locus-tag	class	description
H1Q60_RS00020	COG1846	Transcriptional regulator
H1Q60_RS00025	COG4698	Protein conserved in bacteria
H1Q60_RS00030	COG2755	lipolytic protein G-D-S-L family
H1Q60_RS00035	COG1999	signal sequence binding
H1Q60_RS00045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1Q60_RS00050	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H1Q60_RS00055	COG1272	protein, Hemolysin III
H1Q60_RS00060	COG0204	Acyl-transferase
H1Q60_RS00065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1Q60_RS00080	COG2136	Putative SAM-dependent methyltransferase
H1Q60_RS00080	COG2521	methyltransferase
H1Q60_RS00095	COG1413	lyase activity
H1Q60_RS00100	COG1418	mRNA catabolic process
H1Q60_RS00105	COG0386	Belongs to the glutathione peroxidase family
H1Q60_RS00115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H1Q60_RS00125	COG1278	Cold shock
H1Q60_RS00145	COG0328	RNA-DNA hybrid ribonuclease activity
H1Q60_RS00150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H1Q60_RS00155	COG0328	RNA-DNA hybrid ribonuclease activity
H1Q60_RS00165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1Q60_RS00180	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H1Q60_RS00200	COG1335	isochorismatase
H1Q60_RS00205	COG2233	PERMEase
H1Q60_RS00215	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H1Q60_RS00220	COG1199	ATP-dependent helicase activity
H1Q60_RS00235	COG0116	Belongs to the methyltransferase superfamily
H1Q60_RS00265	COG3359	exonuclease
H1Q60_RS00270	COG1205	dead DEAH box helicase
H1Q60_RS00270	COG1111	helicase
H1Q60_RS00275	COG2190	(PTS) system
H1Q60_RS00280	COG0071	Belongs to the small heat shock protein (HSP20) family
H1Q60_RS00320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1Q60_RS00320	COG4499	WXG100 protein secretion system (Wss), protein YukC
H1Q60_RS00330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1Q60_RS00335	COG3935	DnaD domain protein
H1Q60_RS00345	COG0436	Aminotransferase
H1Q60_RS00350	COG5353	protein conserved in bacteria
H1Q60_RS00360	COG1199	ATP-dependent helicase activity
H1Q60_RS00360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1Q60_RS00390	COG0438	transferase activity, transferring glycosyl groups
H1Q60_RS00395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H1Q60_RS00410	COG1694	Mazg nucleotide pyrophosphohydrolase
H1Q60_RS00415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1Q60_RS00420	COG2140	Oxalate decarboxylase
H1Q60_RS00430	COG4347	Protein of unknown function (DUF1405)
H1Q60_RS00435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H1Q60_RS00435	COG2010	Cytochrome c
H1Q60_RS00440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H1Q60_RS00445	COG0723	plastoquinol--plastocyanin reductase activity
H1Q60_RS00460	COG0457	Tetratricopeptide repeat
H1Q60_RS00470	COG0287	Prephenate dehydrogenase
H1Q60_RS00505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1Q60_RS00510	COG4401	Chorismate mutase type I
H1Q60_RS00525	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H1Q60_RS00530	COG0105	UTP biosynthetic process
H1Q60_RS00535	COG0142	geranyltranstransferase activity
H1Q60_RS00545	COG0142	geranyltranstransferase activity
H1Q60_RS00560	COG0776	regulation of translation
H1Q60_RS00565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H1Q60_RS00605	COG0539	negative regulation of cytoplasmic translation
H1Q60_RS00620	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H1Q60_RS00625	COG2959	enzyme of heme biosynthesis
H1Q60_RS00630	COG3409	Peptidoglycan-binding domain 1 protein
H1Q60_RS00630	COG3773	Cell wall hydrolase
H1Q60_RS00635	COG2339	peptidase activity
H1Q60_RS00640	COG0492	ferredoxin-NADP+ reductase activity
H1Q60_RS00645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1Q60_RS00650	COG4862	establishment of competence for transformation
H1Q60_RS00655	COG1408	metallophosphoesterase
H1Q60_RS00665	COG1388	LysM domain
H1Q60_RS00670	COG1266	CAAX protease self-immunity
H1Q60_RS00675	COG0514	ATP-dependent DNA helicase (RecQ)
H1Q60_RS00680	COG4955	Helix-turn-helix domain
H1Q60_RS00685	COG1141	Ferredoxin
H1Q60_RS00690	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H1Q60_RS00695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1Q60_RS00705	COG1595	DNA-templated transcription, initiation
H1Q60_RS00710	COG5002	protein histidine kinase activity
H1Q60_RS00715	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS00720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H1Q60_RS00725	COG1333	cytochrome c biogenesis protein
H1Q60_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q60_RS00735	COG1187	pseudouridine synthase activity
H1Q60_RS00740	COG0700	Nucleoside recognition
H1Q60_RS00745	COG2715	membrane protein required for spore maturation
H1Q60_RS00750	COG1686	Belongs to the peptidase S11 family
H1Q60_RS00775	COG1547	Domain of unknown function (DUF309)
H1Q60_RS00780	COG0456	acetyltransferase
H1Q60_RS00795	COG0307	riboflavin synthase, alpha
H1Q60_RS00800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1Q60_RS00800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1Q60_RS00810	COG0681	Belongs to the peptidase S26 family
H1Q60_RS00820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1Q60_RS00825	COG4086	secreted protein
H1Q60_RS00830	COG0019	diaminopimelate decarboxylase activity
H1Q60_RS00835	COG0697	spore germination
H1Q60_RS00850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H1Q60_RS00870	COG1191	sigma factor activity
H1Q60_RS00880	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q60_RS00885	COG1686	Belongs to the peptidase S11 family
H1Q60_RS00890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H1Q60_RS00895	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H1Q60_RS00900	COG4974	Belongs to the 'phage' integrase family
H1Q60_RS00910	COG0735	belongs to the Fur family
H1Q60_RS00915	COG1300	Membrane
H1Q60_RS00930	COG0281	malic enzyme
H1Q60_RS00935	COG1757	Na H antiporter
H1Q60_RS00940	COG1027	Aspartate ammonia-lyase
H1Q60_RS00945	COG0252	asparaginase activity
H1Q60_RS00950	COG1396	sequence-specific DNA binding
H1Q60_RS00955	COG1379	DNA repair
H1Q60_RS00960	COG0494	nUDIX hydrolase
H1Q60_RS00970	COG0667	Aldo Keto reductase
H1Q60_RS00980	COG1073	alpha beta
H1Q60_RS00990	COG4918	Iron-sulphur cluster biosynthesis
H1Q60_RS00995	COG0456	acetyltransferase
H1Q60_RS00995	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1Q60_RS01000	COG2329	Antibiotic biosynthesis monooxygenase
H1Q60_RS01005	COG0456	acetyltransferase
H1Q60_RS01010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1Q60_RS01025	COG0628	permease
H1Q60_RS01035	COG0346	lactoylglutathione lyase activity
H1Q60_RS01045	COG3048	D-serine ammonia-lyase activity
H1Q60_RS01050	COG0300	oxidoreductase activity
H1Q60_RS01055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q60_RS01060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H1Q60_RS01065	COG1024	Enoyl-CoA hydratase
H1Q60_RS01070	COG3425	synthase
H1Q60_RS01075	COG2124	cytochrome p450
H1Q60_RS01080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1Q60_RS01080	COG3321	synthase
H1Q60_RS01080	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS01080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS01080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q60_RS01085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q60_RS01085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS01085	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS01085	COG3321	synthase
H1Q60_RS01085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1Q60_RS01090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS01090	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q60_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS01090	COG0300	oxidoreductase activity
H1Q60_RS01090	COG3321	synthase
H1Q60_RS01095	COG3321	synthase
H1Q60_RS01095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS01095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q60_RS01095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1Q60_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS01105	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q60_RS01120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1Q60_RS01120	COG2070	2-Nitropropane dioxygenase
H1Q60_RS01125	COG0250	Participates in transcription elongation, termination and antitermination
H1Q60_RS01150	COG0596	Alpha beta hydrolase
H1Q60_RS01165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H1Q60_RS01170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H1Q60_RS01185	COG0706	membrane insertase activity
H1Q60_RS01190	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1Q60_RS01195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1Q60_RS01200	COG0346	lactoylglutathione lyase activity
H1Q60_RS01210	COG1376	ErfK ybiS ycfS ynhG family protein
H1Q60_RS01215	COG4129	membrane
H1Q60_RS01220	COG1126	abc transporter atp-binding protein
H1Q60_RS01225	COG0765	amino acid transport
H1Q60_RS01230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q60_RS01240	COG1597	lipid kinase activity
H1Q60_RS01245	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q60_RS01250	COG0022	dehydrogenase e1 component
H1Q60_RS01255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1Q60_RS01260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1Q60_RS01265	COG3426	butyrate kinase activity
H1Q60_RS01270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1Q60_RS01275	COG0280	phosphate acetyltransferase
H1Q60_RS01280	COG3290	protein histidine kinase activity
H1Q60_RS01280	COG3829	transcription factor binding
H1Q60_RS01290	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H1Q60_RS01295	COG2079	MmgE PrpD family protein
H1Q60_RS01300	COG0372	Belongs to the citrate synthase family
H1Q60_RS01305	COG1960	acyl-CoA dehydrogenase activity
H1Q60_RS01310	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1Q60_RS01315	COG0183	Belongs to the thiolase family
H1Q60_RS01320	COG0584	glycerophosphoryl diester phosphodiesterase
H1Q60_RS01325	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Q60_RS01350	COG1902	pentaerythritol trinitrate reductase activity
H1Q60_RS01365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1Q60_RS01370	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS01375	COG0750	zinc metalloprotease
H1Q60_RS01380	COG0497	DNA recombination
H1Q60_RS01390	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H1Q60_RS01400	COG0142	geranyltranstransferase activity
H1Q60_RS01410	COG1570	exodeoxyribonuclease VII activity
H1Q60_RS01425	COG1302	Protein conserved in bacteria
H1Q60_RS01430	COG0439	Biotin carboxylase
H1Q60_RS01435	COG0511	ligase activity, forming carbon-carbon bonds
H1Q60_RS01475	COG3854	ATPases associated with a variety of cellular activities
H1Q60_RS01490	COG0006	proline dipeptidase activity
H1Q60_RS01500	COG3872	metal-dependent enzyme
H1Q60_RS01510	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1Q60_RS01525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1Q60_RS01545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H1Q60_RS01560	COG1396	sequence-specific DNA binding
H1Q60_RS01570	COG0681	Belongs to the peptidase S26 family
H1Q60_RS01595	COG4940	Competence protein ComGF
H1Q60_RS01605	COG4970	Tfp pilus assembly protein FimT
H1Q60_RS01610	COG4537	Required for transformation and DNA binding
H1Q60_RS01615	COG1459	type II secretion system
H1Q60_RS01620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1Q60_RS01625	COG0598	Magnesium transport protein CorA
H1Q60_RS01630	COG1253	flavin adenine dinucleotide binding
H1Q60_RS01635	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q60_RS01645	COG1393	Belongs to the ArsC family
H1Q60_RS01655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q60_RS01665	COG0011	TIGRFAM Protein of
H1Q60_RS01675	COG2866	Carboxypeptidase
H1Q60_RS01680	COG1940	carbohydrate kinase activity
H1Q60_RS01685	COG4483	Protein conserved in bacteria
H1Q60_RS01690	COG1757	Na H antiporter
H1Q60_RS01700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1Q60_RS01715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1Q60_RS01720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1Q60_RS01725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1Q60_RS01730	COG0581	inorganic phosphate transmembrane transporter activity
H1Q60_RS01735	COG0573	inorganic phosphate transmembrane transporter activity
H1Q60_RS01740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1Q60_RS01750	COG0477	Major facilitator Superfamily
H1Q60_RS01755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1Q60_RS01760	COG2839	Protein conserved in bacteria
H1Q60_RS01765	COG5521	maltodextrose utilization protein MalA
H1Q60_RS01770	COG1388	LysM domain
H1Q60_RS01780	COG4709	membrane
H1Q60_RS01785	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
H1Q60_RS01790	COG0735	belongs to the Fur family
H1Q60_RS01795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1Q60_RS01810	COG0513	Belongs to the DEAD box helicase family
H1Q60_RS01825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1Q60_RS01830	COG2384	SAM-dependent methyltransferase
H1Q60_RS01835	COG2010	Cytochrome c
H1Q60_RS01840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1Q60_RS01845	COG0358	DNA primase activity
H1Q60_RS01860	COG0517	IMP dehydrogenase activity
H1Q60_RS01865	COG0751	glycine-tRNA ligase activity
H1Q60_RS01885	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1Q60_RS01890	COG0295	cytidine deaminase activity
H1Q60_RS01895	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H1Q60_RS01905	COG1480	7TM receptor with intracellular HD hydrolase
H1Q60_RS01910	COG1702	phosphate starvation-inducible protein PhoH
H1Q60_RS01915	COG0561	phosphatase activity
H1Q60_RS01930	COG4864	UPF0365 protein
H1Q60_RS01935	COG1030	water channel activity
H1Q60_RS01940	COG1610	YqeY-like protein
H1Q60_RS01950	COG1283	sodium-dependent phosphate transmembrane transporter activity
H1Q60_RS01955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H1Q60_RS01960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1Q60_RS01990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1Q60_RS02005	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Q60_RS02020	COG1466	dna polymerase III delta subunit
H1Q60_RS02035	COG0658	competence protein
H1Q60_RS02035	COG2333	competence protein COMEC
H1Q60_RS02040	COG2131	deaminase
H1Q60_RS02045	COG1555	photosystem II stabilization
H1Q60_RS02045	COG1596	polysaccharide export
H1Q60_RS02050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H1Q60_RS02055	COG2226	methyltransferase
H1Q60_RS02060	COG0799	negative regulation of ribosome biogenesis
H1Q60_RS02065	COG1713	HD superfamily hydrolase involved in NAD metabolism
H1Q60_RS02075	COG1534	Rna-binding protein
H1Q60_RS02080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H1Q60_RS02085	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H1Q60_RS02090	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H1Q60_RS02100	COG2755	lipolytic protein G-D-S-L family
H1Q60_RS02110	COG0398	Pfam SNARE associated Golgi protein
H1Q60_RS02140	COG5444	nuclease activity
H1Q60_RS02145	COG4282	regulation of fungal-type cell wall biogenesis
H1Q60_RS02165	COG0583	DNA-binding transcription factor activity
H1Q60_RS02180	COG0642	Histidine kinase
H1Q60_RS02180	COG5002	protein histidine kinase activity
H1Q60_RS02185	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS02190	COG2311	Membrane
H1Q60_RS02195	COG0454	-acetyltransferase
H1Q60_RS02200	COG0563	adenylate kinase activity
H1Q60_RS02230	COG5444	nuclease activity
H1Q60_RS02250	COG3328	transposase activity
H1Q60_RS02265	COG0456	acetyltransferase
H1Q60_RS02270	COG2318	DinB family
H1Q60_RS02280	COG0561	phosphatase activity
H1Q60_RS02285	COG0561	phosphatase activity
H1Q60_RS02295	COG1482	cell wall glycoprotein biosynthetic process
H1Q60_RS02300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Q60_RS02300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Q60_RS02300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q60_RS02305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q60_RS02305	COG3711	transcriptional antiterminator
H1Q60_RS02315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1Q60_RS02320	COG0583	DNA-binding transcription factor activity
H1Q60_RS02325	COG2814	Major facilitator Superfamily
H1Q60_RS02330	COG2124	cytochrome p450
H1Q60_RS02330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1Q60_RS02335	COG1309	transcriptional regulator
H1Q60_RS02340	COG2226	methyltransferase
H1Q60_RS02355	COG2116	formate transmembrane transporter activity
H1Q60_RS02360	COG5609	conserved protein (DUF2294)
H1Q60_RS02365	COG3383	formate dehydrogenase (NAD+) activity
H1Q60_RS02370	COG2427	Protein of unknown function (DUF1641)
H1Q60_RS02380	COG0626	cystathionine gamma-synthase activity
H1Q60_RS02385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1Q60_RS02410	COG0768	penicillin binding
H1Q60_RS02435	COG4122	O-methyltransferase activity
H1Q60_RS02440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1Q60_RS02455	COG4472	Bacterial protein of unknown function (DUF965)
H1Q60_RS02465	COG0628	permease
H1Q60_RS02470	COG1126	abc transporter atp-binding protein
H1Q60_RS02475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q60_RS02480	COG0765	amino acid transport
H1Q60_RS02485	COG0765	amino acid transport
H1Q60_RS02500	COG3881	PFAM PRC-barrel domain
H1Q60_RS02505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1Q60_RS02510	COG0457	Tetratricopeptide repeat
H1Q60_RS02520	COG1104	cysteine desulfurase activity
H1Q60_RS02525	COG1959	2 iron, 2 sulfur cluster binding
H1Q60_RS02530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1Q60_RS02535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1Q60_RS02560	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Q60_RS02560	COG3103	Sh3 type 3 domain protein
H1Q60_RS02560	COG4991	sh3 domain protein
H1Q60_RS02570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1Q60_RS02580	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H1Q60_RS02580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1Q60_RS02585	COG5416	Lipopolysaccharide assembly protein A domain
H1Q60_RS02590	COG0490	domain, Protein
H1Q60_RS02595	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1Q60_RS02595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1Q60_RS02605	COG2244	polysaccharide biosynthetic process
H1Q60_RS02610	COG2323	membrane
H1Q60_RS02620	COG1862	Preprotein translocase
H1Q60_RS02660	COG1388	LysM domain
H1Q60_RS02670	COG0157	Belongs to the NadC ModD family
H1Q60_RS02675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H1Q60_RS02680	COG1104	cysteine desulfurase activity
H1Q60_RS02685	COG1827	regulation of RNA biosynthetic process
H1Q60_RS02690	COG0077	Prephenate dehydratase
H1Q60_RS02705	COG3290	protein histidine kinase activity
H1Q60_RS02710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H1Q60_RS02715	COG2868	ribosomal protein
H1Q60_RS02725	COG1994	Peptidase M50
H1Q60_RS02730	COG0739	heme binding
H1Q60_RS02735	COG2894	cell division
H1Q60_RS02745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1Q60_RS02755	COG1077	Cell shape determining protein MreB Mrl
H1Q60_RS02775	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H1Q60_RS02780	COG0285	dihydrofolate synthase activity
H1Q60_RS02785	COG0525	valine-tRNA ligase activity
H1Q60_RS02795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1Q60_RS02800	COG1388	LysM domain
H1Q60_RS02810	COG0113	porphobilinogen synthase activity
H1Q60_RS02815	COG1587	Uroporphyrinogen-III synthase
H1Q60_RS02825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H1Q60_RS02845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H1Q60_RS02850	COG0470	DNA polymerase III
H1Q60_RS02850	COG1067	ATP-dependent peptidase activity
H1Q60_RS02865	COG0457	Tetratricopeptide repeat
H1Q60_RS02865	COG1477	protein flavinylation
H1Q60_RS02880	COG0473	3-isopropylmalate dehydrogenase activity
H1Q60_RS02895	COG0440	acetolactate synthase activity
H1Q60_RS02900	COG0028	Belongs to the TPP enzyme family
H1Q60_RS02930	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
H1Q60_RS02955	COG0622	Phosphoesterase
H1Q60_RS02960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H1Q60_RS02970	COG5401	PFAM Sporulation and spore germination
H1Q60_RS02985	COG2197	response regulator
H1Q60_RS02990	COG0824	Thioesterase
H1Q60_RS02995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1Q60_RS03000	COG1053	succinate dehydrogenase
H1Q60_RS03005	COG2009	succinate dehydrogenase
H1Q60_RS03010	COG1719	4-vinyl reductase, 4VR
H1Q60_RS03015	COG0527	aspartate kinase activity
H1Q60_RS03025	COG3118	belongs to the thioredoxin family
H1Q60_RS03030	COG3534	alpha-L-arabinofuranosidase
H1Q60_RS03035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H1Q60_RS03040	COG2086	electron transfer activity
H1Q60_RS03045	COG1024	Enoyl-CoA hydratase
H1Q60_RS03050	COG1309	transcriptional regulator
H1Q60_RS03055	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q60_RS03065	COG3766	membrane
H1Q60_RS03075	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H1Q60_RS03075	COG1796	DNA polymerase
H1Q60_RS03080	COG1286	toxin biosynthetic process
H1Q60_RS03095	COG0072	phenylalanine-tRNA ligase activity
H1Q60_RS03095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1Q60_RS03100	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H1Q60_RS03105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1Q60_RS03115	COG3835	regulator
H1Q60_RS03120	COG0277	FAD linked oxidase domain protein
H1Q60_RS03125	COG0247	lactate metabolic process
H1Q60_RS03130	COG1966	Carbon starvation protein
H1Q60_RS03135	COG3534	alpha-L-arabinofuranosidase
H1Q60_RS03140	COG0395	ABC-type sugar transport system, permease component
H1Q60_RS03145	COG1175	transmembrane transport
H1Q60_RS03150	COG1653	transport
H1Q60_RS03160	COG0647	UMP catabolic process
H1Q60_RS03165	COG0235	Class ii aldolase
H1Q60_RS03170	COG1069	ribulokinase activity
H1Q60_RS03175	COG2160	L-arabinose isomerase activity
H1Q60_RS03180	COG3507	Belongs to the glycosyl hydrolase 43 family
H1Q60_RS03185	COG1363	Peptidase, m42
H1Q60_RS03195	COG3326	Membrane
H1Q60_RS03210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H1Q60_RS03215	COG1346	cytolysis
H1Q60_RS03220	COG1380	Effector of murein hydrolase LrgA
H1Q60_RS03225	COG3279	Response regulator of the LytR AlgR family
H1Q60_RS03230	COG3275	phosphorelay sensor kinase activity
H1Q60_RS03235	COG1011	Hydrolase
H1Q60_RS03250	COG0398	Pfam SNARE associated Golgi protein
H1Q60_RS03255	COG1484	DNA-dependent DNA replication
H1Q60_RS03260	COG3611	Membrane attachment protein
H1Q60_RS03275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1Q60_RS03280	COG1733	regulation of RNA biosynthetic process
H1Q60_RS03285	COG2814	Major facilitator Superfamily
H1Q60_RS03290	COG0656	L-ascorbic acid biosynthetic process
H1Q60_RS03295	COG0237	dephospho-CoA kinase activity
H1Q60_RS03300	COG1971	Probably functions as a manganese efflux pump
H1Q60_RS03305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H1Q60_RS03310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1Q60_RS03310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1Q60_RS03315	COG5002	protein histidine kinase activity
H1Q60_RS03320	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS03330	COG0538	isocitrate dehydrogenase activity
H1Q60_RS03335	COG0372	Belongs to the citrate synthase family
H1Q60_RS03345	COG0457	Tetratricopeptide repeat
H1Q60_RS03350	COG5444	nuclease activity
H1Q60_RS03365	COG3328	transposase activity
H1Q60_RS03390	COG0628	permease
H1Q60_RS03395	COG3030	protein affecting phage T7 exclusion by the F plasmid
H1Q60_RS03400	COG0469	pyruvate kinase activity
H1Q60_RS03420	COG0281	malic enzyme
H1Q60_RS03425	COG0587	DNA-directed DNA polymerase activity
H1Q60_RS03445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H1Q60_RS03455	COG4109	DRTGG domain
H1Q60_RS03465	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS03480	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1Q60_RS03490	COG0827	DNA restriction-modification system
H1Q60_RS03495	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H1Q60_RS03500	COG3874	Sporulation protein YtfJ
H1Q60_RS03510	COG1714	RDD family
H1Q60_RS03515	COG0616	signal peptide processing
H1Q60_RS03520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1Q60_RS03525	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H1Q60_RS03530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1Q60_RS03545	COG1104	cysteine desulfurase activity
H1Q60_RS03550	COG1114	Component of the transport system for branched-chain amino acids
H1Q60_RS03560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H1Q60_RS03565	COG1309	transcriptional regulator
H1Q60_RS03570	COG1956	GAF domain-containing protein
H1Q60_RS03575	COG2199	diguanylate cyclase activity
H1Q60_RS03575	COG2203	Gaf domain
H1Q60_RS03585	COG1012	belongs to the aldehyde dehydrogenase family
H1Q60_RS03590	COG4282	regulation of fungal-type cell wall biogenesis
H1Q60_RS03655	COG0693	protein deglycase activity
H1Q60_RS03670	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H1Q60_RS03675	COG1378	Sugar-specific transcriptional regulator TrmB
H1Q60_RS03695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1Q60_RS03700	COG0454	-acetyltransferase
H1Q60_RS03705	COG0517	IMP dehydrogenase activity
H1Q60_RS03710	COG0123	including yeast histone deacetylase and acetoin utilization protein
H1Q60_RS03715	COG1360	Flagellar Motor Protein
H1Q60_RS03720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H1Q60_RS03725	COG1609	Transcriptional regulator
H1Q60_RS03730	COG1605	Chorismate mutase
H1Q60_RS03730	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H1Q60_RS03735	COG3118	belongs to the thioredoxin family
H1Q60_RS03740	COG4980	gas vesicle protein
H1Q60_RS03745	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H1Q60_RS03755	COG1674	ftsk spoiiie
H1Q60_RS03760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1Q60_RS03770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q60_RS03790	COG1363	Peptidase, m42
H1Q60_RS03795	COG5584	Small secreted protein
H1Q60_RS03800	COG0281	malic enzyme
H1Q60_RS03805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q60_RS03820	COG0510	thiamine kinase activity
H1Q60_RS03825	COG1597	lipid kinase activity
H1Q60_RS03835	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H1Q60_RS03840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1Q60_RS03845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q60_RS03850	COG2252	PERMEase
H1Q60_RS03855	COG4473	ABC transporter
H1Q60_RS03860	COG1131	(ABC) transporter
H1Q60_RS03865	COG1349	DNA-binding transcription factor activity
H1Q60_RS03870	COG1187	pseudouridine synthase activity
H1Q60_RS03875	COG2244	polysaccharide biosynthetic process
H1Q60_RS03880	COG2081	HI0933 family
H1Q60_RS03885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1Q60_RS03895	COG1609	Transcriptional regulator
H1Q60_RS03900	COG1653	transport
H1Q60_RS03905	COG1175	transmembrane transport
H1Q60_RS03910	COG0395	ABC-type sugar transport system, permease component
H1Q60_RS03915	COG1486	melibiose metabolic process
H1Q60_RS03925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1Q60_RS03940	COG2202	Pas domain
H1Q60_RS03940	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q60_RS03945	COG2814	Major facilitator Superfamily
H1Q60_RS03950	COG5522	Integral membrane protein (intg_mem_TP0381)
H1Q60_RS03955	COG0577	efflux transmembrane transporter activity
H1Q60_RS03960	COG1136	(ABC) transporter
H1Q60_RS03965	COG2205	protein histidine kinase activity
H1Q60_RS03970	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS03975	COG0577	efflux transmembrane transporter activity
H1Q60_RS03980	COG1136	(ABC) transporter
H1Q60_RS04000	COG1131	(ABC) transporter
H1Q60_RS04005	COG1725	Transcriptional regulator
H1Q60_RS04015	COG0640	Transcriptional regulator
H1Q60_RS04020	COG0477	Major facilitator Superfamily
H1Q60_RS04025	COG1242	4 iron, 4 sulfur cluster binding
H1Q60_RS04030	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H1Q60_RS04040	COG0584	glycerophosphoryl diester phosphodiesterase
H1Q60_RS04050	COG2267	carboxylic ester hydrolase activity
H1Q60_RS04055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1Q60_RS04060	COG1113	amino acid transport
H1Q60_RS04065	COG0367	asparagine synthase
H1Q60_RS04085	COG1506	peptidase
H1Q60_RS04090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Q60_RS04095	COG1116	anion transmembrane transporter activity
H1Q60_RS04100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q60_RS04105	COG0494	nUDIX hydrolase
H1Q60_RS04110	COG4824	toxin secretion phage lysis holin
H1Q60_RS04115	COG0783	Belongs to the Dps family
H1Q60_RS04140	COG0288	reversible hydration of carbon dioxide
H1Q60_RS04150	COG1271	oxidase subunit
H1Q60_RS04155	COG1294	oxidase, subunit
H1Q60_RS04165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Q60_RS04170	COG1321	iron dependent repressor
H1Q60_RS04170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Q60_RS04175	COG1121	(ABC) transporter
H1Q60_RS04180	COG0803	Belongs to the bacterial solute-binding protein 9 family
H1Q60_RS04185	COG4948	Mandelate Racemase Muconate Lactonizing
H1Q60_RS04195	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H1Q60_RS04200	COG0596	Alpha beta hydrolase
H1Q60_RS04210	COG1169	isochorismate synthase
H1Q60_RS04215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1Q60_RS04220	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
H1Q60_RS04345	COG3859	Proton-coupled thiamine transporter YuaJ
H1Q60_RS04350	COG2268	Band 7 protein
H1Q60_RS04355	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1Q60_RS04360	COG2318	DinB family
H1Q60_RS04370	COG1454	alcohol dehydrogenase
H1Q60_RS04375	COG1012	belongs to the aldehyde dehydrogenase family
H1Q60_RS04380	COG1510	regulation of RNA biosynthetic process
H1Q60_RS04390	COG0569	domain protein
H1Q60_RS04395	COG1705	Flagellar rod assembly protein muramidase FlgJ
H1Q60_RS04400	COG1017	nitric oxide dioxygenase activity
H1Q60_RS04400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1Q60_RS04415	COG0457	Tetratricopeptide repeat
H1Q60_RS04450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1Q60_RS04465	COG0628	permease
H1Q60_RS04470	COG0673	inositol 2-dehydrogenase activity
H1Q60_RS04475	COG0693	protein deglycase activity
H1Q60_RS04480	COG0840	transmembrane signaling receptor activity
H1Q60_RS04485	COG0840	transmembrane signaling receptor activity
H1Q60_RS04490	COG0840	transmembrane signaling receptor activity
H1Q60_RS04495	COG0840	transmembrane signaling receptor activity
H1Q60_RS04510	COG2070	2-Nitropropane dioxygenase
H1Q60_RS04515	COG0432	Pfam Uncharacterised protein family UPF0047
H1Q60_RS04520	COG0366	Alpha amylase catalytic
H1Q60_RS04525	COG1253	flavin adenine dinucleotide binding
H1Q60_RS04530	COG2738	Putative neutral zinc metallopeptidase
H1Q60_RS04545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1Q60_RS04570	COG1335	isochorismatase
H1Q60_RS04585	COG2155	Conserved Protein
H1Q60_RS04595	COG1098	S1 RNA binding domain
H1Q60_RS04600	COG0436	Aminotransferase
H1Q60_RS04605	COG1522	sequence-specific DNA binding
H1Q60_RS04610	COG2267	carboxylic ester hydrolase activity
H1Q60_RS04620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H1Q60_RS04625	COG2205	protein histidine kinase activity
H1Q60_RS04635	COG5018	Exonuclease
H1Q60_RS04640	COG2814	Major facilitator Superfamily
H1Q60_RS04645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1Q60_RS04650	COG3011	Protein conserved in bacteria
H1Q60_RS04660	COG3290	protein histidine kinase activity
H1Q60_RS04665	COG4565	transcriptional regulatory protein
H1Q60_RS04695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1Q60_RS04695	COG2111	Na H antiporter
H1Q60_RS04700	COG2111	Na H antiporter
H1Q60_RS04705	COG1006	Multisubunit Na H antiporter MnhC subunit
H1Q60_RS04710	COG0651	ATP synthesis coupled electron transport
H1Q60_RS04715	COG1863	multisubunit Na H antiporter MnhE subunit
H1Q60_RS04720	COG2212	antiporter activity
H1Q60_RS04725	COG1320	monovalent cation:proton antiporter activity
H1Q60_RS04730	COG2050	protein possibly involved in aromatic compounds catabolism
H1Q60_RS04735	COG2197	response regulator
H1Q60_RS04740	COG4585	Histidine kinase
H1Q60_RS04750	COG0142	geranyltranstransferase activity
H1Q60_RS04765	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H1Q60_RS04770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H1Q60_RS04775	COG1335	isochorismatase
H1Q60_RS04780	COG5506	Protein of unknown function (DUF1694)
H1Q60_RS04795	COG0628	permease
H1Q60_RS04805	COG1418	mRNA catabolic process
H1Q60_RS04810	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS04820	COG1511	domain protein
H1Q60_RS04825	COG1674	ftsk spoiiie
H1Q60_RS04825	COG0433	COG0433 Predicted ATPase
H1Q60_RS04830	COG4499	WXG100 protein secretion system (Wss), protein YukC
H1Q60_RS04835	COG5417	Belongs to the EsaB family
H1Q60_RS04840	COG4842	Belongs to the WXG100 family
H1Q60_RS04845	COG2508	Transcriptional regulator
H1Q60_RS04845	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1Q60_RS04850	COG0686	Belongs to the AlaDH PNT family
H1Q60_RS04855	COG5634	Uncharacterized conserved protein (DUF2278)
H1Q60_RS04860	COG3251	PFAM MbtH domain protein
H1Q60_RS04865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS04870	COG1535	isochorismatase
H1Q60_RS04870	COG3433	isochorismatase activity
H1Q60_RS04875	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1Q60_RS04880	COG1169	isochorismate synthase
H1Q60_RS04885	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS04890	COG2819	hydrolase of the alpha beta superfamily
H1Q60_RS04895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H1Q60_RS04900	COG1268	BioY protein
H1Q60_RS04905	COG2056	Na+-H+ antiporter family
H1Q60_RS04915	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H1Q60_RS04920	COG3584	3D domain protein
H1Q60_RS04935	COG1252	NADH dehydrogenase
H1Q60_RS04965	COG1131	(ABC) transporter
H1Q60_RS04985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Q60_RS04990	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H1Q60_RS04995	COG0316	Belongs to the HesB IscA family
H1Q60_RS05005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1Q60_RS05015	COG1252	NADH dehydrogenase
H1Q60_RS05020	COG4837	Protein of unknown function (DUF1462)
H1Q60_RS05025	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H1Q60_RS05030	COG4946	Tricorn protease homolog
H1Q60_RS05030	COG1506	peptidase
H1Q60_RS05030	COG0823	Involved in the tonB-independent uptake of proteins
H1Q60_RS05040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1Q60_RS05045	COG0460	homoserine dehydrogenase
H1Q60_RS05050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1Q60_RS05055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1Q60_RS05060	COG0647	UMP catabolic process
H1Q60_RS05065	COG2445	Protein of unknown function DUF86
H1Q60_RS05070	COG4470	Protein conserved in bacteria
H1Q60_RS05080	COG0739	heme binding
H1Q60_RS05090	COG0737	Belongs to the 5'-nucleotidase family
H1Q60_RS05095	COG0730	response to heat
H1Q60_RS05100	COG1801	Protein of unknown function DUF72
H1Q60_RS05115	COG2508	Transcriptional regulator
H1Q60_RS05120	COG0457	Tetratricopeptide repeat
H1Q60_RS05130	COG2814	Major facilitator Superfamily
H1Q60_RS05135	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H1Q60_RS05140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q60_RS05145	COG2356	endonuclease I
H1Q60_RS05150	COG3842	ATPase activity
H1Q60_RS05155	COG2188	Transcriptional regulator
H1Q60_RS05160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Q60_RS05165	COG0395	ABC-type sugar transport system, permease component
H1Q60_RS05170	COG1175	transmembrane transport
H1Q60_RS05175	COG1653	transport
H1Q60_RS05180	COG2222	sugar isomerase
H1Q60_RS05185	COG0789	Transcriptional regulator
H1Q60_RS05210	COG0322	excinuclease ABC activity
H1Q60_RS05215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q60_RS05220	COG2226	methyltransferase
H1Q60_RS05230	COG3409	Peptidoglycan-binding domain 1 protein
H1Q60_RS05235	COG0719	Fe-S assembly protein
H1Q60_RS05240	COG0822	iron-sulfur transferase activity
H1Q60_RS05245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1Q60_RS05250	COG0719	Fe-S assembly protein
H1Q60_RS05255	COG0396	ATPase activity
H1Q60_RS05265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Q60_RS05270	COG1464	Belongs to the NlpA lipoprotein family
H1Q60_RS05275	COG2011	ABC-type metal ion transport system permease component
H1Q60_RS05280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1Q60_RS05290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q60_RS05295	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H1Q60_RS05310	COG1393	Belongs to the ArsC family
H1Q60_RS05315	COG1960	acyl-CoA dehydrogenase activity
H1Q60_RS05320	COG0183	Belongs to the thiolase family
H1Q60_RS05325	COG1024	Enoyl-CoA hydratase
H1Q60_RS05325	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1Q60_RS05345	COG5577	PFAM Coat F domain
H1Q60_RS05350	COG1846	Transcriptional regulator
H1Q60_RS05355	COG0477	Major facilitator Superfamily
H1Q60_RS05375	COG1120	ATPase activity
H1Q60_RS05390	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS05395	COG0783	Belongs to the Dps family
H1Q60_RS05400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Q60_RS05405	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS05410	COG2770	Histidine kinase
H1Q60_RS05410	COG2205	protein histidine kinase activity
H1Q60_RS05420	COG1309	transcriptional regulator
H1Q60_RS05425	COG0114	fumarate hydratase activity
H1Q60_RS05435	COG0697	spore germination
H1Q60_RS05440	COG0814	amino acid
H1Q60_RS05450	COG2197	response regulator
H1Q60_RS05455	COG4585	Histidine kinase
H1Q60_RS05460	COG4758	membrane
H1Q60_RS05465	COG3595	metallopeptidase activity
H1Q60_RS05470	COG1842	Phage shock protein A
H1Q60_RS05475	COG4758	membrane
H1Q60_RS05480	COG2814	Major facilitator Superfamily
H1Q60_RS05485	COG2096	Adenosyltransferase
H1Q60_RS05490	COG1120	ATPase activity
H1Q60_RS05495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q60_RS05500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1Q60_RS05505	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS05510	COG3386	PFAM SMP-30 Gluconolaconase
H1Q60_RS05515	COG2205	protein histidine kinase activity
H1Q60_RS05520	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS05530	COG1191	sigma factor activity
H1Q60_RS05540	COG2140	Oxalate decarboxylase
H1Q60_RS05550	COG1120	ATPase activity
H1Q60_RS05555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q60_RS05560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q60_RS05565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1Q60_RS05570	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H1Q60_RS05575	COG0531	amino acid
H1Q60_RS05585	COG1988	membrane-bound metal-dependent
H1Q60_RS05595	COG1910	domain protein
H1Q60_RS05600	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1Q60_RS05605	COG4149	molybdate abc transporter
H1Q60_RS05610	COG2197	response regulator
H1Q60_RS05620	COG1131	(ABC) transporter
H1Q60_RS05630	COG0842	Transport permease protein
H1Q60_RS05635	COG0656	L-ascorbic acid biosynthetic process
H1Q60_RS05655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1Q60_RS05660	COG3973	AAA domain
H1Q60_RS05665	COG2860	membrane
H1Q60_RS05675	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H1Q60_RS05680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1Q60_RS05685	COG2217	Heavy metal translocating P-type atpase
H1Q60_RS05690	COG2217	Heavy metal translocating P-type atpase
H1Q60_RS05695	COG2608	mercury ion transmembrane transporter activity
H1Q60_RS05700	COG1937	Protein conserved in bacteria
H1Q60_RS05705	COG0673	inositol 2-dehydrogenase activity
H1Q60_RS05715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Q60_RS05720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1Q60_RS05725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Q60_RS05730	COG1126	abc transporter atp-binding protein
H1Q60_RS05735	COG0765	amino acid transport
H1Q60_RS05740	COG0765	amino acid transport
H1Q60_RS05745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q60_RS05750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q60_RS05755	COG0454	-acetyltransferase
H1Q60_RS05760	COG0583	DNA-binding transcription factor activity
H1Q60_RS05765	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS05770	COG2732	(Barnase) inhibitor
H1Q60_RS05775	COG2732	(Barnase) inhibitor
H1Q60_RS05790	COG0557	exoribonuclease II activity
H1Q60_RS05795	COG1647	Serine aminopeptidase, S33
H1Q60_RS05800	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H1Q60_RS05805	COG1476	TRANSCRIPTIONal
H1Q60_RS05810	COG1396	sequence-specific DNA binding
H1Q60_RS05815	COG1396	sequence-specific DNA binding
H1Q60_RS05820	COG1733	regulation of RNA biosynthetic process
H1Q60_RS05845	COG1131	(ABC) transporter
H1Q60_RS05850	COG1174	glycine betaine transport
H1Q60_RS05855	COG1732	Glycine betaine
H1Q60_RS05860	COG1174	glycine betaine transport
H1Q60_RS05865	COG0517	IMP dehydrogenase activity
H1Q60_RS05865	COG1125	glycine betaine transport
H1Q60_RS05870	COG1510	regulation of RNA biosynthetic process
H1Q60_RS05875	COG1174	glycine betaine transport
H1Q60_RS05880	COG1732	Glycine betaine
H1Q60_RS05885	COG1174	glycine betaine transport
H1Q60_RS05890	COG0517	IMP dehydrogenase activity
H1Q60_RS05890	COG1125	glycine betaine transport
H1Q60_RS05895	COG1510	regulation of RNA biosynthetic process
H1Q60_RS05900	COG2095	MarC family integral membrane protein
H1Q60_RS05905	COG3064	Membrane
H1Q60_RS05910	COG4640	response to antibiotic
H1Q60_RS05915	COG0456	acetyltransferase
H1Q60_RS05935	COG0126	phosphoglycerate kinase activity
H1Q60_RS05940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1Q60_RS05945	COG2390	Transcriptional regulator
H1Q60_RS05950	COG2814	Major facilitator Superfamily
H1Q60_RS05955	COG1609	Transcriptional regulator
H1Q60_RS05965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Q60_RS05975	COG0583	DNA-binding transcription factor activity
H1Q60_RS05980	COG0697	spore germination
H1Q60_RS05985	COG1113	amino acid transport
H1Q60_RS05990	COG1737	Transcriptional regulator
H1Q60_RS05995	COG1070	Carbohydrate kinase
H1Q60_RS06020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q60_RS06025	COG2186	Transcriptional regulator
H1Q60_RS06030	COG1620	l-lactate permease
H1Q60_RS06035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H1Q60_RS06045	COG5039	Polysaccharide pyruvyl transferase
H1Q60_RS06050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1Q60_RS06055	COG0110	maltose O-acetyltransferase activity
H1Q60_RS06060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1Q60_RS06065	COG2244	polysaccharide biosynthetic process
H1Q60_RS06070	COG1216	Glycosyl transferase, family 2
H1Q60_RS06075	COG5039	Polysaccharide pyruvyl transferase
H1Q60_RS06080	COG1216	Glycosyl transferase, family 2
H1Q60_RS06090	COG0438	transferase activity, transferring glycosyl groups
H1Q60_RS06095	COG1215	transferase activity, transferring glycosyl groups
H1Q60_RS06100	COG0438	transferase activity, transferring glycosyl groups
H1Q60_RS06105	COG1086	Polysaccharide biosynthesis protein
H1Q60_RS06110	COG0489	protein tyrosine kinase activity
H1Q60_RS06115	COG3944	biosynthesis protein
H1Q60_RS06120	COG1396	sequence-specific DNA binding
H1Q60_RS06125	COG2272	Belongs to the type-B carboxylesterase lipase family
H1Q60_RS06135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1Q60_RS06140	COG2364	Membrane
H1Q60_RS06145	COG0456	acetyltransferase
H1Q60_RS06150	COG3479	Phenolic acid decarboxylase
H1Q60_RS06190	COG1357	PFAM Pentapeptide repeats (8 copies)
H1Q60_RS06195	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1Q60_RS06210	COG2223	nitrite transmembrane transporter activity
H1Q60_RS06215	COG1609	Transcriptional regulator
H1Q60_RS06225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1Q60_RS06230	COG0366	Alpha amylase catalytic
H1Q60_RS06235	COG1554	hydrolase, family 65, central catalytic
H1Q60_RS06240	COG5521	maltodextrose utilization protein MalA
H1Q60_RS06245	COG3833	ABC-type maltose transport systems, permease component
H1Q60_RS06250	COG1175	transmembrane transport
H1Q60_RS06255	COG2182	Extracellular solute-binding protein
H1Q60_RS06260	COG0366	Alpha amylase catalytic
H1Q60_RS06265	COG1609	Transcriptional regulator
H1Q60_RS06270	COG1611	Belongs to the LOG family
H1Q60_RS06275	COG1694	Mazg nucleotide pyrophosphohydrolase
H1Q60_RS06280	COG0659	secondary active sulfate transmembrane transporter activity
H1Q60_RS06285	COG0288	reversible hydration of carbon dioxide
H1Q60_RS06290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1Q60_RS06295	COG4290	ribonuclease
H1Q60_RS06300	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H1Q60_RS06305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q60_RS06315	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H1Q60_RS06325	COG1051	belongs to the nudix hydrolase family
H1Q60_RS06330	COG0492	ferredoxin-NADP+ reductase activity
H1Q60_RS06335	COG3883	PFAM NLP P60 protein
H1Q60_RS06335	COG0791	NLP P60 protein
H1Q60_RS06340	COG0457	Tetratricopeptide repeat
H1Q60_RS06345	COG5002	protein histidine kinase activity
H1Q60_RS06350	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS06360	COG1132	(ABC) transporter
H1Q60_RS06365	COG0140	phosphoribosyl-ATP diphosphatase activity
H1Q60_RS06365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1Q60_RS06390	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1Q60_RS06405	COG4990	cell redox homeostasis
H1Q60_RS06410	COG0110	maltose O-acetyltransferase activity
H1Q60_RS06430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H1Q60_RS06440	COG2188	Transcriptional regulator
H1Q60_RS06445	COG1309	transcriptional regulator
H1Q60_RS06450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1Q60_RS06455	COG1950	PFAM Membrane protein of
H1Q60_RS06460	COG1983	PspC domain protein
H1Q60_RS06465	COG3595	metallopeptidase activity
H1Q60_RS06480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1Q60_RS06490	COG4897	Protein conserved in bacteria
H1Q60_RS06495	COG0574	Belongs to the PEP-utilizing enzyme family
H1Q60_RS06495	COG3848	Pyruvate phosphate dikinase
H1Q60_RS06500	COG1309	transcriptional regulator
H1Q60_RS06505	COG2814	Major facilitator Superfamily
H1Q60_RS06515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Q60_RS06525	COG0793	Belongs to the peptidase S41A family
H1Q60_RS06525	COG3409	Peptidoglycan-binding domain 1 protein
H1Q60_RS06530	COG3420	alginic acid biosynthetic process
H1Q60_RS06535	COG2177	Part of the ABC transporter FtsEX involved in
H1Q60_RS06540	COG2884	Cell division ATP-binding protein ftsE
H1Q60_RS06545	COG2010	Cytochrome c
H1Q60_RS06550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1Q60_RS06565	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H1Q60_RS06580	COG1516	flagellar protein fliS
H1Q60_RS06585	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H1Q60_RS06590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H1Q60_RS06610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H1Q60_RS06615	COG1256	bacterial-type flagellum assembly
H1Q60_RS06615	COG4786	Flagellar basal body rod
H1Q60_RS06620	COG3418	PFAM FlgN family protein
H1Q60_RS06625	COG2747	anti-sigma28 factor FlgM
H1Q60_RS06635	COG1040	competence protein
H1Q60_RS06645	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H1Q60_RS06650	COG1307	EDD domain protein, DegV family
H1Q60_RS06655	COG2197	response regulator
H1Q60_RS06660	COG4585	Histidine kinase
H1Q60_RS06665	COG1739	Uncharacterized protein family UPF0029
H1Q60_RS06670	COG1316	TRANSCRIPTIONal
H1Q60_RS06675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1Q60_RS06680	COG0438	transferase activity, transferring glycosyl groups
H1Q60_RS06685	COG1215	transferase activity, transferring glycosyl groups
H1Q60_RS06690	COG3206	protein involved in exopolysaccharide biosynthesis
H1Q60_RS06695	COG3307	-O-antigen
H1Q60_RS06700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H1Q60_RS06705	COG0438	transferase activity, transferring glycosyl groups
H1Q60_RS06705	COG0297	glycogen (starch) synthase activity
H1Q60_RS06710	COG2244	polysaccharide biosynthetic process
H1Q60_RS06720	COG1316	TRANSCRIPTIONal
H1Q60_RS06725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H1Q60_RS06730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1Q60_RS06735	COG1134	teichoic acid transport
H1Q60_RS06740	COG1682	transport, permease protein
H1Q60_RS06745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H1Q60_RS06750	COG0438	transferase activity, transferring glycosyl groups
H1Q60_RS06755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H1Q60_RS06760	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H1Q60_RS06765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H1Q60_RS06770	COG4193	domain, Protein
H1Q60_RS06780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H1Q60_RS06810	COG1482	cell wall glycoprotein biosynthetic process
H1Q60_RS06815	COG0697	spore germination
H1Q60_RS06820	COG0814	amino acid
H1Q60_RS06830	COG1215	transferase activity, transferring glycosyl groups
H1Q60_RS06835	COG2814	Major facilitator Superfamily
H1Q60_RS06840	COG1316	TRANSCRIPTIONal
H1Q60_RS06845	COG0561	phosphatase activity
H1Q60_RS06850	COG2433	Pfam Transposase IS66
H1Q60_RS06855	COG0791	NLP P60 protein
H1Q60_RS06865	COG2843	Capsule synthesis protein
H1Q60_RS06875	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H1Q60_RS06880	COG0697	spore germination
H1Q60_RS06885	COG0814	amino acid
H1Q60_RS06895	COG1609	Transcriptional regulator
H1Q60_RS06900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Q60_RS06910	COG1129	ABC transporter
H1Q60_RS06915	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Q60_RS06920	COG1879	ABC-type sugar transport system periplasmic component
H1Q60_RS06925	COG3103	Sh3 type 3 domain protein
H1Q60_RS06930	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1Q60_RS06935	COG3527	Alpha-acetolactate decarboxylase
H1Q60_RS06940	COG0028	Belongs to the TPP enzyme family
H1Q60_RS06945	COG0583	DNA-binding transcription factor activity
H1Q60_RS06950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1Q60_RS06965	COG5337	Spore coat protein CotH
H1Q60_RS06975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1Q60_RS06985	COG0405	Gamma-glutamyltransferase
H1Q60_RS06990	COG1522	sequence-specific DNA binding
H1Q60_RS06995	COG2059	Chromate
H1Q60_RS07000	COG2059	Chromate
H1Q60_RS07010	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1Q60_RS07015	COG0583	DNA-binding transcription factor activity
H1Q60_RS07055	COG5444	nuclease activity
H1Q60_RS07070	COG3878	Protein conserved in bacteria
H1Q60_RS07075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H1Q60_RS07080	COG4464	protein tyrosine phosphatase activity
H1Q60_RS07085	COG0489	protein tyrosine kinase activity
H1Q60_RS07090	COG3944	biosynthesis protein
H1Q60_RS07100	COG4715	Zinc finger, swim domain protein
H1Q60_RS07105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H1Q60_RS07110	COG0561	phosphatase activity
H1Q60_RS07115	COG1349	DNA-binding transcription factor activity
H1Q60_RS07120	COG0629	single-stranded DNA binding
H1Q60_RS07145	COG0457	Tetratricopeptide repeat
H1Q60_RS07150	COG4786	Flagellar basal body rod
H1Q60_RS07155	COG4786	Flagellar basal body rod
H1Q60_RS07160	COG1077	Cell shape determining protein MreB Mrl
H1Q60_RS07165	COG1609	Transcriptional regulator
H1Q60_RS07170	COG1846	Transcriptional regulator
H1Q60_RS07175	COG2814	Major facilitator Superfamily
H1Q60_RS07180	COG1953	Uracil, thiamine, allantoin
H1Q60_RS07185	COG0477	Major facilitator Superfamily
H1Q60_RS07190	COG1335	isochorismatase
H1Q60_RS07195	COG0004	ammonium transporteR
H1Q60_RS07200	COG0347	Belongs to the P(II) protein family
H1Q60_RS07205	COG0772	Belongs to the SEDS family
H1Q60_RS07210	COG0671	phosphoesterase, PA-phosphatase related
H1Q60_RS07220	COG0739	heme binding
H1Q60_RS07225	COG1247	-acetyltransferase
H1Q60_RS07240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1Q60_RS07250	COG0726	polysaccharide deacetylase
H1Q60_RS07255	COG1959	2 iron, 2 sulfur cluster binding
H1Q60_RS07270	COG0831	urea catabolic process
H1Q60_RS07280	COG1994	Peptidase M50
H1Q60_RS07285	COG0457	Tetratricopeptide repeat
H1Q60_RS07295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1Q60_RS07310	COG2304	oxidoreductase activity
H1Q60_RS07315	COG2385	sporulation resulting in formation of a cellular spore
H1Q60_RS07320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1Q60_RS07330	COG4836	Membrane
H1Q60_RS07400	COG0698	ribose 5-phosphate isomerase
H1Q60_RS07405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1Q60_RS07415	COG0009	L-threonylcarbamoyladenylate synthase
H1Q60_RS07420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H1Q60_RS07440	COG2890	protein-(glutamine-N5) methyltransferase activity
H1Q60_RS07445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H1Q60_RS07450	COG0346	lactoylglutathione lyase activity
H1Q60_RS07455	COG0789	Transcriptional regulator
H1Q60_RS07460	COG0679	Auxin Efflux Carrier
H1Q60_RS07465	COG0281	malic enzyme
H1Q60_RS07480	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H1Q60_RS07485	COG1494	fructose-1,6-bisphosphatase
H1Q60_RS07490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1Q60_RS07500	COG0191	fructose-bisphosphate aldolase activity
H1Q60_RS07505	COG2204	response regulator
H1Q60_RS07510	COG4821	SIS domain
H1Q60_RS07525	COG0247	lactate metabolic process
H1Q60_RS07525	COG2181	nitrate reductase activity
H1Q60_RS07530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1Q60_RS07545	COG1132	(ABC) transporter
H1Q60_RS07550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1Q60_RS07560	COG2181	nitrate reductase activity
H1Q60_RS07565	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H1Q60_RS07570	COG1140	nitrate reductase beta subunit
H1Q60_RS07575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H1Q60_RS07580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q60_RS07590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q60_RS07595	COG2223	nitrite transmembrane transporter activity
H1Q60_RS07605	COG4506	Protein conserved in bacteria
H1Q60_RS07610	COG0457	Tetratricopeptide repeat
H1Q60_RS07620	COG0010	Belongs to the arginase family
H1Q60_RS07625	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H1Q60_RS07630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1Q60_RS07645	COG1994	Peptidase M50
H1Q60_RS07650	COG1942	4-Oxalocrotonate Tautomerase
H1Q60_RS07655	COG1846	Transcriptional regulator
H1Q60_RS07660	COG0531	amino acid
H1Q60_RS07665	COG3465	dGTPase activity
H1Q60_RS07670	COG1078	dGTPase activity
H1Q60_RS07685	COG1695	Transcriptional regulator
H1Q60_RS07695	COG1131	(ABC) transporter
H1Q60_RS07700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H1Q60_RS07730	COG0583	DNA-binding transcription factor activity
H1Q60_RS07735	COG2855	membrane
H1Q60_RS07740	COG0280	phosphate acetyltransferase
H1Q60_RS07750	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS07755	COG0436	Aminotransferase
H1Q60_RS07785	COG2814	Major facilitator Superfamily
H1Q60_RS07790	COG2814	Major facilitator Superfamily
H1Q60_RS07795	COG0833	amino acid
H1Q60_RS07800	COG4187	Peptidase family M20/M25/M40
H1Q60_RS07805	COG1012	belongs to the aldehyde dehydrogenase family
H1Q60_RS07810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1Q60_RS07815	COG2205	protein histidine kinase activity
H1Q60_RS07820	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS07835	COG1131	(ABC) transporter
H1Q60_RS07840	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
H1Q60_RS07845	COG1091	dTDP-4-dehydrorhamnose reductase activity
H1Q60_RS07850	COG1088	dTDP-glucose 4,6-dehydratase activity
H1Q60_RS07855	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H1Q60_RS07860	COG3980	spore coat polysaccharide biosynthesis protein
H1Q60_RS07865	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H1Q60_RS07870	COG2089	acid synthase
H1Q60_RS07875	COG0456	acetyltransferase
H1Q60_RS07880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1Q60_RS07885	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H1Q60_RS07890	COG0463	Glycosyl transferase, family 2
H1Q60_RS07900	COG2363	Small membrane protein
H1Q60_RS07905	COG2233	PERMEase
H1Q60_RS07920	COG1216	Glycosyl transferase, family 2
H1Q60_RS07935	COG1695	Transcriptional regulator
H1Q60_RS07940	COG0351	phosphomethylpyrimidine kinase
H1Q60_RS07950	COG1621	beta-fructofuranosidase activity
H1Q60_RS07955	COG1263	PTS System
H1Q60_RS07955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Q60_RS07960	COG3711	transcriptional antiterminator
H1Q60_RS07970	COG1404	Belongs to the peptidase S8 family
H1Q60_RS07975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Q60_RS07980	COG0778	Nitroreductase
H1Q60_RS07985	COG0772	Belongs to the SEDS family
H1Q60_RS07990	COG0454	-acetyltransferase
H1Q60_RS08010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1Q60_RS08015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1Q60_RS08020	COG2261	transglycosylase associated protein
H1Q60_RS08025	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H1Q60_RS08030	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H1Q60_RS08035	COG2246	polysaccharide biosynthetic process
H1Q60_RS08040	COG1309	transcriptional regulator
H1Q60_RS08060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1Q60_RS08065	COG2837	iron assimilation
H1Q60_RS08070	COG2822	iron ion transport
H1Q60_RS08085	COG0583	DNA-binding transcription factor activity
H1Q60_RS08095	COG1346	cytolysis
H1Q60_RS08100	COG1131	(ABC) transporter
H1Q60_RS08125	COG4895	conserved protein (DUF2196)
H1Q60_RS08130	COG0789	Transcriptional regulator
H1Q60_RS08135	COG5504	Zn-dependent protease
H1Q60_RS08140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H1Q60_RS08145	COG0346	lactoylglutathione lyase activity
H1Q60_RS08150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Q60_RS08155	COG1404	Belongs to the peptidase S8 family
H1Q60_RS08160	COG1442	glycosyl transferase family 8
H1Q60_RS08165	COG2357	RelA SpoT domain protein
H1Q60_RS08170	COG1575	Belongs to the MenA family. Type 1 subfamily
H1Q60_RS08185	COG1696	Membrane protein involved in D-alanine export
H1Q60_RS08195	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H1Q60_RS08200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1Q60_RS08205	COG1486	melibiose metabolic process
H1Q60_RS08210	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1Q60_RS08215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Q60_RS08220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Q60_RS08225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q60_RS08225	COG3711	transcriptional antiterminator
H1Q60_RS08235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q60_RS08240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q60_RS08250	COG0640	Transcriptional regulator
H1Q60_RS08255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1Q60_RS08260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Q60_RS08265	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1Q60_RS08270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Q60_RS08275	COG2723	6-phospho-beta-galactosidase activity
H1Q60_RS08280	COG1940	carbohydrate kinase activity
H1Q60_RS08285	COG1482	cell wall glycoprotein biosynthetic process
H1Q60_RS08295	COG0753	catalase activity
H1Q60_RS08300	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
H1Q60_RS08305	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1Q60_RS08310	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1Q60_RS08315	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H1Q60_RS08320	COG4988	ABC transporter
H1Q60_RS08325	COG1294	oxidase, subunit
H1Q60_RS08330	COG1271	oxidase subunit
H1Q60_RS08335	COG3493	citrate carrier protein
H1Q60_RS08340	COG0726	polysaccharide deacetylase
H1Q60_RS08345	COG3842	ATPase activity
H1Q60_RS08350	COG2508	Transcriptional regulator
H1Q60_RS08355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1Q60_RS08365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1Q60_RS08380	COG4894	glucomannan catabolic process
H1Q60_RS08385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H1Q60_RS08390	COG0500	methyltransferase
H1Q60_RS08395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1Q60_RS08415	COG0753	catalase activity
H1Q60_RS08415	COG0693	protein deglycase activity
H1Q60_RS08420	COG2851	Citrate transporter
H1Q60_RS08425	COG2273	Hydrolase Family 16
H1Q60_RS08440	COG0513	Belongs to the DEAD box helicase family
H1Q60_RS08540	COG0697	spore germination
H1Q60_RS08545	COG0589	response to stress
H1Q60_RS08555	COG0494	nUDIX hydrolase
H1Q60_RS08560	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
H1Q60_RS08565	COG3507	Belongs to the glycosyl hydrolase 43 family
H1Q60_RS08590	COG0010	Belongs to the arginase family
H1Q60_RS08600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H1Q60_RS08605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1Q60_RS08615	COG2390	Transcriptional regulator
H1Q60_RS08645	COG1131	(ABC) transporter
H1Q60_RS08655	COG0561	phosphatase activity
H1Q60_RS08685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1Q60_RS08690	COG5294	Protein conserved in bacteria
H1Q60_RS08695	COG0577	efflux transmembrane transporter activity
H1Q60_RS08700	COG1136	(ABC) transporter
H1Q60_RS08705	COG2205	protein histidine kinase activity
H1Q60_RS08710	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS08725	COG1082	Xylose isomerase domain protein TIM barrel
H1Q60_RS08735	COG2814	Major facilitator Superfamily
H1Q60_RS08765	COG1349	DNA-binding transcription factor activity
H1Q60_RS08770	COG0667	Aldo Keto reductase
H1Q60_RS08775	COG2814	Major facilitator Superfamily
H1Q60_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS08790	COG2197	response regulator
H1Q60_RS08795	COG4585	Histidine kinase
H1Q60_RS08800	COG3239	Fatty acid desaturase
H1Q60_RS08805	COG1309	transcriptional regulator
H1Q60_RS08815	COG1476	TRANSCRIPTIONal
H1Q60_RS08845	COG1012	belongs to the aldehyde dehydrogenase family
H1Q60_RS08860	COG0640	Transcriptional regulator
H1Q60_RS08865	COG2814	Major facilitator Superfamily
H1Q60_RS08870	COG1714	RDD family
H1Q60_RS08880	COG0450	alkyl hydroperoxide reductase
H1Q60_RS08885	COG3634	alkyl hydroperoxide reductase activity
H1Q60_RS08890	COG3177	Filamentation induced by cAMP protein fic
H1Q60_RS08895	COG1113	amino acid transport
H1Q60_RS08905	COG2080	2 iron, 2 sulfur cluster binding
H1Q60_RS08920	COG2068	MobA-Related Protein
H1Q60_RS08925	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H1Q60_RS08945	COG1192	Involved in chromosome partitioning
H1Q60_RS08985	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
H1Q60_RS08990	COG0667	Aldo Keto reductase
H1Q60_RS08995	COG0456	acetyltransferase
H1Q60_RS09000	COG0457	Tetratricopeptide repeat
H1Q60_RS09005	COG0010	Belongs to the arginase family
H1Q60_RS09010	COG0833	amino acid
H1Q60_RS09015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1Q60_RS09020	COG5658	integral membrane protein
H1Q60_RS09025	COG0640	Transcriptional regulator
H1Q60_RS09030	COG3829	transcription factor binding
H1Q60_RS09040	COG0488	(ABC) transporter
H1Q60_RS09055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1Q60_RS09060	COG5002	protein histidine kinase activity
H1Q60_RS09060	COG3850	Histidine kinase
H1Q60_RS09065	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS09075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Q60_RS09080	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H1Q60_RS09085	COG4853	Protein conserved in bacteria
H1Q60_RS09090	COG4863	YycH protein
H1Q60_RS09095	COG5002	protein histidine kinase activity
H1Q60_RS09100	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS09130	COG0346	lactoylglutathione lyase activity
H1Q60_RS09135	COG0305	Participates in initiation and elongation during chromosome replication
H1Q60_RS09150	COG3093	addiction module antidote protein HigA
H1Q60_RS09155	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H1Q60_RS09160	COG0297	glycogen (starch) synthase activity
H1Q60_RS09170	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H1Q60_RS09175	COG0438	transferase activity, transferring glycosyl groups
H1Q60_RS09185	COG2112	serine threonine protein kinase
H1Q60_RS09195	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H1Q60_RS09200	COG4241	membrane
H1Q60_RS09210	COG5577	PFAM Coat F domain
H1Q60_RS09215	COG1733	regulation of RNA biosynthetic process
H1Q60_RS09225	COG0697	spore germination
H1Q60_RS09230	COG1621	beta-fructofuranosidase activity
H1Q60_RS09235	COG1621	beta-fructofuranosidase activity
H1Q60_RS09245	COG2318	DinB family
H1Q60_RS09250	COG2211	Major facilitator Superfamily
H1Q60_RS09255	COG0697	spore germination
H1Q60_RS09265	COG0778	Nitroreductase
H1Q60_RS09270	COG1846	Transcriptional regulator
H1Q60_RS09275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1Q60_RS09280	COG1846	Transcriptional regulator
H1Q60_RS09285	COG2153	protein acetylation
H1Q60_RS09290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q60_RS09295	COG0697	spore germination
H1Q60_RS09330	COG1131	(ABC) transporter
H1Q60_RS09345	COG1331	Highly conserved protein containing a thioredoxin domain
H1Q60_RS09355	COG0457	Tetratricopeptide repeat
H1Q60_RS09370	COG0741	lytic transglycosylase activity
H1Q60_RS09370	COG0791	NLP P60 protein
H1Q60_RS09375	COG5644	endopeptidase inhibitor activity
H1Q60_RS09385	COG0433	COG0433 Predicted ATPase
H1Q60_RS09440	COG2946	Replication initiation factor
H1Q60_RS09445	COG1674	ftsk spoiiie
H1Q60_RS09470	COG1396	sequence-specific DNA binding
H1Q60_RS09475	COG2856	Zn peptidase
H1Q60_RS09480	COG1331	Highly conserved protein containing a thioredoxin domain
H1Q60_RS09485	COG1331	Highly conserved protein containing a thioredoxin domain
H1Q60_RS09490	COG1266	CAAX protease self-immunity
H1Q60_RS09495	COG0477	Major facilitator Superfamily
H1Q60_RS09495	COG2814	Major facilitator Superfamily
H1Q60_RS09500	COG0346	lactoylglutathione lyase activity
H1Q60_RS09505	COG1609	Transcriptional regulator
H1Q60_RS09515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1Q60_RS09520	COG2169	Transcriptional regulator
H1Q60_RS09530	COG0629	single-stranded DNA binding
H1Q60_RS09540	COG0012	GTP binding
H1Q60_RS09545	COG0243	molybdopterin cofactor binding
H1Q60_RS09550	COG4481	Protein conserved in bacteria
H1Q60_RS09555	COG3949	Membrane
H1Q60_RS09570	COG1475	DNA binding
H1Q60_RS09575	COG1192	Involved in chromosome partitioning
H1Q60_RS09600	COG1847	R3H domain protein
H1Q60_RS09605	COG0706	membrane insertase activity
H1Q60_RS09625	COG0592	DNA-directed DNA polymerase activity
H1Q60_RS09630	COG2501	S4 domain
H1Q60_RS09645	COG0187	DNA topoisomerase II activity
H1Q60_RS09650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H1Q60_RS09685	COG0516	GMP reductase activity
H1Q60_RS09685	COG0517	IMP dehydrogenase activity
H1Q60_RS09690	COG1686	Belongs to the peptidase S11 family
H1Q60_RS09710	COG1929	Belongs to the glycerate kinase type-1 family
H1Q60_RS09720	COG1428	Deoxynucleoside kinase
H1Q60_RS09725	COG1428	Deoxynucleoside kinase
H1Q60_RS09730	COG1388	LysM domain
H1Q60_RS09730	COG3858	chitin binding
H1Q60_RS09735	COG1335	isochorismatase
H1Q60_RS09740	COG0590	tRNA wobble adenosine to inosine editing
H1Q60_RS09750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1Q60_RS09755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H1Q60_RS09805	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
H1Q60_RS09810	COG3853	Toxic anion resistance protein (TelA)
H1Q60_RS09815	COG1982	Orn Lys Arg decarboxylase major
H1Q60_RS09825	COG3870	Protein conserved in bacteria
H1Q60_RS09830	COG1728	Protein conserved in bacteria
H1Q60_RS09835	COG0470	DNA polymerase III
H1Q60_RS09840	COG1774	PSP1 C-terminal conserved region
H1Q60_RS09850	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H1Q60_RS09860	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H1Q60_RS09865	COG2002	toxin-antitoxin pair type II binding
H1Q60_RS09870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1Q60_RS09870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1Q60_RS09875	COG0084	hydrolase, TatD family'
H1Q60_RS09880	COG3584	3D domain protein
H1Q60_RS09880	COG3583	domain protein
H1Q60_RS09885	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H1Q60_RS09890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1Q60_RS09900	COG4466	Protein conserved in bacteria
H1Q60_RS09915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H1Q60_RS09920	COG0251	oxidation-reduction process
H1Q60_RS09935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1Q60_RS09955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1Q60_RS09960	COG2002	toxin-antitoxin pair type II binding
H1Q60_RS09965	COG2244	polysaccharide biosynthetic process
H1Q60_RS09970	COG3956	TIGRFAM MazG family protein
H1Q60_RS09975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1Q60_RS09990	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1Q60_RS09995	COG1098	S1 RNA binding domain
H1Q60_RS10010	COG2208	phosphoserine phosphatase activity
H1Q60_RS10015	COG2304	oxidoreductase activity
H1Q60_RS10020	COG0515	serine threonine protein kinase
H1Q60_RS10025	COG0037	tRNA processing
H1Q60_RS10035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1Q60_RS10050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1Q60_RS10055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1Q60_RS10060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1Q60_RS10065	COG0512	Glutamine amidotransferase of anthranilate synthase
H1Q60_RS10070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1Q60_RS10075	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1Q60_RS10080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H1Q60_RS10085	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1Q60_RS10090	COG1396	sequence-specific DNA binding
H1Q60_RS10095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1Q60_RS10100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H1Q60_RS10180	COG4463	regulation of RNA biosynthetic process
H1Q60_RS10185	COG3880	PFAM UvrB UvrC protein
H1Q60_RS10195	COG0542	response to heat
H1Q60_RS10200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H1Q60_RS10205	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H1Q60_RS10210	COG4956	integral membrane protein (PIN domain superfamily)
H1Q60_RS10230	COG1045	serine acetyltransferase
H1Q60_RS10240	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H1Q60_RS10245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1Q60_RS10250	COG3688	RNA-binding protein containing a PIN domain
H1Q60_RS10255	COG1595	DNA-templated transcription, initiation
H1Q60_RS10265	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H1Q60_RS10270	COG0250	Participates in transcription elongation, termination and antitermination
H1Q60_RS10295	COG2813	Specifically methylates the guanine in position
H1Q60_RS10310	COG1358	cellular component organization or biogenesis
H1Q60_RS10335	COG0596	Alpha beta hydrolase
H1Q60_RS10445	COG0201	protein transport
H1Q60_RS10455	COG0024	Methionine aminopeptidase
H1Q60_RS10465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H1Q60_RS10490	COG1122	ATPase activity
H1Q60_RS10495	COG1122	ATPase activity
H1Q60_RS10500	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H1Q60_RS10520	COG2226	methyltransferase
H1Q60_RS10525	COG2318	DinB family
H1Q60_RS10535	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Q60_RS10540	COG0489	protein tyrosine kinase activity
H1Q60_RS10550	COG2194	sulfuric ester hydrolase activity
H1Q60_RS10555	COG0726	polysaccharide deacetylase
H1Q60_RS10615	COG0738	Major facilitator superfamily
H1Q60_RS10620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1Q60_RS10635	COG0659	secondary active sulfate transmembrane transporter activity
H1Q60_RS10640	COG0385	Bile acid
H1Q60_RS10645	COG2819	hydrolase of the alpha beta superfamily
H1Q60_RS10650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q60_RS10655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q60_RS10660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1Q60_RS10665	COG2207	Transcriptional regulator
H1Q60_RS10665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1Q60_RS10670	COG3876	Protein conserved in bacteria
H1Q60_RS10675	COG1472	Belongs to the glycosyl hydrolase 3 family
H1Q60_RS10680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1Q60_RS10685	COG1263	PTS System
H1Q60_RS10685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Q60_RS10695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Q60_RS10700	COG1683	Conserved Protein
H1Q60_RS10730	COG1595	DNA-templated transcription, initiation
H1Q60_RS10735	COG5662	AntiSigma factor
H1Q60_RS10740	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H1Q60_RS10745	COG4856	YbbR-like protein
H1Q60_RS10785	COG1346	cytolysis
H1Q60_RS10790	COG1380	Effector of murein hydrolase LrgA
H1Q60_RS10795	COG1846	Transcriptional regulator
H1Q60_RS10800	COG1113	amino acid transport
H1Q60_RS10805	COG1011	Hydrolase
H1Q60_RS10810	COG4585	Histidine kinase
H1Q60_RS10815	COG2197	response regulator
H1Q60_RS10820	COG1131	(ABC) transporter
H1Q60_RS10860	COG0531	amino acid
H1Q60_RS10885	COG0584	glycerophosphoryl diester phosphodiesterase
H1Q60_RS10890	COG2271	Major facilitator Superfamily
H1Q60_RS10900	COG2368	4-hydroxyphenylacetate
H1Q60_RS10910	COG3409	Peptidoglycan-binding domain 1 protein
H1Q60_RS10925	COG0371	Dehydrogenase
H1Q60_RS10935	COG1183	phosphatidylcholine synthase activity
H1Q60_RS10940	COG0586	Pfam SNARE associated Golgi protein
H1Q60_RS10945	COG0688	phosphatidylethanolamine metabolic process
H1Q60_RS10960	COG1301	dicarboxylic acid transport
H1Q60_RS10965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1Q60_RS10970	COG0833	amino acid
H1Q60_RS10975	COG2040	homocysteine
H1Q60_RS10980	COG1115	amino acid carrier protein
H1Q60_RS10985	COG2066	Belongs to the glutaminase family
H1Q60_RS10990	COG4191	Histidine kinase
H1Q60_RS10995	COG0784	Response regulator, receiver
H1Q60_RS11000	COG3173	Aminoglycoside phosphotransferase
H1Q60_RS11015	COG3773	Cell wall hydrolase
H1Q60_RS11020	COG3540	Alkaline phosphatase
H1Q60_RS11025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1Q60_RS11030	COG0805	protein transport
H1Q60_RS11040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1Q60_RS11045	COG0477	Major facilitator Superfamily
H1Q60_RS11050	COG1309	transcriptional regulator
H1Q60_RS11055	COG0252	asparaginase activity
H1Q60_RS11060	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H1Q60_RS11065	COG1405	negative regulation of cell septum assembly
H1Q60_RS11065	COG3012	SEC-C Motif Domain Protein
H1Q60_RS11070	COG0667	Aldo Keto reductase
H1Q60_RS11080	COG1595	DNA-templated transcription, initiation
H1Q60_RS11085	COG1595	DNA-templated transcription, initiation
H1Q60_RS11090	COG1876	peptidase activity
H1Q60_RS11095	COG0457	Tetratricopeptide repeat
H1Q60_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS11125	COG0366	Alpha amylase catalytic
H1Q60_RS11130	COG0803	Belongs to the bacterial solute-binding protein 9 family
H1Q60_RS11135	COG1121	(ABC) transporter
H1Q60_RS11140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Q60_RS11145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Q60_RS11150	COG2310	stress, protein
H1Q60_RS11155	COG2310	stress, protein
H1Q60_RS11160	COG2310	stress, protein
H1Q60_RS11165	COG0861	Integral membrane protein TerC family
H1Q60_RS11175	COG3853	Toxic anion resistance protein (TelA)
H1Q60_RS11180	COG0477	Major facilitator Superfamily
H1Q60_RS11185	COG4175	Glycine betaine
H1Q60_RS11185	COG0517	IMP dehydrogenase activity
H1Q60_RS11190	COG4176	ABC-type proline glycine betaine transport system permease component
H1Q60_RS11195	COG2113	Glycine betaine
H1Q60_RS11200	COG1473	amidohydrolase
H1Q60_RS11205	COG1288	antiporter activity
H1Q60_RS11285	COG2814	Major facilitator Superfamily
H1Q60_RS11290	COG1846	Transcriptional regulator
H1Q60_RS11295	COG1280	lysine exporter protein (LysE YggA)
H1Q60_RS11300	COG3403	YqcI/YcgG family
H1Q60_RS11305	COG1113	amino acid transport
H1Q60_RS11310	COG3665	Urea carboxylase-associated protein
H1Q60_RS11325	COG1660	Displays ATPase and GTPase activities
H1Q60_RS11335	COG2271	Major facilitator Superfamily
H1Q60_RS11340	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H1Q60_RS11345	COG3458	cephalosporin-C deacetylase activity
H1Q60_RS11350	COG3541	Predicted nucleotidyltransferase
H1Q60_RS11355	COG0506	proline dehydrogenase activity
H1Q60_RS11360	COG1012	belongs to the aldehyde dehydrogenase family
H1Q60_RS11365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1Q60_RS11370	COG2508	Transcriptional regulator
H1Q60_RS11380	COG1587	Uroporphyrinogen-III synthase
H1Q60_RS11380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1Q60_RS11385	COG2146	nitrite reductase [NAD(P)H] activity
H1Q60_RS11390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1Q60_RS11395	COG0243	molybdopterin cofactor binding
H1Q60_RS11400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1Q60_RS11405	COG2223	nitrite transmembrane transporter activity
H1Q60_RS11410	COG0523	cobalamin synthesis protein
H1Q60_RS11415	COG1063	alcohol dehydrogenase
H1Q60_RS11420	COG1714	RDD family
H1Q60_RS11440	COG3209	COG3209 Rhs family protein
H1Q60_RS11445	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1Q60_RS11450	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H1Q60_RS11455	COG1733	regulation of RNA biosynthetic process
H1Q60_RS11460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS11465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS11470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS11475	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1Q60_RS11490	COG2364	Membrane
H1Q60_RS11495	COG1126	abc transporter atp-binding protein
H1Q60_RS11500	COG0765	amino acid transport
H1Q60_RS11505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q60_RS11510	COG0583	DNA-binding transcription factor activity
H1Q60_RS11515	COG0163	prenyltransferase activity
H1Q60_RS11520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H1Q60_RS11535	COG3104	oligopeptide transport
H1Q60_RS11540	COG5434	Belongs to the glycosyl hydrolase 28 family
H1Q60_RS11550	COG0697	spore germination
H1Q60_RS11560	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1Q60_RS11565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Q60_RS11570	COG0456	acetyltransferase
H1Q60_RS11575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q60_RS11580	COG0765	amino acid transport
H1Q60_RS11585	COG1126	abc transporter atp-binding protein
H1Q60_RS11590	COG1473	amidohydrolase
H1Q60_RS11595	COG2079	MmgE PrpD family protein
H1Q60_RS11600	COG1136	(ABC) transporter
H1Q60_RS11605	COG0577	efflux transmembrane transporter activity
H1Q60_RS11610	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS11615	COG5002	protein histidine kinase activity
H1Q60_RS11615	COG3850	Histidine kinase
H1Q60_RS11620	COG0457	Tetratricopeptide repeat
H1Q60_RS11635	COG0527	aspartate kinase activity
H1Q60_RS11640	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q60_RS11645	COG4605	iron ion homeostasis
H1Q60_RS11650	COG4604	ABC transporter, ATP-binding protein
H1Q60_RS11655	COG4607	ABC-type enterochelin transport system periplasmic component
H1Q60_RS11660	COG2814	Major facilitator Superfamily
H1Q60_RS11665	COG1309	transcriptional regulator
H1Q60_RS11670	COG0778	Nitroreductase
H1Q60_RS11675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1Q60_RS11680	COG0640	Transcriptional regulator
H1Q60_RS11685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q60_RS11690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1Q60_RS11695	COG1012	belongs to the aldehyde dehydrogenase family
H1Q60_RS11700	COG4975	Glucose uptake
H1Q60_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS11710	COG4549	nuclear export factor GLE1
H1Q60_RS11715	COG1276	copper resistance
H1Q60_RS11715	COG2372	response to copper ion
H1Q60_RS11720	COG1349	DNA-binding transcription factor activity
H1Q60_RS11730	COG2213	PTS system mannitol-specific
H1Q60_RS11735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q60_RS11750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H1Q60_RS11760	COG0561	phosphatase activity
H1Q60_RS11770	COG1914	H( )-stimulated, divalent metal cation uptake system
H1Q60_RS11780	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H1Q60_RS11785	COG1984	allophanate hydrolase subunit 2
H1Q60_RS11790	COG1414	Transcriptional regulator
H1Q60_RS11795	COG2755	lipolytic protein G-D-S-L family
H1Q60_RS11805	COG2329	Antibiotic biosynthesis monooxygenase
H1Q60_RS11810	COG0768	penicillin binding
H1Q60_RS11815	COG4989	oxidoreductase activity
H1Q60_RS11820	COG3711	transcriptional antiterminator
H1Q60_RS11825	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q60_RS11830	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS11835	COG1917	Cupin 2, conserved barrel domain protein
H1Q60_RS11840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Q60_RS11845	COG3871	stress protein (general stress protein 26)
H1Q60_RS11855	COG2814	Major facilitator Superfamily
H1Q60_RS11860	COG1522	sequence-specific DNA binding
H1Q60_RS11865	COG0551	DNA topoisomerase type I activity
H1Q60_RS11865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1Q60_RS11870	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H1Q60_RS11880	COG5298	Protein conserved in bacteria
H1Q60_RS11885	COG1215	transferase activity, transferring glycosyl groups
H1Q60_RS11895	COG0531	amino acid
H1Q60_RS11900	COG0494	nUDIX hydrolase
H1Q60_RS11905	COG0028	Belongs to the TPP enzyme family
H1Q60_RS11915	COG3409	Peptidoglycan-binding domain 1 protein
H1Q60_RS11915	COG5632	N-Acetylmuramoyl-L-alanine amidase
H1Q60_RS11915	COG1388	LysM domain
H1Q60_RS11930	COG0457	Tetratricopeptide repeat
H1Q60_RS11950	COG1914	H( )-stimulated, divalent metal cation uptake system
H1Q60_RS11965	COG4876	unkown
H1Q60_RS11975	COG2076	Multidrug Resistance protein
H1Q60_RS11980	COG2217	Heavy metal translocating P-type atpase
H1Q60_RS11985	COG3729	General stress protein
H1Q60_RS11990	COG0662	Cupin 2, conserved barrel domain protein
H1Q60_RS11995	COG2329	Antibiotic biosynthesis monooxygenase
H1Q60_RS12000	COG3546	catalase activity
H1Q60_RS12005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q60_RS12010	COG3290	protein histidine kinase activity
H1Q60_RS12015	COG4565	transcriptional regulatory protein
H1Q60_RS12020	COG1301	dicarboxylic acid transport
H1Q60_RS12025	COG0628	permease
H1Q60_RS12030	COG1131	(ABC) transporter
H1Q60_RS12035	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H1Q60_RS12045	COG1960	acyl-CoA dehydrogenase activity
H1Q60_RS12060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H1Q60_RS12065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q60_RS12075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1Q60_RS12080	COG0513	Belongs to the DEAD box helicase family
H1Q60_RS12085	COG3402	PFAM membrane-flanked domain
H1Q60_RS12090	COG3428	Bacterial PH domain
H1Q60_RS12095	COG0705	Rhomboid family
H1Q60_RS12105	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1Q60_RS12110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1Q60_RS12115	COG0864	Transcriptional regulator
H1Q60_RS12120	COG2337	Toxic component of a toxin-antitoxin (TA) module
H1Q60_RS12125	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q60_RS12130	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q60_RS12135	COG2172	sigma factor antagonist activity
H1Q60_RS12140	COG2208	phosphoserine phosphatase activity
H1Q60_RS12145	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q60_RS12155	COG1191	sigma factor activity
H1Q60_RS12160	COG2208	phosphoserine phosphatase activity
H1Q60_RS12165	COG2183	response to ionizing radiation
H1Q60_RS12230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1Q60_RS12235	COG0477	Major facilitator Superfamily
H1Q60_RS12245	COG2030	dehydratase
H1Q60_RS12260	COG1959	2 iron, 2 sulfur cluster binding
H1Q60_RS12265	COG2910	NAD(P)H-binding
H1Q60_RS12275	COG1278	Cold shock
H1Q60_RS12280	COG1329	Transcriptional regulator
H1Q60_RS12285	COG1937	Protein conserved in bacteria
H1Q60_RS12290	COG2210	Belongs to the sulfur carrier protein TusA family
H1Q60_RS12300	COG0425	Belongs to the sulfur carrier protein TusA family
H1Q60_RS12300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1Q60_RS12305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1Q60_RS12305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q60_RS12310	COG0425	Belongs to the sulfur carrier protein TusA family
H1Q60_RS12315	COG0730	response to heat
H1Q60_RS12320	COG1794	racemase activity, acting on amino acids and derivatives
H1Q60_RS12335	COG3621	Patatin-like phospholipase
H1Q60_RS12345	COG0662	Cupin 2, conserved barrel domain protein
H1Q60_RS12360	COG3328	transposase activity
H1Q60_RS12365	COG0277	FAD linked oxidase domain protein
H1Q60_RS12390	COG0662	Cupin 2, conserved barrel domain protein
H1Q60_RS12395	COG2318	DinB family
H1Q60_RS12400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1Q60_RS12425	COG1064	alcohol dehydrogenase
H1Q60_RS12430	COG0789	Transcriptional regulator
H1Q60_RS12440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q60_RS12455	COG2814	Major facilitator Superfamily
H1Q60_RS12460	COG1309	transcriptional regulator
H1Q60_RS12465	COG0697	spore germination
H1Q60_RS12470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q60_RS12475	COG5577	PFAM Coat F domain
H1Q60_RS12485	COG1063	alcohol dehydrogenase
H1Q60_RS12490	COG5577	PFAM Coat F domain
H1Q60_RS12500	COG4585	Histidine kinase
H1Q60_RS12505	COG2197	response regulator
H1Q60_RS12510	COG2409	Drug exporters of the RND superfamily
H1Q60_RS12515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H1Q60_RS12525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Q60_RS12530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1Q60_RS12540	COG2814	Major facilitator Superfamily
H1Q60_RS12545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1Q60_RS12555	COG0730	response to heat
H1Q60_RS12560	COG0456	acetyltransferase
H1Q60_RS12565	COG4978	Transcriptional regulator
H1Q60_RS12565	COG0789	Transcriptional regulator
H1Q60_RS12570	COG0697	spore germination
H1Q60_RS12575	COG1051	belongs to the nudix hydrolase family
H1Q60_RS12580	COG2226	methyltransferase
H1Q60_RS12585	COG0473	3-isopropylmalate dehydrogenase activity
H1Q60_RS12590	COG1802	Transcriptional regulator
H1Q60_RS12595	COG1819	glycosyl
H1Q60_RS12610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1Q60_RS12620	COG1388	LysM domain
H1Q60_RS12625	COG2814	Major facilitator Superfamily
H1Q60_RS12630	COG2188	Transcriptional regulator
H1Q60_RS12635	COG2186	Transcriptional regulator
H1Q60_RS12640	COG2807	transmembrane transport
H1Q60_RS12645	COG2076	Multidrug Resistance protein
H1Q60_RS12650	COG2076	Multidrug Resistance protein
H1Q60_RS12655	COG1309	transcriptional regulator
H1Q60_RS12660	COG0531	amino acid
H1Q60_RS12670	COG3832	glyoxalase III activity
H1Q60_RS12675	COG0604	alcohol dehydrogenase
H1Q60_RS12680	COG2814	Major facilitator Superfamily
H1Q60_RS12720	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1Q60_RS12725	COG0802	atpase or kinase
H1Q60_RS12730	COG1214	PFAM Peptidase M22, glycoprotease
H1Q60_RS12735	COG0456	acetyltransferase
H1Q60_RS12740	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H1Q60_RS12745	COG0488	(ABC) transporter
H1Q60_RS12760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1Q60_RS12765	COG0805	protein transport
H1Q60_RS12775	COG1266	CAAX protease self-immunity
H1Q60_RS12790	COG0156	8-amino-7-oxononanoate synthase activity
H1Q60_RS12810	COG3403	YqcI/YcgG family
H1Q60_RS12825	COG2814	Major facilitator Superfamily
H1Q60_RS12830	COG0457	Tetratricopeptide repeat
H1Q60_RS12835	COG1063	alcohol dehydrogenase
H1Q60_RS12840	COG2211	Major facilitator Superfamily
H1Q60_RS12845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Q60_RS12855	COG1842	Phage shock protein A
H1Q60_RS12860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1Q60_RS12865	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1Q60_RS12870	COG4260	virion core protein, lumpy skin disease virus
H1Q60_RS12875	COG2755	lipolytic protein G-D-S-L family
H1Q60_RS12875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H1Q60_RS12885	COG1595	DNA-templated transcription, initiation
H1Q60_RS12890	COG1063	alcohol dehydrogenase
H1Q60_RS12895	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1Q60_RS12900	COG0823	Involved in the tonB-independent uptake of proteins
H1Q60_RS12915	COG2132	Multicopper oxidase
H1Q60_RS12920	COG1113	amino acid transport
H1Q60_RS12925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H1Q60_RS12930	COG0714	Associated with various cellular activities
H1Q60_RS12935	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
H1Q60_RS12940	COG1305	Transglutaminase-like
H1Q60_RS12950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H1Q60_RS12965	COG2211	Major facilitator Superfamily
H1Q60_RS12980	COG2252	PERMEase
H1Q60_RS12985	COG3064	Membrane
H1Q60_RS13005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H1Q60_RS13010	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1Q60_RS13015	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1Q60_RS13020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H1Q60_RS13025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1Q60_RS13040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H1Q60_RS13050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1Q60_RS13055	COG0138	bifunctional purine biosynthesis protein purh
H1Q60_RS13060	COG0151	Belongs to the GarS family
H1Q60_RS13070	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1Q60_RS13075	COG1470	cell adhesion involved in biofilm formation
H1Q60_RS13080	COG4496	protein, YerC YecD
H1Q60_RS13085	COG0069	glutamate synthase activity
H1Q60_RS13095	COG0210	DNA helicase
H1Q60_RS13105	COG4851	CamS sex pheromone cAM373 precursor
H1Q60_RS13110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1Q60_RS13115	COG1285	pathogenesis
H1Q60_RS13120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1Q60_RS13140	COG1309	transcriptional regulator
H1Q60_RS13145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Q60_RS13150	COG1597	lipid kinase activity
H1Q60_RS13155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H1Q60_RS13170	COG0367	asparagine synthase
H1Q60_RS13205	COG1136	(ABC) transporter
H1Q60_RS13215	COG1131	(ABC) transporter
H1Q60_RS13255	COG5444	nuclease activity
H1Q60_RS13285	COG3546	catalase activity
H1Q60_RS13290	COG0454	-acetyltransferase
H1Q60_RS13300	COG2323	membrane
H1Q60_RS13305	COG2329	Antibiotic biosynthesis monooxygenase
H1Q60_RS13310	COG0346	lactoylglutathione lyase activity
H1Q60_RS13315	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q60_RS13320	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1Q60_RS13325	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1Q60_RS13330	COG4208	sulfate ABC transporter
H1Q60_RS13340	COG5583	Uncharacterized small protein (DUF2292)
H1Q60_RS13345	COG0196	riboflavin kinase activity
H1Q60_RS13350	COG0670	Belongs to the BI1 family
H1Q60_RS13355	COG1846	Transcriptional regulator
H1Q60_RS13360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1Q60_RS13370	COG2124	cytochrome p450
H1Q60_RS13370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1Q60_RS13385	COG1131	(ABC) transporter
H1Q60_RS13395	COG1368	sulfuric ester hydrolase activity
H1Q60_RS13400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1Q60_RS13405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q60_RS13410	COG1442	glycosyl transferase family 8
H1Q60_RS13415	COG1216	Glycosyl transferase, family 2
H1Q60_RS13425	COG2223	nitrite transmembrane transporter activity
H1Q60_RS13430	COG0531	amino acid
H1Q60_RS13435	COG1012	belongs to the aldehyde dehydrogenase family
H1Q60_RS13440	COG0840	transmembrane signaling receptor activity
H1Q60_RS13445	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS13450	COG0463	Glycosyl transferase, family 2
H1Q60_RS13450	COG0457	Tetratricopeptide repeat
H1Q60_RS13455	COG0488	(ABC) transporter
H1Q60_RS13460	COG0789	Transcriptional regulator
H1Q60_RS13465	COG2814	Major facilitator Superfamily
H1Q60_RS13470	COG0488	(ABC) transporter
H1Q60_RS13475	COG0513	Belongs to the DEAD box helicase family
H1Q60_RS13480	COG0456	acetyltransferase
H1Q60_RS13485	COG2130	NADP-dependent
H1Q60_RS13500	COG3866	Pectate lyase
H1Q60_RS13505	COG0471	metal ion transport
H1Q60_RS13520	COG3290	protein histidine kinase activity
H1Q60_RS13525	COG4565	transcriptional regulatory protein
H1Q60_RS13530	COG3181	Tripartite tricarboxylate transporter family receptor
H1Q60_RS13535	COG2851	Citrate transporter
H1Q60_RS13540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q60_RS13545	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H1Q60_RS13555	COG2258	MOSC domain
H1Q60_RS13575	COG0024	Methionine aminopeptidase
H1Q60_RS13580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Q60_RS13580	COG1263	PTS System
H1Q60_RS13590	COG1368	sulfuric ester hydrolase activity
H1Q60_RS13600	COG0071	Belongs to the small heat shock protein (HSP20) family
H1Q60_RS13615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Q60_RS13615	COG1263	PTS System
H1Q60_RS13620	COG0366	Alpha amylase catalytic
H1Q60_RS13625	COG2188	Transcriptional regulator
H1Q60_RS13630	COG0778	Nitroreductase
H1Q60_RS13645	COG0737	Belongs to the 5'-nucleotidase family
H1Q60_RS13650	COG0693	protein deglycase activity
H1Q60_RS13655	COG1609	Transcriptional regulator
H1Q60_RS13670	COG2814	Major facilitator Superfamily
H1Q60_RS13680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1Q60_RS13685	COG4980	gas vesicle protein
H1Q60_RS13690	COG1295	ribonuclease BN
H1Q60_RS13700	COG0477	Major facilitator Superfamily
H1Q60_RS13705	COG0387	Pfam Sodium calcium exchanger
H1Q60_RS13715	COG0668	transmembrane transport
H1Q60_RS13720	COG0535	radical SAM domain protein
H1Q60_RS13730	COG0726	polysaccharide deacetylase
H1Q60_RS13735	COG2084	Dehydrogenase
H1Q60_RS13745	COG0598	Magnesium transport protein CorA
H1Q60_RS13750	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H1Q60_RS13755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H1Q60_RS13770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1Q60_RS13775	COG4637	Psort location Cytoplasmic, score
H1Q60_RS13780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1Q60_RS13785	COG0022	dehydrogenase e1 component
H1Q60_RS13790	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q60_RS13795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1Q60_RS13800	COG3284	Transcriptional regulator
H1Q60_RS13810	COG1486	melibiose metabolic process
H1Q60_RS13815	COG1737	Transcriptional regulator
H1Q60_RS13820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Q60_RS13820	COG1263	PTS System
H1Q60_RS13825	COG1132	(ABC) transporter
H1Q60_RS13830	COG1132	(ABC) transporter
H1Q60_RS13835	COG2259	Doxx family
H1Q60_RS13840	COG2514	catechol 2,3-dioxygenase activity
H1Q60_RS13850	COG1695	Transcriptional regulator
H1Q60_RS13855	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1Q60_RS13860	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
H1Q60_RS13865	COG3848	Pyruvate phosphate dikinase
H1Q60_RS13865	COG0574	Belongs to the PEP-utilizing enzyme family
H1Q60_RS13870	COG2732	(Barnase) inhibitor
H1Q60_RS13875	COG2318	DinB family
H1Q60_RS13880	COG2814	Major facilitator Superfamily
H1Q60_RS13885	COG1846	Transcriptional regulator
H1Q60_RS13890	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H1Q60_RS13890	COG0392	lysyltransferase activity
H1Q60_RS13895	COG0384	phenazine biosynthesis protein PhzF
H1Q60_RS13900	COG0778	Nitroreductase
H1Q60_RS13915	COG1090	epimerase
H1Q60_RS13930	COG2814	Major facilitator Superfamily
H1Q60_RS13940	COG3591	Belongs to the peptidase S1B family
H1Q60_RS13955	COG3103	Sh3 type 3 domain protein
H1Q60_RS13960	COG5658	integral membrane protein
H1Q60_RS13965	COG0596	Alpha beta hydrolase
H1Q60_RS13970	COG0463	Glycosyl transferase, family 2
H1Q60_RS13975	COG4485	Bacterial membrane protein, YfhO
H1Q60_RS13980	COG1988	membrane-bound metal-dependent
H1Q60_RS13985	COG0582	viral genome integration into host DNA
H1Q60_RS14025	COG3645	SOS response
H1Q60_RS14025	COG3646	Phage regulatory protein
H1Q60_RS14050	COG0305	Participates in initiation and elongation during chromosome replication
H1Q60_RS14080	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1Q60_RS14085	COG0582	viral genome integration into host DNA
H1Q60_RS14090	COG1674	ftsk spoiiie
H1Q60_RS14090	COG4980	gas vesicle protein
H1Q60_RS14125	COG0740	serine-type endopeptidase activity
H1Q60_RS14165	COG3953	SLT domain
H1Q60_RS14165	COG5280	Phage tail tape measure protein TP901
H1Q60_RS14230	COG0457	Tetratricopeptide repeat
H1Q60_RS14245	COG1194	a g-specific adenine glycosylase
H1Q60_RS14255	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS14275	COG1132	(ABC) transporter
H1Q60_RS14280	COG4129	membrane
H1Q60_RS14290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1Q60_RS14295	COG0735	belongs to the Fur family
H1Q60_RS14435	COG5577	PFAM Coat F domain
H1Q60_RS14440	COG3340	Belongs to the peptidase S51 family
H1Q60_RS14450	COG0277	FAD linked oxidase domain protein
H1Q60_RS14460	COG0747	negative chemotaxis
H1Q60_RS14465	COG0601	transmembrane transport
H1Q60_RS14470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q60_RS14475	COG0444	Belongs to the ABC transporter superfamily
H1Q60_RS14480	COG4608	Belongs to the ABC transporter superfamily
H1Q60_RS14485	COG0753	catalase activity
H1Q60_RS14495	COG1116	anion transmembrane transporter activity
H1Q60_RS14500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Q60_RS14505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q60_RS14530	COG1476	TRANSCRIPTIONal
H1Q60_RS14540	COG3382	B3 4 domain protein
H1Q60_RS14545	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1Q60_RS14555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1Q60_RS14560	COG0789	Transcriptional regulator
H1Q60_RS14565	COG1664	Polymer-forming cytoskeletal
H1Q60_RS14570	COG1664	Polymer-forming cytoskeletal
H1Q60_RS14575	COG2766	serine protein kinase
H1Q60_RS14585	COG1846	Transcriptional regulator
H1Q60_RS14590	COG1566	PFAM secretion protein HlyD family protein
H1Q60_RS14595	COG2814	Major facilitator Superfamily
H1Q60_RS14600	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1Q60_RS14615	COG1725	Transcriptional regulator
H1Q60_RS14620	COG1131	(ABC) transporter
H1Q60_RS14625	COG1131	(ABC) transporter
H1Q60_RS14630	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H1Q60_RS14635	COG1278	Cold shock
H1Q60_RS14640	COG1464	Belongs to the NlpA lipoprotein family
H1Q60_RS14645	COG3706	GGDEF domain
H1Q60_RS14650	COG1823	symporter activity
H1Q60_RS14670	COG5577	PFAM Coat F domain
H1Q60_RS14675	COG4085	toxin activity
H1Q60_RS14675	COG0737	Belongs to the 5'-nucleotidase family
H1Q60_RS14675	COG1525	nuclease
H1Q60_RS14680	COG3764	Sortase (surface protein transpeptidase)
H1Q60_RS14685	COG0564	pseudouridine synthase activity
H1Q60_RS14695	COG0517	IMP dehydrogenase activity
H1Q60_RS14700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1Q60_RS14705	COG3153	acetyltransferase
H1Q60_RS14705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1Q60_RS14710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H1Q60_RS14715	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H1Q60_RS14720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H1Q60_RS14730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H1Q60_RS14735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1Q60_RS14740	COG4585	Histidine kinase
H1Q60_RS14740	COG2203	Gaf domain
H1Q60_RS14745	COG2197	response regulator
H1Q60_RS14750	COG0431	NADPH-dependent FMN reductase
H1Q60_RS14765	COG0791	NLP P60 protein
H1Q60_RS14765	COG1388	LysM domain
H1Q60_RS14770	COG1959	2 iron, 2 sulfur cluster binding
H1Q60_RS14775	COG0668	transmembrane transport
H1Q60_RS14780	COG2719	SpoVR family
H1Q60_RS14785	COG1785	Belongs to the alkaline phosphatase family
H1Q60_RS14790	COG1388	LysM domain
H1Q60_RS14790	COG0791	NLP P60 protein
H1Q60_RS14795	COG0583	DNA-binding transcription factor activity
H1Q60_RS14800	COG0372	Belongs to the citrate synthase family
H1Q60_RS14805	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS14810	COG0531	amino acid
H1Q60_RS14815	COG0733	neurotransmitter:sodium symporter activity
H1Q60_RS14830	COG1595	DNA-templated transcription, initiation
H1Q60_RS14835	COG0204	Acyl-transferase
H1Q60_RS14840	COG1253	flavin adenine dinucleotide binding
H1Q60_RS14845	COG0789	Transcriptional regulator
H1Q60_RS14850	COG0436	Aminotransferase
H1Q60_RS14855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1Q60_RS14860	COG1253	flavin adenine dinucleotide binding
H1Q60_RS14865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H1Q60_RS14870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H1Q60_RS14875	COG0584	glycerophosphoryl diester phosphodiesterase
H1Q60_RS14885	COG0668	transmembrane transport
H1Q60_RS14890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1Q60_RS14895	COG0726	polysaccharide deacetylase
H1Q60_RS14900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1Q60_RS14905	COG3226	Transcriptional regulator
H1Q60_RS14915	COG0589	response to stress
H1Q60_RS14920	COG1132	(ABC) transporter
H1Q60_RS14925	COG1132	(ABC) transporter
H1Q60_RS14930	COG0702	epimerase
H1Q60_RS14945	COG0189	ligase activity
H1Q60_RS14950	COG0189	ligase activity
H1Q60_RS14965	COG4335	DNA alkylation repair
H1Q60_RS14970	COG0561	phosphatase activity
H1Q60_RS14975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1Q60_RS14985	COG0475	glutathione-regulated potassium exporter activity
H1Q60_RS14990	COG0490	domain, Protein
H1Q60_RS15000	COG1024	Enoyl-CoA hydratase
H1Q60_RS15010	COG4152	abc transporter atp-binding protein
H1Q60_RS15015	COG1668	transmembrane transport
H1Q60_RS15020	COG0420	3'-5' exonuclease activity
H1Q60_RS15025	COG4717	serine-type aminopeptidase activity
H1Q60_RS15040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1Q60_RS15075	COG4980	gas vesicle protein
H1Q60_RS15090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H1Q60_RS15095	COG0537	adenosine 5'-monophosphoramidase activity
H1Q60_RS15100	COG1131	(ABC) transporter
H1Q60_RS15105	COG4473	ABC transporter
H1Q60_RS15115	COG1473	amidohydrolase
H1Q60_RS15120	COG3069	C4-dicarboxylate transmembrane transporter activity
H1Q60_RS15125	COG2329	Antibiotic biosynthesis monooxygenase
H1Q60_RS15130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1Q60_RS15150	COG1309	transcriptional regulator
H1Q60_RS15155	COG1511	domain protein
H1Q60_RS15160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H1Q60_RS15170	COG1363	Peptidase, m42
H1Q60_RS15175	COG1301	dicarboxylic acid transport
H1Q60_RS15185	COG1234	tRNA 3'-trailer cleavage
H1Q60_RS15190	COG0095	Lipoate-protein ligase
H1Q60_RS15195	COG0702	epimerase
H1Q60_RS15200	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q60_RS15210	COG0501	Belongs to the peptidase M48B family
H1Q60_RS15215	COG1404	Belongs to the peptidase S8 family
H1Q60_RS15220	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H1Q60_RS15225	COG0406	alpha-ribazole phosphatase activity
H1Q60_RS15230	COG0183	Belongs to the thiolase family
H1Q60_RS15235	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q60_RS15240	COG1268	BioY protein
H1Q60_RS15245	COG0840	transmembrane signaling receptor activity
H1Q60_RS15250	COG0723	plastoquinol--plastocyanin reductase activity
H1Q60_RS15250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q60_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS15265	COG4903	ComK protein
H1Q60_RS15285	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H1Q60_RS15290	COG2323	membrane
H1Q60_RS15305	COG0420	3'-5' exonuclease activity
H1Q60_RS15310	COG0419	ATPase involved in DNA repair
H1Q60_RS15315	COG1403	HNH endonuclease
H1Q60_RS15355	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1Q60_RS15370	COG0367	asparagine synthase
H1Q60_RS15375	COG1562	ergosterol biosynthetic process
H1Q60_RS15380	COG0534	Mate efflux family protein
H1Q60_RS15385	COG2207	Transcriptional regulator
H1Q60_RS15385	COG1917	Cupin 2, conserved barrel domain protein
H1Q60_RS15390	COG1609	Transcriptional regulator
H1Q60_RS15395	COG0673	inositol 2-dehydrogenase activity
H1Q60_RS15400	COG2318	DinB family
H1Q60_RS15405	COG1279	arginine transmembrane transporter activity
H1Q60_RS15410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q60_RS15415	COG1357	PFAM Pentapeptide repeats (8 copies)
H1Q60_RS15420	COG2153	protein acetylation
H1Q60_RS15425	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1Q60_RS15425	COG0646	methionine synthase
H1Q60_RS15435	COG2996	Protein conserved in bacteria
H1Q60_RS15445	COG0840	transmembrane signaling receptor activity
H1Q60_RS15455	COG1307	EDD domain protein, DegV family
H1Q60_RS15460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1Q60_RS15480	COG0561	phosphatase activity
H1Q60_RS15485	COG1073	alpha beta
H1Q60_RS15490	COG2151	metal-sulfur cluster biosynthetic enzyme
H1Q60_RS15500	COG0277	FAD linked oxidase domain protein
H1Q60_RS15505	COG2271	Major facilitator Superfamily
H1Q60_RS15515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1Q60_RS15525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1Q60_RS15530	COG0505	Belongs to the CarA family
H1Q60_RS15535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H1Q60_RS15540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H1Q60_RS15565	COG1744	ABC transporter substrate-binding protein PnrA-like
H1Q60_RS15580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H1Q60_RS15585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1Q60_RS15590	COG5504	Zn-dependent protease
H1Q60_RS15595	COG0444	Belongs to the ABC transporter superfamily
H1Q60_RS15600	COG4608	Belongs to the ABC transporter superfamily
H1Q60_RS15610	COG0601	transmembrane transport
H1Q60_RS15615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q60_RS15625	COG0180	Tryptophanyl-tRNA synthetase
H1Q60_RS15630	COG4166	transmembrane transport
H1Q60_RS15635	COG0601	transmembrane transport
H1Q60_RS15640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q60_RS15645	COG0444	Belongs to the ABC transporter superfamily
H1Q60_RS15650	COG4608	Belongs to the ABC transporter superfamily
H1Q60_RS15660	COG0456	acetyltransferase
H1Q60_RS15665	COG1393	Belongs to the ArsC family
H1Q60_RS15670	COG0861	Integral membrane protein TerC family
H1Q60_RS15675	COG4862	establishment of competence for transformation
H1Q60_RS15680	COG4469	Competence protein
H1Q60_RS15685	COG1164	Oligoendopeptidase f
H1Q60_RS15700	COG2346	COG2346, Truncated hemoglobins
H1Q60_RS15705	COG0741	lytic transglycosylase activity
H1Q60_RS15710	COG4116	CYTH
H1Q60_RS15720	COG2357	RelA SpoT domain protein
H1Q60_RS15725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1Q60_RS15730	COG0564	pseudouridine synthase activity
H1Q60_RS15740	COG0569	domain protein
H1Q60_RS15740	COG0475	glutathione-regulated potassium exporter activity
H1Q60_RS15745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1Q60_RS15750	COG0352	thiamine-phosphate diphosphorylase activity
H1Q60_RS15755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q60_RS15760	COG2104	thiamine diphosphate biosynthetic process
H1Q60_RS15770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1Q60_RS15775	COG0351	phosphomethylpyrimidine kinase
H1Q60_RS15780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H1Q60_RS15835	COG0210	DNA helicase
H1Q60_RS15855	COG1131	(ABC) transporter
H1Q60_RS15865	COG2153	protein acetylation
H1Q60_RS15875	COG2382	esterase
H1Q60_RS15880	COG0626	cystathionine gamma-synthase activity
H1Q60_RS15885	COG0626	cystathionine gamma-synthase activity
H1Q60_RS15895	COG0582	viral genome integration into host DNA
H1Q60_RS16005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Q60_RS16130	COG5444	nuclease activity
H1Q60_RS16145	COG0135	phosphoribosylanthranilate isomerase activity
H1Q60_RS16160	COG5484	DNA packaging
H1Q60_RS16165	COG2367	Beta-lactamase
H1Q60_RS16170	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1Q60_RS16175	COG0477	Major facilitator Superfamily
H1Q60_RS16180	COG1846	Transcriptional regulator
H1Q60_RS16190	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H1Q60_RS16195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1Q60_RS16200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H1Q60_RS16205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Q60_RS16205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Q60_RS16210	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1Q60_RS16245	COG1285	pathogenesis
H1Q60_RS16260	COG2205	protein histidine kinase activity
H1Q60_RS16270	COG3383	formate dehydrogenase (NAD+) activity
H1Q60_RS16275	COG2427	Protein of unknown function (DUF1641)
H1Q60_RS16280	COG2124	cytochrome p450
H1Q60_RS16285	COG1819	glycosyl
H1Q60_RS16295	COG1587	Uroporphyrinogen-III synthase
H1Q60_RS16300	COG0390	transport system, permease component
H1Q60_RS16305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1Q60_RS16310	COG0697	spore germination
H1Q60_RS16315	COG4297	protein containing double-stranded beta helix domain
H1Q60_RS16325	COG1252	NADH dehydrogenase
H1Q60_RS16340	COG1609	Transcriptional regulator
H1Q60_RS16345	COG0246	Mannitol dehydrogenase
H1Q60_RS16350	COG2721	sulfolactate sulfo-lyase activity
H1Q60_RS16355	COG0745	RESPONSE REGULATOR receiver
H1Q60_RS16360	COG2770	Histidine kinase
H1Q60_RS16360	COG2205	protein histidine kinase activity
H1Q60_RS16380	COG4585	Histidine kinase
H1Q60_RS16385	COG2197	response regulator
H1Q60_RS16420	COG0730	response to heat
H1Q60_RS16425	COG2318	DinB family
H1Q60_RS16430	COG0457	Tetratricopeptide repeat
H1Q60_RS16440	COG5632	N-Acetylmuramoyl-L-alanine amidase
H1Q60_RS16440	COG3409	Peptidoglycan-binding domain 1 protein
H1Q60_RS16440	COG1388	LysM domain
H1Q60_RS16450	COG4195	phage-related replication protein
H1Q60_RS16455	COG2856	Zn peptidase
H1Q60_RS16460	COG1396	sequence-specific DNA binding
H1Q60_RS16470	COG1522	sequence-specific DNA binding
H1Q60_RS16475	COG1484	DNA-dependent DNA replication
H1Q60_RS16495	COG1595	DNA-templated transcription, initiation
H1Q60_RS16500	COG4193	domain, Protein
H1Q60_RS16535	COG3409	Peptidoglycan-binding domain 1 protein
H1Q60_RS16535	COG5632	N-Acetylmuramoyl-L-alanine amidase
H1Q60_RS16550	COG0306	phosphate transporter
H1Q60_RS16555	COG1392	Phosphate transport regulator
H1Q60_RS16560	COG0531	amino acid
H1Q60_RS16565	COG0346	lactoylglutathione lyase activity
H1Q60_RS16570	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H1Q60_RS16575	COG0463	Glycosyl transferase, family 2
H1Q60_RS16585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Q60_RS16590	COG0477	Major facilitator Superfamily
H1Q60_RS16595	COG2362	D-Aminopeptidase
H1Q60_RS16600	COG0601	transmembrane transport
H1Q60_RS16605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q60_RS16610	COG0444	Belongs to the ABC transporter superfamily
H1Q60_RS16615	COG4166	transmembrane transport
H1Q60_RS16620	COG1619	proteins homologs of microcin C7 resistance protein MccF
H1Q60_RS16625	COG4948	Mandelate Racemase Muconate Lactonizing
H1Q60_RS16630	COG0791	NLP P60 protein
H1Q60_RS16635	COG4608	Belongs to the ABC transporter superfamily
H1Q60_RS16640	COG2706	6-phosphogluconolactonase activity
H1Q60_RS16645	COG1834	amidinotransferase
H1Q60_RS16650	COG1607	acyl-coa hydrolase
H1Q60_RS16655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Q60_RS16660	COG2076	Multidrug Resistance protein
H1Q60_RS16665	COG2076	Multidrug Resistance protein
H1Q60_RS16670	COG0788	formyltetrahydrofolate deformylase activity
H1Q60_RS16675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H1Q60_RS16685	COG1764	response to oxidative stress
H1Q60_RS16690	COG1846	Transcriptional regulator
H1Q60_RS16695	COG1764	response to oxidative stress
H1Q60_RS16710	COG0457	Tetratricopeptide repeat
H1Q60_RS16710	COG0463	Glycosyl transferase, family 2
H1Q60_RS16720	COG2814	Major facilitator Superfamily
H1Q60_RS16725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q60_RS16735	COG1404	Belongs to the peptidase S8 family
H1Q60_RS16740	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q60_RS16745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H1Q60_RS16750	COG1122	ATPase activity
H1Q60_RS16755	COG4721	ABC-type cobalt transport system, permease component
H1Q60_RS16760	COG1388	LysM domain
H1Q60_RS16760	COG3858	chitin binding
H1Q60_RS16770	COG2239	Acts as a magnesium transporter
H1Q60_RS16775	COG0789	Transcriptional regulator
H1Q60_RS16790	COG1846	Transcriptional regulator
H1Q60_RS16795	COG0726	polysaccharide deacetylase
H1Q60_RS16800	COG1793	dna ligase
H1Q60_RS16800	COG3285	dna ligase
H1Q60_RS16805	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H1Q60_RS16810	COG0586	Pfam SNARE associated Golgi protein
H1Q60_RS16815	COG0861	Integral membrane protein TerC family
H1Q60_RS16820	COG1191	sigma factor activity
H1Q60_RS16845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1Q60_RS16850	COG2323	membrane
H1Q60_RS16860	COG3594	Acyltransferase
H1Q60_RS16865	COG5002	protein histidine kinase activity
H1Q60_RS16870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1Q60_RS16885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1Q60_RS16890	COG0436	Aminotransferase
H1Q60_RS16920	COG3852	Histidine kinase
H1Q60_RS16925	COG1846	Transcriptional regulator
H1Q60_RS16930	COG1360	Flagellar Motor Protein
H1Q60_RS16935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H1Q60_RS16940	COG0542	response to heat
H1Q60_RS16945	COG3949	Membrane
H1Q60_RS16960	COG0720	synthase
H1Q60_RS16965	COG0602	queuosine metabolic process
H1Q60_RS16970	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H1Q60_RS16975	COG1733	regulation of RNA biosynthetic process
H1Q60_RS16980	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS17000	COG4873	Protein conserved in bacteria
H1Q60_RS17010	COG3773	Cell wall hydrolase
H1Q60_RS17015	COG2244	polysaccharide biosynthetic process
H1Q60_RS17020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q60_RS17025	COG2217	Heavy metal translocating P-type atpase
H1Q60_RS17030	COG0006	proline dipeptidase activity
H1Q60_RS17035	COG1609	Transcriptional regulator
H1Q60_RS17040	COG3711	transcriptional antiterminator
H1Q60_RS17045	COG1263	PTS System
H1Q60_RS17045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Q60_RS17045	COG2190	(PTS) system
H1Q60_RS17050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q60_RS17055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1Q60_RS17065	COG1533	DNA photolyase activity
H1Q60_RS17070	COG0840	transmembrane signaling receptor activity
H1Q60_RS17075	COG2084	Dehydrogenase
H1Q60_RS17085	COG0347	Belongs to the P(II) protein family
H1Q60_RS17090	COG2340	Cysteine-rich secretory protein family
H1Q60_RS17095	COG0768	penicillin binding
H1Q60_RS17100	COG4191	Histidine kinase
H1Q60_RS17105	COG0436	Aminotransferase
H1Q60_RS17115	COG0835	chemotaxis
H1Q60_RS17115	COG0784	Response regulator, receiver
H1Q60_RS17125	COG2814	Major facilitator Superfamily
H1Q60_RS17130	COG1376	ErfK ybiS ycfS ynhG family protein
H1Q60_RS17135	COG1408	metallophosphoesterase
H1Q60_RS17140	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS17150	COG2200	EAL domain
H1Q60_RS17155	COG4703	Protein of unknown function (DUF1797)
H1Q60_RS17160	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H1Q60_RS17170	COG0517	IMP dehydrogenase activity
H1Q60_RS17175	COG0583	DNA-binding transcription factor activity
H1Q60_RS17180	COG0716	FMN binding
H1Q60_RS17190	COG0716	FMN binding
H1Q60_RS17210	COG0668	transmembrane transport
H1Q60_RS17215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q60_RS17235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1Q60_RS17240	COG0303	'Molybdopterin
H1Q60_RS17245	COG1763	Mo-molybdopterin cofactor biosynthetic process
H1Q60_RS17250	COG0314	molybdopterin synthase activity
H1Q60_RS17255	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H1Q60_RS17265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q60_RS17270	COG1136	(ABC) transporter
H1Q60_RS17275	COG0577	efflux transmembrane transporter activity
H1Q60_RS17280	COG1349	DNA-binding transcription factor activity
H1Q60_RS17285	COG1105	Belongs to the carbohydrate kinase PfkB family
H1Q60_RS17290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Q60_RS17290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Q60_RS17290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q60_RS17295	COG0681	Belongs to the peptidase S26 family
H1Q60_RS17305	COG0488	(ABC) transporter
H1Q60_RS17310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H1Q60_RS17315	COG2309	aminopeptidase activity
H1Q60_RS17325	COG1077	Cell shape determining protein MreB Mrl
H1Q60_RS17330	COG2002	toxin-antitoxin pair type II binding
H1Q60_RS17335	COG3852	Histidine kinase
H1Q60_RS17340	COG2105	PFAM AIG2 family protein
H1Q60_RS17340	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H1Q60_RS17345	COG0569	domain protein
H1Q60_RS17355	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H1Q60_RS17365	COG0561	phosphatase activity
H1Q60_RS17370	COG0242	peptide deformylase activity
H1Q60_RS17380	COG0497	DNA recombination
H1Q60_RS17390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS17390	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS17390	COG3321	synthase
H1Q60_RS17390	COG4221	oxidoreductase activity
H1Q60_RS17395	COG3321	synthase
H1Q60_RS17395	COG0300	oxidoreductase activity
H1Q60_RS17395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1Q60_RS17395	COG4221	oxidoreductase activity
H1Q60_RS17400	COG4221	oxidoreductase activity
H1Q60_RS17400	COG3321	synthase
H1Q60_RS17400	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS17400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS17405	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS17405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS17405	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q60_RS17405	COG0300	oxidoreductase activity
H1Q60_RS17405	COG3321	synthase
H1Q60_RS17410	COG0300	oxidoreductase activity
H1Q60_RS17410	COG3321	synthase
H1Q60_RS17410	COG4221	oxidoreductase activity
H1Q60_RS17410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1Q60_RS17415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1Q60_RS17415	COG0300	oxidoreductase activity
H1Q60_RS17415	COG3321	synthase
H1Q60_RS17415	COG4221	oxidoreductase activity
H1Q60_RS17420	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS17420	COG4221	oxidoreductase activity
H1Q60_RS17420	COG3321	synthase
H1Q60_RS17420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS17425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1Q60_RS17430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1Q60_RS17435	COG0022	dehydrogenase e1 component
H1Q60_RS17440	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q60_RS17445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1Q60_RS17450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q60_RS17465	COG1982	Orn Lys Arg decarboxylase major
H1Q60_RS17485	COG0483	inositol monophosphate 1-phosphatase activity
H1Q60_RS17495	COG3227	Zinc metalloprotease (Elastase)
H1Q60_RS17510	COG1595	DNA-templated transcription, initiation
H1Q60_RS17540	COG4896	Protein conserved in bacteria
H1Q60_RS17550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H1Q60_RS17555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H1Q60_RS17645	COG0457	Tetratricopeptide repeat
H1Q60_RS17660	COG2433	Pfam Transposase IS66
H1Q60_RS17670	COG0739	heme binding
H1Q60_RS17670	COG0741	lytic transglycosylase activity
H1Q60_RS17670	COG1196	nuclear chromosome segregation
H1Q60_RS17805	COG2066	Belongs to the glutaminase family
H1Q60_RS17815	COG0772	Belongs to the SEDS family
H1Q60_RS17820	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H1Q60_RS17835	COG2010	Cytochrome c
H1Q60_RS17835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1Q60_RS17840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1Q60_RS17845	COG1845	cytochrome c oxidase, subunit III
H1Q60_RS17850	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1Q60_RS17855	COG3336	cytochrome c oxidase
H1Q60_RS17865	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H1Q60_RS17870	COG2340	Cysteine-rich secretory protein family
H1Q60_RS17885	COG3679	Belongs to the UPF0342 family
H1Q60_RS17895	COG0742	ribosomal rna small subunit methyltransferase
H1Q60_RS17905	COG3314	Sporulation integral membrane protein YlbJ
H1Q60_RS17910	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1Q60_RS17915	COG3480	Lon protease (S16) C-terminal proteolytic domain
H1Q60_RS17925	COG1399	metal-binding, possibly nucleic acid-binding protein
H1Q60_RS17945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H1Q60_RS17965	COG4839	cell division protein FtsL
H1Q60_RS17975	COG0768	penicillin binding
H1Q60_RS17995	COG0772	Belongs to the SEDS family
H1Q60_RS18010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1Q60_RS18015	COG0849	cell division
H1Q60_RS18020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1Q60_RS18025	COG4412	M6 family metalloprotease domain protein
H1Q60_RS18025	COG1404	Belongs to the peptidase S8 family
H1Q60_RS18035	COG1191	sigma factor activity
H1Q60_RS18040	COG1191	sigma factor activity
H1Q60_RS18045	COG1119	ATPase activity
H1Q60_RS18050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q60_RS18055	COG1873	PFAM PRC-barrel domain
H1Q60_RS18065	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H1Q60_RS18075	COG0762	integral membrane protein
H1Q60_RS18080	COG2302	S4 RNA-binding domain
H1Q60_RS18085	COG3599	regulation of cell shape
H1Q60_RS18090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1Q60_RS18095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1Q60_RS18105	COG0564	pseudouridine synthase activity
H1Q60_RS18115	COG2233	PERMEase
H1Q60_RS18125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H1Q60_RS18130	COG0505	Belongs to the CarA family
H1Q60_RS18135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H1Q60_RS18150	COG0284	orotidine-5'-phosphate decarboxylase activity
H1Q60_RS18155	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H1Q60_RS18165	COG0306	phosphate transporter
H1Q60_RS18180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1Q60_RS18185	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
H1Q60_RS18190	COG1648	precorrin-2 dehydrogenase activity
H1Q60_RS18205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1Q60_RS18210	COG1561	YicC-like family, N-terminal region
H1Q60_RS18220	COG0194	GDP metabolic process
H1Q60_RS18230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1Q60_RS18235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1Q60_RS18240	COG0242	peptide deformylase activity
H1Q60_RS18250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H1Q60_RS18250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H1Q60_RS18260	COG0631	protein serine/threonine phosphatase activity
H1Q60_RS18265	COG2815	serine threonine protein kinase
H1Q60_RS18265	COG0515	serine threonine protein kinase
H1Q60_RS18275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1Q60_RS18280	COG1564	THIamine pyrophosphokinase
H1Q60_RS18295	COG1302	Protein conserved in bacteria
H1Q60_RS18300	COG1461	Dihydroxyacetone kinase
H1Q60_RS18305	COG1760	l-serine dehydratase
H1Q60_RS18310	COG1760	l-serine dehydratase
H1Q60_RS18315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1Q60_RS18330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1Q60_RS18335	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS18350	COG1196	nuclear chromosome segregation
H1Q60_RS18355	COG0552	protein localization to endoplasmic reticulum
H1Q60_RS18370	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1Q60_RS18380	COG1837	Belongs to the UPF0109 family
H1Q60_RS18405	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H1Q60_RS18420	COG2257	FlhB HrpN YscU SpaS Family
H1Q60_RS18430	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1Q60_RS18435	COG0758	DNA mediated transformation
H1Q60_RS18440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1Q60_RS18450	COG4974	Belongs to the 'phage' integrase family
H1Q60_RS18470	COG1815	bacterial-type flagellum-dependent cell motility
H1Q60_RS18475	COG1558	bacterial-type flagellum-dependent cell motility
H1Q60_RS18480	COG1677	Flagellar hook-basal body complex protein FliE
H1Q60_RS18485	COG1766	The M ring may be actively involved in energy transduction
H1Q60_RS18490	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1Q60_RS18495	COG1317	bacterial-type flagellum organization
H1Q60_RS18500	COG1157	protein secretion by the type III secretion system
H1Q60_RS18505	COG2882	bacterial-type flagellum organization
H1Q60_RS18510	COG3334	PFAM MgtE intracellular
H1Q60_RS18515	COG3144	bacterial-type flagellum assembly
H1Q60_RS18520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H1Q60_RS18525	COG4786	Flagellar basal body rod
H1Q60_RS18530	COG1582	Flagellar protein (FlbD)
H1Q60_RS18535	COG1580	Controls the rotational direction of flagella during chemotaxis
H1Q60_RS18540	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1Q60_RS18545	COG1776	CheC inhibitor of MCP methylation
H1Q60_RS18545	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1Q60_RS18550	COG2201	protein-glutamate methylesterase activity
H1Q60_RS18555	COG3190	flagellar
H1Q60_RS18560	COG1338	Plays a role in the flagellum-specific transport system
H1Q60_RS18565	COG1987	bacterial-type flagellum assembly
H1Q60_RS18570	COG1684	flagellar biosynthetic protein fliR
H1Q60_RS18575	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H1Q60_RS18580	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H1Q60_RS18585	COG1419	protein localization to endoplasmic reticulum
H1Q60_RS18590	COG0455	bacterial-type flagellum organization
H1Q60_RS18595	COG2201	protein-glutamate methylesterase activity
H1Q60_RS18600	COG0643	Histidine kinase
H1Q60_RS18600	COG2198	Histidine kinase
H1Q60_RS18605	COG0835	chemotaxis
H1Q60_RS18610	COG1776	CheC inhibitor of MCP methylation
H1Q60_RS18620	COG1191	sigma factor activity
H1Q60_RS18650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1Q60_RS18655	COG4589	Belongs to the CDS family
H1Q60_RS18665	COG0750	zinc metalloprotease
H1Q60_RS18675	COG2176	DNA-directed DNA polymerase activity
H1Q60_RS18685	COG0195	Participates in both transcription termination and antitermination
H1Q60_RS18690	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H1Q60_RS18695	COG1358	cellular component organization or biogenesis
H1Q60_RS18705	COG1550	Protein conserved in bacteria
H1Q60_RS18720	COG0196	riboflavin kinase activity
H1Q60_RS18735	COG0726	polysaccharide deacetylase
H1Q60_RS18740	COG0612	Peptidase, M16
H1Q60_RS18745	COG1873	PFAM PRC-barrel domain
H1Q60_RS18750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1Q60_RS18755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1Q60_RS18760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1Q60_RS18765	COG0527	aspartate kinase activity
H1Q60_RS18775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H1Q60_RS18780	COG0740	serine-type endopeptidase activity
H1Q60_RS18790	COG4980	gas vesicle protein
H1Q60_RS18790	COG1674	ftsk spoiiie
H1Q60_RS18795	COG2188	Transcriptional regulator
H1Q60_RS18800	COG2814	Major facilitator Superfamily
H1Q60_RS18805	COG1846	Transcriptional regulator
H1Q60_RS18810	COG2409	Drug exporters of the RND superfamily
H1Q60_RS18810	COG1033	growth of symbiont in host cell
H1Q60_RS18815	COG0612	Peptidase, M16
H1Q60_RS18820	COG0612	Peptidase, M16
H1Q60_RS18825	COG0300	oxidoreductase activity
H1Q60_RS18840	COG1426	Protein conserved in bacteria
H1Q60_RS18845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1Q60_RS18860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1Q60_RS18870	COG1692	metallophosphoesterase
H1Q60_RS18875	COG2359	stage V sporulation protein S
H1Q60_RS18895	COG4550	Control of competence regulator ComK, YlbF/YmcA
H1Q60_RS18915	COG0582	viral genome integration into host DNA
H1Q60_RS18955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1Q60_RS18960	COG3425	synthase
H1Q60_RS18965	COG1024	Enoyl-CoA hydratase
H1Q60_RS18995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS18995	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS18995	COG4221	oxidoreductase activity
H1Q60_RS18995	COG3321	synthase
H1Q60_RS19000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1Q60_RS19000	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1Q60_RS19000	COG3321	synthase
H1Q60_RS19000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1Q60_RS19005	COG2124	cytochrome p450
H1Q60_RS19010	COG3209	COG3209 Rhs family protein
H1Q60_RS19015	COG3619	membrane
H1Q60_RS19025	COG1404	Belongs to the peptidase S8 family
H1Q60_RS19035	COG4195	phage-related replication protein
H1Q60_RS19040	COG1764	response to oxidative stress
H1Q60_RS19050	COG2076	Multidrug Resistance protein
H1Q60_RS19090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1Q60_RS19095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1Q60_RS19100	COG4112	unkown
H1Q60_RS19105	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Q60_RS19110	COG0464	growth
H1Q60_RS19115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1Q60_RS19120	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H1Q60_RS19125	COG0789	Transcriptional regulator
H1Q60_RS19130	COG0174	glutamine synthetase
H1Q60_RS19135	COG0582	viral genome integration into host DNA
H1Q60_RS19150	COG1525	nuclease
H1Q60_RS19155	COG4282	regulation of fungal-type cell wall biogenesis
H1Q60_RS19165	COG5444	nuclease activity
H1Q60_RS19200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1Q60_RS19205	COG0457	Tetratricopeptide repeat
H1Q60_RS19225	COG3409	Peptidoglycan-binding domain 1 protein
H1Q60_RS19225	COG5632	N-Acetylmuramoyl-L-alanine amidase
H1Q60_RS19250	COG0739	heme binding
H1Q60_RS19250	COG0741	lytic transglycosylase activity
H1Q60_RS19250	COG1196	nuclear chromosome segregation
H1Q60_RS19415	COG0776	regulation of translation
H1Q60_RS19470	COG0210	DNA helicase
H1Q60_RS19475	COG3645	SOS response
H1Q60_RS19475	COG3646	Phage regulatory protein
H1Q60_RS19505	COG3655	Transcriptional regulator
H1Q60_RS19510	COG3655	Transcriptional regulator
H1Q60_RS19605	COG0582	viral genome integration into host DNA
H1Q60_RS19620	COG3655	Transcriptional regulator
H1Q60_RS19730	COG1793	dna ligase
H1Q60_RS19735	COG2135	peptidase activity
H1Q60_RS19760	COG4195	phage-related replication protein
H1Q60_RS19765	COG3420	alginic acid biosynthetic process
H1Q60_RS19765	COG5434	Belongs to the glycosyl hydrolase 28 family
H1Q60_RS19805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1Q60_RS19815	COG3584	3D domain protein
H1Q60_RS19835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H1Q60_RS19840	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
H1Q60_RS19925	COG1780	Probably involved in ribonucleotide reductase function
H1Q60_RS19930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1Q60_RS19930	COG1372	Participates in initiation and elongation during chromosome replication
H1Q60_RS19965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q60_RS19975	COG0756	dUTP diphosphatase activity
H1Q60_RS19995	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H1Q60_RS20000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1Q60_RS20025	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1Q60_RS20070	COG3331	DNA recombination
H1Q60_RS20085	COG2211	Major facilitator Superfamily
H1Q60_RS20090	COG3507	Belongs to the glycosyl hydrolase 43 family
H1Q60_RS20105	COG1070	Carbohydrate kinase
H1Q60_RS20110	COG0574	Belongs to the PEP-utilizing enzyme family
H1Q60_RS20110	COG3848	Pyruvate phosphate dikinase
H1Q60_RS20130	COG2378	regulation of single-species biofilm formation
H1Q60_RS20135	COG2318	DinB family
H1Q60_RS20140	COG1064	alcohol dehydrogenase
H1Q60_RS20165	COG5444	nuclease activity
H1Q60_RS20225	COG3397	chitin binding
H1Q60_RS20245	COG5434	Belongs to the glycosyl hydrolase 28 family
H1Q60_RS20250	COG0756	dUTP diphosphatase activity
H1Q60_RS20255	COG4195	phage-related replication protein
H1Q60_RS20290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Q60_RS20300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1Q60_RS20320	COG0785	Cytochrome C biogenesis protein
H1Q60_RS20325	COG2201	protein-glutamate methylesterase activity
H1Q60_RS20330	COG4846	Membrane protein involved in cytochrome C biogenesis
H1Q60_RS20340	COG0071	Belongs to the small heat shock protein (HSP20) family
H1Q60_RS20355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1Q60_RS20360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q60_RS20380	COG0824	Thioesterase
H1Q60_RS20390	COG4841	protein insertion into membrane
H1Q60_RS20400	COG1832	CoA-binding protein
H1Q60_RS20405	COG0187	DNA topoisomerase II activity
H1Q60_RS20410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H1Q60_RS20420	COG2271	Major facilitator Superfamily
H1Q60_RS20475	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q60_RS20480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1Q60_RS20485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1Q60_RS20490	COG2610	gluconate transmembrane transporter activity
H1Q60_RS20495	COG2124	cytochrome p450
H1Q60_RS20515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H1Q60_RS20525	COG2246	polysaccharide biosynthetic process
H1Q60_RS20530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1Q60_RS20535	COG0586	Pfam SNARE associated Golgi protein
H1Q60_RS20540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1Q60_RS20545	COG1024	Enoyl-CoA hydratase
H1Q60_RS20550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1Q60_RS20555	COG0511	ligase activity, forming carbon-carbon bonds
H1Q60_RS20560	COG0439	Biotin carboxylase
H1Q60_RS20565	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q60_RS20570	COG1960	acyl-CoA dehydrogenase activity
H1Q60_RS20575	COG1649	PFAM Uncharacterised BCR, COG1649
H1Q60_RS20585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q60_RS20585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1Q60_RS20600	COG2323	membrane
H1Q60_RS20605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1Q60_RS20615	COG2323	membrane
H1Q60_RS20630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H1Q60_RS20675	COG2027	D-alanyl-D-alanine carboxypeptidase
H1Q60_RS20680	COG2017	converts alpha-aldose to the beta-anomer
H1Q60_RS20685	COG0534	Mate efflux family protein
H1Q60_RS20700	COG0582	viral genome integration into host DNA
H1Q60_RS20705	COG0166	Belongs to the GPI family
H1Q60_RS20710	COG0405	Gamma-glutamyltransferase
H1Q60_RS20720	COG0640	Transcriptional regulator
H1Q60_RS20725	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H1Q60_RS20735	COG0604	alcohol dehydrogenase
H1Q60_RS20745	COG0493	'glutamate synthase
H1Q60_RS20750	COG0070	glutamate synthase
H1Q60_RS20750	COG0067	glutamate synthase
H1Q60_RS20750	COG0069	glutamate synthase activity
H1Q60_RS20755	COG0583	DNA-binding transcription factor activity
H1Q60_RS20760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H1Q60_RS20775	COG0300	oxidoreductase activity
H1Q60_RS20780	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H1Q60_RS20790	COG2814	Major facilitator Superfamily
H1Q60_RS20795	COG1070	Carbohydrate kinase
H1Q60_RS20805	COG0243	molybdopterin cofactor binding
H1Q60_RS20830	COG3328	transposase activity
H1Q60_RS20840	COG5444	nuclease activity
H1Q60_RS20845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1Q60_RS20850	COG0662	Cupin 2, conserved barrel domain protein
H1Q60_RS20850	COG2207	Transcriptional regulator
H1Q60_RS20855	COG1309	transcriptional regulator
H1Q60_RS20860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q60_RS20870	COG0640	Transcriptional regulator
H1Q60_RS20875	COG0741	lytic transglycosylase activity
H1Q60_RS20880	COG2322	membrane
H1Q60_RS20895	COG1619	proteins homologs of microcin C7 resistance protein MccF
H1Q60_RS20905	COG1388	LysM domain
H1Q60_RS20905	COG3584	3D domain protein
H1Q60_RS20910	COG0514	ATP-dependent DNA helicase (RecQ)
H1Q60_RS20920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1Q60_RS20925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1Q60_RS20970	COG1012	belongs to the aldehyde dehydrogenase family
H1Q60_RS20975	COG1657	PFAM Prenyltransferase squalene oxidase
H1Q60_RS20980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1Q60_RS20985	COG0733	neurotransmitter:sodium symporter activity
H1Q60_RS20990	COG0385	Bile acid
H1Q60_RS20995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q60_RS21000	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q60_RS21010	COG4548	von Willebrand factor, type A
H1Q60_RS21015	COG0714	Associated with various cellular activities
H1Q60_RS21020	COG2032	superoxide dismutase activity
H1Q60_RS21025	COG0791	NLP P60 protein
H1Q60_RS21025	COG1388	LysM domain
H1Q60_RS21030	COG1819	glycosyl
H1Q60_RS21035	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H1Q60_RS21040	COG0534	Mate efflux family protein
H1Q60_RS21045	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q60_RS21050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H1Q60_RS21055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H1Q60_RS21065	COG2962	Rard protein
H1Q60_RS21080	COG1942	4-Oxalocrotonate Tautomerase
H1Q60_RS21090	COG1733	regulation of RNA biosynthetic process
H1Q60_RS21095	COG0778	Nitroreductase
H1Q60_RS21105	COG0346	lactoylglutathione lyase activity
H1Q60_RS21115	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1Q60_RS21130	COG2188	Transcriptional regulator
H1Q60_RS21135	COG0793	Belongs to the peptidase S41A family
H1Q60_RS21135	COG3409	Peptidoglycan-binding domain 1 protein
H1Q60_RS21140	COG2226	methyltransferase
H1Q60_RS21150	COG1876	peptidase activity
H1Q60_RS21170	COG0671	phosphoesterase, PA-phosphatase related
H1Q60_RS21200	COG1509	lysine 2,3-aminomutase activity
H1Q60_RS21205	COG0456	acetyltransferase
H1Q60_RS21210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q60_RS21215	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1Q60_RS21220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1Q60_RS21225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H1Q60_RS21230	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1Q60_RS21240	COG0456	acetyltransferase
H1Q60_RS21245	COG0463	Glycosyl transferase, family 2
H1Q60_RS21260	COG4641	Protein conserved in bacteria