locus-tag	class	description
CF389_RS00020	COG3011	Protein conserved in bacteria
CF389_RS00030	COG2814	Major facilitator Superfamily
CF389_RS00035	COG5018	Exonuclease
CF389_RS00045	COG2205	protein histidine kinase activity
CF389_RS00050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CF389_RS00060	COG2267	carboxylic ester hydrolase activity
CF389_RS00065	COG1522	sequence-specific DNA binding
CF389_RS00070	COG0436	Aminotransferase
CF389_RS00075	COG1098	S1 RNA binding domain
CF389_RS00080	COG2155	Conserved Protein
CF389_RS00085	COG1979	alcohol dehydrogenase
CF389_RS00090	COG1979	alcohol dehydrogenase
CF389_RS00100	COG1335	isochorismatase
CF389_RS00130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CF389_RS00145	COG2738	Putative neutral zinc metallopeptidase
CF389_RS00150	COG1253	flavin adenine dinucleotide binding
CF389_RS00155	COG0366	Alpha amylase catalytic
CF389_RS00165	COG2070	2-Nitropropane dioxygenase
CF389_RS00180	COG0840	transmembrane signaling receptor activity
CF389_RS00185	COG0840	transmembrane signaling receptor activity
CF389_RS00190	COG0840	transmembrane signaling receptor activity
CF389_RS00195	COG0840	transmembrane signaling receptor activity
CF389_RS00200	COG0693	protein deglycase activity
CF389_RS00205	COG0673	inositol 2-dehydrogenase activity
CF389_RS00210	COG0628	permease
CF389_RS00235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF389_RS00235	COG1017	nitric oxide dioxygenase activity
CF389_RS00240	COG1705	Flagellar rod assembly protein muramidase FlgJ
CF389_RS00245	COG0569	domain protein
CF389_RS00255	COG1510	regulation of RNA biosynthetic process
CF389_RS00260	COG1012	belongs to the aldehyde dehydrogenase family
CF389_RS00265	COG1454	alcohol dehydrogenase
CF389_RS00275	COG2318	DinB family
CF389_RS00280	COG1585	Membrane protein implicated in regulation of membrane protease activity
CF389_RS00285	COG2268	Band 7 protein
CF389_RS00290	COG3859	Proton-coupled thiamine transporter YuaJ
CF389_RS00415	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CF389_RS00420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CF389_RS00425	COG1169	isochorismate synthase
CF389_RS00435	COG0596	Alpha beta hydrolase
CF389_RS00440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CF389_RS00450	COG4948	Mandelate Racemase Muconate Lactonizing
CF389_RS00465	COG1294	oxidase, subunit
CF389_RS00470	COG1271	oxidase subunit
CF389_RS00480	COG0288	reversible hydration of carbon dioxide
CF389_RS00505	COG0783	Belongs to the Dps family
CF389_RS00510	COG4824	toxin secretion phage lysis holin
CF389_RS00515	COG0494	nUDIX hydrolase
CF389_RS00520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CF389_RS00525	COG1116	anion transmembrane transporter activity
CF389_RS00530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CF389_RS00535	COG1506	peptidase
CF389_RS00555	COG0367	asparagine synthase
CF389_RS00560	COG1113	amino acid transport
CF389_RS00565	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CF389_RS00570	COG2267	carboxylic ester hydrolase activity
CF389_RS00580	COG0584	glycerophosphoryl diester phosphodiesterase
CF389_RS00590	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CF389_RS00595	COG1242	4 iron, 4 sulfur cluster binding
CF389_RS00605	COG1725	Transcriptional regulator
CF389_RS00610	COG1131	(ABC) transporter
CF389_RS00630	COG1136	(ABC) transporter
CF389_RS00635	COG0577	efflux transmembrane transporter activity
CF389_RS00640	COG0745	RESPONSE REGULATOR receiver
CF389_RS00645	COG2205	protein histidine kinase activity
CF389_RS00650	COG1136	(ABC) transporter
CF389_RS00655	COG0577	efflux transmembrane transporter activity
CF389_RS00660	COG5522	Integral membrane protein (intg_mem_TP0381)
CF389_RS00665	COG2814	Major facilitator Superfamily
CF389_RS00670	COG1366	Belongs to the anti-sigma-factor antagonist family
CF389_RS00670	COG2202	Pas domain
CF389_RS00685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF389_RS00695	COG1486	melibiose metabolic process
CF389_RS00700	COG0395	ABC-type sugar transport system, permease component
CF389_RS00705	COG1175	transmembrane transport
CF389_RS00710	COG1653	transport
CF389_RS00715	COG1609	Transcriptional regulator
CF389_RS00725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CF389_RS00730	COG2081	HI0933 family
CF389_RS00735	COG2244	polysaccharide biosynthetic process
CF389_RS00740	COG1187	pseudouridine synthase activity
CF389_RS00745	COG1349	DNA-binding transcription factor activity
CF389_RS00755	COG1131	(ABC) transporter
CF389_RS00760	COG4473	ABC transporter
CF389_RS00765	COG2252	PERMEase
CF389_RS00770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CF389_RS00775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CF389_RS00780	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CF389_RS00790	COG1597	lipid kinase activity
CF389_RS00795	COG0510	thiamine kinase activity
CF389_RS00810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CF389_RS00815	COG0281	malic enzyme
CF389_RS00820	COG5584	Small secreted protein
CF389_RS00825	COG1363	Peptidase, m42
CF389_RS00835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF389_RS00845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CF389_RS00850	COG1674	ftsk spoiiie
CF389_RS00860	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CF389_RS00865	COG4980	gas vesicle protein
CF389_RS00870	COG3118	belongs to the thioredoxin family
CF389_RS00875	COG1605	Chorismate mutase
CF389_RS00875	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CF389_RS00880	COG1609	Transcriptional regulator
CF389_RS00885	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CF389_RS00890	COG1360	Flagellar Motor Protein
CF389_RS00895	COG0123	including yeast histone deacetylase and acetoin utilization protein
CF389_RS00900	COG0517	IMP dehydrogenase activity
CF389_RS00905	COG0454	-acetyltransferase
CF389_RS00910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CF389_RS00935	COG1378	Sugar-specific transcriptional regulator TrmB
CF389_RS00940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CF389_RS00955	COG0693	protein deglycase activity
CF389_RS00965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF389_RS00965	COG1017	nitric oxide dioxygenase activity
CF389_RS00975	COG4282	regulation of fungal-type cell wall biogenesis
CF389_RS00980	COG1012	belongs to the aldehyde dehydrogenase family
CF389_RS01000	COG2199	diguanylate cyclase activity
CF389_RS01000	COG2203	Gaf domain
CF389_RS01005	COG1956	GAF domain-containing protein
CF389_RS01010	COG1309	transcriptional regulator
CF389_RS01015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CF389_RS01025	COG1114	Component of the transport system for branched-chain amino acids
CF389_RS01030	COG1104	cysteine desulfurase activity
CF389_RS01045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CF389_RS01050	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CF389_RS01055	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CF389_RS01060	COG0616	signal peptide processing
CF389_RS01065	COG1714	RDD family
CF389_RS01075	COG3874	Sporulation protein YtfJ
CF389_RS01080	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CF389_RS01085	COG0827	DNA restriction-modification system
CF389_RS01095	COG0521	Mo-molybdopterin cofactor biosynthetic process
CF389_RS01115	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS01125	COG4109	DRTGG domain
CF389_RS01135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CF389_RS01155	COG0587	DNA-directed DNA polymerase activity
CF389_RS01160	COG0281	malic enzyme
CF389_RS01180	COG0469	pyruvate kinase activity
CF389_RS01185	COG3030	protein affecting phage T7 exclusion by the F plasmid
CF389_RS01190	COG0628	permease
CF389_RS01215	COG0372	Belongs to the citrate synthase family
CF389_RS01220	COG0538	isocitrate dehydrogenase activity
CF389_RS01230	COG0745	RESPONSE REGULATOR receiver
CF389_RS01235	COG5002	protein histidine kinase activity
CF389_RS01240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CF389_RS01240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CF389_RS01245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CF389_RS01250	COG1971	Probably functions as a manganese efflux pump
CF389_RS01255	COG0237	dephospho-CoA kinase activity
CF389_RS01260	COG0656	L-ascorbic acid biosynthetic process
CF389_RS01265	COG2814	Major facilitator Superfamily
CF389_RS01270	COG1733	regulation of RNA biosynthetic process
CF389_RS01275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CF389_RS01290	COG3611	Membrane attachment protein
CF389_RS01295	COG1484	DNA-dependent DNA replication
CF389_RS01300	COG0398	Pfam SNARE associated Golgi protein
CF389_RS01315	COG1011	Hydrolase
CF389_RS01320	COG3275	phosphorelay sensor kinase activity
CF389_RS01325	COG3279	Response regulator of the LytR AlgR family
CF389_RS01330	COG1380	Effector of murein hydrolase LrgA
CF389_RS01335	COG1346	cytolysis
CF389_RS01340	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CF389_RS01350	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CF389_RS01355	COG3326	Membrane
CF389_RS01365	COG1363	Peptidase, m42
CF389_RS01370	COG3507	Belongs to the glycosyl hydrolase 43 family
CF389_RS01375	COG2160	L-arabinose isomerase activity
CF389_RS01380	COG1069	ribulokinase activity
CF389_RS01385	COG0235	Class ii aldolase
CF389_RS01390	COG0647	UMP catabolic process
CF389_RS01400	COG1653	transport
CF389_RS01405	COG1175	transmembrane transport
CF389_RS01410	COG0395	ABC-type sugar transport system, permease component
CF389_RS01415	COG3534	alpha-L-arabinofuranosidase
CF389_RS01420	COG1966	Carbon starvation protein
CF389_RS01425	COG0247	lactate metabolic process
CF389_RS01430	COG0277	FAD linked oxidase domain protein
CF389_RS01435	COG3835	regulator
CF389_RS01445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CF389_RS01450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CF389_RS01455	COG0072	phenylalanine-tRNA ligase activity
CF389_RS01455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CF389_RS01470	COG1286	toxin biosynthetic process
CF389_RS01475	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CF389_RS01475	COG1796	DNA polymerase
CF389_RS01485	COG3766	membrane
CF389_RS01495	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS01500	COG1309	transcriptional regulator
CF389_RS01505	COG1024	Enoyl-CoA hydratase
CF389_RS01510	COG2086	electron transfer activity
CF389_RS01515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CF389_RS01520	COG3534	alpha-L-arabinofuranosidase
CF389_RS01525	COG3118	belongs to the thioredoxin family
CF389_RS01540	COG0527	aspartate kinase activity
CF389_RS01545	COG1719	4-vinyl reductase, 4VR
CF389_RS01550	COG2009	succinate dehydrogenase
CF389_RS01555	COG1053	succinate dehydrogenase
CF389_RS01560	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CF389_RS01565	COG0824	Thioesterase
CF389_RS01570	COG2197	response regulator
CF389_RS01575	COG1846	Transcriptional regulator
CF389_RS01585	COG5401	PFAM Sporulation and spore germination
CF389_RS01595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CF389_RS01600	COG0622	Phosphoesterase
CF389_RS01625	COG0028	Belongs to the TPP enzyme family
CF389_RS01630	COG0440	acetolactate synthase activity
CF389_RS01645	COG0473	3-isopropylmalate dehydrogenase activity
CF389_RS01660	COG0457	Tetratricopeptide repeat
CF389_RS01660	COG1477	protein flavinylation
CF389_RS01675	COG0470	DNA polymerase III
CF389_RS01675	COG1067	ATP-dependent peptidase activity
CF389_RS01680	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CF389_RS01700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CF389_RS01710	COG1587	Uroporphyrinogen-III synthase
CF389_RS01715	COG0113	porphobilinogen synthase activity
CF389_RS01725	COG1388	LysM domain
CF389_RS01730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CF389_RS01740	COG0525	valine-tRNA ligase activity
CF389_RS01745	COG0285	dihydrofolate synthase activity
CF389_RS01750	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CF389_RS01770	COG1077	Cell shape determining protein MreB Mrl
CF389_RS01780	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CF389_RS01790	COG2894	cell division
CF389_RS01795	COG0739	heme binding
CF389_RS01800	COG1994	Peptidase M50
CF389_RS01810	COG2868	ribosomal protein
CF389_RS01815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CF389_RS01820	COG3290	protein histidine kinase activity
CF389_RS01835	COG0077	Prephenate dehydratase
CF389_RS01840	COG1827	regulation of RNA biosynthetic process
CF389_RS01845	COG1104	cysteine desulfurase activity
CF389_RS01850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CF389_RS01855	COG0157	Belongs to the NadC ModD family
CF389_RS01865	COG1388	LysM domain
CF389_RS01910	COG1862	Preprotein translocase
CF389_RS01920	COG2323	membrane
CF389_RS01925	COG2244	polysaccharide biosynthetic process
CF389_RS01935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CF389_RS01935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CF389_RS01940	COG0490	domain, Protein
CF389_RS01945	COG5416	Lipopolysaccharide assembly protein A domain
CF389_RS01950	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CF389_RS01950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CF389_RS01960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CF389_RS01970	COG4991	sh3 domain protein
CF389_RS01970	COG3103	Sh3 type 3 domain protein
CF389_RS01970	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF389_RS01995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CF389_RS02000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CF389_RS02005	COG1959	2 iron, 2 sulfur cluster binding
CF389_RS02010	COG1104	cysteine desulfurase activity
CF389_RS02020	COG0457	Tetratricopeptide repeat
CF389_RS02025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CF389_RS02030	COG3881	PFAM PRC-barrel domain
CF389_RS02045	COG0765	amino acid transport
CF389_RS02050	COG0765	amino acid transport
CF389_RS02055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF389_RS02060	COG1126	abc transporter atp-binding protein
CF389_RS02065	COG0628	permease
CF389_RS02075	COG4472	Bacterial protein of unknown function (DUF965)
CF389_RS02090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CF389_RS02095	COG4122	O-methyltransferase activity
CF389_RS02100	COG0826	peptidase U32
CF389_RS02105	COG0826	peptidase U32
CF389_RS02120	COG0768	penicillin binding
CF389_RS02145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CF389_RS02150	COG0626	cystathionine gamma-synthase activity
CF389_RS02160	COG2427	Protein of unknown function (DUF1641)
CF389_RS02165	COG3383	formate dehydrogenase (NAD+) activity
CF389_RS02170	COG5609	conserved protein (DUF2294)
CF389_RS02175	COG2116	formate transmembrane transporter activity
CF389_RS02190	COG2226	methyltransferase
CF389_RS02195	COG1309	transcriptional regulator
CF389_RS02200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CF389_RS02200	COG2124	cytochrome p450
CF389_RS02205	COG2814	Major facilitator Superfamily
CF389_RS02210	COG0583	DNA-binding transcription factor activity
CF389_RS02215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CF389_RS02225	COG3711	transcriptional antiterminator
CF389_RS02225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF389_RS02230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF389_RS02230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF389_RS02230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF389_RS02235	COG1482	cell wall glycoprotein biosynthetic process
CF389_RS02245	COG0561	phosphatase activity
CF389_RS02250	COG0561	phosphatase activity
CF389_RS02260	COG2318	DinB family
CF389_RS02265	COG0456	acetyltransferase
CF389_RS02270	COG2814	Major facilitator Superfamily
CF389_RS02280	COG0563	adenylate kinase activity
CF389_RS02290	COG3708	Transcriptional regulator
CF389_RS02290	COG2207	Transcriptional regulator
CF389_RS02305	COG4282	regulation of fungal-type cell wall biogenesis
CF389_RS02310	COG5444	nuclease activity
CF389_RS02345	COG0398	Pfam SNARE associated Golgi protein
CF389_RS02355	COG2755	lipolytic protein G-D-S-L family
CF389_RS02365	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CF389_RS02370	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CF389_RS02375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CF389_RS02380	COG1534	Rna-binding protein
CF389_RS02390	COG1713	HD superfamily hydrolase involved in NAD metabolism
CF389_RS02395	COG0799	negative regulation of ribosome biogenesis
CF389_RS02400	COG2226	methyltransferase
CF389_RS02405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CF389_RS02410	COG1555	photosystem II stabilization
CF389_RS02410	COG1596	polysaccharide export
CF389_RS02415	COG2131	deaminase
CF389_RS02420	COG0658	competence protein
CF389_RS02420	COG2333	competence protein COMEC
CF389_RS02430	COG1466	dna polymerase III delta subunit
CF389_RS02445	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF389_RS02460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CF389_RS02490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CF389_RS02495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CF389_RS02500	COG1283	sodium-dependent phosphate transmembrane transporter activity
CF389_RS02510	COG1610	YqeY-like protein
CF389_RS02515	COG1030	water channel activity
CF389_RS02520	COG4864	UPF0365 protein
CF389_RS02535	COG0561	phosphatase activity
CF389_RS02540	COG1702	phosphate starvation-inducible protein PhoH
CF389_RS02545	COG1480	7TM receptor with intracellular HD hydrolase
CF389_RS02555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CF389_RS02560	COG0295	cytidine deaminase activity
CF389_RS02565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CF389_RS02585	COG0751	glycine-tRNA ligase activity
CF389_RS02590	COG0517	IMP dehydrogenase activity
CF389_RS02605	COG0358	DNA primase activity
CF389_RS02610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CF389_RS02615	COG2010	Cytochrome c
CF389_RS02620	COG2384	SAM-dependent methyltransferase
CF389_RS02625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CF389_RS02640	COG0513	Belongs to the DEAD box helicase family
CF389_RS02655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CF389_RS02660	COG0735	belongs to the Fur family
CF389_RS02665	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CF389_RS02670	COG4709	membrane
CF389_RS02680	COG1388	LysM domain
CF389_RS02685	COG5521	maltodextrose utilization protein MalA
CF389_RS02690	COG2839	Protein conserved in bacteria
CF389_RS02695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CF389_RS02700	COG0477	Major facilitator Superfamily
CF389_RS02705	COG0768	penicillin binding
CF389_RS02710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CF389_RS02715	COG0573	inorganic phosphate transmembrane transporter activity
CF389_RS02720	COG0581	inorganic phosphate transmembrane transporter activity
CF389_RS02725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CF389_RS02730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CF389_RS02735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CF389_RS02750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CF389_RS02760	COG1757	Na H antiporter
CF389_RS02765	COG4483	Protein conserved in bacteria
CF389_RS02770	COG1940	carbohydrate kinase activity
CF389_RS02775	COG2866	Carboxypeptidase
CF389_RS02785	COG0011	TIGRFAM Protein of
CF389_RS02795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CF389_RS02805	COG1393	Belongs to the ArsC family
CF389_RS02815	COG1366	Belongs to the anti-sigma-factor antagonist family
CF389_RS02820	COG1253	flavin adenine dinucleotide binding
CF389_RS02825	COG0598	Magnesium transport protein CorA
CF389_RS02830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CF389_RS02835	COG1459	type II secretion system
CF389_RS02840	COG4537	Required for transformation and DNA binding
CF389_RS02845	COG4970	Tfp pilus assembly protein FimT
CF389_RS02855	COG4940	Competence protein ComGF
CF389_RS02880	COG0681	Belongs to the peptidase S26 family
CF389_RS02890	COG1396	sequence-specific DNA binding
CF389_RS02905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CF389_RS02925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF389_RS02940	COG1752	Esterase of the alpha-beta hydrolase superfamily
CF389_RS02950	COG3872	metal-dependent enzyme
CF389_RS02960	COG0006	proline dipeptidase activity
CF389_RS02975	COG3854	ATPases associated with a variety of cellular activities
CF389_RS03015	COG0511	ligase activity, forming carbon-carbon bonds
CF389_RS03020	COG0439	Biotin carboxylase
CF389_RS03025	COG1302	Protein conserved in bacteria
CF389_RS03040	COG1570	exodeoxyribonuclease VII activity
CF389_RS03050	COG0142	geranyltranstransferase activity
CF389_RS03060	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CF389_RS03070	COG0497	DNA recombination
CF389_RS03075	COG0750	zinc metalloprotease
CF389_RS03080	COG0745	RESPONSE REGULATOR receiver
CF389_RS03085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CF389_RS03100	COG1902	pentaerythritol trinitrate reductase activity
CF389_RS03120	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF389_RS03125	COG0584	glycerophosphoryl diester phosphodiesterase
CF389_RS03130	COG0183	Belongs to the thiolase family
CF389_RS03135	COG1250	3-hydroxyacyl-CoA dehydrogenase
CF389_RS03140	COG1960	acyl-CoA dehydrogenase activity
CF389_RS03145	COG0372	Belongs to the citrate synthase family
CF389_RS03150	COG2079	MmgE PrpD family protein
CF389_RS03155	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CF389_RS03165	COG3290	protein histidine kinase activity
CF389_RS03165	COG3829	transcription factor binding
CF389_RS03170	COG0280	phosphate acetyltransferase
CF389_RS03175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CF389_RS03180	COG3426	butyrate kinase activity
CF389_RS03185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF389_RS03190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CF389_RS03195	COG0022	dehydrogenase e1 component
CF389_RS03200	COG0508	dehydrogenase complex catalyzes the overall conversion of
CF389_RS03205	COG1597	lipid kinase activity
CF389_RS03215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF389_RS03220	COG0765	amino acid transport
CF389_RS03225	COG1126	abc transporter atp-binding protein
CF389_RS03230	COG4129	membrane
CF389_RS03235	COG1376	ErfK ybiS ycfS ynhG family protein
CF389_RS03240	COG0346	lactoylglutathione lyase activity
CF389_RS03245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CF389_RS03250	COG2195	Cleaves the N-terminal amino acid of tripeptides
CF389_RS03255	COG0706	membrane insertase activity
CF389_RS03270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CF389_RS03275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CF389_RS03290	COG0596	Alpha beta hydrolase
CF389_RS03315	COG0250	Participates in transcription elongation, termination and antitermination
CF389_RS03325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CF389_RS03325	COG2070	2-Nitropropane dioxygenase
CF389_RS03340	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS03350	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS03350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS03350	COG3321	synthase
CF389_RS03350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF389_RS03350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS03355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS03355	COG0300	oxidoreductase activity
CF389_RS03355	COG3321	synthase
CF389_RS03355	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS03355	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS03360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF389_RS03360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS03360	COG3321	synthase
CF389_RS03360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS03360	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS03365	COG0300	oxidoreductase activity
CF389_RS03365	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS03365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS03365	COG3321	synthase
CF389_RS03365	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS03370	COG3321	synthase
CF389_RS03370	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS03370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS03370	COG0300	oxidoreductase activity
CF389_RS03370	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS03375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF389_RS03375	COG3321	synthase
CF389_RS03375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS03375	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS03380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS03380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS03380	COG3321	synthase
CF389_RS03380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF389_RS03380	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS03385	COG2124	cytochrome p450
CF389_RS03390	COG3425	synthase
CF389_RS03395	COG1024	Enoyl-CoA hydratase
CF389_RS03400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CF389_RS03405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CF389_RS03410	COG0300	oxidoreductase activity
CF389_RS03415	COG3048	D-serine ammonia-lyase activity
CF389_RS03425	COG0346	lactoylglutathione lyase activity
CF389_RS03435	COG0628	permease
CF389_RS03450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CF389_RS03455	COG0456	acetyltransferase
CF389_RS03460	COG2329	Antibiotic biosynthesis monooxygenase
CF389_RS03465	COG0456	acetyltransferase
CF389_RS03465	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CF389_RS03470	COG4918	Iron-sulphur cluster biosynthesis
CF389_RS03480	COG1073	alpha beta
CF389_RS03490	COG0667	Aldo Keto reductase
CF389_RS03500	COG0494	nUDIX hydrolase
CF389_RS03505	COG1379	DNA repair
CF389_RS03510	COG1396	sequence-specific DNA binding
CF389_RS03515	COG0252	asparaginase activity
CF389_RS03520	COG1027	Aspartate ammonia-lyase
CF389_RS03525	COG1757	Na H antiporter
CF389_RS03530	COG0281	malic enzyme
CF389_RS03545	COG1300	Membrane
CF389_RS03550	COG0735	belongs to the Fur family
CF389_RS03560	COG4974	Belongs to the 'phage' integrase family
CF389_RS03565	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CF389_RS03570	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CF389_RS03575	COG1686	Belongs to the peptidase S11 family
CF389_RS03580	COG1366	Belongs to the anti-sigma-factor antagonist family
CF389_RS03590	COG1191	sigma factor activity
CF389_RS03610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CF389_RS03625	COG0697	spore germination
CF389_RS03630	COG0019	diaminopimelate decarboxylase activity
CF389_RS03635	COG4086	secreted protein
CF389_RS03640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CF389_RS03650	COG0681	Belongs to the peptidase S26 family
CF389_RS03660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CF389_RS03660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CF389_RS03665	COG0307	riboflavin synthase, alpha
CF389_RS03680	COG0456	acetyltransferase
CF389_RS03690	COG1547	Domain of unknown function (DUF309)
CF389_RS03715	COG1686	Belongs to the peptidase S11 family
CF389_RS03720	COG2715	membrane protein required for spore maturation
CF389_RS03725	COG0700	Nucleoside recognition
CF389_RS03730	COG1187	pseudouridine synthase activity
CF389_RS03735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF389_RS03740	COG1333	cytochrome c biogenesis protein
CF389_RS03745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CF389_RS03750	COG0745	RESPONSE REGULATOR receiver
CF389_RS03755	COG5002	protein histidine kinase activity
CF389_RS03760	COG1595	DNA-templated transcription, initiation
CF389_RS03770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CF389_RS03775	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CF389_RS03780	COG1141	Ferredoxin
CF389_RS03785	COG4955	Helix-turn-helix domain
CF389_RS03790	COG0514	ATP-dependent DNA helicase (RecQ)
CF389_RS03795	COG1266	CAAX protease self-immunity
CF389_RS03800	COG1388	LysM domain
CF389_RS03810	COG1408	metallophosphoesterase
CF389_RS03815	COG4862	establishment of competence for transformation
CF389_RS03820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CF389_RS03825	COG0492	ferredoxin-NADP+ reductase activity
CF389_RS03830	COG2339	peptidase activity
CF389_RS03835	COG3773	Cell wall hydrolase
CF389_RS03835	COG3409	Peptidoglycan-binding domain 1 protein
CF389_RS03840	COG2959	enzyme of heme biosynthesis
CF389_RS03845	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CF389_RS03860	COG0539	negative regulation of cytoplasmic translation
CF389_RS03900	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CF389_RS03905	COG0776	regulation of translation
CF389_RS03920	COG0142	geranyltranstransferase activity
CF389_RS03930	COG0142	geranyltranstransferase activity
CF389_RS03935	COG0105	UTP biosynthetic process
CF389_RS03940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CF389_RS03955	COG4401	Chorismate mutase type I
CF389_RS03960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CF389_RS03995	COG0287	Prephenate dehydrogenase
CF389_RS04005	COG0457	Tetratricopeptide repeat
CF389_RS04020	COG0723	plastoquinol--plastocyanin reductase activity
CF389_RS04025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CF389_RS04030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CF389_RS04030	COG2010	Cytochrome c
CF389_RS04035	COG4347	Protein of unknown function (DUF1405)
CF389_RS04045	COG2140	Oxalate decarboxylase
CF389_RS04050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CF389_RS04055	COG1694	Mazg nucleotide pyrophosphohydrolase
CF389_RS04070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CF389_RS04075	COG0438	transferase activity, transferring glycosyl groups
CF389_RS04105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CF389_RS04105	COG1199	ATP-dependent helicase activity
CF389_RS04115	COG5353	protein conserved in bacteria
CF389_RS04120	COG0436	Aminotransferase
CF389_RS04130	COG3935	DnaD domain protein
CF389_RS04135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CF389_RS04145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CF389_RS04145	COG4499	WXG100 protein secretion system (Wss), protein YukC
CF389_RS04185	COG0071	Belongs to the small heat shock protein (HSP20) family
CF389_RS04190	COG2190	(PTS) system
CF389_RS04195	COG1205	dead DEAH box helicase
CF389_RS04195	COG1111	helicase
CF389_RS04200	COG3359	exonuclease
CF389_RS04225	COG0116	Belongs to the methyltransferase superfamily
CF389_RS04245	COG1199	ATP-dependent helicase activity
CF389_RS04250	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CF389_RS04260	COG2233	PERMEase
CF389_RS04270	COG1335	isochorismatase
CF389_RS04295	COG3424	synthase
CF389_RS04300	COG1755	Isoprenylcysteine carboxyl methyltransferase
CF389_RS04310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CF389_RS04325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CF389_RS04335	COG0328	RNA-DNA hybrid ribonuclease activity
CF389_RS04340	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CF389_RS04345	COG0328	RNA-DNA hybrid ribonuclease activity
CF389_RS04365	COG1278	Cold shock
CF389_RS04370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CF389_RS04380	COG0386	Belongs to the glutathione peroxidase family
CF389_RS04385	COG1418	mRNA catabolic process
CF389_RS04390	COG1413	lyase activity
CF389_RS04405	COG2521	methyltransferase
CF389_RS04405	COG2136	Putative SAM-dependent methyltransferase
CF389_RS04420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CF389_RS04425	COG0204	Acyl-transferase
CF389_RS04430	COG1272	protein, Hemolysin III
CF389_RS04435	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CF389_RS04440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CF389_RS04450	COG1999	signal sequence binding
CF389_RS04455	COG2755	lipolytic protein G-D-S-L family
CF389_RS04460	COG4698	Protein conserved in bacteria
CF389_RS04465	COG1846	Transcriptional regulator
CF389_RS04480	COG1086	Polysaccharide biosynthesis protein
CF389_RS04490	COG4641	Protein conserved in bacteria
CF389_RS04505	COG0463	Glycosyl transferase, family 2
CF389_RS04510	COG0456	acetyltransferase
CF389_RS04520	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CF389_RS04525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CF389_RS04530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CF389_RS04535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CF389_RS04540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CF389_RS04545	COG0456	acetyltransferase
CF389_RS04550	COG1509	lysine 2,3-aminomutase activity
CF389_RS04585	COG0671	phosphoesterase, PA-phosphatase related
CF389_RS04605	COG1876	peptidase activity
CF389_RS04615	COG2226	methyltransferase
CF389_RS04620	COG0793	Belongs to the peptidase S41A family
CF389_RS04620	COG3409	Peptidoglycan-binding domain 1 protein
CF389_RS04625	COG2188	Transcriptional regulator
CF389_RS04630	COG2723	6-phospho-beta-galactosidase activity
CF389_RS04640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CF389_RS04650	COG0346	lactoylglutathione lyase activity
CF389_RS04655	COG0400	carboxylic ester hydrolase activity
CF389_RS04660	COG0778	Nitroreductase
CF389_RS04665	COG1733	regulation of RNA biosynthetic process
CF389_RS04675	COG1942	4-Oxalocrotonate Tautomerase
CF389_RS04690	COG2962	Rard protein
CF389_RS04700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CF389_RS04705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CF389_RS04710	COG1366	Belongs to the anti-sigma-factor antagonist family
CF389_RS04715	COG0534	Mate efflux family protein
CF389_RS04720	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CF389_RS04725	COG1819	glycosyl
CF389_RS04730	COG0791	NLP P60 protein
CF389_RS04730	COG1388	LysM domain
CF389_RS04735	COG2032	superoxide dismutase activity
CF389_RS04740	COG0714	Associated with various cellular activities
CF389_RS04745	COG4548	von Willebrand factor, type A
CF389_RS04755	COG0508	dehydrogenase complex catalyzes the overall conversion of
CF389_RS04760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CF389_RS04765	COG0385	Bile acid
CF389_RS04770	COG0733	neurotransmitter:sodium symporter activity
CF389_RS04775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CF389_RS04780	COG1657	PFAM Prenyltransferase squalene oxidase
CF389_RS04785	COG1012	belongs to the aldehyde dehydrogenase family
CF389_RS04815	COG0071	Belongs to the small heat shock protein (HSP20) family
CF389_RS04830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CF389_RS04835	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CF389_RS04845	COG0514	ATP-dependent DNA helicase (RecQ)
CF389_RS04850	COG3584	3D domain protein
CF389_RS04850	COG1388	LysM domain
CF389_RS04860	COG1619	proteins homologs of microcin C7 resistance protein MccF
CF389_RS04875	COG2322	membrane
CF389_RS04880	COG0741	lytic transglycosylase activity
CF389_RS04885	COG0640	Transcriptional regulator
CF389_RS04895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CF389_RS04900	COG1309	transcriptional regulator
CF389_RS04905	COG0662	Cupin 2, conserved barrel domain protein
CF389_RS04905	COG2207	Transcriptional regulator
CF389_RS04910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CF389_RS04915	COG1733	regulation of RNA biosynthetic process
CF389_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS04945	COG0243	molybdopterin cofactor binding
CF389_RS04950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CF389_RS04955	COG1070	Carbohydrate kinase
CF389_RS04960	COG2814	Major facilitator Superfamily
CF389_RS04970	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CF389_RS04975	COG0300	oxidoreductase activity
CF389_RS04990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CF389_RS04995	COG0583	DNA-binding transcription factor activity
CF389_RS05000	COG0067	glutamate synthase
CF389_RS05000	COG0070	glutamate synthase
CF389_RS05000	COG0069	glutamate synthase activity
CF389_RS05005	COG0493	'glutamate synthase
CF389_RS05030	COG0640	Transcriptional regulator
CF389_RS05035	COG2814	Major facilitator Superfamily
CF389_RS05040	COG0405	Gamma-glutamyltransferase
CF389_RS05045	COG0166	Belongs to the GPI family
CF389_RS05050	COG0582	viral genome integration into host DNA
CF389_RS05065	COG0534	Mate efflux family protein
CF389_RS05070	COG2017	converts alpha-aldose to the beta-anomer
CF389_RS05075	COG2027	D-alanyl-D-alanine carboxypeptidase
CF389_RS05085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS05090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS05095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS05100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS05105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS05105	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CF389_RS05115	COG1649	PFAM Uncharacterised BCR, COG1649
CF389_RS05120	COG1960	acyl-CoA dehydrogenase activity
CF389_RS05125	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS05130	COG0439	Biotin carboxylase
CF389_RS05135	COG0511	ligase activity, forming carbon-carbon bonds
CF389_RS05140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CF389_RS05145	COG1024	Enoyl-CoA hydratase
CF389_RS05150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CF389_RS05155	COG0586	Pfam SNARE associated Golgi protein
CF389_RS05160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CF389_RS05165	COG2246	polysaccharide biosynthetic process
CF389_RS05175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CF389_RS05195	COG2124	cytochrome p450
CF389_RS05200	COG2610	gluconate transmembrane transporter activity
CF389_RS05205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CF389_RS05210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CF389_RS05215	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS05245	COG3507	Belongs to the glycosyl hydrolase 43 family
CF389_RS05255	COG0745	RESPONSE REGULATOR receiver
CF389_RS05260	COG2205	protein histidine kinase activity
CF389_RS05295	COG2271	Major facilitator Superfamily
CF389_RS05300	COG1609	Transcriptional regulator
CF389_RS05305	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS05315	COG0800	Aldolase
CF389_RS05320	COG1063	alcohol dehydrogenase
CF389_RS05330	COG1115	amino acid carrier protein
CF389_RS05340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CF389_RS05345	COG0187	DNA topoisomerase II activity
CF389_RS05350	COG1832	CoA-binding protein
CF389_RS05360	COG4841	protein insertion into membrane
CF389_RS05370	COG0824	Thioesterase
CF389_RS05390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF389_RS05395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CF389_RS05410	COG0071	Belongs to the small heat shock protein (HSP20) family
CF389_RS05420	COG4846	Membrane protein involved in cytochrome C biogenesis
CF389_RS05425	COG2201	protein-glutamate methylesterase activity
CF389_RS05430	COG0785	Cytochrome C biogenesis protein
CF389_RS05450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CF389_RS05460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CF389_RS05490	COG4195	phage-related replication protein
CF389_RS05495	COG0756	dUTP diphosphatase activity
CF389_RS05505	COG5434	Belongs to the glycosyl hydrolase 28 family
CF389_RS05520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF389_RS05530	COG3397	chitin binding
CF389_RS05565	COG1064	alcohol dehydrogenase
CF389_RS05595	COG1070	Carbohydrate kinase
CF389_RS05610	COG3507	Belongs to the glycosyl hydrolase 43 family
CF389_RS05615	COG2211	Major facilitator Superfamily
CF389_RS05625	COG0174	glutamine synthetase
CF389_RS05630	COG0789	Transcriptional regulator
CF389_RS05635	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CF389_RS05640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CF389_RS05645	COG0464	growth
CF389_RS05655	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF389_RS05660	COG4112	unkown
CF389_RS05665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF389_RS05670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF389_RS05710	COG2076	Multidrug Resistance protein
CF389_RS05720	COG1764	response to oxidative stress
CF389_RS05725	COG4195	phage-related replication protein
CF389_RS05735	COG1404	Belongs to the peptidase S8 family
CF389_RS05745	COG3619	membrane
CF389_RS05750	COG3209	COG3209 Rhs family protein
CF389_RS05755	COG2124	cytochrome p450
CF389_RS05760	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CF389_RS05760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CF389_RS05760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS05760	COG3321	synthase
CF389_RS05765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS05765	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS05765	COG4221	oxidoreductase activity
CF389_RS05765	COG3321	synthase
CF389_RS05770	COG3321	synthase
CF389_RS05770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS05770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS05770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF389_RS05770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS05770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF389_RS05770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS05770	COG3321	synthase
CF389_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS05775	COG0300	oxidoreductase activity
CF389_RS05775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS05775	COG3321	synthase
CF389_RS05775	COG4221	oxidoreductase activity
CF389_RS05780	COG3321	synthase
CF389_RS05780	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS05780	COG0300	oxidoreductase activity
CF389_RS05780	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS05780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS05785	COG1024	Enoyl-CoA hydratase
CF389_RS05790	COG1024	Enoyl-CoA hydratase
CF389_RS05795	COG3425	synthase
CF389_RS05800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS05850	COG4550	Control of competence regulator ComK, YlbF/YmcA
CF389_RS05870	COG2359	stage V sporulation protein S
CF389_RS05875	COG1692	metallophosphoesterase
CF389_RS05885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF389_RS05900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CF389_RS05905	COG1426	Protein conserved in bacteria
CF389_RS05920	COG0300	oxidoreductase activity
CF389_RS05925	COG0612	Peptidase, M16
CF389_RS05930	COG0612	Peptidase, M16
CF389_RS05935	COG2409	Drug exporters of the RND superfamily
CF389_RS05935	COG1033	growth of symbiont in host cell
CF389_RS05940	COG1846	Transcriptional regulator
CF389_RS05945	COG2814	Major facilitator Superfamily
CF389_RS05950	COG2188	Transcriptional regulator
CF389_RS05955	COG4980	gas vesicle protein
CF389_RS05955	COG1674	ftsk spoiiie
CF389_RS05965	COG0740	serine-type endopeptidase activity
CF389_RS05970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CF389_RS05980	COG0527	aspartate kinase activity
CF389_RS05985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CF389_RS05990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CF389_RS05995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CF389_RS06000	COG1873	PFAM PRC-barrel domain
CF389_RS06005	COG0612	Peptidase, M16
CF389_RS06010	COG0726	polysaccharide deacetylase
CF389_RS06025	COG0196	riboflavin kinase activity
CF389_RS06040	COG1550	Protein conserved in bacteria
CF389_RS06050	COG1358	cellular component organization or biogenesis
CF389_RS06055	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CF389_RS06060	COG0195	Participates in both transcription termination and antitermination
CF389_RS06070	COG2176	DNA-directed DNA polymerase activity
CF389_RS06080	COG0750	zinc metalloprotease
CF389_RS06090	COG4589	Belongs to the CDS family
CF389_RS06095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CF389_RS06125	COG1191	sigma factor activity
CF389_RS06135	COG1776	CheC inhibitor of MCP methylation
CF389_RS06140	COG0835	chemotaxis
CF389_RS06145	COG2198	Histidine kinase
CF389_RS06145	COG0643	Histidine kinase
CF389_RS06150	COG2201	protein-glutamate methylesterase activity
CF389_RS06155	COG0455	bacterial-type flagellum organization
CF389_RS06160	COG1419	protein localization to endoplasmic reticulum
CF389_RS06165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CF389_RS06170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CF389_RS06175	COG1684	flagellar biosynthetic protein fliR
CF389_RS06180	COG1987	bacterial-type flagellum assembly
CF389_RS06185	COG1338	Plays a role in the flagellum-specific transport system
CF389_RS06190	COG3190	flagellar
CF389_RS06195	COG2201	protein-glutamate methylesterase activity
CF389_RS06200	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CF389_RS06200	COG1776	CheC inhibitor of MCP methylation
CF389_RS06205	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CF389_RS06210	COG1580	Controls the rotational direction of flagella during chemotaxis
CF389_RS06215	COG1582	Flagellar protein (FlbD)
CF389_RS06220	COG4786	Flagellar basal body rod
CF389_RS06225	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CF389_RS06230	COG3144	bacterial-type flagellum assembly
CF389_RS06235	COG3334	PFAM MgtE intracellular
CF389_RS06240	COG2882	bacterial-type flagellum organization
CF389_RS06245	COG1157	protein secretion by the type III secretion system
CF389_RS06250	COG1317	bacterial-type flagellum organization
CF389_RS06255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CF389_RS06260	COG1766	The M ring may be actively involved in energy transduction
CF389_RS06265	COG1677	Flagellar hook-basal body complex protein FliE
CF389_RS06270	COG1558	bacterial-type flagellum-dependent cell motility
CF389_RS06275	COG1815	bacterial-type flagellum-dependent cell motility
CF389_RS06295	COG4974	Belongs to the 'phage' integrase family
CF389_RS06305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CF389_RS06310	COG0758	DNA mediated transformation
CF389_RS06315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CF389_RS06325	COG2257	FlhB HrpN YscU SpaS Family
CF389_RS06340	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CF389_RS06365	COG1837	Belongs to the UPF0109 family
CF389_RS06375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CF389_RS06390	COG0552	protein localization to endoplasmic reticulum
CF389_RS06395	COG1196	nuclear chromosome segregation
CF389_RS06410	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS06415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CF389_RS06430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CF389_RS06435	COG1760	l-serine dehydratase
CF389_RS06440	COG1760	l-serine dehydratase
CF389_RS06445	COG1461	Dihydroxyacetone kinase
CF389_RS06450	COG1302	Protein conserved in bacteria
CF389_RS06465	COG1564	THIamine pyrophosphokinase
CF389_RS06470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CF389_RS06480	COG2815	serine threonine protein kinase
CF389_RS06480	COG0515	serine threonine protein kinase
CF389_RS06485	COG0631	protein serine/threonine phosphatase activity
CF389_RS06495	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CF389_RS06495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CF389_RS06505	COG0242	peptide deformylase activity
CF389_RS06510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CF389_RS06515	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CF389_RS06525	COG0194	GDP metabolic process
CF389_RS06535	COG1561	YicC-like family, N-terminal region
CF389_RS06540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CF389_RS06555	COG1648	precorrin-2 dehydrogenase activity
CF389_RS06560	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CF389_RS06565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CF389_RS06580	COG0306	phosphate transporter
CF389_RS06590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CF389_RS06595	COG0284	orotidine-5'-phosphate decarboxylase activity
CF389_RS06610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CF389_RS06615	COG0505	Belongs to the CarA family
CF389_RS06620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CF389_RS06630	COG2233	PERMEase
CF389_RS06640	COG0564	pseudouridine synthase activity
CF389_RS06650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CF389_RS06655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CF389_RS06665	COG3599	regulation of cell shape
CF389_RS06670	COG2302	S4 RNA-binding domain
CF389_RS06675	COG0762	integral membrane protein
CF389_RS06685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CF389_RS06690	COG1496	oxidoreductase activity
CF389_RS06695	COG1873	PFAM PRC-barrel domain
CF389_RS06700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CF389_RS06705	COG1119	ATPase activity
CF389_RS06710	COG1191	sigma factor activity
CF389_RS06715	COG1191	sigma factor activity
CF389_RS06725	COG1404	Belongs to the peptidase S8 family
CF389_RS06725	COG4412	M6 family metalloprotease domain protein
CF389_RS06730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CF389_RS06735	COG0849	cell division
CF389_RS06740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CF389_RS06755	COG0772	Belongs to the SEDS family
CF389_RS06775	COG0768	penicillin binding
CF389_RS06780	COG0768	penicillin binding
CF389_RS06785	COG4839	cell division protein FtsL
CF389_RS06805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CF389_RS06825	COG1399	metal-binding, possibly nucleic acid-binding protein
CF389_RS06835	COG3480	Lon protease (S16) C-terminal proteolytic domain
CF389_RS06840	COG1752	Esterase of the alpha-beta hydrolase superfamily
CF389_RS06845	COG3314	Sporulation integral membrane protein YlbJ
CF389_RS06855	COG0742	ribosomal rna small subunit methyltransferase
CF389_RS06870	COG3679	Belongs to the UPF0342 family
CF389_RS06885	COG2340	Cysteine-rich secretory protein family
CF389_RS06890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CF389_RS06900	COG3336	cytochrome c oxidase
CF389_RS06905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CF389_RS06910	COG1845	cytochrome c oxidase, subunit III
CF389_RS06915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CF389_RS06920	COG2010	Cytochrome c
CF389_RS06920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CF389_RS06935	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CF389_RS06940	COG0772	Belongs to the SEDS family
CF389_RS06950	COG2066	Belongs to the glutaminase family
CF389_RS06955	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CF389_RS06960	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CF389_RS06970	COG4896	Protein conserved in bacteria
CF389_RS06980	COG1217	gtp-binding protein TYPA
CF389_RS07000	COG1595	DNA-templated transcription, initiation
CF389_RS07005	COG3227	Zinc metalloprotease (Elastase)
CF389_RS07015	COG0483	inositol monophosphate 1-phosphatase activity
CF389_RS07045	COG1982	Orn Lys Arg decarboxylase major
CF389_RS07060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF389_RS07065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF389_RS07070	COG0508	dehydrogenase complex catalyzes the overall conversion of
CF389_RS07075	COG0022	dehydrogenase e1 component
CF389_RS07080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CF389_RS07085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF389_RS07090	COG3321	synthase
CF389_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS07090	COG4221	oxidoreductase activity
CF389_RS07090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS07095	COG3321	synthase
CF389_RS07095	COG0300	oxidoreductase activity
CF389_RS07095	COG4221	oxidoreductase activity
CF389_RS07095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS07100	COG0300	oxidoreductase activity
CF389_RS07100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS07100	COG4221	oxidoreductase activity
CF389_RS07100	COG3321	synthase
CF389_RS07105	COG4221	oxidoreductase activity
CF389_RS07105	COG3321	synthase
CF389_RS07105	COG0300	oxidoreductase activity
CF389_RS07105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS07110	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS07110	COG3321	synthase
CF389_RS07110	COG4221	oxidoreductase activity
CF389_RS07110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS07115	COG4221	oxidoreductase activity
CF389_RS07115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF389_RS07115	COG3321	synthase
CF389_RS07115	COG0300	oxidoreductase activity
CF389_RS07120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS07120	COG4221	oxidoreductase activity
CF389_RS07120	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS07120	COG3321	synthase
CF389_RS07135	COG0497	DNA recombination
CF389_RS07145	COG0242	peptide deformylase activity
CF389_RS07150	COG0561	phosphatase activity
CF389_RS07165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CF389_RS07175	COG0569	domain protein
CF389_RS07180	COG2105	PFAM AIG2 family protein
CF389_RS07180	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CF389_RS07185	COG3852	Histidine kinase
CF389_RS07190	COG2002	toxin-antitoxin pair type II binding
CF389_RS07200	COG1077	Cell shape determining protein MreB Mrl
CF389_RS07210	COG2309	aminopeptidase activity
CF389_RS07215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CF389_RS07220	COG0488	(ABC) transporter
CF389_RS07230	COG0681	Belongs to the peptidase S26 family
CF389_RS07235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF389_RS07235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF389_RS07235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF389_RS07240	COG1105	Belongs to the carbohydrate kinase PfkB family
CF389_RS07245	COG1349	DNA-binding transcription factor activity
CF389_RS07250	COG0577	efflux transmembrane transporter activity
CF389_RS07255	COG1136	(ABC) transporter
CF389_RS07260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF389_RS07270	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CF389_RS07275	COG0314	molybdopterin synthase activity
CF389_RS07280	COG1763	Mo-molybdopterin cofactor biosynthetic process
CF389_RS07285	COG0303	'Molybdopterin
CF389_RS07290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CF389_RS07310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF389_RS07315	COG0668	transmembrane transport
CF389_RS07335	COG0716	FMN binding
CF389_RS07345	COG0716	FMN binding
CF389_RS07350	COG0583	DNA-binding transcription factor activity
CF389_RS07355	COG0517	IMP dehydrogenase activity
CF389_RS07365	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CF389_RS07370	COG4703	Protein of unknown function (DUF1797)
CF389_RS07375	COG2200	EAL domain
CF389_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS07395	COG1408	metallophosphoesterase
CF389_RS07400	COG1376	ErfK ybiS ycfS ynhG family protein
CF389_RS07405	COG2814	Major facilitator Superfamily
CF389_RS07415	COG0835	chemotaxis
CF389_RS07415	COG0784	Response regulator, receiver
CF389_RS07430	COG0436	Aminotransferase
CF389_RS07435	COG4191	Histidine kinase
CF389_RS07440	COG0768	penicillin binding
CF389_RS07445	COG2340	Cysteine-rich secretory protein family
CF389_RS07450	COG0347	Belongs to the P(II) protein family
CF389_RS07460	COG2084	Dehydrogenase
CF389_RS07465	COG0840	transmembrane signaling receptor activity
CF389_RS07470	COG1533	DNA photolyase activity
CF389_RS07480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF389_RS07485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF389_RS07490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF389_RS07490	COG2190	(PTS) system
CF389_RS07490	COG1263	PTS System
CF389_RS07495	COG3711	transcriptional antiterminator
CF389_RS07500	COG1609	Transcriptional regulator
CF389_RS07505	COG0006	proline dipeptidase activity
CF389_RS07510	COG2217	Heavy metal translocating P-type atpase
CF389_RS07515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF389_RS07520	COG2244	polysaccharide biosynthetic process
CF389_RS07525	COG3773	Cell wall hydrolase
CF389_RS07535	COG4873	Protein conserved in bacteria
CF389_RS07550	COG0602	queuosine metabolic process
CF389_RS07555	COG0720	synthase
CF389_RS07570	COG3949	Membrane
CF389_RS07580	COG0542	response to heat
CF389_RS07585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CF389_RS07590	COG1360	Flagellar Motor Protein
CF389_RS07595	COG1846	Transcriptional regulator
CF389_RS07600	COG3852	Histidine kinase
CF389_RS07630	COG0436	Aminotransferase
CF389_RS07635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CF389_RS07655	COG5002	protein histidine kinase activity
CF389_RS07660	COG3594	Acyltransferase
CF389_RS07670	COG2323	membrane
CF389_RS07675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CF389_RS07700	COG1191	sigma factor activity
CF389_RS07705	COG0861	Integral membrane protein TerC family
CF389_RS07710	COG0586	Pfam SNARE associated Golgi protein
CF389_RS07720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CF389_RS07725	COG1793	dna ligase
CF389_RS07725	COG3285	dna ligase
CF389_RS07730	COG0726	polysaccharide deacetylase
CF389_RS07735	COG1846	Transcriptional regulator
CF389_RS07750	COG0789	Transcriptional regulator
CF389_RS07755	COG2239	Acts as a magnesium transporter
CF389_RS07775	COG3858	chitin binding
CF389_RS07775	COG1388	LysM domain
CF389_RS07780	COG4721	ABC-type cobalt transport system, permease component
CF389_RS07785	COG1122	ATPase activity
CF389_RS07790	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CF389_RS07795	COG1366	Belongs to the anti-sigma-factor antagonist family
CF389_RS07800	COG1404	Belongs to the peptidase S8 family
CF389_RS07810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF389_RS07815	COG2814	Major facilitator Superfamily
CF389_RS07825	COG0463	Glycosyl transferase, family 2
CF389_RS07825	COG0457	Tetratricopeptide repeat
CF389_RS07840	COG1764	response to oxidative stress
CF389_RS07845	COG1846	Transcriptional regulator
CF389_RS07850	COG1764	response to oxidative stress
CF389_RS07860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CF389_RS07865	COG0788	formyltetrahydrofolate deformylase activity
CF389_RS07870	COG2076	Multidrug Resistance protein
CF389_RS07875	COG2076	Multidrug Resistance protein
CF389_RS07880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF389_RS07885	COG1607	acyl-coa hydrolase
CF389_RS07890	COG1834	amidinotransferase
CF389_RS07895	COG2706	6-phosphogluconolactonase activity
CF389_RS07900	COG4608	Belongs to the ABC transporter superfamily
CF389_RS07905	COG0791	NLP P60 protein
CF389_RS07910	COG4948	Mandelate Racemase Muconate Lactonizing
CF389_RS07915	COG1619	proteins homologs of microcin C7 resistance protein MccF
CF389_RS07920	COG4166	transmembrane transport
CF389_RS07925	COG0444	Belongs to the ABC transporter superfamily
CF389_RS07930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF389_RS07935	COG0601	transmembrane transport
CF389_RS07940	COG2362	D-Aminopeptidase
CF389_RS07945	COG0477	Major facilitator Superfamily
CF389_RS07950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF389_RS07955	COG0463	Glycosyl transferase, family 2
CF389_RS07960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CF389_RS07965	COG0346	lactoylglutathione lyase activity
CF389_RS07970	COG0531	amino acid
CF389_RS07975	COG1392	Phosphate transport regulator
CF389_RS07980	COG0306	phosphate transporter
CF389_RS07995	COG5632	N-Acetylmuramoyl-L-alanine amidase
CF389_RS07995	COG3409	Peptidoglycan-binding domain 1 protein
CF389_RS08035	COG3778	Protein conserved in bacteria
CF389_RS08040	COG3299	homolog of phage Mu protein gp47
CF389_RS08045	COG3628	GPW Gp25 family protein
CF389_RS08055	COG4193	domain, Protein
CF389_RS08060	COG1652	LysM domain
CF389_RS08065	COG5412	phage tail tape measure protein
CF389_RS08065	COG3953	SLT domain
CF389_RS08065	COG3953	SLT domain
CF389_RS08065	COG5412	phage tail tape measure protein
CF389_RS08065	COG5412	phage tail tape measure protein
CF389_RS08065	COG3953	SLT domain
CF389_RS08115	COG4653	Phage capsid family
CF389_RS08120	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CF389_RS08125	COG5518	Phage portal protein
CF389_RS08130	COG1783	phage Terminase large subunit
CF389_RS08135	COG3728	DNA packaging
CF389_RS08135	COG5484	DNA packaging
CF389_RS08140	COG1595	DNA-templated transcription, initiation
CF389_RS08160	COG1484	DNA-dependent DNA replication
CF389_RS08165	COG1522	sequence-specific DNA binding
CF389_RS08175	COG1396	sequence-specific DNA binding
CF389_RS08180	COG2856	Zn peptidase
CF389_RS08185	COG4195	phage-related replication protein
CF389_RS08195	COG5632	N-Acetylmuramoyl-L-alanine amidase
CF389_RS08195	COG1388	LysM domain
CF389_RS08195	COG3409	Peptidoglycan-binding domain 1 protein
CF389_RS08205	COG0457	Tetratricopeptide repeat
CF389_RS08210	COG2318	DinB family
CF389_RS08215	COG0730	response to heat
CF389_RS08240	COG2197	response regulator
CF389_RS08245	COG4585	Histidine kinase
CF389_RS08265	COG2770	Histidine kinase
CF389_RS08265	COG2205	protein histidine kinase activity
CF389_RS08270	COG0745	RESPONSE REGULATOR receiver
CF389_RS08275	COG2721	sulfolactate sulfo-lyase activity
CF389_RS08280	COG0246	Mannitol dehydrogenase
CF389_RS08285	COG1609	Transcriptional regulator
CF389_RS08290	COG2211	Major facilitator Superfamily
CF389_RS08300	COG1252	NADH dehydrogenase
CF389_RS08310	COG4297	protein containing double-stranded beta helix domain
CF389_RS08315	COG0697	spore germination
CF389_RS08320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CF389_RS08325	COG0390	transport system, permease component
CF389_RS08330	COG1587	Uroporphyrinogen-III synthase
CF389_RS08340	COG1819	glycosyl
CF389_RS08345	COG2124	cytochrome p450
CF389_RS08350	COG2427	Protein of unknown function (DUF1641)
CF389_RS08355	COG3383	formate dehydrogenase (NAD+) activity
CF389_RS08365	COG2205	protein histidine kinase activity
CF389_RS08380	COG1285	pathogenesis
CF389_RS08395	COG1349	DNA-binding transcription factor activity
CF389_RS08405	COG1447	Phosphotransferase system cellobiose-specific component IIA
CF389_RS08410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF389_RS08410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF389_RS08415	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CF389_RS08420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CF389_RS08425	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CF389_RS08435	COG1846	Transcriptional regulator
CF389_RS08445	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CF389_RS08450	COG2367	Beta-lactamase
CF389_RS08455	COG0346	lactoylglutathione lyase activity
CF389_RS08465	COG5444	nuclease activity
CF389_RS08480	COG0626	cystathionine gamma-synthase activity
CF389_RS08485	COG0626	cystathionine gamma-synthase activity
CF389_RS08490	COG2382	esterase
CF389_RS08500	COG2153	protein acetylation
CF389_RS08510	COG1131	(ABC) transporter
CF389_RS08530	COG0210	DNA helicase
CF389_RS08585	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CF389_RS08590	COG0351	phosphomethylpyrimidine kinase
CF389_RS08595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CF389_RS08605	COG2104	thiamine diphosphate biosynthetic process
CF389_RS08610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CF389_RS08615	COG0352	thiamine-phosphate diphosphorylase activity
CF389_RS08620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CF389_RS08625	COG0475	glutathione-regulated potassium exporter activity
CF389_RS08625	COG0569	domain protein
CF389_RS08640	COG0564	pseudouridine synthase activity
CF389_RS08645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CF389_RS08650	COG2357	RelA SpoT domain protein
CF389_RS08660	COG4116	CYTH
CF389_RS08665	COG0741	lytic transglycosylase activity
CF389_RS08670	COG2346	COG2346, Truncated hemoglobins
CF389_RS08675	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CF389_RS08685	COG1164	Oligoendopeptidase f
CF389_RS08690	COG4469	Competence protein
CF389_RS08695	COG4862	establishment of competence for transformation
CF389_RS08700	COG0861	Integral membrane protein TerC family
CF389_RS08705	COG1393	Belongs to the ArsC family
CF389_RS08710	COG0456	acetyltransferase
CF389_RS08720	COG4608	Belongs to the ABC transporter superfamily
CF389_RS08725	COG0444	Belongs to the ABC transporter superfamily
CF389_RS08730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF389_RS08735	COG0601	transmembrane transport
CF389_RS08740	COG4166	transmembrane transport
CF389_RS08745	COG0180	Tryptophanyl-tRNA synthetase
CF389_RS08755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF389_RS08760	COG0601	transmembrane transport
CF389_RS08770	COG4608	Belongs to the ABC transporter superfamily
CF389_RS08775	COG0444	Belongs to the ABC transporter superfamily
CF389_RS08780	COG5504	Zn-dependent protease
CF389_RS08785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CF389_RS08790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CF389_RS08805	COG1744	ABC transporter substrate-binding protein PnrA-like
CF389_RS08815	COG2267	carboxylic ester hydrolase activity
CF389_RS08835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CF389_RS08840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CF389_RS08845	COG0505	Belongs to the CarA family
CF389_RS08850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CF389_RS08860	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CF389_RS08870	COG2271	Major facilitator Superfamily
CF389_RS08875	COG0277	FAD linked oxidase domain protein
CF389_RS08885	COG2151	metal-sulfur cluster biosynthetic enzyme
CF389_RS08890	COG1073	alpha beta
CF389_RS08895	COG0561	phosphatase activity
CF389_RS08910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CF389_RS08915	COG1307	EDD domain protein, DegV family
CF389_RS08925	COG0840	transmembrane signaling receptor activity
CF389_RS08930	COG1744	ABC transporter substrate-binding protein PnrA-like
CF389_RS08935	COG2996	Protein conserved in bacteria
CF389_RS08945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CF389_RS08945	COG0646	methionine synthase
CF389_RS08950	COG2153	protein acetylation
CF389_RS08955	COG1357	PFAM Pentapeptide repeats (8 copies)
CF389_RS08960	COG1279	arginine transmembrane transporter activity
CF389_RS08965	COG2318	DinB family
CF389_RS08970	COG0673	inositol 2-dehydrogenase activity
CF389_RS08975	COG1609	Transcriptional regulator
CF389_RS08980	COG1917	Cupin 2, conserved barrel domain protein
CF389_RS08980	COG2207	Transcriptional regulator
CF389_RS08985	COG0534	Mate efflux family protein
CF389_RS08990	COG1562	ergosterol biosynthetic process
CF389_RS08995	COG0367	asparagine synthase
CF389_RS09015	COG0179	Fumarylacetoacetate (FAA) hydrolase
CF389_RS09055	COG1403	HNH endonuclease
CF389_RS09060	COG0419	ATPase involved in DNA repair
CF389_RS09065	COG0420	3'-5' exonuclease activity
CF389_RS09080	COG2323	membrane
CF389_RS09085	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CF389_RS09095	COG2814	Major facilitator Superfamily
CF389_RS09100	COG3180	Ammonia monooxygenase
CF389_RS09105	COG1846	Transcriptional regulator
CF389_RS09110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CF389_RS09115	COG0681	Belongs to the peptidase S26 family
CF389_RS09120	COG0398	Pfam SNARE associated Golgi protein
CF389_RS09135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CF389_RS09155	COG5646	InterPro IPR014922
CF389_RS09165	COG4903	ComK protein
CF389_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS09180	COG0723	plastoquinol--plastocyanin reductase activity
CF389_RS09180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CF389_RS09185	COG0840	transmembrane signaling receptor activity
CF389_RS09190	COG1268	BioY protein
CF389_RS09195	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS09200	COG0183	Belongs to the thiolase family
CF389_RS09205	COG0406	alpha-ribazole phosphatase activity
CF389_RS09210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CF389_RS09220	COG1404	Belongs to the peptidase S8 family
CF389_RS09225	COG0501	Belongs to the peptidase M48B family
CF389_RS09235	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS09240	COG0702	epimerase
CF389_RS09245	COG0095	Lipoate-protein ligase
CF389_RS09250	COG1234	tRNA 3'-trailer cleavage
CF389_RS09260	COG1301	dicarboxylic acid transport
CF389_RS09265	COG1363	Peptidase, m42
CF389_RS09275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CF389_RS09280	COG1511	domain protein
CF389_RS09285	COG1309	transcriptional regulator
CF389_RS09290	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CF389_RS09295	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CF389_RS09305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CF389_RS09310	COG2329	Antibiotic biosynthesis monooxygenase
CF389_RS09315	COG3069	C4-dicarboxylate transmembrane transporter activity
CF389_RS09320	COG1473	amidohydrolase
CF389_RS09330	COG4473	ABC transporter
CF389_RS09335	COG1131	(ABC) transporter
CF389_RS09340	COG0537	adenosine 5'-monophosphoramidase activity
CF389_RS09345	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CF389_RS09360	COG4980	gas vesicle protein
CF389_RS09400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CF389_RS09415	COG4717	serine-type aminopeptidase activity
CF389_RS09420	COG0420	3'-5' exonuclease activity
CF389_RS09425	COG1668	transmembrane transport
CF389_RS09430	COG4152	abc transporter atp-binding protein
CF389_RS09440	COG1024	Enoyl-CoA hydratase
CF389_RS09450	COG0490	domain, Protein
CF389_RS09455	COG0475	glutathione-regulated potassium exporter activity
CF389_RS09465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CF389_RS09470	COG0561	phosphatase activity
CF389_RS09475	COG4335	DNA alkylation repair
CF389_RS09490	COG0189	ligase activity
CF389_RS09495	COG0189	ligase activity
CF389_RS09520	COG0702	epimerase
CF389_RS09525	COG1132	(ABC) transporter
CF389_RS09530	COG1132	(ABC) transporter
CF389_RS09535	COG0589	response to stress
CF389_RS09545	COG3226	Transcriptional regulator
CF389_RS09550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CF389_RS09555	COG0726	polysaccharide deacetylase
CF389_RS09560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CF389_RS09565	COG0668	transmembrane transport
CF389_RS09575	COG0584	glycerophosphoryl diester phosphodiesterase
CF389_RS09580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CF389_RS09585	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CF389_RS09590	COG1253	flavin adenine dinucleotide binding
CF389_RS09595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CF389_RS09600	COG0436	Aminotransferase
CF389_RS09605	COG0789	Transcriptional regulator
CF389_RS09610	COG1253	flavin adenine dinucleotide binding
CF389_RS09615	COG0204	Acyl-transferase
CF389_RS09620	COG1595	DNA-templated transcription, initiation
CF389_RS09635	COG0733	neurotransmitter:sodium symporter activity
CF389_RS09640	COG0531	amino acid
CF389_RS09645	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS09650	COG0372	Belongs to the citrate synthase family
CF389_RS09655	COG0583	DNA-binding transcription factor activity
CF389_RS09660	COG1388	LysM domain
CF389_RS09660	COG0791	NLP P60 protein
CF389_RS09665	COG1785	Belongs to the alkaline phosphatase family
CF389_RS09670	COG2719	SpoVR family
CF389_RS09675	COG0668	transmembrane transport
CF389_RS09680	COG1959	2 iron, 2 sulfur cluster binding
CF389_RS09685	COG0791	NLP P60 protein
CF389_RS09685	COG1388	LysM domain
CF389_RS09700	COG0431	NADPH-dependent FMN reductase
CF389_RS09705	COG2197	response regulator
CF389_RS09710	COG4585	Histidine kinase
CF389_RS09710	COG2203	Gaf domain
CF389_RS09715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CF389_RS09720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CF389_RS09730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CF389_RS09735	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CF389_RS09740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CF389_RS09745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CF389_RS09745	COG3153	acetyltransferase
CF389_RS09750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF389_RS09755	COG0517	IMP dehydrogenase activity
CF389_RS09765	COG0564	pseudouridine synthase activity
CF389_RS09770	COG3764	Sortase (surface protein transpeptidase)
CF389_RS09775	COG4085	toxin activity
CF389_RS09775	COG1525	nuclease
CF389_RS09775	COG0737	Belongs to the 5'-nucleotidase family
CF389_RS09780	COG5577	PFAM Coat F domain
CF389_RS09800	COG1823	symporter activity
CF389_RS09805	COG3706	GGDEF domain
CF389_RS09810	COG1464	Belongs to the NlpA lipoprotein family
CF389_RS09820	COG1278	Cold shock
CF389_RS09825	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CF389_RS09830	COG1131	(ABC) transporter
CF389_RS09835	COG1131	(ABC) transporter
CF389_RS09840	COG1725	Transcriptional regulator
CF389_RS09855	COG0655	NAD(P)H dehydrogenase (quinone) activity
CF389_RS09860	COG2814	Major facilitator Superfamily
CF389_RS09865	COG1566	PFAM secretion protein HlyD family protein
CF389_RS09870	COG1846	Transcriptional regulator
CF389_RS09885	COG2766	serine protein kinase
CF389_RS09890	COG1664	Polymer-forming cytoskeletal
CF389_RS09895	COG1664	Polymer-forming cytoskeletal
CF389_RS09900	COG0789	Transcriptional regulator
CF389_RS09905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CF389_RS09915	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CF389_RS09920	COG3382	B3 4 domain protein
CF389_RS09930	COG1476	TRANSCRIPTIONal
CF389_RS09950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CF389_RS09955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CF389_RS09960	COG1116	anion transmembrane transporter activity
CF389_RS09975	COG0753	catalase activity
CF389_RS09980	COG4608	Belongs to the ABC transporter superfamily
CF389_RS09985	COG0444	Belongs to the ABC transporter superfamily
CF389_RS09990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF389_RS09995	COG0601	transmembrane transport
CF389_RS10000	COG0747	negative chemotaxis
CF389_RS10010	COG0277	FAD linked oxidase domain protein
CF389_RS10020	COG3340	Belongs to the peptidase S51 family
CF389_RS10135	COG0735	belongs to the Fur family
CF389_RS10140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CF389_RS10150	COG4129	membrane
CF389_RS10155	COG1132	(ABC) transporter
CF389_RS10175	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS10185	COG1194	a g-specific adenine glycosylase
CF389_RS10190	COG1988	membrane-bound metal-dependent
CF389_RS10195	COG4485	Bacterial membrane protein, YfhO
CF389_RS10200	COG0463	Glycosyl transferase, family 2
CF389_RS10205	COG0596	Alpha beta hydrolase
CF389_RS10210	COG5658	integral membrane protein
CF389_RS10215	COG3103	Sh3 type 3 domain protein
CF389_RS10230	COG3591	Belongs to the peptidase S1B family
CF389_RS10240	COG2814	Major facilitator Superfamily
CF389_RS10255	COG1090	epimerase
CF389_RS10270	COG0778	Nitroreductase
CF389_RS10275	COG0384	phenazine biosynthesis protein PhzF
CF389_RS10280	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CF389_RS10280	COG0392	lysyltransferase activity
CF389_RS10285	COG1846	Transcriptional regulator
CF389_RS10290	COG2814	Major facilitator Superfamily
CF389_RS10295	COG2318	DinB family
CF389_RS10300	COG2732	(Barnase) inhibitor
CF389_RS10305	COG0574	Belongs to the PEP-utilizing enzyme family
CF389_RS10305	COG3848	Pyruvate phosphate dikinase
CF389_RS10310	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CF389_RS10315	COG2249	NAD(P)H dehydrogenase (quinone) activity
CF389_RS10320	COG1695	Transcriptional regulator
CF389_RS10335	COG2514	catechol 2,3-dioxygenase activity
CF389_RS10340	COG2259	Doxx family
CF389_RS10345	COG1132	(ABC) transporter
CF389_RS10350	COG1132	(ABC) transporter
CF389_RS10355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF389_RS10355	COG1263	PTS System
CF389_RS10360	COG1737	Transcriptional regulator
CF389_RS10365	COG1486	melibiose metabolic process
CF389_RS10375	COG3284	Transcriptional regulator
CF389_RS10380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF389_RS10385	COG0508	dehydrogenase complex catalyzes the overall conversion of
CF389_RS10390	COG0022	dehydrogenase e1 component
CF389_RS10395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CF389_RS10400	COG4637	Psort location Cytoplasmic, score
CF389_RS10405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CF389_RS10415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CF389_RS10420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CF389_RS10425	COG0598	Magnesium transport protein CorA
CF389_RS10435	COG2084	Dehydrogenase
CF389_RS10440	COG0726	polysaccharide deacetylase
CF389_RS10450	COG0535	radical SAM domain protein
CF389_RS10455	COG0668	transmembrane transport
CF389_RS10465	COG0387	Pfam Sodium calcium exchanger
CF389_RS10470	COG0477	Major facilitator Superfamily
CF389_RS10475	COG1295	ribonuclease BN
CF389_RS10480	COG4980	gas vesicle protein
CF389_RS10485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CF389_RS10495	COG2814	Major facilitator Superfamily
CF389_RS10510	COG1609	Transcriptional regulator
CF389_RS10515	COG0693	protein deglycase activity
CF389_RS10520	COG0737	Belongs to the 5'-nucleotidase family
CF389_RS10535	COG0778	Nitroreductase
CF389_RS10540	COG2188	Transcriptional regulator
CF389_RS10545	COG0366	Alpha amylase catalytic
CF389_RS10550	COG1263	PTS System
CF389_RS10550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF389_RS10565	COG0071	Belongs to the small heat shock protein (HSP20) family
CF389_RS10575	COG1368	sulfuric ester hydrolase activity
CF389_RS10585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF389_RS10585	COG1263	PTS System
CF389_RS10590	COG0024	Methionine aminopeptidase
CF389_RS10610	COG2258	MOSC domain
CF389_RS10620	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CF389_RS10625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CF389_RS10630	COG2851	Citrate transporter
CF389_RS10635	COG3181	Tripartite tricarboxylate transporter family receptor
CF389_RS10640	COG4565	transcriptional regulatory protein
CF389_RS10645	COG3290	protein histidine kinase activity
CF389_RS10650	COG3764	Sortase (surface protein transpeptidase)
CF389_RS10660	COG3279	Response regulator of the LytR AlgR family
CF389_RS10665	COG2972	Histidine kinase
CF389_RS10665	COG0745	RESPONSE REGULATOR receiver
CF389_RS10685	COG0471	metal ion transport
CF389_RS10690	COG3866	Pectate lyase
CF389_RS10705	COG2130	NADP-dependent
CF389_RS10710	COG0456	acetyltransferase
CF389_RS10715	COG0513	Belongs to the DEAD box helicase family
CF389_RS10720	COG0488	(ABC) transporter
CF389_RS10725	COG2814	Major facilitator Superfamily
CF389_RS10730	COG0789	Transcriptional regulator
CF389_RS10735	COG0488	(ABC) transporter
CF389_RS10740	COG0457	Tetratricopeptide repeat
CF389_RS10740	COG0463	Glycosyl transferase, family 2
CF389_RS10745	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS10750	COG0840	transmembrane signaling receptor activity
CF389_RS10755	COG1012	belongs to the aldehyde dehydrogenase family
CF389_RS10760	COG0531	amino acid
CF389_RS10765	COG2223	nitrite transmembrane transporter activity
CF389_RS10770	COG1442	glycosyl transferase family 8
CF389_RS10775	COG1216	Glycosyl transferase, family 2
CF389_RS10780	COG1442	glycosyl transferase family 8
CF389_RS10785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF389_RS10790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CF389_RS10795	COG1368	sulfuric ester hydrolase activity
CF389_RS10800	COG2124	cytochrome p450
CF389_RS10800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CF389_RS10810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CF389_RS10815	COG1846	Transcriptional regulator
CF389_RS10820	COG0670	Belongs to the BI1 family
CF389_RS10825	COG0196	riboflavin kinase activity
CF389_RS10830	COG5583	Uncharacterized small protein (DUF2292)
CF389_RS10835	COG1366	Belongs to the anti-sigma-factor antagonist family
CF389_RS10845	COG0346	lactoylglutathione lyase activity
CF389_RS10850	COG2329	Antibiotic biosynthesis monooxygenase
CF389_RS10855	COG2323	membrane
CF389_RS10865	COG0454	-acetyltransferase
CF389_RS10870	COG3546	catalase activity
CF389_RS10905	COG5444	nuclease activity
CF389_RS10930	COG1131	(ABC) transporter
CF389_RS10940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CF389_RS10945	COG1597	lipid kinase activity
CF389_RS10950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF389_RS10955	COG1309	transcriptional regulator
CF389_RS10975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CF389_RS10980	COG1285	pathogenesis
CF389_RS10985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CF389_RS10990	COG4851	CamS sex pheromone cAM373 precursor
CF389_RS11000	COG0210	DNA helicase
CF389_RS11015	COG0069	glutamate synthase activity
CF389_RS11020	COG4496	protein, YerC YecD
CF389_RS11025	COG1470	cell adhesion involved in biofilm formation
CF389_RS11030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CF389_RS11040	COG0151	Belongs to the GarS family
CF389_RS11045	COG0138	bifunctional purine biosynthesis protein purh
CF389_RS11050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CF389_RS11060	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CF389_RS11075	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CF389_RS11080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CF389_RS11085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CF389_RS11090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CF389_RS11095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CF389_RS11115	COG3064	Membrane
CF389_RS11120	COG2252	PERMEase
CF389_RS11140	COG1305	Transglutaminase-like
CF389_RS11145	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CF389_RS11150	COG0714	Associated with various cellular activities
CF389_RS11155	COG1113	amino acid transport
CF389_RS11160	COG2132	Multicopper oxidase
CF389_RS11170	COG0823	Involved in the tonB-independent uptake of proteins
CF389_RS11175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CF389_RS11180	COG1063	alcohol dehydrogenase
CF389_RS11185	COG1595	DNA-templated transcription, initiation
CF389_RS11195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CF389_RS11195	COG2755	lipolytic protein G-D-S-L family
CF389_RS11200	COG4260	virion core protein, lumpy skin disease virus
CF389_RS11205	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CF389_RS11210	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CF389_RS11215	COG1842	Phage shock protein A
CF389_RS11225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF389_RS11230	COG2211	Major facilitator Superfamily
CF389_RS11235	COG1063	alcohol dehydrogenase
CF389_RS11240	COG0457	Tetratricopeptide repeat
CF389_RS11255	COG3409	Peptidoglycan-binding domain 1 protein
CF389_RS11270	COG1266	CAAX protease self-immunity
CF389_RS11280	COG0805	protein transport
CF389_RS11285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CF389_RS11300	COG0488	(ABC) transporter
CF389_RS11305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CF389_RS11310	COG0456	acetyltransferase
CF389_RS11315	COG1214	PFAM Peptidase M22, glycoprotease
CF389_RS11320	COG0802	atpase or kinase
CF389_RS11325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CF389_RS11365	COG2814	Major facilitator Superfamily
CF389_RS11370	COG0604	alcohol dehydrogenase
CF389_RS11375	COG3832	glyoxalase III activity
CF389_RS11385	COG0531	amino acid
CF389_RS11390	COG1309	transcriptional regulator
CF389_RS11395	COG2076	Multidrug Resistance protein
CF389_RS11400	COG2076	Multidrug Resistance protein
CF389_RS11405	COG2807	transmembrane transport
CF389_RS11410	COG2186	Transcriptional regulator
CF389_RS11415	COG2188	Transcriptional regulator
CF389_RS11420	COG2814	Major facilitator Superfamily
CF389_RS11425	COG1388	LysM domain
CF389_RS11430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF389_RS11445	COG1819	glycosyl
CF389_RS11450	COG1802	Transcriptional regulator
CF389_RS11460	COG2226	methyltransferase
CF389_RS11465	COG1051	belongs to the nudix hydrolase family
CF389_RS11470	COG0697	spore germination
CF389_RS11475	COG4978	Transcriptional regulator
CF389_RS11475	COG0789	Transcriptional regulator
CF389_RS11480	COG0456	acetyltransferase
CF389_RS11485	COG0730	response to heat
CF389_RS11495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CF389_RS11500	COG2814	Major facilitator Superfamily
CF389_RS11510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CF389_RS11515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF389_RS11520	COG0488	(ABC) transporter
CF389_RS11525	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CF389_RS11530	COG2409	Drug exporters of the RND superfamily
CF389_RS11535	COG2197	response regulator
CF389_RS11540	COG4585	Histidine kinase
CF389_RS11550	COG5577	PFAM Coat F domain
CF389_RS11555	COG1063	alcohol dehydrogenase
CF389_RS11565	COG5577	PFAM Coat F domain
CF389_RS11570	COG1309	transcriptional regulator
CF389_RS11575	COG2814	Major facilitator Superfamily
CF389_RS11590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CF389_RS11600	COG0789	Transcriptional regulator
CF389_RS11605	COG1064	alcohol dehydrogenase
CF389_RS11630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CF389_RS11665	COG0277	FAD linked oxidase domain protein
CF389_RS11685	COG0477	Major facilitator Superfamily
CF389_RS11690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CF389_RS11700	COG1917	Cupin 2, conserved barrel domain protein
CF389_RS11700	COG2207	Transcriptional regulator
CF389_RS11705	COG1473	amidohydrolase
CF389_RS11710	COG0814	amino acid
CF389_RS11715	COG0251	oxidation-reduction process
CF389_RS11720	COG1802	Transcriptional regulator
CF389_RS11725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CF389_RS11735	COG3621	Patatin-like phospholipase
CF389_RS11750	COG1794	racemase activity, acting on amino acids and derivatives
CF389_RS11755	COG0730	response to heat
CF389_RS11760	COG0425	Belongs to the sulfur carrier protein TusA family
CF389_RS11765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CF389_RS11765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF389_RS11770	COG0425	Belongs to the sulfur carrier protein TusA family
CF389_RS11770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF389_RS11775	COG1054	Belongs to the UPF0176 family
CF389_RS11780	COG2210	Belongs to the sulfur carrier protein TusA family
CF389_RS11785	COG1937	Protein conserved in bacteria
CF389_RS11790	COG1329	Transcriptional regulator
CF389_RS11795	COG1278	Cold shock
CF389_RS11800	COG0457	Tetratricopeptide repeat
CF389_RS11805	COG2910	NAD(P)H-binding
CF389_RS11810	COG1959	2 iron, 2 sulfur cluster binding
CF389_RS11815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CF389_RS11825	COG2030	dehydratase
CF389_RS11835	COG1846	Transcriptional regulator
CF389_RS11840	COG1764	response to oxidative stress
CF389_RS11850	COG0477	Major facilitator Superfamily
CF389_RS11855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CF389_RS11870	COG2249	NAD(P)H dehydrogenase (quinone) activity
CF389_RS11920	COG2183	response to ionizing radiation
CF389_RS11925	COG2208	phosphoserine phosphatase activity
CF389_RS11930	COG1191	sigma factor activity
CF389_RS11940	COG1366	Belongs to the anti-sigma-factor antagonist family
CF389_RS11945	COG2208	phosphoserine phosphatase activity
CF389_RS11950	COG2172	sigma factor antagonist activity
CF389_RS11955	COG1366	Belongs to the anti-sigma-factor antagonist family
CF389_RS11960	COG1366	Belongs to the anti-sigma-factor antagonist family
CF389_RS11965	COG2337	Toxic component of a toxin-antitoxin (TA) module
CF389_RS11970	COG0864	Transcriptional regulator
CF389_RS11975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CF389_RS11980	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CF389_RS11990	COG0705	Rhomboid family
CF389_RS11995	COG3428	Bacterial PH domain
CF389_RS12000	COG3402	PFAM membrane-flanked domain
CF389_RS12005	COG0513	Belongs to the DEAD box helicase family
CF389_RS12010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CF389_RS12020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF389_RS12025	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CF389_RS12040	COG1960	acyl-CoA dehydrogenase activity
CF389_RS12050	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CF389_RS12055	COG1131	(ABC) transporter
CF389_RS12060	COG0628	permease
CF389_RS12065	COG1301	dicarboxylic acid transport
CF389_RS12070	COG4565	transcriptional regulatory protein
CF389_RS12075	COG3290	protein histidine kinase activity
CF389_RS12080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CF389_RS12085	COG3546	catalase activity
CF389_RS12090	COG2329	Antibiotic biosynthesis monooxygenase
CF389_RS12095	COG0662	Cupin 2, conserved barrel domain protein
CF389_RS12100	COG3729	General stress protein
CF389_RS12105	COG2217	Heavy metal translocating P-type atpase
CF389_RS12110	COG2076	Multidrug Resistance protein
CF389_RS12120	COG4876	unkown
CF389_RS12135	COG1914	H( )-stimulated, divalent metal cation uptake system
CF389_RS12165	COG0028	Belongs to the TPP enzyme family
CF389_RS12175	COG0531	amino acid
CF389_RS12185	COG1215	transferase activity, transferring glycosyl groups
CF389_RS12190	COG5298	Protein conserved in bacteria
CF389_RS12195	COG3706	GGDEF domain
CF389_RS12200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CF389_RS12205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CF389_RS12205	COG0551	DNA topoisomerase type I activity
CF389_RS12210	COG1522	sequence-specific DNA binding
CF389_RS12215	COG2814	Major facilitator Superfamily
CF389_RS12225	COG3871	stress protein (general stress protein 26)
CF389_RS12230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF389_RS12235	COG1917	Cupin 2, conserved barrel domain protein
CF389_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS12245	COG0318	PFAM AMP-dependent synthetase and ligase
CF389_RS12250	COG3711	transcriptional antiterminator
CF389_RS12255	COG4989	oxidoreductase activity
CF389_RS12260	COG0768	penicillin binding
CF389_RS12265	COG2329	Antibiotic biosynthesis monooxygenase
CF389_RS12275	COG2755	lipolytic protein G-D-S-L family
CF389_RS12280	COG1414	Transcriptional regulator
CF389_RS12285	COG1984	allophanate hydrolase subunit 2
CF389_RS12290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CF389_RS12300	COG1914	H( )-stimulated, divalent metal cation uptake system
CF389_RS12310	COG0561	phosphatase activity
CF389_RS12320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CF389_RS12330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF389_RS12335	COG2213	PTS system mannitol-specific
CF389_RS12345	COG1349	DNA-binding transcription factor activity
CF389_RS12350	COG2372	response to copper ion
CF389_RS12350	COG1276	copper resistance
CF389_RS12355	COG4549	nuclear export factor GLE1
CF389_RS12360	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS12365	COG4975	Glucose uptake
CF389_RS12370	COG1012	belongs to the aldehyde dehydrogenase family
CF389_RS12375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CF389_RS12380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CF389_RS12385	COG0640	Transcriptional regulator
CF389_RS12390	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CF389_RS12395	COG0778	Nitroreductase
CF389_RS12400	COG1309	transcriptional regulator
CF389_RS12405	COG2814	Major facilitator Superfamily
CF389_RS12410	COG4607	ABC-type enterochelin transport system periplasmic component
CF389_RS12415	COG4604	ABC transporter, ATP-binding protein
CF389_RS12420	COG4605	iron ion homeostasis
CF389_RS12425	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF389_RS12435	COG0527	aspartate kinase activity
CF389_RS12450	COG0457	Tetratricopeptide repeat
CF389_RS12455	COG3850	Histidine kinase
CF389_RS12455	COG5002	protein histidine kinase activity
CF389_RS12460	COG0745	RESPONSE REGULATOR receiver
CF389_RS12465	COG0577	efflux transmembrane transporter activity
CF389_RS12470	COG1136	(ABC) transporter
CF389_RS12475	COG2079	MmgE PrpD family protein
CF389_RS12480	COG1473	amidohydrolase
CF389_RS12485	COG1126	abc transporter atp-binding protein
CF389_RS12490	COG0765	amino acid transport
CF389_RS12495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF389_RS12500	COG0456	acetyltransferase
CF389_RS12505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CF389_RS12510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CF389_RS12520	COG0697	spore germination
CF389_RS12530	COG5434	Belongs to the glycosyl hydrolase 28 family
CF389_RS12535	COG3104	oligopeptide transport
CF389_RS12550	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CF389_RS12555	COG0163	prenyltransferase activity
CF389_RS12560	COG0583	DNA-binding transcription factor activity
CF389_RS12565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF389_RS12570	COG0765	amino acid transport
CF389_RS12575	COG1126	abc transporter atp-binding protein
CF389_RS12580	COG2364	Membrane
CF389_RS12595	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CF389_RS12600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS12605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS12610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS12615	COG1733	regulation of RNA biosynthetic process
CF389_RS12620	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CF389_RS12625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CF389_RS12630	COG3209	COG3209 Rhs family protein
CF389_RS12650	COG1714	RDD family
CF389_RS12655	COG1063	alcohol dehydrogenase
CF389_RS12660	COG0523	cobalamin synthesis protein
CF389_RS12665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CF389_RS12670	COG2146	nitrite reductase [NAD(P)H] activity
CF389_RS12675	COG1587	Uroporphyrinogen-III synthase
CF389_RS12675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CF389_RS12685	COG2508	Transcriptional regulator
CF389_RS12690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CF389_RS12695	COG1012	belongs to the aldehyde dehydrogenase family
CF389_RS12700	COG0506	proline dehydrogenase activity
CF389_RS12705	COG3541	Predicted nucleotidyltransferase
CF389_RS12710	COG3458	cephalosporin-C deacetylase activity
CF389_RS12715	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CF389_RS12720	COG2271	Major facilitator Superfamily
CF389_RS12730	COG1660	Displays ATPase and GTPase activities
CF389_RS12745	COG3665	Urea carboxylase-associated protein
CF389_RS12750	COG1113	amino acid transport
CF389_RS12755	COG3403	YqcI/YcgG family
CF389_RS12760	COG1280	lysine exporter protein (LysE YggA)
CF389_RS12765	COG1846	Transcriptional regulator
CF389_RS12770	COG2814	Major facilitator Superfamily
CF389_RS12780	COG0366	Alpha amylase catalytic
CF389_RS12790	COG1288	antiporter activity
CF389_RS12795	COG1473	amidohydrolase
CF389_RS12800	COG2113	Glycine betaine
CF389_RS12805	COG4176	ABC-type proline glycine betaine transport system permease component
CF389_RS12810	COG0517	IMP dehydrogenase activity
CF389_RS12810	COG4175	Glycine betaine
CF389_RS12815	COG0477	Major facilitator Superfamily
CF389_RS12820	COG3853	Toxic anion resistance protein (TelA)
CF389_RS12830	COG0861	Integral membrane protein TerC family
CF389_RS12835	COG2310	stress, protein
CF389_RS12840	COG2310	stress, protein
CF389_RS12845	COG2310	stress, protein
CF389_RS12850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CF389_RS12855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CF389_RS12860	COG1121	(ABC) transporter
CF389_RS12865	COG0803	Belongs to the bacterial solute-binding protein 9 family
CF389_RS12870	COG0366	Alpha amylase catalytic
CF389_RS12875	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS12880	COG0457	Tetratricopeptide repeat
CF389_RS12885	COG1876	peptidase activity
CF389_RS12890	COG1595	DNA-templated transcription, initiation
CF389_RS12895	COG1595	DNA-templated transcription, initiation
CF389_RS12905	COG0667	Aldo Keto reductase
CF389_RS12910	COG3012	SEC-C Motif Domain Protein
CF389_RS12910	COG1405	negative regulation of cell septum assembly
CF389_RS12915	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CF389_RS12920	COG0252	asparaginase activity
CF389_RS12925	COG1309	transcriptional regulator
CF389_RS12930	COG0477	Major facilitator Superfamily
CF389_RS12935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CF389_RS12945	COG0805	protein transport
CF389_RS12950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CF389_RS12955	COG3540	Alkaline phosphatase
CF389_RS12965	COG3773	Cell wall hydrolase
CF389_RS12985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF389_RS12990	COG2259	Doxx family
CF389_RS12995	COG0346	lactoylglutathione lyase activity
CF389_RS13000	COG0778	Nitroreductase
CF389_RS13005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CF389_RS13015	COG3173	Aminoglycoside phosphotransferase
CF389_RS13020	COG0784	Response regulator, receiver
CF389_RS13025	COG4191	Histidine kinase
CF389_RS13030	COG2066	Belongs to the glutaminase family
CF389_RS13035	COG1115	amino acid carrier protein
CF389_RS13040	COG2040	homocysteine
CF389_RS13045	COG0833	amino acid
CF389_RS13050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CF389_RS13055	COG1301	dicarboxylic acid transport
CF389_RS13070	COG0688	phosphatidylethanolamine metabolic process
CF389_RS13075	COG0586	Pfam SNARE associated Golgi protein
CF389_RS13080	COG1183	phosphatidylcholine synthase activity
CF389_RS13090	COG0371	Dehydrogenase
CF389_RS13105	COG3409	Peptidoglycan-binding domain 1 protein
CF389_RS13115	COG2368	4-hydroxyphenylacetate
CF389_RS13130	COG2271	Major facilitator Superfamily
CF389_RS13135	COG0584	glycerophosphoryl diester phosphodiesterase
CF389_RS13140	COG0531	amino acid
CF389_RS13180	COG1131	(ABC) transporter
CF389_RS13185	COG2197	response regulator
CF389_RS13190	COG4585	Histidine kinase
CF389_RS13195	COG1011	Hydrolase
CF389_RS13200	COG1113	amino acid transport
CF389_RS13205	COG1846	Transcriptional regulator
CF389_RS13210	COG1380	Effector of murein hydrolase LrgA
CF389_RS13215	COG1346	cytolysis
CF389_RS13260	COG4856	YbbR-like protein
CF389_RS13265	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CF389_RS13270	COG5662	AntiSigma factor
CF389_RS13275	COG1595	DNA-templated transcription, initiation
CF389_RS13305	COG1683	Conserved Protein
CF389_RS13310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF389_RS13320	COG1263	PTS System
CF389_RS13320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF389_RS13325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF389_RS13330	COG1472	Belongs to the glycosyl hydrolase 3 family
CF389_RS13335	COG3876	Protein conserved in bacteria
CF389_RS13340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CF389_RS13340	COG2207	Transcriptional regulator
CF389_RS13345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CF389_RS13350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF389_RS13355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF389_RS13360	COG2819	hydrolase of the alpha beta superfamily
CF389_RS13365	COG0385	Bile acid
CF389_RS13370	COG0659	secondary active sulfate transmembrane transporter activity
CF389_RS13385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CF389_RS13390	COG0738	Major facilitator superfamily
CF389_RS13450	COG0726	polysaccharide deacetylase
CF389_RS13455	COG2194	sulfuric ester hydrolase activity
CF389_RS13465	COG0489	protein tyrosine kinase activity
CF389_RS13470	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF389_RS13480	COG2318	DinB family
CF389_RS13485	COG2226	methyltransferase
CF389_RS13505	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CF389_RS13510	COG1122	ATPase activity
CF389_RS13515	COG1122	ATPase activity
CF389_RS13540	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CF389_RS13555	COG0024	Methionine aminopeptidase
CF389_RS13565	COG0201	protein transport
CF389_RS13675	COG0596	Alpha beta hydrolase
CF389_RS13700	COG1358	cellular component organization or biogenesis
CF389_RS13715	COG2813	Specifically methylates the guanine in position
CF389_RS13740	COG0250	Participates in transcription elongation, termination and antitermination
CF389_RS13745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CF389_RS13755	COG1595	DNA-templated transcription, initiation
CF389_RS13760	COG3688	RNA-binding protein containing a PIN domain
CF389_RS13765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CF389_RS13770	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CF389_RS13780	COG1045	serine acetyltransferase
CF389_RS13805	COG4956	integral membrane protein (PIN domain superfamily)
CF389_RS13810	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CF389_RS13815	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CF389_RS13820	COG0542	response to heat
CF389_RS13830	COG3880	PFAM UvrB UvrC protein
CF389_RS13835	COG4463	regulation of RNA biosynthetic process
CF389_RS13915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CF389_RS13920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CF389_RS13925	COG1396	sequence-specific DNA binding
CF389_RS13930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CF389_RS13935	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CF389_RS13940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CF389_RS13945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CF389_RS13950	COG0512	Glutamine amidotransferase of anthranilate synthase
CF389_RS13955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CF389_RS13960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CF389_RS13965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CF389_RS13980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CF389_RS13985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CF389_RS13990	COG0037	tRNA processing
CF389_RS13995	COG0515	serine threonine protein kinase
CF389_RS14000	COG2304	oxidoreductase activity
CF389_RS14005	COG2208	phosphoserine phosphatase activity
CF389_RS14020	COG1098	S1 RNA binding domain
CF389_RS14025	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CF389_RS14040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CF389_RS14045	COG3956	TIGRFAM MazG family protein
CF389_RS14050	COG2244	polysaccharide biosynthetic process
CF389_RS14055	COG2002	toxin-antitoxin pair type II binding
CF389_RS14060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CF389_RS14080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CF389_RS14095	COG0251	oxidation-reduction process
CF389_RS14100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CF389_RS14115	COG4466	Protein conserved in bacteria
CF389_RS14125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CF389_RS14130	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CF389_RS14135	COG3584	3D domain protein
CF389_RS14135	COG3583	domain protein
CF389_RS14140	COG0084	hydrolase, TatD family'
CF389_RS14145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CF389_RS14145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CF389_RS14150	COG2002	toxin-antitoxin pair type II binding
CF389_RS14155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CF389_RS14165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CF389_RS14175	COG1774	PSP1 C-terminal conserved region
CF389_RS14180	COG0470	DNA polymerase III
CF389_RS14185	COG1728	Protein conserved in bacteria
CF389_RS14190	COG3870	Protein conserved in bacteria
CF389_RS14200	COG1982	Orn Lys Arg decarboxylase major
CF389_RS14205	COG3853	Toxic anion resistance protein (TelA)
CF389_RS14210	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CF389_RS14260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CF389_RS14265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CF389_RS14275	COG0590	tRNA wobble adenosine to inosine editing
CF389_RS14280	COG1335	isochorismatase
CF389_RS14285	COG3858	chitin binding
CF389_RS14285	COG1388	LysM domain
CF389_RS14290	COG1428	Deoxynucleoside kinase
CF389_RS14295	COG1428	Deoxynucleoside kinase
CF389_RS14305	COG1929	Belongs to the glycerate kinase type-1 family
CF389_RS14325	COG1686	Belongs to the peptidase S11 family
CF389_RS14330	COG0517	IMP dehydrogenase activity
CF389_RS14330	COG0516	GMP reductase activity
CF389_RS14365	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CF389_RS14370	COG0187	DNA topoisomerase II activity
CF389_RS14385	COG2501	S4 domain
CF389_RS14390	COG0592	DNA-directed DNA polymerase activity
CF389_RS14410	COG0706	membrane insertase activity
CF389_RS14415	COG1847	R3H domain protein
CF389_RS14440	COG1192	Involved in chromosome partitioning
CF389_RS14445	COG1475	DNA binding
CF389_RS14460	COG3949	Membrane
CF389_RS14465	COG4481	Protein conserved in bacteria
CF389_RS14470	COG0243	molybdopterin cofactor binding
CF389_RS14475	COG0012	GTP binding
CF389_RS14485	COG0629	single-stranded DNA binding
CF389_RS14495	COG2169	Transcriptional regulator
CF389_RS14500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CF389_RS14505	COG0708	Exodeoxyribonuclease III
CF389_RS14510	COG1609	Transcriptional regulator
CF389_RS14515	COG0346	lactoylglutathione lyase activity
CF389_RS14520	COG2814	Major facilitator Superfamily
CF389_RS14520	COG0477	Major facilitator Superfamily
CF389_RS14525	COG1266	CAAX protease self-immunity
CF389_RS14530	COG1331	Highly conserved protein containing a thioredoxin domain
CF389_RS14540	COG1396	sequence-specific DNA binding
CF389_RS14545	COG1959	2 iron, 2 sulfur cluster binding
CF389_RS14555	COG0697	spore germination
CF389_RS14560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CF389_RS14570	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS14575	COG0583	DNA-binding transcription factor activity
CF389_RS14600	COG1846	Transcriptional regulator
CF389_RS14605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CF389_RS14610	COG1846	Transcriptional regulator
CF389_RS14615	COG0778	Nitroreductase
CF389_RS14625	COG2211	Major facilitator Superfamily
CF389_RS14630	COG2318	DinB family
CF389_RS14635	COG1802	Transcriptional regulator
CF389_RS14640	COG1621	beta-fructofuranosidase activity
CF389_RS14645	COG1621	beta-fructofuranosidase activity
CF389_RS14650	COG0697	spore germination
CF389_RS14660	COG1733	regulation of RNA biosynthetic process
CF389_RS14665	COG5577	PFAM Coat F domain
CF389_RS14675	COG4241	membrane
CF389_RS14680	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CF389_RS14690	COG0515	serine threonine protein kinase
CF389_RS14700	COG0438	transferase activity, transferring glycosyl groups
CF389_RS14705	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CF389_RS14715	COG0297	glycogen (starch) synthase activity
CF389_RS14720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CF389_RS14725	COG3093	addiction module antidote protein HigA
CF389_RS14740	COG0305	Participates in initiation and elongation during chromosome replication
CF389_RS14745	COG0346	lactoylglutathione lyase activity
CF389_RS14780	COG0745	RESPONSE REGULATOR receiver
CF389_RS14785	COG5002	protein histidine kinase activity
CF389_RS14790	COG4863	YycH protein
CF389_RS14795	COG4853	Protein conserved in bacteria
CF389_RS14800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CF389_RS14805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF389_RS14810	COG0745	RESPONSE REGULATOR receiver
CF389_RS14815	COG5002	protein histidine kinase activity
CF389_RS14820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CF389_RS14835	COG0488	(ABC) transporter
CF389_RS14845	COG3829	transcription factor binding
CF389_RS14850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CF389_RS14855	COG0833	amino acid
CF389_RS14860	COG0010	Belongs to the arginase family
CF389_RS14865	COG0457	Tetratricopeptide repeat
CF389_RS14870	COG0456	acetyltransferase
CF389_RS14875	COG0667	Aldo Keto reductase
CF389_RS14880	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CF389_RS14940	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CF389_RS14945	COG2068	MobA-Related Protein
CF389_RS14960	COG2080	2 iron, 2 sulfur cluster binding
CF389_RS14970	COG1113	amino acid transport
CF389_RS14975	COG3634	alkyl hydroperoxide reductase activity
CF389_RS14980	COG0450	alkyl hydroperoxide reductase
CF389_RS14990	COG1714	RDD family
CF389_RS14995	COG2814	Major facilitator Superfamily
CF389_RS15000	COG0640	Transcriptional regulator
CF389_RS15010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF389_RS15015	COG1012	belongs to the aldehyde dehydrogenase family
CF389_RS15020	COG1309	transcriptional regulator
CF389_RS15030	COG3239	Fatty acid desaturase
CF389_RS15035	COG4585	Histidine kinase
CF389_RS15040	COG2197	response regulator
CF389_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS15055	COG2814	Major facilitator Superfamily
CF389_RS15060	COG0667	Aldo Keto reductase
CF389_RS15065	COG1349	DNA-binding transcription factor activity
CF389_RS15095	COG2814	Major facilitator Superfamily
CF389_RS15105	COG1082	Xylose isomerase domain protein TIM barrel
CF389_RS15120	COG0745	RESPONSE REGULATOR receiver
CF389_RS15125	COG2205	protein histidine kinase activity
CF389_RS15130	COG1136	(ABC) transporter
CF389_RS15135	COG0577	efflux transmembrane transporter activity
CF389_RS15140	COG5294	Protein conserved in bacteria
CF389_RS15145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CF389_RS15175	COG0561	phosphatase activity
CF389_RS15180	COG2390	Transcriptional regulator
CF389_RS15190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CF389_RS15195	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CF389_RS15200	COG0833	amino acid
CF389_RS15205	COG0010	Belongs to the arginase family
CF389_RS15230	COG3507	Belongs to the glycosyl hydrolase 43 family
CF389_RS15235	COG0494	nUDIX hydrolase
CF389_RS15245	COG0589	response to stress
CF389_RS15250	COG0697	spore germination
CF389_RS15325	COG0513	Belongs to the DEAD box helicase family
CF389_RS15330	COG2270	Major facilitator Superfamily
CF389_RS15340	COG2273	Hydrolase Family 16
CF389_RS15345	COG2851	Citrate transporter
CF389_RS15350	COG0753	catalase activity
CF389_RS15350	COG0693	protein deglycase activity
CF389_RS15365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CF389_RS15370	COG0500	methyltransferase
CF389_RS15375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CF389_RS15380	COG4894	glucomannan catabolic process
CF389_RS15390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CF389_RS15400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CF389_RS15405	COG2508	Transcriptional regulator
CF389_RS15410	COG3842	ATPase activity
CF389_RS15415	COG0726	polysaccharide deacetylase
CF389_RS15420	COG3493	citrate carrier protein
CF389_RS15425	COG1271	oxidase subunit
CF389_RS15430	COG1294	oxidase, subunit
CF389_RS15435	COG4988	ABC transporter
CF389_RS15440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CF389_RS15445	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CF389_RS15450	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CF389_RS15455	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CF389_RS15460	COG0753	catalase activity
CF389_RS15470	COG1482	cell wall glycoprotein biosynthetic process
CF389_RS15475	COG1940	carbohydrate kinase activity
CF389_RS15480	COG2723	6-phospho-beta-galactosidase activity
CF389_RS15485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF389_RS15490	COG1447	Phosphotransferase system cellobiose-specific component IIA
CF389_RS15495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF389_RS15500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CF389_RS15505	COG0640	Transcriptional regulator
CF389_RS15515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF389_RS15520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF389_RS15535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF389_RS15535	COG3711	transcriptional antiterminator
CF389_RS15540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF389_RS15545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF389_RS15550	COG1447	Phosphotransferase system cellobiose-specific component IIA
CF389_RS15555	COG1486	melibiose metabolic process
CF389_RS15560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CF389_RS15565	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CF389_RS15575	COG1696	Membrane protein involved in D-alanine export
CF389_RS15595	COG1575	Belongs to the MenA family. Type 1 subfamily
CF389_RS15600	COG2357	RelA SpoT domain protein
CF389_RS15605	COG1442	glycosyl transferase family 8
CF389_RS15610	COG1404	Belongs to the peptidase S8 family
CF389_RS15615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF389_RS15620	COG0346	lactoylglutathione lyase activity
CF389_RS15625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CF389_RS15630	COG0789	Transcriptional regulator
CF389_RS15635	COG4895	conserved protein (DUF2196)
CF389_RS15640	COG1346	cytolysis
CF389_RS15650	COG0583	DNA-binding transcription factor activity
CF389_RS15670	COG2822	iron ion transport
CF389_RS15675	COG2837	iron assimilation
CF389_RS15680	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CF389_RS15700	COG1309	transcriptional regulator
CF389_RS15705	COG2246	polysaccharide biosynthetic process
CF389_RS15710	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CF389_RS15715	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CF389_RS15720	COG2261	transglycosylase associated protein
CF389_RS15725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CF389_RS15730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CF389_RS15750	COG0454	-acetyltransferase
CF389_RS15755	COG0772	Belongs to the SEDS family
CF389_RS15760	COG0778	Nitroreductase
CF389_RS15765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CF389_RS15770	COG1404	Belongs to the peptidase S8 family
CF389_RS15780	COG3711	transcriptional antiterminator
CF389_RS15785	COG1263	PTS System
CF389_RS15785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF389_RS15790	COG1621	beta-fructofuranosidase activity
CF389_RS15800	COG0351	phosphomethylpyrimidine kinase
CF389_RS15805	COG1695	Transcriptional regulator
CF389_RS15820	COG1216	Glycosyl transferase, family 2
CF389_RS15835	COG2233	PERMEase
CF389_RS15840	COG2363	Small membrane protein
CF389_RS15850	COG0463	Glycosyl transferase, family 2
CF389_RS15855	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CF389_RS15860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CF389_RS15865	COG0456	acetyltransferase
CF389_RS15870	COG2089	acid synthase
CF389_RS15875	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CF389_RS15880	COG3980	spore coat polysaccharide biosynthesis protein
CF389_RS15885	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CF389_RS15890	COG1088	dTDP-glucose 4,6-dehydratase activity
CF389_RS15895	COG1091	dTDP-4-dehydrorhamnose reductase activity
CF389_RS15900	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CF389_RS15910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CF389_RS15915	COG1012	belongs to the aldehyde dehydrogenase family
CF389_RS15920	COG4187	Peptidase family M20/M25/M40
CF389_RS15925	COG0833	amino acid
CF389_RS15930	COG2814	Major facilitator Superfamily
CF389_RS15935	COG2814	Major facilitator Superfamily
CF389_RS15965	COG0436	Aminotransferase
CF389_RS15970	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS15980	COG0280	phosphate acetyltransferase
CF389_RS15985	COG2855	membrane
CF389_RS15990	COG0583	DNA-binding transcription factor activity
CF389_RS16020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CF389_RS16025	COG1131	(ABC) transporter
CF389_RS16035	COG1695	Transcriptional regulator
CF389_RS16050	COG1078	dGTPase activity
CF389_RS16055	COG3465	dGTPase activity
CF389_RS16060	COG0531	amino acid
CF389_RS16070	COG1846	Transcriptional regulator
CF389_RS16075	COG1942	4-Oxalocrotonate Tautomerase
CF389_RS16080	COG1994	Peptidase M50
CF389_RS16095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CF389_RS16100	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CF389_RS16105	COG0010	Belongs to the arginase family
CF389_RS16150	COG0457	Tetratricopeptide repeat
CF389_RS16155	COG4506	Protein conserved in bacteria
CF389_RS16165	COG2223	nitrite transmembrane transporter activity
CF389_RS16170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF389_RS16180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF389_RS16185	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CF389_RS16190	COG1140	nitrate reductase beta subunit
CF389_RS16195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CF389_RS16200	COG2181	nitrate reductase activity
CF389_RS16210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CF389_RS16215	COG1132	(ABC) transporter
CF389_RS16230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CF389_RS16235	COG2181	nitrate reductase activity
CF389_RS16235	COG0247	lactate metabolic process
CF389_RS16250	COG4821	SIS domain
CF389_RS16255	COG2204	response regulator
CF389_RS16260	COG0191	fructose-bisphosphate aldolase activity
CF389_RS16270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CF389_RS16275	COG1494	fructose-1,6-bisphosphatase
CF389_RS16280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CF389_RS16295	COG0281	malic enzyme
CF389_RS16300	COG0679	Auxin Efflux Carrier
CF389_RS16305	COG0789	Transcriptional regulator
CF389_RS16310	COG0346	lactoylglutathione lyase activity
CF389_RS16315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CF389_RS16320	COG2890	protein-(glutamine-N5) methyltransferase activity
CF389_RS16340	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CF389_RS16345	COG0009	L-threonylcarbamoyladenylate synthase
CF389_RS16355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CF389_RS16360	COG0698	ribose 5-phosphate isomerase
CF389_RS16430	COG4836	Membrane
CF389_RS16440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CF389_RS16445	COG2385	sporulation resulting in formation of a cellular spore
CF389_RS16450	COG2304	oxidoreductase activity
CF389_RS16455	COG2304	oxidoreductase activity
CF389_RS16465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CF389_RS16475	COG0457	Tetratricopeptide repeat
CF389_RS16480	COG1994	Peptidase M50
CF389_RS16485	COG3237	CsbD-like
CF389_RS16490	COG0831	urea catabolic process
CF389_RS16505	COG1959	2 iron, 2 sulfur cluster binding
CF389_RS16515	COG0726	polysaccharide deacetylase
CF389_RS16525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CF389_RS16540	COG1247	-acetyltransferase
CF389_RS16545	COG0739	heme binding
CF389_RS16555	COG0671	phosphoesterase, PA-phosphatase related
CF389_RS16560	COG0772	Belongs to the SEDS family
CF389_RS16565	COG0347	Belongs to the P(II) protein family
CF389_RS16570	COG0004	ammonium transporteR
CF389_RS16575	COG1335	isochorismatase
CF389_RS16580	COG0477	Major facilitator Superfamily
CF389_RS16585	COG1953	Uracil, thiamine, allantoin
CF389_RS16590	COG2814	Major facilitator Superfamily
CF389_RS16595	COG1846	Transcriptional regulator
CF389_RS16600	COG1609	Transcriptional regulator
CF389_RS16605	COG1077	Cell shape determining protein MreB Mrl
CF389_RS16610	COG4786	Flagellar basal body rod
CF389_RS16615	COG4786	Flagellar basal body rod
CF389_RS16620	COG0457	Tetratricopeptide repeat
CF389_RS16645	COG0629	single-stranded DNA binding
CF389_RS16650	COG1349	DNA-binding transcription factor activity
CF389_RS16655	COG0561	phosphatase activity
CF389_RS16660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CF389_RS16665	COG4715	Zinc finger, swim domain protein
CF389_RS16680	COG3944	biosynthesis protein
CF389_RS16685	COG0489	protein tyrosine kinase activity
CF389_RS16690	COG4464	protein tyrosine phosphatase activity
CF389_RS16695	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CF389_RS16700	COG3878	Protein conserved in bacteria
CF389_RS16715	COG5444	nuclease activity
CF389_RS16750	COG5444	nuclease activity
CF389_RS16770	COG0583	DNA-binding transcription factor activity
CF389_RS16775	COG0655	NAD(P)H dehydrogenase (quinone) activity
CF389_RS16785	COG2059	Chromate
CF389_RS16790	COG2059	Chromate
CF389_RS16795	COG1522	sequence-specific DNA binding
CF389_RS16800	COG0405	Gamma-glutamyltransferase
CF389_RS16810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CF389_RS16820	COG5337	Spore coat protein CotH
CF389_RS16835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CF389_RS16840	COG0583	DNA-binding transcription factor activity
CF389_RS16845	COG0028	Belongs to the TPP enzyme family
CF389_RS16850	COG3527	Alpha-acetolactate decarboxylase
CF389_RS16855	COG2249	NAD(P)H dehydrogenase (quinone) activity
CF389_RS16860	COG3103	Sh3 type 3 domain protein
CF389_RS16865	COG1879	ABC-type sugar transport system periplasmic component
CF389_RS16870	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF389_RS16875	COG1129	ABC transporter
CF389_RS16885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF389_RS16890	COG1609	Transcriptional regulator
CF389_RS16900	COG0814	amino acid
CF389_RS16905	COG0697	spore germination
CF389_RS16915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CF389_RS16925	COG2843	Capsule synthesis protein
CF389_RS16935	COG0791	NLP P60 protein
CF389_RS16940	COG2433	Pfam Transposase IS66
CF389_RS16945	COG0561	phosphatase activity
CF389_RS16950	COG1316	TRANSCRIPTIONal
CF389_RS16955	COG2814	Major facilitator Superfamily
CF389_RS16960	COG1215	transferase activity, transferring glycosyl groups
CF389_RS16970	COG0814	amino acid
CF389_RS16975	COG0697	spore germination
CF389_RS16980	COG1482	cell wall glycoprotein biosynthetic process
CF389_RS16985	COG4193	domain, Protein
CF389_RS16990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CF389_RS16995	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CF389_RS17000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CF389_RS17010	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CF389_RS17015	COG1682	transport, permease protein
CF389_RS17020	COG1134	teichoic acid transport
CF389_RS17025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CF389_RS17030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CF389_RS17035	COG1316	TRANSCRIPTIONal
CF389_RS17045	COG2247	cell wall binding repeat
CF389_RS17045	COG2385	sporulation resulting in formation of a cellular spore
CF389_RS17050	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF389_RS17050	COG2247	cell wall binding repeat
CF389_RS17060	COG2244	polysaccharide biosynthetic process
CF389_RS17065	COG0438	transferase activity, transferring glycosyl groups
CF389_RS17065	COG0297	glycogen (starch) synthase activity
CF389_RS17070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CF389_RS17075	COG3307	-O-antigen
CF389_RS17080	COG3206	protein involved in exopolysaccharide biosynthesis
CF389_RS17085	COG1215	transferase activity, transferring glycosyl groups
CF389_RS17090	COG0438	transferase activity, transferring glycosyl groups
CF389_RS17095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CF389_RS17100	COG1316	TRANSCRIPTIONal
CF389_RS17105	COG1739	Uncharacterized protein family UPF0029
CF389_RS17110	COG4585	Histidine kinase
CF389_RS17115	COG2197	response regulator
CF389_RS17120	COG1307	EDD domain protein, DegV family
CF389_RS17125	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CF389_RS17135	COG1040	competence protein
CF389_RS17145	COG2747	anti-sigma28 factor FlgM
CF389_RS17150	COG3418	PFAM FlgN family protein
CF389_RS17155	COG4786	Flagellar basal body rod
CF389_RS17155	COG1256	bacterial-type flagellum assembly
CF389_RS17160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CF389_RS17180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CF389_RS17185	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CF389_RS17190	COG1516	flagellar protein fliS
CF389_RS17205	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CF389_RS17220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CF389_RS17225	COG2010	Cytochrome c
CF389_RS17230	COG2884	Cell division ATP-binding protein ftsE
CF389_RS17235	COG2177	Part of the ABC transporter FtsEX involved in
CF389_RS17240	COG3420	alginic acid biosynthetic process
CF389_RS17245	COG3409	Peptidoglycan-binding domain 1 protein
CF389_RS17245	COG0793	Belongs to the peptidase S41A family
CF389_RS17255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF389_RS17285	COG2814	Major facilitator Superfamily
CF389_RS17290	COG1309	transcriptional regulator
CF389_RS17295	COG0574	Belongs to the PEP-utilizing enzyme family
CF389_RS17295	COG3848	Pyruvate phosphate dikinase
CF389_RS17300	COG4897	Protein conserved in bacteria
CF389_RS17310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CF389_RS17325	COG3595	metallopeptidase activity
CF389_RS17330	COG1983	PspC domain protein
CF389_RS17335	COG1950	PFAM Membrane protein of
CF389_RS17340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CF389_RS17345	COG1309	transcriptional regulator
CF389_RS17350	COG2188	Transcriptional regulator
CF389_RS17360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CF389_RS17380	COG0110	maltose O-acetyltransferase activity
CF389_RS17385	COG4990	cell redox homeostasis
CF389_RS17400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CF389_RS17425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CF389_RS17425	COG0140	phosphoribosyl-ATP diphosphatase activity
CF389_RS17430	COG1132	(ABC) transporter
CF389_RS17440	COG0745	RESPONSE REGULATOR receiver
CF389_RS17445	COG5002	protein histidine kinase activity
CF389_RS17450	COG0457	Tetratricopeptide repeat
CF389_RS17455	COG0791	NLP P60 protein
CF389_RS17455	COG3883	PFAM NLP P60 protein
CF389_RS17460	COG0492	ferredoxin-NADP+ reductase activity
CF389_RS17465	COG1051	belongs to the nudix hydrolase family
CF389_RS17475	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CF389_RS17485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF389_RS17490	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CF389_RS17495	COG4290	ribonuclease
CF389_RS17500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CF389_RS17510	COG0288	reversible hydration of carbon dioxide
CF389_RS17515	COG0659	secondary active sulfate transmembrane transporter activity
CF389_RS17520	COG1694	Mazg nucleotide pyrophosphohydrolase
CF389_RS17525	COG1611	Belongs to the LOG family
CF389_RS17530	COG0477	Major facilitator Superfamily
CF389_RS17530	COG2814	Major facilitator Superfamily
CF389_RS17535	COG2828	Protein conserved in bacteria
CF389_RS17540	COG0583	DNA-binding transcription factor activity
CF389_RS17550	COG1609	Transcriptional regulator
CF389_RS17555	COG2223	nitrite transmembrane transporter activity
CF389_RS17610	COG3479	Phenolic acid decarboxylase
CF389_RS17615	COG0456	acetyltransferase
CF389_RS17620	COG2364	Membrane
CF389_RS17625	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CF389_RS17635	COG2272	Belongs to the type-B carboxylesterase lipase family
CF389_RS17640	COG1396	sequence-specific DNA binding
CF389_RS17645	COG3944	biosynthesis protein
CF389_RS17650	COG0489	protein tyrosine kinase activity
CF389_RS17655	COG1086	Polysaccharide biosynthesis protein
CF389_RS17660	COG0438	transferase activity, transferring glycosyl groups
CF389_RS17665	COG1215	transferase activity, transferring glycosyl groups
CF389_RS17670	COG0438	transferase activity, transferring glycosyl groups
CF389_RS17680	COG1216	Glycosyl transferase, family 2
CF389_RS17685	COG5039	Polysaccharide pyruvyl transferase
CF389_RS17690	COG1216	Glycosyl transferase, family 2
CF389_RS17695	COG2244	polysaccharide biosynthetic process
CF389_RS17700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CF389_RS17705	COG0110	maltose O-acetyltransferase activity
CF389_RS17710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CF389_RS17715	COG5039	Polysaccharide pyruvyl transferase
CF389_RS17725	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CF389_RS17730	COG1620	l-lactate permease
CF389_RS17735	COG2186	Transcriptional regulator
CF389_RS17740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CF389_RS17765	COG1070	Carbohydrate kinase
CF389_RS17770	COG1737	Transcriptional regulator
CF389_RS17775	COG1113	amino acid transport
CF389_RS17780	COG0697	spore germination
CF389_RS17785	COG0583	DNA-binding transcription factor activity
CF389_RS17795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CF389_RS17800	COG1609	Transcriptional regulator
CF389_RS17805	COG2814	Major facilitator Superfamily
CF389_RS17810	COG2390	Transcriptional regulator
CF389_RS17815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CF389_RS17825	COG0126	phosphoglycerate kinase activity
CF389_RS17845	COG2234	aminopeptidase activity
CF389_RS17855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CF389_RS17860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF389_RS17865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CF389_RS17880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CF389_RS17895	COG0456	acetyltransferase
CF389_RS17900	COG4640	response to antibiotic
CF389_RS17905	COG3064	Membrane
CF389_RS17910	COG2095	MarC family integral membrane protein
CF389_RS17915	COG1510	regulation of RNA biosynthetic process
CF389_RS17920	COG0517	IMP dehydrogenase activity
CF389_RS17920	COG1125	glycine betaine transport
CF389_RS17925	COG1174	glycine betaine transport
CF389_RS17930	COG1732	Glycine betaine
CF389_RS17935	COG1174	glycine betaine transport
CF389_RS17940	COG1510	regulation of RNA biosynthetic process
CF389_RS17945	COG1125	glycine betaine transport
CF389_RS17945	COG0517	IMP dehydrogenase activity
CF389_RS17950	COG1174	glycine betaine transport
CF389_RS17955	COG1732	Glycine betaine
CF389_RS17960	COG1174	glycine betaine transport
CF389_RS17965	COG1131	(ABC) transporter
CF389_RS17990	COG1733	regulation of RNA biosynthetic process
CF389_RS17995	COG1396	sequence-specific DNA binding
CF389_RS18000	COG1396	sequence-specific DNA binding
CF389_RS18005	COG1476	TRANSCRIPTIONal
CF389_RS18010	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CF389_RS18015	COG1647	Serine aminopeptidase, S33
CF389_RS18020	COG0557	exoribonuclease II activity
CF389_RS18045	COG2732	(Barnase) inhibitor
CF389_RS18050	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS18055	COG0583	DNA-binding transcription factor activity
CF389_RS18060	COG0454	-acetyltransferase
CF389_RS18065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF389_RS18070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF389_RS18075	COG0765	amino acid transport
CF389_RS18080	COG0765	amino acid transport
CF389_RS18085	COG1126	abc transporter atp-binding protein
CF389_RS18090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CF389_RS18095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CF389_RS18100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CF389_RS18110	COG0673	inositol 2-dehydrogenase activity
CF389_RS18115	COG1937	Protein conserved in bacteria
CF389_RS18120	COG2608	mercury ion transmembrane transporter activity
CF389_RS18125	COG2217	Heavy metal translocating P-type atpase
CF389_RS18130	COG2217	Heavy metal translocating P-type atpase
CF389_RS18135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CF389_RS18140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CF389_RS18150	COG2860	membrane
CF389_RS18155	COG3973	AAA domain
CF389_RS18160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CF389_RS18185	COG0656	L-ascorbic acid biosynthetic process
CF389_RS18190	COG0842	Transport permease protein
CF389_RS18200	COG1131	(ABC) transporter
CF389_RS18205	COG3850	Histidine kinase
CF389_RS18210	COG2197	response regulator
CF389_RS18215	COG4149	molybdate abc transporter
CF389_RS18220	COG0725	ABC transporter, periplasmic molybdate-binding protein
CF389_RS18225	COG1910	domain protein
CF389_RS18230	COG1368	sulfuric ester hydrolase activity
CF389_RS18235	COG1988	membrane-bound metal-dependent
CF389_RS18250	COG0531	amino acid
CF389_RS18255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CF389_RS18260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CF389_RS18265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF389_RS18270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF389_RS18275	COG1120	ATPase activity
CF389_RS18285	COG2140	Oxalate decarboxylase
CF389_RS18295	COG1191	sigma factor activity
CF389_RS18305	COG0745	RESPONSE REGULATOR receiver
CF389_RS18310	COG2205	protein histidine kinase activity
CF389_RS18315	COG3386	PFAM SMP-30 Gluconolaconase
CF389_RS18320	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS18325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CF389_RS18330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF389_RS18335	COG1120	ATPase activity
CF389_RS18340	COG2096	Adenosyltransferase
CF389_RS18345	COG2814	Major facilitator Superfamily
CF389_RS18350	COG4758	membrane
CF389_RS18355	COG1842	Phage shock protein A
CF389_RS18360	COG3595	metallopeptidase activity
CF389_RS18365	COG4758	membrane
CF389_RS18370	COG4585	Histidine kinase
CF389_RS18375	COG2197	response regulator
CF389_RS18385	COG0814	amino acid
CF389_RS18390	COG0697	spore germination
CF389_RS18400	COG0114	fumarate hydratase activity
CF389_RS18405	COG1309	transcriptional regulator
CF389_RS18415	COG2770	Histidine kinase
CF389_RS18415	COG2205	protein histidine kinase activity
CF389_RS18420	COG0745	RESPONSE REGULATOR receiver
CF389_RS18425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF389_RS18430	COG0783	Belongs to the Dps family
CF389_RS18435	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS18450	COG1120	ATPase activity
CF389_RS18470	COG0583	DNA-binding transcription factor activity
CF389_RS18475	COG0477	Major facilitator Superfamily
CF389_RS18480	COG1846	Transcriptional regulator
CF389_RS18485	COG5577	PFAM Coat F domain
CF389_RS18505	COG1250	3-hydroxyacyl-CoA dehydrogenase
CF389_RS18505	COG1024	Enoyl-CoA hydratase
CF389_RS18510	COG0183	Belongs to the thiolase family
CF389_RS18515	COG1960	acyl-CoA dehydrogenase activity
CF389_RS18520	COG1393	Belongs to the ArsC family
CF389_RS18535	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CF389_RS18540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF389_RS18550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CF389_RS18555	COG2011	ABC-type metal ion transport system permease component
CF389_RS18560	COG1464	Belongs to the NlpA lipoprotein family
CF389_RS18565	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CF389_RS18575	COG0396	ATPase activity
CF389_RS18580	COG0719	Fe-S assembly protein
CF389_RS18585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CF389_RS18590	COG0822	iron-sulfur transferase activity
CF389_RS18595	COG0719	Fe-S assembly protein
CF389_RS18600	COG3409	Peptidoglycan-binding domain 1 protein
CF389_RS18610	COG2226	methyltransferase
CF389_RS18615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CF389_RS18620	COG0322	excinuclease ABC activity
CF389_RS18635	COG0789	Transcriptional regulator
CF389_RS18640	COG2222	sugar isomerase
CF389_RS18645	COG1653	transport
CF389_RS18650	COG1175	transmembrane transport
CF389_RS18655	COG0395	ABC-type sugar transport system, permease component
CF389_RS18660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF389_RS18665	COG2188	Transcriptional regulator
CF389_RS18670	COG3842	ATPase activity
CF389_RS18675	COG2356	endonuclease I
CF389_RS18680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CF389_RS18685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CF389_RS18690	COG2814	Major facilitator Superfamily
CF389_RS18700	COG2508	Transcriptional regulator
CF389_RS18715	COG1801	Protein of unknown function DUF72
CF389_RS18720	COG0730	response to heat
CF389_RS18725	COG0737	Belongs to the 5'-nucleotidase family
CF389_RS18735	COG0739	heme binding
CF389_RS18750	COG4470	Protein conserved in bacteria
CF389_RS18755	COG2445	Protein of unknown function DUF86
CF389_RS18760	COG0647	UMP catabolic process
CF389_RS18765	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CF389_RS18770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CF389_RS18775	COG0460	homoserine dehydrogenase
CF389_RS18780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CF389_RS18790	COG1506	peptidase
CF389_RS18790	COG0823	Involved in the tonB-independent uptake of proteins
CF389_RS18790	COG4946	Tricorn protease homolog
CF389_RS18795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CF389_RS18800	COG4837	Protein of unknown function (DUF1462)
CF389_RS18805	COG1252	NADH dehydrogenase
CF389_RS18815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CF389_RS18825	COG0316	Belongs to the HesB IscA family
CF389_RS18830	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CF389_RS18855	COG1131	(ABC) transporter
CF389_RS18885	COG1252	NADH dehydrogenase
CF389_RS18895	COG3584	3D domain protein
CF389_RS18900	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CF389_RS18910	COG2056	Na+-H+ antiporter family
CF389_RS18915	COG1268	BioY protein
CF389_RS18920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CF389_RS18925	COG2819	hydrolase of the alpha beta superfamily
CF389_RS18930	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS18935	COG1169	isochorismate synthase
CF389_RS18940	COG1021	2,3-dihydroxybenzoate-AMP ligase
CF389_RS18945	COG3433	isochorismatase activity
CF389_RS18945	COG1535	isochorismatase
CF389_RS18950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF389_RS18955	COG3251	PFAM MbtH domain protein
CF389_RS18960	COG5634	Uncharacterized conserved protein (DUF2278)
CF389_RS18965	COG0686	Belongs to the AlaDH PNT family
CF389_RS18970	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CF389_RS18970	COG2508	Transcriptional regulator
CF389_RS18975	COG4842	Belongs to the WXG100 family
CF389_RS18980	COG5417	Belongs to the EsaB family
CF389_RS18985	COG4499	WXG100 protein secretion system (Wss), protein YukC
CF389_RS18990	COG1674	ftsk spoiiie
CF389_RS18990	COG0433	COG0433 Predicted ATPase
CF389_RS18995	COG1511	domain protein
CF389_RS19005	COG1028	Short-chain dehydrogenase reductase Sdr
CF389_RS19010	COG1418	mRNA catabolic process
CF389_RS19020	COG0628	permease
CF389_RS19035	COG5506	Protein of unknown function (DUF1694)
CF389_RS19040	COG1335	isochorismatase
CF389_RS19045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CF389_RS19050	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CF389_RS19065	COG0142	geranyltranstransferase activity
CF389_RS19075	COG4585	Histidine kinase
CF389_RS19080	COG2197	response regulator
CF389_RS19085	COG2050	protein possibly involved in aromatic compounds catabolism
CF389_RS19090	COG1320	monovalent cation:proton antiporter activity
CF389_RS19095	COG2212	antiporter activity
CF389_RS19100	COG1863	multisubunit Na H antiporter MnhE subunit
CF389_RS19105	COG0651	ATP synthesis coupled electron transport
CF389_RS19110	COG1006	Multisubunit Na H antiporter MnhC subunit
CF389_RS19115	COG2111	Na H antiporter
CF389_RS19120	COG2111	Na H antiporter
CF389_RS19120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CF389_RS19130	COG1079	Belongs to the binding-protein-dependent transport system permease family
CF389_RS19135	COG4603	Belongs to the binding-protein-dependent transport system permease family
CF389_RS19140	COG3845	ABC transporter
CF389_RS19145	COG1744	ABC transporter substrate-binding protein PnrA-like
CF389_RS19160	COG0457	Tetratricopeptide repeat
CF389_RS19210	COG0457	Tetratricopeptide repeat
CF389_RS19250	COG0457	Tetratricopeptide repeat
CF389_RS19255	COG0457	Tetratricopeptide repeat