locus-tag	class	description
CXP43_RS00010	COG0592	DNA-directed DNA polymerase activity
CXP43_RS00015	COG2501	S4 domain
CXP43_RS00030	COG0187	DNA topoisomerase II activity
CXP43_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXP43_RS00070	COG0516	GMP reductase activity
CXP43_RS00070	COG0517	IMP dehydrogenase activity
CXP43_RS00075	COG1686	Belongs to the peptidase S11 family
CXP43_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
CXP43_RS00105	COG1428	Deoxynucleoside kinase
CXP43_RS00110	COG1428	Deoxynucleoside kinase
CXP43_RS00115	COG1388	LysM domain
CXP43_RS00115	COG3858	chitin binding
CXP43_RS00120	COG1335	isochorismatase
CXP43_RS00125	COG0590	tRNA wobble adenosine to inosine editing
CXP43_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CXP43_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CXP43_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CXP43_RS00195	COG3853	Toxic anion resistance protein (TelA)
CXP43_RS00200	COG1982	Orn Lys Arg decarboxylase major
CXP43_RS00210	COG3870	Protein conserved in bacteria
CXP43_RS00215	COG1728	Protein conserved in bacteria
CXP43_RS00220	COG0470	DNA polymerase III
CXP43_RS00225	COG1774	PSP1 C-terminal conserved region
CXP43_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CXP43_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CXP43_RS00250	COG2002	toxin-antitoxin pair type II binding
CXP43_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXP43_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXP43_RS00260	COG0084	hydrolase, TatD family'
CXP43_RS00265	COG3584	3D domain protein
CXP43_RS00265	COG3583	domain protein
CXP43_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CXP43_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CXP43_RS00285	COG4466	Protein conserved in bacteria
CXP43_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CXP43_RS00305	COG0251	oxidation-reduction process
CXP43_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXP43_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CXP43_RS00350	COG2002	toxin-antitoxin pair type II binding
CXP43_RS00355	COG2244	polysaccharide biosynthetic process
CXP43_RS00360	COG3956	TIGRFAM MazG family protein
CXP43_RS00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CXP43_RS00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CXP43_RS00385	COG1098	S1 RNA binding domain
CXP43_RS00400	COG2208	phosphoserine phosphatase activity
CXP43_RS00405	COG2304	oxidoreductase activity
CXP43_RS00410	COG0515	serine threonine protein kinase
CXP43_RS00415	COG0037	tRNA processing
CXP43_RS00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CXP43_RS00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXP43_RS00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXP43_RS00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXP43_RS00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXP43_RS00455	COG0512	Glutamine amidotransferase of anthranilate synthase
CXP43_RS00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXP43_RS00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CXP43_RS00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXP43_RS00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CXP43_RS00480	COG1396	sequence-specific DNA binding
CXP43_RS00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXP43_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CXP43_RS00575	COG4463	regulation of RNA biosynthetic process
CXP43_RS00580	COG3880	PFAM UvrB UvrC protein
CXP43_RS00590	COG0542	response to heat
CXP43_RS00595	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CXP43_RS00600	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CXP43_RS00605	COG4956	integral membrane protein (PIN domain superfamily)
CXP43_RS00625	COG1045	serine acetyltransferase
CXP43_RS00635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CXP43_RS00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXP43_RS00645	COG3688	RNA-binding protein containing a PIN domain
CXP43_RS00650	COG1595	DNA-templated transcription, initiation
CXP43_RS00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXP43_RS00665	COG0250	Participates in transcription elongation, termination and antitermination
CXP43_RS00690	COG2813	Specifically methylates the guanine in position
CXP43_RS00705	COG1358	cellular component organization or biogenesis
CXP43_RS00730	COG0596	Alpha beta hydrolase
CXP43_RS00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CXP43_RS00840	COG0201	protein transport
CXP43_RS00850	COG0024	Methionine aminopeptidase
CXP43_RS00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CXP43_RS00890	COG1122	ATPase activity
CXP43_RS00895	COG1122	ATPase activity
CXP43_RS00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CXP43_RS00920	COG2226	methyltransferase
CXP43_RS00925	COG2318	DinB family
CXP43_RS00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS00940	COG0489	protein tyrosine kinase activity
CXP43_RS00950	COG2194	sulfuric ester hydrolase activity
CXP43_RS00955	COG0726	polysaccharide deacetylase
CXP43_RS01015	COG0738	Major facilitator superfamily
CXP43_RS01020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXP43_RS01035	COG0659	secondary active sulfate transmembrane transporter activity
CXP43_RS01040	COG0385	Bile acid
CXP43_RS01045	COG2819	hydrolase of the alpha beta superfamily
CXP43_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXP43_RS01055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXP43_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXP43_RS01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXP43_RS01065	COG2207	Transcriptional regulator
CXP43_RS01070	COG3876	Protein conserved in bacteria
CXP43_RS01075	COG1472	Belongs to the glycosyl hydrolase 3 family
CXP43_RS01080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXP43_RS01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXP43_RS01085	COG1263	PTS System
CXP43_RS01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXP43_RS01100	COG1683	Conserved Protein
CXP43_RS01130	COG1595	DNA-templated transcription, initiation
CXP43_RS01135	COG5662	AntiSigma factor
CXP43_RS01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CXP43_RS01145	COG4856	YbbR-like protein
CXP43_RS01190	COG1346	cytolysis
CXP43_RS01195	COG1380	Effector of murein hydrolase LrgA
CXP43_RS01200	COG1846	Transcriptional regulator
CXP43_RS01205	COG1113	amino acid transport
CXP43_RS01210	COG1011	Hydrolase
CXP43_RS01215	COG4585	Histidine kinase
CXP43_RS01220	COG2197	response regulator
CXP43_RS01225	COG1131	(ABC) transporter
CXP43_RS01265	COG0531	amino acid
CXP43_RS01270	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CXP43_RS01285	COG0584	glycerophosphoryl diester phosphodiesterase
CXP43_RS01290	COG2271	Major facilitator Superfamily
CXP43_RS01305	COG2368	4-hydroxyphenylacetate
CXP43_RS01315	COG3409	Peptidoglycan-binding domain 1 protein
CXP43_RS01330	COG0371	Dehydrogenase
CXP43_RS01340	COG1183	phosphatidylcholine synthase activity
CXP43_RS01345	COG0586	Pfam SNARE associated Golgi protein
CXP43_RS01350	COG0688	phosphatidylethanolamine metabolic process
CXP43_RS01365	COG1301	dicarboxylic acid transport
CXP43_RS01370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXP43_RS01375	COG0833	amino acid
CXP43_RS01380	COG2040	homocysteine
CXP43_RS01385	COG1115	amino acid carrier protein
CXP43_RS01390	COG2066	Belongs to the glutaminase family
CXP43_RS01395	COG4191	Histidine kinase
CXP43_RS01400	COG0784	Response regulator, receiver
CXP43_RS01405	COG3173	Aminoglycoside phosphotransferase
CXP43_RS01425	COG3773	Cell wall hydrolase
CXP43_RS01435	COG3540	Alkaline phosphatase
CXP43_RS01440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXP43_RS01445	COG0805	protein transport
CXP43_RS01455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXP43_RS01460	COG0477	Major facilitator Superfamily
CXP43_RS01465	COG1309	transcriptional regulator
CXP43_RS01470	COG0252	asparaginase activity
CXP43_RS01475	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CXP43_RS01480	COG3012	SEC-C Motif Domain Protein
CXP43_RS01480	COG1405	negative regulation of cell septum assembly
CXP43_RS01485	COG0667	Aldo Keto reductase
CXP43_RS01495	COG1595	DNA-templated transcription, initiation
CXP43_RS01500	COG1595	DNA-templated transcription, initiation
CXP43_RS01505	COG1876	peptidase activity
CXP43_RS01510	COG0457	Tetratricopeptide repeat
CXP43_RS01515	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS01520	COG0366	Alpha amylase catalytic
CXP43_RS01525	COG0803	Belongs to the bacterial solute-binding protein 9 family
CXP43_RS01530	COG1121	(ABC) transporter
CXP43_RS01535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXP43_RS01540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXP43_RS01545	COG2310	stress, protein
CXP43_RS01550	COG2310	stress, protein
CXP43_RS01555	COG2310	stress, protein
CXP43_RS01560	COG0861	Integral membrane protein TerC family
CXP43_RS01570	COG3853	Toxic anion resistance protein (TelA)
CXP43_RS01575	COG0477	Major facilitator Superfamily
CXP43_RS01580	COG0517	IMP dehydrogenase activity
CXP43_RS01580	COG4175	Glycine betaine
CXP43_RS01585	COG4176	ABC-type proline glycine betaine transport system permease component
CXP43_RS01590	COG2113	Glycine betaine
CXP43_RS01595	COG1473	amidohydrolase
CXP43_RS01600	COG1288	antiporter activity
CXP43_RS01610	COG0366	Alpha amylase catalytic
CXP43_RS01620	COG2814	Major facilitator Superfamily
CXP43_RS01625	COG1846	Transcriptional regulator
CXP43_RS01630	COG1280	lysine exporter protein (LysE YggA)
CXP43_RS01635	COG3403	YqcI/YcgG family
CXP43_RS01640	COG1113	amino acid transport
CXP43_RS01645	COG3665	Urea carboxylase-associated protein
CXP43_RS01660	COG1660	Displays ATPase and GTPase activities
CXP43_RS01670	COG2271	Major facilitator Superfamily
CXP43_RS01675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CXP43_RS01680	COG3458	cephalosporin-C deacetylase activity
CXP43_RS01685	COG3541	Predicted nucleotidyltransferase
CXP43_RS01690	COG0506	proline dehydrogenase activity
CXP43_RS01695	COG1012	belongs to the aldehyde dehydrogenase family
CXP43_RS01700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXP43_RS01705	COG2508	Transcriptional regulator
CXP43_RS01715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CXP43_RS01715	COG1587	Uroporphyrinogen-III synthase
CXP43_RS01720	COG2146	nitrite reductase [NAD(P)H] activity
CXP43_RS01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CXP43_RS01730	COG0243	molybdopterin cofactor binding
CXP43_RS01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CXP43_RS01740	COG2223	nitrite transmembrane transporter activity
CXP43_RS01745	COG0523	cobalamin synthesis protein
CXP43_RS01750	COG1063	alcohol dehydrogenase
CXP43_RS01755	COG1714	RDD family
CXP43_RS01765	COG2723	6-phospho-beta-galactosidase activity
CXP43_RS01775	COG3209	COG3209 Rhs family protein
CXP43_RS01780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CXP43_RS01785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CXP43_RS01790	COG1733	regulation of RNA biosynthetic process
CXP43_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS01815	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CXP43_RS01830	COG2364	Membrane
CXP43_RS01835	COG1126	abc transporter atp-binding protein
CXP43_RS01840	COG0765	amino acid transport
CXP43_RS01845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXP43_RS01850	COG0583	DNA-binding transcription factor activity
CXP43_RS01855	COG0163	prenyltransferase activity
CXP43_RS01860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CXP43_RS01875	COG3104	oligopeptide transport
CXP43_RS01880	COG5434	Belongs to the glycosyl hydrolase 28 family
CXP43_RS01890	COG0697	spore germination
CXP43_RS01900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CXP43_RS01905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXP43_RS01910	COG0456	acetyltransferase
CXP43_RS01915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXP43_RS01920	COG0765	amino acid transport
CXP43_RS01925	COG1126	abc transporter atp-binding protein
CXP43_RS01930	COG1473	amidohydrolase
CXP43_RS01935	COG2079	MmgE PrpD family protein
CXP43_RS01940	COG1136	(ABC) transporter
CXP43_RS01945	COG0577	efflux transmembrane transporter activity
CXP43_RS01950	COG0745	RESPONSE REGULATOR receiver
CXP43_RS01955	COG5002	protein histidine kinase activity
CXP43_RS01955	COG3850	Histidine kinase
CXP43_RS01960	COG0457	Tetratricopeptide repeat
CXP43_RS01975	COG0527	aspartate kinase activity
CXP43_RS01980	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXP43_RS01985	COG4605	iron ion homeostasis
CXP43_RS01990	COG4604	ABC transporter, ATP-binding protein
CXP43_RS01995	COG4607	ABC-type enterochelin transport system periplasmic component
CXP43_RS02000	COG2814	Major facilitator Superfamily
CXP43_RS02005	COG1309	transcriptional regulator
CXP43_RS02010	COG0778	Nitroreductase
CXP43_RS02015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXP43_RS02020	COG0640	Transcriptional regulator
CXP43_RS02025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXP43_RS02030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXP43_RS02035	COG1012	belongs to the aldehyde dehydrogenase family
CXP43_RS02040	COG4975	Glucose uptake
CXP43_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS02050	COG4549	nuclear export factor GLE1
CXP43_RS02055	COG2372	response to copper ion
CXP43_RS02055	COG1276	copper resistance
CXP43_RS02060	COG1349	DNA-binding transcription factor activity
CXP43_RS02070	COG2213	PTS system mannitol-specific
CXP43_RS02075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXP43_RS02085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CXP43_RS02095	COG0561	phosphatase activity
CXP43_RS02105	COG1914	H( )-stimulated, divalent metal cation uptake system
CXP43_RS02115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CXP43_RS02120	COG1984	allophanate hydrolase subunit 2
CXP43_RS02125	COG1414	Transcriptional regulator
CXP43_RS02130	COG2755	lipolytic protein G-D-S-L family
CXP43_RS02140	COG2329	Antibiotic biosynthesis monooxygenase
CXP43_RS02145	COG0768	penicillin binding
CXP43_RS02150	COG4989	oxidoreductase activity
CXP43_RS02155	COG3711	transcriptional antiterminator
CXP43_RS02160	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS02165	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS02170	COG1917	Cupin 2, conserved barrel domain protein
CXP43_RS02175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXP43_RS02180	COG3871	stress protein (general stress protein 26)
CXP43_RS02190	COG2814	Major facilitator Superfamily
CXP43_RS02195	COG1522	sequence-specific DNA binding
CXP43_RS02200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXP43_RS02200	COG0551	DNA topoisomerase type I activity
CXP43_RS02205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CXP43_RS02210	COG3706	GGDEF domain
CXP43_RS02215	COG5298	Protein conserved in bacteria
CXP43_RS02220	COG1215	transferase activity, transferring glycosyl groups
CXP43_RS02230	COG0531	amino acid
CXP43_RS02235	COG0494	nUDIX hydrolase
CXP43_RS02240	COG0028	Belongs to the TPP enzyme family
CXP43_RS02275	COG1914	H( )-stimulated, divalent metal cation uptake system
CXP43_RS02290	COG4876	unkown
CXP43_RS02300	COG2076	Multidrug Resistance protein
CXP43_RS02305	COG2217	Heavy metal translocating P-type atpase
CXP43_RS02310	COG3729	General stress protein
CXP43_RS02315	COG0662	Cupin 2, conserved barrel domain protein
CXP43_RS02320	COG2329	Antibiotic biosynthesis monooxygenase
CXP43_RS02325	COG3546	catalase activity
CXP43_RS02330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXP43_RS02335	COG3290	protein histidine kinase activity
CXP43_RS02340	COG4565	transcriptional regulatory protein
CXP43_RS02345	COG1301	dicarboxylic acid transport
CXP43_RS02350	COG0628	permease
CXP43_RS02355	COG1131	(ABC) transporter
CXP43_RS02360	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CXP43_RS02370	COG1960	acyl-CoA dehydrogenase activity
CXP43_RS02385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXP43_RS02390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXP43_RS02400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CXP43_RS02405	COG0513	Belongs to the DEAD box helicase family
CXP43_RS02410	COG3402	PFAM membrane-flanked domain
CXP43_RS02415	COG3428	Bacterial PH domain
CXP43_RS02420	COG0705	Rhomboid family
CXP43_RS02430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CXP43_RS02435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXP43_RS02440	COG0864	Transcriptional regulator
CXP43_RS02445	COG2337	Toxic component of a toxin-antitoxin (TA) module
CXP43_RS02450	COG1366	Belongs to the anti-sigma-factor antagonist family
CXP43_RS02455	COG1366	Belongs to the anti-sigma-factor antagonist family
CXP43_RS02460	COG2172	sigma factor antagonist activity
CXP43_RS02465	COG2208	phosphoserine phosphatase activity
CXP43_RS02470	COG1366	Belongs to the anti-sigma-factor antagonist family
CXP43_RS02480	COG1191	sigma factor activity
CXP43_RS02485	COG2208	phosphoserine phosphatase activity
CXP43_RS02490	COG2183	response to ionizing radiation
CXP43_RS02565	COG0457	Tetratricopeptide repeat
CXP43_RS02575	COG0477	Major facilitator Superfamily
CXP43_RS02595	COG2030	dehydratase
CXP43_RS02610	COG1959	2 iron, 2 sulfur cluster binding
CXP43_RS02615	COG2910	NAD(P)H-binding
CXP43_RS02625	COG1309	transcriptional regulator
CXP43_RS02630	COG3239	Fatty acid desaturase
CXP43_RS02640	COG1278	Cold shock
CXP43_RS02645	COG1329	Transcriptional regulator
CXP43_RS02650	COG1937	Protein conserved in bacteria
CXP43_RS02655	COG2210	Belongs to the sulfur carrier protein TusA family
CXP43_RS02660	COG1054	Belongs to the UPF0176 family
CXP43_RS02665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXP43_RS02665	COG0425	Belongs to the sulfur carrier protein TusA family
CXP43_RS02670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXP43_RS02670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXP43_RS02675	COG0425	Belongs to the sulfur carrier protein TusA family
CXP43_RS02680	COG0730	response to heat
CXP43_RS02685	COG1794	racemase activity, acting on amino acids and derivatives
CXP43_RS02700	COG3621	Patatin-like phospholipase
CXP43_RS02710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXP43_RS02715	COG1802	Transcriptional regulator
CXP43_RS02720	COG0251	oxidation-reduction process
CXP43_RS02725	COG0814	amino acid
CXP43_RS02730	COG1473	amidohydrolase
CXP43_RS02735	COG2207	Transcriptional regulator
CXP43_RS02735	COG1917	Cupin 2, conserved barrel domain protein
CXP43_RS02745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXP43_RS02750	COG0477	Major facilitator Superfamily
CXP43_RS02770	COG0277	FAD linked oxidase domain protein
CXP43_RS02800	COG2318	DinB family
CXP43_RS02830	COG0351	phosphomethylpyrimidine kinase
CXP43_RS02845	COG1064	alcohol dehydrogenase
CXP43_RS02850	COG0789	Transcriptional regulator
CXP43_RS02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXP43_RS02875	COG2814	Major facilitator Superfamily
CXP43_RS02880	COG1309	transcriptional regulator
CXP43_RS02885	COG0697	spore germination
CXP43_RS02890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXP43_RS02895	COG5577	PFAM Coat F domain
CXP43_RS02905	COG1063	alcohol dehydrogenase
CXP43_RS02910	COG5577	PFAM Coat F domain
CXP43_RS02920	COG0738	Major facilitator superfamily
CXP43_RS02935	COG4585	Histidine kinase
CXP43_RS02940	COG2197	response regulator
CXP43_RS02945	COG2409	Drug exporters of the RND superfamily
CXP43_RS02950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CXP43_RS02955	COG0488	(ABC) transporter
CXP43_RS02960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXP43_RS02965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXP43_RS02975	COG2814	Major facilitator Superfamily
CXP43_RS02980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXP43_RS02990	COG0730	response to heat
CXP43_RS02995	COG0456	acetyltransferase
CXP43_RS03000	COG0789	Transcriptional regulator
CXP43_RS03000	COG4978	Transcriptional regulator
CXP43_RS03005	COG0697	spore germination
CXP43_RS03010	COG1051	belongs to the nudix hydrolase family
CXP43_RS03015	COG2226	methyltransferase
CXP43_RS03020	COG0473	3-isopropylmalate dehydrogenase activity
CXP43_RS03025	COG1802	Transcriptional regulator
CXP43_RS03030	COG1819	glycosyl
CXP43_RS03045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXP43_RS03050	COG1388	LysM domain
CXP43_RS03055	COG2814	Major facilitator Superfamily
CXP43_RS03060	COG2188	Transcriptional regulator
CXP43_RS03065	COG2186	Transcriptional regulator
CXP43_RS03070	COG2807	transmembrane transport
CXP43_RS03075	COG2076	Multidrug Resistance protein
CXP43_RS03080	COG2076	Multidrug Resistance protein
CXP43_RS03085	COG1309	transcriptional regulator
CXP43_RS03090	COG0531	amino acid
CXP43_RS03100	COG3832	glyoxalase III activity
CXP43_RS03105	COG0604	alcohol dehydrogenase
CXP43_RS03110	COG2814	Major facilitator Superfamily
CXP43_RS03150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CXP43_RS03155	COG0802	atpase or kinase
CXP43_RS03160	COG1214	PFAM Peptidase M22, glycoprotease
CXP43_RS03165	COG0456	acetyltransferase
CXP43_RS03170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CXP43_RS03175	COG0488	(ABC) transporter
CXP43_RS03190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXP43_RS03195	COG0805	protein transport
CXP43_RS03205	COG1266	CAAX protease self-immunity
CXP43_RS03230	COG0457	Tetratricopeptide repeat
CXP43_RS03235	COG1063	alcohol dehydrogenase
CXP43_RS03240	COG2211	Major facilitator Superfamily
CXP43_RS03245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXP43_RS03255	COG1842	Phage shock protein A
CXP43_RS03260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXP43_RS03265	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXP43_RS03270	COG4260	virion core protein, lumpy skin disease virus
CXP43_RS03275	COG2755	lipolytic protein G-D-S-L family
CXP43_RS03275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CXP43_RS03285	COG1595	DNA-templated transcription, initiation
CXP43_RS03290	COG1063	alcohol dehydrogenase
CXP43_RS03295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXP43_RS03300	COG0823	Involved in the tonB-independent uptake of proteins
CXP43_RS03310	COG2132	Multicopper oxidase
CXP43_RS03315	COG1113	amino acid transport
CXP43_RS03320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXP43_RS03325	COG0714	Associated with various cellular activities
CXP43_RS03330	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CXP43_RS03335	COG1305	Transglutaminase-like
CXP43_RS03345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXP43_RS03365	COG2211	Major facilitator Superfamily
CXP43_RS03380	COG2252	PERMEase
CXP43_RS03385	COG3064	Membrane
CXP43_RS03405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXP43_RS03410	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CXP43_RS03415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXP43_RS03420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CXP43_RS03425	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CXP43_RS03440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CXP43_RS03450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXP43_RS03455	COG0138	bifunctional purine biosynthesis protein purh
CXP43_RS03460	COG0151	Belongs to the GarS family
CXP43_RS03470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CXP43_RS03475	COG1470	cell adhesion involved in biofilm formation
CXP43_RS03480	COG4496	protein, YerC YecD
CXP43_RS03485	COG0069	glutamate synthase activity
CXP43_RS03500	COG0210	DNA helicase
CXP43_RS03510	COG4851	CamS sex pheromone cAM373 precursor
CXP43_RS03515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXP43_RS03520	COG1285	pathogenesis
CXP43_RS03525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXP43_RS03545	COG1309	transcriptional regulator
CXP43_RS03550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXP43_RS03555	COG1597	lipid kinase activity
CXP43_RS03560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXP43_RS03565	COG1136	(ABC) transporter
CXP43_RS03575	COG1131	(ABC) transporter
CXP43_RS03650	COG3546	catalase activity
CXP43_RS03655	COG0454	-acetyltransferase
CXP43_RS03665	COG2323	membrane
CXP43_RS03670	COG2329	Antibiotic biosynthesis monooxygenase
CXP43_RS03680	COG1366	Belongs to the anti-sigma-factor antagonist family
CXP43_RS03685	COG5583	Uncharacterized small protein (DUF2292)
CXP43_RS03690	COG0196	riboflavin kinase activity
CXP43_RS03695	COG0670	Belongs to the BI1 family
CXP43_RS03700	COG1846	Transcriptional regulator
CXP43_RS03705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXP43_RS03715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CXP43_RS03715	COG2124	cytochrome p450
CXP43_RS03730	COG1131	(ABC) transporter
CXP43_RS03745	COG1368	sulfuric ester hydrolase activity
CXP43_RS03750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CXP43_RS03755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXP43_RS03760	COG1442	glycosyl transferase family 8
CXP43_RS03765	COG1216	Glycosyl transferase, family 2
CXP43_RS03770	COG1442	glycosyl transferase family 8
CXP43_RS03775	COG2223	nitrite transmembrane transporter activity
CXP43_RS03780	COG0531	amino acid
CXP43_RS03785	COG1012	belongs to the aldehyde dehydrogenase family
CXP43_RS03790	COG0840	transmembrane signaling receptor activity
CXP43_RS03795	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS03800	COG0463	Glycosyl transferase, family 2
CXP43_RS03800	COG0457	Tetratricopeptide repeat
CXP43_RS03805	COG0488	(ABC) transporter
CXP43_RS03810	COG0789	Transcriptional regulator
CXP43_RS03815	COG2814	Major facilitator Superfamily
CXP43_RS03820	COG0488	(ABC) transporter
CXP43_RS03825	COG0513	Belongs to the DEAD box helicase family
CXP43_RS03835	COG2130	NADP-dependent
CXP43_RS03850	COG3866	Pectate lyase
CXP43_RS03855	COG0471	metal ion transport
CXP43_RS03870	COG0745	RESPONSE REGULATOR receiver
CXP43_RS03870	COG2972	Histidine kinase
CXP43_RS03875	COG3279	Response regulator of the LytR AlgR family
CXP43_RS03885	COG3764	Sortase (surface protein transpeptidase)
CXP43_RS03890	COG3290	protein histidine kinase activity
CXP43_RS03895	COG4565	transcriptional regulatory protein
CXP43_RS03900	COG3181	Tripartite tricarboxylate transporter family receptor
CXP43_RS03905	COG2851	Citrate transporter
CXP43_RS03910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXP43_RS03915	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CXP43_RS03925	COG2258	MOSC domain
CXP43_RS03945	COG0024	Methionine aminopeptidase
CXP43_RS03950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXP43_RS03950	COG1263	PTS System
CXP43_RS03960	COG1368	sulfuric ester hydrolase activity
CXP43_RS03970	COG0071	Belongs to the small heat shock protein (HSP20) family
CXP43_RS03985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXP43_RS03985	COG1263	PTS System
CXP43_RS03990	COG0366	Alpha amylase catalytic
CXP43_RS03995	COG2188	Transcriptional regulator
CXP43_RS04000	COG0778	Nitroreductase
CXP43_RS04015	COG0737	Belongs to the 5'-nucleotidase family
CXP43_RS04020	COG0693	protein deglycase activity
CXP43_RS04025	COG1609	Transcriptional regulator
CXP43_RS04040	COG2814	Major facilitator Superfamily
CXP43_RS04050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXP43_RS04055	COG4980	gas vesicle protein
CXP43_RS04060	COG1295	ribonuclease BN
CXP43_RS04065	COG0477	Major facilitator Superfamily
CXP43_RS04070	COG0387	Pfam Sodium calcium exchanger
CXP43_RS04080	COG0668	transmembrane transport
CXP43_RS04085	COG0535	radical SAM domain protein
CXP43_RS04095	COG0726	polysaccharide deacetylase
CXP43_RS04115	COG0745	RESPONSE REGULATOR receiver
CXP43_RS04120	COG2205	protein histidine kinase activity
CXP43_RS04125	COG2084	Dehydrogenase
CXP43_RS04135	COG0598	Magnesium transport protein CorA
CXP43_RS04140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CXP43_RS04145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXP43_RS04160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXP43_RS04165	COG4637	Psort location Cytoplasmic, score
CXP43_RS04170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CXP43_RS04175	COG0022	dehydrogenase e1 component
CXP43_RS04180	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXP43_RS04185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXP43_RS04190	COG3284	Transcriptional regulator
CXP43_RS04200	COG1486	melibiose metabolic process
CXP43_RS04205	COG1737	Transcriptional regulator
CXP43_RS04210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXP43_RS04210	COG1263	PTS System
CXP43_RS04215	COG1132	(ABC) transporter
CXP43_RS04220	COG1132	(ABC) transporter
CXP43_RS04225	COG2259	Doxx family
CXP43_RS04230	COG2514	catechol 2,3-dioxygenase activity
CXP43_RS04245	COG1695	Transcriptional regulator
CXP43_RS04250	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXP43_RS04255	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CXP43_RS04265	COG0574	Belongs to the PEP-utilizing enzyme family
CXP43_RS04265	COG3848	Pyruvate phosphate dikinase
CXP43_RS04270	COG2732	(Barnase) inhibitor
CXP43_RS04275	COG2318	DinB family
CXP43_RS04280	COG2814	Major facilitator Superfamily
CXP43_RS04285	COG1846	Transcriptional regulator
CXP43_RS04290	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CXP43_RS04290	COG0392	lysyltransferase activity
CXP43_RS04295	COG0384	phenazine biosynthesis protein PhzF
CXP43_RS04300	COG0778	Nitroreductase
CXP43_RS04315	COG1090	epimerase
CXP43_RS04330	COG2814	Major facilitator Superfamily
CXP43_RS04340	COG3591	Belongs to the peptidase S1B family
CXP43_RS04355	COG3103	Sh3 type 3 domain protein
CXP43_RS04360	COG5658	integral membrane protein
CXP43_RS04365	COG0596	Alpha beta hydrolase
CXP43_RS04370	COG0463	Glycosyl transferase, family 2
CXP43_RS04375	COG4485	Bacterial membrane protein, YfhO
CXP43_RS04380	COG1988	membrane-bound metal-dependent
CXP43_RS04385	COG1194	a g-specific adenine glycosylase
CXP43_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS04415	COG1132	(ABC) transporter
CXP43_RS04420	COG4129	membrane
CXP43_RS04430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CXP43_RS04435	COG0735	belongs to the Fur family
CXP43_RS04545	COG1757	Na H antiporter
CXP43_RS04550	COG3340	Belongs to the peptidase S51 family
CXP43_RS04560	COG0277	FAD linked oxidase domain protein
CXP43_RS04570	COG0747	negative chemotaxis
CXP43_RS04575	COG0601	transmembrane transport
CXP43_RS04580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXP43_RS04585	COG0444	Belongs to the ABC transporter superfamily
CXP43_RS04590	COG4608	Belongs to the ABC transporter superfamily
CXP43_RS04595	COG0753	catalase activity
CXP43_RS04605	COG1116	anion transmembrane transporter activity
CXP43_RS04610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CXP43_RS04615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXP43_RS04635	COG1476	TRANSCRIPTIONal
CXP43_RS04645	COG3382	B3 4 domain protein
CXP43_RS04650	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CXP43_RS04660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CXP43_RS04665	COG0789	Transcriptional regulator
CXP43_RS04670	COG1664	Polymer-forming cytoskeletal
CXP43_RS04675	COG1664	Polymer-forming cytoskeletal
CXP43_RS04685	COG2766	serine protein kinase
CXP43_RS04700	COG1846	Transcriptional regulator
CXP43_RS04705	COG1566	PFAM secretion protein HlyD family protein
CXP43_RS04710	COG2814	Major facilitator Superfamily
CXP43_RS04715	COG0655	NAD(P)H dehydrogenase (quinone) activity
CXP43_RS04730	COG1725	Transcriptional regulator
CXP43_RS04735	COG1131	(ABC) transporter
CXP43_RS04740	COG1131	(ABC) transporter
CXP43_RS04745	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CXP43_RS04750	COG1278	Cold shock
CXP43_RS04760	COG1464	Belongs to the NlpA lipoprotein family
CXP43_RS04765	COG3706	GGDEF domain
CXP43_RS04770	COG1823	symporter activity
CXP43_RS04790	COG5577	PFAM Coat F domain
CXP43_RS04795	COG0737	Belongs to the 5'-nucleotidase family
CXP43_RS04795	COG1525	nuclease
CXP43_RS04795	COG4085	toxin activity
CXP43_RS04800	COG3764	Sortase (surface protein transpeptidase)
CXP43_RS04805	COG0564	pseudouridine synthase activity
CXP43_RS04815	COG0517	IMP dehydrogenase activity
CXP43_RS04820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXP43_RS04825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXP43_RS04825	COG3153	acetyltransferase
CXP43_RS04830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXP43_RS04835	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CXP43_RS04840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CXP43_RS04850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXP43_RS04855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CXP43_RS04860	COG2203	Gaf domain
CXP43_RS04860	COG4585	Histidine kinase
CXP43_RS04865	COG2197	response regulator
CXP43_RS04870	COG0431	NADPH-dependent FMN reductase
CXP43_RS04885	COG1388	LysM domain
CXP43_RS04885	COG0791	NLP P60 protein
CXP43_RS04890	COG1959	2 iron, 2 sulfur cluster binding
CXP43_RS04895	COG0668	transmembrane transport
CXP43_RS04900	COG2719	SpoVR family
CXP43_RS04905	COG1785	Belongs to the alkaline phosphatase family
CXP43_RS04910	COG0791	NLP P60 protein
CXP43_RS04910	COG1388	LysM domain
CXP43_RS04915	COG0583	DNA-binding transcription factor activity
CXP43_RS04920	COG0372	Belongs to the citrate synthase family
CXP43_RS04925	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS04930	COG0531	amino acid
CXP43_RS04935	COG0733	neurotransmitter:sodium symporter activity
CXP43_RS04950	COG1595	DNA-templated transcription, initiation
CXP43_RS04955	COG0204	Acyl-transferase
CXP43_RS04960	COG1253	flavin adenine dinucleotide binding
CXP43_RS04965	COG0789	Transcriptional regulator
CXP43_RS04970	COG0436	Aminotransferase
CXP43_RS04975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXP43_RS04980	COG1253	flavin adenine dinucleotide binding
CXP43_RS04985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXP43_RS04990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXP43_RS04995	COG0584	glycerophosphoryl diester phosphodiesterase
CXP43_RS05005	COG0668	transmembrane transport
CXP43_RS05010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CXP43_RS05015	COG0726	polysaccharide deacetylase
CXP43_RS05020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXP43_RS05025	COG3226	Transcriptional regulator
CXP43_RS05035	COG0589	response to stress
CXP43_RS05040	COG1132	(ABC) transporter
CXP43_RS05045	COG1132	(ABC) transporter
CXP43_RS05050	COG0702	epimerase
CXP43_RS05070	COG0189	ligase activity
CXP43_RS05075	COG0189	ligase activity
CXP43_RS05090	COG4335	DNA alkylation repair
CXP43_RS05095	COG0561	phosphatase activity
CXP43_RS05100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXP43_RS05110	COG0475	glutathione-regulated potassium exporter activity
CXP43_RS05115	COG0490	domain, Protein
CXP43_RS05125	COG1024	Enoyl-CoA hydratase
CXP43_RS05135	COG4152	abc transporter atp-binding protein
CXP43_RS05140	COG1668	transmembrane transport
CXP43_RS05145	COG0420	3'-5' exonuclease activity
CXP43_RS05150	COG4717	serine-type aminopeptidase activity
CXP43_RS05165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXP43_RS05205	COG4980	gas vesicle protein
CXP43_RS05220	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CXP43_RS05225	COG0537	adenosine 5'-monophosphoramidase activity
CXP43_RS05230	COG1131	(ABC) transporter
CXP43_RS05235	COG4473	ABC transporter
CXP43_RS05245	COG1473	amidohydrolase
CXP43_RS05250	COG3069	C4-dicarboxylate transmembrane transporter activity
CXP43_RS05255	COG2329	Antibiotic biosynthesis monooxygenase
CXP43_RS05260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXP43_RS05270	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CXP43_RS05275	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CXP43_RS05280	COG1309	transcriptional regulator
CXP43_RS05285	COG1511	domain protein
CXP43_RS05290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXP43_RS05300	COG1363	Peptidase, m42
CXP43_RS05305	COG1301	dicarboxylic acid transport
CXP43_RS05315	COG1234	tRNA 3'-trailer cleavage
CXP43_RS05320	COG0095	Lipoate-protein ligase
CXP43_RS05325	COG0702	epimerase
CXP43_RS05330	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS05340	COG0501	Belongs to the peptidase M48B family
CXP43_RS05345	COG1404	Belongs to the peptidase S8 family
CXP43_RS05355	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CXP43_RS05360	COG0406	alpha-ribazole phosphatase activity
CXP43_RS05365	COG0183	Belongs to the thiolase family
CXP43_RS05370	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS05375	COG1268	BioY protein
CXP43_RS05380	COG0840	transmembrane signaling receptor activity
CXP43_RS05385	COG0723	plastoquinol--plastocyanin reductase activity
CXP43_RS05385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXP43_RS05390	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS05400	COG4903	ComK protein
CXP43_RS05405	COG5646	InterPro IPR014922
CXP43_RS05430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXP43_RS05445	COG0398	Pfam SNARE associated Golgi protein
CXP43_RS05450	COG0681	Belongs to the peptidase S26 family
CXP43_RS05455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXP43_RS05460	COG1846	Transcriptional regulator
CXP43_RS05465	COG3180	Ammonia monooxygenase
CXP43_RS05470	COG2814	Major facilitator Superfamily
CXP43_RS05480	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CXP43_RS05485	COG2323	membrane
CXP43_RS05500	COG0420	3'-5' exonuclease activity
CXP43_RS05505	COG0419	ATPase involved in DNA repair
CXP43_RS05510	COG1403	HNH endonuclease
CXP43_RS05550	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXP43_RS05565	COG0367	asparagine synthase
CXP43_RS05570	COG1562	ergosterol biosynthetic process
CXP43_RS05575	COG0534	Mate efflux family protein
CXP43_RS05580	COG1917	Cupin 2, conserved barrel domain protein
CXP43_RS05580	COG2207	Transcriptional regulator
CXP43_RS05585	COG1609	Transcriptional regulator
CXP43_RS05590	COG0673	inositol 2-dehydrogenase activity
CXP43_RS05595	COG2318	DinB family
CXP43_RS05600	COG1279	arginine transmembrane transporter activity
CXP43_RS05605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXP43_RS05610	COG1357	PFAM Pentapeptide repeats (8 copies)
CXP43_RS05615	COG2153	protein acetylation
CXP43_RS05620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CXP43_RS05620	COG0646	methionine synthase
CXP43_RS05630	COG2996	Protein conserved in bacteria
CXP43_RS05635	COG1744	ABC transporter substrate-binding protein PnrA-like
CXP43_RS05640	COG0840	transmembrane signaling receptor activity
CXP43_RS05645	COG2124	cytochrome p450
CXP43_RS05655	COG1307	EDD domain protein, DegV family
CXP43_RS05660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXP43_RS05675	COG0561	phosphatase activity
CXP43_RS05680	COG1073	alpha beta
CXP43_RS05685	COG2151	metal-sulfur cluster biosynthetic enzyme
CXP43_RS05695	COG0277	FAD linked oxidase domain protein
CXP43_RS05700	COG2271	Major facilitator Superfamily
CXP43_RS05710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CXP43_RS05720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXP43_RS05725	COG0505	Belongs to the CarA family
CXP43_RS05730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXP43_RS05735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CXP43_RS05755	COG2267	carboxylic ester hydrolase activity
CXP43_RS05765	COG1744	ABC transporter substrate-binding protein PnrA-like
CXP43_RS05780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXP43_RS05785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXP43_RS05790	COG5504	Zn-dependent protease
CXP43_RS05795	COG0444	Belongs to the ABC transporter superfamily
CXP43_RS05800	COG4608	Belongs to the ABC transporter superfamily
CXP43_RS05810	COG0601	transmembrane transport
CXP43_RS05815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXP43_RS05825	COG0180	Tryptophanyl-tRNA synthetase
CXP43_RS05830	COG4166	transmembrane transport
CXP43_RS05835	COG0601	transmembrane transport
CXP43_RS05840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXP43_RS05845	COG0444	Belongs to the ABC transporter superfamily
CXP43_RS05850	COG4608	Belongs to the ABC transporter superfamily
CXP43_RS05860	COG0456	acetyltransferase
CXP43_RS05865	COG1393	Belongs to the ArsC family
CXP43_RS05870	COG0861	Integral membrane protein TerC family
CXP43_RS05875	COG4862	establishment of competence for transformation
CXP43_RS05880	COG4469	Competence protein
CXP43_RS05885	COG1164	Oligoendopeptidase f
CXP43_RS05890	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CXP43_RS05895	COG2346	COG2346, Truncated hemoglobins
CXP43_RS05900	COG0741	lytic transglycosylase activity
CXP43_RS05905	COG4116	CYTH
CXP43_RS05915	COG2357	RelA SpoT domain protein
CXP43_RS05920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CXP43_RS05925	COG0564	pseudouridine synthase activity
CXP43_RS05940	COG0475	glutathione-regulated potassium exporter activity
CXP43_RS05940	COG0569	domain protein
CXP43_RS05945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CXP43_RS05950	COG0352	thiamine-phosphate diphosphorylase activity
CXP43_RS05955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXP43_RS05960	COG2104	thiamine diphosphate biosynthetic process
CXP43_RS05970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXP43_RS05975	COG0351	phosphomethylpyrimidine kinase
CXP43_RS05980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CXP43_RS06035	COG0210	DNA helicase
CXP43_RS06055	COG1131	(ABC) transporter
CXP43_RS06065	COG2153	protein acetylation
CXP43_RS06075	COG2382	esterase
CXP43_RS06080	COG0626	cystathionine gamma-synthase activity
CXP43_RS06085	COG0626	cystathionine gamma-synthase activity
CXP43_RS06115	COG5444	nuclease activity
CXP43_RS06135	COG0135	phosphoribosylanthranilate isomerase activity
CXP43_RS06145	COG0346	lactoylglutathione lyase activity
CXP43_RS06150	COG2367	Beta-lactamase
CXP43_RS06155	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXP43_RS06160	COG0477	Major facilitator Superfamily
CXP43_RS06165	COG1846	Transcriptional regulator
CXP43_RS06175	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CXP43_RS06180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXP43_RS06185	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CXP43_RS06190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXP43_RS06190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXP43_RS06195	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXP43_RS06225	COG1285	pathogenesis
CXP43_RS06240	COG2205	protein histidine kinase activity
CXP43_RS06250	COG3383	formate dehydrogenase (NAD+) activity
CXP43_RS06255	COG2427	Protein of unknown function (DUF1641)
CXP43_RS06260	COG2124	cytochrome p450
CXP43_RS06265	COG1819	glycosyl
CXP43_RS06275	COG1587	Uroporphyrinogen-III synthase
CXP43_RS06280	COG0390	transport system, permease component
CXP43_RS06285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXP43_RS06290	COG0697	spore germination
CXP43_RS06295	COG4297	protein containing double-stranded beta helix domain
CXP43_RS06305	COG1252	NADH dehydrogenase
CXP43_RS06315	COG2211	Major facilitator Superfamily
CXP43_RS06320	COG1609	Transcriptional regulator
CXP43_RS06325	COG0246	Mannitol dehydrogenase
CXP43_RS06330	COG2721	sulfolactate sulfo-lyase activity
CXP43_RS06335	COG0730	response to heat
CXP43_RS06340	COG2318	DinB family
CXP43_RS06345	COG0457	Tetratricopeptide repeat
CXP43_RS06350	COG3409	Peptidoglycan-binding domain 1 protein
CXP43_RS06350	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS06350	COG1388	LysM domain
CXP43_RS06360	COG4195	phage-related replication protein
CXP43_RS06365	COG2856	Zn peptidase
CXP43_RS06375	COG1396	sequence-specific DNA binding
CXP43_RS06385	COG1522	sequence-specific DNA binding
CXP43_RS06390	COG1484	DNA-dependent DNA replication
CXP43_RS06405	COG1595	DNA-templated transcription, initiation
CXP43_RS06410	COG4193	domain, Protein
CXP43_RS06445	COG3409	Peptidoglycan-binding domain 1 protein
CXP43_RS06445	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS06460	COG0306	phosphate transporter
CXP43_RS06465	COG1392	Phosphate transport regulator
CXP43_RS06470	COG0531	amino acid
CXP43_RS06475	COG0346	lactoylglutathione lyase activity
CXP43_RS06480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CXP43_RS06485	COG0463	Glycosyl transferase, family 2
CXP43_RS06490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXP43_RS06495	COG0477	Major facilitator Superfamily
CXP43_RS06500	COG2362	D-Aminopeptidase
CXP43_RS06505	COG0601	transmembrane transport
CXP43_RS06510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXP43_RS06515	COG0444	Belongs to the ABC transporter superfamily
CXP43_RS06520	COG4166	transmembrane transport
CXP43_RS06525	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXP43_RS06530	COG4948	Mandelate Racemase Muconate Lactonizing
CXP43_RS06535	COG0791	NLP P60 protein
CXP43_RS06540	COG4608	Belongs to the ABC transporter superfamily
CXP43_RS06545	COG2706	6-phosphogluconolactonase activity
CXP43_RS06550	COG1834	amidinotransferase
CXP43_RS06555	COG1607	acyl-coa hydrolase
CXP43_RS06560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXP43_RS06565	COG2076	Multidrug Resistance protein
CXP43_RS06570	COG2076	Multidrug Resistance protein
CXP43_RS06575	COG0788	formyltetrahydrofolate deformylase activity
CXP43_RS06580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CXP43_RS06590	COG1764	response to oxidative stress
CXP43_RS06595	COG1846	Transcriptional regulator
CXP43_RS06600	COG1764	response to oxidative stress
CXP43_RS06615	COG0463	Glycosyl transferase, family 2
CXP43_RS06615	COG0457	Tetratricopeptide repeat
CXP43_RS06625	COG2814	Major facilitator Superfamily
CXP43_RS06630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXP43_RS06640	COG1404	Belongs to the peptidase S8 family
CXP43_RS06645	COG1366	Belongs to the anti-sigma-factor antagonist family
CXP43_RS06650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CXP43_RS06655	COG1122	ATPase activity
CXP43_RS06660	COG4721	ABC-type cobalt transport system, permease component
CXP43_RS06665	COG1388	LysM domain
CXP43_RS06665	COG3858	chitin binding
CXP43_RS06680	COG2239	Acts as a magnesium transporter
CXP43_RS06685	COG0789	Transcriptional regulator
CXP43_RS06700	COG1846	Transcriptional regulator
CXP43_RS06705	COG0726	polysaccharide deacetylase
CXP43_RS06710	COG3285	dna ligase
CXP43_RS06710	COG1793	dna ligase
CXP43_RS06715	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CXP43_RS06725	COG0586	Pfam SNARE associated Golgi protein
CXP43_RS06730	COG0861	Integral membrane protein TerC family
CXP43_RS06735	COG1191	sigma factor activity
CXP43_RS06760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CXP43_RS06765	COG2323	membrane
CXP43_RS06775	COG3594	Acyltransferase
CXP43_RS06780	COG5002	protein histidine kinase activity
CXP43_RS06785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXP43_RS06800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXP43_RS06805	COG0436	Aminotransferase
CXP43_RS06835	COG3852	Histidine kinase
CXP43_RS06840	COG1846	Transcriptional regulator
CXP43_RS06845	COG1360	Flagellar Motor Protein
CXP43_RS06850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXP43_RS06855	COG0542	response to heat
CXP43_RS06865	COG3949	Membrane
CXP43_RS06880	COG0720	synthase
CXP43_RS06885	COG0602	queuosine metabolic process
CXP43_RS06895	COG1733	regulation of RNA biosynthetic process
CXP43_RS06900	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS06915	COG4873	Protein conserved in bacteria
CXP43_RS06925	COG3773	Cell wall hydrolase
CXP43_RS06930	COG2244	polysaccharide biosynthetic process
CXP43_RS06935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXP43_RS06940	COG2217	Heavy metal translocating P-type atpase
CXP43_RS06945	COG0006	proline dipeptidase activity
CXP43_RS06950	COG1609	Transcriptional regulator
CXP43_RS06955	COG3711	transcriptional antiterminator
CXP43_RS06960	COG1263	PTS System
CXP43_RS06960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXP43_RS06960	COG2190	(PTS) system
CXP43_RS06965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXP43_RS06970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXP43_RS06980	COG1533	DNA photolyase activity
CXP43_RS06985	COG0840	transmembrane signaling receptor activity
CXP43_RS06990	COG2084	Dehydrogenase
CXP43_RS07000	COG2340	Cysteine-rich secretory protein family
CXP43_RS07005	COG0768	penicillin binding
CXP43_RS07010	COG4191	Histidine kinase
CXP43_RS07015	COG0436	Aminotransferase
CXP43_RS07025	COG0784	Response regulator, receiver
CXP43_RS07025	COG0835	chemotaxis
CXP43_RS07035	COG2814	Major facilitator Superfamily
CXP43_RS07040	COG1376	ErfK ybiS ycfS ynhG family protein
CXP43_RS07045	COG1408	metallophosphoesterase
CXP43_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS07060	COG2200	EAL domain
CXP43_RS07070	COG4703	Protein of unknown function (DUF1797)
CXP43_RS07075	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CXP43_RS07085	COG0517	IMP dehydrogenase activity
CXP43_RS07090	COG0583	DNA-binding transcription factor activity
CXP43_RS07095	COG0716	FMN binding
CXP43_RS07105	COG0716	FMN binding
CXP43_RS07125	COG0668	transmembrane transport
CXP43_RS07130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXP43_RS07150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXP43_RS07155	COG0303	'Molybdopterin
CXP43_RS07160	COG1763	Mo-molybdopterin cofactor biosynthetic process
CXP43_RS07165	COG0314	molybdopterin synthase activity
CXP43_RS07170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CXP43_RS07180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXP43_RS07185	COG1136	(ABC) transporter
CXP43_RS07190	COG0577	efflux transmembrane transporter activity
CXP43_RS07195	COG1349	DNA-binding transcription factor activity
CXP43_RS07200	COG1105	Belongs to the carbohydrate kinase PfkB family
CXP43_RS07205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXP43_RS07205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXP43_RS07205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXP43_RS07210	COG0681	Belongs to the peptidase S26 family
CXP43_RS07220	COG0488	(ABC) transporter
CXP43_RS07225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CXP43_RS07230	COG2309	aminopeptidase activity
CXP43_RS07240	COG1077	Cell shape determining protein MreB Mrl
CXP43_RS07250	COG2002	toxin-antitoxin pair type II binding
CXP43_RS07255	COG3852	Histidine kinase
CXP43_RS07260	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CXP43_RS07260	COG2105	PFAM AIG2 family protein
CXP43_RS07265	COG0569	domain protein
CXP43_RS07275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CXP43_RS07285	COG0561	phosphatase activity
CXP43_RS07290	COG0242	peptide deformylase activity
CXP43_RS07300	COG0497	DNA recombination
CXP43_RS07315	COG4221	oxidoreductase activity
CXP43_RS07315	COG3321	synthase
CXP43_RS07315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS07315	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS07320	COG3321	synthase
CXP43_RS07320	COG0300	oxidoreductase activity
CXP43_RS07320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS07320	COG4221	oxidoreductase activity
CXP43_RS07325	COG4221	oxidoreductase activity
CXP43_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS07325	COG3321	synthase
CXP43_RS07325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS07330	COG0300	oxidoreductase activity
CXP43_RS07330	COG4221	oxidoreductase activity
CXP43_RS07330	COG3321	synthase
CXP43_RS07330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS07335	COG4221	oxidoreductase activity
CXP43_RS07335	COG3321	synthase
CXP43_RS07335	COG0300	oxidoreductase activity
CXP43_RS07335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS07340	COG4221	oxidoreductase activity
CXP43_RS07340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS07340	COG0300	oxidoreductase activity
CXP43_RS07340	COG3321	synthase
CXP43_RS07345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS07345	COG3321	synthase
CXP43_RS07345	COG4221	oxidoreductase activity
CXP43_RS07350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXP43_RS07355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CXP43_RS07360	COG0022	dehydrogenase e1 component
CXP43_RS07365	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXP43_RS07370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXP43_RS07375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXP43_RS07390	COG1982	Orn Lys Arg decarboxylase major
CXP43_RS07415	COG0483	inositol monophosphate 1-phosphatase activity
CXP43_RS07425	COG3227	Zinc metalloprotease (Elastase)
CXP43_RS07450	COG1217	gtp-binding protein TYPA
CXP43_RS07460	COG4896	Protein conserved in bacteria
CXP43_RS07470	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CXP43_RS07475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CXP43_RS07560	COG0457	Tetratricopeptide repeat
CXP43_RS07575	COG2433	Pfam Transposase IS66
CXP43_RS07585	COG0739	heme binding
CXP43_RS07585	COG1196	nuclear chromosome segregation
CXP43_RS07585	COG0741	lytic transglycosylase activity
CXP43_RS07705	COG2066	Belongs to the glutaminase family
CXP43_RS07715	COG0772	Belongs to the SEDS family
CXP43_RS07720	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CXP43_RS07735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CXP43_RS07735	COG2010	Cytochrome c
CXP43_RS07740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXP43_RS07745	COG1845	cytochrome c oxidase, subunit III
CXP43_RS07750	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CXP43_RS07755	COG3336	cytochrome c oxidase
CXP43_RS07765	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CXP43_RS07770	COG2340	Cysteine-rich secretory protein family
CXP43_RS07785	COG3679	Belongs to the UPF0342 family
CXP43_RS07800	COG0742	ribosomal rna small subunit methyltransferase
CXP43_RS07810	COG3314	Sporulation integral membrane protein YlbJ
CXP43_RS07815	COG1752	Esterase of the alpha-beta hydrolase superfamily
CXP43_RS07820	COG3480	Lon protease (S16) C-terminal proteolytic domain
CXP43_RS07830	COG1399	metal-binding, possibly nucleic acid-binding protein
CXP43_RS07850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CXP43_RS07870	COG4839	cell division protein FtsL
CXP43_RS07875	COG0768	penicillin binding
CXP43_RS07880	COG0768	penicillin binding
CXP43_RS07900	COG0772	Belongs to the SEDS family
CXP43_RS07915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CXP43_RS07920	COG0849	cell division
CXP43_RS07925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXP43_RS07930	COG4412	M6 family metalloprotease domain protein
CXP43_RS07930	COG1404	Belongs to the peptidase S8 family
CXP43_RS07940	COG1191	sigma factor activity
CXP43_RS07945	COG1191	sigma factor activity
CXP43_RS07950	COG1119	ATPase activity
CXP43_RS07955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXP43_RS07960	COG1873	PFAM PRC-barrel domain
CXP43_RS07965	COG1496	oxidoreductase activity
CXP43_RS07970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CXP43_RS07980	COG0762	integral membrane protein
CXP43_RS07985	COG2302	S4 RNA-binding domain
CXP43_RS07990	COG3599	regulation of cell shape
CXP43_RS08000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CXP43_RS08005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXP43_RS08015	COG0564	pseudouridine synthase activity
CXP43_RS08025	COG2233	PERMEase
CXP43_RS08035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CXP43_RS08040	COG0505	Belongs to the CarA family
CXP43_RS08045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXP43_RS08060	COG0284	orotidine-5'-phosphate decarboxylase activity
CXP43_RS08065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CXP43_RS08075	COG0306	phosphate transporter
CXP43_RS08090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CXP43_RS08095	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CXP43_RS08100	COG1648	precorrin-2 dehydrogenase activity
CXP43_RS08115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXP43_RS08120	COG1561	YicC-like family, N-terminal region
CXP43_RS08130	COG0194	GDP metabolic process
CXP43_RS08140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXP43_RS08145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXP43_RS08150	COG0242	peptide deformylase activity
CXP43_RS08160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CXP43_RS08160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CXP43_RS08170	COG0631	protein serine/threonine phosphatase activity
CXP43_RS08175	COG2815	serine threonine protein kinase
CXP43_RS08175	COG0515	serine threonine protein kinase
CXP43_RS08185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXP43_RS08190	COG1564	THIamine pyrophosphokinase
CXP43_RS08205	COG1302	Protein conserved in bacteria
CXP43_RS08210	COG1461	Dihydroxyacetone kinase
CXP43_RS08215	COG1760	l-serine dehydratase
CXP43_RS08220	COG1760	l-serine dehydratase
CXP43_RS08225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXP43_RS08240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXP43_RS08245	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS08260	COG1196	nuclear chromosome segregation
CXP43_RS08265	COG0552	protein localization to endoplasmic reticulum
CXP43_RS08280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXP43_RS08290	COG1837	Belongs to the UPF0109 family
CXP43_RS08315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CXP43_RS08330	COG2257	FlhB HrpN YscU SpaS Family
CXP43_RS08340	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXP43_RS08345	COG0758	DNA mediated transformation
CXP43_RS08350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXP43_RS08360	COG4974	Belongs to the 'phage' integrase family
CXP43_RS08380	COG1815	bacterial-type flagellum-dependent cell motility
CXP43_RS08385	COG1558	bacterial-type flagellum-dependent cell motility
CXP43_RS08390	COG1677	Flagellar hook-basal body complex protein FliE
CXP43_RS08395	COG1766	The M ring may be actively involved in energy transduction
CXP43_RS08400	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXP43_RS08405	COG1317	bacterial-type flagellum organization
CXP43_RS08410	COG1157	protein secretion by the type III secretion system
CXP43_RS08415	COG2882	bacterial-type flagellum organization
CXP43_RS08420	COG3334	PFAM MgtE intracellular
CXP43_RS08425	COG3144	bacterial-type flagellum assembly
CXP43_RS08430	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CXP43_RS08435	COG4786	Flagellar basal body rod
CXP43_RS08440	COG1582	Flagellar protein (FlbD)
CXP43_RS08445	COG1580	Controls the rotational direction of flagella during chemotaxis
CXP43_RS08450	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXP43_RS08455	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXP43_RS08455	COG1776	CheC inhibitor of MCP methylation
CXP43_RS08460	COG2201	protein-glutamate methylesterase activity
CXP43_RS08465	COG3190	flagellar
CXP43_RS08470	COG1338	Plays a role in the flagellum-specific transport system
CXP43_RS08475	COG1987	bacterial-type flagellum assembly
CXP43_RS08480	COG1684	flagellar biosynthetic protein fliR
CXP43_RS08485	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXP43_RS08490	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXP43_RS08495	COG1419	protein localization to endoplasmic reticulum
CXP43_RS08500	COG0455	bacterial-type flagellum organization
CXP43_RS08505	COG2201	protein-glutamate methylesterase activity
CXP43_RS08510	COG2198	Histidine kinase
CXP43_RS08510	COG0643	Histidine kinase
CXP43_RS08515	COG0835	chemotaxis
CXP43_RS08520	COG1776	CheC inhibitor of MCP methylation
CXP43_RS08530	COG1191	sigma factor activity
CXP43_RS08560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CXP43_RS08565	COG4589	Belongs to the CDS family
CXP43_RS08575	COG0750	zinc metalloprotease
CXP43_RS08585	COG2176	DNA-directed DNA polymerase activity
CXP43_RS08595	COG0195	Participates in both transcription termination and antitermination
CXP43_RS08600	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CXP43_RS08605	COG1358	cellular component organization or biogenesis
CXP43_RS08615	COG1550	Protein conserved in bacteria
CXP43_RS08630	COG0196	riboflavin kinase activity
CXP43_RS08645	COG0726	polysaccharide deacetylase
CXP43_RS08650	COG0612	Peptidase, M16
CXP43_RS08655	COG1873	PFAM PRC-barrel domain
CXP43_RS08660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXP43_RS08665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXP43_RS08670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXP43_RS08675	COG0527	aspartate kinase activity
CXP43_RS08685	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CXP43_RS08690	COG0740	serine-type endopeptidase activity
CXP43_RS08700	COG4980	gas vesicle protein
CXP43_RS08700	COG1674	ftsk spoiiie
CXP43_RS08705	COG2188	Transcriptional regulator
CXP43_RS08710	COG2814	Major facilitator Superfamily
CXP43_RS08715	COG1846	Transcriptional regulator
CXP43_RS08720	COG2409	Drug exporters of the RND superfamily
CXP43_RS08720	COG1033	growth of symbiont in host cell
CXP43_RS08725	COG0612	Peptidase, M16
CXP43_RS08730	COG0612	Peptidase, M16
CXP43_RS08735	COG0300	oxidoreductase activity
CXP43_RS08750	COG1426	Protein conserved in bacteria
CXP43_RS08755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXP43_RS08770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXP43_RS08780	COG1692	metallophosphoesterase
CXP43_RS08785	COG2359	stage V sporulation protein S
CXP43_RS08805	COG4550	Control of competence regulator ComK, YlbF/YmcA
CXP43_RS08880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS08885	COG3425	synthase
CXP43_RS08890	COG1024	Enoyl-CoA hydratase
CXP43_RS08895	COG1024	Enoyl-CoA hydratase
CXP43_RS08900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS08900	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS08900	COG0300	oxidoreductase activity
CXP43_RS08900	COG3321	synthase
CXP43_RS08900	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS08905	COG3321	synthase
CXP43_RS08905	COG4221	oxidoreductase activity
CXP43_RS08905	COG0300	oxidoreductase activity
CXP43_RS08905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS08910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS08910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXP43_RS08910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXP43_RS08910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS08910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS08910	COG3321	synthase
CXP43_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS08910	COG3321	synthase
CXP43_RS08910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS08915	COG4221	oxidoreductase activity
CXP43_RS08915	COG3321	synthase
CXP43_RS08915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS08920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS08920	COG3321	synthase
CXP43_RS08920	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CXP43_RS08920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CXP43_RS08935	COG3619	membrane
CXP43_RS08945	COG1404	Belongs to the peptidase S8 family
CXP43_RS08955	COG4195	phage-related replication protein
CXP43_RS08960	COG1764	response to oxidative stress
CXP43_RS08970	COG2076	Multidrug Resistance protein
CXP43_RS09010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXP43_RS09015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXP43_RS09020	COG4112	unkown
CXP43_RS09025	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS09035	COG0464	growth
CXP43_RS09040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CXP43_RS09045	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CXP43_RS09050	COG0789	Transcriptional regulator
CXP43_RS09055	COG0174	glutamine synthetase
CXP43_RS09060	COG0582	viral genome integration into host DNA
CXP43_RS09070	COG1525	nuclease
CXP43_RS09075	COG5444	nuclease activity
CXP43_RS09115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXP43_RS09120	COG0457	Tetratricopeptide repeat
CXP43_RS09145	COG3409	Peptidoglycan-binding domain 1 protein
CXP43_RS09145	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS09150	COG5434	Belongs to the glycosyl hydrolase 28 family
CXP43_RS09160	COG2433	Pfam Transposase IS66
CXP43_RS09170	COG0739	heme binding
CXP43_RS09170	COG1196	nuclear chromosome segregation
CXP43_RS09170	COG0741	lytic transglycosylase activity
CXP43_RS09335	COG0776	regulation of translation
CXP43_RS09445	COG3655	Transcriptional regulator
CXP43_RS09450	COG3655	Transcriptional regulator
CXP43_RS09540	COG3655	Transcriptional regulator
CXP43_RS09635	COG1793	dna ligase
CXP43_RS09640	COG2135	peptidase activity
CXP43_RS09655	COG4195	phage-related replication protein
CXP43_RS09660	COG5434	Belongs to the glycosyl hydrolase 28 family
CXP43_RS09660	COG3420	alginic acid biosynthetic process
CXP43_RS09685	COG2887	Belongs to the helicase family. UvrD subfamily
CXP43_RS09695	COG0305	Participates in initiation and elongation during chromosome replication
CXP43_RS09700	COG0358	DNA primase activity
CXP43_RS09705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXP43_RS09710	COG0587	DNA-directed DNA polymerase activity
CXP43_RS09715	COG3584	3D domain protein
CXP43_RS09725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXP43_RS09850	COG1780	Probably involved in ribonucleotide reductase function
CXP43_RS09855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXP43_RS09855	COG1372	Participates in initiation and elongation during chromosome replication
CXP43_RS09865	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXP43_RS09870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXP43_RS09885	COG0756	dUTP diphosphatase activity
CXP43_RS09905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CXP43_RS09945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXP43_RS09995	COG3331	DNA recombination
CXP43_RS10035	COG2211	Major facilitator Superfamily
CXP43_RS10040	COG3507	Belongs to the glycosyl hydrolase 43 family
CXP43_RS10055	COG1070	Carbohydrate kinase
CXP43_RS10060	COG3848	Pyruvate phosphate dikinase
CXP43_RS10060	COG0574	Belongs to the PEP-utilizing enzyme family
CXP43_RS10085	COG2378	regulation of single-species biofilm formation
CXP43_RS10090	COG2318	DinB family
CXP43_RS10095	COG1064	alcohol dehydrogenase
CXP43_RS10120	COG0456	acetyltransferase
CXP43_RS10125	COG5444	nuclease activity
CXP43_RS10185	COG3397	chitin binding
CXP43_RS10195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXP43_RS10205	COG5434	Belongs to the glycosyl hydrolase 28 family
CXP43_RS10215	COG0756	dUTP diphosphatase activity
CXP43_RS10220	COG4195	phage-related replication protein
CXP43_RS10250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXP43_RS10260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXP43_RS10280	COG0785	Cytochrome C biogenesis protein
CXP43_RS10285	COG2201	protein-glutamate methylesterase activity
CXP43_RS10290	COG4846	Membrane protein involved in cytochrome C biogenesis
CXP43_RS10300	COG0071	Belongs to the small heat shock protein (HSP20) family
CXP43_RS10315	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CXP43_RS10320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXP43_RS10340	COG0824	Thioesterase
CXP43_RS10350	COG4841	protein insertion into membrane
CXP43_RS10360	COG1832	CoA-binding protein
CXP43_RS10365	COG0187	DNA topoisomerase II activity
CXP43_RS10370	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXP43_RS10380	COG1115	amino acid carrier protein
CXP43_RS10390	COG1063	alcohol dehydrogenase
CXP43_RS10395	COG0800	Aldolase
CXP43_RS10400	COG1312	Catalyzes the dehydration of D-mannonate
CXP43_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS10410	COG1609	Transcriptional regulator
CXP43_RS10415	COG2271	Major facilitator Superfamily
CXP43_RS10460	COG2205	protein histidine kinase activity
CXP43_RS10465	COG0745	RESPONSE REGULATOR receiver
CXP43_RS10475	COG3507	Belongs to the glycosyl hydrolase 43 family
CXP43_RS10500	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS10505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CXP43_RS10510	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CXP43_RS10515	COG2610	gluconate transmembrane transporter activity
CXP43_RS10520	COG2124	cytochrome p450
CXP43_RS10540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXP43_RS10550	COG2246	polysaccharide biosynthetic process
CXP43_RS10555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXP43_RS10560	COG0586	Pfam SNARE associated Golgi protein
CXP43_RS10565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CXP43_RS10570	COG1024	Enoyl-CoA hydratase
CXP43_RS10575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CXP43_RS10580	COG0511	ligase activity, forming carbon-carbon bonds
CXP43_RS10585	COG0439	Biotin carboxylase
CXP43_RS10590	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS10595	COG1960	acyl-CoA dehydrogenase activity
CXP43_RS10600	COG1649	PFAM Uncharacterised BCR, COG1649
CXP43_RS10610	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CXP43_RS10610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS10615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS10620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS10625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS10630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS10640	COG2027	D-alanyl-D-alanine carboxypeptidase
CXP43_RS10645	COG2017	converts alpha-aldose to the beta-anomer
CXP43_RS10650	COG0534	Mate efflux family protein
CXP43_RS10665	COG0582	viral genome integration into host DNA
CXP43_RS10670	COG0166	Belongs to the GPI family
CXP43_RS10675	COG0405	Gamma-glutamyltransferase
CXP43_RS10680	COG2814	Major facilitator Superfamily
CXP43_RS10685	COG0640	Transcriptional regulator
CXP43_RS10690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CXP43_RS10700	COG0604	alcohol dehydrogenase
CXP43_RS10710	COG0493	'glutamate synthase
CXP43_RS10715	COG0067	glutamate synthase
CXP43_RS10715	COG0069	glutamate synthase activity
CXP43_RS10715	COG0070	glutamate synthase
CXP43_RS10720	COG0583	DNA-binding transcription factor activity
CXP43_RS10725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CXP43_RS10740	COG0300	oxidoreductase activity
CXP43_RS10745	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CXP43_RS10755	COG2814	Major facilitator Superfamily
CXP43_RS10760	COG1070	Carbohydrate kinase
CXP43_RS10765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXP43_RS10770	COG0243	molybdopterin cofactor binding
CXP43_RS10800	COG5444	nuclease activity
CXP43_RS10805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXP43_RS10810	COG0662	Cupin 2, conserved barrel domain protein
CXP43_RS10810	COG2207	Transcriptional regulator
CXP43_RS10815	COG1309	transcriptional regulator
CXP43_RS10820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXP43_RS10830	COG0640	Transcriptional regulator
CXP43_RS10835	COG0741	lytic transglycosylase activity
CXP43_RS10840	COG2322	membrane
CXP43_RS10855	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXP43_RS10865	COG1388	LysM domain
CXP43_RS10865	COG3584	3D domain protein
CXP43_RS10870	COG0514	ATP-dependent DNA helicase (RecQ)
CXP43_RS10880	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CXP43_RS10885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXP43_RS10900	COG0071	Belongs to the small heat shock protein (HSP20) family
CXP43_RS10935	COG1012	belongs to the aldehyde dehydrogenase family
CXP43_RS10940	COG1657	PFAM Prenyltransferase squalene oxidase
CXP43_RS10945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXP43_RS10950	COG0733	neurotransmitter:sodium symporter activity
CXP43_RS10955	COG0385	Bile acid
CXP43_RS10960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXP43_RS10965	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXP43_RS10980	COG4548	von Willebrand factor, type A
CXP43_RS10985	COG0714	Associated with various cellular activities
CXP43_RS10990	COG2032	superoxide dismutase activity
CXP43_RS10995	COG1388	LysM domain
CXP43_RS10995	COG0791	NLP P60 protein
CXP43_RS11000	COG1819	glycosyl
CXP43_RS11005	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CXP43_RS11010	COG0534	Mate efflux family protein
CXP43_RS11015	COG1366	Belongs to the anti-sigma-factor antagonist family
CXP43_RS11020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXP43_RS11025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXP43_RS11035	COG2962	Rard protein
CXP43_RS11050	COG1942	4-Oxalocrotonate Tautomerase
CXP43_RS11060	COG1733	regulation of RNA biosynthetic process
CXP43_RS11065	COG0778	Nitroreductase
CXP43_RS11070	COG0400	carboxylic ester hydrolase activity
CXP43_RS11075	COG0346	lactoylglutathione lyase activity
CXP43_RS11085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXP43_RS11095	COG2723	6-phospho-beta-galactosidase activity
CXP43_RS11100	COG2188	Transcriptional regulator
CXP43_RS11105	COG0793	Belongs to the peptidase S41A family
CXP43_RS11105	COG3409	Peptidoglycan-binding domain 1 protein
CXP43_RS11110	COG2226	methyltransferase
CXP43_RS11120	COG1876	peptidase activity
CXP43_RS11140	COG0671	phosphoesterase, PA-phosphatase related
CXP43_RS11170	COG1509	lysine 2,3-aminomutase activity
CXP43_RS11175	COG0456	acetyltransferase
CXP43_RS11180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXP43_RS11185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CXP43_RS11190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CXP43_RS11195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXP43_RS11200	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXP43_RS11210	COG0456	acetyltransferase
CXP43_RS11215	COG0463	Glycosyl transferase, family 2
CXP43_RS11230	COG4641	Protein conserved in bacteria
CXP43_RS11240	COG1086	Polysaccharide biosynthesis protein
CXP43_RS11255	COG1846	Transcriptional regulator
CXP43_RS11260	COG4698	Protein conserved in bacteria
CXP43_RS11265	COG2755	lipolytic protein G-D-S-L family
CXP43_RS11270	COG1999	signal sequence binding
CXP43_RS11280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXP43_RS11285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CXP43_RS11290	COG1272	protein, Hemolysin III
CXP43_RS11295	COG0204	Acyl-transferase
CXP43_RS11300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXP43_RS11315	COG2521	methyltransferase
CXP43_RS11315	COG2136	Putative SAM-dependent methyltransferase
CXP43_RS11330	COG1413	lyase activity
CXP43_RS11335	COG1418	mRNA catabolic process
CXP43_RS11340	COG0386	Belongs to the glutathione peroxidase family
CXP43_RS11350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CXP43_RS11355	COG1278	Cold shock
CXP43_RS11375	COG0328	RNA-DNA hybrid ribonuclease activity
CXP43_RS11380	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CXP43_RS11385	COG0328	RNA-DNA hybrid ribonuclease activity
CXP43_RS11395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXP43_RS11410	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CXP43_RS11420	COG1755	Isoprenylcysteine carboxyl methyltransferase
CXP43_RS11425	COG3424	synthase
CXP43_RS11450	COG1335	isochorismatase
CXP43_RS11490	COG4824	toxin secretion phage lysis holin
CXP43_RS11510	COG5434	Belongs to the glycosyl hydrolase 28 family
CXP43_RS11515	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXP43_RS11525	COG5280	Phage tail tape measure protein TP901
CXP43_RS11525	COG3953	SLT domain
CXP43_RS11630	COG1595	DNA-templated transcription, initiation
CXP43_RS11655	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CXP43_RS11660	COG1484	DNA-dependent DNA replication
CXP43_RS11665	COG3935	DnaD domain protein
CXP43_RS11705	COG3646	Phage regulatory protein
CXP43_RS11705	COG3645	SOS response
CXP43_RS11720	COG3620	sequence-specific DNA binding
CXP43_RS11725	COG0582	viral genome integration into host DNA
CXP43_RS11730	COG2233	PERMEase
CXP43_RS11740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CXP43_RS11745	COG1199	ATP-dependent helicase activity
CXP43_RS11760	COG0116	Belongs to the methyltransferase superfamily
CXP43_RS11785	COG3359	exonuclease
CXP43_RS11790	COG1205	dead DEAH box helicase
CXP43_RS11790	COG1111	helicase
CXP43_RS11795	COG2190	(PTS) system
CXP43_RS11800	COG0071	Belongs to the small heat shock protein (HSP20) family
CXP43_RS11840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXP43_RS11840	COG4499	WXG100 protein secretion system (Wss), protein YukC
CXP43_RS11850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CXP43_RS11855	COG3935	DnaD domain protein
CXP43_RS11865	COG0436	Aminotransferase
CXP43_RS11870	COG5353	protein conserved in bacteria
CXP43_RS11880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXP43_RS11880	COG1199	ATP-dependent helicase activity
CXP43_RS11910	COG0438	transferase activity, transferring glycosyl groups
CXP43_RS11915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXP43_RS11930	COG1694	Mazg nucleotide pyrophosphohydrolase
CXP43_RS11935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXP43_RS11940	COG2140	Oxalate decarboxylase
CXP43_RS11950	COG4347	Protein of unknown function (DUF1405)
CXP43_RS11955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CXP43_RS11955	COG2010	Cytochrome c
CXP43_RS11960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CXP43_RS11965	COG0723	plastoquinol--plastocyanin reductase activity
CXP43_RS11980	COG0457	Tetratricopeptide repeat
CXP43_RS11990	COG0287	Prephenate dehydrogenase
CXP43_RS12025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXP43_RS12030	COG4401	Chorismate mutase type I
CXP43_RS12045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CXP43_RS12050	COG0105	UTP biosynthetic process
CXP43_RS12055	COG0142	geranyltranstransferase activity
CXP43_RS12065	COG0142	geranyltranstransferase activity
CXP43_RS12080	COG0776	regulation of translation
CXP43_RS12085	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CXP43_RS12125	COG0539	negative regulation of cytoplasmic translation
CXP43_RS12135	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CXP43_RS12140	COG2959	enzyme of heme biosynthesis
CXP43_RS12145	COG3773	Cell wall hydrolase
CXP43_RS12145	COG3409	Peptidoglycan-binding domain 1 protein
CXP43_RS12150	COG2339	peptidase activity
CXP43_RS12155	COG0492	ferredoxin-NADP+ reductase activity
CXP43_RS12160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXP43_RS12165	COG4862	establishment of competence for transformation
CXP43_RS12170	COG1408	metallophosphoesterase
CXP43_RS12180	COG1388	LysM domain
CXP43_RS12185	COG1266	CAAX protease self-immunity
CXP43_RS12190	COG0514	ATP-dependent DNA helicase (RecQ)
CXP43_RS12195	COG4955	Helix-turn-helix domain
CXP43_RS12200	COG1141	Ferredoxin
CXP43_RS12205	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CXP43_RS12210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXP43_RS12220	COG1595	DNA-templated transcription, initiation
CXP43_RS12225	COG5002	protein histidine kinase activity
CXP43_RS12230	COG0745	RESPONSE REGULATOR receiver
CXP43_RS12235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXP43_RS12240	COG1333	cytochrome c biogenesis protein
CXP43_RS12245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXP43_RS12250	COG1187	pseudouridine synthase activity
CXP43_RS12255	COG0700	Nucleoside recognition
CXP43_RS12260	COG2715	membrane protein required for spore maturation
CXP43_RS12265	COG1686	Belongs to the peptidase S11 family
CXP43_RS12290	COG1547	Domain of unknown function (DUF309)
CXP43_RS12300	COG0456	acetyltransferase
CXP43_RS12315	COG0307	riboflavin synthase, alpha
CXP43_RS12320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXP43_RS12320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXP43_RS12330	COG0681	Belongs to the peptidase S26 family
CXP43_RS12340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXP43_RS12345	COG4086	secreted protein
CXP43_RS12350	COG0019	diaminopimelate decarboxylase activity
CXP43_RS12355	COG0697	spore germination
CXP43_RS12370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXP43_RS12390	COG1191	sigma factor activity
CXP43_RS12400	COG1366	Belongs to the anti-sigma-factor antagonist family
CXP43_RS12405	COG1686	Belongs to the peptidase S11 family
CXP43_RS12410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CXP43_RS12415	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CXP43_RS12420	COG4974	Belongs to the 'phage' integrase family
CXP43_RS12430	COG0735	belongs to the Fur family
CXP43_RS12435	COG1300	Membrane
CXP43_RS12450	COG0281	malic enzyme
CXP43_RS12455	COG1757	Na H antiporter
CXP43_RS12460	COG1027	Aspartate ammonia-lyase
CXP43_RS12465	COG0252	asparaginase activity
CXP43_RS12470	COG1396	sequence-specific DNA binding
CXP43_RS12475	COG1379	DNA repair
CXP43_RS12480	COG0494	nUDIX hydrolase
CXP43_RS12490	COG0667	Aldo Keto reductase
CXP43_RS12500	COG1073	alpha beta
CXP43_RS12510	COG4918	Iron-sulphur cluster biosynthesis
CXP43_RS12515	COG0456	acetyltransferase
CXP43_RS12515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CXP43_RS12520	COG2329	Antibiotic biosynthesis monooxygenase
CXP43_RS12525	COG0456	acetyltransferase
CXP43_RS12530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXP43_RS12545	COG0628	permease
CXP43_RS12555	COG0346	lactoylglutathione lyase activity
CXP43_RS12565	COG3048	D-serine ammonia-lyase activity
CXP43_RS12570	COG0300	oxidoreductase activity
CXP43_RS12575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXP43_RS12580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXP43_RS12585	COG1024	Enoyl-CoA hydratase
CXP43_RS12590	COG3425	synthase
CXP43_RS12595	COG2124	cytochrome p450
CXP43_RS12600	COG3321	synthase
CXP43_RS12600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS12600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS12600	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS12600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXP43_RS12605	COG3321	synthase
CXP43_RS12605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS12605	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS12605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXP43_RS12605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS12610	COG0300	oxidoreductase activity
CXP43_RS12610	COG3321	synthase
CXP43_RS12610	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS12610	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS12610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS12615	COG3321	synthase
CXP43_RS12615	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS12615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS12615	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS12615	COG0300	oxidoreductase activity
CXP43_RS12620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXP43_RS12620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS12620	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS12620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS12620	COG3321	synthase
CXP43_RS12625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS12625	COG3321	synthase
CXP43_RS12625	COG0300	oxidoreductase activity
CXP43_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS12625	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS12630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXP43_RS12630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS12630	COG3321	synthase
CXP43_RS12630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXP43_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS12635	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS12640	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS12655	COG2070	2-Nitropropane dioxygenase
CXP43_RS12655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXP43_RS12660	COG0250	Participates in transcription elongation, termination and antitermination
CXP43_RS12685	COG0596	Alpha beta hydrolase
CXP43_RS12700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CXP43_RS12705	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CXP43_RS12720	COG0706	membrane insertase activity
CXP43_RS12725	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXP43_RS12730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CXP43_RS12735	COG0346	lactoylglutathione lyase activity
CXP43_RS12740	COG1376	ErfK ybiS ycfS ynhG family protein
CXP43_RS12745	COG4129	membrane
CXP43_RS12750	COG1126	abc transporter atp-binding protein
CXP43_RS12755	COG0765	amino acid transport
CXP43_RS12760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXP43_RS12770	COG1597	lipid kinase activity
CXP43_RS12775	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXP43_RS12780	COG0022	dehydrogenase e1 component
CXP43_RS12785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CXP43_RS12790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXP43_RS12795	COG3426	butyrate kinase activity
CXP43_RS12800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXP43_RS12805	COG0280	phosphate acetyltransferase
CXP43_RS12810	COG3290	protein histidine kinase activity
CXP43_RS12810	COG3829	transcription factor binding
CXP43_RS12820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CXP43_RS12825	COG2079	MmgE PrpD family protein
CXP43_RS12830	COG0372	Belongs to the citrate synthase family
CXP43_RS12835	COG1960	acyl-CoA dehydrogenase activity
CXP43_RS12840	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXP43_RS12845	COG0183	Belongs to the thiolase family
CXP43_RS12850	COG0584	glycerophosphoryl diester phosphodiesterase
CXP43_RS12855	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS12875	COG1902	pentaerythritol trinitrate reductase activity
CXP43_RS12890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXP43_RS12895	COG0745	RESPONSE REGULATOR receiver
CXP43_RS12900	COG0750	zinc metalloprotease
CXP43_RS12905	COG0497	DNA recombination
CXP43_RS12915	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CXP43_RS12925	COG0142	geranyltranstransferase activity
CXP43_RS12935	COG1570	exodeoxyribonuclease VII activity
CXP43_RS12950	COG1302	Protein conserved in bacteria
CXP43_RS12955	COG0439	Biotin carboxylase
CXP43_RS12960	COG0511	ligase activity, forming carbon-carbon bonds
CXP43_RS13000	COG3854	ATPases associated with a variety of cellular activities
CXP43_RS13015	COG0006	proline dipeptidase activity
CXP43_RS13025	COG3872	metal-dependent enzyme
CXP43_RS13035	COG1752	Esterase of the alpha-beta hydrolase superfamily
CXP43_RS13050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXP43_RS13070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CXP43_RS13085	COG1396	sequence-specific DNA binding
CXP43_RS13095	COG0681	Belongs to the peptidase S26 family
CXP43_RS13120	COG4940	Competence protein ComGF
CXP43_RS13130	COG4970	Tfp pilus assembly protein FimT
CXP43_RS13135	COG4537	Required for transformation and DNA binding
CXP43_RS13140	COG1459	type II secretion system
CXP43_RS13145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXP43_RS13150	COG0598	Magnesium transport protein CorA
CXP43_RS13155	COG1253	flavin adenine dinucleotide binding
CXP43_RS13160	COG1366	Belongs to the anti-sigma-factor antagonist family
CXP43_RS13170	COG1393	Belongs to the ArsC family
CXP43_RS13180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXP43_RS13190	COG0011	TIGRFAM Protein of
CXP43_RS13200	COG2866	Carboxypeptidase
CXP43_RS13205	COG1940	carbohydrate kinase activity
CXP43_RS13210	COG4483	Protein conserved in bacteria
CXP43_RS13215	COG1757	Na H antiporter
CXP43_RS13225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CXP43_RS13240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXP43_RS13245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXP43_RS13250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXP43_RS13255	COG0581	inorganic phosphate transmembrane transporter activity
CXP43_RS13260	COG0573	inorganic phosphate transmembrane transporter activity
CXP43_RS13265	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXP43_RS13270	COG0768	penicillin binding
CXP43_RS13275	COG0477	Major facilitator Superfamily
CXP43_RS13280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXP43_RS13285	COG2839	Protein conserved in bacteria
CXP43_RS13290	COG5521	maltodextrose utilization protein MalA
CXP43_RS13295	COG1388	LysM domain
CXP43_RS13305	COG4709	membrane
CXP43_RS13310	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CXP43_RS13315	COG0735	belongs to the Fur family
CXP43_RS13320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXP43_RS13335	COG0513	Belongs to the DEAD box helicase family
CXP43_RS13350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CXP43_RS13355	COG2384	SAM-dependent methyltransferase
CXP43_RS13360	COG2010	Cytochrome c
CXP43_RS13365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXP43_RS13370	COG0358	DNA primase activity
CXP43_RS13385	COG0517	IMP dehydrogenase activity
CXP43_RS13390	COG0751	glycine-tRNA ligase activity
CXP43_RS13410	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CXP43_RS13415	COG0295	cytidine deaminase activity
CXP43_RS13420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CXP43_RS13430	COG1480	7TM receptor with intracellular HD hydrolase
CXP43_RS13435	COG1702	phosphate starvation-inducible protein PhoH
CXP43_RS13440	COG0561	phosphatase activity
CXP43_RS13455	COG4864	UPF0365 protein
CXP43_RS13460	COG1030	water channel activity
CXP43_RS13465	COG1610	YqeY-like protein
CXP43_RS13475	COG1283	sodium-dependent phosphate transmembrane transporter activity
CXP43_RS13480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CXP43_RS13485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CXP43_RS13515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXP43_RS13530	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS13545	COG1466	dna polymerase III delta subunit
CXP43_RS13555	COG2333	competence protein COMEC
CXP43_RS13555	COG0658	competence protein
CXP43_RS13560	COG2131	deaminase
CXP43_RS13565	COG1555	photosystem II stabilization
CXP43_RS13565	COG1596	polysaccharide export
CXP43_RS13570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXP43_RS13575	COG2226	methyltransferase
CXP43_RS13580	COG0799	negative regulation of ribosome biogenesis
CXP43_RS13585	COG1713	HD superfamily hydrolase involved in NAD metabolism
CXP43_RS13595	COG1534	Rna-binding protein
CXP43_RS13600	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CXP43_RS13605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CXP43_RS13610	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CXP43_RS13620	COG2755	lipolytic protein G-D-S-L family
CXP43_RS13630	COG0398	Pfam SNARE associated Golgi protein
CXP43_RS13675	COG2207	Transcriptional regulator
CXP43_RS13675	COG3708	Transcriptional regulator
CXP43_RS13680	COG0583	DNA-binding transcription factor activity
CXP43_RS13695	COG5002	protein histidine kinase activity
CXP43_RS13695	COG0642	Histidine kinase
CXP43_RS13700	COG0745	RESPONSE REGULATOR receiver
CXP43_RS13705	COG2311	Membrane
CXP43_RS13710	COG0454	-acetyltransferase
CXP43_RS13715	COG0563	adenylate kinase activity
CXP43_RS13725	COG2814	Major facilitator Superfamily
CXP43_RS13730	COG0456	acetyltransferase
CXP43_RS13735	COG2318	DinB family
CXP43_RS13745	COG0561	phosphatase activity
CXP43_RS13750	COG0561	phosphatase activity
CXP43_RS13760	COG1482	cell wall glycoprotein biosynthetic process
CXP43_RS13765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXP43_RS13765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXP43_RS13765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXP43_RS13770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXP43_RS13770	COG3711	transcriptional antiterminator
CXP43_RS13780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXP43_RS13785	COG0583	DNA-binding transcription factor activity
CXP43_RS13790	COG2814	Major facilitator Superfamily
CXP43_RS13795	COG2124	cytochrome p450
CXP43_RS13795	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CXP43_RS13800	COG1309	transcriptional regulator
CXP43_RS13805	COG2226	methyltransferase
CXP43_RS13820	COG2116	formate transmembrane transporter activity
CXP43_RS13825	COG5609	conserved protein (DUF2294)
CXP43_RS13830	COG3383	formate dehydrogenase (NAD+) activity
CXP43_RS13835	COG2427	Protein of unknown function (DUF1641)
CXP43_RS13845	COG0626	cystathionine gamma-synthase activity
CXP43_RS13850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXP43_RS13875	COG0768	penicillin binding
CXP43_RS13890	COG0826	peptidase U32
CXP43_RS13895	COG0826	peptidase U32
CXP43_RS13900	COG4122	O-methyltransferase activity
CXP43_RS13905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXP43_RS13920	COG4472	Bacterial protein of unknown function (DUF965)
CXP43_RS13930	COG0628	permease
CXP43_RS13935	COG1126	abc transporter atp-binding protein
CXP43_RS13940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXP43_RS13945	COG0765	amino acid transport
CXP43_RS13950	COG0765	amino acid transport
CXP43_RS13965	COG3881	PFAM PRC-barrel domain
CXP43_RS13970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CXP43_RS13975	COG0457	Tetratricopeptide repeat
CXP43_RS13985	COG1104	cysteine desulfurase activity
CXP43_RS13990	COG1959	2 iron, 2 sulfur cluster binding
CXP43_RS13995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXP43_RS14000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CXP43_RS14020	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS14020	COG4991	sh3 domain protein
CXP43_RS14020	COG3103	Sh3 type 3 domain protein
CXP43_RS14030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXP43_RS14040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXP43_RS14040	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CXP43_RS14045	COG5416	Lipopolysaccharide assembly protein A domain
CXP43_RS14050	COG0490	domain, Protein
CXP43_RS14055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXP43_RS14055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXP43_RS14065	COG2244	polysaccharide biosynthetic process
CXP43_RS14070	COG2323	membrane
CXP43_RS14080	COG1862	Preprotein translocase
CXP43_RS14125	COG1388	LysM domain
CXP43_RS14135	COG0157	Belongs to the NadC ModD family
CXP43_RS14140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXP43_RS14145	COG1104	cysteine desulfurase activity
CXP43_RS14150	COG1827	regulation of RNA biosynthetic process
CXP43_RS14155	COG0077	Prephenate dehydratase
CXP43_RS14170	COG3290	protein histidine kinase activity
CXP43_RS14175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CXP43_RS14180	COG2868	ribosomal protein
CXP43_RS14190	COG1994	Peptidase M50
CXP43_RS14195	COG0739	heme binding
CXP43_RS14200	COG2894	cell division
CXP43_RS14210	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CXP43_RS14220	COG1077	Cell shape determining protein MreB Mrl
CXP43_RS14240	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CXP43_RS14245	COG0285	dihydrofolate synthase activity
CXP43_RS14250	COG0525	valine-tRNA ligase activity
CXP43_RS14260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXP43_RS14265	COG1388	LysM domain
CXP43_RS14275	COG0113	porphobilinogen synthase activity
CXP43_RS14280	COG1587	Uroporphyrinogen-III synthase
CXP43_RS14290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXP43_RS14310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CXP43_RS14315	COG1067	ATP-dependent peptidase activity
CXP43_RS14315	COG0470	DNA polymerase III
CXP43_RS14330	COG0457	Tetratricopeptide repeat
CXP43_RS14330	COG1477	protein flavinylation
CXP43_RS14345	COG0473	3-isopropylmalate dehydrogenase activity
CXP43_RS14360	COG0440	acetolactate synthase activity
CXP43_RS14365	COG0028	Belongs to the TPP enzyme family
CXP43_RS14395	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CXP43_RS14420	COG0622	Phosphoesterase
CXP43_RS14425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CXP43_RS14435	COG5401	PFAM Sporulation and spore germination
CXP43_RS14445	COG1846	Transcriptional regulator
CXP43_RS14450	COG2197	response regulator
CXP43_RS14455	COG0824	Thioesterase
CXP43_RS14460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXP43_RS14465	COG1053	succinate dehydrogenase
CXP43_RS14470	COG2009	succinate dehydrogenase
CXP43_RS14475	COG1719	4-vinyl reductase, 4VR
CXP43_RS14480	COG0527	aspartate kinase activity
CXP43_RS14495	COG3118	belongs to the thioredoxin family
CXP43_RS14500	COG3534	alpha-L-arabinofuranosidase
CXP43_RS14505	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CXP43_RS14510	COG2086	electron transfer activity
CXP43_RS14515	COG1024	Enoyl-CoA hydratase
CXP43_RS14520	COG1309	transcriptional regulator
CXP43_RS14525	COG0318	PFAM AMP-dependent synthetase and ligase
CXP43_RS14535	COG3766	membrane
CXP43_RS14545	COG1796	DNA polymerase
CXP43_RS14545	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CXP43_RS14550	COG1286	toxin biosynthetic process
CXP43_RS14565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXP43_RS14565	COG0072	phenylalanine-tRNA ligase activity
CXP43_RS14570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CXP43_RS14575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXP43_RS14585	COG3835	regulator
CXP43_RS14590	COG0277	FAD linked oxidase domain protein
CXP43_RS14595	COG0247	lactate metabolic process
CXP43_RS14600	COG1966	Carbon starvation protein
CXP43_RS14605	COG3534	alpha-L-arabinofuranosidase
CXP43_RS14610	COG0395	ABC-type sugar transport system, permease component
CXP43_RS14615	COG1175	transmembrane transport
CXP43_RS14620	COG1653	transport
CXP43_RS14630	COG0647	UMP catabolic process
CXP43_RS14635	COG0235	Class ii aldolase
CXP43_RS14640	COG1069	ribulokinase activity
CXP43_RS14645	COG2160	L-arabinose isomerase activity
CXP43_RS14650	COG3507	Belongs to the glycosyl hydrolase 43 family
CXP43_RS14655	COG1363	Peptidase, m42
CXP43_RS14665	COG3326	Membrane
CXP43_RS14680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CXP43_RS14685	COG1346	cytolysis
CXP43_RS14690	COG1380	Effector of murein hydrolase LrgA
CXP43_RS14695	COG3279	Response regulator of the LytR AlgR family
CXP43_RS14700	COG3275	phosphorelay sensor kinase activity
CXP43_RS14710	COG1011	Hydrolase
CXP43_RS14725	COG0398	Pfam SNARE associated Golgi protein
CXP43_RS14730	COG1484	DNA-dependent DNA replication
CXP43_RS14735	COG3611	Membrane attachment protein
CXP43_RS14750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXP43_RS14755	COG1733	regulation of RNA biosynthetic process
CXP43_RS14760	COG2814	Major facilitator Superfamily
CXP43_RS14765	COG0656	L-ascorbic acid biosynthetic process
CXP43_RS14770	COG0237	dephospho-CoA kinase activity
CXP43_RS14775	COG1971	Probably functions as a manganese efflux pump
CXP43_RS14780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CXP43_RS14785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXP43_RS14785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXP43_RS14790	COG5002	protein histidine kinase activity
CXP43_RS14795	COG0745	RESPONSE REGULATOR receiver
CXP43_RS14805	COG0538	isocitrate dehydrogenase activity
CXP43_RS14810	COG0372	Belongs to the citrate synthase family
CXP43_RS14815	COG0457	Tetratricopeptide repeat
CXP43_RS14845	COG0628	permease
CXP43_RS14850	COG3030	protein affecting phage T7 exclusion by the F plasmid
CXP43_RS14855	COG0469	pyruvate kinase activity
CXP43_RS14875	COG0281	malic enzyme
CXP43_RS14880	COG0587	DNA-directed DNA polymerase activity
CXP43_RS14900	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CXP43_RS14910	COG4109	DRTGG domain
CXP43_RS14920	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS14935	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXP43_RS14945	COG0827	DNA restriction-modification system
CXP43_RS14950	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXP43_RS14955	COG3874	Sporulation protein YtfJ
CXP43_RS14965	COG1714	RDD family
CXP43_RS14970	COG0616	signal peptide processing
CXP43_RS14975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CXP43_RS14980	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CXP43_RS14985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXP43_RS15000	COG1104	cysteine desulfurase activity
CXP43_RS15005	COG1114	Component of the transport system for branched-chain amino acids
CXP43_RS15015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CXP43_RS15020	COG1309	transcriptional regulator
CXP43_RS15025	COG1956	GAF domain-containing protein
CXP43_RS15030	COG2203	Gaf domain
CXP43_RS15030	COG2199	diguanylate cyclase activity
CXP43_RS15045	COG1012	belongs to the aldehyde dehydrogenase family
CXP43_RS15050	COG4282	regulation of fungal-type cell wall biogenesis
CXP43_RS15100	COG1017	nitric oxide dioxygenase activity
CXP43_RS15100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXP43_RS15110	COG0693	protein deglycase activity
CXP43_RS15125	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXP43_RS15130	COG1378	Sugar-specific transcriptional regulator TrmB
CXP43_RS15155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXP43_RS15160	COG0454	-acetyltransferase
CXP43_RS15165	COG0517	IMP dehydrogenase activity
CXP43_RS15170	COG0123	including yeast histone deacetylase and acetoin utilization protein
CXP43_RS15175	COG1360	Flagellar Motor Protein
CXP43_RS15180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXP43_RS15185	COG1609	Transcriptional regulator
CXP43_RS15190	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CXP43_RS15190	COG1605	Chorismate mutase
CXP43_RS15195	COG3118	belongs to the thioredoxin family
CXP43_RS15200	COG4980	gas vesicle protein
CXP43_RS15205	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CXP43_RS15215	COG1674	ftsk spoiiie
CXP43_RS15220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXP43_RS15230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXP43_RS15250	COG1363	Peptidase, m42
CXP43_RS15255	COG5584	Small secreted protein
CXP43_RS15260	COG0281	malic enzyme
CXP43_RS15265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXP43_RS15280	COG0510	thiamine kinase activity
CXP43_RS15285	COG1597	lipid kinase activity
CXP43_RS15295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CXP43_RS15300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXP43_RS15305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXP43_RS15310	COG2252	PERMEase
CXP43_RS15315	COG4473	ABC transporter
CXP43_RS15320	COG1131	(ABC) transporter
CXP43_RS15325	COG1349	DNA-binding transcription factor activity
CXP43_RS15330	COG1187	pseudouridine synthase activity
CXP43_RS15335	COG2244	polysaccharide biosynthetic process
CXP43_RS15340	COG2081	HI0933 family
CXP43_RS15345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXP43_RS15355	COG1609	Transcriptional regulator
CXP43_RS15360	COG1653	transport
CXP43_RS15365	COG1175	transmembrane transport
CXP43_RS15370	COG0395	ABC-type sugar transport system, permease component
CXP43_RS15375	COG1486	melibiose metabolic process
CXP43_RS15385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXP43_RS15400	COG2202	Pas domain
CXP43_RS15400	COG1366	Belongs to the anti-sigma-factor antagonist family
CXP43_RS15405	COG2814	Major facilitator Superfamily
CXP43_RS15410	COG5522	Integral membrane protein (intg_mem_TP0381)
CXP43_RS15415	COG0577	efflux transmembrane transporter activity
CXP43_RS15420	COG1136	(ABC) transporter
CXP43_RS15425	COG2205	protein histidine kinase activity
CXP43_RS15430	COG0745	RESPONSE REGULATOR receiver
CXP43_RS15435	COG0577	efflux transmembrane transporter activity
CXP43_RS15440	COG1136	(ABC) transporter
CXP43_RS15460	COG1131	(ABC) transporter
CXP43_RS15465	COG1725	Transcriptional regulator
CXP43_RS15475	COG1242	4 iron, 4 sulfur cluster binding
CXP43_RS15480	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CXP43_RS15490	COG0584	glycerophosphoryl diester phosphodiesterase
CXP43_RS15500	COG2267	carboxylic ester hydrolase activity
CXP43_RS15505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXP43_RS15510	COG1113	amino acid transport
CXP43_RS15515	COG0367	asparagine synthase
CXP43_RS15535	COG1506	peptidase
CXP43_RS15540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CXP43_RS15545	COG1116	anion transmembrane transporter activity
CXP43_RS15550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXP43_RS15555	COG0494	nUDIX hydrolase
CXP43_RS15560	COG4824	toxin secretion phage lysis holin
CXP43_RS15565	COG0783	Belongs to the Dps family
CXP43_RS15590	COG0288	reversible hydration of carbon dioxide
CXP43_RS15600	COG1271	oxidase subunit
CXP43_RS15605	COG1294	oxidase, subunit
CXP43_RS15615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXP43_RS15620	COG1321	iron dependent repressor
CXP43_RS15620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXP43_RS15625	COG1121	(ABC) transporter
CXP43_RS15630	COG0803	Belongs to the bacterial solute-binding protein 9 family
CXP43_RS15635	COG4948	Mandelate Racemase Muconate Lactonizing
CXP43_RS15645	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CXP43_RS15650	COG0596	Alpha beta hydrolase
CXP43_RS15660	COG1169	isochorismate synthase
CXP43_RS15665	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXP43_RS15670	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CXP43_RS15795	COG3859	Proton-coupled thiamine transporter YuaJ
CXP43_RS15800	COG2268	Band 7 protein
CXP43_RS15805	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXP43_RS15810	COG2318	DinB family
CXP43_RS15820	COG1454	alcohol dehydrogenase
CXP43_RS15825	COG1012	belongs to the aldehyde dehydrogenase family
CXP43_RS15830	COG1510	regulation of RNA biosynthetic process
CXP43_RS15840	COG0569	domain protein
CXP43_RS15845	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXP43_RS15850	COG1017	nitric oxide dioxygenase activity
CXP43_RS15850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXP43_RS15890	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS15890	COG3409	Peptidoglycan-binding domain 1 protein
CXP43_RS15915	COG5434	Belongs to the glycosyl hydrolase 28 family
CXP43_RS15920	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXP43_RS16000	COG0582	viral genome integration into host DNA
CXP43_RS16010	COG1216	Glycosyl transferase, family 2
CXP43_RS16020	COG4195	phage-related replication protein
CXP43_RS16025	COG3420	alginic acid biosynthetic process
CXP43_RS16025	COG5434	Belongs to the glycosyl hydrolase 28 family
CXP43_RS16055	COG1793	dna ligase
CXP43_RS16070	COG1595	DNA-templated transcription, initiation
CXP43_RS16095	COG1388	LysM domain
CXP43_RS16095	COG3584	3D domain protein
CXP43_RS16100	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CXP43_RS16110	COG0756	dUTP diphosphatase activity
CXP43_RS16115	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXP43_RS16125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXP43_RS16135	COG1780	Probably involved in ribonucleotide reductase function
CXP43_RS16175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CXP43_RS16190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXP43_RS16190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXP43_RS16225	COG3655	Transcriptional regulator
CXP43_RS16250	COG1484	DNA-dependent DNA replication
CXP43_RS16295	COG4974	Belongs to the 'phage' integrase family
CXP43_RS16310	COG0628	permease
CXP43_RS16315	COG0673	inositol 2-dehydrogenase activity
CXP43_RS16320	COG0693	protein deglycase activity
CXP43_RS16325	COG0840	transmembrane signaling receptor activity
CXP43_RS16330	COG0840	transmembrane signaling receptor activity
CXP43_RS16335	COG0840	transmembrane signaling receptor activity
CXP43_RS16340	COG0840	transmembrane signaling receptor activity
CXP43_RS16355	COG2070	2-Nitropropane dioxygenase
CXP43_RS16360	COG0432	Pfam Uncharacterised protein family UPF0047
CXP43_RS16365	COG0366	Alpha amylase catalytic
CXP43_RS16370	COG1253	flavin adenine dinucleotide binding
CXP43_RS16375	COG2738	Putative neutral zinc metallopeptidase
CXP43_RS16390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXP43_RS16420	COG1335	isochorismatase
CXP43_RS16425	COG1979	alcohol dehydrogenase
CXP43_RS16430	COG1979	alcohol dehydrogenase
CXP43_RS16435	COG2155	Conserved Protein
CXP43_RS16440	COG1098	S1 RNA binding domain
CXP43_RS16445	COG0436	Aminotransferase
CXP43_RS16450	COG1522	sequence-specific DNA binding
CXP43_RS16455	COG2267	carboxylic ester hydrolase activity
CXP43_RS16465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXP43_RS16470	COG2205	protein histidine kinase activity
CXP43_RS16480	COG5018	Exonuclease
CXP43_RS16485	COG2814	Major facilitator Superfamily
CXP43_RS16490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXP43_RS16495	COG3011	Protein conserved in bacteria
CXP43_RS16505	COG3290	protein histidine kinase activity
CXP43_RS16510	COG4565	transcriptional regulatory protein
CXP43_RS16515	COG1744	ABC transporter substrate-binding protein PnrA-like
CXP43_RS16520	COG3845	ABC transporter
CXP43_RS16525	COG4603	Belongs to the binding-protein-dependent transport system permease family
CXP43_RS16530	COG1079	Belongs to the binding-protein-dependent transport system permease family
CXP43_RS16540	COG2111	Na H antiporter
CXP43_RS16540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXP43_RS16545	COG2111	Na H antiporter
CXP43_RS16550	COG1006	Multisubunit Na H antiporter MnhC subunit
CXP43_RS16555	COG0651	ATP synthesis coupled electron transport
CXP43_RS16560	COG1863	multisubunit Na H antiporter MnhE subunit
CXP43_RS16565	COG2212	antiporter activity
CXP43_RS16570	COG1320	monovalent cation:proton antiporter activity
CXP43_RS16575	COG2050	protein possibly involved in aromatic compounds catabolism
CXP43_RS16580	COG2197	response regulator
CXP43_RS16585	COG4585	Histidine kinase
CXP43_RS16595	COG0142	geranyltranstransferase activity
CXP43_RS16615	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CXP43_RS16620	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CXP43_RS16625	COG1335	isochorismatase
CXP43_RS16630	COG5506	Protein of unknown function (DUF1694)
CXP43_RS16645	COG0628	permease
CXP43_RS16655	COG1418	mRNA catabolic process
CXP43_RS16660	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS16670	COG1511	domain protein
CXP43_RS16675	COG1674	ftsk spoiiie
CXP43_RS16675	COG0433	COG0433 Predicted ATPase
CXP43_RS16680	COG4499	WXG100 protein secretion system (Wss), protein YukC
CXP43_RS16685	COG5417	Belongs to the EsaB family
CXP43_RS16690	COG4842	Belongs to the WXG100 family
CXP43_RS16695	COG2508	Transcriptional regulator
CXP43_RS16695	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CXP43_RS16700	COG0686	Belongs to the AlaDH PNT family
CXP43_RS16705	COG5634	Uncharacterized conserved protein (DUF2278)
CXP43_RS16710	COG3251	PFAM MbtH domain protein
CXP43_RS16715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXP43_RS16720	COG3433	isochorismatase activity
CXP43_RS16720	COG1535	isochorismatase
CXP43_RS16725	COG1021	2,3-dihydroxybenzoate-AMP ligase
CXP43_RS16730	COG1169	isochorismate synthase
CXP43_RS16735	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS16740	COG2819	hydrolase of the alpha beta superfamily
CXP43_RS16745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CXP43_RS16750	COG1268	BioY protein
CXP43_RS16755	COG2056	Na+-H+ antiporter family
CXP43_RS16765	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CXP43_RS16770	COG3584	3D domain protein
CXP43_RS16785	COG1252	NADH dehydrogenase
CXP43_RS16815	COG1131	(ABC) transporter
CXP43_RS16835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXP43_RS16840	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CXP43_RS16860	COG0316	Belongs to the HesB IscA family
CXP43_RS16870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXP43_RS16880	COG1252	NADH dehydrogenase
CXP43_RS16885	COG4837	Protein of unknown function (DUF1462)
CXP43_RS16890	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CXP43_RS16895	COG1506	peptidase
CXP43_RS16895	COG4946	Tricorn protease homolog
CXP43_RS16895	COG0823	Involved in the tonB-independent uptake of proteins
CXP43_RS16905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CXP43_RS16910	COG0460	homoserine dehydrogenase
CXP43_RS16915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXP43_RS16920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXP43_RS16925	COG0647	UMP catabolic process
CXP43_RS16930	COG2445	Protein of unknown function DUF86
CXP43_RS16935	COG4470	Protein conserved in bacteria
CXP43_RS16950	COG0739	heme binding
CXP43_RS16960	COG0737	Belongs to the 5'-nucleotidase family
CXP43_RS16965	COG0730	response to heat
CXP43_RS16970	COG1801	Protein of unknown function DUF72
CXP43_RS16985	COG2508	Transcriptional regulator
CXP43_RS16990	COG0457	Tetratricopeptide repeat
CXP43_RS17005	COG2814	Major facilitator Superfamily
CXP43_RS17010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CXP43_RS17015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXP43_RS17020	COG2356	endonuclease I
CXP43_RS17025	COG3842	ATPase activity
CXP43_RS17030	COG2188	Transcriptional regulator
CXP43_RS17035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXP43_RS17040	COG0395	ABC-type sugar transport system, permease component
CXP43_RS17045	COG1175	transmembrane transport
CXP43_RS17050	COG1653	transport
CXP43_RS17055	COG2222	sugar isomerase
CXP43_RS17060	COG0789	Transcriptional regulator
CXP43_RS17085	COG0322	excinuclease ABC activity
CXP43_RS17090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXP43_RS17115	COG3409	Peptidoglycan-binding domain 1 protein
CXP43_RS17120	COG0719	Fe-S assembly protein
CXP43_RS17125	COG0822	iron-sulfur transferase activity
CXP43_RS17130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXP43_RS17135	COG0719	Fe-S assembly protein
CXP43_RS17140	COG0396	ATPase activity
CXP43_RS17150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXP43_RS17155	COG1464	Belongs to the NlpA lipoprotein family
CXP43_RS17160	COG2011	ABC-type metal ion transport system permease component
CXP43_RS17165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXP43_RS17175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXP43_RS17180	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CXP43_RS17195	COG1393	Belongs to the ArsC family
CXP43_RS17200	COG1960	acyl-CoA dehydrogenase activity
CXP43_RS17205	COG0183	Belongs to the thiolase family
CXP43_RS17210	COG1024	Enoyl-CoA hydratase
CXP43_RS17210	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXP43_RS17230	COG5577	PFAM Coat F domain
CXP43_RS17235	COG1846	Transcriptional regulator
CXP43_RS17240	COG0477	Major facilitator Superfamily
CXP43_RS17245	COG0583	DNA-binding transcription factor activity
CXP43_RS17265	COG1120	ATPase activity
CXP43_RS17280	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS17285	COG0783	Belongs to the Dps family
CXP43_RS17290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXP43_RS17295	COG0745	RESPONSE REGULATOR receiver
CXP43_RS17300	COG2770	Histidine kinase
CXP43_RS17300	COG2205	protein histidine kinase activity
CXP43_RS17310	COG1309	transcriptional regulator
CXP43_RS17315	COG0114	fumarate hydratase activity
CXP43_RS17325	COG0697	spore germination
CXP43_RS17330	COG0814	amino acid
CXP43_RS17340	COG2197	response regulator
CXP43_RS17345	COG4585	Histidine kinase
CXP43_RS17350	COG4758	membrane
CXP43_RS17355	COG3595	metallopeptidase activity
CXP43_RS17360	COG1842	Phage shock protein A
CXP43_RS17365	COG4758	membrane
CXP43_RS17370	COG2814	Major facilitator Superfamily
CXP43_RS17375	COG2096	Adenosyltransferase
CXP43_RS17380	COG1120	ATPase activity
CXP43_RS17385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXP43_RS17390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXP43_RS17395	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS17400	COG3386	PFAM SMP-30 Gluconolaconase
CXP43_RS17405	COG2205	protein histidine kinase activity
CXP43_RS17410	COG0745	RESPONSE REGULATOR receiver
CXP43_RS17420	COG1191	sigma factor activity
CXP43_RS17430	COG2140	Oxalate decarboxylase
CXP43_RS17440	COG1120	ATPase activity
CXP43_RS17445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXP43_RS17450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXP43_RS17455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXP43_RS17460	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CXP43_RS17465	COG0531	amino acid
CXP43_RS17480	COG1988	membrane-bound metal-dependent
CXP43_RS17485	COG1368	sulfuric ester hydrolase activity
CXP43_RS17490	COG1910	domain protein
CXP43_RS17495	COG0725	ABC transporter, periplasmic molybdate-binding protein
CXP43_RS17500	COG4149	molybdate abc transporter
CXP43_RS17505	COG2197	response regulator
CXP43_RS17510	COG3850	Histidine kinase
CXP43_RS17515	COG1131	(ABC) transporter
CXP43_RS17525	COG0842	Transport permease protein
CXP43_RS17530	COG0656	L-ascorbic acid biosynthetic process
CXP43_RS17555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CXP43_RS17560	COG3973	AAA domain
CXP43_RS17565	COG2860	membrane
CXP43_RS17575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CXP43_RS17580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXP43_RS17585	COG2217	Heavy metal translocating P-type atpase
CXP43_RS17590	COG2217	Heavy metal translocating P-type atpase
CXP43_RS17595	COG2608	mercury ion transmembrane transporter activity
CXP43_RS17600	COG1937	Protein conserved in bacteria
CXP43_RS17605	COG0673	inositol 2-dehydrogenase activity
CXP43_RS17615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXP43_RS17620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXP43_RS17625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXP43_RS17630	COG1126	abc transporter atp-binding protein
CXP43_RS17635	COG0765	amino acid transport
CXP43_RS17640	COG0765	amino acid transport
CXP43_RS17645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXP43_RS17650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXP43_RS17655	COG0454	-acetyltransferase
CXP43_RS17660	COG0583	DNA-binding transcription factor activity
CXP43_RS17665	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS17670	COG2732	(Barnase) inhibitor
CXP43_RS17680	COG2732	(Barnase) inhibitor
CXP43_RS17695	COG0557	exoribonuclease II activity
CXP43_RS17700	COG1647	Serine aminopeptidase, S33
CXP43_RS17705	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXP43_RS17710	COG1476	TRANSCRIPTIONal
CXP43_RS17715	COG1396	sequence-specific DNA binding
CXP43_RS17720	COG1396	sequence-specific DNA binding
CXP43_RS17725	COG1733	regulation of RNA biosynthetic process
CXP43_RS17750	COG1131	(ABC) transporter
CXP43_RS17755	COG1174	glycine betaine transport
CXP43_RS17760	COG1732	Glycine betaine
CXP43_RS17765	COG1174	glycine betaine transport
CXP43_RS17770	COG1125	glycine betaine transport
CXP43_RS17770	COG0517	IMP dehydrogenase activity
CXP43_RS17775	COG1510	regulation of RNA biosynthetic process
CXP43_RS17780	COG1174	glycine betaine transport
CXP43_RS17785	COG1732	Glycine betaine
CXP43_RS17790	COG1174	glycine betaine transport
CXP43_RS17795	COG1125	glycine betaine transport
CXP43_RS17795	COG0517	IMP dehydrogenase activity
CXP43_RS17800	COG1510	regulation of RNA biosynthetic process
CXP43_RS17805	COG2095	MarC family integral membrane protein
CXP43_RS17815	COG3064	Membrane
CXP43_RS17820	COG4640	response to antibiotic
CXP43_RS17825	COG0456	acetyltransferase
CXP43_RS17845	COG0126	phosphoglycerate kinase activity
CXP43_RS17855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXP43_RS17860	COG2390	Transcriptional regulator
CXP43_RS17865	COG2814	Major facilitator Superfamily
CXP43_RS17870	COG1609	Transcriptional regulator
CXP43_RS17875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXP43_RS17880	COG0583	DNA-binding transcription factor activity
CXP43_RS17885	COG0697	spore germination
CXP43_RS17890	COG1113	amino acid transport
CXP43_RS17895	COG1737	Transcriptional regulator
CXP43_RS17900	COG1070	Carbohydrate kinase
CXP43_RS17935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXP43_RS17940	COG2186	Transcriptional regulator
CXP43_RS17945	COG1620	l-lactate permease
CXP43_RS17950	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CXP43_RS17960	COG5039	Polysaccharide pyruvyl transferase
CXP43_RS17965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXP43_RS17970	COG0110	maltose O-acetyltransferase activity
CXP43_RS17975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CXP43_RS17980	COG2244	polysaccharide biosynthetic process
CXP43_RS17985	COG1216	Glycosyl transferase, family 2
CXP43_RS17990	COG5039	Polysaccharide pyruvyl transferase
CXP43_RS17995	COG1216	Glycosyl transferase, family 2
CXP43_RS18005	COG0438	transferase activity, transferring glycosyl groups
CXP43_RS18010	COG1215	transferase activity, transferring glycosyl groups
CXP43_RS18015	COG0438	transferase activity, transferring glycosyl groups
CXP43_RS18020	COG1086	Polysaccharide biosynthesis protein
CXP43_RS18025	COG0489	protein tyrosine kinase activity
CXP43_RS18030	COG3944	biosynthesis protein
CXP43_RS18035	COG1396	sequence-specific DNA binding
CXP43_RS18040	COG2272	Belongs to the type-B carboxylesterase lipase family
CXP43_RS18050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXP43_RS18055	COG2364	Membrane
CXP43_RS18060	COG0456	acetyltransferase
CXP43_RS18065	COG3479	Phenolic acid decarboxylase
CXP43_RS18120	COG2223	nitrite transmembrane transporter activity
CXP43_RS18125	COG1609	Transcriptional regulator
CXP43_RS18135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXP43_RS18140	COG0366	Alpha amylase catalytic
CXP43_RS18145	COG1554	hydrolase, family 65, central catalytic
CXP43_RS18150	COG5521	maltodextrose utilization protein MalA
CXP43_RS18155	COG3833	ABC-type maltose transport systems, permease component
CXP43_RS18160	COG1175	transmembrane transport
CXP43_RS18165	COG2182	Extracellular solute-binding protein
CXP43_RS18170	COG0366	Alpha amylase catalytic
CXP43_RS18175	COG1609	Transcriptional regulator
CXP43_RS18180	COG1611	Belongs to the LOG family
CXP43_RS18185	COG1694	Mazg nucleotide pyrophosphohydrolase
CXP43_RS18190	COG0659	secondary active sulfate transmembrane transporter activity
CXP43_RS18195	COG0288	reversible hydration of carbon dioxide
CXP43_RS18205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXP43_RS18210	COG4290	ribonuclease
CXP43_RS18215	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CXP43_RS18220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXP43_RS18230	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CXP43_RS18240	COG1051	belongs to the nudix hydrolase family
CXP43_RS18245	COG0492	ferredoxin-NADP+ reductase activity
CXP43_RS18250	COG3883	PFAM NLP P60 protein
CXP43_RS18250	COG0791	NLP P60 protein
CXP43_RS18255	COG0457	Tetratricopeptide repeat
CXP43_RS18260	COG5002	protein histidine kinase activity
CXP43_RS18265	COG0745	RESPONSE REGULATOR receiver
CXP43_RS18275	COG1132	(ABC) transporter
CXP43_RS18280	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CXP43_RS18280	COG0140	phosphoribosyl-ATP diphosphatase activity
CXP43_RS18305	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CXP43_RS18320	COG4990	cell redox homeostasis
CXP43_RS18325	COG0110	maltose O-acetyltransferase activity
CXP43_RS18345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXP43_RS18355	COG2188	Transcriptional regulator
CXP43_RS18360	COG1309	transcriptional regulator
CXP43_RS18365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXP43_RS18370	COG1950	PFAM Membrane protein of
CXP43_RS18375	COG1983	PspC domain protein
CXP43_RS18380	COG3595	metallopeptidase activity
CXP43_RS18395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CXP43_RS18405	COG4897	Protein conserved in bacteria
CXP43_RS18410	COG3848	Pyruvate phosphate dikinase
CXP43_RS18410	COG0574	Belongs to the PEP-utilizing enzyme family
CXP43_RS18415	COG1309	transcriptional regulator
CXP43_RS18420	COG2814	Major facilitator Superfamily
CXP43_RS18455	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS18470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXP43_RS18480	COG3409	Peptidoglycan-binding domain 1 protein
CXP43_RS18480	COG0793	Belongs to the peptidase S41A family
CXP43_RS18485	COG3420	alginic acid biosynthetic process
CXP43_RS18490	COG2177	Part of the ABC transporter FtsEX involved in
CXP43_RS18495	COG2884	Cell division ATP-binding protein ftsE
CXP43_RS18500	COG2010	Cytochrome c
CXP43_RS18505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXP43_RS18520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXP43_RS18535	COG1516	flagellar protein fliS
CXP43_RS18540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CXP43_RS18545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXP43_RS18565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXP43_RS18570	COG1256	bacterial-type flagellum assembly
CXP43_RS18570	COG4786	Flagellar basal body rod
CXP43_RS18575	COG3418	PFAM FlgN family protein
CXP43_RS18580	COG2747	anti-sigma28 factor FlgM
CXP43_RS18590	COG1040	competence protein
CXP43_RS18600	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CXP43_RS18605	COG1307	EDD domain protein, DegV family
CXP43_RS18610	COG2197	response regulator
CXP43_RS18615	COG4585	Histidine kinase
CXP43_RS18620	COG1739	Uncharacterized protein family UPF0029
CXP43_RS18625	COG1316	TRANSCRIPTIONal
CXP43_RS18630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXP43_RS18635	COG0438	transferase activity, transferring glycosyl groups
CXP43_RS18640	COG1215	transferase activity, transferring glycosyl groups
CXP43_RS18645	COG3206	protein involved in exopolysaccharide biosynthesis
CXP43_RS18650	COG3307	-O-antigen
CXP43_RS18655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CXP43_RS18660	COG0438	transferase activity, transferring glycosyl groups
CXP43_RS18660	COG0297	glycogen (starch) synthase activity
CXP43_RS18665	COG2244	polysaccharide biosynthetic process
CXP43_RS18675	COG2247	cell wall binding repeat
CXP43_RS18675	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXP43_RS18680	COG2247	cell wall binding repeat
CXP43_RS18680	COG2385	sporulation resulting in formation of a cellular spore
CXP43_RS18690	COG1316	TRANSCRIPTIONal
CXP43_RS18695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CXP43_RS18700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXP43_RS18705	COG1134	teichoic acid transport
CXP43_RS18710	COG1682	transport, permease protein
CXP43_RS18715	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CXP43_RS18725	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CXP43_RS18730	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CXP43_RS18735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CXP43_RS18740	COG4193	domain, Protein
CXP43_RS18745	COG1482	cell wall glycoprotein biosynthetic process
CXP43_RS18750	COG0697	spore germination
CXP43_RS18755	COG0814	amino acid
CXP43_RS18765	COG1215	transferase activity, transferring glycosyl groups
CXP43_RS18770	COG2814	Major facilitator Superfamily
CXP43_RS18775	COG1316	TRANSCRIPTIONal
CXP43_RS18780	COG0561	phosphatase activity
CXP43_RS18785	COG2433	Pfam Transposase IS66
CXP43_RS18790	COG0791	NLP P60 protein
CXP43_RS18800	COG2843	Capsule synthesis protein
CXP43_RS18810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CXP43_RS18820	COG0697	spore germination
CXP43_RS18825	COG0814	amino acid
CXP43_RS18835	COG1609	Transcriptional regulator
CXP43_RS18840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXP43_RS18850	COG1129	ABC transporter
CXP43_RS18855	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXP43_RS18860	COG1879	ABC-type sugar transport system periplasmic component
CXP43_RS18865	COG3103	Sh3 type 3 domain protein
CXP43_RS18870	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXP43_RS18875	COG3527	Alpha-acetolactate decarboxylase
CXP43_RS18880	COG0028	Belongs to the TPP enzyme family
CXP43_RS18885	COG0583	DNA-binding transcription factor activity
CXP43_RS18890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXP43_RS18905	COG5337	Spore coat protein CotH
CXP43_RS18915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXP43_RS18925	COG0405	Gamma-glutamyltransferase
CXP43_RS18930	COG1522	sequence-specific DNA binding
CXP43_RS18935	COG2059	Chromate
CXP43_RS18940	COG2059	Chromate
CXP43_RS18950	COG0655	NAD(P)H dehydrogenase (quinone) activity
CXP43_RS18955	COG0583	DNA-binding transcription factor activity
CXP43_RS18990	COG5444	nuclease activity
CXP43_RS19005	COG3878	Protein conserved in bacteria
CXP43_RS19010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CXP43_RS19015	COG4464	protein tyrosine phosphatase activity
CXP43_RS19020	COG0489	protein tyrosine kinase activity
CXP43_RS19025	COG3944	biosynthesis protein
CXP43_RS19040	COG4715	Zinc finger, swim domain protein
CXP43_RS19045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CXP43_RS19050	COG0561	phosphatase activity
CXP43_RS19055	COG1349	DNA-binding transcription factor activity
CXP43_RS19060	COG0629	single-stranded DNA binding
CXP43_RS19085	COG0457	Tetratricopeptide repeat
CXP43_RS19090	COG4786	Flagellar basal body rod
CXP43_RS19095	COG4786	Flagellar basal body rod
CXP43_RS19100	COG1077	Cell shape determining protein MreB Mrl
CXP43_RS19105	COG1609	Transcriptional regulator
CXP43_RS19110	COG1846	Transcriptional regulator
CXP43_RS19115	COG2814	Major facilitator Superfamily
CXP43_RS19120	COG1953	Uracil, thiamine, allantoin
CXP43_RS19125	COG0477	Major facilitator Superfamily
CXP43_RS19130	COG1335	isochorismatase
CXP43_RS19135	COG0004	ammonium transporteR
CXP43_RS19140	COG0347	Belongs to the P(II) protein family
CXP43_RS19145	COG0772	Belongs to the SEDS family
CXP43_RS19150	COG0671	phosphoesterase, PA-phosphatase related
CXP43_RS19160	COG0739	heme binding
CXP43_RS19165	COG1247	-acetyltransferase
CXP43_RS19180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXP43_RS19190	COG0726	polysaccharide deacetylase
CXP43_RS19200	COG1959	2 iron, 2 sulfur cluster binding
CXP43_RS19215	COG0831	urea catabolic process
CXP43_RS19225	COG1994	Peptidase M50
CXP43_RS19230	COG0457	Tetratricopeptide repeat
CXP43_RS19240	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CXP43_RS19245	COG2304	oxidoreductase activity
CXP43_RS19250	COG2304	oxidoreductase activity
CXP43_RS19255	COG2385	sporulation resulting in formation of a cellular spore
CXP43_RS19260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CXP43_RS19270	COG4836	Membrane
CXP43_RS19340	COG0698	ribose 5-phosphate isomerase
CXP43_RS19345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXP43_RS19355	COG0009	L-threonylcarbamoyladenylate synthase
CXP43_RS19360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CXP43_RS19380	COG2890	protein-(glutamine-N5) methyltransferase activity
CXP43_RS19385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CXP43_RS19390	COG0346	lactoylglutathione lyase activity
CXP43_RS19395	COG0789	Transcriptional regulator
CXP43_RS19400	COG0679	Auxin Efflux Carrier
CXP43_RS19405	COG0281	malic enzyme
CXP43_RS19420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CXP43_RS19425	COG1494	fructose-1,6-bisphosphatase
CXP43_RS19430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CXP43_RS19440	COG0191	fructose-bisphosphate aldolase activity
CXP43_RS19445	COG2204	response regulator
CXP43_RS19450	COG4821	SIS domain
CXP43_RS19465	COG2181	nitrate reductase activity
CXP43_RS19465	COG0247	lactate metabolic process
CXP43_RS19470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXP43_RS19485	COG1132	(ABC) transporter
CXP43_RS19490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXP43_RS19500	COG2181	nitrate reductase activity
CXP43_RS19505	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXP43_RS19510	COG1140	nitrate reductase beta subunit
CXP43_RS19515	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXP43_RS19520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXP43_RS19530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXP43_RS19535	COG2223	nitrite transmembrane transporter activity
CXP43_RS19545	COG4506	Protein conserved in bacteria
CXP43_RS19550	COG0457	Tetratricopeptide repeat
CXP43_RS19595	COG0010	Belongs to the arginase family
CXP43_RS19600	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CXP43_RS19605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXP43_RS19620	COG1994	Peptidase M50
CXP43_RS19625	COG1942	4-Oxalocrotonate Tautomerase
CXP43_RS19630	COG1846	Transcriptional regulator
CXP43_RS19640	COG0531	amino acid
CXP43_RS19645	COG3465	dGTPase activity
CXP43_RS19650	COG1078	dGTPase activity
CXP43_RS19665	COG1695	Transcriptional regulator
CXP43_RS19675	COG1131	(ABC) transporter
CXP43_RS19680	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CXP43_RS19710	COG0583	DNA-binding transcription factor activity
CXP43_RS19715	COG2855	membrane
CXP43_RS19720	COG0280	phosphate acetyltransferase
CXP43_RS19730	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS19735	COG0436	Aminotransferase
CXP43_RS19765	COG2814	Major facilitator Superfamily
CXP43_RS19770	COG2814	Major facilitator Superfamily
CXP43_RS19775	COG0833	amino acid
CXP43_RS19780	COG4187	Peptidase family M20/M25/M40
CXP43_RS19785	COG1012	belongs to the aldehyde dehydrogenase family
CXP43_RS19790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXP43_RS19795	COG2205	protein histidine kinase activity
CXP43_RS19800	COG0745	RESPONSE REGULATOR receiver
CXP43_RS19815	COG1131	(ABC) transporter
CXP43_RS19820	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CXP43_RS19825	COG1091	dTDP-4-dehydrorhamnose reductase activity
CXP43_RS19830	COG1088	dTDP-glucose 4,6-dehydratase activity
CXP43_RS19835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CXP43_RS19840	COG3980	spore coat polysaccharide biosynthesis protein
CXP43_RS19845	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CXP43_RS19850	COG2089	acid synthase
CXP43_RS19855	COG0456	acetyltransferase
CXP43_RS19860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXP43_RS19865	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CXP43_RS19870	COG0463	Glycosyl transferase, family 2
CXP43_RS19880	COG2363	Small membrane protein
CXP43_RS19885	COG2233	PERMEase
CXP43_RS19900	COG1216	Glycosyl transferase, family 2
CXP43_RS19915	COG1695	Transcriptional regulator
CXP43_RS19920	COG0351	phosphomethylpyrimidine kinase
CXP43_RS19930	COG1621	beta-fructofuranosidase activity
CXP43_RS19935	COG1263	PTS System
CXP43_RS19935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXP43_RS19940	COG3711	transcriptional antiterminator
CXP43_RS19950	COG1404	Belongs to the peptidase S8 family
CXP43_RS19955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXP43_RS19960	COG0778	Nitroreductase
CXP43_RS19965	COG0772	Belongs to the SEDS family
CXP43_RS19970	COG0454	-acetyltransferase
CXP43_RS19990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXP43_RS19995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CXP43_RS20000	COG2261	transglycosylase associated protein
CXP43_RS20005	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CXP43_RS20010	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CXP43_RS20015	COG2246	polysaccharide biosynthetic process
CXP43_RS20020	COG1309	transcriptional regulator
CXP43_RS20040	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CXP43_RS20045	COG2837	iron assimilation
CXP43_RS20050	COG2822	iron ion transport
CXP43_RS20065	COG0583	DNA-binding transcription factor activity
CXP43_RS20075	COG1346	cytolysis
CXP43_RS20080	COG4895	conserved protein (DUF2196)
CXP43_RS20085	COG0789	Transcriptional regulator
CXP43_RS20095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CXP43_RS20100	COG0346	lactoylglutathione lyase activity
CXP43_RS20105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXP43_RS20110	COG1404	Belongs to the peptidase S8 family
CXP43_RS20115	COG1442	glycosyl transferase family 8
CXP43_RS20120	COG1846	Transcriptional regulator
CXP43_RS20125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CXP43_RS20130	COG2357	RelA SpoT domain protein
CXP43_RS20135	COG1575	Belongs to the MenA family. Type 1 subfamily
CXP43_RS20155	COG1696	Membrane protein involved in D-alanine export
CXP43_RS20165	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CXP43_RS20170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXP43_RS20175	COG1486	melibiose metabolic process
CXP43_RS20180	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXP43_RS20185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXP43_RS20190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXP43_RS20195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXP43_RS20195	COG3711	transcriptional antiterminator
CXP43_RS20210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXP43_RS20215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXP43_RS20225	COG0640	Transcriptional regulator
CXP43_RS20230	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXP43_RS20235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXP43_RS20240	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXP43_RS20245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXP43_RS20250	COG2723	6-phospho-beta-galactosidase activity
CXP43_RS20255	COG1940	carbohydrate kinase activity
CXP43_RS20260	COG1482	cell wall glycoprotein biosynthetic process
CXP43_RS20270	COG0753	catalase activity
CXP43_RS20275	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CXP43_RS20280	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CXP43_RS20285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CXP43_RS20290	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CXP43_RS20295	COG4988	ABC transporter
CXP43_RS20300	COG1294	oxidase, subunit
CXP43_RS20305	COG1271	oxidase subunit
CXP43_RS20310	COG3493	citrate carrier protein
CXP43_RS20315	COG0726	polysaccharide deacetylase
CXP43_RS20320	COG3842	ATPase activity
CXP43_RS20325	COG2508	Transcriptional regulator
CXP43_RS20330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXP43_RS20340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXP43_RS20350	COG4894	glucomannan catabolic process
CXP43_RS20355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CXP43_RS20360	COG0500	methyltransferase
CXP43_RS20365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXP43_RS20385	COG0693	protein deglycase activity
CXP43_RS20385	COG0753	catalase activity
CXP43_RS20390	COG2851	Citrate transporter
CXP43_RS20395	COG2273	Hydrolase Family 16
CXP43_RS20400	COG3711	transcriptional antiterminator
CXP43_RS20405	COG2270	Major facilitator Superfamily
CXP43_RS20410	COG0513	Belongs to the DEAD box helicase family
CXP43_RS20460	COG3209	COG3209 Rhs family protein
CXP43_RS20470	COG0697	spore germination
CXP43_RS20475	COG0589	response to stress
CXP43_RS20485	COG0494	nUDIX hydrolase
CXP43_RS20490	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CXP43_RS20495	COG3507	Belongs to the glycosyl hydrolase 43 family
CXP43_RS20520	COG0010	Belongs to the arginase family
CXP43_RS20525	COG0833	amino acid
CXP43_RS20530	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CXP43_RS20535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXP43_RS20545	COG2390	Transcriptional regulator
CXP43_RS20550	COG0561	phosphatase activity
CXP43_RS20580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXP43_RS20585	COG5294	Protein conserved in bacteria
CXP43_RS20590	COG0577	efflux transmembrane transporter activity
CXP43_RS20595	COG1136	(ABC) transporter
CXP43_RS20600	COG2205	protein histidine kinase activity
CXP43_RS20605	COG0745	RESPONSE REGULATOR receiver
CXP43_RS20610	COG2205	protein histidine kinase activity
CXP43_RS20615	COG0745	RESPONSE REGULATOR receiver
CXP43_RS20640	COG0745	RESPONSE REGULATOR receiver
CXP43_RS20670	COG1082	Xylose isomerase domain protein TIM barrel
CXP43_RS20680	COG2814	Major facilitator Superfamily
CXP43_RS20710	COG1349	DNA-binding transcription factor activity
CXP43_RS20715	COG0667	Aldo Keto reductase
CXP43_RS20720	COG2814	Major facilitator Superfamily
CXP43_RS20735	COG1028	Short-chain dehydrogenase reductase Sdr
CXP43_RS20740	COG2197	response regulator
CXP43_RS20745	COG4585	Histidine kinase
CXP43_RS20750	COG3239	Fatty acid desaturase
CXP43_RS20760	COG1309	transcriptional regulator
CXP43_RS20765	COG1012	belongs to the aldehyde dehydrogenase family
CXP43_RS20770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXP43_RS20780	COG0640	Transcriptional regulator
CXP43_RS20790	COG1714	RDD family
CXP43_RS20800	COG0450	alkyl hydroperoxide reductase
CXP43_RS20805	COG3634	alkyl hydroperoxide reductase activity
CXP43_RS20810	COG3177	Filamentation induced by cAMP protein fic
CXP43_RS20815	COG1113	amino acid transport
CXP43_RS20825	COG2080	2 iron, 2 sulfur cluster binding
CXP43_RS20840	COG2068	MobA-Related Protein
CXP43_RS20845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CXP43_RS20910	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CXP43_RS20915	COG0667	Aldo Keto reductase
CXP43_RS20920	COG0456	acetyltransferase
CXP43_RS20925	COG0457	Tetratricopeptide repeat
CXP43_RS20930	COG0010	Belongs to the arginase family
CXP43_RS20935	COG0833	amino acid
CXP43_RS20940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXP43_RS20945	COG3829	transcription factor binding
CXP43_RS20955	COG0488	(ABC) transporter
CXP43_RS20970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXP43_RS20975	COG3850	Histidine kinase
CXP43_RS20975	COG5002	protein histidine kinase activity
CXP43_RS20980	COG0745	RESPONSE REGULATOR receiver
CXP43_RS20990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXP43_RS20995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CXP43_RS21000	COG4853	Protein conserved in bacteria
CXP43_RS21005	COG4863	YycH protein
CXP43_RS21010	COG5002	protein histidine kinase activity
CXP43_RS21015	COG0745	RESPONSE REGULATOR receiver
CXP43_RS21050	COG0346	lactoylglutathione lyase activity
CXP43_RS21055	COG0305	Participates in initiation and elongation during chromosome replication
CXP43_RS21070	COG3093	addiction module antidote protein HigA
CXP43_RS21075	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CXP43_RS21080	COG0297	glycogen (starch) synthase activity
CXP43_RS21090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CXP43_RS21095	COG0438	transferase activity, transferring glycosyl groups
CXP43_RS21105	COG2112	serine threonine protein kinase
CXP43_RS21115	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CXP43_RS21120	COG4241	membrane
CXP43_RS21130	COG5577	PFAM Coat F domain
CXP43_RS21135	COG1733	regulation of RNA biosynthetic process
CXP43_RS21145	COG0697	spore germination
CXP43_RS21150	COG1621	beta-fructofuranosidase activity
CXP43_RS21155	COG1621	beta-fructofuranosidase activity
CXP43_RS21160	COG1802	Transcriptional regulator
CXP43_RS21165	COG2318	DinB family
CXP43_RS21170	COG2211	Major facilitator Superfamily
CXP43_RS21175	COG0697	spore germination
CXP43_RS21185	COG0778	Nitroreductase
CXP43_RS21190	COG1846	Transcriptional regulator
CXP43_RS21195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXP43_RS21200	COG1846	Transcriptional regulator
CXP43_RS21205	COG2153	protein acetylation
CXP43_RS21215	COG0546	phosphoglycolate phosphatase activity
CXP43_RS21245	COG1404	Belongs to the peptidase S8 family
CXP43_RS21255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXP43_RS21260	COG0697	spore germination
CXP43_RS21265	COG1331	Highly conserved protein containing a thioredoxin domain
CXP43_RS21270	COG1266	CAAX protease self-immunity
CXP43_RS21275	COG0477	Major facilitator Superfamily
CXP43_RS21275	COG2814	Major facilitator Superfamily
CXP43_RS21280	COG0346	lactoylglutathione lyase activity
CXP43_RS21285	COG1609	Transcriptional regulator
CXP43_RS21295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXP43_RS21300	COG2169	Transcriptional regulator
CXP43_RS21310	COG0629	single-stranded DNA binding
CXP43_RS21320	COG0012	GTP binding
CXP43_RS21325	COG0243	molybdopterin cofactor binding
CXP43_RS21330	COG4481	Protein conserved in bacteria
CXP43_RS21335	COG3949	Membrane
CXP43_RS21350	COG1475	DNA binding
CXP43_RS21355	COG1192	Involved in chromosome partitioning
CXP43_RS21380	COG1847	R3H domain protein
CXP43_RS21385	COG0706	membrane insertase activity