locus-tag	class	description
EYS44_RS00010	COG0592	DNA-directed DNA polymerase activity
EYS44_RS00015	COG2501	S4 domain
EYS44_RS00030	COG0187	DNA topoisomerase II activity
EYS44_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYS44_RS00070	COG0517	IMP dehydrogenase activity
EYS44_RS00070	COG0516	GMP reductase activity
EYS44_RS00075	COG1686	Belongs to the peptidase S11 family
EYS44_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
EYS44_RS00105	COG1428	Deoxynucleoside kinase
EYS44_RS00110	COG1428	Deoxynucleoside kinase
EYS44_RS00115	COG1388	LysM domain
EYS44_RS00115	COG3858	chitin binding
EYS44_RS00120	COG1335	isochorismatase
EYS44_RS00125	COG0590	tRNA wobble adenosine to inosine editing
EYS44_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EYS44_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYS44_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EYS44_RS00195	COG3853	Toxic anion resistance protein (TelA)
EYS44_RS00200	COG1982	Orn Lys Arg decarboxylase major
EYS44_RS00210	COG3870	Protein conserved in bacteria
EYS44_RS00215	COG1728	Protein conserved in bacteria
EYS44_RS00220	COG0470	DNA polymerase III
EYS44_RS00225	COG1774	PSP1 C-terminal conserved region
EYS44_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EYS44_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYS44_RS00250	COG2002	toxin-antitoxin pair type II binding
EYS44_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS44_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS44_RS00260	COG0084	hydrolase, TatD family'
EYS44_RS00265	COG3583	domain protein
EYS44_RS00265	COG3584	3D domain protein
EYS44_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EYS44_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYS44_RS00285	COG4466	Protein conserved in bacteria
EYS44_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYS44_RS00305	COG0251	oxidation-reduction process
EYS44_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYS44_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYS44_RS00345	COG2002	toxin-antitoxin pair type II binding
EYS44_RS00350	COG2244	polysaccharide biosynthetic process
EYS44_RS00355	COG3956	TIGRFAM MazG family protein
EYS44_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EYS44_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EYS44_RS00380	COG1098	S1 RNA binding domain
EYS44_RS00395	COG2208	phosphoserine phosphatase activity
EYS44_RS00400	COG2304	oxidoreductase activity
EYS44_RS00405	COG0515	serine threonine protein kinase
EYS44_RS00410	COG0037	tRNA processing
EYS44_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EYS44_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYS44_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYS44_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYS44_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYS44_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
EYS44_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYS44_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYS44_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYS44_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYS44_RS00475	COG1396	sequence-specific DNA binding
EYS44_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYS44_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EYS44_RS00565	COG4463	regulation of RNA biosynthetic process
EYS44_RS00570	COG3880	PFAM UvrB UvrC protein
EYS44_RS00580	COG0542	response to heat
EYS44_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EYS44_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EYS44_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
EYS44_RS00620	COG1045	serine acetyltransferase
EYS44_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EYS44_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYS44_RS00640	COG3688	RNA-binding protein containing a PIN domain
EYS44_RS00645	COG1595	DNA-templated transcription, initiation
EYS44_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYS44_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
EYS44_RS00685	COG2813	Specifically methylates the guanine in position
EYS44_RS00700	COG1358	cellular component organization or biogenesis
EYS44_RS00725	COG0596	Alpha beta hydrolase
EYS44_RS00835	COG0201	protein transport
EYS44_RS00845	COG0024	Methionine aminopeptidase
EYS44_RS00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EYS44_RS00885	COG1122	ATPase activity
EYS44_RS00890	COG1122	ATPase activity
EYS44_RS00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EYS44_RS00915	COG2226	methyltransferase
EYS44_RS00920	COG2318	DinB family
EYS44_RS00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS00935	COG0489	protein tyrosine kinase activity
EYS44_RS00945	COG2194	sulfuric ester hydrolase activity
EYS44_RS00950	COG0726	polysaccharide deacetylase
EYS44_RS01010	COG0738	Major facilitator superfamily
EYS44_RS01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EYS44_RS01030	COG0659	secondary active sulfate transmembrane transporter activity
EYS44_RS01035	COG0385	Bile acid
EYS44_RS01040	COG2819	hydrolase of the alpha beta superfamily
EYS44_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS44_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS44_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYS44_RS01060	COG2207	Transcriptional regulator
EYS44_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYS44_RS01065	COG3876	Protein conserved in bacteria
EYS44_RS01070	COG1472	Belongs to the glycosyl hydrolase 3 family
EYS44_RS01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYS44_RS01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYS44_RS01080	COG1263	PTS System
EYS44_RS01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYS44_RS01095	COG1683	Conserved Protein
EYS44_RS01125	COG1595	DNA-templated transcription, initiation
EYS44_RS01130	COG5662	AntiSigma factor
EYS44_RS01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EYS44_RS01140	COG4856	YbbR-like protein
EYS44_RS01180	COG1346	cytolysis
EYS44_RS01185	COG1380	Effector of murein hydrolase LrgA
EYS44_RS01190	COG1846	Transcriptional regulator
EYS44_RS01195	COG1113	amino acid transport
EYS44_RS01200	COG1011	Hydrolase
EYS44_RS01205	COG4585	Histidine kinase
EYS44_RS01210	COG2197	response regulator
EYS44_RS01215	COG1131	(ABC) transporter
EYS44_RS01235	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EYS44_RS01255	COG3321	synthase
EYS44_RS01255	COG4221	oxidoreductase activity
EYS44_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS01255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS01260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS01260	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS01260	COG0300	oxidoreductase activity
EYS44_RS01260	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS01260	COG3321	synthase
EYS44_RS01300	COG0531	amino acid
EYS44_RS01305	COG0584	glycerophosphoryl diester phosphodiesterase
EYS44_RS01310	COG2271	Major facilitator Superfamily
EYS44_RS01325	COG2368	4-hydroxyphenylacetate
EYS44_RS01335	COG3409	Peptidoglycan-binding domain 1 protein
EYS44_RS01350	COG0371	Dehydrogenase
EYS44_RS01360	COG1183	phosphatidylcholine synthase activity
EYS44_RS01365	COG0586	Pfam SNARE associated Golgi protein
EYS44_RS01370	COG0688	phosphatidylethanolamine metabolic process
EYS44_RS01385	COG1301	dicarboxylic acid transport
EYS44_RS01390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYS44_RS01395	COG0833	amino acid
EYS44_RS01400	COG2040	homocysteine
EYS44_RS01405	COG1115	amino acid carrier protein
EYS44_RS01410	COG2066	Belongs to the glutaminase family
EYS44_RS01415	COG4191	Histidine kinase
EYS44_RS01420	COG0784	Response regulator, receiver
EYS44_RS01425	COG3173	Aminoglycoside phosphotransferase
EYS44_RS01435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYS44_RS01440	COG0778	Nitroreductase
EYS44_RS01445	COG0346	lactoylglutathione lyase activity
EYS44_RS01450	COG2259	Doxx family
EYS44_RS01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYS44_RS01470	COG3773	Cell wall hydrolase
EYS44_RS01480	COG3540	Alkaline phosphatase
EYS44_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYS44_RS01490	COG0805	protein transport
EYS44_RS01500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYS44_RS01505	COG0477	Major facilitator Superfamily
EYS44_RS01510	COG1309	transcriptional regulator
EYS44_RS01515	COG0252	asparaginase activity
EYS44_RS01520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EYS44_RS01525	COG1405	negative regulation of cell septum assembly
EYS44_RS01525	COG3012	SEC-C Motif Domain Protein
EYS44_RS01530	COG0667	Aldo Keto reductase
EYS44_RS01540	COG1595	DNA-templated transcription, initiation
EYS44_RS01545	COG1595	DNA-templated transcription, initiation
EYS44_RS01550	COG1876	peptidase activity
EYS44_RS01555	COG0457	Tetratricopeptide repeat
EYS44_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS01565	COG0366	Alpha amylase catalytic
EYS44_RS01570	COG0803	Belongs to the bacterial solute-binding protein 9 family
EYS44_RS01575	COG1121	(ABC) transporter
EYS44_RS01580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYS44_RS01585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYS44_RS01590	COG2310	stress, protein
EYS44_RS01595	COG2310	stress, protein
EYS44_RS01600	COG2310	stress, protein
EYS44_RS01605	COG0861	Integral membrane protein TerC family
EYS44_RS01615	COG3853	Toxic anion resistance protein (TelA)
EYS44_RS01620	COG0477	Major facilitator Superfamily
EYS44_RS01625	COG4175	Glycine betaine
EYS44_RS01625	COG0517	IMP dehydrogenase activity
EYS44_RS01630	COG4176	ABC-type proline glycine betaine transport system permease component
EYS44_RS01635	COG2113	Glycine betaine
EYS44_RS01640	COG1473	amidohydrolase
EYS44_RS01645	COG1288	antiporter activity
EYS44_RS01655	COG0366	Alpha amylase catalytic
EYS44_RS01665	COG2814	Major facilitator Superfamily
EYS44_RS01670	COG1846	Transcriptional regulator
EYS44_RS01675	COG1280	lysine exporter protein (LysE YggA)
EYS44_RS01680	COG3403	YqcI/YcgG family
EYS44_RS01685	COG1113	amino acid transport
EYS44_RS01690	COG3665	Urea carboxylase-associated protein
EYS44_RS01705	COG1660	Displays ATPase and GTPase activities
EYS44_RS01715	COG2271	Major facilitator Superfamily
EYS44_RS01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYS44_RS01725	COG3458	cephalosporin-C deacetylase activity
EYS44_RS01730	COG3541	Predicted nucleotidyltransferase
EYS44_RS01735	COG0506	proline dehydrogenase activity
EYS44_RS01740	COG1012	belongs to the aldehyde dehydrogenase family
EYS44_RS01745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYS44_RS01750	COG2508	Transcriptional regulator
EYS44_RS01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYS44_RS01760	COG1587	Uroporphyrinogen-III synthase
EYS44_RS01765	COG2146	nitrite reductase [NAD(P)H] activity
EYS44_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYS44_RS01780	COG0523	cobalamin synthesis protein
EYS44_RS01785	COG1063	alcohol dehydrogenase
EYS44_RS01790	COG1714	RDD family
EYS44_RS01800	COG2723	6-phospho-beta-galactosidase activity
EYS44_RS01815	COG3209	COG3209 Rhs family protein
EYS44_RS01820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EYS44_RS01825	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EYS44_RS01830	COG1733	regulation of RNA biosynthetic process
EYS44_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS01850	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EYS44_RS01865	COG2364	Membrane
EYS44_RS01870	COG1126	abc transporter atp-binding protein
EYS44_RS01875	COG0765	amino acid transport
EYS44_RS01880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYS44_RS01885	COG0583	DNA-binding transcription factor activity
EYS44_RS01890	COG0163	prenyltransferase activity
EYS44_RS01895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EYS44_RS01910	COG3104	oligopeptide transport
EYS44_RS01915	COG5434	Belongs to the glycosyl hydrolase 28 family
EYS44_RS01925	COG0697	spore germination
EYS44_RS01935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EYS44_RS01940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYS44_RS01945	COG0456	acetyltransferase
EYS44_RS01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYS44_RS01955	COG0765	amino acid transport
EYS44_RS01960	COG1126	abc transporter atp-binding protein
EYS44_RS01965	COG1473	amidohydrolase
EYS44_RS01970	COG2079	MmgE PrpD family protein
EYS44_RS01975	COG1136	(ABC) transporter
EYS44_RS01980	COG0577	efflux transmembrane transporter activity
EYS44_RS01985	COG0745	RESPONSE REGULATOR receiver
EYS44_RS01990	COG5002	protein histidine kinase activity
EYS44_RS01990	COG3850	Histidine kinase
EYS44_RS01995	COG0457	Tetratricopeptide repeat
EYS44_RS02010	COG0527	aspartate kinase activity
EYS44_RS02015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS44_RS02020	COG4605	iron ion homeostasis
EYS44_RS02025	COG4604	ABC transporter, ATP-binding protein
EYS44_RS02030	COG4607	ABC-type enterochelin transport system periplasmic component
EYS44_RS02035	COG2814	Major facilitator Superfamily
EYS44_RS02040	COG1309	transcriptional regulator
EYS44_RS02045	COG0778	Nitroreductase
EYS44_RS02050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EYS44_RS02055	COG0640	Transcriptional regulator
EYS44_RS02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYS44_RS02065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EYS44_RS02070	COG1012	belongs to the aldehyde dehydrogenase family
EYS44_RS02075	COG4975	Glucose uptake
EYS44_RS02080	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS02085	COG4549	nuclear export factor GLE1
EYS44_RS02090	COG1276	copper resistance
EYS44_RS02090	COG2372	response to copper ion
EYS44_RS02095	COG1349	DNA-binding transcription factor activity
EYS44_RS02105	COG2213	PTS system mannitol-specific
EYS44_RS02110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS44_RS02120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYS44_RS02130	COG0561	phosphatase activity
EYS44_RS02140	COG1914	H( )-stimulated, divalent metal cation uptake system
EYS44_RS02150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EYS44_RS02155	COG1984	allophanate hydrolase subunit 2
EYS44_RS02160	COG1414	Transcriptional regulator
EYS44_RS02165	COG2755	lipolytic protein G-D-S-L family
EYS44_RS02175	COG2329	Antibiotic biosynthesis monooxygenase
EYS44_RS02180	COG0768	penicillin binding
EYS44_RS02185	COG4989	oxidoreductase activity
EYS44_RS02190	COG3711	transcriptional antiterminator
EYS44_RS02195	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS02200	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS02205	COG1917	Cupin 2, conserved barrel domain protein
EYS44_RS02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYS44_RS02215	COG3871	stress protein (general stress protein 26)
EYS44_RS02225	COG2814	Major facilitator Superfamily
EYS44_RS02230	COG1522	sequence-specific DNA binding
EYS44_RS02235	COG0551	DNA topoisomerase type I activity
EYS44_RS02235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYS44_RS02240	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EYS44_RS02245	COG3706	GGDEF domain
EYS44_RS02250	COG5298	Protein conserved in bacteria
EYS44_RS02255	COG1215	transferase activity, transferring glycosyl groups
EYS44_RS02265	COG0531	amino acid
EYS44_RS02270	COG0494	nUDIX hydrolase
EYS44_RS02275	COG0028	Belongs to the TPP enzyme family
EYS44_RS02305	COG1914	H( )-stimulated, divalent metal cation uptake system
EYS44_RS02320	COG4876	unkown
EYS44_RS02330	COG2076	Multidrug Resistance protein
EYS44_RS02335	COG2217	Heavy metal translocating P-type atpase
EYS44_RS02340	COG3729	General stress protein
EYS44_RS02345	COG0662	Cupin 2, conserved barrel domain protein
EYS44_RS02350	COG2329	Antibiotic biosynthesis monooxygenase
EYS44_RS02355	COG3546	catalase activity
EYS44_RS02360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYS44_RS02365	COG3290	protein histidine kinase activity
EYS44_RS02370	COG4565	transcriptional regulatory protein
EYS44_RS02375	COG1301	dicarboxylic acid transport
EYS44_RS02380	COG0628	permease
EYS44_RS02385	COG1131	(ABC) transporter
EYS44_RS02390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EYS44_RS02400	COG1960	acyl-CoA dehydrogenase activity
EYS44_RS02415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYS44_RS02420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYS44_RS02430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYS44_RS02435	COG0513	Belongs to the DEAD box helicase family
EYS44_RS02440	COG3402	PFAM membrane-flanked domain
EYS44_RS02445	COG3428	Bacterial PH domain
EYS44_RS02450	COG0705	Rhomboid family
EYS44_RS02460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EYS44_RS02465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYS44_RS02470	COG0864	Transcriptional regulator
EYS44_RS02475	COG2337	Toxic component of a toxin-antitoxin (TA) module
EYS44_RS02480	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS44_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS44_RS02490	COG2172	sigma factor antagonist activity
EYS44_RS02495	COG2208	phosphoserine phosphatase activity
EYS44_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS44_RS02510	COG1191	sigma factor activity
EYS44_RS02515	COG2208	phosphoserine phosphatase activity
EYS44_RS02520	COG2183	response to ionizing radiation
EYS44_RS02570	COG2249	NAD(P)H dehydrogenase (quinone) activity
EYS44_RS02585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EYS44_RS02590	COG0477	Major facilitator Superfamily
EYS44_RS02600	COG1764	response to oxidative stress
EYS44_RS02605	COG1846	Transcriptional regulator
EYS44_RS02615	COG1959	2 iron, 2 sulfur cluster binding
EYS44_RS02620	COG2910	NAD(P)H-binding
EYS44_RS02625	COG1278	Cold shock
EYS44_RS02630	COG1329	Transcriptional regulator
EYS44_RS02635	COG1937	Protein conserved in bacteria
EYS44_RS02640	COG2210	Belongs to the sulfur carrier protein TusA family
EYS44_RS02650	COG0425	Belongs to the sulfur carrier protein TusA family
EYS44_RS02650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYS44_RS02655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYS44_RS02655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYS44_RS02660	COG0425	Belongs to the sulfur carrier protein TusA family
EYS44_RS02665	COG0730	response to heat
EYS44_RS02670	COG1794	racemase activity, acting on amino acids and derivatives
EYS44_RS02685	COG3621	Patatin-like phospholipase
EYS44_RS02695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYS44_RS02700	COG1802	Transcriptional regulator
EYS44_RS02705	COG0251	oxidation-reduction process
EYS44_RS02710	COG0814	amino acid
EYS44_RS02715	COG1473	amidohydrolase
EYS44_RS02720	COG1917	Cupin 2, conserved barrel domain protein
EYS44_RS02720	COG2207	Transcriptional regulator
EYS44_RS02730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYS44_RS02735	COG0477	Major facilitator Superfamily
EYS44_RS02755	COG0277	FAD linked oxidase domain protein
EYS44_RS02790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYS44_RS02815	COG1064	alcohol dehydrogenase
EYS44_RS02820	COG0789	Transcriptional regulator
EYS44_RS02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYS44_RS02845	COG2814	Major facilitator Superfamily
EYS44_RS02850	COG1309	transcriptional regulator
EYS44_RS02860	COG5577	PFAM Coat F domain
EYS44_RS02870	COG1063	alcohol dehydrogenase
EYS44_RS02875	COG5577	PFAM Coat F domain
EYS44_RS02885	COG4585	Histidine kinase
EYS44_RS02890	COG2197	response regulator
EYS44_RS02895	COG2409	Drug exporters of the RND superfamily
EYS44_RS02900	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYS44_RS02905	COG0488	(ABC) transporter
EYS44_RS02910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYS44_RS02915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYS44_RS02925	COG2814	Major facilitator Superfamily
EYS44_RS02930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYS44_RS02940	COG0730	response to heat
EYS44_RS02945	COG0456	acetyltransferase
EYS44_RS02950	COG0789	Transcriptional regulator
EYS44_RS02950	COG4978	Transcriptional regulator
EYS44_RS02955	COG0697	spore germination
EYS44_RS02960	COG1051	belongs to the nudix hydrolase family
EYS44_RS02965	COG2226	methyltransferase
EYS44_RS02970	COG0473	3-isopropylmalate dehydrogenase activity
EYS44_RS02975	COG1802	Transcriptional regulator
EYS44_RS02980	COG1819	glycosyl
EYS44_RS02995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYS44_RS03000	COG1388	LysM domain
EYS44_RS03005	COG2814	Major facilitator Superfamily
EYS44_RS03010	COG2188	Transcriptional regulator
EYS44_RS03015	COG2186	Transcriptional regulator
EYS44_RS03020	COG2807	transmembrane transport
EYS44_RS03025	COG2076	Multidrug Resistance protein
EYS44_RS03030	COG2076	Multidrug Resistance protein
EYS44_RS03035	COG1309	transcriptional regulator
EYS44_RS03040	COG0531	amino acid
EYS44_RS03050	COG3832	glyoxalase III activity
EYS44_RS03055	COG0604	alcohol dehydrogenase
EYS44_RS03060	COG2814	Major facilitator Superfamily
EYS44_RS03100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EYS44_RS03105	COG0802	atpase or kinase
EYS44_RS03110	COG1214	PFAM Peptidase M22, glycoprotease
EYS44_RS03115	COG0456	acetyltransferase
EYS44_RS03120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYS44_RS03125	COG0488	(ABC) transporter
EYS44_RS03140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYS44_RS03145	COG0805	protein transport
EYS44_RS03155	COG1266	CAAX protease self-immunity
EYS44_RS03180	COG0457	Tetratricopeptide repeat
EYS44_RS03185	COG1063	alcohol dehydrogenase
EYS44_RS03190	COG2211	Major facilitator Superfamily
EYS44_RS03195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYS44_RS03205	COG1842	Phage shock protein A
EYS44_RS03210	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYS44_RS03215	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EYS44_RS03220	COG4260	virion core protein, lumpy skin disease virus
EYS44_RS03225	COG2755	lipolytic protein G-D-S-L family
EYS44_RS03225	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EYS44_RS03235	COG1595	DNA-templated transcription, initiation
EYS44_RS03240	COG1063	alcohol dehydrogenase
EYS44_RS03245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EYS44_RS03250	COG0823	Involved in the tonB-independent uptake of proteins
EYS44_RS03260	COG2132	Multicopper oxidase
EYS44_RS03265	COG1113	amino acid transport
EYS44_RS03270	COG0714	Associated with various cellular activities
EYS44_RS03275	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EYS44_RS03280	COG1305	Transglutaminase-like
EYS44_RS03300	COG2252	PERMEase
EYS44_RS03305	COG3064	Membrane
EYS44_RS03325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYS44_RS03330	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EYS44_RS03335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EYS44_RS03340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYS44_RS03345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYS44_RS03360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EYS44_RS03370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYS44_RS03375	COG0138	bifunctional purine biosynthesis protein purh
EYS44_RS03380	COG0151	Belongs to the GarS family
EYS44_RS03390	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EYS44_RS03395	COG1470	cell adhesion involved in biofilm formation
EYS44_RS03400	COG4496	protein, YerC YecD
EYS44_RS03405	COG0069	glutamate synthase activity
EYS44_RS03420	COG0210	DNA helicase
EYS44_RS03430	COG4851	CamS sex pheromone cAM373 precursor
EYS44_RS03435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EYS44_RS03440	COG1285	pathogenesis
EYS44_RS03445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYS44_RS03465	COG1309	transcriptional regulator
EYS44_RS03470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYS44_RS03475	COG1597	lipid kinase activity
EYS44_RS03480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYS44_RS03490	COG1131	(ABC) transporter
EYS44_RS03515	COG5444	nuclease activity
EYS44_RS03550	COG3546	catalase activity
EYS44_RS03555	COG0454	-acetyltransferase
EYS44_RS03565	COG2323	membrane
EYS44_RS03570	COG2329	Antibiotic biosynthesis monooxygenase
EYS44_RS03575	COG0346	lactoylglutathione lyase activity
EYS44_RS03585	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS44_RS03590	COG5583	Uncharacterized small protein (DUF2292)
EYS44_RS03595	COG0196	riboflavin kinase activity
EYS44_RS03600	COG0670	Belongs to the BI1 family
EYS44_RS03610	COG1846	Transcriptional regulator
EYS44_RS03615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYS44_RS03625	COG2124	cytochrome p450
EYS44_RS03625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYS44_RS03630	COG1368	sulfuric ester hydrolase activity
EYS44_RS03635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EYS44_RS03640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYS44_RS03645	COG1442	glycosyl transferase family 8
EYS44_RS03650	COG1216	Glycosyl transferase, family 2
EYS44_RS03655	COG1442	glycosyl transferase family 8
EYS44_RS03660	COG2223	nitrite transmembrane transporter activity
EYS44_RS03665	COG0531	amino acid
EYS44_RS03670	COG1012	belongs to the aldehyde dehydrogenase family
EYS44_RS03675	COG0840	transmembrane signaling receptor activity
EYS44_RS03680	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS03685	COG0457	Tetratricopeptide repeat
EYS44_RS03685	COG0463	Glycosyl transferase, family 2
EYS44_RS03690	COG0488	(ABC) transporter
EYS44_RS03695	COG0789	Transcriptional regulator
EYS44_RS03700	COG2814	Major facilitator Superfamily
EYS44_RS03705	COG0488	(ABC) transporter
EYS44_RS03710	COG0513	Belongs to the DEAD box helicase family
EYS44_RS03720	COG2130	NADP-dependent
EYS44_RS03735	COG3866	Pectate lyase
EYS44_RS03740	COG0471	metal ion transport
EYS44_RS03755	COG2972	Histidine kinase
EYS44_RS03755	COG0745	RESPONSE REGULATOR receiver
EYS44_RS03760	COG3279	Response regulator of the LytR AlgR family
EYS44_RS03770	COG3764	Sortase (surface protein transpeptidase)
EYS44_RS03775	COG3290	protein histidine kinase activity
EYS44_RS03780	COG4565	transcriptional regulatory protein
EYS44_RS03785	COG3181	Tripartite tricarboxylate transporter family receptor
EYS44_RS03790	COG2851	Citrate transporter
EYS44_RS03795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYS44_RS03800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EYS44_RS03810	COG2258	MOSC domain
EYS44_RS03830	COG0024	Methionine aminopeptidase
EYS44_RS03835	COG1263	PTS System
EYS44_RS03835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYS44_RS03845	COG1368	sulfuric ester hydrolase activity
EYS44_RS03855	COG0071	Belongs to the small heat shock protein (HSP20) family
EYS44_RS03870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYS44_RS03870	COG1263	PTS System
EYS44_RS03875	COG0366	Alpha amylase catalytic
EYS44_RS03880	COG2188	Transcriptional regulator
EYS44_RS03885	COG0778	Nitroreductase
EYS44_RS03900	COG0737	Belongs to the 5'-nucleotidase family
EYS44_RS03905	COG0693	protein deglycase activity
EYS44_RS03910	COG1609	Transcriptional regulator
EYS44_RS03925	COG2814	Major facilitator Superfamily
EYS44_RS03935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYS44_RS03940	COG4980	gas vesicle protein
EYS44_RS03945	COG1295	ribonuclease BN
EYS44_RS03950	COG0477	Major facilitator Superfamily
EYS44_RS03955	COG0387	Pfam Sodium calcium exchanger
EYS44_RS03965	COG0668	transmembrane transport
EYS44_RS03970	COG0535	radical SAM domain protein
EYS44_RS03980	COG0726	polysaccharide deacetylase
EYS44_RS03985	COG2084	Dehydrogenase
EYS44_RS03995	COG0598	Magnesium transport protein CorA
EYS44_RS04000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EYS44_RS04005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYS44_RS04015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYS44_RS04020	COG4637	Psort location Cytoplasmic, score
EYS44_RS04025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYS44_RS04030	COG0022	dehydrogenase e1 component
EYS44_RS04035	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYS44_RS04040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYS44_RS04045	COG3284	Transcriptional regulator
EYS44_RS04055	COG1486	melibiose metabolic process
EYS44_RS04060	COG1737	Transcriptional regulator
EYS44_RS04065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYS44_RS04065	COG1263	PTS System
EYS44_RS04070	COG1132	(ABC) transporter
EYS44_RS04075	COG1132	(ABC) transporter
EYS44_RS04080	COG2259	Doxx family
EYS44_RS04085	COG2514	catechol 2,3-dioxygenase activity
EYS44_RS04100	COG1695	Transcriptional regulator
EYS44_RS04105	COG2249	NAD(P)H dehydrogenase (quinone) activity
EYS44_RS04110	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EYS44_RS04115	COG3848	Pyruvate phosphate dikinase
EYS44_RS04115	COG0574	Belongs to the PEP-utilizing enzyme family
EYS44_RS04120	COG2732	(Barnase) inhibitor
EYS44_RS04125	COG2318	DinB family
EYS44_RS04130	COG2814	Major facilitator Superfamily
EYS44_RS04135	COG1846	Transcriptional regulator
EYS44_RS04140	COG0392	lysyltransferase activity
EYS44_RS04140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EYS44_RS04145	COG0384	phenazine biosynthesis protein PhzF
EYS44_RS04150	COG0778	Nitroreductase
EYS44_RS04165	COG1090	epimerase
EYS44_RS04180	COG2814	Major facilitator Superfamily
EYS44_RS04190	COG3591	Belongs to the peptidase S1B family
EYS44_RS04205	COG3103	Sh3 type 3 domain protein
EYS44_RS04210	COG5658	integral membrane protein
EYS44_RS04215	COG0596	Alpha beta hydrolase
EYS44_RS04220	COG0463	Glycosyl transferase, family 2
EYS44_RS04225	COG4485	Bacterial membrane protein, YfhO
EYS44_RS04230	COG1988	membrane-bound metal-dependent
EYS44_RS04235	COG1194	a g-specific adenine glycosylase
EYS44_RS04245	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS04265	COG1132	(ABC) transporter
EYS44_RS04270	COG4129	membrane
EYS44_RS04280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYS44_RS04285	COG0735	belongs to the Fur family
EYS44_RS04400	COG3340	Belongs to the peptidase S51 family
EYS44_RS04410	COG0277	FAD linked oxidase domain protein
EYS44_RS04420	COG0747	negative chemotaxis
EYS44_RS04425	COG0601	transmembrane transport
EYS44_RS04430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYS44_RS04435	COG0444	Belongs to the ABC transporter superfamily
EYS44_RS04440	COG4608	Belongs to the ABC transporter superfamily
EYS44_RS04445	COG0753	catalase activity
EYS44_RS04455	COG1116	anion transmembrane transporter activity
EYS44_RS04460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYS44_RS04465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYS44_RS04485	COG1476	TRANSCRIPTIONal
EYS44_RS04495	COG3382	B3 4 domain protein
EYS44_RS04500	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYS44_RS04510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYS44_RS04515	COG0789	Transcriptional regulator
EYS44_RS04520	COG1664	Polymer-forming cytoskeletal
EYS44_RS04525	COG1664	Polymer-forming cytoskeletal
EYS44_RS04530	COG2766	serine protein kinase
EYS44_RS04545	COG1846	Transcriptional regulator
EYS44_RS04550	COG1566	PFAM secretion protein HlyD family protein
EYS44_RS04555	COG2814	Major facilitator Superfamily
EYS44_RS04560	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYS44_RS04575	COG1725	Transcriptional regulator
EYS44_RS04580	COG1131	(ABC) transporter
EYS44_RS04585	COG1131	(ABC) transporter
EYS44_RS04590	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EYS44_RS04595	COG1278	Cold shock
EYS44_RS04605	COG1464	Belongs to the NlpA lipoprotein family
EYS44_RS04610	COG3706	GGDEF domain
EYS44_RS04615	COG1823	symporter activity
EYS44_RS04635	COG5577	PFAM Coat F domain
EYS44_RS04640	COG0737	Belongs to the 5'-nucleotidase family
EYS44_RS04640	COG1525	nuclease
EYS44_RS04640	COG4085	toxin activity
EYS44_RS04645	COG3764	Sortase (surface protein transpeptidase)
EYS44_RS04650	COG0564	pseudouridine synthase activity
EYS44_RS04660	COG0517	IMP dehydrogenase activity
EYS44_RS04665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYS44_RS04670	COG3153	acetyltransferase
EYS44_RS04670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYS44_RS04675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYS44_RS04680	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EYS44_RS04685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EYS44_RS04695	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EYS44_RS04700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYS44_RS04705	COG4585	Histidine kinase
EYS44_RS04705	COG2203	Gaf domain
EYS44_RS04710	COG2197	response regulator
EYS44_RS04715	COG0431	NADPH-dependent FMN reductase
EYS44_RS04730	COG1388	LysM domain
EYS44_RS04730	COG0791	NLP P60 protein
EYS44_RS04735	COG1959	2 iron, 2 sulfur cluster binding
EYS44_RS04740	COG0668	transmembrane transport
EYS44_RS04745	COG2719	SpoVR family
EYS44_RS04750	COG1785	Belongs to the alkaline phosphatase family
EYS44_RS04755	COG1388	LysM domain
EYS44_RS04755	COG0791	NLP P60 protein
EYS44_RS04760	COG0583	DNA-binding transcription factor activity
EYS44_RS04765	COG0372	Belongs to the citrate synthase family
EYS44_RS04770	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS04775	COG0531	amino acid
EYS44_RS04780	COG0733	neurotransmitter:sodium symporter activity
EYS44_RS04795	COG1595	DNA-templated transcription, initiation
EYS44_RS04800	COG0204	Acyl-transferase
EYS44_RS04805	COG1253	flavin adenine dinucleotide binding
EYS44_RS04810	COG0789	Transcriptional regulator
EYS44_RS04815	COG0436	Aminotransferase
EYS44_RS04820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYS44_RS04825	COG1253	flavin adenine dinucleotide binding
EYS44_RS04830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYS44_RS04835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYS44_RS04840	COG0584	glycerophosphoryl diester phosphodiesterase
EYS44_RS04850	COG0668	transmembrane transport
EYS44_RS04855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYS44_RS04860	COG0726	polysaccharide deacetylase
EYS44_RS04865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYS44_RS04870	COG3226	Transcriptional regulator
EYS44_RS04880	COG0589	response to stress
EYS44_RS04885	COG1132	(ABC) transporter
EYS44_RS04890	COG1132	(ABC) transporter
EYS44_RS04895	COG0702	epimerase
EYS44_RS04915	COG0189	ligase activity
EYS44_RS04920	COG0189	ligase activity
EYS44_RS04935	COG4335	DNA alkylation repair
EYS44_RS04940	COG0561	phosphatase activity
EYS44_RS04945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYS44_RS04955	COG0475	glutathione-regulated potassium exporter activity
EYS44_RS04960	COG0490	domain, Protein
EYS44_RS04970	COG1024	Enoyl-CoA hydratase
EYS44_RS04980	COG4152	abc transporter atp-binding protein
EYS44_RS04985	COG1668	transmembrane transport
EYS44_RS04990	COG0420	3'-5' exonuclease activity
EYS44_RS04995	COG4717	serine-type aminopeptidase activity
EYS44_RS05010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYS44_RS05050	COG4980	gas vesicle protein
EYS44_RS05065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYS44_RS05070	COG0537	adenosine 5'-monophosphoramidase activity
EYS44_RS05075	COG1131	(ABC) transporter
EYS44_RS05080	COG4473	ABC transporter
EYS44_RS05090	COG1473	amidohydrolase
EYS44_RS05095	COG3069	C4-dicarboxylate transmembrane transporter activity
EYS44_RS05100	COG2329	Antibiotic biosynthesis monooxygenase
EYS44_RS05105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYS44_RS05115	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYS44_RS05120	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EYS44_RS05125	COG1309	transcriptional regulator
EYS44_RS05130	COG1511	domain protein
EYS44_RS05135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYS44_RS05145	COG1363	Peptidase, m42
EYS44_RS05150	COG1301	dicarboxylic acid transport
EYS44_RS05160	COG1234	tRNA 3'-trailer cleavage
EYS44_RS05165	COG0095	Lipoate-protein ligase
EYS44_RS05170	COG0702	epimerase
EYS44_RS05175	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS05185	COG0501	Belongs to the peptidase M48B family
EYS44_RS05190	COG1404	Belongs to the peptidase S8 family
EYS44_RS05200	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EYS44_RS05205	COG0406	alpha-ribazole phosphatase activity
EYS44_RS05210	COG0183	Belongs to the thiolase family
EYS44_RS05215	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS05220	COG1268	BioY protein
EYS44_RS05225	COG0840	transmembrane signaling receptor activity
EYS44_RS05230	COG0723	plastoquinol--plastocyanin reductase activity
EYS44_RS05230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYS44_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS05245	COG4903	ComK protein
EYS44_RS05255	COG5646	InterPro IPR014922
EYS44_RS05275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYS44_RS05290	COG0398	Pfam SNARE associated Golgi protein
EYS44_RS05295	COG0681	Belongs to the peptidase S26 family
EYS44_RS05300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYS44_RS05305	COG1846	Transcriptional regulator
EYS44_RS05310	COG3180	Ammonia monooxygenase
EYS44_RS05315	COG2814	Major facilitator Superfamily
EYS44_RS05325	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EYS44_RS05330	COG2323	membrane
EYS44_RS05345	COG0420	3'-5' exonuclease activity
EYS44_RS05350	COG0419	ATPase involved in DNA repair
EYS44_RS05355	COG1403	HNH endonuclease
EYS44_RS05395	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYS44_RS05415	COG0367	asparagine synthase
EYS44_RS05420	COG1562	ergosterol biosynthetic process
EYS44_RS05425	COG0534	Mate efflux family protein
EYS44_RS05430	COG1917	Cupin 2, conserved barrel domain protein
EYS44_RS05430	COG2207	Transcriptional regulator
EYS44_RS05435	COG1609	Transcriptional regulator
EYS44_RS05440	COG0673	inositol 2-dehydrogenase activity
EYS44_RS05445	COG2318	DinB family
EYS44_RS05455	COG1357	PFAM Pentapeptide repeats (8 copies)
EYS44_RS05460	COG2153	protein acetylation
EYS44_RS05465	COG0646	methionine synthase
EYS44_RS05465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYS44_RS05475	COG2996	Protein conserved in bacteria
EYS44_RS05480	COG1744	ABC transporter substrate-binding protein PnrA-like
EYS44_RS05485	COG0840	transmembrane signaling receptor activity
EYS44_RS05495	COG1307	EDD domain protein, DegV family
EYS44_RS05500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYS44_RS05515	COG0561	phosphatase activity
EYS44_RS05520	COG1073	alpha beta
EYS44_RS05525	COG2151	metal-sulfur cluster biosynthetic enzyme
EYS44_RS05535	COG0277	FAD linked oxidase domain protein
EYS44_RS05540	COG2271	Major facilitator Superfamily
EYS44_RS05550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EYS44_RS05560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYS44_RS05565	COG0505	Belongs to the CarA family
EYS44_RS05570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYS44_RS05575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYS44_RS05595	COG2267	carboxylic ester hydrolase activity
EYS44_RS05605	COG1744	ABC transporter substrate-binding protein PnrA-like
EYS44_RS05620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYS44_RS05625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYS44_RS05630	COG5504	Zn-dependent protease
EYS44_RS05635	COG0444	Belongs to the ABC transporter superfamily
EYS44_RS05640	COG4608	Belongs to the ABC transporter superfamily
EYS44_RS05650	COG0601	transmembrane transport
EYS44_RS05655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYS44_RS05665	COG0180	Tryptophanyl-tRNA synthetase
EYS44_RS05670	COG4166	transmembrane transport
EYS44_RS05675	COG0601	transmembrane transport
EYS44_RS05680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYS44_RS05685	COG0444	Belongs to the ABC transporter superfamily
EYS44_RS05690	COG4608	Belongs to the ABC transporter superfamily
EYS44_RS05700	COG0456	acetyltransferase
EYS44_RS05705	COG1393	Belongs to the ArsC family
EYS44_RS05710	COG0861	Integral membrane protein TerC family
EYS44_RS05715	COG4862	establishment of competence for transformation
EYS44_RS05720	COG4469	Competence protein
EYS44_RS05725	COG1164	Oligoendopeptidase f
EYS44_RS05730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EYS44_RS05735	COG2346	COG2346, Truncated hemoglobins
EYS44_RS05740	COG0741	lytic transglycosylase activity
EYS44_RS05745	COG4116	CYTH
EYS44_RS05755	COG2357	RelA SpoT domain protein
EYS44_RS05760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYS44_RS05765	COG0564	pseudouridine synthase activity
EYS44_RS05775	COG0475	glutathione-regulated potassium exporter activity
EYS44_RS05775	COG0569	domain protein
EYS44_RS05780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EYS44_RS05785	COG0352	thiamine-phosphate diphosphorylase activity
EYS44_RS05790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYS44_RS05795	COG2104	thiamine diphosphate biosynthetic process
EYS44_RS05805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYS44_RS05810	COG0351	phosphomethylpyrimidine kinase
EYS44_RS05815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EYS44_RS05870	COG0210	DNA helicase
EYS44_RS05890	COG1131	(ABC) transporter
EYS44_RS05900	COG2153	protein acetylation
EYS44_RS05910	COG2382	esterase
EYS44_RS05915	COG0626	cystathionine gamma-synthase activity
EYS44_RS05920	COG0626	cystathionine gamma-synthase activity
EYS44_RS05940	COG4974	Belongs to the 'phage' integrase family
EYS44_RS06060	COG5444	nuclease activity
EYS44_RS06070	COG0346	lactoylglutathione lyase activity
EYS44_RS06075	COG2367	Beta-lactamase
EYS44_RS06080	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EYS44_RS06090	COG1846	Transcriptional regulator
EYS44_RS06100	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EYS44_RS06105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYS44_RS06110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EYS44_RS06115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYS44_RS06115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYS44_RS06120	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYS44_RS06130	COG1349	DNA-binding transcription factor activity
EYS44_RS06145	COG1285	pathogenesis
EYS44_RS06160	COG2205	protein histidine kinase activity
EYS44_RS06170	COG3383	formate dehydrogenase (NAD+) activity
EYS44_RS06175	COG2427	Protein of unknown function (DUF1641)
EYS44_RS06180	COG2124	cytochrome p450
EYS44_RS06185	COG1819	glycosyl
EYS44_RS06195	COG1587	Uroporphyrinogen-III synthase
EYS44_RS06200	COG0390	transport system, permease component
EYS44_RS06205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYS44_RS06210	COG0697	spore germination
EYS44_RS06215	COG4297	protein containing double-stranded beta helix domain
EYS44_RS06225	COG1252	NADH dehydrogenase
EYS44_RS06235	COG2211	Major facilitator Superfamily
EYS44_RS06240	COG1609	Transcriptional regulator
EYS44_RS06245	COG0246	Mannitol dehydrogenase
EYS44_RS06250	COG2721	sulfolactate sulfo-lyase activity
EYS44_RS06255	COG0745	RESPONSE REGULATOR receiver
EYS44_RS06260	COG2205	protein histidine kinase activity
EYS44_RS06260	COG2770	Histidine kinase
EYS44_RS06280	COG4585	Histidine kinase
EYS44_RS06285	COG2197	response regulator
EYS44_RS06310	COG0730	response to heat
EYS44_RS06315	COG2318	DinB family
EYS44_RS06320	COG0457	Tetratricopeptide repeat
EYS44_RS06330	COG5632	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS06330	COG3409	Peptidoglycan-binding domain 1 protein
EYS44_RS06330	COG1388	LysM domain
EYS44_RS06340	COG4195	phage-related replication protein
EYS44_RS06345	COG2856	Zn peptidase
EYS44_RS06350	COG1396	sequence-specific DNA binding
EYS44_RS06360	COG1522	sequence-specific DNA binding
EYS44_RS06365	COG1484	DNA-dependent DNA replication
EYS44_RS06380	COG1595	DNA-templated transcription, initiation
EYS44_RS06385	COG5484	DNA packaging
EYS44_RS06385	COG3728	DNA packaging
EYS44_RS06390	COG1783	phage Terminase large subunit
EYS44_RS06395	COG5518	Phage portal protein
EYS44_RS06400	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EYS44_RS06405	COG4653	Phage capsid family
EYS44_RS06455	COG3953	SLT domain
EYS44_RS06455	COG3953	SLT domain
EYS44_RS06455	COG3953	SLT domain
EYS44_RS06455	COG5412	phage tail tape measure protein
EYS44_RS06455	COG5412	phage tail tape measure protein
EYS44_RS06455	COG5412	phage tail tape measure protein
EYS44_RS06460	COG1652	LysM domain
EYS44_RS06465	COG4193	domain, Protein
EYS44_RS06475	COG3628	GPW Gp25 family protein
EYS44_RS06480	COG3299	homolog of phage Mu protein gp47
EYS44_RS06485	COG3778	Protein conserved in bacteria
EYS44_RS06525	COG5632	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS06525	COG3409	Peptidoglycan-binding domain 1 protein
EYS44_RS06540	COG0306	phosphate transporter
EYS44_RS06545	COG1392	Phosphate transport regulator
EYS44_RS06550	COG0531	amino acid
EYS44_RS06555	COG0346	lactoylglutathione lyase activity
EYS44_RS06560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYS44_RS06565	COG0463	Glycosyl transferase, family 2
EYS44_RS06570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYS44_RS06575	COG0477	Major facilitator Superfamily
EYS44_RS06580	COG2362	D-Aminopeptidase
EYS44_RS06585	COG0601	transmembrane transport
EYS44_RS06590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYS44_RS06595	COG0444	Belongs to the ABC transporter superfamily
EYS44_RS06600	COG4166	transmembrane transport
EYS44_RS06605	COG1619	proteins homologs of microcin C7 resistance protein MccF
EYS44_RS06610	COG4948	Mandelate Racemase Muconate Lactonizing
EYS44_RS06615	COG0791	NLP P60 protein
EYS44_RS06620	COG4608	Belongs to the ABC transporter superfamily
EYS44_RS06625	COG2706	6-phosphogluconolactonase activity
EYS44_RS06630	COG1834	amidinotransferase
EYS44_RS06635	COG1607	acyl-coa hydrolase
EYS44_RS06640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYS44_RS06645	COG2076	Multidrug Resistance protein
EYS44_RS06650	COG2076	Multidrug Resistance protein
EYS44_RS06655	COG0788	formyltetrahydrofolate deformylase activity
EYS44_RS06660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYS44_RS06670	COG1764	response to oxidative stress
EYS44_RS06675	COG1846	Transcriptional regulator
EYS44_RS06680	COG1764	response to oxidative stress
EYS44_RS06695	COG0457	Tetratricopeptide repeat
EYS44_RS06695	COG0463	Glycosyl transferase, family 2
EYS44_RS06705	COG2814	Major facilitator Superfamily
EYS44_RS06710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYS44_RS06720	COG1404	Belongs to the peptidase S8 family
EYS44_RS06725	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS44_RS06730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EYS44_RS06735	COG1122	ATPase activity
EYS44_RS06740	COG4721	ABC-type cobalt transport system, permease component
EYS44_RS06745	COG3858	chitin binding
EYS44_RS06745	COG1388	LysM domain
EYS44_RS06765	COG2239	Acts as a magnesium transporter
EYS44_RS06770	COG0789	Transcriptional regulator
EYS44_RS06785	COG1846	Transcriptional regulator
EYS44_RS06790	COG0726	polysaccharide deacetylase
EYS44_RS06795	COG1793	dna ligase
EYS44_RS06795	COG3285	dna ligase
EYS44_RS06800	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EYS44_RS06805	COG0586	Pfam SNARE associated Golgi protein
EYS44_RS06810	COG0861	Integral membrane protein TerC family
EYS44_RS06815	COG1191	sigma factor activity
EYS44_RS06840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYS44_RS06845	COG2323	membrane
EYS44_RS06855	COG3594	Acyltransferase
EYS44_RS06860	COG5002	protein histidine kinase activity
EYS44_RS06865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYS44_RS06880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYS44_RS06885	COG0436	Aminotransferase
EYS44_RS06915	COG3852	Histidine kinase
EYS44_RS06920	COG1846	Transcriptional regulator
EYS44_RS06925	COG1360	Flagellar Motor Protein
EYS44_RS06930	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYS44_RS06935	COG0542	response to heat
EYS44_RS06945	COG3949	Membrane
EYS44_RS06960	COG0720	synthase
EYS44_RS06965	COG0602	queuosine metabolic process
EYS44_RS06980	COG4873	Protein conserved in bacteria
EYS44_RS06990	COG3773	Cell wall hydrolase
EYS44_RS06995	COG2244	polysaccharide biosynthetic process
EYS44_RS07000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYS44_RS07005	COG2217	Heavy metal translocating P-type atpase
EYS44_RS07010	COG0006	proline dipeptidase activity
EYS44_RS07015	COG1609	Transcriptional regulator
EYS44_RS07020	COG3711	transcriptional antiterminator
EYS44_RS07025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYS44_RS07025	COG2190	(PTS) system
EYS44_RS07025	COG1263	PTS System
EYS44_RS07030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS44_RS07035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYS44_RS07045	COG1533	DNA photolyase activity
EYS44_RS07050	COG0840	transmembrane signaling receptor activity
EYS44_RS07055	COG2084	Dehydrogenase
EYS44_RS07060	COG2340	Cysteine-rich secretory protein family
EYS44_RS07065	COG0768	penicillin binding
EYS44_RS07070	COG4191	Histidine kinase
EYS44_RS07075	COG0436	Aminotransferase
EYS44_RS07085	COG0835	chemotaxis
EYS44_RS07085	COG0784	Response regulator, receiver
EYS44_RS07095	COG2814	Major facilitator Superfamily
EYS44_RS07100	COG1376	ErfK ybiS ycfS ynhG family protein
EYS44_RS07105	COG1408	metallophosphoesterase
EYS44_RS07110	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS07125	COG2200	EAL domain
EYS44_RS07130	COG4703	Protein of unknown function (DUF1797)
EYS44_RS07135	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EYS44_RS07145	COG0517	IMP dehydrogenase activity
EYS44_RS07150	COG0583	DNA-binding transcription factor activity
EYS44_RS07155	COG0716	FMN binding
EYS44_RS07165	COG0716	FMN binding
EYS44_RS07185	COG0668	transmembrane transport
EYS44_RS07190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYS44_RS07210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYS44_RS07215	COG0303	'Molybdopterin
EYS44_RS07220	COG1763	Mo-molybdopterin cofactor biosynthetic process
EYS44_RS07225	COG0314	molybdopterin synthase activity
EYS44_RS07230	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EYS44_RS07240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYS44_RS07245	COG1136	(ABC) transporter
EYS44_RS07250	COG0577	efflux transmembrane transporter activity
EYS44_RS07255	COG1349	DNA-binding transcription factor activity
EYS44_RS07260	COG1105	Belongs to the carbohydrate kinase PfkB family
EYS44_RS07265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYS44_RS07265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYS44_RS07265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS44_RS07270	COG0681	Belongs to the peptidase S26 family
EYS44_RS07280	COG0488	(ABC) transporter
EYS44_RS07285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EYS44_RS07290	COG2309	aminopeptidase activity
EYS44_RS07300	COG1077	Cell shape determining protein MreB Mrl
EYS44_RS07310	COG2002	toxin-antitoxin pair type II binding
EYS44_RS07315	COG3852	Histidine kinase
EYS44_RS07320	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EYS44_RS07320	COG2105	PFAM AIG2 family protein
EYS44_RS07325	COG0569	domain protein
EYS44_RS07335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EYS44_RS07350	COG0561	phosphatase activity
EYS44_RS07355	COG0242	peptide deformylase activity
EYS44_RS07365	COG0497	DNA recombination
EYS44_RS07380	COG4221	oxidoreductase activity
EYS44_RS07380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS07380	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS07380	COG3321	synthase
EYS44_RS07385	COG4221	oxidoreductase activity
EYS44_RS07385	COG3321	synthase
EYS44_RS07385	COG0300	oxidoreductase activity
EYS44_RS07385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS07390	COG4221	oxidoreductase activity
EYS44_RS07390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS07390	COG3321	synthase
EYS44_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS07395	COG0300	oxidoreductase activity
EYS44_RS07395	COG4221	oxidoreductase activity
EYS44_RS07395	COG3321	synthase
EYS44_RS07395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS07400	COG3321	synthase
EYS44_RS07400	COG0300	oxidoreductase activity
EYS44_RS07400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS07400	COG4221	oxidoreductase activity
EYS44_RS07405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS07405	COG0300	oxidoreductase activity
EYS44_RS07405	COG3321	synthase
EYS44_RS07405	COG4221	oxidoreductase activity
EYS44_RS07410	COG4221	oxidoreductase activity
EYS44_RS07410	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS07410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS07410	COG3321	synthase
EYS44_RS07415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYS44_RS07420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYS44_RS07425	COG0022	dehydrogenase e1 component
EYS44_RS07430	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYS44_RS07435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYS44_RS07440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYS44_RS07455	COG1982	Orn Lys Arg decarboxylase major
EYS44_RS07485	COG0483	inositol monophosphate 1-phosphatase activity
EYS44_RS07495	COG3227	Zinc metalloprotease (Elastase)
EYS44_RS07510	COG1595	DNA-templated transcription, initiation
EYS44_RS07530	COG1217	gtp-binding protein TYPA
EYS44_RS07540	COG4896	Protein conserved in bacteria
EYS44_RS07550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYS44_RS07555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYS44_RS07560	COG2066	Belongs to the glutaminase family
EYS44_RS07570	COG0772	Belongs to the SEDS family
EYS44_RS07575	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EYS44_RS07590	COG2010	Cytochrome c
EYS44_RS07590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYS44_RS07595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYS44_RS07600	COG1845	cytochrome c oxidase, subunit III
EYS44_RS07605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYS44_RS07610	COG3336	cytochrome c oxidase
EYS44_RS07620	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EYS44_RS07625	COG2340	Cysteine-rich secretory protein family
EYS44_RS07640	COG3679	Belongs to the UPF0342 family
EYS44_RS07655	COG0742	ribosomal rna small subunit methyltransferase
EYS44_RS07665	COG3314	Sporulation integral membrane protein YlbJ
EYS44_RS07670	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYS44_RS07675	COG3480	Lon protease (S16) C-terminal proteolytic domain
EYS44_RS07685	COG1399	metal-binding, possibly nucleic acid-binding protein
EYS44_RS07705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EYS44_RS07725	COG4839	cell division protein FtsL
EYS44_RS07730	COG0768	penicillin binding
EYS44_RS07735	COG0768	penicillin binding
EYS44_RS07755	COG0772	Belongs to the SEDS family
EYS44_RS07770	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYS44_RS07775	COG0849	cell division
EYS44_RS07780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EYS44_RS07785	COG4412	M6 family metalloprotease domain protein
EYS44_RS07785	COG1404	Belongs to the peptidase S8 family
EYS44_RS07795	COG1191	sigma factor activity
EYS44_RS07800	COG1191	sigma factor activity
EYS44_RS07805	COG1119	ATPase activity
EYS44_RS07810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYS44_RS07815	COG1873	PFAM PRC-barrel domain
EYS44_RS07820	COG1496	oxidoreductase activity
EYS44_RS07825	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYS44_RS07835	COG0762	integral membrane protein
EYS44_RS07840	COG2302	S4 RNA-binding domain
EYS44_RS07845	COG3599	regulation of cell shape
EYS44_RS07855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYS44_RS07860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYS44_RS07870	COG0564	pseudouridine synthase activity
EYS44_RS07880	COG2233	PERMEase
EYS44_RS07890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYS44_RS07895	COG0505	Belongs to the CarA family
EYS44_RS07900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYS44_RS07915	COG0284	orotidine-5'-phosphate decarboxylase activity
EYS44_RS07920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EYS44_RS07930	COG0306	phosphate transporter
EYS44_RS07945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYS44_RS07950	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EYS44_RS07955	COG1648	precorrin-2 dehydrogenase activity
EYS44_RS07970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYS44_RS07975	COG1561	YicC-like family, N-terminal region
EYS44_RS07985	COG0194	GDP metabolic process
EYS44_RS07995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYS44_RS08000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYS44_RS08005	COG0242	peptide deformylase activity
EYS44_RS08015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYS44_RS08015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYS44_RS08025	COG0631	protein serine/threonine phosphatase activity
EYS44_RS08030	COG2815	serine threonine protein kinase
EYS44_RS08030	COG0515	serine threonine protein kinase
EYS44_RS08040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYS44_RS08045	COG1564	THIamine pyrophosphokinase
EYS44_RS08060	COG1302	Protein conserved in bacteria
EYS44_RS08065	COG1461	Dihydroxyacetone kinase
EYS44_RS08070	COG1760	l-serine dehydratase
EYS44_RS08075	COG1760	l-serine dehydratase
EYS44_RS08080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYS44_RS08095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYS44_RS08100	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS08115	COG1196	nuclear chromosome segregation
EYS44_RS08120	COG0552	protein localization to endoplasmic reticulum
EYS44_RS08135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYS44_RS08145	COG1837	Belongs to the UPF0109 family
EYS44_RS08170	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EYS44_RS08185	COG2257	FlhB HrpN YscU SpaS Family
EYS44_RS08195	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYS44_RS08200	COG0758	DNA mediated transformation
EYS44_RS08205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYS44_RS08215	COG4974	Belongs to the 'phage' integrase family
EYS44_RS08235	COG1815	bacterial-type flagellum-dependent cell motility
EYS44_RS08240	COG1558	bacterial-type flagellum-dependent cell motility
EYS44_RS08245	COG1677	Flagellar hook-basal body complex protein FliE
EYS44_RS08250	COG1766	The M ring may be actively involved in energy transduction
EYS44_RS08255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYS44_RS08260	COG1317	bacterial-type flagellum organization
EYS44_RS08265	COG1157	protein secretion by the type III secretion system
EYS44_RS08270	COG2882	bacterial-type flagellum organization
EYS44_RS08275	COG3334	PFAM MgtE intracellular
EYS44_RS08280	COG3144	bacterial-type flagellum assembly
EYS44_RS08285	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYS44_RS08290	COG4786	Flagellar basal body rod
EYS44_RS08295	COG1582	Flagellar protein (FlbD)
EYS44_RS08300	COG1580	Controls the rotational direction of flagella during chemotaxis
EYS44_RS08305	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYS44_RS08310	COG1776	CheC inhibitor of MCP methylation
EYS44_RS08310	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYS44_RS08315	COG2201	protein-glutamate methylesterase activity
EYS44_RS08320	COG3190	flagellar
EYS44_RS08325	COG1338	Plays a role in the flagellum-specific transport system
EYS44_RS08330	COG1987	bacterial-type flagellum assembly
EYS44_RS08335	COG1684	flagellar biosynthetic protein fliR
EYS44_RS08340	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYS44_RS08345	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYS44_RS08350	COG1419	protein localization to endoplasmic reticulum
EYS44_RS08355	COG0455	bacterial-type flagellum organization
EYS44_RS08360	COG2201	protein-glutamate methylesterase activity
EYS44_RS08365	COG0643	Histidine kinase
EYS44_RS08365	COG2198	Histidine kinase
EYS44_RS08370	COG0835	chemotaxis
EYS44_RS08375	COG1776	CheC inhibitor of MCP methylation
EYS44_RS08385	COG1191	sigma factor activity
EYS44_RS08415	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EYS44_RS08420	COG4589	Belongs to the CDS family
EYS44_RS08430	COG0750	zinc metalloprotease
EYS44_RS08440	COG2176	DNA-directed DNA polymerase activity
EYS44_RS08450	COG0195	Participates in both transcription termination and antitermination
EYS44_RS08455	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EYS44_RS08460	COG1358	cellular component organization or biogenesis
EYS44_RS08470	COG1550	Protein conserved in bacteria
EYS44_RS08485	COG0196	riboflavin kinase activity
EYS44_RS08500	COG0726	polysaccharide deacetylase
EYS44_RS08505	COG0612	Peptidase, M16
EYS44_RS08510	COG1873	PFAM PRC-barrel domain
EYS44_RS08515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYS44_RS08520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYS44_RS08525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYS44_RS08530	COG0527	aspartate kinase activity
EYS44_RS08540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EYS44_RS08545	COG0740	serine-type endopeptidase activity
EYS44_RS08555	COG4980	gas vesicle protein
EYS44_RS08555	COG1674	ftsk spoiiie
EYS44_RS08560	COG2188	Transcriptional regulator
EYS44_RS08565	COG2814	Major facilitator Superfamily
EYS44_RS08570	COG1846	Transcriptional regulator
EYS44_RS08575	COG2409	Drug exporters of the RND superfamily
EYS44_RS08575	COG1033	growth of symbiont in host cell
EYS44_RS08580	COG0612	Peptidase, M16
EYS44_RS08585	COG0612	Peptidase, M16
EYS44_RS08590	COG0300	oxidoreductase activity
EYS44_RS08605	COG1426	Protein conserved in bacteria
EYS44_RS08610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EYS44_RS08625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYS44_RS08635	COG1692	metallophosphoesterase
EYS44_RS08640	COG2359	stage V sporulation protein S
EYS44_RS08660	COG4550	Control of competence regulator ComK, YlbF/YmcA
EYS44_RS08730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS08735	COG3425	synthase
EYS44_RS08740	COG1024	Enoyl-CoA hydratase
EYS44_RS08745	COG1024	Enoyl-CoA hydratase
EYS44_RS08750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS08750	COG3321	synthase
EYS44_RS08750	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS08750	COG0300	oxidoreductase activity
EYS44_RS08755	COG0300	oxidoreductase activity
EYS44_RS08755	COG3321	synthase
EYS44_RS08755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS08755	COG4221	oxidoreductase activity
EYS44_RS08760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYS44_RS08760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS08760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYS44_RS08760	COG3321	synthase
EYS44_RS08760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS08760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS08760	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS08760	COG3321	synthase
EYS44_RS08760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS08760	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS08765	COG4221	oxidoreductase activity
EYS44_RS08765	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS08765	COG3321	synthase
EYS44_RS08765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS08770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYS44_RS08770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS08770	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EYS44_RS08770	COG3321	synthase
EYS44_RS08775	COG2124	cytochrome p450
EYS44_RS08780	COG3209	COG3209 Rhs family protein
EYS44_RS08785	COG3619	membrane
EYS44_RS08795	COG1404	Belongs to the peptidase S8 family
EYS44_RS08805	COG4195	phage-related replication protein
EYS44_RS08810	COG1764	response to oxidative stress
EYS44_RS08820	COG2076	Multidrug Resistance protein
EYS44_RS08860	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYS44_RS08865	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYS44_RS08875	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS08885	COG0464	growth
EYS44_RS08890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYS44_RS08895	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EYS44_RS08900	COG0789	Transcriptional regulator
EYS44_RS08905	COG0174	glutamine synthetase
EYS44_RS08915	COG2211	Major facilitator Superfamily
EYS44_RS08920	COG3507	Belongs to the glycosyl hydrolase 43 family
EYS44_RS08935	COG1070	Carbohydrate kinase
EYS44_RS08940	COG0574	Belongs to the PEP-utilizing enzyme family
EYS44_RS08940	COG3848	Pyruvate phosphate dikinase
EYS44_RS08965	COG1064	alcohol dehydrogenase
EYS44_RS09005	COG3397	chitin binding
EYS44_RS09025	COG5434	Belongs to the glycosyl hydrolase 28 family
EYS44_RS09030	COG0756	dUTP diphosphatase activity
EYS44_RS09035	COG4195	phage-related replication protein
EYS44_RS09065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYS44_RS09075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYS44_RS09095	COG0785	Cytochrome C biogenesis protein
EYS44_RS09100	COG2201	protein-glutamate methylesterase activity
EYS44_RS09105	COG4846	Membrane protein involved in cytochrome C biogenesis
EYS44_RS09115	COG0071	Belongs to the small heat shock protein (HSP20) family
EYS44_RS09130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYS44_RS09135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYS44_RS09155	COG0824	Thioesterase
EYS44_RS09165	COG4841	protein insertion into membrane
EYS44_RS09175	COG1832	CoA-binding protein
EYS44_RS09180	COG0187	DNA topoisomerase II activity
EYS44_RS09185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYS44_RS09195	COG1115	amino acid carrier protein
EYS44_RS09205	COG1063	alcohol dehydrogenase
EYS44_RS09210	COG0800	Aldolase
EYS44_RS09215	COG1312	Catalyzes the dehydration of D-mannonate
EYS44_RS09220	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS09225	COG1609	Transcriptional regulator
EYS44_RS09265	COG2205	protein histidine kinase activity
EYS44_RS09270	COG0745	RESPONSE REGULATOR receiver
EYS44_RS09280	COG3507	Belongs to the glycosyl hydrolase 43 family
EYS44_RS09310	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS09315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYS44_RS09320	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EYS44_RS09325	COG2610	gluconate transmembrane transporter activity
EYS44_RS09330	COG2124	cytochrome p450
EYS44_RS09350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYS44_RS09360	COG2246	polysaccharide biosynthetic process
EYS44_RS09365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYS44_RS09370	COG0586	Pfam SNARE associated Golgi protein
EYS44_RS09375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYS44_RS09380	COG1024	Enoyl-CoA hydratase
EYS44_RS09385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYS44_RS09390	COG0511	ligase activity, forming carbon-carbon bonds
EYS44_RS09395	COG0439	Biotin carboxylase
EYS44_RS09400	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS09405	COG1960	acyl-CoA dehydrogenase activity
EYS44_RS09410	COG1649	PFAM Uncharacterised BCR, COG1649
EYS44_RS09420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS09420	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EYS44_RS09425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS09430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS09435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS09440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS09450	COG2027	D-alanyl-D-alanine carboxypeptidase
EYS44_RS09455	COG2017	converts alpha-aldose to the beta-anomer
EYS44_RS09460	COG0534	Mate efflux family protein
EYS44_RS09475	COG0582	viral genome integration into host DNA
EYS44_RS09480	COG0166	Belongs to the GPI family
EYS44_RS09485	COG0405	Gamma-glutamyltransferase
EYS44_RS09490	COG2814	Major facilitator Superfamily
EYS44_RS09495	COG0640	Transcriptional regulator
EYS44_RS09510	COG0604	alcohol dehydrogenase
EYS44_RS09515	COG0493	'glutamate synthase
EYS44_RS09520	COG0069	glutamate synthase activity
EYS44_RS09520	COG0070	glutamate synthase
EYS44_RS09520	COG0067	glutamate synthase
EYS44_RS09525	COG0583	DNA-binding transcription factor activity
EYS44_RS09530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYS44_RS09545	COG0300	oxidoreductase activity
EYS44_RS09550	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EYS44_RS09560	COG2814	Major facilitator Superfamily
EYS44_RS09565	COG1070	Carbohydrate kinase
EYS44_RS09570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYS44_RS09575	COG0243	molybdopterin cofactor binding
EYS44_RS09600	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS09605	COG1733	regulation of RNA biosynthetic process
EYS44_RS09610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS44_RS09615	COG2207	Transcriptional regulator
EYS44_RS09615	COG0662	Cupin 2, conserved barrel domain protein
EYS44_RS09620	COG1309	transcriptional regulator
EYS44_RS09625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYS44_RS09635	COG0640	Transcriptional regulator
EYS44_RS09640	COG0741	lytic transglycosylase activity
EYS44_RS09645	COG2322	membrane
EYS44_RS09660	COG1619	proteins homologs of microcin C7 resistance protein MccF
EYS44_RS09670	COG3584	3D domain protein
EYS44_RS09670	COG1388	LysM domain
EYS44_RS09675	COG0514	ATP-dependent DNA helicase (RecQ)
EYS44_RS09685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EYS44_RS09690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYS44_RS09705	COG0071	Belongs to the small heat shock protein (HSP20) family
EYS44_RS09735	COG1012	belongs to the aldehyde dehydrogenase family
EYS44_RS09740	COG1657	PFAM Prenyltransferase squalene oxidase
EYS44_RS09745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYS44_RS09750	COG0733	neurotransmitter:sodium symporter activity
EYS44_RS09755	COG0385	Bile acid
EYS44_RS09760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYS44_RS09765	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYS44_RS09775	COG4548	von Willebrand factor, type A
EYS44_RS09780	COG0714	Associated with various cellular activities
EYS44_RS09785	COG2032	superoxide dismutase activity
EYS44_RS09790	COG1388	LysM domain
EYS44_RS09790	COG0791	NLP P60 protein
EYS44_RS09795	COG1819	glycosyl
EYS44_RS09800	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EYS44_RS09805	COG0534	Mate efflux family protein
EYS44_RS09810	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS44_RS09815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYS44_RS09820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYS44_RS09830	COG2962	Rard protein
EYS44_RS09845	COG1942	4-Oxalocrotonate Tautomerase
EYS44_RS09855	COG1733	regulation of RNA biosynthetic process
EYS44_RS09860	COG0778	Nitroreductase
EYS44_RS09865	COG0400	carboxylic ester hydrolase activity
EYS44_RS09870	COG0346	lactoylglutathione lyase activity
EYS44_RS09880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYS44_RS09890	COG2723	6-phospho-beta-galactosidase activity
EYS44_RS09895	COG2188	Transcriptional regulator
EYS44_RS09900	COG0793	Belongs to the peptidase S41A family
EYS44_RS09900	COG3409	Peptidoglycan-binding domain 1 protein
EYS44_RS09905	COG2226	methyltransferase
EYS44_RS09915	COG1876	peptidase activity
EYS44_RS09935	COG0671	phosphoesterase, PA-phosphatase related
EYS44_RS09970	COG1509	lysine 2,3-aminomutase activity
EYS44_RS09975	COG0456	acetyltransferase
EYS44_RS09980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYS44_RS09985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYS44_RS09990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EYS44_RS09995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYS44_RS10000	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EYS44_RS10010	COG0456	acetyltransferase
EYS44_RS10015	COG0463	Glycosyl transferase, family 2
EYS44_RS10030	COG4641	Protein conserved in bacteria
EYS44_RS10040	COG1086	Polysaccharide biosynthesis protein
EYS44_RS10090	COG1388	LysM domain
EYS44_RS10095	COG0457	Tetratricopeptide repeat
EYS44_RS10145	COG5444	nuclease activity
EYS44_RS10160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYS44_RS10180	COG1846	Transcriptional regulator
EYS44_RS10185	COG4698	Protein conserved in bacteria
EYS44_RS10190	COG2755	lipolytic protein G-D-S-L family
EYS44_RS10195	COG1999	signal sequence binding
EYS44_RS10205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYS44_RS10210	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EYS44_RS10215	COG1272	protein, Hemolysin III
EYS44_RS10220	COG0204	Acyl-transferase
EYS44_RS10225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EYS44_RS10240	COG2521	methyltransferase
EYS44_RS10240	COG2136	Putative SAM-dependent methyltransferase
EYS44_RS10255	COG1413	lyase activity
EYS44_RS10260	COG1418	mRNA catabolic process
EYS44_RS10265	COG0386	Belongs to the glutathione peroxidase family
EYS44_RS10275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYS44_RS10285	COG1278	Cold shock
EYS44_RS10305	COG0328	RNA-DNA hybrid ribonuclease activity
EYS44_RS10310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYS44_RS10315	COG0328	RNA-DNA hybrid ribonuclease activity
EYS44_RS10325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYS44_RS10340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EYS44_RS10350	COG1755	Isoprenylcysteine carboxyl methyltransferase
EYS44_RS10355	COG3424	synthase
EYS44_RS10380	COG1335	isochorismatase
EYS44_RS10405	COG0438	transferase activity, transferring glycosyl groups
EYS44_RS10410	COG5632	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS10415	COG4824	toxin secretion phage lysis holin
EYS44_RS10440	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYS44_RS10450	COG5280	Phage tail tape measure protein TP901
EYS44_RS10450	COG3953	SLT domain
EYS44_RS10550	COG1595	DNA-templated transcription, initiation
EYS44_RS10580	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EYS44_RS10585	COG1484	DNA-dependent DNA replication
EYS44_RS10590	COG3935	DnaD domain protein
EYS44_RS10630	COG3645	SOS response
EYS44_RS10630	COG3646	Phage regulatory protein
EYS44_RS10645	COG3620	sequence-specific DNA binding
EYS44_RS10650	COG0582	viral genome integration into host DNA
EYS44_RS10655	COG2233	PERMEase
EYS44_RS10665	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EYS44_RS10670	COG1199	ATP-dependent helicase activity
EYS44_RS10685	COG0116	Belongs to the methyltransferase superfamily
EYS44_RS10715	COG3359	exonuclease
EYS44_RS10720	COG1111	helicase
EYS44_RS10720	COG1205	dead DEAH box helicase
EYS44_RS10725	COG2190	(PTS) system
EYS44_RS10730	COG0071	Belongs to the small heat shock protein (HSP20) family
EYS44_RS10770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYS44_RS10770	COG4499	WXG100 protein secretion system (Wss), protein YukC
EYS44_RS10780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYS44_RS10785	COG3935	DnaD domain protein
EYS44_RS10795	COG0436	Aminotransferase
EYS44_RS10800	COG5353	protein conserved in bacteria
EYS44_RS10810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYS44_RS10810	COG1199	ATP-dependent helicase activity
EYS44_RS10840	COG0438	transferase activity, transferring glycosyl groups
EYS44_RS10845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYS44_RS10860	COG1694	Mazg nucleotide pyrophosphohydrolase
EYS44_RS10865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYS44_RS10870	COG2140	Oxalate decarboxylase
EYS44_RS10880	COG4347	Protein of unknown function (DUF1405)
EYS44_RS10885	COG2010	Cytochrome c
EYS44_RS10885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYS44_RS10890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYS44_RS10895	COG0723	plastoquinol--plastocyanin reductase activity
EYS44_RS10910	COG0457	Tetratricopeptide repeat
EYS44_RS10920	COG0287	Prephenate dehydrogenase
EYS44_RS10955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYS44_RS10960	COG4401	Chorismate mutase type I
EYS44_RS10975	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYS44_RS10980	COG0105	UTP biosynthetic process
EYS44_RS10985	COG0142	geranyltranstransferase activity
EYS44_RS10995	COG0142	geranyltranstransferase activity
EYS44_RS11010	COG0776	regulation of translation
EYS44_RS11015	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EYS44_RS11055	COG0539	negative regulation of cytoplasmic translation
EYS44_RS11065	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EYS44_RS11070	COG2959	enzyme of heme biosynthesis
EYS44_RS11075	COG3773	Cell wall hydrolase
EYS44_RS11075	COG3409	Peptidoglycan-binding domain 1 protein
EYS44_RS11080	COG2339	peptidase activity
EYS44_RS11085	COG0492	ferredoxin-NADP+ reductase activity
EYS44_RS11090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYS44_RS11095	COG4862	establishment of competence for transformation
EYS44_RS11100	COG1408	metallophosphoesterase
EYS44_RS11110	COG1388	LysM domain
EYS44_RS11115	COG1266	CAAX protease self-immunity
EYS44_RS11120	COG0514	ATP-dependent DNA helicase (RecQ)
EYS44_RS11125	COG4955	Helix-turn-helix domain
EYS44_RS11130	COG1141	Ferredoxin
EYS44_RS11135	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EYS44_RS11140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYS44_RS11150	COG1595	DNA-templated transcription, initiation
EYS44_RS11155	COG5002	protein histidine kinase activity
EYS44_RS11160	COG0745	RESPONSE REGULATOR receiver
EYS44_RS11165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYS44_RS11170	COG1333	cytochrome c biogenesis protein
EYS44_RS11175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYS44_RS11180	COG1187	pseudouridine synthase activity
EYS44_RS11185	COG0700	Nucleoside recognition
EYS44_RS11190	COG2715	membrane protein required for spore maturation
EYS44_RS11195	COG1686	Belongs to the peptidase S11 family
EYS44_RS11220	COG1547	Domain of unknown function (DUF309)
EYS44_RS11230	COG0456	acetyltransferase
EYS44_RS11245	COG0307	riboflavin synthase, alpha
EYS44_RS11250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYS44_RS11250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYS44_RS11260	COG0681	Belongs to the peptidase S26 family
EYS44_RS11270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYS44_RS11275	COG4086	secreted protein
EYS44_RS11280	COG0019	diaminopimelate decarboxylase activity
EYS44_RS11285	COG0697	spore germination
EYS44_RS11300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYS44_RS11320	COG1191	sigma factor activity
EYS44_RS11330	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS44_RS11335	COG1686	Belongs to the peptidase S11 family
EYS44_RS11340	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EYS44_RS11345	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EYS44_RS11350	COG4974	Belongs to the 'phage' integrase family
EYS44_RS11360	COG0735	belongs to the Fur family
EYS44_RS11365	COG1300	Membrane
EYS44_RS11380	COG0281	malic enzyme
EYS44_RS11385	COG1757	Na H antiporter
EYS44_RS11390	COG1027	Aspartate ammonia-lyase
EYS44_RS11395	COG0252	asparaginase activity
EYS44_RS11400	COG1396	sequence-specific DNA binding
EYS44_RS11405	COG1379	DNA repair
EYS44_RS11410	COG0494	nUDIX hydrolase
EYS44_RS11420	COG0667	Aldo Keto reductase
EYS44_RS11430	COG1073	alpha beta
EYS44_RS11440	COG4918	Iron-sulphur cluster biosynthesis
EYS44_RS11445	COG0456	acetyltransferase
EYS44_RS11445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EYS44_RS11450	COG2329	Antibiotic biosynthesis monooxygenase
EYS44_RS11455	COG0456	acetyltransferase
EYS44_RS11460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYS44_RS11475	COG0628	permease
EYS44_RS11485	COG0346	lactoylglutathione lyase activity
EYS44_RS11495	COG3048	D-serine ammonia-lyase activity
EYS44_RS11500	COG0300	oxidoreductase activity
EYS44_RS11505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYS44_RS11510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EYS44_RS11515	COG1024	Enoyl-CoA hydratase
EYS44_RS11520	COG3425	synthase
EYS44_RS11525	COG2124	cytochrome p450
EYS44_RS11530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS11530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYS44_RS11530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS11530	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS11530	COG3321	synthase
EYS44_RS11535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS11535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYS44_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS11535	COG3321	synthase
EYS44_RS11535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS11540	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS11540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS11540	COG0300	oxidoreductase activity
EYS44_RS11540	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS11540	COG3321	synthase
EYS44_RS11545	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS11545	COG3321	synthase
EYS44_RS11545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS11545	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS11545	COG0300	oxidoreductase activity
EYS44_RS11550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYS44_RS11550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS11550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS11550	COG3321	synthase
EYS44_RS11550	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS11555	COG3321	synthase
EYS44_RS11555	COG0300	oxidoreductase activity
EYS44_RS11555	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS11555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS11555	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS11560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS44_RS11560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS11560	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS11560	COG3321	synthase
EYS44_RS11560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYS44_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS11570	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS11585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYS44_RS11585	COG2070	2-Nitropropane dioxygenase
EYS44_RS11595	COG0250	Participates in transcription elongation, termination and antitermination
EYS44_RS11620	COG0596	Alpha beta hydrolase
EYS44_RS11635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYS44_RS11640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EYS44_RS11655	COG0706	membrane insertase activity
EYS44_RS11660	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYS44_RS11665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYS44_RS11670	COG0346	lactoylglutathione lyase activity
EYS44_RS11675	COG1376	ErfK ybiS ycfS ynhG family protein
EYS44_RS11680	COG4129	membrane
EYS44_RS11685	COG1126	abc transporter atp-binding protein
EYS44_RS11690	COG0765	amino acid transport
EYS44_RS11695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYS44_RS11705	COG1597	lipid kinase activity
EYS44_RS11710	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYS44_RS11715	COG0022	dehydrogenase e1 component
EYS44_RS11720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYS44_RS11725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYS44_RS11730	COG3426	butyrate kinase activity
EYS44_RS11735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYS44_RS11740	COG0280	phosphate acetyltransferase
EYS44_RS11745	COG3290	protein histidine kinase activity
EYS44_RS11745	COG3829	transcription factor binding
EYS44_RS11755	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EYS44_RS11760	COG2079	MmgE PrpD family protein
EYS44_RS11765	COG0372	Belongs to the citrate synthase family
EYS44_RS11770	COG1960	acyl-CoA dehydrogenase activity
EYS44_RS11775	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYS44_RS11780	COG0183	Belongs to the thiolase family
EYS44_RS11785	COG0584	glycerophosphoryl diester phosphodiesterase
EYS44_RS11790	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS11810	COG1902	pentaerythritol trinitrate reductase activity
EYS44_RS11825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYS44_RS11830	COG0745	RESPONSE REGULATOR receiver
EYS44_RS11835	COG0750	zinc metalloprotease
EYS44_RS11840	COG0497	DNA recombination
EYS44_RS11850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EYS44_RS11860	COG0142	geranyltranstransferase activity
EYS44_RS11870	COG1570	exodeoxyribonuclease VII activity
EYS44_RS11885	COG1302	Protein conserved in bacteria
EYS44_RS11890	COG0439	Biotin carboxylase
EYS44_RS11895	COG0511	ligase activity, forming carbon-carbon bonds
EYS44_RS11935	COG3854	ATPases associated with a variety of cellular activities
EYS44_RS11950	COG0006	proline dipeptidase activity
EYS44_RS11960	COG3872	metal-dependent enzyme
EYS44_RS11970	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYS44_RS11985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYS44_RS12005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYS44_RS12020	COG1396	sequence-specific DNA binding
EYS44_RS12030	COG0681	Belongs to the peptidase S26 family
EYS44_RS12055	COG4940	Competence protein ComGF
EYS44_RS12065	COG4970	Tfp pilus assembly protein FimT
EYS44_RS12070	COG4537	Required for transformation and DNA binding
EYS44_RS12075	COG1459	type II secretion system
EYS44_RS12080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYS44_RS12085	COG0598	Magnesium transport protein CorA
EYS44_RS12090	COG1253	flavin adenine dinucleotide binding
EYS44_RS12095	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS44_RS12105	COG1393	Belongs to the ArsC family
EYS44_RS12115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYS44_RS12125	COG0011	TIGRFAM Protein of
EYS44_RS12135	COG2866	Carboxypeptidase
EYS44_RS12140	COG1940	carbohydrate kinase activity
EYS44_RS12145	COG4483	Protein conserved in bacteria
EYS44_RS12150	COG1757	Na H antiporter
EYS44_RS12160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYS44_RS12175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYS44_RS12180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYS44_RS12185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYS44_RS12190	COG0581	inorganic phosphate transmembrane transporter activity
EYS44_RS12195	COG0573	inorganic phosphate transmembrane transporter activity
EYS44_RS12200	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYS44_RS12205	COG0768	penicillin binding
EYS44_RS12210	COG0477	Major facilitator Superfamily
EYS44_RS12215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYS44_RS12220	COG2839	Protein conserved in bacteria
EYS44_RS12225	COG5521	maltodextrose utilization protein MalA
EYS44_RS12230	COG1388	LysM domain
EYS44_RS12240	COG4709	membrane
EYS44_RS12245	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EYS44_RS12250	COG0735	belongs to the Fur family
EYS44_RS12255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYS44_RS12270	COG0513	Belongs to the DEAD box helicase family
EYS44_RS12285	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EYS44_RS12290	COG2384	SAM-dependent methyltransferase
EYS44_RS12295	COG2010	Cytochrome c
EYS44_RS12300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYS44_RS12305	COG0358	DNA primase activity
EYS44_RS12320	COG0517	IMP dehydrogenase activity
EYS44_RS12325	COG0751	glycine-tRNA ligase activity
EYS44_RS12345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYS44_RS12350	COG0295	cytidine deaminase activity
EYS44_RS12355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYS44_RS12365	COG1480	7TM receptor with intracellular HD hydrolase
EYS44_RS12370	COG1702	phosphate starvation-inducible protein PhoH
EYS44_RS12375	COG0561	phosphatase activity
EYS44_RS12390	COG4864	UPF0365 protein
EYS44_RS12395	COG1030	water channel activity
EYS44_RS12400	COG1610	YqeY-like protein
EYS44_RS12410	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYS44_RS12415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYS44_RS12420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYS44_RS12450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYS44_RS12465	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS12480	COG1466	dna polymerase III delta subunit
EYS44_RS12495	COG0658	competence protein
EYS44_RS12495	COG2333	competence protein COMEC
EYS44_RS12500	COG2131	deaminase
EYS44_RS12505	COG1596	polysaccharide export
EYS44_RS12505	COG1555	photosystem II stabilization
EYS44_RS12510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EYS44_RS12515	COG2226	methyltransferase
EYS44_RS12520	COG0799	negative regulation of ribosome biogenesis
EYS44_RS12525	COG1713	HD superfamily hydrolase involved in NAD metabolism
EYS44_RS12535	COG1534	Rna-binding protein
EYS44_RS12540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYS44_RS12545	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EYS44_RS12550	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EYS44_RS12560	COG2755	lipolytic protein G-D-S-L family
EYS44_RS12570	COG0398	Pfam SNARE associated Golgi protein
EYS44_RS12600	COG2207	Transcriptional regulator
EYS44_RS12600	COG3708	Transcriptional regulator
EYS44_RS12610	COG0563	adenylate kinase activity
EYS44_RS12620	COG2814	Major facilitator Superfamily
EYS44_RS12630	COG0456	acetyltransferase
EYS44_RS12635	COG2318	DinB family
EYS44_RS12645	COG0561	phosphatase activity
EYS44_RS12650	COG0561	phosphatase activity
EYS44_RS12660	COG1482	cell wall glycoprotein biosynthetic process
EYS44_RS12665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYS44_RS12665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYS44_RS12665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS44_RS12670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS44_RS12670	COG3711	transcriptional antiterminator
EYS44_RS12680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYS44_RS12685	COG0583	DNA-binding transcription factor activity
EYS44_RS12690	COG2814	Major facilitator Superfamily
EYS44_RS12695	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYS44_RS12695	COG2124	cytochrome p450
EYS44_RS12700	COG1309	transcriptional regulator
EYS44_RS12705	COG2226	methyltransferase
EYS44_RS12720	COG2116	formate transmembrane transporter activity
EYS44_RS12725	COG5609	conserved protein (DUF2294)
EYS44_RS12730	COG3383	formate dehydrogenase (NAD+) activity
EYS44_RS12735	COG2427	Protein of unknown function (DUF1641)
EYS44_RS12745	COG0626	cystathionine gamma-synthase activity
EYS44_RS12750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYS44_RS12775	COG0768	penicillin binding
EYS44_RS12790	COG0826	peptidase U32
EYS44_RS12795	COG0826	peptidase U32
EYS44_RS12800	COG4122	O-methyltransferase activity
EYS44_RS12805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYS44_RS12820	COG4472	Bacterial protein of unknown function (DUF965)
EYS44_RS12830	COG0628	permease
EYS44_RS12835	COG1126	abc transporter atp-binding protein
EYS44_RS12840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYS44_RS12845	COG0765	amino acid transport
EYS44_RS12850	COG0765	amino acid transport
EYS44_RS12865	COG3881	PFAM PRC-barrel domain
EYS44_RS12870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYS44_RS12875	COG0457	Tetratricopeptide repeat
EYS44_RS12885	COG1104	cysteine desulfurase activity
EYS44_RS12890	COG1959	2 iron, 2 sulfur cluster binding
EYS44_RS12895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYS44_RS12900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYS44_RS12920	COG4991	sh3 domain protein
EYS44_RS12920	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS12920	COG3103	Sh3 type 3 domain protein
EYS44_RS12930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYS44_RS12940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYS44_RS12940	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EYS44_RS12945	COG5416	Lipopolysaccharide assembly protein A domain
EYS44_RS12950	COG0490	domain, Protein
EYS44_RS12955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYS44_RS12955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYS44_RS12965	COG2244	polysaccharide biosynthetic process
EYS44_RS12970	COG2323	membrane
EYS44_RS12980	COG1862	Preprotein translocase
EYS44_RS13025	COG1388	LysM domain
EYS44_RS13035	COG0157	Belongs to the NadC ModD family
EYS44_RS13040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EYS44_RS13045	COG1104	cysteine desulfurase activity
EYS44_RS13050	COG1827	regulation of RNA biosynthetic process
EYS44_RS13055	COG0077	Prephenate dehydratase
EYS44_RS13070	COG3290	protein histidine kinase activity
EYS44_RS13075	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYS44_RS13080	COG2868	ribosomal protein
EYS44_RS13090	COG1994	Peptidase M50
EYS44_RS13095	COG0739	heme binding
EYS44_RS13100	COG2894	cell division
EYS44_RS13110	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EYS44_RS13120	COG1077	Cell shape determining protein MreB Mrl
EYS44_RS13140	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EYS44_RS13145	COG0285	dihydrofolate synthase activity
EYS44_RS13150	COG0525	valine-tRNA ligase activity
EYS44_RS13160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EYS44_RS13165	COG1388	LysM domain
EYS44_RS13175	COG0113	porphobilinogen synthase activity
EYS44_RS13180	COG1587	Uroporphyrinogen-III synthase
EYS44_RS13190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYS44_RS13210	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYS44_RS13215	COG0470	DNA polymerase III
EYS44_RS13215	COG1067	ATP-dependent peptidase activity
EYS44_RS13230	COG1477	protein flavinylation
EYS44_RS13230	COG0457	Tetratricopeptide repeat
EYS44_RS13245	COG0473	3-isopropylmalate dehydrogenase activity
EYS44_RS13260	COG0440	acetolactate synthase activity
EYS44_RS13265	COG0028	Belongs to the TPP enzyme family
EYS44_RS13290	COG0622	Phosphoesterase
EYS44_RS13295	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYS44_RS13305	COG5401	PFAM Sporulation and spore germination
EYS44_RS13315	COG1846	Transcriptional regulator
EYS44_RS13320	COG2197	response regulator
EYS44_RS13325	COG0824	Thioesterase
EYS44_RS13330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYS44_RS13335	COG1053	succinate dehydrogenase
EYS44_RS13340	COG2009	succinate dehydrogenase
EYS44_RS13345	COG1719	4-vinyl reductase, 4VR
EYS44_RS13350	COG0527	aspartate kinase activity
EYS44_RS13365	COG3118	belongs to the thioredoxin family
EYS44_RS13370	COG3534	alpha-L-arabinofuranosidase
EYS44_RS13375	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EYS44_RS13380	COG2086	electron transfer activity
EYS44_RS13385	COG1024	Enoyl-CoA hydratase
EYS44_RS13390	COG1309	transcriptional regulator
EYS44_RS13395	COG0318	PFAM AMP-dependent synthetase and ligase
EYS44_RS13405	COG3766	membrane
EYS44_RS13415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYS44_RS13415	COG1796	DNA polymerase
EYS44_RS13420	COG1286	toxin biosynthetic process
EYS44_RS13435	COG0072	phenylalanine-tRNA ligase activity
EYS44_RS13435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS44_RS13440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYS44_RS13445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYS44_RS13455	COG3835	regulator
EYS44_RS13460	COG0277	FAD linked oxidase domain protein
EYS44_RS13465	COG0247	lactate metabolic process
EYS44_RS13470	COG1966	Carbon starvation protein
EYS44_RS13475	COG3534	alpha-L-arabinofuranosidase
EYS44_RS13480	COG0395	ABC-type sugar transport system, permease component
EYS44_RS13485	COG1175	transmembrane transport
EYS44_RS13490	COG1653	transport
EYS44_RS13500	COG0647	UMP catabolic process
EYS44_RS13505	COG0235	Class ii aldolase
EYS44_RS13510	COG1069	ribulokinase activity
EYS44_RS13515	COG2160	L-arabinose isomerase activity
EYS44_RS13520	COG3507	Belongs to the glycosyl hydrolase 43 family
EYS44_RS13525	COG1363	Peptidase, m42
EYS44_RS13535	COG3326	Membrane
EYS44_RS13540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYS44_RS13550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYS44_RS13555	COG1346	cytolysis
EYS44_RS13560	COG1380	Effector of murein hydrolase LrgA
EYS44_RS13565	COG3279	Response regulator of the LytR AlgR family
EYS44_RS13570	COG3275	phosphorelay sensor kinase activity
EYS44_RS13575	COG1011	Hydrolase
EYS44_RS13590	COG0398	Pfam SNARE associated Golgi protein
EYS44_RS13595	COG1484	DNA-dependent DNA replication
EYS44_RS13600	COG3611	Membrane attachment protein
EYS44_RS13615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYS44_RS13620	COG1733	regulation of RNA biosynthetic process
EYS44_RS13625	COG2814	Major facilitator Superfamily
EYS44_RS13630	COG0656	L-ascorbic acid biosynthetic process
EYS44_RS13635	COG0237	dephospho-CoA kinase activity
EYS44_RS13640	COG1971	Probably functions as a manganese efflux pump
EYS44_RS13645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYS44_RS13650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYS44_RS13650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYS44_RS13655	COG5002	protein histidine kinase activity
EYS44_RS13660	COG0745	RESPONSE REGULATOR receiver
EYS44_RS13670	COG0538	isocitrate dehydrogenase activity
EYS44_RS13675	COG0372	Belongs to the citrate synthase family
EYS44_RS13695	COG0628	permease
EYS44_RS13700	COG3030	protein affecting phage T7 exclusion by the F plasmid
EYS44_RS13705	COG0469	pyruvate kinase activity
EYS44_RS13725	COG0281	malic enzyme
EYS44_RS13730	COG0587	DNA-directed DNA polymerase activity
EYS44_RS13750	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EYS44_RS13760	COG4109	DRTGG domain
EYS44_RS13770	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS13785	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYS44_RS13795	COG0827	DNA restriction-modification system
EYS44_RS13800	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EYS44_RS13805	COG3874	Sporulation protein YtfJ
EYS44_RS13815	COG1714	RDD family
EYS44_RS13820	COG0616	signal peptide processing
EYS44_RS13825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYS44_RS13830	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EYS44_RS13835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYS44_RS13850	COG1104	cysteine desulfurase activity
EYS44_RS13855	COG1114	Component of the transport system for branched-chain amino acids
EYS44_RS13865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYS44_RS13870	COG1309	transcriptional regulator
EYS44_RS13875	COG1956	GAF domain-containing protein
EYS44_RS13880	COG2199	diguanylate cyclase activity
EYS44_RS13880	COG2203	Gaf domain
EYS44_RS13895	COG1012	belongs to the aldehyde dehydrogenase family
EYS44_RS13900	COG4282	regulation of fungal-type cell wall biogenesis
EYS44_RS13910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EYS44_RS13910	COG1017	nitric oxide dioxygenase activity
EYS44_RS13920	COG0693	protein deglycase activity
EYS44_RS13935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYS44_RS13940	COG1378	Sugar-specific transcriptional regulator TrmB
EYS44_RS13965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYS44_RS13970	COG0454	-acetyltransferase
EYS44_RS13975	COG0517	IMP dehydrogenase activity
EYS44_RS13980	COG0123	including yeast histone deacetylase and acetoin utilization protein
EYS44_RS13985	COG1360	Flagellar Motor Protein
EYS44_RS13990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYS44_RS13995	COG1609	Transcriptional regulator
EYS44_RS14000	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EYS44_RS14000	COG1605	Chorismate mutase
EYS44_RS14005	COG3118	belongs to the thioredoxin family
EYS44_RS14010	COG4980	gas vesicle protein
EYS44_RS14015	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EYS44_RS14025	COG1674	ftsk spoiiie
EYS44_RS14030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS44_RS14040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYS44_RS14050	COG1363	Peptidase, m42
EYS44_RS14055	COG5584	Small secreted protein
EYS44_RS14060	COG0281	malic enzyme
EYS44_RS14065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYS44_RS14080	COG0510	thiamine kinase activity
EYS44_RS14085	COG1597	lipid kinase activity
EYS44_RS14095	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EYS44_RS14100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYS44_RS14105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYS44_RS14110	COG2252	PERMEase
EYS44_RS14115	COG4473	ABC transporter
EYS44_RS14120	COG1131	(ABC) transporter
EYS44_RS14130	COG1349	DNA-binding transcription factor activity
EYS44_RS14135	COG1187	pseudouridine synthase activity
EYS44_RS14140	COG2244	polysaccharide biosynthetic process
EYS44_RS14145	COG2081	HI0933 family
EYS44_RS14150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EYS44_RS14160	COG1609	Transcriptional regulator
EYS44_RS14165	COG1653	transport
EYS44_RS14170	COG1175	transmembrane transport
EYS44_RS14175	COG0395	ABC-type sugar transport system, permease component
EYS44_RS14180	COG1486	melibiose metabolic process
EYS44_RS14190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYS44_RS14205	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS44_RS14205	COG2202	Pas domain
EYS44_RS14210	COG2814	Major facilitator Superfamily
EYS44_RS14215	COG5522	Integral membrane protein (intg_mem_TP0381)
EYS44_RS14220	COG0577	efflux transmembrane transporter activity
EYS44_RS14225	COG1136	(ABC) transporter
EYS44_RS14230	COG2205	protein histidine kinase activity
EYS44_RS14240	COG0577	efflux transmembrane transporter activity
EYS44_RS14245	COG1136	(ABC) transporter
EYS44_RS14265	COG1131	(ABC) transporter
EYS44_RS14270	COG1725	Transcriptional regulator
EYS44_RS14280	COG0640	Transcriptional regulator
EYS44_RS14285	COG0477	Major facilitator Superfamily
EYS44_RS14290	COG1242	4 iron, 4 sulfur cluster binding
EYS44_RS14295	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EYS44_RS14305	COG0584	glycerophosphoryl diester phosphodiesterase
EYS44_RS14315	COG2267	carboxylic ester hydrolase activity
EYS44_RS14320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYS44_RS14325	COG1113	amino acid transport
EYS44_RS14330	COG0367	asparagine synthase
EYS44_RS14350	COG1506	peptidase
EYS44_RS14355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYS44_RS14360	COG1116	anion transmembrane transporter activity
EYS44_RS14365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYS44_RS14370	COG0494	nUDIX hydrolase
EYS44_RS14375	COG4824	toxin secretion phage lysis holin
EYS44_RS14380	COG0783	Belongs to the Dps family
EYS44_RS14405	COG0288	reversible hydration of carbon dioxide
EYS44_RS14415	COG1271	oxidase subunit
EYS44_RS14420	COG1294	oxidase, subunit
EYS44_RS14435	COG4948	Mandelate Racemase Muconate Lactonizing
EYS44_RS14445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EYS44_RS14450	COG0596	Alpha beta hydrolase
EYS44_RS14460	COG1169	isochorismate synthase
EYS44_RS14465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYS44_RS14470	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EYS44_RS14595	COG3859	Proton-coupled thiamine transporter YuaJ
EYS44_RS14600	COG2268	Band 7 protein
EYS44_RS14605	COG1585	Membrane protein implicated in regulation of membrane protease activity
EYS44_RS14610	COG2318	DinB family
EYS44_RS14620	COG1454	alcohol dehydrogenase
EYS44_RS14625	COG1012	belongs to the aldehyde dehydrogenase family
EYS44_RS14630	COG1510	regulation of RNA biosynthetic process
EYS44_RS14640	COG0569	domain protein
EYS44_RS14645	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYS44_RS14650	COG1017	nitric oxide dioxygenase activity
EYS44_RS14650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EYS44_RS14675	COG0628	permease
EYS44_RS14680	COG0673	inositol 2-dehydrogenase activity
EYS44_RS14685	COG0693	protein deglycase activity
EYS44_RS14690	COG0840	transmembrane signaling receptor activity
EYS44_RS14695	COG0840	transmembrane signaling receptor activity
EYS44_RS14700	COG0840	transmembrane signaling receptor activity
EYS44_RS14705	COG0840	transmembrane signaling receptor activity
EYS44_RS14720	COG2070	2-Nitropropane dioxygenase
EYS44_RS14725	COG0432	Pfam Uncharacterised protein family UPF0047
EYS44_RS14730	COG0366	Alpha amylase catalytic
EYS44_RS14735	COG1253	flavin adenine dinucleotide binding
EYS44_RS14740	COG2738	Putative neutral zinc metallopeptidase
EYS44_RS14755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYS44_RS14780	COG1335	isochorismatase
EYS44_RS14790	COG1979	alcohol dehydrogenase
EYS44_RS14795	COG1979	alcohol dehydrogenase
EYS44_RS14800	COG2155	Conserved Protein
EYS44_RS14805	COG1098	S1 RNA binding domain
EYS44_RS14810	COG0436	Aminotransferase
EYS44_RS14815	COG1522	sequence-specific DNA binding
EYS44_RS14820	COG2267	carboxylic ester hydrolase activity
EYS44_RS14830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EYS44_RS14835	COG2205	protein histidine kinase activity
EYS44_RS14845	COG5018	Exonuclease
EYS44_RS14850	COG2814	Major facilitator Superfamily
EYS44_RS14855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYS44_RS14860	COG3011	Protein conserved in bacteria
EYS44_RS14870	COG3290	protein histidine kinase activity
EYS44_RS14875	COG4565	transcriptional regulatory protein
EYS44_RS14880	COG1744	ABC transporter substrate-binding protein PnrA-like
EYS44_RS14885	COG3845	ABC transporter
EYS44_RS14890	COG4603	Belongs to the binding-protein-dependent transport system permease family
EYS44_RS14895	COG1079	Belongs to the binding-protein-dependent transport system permease family
EYS44_RS14905	COG2111	Na H antiporter
EYS44_RS14905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYS44_RS14910	COG2111	Na H antiporter
EYS44_RS14915	COG1006	Multisubunit Na H antiporter MnhC subunit
EYS44_RS14920	COG0651	ATP synthesis coupled electron transport
EYS44_RS14925	COG1863	multisubunit Na H antiporter MnhE subunit
EYS44_RS14930	COG2212	antiporter activity
EYS44_RS14935	COG1320	monovalent cation:proton antiporter activity
EYS44_RS14940	COG2050	protein possibly involved in aromatic compounds catabolism
EYS44_RS14945	COG2197	response regulator
EYS44_RS14950	COG4585	Histidine kinase
EYS44_RS14960	COG0142	geranyltranstransferase activity
EYS44_RS14975	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EYS44_RS14980	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYS44_RS14985	COG1335	isochorismatase
EYS44_RS14990	COG5506	Protein of unknown function (DUF1694)
EYS44_RS15005	COG0628	permease
EYS44_RS15015	COG1418	mRNA catabolic process
EYS44_RS15020	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS15030	COG1511	domain protein
EYS44_RS15035	COG1674	ftsk spoiiie
EYS44_RS15035	COG0433	COG0433 Predicted ATPase
EYS44_RS15040	COG4499	WXG100 protein secretion system (Wss), protein YukC
EYS44_RS15045	COG5417	Belongs to the EsaB family
EYS44_RS15050	COG4842	Belongs to the WXG100 family
EYS44_RS15055	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EYS44_RS15055	COG2508	Transcriptional regulator
EYS44_RS15060	COG0686	Belongs to the AlaDH PNT family
EYS44_RS15065	COG5634	Uncharacterized conserved protein (DUF2278)
EYS44_RS15070	COG3251	PFAM MbtH domain protein
EYS44_RS15075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYS44_RS15080	COG1535	isochorismatase
EYS44_RS15080	COG3433	isochorismatase activity
EYS44_RS15085	COG1021	2,3-dihydroxybenzoate-AMP ligase
EYS44_RS15090	COG1169	isochorismate synthase
EYS44_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS15100	COG2819	hydrolase of the alpha beta superfamily
EYS44_RS15105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYS44_RS15110	COG1268	BioY protein
EYS44_RS15115	COG2056	Na+-H+ antiporter family
EYS44_RS15125	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EYS44_RS15130	COG3584	3D domain protein
EYS44_RS15145	COG1252	NADH dehydrogenase
EYS44_RS15170	COG1131	(ABC) transporter
EYS44_RS15195	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EYS44_RS15200	COG0316	Belongs to the HesB IscA family
EYS44_RS15210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYS44_RS15220	COG1252	NADH dehydrogenase
EYS44_RS15225	COG4837	Protein of unknown function (DUF1462)
EYS44_RS15230	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EYS44_RS15235	COG4946	Tricorn protease homolog
EYS44_RS15235	COG1506	peptidase
EYS44_RS15235	COG0823	Involved in the tonB-independent uptake of proteins
EYS44_RS15245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYS44_RS15250	COG0460	homoserine dehydrogenase
EYS44_RS15255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EYS44_RS15260	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EYS44_RS15265	COG0647	UMP catabolic process
EYS44_RS15270	COG2445	Protein of unknown function DUF86
EYS44_RS15275	COG4470	Protein conserved in bacteria
EYS44_RS15290	COG0739	heme binding
EYS44_RS15300	COG0737	Belongs to the 5'-nucleotidase family
EYS44_RS15305	COG0730	response to heat
EYS44_RS15310	COG1801	Protein of unknown function DUF72
EYS44_RS15325	COG2508	Transcriptional regulator
EYS44_RS15340	COG2814	Major facilitator Superfamily
EYS44_RS15345	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYS44_RS15350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYS44_RS15355	COG2356	endonuclease I
EYS44_RS15360	COG3842	ATPase activity
EYS44_RS15365	COG2188	Transcriptional regulator
EYS44_RS15370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYS44_RS15375	COG0395	ABC-type sugar transport system, permease component
EYS44_RS15380	COG1175	transmembrane transport
EYS44_RS15385	COG1653	transport
EYS44_RS15390	COG2222	sugar isomerase
EYS44_RS15395	COG0789	Transcriptional regulator
EYS44_RS15410	COG0322	excinuclease ABC activity
EYS44_RS15415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYS44_RS15420	COG2226	methyltransferase
EYS44_RS15430	COG3409	Peptidoglycan-binding domain 1 protein
EYS44_RS15440	COG5632	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS15445	COG4824	toxin secretion phage lysis holin
EYS44_RS15465	COG5434	Belongs to the glycosyl hydrolase 28 family
EYS44_RS15480	COG5412	phage tail tape measure protein
EYS44_RS15480	COG3953	SLT domain
EYS44_RS15555	COG4980	gas vesicle protein
EYS44_RS15555	COG1674	ftsk spoiiie
EYS44_RS15560	COG0582	viral genome integration into host DNA
EYS44_RS15565	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYS44_RS15640	COG1396	sequence-specific DNA binding
EYS44_RS15640	COG3800	Transcriptional regulator
EYS44_RS15660	COG0719	Fe-S assembly protein
EYS44_RS15665	COG0822	iron-sulfur transferase activity
EYS44_RS15670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYS44_RS15675	COG0719	Fe-S assembly protein
EYS44_RS15680	COG0396	ATPase activity
EYS44_RS15690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYS44_RS15695	COG1464	Belongs to the NlpA lipoprotein family
EYS44_RS15700	COG2011	ABC-type metal ion transport system permease component
EYS44_RS15705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYS44_RS15715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYS44_RS15720	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EYS44_RS15735	COG1393	Belongs to the ArsC family
EYS44_RS15740	COG1960	acyl-CoA dehydrogenase activity
EYS44_RS15745	COG0183	Belongs to the thiolase family
EYS44_RS15750	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYS44_RS15750	COG1024	Enoyl-CoA hydratase
EYS44_RS15765	COG0477	Major facilitator Superfamily
EYS44_RS15775	COG5577	PFAM Coat F domain
EYS44_RS15780	COG1846	Transcriptional regulator
EYS44_RS15785	COG0477	Major facilitator Superfamily
EYS44_RS15790	COG0583	DNA-binding transcription factor activity
EYS44_RS15810	COG1120	ATPase activity
EYS44_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS15830	COG0783	Belongs to the Dps family
EYS44_RS15835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYS44_RS15845	COG0745	RESPONSE REGULATOR receiver
EYS44_RS15850	COG2770	Histidine kinase
EYS44_RS15850	COG2205	protein histidine kinase activity
EYS44_RS15860	COG1309	transcriptional regulator
EYS44_RS15865	COG0114	fumarate hydratase activity
EYS44_RS15875	COG0697	spore germination
EYS44_RS15880	COG0814	amino acid
EYS44_RS15890	COG2197	response regulator
EYS44_RS15895	COG4585	Histidine kinase
EYS44_RS15900	COG4758	membrane
EYS44_RS15905	COG3595	metallopeptidase activity
EYS44_RS15910	COG1842	Phage shock protein A
EYS44_RS15915	COG4758	membrane
EYS44_RS15920	COG2814	Major facilitator Superfamily
EYS44_RS15925	COG2096	Adenosyltransferase
EYS44_RS15930	COG1120	ATPase activity
EYS44_RS15935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS44_RS15940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYS44_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS15950	COG3386	PFAM SMP-30 Gluconolaconase
EYS44_RS15955	COG2205	protein histidine kinase activity
EYS44_RS15960	COG0745	RESPONSE REGULATOR receiver
EYS44_RS15970	COG1191	sigma factor activity
EYS44_RS15980	COG2140	Oxalate decarboxylase
EYS44_RS15990	COG1120	ATPase activity
EYS44_RS15995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS44_RS16000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS44_RS16005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYS44_RS16010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EYS44_RS16015	COG0531	amino acid
EYS44_RS16030	COG1988	membrane-bound metal-dependent
EYS44_RS16035	COG1368	sulfuric ester hydrolase activity
EYS44_RS16040	COG1910	domain protein
EYS44_RS16045	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYS44_RS16050	COG4149	molybdate abc transporter
EYS44_RS16055	COG2197	response regulator
EYS44_RS16060	COG3850	Histidine kinase
EYS44_RS16065	COG1131	(ABC) transporter
EYS44_RS16075	COG0842	Transport permease protein
EYS44_RS16080	COG0656	L-ascorbic acid biosynthetic process
EYS44_RS16105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYS44_RS16110	COG3973	AAA domain
EYS44_RS16115	COG2860	membrane
EYS44_RS16125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EYS44_RS16130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYS44_RS16135	COG2217	Heavy metal translocating P-type atpase
EYS44_RS16140	COG2217	Heavy metal translocating P-type atpase
EYS44_RS16145	COG2608	mercury ion transmembrane transporter activity
EYS44_RS16150	COG1937	Protein conserved in bacteria
EYS44_RS16155	COG0673	inositol 2-dehydrogenase activity
EYS44_RS16175	COG2814	Major facilitator Superfamily
EYS44_RS16190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYS44_RS16195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EYS44_RS16200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYS44_RS16205	COG1126	abc transporter atp-binding protein
EYS44_RS16210	COG0765	amino acid transport
EYS44_RS16215	COG0765	amino acid transport
EYS44_RS16220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYS44_RS16225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYS44_RS16230	COG0454	-acetyltransferase
EYS44_RS16235	COG0583	DNA-binding transcription factor activity
EYS44_RS16240	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS16245	COG2732	(Barnase) inhibitor
EYS44_RS16265	COG4824	toxin secretion phage lysis holin
EYS44_RS16285	COG5434	Belongs to the glycosyl hydrolase 28 family
EYS44_RS16290	COG1388	LysM domain
EYS44_RS16290	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYS44_RS16365	COG4626	Terminase
EYS44_RS16365	COG1802	Transcriptional regulator
EYS44_RS16395	COG0582	viral genome integration into host DNA
EYS44_RS16400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYS44_RS16525	COG0582	viral genome integration into host DNA
EYS44_RS16540	COG0557	exoribonuclease II activity
EYS44_RS16545	COG1647	Serine aminopeptidase, S33
EYS44_RS16550	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYS44_RS16555	COG1476	TRANSCRIPTIONal
EYS44_RS16560	COG1396	sequence-specific DNA binding
EYS44_RS16565	COG1396	sequence-specific DNA binding
EYS44_RS16570	COG1733	regulation of RNA biosynthetic process
EYS44_RS16595	COG1131	(ABC) transporter
EYS44_RS16600	COG1174	glycine betaine transport
EYS44_RS16605	COG1732	Glycine betaine
EYS44_RS16610	COG1174	glycine betaine transport
EYS44_RS16615	COG0517	IMP dehydrogenase activity
EYS44_RS16615	COG1125	glycine betaine transport
EYS44_RS16620	COG1510	regulation of RNA biosynthetic process
EYS44_RS16625	COG1174	glycine betaine transport
EYS44_RS16630	COG1732	Glycine betaine
EYS44_RS16635	COG1174	glycine betaine transport
EYS44_RS16640	COG1125	glycine betaine transport
EYS44_RS16640	COG0517	IMP dehydrogenase activity
EYS44_RS16645	COG1510	regulation of RNA biosynthetic process
EYS44_RS16650	COG2095	MarC family integral membrane protein
EYS44_RS16655	COG3064	Membrane
EYS44_RS16660	COG4640	response to antibiotic
EYS44_RS16665	COG0456	acetyltransferase
EYS44_RS16680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYS44_RS16695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYS44_RS16700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYS44_RS16705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYS44_RS16715	COG2234	aminopeptidase activity
EYS44_RS16735	COG0126	phosphoglycerate kinase activity
EYS44_RS16745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYS44_RS16750	COG2390	Transcriptional regulator
EYS44_RS16755	COG2814	Major facilitator Superfamily
EYS44_RS16760	COG1609	Transcriptional regulator
EYS44_RS16765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYS44_RS16775	COG0583	DNA-binding transcription factor activity
EYS44_RS16780	COG0697	spore germination
EYS44_RS16785	COG1113	amino acid transport
EYS44_RS16790	COG1737	Transcriptional regulator
EYS44_RS16795	COG1070	Carbohydrate kinase
EYS44_RS16820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYS44_RS16825	COG2186	Transcriptional regulator
EYS44_RS16830	COG1620	l-lactate permease
EYS44_RS16835	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EYS44_RS16845	COG5039	Polysaccharide pyruvyl transferase
EYS44_RS16850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYS44_RS16855	COG0110	maltose O-acetyltransferase activity
EYS44_RS16860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYS44_RS16865	COG2244	polysaccharide biosynthetic process
EYS44_RS16870	COG1216	Glycosyl transferase, family 2
EYS44_RS16875	COG5039	Polysaccharide pyruvyl transferase
EYS44_RS16880	COG1216	Glycosyl transferase, family 2
EYS44_RS16890	COG0438	transferase activity, transferring glycosyl groups
EYS44_RS16895	COG1215	transferase activity, transferring glycosyl groups
EYS44_RS16900	COG0438	transferase activity, transferring glycosyl groups
EYS44_RS16905	COG1086	Polysaccharide biosynthesis protein
EYS44_RS16910	COG0489	protein tyrosine kinase activity
EYS44_RS16915	COG3944	biosynthesis protein
EYS44_RS16920	COG1396	sequence-specific DNA binding
EYS44_RS16925	COG2272	Belongs to the type-B carboxylesterase lipase family
EYS44_RS16935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EYS44_RS16940	COG2364	Membrane
EYS44_RS16945	COG0456	acetyltransferase
EYS44_RS16950	COG3479	Phenolic acid decarboxylase
EYS44_RS17005	COG2223	nitrite transmembrane transporter activity
EYS44_RS17010	COG1609	Transcriptional regulator
EYS44_RS17020	COG0583	DNA-binding transcription factor activity
EYS44_RS17025	COG2828	Protein conserved in bacteria
EYS44_RS17030	COG0477	Major facilitator Superfamily
EYS44_RS17030	COG2814	Major facilitator Superfamily
EYS44_RS17035	COG1611	Belongs to the LOG family
EYS44_RS17040	COG1694	Mazg nucleotide pyrophosphohydrolase
EYS44_RS17045	COG0659	secondary active sulfate transmembrane transporter activity
EYS44_RS17050	COG0288	reversible hydration of carbon dioxide
EYS44_RS17060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYS44_RS17065	COG4290	ribonuclease
EYS44_RS17070	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EYS44_RS17075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS44_RS17085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EYS44_RS17095	COG1051	belongs to the nudix hydrolase family
EYS44_RS17100	COG0492	ferredoxin-NADP+ reductase activity
EYS44_RS17105	COG3883	PFAM NLP P60 protein
EYS44_RS17105	COG0791	NLP P60 protein
EYS44_RS17110	COG0457	Tetratricopeptide repeat
EYS44_RS17115	COG5002	protein histidine kinase activity
EYS44_RS17120	COG0745	RESPONSE REGULATOR receiver
EYS44_RS17130	COG1132	(ABC) transporter
EYS44_RS17135	COG0140	phosphoribosyl-ATP diphosphatase activity
EYS44_RS17135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYS44_RS17160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EYS44_RS17175	COG4990	cell redox homeostasis
EYS44_RS17180	COG0110	maltose O-acetyltransferase activity
EYS44_RS17200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYS44_RS17210	COG2188	Transcriptional regulator
EYS44_RS17215	COG1309	transcriptional regulator
EYS44_RS17220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EYS44_RS17225	COG1950	PFAM Membrane protein of
EYS44_RS17230	COG1983	PspC domain protein
EYS44_RS17235	COG3595	metallopeptidase activity
EYS44_RS17250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYS44_RS17260	COG4897	Protein conserved in bacteria
EYS44_RS17265	COG3848	Pyruvate phosphate dikinase
EYS44_RS17265	COG0574	Belongs to the PEP-utilizing enzyme family
EYS44_RS17270	COG1309	transcriptional regulator
EYS44_RS17275	COG2814	Major facilitator Superfamily
EYS44_RS17285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYS44_RS17295	COG3409	Peptidoglycan-binding domain 1 protein
EYS44_RS17295	COG0793	Belongs to the peptidase S41A family
EYS44_RS17300	COG3420	alginic acid biosynthetic process
EYS44_RS17305	COG2177	Part of the ABC transporter FtsEX involved in
EYS44_RS17310	COG2884	Cell division ATP-binding protein ftsE
EYS44_RS17315	COG2010	Cytochrome c
EYS44_RS17320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYS44_RS17335	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EYS44_RS17350	COG1516	flagellar protein fliS
EYS44_RS17355	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EYS44_RS17360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYS44_RS17380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYS44_RS17385	COG4786	Flagellar basal body rod
EYS44_RS17385	COG1256	bacterial-type flagellum assembly
EYS44_RS17390	COG3418	PFAM FlgN family protein
EYS44_RS17395	COG2747	anti-sigma28 factor FlgM
EYS44_RS17405	COG1040	competence protein
EYS44_RS17415	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EYS44_RS17420	COG1307	EDD domain protein, DegV family
EYS44_RS17425	COG2197	response regulator
EYS44_RS17430	COG4585	Histidine kinase
EYS44_RS17435	COG1739	Uncharacterized protein family UPF0029
EYS44_RS17440	COG1316	TRANSCRIPTIONal
EYS44_RS17445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYS44_RS17450	COG0438	transferase activity, transferring glycosyl groups
EYS44_RS17455	COG1215	transferase activity, transferring glycosyl groups
EYS44_RS17460	COG3206	protein involved in exopolysaccharide biosynthesis
EYS44_RS17465	COG3307	-O-antigen
EYS44_RS17470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EYS44_RS17475	COG0438	transferase activity, transferring glycosyl groups
EYS44_RS17475	COG0297	glycogen (starch) synthase activity
EYS44_RS17480	COG2244	polysaccharide biosynthetic process
EYS44_RS17490	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYS44_RS17490	COG2247	cell wall binding repeat
EYS44_RS17495	COG2247	cell wall binding repeat
EYS44_RS17495	COG2385	sporulation resulting in formation of a cellular spore
EYS44_RS17505	COG1316	TRANSCRIPTIONal
EYS44_RS17510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EYS44_RS17515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYS44_RS17520	COG1134	teichoic acid transport
EYS44_RS17525	COG1682	transport, permease protein
EYS44_RS17530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYS44_RS17540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EYS44_RS17545	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EYS44_RS17550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYS44_RS17555	COG4193	domain, Protein
EYS44_RS17560	COG1482	cell wall glycoprotein biosynthetic process
EYS44_RS17565	COG0697	spore germination
EYS44_RS17570	COG0814	amino acid
EYS44_RS17580	COG1215	transferase activity, transferring glycosyl groups
EYS44_RS17585	COG2814	Major facilitator Superfamily
EYS44_RS17590	COG1316	TRANSCRIPTIONal
EYS44_RS17595	COG0561	phosphatase activity
EYS44_RS17600	COG2433	Pfam Transposase IS66
EYS44_RS17605	COG0791	NLP P60 protein
EYS44_RS17615	COG2843	Capsule synthesis protein
EYS44_RS17625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYS44_RS17635	COG0697	spore germination
EYS44_RS17640	COG0814	amino acid
EYS44_RS17650	COG1609	Transcriptional regulator
EYS44_RS17655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYS44_RS17665	COG1129	ABC transporter
EYS44_RS17670	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYS44_RS17675	COG1879	ABC-type sugar transport system periplasmic component
EYS44_RS17680	COG3103	Sh3 type 3 domain protein
EYS44_RS17685	COG2249	NAD(P)H dehydrogenase (quinone) activity
EYS44_RS17690	COG3527	Alpha-acetolactate decarboxylase
EYS44_RS17695	COG0028	Belongs to the TPP enzyme family
EYS44_RS17700	COG0583	DNA-binding transcription factor activity
EYS44_RS17705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EYS44_RS17720	COG5337	Spore coat protein CotH
EYS44_RS17730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYS44_RS17740	COG0405	Gamma-glutamyltransferase
EYS44_RS17745	COG1522	sequence-specific DNA binding
EYS44_RS17750	COG2059	Chromate
EYS44_RS17755	COG2059	Chromate
EYS44_RS17765	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYS44_RS17770	COG0583	DNA-binding transcription factor activity
EYS44_RS17815	COG5444	nuclease activity
EYS44_RS17830	COG3878	Protein conserved in bacteria
EYS44_RS17835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EYS44_RS17840	COG4464	protein tyrosine phosphatase activity
EYS44_RS17845	COG0489	protein tyrosine kinase activity
EYS44_RS17850	COG3944	biosynthesis protein
EYS44_RS17865	COG4715	Zinc finger, swim domain protein
EYS44_RS17870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYS44_RS17875	COG0561	phosphatase activity
EYS44_RS17880	COG1349	DNA-binding transcription factor activity
EYS44_RS17885	COG0629	single-stranded DNA binding
EYS44_RS17910	COG0457	Tetratricopeptide repeat
EYS44_RS17915	COG4786	Flagellar basal body rod
EYS44_RS17920	COG4786	Flagellar basal body rod
EYS44_RS17925	COG1077	Cell shape determining protein MreB Mrl
EYS44_RS17930	COG1609	Transcriptional regulator
EYS44_RS17935	COG1846	Transcriptional regulator
EYS44_RS17940	COG2814	Major facilitator Superfamily
EYS44_RS17945	COG1953	Uracil, thiamine, allantoin
EYS44_RS17950	COG0477	Major facilitator Superfamily
EYS44_RS17955	COG1335	isochorismatase
EYS44_RS17960	COG0004	ammonium transporteR
EYS44_RS17965	COG0347	Belongs to the P(II) protein family
EYS44_RS17970	COG0772	Belongs to the SEDS family
EYS44_RS17975	COG0671	phosphoesterase, PA-phosphatase related
EYS44_RS17985	COG0739	heme binding
EYS44_RS17990	COG1247	-acetyltransferase
EYS44_RS18005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYS44_RS18015	COG0726	polysaccharide deacetylase
EYS44_RS18025	COG1959	2 iron, 2 sulfur cluster binding
EYS44_RS18040	COG0831	urea catabolic process
EYS44_RS18045	COG3237	CsbD-like
EYS44_RS18050	COG1994	Peptidase M50
EYS44_RS18055	COG0457	Tetratricopeptide repeat
EYS44_RS18065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EYS44_RS18070	COG2304	oxidoreductase activity
EYS44_RS18075	COG2304	oxidoreductase activity
EYS44_RS18080	COG2385	sporulation resulting in formation of a cellular spore
EYS44_RS18085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYS44_RS18095	COG4836	Membrane
EYS44_RS18165	COG0698	ribose 5-phosphate isomerase
EYS44_RS18170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYS44_RS18180	COG0009	L-threonylcarbamoyladenylate synthase
EYS44_RS18185	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EYS44_RS18205	COG2890	protein-(glutamine-N5) methyltransferase activity
EYS44_RS18210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYS44_RS18215	COG0346	lactoylglutathione lyase activity
EYS44_RS18220	COG0789	Transcriptional regulator
EYS44_RS18225	COG0679	Auxin Efflux Carrier
EYS44_RS18230	COG0281	malic enzyme
EYS44_RS18245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYS44_RS18250	COG1494	fructose-1,6-bisphosphatase
EYS44_RS18255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYS44_RS18265	COG0191	fructose-bisphosphate aldolase activity
EYS44_RS18270	COG2204	response regulator
EYS44_RS18275	COG4821	SIS domain
EYS44_RS18290	COG2181	nitrate reductase activity
EYS44_RS18290	COG0247	lactate metabolic process
EYS44_RS18295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYS44_RS18315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYS44_RS18325	COG2181	nitrate reductase activity
EYS44_RS18330	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EYS44_RS18335	COG1140	nitrate reductase beta subunit
EYS44_RS18340	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EYS44_RS18345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYS44_RS18355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYS44_RS18360	COG2223	nitrite transmembrane transporter activity
EYS44_RS18370	COG4506	Protein conserved in bacteria
EYS44_RS18375	COG0457	Tetratricopeptide repeat
EYS44_RS18410	COG0018	arginyl-trna synthetase
EYS44_RS18415	COG0010	Belongs to the arginase family
EYS44_RS18420	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EYS44_RS18425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYS44_RS18440	COG1994	Peptidase M50
EYS44_RS18445	COG1942	4-Oxalocrotonate Tautomerase
EYS44_RS18450	COG1846	Transcriptional regulator
EYS44_RS18460	COG0531	amino acid
EYS44_RS18465	COG3465	dGTPase activity
EYS44_RS18470	COG1078	dGTPase activity
EYS44_RS18485	COG1695	Transcriptional regulator
EYS44_RS18505	COG0583	DNA-binding transcription factor activity
EYS44_RS18510	COG2855	membrane
EYS44_RS18515	COG0280	phosphate acetyltransferase
EYS44_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS18530	COG0436	Aminotransferase
EYS44_RS18560	COG2814	Major facilitator Superfamily
EYS44_RS18565	COG2814	Major facilitator Superfamily
EYS44_RS18570	COG0833	amino acid
EYS44_RS18575	COG4187	Peptidase family M20/M25/M40
EYS44_RS18580	COG1012	belongs to the aldehyde dehydrogenase family
EYS44_RS18585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYS44_RS18595	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EYS44_RS18600	COG1091	dTDP-4-dehydrorhamnose reductase activity
EYS44_RS18605	COG1088	dTDP-glucose 4,6-dehydratase activity
EYS44_RS18610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EYS44_RS18615	COG3980	spore coat polysaccharide biosynthesis protein
EYS44_RS18620	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EYS44_RS18625	COG2089	acid synthase
EYS44_RS18630	COG0456	acetyltransferase
EYS44_RS18635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYS44_RS18640	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYS44_RS18645	COG0463	Glycosyl transferase, family 2
EYS44_RS18655	COG2363	Small membrane protein
EYS44_RS18660	COG2233	PERMEase
EYS44_RS18675	COG1216	Glycosyl transferase, family 2
EYS44_RS18690	COG1695	Transcriptional regulator
EYS44_RS18695	COG0351	phosphomethylpyrimidine kinase
EYS44_RS18705	COG1621	beta-fructofuranosidase activity
EYS44_RS18710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYS44_RS18710	COG1263	PTS System
EYS44_RS18715	COG3711	transcriptional antiterminator
EYS44_RS18725	COG1404	Belongs to the peptidase S8 family
EYS44_RS18730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYS44_RS18735	COG0778	Nitroreductase
EYS44_RS18740	COG0772	Belongs to the SEDS family
EYS44_RS18745	COG0454	-acetyltransferase
EYS44_RS18765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYS44_RS18770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYS44_RS18775	COG2261	transglycosylase associated protein
EYS44_RS18780	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EYS44_RS18790	COG2246	polysaccharide biosynthetic process
EYS44_RS18795	COG1309	transcriptional regulator
EYS44_RS18815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EYS44_RS18820	COG2837	iron assimilation
EYS44_RS18845	COG0583	DNA-binding transcription factor activity
EYS44_RS18855	COG1346	cytolysis
EYS44_RS18860	COG4895	conserved protein (DUF2196)
EYS44_RS18865	COG0789	Transcriptional regulator
EYS44_RS18870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYS44_RS18875	COG0346	lactoylglutathione lyase activity
EYS44_RS18880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYS44_RS18885	COG1404	Belongs to the peptidase S8 family
EYS44_RS18890	COG1442	glycosyl transferase family 8
EYS44_RS18895	COG2357	RelA SpoT domain protein
EYS44_RS18900	COG1575	Belongs to the MenA family. Type 1 subfamily
EYS44_RS18925	COG1696	Membrane protein involved in D-alanine export
EYS44_RS18935	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EYS44_RS18940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYS44_RS18945	COG1486	melibiose metabolic process
EYS44_RS18950	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYS44_RS18955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYS44_RS18960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYS44_RS18965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS44_RS18965	COG3711	transcriptional antiterminator
EYS44_RS18980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS44_RS18985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS44_RS18995	COG0640	Transcriptional regulator
EYS44_RS19000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EYS44_RS19005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYS44_RS19010	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYS44_RS19015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYS44_RS19020	COG2723	6-phospho-beta-galactosidase activity
EYS44_RS19025	COG1940	carbohydrate kinase activity
EYS44_RS19030	COG1482	cell wall glycoprotein biosynthetic process
EYS44_RS19040	COG0753	catalase activity
EYS44_RS19045	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EYS44_RS19050	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EYS44_RS19055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYS44_RS19060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYS44_RS19065	COG4988	ABC transporter
EYS44_RS19070	COG1294	oxidase, subunit
EYS44_RS19075	COG1271	oxidase subunit
EYS44_RS19080	COG3493	citrate carrier protein
EYS44_RS19085	COG0726	polysaccharide deacetylase
EYS44_RS19090	COG3842	ATPase activity
EYS44_RS19095	COG2508	Transcriptional regulator
EYS44_RS19100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYS44_RS19110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYS44_RS19120	COG4894	glucomannan catabolic process
EYS44_RS19125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EYS44_RS19130	COG0500	methyltransferase
EYS44_RS19135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYS44_RS19150	COG0693	protein deglycase activity
EYS44_RS19150	COG0753	catalase activity
EYS44_RS19155	COG2851	Citrate transporter
EYS44_RS19160	COG2273	Hydrolase Family 16
EYS44_RS19170	COG2270	Major facilitator Superfamily
EYS44_RS19175	COG0513	Belongs to the DEAD box helicase family
EYS44_RS19240	COG0697	spore germination
EYS44_RS19245	COG0589	response to stress
EYS44_RS19300	COG3507	Belongs to the glycosyl hydrolase 43 family
EYS44_RS19325	COG0010	Belongs to the arginase family
EYS44_RS19330	COG0833	amino acid
EYS44_RS19335	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EYS44_RS19340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYS44_RS19350	COG2390	Transcriptional regulator
EYS44_RS19355	COG0561	phosphatase activity
EYS44_RS19385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYS44_RS19390	COG5294	Protein conserved in bacteria
EYS44_RS19395	COG0577	efflux transmembrane transporter activity
EYS44_RS19400	COG1136	(ABC) transporter
EYS44_RS19405	COG2205	protein histidine kinase activity
EYS44_RS19410	COG0745	RESPONSE REGULATOR receiver
EYS44_RS19425	COG1082	Xylose isomerase domain protein TIM barrel
EYS44_RS19435	COG2814	Major facilitator Superfamily
EYS44_RS19465	COG1349	DNA-binding transcription factor activity
EYS44_RS19470	COG0667	Aldo Keto reductase
EYS44_RS19475	COG2814	Major facilitator Superfamily
EYS44_RS19490	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS19495	COG2197	response regulator
EYS44_RS19500	COG4585	Histidine kinase
EYS44_RS19505	COG3239	Fatty acid desaturase
EYS44_RS19515	COG1309	transcriptional regulator
EYS44_RS19520	COG1012	belongs to the aldehyde dehydrogenase family
EYS44_RS19525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYS44_RS19535	COG0640	Transcriptional regulator
EYS44_RS19540	COG2814	Major facilitator Superfamily
EYS44_RS19545	COG1714	RDD family
EYS44_RS19555	COG0450	alkyl hydroperoxide reductase
EYS44_RS19560	COG3634	alkyl hydroperoxide reductase activity
EYS44_RS19565	COG1113	amino acid transport
EYS44_RS19575	COG2080	2 iron, 2 sulfur cluster binding
EYS44_RS19590	COG2068	MobA-Related Protein
EYS44_RS19595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYS44_RS19635	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EYS44_RS19640	COG0667	Aldo Keto reductase
EYS44_RS19645	COG0456	acetyltransferase
EYS44_RS19650	COG0457	Tetratricopeptide repeat
EYS44_RS19655	COG0010	Belongs to the arginase family
EYS44_RS19660	COG0833	amino acid
EYS44_RS19665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYS44_RS19670	COG3829	transcription factor binding
EYS44_RS19680	COG0488	(ABC) transporter
EYS44_RS19695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYS44_RS19700	COG3850	Histidine kinase
EYS44_RS19700	COG5002	protein histidine kinase activity
EYS44_RS19710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYS44_RS19715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EYS44_RS19720	COG4853	Protein conserved in bacteria
EYS44_RS19725	COG4863	YycH protein
EYS44_RS19730	COG5002	protein histidine kinase activity
EYS44_RS19735	COG0745	RESPONSE REGULATOR receiver
EYS44_RS19770	COG0346	lactoylglutathione lyase activity
EYS44_RS19775	COG0305	Participates in initiation and elongation during chromosome replication
EYS44_RS19790	COG3093	addiction module antidote protein HigA
EYS44_RS19795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYS44_RS19800	COG0297	glycogen (starch) synthase activity
EYS44_RS19810	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EYS44_RS19815	COG0438	transferase activity, transferring glycosyl groups
EYS44_RS19825	COG0515	serine threonine protein kinase
EYS44_RS19835	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EYS44_RS19840	COG4241	membrane
EYS44_RS19850	COG5577	PFAM Coat F domain
EYS44_RS19855	COG1733	regulation of RNA biosynthetic process
EYS44_RS19865	COG0697	spore germination
EYS44_RS19870	COG1621	beta-fructofuranosidase activity
EYS44_RS19875	COG1621	beta-fructofuranosidase activity
EYS44_RS19880	COG1802	Transcriptional regulator
EYS44_RS19885	COG2318	DinB family
EYS44_RS19890	COG2211	Major facilitator Superfamily
EYS44_RS19900	COG0778	Nitroreductase
EYS44_RS19905	COG1846	Transcriptional regulator
EYS44_RS19910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYS44_RS19915	COG1846	Transcriptional regulator
EYS44_RS19930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYS44_RS19935	COG0583	DNA-binding transcription factor activity
EYS44_RS19940	COG1028	Short-chain dehydrogenase reductase Sdr
EYS44_RS19950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYS44_RS19955	COG0697	spore germination
EYS44_RS19960	COG1331	Highly conserved protein containing a thioredoxin domain
EYS44_RS19975	COG1959	2 iron, 2 sulfur cluster binding
EYS44_RS19980	COG1396	sequence-specific DNA binding
EYS44_RS19990	COG1331	Highly conserved protein containing a thioredoxin domain
EYS44_RS19995	COG1266	CAAX protease self-immunity
EYS44_RS20000	COG2814	Major facilitator Superfamily
EYS44_RS20000	COG0477	Major facilitator Superfamily
EYS44_RS20005	COG0346	lactoylglutathione lyase activity
EYS44_RS20010	COG1609	Transcriptional regulator
EYS44_RS20015	COG0708	Exodeoxyribonuclease III
EYS44_RS20020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYS44_RS20025	COG2169	Transcriptional regulator
EYS44_RS20035	COG0629	single-stranded DNA binding
EYS44_RS20045	COG0012	GTP binding
EYS44_RS20050	COG0243	molybdopterin cofactor binding
EYS44_RS20055	COG4481	Protein conserved in bacteria
EYS44_RS20060	COG3949	Membrane
EYS44_RS20075	COG1475	DNA binding
EYS44_RS20080	COG1192	Involved in chromosome partitioning
EYS44_RS20105	COG1847	R3H domain protein
EYS44_RS20110	COG0706	membrane insertase activity
EYS44_RS20125	COG0386	Belongs to the glutathione peroxidase family
EYS44_RS20295	COG1349	DNA-binding transcription factor activity
EYS44_RS20325	COG0191	fructose-bisphosphate aldolase activity
EYS44_RS20335	COG4821	SIS domain
EYS44_RS20370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYS44_RS20380	COG2056	Na+-H+ antiporter family