locus-tag class description FQV73_RS00010 ENOG4105MA6 gCN5-related N-acetyltransferase FQV73_RS00020 ENOG4108VPT UPF0234 protein FQV73_RS00025 ENOG4105QNR S1 RNA binding domain protein FQV73_RS00030 ENOG4105DIH basic membrane FQV73_RS00035 ENOG4105C8Q Methyl-accepting chemotaxis FQV73_RS00045 ENOG4105EPR degv family FQV73_RS00050 ENOG4107AYK membrAne FQV73_RS00060 ENOG41073B9 FQV73_RS00070 ENOG4108KP7 hydrolase FQV73_RS00075 ENOG4108MXZ Esterase FQV73_RS00080 ENOG4105VG1 fes assembly suf system protein FQV73_RS00085 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) FQV73_RS00090 ENOG4105IQ5 FAD linked oxidase domain protein FQV73_RS00100 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FQV73_RS00105 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FQV73_RS00110 ENOG4105CAS nag kinase FQV73_RS00115 ENOG4105C8Y Acetylornithine aminotransferase FQV73_RS00120 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FQV73_RS00130 ENOG4105DBV ornithine carbamoyltransferase FQV73_RS00155 ENOG4107RMD Basic membrane lipoprotein FQV73_RS00170 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FQV73_RS00175 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FQV73_RS00185 ENOG4105C3U ABC transporter FQV73_RS00190 ENOG4108JQ7 (ABC) transporter FQV73_RS00205 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FQV73_RS00225 ENOG4105C31 Tryptophanyl-tRNA synthetase FQV73_RS00230 ENOG4108J59 Extracellular solute-binding protein, family 5 FQV73_RS00235 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FQV73_RS00240 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FQV73_RS00250 ENOG4108JQ7 (ABC) transporter FQV73_RS00265 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) FQV73_RS00270 ENOG4108ZCF integral membrane protein FQV73_RS00275 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis FQV73_RS00285 ENOG4105DPN Oligoendopeptidase f FQV73_RS00295 ENOG4105T58 Dithiol-disulfide isomerase FQV73_RS00300 ENOG4108Z18 K06886 hemoglobin FQV73_RS00305 ENOG4105E4C Lytic transglycosylase catalytic FQV73_RS00310 ENOG4105MIX Adenylate cyclase FQV73_RS00325 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FQV73_RS00330 ENOG4105EMS pseudouridine synthase FQV73_RS00335 ENOG4107S1Q Phosphatase FQV73_RS00345 ENOG4105ETU transcriptional activator (TenA FQV73_RS00350 ENOG4108VEU Thiamine monophosphate synthase FQV73_RS00370 ENOG4105D06 uba thif-type nad fad binding protein FQV73_RS00375 ENOG4105DWF phosphomethylpyrimidine kinase FQV73_RS00380 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FQV73_RS00385 ENOG4107A88 FQV73_RS00435 ENOG4105ENA helicase FQV73_RS00455 ENOG4105CJ1 ABC, transporter FQV73_RS00470 ENOG4108ZMI UPF0477 protein FQV73_RS00480 ENOG4105C28 cystathionine FQV73_RS00485 ENOG4105C28 cystathionine FQV73_RS00500 ENOG4106BHF FQV73_RS00510 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase FQV73_RS00540 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase FQV73_RS00545 ENOG4105CMR udp-glucose 4-epimerase FQV73_RS00550 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) FQV73_RS00555 ENOG4105CK1 PTS System FQV73_RS00560 ENOG4105VCP PTS System FQV73_RS00570 ENOG4105E98 transcriptional regulator DeoR family FQV73_RS00590 ENOG4105KT7 mgtC SapB transporter FQV73_RS00615 ENOG4108IEG Formate dehydrogenase Alpha subunit FQV73_RS00625 ENOG4106A3M Cytochrome p-450 FQV73_RS00630 ENOG41087PP glycosyltransferase MGT family FQV73_RS00640 ENOG4105EXQ uroporphyrinogen iii synthase hem4 FQV73_RS00645 ENOG4105C4B ABC transporter, permease FQV73_RS00650 ENOG4108IXI (ABC) transporter FQV73_RS00660 ENOG4105Q95 Cupin 2, conserved barrel domain protein FQV73_RS00675 ENOG4105D2H Uronic isomerase FQV73_RS00680 ENOG4105CT4 transporter FQV73_RS00685 ENOG4107KJX Transcriptional regulator FQV73_RS00690 ENOG4105CTX dehydratase FQV73_RS00695 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FQV73_RS00700 ENOG4105F3H Histidine kinase FQV73_RS00720 ENOG4105BZU Histidine kinase FQV73_RS00725 ENOG4105WH1 Two component transcriptional regulator luxr family FQV73_RS00740 ENOG4108JJA ABC, transporter FQV73_RS00760 ENOG4107TSN permease FQV73_RS00780 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase FQV73_RS00785 ENOG4105KWG Pfam:DUF1696 FQV73_RS00790 ENOG4105K7W phage-related replication protein FQV73_RS00795 ENOG410635T phage-like element pbsx protein FQV73_RS00840 ENOG4108TFU terminase (Small subunit) FQV73_RS00845 ENOG4105IG6 Phage terminase, large subunit FQV73_RS00850 ENOG4108MDF Phage Portal Protein FQV73_RS00875 ENOG41060SN FQV73_RS00890 ENOG4105PQS phage protein FQV73_RS00895 ENOG4105FR7 XkdM protein, phage-like element PBSX FQV73_RS00900 ENOG4105MTC XkdN-like protein FQV73_RS00910 ENOG4108FKH Transglycosylase SLT domain FQV73_RS00910 ENOG4108FKH Transglycosylase SLT domain FQV73_RS00910 ENOG4108FKH Transglycosylase SLT domain FQV73_RS00915 ENOG4108WZM domain protein FQV73_RS00920 ENOG4105X7F FQV73_RS00930 ENOG4105MFU Protein of unknown function (DUF2634) FQV73_RS00935 ENOG41066EA baseplate J family protein FQV73_RS00940 ENOG410906S phage-like element pbsx protein xkdt FQV73_RS00950 ENOG41068G1 FQV73_RS00980 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FQV73_RS00995 ENOG4105CJ3 phosphate transporter FQV73_RS01000 ENOG4107GRR phosphate transport regulator FQV73_RS01005 ENOG4107R7I amino acid FQV73_RS01015 ENOG4105EDW glycosyl transferase, family 39 FQV73_RS01020 ENOG4105CKK Glycosyl transferase, family 2 FQV73_RS01025 ENOG4105C0H protease FQV73_RS01035 ENOG4108ME1 Peptidase M55 D-aminopeptidase FQV73_RS01040 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FQV73_RS01045 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FQV73_RS01050 ENOG4105C3U ABC transporter FQV73_RS01060 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FQV73_RS01065 ENOG4105DTQ mandelate racemase muconate lactonizing FQV73_RS01070 ENOG4107SN7 NLP P60 protein FQV73_RS01075 ENOG4108JQ7 (ABC) transporter FQV73_RS01080 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FQV73_RS01085 ENOG4107TUM Amidinotransferase FQV73_RS01090 ENOG4108S4H thioesterase Superfamily protein FQV73_RS01095 ENOG4108428 Inherit from COG: -acetyltransferase FQV73_RS01105 ENOG41080TC multidrug resistance protein FQV73_RS01110 ENOG4105CIY formyltetrahydrofolate deformylase FQV73_RS01115 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FQV73_RS01130 ENOG4105K56 Transcriptional regulator FQV73_RS01135 ENOG4108ZHJ Organic hydroperoxide resistance protein FQV73_RS01150 ENOG4107TVC Glycosyl transferase, family 2 FQV73_RS01160 ENOG4105D8G Major Facilitator superfamily FQV73_RS01165 ENOG4108Y4K DNA-binding transcriptional activator FQV73_RS01170 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) FQV73_RS01175 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FQV73_RS01185 ENOG4108W7F transporter, permease FQV73_RS01190 ENOG4108JJB ABC transporter FQV73_RS01195 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein FQV73_RS01200 ENOG4105VRS hydrolase family 18 FQV73_RS01215 ENOG4105CJW magnesium transporter FQV73_RS01220 ENOG4105V75 Transcriptional regulator FQV73_RS01245 ENOG4105DQE DNA ligase FQV73_RS01250 ENOG4105FDF Could be involved in DNA repair (By similarity) FQV73_RS01255 ENOG4107T5V SNARE associated Golgi FQV73_RS01260 ENOG4107TS3 membrane protein, TerC FQV73_RS01265 ENOG4108WZW RNA polymerase sigma FQV73_RS01275 ENOG410681C small acid-soluble spore protein FQV73_RS01285 ENOG4105D0M Protease HtpX homolog FQV73_RS01295 ENOG410900G Protein of unknown function (DUF421) FQV73_RS01305 ENOG4108TGC Acyltransferase FQV73_RS01310 ENOG4105BZU Histidine kinase FQV73_RS01315 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FQV73_RS01320 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) FQV73_RS01330 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FQV73_RS01340 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate FQV73_RS01345 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) FQV73_RS01350 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) FQV73_RS01355 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) FQV73_RS01365 ENOG4105BZU Histidine kinase FQV73_RS01370 ENOG41090MY MarR family Transcriptional regulator FQV73_RS01375 ENOG4105ER2 Ompa motb domain protein FQV73_RS01380 ENOG4105E14 MotA TolQ exbB proton channel FQV73_RS01390 ENOG4108K88 Membrane FQV73_RS01400 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) FQV73_RS01405 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase FQV73_RS01410 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FQV73_RS01415 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) FQV73_RS01465 ENOG4105F0V Cell wall hydrolase FQV73_RS01480 ENOG4105C59 p-type ATPase FQV73_RS01485 ENOG4105DC7 peptidase M24 FQV73_RS01495 ENOG4105CID antiterminator FQV73_RS01505 ENOG4105KRI phosphocarrier protein (HPr FQV73_RS01510 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FQV73_RS01520 ENOG4105F6S Spore photoproduct lyase FQV73_RS01525 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FQV73_RS01530 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FQV73_RS01545 ENOG4105K4I Scp-like extracellular FQV73_RS01555 ENOG4105BZU Histidine kinase FQV73_RS01560 ENOG4105CHM Aminotransferase FQV73_RS01570 ENOG4107R88 Chemotaxis protein (CheV) FQV73_RS01575 ENOG4105UIN FQV73_RS01585 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein FQV73_RS01595 ENOG4105K6S Short-chain dehydrogenase reductase Sdr FQV73_RS01605 ENOG4105EPM Diguanylate phosphodiesterase FQV73_RS01610 ENOG4107IN1 Protein of unknown function (DUF1797) FQV73_RS01615 ENOG4108XRC Protein of unknown function (DUF458) FQV73_RS01645 ENOG4105NQC Flavodoxin FQV73_RS01665 ENOG4105D8X mechanosensitive ion channel FQV73_RS01670 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FQV73_RS01685 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FQV73_RS01690 ENOG4105D06 uba thif-type nad fad binding protein FQV73_RS01695 ENOG4105CVM Molybdenum cofactor synthesis domain protein FQV73_RS01700 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FQV73_RS01705 ENOG4108ZAF Molybdopterin FQV73_RS01710 ENOG41067WU Molybdopterin converting factor (Subunit 1) FQV73_RS01720 ENOG4107X8C Efflux transporter RND family MFP subunit FQV73_RS01725 ENOG4105C19 ABC transporter FQV73_RS01730 ENOG4107RBB ABC transporter, permease FQV73_RS01735 ENOG4105E98 transcriptional regulator DeoR family FQV73_RS01740 ENOG4105DE4 1-phosphofructokinase FQV73_RS01745 ENOG4105DM4 PTS System FQV73_RS01760 ENOG4105C5H ABC transporter FQV73_RS01765 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FQV73_RS01790 ENOG4105BZU Histidine kinase FQV73_RS01800 ENOG4107ZYR domain protein FQV73_RS01805 ENOG4105CPN adenine deaminase FQV73_RS01810 ENOG4105CN5 Metallo-Beta-Lactamase FQV73_RS01815 ENOG4106148 UPF0356 protein FQV73_RS01820 ENOG4108X4Q Hydrolase FQV73_RS01825 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FQV73_RS01840 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FQV73_RS01845 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS01850 ENOG4107SQU synthase FQV73_RS01855 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS01860 ENOG4107SQU synthase FQV73_RS01865 ENOG4107SQU synthase FQV73_RS01870 ENOG4107SQU synthase FQV73_RS01875 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS01880 ENOG4105FQP Beta-lactamase FQV73_RS01890 ENOG4105CPP Dehydrogenase, E1 component FQV73_RS01895 ENOG4105C7S Dehydrogenase FQV73_RS01900 ENOG4107QN2 dihydrolipoyl dehydrogenase FQV73_RS01920 ENOG4105CXN decarboxylase FQV73_RS01925 ENOG4105WBI UPF0223 protein FQV73_RS01940 ENOG4105ECY inositol monophosphatase FQV73_RS01950 ENOG4105D4Y metalloprotease FQV73_RS01985 ENOG4105CI3 gtp-binding protein typa FQV73_RS01990 ENOG4105QA2 FQV73_RS02005 ENOG4108IAB Phoh family FQV73_RS02015 ENOG4105CSV Glutaminase FQV73_RS02025 ENOG4105CNI cell division protein FtsW FQV73_RS02030 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FQV73_RS02040 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) FQV73_RS02050 ENOG4105BZ9 Cytochrome C oxidase, subunit I FQV73_RS02055 ENOG4105CCU oxidase (Subunit III) FQV73_RS02060 ENOG41064X9 cytochrome C oxidase subunit IV FQV73_RS02075 ENOG41080XQ Signal transduction protein with cbs domains FQV73_RS02080 ENOG4106UY4 Inherit from COG: Scp-like extracellular FQV73_RS02110 ENOG4106H78 methyltransferase FQV73_RS02115 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FQV73_RS02120 ENOG4105H20 Sporulation integral membrane protein YlbJ FQV73_RS02125 ENOG4105D78 K07001 NTE family protein FQV73_RS02130 ENOG41063PX domain protein FQV73_RS02135 ENOG4105CDE UPF0348 protein FQV73_RS02140 ENOG4105KNH Nucleic acid-binding protein FQV73_RS02170 ENOG4108V6E Cell division protein mraZ FQV73_RS02175 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) FQV73_RS02185 ENOG4105CJN penicillin-binding protein FQV73_RS02190 ENOG4105CJN penicillin-binding protein FQV73_RS02195 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FQV73_RS02200 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FQV73_RS02205 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FQV73_RS02210 ENOG4105CNI cell division protein FtsW FQV73_RS02215 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FQV73_RS02220 ENOG4105D4A Cell wall formation (By similarity) FQV73_RS02225 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) FQV73_RS02230 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FQV73_RS02235 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FQV73_RS02245 ENOG4105FFI sigma-e processing peptidase spoiiga FQV73_RS02250 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FQV73_RS02260 ENOG4105DKW ABC transporter FQV73_RS02270 ENOG4105WR5 sporulation protein, YlmC YmxH family FQV73_RS02275 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FQV73_RS02280 ENOG4105DFA alanine racemase domain protein FQV73_RS02285 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) FQV73_RS02290 ENOG41067XK integral membrane protein FQV73_RS02295 ENOG4105DBK s4 domain protein FQV73_RS02305 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FQV73_RS02315 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FQV73_RS02320 ENOG4105C34 Pseudouridine synthase FQV73_RS02325 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) FQV73_RS02335 ENOG4105CXT aspartate transcarbamylase FQV73_RS02345 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FQV73_RS02350 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FQV73_RS02355 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) FQV73_RS02360 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) FQV73_RS02365 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) FQV73_RS02370 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FQV73_RS02385 ENOG4107RIQ Sulfate adenylate transferase FQV73_RS02395 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FQV73_RS02400 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FQV73_RS02405 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FQV73_RS02420 ENOG4105DSJ YicC domain protein FQV73_RS02425 ENOG4105KC4 UPF0296 protein FQV73_RS02430 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FQV73_RS02440 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FQV73_RS02445 ENOG4105C25 Primosomal protein n' FQV73_RS02450 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FQV73_RS02455 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FQV73_RS02460 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FQV73_RS02465 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs FQV73_RS02470 ENOG4108ZF3 Phosphatase FQV73_RS02475 ENOG4105D9P serine threonine protein kinase FQV73_RS02480 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FQV73_RS02485 ENOG4105DJV ribulose-phosphate 3-epimerase FQV73_RS02490 ENOG4105FJ0 thiamine FQV73_RS02500 ENOG4105VB9 50S ribosomal protein l28 FQV73_RS02505 ENOG4108ZAA Alkaline-shock protein FQV73_RS02510 ENOG4105DP4 dak2 domain fusion protein ylov FQV73_RS02520 ENOG4105EJQ L-serine dehydratase FQV73_RS02525 ENOG4105CB5 ATP-dependent DNA helicase recG FQV73_RS02530 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) FQV73_RS02535 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) FQV73_RS02540 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FQV73_RS02545 ENOG4105CHR reductase FQV73_RS02555 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FQV73_RS02560 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FQV73_RS02565 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FQV73_RS02575 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) FQV73_RS02585 ENOG4105K5M 30s ribosomal protein S16 FQV73_RS02590 ENOG4108BW8 UPF0109 protein FQV73_RS02605 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) FQV73_RS02610 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FQV73_RS02615 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FQV73_RS02620 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FQV73_RS02630 ENOG4105VM1 flagellar FQV73_RS02635 ENOG4105CMV Succinyl-CoA synthetase subunit beta FQV73_RS02640 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FQV73_RS02645 ENOG4105C79 DNA protecting protein DprA FQV73_RS02650 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FQV73_RS02655 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) FQV73_RS02660 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FQV73_RS02665 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) FQV73_RS02670 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) FQV73_RS02680 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FQV73_RS02685 ENOG4108ZC9 flagellar basal-body rod protein flgc FQV73_RS02690 ENOG4105VQ0 flagellar hook-basal body complex protein fliE FQV73_RS02695 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) FQV73_RS02700 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FQV73_RS02715 ENOG4106YF4 Flagellar biosynthesis chaperone FQV73_RS02725 ENOG410696Y Flagellar hook-length control protein FQV73_RS02730 ENOG410822I Flagellar hook capping protein FQV73_RS02735 ENOG4108JQA flagellar FQV73_RS02740 ENOG41068WV flagellar FlbD family protein FQV73_RS02750 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FQV73_RS02755 ENOG4105DD5 Flagellar motor switch protein FQV73_RS02760 ENOG4107YTP response regulator receiver protein FQV73_RS02770 ENOG4105CN7 Flagellar biosynthetic protein FliP FQV73_RS02775 ENOG4105VS8 Flagellar biosynthetic protein fliq FQV73_RS02780 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FQV73_RS02785 ENOG4105D00 flagellar biosynthetic protein flhB FQV73_RS02790 ENOG4105D7B Flagellar biosynthesis protein flha FQV73_RS02795 ENOG4105FZW flagellar biosynthesis regulator FlhF FQV73_RS02805 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FQV73_RS02810 ENOG4105CBS Chea signal transduction histidine kinase FQV73_RS02815 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis FQV73_RS02825 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) FQV73_RS02830 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FQV73_RS02840 ENOG4105CE9 30S ribosomal protein S2 FQV73_RS02850 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FQV73_RS02855 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FQV73_RS02860 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FQV73_RS02865 ENOG4105KNE Phosphatidate cytidylyltransferase FQV73_RS02875 ENOG4105DZP Membrane-associated zinc metalloprotease FQV73_RS02880 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) FQV73_RS02885 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FQV73_RS02890 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) FQV73_RS02895 ENOG4105CHV Transcription elongation factor NusA FQV73_RS02900 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FQV73_RS02905 ENOG4105VHM ribosomal protein FQV73_RS02910 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) FQV73_RS02915 ENOG4105W7A Protein of unknown function (DUF503) FQV73_RS02920 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) FQV73_RS02925 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FQV73_RS02930 ENOG4105DTN riboflavin biosynthesis protein ribF FQV73_RS02935 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) FQV73_RS02940 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FQV73_RS02950 ENOG4105C1V Peptidase, M16 FQV73_RS02960 ENOG4105E35 Dipicolinate synthase subunit A FQV73_RS02965 ENOG4108S0H Dipicolinic acid synthetase, b subunit FQV73_RS02970 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FQV73_RS02980 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FQV73_RS02990 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FQV73_RS03000 ENOG4105CNU cell division protein FtsK FQV73_RS03005 ENOG4105FDP GntR family transcriptional regulator FQV73_RS03020 ENOG4105EYF MMPL domain protein FQV73_RS03035 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FQV73_RS03040 ENOG4105XZV Protein of unknown function (DUF3243) FQV73_RS03055 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FQV73_RS03060 ENOG4105CEV competence damage-inducible protein FQV73_RS03065 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) FQV73_RS03070 ENOG4108A04 Beta-lactamase FQV73_RS03080 ENOG4105D48 metallophosphoesterase FQV73_RS03085 ENOG4105MCT stage V sporulation protein S FQV73_RS03090 ENOG4105CPQ Dehydrogenase FQV73_RS03095 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FQV73_RS03100 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FQV73_RS03120 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FQV73_RS03125 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) FQV73_RS03135 ENOG4108IMY Transcriptional regulator FQV73_RS03245 ENOG410682Q Phage transcriptional regulator, ArpU FQV73_RS03350 ENOG4108FKH Transglycosylase SLT domain FQV73_RS03360 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FQV73_RS03370 ENOG41068G1 FQV73_RS03390 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FQV73_RS03415 ENOG4108151 Beta-lactamase domain protein FQV73_RS03420 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FQV73_RS03425 ENOG4108JA1 polyketide synthase FQV73_RS03430 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FQV73_RS03435 ENOG41062T2 Acyl carrier protein FQV73_RS03440 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase FQV73_RS03445 ENOG4108MGH Enoyl-CoA hydratase FQV73_RS03450 ENOG4108KQ6 Enoyl-CoA hydratase FQV73_RS03455 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS03460 ENOG4107SQU synthase FQV73_RS03470 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS03480 ENOG4106A3M Cytochrome p-450 FQV73_RS03485 ENOG4105WFK nuclease FQV73_RS03490 ENOG4105XPP Protein of unknown function (DUF1275) FQV73_RS03500 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FQV73_RS03510 ENOG4105K7W phage-related replication protein FQV73_RS03515 ENOG4108X3M OsmC Ohr family protein FQV73_RS03540 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FQV73_RS03565 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FQV73_RS03570 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FQV73_RS03575 ENOG4105U6W MutT NUDIX family protein FQV73_RS03590 ENOG4106F1P AAA ATPase, central domain protein FQV73_RS03595 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FQV73_RS03600 ENOG4105CXI aluminum resistance protein FQV73_RS03605 ENOG4105KV4 Transcriptional regulator FQV73_RS03610 ENOG4105C5F glutamine synthetase FQV73_RS03620 ENOG4105CT4 transporter FQV73_RS03625 ENOG4105DSG hydrolase family 43 FQV73_RS03635 ENOG4105C93 Xylose Isomerase FQV73_RS03640 ENOG4105CMG Carbohydrate kinase FQV73_RS03645 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FQV73_RS03665 ENOG4105DQ4 alcohol dehydrogenase FQV73_RS03695 ENOG4108M1A Chitin-binding protein FQV73_RS03720 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FQV73_RS03725 ENOG4105K7W phage-related replication protein FQV73_RS03750 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FQV73_RS03760 ENOG4108SVB resolvase FQV73_RS03765 ENOG4105VPS UPF0291 protein FQV73_RS03770 ENOG4105CV1 Transketolase (EC 2.2.1.1) FQV73_RS03780 ENOG4105VXM UPF0154 protein FQV73_RS03790 ENOG4107QIV Cytochrome c biogenesis protein FQV73_RS03825 ENOG4108I0Z Aconitate hydratase FQV73_RS03830 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FQV73_RS03845 ENOG41067CD Small, acid-soluble spore protein Tlp FQV73_RS03855 ENOG4105MI2 FQV73_RS03860 ENOG4105W8X HesB YadR YfhF-family protein FQV73_RS03865 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) FQV73_RS03870 ENOG4105K4P CoA-binding domain protein FQV73_RS03875 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FQV73_RS03900 ENOG4105CPQ Dehydrogenase FQV73_RS03905 ENOG4108UHU Aldolase FQV73_RS03910 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) FQV73_RS03915 ENOG4105DMW Dehydrogenase reductase FQV73_RS03925 ENOG4108I5G Major Facilitator superfamily FQV73_RS03940 ENOG4105FVX FQV73_RS03980 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FQV73_RS03990 ENOG4107SYN Glycosyl hydrolases family 43 FQV73_RS04015 ENOG4105DTD Dehydrogenase FQV73_RS04020 ENOG4108IIH CoA-transferase subunit B FQV73_RS04025 ENOG4105D6N CoA-transferase, subunit a FQV73_RS04030 ENOG4105CY2 Citrate transporter FQV73_RS04035 ENOG4106A3M Cytochrome p-450 FQV73_RS04040 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) FQV73_RS04045 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FQV73_RS04050 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FQV73_RS04055 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FQV73_RS04060 ENOG4108W8G Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity) FQV73_RS04070 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FQV73_RS04075 ENOG4107T5V SNARE associated Golgi FQV73_RS04080 ENOG4107QX3 carboxylase FQV73_RS04085 ENOG4105E39 Enoyl-CoA hydratase FQV73_RS04090 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FQV73_RS04095 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FQV73_RS04100 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FQV73_RS04105 ENOG4105CEY Amp-dependent synthetase and ligase FQV73_RS04110 ENOG4105C1G acyl-Coa dehydrogenase FQV73_RS04115 ENOG4105F32 YngK protein FQV73_RS04120 ENOG4106U2H Protein of unknown function (DUF1360) FQV73_RS04130 ENOG4105CEY Amp-dependent synthetase and ligase FQV73_RS04135 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS04145 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS04150 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family FQV73_RS04155 ENOG4108N2V aldose 1-epimerase FQV73_RS04160 ENOG4107QJQ Mate efflux family protein FQV73_RS04185 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FQV73_RS04190 ENOG4108RWP Major Facilitator Superfamily protein FQV73_RS04195 ENOG4105WAB arsR family transcriptional regulator FQV73_RS04200 ENOG4105C22 threonyL-tRNA synthetase FQV73_RS04205 ENOG4108KSA LysR family transcriptional regulator FQV73_RS04210 ENOG4105CB2 alcohol dehydrogenase FQV73_RS04215 ENOG4105BZ8 glutamate synthase FQV73_RS04220 ENOG4105CBC glutamate synthase FQV73_RS04225 ENOG4105C5Q Transcriptional regulator FQV73_RS04230 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FQV73_RS04255 ENOG4108UB7 FQV73_RS04260 ENOG4105IE8 Alpha-ketoglutarate permease FQV73_RS04265 ENOG4107U6E carbohydrate kinase FGGY FQV73_RS04270 ENOG4108M3J Dehydrogenase FQV73_RS04275 ENOG4108J2R molybdopterin oxidoreductase FQV73_RS04295 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr FQV73_RS04305 ENOG4108Z7R Chaperone CsaA FQV73_RS04310 ENOG4105FTV AraC Family Transcriptional Regulator FQV73_RS04320 ENOG4108W8B Beta-lactamase domain protein FQV73_RS04330 ENOG4105KTU Transcriptional regulator, arsr family FQV73_RS04340 ENOG4108SJC Membrane FQV73_RS04365 ENOG41069ER domain protein FQV73_RS04370 ENOG4105C9U ATP-dependent DNA helicase RecQ FQV73_RS04380 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FQV73_RS04385 ENOG4105SCY DNAK suppressor FQV73_RS04430 ENOG4105C26 Dehydrogenase FQV73_RS04435 ENOG4105EWU Squalene--hopene cyclase FQV73_RS04440 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FQV73_RS04445 ENOG4105C8J )-transporter FQV73_RS04450 ENOG4105C09 Bile acid FQV73_RS04460 ENOG4105C7S Dehydrogenase FQV73_RS04465 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FQV73_RS04470 ENOG4107T89 von Willebrand factor, type A FQV73_RS04475 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FQV73_RS04485 ENOG4105K4H Nlp p60 protein FQV73_RS04490 ENOG41087PP glycosyltransferase MGT family FQV73_RS04500 ENOG4107QMU Mate efflux family protein FQV73_RS04505 ENOG4106SCS STAS domain FQV73_RS04525 ENOG4105FR1 rard protein FQV73_RS04540 ENOG41090U3 tautomerase FQV73_RS04560 ENOG4105FBA Phospholipase Carboxylesterase FQV73_RS04575 ENOG4105E1V na solute symporter FQV73_RS04585 ENOG4105CS2 ec 3.2.1.21 FQV73_RS04590 ENOG4108S3Y transcriptional regulator FQV73_RS04610 ENOG4108VXD carboxy-peptidase FQV73_RS04615 ENOG4105D3A purine nucleoside phosphorylase DeoD-type FQV73_RS04625 ENOG4106Z5R FQV73_RS04630 ENOG410841Q phosphoesterase PA-phosphatase related protein FQV73_RS04665 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FQV73_RS04670 ENOG4108TSC N-acetyltransferase FQV73_RS04675 ENOG4107S4Y M20 DapE family protein YgeY FQV73_RS04690 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FQV73_RS04695 ENOG4105FTQ Dna gyrase FQV73_RS04825 ENOG4106ANW SMI1_KNR4 FQV73_RS04830 ENOG4106BHF FQV73_RS04855 ENOG4105E0X reductase FQV73_RS04860 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FQV73_RS04870 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) FQV73_RS04875 ENOG41090WU lipolytic protein G-D-S-L family FQV73_RS04880 ENOG4108KF3 Electron transport protein SCO1 SenC FQV73_RS04890 ENOG4105C7B Threonine dehydratase FQV73_RS04900 ENOG4108UT2 hemolysin iii FQV73_RS04910 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FQV73_RS04915 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) FQV73_RS04925 ENOG4107YX5 Pfam:DUF548 FQV73_RS04930 ENOG4108Y6J UPF0403 protein FQV73_RS04935 ENOG4105C01 Dihydroxy-acid dehydratase FQV73_RS04950 ENOG4108V06 Glutathione peroxidase FQV73_RS04955 ENOG4105CVG Homoserine O-transsuccinylase FQV73_RS05000 ENOG41081VK Ribonuclease FQV73_RS05025 ENOG410890F Dynamin family FQV73_RS05040 ENOG41065KQ synthase FQV73_RS05075 ENOG4105C2W permease FQV73_RS05080 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) FQV73_RS05085 ENOG4105CTD carboxy-peptidase FQV73_RS05090 ENOG4105DVT helicase FQV73_RS05110 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FQV73_RS05120 ENOG4105XWG Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity) FQV73_RS05125 ENOG4108UKS UPF0398 protein FQV73_RS05140 ENOG4107X2U Inherit from COG: Exonuclease-like protein FQV73_RS05145 ENOG4108I5C dEAD DEAH box helicase FQV73_RS05190 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) FQV73_RS05195 ENOG4105BZ4 penicillin-binding protein FQV73_RS05205 ENOG4105CSM endonuclease III FQV73_RS05215 ENOG4105C5S asparaginyl-tRNA synthetase FQV73_RS05220 ENOG4105CHM Aminotransferase FQV73_RS05230 ENOG4105YAC FQV73_RS05235 ENOG4105DVT helicase FQV73_RS05240 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) FQV73_RS05250 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) FQV73_RS05260 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate FQV73_RS05265 ENOG4105CPK Glycosyl transferase (Group 1 FQV73_RS05270 ENOG4105FJR Lmbe family FQV73_RS05275 ENOG4108Z5K methylglyoxal synthase FQV73_RS05280 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) FQV73_RS05285 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FQV73_RS05290 ENOG4108JYZ YitT family FQV73_RS05295 ENOG4105F0F Oxalate decarboxylase FQV73_RS05315 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FQV73_RS05335 ENOG41068YB TPR repeat-containing protein FQV73_RS05340 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FQV73_RS05350 ENOG4105CIH Imidazole acetol-phosphate transaminase FQV73_RS05360 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FQV73_RS05365 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase FQV73_RS05370 ENOG4105DK0 Indole-3-glycerol phosphate synthase FQV73_RS05380 ENOG4105CRQ synthase (Component I) FQV73_RS05385 ENOG4105KHN chorismate mutase FQV73_RS05395 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase FQV73_RS05400 ENOG4105BZU Histidine kinase FQV73_RS05405 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) FQV73_RS05410 ENOG4105EAH synthase FQV73_RS05415 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FQV73_RS05420 ENOG4105XXQ heptaprenyl diphosphate synthase component I FQV73_RS05425 ENOG4105WP2 Tryptophan RNA-binding attenuator protein FQV73_RS05430 ENOG4105EUJ GTP cyclohydrolase i FQV73_RS05435 ENOG4105K70 DNA-binding protein FQV73_RS05440 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FQV73_RS05455 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase FQV73_RS05460 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FQV73_RS05480 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FQV73_RS05485 ENOG4105CAT Cytidine monophosphate kinase FQV73_RS05500 ENOG4105MSI germination protein ypeb FQV73_RS05510 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) FQV73_RS05515 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FQV73_RS05530 ENOG4107RGJ metallophosphoesterase FQV73_RS05545 ENOG4105I7S Abortive infection protein FQV73_RS05550 ENOG4105C9U ATP-dependent DNA helicase RecQ FQV73_RS05555 ENOG4105T7X FQV73_RS05565 ENOG4108SAX Membrane FQV73_RS05570 ENOG4108JQ1 Dehydrogenase FQV73_RS05585 ENOG4105BZU Histidine kinase FQV73_RS05590 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FQV73_RS05595 ENOG4105CRE cytochrome C FQV73_RS05600 ENOG4107TWT Cytochrome c biogenesis protein FQV73_RS05610 ENOG4105FE9 pseudouridine synthase FQV73_RS05620 ENOG4108JIC nucleoside recognition domain protein FQV73_RS05625 ENOG4105DZ1 carboxypeptidase FQV73_RS05635 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FQV73_RS05640 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FQV73_RS05660 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FQV73_RS05665 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FQV73_RS05670 ENOG4108R6K riboflavin synthase, subunit alpha FQV73_RS05695 ENOG4107ZE5 PPIases accelerate the folding of proteins FQV73_RS05700 ENOG4105PTM secreted protein FQV73_RS05705 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FQV73_RS05715 ENOG4105G6R Stage v sporulation protein ae FQV73_RS05725 ENOG4105CZ3 stage V sporulation protein ad FQV73_RS05730 ENOG41090VF Stage v sporulation protein ac FQV73_RS05745 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FQV73_RS05750 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) FQV73_RS05755 ENOG41082AN stage II sporulation protein FQV73_RS05760 ENOG4105DZ1 carboxypeptidase FQV73_RS05765 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) FQV73_RS05770 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FQV73_RS05775 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FQV73_RS05785 ENOG4105I3K Ferric uptake regulator, Fur family FQV73_RS05790 ENOG4105MZ9 stage II sporulation protein m FQV73_RS05810 ENOG4105DFD Na H antiporter FQV73_RS05815 ENOG4108IJ0 Aspartate ammonia-lyase FQV73_RS05820 ENOG4105HDK L-asparaginase FQV73_RS05825 ENOG4108IMY Transcriptional regulator FQV73_RS05835 ENOG4108YZ4 nudix hydrolase FQV73_RS05845 ENOG4105CPC Aldo Keto reductase FQV73_RS05865 ENOG4106HZJ FQV73_RS05870 ENOG4105RHY Pfam:UPF0157 FQV73_RS05875 ENOG4105KAC Antibiotic biosynthesis monooxygenase FQV73_RS05880 ENOG4108XET gCN5-related N-acetyltransferase FQV73_RS05885 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FQV73_RS05900 ENOG4105C02 permease FQV73_RS05910 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase FQV73_RS05915 ENOG4105CS9 pantothenic acid kinase FQV73_RS05925 ENOG4108IXY short-chain dehydrogenase reductase FQV73_RS05930 ENOG41069FQ Metallo-beta-lactamase superfamily FQV73_RS05935 ENOG4105II7 pyrroline-5-carboxylate reductase FQV73_RS05940 ENOG4108KQ6 Enoyl-CoA hydratase FQV73_RS05945 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase FQV73_RS05950 ENOG4106A3M Cytochrome p-450 FQV73_RS05965 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS05970 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS05980 ENOG4105C0W non-ribosomal peptide synthetase FQV73_RS05990 ENOG4105CHR reductase FQV73_RS05995 ENOG4105CEY Amp-dependent synthetase and ligase FQV73_RS06010 ENOG4107QKG PfaD family FQV73_RS06015 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FQV73_RS06020 ENOG4108K70 Transcriptional regulator FQV73_RS06030 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FQV73_RS06040 ENOG410861F 50S ribosomal protein L33 FQV73_RS06045 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FQV73_RS06050 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FQV73_RS06055 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FQV73_RS06060 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FQV73_RS06070 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) FQV73_RS06075 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FQV73_RS06080 ENOG4108HNZ carboxyl transferase FQV73_RS06085 ENOG4108ZVT methylmalonyl-coA epimerase FQV73_RS06095 ENOG4108VZI ErfK ybiS ycfS ynhG family protein FQV73_RS06100 ENOG4108QEG Membrane FQV73_RS06105 ENOG4105CDA abc transporter atp-binding protein FQV73_RS06110 ENOG4105E5Q amino acid AbC transporter FQV73_RS06115 ENOG4108HW3 (ABC) transporter FQV73_RS06120 ENOG4108Y6J UPF0403 protein FQV73_RS06125 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FQV73_RS06130 ENOG4105C7S Dehydrogenase FQV73_RS06135 ENOG4105CPP Dehydrogenase, E1 component FQV73_RS06150 ENOG4105CKM Branched-chain carboxylic acid kinase FQV73_RS06155 ENOG4107RDP Dehydrogenase FQV73_RS06165 ENOG4108JUB Transcriptional regulator FQV73_RS06170 ENOG4106CCJ Protein of unknown function (DUF2627) FQV73_RS06175 ENOG4105CR4 methylisocitrate lyase FQV73_RS06180 ENOG4105DXD 2-methylcitrate dehydratase FQV73_RS06190 ENOG4105C1G acyl-Coa dehydrogenase FQV73_RS06195 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FQV73_RS06205 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FQV73_RS06210 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FQV73_RS06235 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FQV73_RS06250 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FQV73_RS06255 ENOG4107QQR Sporulation FQV73_RS06260 ENOG4105S1Z Stage IV sporulation protein B FQV73_RS06265 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FQV73_RS06270 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) FQV73_RS06275 ENOG4105DX0 Hemolysin A FQV73_RS06280 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) FQV73_RS06285 ENOG4105CTB Polyprenyl synthetase FQV73_RS06290 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FQV73_RS06295 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FQV73_RS06300 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FQV73_RS06305 ENOG4105M7K Involved in the transcription termination process (By similarity) FQV73_RS06310 ENOG4108ZSR alkaline shock protein FQV73_RS06315 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FQV73_RS06335 ENOG410644B Stage III sporulation protein af FQV73_RS06345 ENOG4105KQ4 Stage iii sporulation protein ad FQV73_RS06350 ENOG4108CQH stage III sporulation protein AC FQV73_RS06355 ENOG4105KR5 Stage iii sporulation protein FQV73_RS06360 ENOG4105CD2 stage iii sporulation protein aa FQV73_RS06370 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FQV73_RS06375 ENOG4105DC7 peptidase M24 FQV73_RS06385 ENOG4105CBJ Metal-dependent enzyme FQV73_RS06405 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FQV73_RS06410 ENOG4105WZW rhodanese family FQV73_RS06415 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor FQV73_RS06425 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) FQV73_RS06430 ENOG4105C0D helicase FQV73_RS06445 ENOG4108IMY Transcriptional regulator FQV73_RS06455 ENOG4105VFR signal peptidase FQV73_RS06515 ENOG4105C37 (CBS) domain FQV73_RS06540 ENOG4105C5X domain protein FQV73_RS06585 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FQV73_RS06600 ENOG41068DG YceG-like family FQV73_RS06605 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FQV73_RS06610 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FQV73_RS06615 ENOG4105E2Z phosphate ABC transporter (Permease FQV73_RS06620 ENOG4105C8U phosphate abc transporter FQV73_RS06625 ENOG4105CVA phosphate FQV73_RS06630 ENOG4107RF6 penicillin-binding protein FQV73_RS06640 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FQV73_RS06645 ENOG4105SXS Protein of unknown function (DUF456) FQV73_RS06660 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) FQV73_RS06665 ENOG41063Y9 FQV73_RS06670 ENOG4108U5J '-nucleotidase FQV73_RS06675 ENOG4105N80 Ferric uptake regulator, Fur family FQV73_RS06680 ENOG4108JYZ YitT family FQV73_RS06685 ENOG41069ZM Protein of unknown function (DUF2624) FQV73_RS06690 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) FQV73_RS06705 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) FQV73_RS06710 ENOG4105EGD dinuclear metal center protein, YbgI family FQV73_RS06725 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FQV73_RS06730 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FQV73_RS06735 ENOG4108UPT UPF0178 protein FQV73_RS06740 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) FQV73_RS06750 ENOG4105C38 Glycyl-tRNA synthetase beta subunit FQV73_RS06755 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit FQV73_RS06760 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) FQV73_RS06770 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FQV73_RS06775 ENOG4105KG3 cytidine deaminase FQV73_RS06780 ENOG4107YR5 Diacylglycerol kinase FQV73_RS06785 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) FQV73_RS06790 ENOG4105CTJ Metal Dependent Phosphohydrolase FQV73_RS06795 ENOG4105C9A Phoh family FQV73_RS06800 ENOG4105EI1 sporulation protein yqfd FQV73_RS06805 ENOG41068P3 sporulation protein YqfC FQV73_RS06815 ENOG4105DI5 UPF0365 protein FQV73_RS06820 ENOG4105F7J membrane-bound serine protease FQV73_RS06825 ENOG4105KTH gatB Yqey FQV73_RS06840 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FQV73_RS06845 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FQV73_RS06850 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) FQV73_RS06855 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FQV73_RS06860 ENOG4105CFG Acts as a chaperone (By similarity) FQV73_RS06865 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FQV73_RS06870 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) FQV73_RS06875 ENOG4105CSA Coproporphyrinogen iii oxidase FQV73_RS06880 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) FQV73_RS06890 ENOG4108ZRV stage ii sporulation protein p FQV73_RS06895 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) FQV73_RS06900 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) FQV73_RS06905 ENOG4105TQK DNA polymerase iii, delta' subunit FQV73_RS06920 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FQV73_RS06925 ENOG4108UK2 deaminase FQV73_RS06930 ENOG4105KQC Competence protein FQV73_RS06940 ENOG4108D32 Methyltransferase FQV73_RS06950 ENOG4108WF2 Metal Dependent Phosphohydrolase FQV73_RS06955 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) FQV73_RS06960 ENOG410812S Rna-binding protein FQV73_RS06965 ENOG4105E2X shikimate dehydrogenase FQV73_RS06970 ENOG4105CQW ribosome biogenesis GTPase YqeH FQV73_RS06975 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FQV73_RS06995 ENOG41080BT SNARE associated Golgi FQV73_RS07005 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FQV73_RS07020 ENOG41086D8 Transcriptional regulator FQV73_RS07025 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FQV73_RS07035 ENOG4108J8C transporter major facilitator family protein FQV73_RS07045 ENOG4108U7W acetyltransferase FQV73_RS07060 ENOG4108HCJ Hydrolase FQV73_RS07065 ENOG4108HCJ Hydrolase FQV73_RS07075 ENOG4105DG6 mannose-6-phosphate isomerase FQV73_RS07080 ENOG4105DM4 PTS System FQV73_RS07095 ENOG4108Z66 YbaK ebsC protein FQV73_RS07100 ENOG4107RSM transcriptional regulator FQV73_RS07105 ENOG4105D94 Major Facilitator Superfamily FQV73_RS07110 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FQV73_RS07115 ENOG41082JN Transcriptional regulator FQV73_RS07135 ENOG4105TMB Formate nitrite transporter FQV73_RS07140 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FQV73_RS07145 ENOG4108JB9 formate dehydrogenase FQV73_RS07160 ENOG4105C28 cystathionine FQV73_RS07190 ENOG4107XRG penicillin-binding protein FQV73_RS07195 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FQV73_RS07205 ENOG4105CFP Peptidase U32 FQV73_RS07210 ENOG4105XYU peptidase (U32 family) FQV73_RS07220 ENOG4105HHA aminodeoxychorismate lyase FQV73_RS07230 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) FQV73_RS07235 ENOG4105VBH UPF0297 protein FQV73_RS07240 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FQV73_RS07245 ENOG4105C02 permease FQV73_RS07250 ENOG4105CDA abc transporter atp-binding protein FQV73_RS07255 ENOG4105CT1 (ABC) transporter FQV73_RS07260 ENOG4105EAD ABC transporter FQV73_RS07265 ENOG4105DRP amino acid AbC transporter FQV73_RS07275 ENOG41060CR FQV73_RS07285 ENOG4105C7H Helicase, RecD TraA family FQV73_RS07295 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FQV73_RS07300 ENOG4105C3J Cysteine desulfurase FQV73_RS07310 ENOG4105D1H recombination factor protein RarA FQV73_RS07315 ENOG4105CUZ uba thif-type nad fad binding protein FQV73_RS07325 ENOG4105C9M aspartyl-trna synthetase FQV73_RS07330 ENOG4105CUT histidyl-tRNA synthetase FQV73_RS07340 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FQV73_RS07345 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) FQV73_RS07350 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FQV73_RS07360 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FQV73_RS07365 ENOG41067VP Protein of unknown function (DUF1049) FQV73_RS07370 ENOG4105NCW Trka-c domain protein FQV73_RS07375 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FQV73_RS07385 ENOG4105CKP Polysaccharide Biosynthesis Protein FQV73_RS07390 ENOG4108QG2 Membrane FQV73_RS07395 ENOG4105NAP FQV73_RS07400 ENOG4105VIE preprotein translocase, subunit YajC FQV73_RS07405 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) FQV73_RS07410 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) FQV73_RS07415 ENOG41061AI Protein of unknown function (DUF2905) FQV73_RS07420 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) FQV73_RS07425 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) FQV73_RS07445 ENOG4106678 morphogenetic protein associated with SpoVID FQV73_RS07450 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FQV73_RS07455 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FQV73_RS07460 ENOG4108IYU L-aspartate oxidase FQV73_RS07475 ENOG4105CQC Prephenate dehydratase FQV73_RS07485 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FQV73_RS07495 ENOG4105K46 50S ribosomal protein l27 FQV73_RS07500 ENOG4105X36 (ribosomal) protein FQV73_RS07505 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) FQV73_RS07520 ENOG4107QMS site-determining protein FQV73_RS07525 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) FQV73_RS07530 ENOG4105YHC Rod shape-determining protein MreD FQV73_RS07540 ENOG4105DFF Rod shape-determining protein mreb FQV73_RS07545 ENOG4105W5Q DNA repair protein (RadC FQV73_RS07550 ENOG4108Z03 MAF-like protein FQV73_RS07560 ENOG4106A3R peptidase FQV73_RS07565 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FQV73_RS07570 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FQV73_RS07580 ENOG4106AR7 Spore coat protein FQV73_RS07585 ENOG41068KH stage VI sporulation protein D FQV73_RS07590 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase FQV73_RS07595 ENOG4105D52 delta-aminolevulinic acid dehydratase FQV73_RS07605 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) FQV73_RS07615 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) FQV73_RS07625 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) FQV73_RS07630 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FQV73_RS07635 ENOG4108IUQ atp-dependent protease FQV73_RS07640 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) FQV73_RS07645 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FQV73_RS07655 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FQV73_RS07660 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FQV73_RS07665 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FQV73_RS07675 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FQV73_RS07680 ENOG4108ZP8 Acetolactate synthase small subunit FQV73_RS07685 ENOG4105C7K acetolactate synthase FQV73_RS07715 ENOG4107SCJ type I restriction enzyme EcoKI subunit R FQV73_RS07735 ENOG4105M59 Phosphodiesterase, mj0936 family FQV73_RS07740 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FQV73_RS07745 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) FQV73_RS07750 ENOG4108XJQ germination protein FQV73_RS07755 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FQV73_RS07760 ENOG41067TZ transcriptional regulator, MarR family FQV73_RS07765 ENOG4105PFC Transcriptional regulator FQV73_RS07775 ENOG4105E33 succinate dehydrogenase FQV73_RS07785 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FQV73_RS07795 ENOG4105CFH Aspartokinase FQV73_RS07800 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FQV73_RS07805 ENOG4105K63 Thioredoxin FQV73_RS07810 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) FQV73_RS07815 ENOG4105C10 Electron transfer flavoprotein FQV73_RS07820 ENOG4105BZJ Electron transfer flavoprotein FQV73_RS07825 ENOG41060WC Enoyl-CoA hydratase FQV73_RS07830 ENOG4107Z3H Transcriptional regulator, TetR family FQV73_RS07835 ENOG4105CEY Amp-dependent synthetase and ligase FQV73_RS07850 ENOG4105C98 muts2 protein FQV73_RS07855 ENOG4105DCG PHP domain protein FQV73_RS07870 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FQV73_RS07875 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FQV73_RS07880 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) FQV73_RS07885 ENOG4108RWN rrna methyltransferase FQV73_RS07890 ENOG41067MF small acid-soluble spore protein FQV73_RS07900 ENOG4105CQB FAD linked oxidase domain protein FQV73_RS07905 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FQV73_RS07915 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) FQV73_RS07920 ENOG4105DRS transport system, permease FQV73_RS07935 ENOG4108MDK Dehydrogenase FQV73_RS07945 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FQV73_RS07950 ENOG4105EF1 ribulokinase FQV73_RS07960 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase FQV73_RS07965 ENOG4105CN9 Peptidase m42 family protein FQV73_RS07975 ENOG410696E Membrane FQV73_RS07980 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FQV73_RS07985 ENOG4105VJV 50s ribosomal protein L35 FQV73_RS07990 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FQV73_RS07995 ENOG41067MG lrgb family FQV73_RS08005 ENOG4105DY9 regulatoR FQV73_RS08010 ENOG4108HRK Histidine kinase FQV73_RS08020 ENOG4105C22 threonyL-tRNA synthetase FQV73_RS08025 ENOG4108TDW sporulation protein YtxC FQV73_RS08050 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) FQV73_RS08055 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FQV73_RS08060 ENOG4105KVH Transcriptional regulator FQV73_RS08065 ENOG4105F27 Major Facilitator FQV73_RS08070 ENOG4105CV8 reductase FQV73_RS08075 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FQV73_RS08085 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) FQV73_RS08090 ENOG4105C2M dna polymerase I FQV73_RS08095 ENOG4105BZU Histidine kinase FQV73_RS08100 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FQV73_RS08110 ENOG4108HMX isocitrate dehydrogenase (NADP) FQV73_RS08115 ENOG4105BZN citrate synthase FQV73_RS08120 ENOG4105G7B Protein of unknown function (DUF2992) FQV73_RS08135 ENOG4108REF Sporulation integral membrane protein ytvi FQV73_RS08140 ENOG4105FS0 cytoplasmic membrane protein FQV73_RS08145 ENOG4105CA9 Pyruvate kinase FQV73_RS08150 ENOG4105CTQ phosphohexokinase FQV73_RS08155 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) FQV73_RS08160 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) FQV73_RS08165 ENOG4105C6K Malic enzyme FQV73_RS08170 ENOG4105C0B DNA polymerase III (alpha subunit) FQV73_RS08175 ENOG4105VV2 FQV73_RS08185 ENOG4106EVM FQV73_RS08190 ENOG4105SFS phosphoesterase RecJ domain protein FQV73_RS08205 ENOG4105E8R UPF0173 metal-dependent hydrolase FQV73_RS08215 ENOG4105CH7 arginosuccinase FQV73_RS08220 ENOG4105CDH Citrulline--aspartate ligase FQV73_RS08225 ENOG4105EPU Molybdenum cofactor synthesis domain protein FQV73_RS08230 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FQV73_RS08240 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FQV73_RS08245 ENOG4105KBJ sporulation protein ytfj FQV73_RS08255 ENOG4105VK3 rdd domain containing protein FQV73_RS08260 ENOG4105D07 Signal peptide peptidase, SppA FQV73_RS08265 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FQV73_RS08270 ENOG4105EFZ amidohydrolase FQV73_RS08275 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FQV73_RS08285 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) FQV73_RS08310 ENOG4105U5Y Transcriptional regulator FQV73_RS08320 ENOG4105BZU Histidine kinase FQV73_RS08330 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FQV73_RS08335 ENOG4105C26 Dehydrogenase FQV73_RS08345 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FQV73_RS08355 ENOG4108Z0Z intracellular protease Pfpi family FQV73_RS08375 ENOG4108NGU Transcriptional regulator FQV73_RS08390 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FQV73_RS08400 ENOG4105F1V Acetoin utilization protein FQV73_RS08405 ENOG4105W87 Cbs domain FQV73_RS08410 ENOG4105DGU Histone deacetylase FQV73_RS08415 ENOG4105ER2 Ompa motb domain protein FQV73_RS08420 ENOG4107R0U MotA TolQ exbB proton channel FQV73_RS08425 ENOG4105ETE Transcriptional regulator (LacI family FQV73_RS08430 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FQV73_RS08450 ENOG4105DFU Cell wall formation (By similarity) FQV73_RS08460 ENOG4108VDD TRNA binding domain protein FQV73_RS08475 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ FQV73_RS08490 ENOG4105C6K Malic enzyme FQV73_RS08495 ENOG4105C8F Beta-lactamase domain protein FQV73_RS08500 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FQV73_RS08510 ENOG4108V15 phosphotransferase enzyme family FQV73_RS08525 ENOG4107F58 2'-5' rna ligase FQV73_RS08530 ENOG4105C6T cysteine synthase FQV73_RS08535 ENOG4107QSE Dipeptidase FQV73_RS08540 ENOG4105C7N Xanthine uracil vitamin C permease FQV73_RS08555 ENOG4105YW5 deoR family transcriptional regulator FQV73_RS08570 ENOG4105CBX hi0933 family FQV73_RS08575 ENOG4105C94 Transporter FQV73_RS08615 ENOG41085GJ domain protein FQV73_RS08620 ENOG4105C8T Leucyl-tRNA synthetase FQV73_RS08630 ENOG4105BZU Histidine kinase FQV73_RS08635 ENOG410605W Major Facilitator FQV73_RS08650 ENOG4105C19 ABC transporter FQV73_RS08655 ENOG4105EWM Histidine kinase FQV73_RS08665 ENOG4107R34 abc transporter permease protein FQV73_RS08670 ENOG4105C19 ABC transporter FQV73_RS08690 ENOG4105DVE abc transporter atp-binding protein FQV73_RS08695 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FQV73_RS08705 ENOG4105N5T Radical SAM Protein FQV73_RS08720 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FQV73_RS08730 ENOG4105E8V Alpha Beta Hydrolase Fold protein FQV73_RS08735 ENOG4108Z0R Transferase FQV73_RS08740 ENOG4105C85 amino acid FQV73_RS08745 ENOG4105CAQ asparagine synthetase FQV73_RS08750 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP FQV73_RS08755 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase FQV73_RS08770 ENOG4105D2X ABC transporter substrate-binding protein FQV73_RS08780 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FQV73_RS08795 ENOG4108RMU ferritin dps family protein FQV73_RS08810 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) FQV73_RS08815 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) FQV73_RS08820 ENOG4108V2W Carbonate dehydratase FQV73_RS08825 ENOG4105NRA 50s ribosomal protein l31 type b FQV73_RS08845 ENOG4105DTQ mandelate racemase muconate lactonizing FQV73_RS08850 ENOG4105CEY Amp-dependent synthetase and ligase FQV73_RS08855 ENOG4108IPT Naphthoate synthase FQV73_RS08860 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FQV73_RS08865 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) FQV73_RS08870 ENOG4105E4F Isochorismate synthase FQV73_RS09010 ENOG4105N67 Proton-coupled thiamine transporter YuaJ FQV73_RS09015 ENOG4105DZ6 Band 7 protein FQV73_RS09025 ENOG4106DF1 FQV73_RS09030 ENOG4108VNY MOSC domain protein FQV73_RS09035 ENOG4108JB8 alcohol dehydrogenase FQV73_RS09045 ENOG4105TRT Transcriptional regulator FQV73_RS09060 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FQV73_RS09065 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FQV73_RS09085 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FQV73_RS09095 ENOG4105EE0 oxidoreductase FQV73_RS09100 ENOG4108Z0Z intracellular protease Pfpi family FQV73_RS09105 ENOG4105C8Q Methyl-accepting chemotaxis FQV73_RS09110 ENOG4105C8Q Methyl-accepting chemotaxis FQV73_RS09115 ENOG4105C8Q Methyl-accepting chemotaxis FQV73_RS09120 ENOG4105C8Q Methyl-accepting chemotaxis FQV73_RS09135 ENOG4105EA8 2-Nitropropane dioxygenase FQV73_RS09140 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FQV73_RS09150 ENOG4105C37 (CBS) domain FQV73_RS09165 ENOG4107PBV potassium channel FQV73_RS09170 ENOG4107PBV potassium channel FQV73_RS09185 ENOG4107QYV phosphohexose isomerase FQV73_RS09200 ENOG4105CHJ isochorismatase hydrolase FQV73_RS09215 ENOG4107QW4 alcohol dehydrogenase FQV73_RS09220 ENOG4105WG9 Conserved Protein FQV73_RS09230 ENOG4105CHM Aminotransferase FQV73_RS09235 ENOG4108ZB6 transcriptional regulator AsnC family FQV73_RS09240 ENOG4108MUZ hydrolase FQV73_RS09250 ENOG4105C87 Aminotransferase class I and II FQV73_RS09255 ENOG4108HGU Histidine kinase FQV73_RS09260 ENOG4105Y38 Kinase-associated protein B FQV73_RS09275 ENOG4105BZ4 penicillin-binding protein FQV73_RS09280 ENOG4105KIR Thiol-disulfide oxidoreductase dcc FQV73_RS09295 ENOG4108MRH transcriptional regulatory protein FQV73_RS09300 ENOG4105DIH basic membrane FQV73_RS09305 ENOG4108JQ9 ABC transporter FQV73_RS09310 ENOG4105UIB (ABC) transporter FQV73_RS09325 ENOG4105D65 subunit l FQV73_RS09330 ENOG4105HC0 Na H antiporter FQV73_RS09335 ENOG4108ZE9 Monovalent cation H antiporter subunit C FQV73_RS09340 ENOG4108JPZ Monovalent cation H antiporter subunit D FQV73_RS09345 ENOG4105SC1 monovalent cation H antiporter subunit E FQV73_RS09355 ENOG4105KJM monovalent cation h antiporter subunit g FQV73_RS09360 ENOG4105KA0 thioesterase Superfamily protein FQV73_RS09370 ENOG4105BZU Histidine kinase FQV73_RS09395 ENOG4105D58 Diguanylate phosphodiesterase FQV73_RS09400 ENOG4105DAP Nicotinate phosphoribosyltransferase FQV73_RS09425 ENOG4105C02 permease FQV73_RS09440 ENOG410904N short-chain dehydrogenase reductase FQV73_RS09475 ENOG4108K8K Transcriptional regulator FQV73_RS09480 ENOG4105DCF alanine dehydrogenase FQV73_RS09490 ENOG4105WQT MbtH domain protein FQV73_RS09495 ENOG4105CEY Amp-dependent synthetase and ligase FQV73_RS09500 ENOG4105WQI isochorismatase FQV73_RS09505 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FQV73_RS09510 ENOG4105E4F Isochorismate synthase FQV73_RS09515 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FQV73_RS09520 ENOG4105NIV Esterase FQV73_RS09540 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) FQV73_RS09550 ENOG41069ER domain protein FQV73_RS09565 ENOG4105CEP NADH dehydrogenase FQV73_RS09580 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) FQV73_RS09595 ENOG4105CJ1 ABC, transporter FQV73_RS09620 ENOG4108VHC Short-chain dehydrogenase reductase Sdr FQV73_RS09625 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FQV73_RS09630 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) FQV73_RS09640 ENOG4105ZKE UPF0349 protein FQV73_RS09655 ENOG41083MR nifu domain-containing protein FQV73_RS09660 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FQV73_RS09665 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) FQV73_RS09670 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) FQV73_RS09675 ENOG4105D6E homoserine dehydrogenase FQV73_RS09685 ENOG4108W5N phosphatidylglycerophosphatase a FQV73_RS09690 ENOG4105D4U had-superfamily hydrolase, subfamily iia FQV73_RS09700 ENOG4105MMD transcriptional regulator FQV73_RS09705 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FQV73_RS09710 ENOG4105FAA peptidase M23 FQV73_RS09715 ENOG4108YTE sporulation protein YunB FQV73_RS09720 ENOG4107R8B 5'-nucleotidase FQV73_RS09730 ENOG4105I3N Conserved Protein FQV73_RS09740 ENOG4105CD3 dihydroorotase FQV73_RS09745 ENOG4105G9B Transcriptional regulator FQV73_RS09765 ENOG4105C5R Aminotransferase FQV73_RS09775 ENOG4108K8S endonuclease I FQV73_RS09780 ENOG4108IJ9 (ABC) transporter FQV73_RS09785 ENOG4105FDP GntR family transcriptional regulator FQV73_RS09790 ENOG4108KPW sugar kinase FQV73_RS09795 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FQV73_RS09800 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component FQV73_RS09805 ENOG4105XN3 extracellular solute-binding protein family 1 FQV73_RS09810 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine FQV73_RS09820 ENOG4105PKS Excinuclease abc c subunit domain protein FQV73_RS09825 ENOG4107VFR oxidoreductase FQV73_RS09840 ENOG41083Q9 chitosanase FQV73_RS09845 ENOG4105DIW FeS assembly protein SUFB FQV73_RS09850 ENOG4108UNV SUF system FeS assembly protein, NifU family FQV73_RS09855 ENOG4105C9B Cysteine desulfurase FQV73_RS09860 ENOG4105JRK feS assembly protein SufD FQV73_RS09865 ENOG4105C3K feS assembly ATPase SufC FQV73_RS09880 ENOG4105D01 (LipO)protein FQV73_RS09885 ENOG4108UMI ABC transporter, permease FQV73_RS09890 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FQV73_RS09915 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) FQV73_RS09920 ENOG41080E8 Transcriptional regulator, Spx MgsR family FQV73_RS09925 ENOG4105C1G acyl-Coa dehydrogenase FQV73_RS09930 ENOG4105CHU acetyl-coa acetyltransferase FQV73_RS09960 ENOG41067TZ transcriptional regulator, MarR family FQV73_RS09965 ENOG4105C0R drug resistance transporter emrb qaca subfamily FQV73_RS09970 ENOG4105C5Q Transcriptional regulator FQV73_RS09990 ENOG4105E0A ABC, transporter FQV73_RS10005 ENOG4105E1F short-chain dehydrogenase reductase FQV73_RS10010 ENOG4105HUF DNA protection during starvation protein FQV73_RS10015 ENOG4105C0H protease FQV73_RS10025 ENOG4105F3H Histidine kinase FQV73_RS10035 ENOG41067SE Tetr family transcriptional regulator FQV73_RS10040 ENOG4105C9Q fumarate hydratase class II FQV73_RS10065 ENOG4105WH1 Two component transcriptional regulator luxr family FQV73_RS10070 ENOG4105ENE Histidine kinase FQV73_RS10085 ENOG41087YS Phage shock protein A FQV73_RS10100 ENOG4108WBT adenosyltransferase FQV73_RS10105 ENOG4105E0A ABC, transporter FQV73_RS10110 ENOG4105EHG Permease protein FQV73_RS10115 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FQV73_RS10120 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FQV73_RS10125 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FQV73_RS10135 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FQV73_RS10145 ENOG4106DF4 Sigma-70, region 4 FQV73_RS10155 ENOG4105F0F Oxalate decarboxylase FQV73_RS10165 ENOG4105E0A ABC, transporter FQV73_RS10170 ENOG4105EHG Permease protein FQV73_RS10175 ENOG4105DQ5 transport system permease protein FQV73_RS10185 ENOG4105JQZ Methyltransferase FQV73_RS10190 ENOG4105D5Q Arginine ornithine antiporter FQV73_RS10200 ENOG4107K5X Membrane-bound metal-dependent hydrolase FQV73_RS10205 ENOG4107QZ2 Sulfatase FQV73_RS10210 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FQV73_RS10215 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FQV73_RS10220 ENOG4105E0C molybdate abc transporter FQV73_RS10225 ENOG4105WH1 Two component transcriptional regulator luxr family FQV73_RS10230 ENOG4105BZU Histidine kinase FQV73_RS10235 ENOG4105CJ1 ABC, transporter FQV73_RS10245 ENOG4108KYE ABC-2 type transporter FQV73_RS10260 ENOG4105EEQ Na H antiporter FQV73_RS10265 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FQV73_RS10270 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FQV73_RS10275 ENOG4105EEM helicase FQV73_RS10280 ENOG4105EN6 Membrane FQV73_RS10295 ENOG4107ZQN disulfide bond FQV73_RS10300 ENOG4105C59 p-type ATPase FQV73_RS10305 ENOG4105C59 p-type ATPase FQV73_RS10310 ENOG410681U heavy metal transport detoxification protein FQV73_RS10315 ENOG4105VPX protein, conserved in bacteria FQV73_RS10320 ENOG4105D9R oxidoreductase FQV73_RS10325 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FQV73_RS10360 ENOG4105DEN Luciferase family FQV73_RS10365 ENOG4105CDA abc transporter atp-binding protein FQV73_RS10390 ENOG4108XSB acetyltransferase, (GNAT) family FQV73_RS10395 ENOG4108KSA LysR family transcriptional regulator FQV73_RS10400 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FQV73_RS10405 ENOG41067XF inhibitor FQV73_RS10415 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FQV73_RS10420 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FQV73_RS10430 ENOG4105XZU Preprotein translocase, subunit SecG FQV73_RS10450 ENOG4105KVH Transcriptional regulator FQV73_RS10475 ENOG4105DA5 (ABC) transporter FQV73_RS10480 ENOG4105R40 Glycine betaine carnitine choline FQV73_RS10485 ENOG4108HQR Glycine betaine FQV73_RS10490 ENOG4105E90 ABC transporter FQV73_RS10495 ENOG4108IJ8 ABC transporter FQV73_RS10500 ENOG4107HG4 Transcriptional regulator FQV73_RS10505 ENOG4105R40 Glycine betaine carnitine choline FQV73_RS10510 ENOG4108HQR Glycine betaine FQV73_RS10515 ENOG4105E90 ABC transporter FQV73_RS10520 ENOG4108IJ8 ABC transporter FQV73_RS10525 ENOG4107HG4 Transcriptional regulator FQV73_RS10530 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FQV73_RS10540 ENOG4105T65 Membrane-associated protein FQV73_RS10545 ENOG4108W0I acetyltransferase FQV73_RS10560 ENOG4105FJR Lmbe family FQV73_RS10575 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FQV73_RS10580 ENOG4108IAJ Nad-dependent epimerase dehydratase FQV73_RS10585 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FQV73_RS10590 ENOG4107QQG Dehydrogenase FQV73_RS10595 ENOG4105IIU Aminopeptidase FQV73_RS10600 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FQV73_RS10605 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FQV73_RS10610 ENOG4105CP7 Triose-phosphate isomerase FQV73_RS10615 ENOG4105BZA Phosphoglycerate kinase FQV73_RS10620 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FQV73_RS10635 ENOG4105CMD Transcriptional regulator, GntR family FQV73_RS10640 ENOG4105DEN Luciferase family FQV73_RS10650 ENOG4105GZI Transcriptional regulator FQV73_RS10655 ENOG4107RT3 EamA-like transporter family FQV73_RS10665 ENOG4106KNT transcriptional regulator FQV73_RS10670 ENOG4105CMG Carbohydrate kinase FQV73_RS10675 ENOG4105C6Z Gluconate FQV73_RS10685 ENOG4107QR9 Iron-sulfur cluster binding protein FQV73_RS10690 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FQV73_RS10695 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FQV73_RS10700 ENOG4105JXH GntR family transcriptional regulator FQV73_RS10705 ENOG4105DAA L-lactate FQV73_RS10710 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FQV73_RS10720 ENOG4108ZPC Polysaccharide pyruvyl transferase FQV73_RS10725 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FQV73_RS10730 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family FQV73_RS10735 ENOG4105D3Q Sugar transferase FQV73_RS10745 ENOG4105K64 Glycosyl transferase, family 2 FQV73_RS10755 ENOG4107QRS glycosyltransferase group 2 family protein FQV73_RS10760 ENOG41068W6 Capsular polysaccharide biosynthesis protein FQV73_RS10765 ENOG4108KMV Glycosyl transferase (Group 1 FQV73_RS10770 ENOG4105K64 Glycosyl transferase, family 2 FQV73_RS10775 ENOG4108PQP glycosyl transferase group 1 FQV73_RS10785 ENOG4108QV3 biosynthesis protein FQV73_RS10790 ENOG4105HTX biosynthesis protein FQV73_RS10800 ENOG4105EBR Carboxylesterase FQV73_RS10805 ENOG4105NAE bifunctional deaminase-reductase domain protein FQV73_RS10815 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 FQV73_RS10820 ENOG4105PY6 Phenolic acid decarboxylase FQV73_RS10825 ENOG4105NI3 Protein of unknown function (DUF3237) FQV73_RS10870 ENOG4108HKT sucrose-6-phosphate hydrolase FQV73_RS10875 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FQV73_RS10880 ENOG4105ETE Transcriptional regulator (LacI family FQV73_RS10885 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FQV73_RS10890 ENOG4108KAM Transcriptional regulator FQV73_RS10895 ENOG4105C7F AcnD-accessory protein PrpF FQV73_RS10905 ENOG4108URH decarboxylase FQV73_RS10910 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain FQV73_RS10915 ENOG4105CHH sulfate transporter FQV73_RS10920 ENOG4108V2W Carbonate dehydratase FQV73_RS10930 ENOG4105C5I Dehydrogenase FQV73_RS10935 ENOG4105GGE ribonuclease FQV73_RS10940 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FQV73_RS10945 ENOG4105KRI phosphocarrier protein (HPr FQV73_RS10950 ENOG4105CIE May be required for sporulation (By similarity) FQV73_RS10955 ENOG4105CHW UPF0052 protein FQV73_RS10960 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) FQV73_RS10965 ENOG4108Z4K mutator MutT protein FQV73_RS10970 ENOG4105C3M thioredoxin reductase FQV73_RS10985 ENOG4105BZU Histidine kinase FQV73_RS10990 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FQV73_RS11000 ENOG4105BZ1 (ABC) transporter FQV73_RS11005 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FQV73_RS11010 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) FQV73_RS11015 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase FQV73_RS11020 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FQV73_RS11025 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FQV73_RS11030 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FQV73_RS11035 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) FQV73_RS11040 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) FQV73_RS11050 ENOG4108S4C acetyltransferase FQV73_RS11055 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FQV73_RS11065 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) FQV73_RS11070 ENOG4105CE4 GlcNAc 6-P deacetylase FQV73_RS11075 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) FQV73_RS11085 ENOG4105J7D transcriptional regulator FQV73_RS11090 ENOG41088CQ domain protein FQV73_RS11095 ENOG41086DT Membrane protein of unknown function FQV73_RS11100 ENOG41067S9 phage shock protein C, PspC FQV73_RS11105 ENOG4108PY7 FQV73_RS11120 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FQV73_RS11125 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FQV73_RS11140 ENOG4105MKU Transcriptional regulator FQV73_RS11190 ENOG4105CN1 protease FQV73_RS11195 ENOG4108M26 parallel beta-helix repeat protein FQV73_RS11200 ENOG4105CRP Part of the ABC transporter FtsEX involved in FQV73_RS11205 ENOG4105CAK Cell division ATP-binding protein ftsE FQV73_RS11225 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving FQV73_RS11230 ENOG4105MS2 ribosomal subunit Interface protein FQV73_RS11245 ENOG4105MQ3 flagellar protein FliS FQV73_RS11250 ENOG4107RT6 flagellar hook-associated FQV73_RS11255 ENOG4105I03 Flagellin FQV73_RS11260 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FQV73_RS11265 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) FQV73_RS11275 ENOG4105DTJ flagellar hook-associated protein FQV73_RS11280 ENOG4105E1Q flagellar hook-associated protein FQV73_RS11295 ENOG4105RU3 FQV73_RS11300 ENOG41081UC Inherit from COG: Competence protein FQV73_RS11320 ENOG4105WH1 Two component transcriptional regulator luxr family FQV73_RS11325 ENOG4105BZU Histidine kinase FQV73_RS11330 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FQV73_RS11335 ENOG4108KGH TRANSCRIPTIONal FQV73_RS11340 ENOG4105ESV Glycosyl transferase, family 4 FQV73_RS11345 ENOG4107EF8 Glycosyl transferase (Group 1 FQV73_RS11360 ENOG4105QZI O-Antigen Polymerase FQV73_RS11365 ENOG4105C6Y Udp-glucose 6-dehydrogenase FQV73_RS11370 ENOG4107RA4 Glycosyl transferase (Group 1 FQV73_RS11375 ENOG4105PSV Polysaccharide Biosynthesis Protein FQV73_RS11380 ENOG4105D3Q Sugar transferase FQV73_RS11385 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FQV73_RS11390 ENOG4105JFG SpoIID LytB domain protein FQV73_RS11405 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FQV73_RS11410 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FQV73_RS11415 ENOG4105EY8 ABC transporter FQV73_RS11425 ENOG4107SJB teichoic acid biosynthesis FQV73_RS11435 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase FQV73_RS11445 ENOG4107RZX Teichoic acid biosynthesis protein FQV73_RS11455 ENOG4105DG6 mannose-6-phosphate isomerase FQV73_RS11470 ENOG4108NHD germination protein FQV73_RS11475 ENOG4107R8N Glycosyl transferase, family 2 FQV73_RS11480 ENOG4105C54 Major Facilitator superfamily FQV73_RS11485 ENOG4108KGH TRANSCRIPTIONal FQV73_RS11490 ENOG4105J7I hydrolase FQV73_RS11495 ENOG4106UBQ FQV73_RS11500 ENOG4105K4H Nlp p60 protein FQV73_RS11510 ENOG4105PNM synthesis protein FQV73_RS11520 ENOG4105N98 Capsule biosynthesis protein capB FQV73_RS11525 ENOG4105E1K spore germination protein FQV73_RS11540 ENOG4105ETE Transcriptional regulator (LacI family FQV73_RS11545 ENOG4108RVA ribokinase FQV73_RS11550 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) FQV73_RS11555 ENOG4105C2J ABC transporter FQV73_RS11560 ENOG4105CNN ABC, transporter FQV73_RS11565 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FQV73_RS11575 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FQV73_RS11580 ENOG4107FQX Alpha-acetolactate decarboxylase FQV73_RS11590 ENOG4107RSM transcriptional regulator FQV73_RS11605 ENOG4106UIA FQV73_RS11620 ENOG4107XC4 flavin reductase domain protein, FMN-binding FQV73_RS11640 ENOG4105CAH Chromate FQV73_RS11645 ENOG4105FGV Chromate FQV73_RS11655 ENOG4108WS4 fmn reductase FQV73_RS11660 ENOG4107V2S Transcriptional regulator FQV73_RS11665 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) FQV73_RS11695 ENOG4108XI2 Domain of unknown function (DUF1963) FQV73_RS11700 ENOG4105C6Y Udp-glucose 6-dehydrogenase FQV73_RS11705 ENOG4108RB3 Capsular polysaccharide biosynthesis protein FQV73_RS11710 ENOG4107YJ4 chain length determinant protein FQV73_RS11715 ENOG4105HTX biosynthesis protein FQV73_RS11725 ENOG4105KBK Zinc finger, swim domain protein FQV73_RS11730 ENOG4105C0D helicase FQV73_RS11735 ENOG410667J hydrolase FQV73_RS11740 ENOG4105E98 transcriptional regulator DeoR family FQV73_RS11745 ENOG4105Z8H single-stranded DNA-binding protein FQV73_RS11760 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) FQV73_RS11765 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) FQV73_RS11775 ENOG4105CGA flagellar basal-body rod protein FlgG FQV73_RS11785 ENOG4105DFF Rod shape-determining protein mreb FQV73_RS11790 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FQV73_RS11795 ENOG4107MII Sugar-specific transcriptional regulator TrmB FQV73_RS11800 ENOG4105CZM Major Facilitator FQV73_RS11805 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FQV73_RS11810 ENOG41080V3 Major Facilitator superfamily FQV73_RS11815 ENOG4105D3W isochorismatase FQV73_RS11820 ENOG4105BZU Histidine kinase FQV73_RS11830 ENOG4105CNI cell division protein FtsW FQV73_RS11835 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FQV73_RS11845 ENOG4105FRN stage II sporulation protein FQV73_RS11850 ENOG4107TCE N-acetyltransferase FQV73_RS11865 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FQV73_RS11870 ENOG4106BRK FQV73_RS11875 ENOG4107T94 Endo-14-beta-xylanase FQV73_RS11885 ENOG4108Z40 Transcriptional regulator FQV73_RS11890 ENOG4105CQM Urea amidohydrolase subunit alpha FQV73_RS11895 ENOG4105KI2 Urea amidohydrolase subunit beta FQV73_RS11900 ENOG4108YZ9 Urea amidohydrolase subunit gamma FQV73_RS11920 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FQV73_RS11925 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FQV73_RS11935 ENOG4108TF4 von Willebrand factor, type A FQV73_RS11950 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FQV73_RS11960 ENOG4106778 Protein of unknown function (DUF1146) FQV73_RS11970 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FQV73_RS11975 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) FQV73_RS11980 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) FQV73_RS11985 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) FQV73_RS11990 ENOG4107YZM F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FQV73_RS12005 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) FQV73_RS12015 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) FQV73_RS12020 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FQV73_RS12025 ENOG4108UIC UPF0340 protein FQV73_RS12030 ENOG4108YZG isomerase FQV73_RS12035 ENOG4107WAU Protein tyrosine phosphatase FQV73_RS12040 ENOG410815N Probably functions as a manganese efflux pump (By similarity) FQV73_RS12045 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FQV73_RS12055 ENOG4108ZXQ stage ii sporulation protein r FQV73_RS12070 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FQV73_RS12075 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FQV73_RS12080 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FQV73_RS12090 ENOG4107TT2 Auxin Efflux Carrier FQV73_RS12095 ENOG4105C6K Malic enzyme FQV73_RS12100 ENOG4107104 thymidine kinase FQV73_RS12110 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FQV73_RS12115 ENOG4105CBT Fructose-1,6-bisphosphatase FQV73_RS12120 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FQV73_RS12130 ENOG4105D2N Aldolase FQV73_RS12135 ENOG410812K response regulator receiver protein FQV73_RS12145 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FQV73_RS12155 ENOG4105DF6 Fe-S oxidoreductase FQV73_RS12165 ENOG4105E5J UV damage endonuclease FQV73_RS12175 ENOG4105BZ1 (ABC) transporter FQV73_RS12180 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FQV73_RS12195 ENOG4105R3A Nitrate reductase FQV73_RS12200 ENOG4108IUE nitrate reductase beta subunit FQV73_RS12220 ENOG4107V6Q Cyclic nucleotide-binding domain FQV73_RS12230 ENOG4105C75 arginyL-tRNA synthetase FQV73_RS12235 ENOG410684U Domain of unknown function (DUF1934) FQV73_RS12240 ENOG4107JM4 Tetratricopeptide repeat FQV73_RS12285 ENOG4105CYW agmatinase FQV73_RS12290 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) FQV73_RS12295 ENOG4105BZ4 penicillin-binding protein FQV73_RS12305 ENOG4108XFG YwhD family FQV73_RS12310 ENOG4108Z4T Peptidase M50 FQV73_RS12315 ENOG41069HH 4-oxalocrotonate tautomerase FQV73_RS12320 ENOG41067TZ transcriptional regulator, MarR family FQV73_RS12325 ENOG4105CUB amino acid FQV73_RS12335 ENOG4105DCI Phosphohydrolase FQV73_RS12345 ENOG4108VCI transcription factor, rsfa family FQV73_RS12350 ENOG4105K7K Transcriptional regulator FQV73_RS12365 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) FQV73_RS12370 ENOG4105DUM transcriptional regulator, lysR family FQV73_RS12375 ENOG4105HMI Membrane FQV73_RS12380 ENOG4108IJ2 phosphate acetyltransferase FQV73_RS12385 ENOG4107JTW chlorite dismutase FQV73_RS12395 ENOG4105CHM Aminotransferase FQV73_RS12425 ENOG4105FCW Major Facilitator superfamily FQV73_RS12430 ENOG4105C2C drug resistance transporter, Bcr CflA FQV73_RS12445 ENOG4105C26 Dehydrogenase FQV73_RS12450 ENOG4105D82 Glutamate dehydrogenase FQV73_RS12460 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase FQV73_RS12465 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FQV73_RS12470 ENOG4105C1B dTDP-glucose 4-6-dehydratase FQV73_RS12475 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FQV73_RS12480 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG FQV73_RS12485 ENOG4107TY6 Acylneuraminate cytidylyltransferase FQV73_RS12495 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD FQV73_RS12500 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FQV73_RS12535 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) FQV73_RS12540 ENOG4108RJ9 Glycosyl transferase, family 2 FQV73_RS12560 ENOG4105DWF phosphomethylpyrimidine kinase FQV73_RS12575 ENOG4105C5Y PTS System FQV73_RS12590 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FQV73_RS12595 ENOG4105DEN Luciferase family FQV73_RS12600 ENOG4108DBC nitroreductase FQV73_RS12605 ENOG4105C19 ABC transporter FQV73_RS12630 ENOG4105I4A GCN5-related N-acetyltransferase FQV73_RS12650 ENOG4105BZ9 Cytochrome C oxidase, subunit I FQV73_RS12655 ENOG4105E2S oxidase) subunit II FQV73_RS12660 ENOG4107BMA Transglycosylase associated protein FQV73_RS12675 ENOG4105WH5 Teichoic acid glycosylation protein FQV73_RS12700 ENOG4107ZXU DSBA oxidoreductase FQV73_RS12705 ENOG4105DBE peroxidase FQV73_RS12710 ENOG410650H (LipO)protein FQV73_RS12715 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FQV73_RS12720 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase FQV73_RS12725 ENOG4105CMU LysR family (Transcriptional regulator FQV73_RS12730 ENOG4105VAW lrga family FQV73_RS12735 ENOG41067MG lrgb family FQV73_RS12745 ENOG4107TXC Transcriptional regulator FQV73_RS12750 ENOG4105DR4 Methyltransferase FQV73_RS12760 ENOG4105CK1 PTS System FQV73_RS12765 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin FQV73_RS12770 ENOG4105X1N Glycosyl transferase family 8 FQV73_RS12780 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FQV73_RS12790 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) FQV73_RS12795 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FQV73_RS12800 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) FQV73_RS12805 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FQV73_RS12810 ENOG4105CM2 brancheD-chain amino acid aminotransferase FQV73_RS12815 ENOG4105F8D glycoside hydrolase family 4 FQV73_RS12820 ENOG4105VCP PTS System FQV73_RS12825 ENOG4105CK1 PTS System FQV73_RS12830 ENOG4105VZJ PTS System FQV73_RS12835 ENOG4105EMD TRANSCRIPTIONal FQV73_RS12845 ENOG4105DQ5 transport system permease protein FQV73_RS12850 ENOG4105EHG Permease protein FQV73_RS12860 ENOG41082YX Transcriptional regulator, arsr family FQV73_RS12865 ENOG4107R5R arsenical pump membrane protein FQV73_RS12870 ENOG4105VZJ PTS System FQV73_RS12875 ENOG4105VCP PTS System FQV73_RS12880 ENOG4105CK1 PTS System FQV73_RS12885 ENOG4105CS2 ec 3.2.1.21 FQV73_RS12890 ENOG4105EVU fructokinase FQV73_RS12895 ENOG4105DG6 mannose-6-phosphate isomerase FQV73_RS12905 ENOG4105CH6 catalase FQV73_RS12910 ENOG4107QHE Choloylglycine hydrolase FQV73_RS12915 ENOG4105ETS cytosine purines uracil thiamine allantoin FQV73_RS12920 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FQV73_RS12925 ENOG4108JJ8 (ABC) transporter FQV73_RS12930 ENOG4108JJ9 ABC, transporter FQV73_RS12935 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FQV73_RS12940 ENOG4105C4M (Ubiquinol oxidase) subunit I FQV73_RS12945 ENOG4105D2K citrate carrier protein FQV73_RS12950 ENOG4107BJW polysaccharide deacetylase FQV73_RS12965 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FQV73_RS12975 ENOG4105CMR udp-glucose 4-epimerase FQV73_RS12980 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FQV73_RS13000 ENOG4105DHI Methyltransferase FQV73_RS13025 ENOG4105CH6 catalase FQV73_RS13030 ENOG4105D4T Citrate transporter FQV73_RS13045 ENOG4105DEU major facilitator superfamily FQV73_RS13050 ENOG4105C1J atp-dependent rna helicase FQV73_RS13115 ENOG4108NR7 pectate lyase FQV73_RS13125 ENOG4107YZX Universal stress protein FQV73_RS13130 ENOG4105CS2 ec 3.2.1.21 FQV73_RS13135 ENOG4105C5Y PTS System FQV73_RS13150 ENOG4106Z5D Glycoside Hydrolase Family 43 FQV73_RS13160 ENOG4105C84 Histidine ammonia-lyase FQV73_RS13165 ENOG4105CGP Urocanate hydratase FQV73_RS13170 ENOG4105CI2 imidazolone-5-propionate hydrolase FQV73_RS13175 ENOG4107W25 arginase agmatinase formiminoglutamase FQV73_RS13185 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FQV73_RS13190 ENOG4105D9N nucleoside FQV73_RS13195 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) FQV73_RS13200 ENOG4107RHR regulatoR FQV73_RS13205 ENOG410667J hydrolase FQV73_RS13235 ENOG4108V5C ABC transporter FQV73_RS13270 ENOG4105WZ4 isomerase FQV73_RS13275 ENOG4105F0H myo-inositol catabolism protein FQV73_RS13280 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FQV73_RS13290 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) FQV73_RS13300 ENOG4105EDK PfkB domain protein FQV73_RS13310 ENOG4105C26 Dehydrogenase FQV73_RS13320 ENOG4105CPC Aldo Keto reductase FQV73_RS13325 ENOG4107QNK )-transporter FQV73_RS13330 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FQV73_RS13340 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FQV73_RS13345 ENOG4108S01 response regulator FQV73_RS13350 ENOG4108ZGX Histidine kinase FQV73_RS13355 ENOG4105ECK Fatty Acid Desaturase FQV73_RS13360 ENOG4105ST3 Transcriptional regulator FQV73_RS13365 ENOG4105C26 Dehydrogenase FQV73_RS13370 ENOG4108ITS PQQ enzyme repeat FQV73_RS13380 ENOG4105WAB arsR family transcriptional regulator FQV73_RS13385 ENOG4105F27 Major Facilitator FQV73_RS13390 ENOG41085PJ rdd domain containing protein FQV73_RS13400 ENOG4105D3R alkyl hydroperoxide reductase FQV73_RS13405 ENOG4108JU3 Alkyl hydroperoxide reductase FQV73_RS13410 ENOG4105C85 amino acid FQV73_RS13415 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 FQV73_RS13420 ENOG4108XHQ (2Fe-2S)-binding domain protein FQV73_RS13440 ENOG4105XRQ Xanthine dehydrogenase accessory factor FQV73_RS13460 ENOG4107QJE Chromosome Partitioning Protein FQV73_RS13465 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) FQV73_RS13485 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) FQV73_RS13490 ENOG4105CPC Aldo Keto reductase FQV73_RS13495 ENOG4105WQG acetyltransferase FQV73_RS13505 ENOG41066UZ arginase EC 3.5.3.1 FQV73_RS13510 ENOG4108IQI permease FQV73_RS13515 ENOG4105C8Y Acetylornithine aminotransferase FQV73_RS13525 ENOG41082BM Transcriptional regulator, arsr family FQV73_RS13530 ENOG4108JUB Transcriptional regulator FQV73_RS13540 ENOG4105C5H ABC transporter FQV73_RS13555 ENOG4105D06 uba thif-type nad fad binding protein FQV73_RS13560 ENOG4105BZU Histidine kinase FQV73_RS13570 ENOG4105C0H protease FQV73_RS13575 ENOG4105Q2H domain protein FQV73_RS13590 ENOG4105BZU Histidine kinase FQV73_RS13595 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FQV73_RS13620 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis FQV73_RS13625 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FQV73_RS13630 ENOG4105CDU Replicative dna helicase FQV73_RS13650 ENOG4107QPH glycogen) synthase FQV73_RS13660 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR FQV73_RS13665 ENOG4105CPK Glycosyl transferase (Group 1 FQV73_RS13685 ENOG4105BZR domain protein FQV73_RS13690 ENOG4108XMW Membrane FQV73_RS13705 ENOG4105KVH Transcriptional regulator FQV73_RS13710 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase FQV73_RS13715 ENOG4108UZ3 Transporter FQV73_RS13720 ENOG4105EDQ levansucrase EC 2.4.1.10 FQV73_RS13725 ENOG4108HKT sucrose-6-phosphate hydrolase FQV73_RS13730 ENOG4107XBN GntR Family Transcriptional Regulator FQV73_RS13750 ENOG4108TVJ Nitroreductase FQV73_RS13755 ENOG4105FS7 Transcriptional regulator FQV73_RS13765 ENOG4108U05 Transcriptional regulator FQV73_RS13780 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FQV73_RS13785 ENOG4105CMU LysR family (Transcriptional regulator FQV73_RS13790 ENOG4105DTD Dehydrogenase FQV73_RS13800 ENOG4107Y9U Membrane FQV73_RS13820 ENOG4105C7Z Conserved Protein FQV73_RS13825 ENOG4107FCW Abortive infection protein FQV73_RS13835 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FQV73_RS13845 ENOG4105CGK Exodeoxyribonuclease III FQV73_RS13850 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FQV73_RS13860 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FQV73_RS13865 ENOG4108UUM single-stranded DNA-binding protein FQV73_RS13870 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) FQV73_RS13875 ENOG4105C3G gtp-binding protein FQV73_RS13880 ENOG4108J2R molybdopterin oxidoreductase FQV73_RS13885 ENOG4105VDK protein, conserved in bacteria FQV73_RS13900 ENOG4108ZDA Sporulation protein YyaC FQV73_RS13905 ENOG4105FA0 parb-like partition protein FQV73_RS13910 ENOG4107QJE Chromosome Partitioning Protein FQV73_RS13925 ENOG4105CWE NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) FQV73_RS13930 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FQV73_RS13945 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) FQV73_RS13955 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) FQV73_RS13960 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FQV73_RS13965 ENOG410848D S4 domain protein YaaA FQV73_RS13970 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FQV73_RS13980 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FQV73_RS13985 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FQV73_RS13995 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FQV73_RS14005 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) FQV73_RS14010 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) FQV73_RS14015 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) FQV73_RS14020 ENOG4105BZW Glycerate kinase FQV73_RS14030 ENOG4105ZMH deoxynucleoside kinase FQV73_RS14040 ENOG4105VRS hydrolase family 18 FQV73_RS14045 ENOG4105GTG Isochorismatase FQV73_RS14050 ENOG4108Z6B deaminase FQV73_RS14060 ENOG4105C6E dna polymerase iii FQV73_RS14065 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) FQV73_RS14070 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FQV73_RS14080 ENOG41067KS pro-sigma K processing FQV73_RS14110 ENOG4105CDW Resistance protein FQV73_RS14115 ENOG4105CXN decarboxylase FQV73_RS14120 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) FQV73_RS14125 ENOG4105X0R protein from nitrogen regulatory protein P-II FQV73_RS14130 ENOG4105XVJ Protein of unknown function (DUF327) FQV73_RS14135 ENOG4105FA2 dna polymerase iii FQV73_RS14140 ENOG4105MA4 psp1 domain protein FQV73_RS14150 ENOG41060K3 Methyltransferase FQV73_RS14155 ENOG4105VC4 domain protein FQV73_RS14160 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FQV73_RS14165 ENOG4105KRN Transcriptional regulator, abrb family FQV73_RS14170 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FQV73_RS14175 ENOG4105F8V Hydrolase, tatD family FQV73_RS14180 ENOG41069ER domain protein FQV73_RS14190 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FQV73_RS14195 ENOG4105XFA sporulation peptidase YabG FQV73_RS14200 ENOG4105W42 Veg protein FQV73_RS14205 ENOG4105XEW small acid-soluble spore protein FQV73_RS14210 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FQV73_RS14215 ENOG4105DFT pur operon repressor FQV73_RS14220 ENOG4105KME endoribonuclease L-psp FQV73_RS14225 ENOG4105K4W Could be involved in septation (By similarity) FQV73_RS14230 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) FQV73_RS14235 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FQV73_RS14240 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) FQV73_RS14255 ENOG4108JA2 transcriptioN-repair coupling factor FQV73_RS14260 ENOG4108M14 stage v sporulation protein t FQV73_RS14270 ENOG4108IY2 MazG family FQV73_RS14275 ENOG41082I2 s4 domain protein FQV73_RS14280 ENOG4105VYY sporulation protein yabp FQV73_RS14295 ENOG41060GV RNA binding s1 domain protein FQV73_RS14325 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FQV73_RS14330 ENOG4108UGV hypoxanthine phosphoribosyltransferase FQV73_RS14335 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FQV73_RS14340 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) FQV73_RS14345 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FQV73_RS14350 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase FQV73_RS14355 ENOG4105C6T cysteine synthase FQV73_RS14360 ENOG4105CRQ synthase (Component I) FQV73_RS14365 ENOG4105DDQ anthranilate synthase FQV73_RS14370 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FQV73_RS14375 ENOG4105EEI dihydropteroate synthase FQV73_RS14380 ENOG4105KRF dihydroneopterin aldolase FQV73_RS14385 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FQV73_RS14395 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FQV73_RS14400 ENOG4105CRK lysyL-tRNA synthetase FQV73_RS14485 ENOG4108Z0C Uvrb UvrC protein FQV73_RS14490 ENOG41066A3 ATP guanido phosphotransferase FQV73_RS14500 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FQV73_RS14505 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) FQV73_RS14510 ENOG4105CTP PilT protein domain protein FQV73_RS14515 ENOG4108QHG Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) FQV73_RS14520 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FQV73_RS14525 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FQV73_RS14530 ENOG4105D7W serine acetyltransferase FQV73_RS14540 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) FQV73_RS14545 ENOG4105C2N RNA methyltransferase TrmH family group 3 FQV73_RS14550 ENOG4105M0M Tetracycline resistance protein FQV73_RS14570 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FQV73_RS14585 ENOG4108VZM 50s ribosomal protein L10 FQV73_RS14595 ENOG4107Y49 methyltransferase FQV73_RS14600 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FQV73_RS14605 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FQV73_RS14610 ENOG4105XPM ribosomal protein FQV73_RS14615 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FQV73_RS14620 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FQV73_RS14625 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FQV73_RS14630 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FQV73_RS14635 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FQV73_RS14640 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) FQV73_RS14645 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FQV73_RS14650 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FQV73_RS14660 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FQV73_RS14675 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FQV73_RS14690 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FQV73_RS14705 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits FQV73_RS14715 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FQV73_RS14720 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) FQV73_RS14725 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FQV73_RS14730 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FQV73_RS14740 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FQV73_RS14745 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FQV73_RS14750 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FQV73_RS14755 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FQV73_RS14770 ENOG41067V7 50S ribosomal protein L36 FQV73_RS14775 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FQV73_RS14780 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FQV73_RS14785 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FQV73_RS14790 ENOG4108ZT0 50S ribosomal protein l17 FQV73_RS14795 ENOG4108JJB ABC transporter FQV73_RS14800 ENOG4108JJB ABC transporter FQV73_RS14805 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FQV73_RS14810 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FQV73_RS14815 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) FQV73_RS14820 ENOG4108UJD 30S ribosomal protein S9 FQV73_RS14825 ENOG4108I0C methyltransferase FQV73_RS14845 ENOG4105D1F ATP-binding protein FQV73_RS14860 ENOG4108NMV polysaccharide deacetylase FQV73_RS14970 ENOG4108JPW Aminotransferase FQV73_RS14980 ENOG4105CPQ Dehydrogenase FQV73_RS14985 ENOG4105CHH sulfate transporter FQV73_RS14995 ENOG4108SA1 esterase FQV73_RS15015 ENOG410874W AraC family transcriptional regulator FQV73_RS15020 ENOG4105EHZ conserved protein UCP016719 FQV73_RS15025 ENOG4105D17 glycoside hydrolase, family 3 domain protein FQV73_RS15040 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FQV73_RS15050 ENOG4105EWC Purine nucleoside phosphorylase FQV73_RS15080 ENOG4105EMN RNA polymerase sigma factor FQV73_RS15090 ENOG4105C8B TIGR00159 family FQV73_RS15095 ENOG4107U5W ybbr family FQV73_RS15100 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) FQV73_RS15125 ENOG41067MG lrgb family FQV73_RS15135 ENOG41061AU MarR family Transcriptional regulator FQV73_RS15150 ENOG4105BZU Histidine kinase FQV73_RS15155 ENOG4105WH1 Two component transcriptional regulator luxr family FQV73_RS15160 ENOG4105CJ1 ABC, transporter FQV73_RS15185 ENOG4106DDH Sporulation-specific SASP protein FQV73_RS15200 ENOG4107QTZ amino acid FQV73_RS15205 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FQV73_RS15210 ENOG4105CXY transporter FQV73_RS15245 ENOG4107SCQ Iron-containing alcohol dehydrogenase FQV73_RS15250 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR FQV73_RS15255 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FQV73_RS15260 ENOG4107ZTW SNARE associated Golgi FQV73_RS15275 ENOG4105C72 UPF0176 protein FQV73_RS15285 ENOG4105CM2 brancheD-chain amino acid aminotransferase FQV73_RS15290 ENOG4108IQI permease FQV73_RS15295 ENOG4108J5H Homocysteine s-methyltransferase FQV73_RS15305 ENOG4105CSV Glutaminase FQV73_RS15330 ENOG41076HS cation diffusion facilitator family transporter FQV73_RS15335 ENOG4108TVJ Nitroreductase FQV73_RS15340 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FQV73_RS15345 ENOG4108VGI doxx family FQV73_RS15350 ENOG4105XXY Thioredoxin FQV73_RS15370 ENOG4105DGI Alkaline phosphatase FQV73_RS15375 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FQV73_RS15380 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FQV73_RS15385 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) FQV73_RS15390 ENOG4107EPV Aminotransferase class V FQV73_RS15395 ENOG4105C0R drug resistance transporter emrb qaca subfamily FQV73_RS15400 ENOG4105J7D transcriptional regulator FQV73_RS15405 ENOG4107RB3 L-asparaginase FQV73_RS15410 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold FQV73_RS15415 ENOG41060AI SEC-C motif FQV73_RS15420 ENOG4107SET aldo keto reductase FQV73_RS15450 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FQV73_RS15460 ENOG4105DSE periplasmic solute binding protein FQV73_RS15465 ENOG4105DIK (ABC) transporter FQV73_RS15475 ENOG4105DEN Luciferase family FQV73_RS15480 ENOG4108N0M stress protein FQV73_RS15485 ENOG4106FN3 tellurium resistance protein FQV73_RS15490 ENOG4106FN3 tellurium resistance protein FQV73_RS15495 ENOG4107TS3 membrane protein, TerC FQV73_RS15500 ENOG4108TTB tellurium resistance protein FQV73_RS15510 ENOG41079KZ Major Facilitator Superfamily FQV73_RS15515 ENOG4108IJ7 Glycine betaine FQV73_RS15520 ENOG4107SQ8 Glycine betaine FQV73_RS15550 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FQV73_RS15580 ENOG4105EIG urea carboxylase-associated protein 1 FQV73_RS15585 ENOG4107RA1 nh(3)-dependent nad( ) synthetase FQV73_RS15595 ENOG4105I1F Resistance protein FQV73_RS15600 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) FQV73_RS15605 ENOG4105DJB Major Facilitator Superfamily FQV73_RS15610 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) FQV73_RS15615 ENOG4105I82 acetyl xylan esterase FQV73_RS15620 ENOG410756H nucleotidyltransferase FQV73_RS15630 ENOG4105C26 Dehydrogenase FQV73_RS15635 ENOG4105CK7 Sodium proline symporter FQV73_RS15640 ENOG4107YHD transcriptional regulator FQV73_RS15645 ENOG4105CAY ferredoxin--nadp reductase FQV73_RS15650 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FQV73_RS15655 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FQV73_RS15660 ENOG4108IFG nitrite reductase, (NAD(P)H) FQV73_RS15665 ENOG4105CKI cobalamin synthesis protein FQV73_RS15670 ENOG4105E2A Dehydrogenase FQV73_RS15675 ENOG4105HHM rdd domain containing protein FQV73_RS15685 ENOG4105CS2 ec 3.2.1.21 FQV73_RS15705 ENOG41080HJ 6-phospho 3-hexuloisomerase FQV73_RS15710 ENOG4108VA3 3-hexulose-6-phosphate synthase FQV73_RS15715 ENOG4105KVH Transcriptional regulator FQV73_RS15720 ENOG4105CEY Amp-dependent synthetase and ligase FQV73_RS15740 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) FQV73_RS15755 ENOG4105CDA abc transporter atp-binding protein FQV73_RS15760 ENOG4105DRP amino acid AbC transporter FQV73_RS15770 ENOG4106P55 Transcriptional regulator FQV73_RS15775 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FQV73_RS15780 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FQV73_RS15785 ENOG41069ZX FQV73_RS15790 ENOG41069ZX FQV73_RS15795 ENOG4105DUX Transporter FQV73_RS15810 ENOG4105E1K spore germination protein FQV73_RS15835 ENOG4105EAB amino acid AbC transporter FQV73_RS15840 ENOG4108HW4 amino acid AbC transporter FQV73_RS15855 ENOG4108PGP mmge prpd family protein FQV73_RS15865 ENOG4107WD8 ABC transporter, permease FQV73_RS15870 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FQV73_RS15875 ENOG4105BZU Histidine kinase FQV73_RS15895 ENOG4105CFH Aspartokinase FQV73_RS15900 ENOG4105DHS permease protein FQV73_RS15905 ENOG4105CM4 permease protein FQV73_RS15910 ENOG4108IPW abc transporter atp-binding protein FQV73_RS15925 ENOG4105R8C Transcriptional regulator FQV73_RS15930 ENOG4108DBC nitroreductase FQV73_RS15935 ENOG41067V3 Antibiotic biosynthesis monooxygenase FQV73_RS15940 ENOG4105YVS arsR family transcriptional regulator FQV73_RS15950 ENOG4108JPW Aminotransferase FQV73_RS15955 ENOG4105C26 Dehydrogenase FQV73_RS15965 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FQV73_RS15970 ENOG4105KTB nuclear export factor GLE1 FQV73_RS15975 ENOG4108T5E Copper resistance protein FQV73_RS15980 ENOG4108ZYE Transcriptional regulator FQV73_RS16000 ENOG4107SQ3 mannitol-1-phosphate 5-dehydrogenase FQV73_RS16020 ENOG4105E7W lamb ycsf family protein FQV73_RS16025 ENOG4105C5A transporter FQV73_RS16030 ENOG4105CFM UPF0317 protein FQV73_RS16035 ENOG4105P4J Allophanate hydrolase, subunit 1 FQV73_RS16045 ENOG4107258 Transcriptional regulator FQV73_RS16050 ENOG4105XJB lipolytic protein G-D-S-L family FQV73_RS16060 ENOG41061CK Antibiotic biosynthesis monooxygenase FQV73_RS16065 ENOG4107RVG penicillin-binding protein FQV73_RS16070 ENOG4107QM2 Aldo Keto reductase FQV73_RS16075 ENOG4105ETD TRANSCRIPTIONal FQV73_RS16085 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FQV73_RS16100 ENOG410606W general stress protein FQV73_RS16110 ENOG4105VCH membrane FQV73_RS16120 ENOG4105C9U ATP-dependent DNA helicase RecQ FQV73_RS16135 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FQV73_RS16140 ENOG4107R8N Glycosyl transferase, family 2 FQV73_RS16150 ENOG4105C0X amino acid FQV73_RS16185 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FQV73_RS16195 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) FQV73_RS16200 ENOG4105RXJ FQV73_RS16205 ENOG4105KPY Small multidrug resistance protein FQV73_RS16210 ENOG4105EU9 FQV73_RS16215 ENOG4105QVS general stress protein FQV73_RS16220 ENOG41082W1 Cupin 2, conserved barrel domain protein FQV73_RS16235 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FQV73_RS16240 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FQV73_RS16245 ENOG4108MRH transcriptional regulatory protein FQV73_RS16250 ENOG4107QJT sodium dicarboxylate symporter FQV73_RS16255 ENOG4106F5Q Membrane FQV73_RS16260 ENOG4105CJ1 ABC, transporter FQV73_RS16275 ENOG4105FDT acyl-CoA dehydrogenase FQV73_RS16295 ENOG4105SZ6 Thioredoxin FQV73_RS16300 ENOG4105CPF Cell wall formation (By similarity) FQV73_RS16305 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FQV73_RS16310 ENOG4105C1J atp-dependent rna helicase FQV73_RS16315 ENOG410905X membrane-flanked domain protein FQV73_RS16320 ENOG4105CKV Membrane FQV73_RS16330 ENOG4107ZSJ Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) FQV73_RS16335 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FQV73_RS16340 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FQV73_RS16350 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FQV73_RS16355 ENOG4107MMM Anti-sigma-factor antagonist FQV73_RS16360 ENOG4105FUA antagonist FQV73_RS16365 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase FQV73_RS16370 ENOG4107SGM protein serine threonine phosphatase FQV73_RS16375 ENOG4105WN5 stage II sporulation protein FQV73_RS16380 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) FQV73_RS16390 ENOG41064BQ Phosphatase FQV73_RS16405 ENOG410906U SprT-like FQV73_RS16450 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FQV73_RS16465 ENOG4105C94 Transporter FQV73_RS16470 ENOG4105CSH Transporter FQV73_RS16485 ENOG4105K56 Transcriptional regulator FQV73_RS16495 ENOG4108ZMQ domain protein FQV73_RS16505 ENOG4105D1H recombination factor protein RarA FQV73_RS16510 ENOG4108Z40 Transcriptional regulator FQV73_RS16515 ENOG4108RYK Nad-dependent epimerase dehydratase FQV73_RS16520 ENOG4105VEQ Cold shock protein FQV73_RS16530 ENOG4105XTG Pfam:DUF156 FQV73_RS16535 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase FQV73_RS16540 ENOG4105C72 UPF0176 protein FQV73_RS16545 ENOG4105VFE sira family FQV73_RS16550 ENOG4107TPS domain protein FQV73_RS16555 ENOG4105VFE sira family FQV73_RS16560 ENOG41087NI Sulfite exporter TauE/SafE FQV73_RS16580 ENOG4105IRW patatin-like phospholipase family protein FQV73_RS16590 ENOG4107RCH Diaminopropionate ammonia-lyase FQV73_RS16595 ENOG4108WYP Transcriptional regulator FQV73_RS16600 ENOG4105KME endoribonuclease L-psp FQV73_RS16605 ENOG4105C44 Serine transporter FQV73_RS16610 ENOG4105CH2 amidohydrolase FQV73_RS16615 ENOG4108MCI Transcriptional regulator, ARAC family FQV73_RS16620 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FQV73_RS16625 ENOG4107U9B transcriptional regulator FQV73_RS16630 ENOG4105DXI Major Facilitator superfamily FQV73_RS16650 ENOG4105DNP FAD linked oxidase domain protein FQV73_RS16660 ENOG4105PGM cation diffusion facilitator family transporter FQV73_RS16665 ENOG4105H3G oxidoreductase FQV73_RS16680 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FQV73_RS16705 ENOG4105DQ4 alcohol dehydrogenase FQV73_RS16710 ENOG4105VUF Transcriptional regulator FQV73_RS16720 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FQV73_RS16735 ENOG4105EQ0 Major Facilitator superfamily FQV73_RS16740 ENOG4108JGH Tetr family transcriptional regulator FQV73_RS16755 ENOG4105E2A Dehydrogenase FQV73_RS16760 ENOG4105PGS Spore coat protein FQV73_RS16770 ENOG4105ENE Histidine kinase FQV73_RS16775 ENOG4108VB1 regulatoR FQV73_RS16780 ENOG4105EYF MMPL domain protein FQV73_RS16800 ENOG4108JYZ YitT family FQV73_RS16810 ENOG4105C2C drug resistance transporter, Bcr CflA FQV73_RS16815 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FQV73_RS16835 ENOG41090E6 transcriptional regulator MERR family FQV73_RS16850 ENOG4105F2W methyltransferase FQV73_RS16855 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FQV73_RS16860 ENOG4105DRR Transcriptional regulator, GntR family FQV73_RS16880 ENOG4105FQP Beta-lactamase FQV73_RS16890 ENOG41090UD (LipO)protein FQV73_RS16895 ENOG4108SUT Major Facilitator Superfamily FQV73_RS16900 ENOG4108TZY GntR Family Transcriptional Regulator FQV73_RS16905 ENOG4105JXH GntR family transcriptional regulator FQV73_RS16910 ENOG4105DJ2 Major Facilitator Superfamily FQV73_RS16930 ENOG4107QTZ amino acid FQV73_RS16950 ENOG4107QNK )-transporter FQV73_RS16990 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FQV73_RS16995 ENOG4105K8N protein family UPF0079, ATPase FQV73_RS17000 ENOG41072GX Peptidase M22 Glycoprotease FQV73_RS17005 ENOG410801F ribosomal-protein-alanine acetyltransferase FQV73_RS17010 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FQV73_RS17015 ENOG4105C5H ABC transporter FQV73_RS17020 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FQV73_RS17025 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) FQV73_RS17030 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FQV73_RS17035 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FQV73_RS17045 ENOG4108TYN CAAX amino terminal protease family protein FQV73_RS17055 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) FQV73_RS17060 ENOG4105ESF Peptidoglycan binding domain protein FQV73_RS17075 ENOG4105PGZ NB-ARC domain FQV73_RS17080 ENOG4105CPQ Dehydrogenase FQV73_RS17085 ENOG4105CT4 transporter FQV73_RS17100 ENOG41087YS Phage shock protein A FQV73_RS17105 ENOG4105DQX Zinc finger domain FQV73_RS17110 ENOG4108WV1 Pfam:DUF477 FQV73_RS17120 ENOG4105EXC Acyl-transferase FQV73_RS17125 ENOG4108P49 AntiSigma factor FQV73_RS17130 ENOG4105JVQ RNA Polymerase FQV73_RS17160 ENOG4107STQ Multicopper oxidase FQV73_RS17165 ENOG4105C85 amino acid FQV73_RS17170 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FQV73_RS17185 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FQV73_RS17200 ENOG4105C7N Xanthine uracil vitamin C permease FQV73_RS17225 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FQV73_RS17230 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FQV73_RS17235 ENOG4105C83 adenylosuccinate lyase FQV73_RS17240 ENOG4105C8V SAICAR synthetase FQV73_RS17245 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FQV73_RS17250 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I FQV73_RS17255 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii FQV73_RS17265 ENOG4105CXB phosphoribosylaminoimidazole synthetase FQV73_RS17270 ENOG4108V3E phosphoribosylglycinamide formyltransferase FQV73_RS17275 ENOG4105DC1 bifunctional purine biosynthesis protein purh FQV73_RS17280 ENOG4105C12 Phosphoribosylglycinamide synthetase FQV73_RS17295 ENOG4108R5T secreted protein FQV73_RS17300 ENOG4105KGF protein, YerC YecD FQV73_RS17305 ENOG4105CBC glutamate synthase FQV73_RS17315 ENOG4105C4R Atp-dependent dna helicase FQV73_RS17320 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FQV73_RS17330 ENOG4105CRN Aminoglycoside phosphotransferase FQV73_RS17335 ENOG4105KT7 mgtC SapB transporter FQV73_RS17340 ENOG4105CK7 Sodium proline symporter FQV73_RS17345 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FQV73_RS17350 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FQV73_RS17355 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FQV73_RS17360 ENOG4108IG5 Transcriptional regulator FQV73_RS17370 ENOG4105CBD Diacylglycerol kinase FQV73_RS17375 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FQV73_RS17385 ENOG4105CJ1 ABC, transporter FQV73_RS17420 ENOG4105CDY transcriptional regulatory protein FQV73_RS17430 ENOG41075D4 Aminoglycoside 6-adenylyltransferase FQV73_RS17445 ENOG4105WEF catalase FQV73_RS17450 ENOG4105M18 -acetyltransferase FQV73_RS17460 ENOG4105H67 Protein of unknown function (DUF421) FQV73_RS17465 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FQV73_RS17470 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FQV73_RS17490 ENOG4106I4J membrane FQV73_RS17500 ENOG4108R1P FQV73_RS17505 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FQV73_RS17510 ENOG4105E0M Sulfatase FQV73_RS17515 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase FQV73_RS17525 ENOG41090R9 glycosyltransferase FQV73_RS17530 ENOG4107R51 Glycosyl transferase, family 2 FQV73_RS17535 ENOG41090R9 glycosyltransferase FQV73_RS17540 ENOG4105EU0 Major facilitator Superfamily FQV73_RS17545 ENOG4105CUB amino acid FQV73_RS17550 ENOG4105C26 Dehydrogenase FQV73_RS17555 ENOG4105FKZ Methyl-accepting chemotaxis FQV73_RS17560 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FQV73_RS17565 ENOG4107TVC Glycosyl transferase, family 2 FQV73_RS17570 ENOG4105C5H ABC transporter FQV73_RS17575 ENOG4107SWG transcriptional regulator MERR family FQV73_RS17580 ENOG4105DXB Major Facilitator superfamily FQV73_RS17585 ENOG4105C5H ABC transporter FQV73_RS17590 ENOG4105FDU atp-dependent rna helicase FQV73_RS17600 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FQV73_RS17615 ENOG4108J20 pectate lyase FQV73_RS17620 ENOG4107QPK )-transporter FQV73_RS17645 ENOG4108VAC response regulator FQV73_RS17665 ENOG4108MRH transcriptional regulatory protein FQV73_RS17690 ENOG41084X4 Acylphosphatase (EC 3.6.1.7) FQV73_RS17695 ENOG4108RPX mosc domain containing protein FQV73_RS17715 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FQV73_RS17755 ENOG4105C5Y PTS System FQV73_RS17760 ENOG4105CG3 alpha amylase, catalytic region FQV73_RS17765 ENOG4107414 GntR family transcriptional regulator FQV73_RS17770 ENOG4108RCM Nitroreductase FQV73_RS17785 ENOG4105CGH 5'-nucleotidase FQV73_RS17790 ENOG4107RKG DJ-1/PfpI family FQV73_RS17795 ENOG4105ETE Transcriptional regulator (LacI family FQV73_RS17805 ENOG4105FF2 Type I DHQase FQV73_RS17820 ENOG4105KJF protein tyrosine phosphatase FQV73_RS17830 ENOG4107U9T Pfam:Ribonuclease_BN FQV73_RS17835 ENOG4108ISG Major Facilitator FQV73_RS17840 ENOG4105UPD Calcium Proton FQV73_RS17850 ENOG4105D8X mechanosensitive ion channel FQV73_RS17870 ENOG4106KE4 Dehydrogenase FQV73_RS17880 ENOG4105D7N magnesium and cobalt transport protein CorA FQV73_RS17890 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FQV73_RS17910 ENOG4107RUY (E1 component), alpha subunit FQV73_RS17920 ENOG4107QKR Dehydrogenase FQV73_RS17930 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FQV73_RS17940 ENOG4105F8D glycoside hydrolase family 4 FQV73_RS17945 ENOG4108Q3X Transcriptional regulator FQV73_RS17950 ENOG4105CI1 PTS System FQV73_RS17955 ENOG4105BZ1 (ABC) transporter FQV73_RS17960 ENOG4105BZ1 (ABC) transporter FQV73_RS17970 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FQV73_RS17975 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) FQV73_RS17980 ENOG4105U3E Transcriptional regulator FQV73_RS17985 ENOG4105DYS nad(p)h dehydrogenase (quinone) FQV73_RS17990 ENOG4105H93 Acyltransferase family FQV73_RS18005 ENOG4108YYS metal-dependent hydrolase (By similarity) FQV73_RS18010 ENOG4105C0R drug resistance transporter emrb qaca subfamily FQV73_RS18015 ENOG410834F Transcriptional regulator FQV73_RS18025 ENOG4105JAB phenazine biosynthesis protein, phzf family FQV73_RS18030 ENOG4107Y03 Nitroreductase FQV73_RS18045 ENOG4105ECP epimerase FQV73_RS18050 ENOG410902V Modulates RecA activity (By similarity) FQV73_RS18060 ENOG4105F27 Major Facilitator FQV73_RS18070 ENOG4108TCS Glutamyl endopeptidase FQV73_RS18090 ENOG4106AKJ FQV73_RS18095 ENOG4105D74 hydrolase FQV73_RS18100 ENOG4105CKK Glycosyl transferase, family 2 FQV73_RS18105 ENOG4105EJV Membrane FQV73_RS18110 ENOG41067AE Membrane-bound metal-dependent hydrolase FQV73_RS18115 ENOG4105CEN a g-specific adenine glycosylase FQV73_RS18120 ENOG4106BXE FQV73_RS18125 ENOG4105CAN Short-chain dehydrogenase reductase Sdr FQV73_RS18145 ENOG4105BZ1 (ABC) transporter FQV73_RS18150 ENOG4107NBY Membrane FQV73_RS18155 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase FQV73_RS18160 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FQV73_RS18165 ENOG4105G5W regulator Fur family FQV73_RS18170 ENOG4105TUA UPF0295 protein FQV73_RS18285 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) FQV73_RS18290 ENOG4105DNP FAD linked oxidase domain protein FQV73_RS18300 ENOG4105DEF Extracellular solute-binding protein, family 5 FQV73_RS18310 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FQV73_RS18315 ENOG4105C3U ABC transporter FQV73_RS18320 ENOG4108JQ7 (ABC) transporter FQV73_RS18335 ENOG4105E2Y ABC, transporter FQV73_RS18340 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FQV73_RS18345 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FQV73_RS18355 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) FQV73_RS18360 ENOG4107D63 FQV73_RS18365 ENOG4105VZ8 Transcriptional regulator FQV73_RS18380 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FQV73_RS18390 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FQV73_RS18410 ENOG4105CYN Serine protein kinase FQV73_RS18420 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FQV73_RS18425 ENOG4105CW7 secretion protein, HlyD family FQV73_RS18430 ENOG4105C0R drug resistance transporter emrb qaca subfamily FQV73_RS18435 ENOG4105CS1 NAD(P)H quinone oxidoreductase FQV73_RS18450 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FQV73_RS18455 ENOG4105CZV ABC transporter FQV73_RS18460 ENOG4105CJ1 ABC, transporter FQV73_RS18465 ENOG4108TU7 Inherit from COG: (ABC) transporter FQV73_RS18470 ENOG4105VEQ Cold shock protein FQV73_RS18480 ENOG4105BZU Histidine kinase FQV73_RS18520 ENOG4108YBP pseudouridine synthase FQV73_RS18530 ENOG41080XP Cbs domain FQV73_RS18535 ENOG4107YBY Hydrolase FQV73_RS18540 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FQV73_RS18545 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FQV73_RS18550 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FQV73_RS18560 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FQV73_RS18565 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FQV73_RS18615 ENOG4105ED1 spovr family FQV73_RS18620 ENOG4105G6Z alkaline phosphatase FQV73_RS18635 ENOG4105BZN citrate synthase FQV73_RS18640 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FQV73_RS18645 ENOG4105CUB amino acid FQV73_RS18650 ENOG4105C8J )-transporter FQV73_RS18660 ENOG4105J37 FQV73_RS18665 ENOG4108AEY RNA polymerase sigma factor FQV73_RS18670 ENOG4105F6E Acyl-transferase FQV73_RS18675 ENOG4105C37 (CBS) domain FQV73_RS18685 ENOG4105CHM Aminotransferase FQV73_RS18690 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase FQV73_RS18695 ENOG4105C37 (CBS) domain FQV73_RS18705 ENOG4105WMR Protein CrcB homolog FQV73_RS18710 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FQV73_RS18720 ENOG4105D64 Mechanosensitive ion channel FQV73_RS18725 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FQV73_RS18730 ENOG4107VMI polysaccharide deacetylase FQV73_RS18735 ENOG4105F0I Aminotransferase FQV73_RS18740 ENOG4105W1N transcriptional regulator FQV73_RS18745 ENOG4105IIP Membrane FQV73_RS18755 ENOG4105BZ1 (ABC) transporter FQV73_RS18760 ENOG4105BZ1 (ABC) transporter FQV73_RS18780 ENOG410839P FQV73_RS18790 ENOG4106MP8 UPF0754 membrane protein FQV73_RS18795 ENOG4105WZB UPF0342 protein FQV73_RS18800 ENOG4105F1N DNA alkylation repair FQV73_RS18810 ENOG4105D4P Coproporphyrinogen iii oxidase FQV73_RS18820 ENOG4107S91 Sodium hydrogen exchanger FQV73_RS18825 ENOG4105NCW Trka-c domain protein FQV73_RS18835 ENOG4105CGU Enoyl-CoA hydratase FQV73_RS18845 ENOG4108IUX (ABC) transporter FQV73_RS18850 ENOG4105RHA ABC transporter, permease FQV73_RS18855 ENOG4107VRP DNA repair exonuclease FQV73_RS18860 ENOG4106D4I domain protein FQV73_RS18865 ENOG4105EQI Metal Dependent Phosphohydrolase FQV73_RS18875 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FQV73_RS18920 ENOG4105NBU tryptophan transport protein FQV73_RS18925 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) FQV73_RS18930 ENOG4105K59 histidine triad (HIT) protein FQV73_RS18960 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FQV73_RS18965 ENOG4105BZ4 penicillin-binding protein FQV73_RS18970 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) FQV73_RS18975 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FQV73_RS18980 ENOG4105C1Q protoporphyrinogen oxidase FQV73_RS18990 ENOG4105ECB domain protein FQV73_RS19005 ENOG4105DER m42 family FQV73_RS19015 ENOG4106AXD FQV73_RS19020 ENOG4108RQ5 Beta-lactamase domain-containing protein FQV73_RS19025 ENOG4105DF9 Lipoate-protein, ligase FQV73_RS19035 ENOG4105CEY Amp-dependent synthetase and ligase FQV73_RS19045 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FQV73_RS19065 ENOG4107TB6 phosphoglycerate mutase FQV73_RS19075 ENOG4107F3J Amp-dependent synthetase and ligase FQV73_RS19080 ENOG4107ZYJ bioY protein FQV73_RS19085 ENOG4106YBV Methyl-accepting chemotaxis FQV73_RS19105 ENOG4105XVF Competence transcription factor FQV73_RS19115 ENOG4108ZMX Domain of unknown function (DU1801) FQV73_RS19125 ENOG4105X3H Excalibur domain protein FQV73_RS19130 ENOG4105K8R UPF0145 protein FQV73_RS19135 ENOG4105E1V na solute symporter FQV73_RS19140 ENOG4106CAD Protein of unknown function (DUF3311) FQV73_RS19145 ENOG41060YP FQV73_RS19160 ENOG4107SCK Monooxygenase FQV73_RS19165 ENOG4108INS Transcriptional regulator FQV73_RS19170 ENOG4108KK1 membrane protein AbrB duplication FQV73_RS19180 ENOG4108IG5 Transcriptional regulator FQV73_RS19190 ENOG4108QY0 Membrane FQV73_RS19195 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination FQV73_RS19200 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FQV73_RS19210 ENOG4105EYH Exonuclease FQV73_RS19255 ENOG4105ERH Fumarylacetoacetate hydrolase FQV73_RS19275 ENOG4105CAQ asparagine synthetase FQV73_RS19285 ENOG4105UQX Mate efflux family protein FQV73_RS19290 ENOG4106HBX Transcriptional Regulator AraC Family FQV73_RS19295 ENOG4105ETE Transcriptional regulator (LacI family FQV73_RS19300 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FQV73_RS19305 ENOG4105SF0 DinB family