRH11_RS10635	COG1363	Peptidase, m42
CRH11_RS10640	COG1301	dicarboxylic acid transport
CRH11_RS10650	COG1234	tRNA 3'-trailer cleavage
CRH11_RS10655	COG0095	Lipoate-protein ligase
CRH11_RS10660	COG0702	epimerase
CRH11_RS10665	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS10675	COG0501	Belongs to the peptidase M48B family
CRH11_RS10680	COG1404	Belongs to the peptidase S8 family
CRH11_RS10690	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CRH11_RS10695	COG0406	alpha-ribazole phosphatase activity
CRH11_RS10700	COG0183	Belongs to the thiolase family
CRH11_RS10705	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS10710	COG1268	BioY protein
CRH11_RS10715	COG0840	transmembrane signaling receptor activity
CRH11_RS10720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRH11_RS10720	COG0723	plastoquinol--plastocyanin reductase activity
CRH11_RS10725	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS10735	COG4903	ComK protein
CRH11_RS10745	COG5646	InterPro IPR014922
CRH11_RS10770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRH11_RS10785	COG0398	Pfam SNARE associated Golgi protein
CRH11_RS10790	COG0681	Belongs to the peptidase S26 family
CRH11_RS10795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CRH11_RS10800	COG1846	Transcriptional regulator
CRH11_RS10805	COG3180	Ammonia monooxygenase
CRH11_RS10810	COG2814	Major facilitator Superfamily
CRH11_RS10820	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CRH11_RS10825	COG2323	membrane
CRH11_RS10840	COG0420	3'-5' exonuclease activity
CRH11_RS10845	COG0419	ATPase involved in DNA repair
CRH11_RS10850	COG1403	HNH endonuclease
CRH11_RS10890	COG0179	Fumarylacetoacetate (FAA) hydrolase
CRH11_RS10910	COG0367	asparagine synthase
CRH11_RS10915	COG1562	ergosterol biosynthetic process
CRH11_RS10920	COG0534	Mate efflux family protein
CRH11_RS10925	COG2207	Transcriptional regulator
CRH11_RS10925	COG1917	Cupin 2, conserved barrel domain protein
CRH11_RS10930	COG2318	DinB family
CRH11_RS10935	COG1279	arginine transmembrane transporter activity
CRH11_RS10940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRH11_RS10945	COG1357	PFAM Pentapeptide repeats (8 copies)
CRH11_RS10950	COG2153	protein acetylation
CRH11_RS10955	COG0646	methionine synthase
CRH11_RS10955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CRH11_RS10965	COG2996	Protein conserved in bacteria
CRH11_RS10970	COG1744	ABC transporter substrate-binding protein PnrA-like
CRH11_RS10975	COG0840	transmembrane signaling receptor activity
CRH11_RS10990	COG1307	EDD domain protein, DegV family
CRH11_RS10995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRH11_RS11010	COG0561	phosphatase activity
CRH11_RS11015	COG1073	alpha beta
CRH11_RS11020	COG2151	metal-sulfur cluster biosynthetic enzyme
CRH11_RS11030	COG0277	FAD linked oxidase domain protein
CRH11_RS11045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CRH11_RS11055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CRH11_RS11060	COG0505	Belongs to the CarA family
CRH11_RS11065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CRH11_RS11070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CRH11_RS11090	COG2267	carboxylic ester hydrolase activity
CRH11_RS11100	COG1744	ABC transporter substrate-binding protein PnrA-like
CRH11_RS11115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CRH11_RS11120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRH11_RS11125	COG5504	Zn-dependent protease
CRH11_RS11130	COG0444	Belongs to the ABC transporter superfamily
CRH11_RS11135	COG4608	Belongs to the ABC transporter superfamily
CRH11_RS11145	COG0601	transmembrane transport
CRH11_RS11150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRH11_RS11160	COG0180	Tryptophanyl-tRNA synthetase
CRH11_RS11165	COG4166	transmembrane transport
CRH11_RS11170	COG0601	transmembrane transport
CRH11_RS11175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRH11_RS11180	COG0444	Belongs to the ABC transporter superfamily
CRH11_RS11185	COG4608	Belongs to the ABC transporter superfamily
CRH11_RS11195	COG0456	acetyltransferase
CRH11_RS11200	COG1393	Belongs to the ArsC family
CRH11_RS11205	COG0861	Integral membrane protein TerC family
CRH11_RS11210	COG4862	establishment of competence for transformation
CRH11_RS11215	COG4469	Competence protein
CRH11_RS11220	COG1164	Oligoendopeptidase f
CRH11_RS11230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CRH11_RS11235	COG2346	COG2346, Truncated hemoglobins
CRH11_RS11240	COG0741	lytic transglycosylase activity
CRH11_RS11245	COG4116	CYTH
CRH11_RS11255	COG2357	RelA SpoT domain protein
CRH11_RS11260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CRH11_RS11265	COG0564	pseudouridine synthase activity
CRH11_RS11280	COG0475	glutathione-regulated potassium exporter activity
CRH11_RS11280	COG0569	domain protein
CRH11_RS11285	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CRH11_RS11290	COG0352	thiamine-phosphate diphosphorylase activity
CRH11_RS11295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRH11_RS11300	COG2104	thiamine diphosphate biosynthetic process
CRH11_RS11310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CRH11_RS11315	COG0351	phosphomethylpyrimidine kinase
CRH11_RS11320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CRH11_RS11375	COG0210	DNA helicase
CRH11_RS11395	COG1131	(ABC) transporter
CRH11_RS11405	COG2153	protein acetylation
CRH11_RS11415	COG2382	esterase
CRH11_RS11420	COG0626	cystathionine gamma-synthase activity
CRH11_RS11425	COG0626	cystathionine gamma-synthase activity
CRH11_RS11440	COG5444	nuclease activity
CRH11_RS11495	COG2367	Beta-lactamase
CRH11_RS11500	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CRH11_RS11510	COG1846	Transcriptional regulator
CRH11_RS11520	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CRH11_RS11525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CRH11_RS11530	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CRH11_RS11535	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRH11_RS11535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRH11_RS11540	COG1447	Phosphotransferase system cellobiose-specific component IIA
CRH11_RS11575	COG1285	pathogenesis
CRH11_RS11590	COG2205	protein histidine kinase activity
CRH11_RS11600	COG3383	formate dehydrogenase (NAD+) activity
CRH11_RS11605	COG2427	Protein of unknown function (DUF1641)
CRH11_RS11610	COG2124	cytochrome p450
CRH11_RS11615	COG1819	glycosyl
CRH11_RS11625	COG1587	Uroporphyrinogen-III synthase
CRH11_RS11630	COG0390	transport system, permease component
CRH11_RS11635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CRH11_RS11640	COG0697	spore germination
CRH11_RS11645	COG4297	protein containing double-stranded beta helix domain
CRH11_RS11655	COG1252	NADH dehydrogenase
CRH11_RS11665	COG2211	Major facilitator Superfamily
CRH11_RS11670	COG1609	Transcriptional regulator
CRH11_RS11675	COG0246	Mannitol dehydrogenase
CRH11_RS11680	COG2721	sulfolactate sulfo-lyase activity
CRH11_RS11685	COG0730	response to heat
CRH11_RS11690	COG2318	DinB family
CRH11_RS11695	COG0457	Tetratricopeptide repeat
CRH11_RS11705	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS11705	COG1388	LysM domain
CRH11_RS11705	COG5632	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS11715	COG4195	phage-related replication protein
CRH11_RS11720	COG2856	Zn peptidase
CRH11_RS11725	COG1396	sequence-specific DNA binding
CRH11_RS11735	COG1522	sequence-specific DNA binding
CRH11_RS11740	COG1484	DNA-dependent DNA replication
CRH11_RS11760	COG1595	DNA-templated transcription, initiation
CRH11_RS11765	COG3728	DNA packaging
CRH11_RS11765	COG5484	DNA packaging
CRH11_RS11770	COG1783	phage Terminase large subunit
CRH11_RS11775	COG5518	Phage portal protein
CRH11_RS11780	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CRH11_RS11785	COG4653	Phage capsid family
CRH11_RS11835	COG5412	phage tail tape measure protein
CRH11_RS11835	COG5412	phage tail tape measure protein
CRH11_RS11835	COG5412	phage tail tape measure protein
CRH11_RS11835	COG3953	SLT domain
CRH11_RS11835	COG3953	SLT domain
CRH11_RS11835	COG3953	SLT domain
CRH11_RS11840	COG1652	LysM domain
CRH11_RS11845	COG4193	domain, Protein
CRH11_RS11855	COG3628	GPW Gp25 family protein
CRH11_RS11860	COG3299	homolog of phage Mu protein gp47
CRH11_RS11865	COG3778	Protein conserved in bacteria
CRH11_RS11905	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS11905	COG5632	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS11920	COG0306	phosphate transporter
CRH11_RS11925	COG1392	Phosphate transport regulator
CRH11_RS11930	COG0531	amino acid
CRH11_RS11935	COG0346	lactoylglutathione lyase activity
CRH11_RS11940	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CRH11_RS11945	COG0463	Glycosyl transferase, family 2
CRH11_RS11950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRH11_RS11955	COG0477	Major facilitator Superfamily
CRH11_RS11960	COG2362	D-Aminopeptidase
CRH11_RS11965	COG0601	transmembrane transport
CRH11_RS11970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRH11_RS11975	COG0444	Belongs to the ABC transporter superfamily
CRH11_RS11980	COG4166	transmembrane transport
CRH11_RS11985	COG1619	proteins homologs of microcin C7 resistance protein MccF
CRH11_RS11990	COG4948	Mandelate Racemase Muconate Lactonizing
CRH11_RS11995	COG0791	NLP P60 protein
CRH11_RS12000	COG4608	Belongs to the ABC transporter superfamily
CRH11_RS12005	COG2706	6-phosphogluconolactonase activity
CRH11_RS12010	COG1834	amidinotransferase
CRH11_RS12015	COG1607	acyl-coa hydrolase
CRH11_RS12020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRH11_RS12025	COG2076	Multidrug Resistance protein
CRH11_RS12030	COG2076	Multidrug Resistance protein
CRH11_RS12035	COG0788	formyltetrahydrofolate deformylase activity
CRH11_RS12040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CRH11_RS12050	COG1764	response to oxidative stress
CRH11_RS12055	COG1846	Transcriptional regulator
CRH11_RS12060	COG1764	response to oxidative stress
CRH11_RS12075	COG0463	Glycosyl transferase, family 2
CRH11_RS12075	COG0457	Tetratricopeptide repeat
CRH11_RS12085	COG2814	Major facilitator Superfamily
CRH11_RS12090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CRH11_RS12100	COG1404	Belongs to the peptidase S8 family
CRH11_RS12105	COG1366	Belongs to the anti-sigma-factor antagonist family
CRH11_RS12110	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CRH11_RS12115	COG1122	ATPase activity
CRH11_RS12120	COG4721	ABC-type cobalt transport system, permease component
CRH11_RS12125	COG3858	chitin binding
CRH11_RS12125	COG1388	LysM domain
CRH11_RS12140	COG2239	Acts as a magnesium transporter
CRH11_RS12145	COG0789	Transcriptional regulator
CRH11_RS12160	COG1846	Transcriptional regulator
CRH11_RS12165	COG0726	polysaccharide deacetylase
CRH11_RS12170	COG1793	dna ligase
CRH11_RS12170	COG3285	dna ligase
CRH11_RS12175	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CRH11_RS12180	COG0586	Pfam SNARE associated Golgi protein
CRH11_RS12185	COG0861	Integral membrane protein TerC family
CRH11_RS12190	COG1191	sigma factor activity
CRH11_RS12215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CRH11_RS12220	COG2323	membrane
CRH11_RS12230	COG3594	Acyltransferase
CRH11_RS12235	COG5002	protein histidine kinase activity
CRH11_RS12240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CRH11_RS12255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CRH11_RS12260	COG0436	Aminotransferase
CRH11_RS12290	COG3852	Histidine kinase
CRH11_RS12295	COG1846	Transcriptional regulator
CRH11_RS12300	COG1360	Flagellar Motor Protein
CRH11_RS12305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CRH11_RS12310	COG0542	response to heat
CRH11_RS12320	COG3949	Membrane
CRH11_RS12335	COG0720	synthase
CRH11_RS12340	COG0602	queuosine metabolic process
CRH11_RS12350	COG1733	regulation of RNA biosynthetic process
CRH11_RS12355	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS12365	COG1388	LysM domain
CRH11_RS12365	COG4641	Protein conserved in bacteria
CRH11_RS12370	COG1388	LysM domain
CRH11_RS12375	COG3858	chitin binding
CRH11_RS12390	COG4873	Protein conserved in bacteria
CRH11_RS12400	COG3773	Cell wall hydrolase
CRH11_RS12405	COG2244	polysaccharide biosynthetic process
CRH11_RS12410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRH11_RS12415	COG2217	Heavy metal translocating P-type atpase
CRH11_RS12420	COG0006	proline dipeptidase activity
CRH11_RS12425	COG1609	Transcriptional regulator
CRH11_RS12430	COG3711	transcriptional antiterminator
CRH11_RS12435	COG2190	(PTS) system
CRH11_RS12435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRH11_RS12435	COG1263	PTS System
CRH11_RS12440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRH11_RS12445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CRH11_RS12455	COG1533	DNA photolyase activity
CRH11_RS12460	COG0840	transmembrane signaling receptor activity
CRH11_RS12465	COG2084	Dehydrogenase
CRH11_RS12470	COG2340	Cysteine-rich secretory protein family
CRH11_RS12475	COG0768	penicillin binding
CRH11_RS12480	COG4191	Histidine kinase
CRH11_RS12485	COG0436	Aminotransferase
CRH11_RS12500	COG0784	Response regulator, receiver
CRH11_RS12500	COG0835	chemotaxis
CRH11_RS12510	COG2814	Major facilitator Superfamily
CRH11_RS12515	COG1376	ErfK ybiS ycfS ynhG family protein
CRH11_RS12520	COG1408	metallophosphoesterase
CRH11_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS12535	COG2200	EAL domain
CRH11_RS12540	COG4703	Protein of unknown function (DUF1797)
CRH11_RS12545	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CRH11_RS12555	COG0517	IMP dehydrogenase activity
CRH11_RS12560	COG0583	DNA-binding transcription factor activity
CRH11_RS12565	COG0716	FMN binding
CRH11_RS12575	COG0716	FMN binding
CRH11_RS12595	COG0668	transmembrane transport
CRH11_RS12600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRH11_RS12620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CRH11_RS12625	COG0303	'Molybdopterin
CRH11_RS12630	COG1763	Mo-molybdopterin cofactor biosynthetic process
CRH11_RS12635	COG0314	molybdopterin synthase activity
CRH11_RS12640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CRH11_RS12650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRH11_RS12655	COG1136	(ABC) transporter
CRH11_RS12660	COG0577	efflux transmembrane transporter activity
CRH11_RS12665	COG1349	DNA-binding transcription factor activity
CRH11_RS12670	COG1105	Belongs to the carbohydrate kinase PfkB family
CRH11_RS12675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRH11_RS12675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRH11_RS12675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRH11_RS12680	COG0681	Belongs to the peptidase S26 family
CRH11_RS12690	COG0488	(ABC) transporter
CRH11_RS12695	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CRH11_RS12700	COG2309	aminopeptidase activity
CRH11_RS12710	COG1077	Cell shape determining protein MreB Mrl
CRH11_RS12720	COG2002	toxin-antitoxin pair type II binding
CRH11_RS12725	COG3852	Histidine kinase
CRH11_RS12730	COG2105	PFAM AIG2 family protein
CRH11_RS12730	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CRH11_RS12735	COG0569	domain protein
CRH11_RS12745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CRH11_RS12755	COG0561	phosphatase activity
CRH11_RS12760	COG0242	peptide deformylase activity
CRH11_RS12770	COG0497	DNA recombination
CRH11_RS12785	COG4221	oxidoreductase activity
CRH11_RS12785	COG3321	synthase
CRH11_RS12785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS12785	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS12790	COG4221	oxidoreductase activity
CRH11_RS12790	COG0300	oxidoreductase activity
CRH11_RS12790	COG3321	synthase
CRH11_RS12790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS12795	COG3321	synthase
CRH11_RS12795	COG4221	oxidoreductase activity
CRH11_RS12795	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS12795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS12800	COG3321	synthase
CRH11_RS12800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS12800	COG0300	oxidoreductase activity
CRH11_RS12800	COG4221	oxidoreductase activity
CRH11_RS12805	COG4221	oxidoreductase activity
CRH11_RS12805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS12805	COG3321	synthase
CRH11_RS12805	COG0300	oxidoreductase activity
CRH11_RS12810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS12810	COG4221	oxidoreductase activity
CRH11_RS12810	COG0300	oxidoreductase activity
CRH11_RS12810	COG3321	synthase
CRH11_RS12815	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS12815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS12815	COG3321	synthase
CRH11_RS12815	COG4221	oxidoreductase activity
CRH11_RS12820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CRH11_RS12825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CRH11_RS12830	COG0022	dehydrogenase e1 component
CRH11_RS12835	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRH11_RS12840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRH11_RS12845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRH11_RS12860	COG1982	Orn Lys Arg decarboxylase major
CRH11_RS12885	COG0483	inositol monophosphate 1-phosphatase activity
CRH11_RS12895	COG3227	Zinc metalloprotease (Elastase)
CRH11_RS12900	COG1595	DNA-templated transcription, initiation
CRH11_RS12920	COG1217	gtp-binding protein TYPA
CRH11_RS12930	COG4896	Protein conserved in bacteria
CRH11_RS12940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CRH11_RS12945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CRH11_RS12950	COG2066	Belongs to the glutaminase family
CRH11_RS12960	COG0772	Belongs to the SEDS family
CRH11_RS12965	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CRH11_RS12980	COG2010	Cytochrome c
CRH11_RS12980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CRH11_RS12985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CRH11_RS12990	COG1845	cytochrome c oxidase, subunit III
CRH11_RS12995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CRH11_RS13000	COG3336	cytochrome c oxidase
CRH11_RS13010	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CRH11_RS13015	COG2340	Cysteine-rich secretory protein family
CRH11_RS13030	COG3679	Belongs to the UPF0342 family
CRH11_RS13040	COG0742	ribosomal rna small subunit methyltransferase
CRH11_RS13050	COG3314	Sporulation integral membrane protein YlbJ
CRH11_RS13055	COG1752	Esterase of the alpha-beta hydrolase superfamily
CRH11_RS13060	COG3480	Lon protease (S16) C-terminal proteolytic domain
CRH11_RS13070	COG1399	metal-binding, possibly nucleic acid-binding protein
CRH11_RS13090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CRH11_RS13110	COG4839	cell division protein FtsL
CRH11_RS13115	COG0768	penicillin binding
CRH11_RS13120	COG0768	penicillin binding
CRH11_RS13140	COG0772	Belongs to the SEDS family
CRH11_RS13155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CRH11_RS13160	COG0849	cell division
CRH11_RS13165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CRH11_RS13170	COG1404	Belongs to the peptidase S8 family
CRH11_RS13170	COG4412	M6 family metalloprotease domain protein
CRH11_RS13180	COG1191	sigma factor activity
CRH11_RS13185	COG1191	sigma factor activity
CRH11_RS13190	COG1119	ATPase activity
CRH11_RS13195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRH11_RS13200	COG1873	PFAM PRC-barrel domain
CRH11_RS13205	COG1496	oxidoreductase activity
CRH11_RS13210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CRH11_RS13220	COG0762	integral membrane protein
CRH11_RS13225	COG2302	S4 RNA-binding domain
CRH11_RS13230	COG3599	regulation of cell shape
CRH11_RS13240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CRH11_RS13245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CRH11_RS13255	COG0564	pseudouridine synthase activity
CRH11_RS13265	COG2233	PERMEase
CRH11_RS13275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CRH11_RS13280	COG0505	Belongs to the CarA family
CRH11_RS13285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CRH11_RS13300	COG0284	orotidine-5'-phosphate decarboxylase activity
CRH11_RS13305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CRH11_RS13315	COG0306	phosphate transporter
CRH11_RS13330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CRH11_RS13335	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CRH11_RS13340	COG1648	precorrin-2 dehydrogenase activity
CRH11_RS13360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CRH11_RS13365	COG1561	YicC-like family, N-terminal region
CRH11_RS13375	COG0194	GDP metabolic process
CRH11_RS13385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CRH11_RS13390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CRH11_RS13395	COG0242	peptide deformylase activity
CRH11_RS13405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CRH11_RS13405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CRH11_RS13415	COG0631	protein serine/threonine phosphatase activity
CRH11_RS13420	COG0515	serine threonine protein kinase
CRH11_RS13420	COG2815	serine threonine protein kinase
CRH11_RS13430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CRH11_RS13435	COG1564	THIamine pyrophosphokinase
CRH11_RS13450	COG1302	Protein conserved in bacteria
CRH11_RS13455	COG1461	Dihydroxyacetone kinase
CRH11_RS13460	COG1760	l-serine dehydratase
CRH11_RS13465	COG1760	l-serine dehydratase
CRH11_RS13470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CRH11_RS13485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CRH11_RS13490	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS13505	COG1196	nuclear chromosome segregation
CRH11_RS13510	COG0552	protein localization to endoplasmic reticulum
CRH11_RS13525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CRH11_RS13535	COG1837	Belongs to the UPF0109 family
CRH11_RS13560	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CRH11_RS13575	COG2257	FlhB HrpN YscU SpaS Family
CRH11_RS13585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CRH11_RS13590	COG0758	DNA mediated transformation
CRH11_RS13595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CRH11_RS13605	COG4974	Belongs to the 'phage' integrase family
CRH11_RS13625	COG1815	bacterial-type flagellum-dependent cell motility
CRH11_RS13630	COG1558	bacterial-type flagellum-dependent cell motility
CRH11_RS13635	COG1677	Flagellar hook-basal body complex protein FliE
CRH11_RS13640	COG1766	The M ring may be actively involved in energy transduction
CRH11_RS13645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CRH11_RS13650	COG1317	bacterial-type flagellum organization
CRH11_RS13655	COG1157	protein secretion by the type III secretion system
CRH11_RS13660	COG2882	bacterial-type flagellum organization
CRH11_RS13665	COG3334	PFAM MgtE intracellular
CRH11_RS13670	COG3144	bacterial-type flagellum assembly
CRH11_RS13675	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CRH11_RS13680	COG4786	Flagellar basal body rod
CRH11_RS13685	COG1582	Flagellar protein (FlbD)
CRH11_RS13690	COG1580	Controls the rotational direction of flagella during chemotaxis
CRH11_RS13695	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CRH11_RS13700	COG1776	CheC inhibitor of MCP methylation
CRH11_RS13700	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CRH11_RS13705	COG2201	protein-glutamate methylesterase activity
CRH11_RS13710	COG3190	flagellar
CRH11_RS13715	COG1338	Plays a role in the flagellum-specific transport system
CRH11_RS13720	COG1987	bacterial-type flagellum assembly
CRH11_RS13725	COG1684	flagellar biosynthetic protein fliR
CRH11_RS13730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CRH11_RS13735	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CRH11_RS13740	COG1419	protein localization to endoplasmic reticulum
CRH11_RS13745	COG0455	bacterial-type flagellum organization
CRH11_RS13750	COG2201	protein-glutamate methylesterase activity
CRH11_RS13755	COG0643	Histidine kinase
CRH11_RS13755	COG2198	Histidine kinase
CRH11_RS13760	COG0835	chemotaxis
CRH11_RS13765	COG1776	CheC inhibitor of MCP methylation
CRH11_RS13775	COG1191	sigma factor activity
CRH11_RS13805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CRH11_RS13810	COG4589	Belongs to the CDS family
CRH11_RS13820	COG0750	zinc metalloprotease
CRH11_RS13830	COG2176	DNA-directed DNA polymerase activity
CRH11_RS13840	COG0195	Participates in both transcription termination and antitermination
CRH11_RS13845	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CRH11_RS13850	COG1358	cellular component organization or biogenesis
CRH11_RS13860	COG1550	Protein conserved in bacteria
CRH11_RS13875	COG0196	riboflavin kinase activity
CRH11_RS13890	COG0726	polysaccharide deacetylase
CRH11_RS13895	COG0612	Peptidase, M16
CRH11_RS13900	COG1873	PFAM PRC-barrel domain
CRH11_RS13905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRH11_RS13910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CRH11_RS13915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CRH11_RS13920	COG0527	aspartate kinase activity
CRH11_RS13930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CRH11_RS13935	COG0740	serine-type endopeptidase activity
CRH11_RS13945	COG1674	ftsk spoiiie
CRH11_RS13945	COG4980	gas vesicle protein
CRH11_RS13950	COG2188	Transcriptional regulator
CRH11_RS13955	COG2814	Major facilitator Superfamily
CRH11_RS13960	COG1846	Transcriptional regulator
CRH11_RS13965	COG2409	Drug exporters of the RND superfamily
CRH11_RS13965	COG1033	growth of symbiont in host cell
CRH11_RS13970	COG0612	Peptidase, M16
CRH11_RS13975	COG0612	Peptidase, M16
CRH11_RS13980	COG0300	oxidoreductase activity
CRH11_RS13995	COG1426	Protein conserved in bacteria
CRH11_RS14000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CRH11_RS14015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CRH11_RS14025	COG1692	metallophosphoesterase
CRH11_RS14030	COG2359	stage V sporulation protein S
CRH11_RS14050	COG4550	Control of competence regulator ComK, YlbF/YmcA
CRH11_RS14100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS14105	COG3425	synthase
CRH11_RS14110	COG1024	Enoyl-CoA hydratase
CRH11_RS14115	COG1024	Enoyl-CoA hydratase
CRH11_RS14120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS14120	COG0300	oxidoreductase activity
CRH11_RS14120	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS14120	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS14120	COG3321	synthase
CRH11_RS14125	COG4221	oxidoreductase activity
CRH11_RS14125	COG3321	synthase
CRH11_RS14125	COG0300	oxidoreductase activity
CRH11_RS14125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS14130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS14130	COG3321	synthase
CRH11_RS14130	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS14130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS14130	COG3321	synthase
CRH11_RS14130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS14130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS14130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRH11_RS14130	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS14130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRH11_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS14135	COG3321	synthase
CRH11_RS14135	COG4221	oxidoreductase activity
CRH11_RS14135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS14140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CRH11_RS14140	COG3321	synthase
CRH11_RS14140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS14140	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CRH11_RS14145	COG2124	cytochrome p450
CRH11_RS14150	COG3209	COG3209 Rhs family protein
CRH11_RS14155	COG3619	membrane
CRH11_RS14165	COG1404	Belongs to the peptidase S8 family
CRH11_RS14175	COG4195	phage-related replication protein
CRH11_RS14180	COG1764	response to oxidative stress
CRH11_RS14190	COG2076	Multidrug Resistance protein
CRH11_RS14230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRH11_RS14235	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRH11_RS14240	COG4112	unkown
CRH11_RS14245	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS14255	COG0464	growth
CRH11_RS14260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CRH11_RS14265	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CRH11_RS14270	COG0789	Transcriptional regulator
CRH11_RS14275	COG0174	glutamine synthetase
CRH11_RS14285	COG2211	Major facilitator Superfamily
CRH11_RS14290	COG3507	Belongs to the glycosyl hydrolase 43 family
CRH11_RS14305	COG1070	Carbohydrate kinase
CRH11_RS14310	COG0574	Belongs to the PEP-utilizing enzyme family
CRH11_RS14310	COG3848	Pyruvate phosphate dikinase
CRH11_RS14340	COG1064	alcohol dehydrogenase
CRH11_RS14370	COG0456	acetyltransferase
CRH11_RS14405	COG3397	chitin binding
CRH11_RS14425	COG5434	Belongs to the glycosyl hydrolase 28 family
CRH11_RS14430	COG0756	dUTP diphosphatase activity
CRH11_RS14440	COG4195	phage-related replication protein
CRH11_RS14470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CRH11_RS14480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CRH11_RS14500	COG0785	Cytochrome C biogenesis protein
CRH11_RS14505	COG2201	protein-glutamate methylesterase activity
CRH11_RS14510	COG4846	Membrane protein involved in cytochrome C biogenesis
CRH11_RS14520	COG0071	Belongs to the small heat shock protein (HSP20) family
CRH11_RS14535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CRH11_RS14540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRH11_RS14560	COG0824	Thioesterase
CRH11_RS14570	COG4841	protein insertion into membrane
CRH11_RS14580	COG1832	CoA-binding protein
CRH11_RS14585	COG0187	DNA topoisomerase II activity
CRH11_RS14590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CRH11_RS14600	COG1115	amino acid carrier protein
CRH11_RS14610	COG1063	alcohol dehydrogenase
CRH11_RS14615	COG0800	Aldolase
CRH11_RS14620	COG1312	Catalyzes the dehydration of D-mannonate
CRH11_RS14625	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS14630	COG1609	Transcriptional regulator
CRH11_RS14635	COG2271	Major facilitator Superfamily
CRH11_RS14660	COG0577	efflux transmembrane transporter activity
CRH11_RS14660	COG1136	(ABC) transporter
CRH11_RS14690	COG2205	protein histidine kinase activity
CRH11_RS14695	COG0745	RESPONSE REGULATOR receiver
CRH11_RS14705	COG3507	Belongs to the glycosyl hydrolase 43 family
CRH11_RS14730	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS14735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CRH11_RS14740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CRH11_RS14745	COG2610	gluconate transmembrane transporter activity
CRH11_RS14750	COG2124	cytochrome p450
CRH11_RS14770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CRH11_RS14780	COG2246	polysaccharide biosynthetic process
CRH11_RS14785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CRH11_RS14790	COG0586	Pfam SNARE associated Golgi protein
CRH11_RS14795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CRH11_RS14800	COG1024	Enoyl-CoA hydratase
CRH11_RS14805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CRH11_RS14810	COG0511	ligase activity, forming carbon-carbon bonds
CRH11_RS14815	COG0439	Biotin carboxylase
CRH11_RS14820	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS14825	COG1960	acyl-CoA dehydrogenase activity
CRH11_RS14830	COG1649	PFAM Uncharacterised BCR, COG1649
CRH11_RS14840	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CRH11_RS14840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS14845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS14850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS14855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS14860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS14870	COG2027	D-alanyl-D-alanine carboxypeptidase
CRH11_RS14875	COG2017	converts alpha-aldose to the beta-anomer
CRH11_RS14880	COG0534	Mate efflux family protein
CRH11_RS14890	COG5444	nuclease activity
CRH11_RS14905	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS14905	COG5632	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS14910	COG4824	toxin secretion phage lysis holin
CRH11_RS14930	COG5434	Belongs to the glycosyl hydrolase 28 family
CRH11_RS14935	COG1388	LysM domain
CRH11_RS14935	COG1705	Flagellar rod assembly protein muramidase FlgJ
CRH11_RS15010	COG4626	Terminase
CRH11_RS15010	COG1802	Transcriptional regulator
CRH11_RS15040	COG0582	viral genome integration into host DNA
CRH11_RS15045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CRH11_RS15135	COG4974	Belongs to the 'phage' integrase family
CRH11_RS15145	COG0582	viral genome integration into host DNA
CRH11_RS15150	COG0166	Belongs to the GPI family
CRH11_RS15155	COG0405	Gamma-glutamyltransferase
CRH11_RS15160	COG2814	Major facilitator Superfamily
CRH11_RS15165	COG0640	Transcriptional regulator
CRH11_RS15170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CRH11_RS15190	COG0493	'glutamate synthase
CRH11_RS15195	COG0070	glutamate synthase
CRH11_RS15195	COG0069	glutamate synthase activity
CRH11_RS15195	COG0067	glutamate synthase
CRH11_RS15200	COG0583	DNA-binding transcription factor activity
CRH11_RS15205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CRH11_RS15220	COG0300	oxidoreductase activity
CRH11_RS15225	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CRH11_RS15235	COG2814	Major facilitator Superfamily
CRH11_RS15240	COG1070	Carbohydrate kinase
CRH11_RS15245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CRH11_RS15280	COG5444	nuclease activity
CRH11_RS15285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRH11_RS15290	COG2207	Transcriptional regulator
CRH11_RS15290	COG0662	Cupin 2, conserved barrel domain protein
CRH11_RS15295	COG1309	transcriptional regulator
CRH11_RS15300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRH11_RS15310	COG0640	Transcriptional regulator
CRH11_RS15315	COG0741	lytic transglycosylase activity
CRH11_RS15320	COG2322	membrane
CRH11_RS15335	COG1619	proteins homologs of microcin C7 resistance protein MccF
CRH11_RS15345	COG1388	LysM domain
CRH11_RS15345	COG3584	3D domain protein
CRH11_RS15350	COG0514	ATP-dependent DNA helicase (RecQ)
CRH11_RS15360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CRH11_RS15365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CRH11_RS15380	COG0071	Belongs to the small heat shock protein (HSP20) family
CRH11_RS15410	COG1012	belongs to the aldehyde dehydrogenase family
CRH11_RS15415	COG1657	PFAM Prenyltransferase squalene oxidase
CRH11_RS15420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CRH11_RS15425	COG0733	neurotransmitter:sodium symporter activity
CRH11_RS15430	COG0385	Bile acid
CRH11_RS15435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRH11_RS15440	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRH11_RS15450	COG4548	von Willebrand factor, type A
CRH11_RS15455	COG0714	Associated with various cellular activities
CRH11_RS15460	COG2032	superoxide dismutase activity
CRH11_RS15465	COG0791	NLP P60 protein
CRH11_RS15465	COG1388	LysM domain
CRH11_RS15470	COG1819	glycosyl
CRH11_RS15475	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CRH11_RS15480	COG0534	Mate efflux family protein
CRH11_RS15485	COG1366	Belongs to the anti-sigma-factor antagonist family
CRH11_RS15490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CRH11_RS15495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CRH11_RS15505	COG2962	Rard protein
CRH11_RS15520	COG1942	4-Oxalocrotonate Tautomerase
CRH11_RS15530	COG1733	regulation of RNA biosynthetic process
CRH11_RS15535	COG0778	Nitroreductase
CRH11_RS15540	COG0400	carboxylic ester hydrolase activity
CRH11_RS15545	COG0346	lactoylglutathione lyase activity
CRH11_RS15555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRH11_RS15565	COG2723	6-phospho-beta-galactosidase activity
CRH11_RS15570	COG2188	Transcriptional regulator
CRH11_RS15575	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS15575	COG0793	Belongs to the peptidase S41A family
CRH11_RS15580	COG2226	methyltransferase
CRH11_RS15590	COG1876	peptidase activity
CRH11_RS15610	COG0671	phosphoesterase, PA-phosphatase related
CRH11_RS15645	COG1509	lysine 2,3-aminomutase activity
CRH11_RS15650	COG0456	acetyltransferase
CRH11_RS15655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRH11_RS15660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CRH11_RS15665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CRH11_RS15670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CRH11_RS15675	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CRH11_RS15685	COG0456	acetyltransferase
CRH11_RS15690	COG0463	Glycosyl transferase, family 2
CRH11_RS15705	COG4641	Protein conserved in bacteria
CRH11_RS15715	COG1086	Polysaccharide biosynthesis protein
CRH11_RS15725	COG3331	DNA recombination
CRH11_RS15745	COG1388	LysM domain
CRH11_RS15750	COG0457	Tetratricopeptide repeat
CRH11_RS15780	COG5444	nuclease activity
CRH11_RS15785	COG4282	regulation of fungal-type cell wall biogenesis
CRH11_RS15790	COG1525	nuclease
CRH11_RS15795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CRH11_RS15815	COG1846	Transcriptional regulator
CRH11_RS15820	COG4698	Protein conserved in bacteria
CRH11_RS15825	COG2755	lipolytic protein G-D-S-L family
CRH11_RS15830	COG1999	signal sequence binding
CRH11_RS15840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CRH11_RS15845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CRH11_RS15850	COG1272	protein, Hemolysin III
CRH11_RS15855	COG0204	Acyl-transferase
CRH11_RS15860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CRH11_RS15875	COG2521	methyltransferase
CRH11_RS15875	COG2136	Putative SAM-dependent methyltransferase
CRH11_RS15890	COG1413	lyase activity
CRH11_RS15895	COG1418	mRNA catabolic process
CRH11_RS15900	COG0386	Belongs to the glutathione peroxidase family
CRH11_RS15910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CRH11_RS15915	COG1278	Cold shock
CRH11_RS15935	COG0328	RNA-DNA hybrid ribonuclease activity
CRH11_RS15940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CRH11_RS15945	COG0328	RNA-DNA hybrid ribonuclease activity
CRH11_RS15955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRH11_RS15970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CRH11_RS15980	COG1755	Isoprenylcysteine carboxyl methyltransferase
CRH11_RS15985	COG3424	synthase
CRH11_RS16010	COG1335	isochorismatase
CRH11_RS16020	COG2233	PERMEase
CRH11_RS16030	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CRH11_RS16035	COG1199	ATP-dependent helicase activity
CRH11_RS16050	COG0116	Belongs to the methyltransferase superfamily
CRH11_RS16075	COG3359	exonuclease
CRH11_RS16080	COG1205	dead DEAH box helicase
CRH11_RS16080	COG1111	helicase
CRH11_RS16085	COG2190	(PTS) system
CRH11_RS16090	COG0071	Belongs to the small heat shock protein (HSP20) family
CRH11_RS16130	COG4499	WXG100 protein secretion system (Wss), protein YukC
CRH11_RS16130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRH11_RS16140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CRH11_RS16145	COG3935	DnaD domain protein
CRH11_RS16155	COG0436	Aminotransferase
CRH11_RS16160	COG5353	protein conserved in bacteria
CRH11_RS16170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRH11_RS16170	COG1199	ATP-dependent helicase activity
CRH11_RS16200	COG0438	transferase activity, transferring glycosyl groups
CRH11_RS16205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CRH11_RS16220	COG1694	Mazg nucleotide pyrophosphohydrolase
CRH11_RS16225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRH11_RS16230	COG2140	Oxalate decarboxylase
CRH11_RS16240	COG4347	Protein of unknown function (DUF1405)
CRH11_RS16245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CRH11_RS16245	COG2010	Cytochrome c
CRH11_RS16250	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CRH11_RS16255	COG0723	plastoquinol--plastocyanin reductase activity
CRH11_RS16270	COG0457	Tetratricopeptide repeat
CRH11_RS16285	COG0287	Prephenate dehydrogenase
CRH11_RS16320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CRH11_RS16325	COG4401	Chorismate mutase type I
CRH11_RS16340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CRH11_RS16345	COG0105	UTP biosynthetic process
CRH11_RS16350	COG0142	geranyltranstransferase activity
CRH11_RS16360	COG0142	geranyltranstransferase activity
CRH11_RS16375	COG0776	regulation of translation
CRH11_RS16380	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CRH11_RS16420	COG0539	negative regulation of cytoplasmic translation
CRH11_RS16435	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CRH11_RS16440	COG2959	enzyme of heme biosynthesis
CRH11_RS16445	COG3773	Cell wall hydrolase
CRH11_RS16445	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS16450	COG2339	peptidase activity
CRH11_RS16455	COG0492	ferredoxin-NADP+ reductase activity
CRH11_RS16460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CRH11_RS16465	COG4862	establishment of competence for transformation
CRH11_RS16470	COG1408	metallophosphoesterase
CRH11_RS16480	COG1388	LysM domain
CRH11_RS16485	COG1266	CAAX protease self-immunity
CRH11_RS16490	COG0514	ATP-dependent DNA helicase (RecQ)
CRH11_RS16495	COG4955	Helix-turn-helix domain
CRH11_RS16500	COG1141	Ferredoxin
CRH11_RS16505	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CRH11_RS16510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CRH11_RS16520	COG1595	DNA-templated transcription, initiation
CRH11_RS16525	COG5002	protein histidine kinase activity
CRH11_RS16530	COG0745	RESPONSE REGULATOR receiver
CRH11_RS16535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CRH11_RS16540	COG1333	cytochrome c biogenesis protein
CRH11_RS16545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRH11_RS16550	COG1187	pseudouridine synthase activity
CRH11_RS16555	COG0700	Nucleoside recognition
CRH11_RS16560	COG2715	membrane protein required for spore maturation
CRH11_RS16565	COG1686	Belongs to the peptidase S11 family
CRH11_RS16590	COG1547	Domain of unknown function (DUF309)
CRH11_RS16600	COG0456	acetyltransferase
CRH11_RS16615	COG0307	riboflavin synthase, alpha
CRH11_RS16620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CRH11_RS16620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CRH11_RS16630	COG0681	Belongs to the peptidase S26 family
CRH11_RS16640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CRH11_RS16645	COG4086	secreted protein
CRH11_RS16650	COG0019	diaminopimelate decarboxylase activity
CRH11_RS16655	COG0697	spore germination
CRH11_RS16670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CRH11_RS16690	COG1191	sigma factor activity
CRH11_RS16700	COG1366	Belongs to the anti-sigma-factor antagonist family
CRH11_RS16705	COG1686	Belongs to the peptidase S11 family
CRH11_RS16710	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CRH11_RS16715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CRH11_RS16720	COG4974	Belongs to the 'phage' integrase family
CRH11_RS16730	COG0735	belongs to the Fur family
CRH11_RS16735	COG1300	Membrane
CRH11_RS16750	COG0281	malic enzyme
CRH11_RS16755	COG1757	Na H antiporter
CRH11_RS16760	COG1027	Aspartate ammonia-lyase
CRH11_RS16765	COG0252	asparaginase activity
CRH11_RS16770	COG1396	sequence-specific DNA binding
CRH11_RS16775	COG1379	DNA repair
CRH11_RS16780	COG0494	nUDIX hydrolase
CRH11_RS16790	COG0667	Aldo Keto reductase
CRH11_RS16800	COG1073	alpha beta
CRH11_RS16810	COG4918	Iron-sulphur cluster biosynthesis
CRH11_RS16815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CRH11_RS16815	COG0456	acetyltransferase
CRH11_RS16820	COG2329	Antibiotic biosynthesis monooxygenase
CRH11_RS16825	COG0456	acetyltransferase
CRH11_RS16830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CRH11_RS16845	COG0628	permease
CRH11_RS16855	COG0346	lactoylglutathione lyase activity
CRH11_RS16865	COG3048	D-serine ammonia-lyase activity
CRH11_RS16870	COG0300	oxidoreductase activity
CRH11_RS16875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRH11_RS16880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CRH11_RS16885	COG1024	Enoyl-CoA hydratase
CRH11_RS16890	COG3425	synthase
CRH11_RS16895	COG2124	cytochrome p450
CRH11_RS16900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRH11_RS16900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS16900	COG3321	synthase
CRH11_RS16900	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS16900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS16905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS16905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRH11_RS16905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS16905	COG3321	synthase
CRH11_RS16905	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS16910	COG3321	synthase
CRH11_RS16910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS16910	COG0300	oxidoreductase activity
CRH11_RS16910	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS16915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS16915	COG3321	synthase
CRH11_RS16915	COG0300	oxidoreductase activity
CRH11_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS16915	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS16920	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS16920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS16920	COG3321	synthase
CRH11_RS16920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRH11_RS16920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS16925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS16925	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS16925	COG3321	synthase
CRH11_RS16925	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS16925	COG0300	oxidoreductase activity
CRH11_RS16930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRH11_RS16930	COG3321	synthase
CRH11_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS16930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRH11_RS16930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRH11_RS16935	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS16940	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS16955	COG2070	2-Nitropropane dioxygenase
CRH11_RS16955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CRH11_RS16965	COG0250	Participates in transcription elongation, termination and antitermination
CRH11_RS16990	COG0596	Alpha beta hydrolase
CRH11_RS17005	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CRH11_RS17010	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CRH11_RS17025	COG0706	membrane insertase activity
CRH11_RS17030	COG2195	Cleaves the N-terminal amino acid of tripeptides
CRH11_RS17035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CRH11_RS17040	COG0346	lactoylglutathione lyase activity
CRH11_RS17045	COG1376	ErfK ybiS ycfS ynhG family protein
CRH11_RS17050	COG4129	membrane
CRH11_RS17055	COG1126	abc transporter atp-binding protein
CRH11_RS17060	COG0765	amino acid transport
CRH11_RS17065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRH11_RS17075	COG1597	lipid kinase activity
CRH11_RS17080	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRH11_RS17085	COG0022	dehydrogenase e1 component
CRH11_RS17090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CRH11_RS17095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRH11_RS17100	COG3426	butyrate kinase activity
CRH11_RS17105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CRH11_RS17110	COG0280	phosphate acetyltransferase
CRH11_RS17115	COG3829	transcription factor binding
CRH11_RS17115	COG3290	protein histidine kinase activity
CRH11_RS17125	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CRH11_RS17130	COG2079	MmgE PrpD family protein
CRH11_RS17135	COG0372	Belongs to the citrate synthase family
CRH11_RS17140	COG1960	acyl-CoA dehydrogenase activity
CRH11_RS17145	COG1250	3-hydroxyacyl-CoA dehydrogenase
CRH11_RS17150	COG0183	Belongs to the thiolase family
CRH11_RS17155	COG0584	glycerophosphoryl diester phosphodiesterase
CRH11_RS17160	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS17180	COG1902	pentaerythritol trinitrate reductase activity
CRH11_RS17195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CRH11_RS17200	COG0745	RESPONSE REGULATOR receiver
CRH11_RS17205	COG0750	zinc metalloprotease
CRH11_RS17210	COG0497	DNA recombination
CRH11_RS17220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CRH11_RS17230	COG0142	geranyltranstransferase activity
CRH11_RS17240	COG1570	exodeoxyribonuclease VII activity
CRH11_RS17255	COG1302	Protein conserved in bacteria
CRH11_RS17260	COG0439	Biotin carboxylase
CRH11_RS17265	COG0511	ligase activity, forming carbon-carbon bonds
CRH11_RS17305	COG3854	ATPases associated with a variety of cellular activities
CRH11_RS17320	COG0006	proline dipeptidase activity
CRH11_RS17330	COG3872	metal-dependent enzyme
CRH11_RS17340	COG1752	Esterase of the alpha-beta hydrolase superfamily
CRH11_RS17355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRH11_RS17375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CRH11_RS17390	COG1396	sequence-specific DNA binding
CRH11_RS17400	COG0681	Belongs to the peptidase S26 family
CRH11_RS17425	COG4940	Competence protein ComGF
CRH11_RS17435	COG4970	Tfp pilus assembly protein FimT
CRH11_RS17440	COG4537	Required for transformation and DNA binding
CRH11_RS17445	COG1459	type II secretion system
CRH11_RS17450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CRH11_RS17455	COG0598	Magnesium transport protein CorA
CRH11_RS17460	COG1253	flavin adenine dinucleotide binding
CRH11_RS17465	COG1366	Belongs to the anti-sigma-factor antagonist family
CRH11_RS17475	COG1393	Belongs to the ArsC family
CRH11_RS17485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRH11_RS17495	COG0011	TIGRFAM Protein of
CRH11_RS17505	COG2866	Carboxypeptidase
CRH11_RS17510	COG1940	carbohydrate kinase activity
CRH11_RS17515	COG4483	Protein conserved in bacteria
CRH11_RS17520	COG1757	Na H antiporter
CRH11_RS17530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CRH11_RS17545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CRH11_RS17550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CRH11_RS17555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CRH11_RS17560	COG0581	inorganic phosphate transmembrane transporter activity
CRH11_RS17565	COG0573	inorganic phosphate transmembrane transporter activity
CRH11_RS17570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CRH11_RS17575	COG0768	penicillin binding
CRH11_RS17580	COG0477	Major facilitator Superfamily
CRH11_RS17585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CRH11_RS17590	COG2839	Protein conserved in bacteria
CRH11_RS17595	COG5521	maltodextrose utilization protein MalA
CRH11_RS17600	COG1388	LysM domain
CRH11_RS17610	COG4709	membrane
CRH11_RS17615	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CRH11_RS17620	COG0735	belongs to the Fur family
CRH11_RS17625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRH11_RS17640	COG0513	Belongs to the DEAD box helicase family
CRH11_RS17655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CRH11_RS17660	COG2384	SAM-dependent methyltransferase
CRH11_RS17665	COG2010	Cytochrome c
CRH11_RS17670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CRH11_RS17675	COG0358	DNA primase activity
CRH11_RS17690	COG0517	IMP dehydrogenase activity
CRH11_RS17695	COG0751	glycine-tRNA ligase activity
CRH11_RS17715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CRH11_RS17720	COG0295	cytidine deaminase activity
CRH11_RS17725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CRH11_RS17735	COG1480	7TM receptor with intracellular HD hydrolase
CRH11_RS17740	COG1702	phosphate starvation-inducible protein PhoH
CRH11_RS17745	COG0561	phosphatase activity
CRH11_RS17760	COG4864	UPF0365 protein
CRH11_RS17765	COG1030	water channel activity
CRH11_RS17770	COG1610	YqeY-like protein
CRH11_RS17780	COG1283	sodium-dependent phosphate transmembrane transporter activity
CRH11_RS17785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CRH11_RS17790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CRH11_RS17820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CRH11_RS17835	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS17850	COG1466	dna polymerase III delta subunit
CRH11_RS17860	COG2333	competence protein COMEC
CRH11_RS17860	COG0658	competence protein
CRH11_RS17865	COG2131	deaminase
CRH11_RS17870	COG1555	photosystem II stabilization
CRH11_RS17870	COG1596	polysaccharide export
CRH11_RS17875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CRH11_RS17880	COG2226	methyltransferase
CRH11_RS17885	COG0799	negative regulation of ribosome biogenesis
CRH11_RS17890	COG1713	HD superfamily hydrolase involved in NAD metabolism
CRH11_RS17900	COG1534	Rna-binding protein
CRH11_RS17905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CRH11_RS17910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CRH11_RS17915	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CRH11_RS17925	COG2755	lipolytic protein G-D-S-L family
CRH11_RS17935	COG0398	Pfam SNARE associated Golgi protein
CRH11_RS17980	COG5002	protein histidine kinase activity
CRH11_RS17980	COG0642	Histidine kinase
CRH11_RS17985	COG0745	RESPONSE REGULATOR receiver
CRH11_RS17990	COG2311	Membrane
CRH11_RS17995	COG0454	-acetyltransferase
CRH11_RS18000	COG0563	adenylate kinase activity
CRH11_RS18015	COG0456	acetyltransferase
CRH11_RS18020	COG2318	DinB family
CRH11_RS18030	COG0561	phosphatase activity
CRH11_RS18035	COG0561	phosphatase activity
CRH11_RS18045	COG1482	cell wall glycoprotein biosynthetic process
CRH11_RS18050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRH11_RS18050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRH11_RS18050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRH11_RS18055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRH11_RS18055	COG3711	transcriptional antiterminator
CRH11_RS18065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CRH11_RS18070	COG0583	DNA-binding transcription factor activity
CRH11_RS18075	COG2814	Major facilitator Superfamily
CRH11_RS18080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CRH11_RS18080	COG2124	cytochrome p450
CRH11_RS18085	COG1309	transcriptional regulator
CRH11_RS18090	COG2226	methyltransferase
CRH11_RS18105	COG2116	formate transmembrane transporter activity
CRH11_RS18110	COG5609	conserved protein (DUF2294)
CRH11_RS18115	COG3383	formate dehydrogenase (NAD+) activity
CRH11_RS18120	COG2427	Protein of unknown function (DUF1641)
CRH11_RS18130	COG0626	cystathionine gamma-synthase activity
CRH11_RS18135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CRH11_RS18160	COG0768	penicillin binding
CRH11_RS18175	COG0826	peptidase U32
CRH11_RS18180	COG0826	peptidase U32
CRH11_RS18185	COG4122	O-methyltransferase activity
CRH11_RS18190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CRH11_RS18205	COG4472	Bacterial protein of unknown function (DUF965)
CRH11_RS18215	COG0628	permease
CRH11_RS18220	COG1126	abc transporter atp-binding protein
CRH11_RS18225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRH11_RS18230	COG0765	amino acid transport
CRH11_RS18235	COG0765	amino acid transport
CRH11_RS18250	COG3881	PFAM PRC-barrel domain
CRH11_RS18255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CRH11_RS18260	COG0457	Tetratricopeptide repeat
CRH11_RS18270	COG1104	cysteine desulfurase activity
CRH11_RS18275	COG1959	2 iron, 2 sulfur cluster binding
CRH11_RS18280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CRH11_RS18285	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CRH11_RS18310	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS18310	COG4991	sh3 domain protein
CRH11_RS18310	COG3103	Sh3 type 3 domain protein
CRH11_RS18320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CRH11_RS18330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CRH11_RS18330	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CRH11_RS18335	COG5416	Lipopolysaccharide assembly protein A domain
CRH11_RS18340	COG0490	domain, Protein
CRH11_RS18345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CRH11_RS18345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CRH11_RS18355	COG2244	polysaccharide biosynthetic process
CRH11_RS18360	COG2323	membrane
CRH11_RS18370	COG1862	Preprotein translocase
CRH11_RS18415	COG1388	LysM domain
CRH11_RS18425	COG0157	Belongs to the NadC ModD family
CRH11_RS18430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CRH11_RS18435	COG1104	cysteine desulfurase activity
CRH11_RS18440	COG1827	regulation of RNA biosynthetic process
CRH11_RS18445	COG0077	Prephenate dehydratase
CRH11_RS18460	COG3290	protein histidine kinase activity
CRH11_RS18465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CRH11_RS18470	COG2868	ribosomal protein
CRH11_RS18480	COG1994	Peptidase M50
CRH11_RS18485	COG0739	heme binding
CRH11_RS18490	COG2894	cell division
CRH11_RS18500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CRH11_RS18510	COG1077	Cell shape determining protein MreB Mrl
CRH11_RS18530	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CRH11_RS18535	COG0285	dihydrofolate synthase activity
CRH11_RS18540	COG0525	valine-tRNA ligase activity
CRH11_RS18550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CRH11_RS18555	COG1388	LysM domain
CRH11_RS18565	COG0113	porphobilinogen synthase activity
CRH11_RS18570	COG1587	Uroporphyrinogen-III synthase
CRH11_RS18580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CRH11_RS18600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CRH11_RS18605	COG1067	ATP-dependent peptidase activity
CRH11_RS18605	COG0470	DNA polymerase III
CRH11_RS18620	COG1477	protein flavinylation
CRH11_RS18620	COG0457	Tetratricopeptide repeat
CRH11_RS18635	COG0473	3-isopropylmalate dehydrogenase activity
CRH11_RS18650	COG0440	acetolactate synthase activity
CRH11_RS18655	COG0028	Belongs to the TPP enzyme family
CRH11_RS18695	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CRH11_RS18715	COG0622	Phosphoesterase
CRH11_RS18720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CRH11_RS18730	COG5401	PFAM Sporulation and spore germination
CRH11_RS18740	COG1846	Transcriptional regulator
CRH11_RS18745	COG2197	response regulator
CRH11_RS18750	COG0824	Thioesterase
CRH11_RS18755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CRH11_RS18760	COG1053	succinate dehydrogenase
CRH11_RS18765	COG2009	succinate dehydrogenase
CRH11_RS18770	COG1719	4-vinyl reductase, 4VR
CRH11_RS18775	COG0527	aspartate kinase activity
CRH11_RS18790	COG3118	belongs to the thioredoxin family
CRH11_RS18795	COG3534	alpha-L-arabinofuranosidase
CRH11_RS18800	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CRH11_RS18805	COG2086	electron transfer activity
CRH11_RS18810	COG1024	Enoyl-CoA hydratase
CRH11_RS18815	COG1309	transcriptional regulator
CRH11_RS18820	COG0318	PFAM AMP-dependent synthetase and ligase
CRH11_RS18835	COG3766	membrane
CRH11_RS18845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CRH11_RS18845	COG1796	DNA polymerase
CRH11_RS18850	COG1286	toxin biosynthetic process
CRH11_RS18865	COG0072	phenylalanine-tRNA ligase activity
CRH11_RS18865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRH11_RS18870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CRH11_RS18875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CRH11_RS18885	COG3835	regulator
CRH11_RS18890	COG0277	FAD linked oxidase domain protein
CRH11_RS18895	COG0247	lactate metabolic process
CRH11_RS18900	COG1966	Carbon starvation protein
CRH11_RS18905	COG3534	alpha-L-arabinofuranosidase
CRH11_RS18910	COG0395	ABC-type sugar transport system, permease component
CRH11_RS18915	COG1175	transmembrane transport
CRH11_RS18920	COG1653	transport
CRH11_RS18930	COG0647	UMP catabolic process
CRH11_RS18935	COG0235	Class ii aldolase
CRH11_RS18940	COG1069	ribulokinase activity
CRH11_RS18945	COG2160	L-arabinose isomerase activity
CRH11_RS18950	COG3507	Belongs to the glycosyl hydrolase 43 family
CRH11_RS18955	COG1363	Peptidase, m42
CRH11_RS18965	COG3326	Membrane
CRH11_RS18980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CRH11_RS18985	COG1346	cytolysis
CRH11_RS18990	COG1380	Effector of murein hydrolase LrgA
CRH11_RS18995	COG3279	Response regulator of the LytR AlgR family
CRH11_RS19000	COG3275	phosphorelay sensor kinase activity
CRH11_RS19005	COG1011	Hydrolase
CRH11_RS19020	COG0398	Pfam SNARE associated Golgi protein
CRH11_RS19025	COG1484	DNA-dependent DNA replication
CRH11_RS19030	COG3611	Membrane attachment protein
CRH11_RS19045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CRH11_RS19050	COG1733	regulation of RNA biosynthetic process
CRH11_RS19055	COG2814	Major facilitator Superfamily
CRH11_RS19060	COG0656	L-ascorbic acid biosynthetic process
CRH11_RS19065	COG0237	dephospho-CoA kinase activity
CRH11_RS19070	COG1971	Probably functions as a manganese efflux pump
CRH11_RS19075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CRH11_RS19080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRH11_RS19080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRH11_RS19085	COG5002	protein histidine kinase activity
CRH11_RS19090	COG0745	RESPONSE REGULATOR receiver
CRH11_RS19100	COG0538	isocitrate dehydrogenase activity
CRH11_RS19105	COG0372	Belongs to the citrate synthase family
CRH11_RS19110	COG0457	Tetratricopeptide repeat
CRH11_RS19140	COG0628	permease
CRH11_RS19145	COG3030	protein affecting phage T7 exclusion by the F plasmid
CRH11_RS19150	COG0469	pyruvate kinase activity
CRH11_RS19170	COG0281	malic enzyme
CRH11_RS19175	COG0587	DNA-directed DNA polymerase activity
CRH11_RS19195	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CRH11_RS19205	COG4109	DRTGG domain
CRH11_RS19215	COG1028	Short-chain dehydrogenase reductase Sdr
CRH11_RS19235	COG0521	Mo-molybdopterin cofactor biosynthetic process
CRH11_RS19245	COG0827	DNA restriction-modification system
CRH11_RS19250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CRH11_RS19255	COG3874	Sporulation protein YtfJ
CRH11_RS19265	COG1714	RDD family
CRH11_RS19270	COG0616	signal peptide processing
CRH11_RS19275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CRH11_RS19280	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CRH11_RS19285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CRH11_RS19300	COG1104	cysteine desulfurase activity
CRH11_RS19305	COG1114	Component of the transport system for branched-chain amino acids
CRH11_RS19315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CRH11_RS19320	COG1309	transcriptional regulator
CRH11_RS19325	COG1956	GAF domain-containing protein
CRH11_RS19330	COG2199	diguanylate cyclase activity
CRH11_RS19330	COG2203	Gaf domain
CRH11_RS19345	COG1012	belongs to the aldehyde dehydrogenase family
CRH11_RS19375	COG0582	viral genome integration into host DNA
CRH11_RS19380	COG1017	nitric oxide dioxygenase activity
CRH11_RS19380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRH11_RS19390	COG0693	protein deglycase activity
CRH11_RS19405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CRH11_RS19410	COG1378	Sugar-specific transcriptional regulator TrmB
CRH11_RS19430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CRH11_RS19435	COG0454	-acetyltransferase
CRH11_RS19440	COG0517	IMP dehydrogenase activity
CRH11_RS19445	COG0123	including yeast histone deacetylase and acetoin utilization protein
CRH11_RS19450	COG1360	Flagellar Motor Protein
CRH11_RS19455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CRH11_RS19460	COG1609	Transcriptional regulator
CRH11_RS19465	COG1605	Chorismate mutase
CRH11_RS19465	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CRH11_RS19470	COG3118	belongs to the thioredoxin family
CRH11_RS19475	COG4980	gas vesicle protein
CRH11_RS19480	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CRH11_RS19490	COG1674	ftsk spoiiie
CRH11_RS19495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRH11_RS19505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRH11_RS19515	COG1363	Peptidase, m42
CRH11_RS19520	COG5584	Small secreted protein
CRH11_RS19525	COG0281	malic enzyme
CRH11_RS19530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRH11_RS19545	COG0510	thiamine kinase activity
CRH11_RS19550	COG1597	lipid kinase activity
CRH11_RS19560	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CRH11_RS19565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CRH11_RS19570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRH11_RS19575	COG2252	PERMEase
CRH11_RS19580	COG4473	ABC transporter
CRH11_RS19585	COG1131	(ABC) transporter
CRH11_RS19590	COG1349	DNA-binding transcription factor activity
CRH11_RS19595	COG1187	pseudouridine synthase activity
CRH11_RS19600	COG2244	polysaccharide biosynthetic process
CRH11_RS19605	COG2081	HI0933 family
CRH11_RS19610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CRH11_RS19620	COG1609	Transcriptional regulator
CRH11_RS19625	COG1653	transport
CRH11_RS19630	COG1175	transmembrane transport
CRH11_RS19635	COG0395	ABC-type sugar transport system, permease component
CRH11_RS19640	COG1486	melibiose metabolic process
CRH11_RS19650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRH11_RS19665	COG1366	Belongs to the anti-sigma-factor antagonist family
CRH11_RS19665	COG2202	Pas domain
CRH11_RS19670	COG2814	Major facilitator Superfamily
CRH11_RS19675	COG5522	Integral membrane protein (intg_mem_TP0381)
CRH11_RS19680	COG0577	efflux transmembrane transporter activity
CRH11_RS19685	COG1136	(ABC) transporter
CRH11_RS19690	COG2205	protein histidine kinase activity
CRH11_RS19695	COG0745	RESPONSE REGULATOR receiver
CRH11_RS19700	COG0577	efflux transmembrane transporter activity
CRH11_RS19705	COG1136	(ABC) transporter
CRH11_RS19725	COG1131	(ABC) transporter
CRH11_RS19730	COG1725	Transcriptional regulator
CRH11_RS19740	COG0640	Transcriptional regulator
CRH11_RS19745	COG0477	Major facilitator Superfamily
CRH11_RS19750	COG1242	4 iron, 4 sulfur cluster binding
CRH11_RS19755	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CRH11_RS19765	COG0584	glycerophosphoryl diester phosphodiesterase
CRH11_RS19775	COG2267	carboxylic ester hydrolase activity
CRH11_RS19780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CRH11_RS19785	COG1113	amino acid transport
CRH11_RS19790	COG0367	asparagine synthase
CRH11_RS19810	COG1506	peptidase
CRH11_RS19815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CRH11_RS19820	COG1116	anion transmembrane transporter activity
CRH11_RS19825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CRH11_RS19830	COG0494	nUDIX hydrolase
CRH11_RS19835	COG4824	toxin secretion phage lysis holin
CRH11_RS19840	COG0783	Belongs to the Dps family
CRH11_RS19865	COG0288	reversible hydration of carbon dioxide
CRH11_RS19875	COG1271	oxidase subunit
CRH11_RS19880	COG1294	oxidase, subunit
CRH11_RS19895	COG4948	Mandelate Racemase Muconate Lactonizing
CRH11_RS19905	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CRH11_RS19910	COG0596	Alpha beta hydrolase
CRH11_RS19920	COG1169	isochorismate synthase
CRH11_RS19925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CRH11_RS19930	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CRH11_RS20055	COG3859	Proton-coupled thiamine transporter YuaJ
CRH11_RS20060	COG2268	Band 7 protein
CRH11_RS20065	COG1585	Membrane protein implicated in regulation of membrane protease activity
CRH11_RS20070	COG2318	DinB family
CRH11_RS20085	COG1454	alcohol dehydrogenase
CRH11_RS20090	COG1012	belongs to the aldehyde dehydrogenase family
CRH11_RS20095	COG1510	regulation of RNA biosynthetic process
CRH11_RS20105	COG0569	domain protein
CRH11_RS20110	COG1705	Flagellar rod assembly protein muramidase FlgJ
CRH11_RS20115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRH11_RS20115	COG1017	nitric oxide dioxygenase activity
CRH11_RS20155	COG1388	LysM domain
CRH11_RS20155	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS20155	COG5632	N-Acetylmuramoyl-L-alanine amidase
CRH11_RS20180	COG5434	Belongs to the glycosyl hydrolase 28 family
CRH11_RS20190	COG1705	Flagellar rod assembly protein muramidase FlgJ
CRH11_RS20285	COG0582	viral genome integration into host DNA
CRH11_RS20305	COG1216	Glycosyl transferase, family 2
CRH11_RS20315	COG4195	phage-related replication protein
CRH11_RS20320	COG3420	alginic acid biosynthetic process
CRH11_RS20320	COG5434	Belongs to the glycosyl hydrolase 28 family
CRH11_RS20350	COG1595	DNA-templated transcription, initiation
CRH11_RS20380	COG3584	3D domain protein
CRH11_RS20380	COG1388	LysM domain
CRH11_RS20385	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CRH11_RS20400	COG0756	dUTP diphosphatase activity
CRH11_RS20405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRH11_RS20415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRH11_RS20420	COG1780	Probably involved in ribonucleotide reductase function
CRH11_RS20460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRH11_RS20460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRH11_RS20505	COG3655	Transcriptional regulator
CRH11_RS20535	COG1484	DNA-dependent DNA replication
CRH11_RS20580	COG4974	Belongs to the 'phage' integrase family
CRH11_RS20610	COG1388	LysM domain
CRH11_RS20610	COG3409	Peptidoglycan-binding domain 1 protein
CRH11_RS20610	COG5632	N-Acetylmuramoyl-L-alanine amidase