locus-tag	class	description
M2893_RS00010	COG0592	DNA-directed DNA polymerase activity
M2893_RS00015	COG2501	S4 domain
M2893_RS00030	COG0187	DNA topoisomerase II activity
M2893_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M2893_RS00070	COG0516	GMP reductase activity
M2893_RS00070	COG0517	IMP dehydrogenase activity
M2893_RS00075	COG1686	Belongs to the peptidase S11 family
M2893_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
M2893_RS00105	COG1428	Deoxynucleoside kinase
M2893_RS00110	COG1428	Deoxynucleoside kinase
M2893_RS00115	COG1388	LysM domain
M2893_RS00115	COG3858	chitin binding
M2893_RS00120	COG1335	isochorismatase
M2893_RS00125	COG0590	tRNA wobble adenosine to inosine editing
M2893_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M2893_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
M2893_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
M2893_RS00195	COG3853	Toxic anion resistance protein (TelA)
M2893_RS00200	COG1982	Orn Lys Arg decarboxylase major
M2893_RS00210	COG3870	Protein conserved in bacteria
M2893_RS00215	COG1728	Protein conserved in bacteria
M2893_RS00220	COG0470	DNA polymerase III
M2893_RS00225	COG1774	PSP1 C-terminal conserved region
M2893_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M2893_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M2893_RS00250	COG2002	toxin-antitoxin pair type II binding
M2893_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M2893_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M2893_RS00260	COG0084	hydrolase, TatD family'
M2893_RS00265	COG3583	domain protein
M2893_RS00265	COG3584	3D domain protein
M2893_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M2893_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M2893_RS00285	COG4466	Protein conserved in bacteria
M2893_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M2893_RS00305	COG0251	oxidation-reduction process
M2893_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M2893_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M2893_RS00345	COG2002	toxin-antitoxin pair type II binding
M2893_RS00350	COG2244	polysaccharide biosynthetic process
M2893_RS00355	COG3956	TIGRFAM MazG family protein
M2893_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M2893_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M2893_RS00380	COG1098	S1 RNA binding domain
M2893_RS00395	COG2208	phosphoserine phosphatase activity
M2893_RS00400	COG2304	oxidoreductase activity
M2893_RS00405	COG0515	serine threonine protein kinase
M2893_RS00410	COG0037	tRNA processing
M2893_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M2893_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M2893_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M2893_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M2893_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M2893_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
M2893_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M2893_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M2893_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M2893_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M2893_RS00475	COG1396	sequence-specific DNA binding
M2893_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M2893_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
M2893_RS00565	COG4463	regulation of RNA biosynthetic process
M2893_RS00570	COG3880	PFAM UvrB UvrC protein
M2893_RS00580	COG0542	response to heat
M2893_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M2893_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
M2893_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
M2893_RS00615	COG1045	serine acetyltransferase
M2893_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
M2893_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M2893_RS00635	COG3688	RNA-binding protein containing a PIN domain
M2893_RS00640	COG1595	DNA-templated transcription, initiation
M2893_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M2893_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
M2893_RS00680	COG2813	Specifically methylates the guanine in position
M2893_RS00695	COG1358	cellular component organization or biogenesis
M2893_RS00720	COG0596	Alpha beta hydrolase
M2893_RS00830	COG0201	protein transport
M2893_RS00840	COG0024	Methionine aminopeptidase
M2893_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M2893_RS00880	COG1122	ATPase activity
M2893_RS00885	COG1122	ATPase activity
M2893_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M2893_RS00910	COG2226	methyltransferase
M2893_RS00915	COG2318	DinB family
M2893_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
M2893_RS00930	COG0489	protein tyrosine kinase activity
M2893_RS00940	COG2194	sulfuric ester hydrolase activity
M2893_RS00945	COG0726	polysaccharide deacetylase
M2893_RS01005	COG0738	Major facilitator superfamily
M2893_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M2893_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
M2893_RS01030	COG0385	Bile acid
M2893_RS01035	COG2819	hydrolase of the alpha beta superfamily
M2893_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2893_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2893_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M2893_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M2893_RS01055	COG2207	Transcriptional regulator
M2893_RS01060	COG3876	Protein conserved in bacteria
M2893_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
M2893_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M2893_RS01075	COG1263	PTS System
M2893_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M2893_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M2893_RS01090	COG1683	Conserved Protein
M2893_RS01120	COG1595	DNA-templated transcription, initiation
M2893_RS01125	COG5662	AntiSigma factor
M2893_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M2893_RS01135	COG4856	YbbR-like protein
M2893_RS01165	COG1346	cytolysis
M2893_RS01170	COG1380	Effector of murein hydrolase LrgA
M2893_RS01175	COG1846	Transcriptional regulator
M2893_RS01180	COG1113	amino acid transport
M2893_RS01185	COG1011	Hydrolase
M2893_RS01190	COG4585	Histidine kinase
M2893_RS01195	COG2197	response regulator
M2893_RS01200	COG1131	(ABC) transporter
M2893_RS01220	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M2893_RS01240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS01240	COG3321	synthase
M2893_RS01240	COG4221	oxidoreductase activity
M2893_RS01245	COG0300	oxidoreductase activity
M2893_RS01245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS01245	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS01245	COG3321	synthase
M2893_RS01245	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS01285	COG0531	amino acid
M2893_RS01290	COG0584	glycerophosphoryl diester phosphodiesterase
M2893_RS01295	COG2271	Major facilitator Superfamily
M2893_RS01305	COG2368	4-hydroxyphenylacetate
M2893_RS01315	COG3409	Peptidoglycan-binding domain 1 protein
M2893_RS01330	COG0371	Dehydrogenase
M2893_RS01340	COG1183	phosphatidylcholine synthase activity
M2893_RS01345	COG0586	Pfam SNARE associated Golgi protein
M2893_RS01350	COG0688	phosphatidylethanolamine metabolic process
M2893_RS01365	COG1301	dicarboxylic acid transport
M2893_RS01370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M2893_RS01375	COG0833	amino acid
M2893_RS01380	COG2040	homocysteine
M2893_RS01385	COG1115	amino acid carrier protein
M2893_RS01390	COG2066	Belongs to the glutaminase family
M2893_RS01395	COG4191	Histidine kinase
M2893_RS01400	COG0784	Response regulator, receiver
M2893_RS01405	COG3173	Aminoglycoside phosphotransferase
M2893_RS01415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M2893_RS01420	COG0778	Nitroreductase
M2893_RS01425	COG0346	lactoylglutathione lyase activity
M2893_RS01430	COG2259	Doxx family
M2893_RS01435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS01450	COG3773	Cell wall hydrolase
M2893_RS01455	COG3540	Alkaline phosphatase
M2893_RS01460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M2893_RS01465	COG0805	protein transport
M2893_RS01475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M2893_RS01480	COG0477	Major facilitator Superfamily
M2893_RS01485	COG1309	transcriptional regulator
M2893_RS01490	COG0252	asparaginase activity
M2893_RS01495	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
M2893_RS01500	COG1405	negative regulation of cell septum assembly
M2893_RS01500	COG3012	SEC-C Motif Domain Protein
M2893_RS01505	COG0667	Aldo Keto reductase
M2893_RS01515	COG1595	DNA-templated transcription, initiation
M2893_RS01520	COG1595	DNA-templated transcription, initiation
M2893_RS01525	COG1876	peptidase activity
M2893_RS01530	COG0457	Tetratricopeptide repeat
M2893_RS01535	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS01545	COG0803	Belongs to the bacterial solute-binding protein 9 family
M2893_RS01550	COG1121	(ABC) transporter
M2893_RS01555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M2893_RS01560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M2893_RS01565	COG2310	stress, protein
M2893_RS01570	COG2310	stress, protein
M2893_RS01575	COG2310	stress, protein
M2893_RS01580	COG0861	Integral membrane protein TerC family
M2893_RS01590	COG3853	Toxic anion resistance protein (TelA)
M2893_RS01595	COG0477	Major facilitator Superfamily
M2893_RS01600	COG4175	Glycine betaine
M2893_RS01600	COG0517	IMP dehydrogenase activity
M2893_RS01605	COG4176	ABC-type proline glycine betaine transport system permease component
M2893_RS01610	COG2113	Glycine betaine
M2893_RS01615	COG1473	amidohydrolase
M2893_RS01620	COG1288	antiporter activity
M2893_RS01630	COG0366	Alpha amylase catalytic
M2893_RS01640	COG2814	Major facilitator Superfamily
M2893_RS01645	COG1846	Transcriptional regulator
M2893_RS01650	COG1280	lysine exporter protein (LysE YggA)
M2893_RS01655	COG3403	YqcI/YcgG family
M2893_RS01660	COG1113	amino acid transport
M2893_RS01665	COG3665	Urea carboxylase-associated protein
M2893_RS01680	COG1660	Displays ATPase and GTPase activities
M2893_RS01690	COG2271	Major facilitator Superfamily
M2893_RS01695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
M2893_RS01700	COG3458	cephalosporin-C deacetylase activity
M2893_RS01705	COG3541	Predicted nucleotidyltransferase
M2893_RS01710	COG0506	proline dehydrogenase activity
M2893_RS01715	COG1012	belongs to the aldehyde dehydrogenase family
M2893_RS01720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M2893_RS01725	COG2508	Transcriptional regulator
M2893_RS01735	COG1587	Uroporphyrinogen-III synthase
M2893_RS01735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M2893_RS01740	COG2146	nitrite reductase [NAD(P)H] activity
M2893_RS01745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M2893_RS01755	COG0523	cobalamin synthesis protein
M2893_RS01760	COG1063	alcohol dehydrogenase
M2893_RS01765	COG1714	RDD family
M2893_RS01790	COG3209	COG3209 Rhs family protein
M2893_RS01795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M2893_RS01800	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
M2893_RS01805	COG1733	regulation of RNA biosynthetic process
M2893_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS01840	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M2893_RS01855	COG2364	Membrane
M2893_RS01860	COG1126	abc transporter atp-binding protein
M2893_RS01865	COG0765	amino acid transport
M2893_RS01870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M2893_RS01875	COG0583	DNA-binding transcription factor activity
M2893_RS01880	COG0163	prenyltransferase activity
M2893_RS01885	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
M2893_RS01900	COG3104	oligopeptide transport
M2893_RS01905	COG5434	Belongs to the glycosyl hydrolase 28 family
M2893_RS01915	COG0697	spore germination
M2893_RS01925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M2893_RS01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M2893_RS01935	COG0456	acetyltransferase
M2893_RS01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M2893_RS01945	COG0765	amino acid transport
M2893_RS01950	COG1126	abc transporter atp-binding protein
M2893_RS01955	COG1473	amidohydrolase
M2893_RS01960	COG2079	MmgE PrpD family protein
M2893_RS01965	COG1136	(ABC) transporter
M2893_RS01970	COG0577	efflux transmembrane transporter activity
M2893_RS01975	COG0745	RESPONSE REGULATOR receiver
M2893_RS01980	COG3850	Histidine kinase
M2893_RS01980	COG5002	protein histidine kinase activity
M2893_RS01985	COG0457	Tetratricopeptide repeat
M2893_RS02000	COG0527	aspartate kinase activity
M2893_RS02005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2893_RS02010	COG4605	iron ion homeostasis
M2893_RS02015	COG4604	ABC transporter, ATP-binding protein
M2893_RS02020	COG4607	ABC-type enterochelin transport system periplasmic component
M2893_RS02025	COG2814	Major facilitator Superfamily
M2893_RS02030	COG1309	transcriptional regulator
M2893_RS02035	COG0778	Nitroreductase
M2893_RS02040	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M2893_RS02045	COG0640	Transcriptional regulator
M2893_RS02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M2893_RS02055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M2893_RS02060	COG1012	belongs to the aldehyde dehydrogenase family
M2893_RS02065	COG4975	Glucose uptake
M2893_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS02075	COG4549	nuclear export factor GLE1
M2893_RS02080	COG1276	copper resistance
M2893_RS02080	COG2372	response to copper ion
M2893_RS02085	COG1349	DNA-binding transcription factor activity
M2893_RS02095	COG2213	PTS system mannitol-specific
M2893_RS02100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M2893_RS02110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M2893_RS02120	COG0561	phosphatase activity
M2893_RS02130	COG1914	H( )-stimulated, divalent metal cation uptake system
M2893_RS02140	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M2893_RS02145	COG1984	allophanate hydrolase subunit 2
M2893_RS02150	COG1414	Transcriptional regulator
M2893_RS02155	COG2755	lipolytic protein G-D-S-L family
M2893_RS02165	COG2329	Antibiotic biosynthesis monooxygenase
M2893_RS02170	COG0768	penicillin binding
M2893_RS02175	COG4989	oxidoreductase activity
M2893_RS02180	COG3711	transcriptional antiterminator
M2893_RS02185	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS02195	COG1917	Cupin 2, conserved barrel domain protein
M2893_RS02200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M2893_RS02205	COG3871	stress protein (general stress protein 26)
M2893_RS02215	COG2814	Major facilitator Superfamily
M2893_RS02220	COG1522	sequence-specific DNA binding
M2893_RS02225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M2893_RS02225	COG0551	DNA topoisomerase type I activity
M2893_RS02230	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M2893_RS02235	COG3706	GGDEF domain
M2893_RS02240	COG5298	Protein conserved in bacteria
M2893_RS02245	COG1215	transferase activity, transferring glycosyl groups
M2893_RS02255	COG0531	amino acid
M2893_RS02260	COG0494	nUDIX hydrolase
M2893_RS02265	COG0028	Belongs to the TPP enzyme family
M2893_RS02285	COG0457	Tetratricopeptide repeat
M2893_RS02310	COG1914	H( )-stimulated, divalent metal cation uptake system
M2893_RS02330	COG2076	Multidrug Resistance protein
M2893_RS02335	COG2217	Heavy metal translocating P-type atpase
M2893_RS02340	COG3729	General stress protein
M2893_RS02350	COG2329	Antibiotic biosynthesis monooxygenase
M2893_RS02355	COG3546	catalase activity
M2893_RS02360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M2893_RS02365	COG3290	protein histidine kinase activity
M2893_RS02370	COG4565	transcriptional regulatory protein
M2893_RS02375	COG1301	dicarboxylic acid transport
M2893_RS02380	COG0628	permease
M2893_RS02385	COG1131	(ABC) transporter
M2893_RS02390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M2893_RS02400	COG1960	acyl-CoA dehydrogenase activity
M2893_RS02415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M2893_RS02420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS02430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M2893_RS02435	COG0513	Belongs to the DEAD box helicase family
M2893_RS02440	COG3402	PFAM membrane-flanked domain
M2893_RS02445	COG3428	Bacterial PH domain
M2893_RS02450	COG0705	Rhomboid family
M2893_RS02460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M2893_RS02465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M2893_RS02470	COG0864	Transcriptional regulator
M2893_RS02475	COG2337	Toxic component of a toxin-antitoxin (TA) module
M2893_RS02480	COG1366	Belongs to the anti-sigma-factor antagonist family
M2893_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
M2893_RS02490	COG2172	sigma factor antagonist activity
M2893_RS02495	COG2208	phosphoserine phosphatase activity
M2893_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
M2893_RS02510	COG1191	sigma factor activity
M2893_RS02515	COG2208	phosphoserine phosphatase activity
M2893_RS02520	COG2183	response to ionizing radiation
M2893_RS02575	COG2249	NAD(P)H dehydrogenase (quinone) activity
M2893_RS02595	COG0477	Major facilitator Superfamily
M2893_RS02605	COG1764	response to oxidative stress
M2893_RS02610	COG1846	Transcriptional regulator
M2893_RS02620	COG2030	dehydratase
M2893_RS02630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M2893_RS02635	COG1959	2 iron, 2 sulfur cluster binding
M2893_RS02640	COG2910	NAD(P)H-binding
M2893_RS02645	COG1278	Cold shock
M2893_RS02655	COG1937	Protein conserved in bacteria
M2893_RS02660	COG2210	Belongs to the sulfur carrier protein TusA family
M2893_RS02670	COG0425	Belongs to the sulfur carrier protein TusA family
M2893_RS02670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M2893_RS02680	COG0425	Belongs to the sulfur carrier protein TusA family
M2893_RS02685	COG0730	response to heat
M2893_RS02690	COG1794	racemase activity, acting on amino acids and derivatives
M2893_RS02705	COG3621	Patatin-like phospholipase
M2893_RS02730	COG0277	FAD linked oxidase domain protein
M2893_RS02765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M2893_RS02790	COG1064	alcohol dehydrogenase
M2893_RS02795	COG0789	Transcriptional regulator
M2893_RS02805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M2893_RS02820	COG2814	Major facilitator Superfamily
M2893_RS02825	COG1309	transcriptional regulator
M2893_RS02830	COG5577	PFAM Coat F domain
M2893_RS02840	COG1063	alcohol dehydrogenase
M2893_RS02845	COG5577	PFAM Coat F domain
M2893_RS02855	COG4585	Histidine kinase
M2893_RS02860	COG2197	response regulator
M2893_RS02865	COG2409	Drug exporters of the RND superfamily
M2893_RS02870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
M2893_RS02875	COG0488	(ABC) transporter
M2893_RS02880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M2893_RS02885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M2893_RS02895	COG2814	Major facilitator Superfamily
M2893_RS02900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M2893_RS02910	COG0730	response to heat
M2893_RS02915	COG0456	acetyltransferase
M2893_RS02920	COG0789	Transcriptional regulator
M2893_RS02920	COG4978	Transcriptional regulator
M2893_RS02925	COG0697	spore germination
M2893_RS02930	COG1051	belongs to the nudix hydrolase family
M2893_RS02935	COG2226	methyltransferase
M2893_RS02955	COG1802	Transcriptional regulator
M2893_RS02960	COG1819	glycosyl
M2893_RS02975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M2893_RS02985	COG1388	LysM domain
M2893_RS02990	COG2814	Major facilitator Superfamily
M2893_RS02995	COG2188	Transcriptional regulator
M2893_RS03000	COG2186	Transcriptional regulator
M2893_RS03005	COG2807	transmembrane transport
M2893_RS03010	COG2076	Multidrug Resistance protein
M2893_RS03015	COG2076	Multidrug Resistance protein
M2893_RS03020	COG1309	transcriptional regulator
M2893_RS03025	COG0531	amino acid
M2893_RS03035	COG3832	glyoxalase III activity
M2893_RS03040	COG0604	alcohol dehydrogenase
M2893_RS03045	COG2814	Major facilitator Superfamily
M2893_RS03085	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M2893_RS03090	COG0802	atpase or kinase
M2893_RS03095	COG1214	PFAM Peptidase M22, glycoprotease
M2893_RS03100	COG0456	acetyltransferase
M2893_RS03105	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
M2893_RS03110	COG0488	(ABC) transporter
M2893_RS03125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M2893_RS03130	COG0805	protein transport
M2893_RS03140	COG1266	CAAX protease self-immunity
M2893_RS03160	COG2856	Zn peptidase
M2893_RS03170	COG1396	sequence-specific DNA binding
M2893_RS03230	COG3935	DnaD domain protein
M2893_RS03235	COG1484	DNA-dependent DNA replication
M2893_RS03245	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
M2893_RS03310	COG1595	DNA-templated transcription, initiation
M2893_RS03335	COG5484	DNA packaging
M2893_RS03450	COG4824	toxin secretion phage lysis holin
M2893_RS03470	COG0457	Tetratricopeptide repeat
M2893_RS03475	COG1063	alcohol dehydrogenase
M2893_RS03480	COG2211	Major facilitator Superfamily
M2893_RS03485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M2893_RS03495	COG1842	Phage shock protein A
M2893_RS03500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M2893_RS03505	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M2893_RS03510	COG4260	virion core protein, lumpy skin disease virus
M2893_RS03515	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
M2893_RS03515	COG2755	lipolytic protein G-D-S-L family
M2893_RS03525	COG1595	DNA-templated transcription, initiation
M2893_RS03530	COG1063	alcohol dehydrogenase
M2893_RS03535	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M2893_RS03540	COG0823	Involved in the tonB-independent uptake of proteins
M2893_RS03555	COG2132	Multicopper oxidase
M2893_RS03560	COG1113	amino acid transport
M2893_RS03565	COG0714	Associated with various cellular activities
M2893_RS03570	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
M2893_RS03575	COG1305	Transglutaminase-like
M2893_RS03595	COG2252	PERMEase
M2893_RS03600	COG3064	Membrane
M2893_RS03620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M2893_RS03625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M2893_RS03630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M2893_RS03635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
M2893_RS03640	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M2893_RS03655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M2893_RS03665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M2893_RS03670	COG0138	bifunctional purine biosynthesis protein purh
M2893_RS03675	COG0151	Belongs to the GarS family
M2893_RS03685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M2893_RS03690	COG1470	cell adhesion involved in biofilm formation
M2893_RS03695	COG4496	protein, YerC YecD
M2893_RS03700	COG0069	glutamate synthase activity
M2893_RS03710	COG0210	DNA helicase
M2893_RS03720	COG4851	CamS sex pheromone cAM373 precursor
M2893_RS03725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M2893_RS03730	COG1285	pathogenesis
M2893_RS03735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M2893_RS03755	COG1309	transcriptional regulator
M2893_RS03760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M2893_RS03765	COG1597	lipid kinase activity
M2893_RS03770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M2893_RS03780	COG1131	(ABC) transporter
M2893_RS03820	COG5444	nuclease activity
M2893_RS03850	COG3546	catalase activity
M2893_RS03855	COG0454	-acetyltransferase
M2893_RS03865	COG2323	membrane
M2893_RS03870	COG2329	Antibiotic biosynthesis monooxygenase
M2893_RS03875	COG0346	lactoylglutathione lyase activity
M2893_RS03880	COG1366	Belongs to the anti-sigma-factor antagonist family
M2893_RS03885	COG5583	Uncharacterized small protein (DUF2292)
M2893_RS03890	COG0196	riboflavin kinase activity
M2893_RS03895	COG0670	Belongs to the BI1 family
M2893_RS03905	COG1846	Transcriptional regulator
M2893_RS03910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M2893_RS03920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M2893_RS03920	COG2124	cytochrome p450
M2893_RS03925	COG1368	sulfuric ester hydrolase activity
M2893_RS03930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M2893_RS03935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M2893_RS03940	COG1442	glycosyl transferase family 8
M2893_RS03945	COG1216	Glycosyl transferase, family 2
M2893_RS03950	COG1442	glycosyl transferase family 8
M2893_RS03955	COG2223	nitrite transmembrane transporter activity
M2893_RS03960	COG0531	amino acid
M2893_RS03965	COG1012	belongs to the aldehyde dehydrogenase family
M2893_RS03970	COG0840	transmembrane signaling receptor activity
M2893_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS03980	COG0457	Tetratricopeptide repeat
M2893_RS03980	COG0463	Glycosyl transferase, family 2
M2893_RS03985	COG0488	(ABC) transporter
M2893_RS03990	COG0789	Transcriptional regulator
M2893_RS03995	COG2814	Major facilitator Superfamily
M2893_RS04000	COG0488	(ABC) transporter
M2893_RS04005	COG0513	Belongs to the DEAD box helicase family
M2893_RS04015	COG2130	NADP-dependent
M2893_RS04030	COG3866	Pectate lyase
M2893_RS04035	COG0471	metal ion transport
M2893_RS04060	COG2972	Histidine kinase
M2893_RS04060	COG0745	RESPONSE REGULATOR receiver
M2893_RS04070	COG3279	Response regulator of the LytR AlgR family
M2893_RS04080	COG3764	Sortase (surface protein transpeptidase)
M2893_RS04085	COG3290	protein histidine kinase activity
M2893_RS04090	COG4565	transcriptional regulatory protein
M2893_RS04095	COG3181	Tripartite tricarboxylate transporter family receptor
M2893_RS04100	COG2851	Citrate transporter
M2893_RS04105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2893_RS04110	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
M2893_RS04120	COG2258	MOSC domain
M2893_RS04140	COG0024	Methionine aminopeptidase
M2893_RS04145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M2893_RS04145	COG1263	PTS System
M2893_RS04155	COG1368	sulfuric ester hydrolase activity
M2893_RS04165	COG0071	Belongs to the small heat shock protein (HSP20) family
M2893_RS04180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M2893_RS04180	COG1263	PTS System
M2893_RS04185	COG0366	Alpha amylase catalytic
M2893_RS04190	COG2188	Transcriptional regulator
M2893_RS04195	COG0778	Nitroreductase
M2893_RS04210	COG0737	Belongs to the 5'-nucleotidase family
M2893_RS04215	COG0693	protein deglycase activity
M2893_RS04220	COG1609	Transcriptional regulator
M2893_RS04235	COG2814	Major facilitator Superfamily
M2893_RS04250	COG4980	gas vesicle protein
M2893_RS04255	COG1295	ribonuclease BN
M2893_RS04260	COG0477	Major facilitator Superfamily
M2893_RS04265	COG0387	Pfam Sodium calcium exchanger
M2893_RS04275	COG0668	transmembrane transport
M2893_RS04280	COG0535	radical SAM domain protein
M2893_RS04290	COG0726	polysaccharide deacetylase
M2893_RS04295	COG2084	Dehydrogenase
M2893_RS04305	COG0598	Magnesium transport protein CorA
M2893_RS04310	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M2893_RS04315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M2893_RS04325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M2893_RS04330	COG4637	Psort location Cytoplasmic, score
M2893_RS04335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M2893_RS04340	COG0022	dehydrogenase e1 component
M2893_RS04345	COG0508	dehydrogenase complex catalyzes the overall conversion of
M2893_RS04350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M2893_RS04355	COG3284	Transcriptional regulator
M2893_RS04365	COG1486	melibiose metabolic process
M2893_RS04370	COG1737	Transcriptional regulator
M2893_RS04375	COG1263	PTS System
M2893_RS04375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M2893_RS04380	COG1132	(ABC) transporter
M2893_RS04385	COG1132	(ABC) transporter
M2893_RS04390	COG2259	Doxx family
M2893_RS04395	COG2514	catechol 2,3-dioxygenase activity
M2893_RS04405	COG1695	Transcriptional regulator
M2893_RS04410	COG2249	NAD(P)H dehydrogenase (quinone) activity
M2893_RS04415	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
M2893_RS04420	COG0574	Belongs to the PEP-utilizing enzyme family
M2893_RS04420	COG3848	Pyruvate phosphate dikinase
M2893_RS04425	COG2732	(Barnase) inhibitor
M2893_RS04435	COG2814	Major facilitator Superfamily
M2893_RS04440	COG1846	Transcriptional regulator
M2893_RS04445	COG0392	lysyltransferase activity
M2893_RS04445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
M2893_RS04450	COG0384	phenazine biosynthesis protein PhzF
M2893_RS04455	COG0778	Nitroreductase
M2893_RS04470	COG1090	epimerase
M2893_RS04485	COG2814	Major facilitator Superfamily
M2893_RS04495	COG3591	Belongs to the peptidase S1B family
M2893_RS04510	COG3103	Sh3 type 3 domain protein
M2893_RS04515	COG5658	integral membrane protein
M2893_RS04520	COG0596	Alpha beta hydrolase
M2893_RS04525	COG0463	Glycosyl transferase, family 2
M2893_RS04530	COG4485	Bacterial membrane protein, YfhO
M2893_RS04535	COG1988	membrane-bound metal-dependent
M2893_RS04540	COG1194	a g-specific adenine glycosylase
M2893_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS04570	COG1132	(ABC) transporter
M2893_RS04575	COG4129	membrane
M2893_RS04585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M2893_RS04590	COG0735	belongs to the Fur family
M2893_RS04705	COG3340	Belongs to the peptidase S51 family
M2893_RS04715	COG0277	FAD linked oxidase domain protein
M2893_RS04725	COG0747	negative chemotaxis
M2893_RS04730	COG0601	transmembrane transport
M2893_RS04735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M2893_RS04740	COG0444	Belongs to the ABC transporter superfamily
M2893_RS04745	COG4608	Belongs to the ABC transporter superfamily
M2893_RS04750	COG0753	catalase activity
M2893_RS04760	COG1116	anion transmembrane transporter activity
M2893_RS04765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M2893_RS04770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M2893_RS04790	COG1476	TRANSCRIPTIONal
M2893_RS04800	COG3382	B3 4 domain protein
M2893_RS04805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M2893_RS04815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M2893_RS04820	COG0789	Transcriptional regulator
M2893_RS04825	COG1664	Polymer-forming cytoskeletal
M2893_RS04830	COG1664	Polymer-forming cytoskeletal
M2893_RS04835	COG2766	serine protein kinase
M2893_RS04845	COG1846	Transcriptional regulator
M2893_RS04850	COG1566	PFAM secretion protein HlyD family protein
M2893_RS04855	COG2814	Major facilitator Superfamily
M2893_RS04860	COG0655	NAD(P)H dehydrogenase (quinone) activity
M2893_RS04875	COG1725	Transcriptional regulator
M2893_RS04880	COG1131	(ABC) transporter
M2893_RS04885	COG1131	(ABC) transporter
M2893_RS04890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M2893_RS04895	COG1278	Cold shock
M2893_RS04900	COG1464	Belongs to the NlpA lipoprotein family
M2893_RS04905	COG3706	GGDEF domain
M2893_RS04910	COG1823	symporter activity
M2893_RS04930	COG5577	PFAM Coat F domain
M2893_RS04935	COG4085	toxin activity
M2893_RS04935	COG0737	Belongs to the 5'-nucleotidase family
M2893_RS04935	COG1525	nuclease
M2893_RS04940	COG3764	Sortase (surface protein transpeptidase)
M2893_RS04945	COG0564	pseudouridine synthase activity
M2893_RS04955	COG0517	IMP dehydrogenase activity
M2893_RS04960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M2893_RS04965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M2893_RS04965	COG3153	acetyltransferase
M2893_RS04970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M2893_RS04975	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M2893_RS04980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M2893_RS04990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M2893_RS04995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M2893_RS05010	COG0431	NADPH-dependent FMN reductase
M2893_RS05025	COG0791	NLP P60 protein
M2893_RS05025	COG1388	LysM domain
M2893_RS05030	COG1959	2 iron, 2 sulfur cluster binding
M2893_RS05040	COG2719	SpoVR family
M2893_RS05045	COG1785	Belongs to the alkaline phosphatase family
M2893_RS05050	COG0791	NLP P60 protein
M2893_RS05050	COG1388	LysM domain
M2893_RS05055	COG0583	DNA-binding transcription factor activity
M2893_RS05060	COG0372	Belongs to the citrate synthase family
M2893_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS05070	COG0531	amino acid
M2893_RS05075	COG0733	neurotransmitter:sodium symporter activity
M2893_RS05090	COG1595	DNA-templated transcription, initiation
M2893_RS05095	COG0204	Acyl-transferase
M2893_RS05100	COG1253	flavin adenine dinucleotide binding
M2893_RS05105	COG0789	Transcriptional regulator
M2893_RS05110	COG0436	Aminotransferase
M2893_RS05115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M2893_RS05120	COG1253	flavin adenine dinucleotide binding
M2893_RS05125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M2893_RS05130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M2893_RS05135	COG0584	glycerophosphoryl diester phosphodiesterase
M2893_RS05145	COG0668	transmembrane transport
M2893_RS05150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M2893_RS05155	COG0726	polysaccharide deacetylase
M2893_RS05160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M2893_RS05165	COG3226	Transcriptional regulator
M2893_RS05175	COG0589	response to stress
M2893_RS05180	COG1132	(ABC) transporter
M2893_RS05185	COG1132	(ABC) transporter
M2893_RS05190	COG0702	epimerase
M2893_RS05210	COG0189	ligase activity
M2893_RS05215	COG0189	ligase activity
M2893_RS05230	COG4335	DNA alkylation repair
M2893_RS05235	COG0561	phosphatase activity
M2893_RS05240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M2893_RS05250	COG0475	glutathione-regulated potassium exporter activity
M2893_RS05255	COG0490	domain, Protein
M2893_RS05265	COG1024	Enoyl-CoA hydratase
M2893_RS05275	COG4152	abc transporter atp-binding protein
M2893_RS05280	COG1668	transmembrane transport
M2893_RS05285	COG0420	3'-5' exonuclease activity
M2893_RS05290	COG4717	serine-type aminopeptidase activity
M2893_RS05305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M2893_RS05340	COG4980	gas vesicle protein
M2893_RS05355	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
M2893_RS05360	COG0537	adenosine 5'-monophosphoramidase activity
M2893_RS05365	COG1131	(ABC) transporter
M2893_RS05370	COG4473	ABC transporter
M2893_RS05380	COG1473	amidohydrolase
M2893_RS05385	COG3069	C4-dicarboxylate transmembrane transporter activity
M2893_RS05390	COG2329	Antibiotic biosynthesis monooxygenase
M2893_RS05395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M2893_RS05405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M2893_RS05410	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M2893_RS05415	COG1309	transcriptional regulator
M2893_RS05420	COG1511	domain protein
M2893_RS05425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M2893_RS05435	COG1363	Peptidase, m42
M2893_RS05440	COG1301	dicarboxylic acid transport
M2893_RS05450	COG1234	tRNA 3'-trailer cleavage
M2893_RS05455	COG0095	Lipoate-protein ligase
M2893_RS05460	COG0702	epimerase
M2893_RS05465	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS05475	COG0501	Belongs to the peptidase M48B family
M2893_RS05480	COG1404	Belongs to the peptidase S8 family
M2893_RS05485	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M2893_RS05490	COG0406	alpha-ribazole phosphatase activity
M2893_RS05495	COG0183	Belongs to the thiolase family
M2893_RS05500	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS05505	COG1268	BioY protein
M2893_RS05510	COG0840	transmembrane signaling receptor activity
M2893_RS05515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M2893_RS05515	COG0723	plastoquinol--plastocyanin reductase activity
M2893_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS05530	COG4903	ComK protein
M2893_RS05540	COG5646	InterPro IPR014922
M2893_RS05560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M2893_RS05575	COG0398	Pfam SNARE associated Golgi protein
M2893_RS05580	COG0681	Belongs to the peptidase S26 family
M2893_RS05585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M2893_RS05590	COG1846	Transcriptional regulator
M2893_RS05595	COG3180	Ammonia monooxygenase
M2893_RS05600	COG2814	Major facilitator Superfamily
M2893_RS05610	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M2893_RS05615	COG2323	membrane
M2893_RS05630	COG0420	3'-5' exonuclease activity
M2893_RS05635	COG0419	ATPase involved in DNA repair
M2893_RS05640	COG1403	HNH endonuclease
M2893_RS05680	COG0179	Fumarylacetoacetate (FAA) hydrolase
M2893_RS05700	COG0367	asparagine synthase
M2893_RS05705	COG1562	ergosterol biosynthetic process
M2893_RS05710	COG0534	Mate efflux family protein
M2893_RS05715	COG2207	Transcriptional regulator
M2893_RS05715	COG1917	Cupin 2, conserved barrel domain protein
M2893_RS05720	COG1609	Transcriptional regulator
M2893_RS05725	COG0673	inositol 2-dehydrogenase activity
M2893_RS05730	COG2318	DinB family
M2893_RS05735	COG1357	PFAM Pentapeptide repeats (8 copies)
M2893_RS05740	COG2153	protein acetylation
M2893_RS05745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M2893_RS05745	COG0646	methionine synthase
M2893_RS05755	COG2996	Protein conserved in bacteria
M2893_RS05760	COG1744	ABC transporter substrate-binding protein PnrA-like
M2893_RS05775	COG1307	EDD domain protein, DegV family
M2893_RS05780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M2893_RS05800	COG0561	phosphatase activity
M2893_RS05805	COG1073	alpha beta
M2893_RS05810	COG2151	metal-sulfur cluster biosynthetic enzyme
M2893_RS05820	COG0277	FAD linked oxidase domain protein
M2893_RS05825	COG2271	Major facilitator Superfamily
M2893_RS05835	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M2893_RS05845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M2893_RS05850	COG0505	Belongs to the CarA family
M2893_RS05855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M2893_RS05860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
M2893_RS05875	COG2267	carboxylic ester hydrolase activity
M2893_RS05885	COG1744	ABC transporter substrate-binding protein PnrA-like
M2893_RS05900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M2893_RS05905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M2893_RS05910	COG5504	Zn-dependent protease
M2893_RS05915	COG0444	Belongs to the ABC transporter superfamily
M2893_RS05920	COG4608	Belongs to the ABC transporter superfamily
M2893_RS05930	COG0601	transmembrane transport
M2893_RS05935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M2893_RS05945	COG0180	Tryptophanyl-tRNA synthetase
M2893_RS05950	COG4166	transmembrane transport
M2893_RS05955	COG0601	transmembrane transport
M2893_RS05960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M2893_RS05965	COG0444	Belongs to the ABC transporter superfamily
M2893_RS05970	COG4608	Belongs to the ABC transporter superfamily
M2893_RS05980	COG0456	acetyltransferase
M2893_RS05985	COG1393	Belongs to the ArsC family
M2893_RS05990	COG0861	Integral membrane protein TerC family
M2893_RS06000	COG4862	establishment of competence for transformation
M2893_RS06005	COG4469	Competence protein
M2893_RS06010	COG1164	Oligoendopeptidase f
M2893_RS06020	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M2893_RS06025	COG2346	COG2346, Truncated hemoglobins
M2893_RS06030	COG0741	lytic transglycosylase activity
M2893_RS06035	COG4116	CYTH
M2893_RS06045	COG2357	RelA SpoT domain protein
M2893_RS06050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M2893_RS06055	COG0564	pseudouridine synthase activity
M2893_RS06065	COG0569	domain protein
M2893_RS06065	COG0475	glutathione-regulated potassium exporter activity
M2893_RS06070	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M2893_RS06075	COG0352	thiamine-phosphate diphosphorylase activity
M2893_RS06080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M2893_RS06085	COG2104	thiamine diphosphate biosynthetic process
M2893_RS06095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M2893_RS06100	COG0351	phosphomethylpyrimidine kinase
M2893_RS06105	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
M2893_RS06160	COG0210	DNA helicase
M2893_RS06180	COG1131	(ABC) transporter
M2893_RS06190	COG2153	protein acetylation
M2893_RS06200	COG2382	esterase
M2893_RS06205	COG0626	cystathionine gamma-synthase activity
M2893_RS06210	COG0626	cystathionine gamma-synthase activity
M2893_RS06235	COG5444	nuclease activity
M2893_RS06245	COG0346	lactoylglutathione lyase activity
M2893_RS06250	COG2367	Beta-lactamase
M2893_RS06255	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M2893_RS06265	COG1846	Transcriptional regulator
M2893_RS06275	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M2893_RS06280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M2893_RS06285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
M2893_RS06290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M2893_RS06290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M2893_RS06295	COG1447	Phosphotransferase system cellobiose-specific component IIA
M2893_RS06305	COG1349	DNA-binding transcription factor activity
M2893_RS06325	COG1285	pathogenesis
M2893_RS06335	COG2205	protein histidine kinase activity
M2893_RS06345	COG3383	formate dehydrogenase (NAD+) activity
M2893_RS06350	COG2427	Protein of unknown function (DUF1641)
M2893_RS06355	COG2124	cytochrome p450
M2893_RS06360	COG1819	glycosyl
M2893_RS06370	COG1587	Uroporphyrinogen-III synthase
M2893_RS06375	COG0390	transport system, permease component
M2893_RS06380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M2893_RS06385	COG0697	spore germination
M2893_RS06390	COG4297	protein containing double-stranded beta helix domain
M2893_RS06400	COG1252	NADH dehydrogenase
M2893_RS06410	COG2211	Major facilitator Superfamily
M2893_RS06415	COG1609	Transcriptional regulator
M2893_RS06425	COG2721	sulfolactate sulfo-lyase activity
M2893_RS06430	COG0745	RESPONSE REGULATOR receiver
M2893_RS06435	COG2770	Histidine kinase
M2893_RS06435	COG2205	protein histidine kinase activity
M2893_RS06455	COG4585	Histidine kinase
M2893_RS06460	COG2197	response regulator
M2893_RS06495	COG0730	response to heat
M2893_RS06500	COG2318	DinB family
M2893_RS06505	COG0457	Tetratricopeptide repeat
M2893_RS06515	COG1388	LysM domain
M2893_RS06515	COG3409	Peptidoglycan-binding domain 1 protein
M2893_RS06515	COG5632	N-Acetylmuramoyl-L-alanine amidase
M2893_RS06525	COG4195	phage-related replication protein
M2893_RS06535	COG2856	Zn peptidase
M2893_RS06540	COG1396	sequence-specific DNA binding
M2893_RS06550	COG1522	sequence-specific DNA binding
M2893_RS06555	COG1484	DNA-dependent DNA replication
M2893_RS06575	COG1595	DNA-templated transcription, initiation
M2893_RS06580	COG3728	DNA packaging
M2893_RS06580	COG5484	DNA packaging
M2893_RS06585	COG1783	phage Terminase large subunit
M2893_RS06590	COG5518	Phage portal protein
M2893_RS06595	COG0338	D12 class N6 adenine-specific DNA methyltransferase
M2893_RS06600	COG4653	Phage capsid family
M2893_RS06650	COG5412	phage tail tape measure protein
M2893_RS06650	COG3953	SLT domain
M2893_RS06650	COG5412	phage tail tape measure protein
M2893_RS06650	COG3953	SLT domain
M2893_RS06650	COG3953	SLT domain
M2893_RS06650	COG5412	phage tail tape measure protein
M2893_RS06655	COG1652	LysM domain
M2893_RS06660	COG4193	domain, Protein
M2893_RS06670	COG3628	GPW Gp25 family protein
M2893_RS06675	COG3299	homolog of phage Mu protein gp47
M2893_RS06680	COG3778	Protein conserved in bacteria
M2893_RS06720	COG3409	Peptidoglycan-binding domain 1 protein
M2893_RS06720	COG5632	N-Acetylmuramoyl-L-alanine amidase
M2893_RS06740	COG0306	phosphate transporter
M2893_RS06745	COG1392	Phosphate transport regulator
M2893_RS06750	COG0531	amino acid
M2893_RS06755	COG0346	lactoylglutathione lyase activity
M2893_RS06760	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
M2893_RS06765	COG0463	Glycosyl transferase, family 2
M2893_RS06770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M2893_RS06775	COG0477	Major facilitator Superfamily
M2893_RS06780	COG2362	D-Aminopeptidase
M2893_RS06785	COG0601	transmembrane transport
M2893_RS06790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M2893_RS06795	COG0444	Belongs to the ABC transporter superfamily
M2893_RS06800	COG4166	transmembrane transport
M2893_RS06805	COG1619	proteins homologs of microcin C7 resistance protein MccF
M2893_RS06810	COG4948	Mandelate Racemase Muconate Lactonizing
M2893_RS06815	COG0791	NLP P60 protein
M2893_RS06820	COG4608	Belongs to the ABC transporter superfamily
M2893_RS06825	COG2706	6-phosphogluconolactonase activity
M2893_RS06830	COG1834	amidinotransferase
M2893_RS06835	COG1607	acyl-coa hydrolase
M2893_RS06840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M2893_RS06845	COG2076	Multidrug Resistance protein
M2893_RS06850	COG2076	Multidrug Resistance protein
M2893_RS06855	COG0788	formyltetrahydrofolate deformylase activity
M2893_RS06860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M2893_RS06870	COG1764	response to oxidative stress
M2893_RS06875	COG1846	Transcriptional regulator
M2893_RS06880	COG1764	response to oxidative stress
M2893_RS06895	COG0463	Glycosyl transferase, family 2
M2893_RS06895	COG0457	Tetratricopeptide repeat
M2893_RS06905	COG2814	Major facilitator Superfamily
M2893_RS06910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M2893_RS06920	COG1404	Belongs to the peptidase S8 family
M2893_RS06925	COG1366	Belongs to the anti-sigma-factor antagonist family
M2893_RS06930	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M2893_RS06935	COG1122	ATPase activity
M2893_RS06940	COG4721	ABC-type cobalt transport system, permease component
M2893_RS06945	COG1388	LysM domain
M2893_RS06945	COG3858	chitin binding
M2893_RS06955	COG2239	Acts as a magnesium transporter
M2893_RS06960	COG0789	Transcriptional regulator
M2893_RS06975	COG1846	Transcriptional regulator
M2893_RS06980	COG0726	polysaccharide deacetylase
M2893_RS06985	COG3285	dna ligase
M2893_RS06985	COG1793	dna ligase
M2893_RS06990	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
M2893_RS06995	COG0586	Pfam SNARE associated Golgi protein
M2893_RS07005	COG1191	sigma factor activity
M2893_RS07030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M2893_RS07035	COG2323	membrane
M2893_RS07045	COG3594	Acyltransferase
M2893_RS07050	COG5002	protein histidine kinase activity
M2893_RS07055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M2893_RS07075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M2893_RS07080	COG0436	Aminotransferase
M2893_RS07110	COG3852	Histidine kinase
M2893_RS07115	COG1846	Transcriptional regulator
M2893_RS07120	COG1360	Flagellar Motor Protein
M2893_RS07125	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M2893_RS07130	COG0542	response to heat
M2893_RS07135	COG3949	Membrane
M2893_RS07150	COG0720	synthase
M2893_RS07155	COG0602	queuosine metabolic process
M2893_RS07170	COG4873	Protein conserved in bacteria
M2893_RS07180	COG3773	Cell wall hydrolase
M2893_RS07185	COG2244	polysaccharide biosynthetic process
M2893_RS07190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS07195	COG2217	Heavy metal translocating P-type atpase
M2893_RS07200	COG0006	proline dipeptidase activity
M2893_RS07205	COG1609	Transcriptional regulator
M2893_RS07210	COG3711	transcriptional antiterminator
M2893_RS07215	COG1263	PTS System
M2893_RS07215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M2893_RS07215	COG2190	(PTS) system
M2893_RS07220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M2893_RS07225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M2893_RS07235	COG1533	DNA photolyase activity
M2893_RS07240	COG0840	transmembrane signaling receptor activity
M2893_RS07245	COG2084	Dehydrogenase
M2893_RS07250	COG2340	Cysteine-rich secretory protein family
M2893_RS07255	COG0768	penicillin binding
M2893_RS07260	COG4191	Histidine kinase
M2893_RS07265	COG0436	Aminotransferase
M2893_RS07275	COG0784	Response regulator, receiver
M2893_RS07275	COG0835	chemotaxis
M2893_RS07285	COG2814	Major facilitator Superfamily
M2893_RS07290	COG1376	ErfK ybiS ycfS ynhG family protein
M2893_RS07295	COG1408	metallophosphoesterase
M2893_RS07300	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS07310	COG2200	EAL domain
M2893_RS07315	COG4703	Protein of unknown function (DUF1797)
M2893_RS07320	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
M2893_RS07330	COG0517	IMP dehydrogenase activity
M2893_RS07335	COG0583	DNA-binding transcription factor activity
M2893_RS07340	COG0716	FMN binding
M2893_RS07350	COG0716	FMN binding
M2893_RS07370	COG0668	transmembrane transport
M2893_RS07375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS07395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M2893_RS07400	COG0303	'Molybdopterin
M2893_RS07405	COG1763	Mo-molybdopterin cofactor biosynthetic process
M2893_RS07410	COG0314	molybdopterin synthase activity
M2893_RS07415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M2893_RS07425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M2893_RS07430	COG1136	(ABC) transporter
M2893_RS07435	COG0577	efflux transmembrane transporter activity
M2893_RS07440	COG1349	DNA-binding transcription factor activity
M2893_RS07445	COG1105	Belongs to the carbohydrate kinase PfkB family
M2893_RS07450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M2893_RS07450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M2893_RS07450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M2893_RS07455	COG0681	Belongs to the peptidase S26 family
M2893_RS07465	COG0488	(ABC) transporter
M2893_RS07470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M2893_RS07475	COG2309	aminopeptidase activity
M2893_RS07485	COG1077	Cell shape determining protein MreB Mrl
M2893_RS07490	COG2002	toxin-antitoxin pair type II binding
M2893_RS07495	COG3852	Histidine kinase
M2893_RS07500	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
M2893_RS07500	COG2105	PFAM AIG2 family protein
M2893_RS07505	COG0569	domain protein
M2893_RS07515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M2893_RS07525	COG0561	phosphatase activity
M2893_RS07530	COG0242	peptide deformylase activity
M2893_RS07540	COG0497	DNA recombination
M2893_RS07550	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS07550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS07550	COG3321	synthase
M2893_RS07550	COG4221	oxidoreductase activity
M2893_RS07555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS07555	COG4221	oxidoreductase activity
M2893_RS07555	COG0300	oxidoreductase activity
M2893_RS07555	COG3321	synthase
M2893_RS07560	COG3321	synthase
M2893_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS07560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS07560	COG4221	oxidoreductase activity
M2893_RS07565	COG3321	synthase
M2893_RS07565	COG0300	oxidoreductase activity
M2893_RS07565	COG4221	oxidoreductase activity
M2893_RS07565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS07570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS07570	COG0300	oxidoreductase activity
M2893_RS07570	COG3321	synthase
M2893_RS07570	COG4221	oxidoreductase activity
M2893_RS07575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS07575	COG0300	oxidoreductase activity
M2893_RS07575	COG3321	synthase
M2893_RS07575	COG4221	oxidoreductase activity
M2893_RS07580	COG3321	synthase
M2893_RS07580	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS07580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS07580	COG4221	oxidoreductase activity
M2893_RS07585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M2893_RS07590	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M2893_RS07595	COG0022	dehydrogenase e1 component
M2893_RS07600	COG0508	dehydrogenase complex catalyzes the overall conversion of
M2893_RS07605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M2893_RS07610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS07625	COG1982	Orn Lys Arg decarboxylase major
M2893_RS07645	COG0483	inositol monophosphate 1-phosphatase activity
M2893_RS07655	COG3227	Zinc metalloprotease (Elastase)
M2893_RS07660	COG1595	DNA-templated transcription, initiation
M2893_RS07680	COG1217	gtp-binding protein TYPA
M2893_RS07690	COG4896	Protein conserved in bacteria
M2893_RS07700	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
M2893_RS07705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M2893_RS07795	COG0457	Tetratricopeptide repeat
M2893_RS07810	COG2433	Pfam Transposase IS66
M2893_RS07820	COG1196	nuclear chromosome segregation
M2893_RS07820	COG0741	lytic transglycosylase activity
M2893_RS07820	COG0739	heme binding
M2893_RS07955	COG0772	Belongs to the SEDS family
M2893_RS07960	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
M2893_RS07975	COG2010	Cytochrome c
M2893_RS07975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M2893_RS07980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M2893_RS07985	COG1845	cytochrome c oxidase, subunit III
M2893_RS07990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M2893_RS07995	COG3336	cytochrome c oxidase
M2893_RS08005	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
M2893_RS08010	COG2340	Cysteine-rich secretory protein family
M2893_RS08025	COG3679	Belongs to the UPF0342 family
M2893_RS08040	COG0742	ribosomal rna small subunit methyltransferase
M2893_RS08050	COG3314	Sporulation integral membrane protein YlbJ
M2893_RS08055	COG1752	Esterase of the alpha-beta hydrolase superfamily
M2893_RS08060	COG3480	Lon protease (S16) C-terminal proteolytic domain
M2893_RS08070	COG1399	metal-binding, possibly nucleic acid-binding protein
M2893_RS08090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M2893_RS08110	COG4839	cell division protein FtsL
M2893_RS08115	COG0768	penicillin binding
M2893_RS08120	COG0768	penicillin binding
M2893_RS08140	COG0772	Belongs to the SEDS family
M2893_RS08155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M2893_RS08160	COG0849	cell division
M2893_RS08165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M2893_RS08170	COG1404	Belongs to the peptidase S8 family
M2893_RS08170	COG4412	M6 family metalloprotease domain protein
M2893_RS08180	COG1191	sigma factor activity
M2893_RS08185	COG1191	sigma factor activity
M2893_RS08190	COG1119	ATPase activity
M2893_RS08195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M2893_RS08200	COG1873	PFAM PRC-barrel domain
M2893_RS08205	COG1496	oxidoreductase activity
M2893_RS08210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M2893_RS08220	COG0762	integral membrane protein
M2893_RS08225	COG2302	S4 RNA-binding domain
M2893_RS08230	COG3599	regulation of cell shape
M2893_RS08235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M2893_RS08240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M2893_RS08250	COG0564	pseudouridine synthase activity
M2893_RS08260	COG2233	PERMEase
M2893_RS08270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
M2893_RS08275	COG0505	Belongs to the CarA family
M2893_RS08280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M2893_RS08295	COG0284	orotidine-5'-phosphate decarboxylase activity
M2893_RS08300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
M2893_RS08310	COG0306	phosphate transporter
M2893_RS08325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M2893_RS08330	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
M2893_RS08335	COG1648	precorrin-2 dehydrogenase activity
M2893_RS08345	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M2893_RS08350	COG1561	YicC-like family, N-terminal region
M2893_RS08360	COG0194	GDP metabolic process
M2893_RS08370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M2893_RS08375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M2893_RS08380	COG0242	peptide deformylase activity
M2893_RS08390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M2893_RS08390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M2893_RS08400	COG0631	protein serine/threonine phosphatase activity
M2893_RS08405	COG2815	serine threonine protein kinase
M2893_RS08405	COG0515	serine threonine protein kinase
M2893_RS08415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M2893_RS08420	COG1564	THIamine pyrophosphokinase
M2893_RS08435	COG1302	Protein conserved in bacteria
M2893_RS08440	COG1461	Dihydroxyacetone kinase
M2893_RS08445	COG1760	l-serine dehydratase
M2893_RS08450	COG1760	l-serine dehydratase
M2893_RS08455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M2893_RS08470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M2893_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS08490	COG1196	nuclear chromosome segregation
M2893_RS08495	COG0552	protein localization to endoplasmic reticulum
M2893_RS08510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M2893_RS08520	COG1837	Belongs to the UPF0109 family
M2893_RS08545	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M2893_RS08560	COG2257	FlhB HrpN YscU SpaS Family
M2893_RS08570	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M2893_RS08575	COG0758	DNA mediated transformation
M2893_RS08580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M2893_RS08590	COG4974	Belongs to the 'phage' integrase family
M2893_RS08610	COG1815	bacterial-type flagellum-dependent cell motility
M2893_RS08615	COG1558	bacterial-type flagellum-dependent cell motility
M2893_RS08620	COG1677	Flagellar hook-basal body complex protein FliE
M2893_RS08625	COG1766	The M ring may be actively involved in energy transduction
M2893_RS08630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M2893_RS08635	COG1317	bacterial-type flagellum organization
M2893_RS08640	COG1157	protein secretion by the type III secretion system
M2893_RS08645	COG2882	bacterial-type flagellum organization
M2893_RS08650	COG3334	PFAM MgtE intracellular
M2893_RS08655	COG3144	bacterial-type flagellum assembly
M2893_RS08660	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M2893_RS08665	COG4786	Flagellar basal body rod
M2893_RS08670	COG1582	Flagellar protein (FlbD)
M2893_RS08675	COG1580	Controls the rotational direction of flagella during chemotaxis
M2893_RS08680	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M2893_RS08685	COG1776	CheC inhibitor of MCP methylation
M2893_RS08685	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M2893_RS08690	COG2201	protein-glutamate methylesterase activity
M2893_RS08695	COG3190	flagellar
M2893_RS08700	COG1338	Plays a role in the flagellum-specific transport system
M2893_RS08705	COG1987	bacterial-type flagellum assembly
M2893_RS08710	COG1684	flagellar biosynthetic protein fliR
M2893_RS08715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M2893_RS08720	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M2893_RS08725	COG1419	protein localization to endoplasmic reticulum
M2893_RS08730	COG0455	bacterial-type flagellum organization
M2893_RS08735	COG2201	protein-glutamate methylesterase activity
M2893_RS08740	COG0643	Histidine kinase
M2893_RS08740	COG2198	Histidine kinase
M2893_RS08745	COG0835	chemotaxis
M2893_RS08750	COG1776	CheC inhibitor of MCP methylation
M2893_RS08760	COG1191	sigma factor activity
M2893_RS08790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M2893_RS08795	COG4589	Belongs to the CDS family
M2893_RS08805	COG0750	zinc metalloprotease
M2893_RS08825	COG0195	Participates in both transcription termination and antitermination
M2893_RS08830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M2893_RS08835	COG1358	cellular component organization or biogenesis
M2893_RS08845	COG1550	Protein conserved in bacteria
M2893_RS08860	COG0196	riboflavin kinase activity
M2893_RS08875	COG0726	polysaccharide deacetylase
M2893_RS08880	COG0612	Peptidase, M16
M2893_RS08885	COG1873	PFAM PRC-barrel domain
M2893_RS08890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M2893_RS08895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M2893_RS08900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M2893_RS08905	COG0527	aspartate kinase activity
M2893_RS08915	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M2893_RS08920	COG0740	serine-type endopeptidase activity
M2893_RS08930	COG1674	ftsk spoiiie
M2893_RS08930	COG4980	gas vesicle protein
M2893_RS08935	COG2188	Transcriptional regulator
M2893_RS08940	COG2814	Major facilitator Superfamily
M2893_RS08945	COG1846	Transcriptional regulator
M2893_RS08950	COG2409	Drug exporters of the RND superfamily
M2893_RS08950	COG1033	growth of symbiont in host cell
M2893_RS08955	COG0612	Peptidase, M16
M2893_RS08960	COG0612	Peptidase, M16
M2893_RS08965	COG0300	oxidoreductase activity
M2893_RS08980	COG1426	Protein conserved in bacteria
M2893_RS08985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M2893_RS09000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M2893_RS09010	COG1692	metallophosphoesterase
M2893_RS09015	COG2359	stage V sporulation protein S
M2893_RS09035	COG4550	Control of competence regulator ComK, YlbF/YmcA
M2893_RS09080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS09085	COG3425	synthase
M2893_RS09090	COG1024	Enoyl-CoA hydratase
M2893_RS09095	COG1024	Enoyl-CoA hydratase
M2893_RS09100	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS09100	COG3321	synthase
M2893_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS09100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS09100	COG0300	oxidoreductase activity
M2893_RS09105	COG0300	oxidoreductase activity
M2893_RS09105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS09105	COG4221	oxidoreductase activity
M2893_RS09105	COG3321	synthase
M2893_RS09110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS09110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M2893_RS09110	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS09110	COG3321	synthase
M2893_RS09110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS09110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M2893_RS09110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS09110	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS09110	COG3321	synthase
M2893_RS09110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS09115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS09115	COG3321	synthase
M2893_RS09115	COG4221	oxidoreductase activity
M2893_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS09120	COG3321	synthase
M2893_RS09120	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M2893_RS09120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS09120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M2893_RS09125	COG2124	cytochrome p450
M2893_RS09130	COG3209	COG3209 Rhs family protein
M2893_RS09135	COG3619	membrane
M2893_RS09145	COG1404	Belongs to the peptidase S8 family
M2893_RS09150	COG4195	phage-related replication protein
M2893_RS09155	COG1764	response to oxidative stress
M2893_RS09165	COG2076	Multidrug Resistance protein
M2893_RS09205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M2893_RS09210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M2893_RS09215	COG4112	unkown
M2893_RS09220	COG0860	N-Acetylmuramoyl-L-alanine amidase
M2893_RS09225	COG0464	growth
M2893_RS09230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M2893_RS09235	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
M2893_RS09240	COG0789	Transcriptional regulator
M2893_RS09245	COG0174	glutamine synthetase
M2893_RS09255	COG2211	Major facilitator Superfamily
M2893_RS09260	COG3507	Belongs to the glycosyl hydrolase 43 family
M2893_RS09275	COG1070	Carbohydrate kinase
M2893_RS09280	COG3848	Pyruvate phosphate dikinase
M2893_RS09280	COG0574	Belongs to the PEP-utilizing enzyme family
M2893_RS09300	COG1064	alcohol dehydrogenase
M2893_RS09320	COG0456	acetyltransferase
M2893_RS09340	COG3397	chitin binding
M2893_RS09360	COG5434	Belongs to the glycosyl hydrolase 28 family
M2893_RS09365	COG0756	dUTP diphosphatase activity
M2893_RS09370	COG4195	phage-related replication protein
M2893_RS09405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M2893_RS09415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M2893_RS09435	COG0785	Cytochrome C biogenesis protein
M2893_RS09440	COG2201	protein-glutamate methylesterase activity
M2893_RS09445	COG4846	Membrane protein involved in cytochrome C biogenesis
M2893_RS09455	COG0071	Belongs to the small heat shock protein (HSP20) family
M2893_RS09470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M2893_RS09475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS09495	COG0824	Thioesterase
M2893_RS09505	COG4841	protein insertion into membrane
M2893_RS09515	COG1832	CoA-binding protein
M2893_RS09520	COG0187	DNA topoisomerase II activity
M2893_RS09525	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M2893_RS09535	COG1115	amino acid carrier protein
M2893_RS09545	COG1063	alcohol dehydrogenase
M2893_RS09550	COG0800	Aldolase
M2893_RS09555	COG1312	Catalyzes the dehydration of D-mannonate
M2893_RS09560	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS09565	COG1609	Transcriptional regulator
M2893_RS09570	COG2271	Major facilitator Superfamily
M2893_RS09605	COG2205	protein histidine kinase activity
M2893_RS09610	COG0745	RESPONSE REGULATOR receiver
M2893_RS09620	COG3507	Belongs to the glycosyl hydrolase 43 family
M2893_RS09645	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS09650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M2893_RS09655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M2893_RS09660	COG2610	gluconate transmembrane transporter activity
M2893_RS09665	COG2124	cytochrome p450
M2893_RS09685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M2893_RS09695	COG2246	polysaccharide biosynthetic process
M2893_RS09700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M2893_RS09705	COG0586	Pfam SNARE associated Golgi protein
M2893_RS09710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M2893_RS09715	COG1024	Enoyl-CoA hydratase
M2893_RS09720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M2893_RS09725	COG0511	ligase activity, forming carbon-carbon bonds
M2893_RS09730	COG0439	Biotin carboxylase
M2893_RS09735	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS09740	COG1960	acyl-CoA dehydrogenase activity
M2893_RS09745	COG1649	PFAM Uncharacterised BCR, COG1649
M2893_RS09755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS09755	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M2893_RS09760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS09765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS09770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS09775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS09780	COG2027	D-alanyl-D-alanine carboxypeptidase
M2893_RS09785	COG2017	converts alpha-aldose to the beta-anomer
M2893_RS09790	COG0534	Mate efflux family protein
M2893_RS09805	COG0582	viral genome integration into host DNA
M2893_RS09810	COG0166	Belongs to the GPI family
M2893_RS09815	COG0405	Gamma-glutamyltransferase
M2893_RS09820	COG2814	Major facilitator Superfamily
M2893_RS09825	COG0640	Transcriptional regulator
M2893_RS09840	COG0604	alcohol dehydrogenase
M2893_RS09845	COG0493	'glutamate synthase
M2893_RS09850	COG0067	glutamate synthase
M2893_RS09850	COG0070	glutamate synthase
M2893_RS09850	COG0069	glutamate synthase activity
M2893_RS09855	COG0583	DNA-binding transcription factor activity
M2893_RS09860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M2893_RS09875	COG0300	oxidoreductase activity
M2893_RS09880	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
M2893_RS09890	COG2814	Major facilitator Superfamily
M2893_RS09895	COG1070	Carbohydrate kinase
M2893_RS09900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M2893_RS09905	COG0243	molybdopterin cofactor binding
M2893_RS09920	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS09925	COG1733	regulation of RNA biosynthetic process
M2893_RS09930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M2893_RS09935	COG0662	Cupin 2, conserved barrel domain protein
M2893_RS09935	COG2207	Transcriptional regulator
M2893_RS09940	COG1309	transcriptional regulator
M2893_RS09945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2893_RS09955	COG0640	Transcriptional regulator
M2893_RS09960	COG0741	lytic transglycosylase activity
M2893_RS09965	COG2322	membrane
M2893_RS09980	COG1619	proteins homologs of microcin C7 resistance protein MccF
M2893_RS09990	COG1388	LysM domain
M2893_RS09990	COG3584	3D domain protein
M2893_RS09995	COG0514	ATP-dependent DNA helicase (RecQ)
M2893_RS10005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M2893_RS10010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M2893_RS10025	COG0071	Belongs to the small heat shock protein (HSP20) family
M2893_RS10055	COG1012	belongs to the aldehyde dehydrogenase family
M2893_RS10060	COG1657	PFAM Prenyltransferase squalene oxidase
M2893_RS10065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M2893_RS10070	COG0733	neurotransmitter:sodium symporter activity
M2893_RS10075	COG0385	Bile acid
M2893_RS10080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2893_RS10085	COG0508	dehydrogenase complex catalyzes the overall conversion of
M2893_RS10095	COG4548	von Willebrand factor, type A
M2893_RS10100	COG0714	Associated with various cellular activities
M2893_RS10105	COG2032	superoxide dismutase activity
M2893_RS10110	COG1388	LysM domain
M2893_RS10110	COG0791	NLP P60 protein
M2893_RS10115	COG1819	glycosyl
M2893_RS10120	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M2893_RS10125	COG0534	Mate efflux family protein
M2893_RS10130	COG1366	Belongs to the anti-sigma-factor antagonist family
M2893_RS10135	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M2893_RS10140	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M2893_RS10150	COG2962	Rard protein
M2893_RS10165	COG1942	4-Oxalocrotonate Tautomerase
M2893_RS10175	COG1733	regulation of RNA biosynthetic process
M2893_RS10180	COG0778	Nitroreductase
M2893_RS10185	COG0400	carboxylic ester hydrolase activity
M2893_RS10190	COG0346	lactoylglutathione lyase activity
M2893_RS10200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M2893_RS10210	COG2723	6-phospho-beta-galactosidase activity
M2893_RS10215	COG2188	Transcriptional regulator
M2893_RS10220	COG3409	Peptidoglycan-binding domain 1 protein
M2893_RS10220	COG0793	Belongs to the peptidase S41A family
M2893_RS10225	COG2226	methyltransferase
M2893_RS10235	COG1876	peptidase activity
M2893_RS10255	COG0671	phosphoesterase, PA-phosphatase related
M2893_RS10290	COG1509	lysine 2,3-aminomutase activity
M2893_RS10295	COG0456	acetyltransferase
M2893_RS10300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M2893_RS10305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M2893_RS10310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M2893_RS10315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M2893_RS10320	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
M2893_RS10330	COG0456	acetyltransferase
M2893_RS10335	COG0463	Glycosyl transferase, family 2
M2893_RS10350	COG4641	Protein conserved in bacteria
M2893_RS10360	COG1086	Polysaccharide biosynthesis protein
M2893_RS10405	COG1388	LysM domain
M2893_RS10410	COG0457	Tetratricopeptide repeat
M2893_RS10420	COG3391	amine dehydrogenase activity
M2893_RS10465	COG5444	nuclease activity
M2893_RS10505	COG1846	Transcriptional regulator
M2893_RS10510	COG4698	Protein conserved in bacteria
M2893_RS10515	COG2755	lipolytic protein G-D-S-L family
M2893_RS10520	COG1999	signal sequence binding
M2893_RS10530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M2893_RS10535	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M2893_RS10540	COG1272	protein, Hemolysin III
M2893_RS10545	COG0204	Acyl-transferase
M2893_RS10550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M2893_RS10565	COG2136	Putative SAM-dependent methyltransferase
M2893_RS10565	COG2521	methyltransferase
M2893_RS10580	COG1413	lyase activity
M2893_RS10585	COG1418	mRNA catabolic process
M2893_RS10590	COG0386	Belongs to the glutathione peroxidase family
M2893_RS10600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M2893_RS10610	COG1278	Cold shock
M2893_RS10630	COG0328	RNA-DNA hybrid ribonuclease activity
M2893_RS10635	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
M2893_RS10640	COG0328	RNA-DNA hybrid ribonuclease activity
M2893_RS10650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M2893_RS10665	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M2893_RS10675	COG1755	Isoprenylcysteine carboxyl methyltransferase
M2893_RS10680	COG3424	synthase
M2893_RS10705	COG1335	isochorismatase
M2893_RS10720	COG3331	DNA recombination
M2893_RS10755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M2893_RS10790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M2893_RS10795	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
M2893_RS10820	COG4112	unkown
M2893_RS10825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS10830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M2893_RS10840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M2893_RS10840	COG1372	Participates in initiation and elongation during chromosome replication
M2893_RS10845	COG1780	Probably involved in ribonucleotide reductase function
M2893_RS10950	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
M2893_RS10955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
M2893_RS10970	COG3584	3D domain protein
M2893_RS11025	COG3420	alginic acid biosynthetic process
M2893_RS11025	COG5434	Belongs to the glycosyl hydrolase 28 family
M2893_RS11030	COG4195	phage-related replication protein
M2893_RS11070	COG2135	peptidase activity
M2893_RS11075	COG1793	dna ligase
M2893_RS11085	COG0756	dUTP diphosphatase activity
M2893_RS11125	COG4474	Belongs to the UPF0398 family
M2893_RS11175	COG3655	Transcriptional regulator
M2893_RS11285	COG3655	Transcriptional regulator
M2893_RS11380	COG0776	regulation of translation
M2893_RS11515	COG1196	nuclear chromosome segregation
M2893_RS11515	COG0741	lytic transglycosylase activity
M2893_RS11515	COG0739	heme binding
M2893_RS11535	COG5434	Belongs to the glycosyl hydrolase 28 family
M2893_RS11540	COG3409	Peptidoglycan-binding domain 1 protein
M2893_RS11540	COG5632	N-Acetylmuramoyl-L-alanine amidase
M2893_RS11560	COG0457	Tetratricopeptide repeat
M2893_RS11565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M2893_RS11595	COG5444	nuclease activity
M2893_RS11605	COG4282	regulation of fungal-type cell wall biogenesis
M2893_RS11610	COG1525	nuclease
M2893_RS11630	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M2893_RS11635	COG1199	ATP-dependent helicase activity
M2893_RS11650	COG0116	Belongs to the methyltransferase superfamily
M2893_RS11680	COG3359	exonuclease
M2893_RS11685	COG1205	dead DEAH box helicase
M2893_RS11685	COG1111	helicase
M2893_RS11690	COG2190	(PTS) system
M2893_RS11695	COG0071	Belongs to the small heat shock protein (HSP20) family
M2893_RS11735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M2893_RS11735	COG4499	WXG100 protein secretion system (Wss), protein YukC
M2893_RS11745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M2893_RS11750	COG3935	DnaD domain protein
M2893_RS11760	COG0436	Aminotransferase
M2893_RS11765	COG5353	protein conserved in bacteria
M2893_RS11775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M2893_RS11775	COG1199	ATP-dependent helicase activity
M2893_RS11805	COG0438	transferase activity, transferring glycosyl groups
M2893_RS11810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M2893_RS11825	COG1694	Mazg nucleotide pyrophosphohydrolase
M2893_RS11830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M2893_RS11835	COG2140	Oxalate decarboxylase
M2893_RS11845	COG4347	Protein of unknown function (DUF1405)
M2893_RS11850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M2893_RS11850	COG2010	Cytochrome c
M2893_RS11855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M2893_RS11860	COG0723	plastoquinol--plastocyanin reductase activity
M2893_RS11875	COG0457	Tetratricopeptide repeat
M2893_RS11885	COG0287	Prephenate dehydrogenase
M2893_RS11920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M2893_RS11925	COG4401	Chorismate mutase type I
M2893_RS11940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M2893_RS11945	COG0105	UTP biosynthetic process
M2893_RS11950	COG0142	geranyltranstransferase activity
M2893_RS11960	COG0142	geranyltranstransferase activity
M2893_RS11975	COG0776	regulation of translation
M2893_RS11980	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M2893_RS12020	COG0539	negative regulation of cytoplasmic translation
M2893_RS12035	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
M2893_RS12040	COG2959	enzyme of heme biosynthesis
M2893_RS12045	COG3409	Peptidoglycan-binding domain 1 protein
M2893_RS12045	COG3773	Cell wall hydrolase
M2893_RS12050	COG2339	peptidase activity
M2893_RS12055	COG0492	ferredoxin-NADP+ reductase activity
M2893_RS12060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M2893_RS12065	COG4862	establishment of competence for transformation
M2893_RS12070	COG1408	metallophosphoesterase
M2893_RS12080	COG1388	LysM domain
M2893_RS12085	COG1266	CAAX protease self-immunity
M2893_RS12090	COG0514	ATP-dependent DNA helicase (RecQ)
M2893_RS12095	COG4955	Helix-turn-helix domain
M2893_RS12100	COG1141	Ferredoxin
M2893_RS12105	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M2893_RS12110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M2893_RS12120	COG1595	DNA-templated transcription, initiation
M2893_RS12125	COG5002	protein histidine kinase activity
M2893_RS12130	COG0745	RESPONSE REGULATOR receiver
M2893_RS12135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M2893_RS12140	COG1333	cytochrome c biogenesis protein
M2893_RS12145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS12150	COG1187	pseudouridine synthase activity
M2893_RS12155	COG0700	Nucleoside recognition
M2893_RS12160	COG2715	membrane protein required for spore maturation
M2893_RS12165	COG1686	Belongs to the peptidase S11 family
M2893_RS12190	COG1547	Domain of unknown function (DUF309)
M2893_RS12195	COG0456	acetyltransferase
M2893_RS12210	COG0307	riboflavin synthase, alpha
M2893_RS12215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M2893_RS12215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M2893_RS12225	COG0681	Belongs to the peptidase S26 family
M2893_RS12235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M2893_RS12240	COG4086	secreted protein
M2893_RS12245	COG0019	diaminopimelate decarboxylase activity
M2893_RS12250	COG0697	spore germination
M2893_RS12265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M2893_RS12285	COG1191	sigma factor activity
M2893_RS12295	COG1366	Belongs to the anti-sigma-factor antagonist family
M2893_RS12300	COG1686	Belongs to the peptidase S11 family
M2893_RS12305	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
M2893_RS12310	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
M2893_RS12315	COG4974	Belongs to the 'phage' integrase family
M2893_RS12325	COG0735	belongs to the Fur family
M2893_RS12330	COG1300	Membrane
M2893_RS12345	COG0281	malic enzyme
M2893_RS12350	COG1757	Na H antiporter
M2893_RS12355	COG1027	Aspartate ammonia-lyase
M2893_RS12360	COG0252	asparaginase activity
M2893_RS12365	COG1396	sequence-specific DNA binding
M2893_RS12370	COG1379	DNA repair
M2893_RS12375	COG0494	nUDIX hydrolase
M2893_RS12385	COG0667	Aldo Keto reductase
M2893_RS12405	COG4918	Iron-sulphur cluster biosynthesis
M2893_RS12410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M2893_RS12410	COG0456	acetyltransferase
M2893_RS12415	COG2329	Antibiotic biosynthesis monooxygenase
M2893_RS12420	COG0456	acetyltransferase
M2893_RS12425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M2893_RS12440	COG0628	permease
M2893_RS12450	COG0346	lactoylglutathione lyase activity
M2893_RS12460	COG3048	D-serine ammonia-lyase activity
M2893_RS12465	COG0300	oxidoreductase activity
M2893_RS12470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2893_RS12475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M2893_RS12480	COG1024	Enoyl-CoA hydratase
M2893_RS12485	COG3425	synthase
M2893_RS12490	COG2124	cytochrome p450
M2893_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS12495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS12495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M2893_RS12495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS12495	COG3321	synthase
M2893_RS12500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M2893_RS12500	COG3321	synthase
M2893_RS12500	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS12500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS12500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS12505	COG3321	synthase
M2893_RS12505	COG0300	oxidoreductase activity
M2893_RS12505	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS12505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS12505	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS12510	COG3321	synthase
M2893_RS12510	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS12510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS12510	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS12510	COG0300	oxidoreductase activity
M2893_RS12515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M2893_RS12515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS12515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS12515	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS12515	COG3321	synthase
M2893_RS12520	COG3321	synthase
M2893_RS12520	COG0300	oxidoreductase activity
M2893_RS12520	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS12520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS12525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2893_RS12525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS12525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M2893_RS12525	COG3321	synthase
M2893_RS12530	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS12535	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS12550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M2893_RS12550	COG2070	2-Nitropropane dioxygenase
M2893_RS12555	COG0250	Participates in transcription elongation, termination and antitermination
M2893_RS12575	COG0596	Alpha beta hydrolase
M2893_RS12590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M2893_RS12595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M2893_RS12610	COG0706	membrane insertase activity
M2893_RS12615	COG2195	Cleaves the N-terminal amino acid of tripeptides
M2893_RS12620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M2893_RS12625	COG0346	lactoylglutathione lyase activity
M2893_RS12635	COG1376	ErfK ybiS ycfS ynhG family protein
M2893_RS12640	COG4129	membrane
M2893_RS12645	COG1126	abc transporter atp-binding protein
M2893_RS12650	COG0765	amino acid transport
M2893_RS12655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M2893_RS12665	COG1597	lipid kinase activity
M2893_RS12670	COG0508	dehydrogenase complex catalyzes the overall conversion of
M2893_RS12675	COG0022	dehydrogenase e1 component
M2893_RS12680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M2893_RS12685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M2893_RS12690	COG3426	butyrate kinase activity
M2893_RS12695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M2893_RS12700	COG0280	phosphate acetyltransferase
M2893_RS12705	COG3290	protein histidine kinase activity
M2893_RS12705	COG3829	transcription factor binding
M2893_RS12715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
M2893_RS12720	COG2079	MmgE PrpD family protein
M2893_RS12725	COG0372	Belongs to the citrate synthase family
M2893_RS12730	COG1960	acyl-CoA dehydrogenase activity
M2893_RS12735	COG1250	3-hydroxyacyl-CoA dehydrogenase
M2893_RS12740	COG0183	Belongs to the thiolase family
M2893_RS12745	COG0584	glycerophosphoryl diester phosphodiesterase
M2893_RS12750	COG0860	N-Acetylmuramoyl-L-alanine amidase
M2893_RS12775	COG1902	pentaerythritol trinitrate reductase activity
M2893_RS12790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M2893_RS12795	COG0745	RESPONSE REGULATOR receiver
M2893_RS12800	COG0750	zinc metalloprotease
M2893_RS12805	COG0497	DNA recombination
M2893_RS12815	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M2893_RS12825	COG0142	geranyltranstransferase activity
M2893_RS12835	COG1570	exodeoxyribonuclease VII activity
M2893_RS12850	COG1302	Protein conserved in bacteria
M2893_RS12855	COG0439	Biotin carboxylase
M2893_RS12860	COG0511	ligase activity, forming carbon-carbon bonds
M2893_RS12900	COG3854	ATPases associated with a variety of cellular activities
M2893_RS12915	COG0006	proline dipeptidase activity
M2893_RS12925	COG3872	metal-dependent enzyme
M2893_RS12935	COG1752	Esterase of the alpha-beta hydrolase superfamily
M2893_RS12950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M2893_RS12970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M2893_RS12985	COG1396	sequence-specific DNA binding
M2893_RS12995	COG0681	Belongs to the peptidase S26 family
M2893_RS13020	COG4940	Competence protein ComGF
M2893_RS13030	COG4970	Tfp pilus assembly protein FimT
M2893_RS13035	COG4537	Required for transformation and DNA binding
M2893_RS13040	COG1459	type II secretion system
M2893_RS13045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M2893_RS13050	COG0598	Magnesium transport protein CorA
M2893_RS13055	COG1253	flavin adenine dinucleotide binding
M2893_RS13060	COG1366	Belongs to the anti-sigma-factor antagonist family
M2893_RS13070	COG1393	Belongs to the ArsC family
M2893_RS13080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2893_RS13090	COG0011	TIGRFAM Protein of
M2893_RS13100	COG2866	Carboxypeptidase
M2893_RS13105	COG1940	carbohydrate kinase activity
M2893_RS13110	COG4483	Protein conserved in bacteria
M2893_RS13115	COG1757	Na H antiporter
M2893_RS13125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M2893_RS13140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M2893_RS13145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M2893_RS13150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M2893_RS13155	COG0581	inorganic phosphate transmembrane transporter activity
M2893_RS13160	COG0573	inorganic phosphate transmembrane transporter activity
M2893_RS13165	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M2893_RS13170	COG0768	penicillin binding
M2893_RS13175	COG0477	Major facilitator Superfamily
M2893_RS13180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M2893_RS13185	COG2839	Protein conserved in bacteria
M2893_RS13190	COG5521	maltodextrose utilization protein MalA
M2893_RS13195	COG1388	LysM domain
M2893_RS13205	COG4709	membrane
M2893_RS13210	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
M2893_RS13215	COG0735	belongs to the Fur family
M2893_RS13220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M2893_RS13235	COG0513	Belongs to the DEAD box helicase family
M2893_RS13250	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M2893_RS13255	COG2384	SAM-dependent methyltransferase
M2893_RS13260	COG2010	Cytochrome c
M2893_RS13265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M2893_RS13270	COG0358	DNA primase activity
M2893_RS13285	COG0517	IMP dehydrogenase activity
M2893_RS13290	COG0751	glycine-tRNA ligase activity
M2893_RS13310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M2893_RS13315	COG0295	cytidine deaminase activity
M2893_RS13320	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M2893_RS13330	COG1480	7TM receptor with intracellular HD hydrolase
M2893_RS13335	COG1702	phosphate starvation-inducible protein PhoH
M2893_RS13340	COG0561	phosphatase activity
M2893_RS13355	COG4864	UPF0365 protein
M2893_RS13360	COG1030	water channel activity
M2893_RS13365	COG1610	YqeY-like protein
M2893_RS13375	COG1283	sodium-dependent phosphate transmembrane transporter activity
M2893_RS13380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M2893_RS13385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M2893_RS13415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M2893_RS13430	COG0860	N-Acetylmuramoyl-L-alanine amidase
M2893_RS13460	COG0658	competence protein
M2893_RS13460	COG2333	competence protein COMEC
M2893_RS13465	COG2131	deaminase
M2893_RS13470	COG1555	photosystem II stabilization
M2893_RS13470	COG1596	polysaccharide export
M2893_RS13475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M2893_RS13480	COG2226	methyltransferase
M2893_RS13485	COG0799	negative regulation of ribosome biogenesis
M2893_RS13490	COG1713	HD superfamily hydrolase involved in NAD metabolism
M2893_RS13500	COG1534	Rna-binding protein
M2893_RS13505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M2893_RS13510	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M2893_RS13515	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M2893_RS13525	COG2755	lipolytic protein G-D-S-L family
M2893_RS13535	COG0398	Pfam SNARE associated Golgi protein
M2893_RS13560	COG3708	Transcriptional regulator
M2893_RS13560	COG2207	Transcriptional regulator
M2893_RS13565	COG0563	adenylate kinase activity
M2893_RS13575	COG2814	Major facilitator Superfamily
M2893_RS13580	COG0456	acetyltransferase
M2893_RS13585	COG2318	DinB family
M2893_RS13595	COG0561	phosphatase activity
M2893_RS13600	COG0561	phosphatase activity
M2893_RS13610	COG1482	cell wall glycoprotein biosynthetic process
M2893_RS13615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M2893_RS13615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M2893_RS13615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M2893_RS13620	COG3711	transcriptional antiterminator
M2893_RS13620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M2893_RS13630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M2893_RS13635	COG0583	DNA-binding transcription factor activity
M2893_RS13640	COG2814	Major facilitator Superfamily
M2893_RS13645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M2893_RS13645	COG2124	cytochrome p450
M2893_RS13650	COG1309	transcriptional regulator
M2893_RS13655	COG2226	methyltransferase
M2893_RS13670	COG2116	formate transmembrane transporter activity
M2893_RS13675	COG5609	conserved protein (DUF2294)
M2893_RS13680	COG3383	formate dehydrogenase (NAD+) activity
M2893_RS13685	COG2427	Protein of unknown function (DUF1641)
M2893_RS13695	COG0626	cystathionine gamma-synthase activity
M2893_RS13700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M2893_RS13725	COG0768	penicillin binding
M2893_RS13740	COG0826	peptidase U32
M2893_RS13745	COG0826	peptidase U32
M2893_RS13750	COG4122	O-methyltransferase activity
M2893_RS13755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M2893_RS13770	COG4472	Bacterial protein of unknown function (DUF965)
M2893_RS13780	COG0628	permease
M2893_RS13785	COG1126	abc transporter atp-binding protein
M2893_RS13790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M2893_RS13795	COG0765	amino acid transport
M2893_RS13800	COG0765	amino acid transport
M2893_RS13815	COG3881	PFAM PRC-barrel domain
M2893_RS13820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M2893_RS13825	COG0457	Tetratricopeptide repeat
M2893_RS13835	COG1104	cysteine desulfurase activity
M2893_RS13840	COG1959	2 iron, 2 sulfur cluster binding
M2893_RS13845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M2893_RS13850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M2893_RS13875	COG0860	N-Acetylmuramoyl-L-alanine amidase
M2893_RS13875	COG4991	sh3 domain protein
M2893_RS13875	COG3103	Sh3 type 3 domain protein
M2893_RS13885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M2893_RS13895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M2893_RS13895	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M2893_RS13900	COG5416	Lipopolysaccharide assembly protein A domain
M2893_RS13905	COG0490	domain, Protein
M2893_RS13910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M2893_RS13910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M2893_RS13920	COG2244	polysaccharide biosynthetic process
M2893_RS13925	COG2323	membrane
M2893_RS13935	COG1862	Preprotein translocase
M2893_RS13975	COG1388	LysM domain
M2893_RS13985	COG0157	Belongs to the NadC ModD family
M2893_RS13990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M2893_RS13995	COG1104	cysteine desulfurase activity
M2893_RS14000	COG1827	regulation of RNA biosynthetic process
M2893_RS14005	COG0077	Prephenate dehydratase
M2893_RS14020	COG3290	protein histidine kinase activity
M2893_RS14025	COG0211	Belongs to the bacterial ribosomal protein bL27 family
M2893_RS14030	COG2868	ribosomal protein
M2893_RS14040	COG1994	Peptidase M50
M2893_RS14045	COG0739	heme binding
M2893_RS14050	COG2894	cell division
M2893_RS14060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M2893_RS14070	COG1077	Cell shape determining protein MreB Mrl
M2893_RS14090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M2893_RS14095	COG0285	dihydrofolate synthase activity
M2893_RS14100	COG0525	valine-tRNA ligase activity
M2893_RS14110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M2893_RS14115	COG1388	LysM domain
M2893_RS14125	COG0113	porphobilinogen synthase activity
M2893_RS14130	COG1587	Uroporphyrinogen-III synthase
M2893_RS14140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M2893_RS14160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M2893_RS14165	COG0470	DNA polymerase III
M2893_RS14165	COG1067	ATP-dependent peptidase activity
M2893_RS14180	COG0457	Tetratricopeptide repeat
M2893_RS14180	COG1477	protein flavinylation
M2893_RS14195	COG0473	3-isopropylmalate dehydrogenase activity
M2893_RS14210	COG0440	acetolactate synthase activity
M2893_RS14215	COG0028	Belongs to the TPP enzyme family
M2893_RS14240	COG0622	Phosphoesterase
M2893_RS14245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M2893_RS14255	COG5401	PFAM Sporulation and spore germination
M2893_RS14265	COG1846	Transcriptional regulator
M2893_RS14275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M2893_RS14280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M2893_RS14305	COG0457	Tetratricopeptide repeat
M2893_RS14400	COG5280	Phage tail tape measure protein TP901
M2893_RS14400	COG3953	SLT domain
M2893_RS14470	COG5484	DNA packaging
M2893_RS14480	COG3677	Transposase
M2893_RS14580	COG1484	DNA-dependent DNA replication
M2893_RS14585	COG3935	DnaD domain protein
M2893_RS14590	COG3723	Recombinational DNA repair protein, rece pathway
M2893_RS14595	COG5377	YqaJ viral recombinase family
M2893_RS14620	COG3645	SOS response
M2893_RS14620	COG3646	Phage regulatory protein
M2893_RS14645	COG3620	sequence-specific DNA binding
M2893_RS14650	COG1525	nuclease
M2893_RS14660	COG2856	Zn peptidase
M2893_RS14665	COG2197	response regulator
M2893_RS14670	COG0824	Thioesterase
M2893_RS14675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M2893_RS14680	COG1053	succinate dehydrogenase
M2893_RS14685	COG2009	succinate dehydrogenase
M2893_RS14690	COG1719	4-vinyl reductase, 4VR
M2893_RS14695	COG0527	aspartate kinase activity
M2893_RS14705	COG3118	belongs to the thioredoxin family
M2893_RS14710	COG3534	alpha-L-arabinofuranosidase
M2893_RS14715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M2893_RS14720	COG2086	electron transfer activity
M2893_RS14725	COG1024	Enoyl-CoA hydratase
M2893_RS14730	COG1309	transcriptional regulator
M2893_RS14735	COG0318	PFAM AMP-dependent synthetase and ligase
M2893_RS14745	COG3766	membrane
M2893_RS14755	COG1796	DNA polymerase
M2893_RS14755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M2893_RS14760	COG1286	toxin biosynthetic process
M2893_RS14775	COG0072	phenylalanine-tRNA ligase activity
M2893_RS14775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M2893_RS14780	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
M2893_RS14785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M2893_RS14795	COG3835	regulator
M2893_RS14800	COG0277	FAD linked oxidase domain protein
M2893_RS14805	COG0247	lactate metabolic process
M2893_RS14810	COG1966	Carbon starvation protein
M2893_RS14815	COG3534	alpha-L-arabinofuranosidase
M2893_RS14820	COG0395	ABC-type sugar transport system, permease component
M2893_RS14825	COG1175	transmembrane transport
M2893_RS14830	COG1653	transport
M2893_RS14840	COG0647	UMP catabolic process
M2893_RS14845	COG0235	Class ii aldolase
M2893_RS14850	COG1069	ribulokinase activity
M2893_RS14855	COG2160	L-arabinose isomerase activity
M2893_RS14860	COG3507	Belongs to the glycosyl hydrolase 43 family
M2893_RS14865	COG1363	Peptidase, m42
M2893_RS14875	COG3326	Membrane
M2893_RS14880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
M2893_RS14890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
M2893_RS14895	COG1346	cytolysis
M2893_RS14900	COG1380	Effector of murein hydrolase LrgA
M2893_RS14905	COG3279	Response regulator of the LytR AlgR family
M2893_RS14910	COG3275	phosphorelay sensor kinase activity
M2893_RS14915	COG1011	Hydrolase
M2893_RS14930	COG0398	Pfam SNARE associated Golgi protein
M2893_RS14935	COG1484	DNA-dependent DNA replication
M2893_RS14940	COG3611	Membrane attachment protein
M2893_RS14955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M2893_RS14960	COG1733	regulation of RNA biosynthetic process
M2893_RS14965	COG2814	Major facilitator Superfamily
M2893_RS14970	COG0656	L-ascorbic acid biosynthetic process
M2893_RS14975	COG0237	dephospho-CoA kinase activity
M2893_RS14980	COG1971	Probably functions as a manganese efflux pump
M2893_RS14985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
M2893_RS14990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M2893_RS14990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M2893_RS14995	COG5002	protein histidine kinase activity
M2893_RS15000	COG0745	RESPONSE REGULATOR receiver
M2893_RS15010	COG0538	isocitrate dehydrogenase activity
M2893_RS15015	COG0372	Belongs to the citrate synthase family
M2893_RS15035	COG0628	permease
M2893_RS15040	COG3030	protein affecting phage T7 exclusion by the F plasmid
M2893_RS15045	COG0469	pyruvate kinase activity
M2893_RS15065	COG0281	malic enzyme
M2893_RS15070	COG0587	DNA-directed DNA polymerase activity
M2893_RS15090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M2893_RS15100	COG4109	DRTGG domain
M2893_RS15110	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS15125	COG0521	Mo-molybdopterin cofactor biosynthetic process
M2893_RS15135	COG0827	DNA restriction-modification system
M2893_RS15140	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M2893_RS15145	COG3874	Sporulation protein YtfJ
M2893_RS15155	COG1714	RDD family
M2893_RS15160	COG0616	signal peptide processing
M2893_RS15165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M2893_RS15170	COG1574	metal-dependent hydrolase with the TIM-barrel fold
M2893_RS15175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M2893_RS15190	COG1104	cysteine desulfurase activity
M2893_RS15195	COG1114	Component of the transport system for branched-chain amino acids
M2893_RS15205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M2893_RS15210	COG1309	transcriptional regulator
M2893_RS15215	COG1956	GAF domain-containing protein
M2893_RS15220	COG2199	diguanylate cyclase activity
M2893_RS15220	COG2203	Gaf domain
M2893_RS15230	COG1012	belongs to the aldehyde dehydrogenase family
M2893_RS15235	COG4282	regulation of fungal-type cell wall biogenesis
M2893_RS15240	COG1017	nitric oxide dioxygenase activity
M2893_RS15240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M2893_RS15250	COG0693	protein deglycase activity
M2893_RS15265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M2893_RS15270	COG1378	Sugar-specific transcriptional regulator TrmB
M2893_RS15290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M2893_RS15295	COG0454	-acetyltransferase
M2893_RS15300	COG0517	IMP dehydrogenase activity
M2893_RS15305	COG0123	including yeast histone deacetylase and acetoin utilization protein
M2893_RS15310	COG1360	Flagellar Motor Protein
M2893_RS15315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M2893_RS15320	COG1609	Transcriptional regulator
M2893_RS15325	COG1605	Chorismate mutase
M2893_RS15325	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M2893_RS15330	COG3118	belongs to the thioredoxin family
M2893_RS15335	COG4980	gas vesicle protein
M2893_RS15340	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
M2893_RS15350	COG1674	ftsk spoiiie
M2893_RS15355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M2893_RS15365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS15375	COG1363	Peptidase, m42
M2893_RS15380	COG5584	Small secreted protein
M2893_RS15385	COG0281	malic enzyme
M2893_RS15390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2893_RS15405	COG0510	thiamine kinase activity
M2893_RS15410	COG1597	lipid kinase activity
M2893_RS15420	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M2893_RS15425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M2893_RS15430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M2893_RS15435	COG2252	PERMEase
M2893_RS15440	COG4473	ABC transporter
M2893_RS15445	COG1131	(ABC) transporter
M2893_RS15450	COG1349	DNA-binding transcription factor activity
M2893_RS15455	COG1187	pseudouridine synthase activity
M2893_RS15460	COG2244	polysaccharide biosynthetic process
M2893_RS15465	COG2081	HI0933 family
M2893_RS15470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M2893_RS15480	COG1609	Transcriptional regulator
M2893_RS15485	COG1653	transport
M2893_RS15490	COG1175	transmembrane transport
M2893_RS15495	COG0395	ABC-type sugar transport system, permease component
M2893_RS15500	COG1486	melibiose metabolic process
M2893_RS15510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M2893_RS15525	COG1366	Belongs to the anti-sigma-factor antagonist family
M2893_RS15525	COG2202	Pas domain
M2893_RS15530	COG2814	Major facilitator Superfamily
M2893_RS15535	COG5522	Integral membrane protein (intg_mem_TP0381)
M2893_RS15540	COG0577	efflux transmembrane transporter activity
M2893_RS15545	COG1136	(ABC) transporter
M2893_RS15550	COG2205	protein histidine kinase activity
M2893_RS15555	COG0745	RESPONSE REGULATOR receiver
M2893_RS15560	COG0577	efflux transmembrane transporter activity
M2893_RS15565	COG1136	(ABC) transporter
M2893_RS15585	COG1131	(ABC) transporter
M2893_RS15590	COG1725	Transcriptional regulator
M2893_RS15605	COG0640	Transcriptional regulator
M2893_RS15610	COG0477	Major facilitator Superfamily
M2893_RS15615	COG1242	4 iron, 4 sulfur cluster binding
M2893_RS15620	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M2893_RS15630	COG0584	glycerophosphoryl diester phosphodiesterase
M2893_RS15640	COG2267	carboxylic ester hydrolase activity
M2893_RS15645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M2893_RS15650	COG1113	amino acid transport
M2893_RS15655	COG0367	asparagine synthase
M2893_RS15675	COG1506	peptidase
M2893_RS15680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M2893_RS15685	COG1116	anion transmembrane transporter activity
M2893_RS15690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M2893_RS15695	COG0494	nUDIX hydrolase
M2893_RS15700	COG4824	toxin secretion phage lysis holin
M2893_RS15705	COG0783	Belongs to the Dps family
M2893_RS15730	COG0288	reversible hydration of carbon dioxide
M2893_RS15740	COG1271	oxidase subunit
M2893_RS15745	COG1294	oxidase, subunit
M2893_RS15755	COG4948	Mandelate Racemase Muconate Lactonizing
M2893_RS15765	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M2893_RS15770	COG0596	Alpha beta hydrolase
M2893_RS15780	COG1169	isochorismate synthase
M2893_RS15785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M2893_RS15790	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
M2893_RS15915	COG3859	Proton-coupled thiamine transporter YuaJ
M2893_RS15920	COG2268	Band 7 protein
M2893_RS15925	COG1585	Membrane protein implicated in regulation of membrane protease activity
M2893_RS15930	COG2318	DinB family
M2893_RS15940	COG1454	alcohol dehydrogenase
M2893_RS15945	COG1012	belongs to the aldehyde dehydrogenase family
M2893_RS15950	COG1510	regulation of RNA biosynthetic process
M2893_RS15960	COG0569	domain protein
M2893_RS15965	COG1705	Flagellar rod assembly protein muramidase FlgJ
M2893_RS15970	COG1017	nitric oxide dioxygenase activity
M2893_RS15970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M2893_RS15995	COG0628	permease
M2893_RS16000	COG0673	inositol 2-dehydrogenase activity
M2893_RS16005	COG0693	protein deglycase activity
M2893_RS16010	COG0840	transmembrane signaling receptor activity
M2893_RS16015	COG0840	transmembrane signaling receptor activity
M2893_RS16020	COG0840	transmembrane signaling receptor activity
M2893_RS16025	COG0840	transmembrane signaling receptor activity
M2893_RS16040	COG2070	2-Nitropropane dioxygenase
M2893_RS16045	COG0432	Pfam Uncharacterised protein family UPF0047
M2893_RS16050	COG0366	Alpha amylase catalytic
M2893_RS16055	COG1253	flavin adenine dinucleotide binding
M2893_RS16060	COG2738	Putative neutral zinc metallopeptidase
M2893_RS16075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M2893_RS16100	COG1335	isochorismatase
M2893_RS16105	COG1979	alcohol dehydrogenase
M2893_RS16110	COG1979	alcohol dehydrogenase
M2893_RS16115	COG2155	Conserved Protein
M2893_RS16120	COG1098	S1 RNA binding domain
M2893_RS16125	COG0436	Aminotransferase
M2893_RS16130	COG1522	sequence-specific DNA binding
M2893_RS16135	COG2267	carboxylic ester hydrolase activity
M2893_RS16145	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M2893_RS16150	COG2205	protein histidine kinase activity
M2893_RS16160	COG5018	Exonuclease
M2893_RS16165	COG2814	Major facilitator Superfamily
M2893_RS16170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M2893_RS16175	COG3011	Protein conserved in bacteria
M2893_RS16185	COG3290	protein histidine kinase activity
M2893_RS16190	COG4565	transcriptional regulatory protein
M2893_RS16195	COG1744	ABC transporter substrate-binding protein PnrA-like
M2893_RS16200	COG3845	ABC transporter
M2893_RS16205	COG4603	Belongs to the binding-protein-dependent transport system permease family
M2893_RS16210	COG1079	Belongs to the binding-protein-dependent transport system permease family
M2893_RS16220	COG2111	Na H antiporter
M2893_RS16220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M2893_RS16225	COG2111	Na H antiporter
M2893_RS16230	COG1006	Multisubunit Na H antiporter MnhC subunit
M2893_RS16235	COG0651	ATP synthesis coupled electron transport
M2893_RS16240	COG1863	multisubunit Na H antiporter MnhE subunit
M2893_RS16245	COG2212	antiporter activity
M2893_RS16250	COG1320	monovalent cation:proton antiporter activity
M2893_RS16255	COG2050	protein possibly involved in aromatic compounds catabolism
M2893_RS16260	COG2197	response regulator
M2893_RS16265	COG4585	Histidine kinase
M2893_RS16275	COG0142	geranyltranstransferase activity
M2893_RS16290	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
M2893_RS16295	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M2893_RS16300	COG1335	isochorismatase
M2893_RS16305	COG5506	Protein of unknown function (DUF1694)
M2893_RS16320	COG0628	permease
M2893_RS16330	COG1418	mRNA catabolic process
M2893_RS16335	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS16345	COG1511	domain protein
M2893_RS16350	COG1674	ftsk spoiiie
M2893_RS16350	COG0433	COG0433 Predicted ATPase
M2893_RS16355	COG4499	WXG100 protein secretion system (Wss), protein YukC
M2893_RS16360	COG5417	Belongs to the EsaB family
M2893_RS16365	COG4842	Belongs to the WXG100 family
M2893_RS16370	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M2893_RS16370	COG2508	Transcriptional regulator
M2893_RS16375	COG0686	Belongs to the AlaDH PNT family
M2893_RS16380	COG5634	Uncharacterized conserved protein (DUF2278)
M2893_RS16385	COG3251	PFAM MbtH domain protein
M2893_RS16390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2893_RS16395	COG1535	isochorismatase
M2893_RS16395	COG3433	isochorismatase activity
M2893_RS16400	COG1021	2,3-dihydroxybenzoate-AMP ligase
M2893_RS16405	COG1169	isochorismate synthase
M2893_RS16410	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS16415	COG2819	hydrolase of the alpha beta superfamily
M2893_RS16420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M2893_RS16425	COG1268	BioY protein
M2893_RS16430	COG2056	Na+-H+ antiporter family
M2893_RS16440	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
M2893_RS16445	COG3584	3D domain protein
M2893_RS16460	COG1252	NADH dehydrogenase
M2893_RS16490	COG1131	(ABC) transporter
M2893_RS16515	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
M2893_RS16520	COG0316	Belongs to the HesB IscA family
M2893_RS16530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M2893_RS16540	COG1252	NADH dehydrogenase
M2893_RS16545	COG4837	Protein of unknown function (DUF1462)
M2893_RS16550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
M2893_RS16555	COG1506	peptidase
M2893_RS16555	COG4946	Tricorn protease homolog
M2893_RS16555	COG0823	Involved in the tonB-independent uptake of proteins
M2893_RS16565	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M2893_RS16570	COG0460	homoserine dehydrogenase
M2893_RS16575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M2893_RS16580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M2893_RS16585	COG0647	UMP catabolic process
M2893_RS16590	COG2445	Protein of unknown function DUF86
M2893_RS16595	COG4470	Protein conserved in bacteria
M2893_RS16605	COG0739	heme binding
M2893_RS16615	COG0737	Belongs to the 5'-nucleotidase family
M2893_RS16620	COG0730	response to heat
M2893_RS16625	COG1801	Protein of unknown function DUF72
M2893_RS16640	COG2508	Transcriptional regulator
M2893_RS16665	COG2814	Major facilitator Superfamily
M2893_RS16670	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M2893_RS16675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M2893_RS16680	COG2356	endonuclease I
M2893_RS16685	COG3842	ATPase activity
M2893_RS16690	COG2188	Transcriptional regulator
M2893_RS16695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M2893_RS16700	COG0395	ABC-type sugar transport system, permease component
M2893_RS16705	COG1175	transmembrane transport
M2893_RS16710	COG1653	transport
M2893_RS16715	COG2222	sugar isomerase
M2893_RS16720	COG0789	Transcriptional regulator
M2893_RS16730	COG0322	excinuclease ABC activity
M2893_RS16735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M2893_RS16745	COG3409	Peptidoglycan-binding domain 1 protein
M2893_RS16750	COG0719	Fe-S assembly protein
M2893_RS16755	COG0822	iron-sulfur transferase activity
M2893_RS16760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M2893_RS16765	COG0719	Fe-S assembly protein
M2893_RS16770	COG0396	ATPase activity
M2893_RS16780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M2893_RS16785	COG1464	Belongs to the NlpA lipoprotein family
M2893_RS16790	COG2011	ABC-type metal ion transport system permease component
M2893_RS16795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M2893_RS16805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M2893_RS16810	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M2893_RS16825	COG1393	Belongs to the ArsC family
M2893_RS16830	COG1960	acyl-CoA dehydrogenase activity
M2893_RS16835	COG0183	Belongs to the thiolase family
M2893_RS16840	COG1024	Enoyl-CoA hydratase
M2893_RS16840	COG1250	3-hydroxyacyl-CoA dehydrogenase
M2893_RS16855	COG0477	Major facilitator Superfamily
M2893_RS16865	COG5577	PFAM Coat F domain
M2893_RS16870	COG1846	Transcriptional regulator
M2893_RS16875	COG0477	Major facilitator Superfamily
M2893_RS16880	COG0583	DNA-binding transcription factor activity
M2893_RS16900	COG1120	ATPase activity
M2893_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS16920	COG0783	Belongs to the Dps family
M2893_RS16925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M2893_RS16930	COG0745	RESPONSE REGULATOR receiver
M2893_RS16935	COG2770	Histidine kinase
M2893_RS16935	COG2205	protein histidine kinase activity
M2893_RS16945	COG1309	transcriptional regulator
M2893_RS16950	COG0114	fumarate hydratase activity
M2893_RS16960	COG0697	spore germination
M2893_RS16965	COG0814	amino acid
M2893_RS16975	COG2197	response regulator
M2893_RS16980	COG4585	Histidine kinase
M2893_RS16985	COG4758	membrane
M2893_RS16990	COG3595	metallopeptidase activity
M2893_RS16995	COG1842	Phage shock protein A
M2893_RS17000	COG4758	membrane
M2893_RS17005	COG2814	Major facilitator Superfamily
M2893_RS17010	COG2096	Adenosyltransferase
M2893_RS17015	COG1120	ATPase activity
M2893_RS17020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2893_RS17025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M2893_RS17030	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS17035	COG3386	PFAM SMP-30 Gluconolaconase
M2893_RS17040	COG2205	protein histidine kinase activity
M2893_RS17045	COG0745	RESPONSE REGULATOR receiver
M2893_RS17055	COG1191	sigma factor activity
M2893_RS17065	COG2140	Oxalate decarboxylase
M2893_RS17075	COG1120	ATPase activity
M2893_RS17080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2893_RS17085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2893_RS17090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M2893_RS17095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
M2893_RS17100	COG0531	amino acid
M2893_RS17110	COG1988	membrane-bound metal-dependent
M2893_RS17115	COG1368	sulfuric ester hydrolase activity
M2893_RS17120	COG1910	domain protein
M2893_RS17125	COG0725	ABC transporter, periplasmic molybdate-binding protein
M2893_RS17130	COG4149	molybdate abc transporter
M2893_RS17135	COG2197	response regulator
M2893_RS17140	COG3850	Histidine kinase
M2893_RS17145	COG1131	(ABC) transporter
M2893_RS17155	COG0842	Transport permease protein
M2893_RS17160	COG0656	L-ascorbic acid biosynthetic process
M2893_RS17180	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M2893_RS17185	COG3973	AAA domain
M2893_RS17190	COG2860	membrane
M2893_RS17200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
M2893_RS17205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M2893_RS17210	COG2217	Heavy metal translocating P-type atpase
M2893_RS17215	COG2217	Heavy metal translocating P-type atpase
M2893_RS17220	COG2608	mercury ion transmembrane transporter activity
M2893_RS17225	COG1937	Protein conserved in bacteria
M2893_RS17230	COG0673	inositol 2-dehydrogenase activity
M2893_RS17240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M2893_RS17245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M2893_RS17250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M2893_RS17255	COG1126	abc transporter atp-binding protein
M2893_RS17260	COG0765	amino acid transport
M2893_RS17265	COG0765	amino acid transport
M2893_RS17270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M2893_RS17275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M2893_RS17280	COG0454	-acetyltransferase
M2893_RS17285	COG0583	DNA-binding transcription factor activity
M2893_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS17295	COG2732	(Barnase) inhibitor
M2893_RS17310	COG0557	exoribonuclease II activity
M2893_RS17315	COG1647	Serine aminopeptidase, S33
M2893_RS17320	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M2893_RS17325	COG1476	TRANSCRIPTIONal
M2893_RS17330	COG1396	sequence-specific DNA binding
M2893_RS17335	COG1396	sequence-specific DNA binding
M2893_RS17340	COG1733	regulation of RNA biosynthetic process
M2893_RS17365	COG1131	(ABC) transporter
M2893_RS17370	COG1174	glycine betaine transport
M2893_RS17375	COG1732	Glycine betaine
M2893_RS17380	COG1174	glycine betaine transport
M2893_RS17385	COG0517	IMP dehydrogenase activity
M2893_RS17385	COG1125	glycine betaine transport
M2893_RS17390	COG1510	regulation of RNA biosynthetic process
M2893_RS17395	COG1174	glycine betaine transport
M2893_RS17400	COG1732	Glycine betaine
M2893_RS17405	COG1174	glycine betaine transport
M2893_RS17410	COG1125	glycine betaine transport
M2893_RS17410	COG0517	IMP dehydrogenase activity
M2893_RS17415	COG1510	regulation of RNA biosynthetic process
M2893_RS17420	COG2095	MarC family integral membrane protein
M2893_RS17425	COG3064	Membrane
M2893_RS17430	COG4640	response to antibiotic
M2893_RS17435	COG0456	acetyltransferase
M2893_RS17450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M2893_RS17465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M2893_RS17470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M2893_RS17475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M2893_RS17485	COG2234	aminopeptidase activity
M2893_RS17505	COG0126	phosphoglycerate kinase activity
M2893_RS17510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M2893_RS17515	COG2390	Transcriptional regulator
M2893_RS17520	COG2814	Major facilitator Superfamily
M2893_RS17525	COG1609	Transcriptional regulator
M2893_RS17530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M2893_RS17540	COG0583	DNA-binding transcription factor activity
M2893_RS17545	COG0697	spore germination
M2893_RS17550	COG1113	amino acid transport
M2893_RS17555	COG1737	Transcriptional regulator
M2893_RS17560	COG1070	Carbohydrate kinase
M2893_RS17585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M2893_RS17590	COG2186	Transcriptional regulator
M2893_RS17595	COG1620	l-lactate permease
M2893_RS17600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M2893_RS17610	COG5039	Polysaccharide pyruvyl transferase
M2893_RS17615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M2893_RS17620	COG0110	maltose O-acetyltransferase activity
M2893_RS17625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M2893_RS17630	COG2244	polysaccharide biosynthetic process
M2893_RS17635	COG1216	Glycosyl transferase, family 2
M2893_RS17640	COG5039	Polysaccharide pyruvyl transferase
M2893_RS17645	COG1216	Glycosyl transferase, family 2
M2893_RS17655	COG0438	transferase activity, transferring glycosyl groups
M2893_RS17660	COG1215	transferase activity, transferring glycosyl groups
M2893_RS17665	COG0438	transferase activity, transferring glycosyl groups
M2893_RS17670	COG1086	Polysaccharide biosynthesis protein
M2893_RS17675	COG0489	protein tyrosine kinase activity
M2893_RS17680	COG3944	biosynthesis protein
M2893_RS17685	COG1396	sequence-specific DNA binding
M2893_RS17690	COG2272	Belongs to the type-B carboxylesterase lipase family
M2893_RS17700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M2893_RS17705	COG2364	Membrane
M2893_RS17710	COG0456	acetyltransferase
M2893_RS17715	COG3479	Phenolic acid decarboxylase
M2893_RS17775	COG2223	nitrite transmembrane transporter activity
M2893_RS17780	COG1609	Transcriptional regulator
M2893_RS17790	COG0583	DNA-binding transcription factor activity
M2893_RS17795	COG2828	Protein conserved in bacteria
M2893_RS17800	COG0477	Major facilitator Superfamily
M2893_RS17800	COG2814	Major facilitator Superfamily
M2893_RS17805	COG1611	Belongs to the LOG family
M2893_RS17810	COG1694	Mazg nucleotide pyrophosphohydrolase
M2893_RS17815	COG0659	secondary active sulfate transmembrane transporter activity
M2893_RS17820	COG0288	reversible hydration of carbon dioxide
M2893_RS17825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M2893_RS17830	COG4290	ribonuclease
M2893_RS17835	COG2162	N-hydroxyarylamine O-acetyltransferase activity
M2893_RS17840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M2893_RS17850	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M2893_RS17860	COG1051	belongs to the nudix hydrolase family
M2893_RS17865	COG0492	ferredoxin-NADP+ reductase activity
M2893_RS17870	COG3883	PFAM NLP P60 protein
M2893_RS17870	COG0791	NLP P60 protein
M2893_RS17875	COG0457	Tetratricopeptide repeat
M2893_RS17880	COG5002	protein histidine kinase activity
M2893_RS17885	COG0745	RESPONSE REGULATOR receiver
M2893_RS17895	COG1132	(ABC) transporter
M2893_RS17900	COG0140	phosphoribosyl-ATP diphosphatase activity
M2893_RS17900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M2893_RS17925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M2893_RS17940	COG4990	cell redox homeostasis
M2893_RS17945	COG0110	maltose O-acetyltransferase activity
M2893_RS17965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M2893_RS17975	COG2188	Transcriptional regulator
M2893_RS17980	COG1309	transcriptional regulator
M2893_RS17985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M2893_RS17990	COG1950	PFAM Membrane protein of
M2893_RS17995	COG1983	PspC domain protein
M2893_RS18000	COG3595	metallopeptidase activity
M2893_RS18015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M2893_RS18025	COG4897	Protein conserved in bacteria
M2893_RS18030	COG3848	Pyruvate phosphate dikinase
M2893_RS18030	COG0574	Belongs to the PEP-utilizing enzyme family
M2893_RS18035	COG1309	transcriptional regulator
M2893_RS18040	COG2814	Major facilitator Superfamily
M2893_RS18050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M2893_RS18060	COG3409	Peptidoglycan-binding domain 1 protein
M2893_RS18060	COG0793	Belongs to the peptidase S41A family
M2893_RS18065	COG3420	alginic acid biosynthetic process
M2893_RS18070	COG2177	Part of the ABC transporter FtsEX involved in
M2893_RS18075	COG2884	Cell division ATP-binding protein ftsE
M2893_RS18080	COG2010	Cytochrome c
M2893_RS18085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M2893_RS18100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M2893_RS18115	COG1516	flagellar protein fliS
M2893_RS18120	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
M2893_RS18125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M2893_RS18145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M2893_RS18150	COG4786	Flagellar basal body rod
M2893_RS18150	COG1256	bacterial-type flagellum assembly
M2893_RS18155	COG3418	PFAM FlgN family protein
M2893_RS18160	COG2747	anti-sigma28 factor FlgM
M2893_RS18170	COG1040	competence protein
M2893_RS18180	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M2893_RS18185	COG1307	EDD domain protein, DegV family
M2893_RS18190	COG2197	response regulator
M2893_RS18195	COG4585	Histidine kinase
M2893_RS18200	COG1739	Uncharacterized protein family UPF0029
M2893_RS18205	COG1316	TRANSCRIPTIONal
M2893_RS18210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M2893_RS18215	COG0438	transferase activity, transferring glycosyl groups
M2893_RS18220	COG1215	transferase activity, transferring glycosyl groups
M2893_RS18225	COG3206	protein involved in exopolysaccharide biosynthesis
M2893_RS18230	COG3307	-O-antigen
M2893_RS18235	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M2893_RS18240	COG0438	transferase activity, transferring glycosyl groups
M2893_RS18240	COG0297	glycogen (starch) synthase activity
M2893_RS18245	COG2244	polysaccharide biosynthetic process
M2893_RS18255	COG2247	cell wall binding repeat
M2893_RS18255	COG0860	N-Acetylmuramoyl-L-alanine amidase
M2893_RS18260	COG2247	cell wall binding repeat
M2893_RS18260	COG2385	sporulation resulting in formation of a cellular spore
M2893_RS18270	COG1316	TRANSCRIPTIONal
M2893_RS18275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M2893_RS18280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M2893_RS18285	COG1134	teichoic acid transport
M2893_RS18290	COG1682	transport, permease protein
M2893_RS18295	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M2893_RS18305	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
M2893_RS18310	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
M2893_RS18315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M2893_RS18320	COG4193	domain, Protein
M2893_RS18325	COG1482	cell wall glycoprotein biosynthetic process
M2893_RS18330	COG0697	spore germination
M2893_RS18335	COG0814	amino acid
M2893_RS18345	COG1215	transferase activity, transferring glycosyl groups
M2893_RS18350	COG2814	Major facilitator Superfamily
M2893_RS18355	COG1316	TRANSCRIPTIONal
M2893_RS18360	COG0561	phosphatase activity
M2893_RS18365	COG2433	Pfam Transposase IS66
M2893_RS18370	COG0791	NLP P60 protein
M2893_RS18380	COG2843	Capsule synthesis protein
M2893_RS18390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M2893_RS18395	COG0697	spore germination
M2893_RS18400	COG0814	amino acid
M2893_RS18410	COG1609	Transcriptional regulator
M2893_RS18415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M2893_RS18425	COG1129	ABC transporter
M2893_RS18430	COG1172	Belongs to the binding-protein-dependent transport system permease family
M2893_RS18435	COG1879	ABC-type sugar transport system periplasmic component
M2893_RS18440	COG3103	Sh3 type 3 domain protein
M2893_RS18445	COG2249	NAD(P)H dehydrogenase (quinone) activity
M2893_RS18450	COG3527	Alpha-acetolactate decarboxylase
M2893_RS18455	COG0028	Belongs to the TPP enzyme family
M2893_RS18460	COG0583	DNA-binding transcription factor activity
M2893_RS18465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M2893_RS18480	COG5337	Spore coat protein CotH
M2893_RS18490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M2893_RS18500	COG0405	Gamma-glutamyltransferase
M2893_RS18505	COG1522	sequence-specific DNA binding
M2893_RS18510	COG2059	Chromate
M2893_RS18515	COG2059	Chromate
M2893_RS18525	COG0655	NAD(P)H dehydrogenase (quinone) activity
M2893_RS18530	COG0583	DNA-binding transcription factor activity
M2893_RS18550	COG5444	nuclease activity
M2893_RS18565	COG3878	Protein conserved in bacteria
M2893_RS18570	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M2893_RS18575	COG4464	protein tyrosine phosphatase activity
M2893_RS18580	COG0489	protein tyrosine kinase activity
M2893_RS18585	COG3944	biosynthesis protein
M2893_RS18595	COG4715	Zinc finger, swim domain protein
M2893_RS18600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M2893_RS18605	COG0561	phosphatase activity
M2893_RS18610	COG1349	DNA-binding transcription factor activity
M2893_RS18615	COG0629	single-stranded DNA binding
M2893_RS18640	COG0457	Tetratricopeptide repeat
M2893_RS18645	COG4786	Flagellar basal body rod
M2893_RS18650	COG4786	Flagellar basal body rod
M2893_RS18655	COG1077	Cell shape determining protein MreB Mrl
M2893_RS18660	COG1609	Transcriptional regulator
M2893_RS18665	COG1846	Transcriptional regulator
M2893_RS18670	COG2814	Major facilitator Superfamily
M2893_RS18675	COG1953	Uracil, thiamine, allantoin
M2893_RS18680	COG0477	Major facilitator Superfamily
M2893_RS18685	COG1335	isochorismatase
M2893_RS18690	COG0004	ammonium transporteR
M2893_RS18695	COG0347	Belongs to the P(II) protein family
M2893_RS18700	COG0772	Belongs to the SEDS family
M2893_RS18705	COG0671	phosphoesterase, PA-phosphatase related
M2893_RS18715	COG0739	heme binding
M2893_RS18720	COG1247	-acetyltransferase
M2893_RS18735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M2893_RS18745	COG0726	polysaccharide deacetylase
M2893_RS18755	COG1959	2 iron, 2 sulfur cluster binding
M2893_RS18770	COG0831	urea catabolic process
M2893_RS18775	COG3237	CsbD-like
M2893_RS18780	COG1994	Peptidase M50
M2893_RS18785	COG0457	Tetratricopeptide repeat
M2893_RS18795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M2893_RS18805	COG2304	oxidoreductase activity
M2893_RS18810	COG2304	oxidoreductase activity
M2893_RS18815	COG2385	sporulation resulting in formation of a cellular spore
M2893_RS18820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M2893_RS18830	COG4836	Membrane
M2893_RS18900	COG0698	ribose 5-phosphate isomerase
M2893_RS18905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M2893_RS18915	COG0009	L-threonylcarbamoyladenylate synthase
M2893_RS18920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
M2893_RS18940	COG2890	protein-(glutamine-N5) methyltransferase activity
M2893_RS18945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
M2893_RS18950	COG0346	lactoylglutathione lyase activity
M2893_RS18955	COG0789	Transcriptional regulator
M2893_RS18960	COG0679	Auxin Efflux Carrier
M2893_RS18965	COG0281	malic enzyme
M2893_RS18980	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M2893_RS18990	COG1494	fructose-1,6-bisphosphatase
M2893_RS18995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M2893_RS19005	COG0191	fructose-bisphosphate aldolase activity
M2893_RS19010	COG2204	response regulator
M2893_RS19015	COG4821	SIS domain
M2893_RS19030	COG2181	nitrate reductase activity
M2893_RS19030	COG0247	lactate metabolic process
M2893_RS19035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M2893_RS19050	COG1132	(ABC) transporter
M2893_RS19055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M2893_RS19065	COG2181	nitrate reductase activity
M2893_RS19070	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
M2893_RS19075	COG1140	nitrate reductase beta subunit
M2893_RS19080	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
M2893_RS19085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M2893_RS19095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M2893_RS19100	COG2223	nitrite transmembrane transporter activity
M2893_RS19110	COG4506	Protein conserved in bacteria
M2893_RS19115	COG0457	Tetratricopeptide repeat
M2893_RS19155	COG0010	Belongs to the arginase family
M2893_RS19160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
M2893_RS19165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M2893_RS19180	COG1994	Peptidase M50
M2893_RS19185	COG1942	4-Oxalocrotonate Tautomerase
M2893_RS19190	COG1846	Transcriptional regulator
M2893_RS19195	COG0531	amino acid
M2893_RS19200	COG3465	dGTPase activity
M2893_RS19205	COG1078	dGTPase activity
M2893_RS19220	COG1695	Transcriptional regulator
M2893_RS19230	COG1131	(ABC) transporter
M2893_RS19235	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M2893_RS19265	COG0583	DNA-binding transcription factor activity
M2893_RS19270	COG2855	membrane
M2893_RS19275	COG0280	phosphate acetyltransferase
M2893_RS19285	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS19290	COG0436	Aminotransferase
M2893_RS19320	COG2814	Major facilitator Superfamily
M2893_RS19325	COG2814	Major facilitator Superfamily
M2893_RS19330	COG0833	amino acid
M2893_RS19335	COG4187	Peptidase family M20/M25/M40
M2893_RS19340	COG1012	belongs to the aldehyde dehydrogenase family
M2893_RS19345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M2893_RS19355	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
M2893_RS19360	COG1091	dTDP-4-dehydrorhamnose reductase activity
M2893_RS19365	COG1088	dTDP-glucose 4,6-dehydratase activity
M2893_RS19370	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M2893_RS19375	COG3980	spore coat polysaccharide biosynthesis protein
M2893_RS19380	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
M2893_RS19385	COG2089	acid synthase
M2893_RS19390	COG0456	acetyltransferase
M2893_RS19395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M2893_RS19400	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M2893_RS19405	COG0463	Glycosyl transferase, family 2
M2893_RS19415	COG2363	Small membrane protein
M2893_RS19420	COG2233	PERMEase
M2893_RS19435	COG1216	Glycosyl transferase, family 2
M2893_RS19450	COG1695	Transcriptional regulator
M2893_RS19455	COG0351	phosphomethylpyrimidine kinase
M2893_RS19465	COG1621	beta-fructofuranosidase activity
M2893_RS19470	COG1263	PTS System
M2893_RS19470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M2893_RS19475	COG3711	transcriptional antiterminator
M2893_RS19485	COG1404	Belongs to the peptidase S8 family
M2893_RS19490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M2893_RS19495	COG0778	Nitroreductase
M2893_RS19500	COG0772	Belongs to the SEDS family
M2893_RS19505	COG0454	-acetyltransferase
M2893_RS19525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M2893_RS19530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M2893_RS19535	COG2261	transglycosylase associated protein
M2893_RS19540	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M2893_RS19555	COG2246	polysaccharide biosynthetic process
M2893_RS19560	COG1309	transcriptional regulator
M2893_RS19580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M2893_RS19585	COG2837	iron assimilation
M2893_RS19605	COG0583	DNA-binding transcription factor activity
M2893_RS19615	COG1346	cytolysis
M2893_RS19620	COG4895	conserved protein (DUF2196)
M2893_RS19625	COG0789	Transcriptional regulator
M2893_RS19630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M2893_RS19635	COG0346	lactoylglutathione lyase activity
M2893_RS19640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M2893_RS19645	COG1404	Belongs to the peptidase S8 family
M2893_RS19650	COG1442	glycosyl transferase family 8
M2893_RS19655	COG1846	Transcriptional regulator
M2893_RS19660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M2893_RS19665	COG2357	RelA SpoT domain protein
M2893_RS19670	COG1575	Belongs to the MenA family. Type 1 subfamily
M2893_RS19685	COG1696	Membrane protein involved in D-alanine export
M2893_RS19695	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M2893_RS19700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M2893_RS19705	COG1486	melibiose metabolic process
M2893_RS19710	COG1447	Phosphotransferase system cellobiose-specific component IIA
M2893_RS19715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M2893_RS19720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M2893_RS19725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M2893_RS19725	COG3711	transcriptional antiterminator
M2893_RS19735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2893_RS19740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2893_RS19750	COG0640	Transcriptional regulator
M2893_RS19755	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M2893_RS19760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M2893_RS19765	COG1447	Phosphotransferase system cellobiose-specific component IIA
M2893_RS19770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M2893_RS19775	COG2723	6-phospho-beta-galactosidase activity
M2893_RS19780	COG1940	carbohydrate kinase activity
M2893_RS19785	COG1482	cell wall glycoprotein biosynthetic process
M2893_RS19795	COG0753	catalase activity
M2893_RS19800	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
M2893_RS19805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M2893_RS19810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M2893_RS19815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M2893_RS19820	COG4988	ABC transporter
M2893_RS19825	COG1294	oxidase, subunit
M2893_RS19830	COG1271	oxidase subunit
M2893_RS19835	COG3493	citrate carrier protein
M2893_RS19840	COG0726	polysaccharide deacetylase
M2893_RS19845	COG3842	ATPase activity
M2893_RS19850	COG2508	Transcriptional regulator
M2893_RS19855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M2893_RS19865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M2893_RS19880	COG4894	glucomannan catabolic process
M2893_RS19885	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M2893_RS19890	COG0500	methyltransferase
M2893_RS19895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M2893_RS19910	COG0693	protein deglycase activity
M2893_RS19910	COG0753	catalase activity
M2893_RS19915	COG2851	Citrate transporter
M2893_RS19920	COG2273	Hydrolase Family 16
M2893_RS19930	COG2270	Major facilitator Superfamily
M2893_RS19935	COG0513	Belongs to the DEAD box helicase family
M2893_RS19990	COG0697	spore germination
M2893_RS19995	COG0589	response to stress
M2893_RS20005	COG0494	nUDIX hydrolase
M2893_RS20010	COG3507	Belongs to the glycosyl hydrolase 43 family
M2893_RS20035	COG0010	Belongs to the arginase family
M2893_RS20040	COG0833	amino acid
M2893_RS20045	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
M2893_RS20050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M2893_RS20060	COG2390	Transcriptional regulator
M2893_RS20065	COG0561	phosphatase activity
M2893_RS20095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M2893_RS20100	COG5294	Protein conserved in bacteria
M2893_RS20105	COG0577	efflux transmembrane transporter activity
M2893_RS20110	COG1136	(ABC) transporter
M2893_RS20115	COG2205	protein histidine kinase activity
M2893_RS20120	COG0745	RESPONSE REGULATOR receiver
M2893_RS20135	COG1082	Xylose isomerase domain protein TIM barrel
M2893_RS20145	COG2814	Major facilitator Superfamily
M2893_RS20175	COG1349	DNA-binding transcription factor activity
M2893_RS20180	COG0667	Aldo Keto reductase
M2893_RS20185	COG2814	Major facilitator Superfamily
M2893_RS20200	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS20205	COG2197	response regulator
M2893_RS20210	COG4585	Histidine kinase
M2893_RS20215	COG3239	Fatty acid desaturase
M2893_RS20220	COG1309	transcriptional regulator
M2893_RS20225	COG1012	belongs to the aldehyde dehydrogenase family
M2893_RS20230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M2893_RS20240	COG0640	Transcriptional regulator
M2893_RS20245	COG2814	Major facilitator Superfamily
M2893_RS20250	COG1714	RDD family
M2893_RS20260	COG0450	alkyl hydroperoxide reductase
M2893_RS20265	COG3634	alkyl hydroperoxide reductase activity
M2893_RS20270	COG1113	amino acid transport
M2893_RS20280	COG2080	2 iron, 2 sulfur cluster binding
M2893_RS20295	COG2068	MobA-Related Protein
M2893_RS20300	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
M2893_RS20355	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
M2893_RS20360	COG0667	Aldo Keto reductase
M2893_RS20365	COG0456	acetyltransferase
M2893_RS20370	COG0457	Tetratricopeptide repeat
M2893_RS20375	COG0010	Belongs to the arginase family
M2893_RS20380	COG0833	amino acid
M2893_RS20385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M2893_RS20390	COG3829	transcription factor binding
M2893_RS20400	COG0488	(ABC) transporter
M2893_RS20415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M2893_RS20420	COG5002	protein histidine kinase activity
M2893_RS20430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M2893_RS20435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M2893_RS20440	COG4853	Protein conserved in bacteria
M2893_RS20445	COG4863	YycH protein
M2893_RS20450	COG5002	protein histidine kinase activity
M2893_RS20455	COG0745	RESPONSE REGULATOR receiver
M2893_RS20485	COG0346	lactoylglutathione lyase activity
M2893_RS20490	COG0305	Participates in initiation and elongation during chromosome replication
M2893_RS20505	COG3093	addiction module antidote protein HigA
M2893_RS20510	COG0297	glycogen (starch) synthase activity
M2893_RS20520	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
M2893_RS20525	COG0438	transferase activity, transferring glycosyl groups
M2893_RS20535	COG0515	serine threonine protein kinase
M2893_RS20545	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
M2893_RS20550	COG4241	membrane
M2893_RS20560	COG5577	PFAM Coat F domain
M2893_RS20565	COG1733	regulation of RNA biosynthetic process
M2893_RS20575	COG0697	spore germination
M2893_RS20580	COG1621	beta-fructofuranosidase activity
M2893_RS20585	COG1621	beta-fructofuranosidase activity
M2893_RS20590	COG1802	Transcriptional regulator
M2893_RS20595	COG2318	DinB family
M2893_RS20600	COG2211	Major facilitator Superfamily
M2893_RS20610	COG0778	Nitroreductase
M2893_RS20615	COG1846	Transcriptional regulator
M2893_RS20620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M2893_RS20625	COG1846	Transcriptional regulator
M2893_RS20640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M2893_RS20645	COG0583	DNA-binding transcription factor activity
M2893_RS20650	COG1028	Short-chain dehydrogenase reductase Sdr
M2893_RS20670	COG1404	Belongs to the peptidase S8 family
M2893_RS20675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M2893_RS20680	COG0697	spore germination
M2893_RS20690	COG1959	2 iron, 2 sulfur cluster binding
M2893_RS20695	COG1396	sequence-specific DNA binding
M2893_RS20705	COG1331	Highly conserved protein containing a thioredoxin domain
M2893_RS20710	COG1266	CAAX protease self-immunity
M2893_RS20715	COG2814	Major facilitator Superfamily
M2893_RS20715	COG0477	Major facilitator Superfamily
M2893_RS20720	COG0346	lactoylglutathione lyase activity
M2893_RS20725	COG1609	Transcriptional regulator
M2893_RS20730	COG0708	Exodeoxyribonuclease III
M2893_RS20735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M2893_RS20740	COG2169	Transcriptional regulator
M2893_RS20750	COG0629	single-stranded DNA binding
M2893_RS20760	COG0012	GTP binding
M2893_RS20765	COG0243	molybdopterin cofactor binding
M2893_RS20770	COG4481	Protein conserved in bacteria
M2893_RS20775	COG3949	Membrane
M2893_RS20790	COG1475	DNA binding
M2893_RS20795	COG1192	Involved in chromosome partitioning
M2893_RS20820	COG1847	R3H domain protein
M2893_RS20825	COG0706	membrane insertase activity