locus-tag	class	description
AW02_RS00010	COG0592	DNA-directed DNA polymerase activity
AW02_RS00015	COG2501	S4 domain
AW02_RS00030	COG0187	DNA topoisomerase II activity
AW02_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW02_RS00070	COG0516	GMP reductase activity
AW02_RS00070	COG0517	IMP dehydrogenase activity
AW02_RS00075	COG1686	Belongs to the peptidase S11 family
AW02_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
AW02_RS00105	COG1428	Deoxynucleoside kinase
AW02_RS00110	COG1428	Deoxynucleoside kinase
AW02_RS00115	COG1388	LysM domain
AW02_RS00115	COG3858	chitin binding
AW02_RS00120	COG1335	isochorismatase
AW02_RS00125	COG0590	tRNA wobble adenosine to inosine editing
AW02_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AW02_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AW02_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AW02_RS00190	COG3853	Toxic anion resistance protein (TelA)
AW02_RS00195	COG1982	Orn Lys Arg decarboxylase major
AW02_RS00205	COG3870	Protein conserved in bacteria
AW02_RS00210	COG1728	Protein conserved in bacteria
AW02_RS00215	COG0470	DNA polymerase III
AW02_RS00220	COG1774	PSP1 C-terminal conserved region
AW02_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AW02_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AW02_RS00245	COG2002	toxin-antitoxin pair type II binding
AW02_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW02_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW02_RS00255	COG0084	hydrolase, TatD family'
AW02_RS00260	COG3583	domain protein
AW02_RS00260	COG3584	3D domain protein
AW02_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW02_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AW02_RS00280	COG4466	Protein conserved in bacteria
AW02_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW02_RS00300	COG0251	oxidation-reduction process
AW02_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AW02_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AW02_RS00340	COG2002	toxin-antitoxin pair type II binding
AW02_RS00345	COG2244	polysaccharide biosynthetic process
AW02_RS00350	COG3956	TIGRFAM MazG family protein
AW02_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AW02_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AW02_RS00375	COG1098	S1 RNA binding domain
AW02_RS00390	COG2208	phosphoserine phosphatase activity
AW02_RS00395	COG2304	oxidoreductase activity
AW02_RS00400	COG0515	serine threonine protein kinase
AW02_RS00405	COG0037	tRNA processing
AW02_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AW02_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AW02_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW02_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW02_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW02_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
AW02_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW02_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW02_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AW02_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AW02_RS00470	COG1396	sequence-specific DNA binding
AW02_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW02_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AW02_RS00560	COG4463	regulation of RNA biosynthetic process
AW02_RS00565	COG3880	PFAM UvrB UvrC protein
AW02_RS00575	COG0542	response to heat
AW02_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AW02_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AW02_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
AW02_RS00610	COG1045	serine acetyltransferase
AW02_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AW02_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW02_RS00630	COG3688	RNA-binding protein containing a PIN domain
AW02_RS00635	COG1595	DNA-templated transcription, initiation
AW02_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW02_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
AW02_RS00675	COG2813	Specifically methylates the guanine in position
AW02_RS00690	COG1358	cellular component organization or biogenesis
AW02_RS00715	COG0596	Alpha beta hydrolase
AW02_RS00820	COG0201	protein transport
AW02_RS00830	COG0024	Methionine aminopeptidase
AW02_RS00840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AW02_RS00865	COG1122	ATPase activity
AW02_RS00870	COG1122	ATPase activity
AW02_RS00875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW02_RS00895	COG2226	methyltransferase
AW02_RS00900	COG2318	DinB family
AW02_RS00910	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW02_RS00915	COG0489	protein tyrosine kinase activity
AW02_RS00925	COG2194	sulfuric ester hydrolase activity
AW02_RS00930	COG0726	polysaccharide deacetylase
AW02_RS00950	COG0738	Major facilitator superfamily
AW02_RS00955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW02_RS00970	COG0659	secondary active sulfate transmembrane transporter activity
AW02_RS00975	COG0385	Bile acid
AW02_RS00980	COG2819	hydrolase of the alpha beta superfamily
AW02_RS00985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW02_RS00990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW02_RS00995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW02_RS01000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW02_RS01000	COG2207	Transcriptional regulator
AW02_RS01005	COG3876	Protein conserved in bacteria
AW02_RS01010	COG1472	Belongs to the glycosyl hydrolase 3 family
AW02_RS01015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW02_RS01020	COG1263	PTS System
AW02_RS01020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW02_RS01030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW02_RS01035	COG1683	Conserved Protein
AW02_RS01065	COG1595	DNA-templated transcription, initiation
AW02_RS01070	COG5662	AntiSigma factor
AW02_RS01075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW02_RS01080	COG4856	YbbR-like protein
AW02_RS01120	COG1346	cytolysis
AW02_RS01125	COG1380	Effector of murein hydrolase LrgA
AW02_RS01130	COG1846	Transcriptional regulator
AW02_RS01135	COG1113	amino acid transport
AW02_RS01140	COG1011	Hydrolase
AW02_RS01145	COG4585	Histidine kinase
AW02_RS01150	COG2197	response regulator
AW02_RS01155	COG1131	(ABC) transporter
AW02_RS01175	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AW02_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS01190	COG3321	synthase
AW02_RS01190	COG4221	oxidoreductase activity
AW02_RS01190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS01195	COG3321	synthase
AW02_RS01195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS01195	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS01195	COG0300	oxidoreductase activity
AW02_RS01235	COG0531	amino acid
AW02_RS01240	COG0584	glycerophosphoryl diester phosphodiesterase
AW02_RS01245	COG2271	Major facilitator Superfamily
AW02_RS01255	COG2368	4-hydroxyphenylacetate
AW02_RS01265	COG3409	Peptidoglycan-binding domain 1 protein
AW02_RS01280	COG0371	Dehydrogenase
AW02_RS01290	COG1183	phosphatidylcholine synthase activity
AW02_RS01295	COG0586	Pfam SNARE associated Golgi protein
AW02_RS01300	COG0688	phosphatidylethanolamine metabolic process
AW02_RS01315	COG1301	dicarboxylic acid transport
AW02_RS01320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW02_RS01325	COG0833	amino acid
AW02_RS01330	COG2040	homocysteine
AW02_RS01335	COG1115	amino acid carrier protein
AW02_RS01340	COG2066	Belongs to the glutaminase family
AW02_RS01345	COG4191	Histidine kinase
AW02_RS01350	COG0784	Response regulator, receiver
AW02_RS01355	COG3173	Aminoglycoside phosphotransferase
AW02_RS01365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW02_RS01370	COG0778	Nitroreductase
AW02_RS01375	COG0346	lactoylglutathione lyase activity
AW02_RS01380	COG2259	Doxx family
AW02_RS01385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW02_RS01395	COG3773	Cell wall hydrolase
AW02_RS01400	COG3540	Alkaline phosphatase
AW02_RS01405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW02_RS01410	COG0805	protein transport
AW02_RS01420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW02_RS01425	COG0477	Major facilitator Superfamily
AW02_RS01430	COG1309	transcriptional regulator
AW02_RS01435	COG0252	asparaginase activity
AW02_RS01440	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AW02_RS01445	COG1405	negative regulation of cell septum assembly
AW02_RS01445	COG3012	SEC-C Motif Domain Protein
AW02_RS01450	COG0667	Aldo Keto reductase
AW02_RS01460	COG1595	DNA-templated transcription, initiation
AW02_RS01465	COG1595	DNA-templated transcription, initiation
AW02_RS01470	COG1876	peptidase activity
AW02_RS01475	COG0457	Tetratricopeptide repeat
AW02_RS01480	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS01485	COG0366	Alpha amylase catalytic
AW02_RS01490	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW02_RS01495	COG1121	(ABC) transporter
AW02_RS01500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW02_RS01505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW02_RS01510	COG2310	stress, protein
AW02_RS01515	COG2310	stress, protein
AW02_RS01520	COG2310	stress, protein
AW02_RS01525	COG0861	Integral membrane protein TerC family
AW02_RS01535	COG3853	Toxic anion resistance protein (TelA)
AW02_RS01540	COG0477	Major facilitator Superfamily
AW02_RS01545	COG0517	IMP dehydrogenase activity
AW02_RS01545	COG4175	Glycine betaine
AW02_RS01550	COG4176	ABC-type proline glycine betaine transport system permease component
AW02_RS01555	COG2113	Glycine betaine
AW02_RS01560	COG1473	amidohydrolase
AW02_RS01565	COG1288	antiporter activity
AW02_RS01575	COG0366	Alpha amylase catalytic
AW02_RS01585	COG2814	Major facilitator Superfamily
AW02_RS01590	COG1846	Transcriptional regulator
AW02_RS01595	COG1280	lysine exporter protein (LysE YggA)
AW02_RS01600	COG3403	YqcI/YcgG family
AW02_RS01605	COG1113	amino acid transport
AW02_RS01610	COG3665	Urea carboxylase-associated protein
AW02_RS01625	COG1660	Displays ATPase and GTPase activities
AW02_RS01635	COG2271	Major facilitator Superfamily
AW02_RS01640	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AW02_RS01645	COG3458	cephalosporin-C deacetylase activity
AW02_RS01650	COG3541	Predicted nucleotidyltransferase
AW02_RS01655	COG0506	proline dehydrogenase activity
AW02_RS01660	COG1012	belongs to the aldehyde dehydrogenase family
AW02_RS01665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW02_RS01670	COG2508	Transcriptional regulator
AW02_RS01680	COG1587	Uroporphyrinogen-III synthase
AW02_RS01680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW02_RS01685	COG2146	nitrite reductase [NAD(P)H] activity
AW02_RS01690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW02_RS01695	COG0523	cobalamin synthesis protein
AW02_RS01700	COG1063	alcohol dehydrogenase
AW02_RS01705	COG1714	RDD family
AW02_RS01715	COG2723	6-phospho-beta-galactosidase activity
AW02_RS01725	COG3209	COG3209 Rhs family protein
AW02_RS01730	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AW02_RS01735	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AW02_RS01740	COG1733	regulation of RNA biosynthetic process
AW02_RS01750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS01755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS01760	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AW02_RS01775	COG2364	Membrane
AW02_RS01780	COG1126	abc transporter atp-binding protein
AW02_RS01785	COG0765	amino acid transport
AW02_RS01790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW02_RS01795	COG0583	DNA-binding transcription factor activity
AW02_RS01800	COG0163	prenyltransferase activity
AW02_RS01805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AW02_RS01820	COG3104	oligopeptide transport
AW02_RS01825	COG5434	Belongs to the glycosyl hydrolase 28 family
AW02_RS01835	COG0697	spore germination
AW02_RS01845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AW02_RS01850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW02_RS01855	COG0456	acetyltransferase
AW02_RS01860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW02_RS01865	COG0765	amino acid transport
AW02_RS01870	COG1126	abc transporter atp-binding protein
AW02_RS01875	COG1473	amidohydrolase
AW02_RS01880	COG2079	MmgE PrpD family protein
AW02_RS01885	COG1136	(ABC) transporter
AW02_RS01890	COG0577	efflux transmembrane transporter activity
AW02_RS01895	COG0745	RESPONSE REGULATOR receiver
AW02_RS01900	COG3850	Histidine kinase
AW02_RS01900	COG5002	protein histidine kinase activity
AW02_RS01905	COG0457	Tetratricopeptide repeat
AW02_RS01915	COG0527	aspartate kinase activity
AW02_RS01920	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW02_RS01925	COG4605	iron ion homeostasis
AW02_RS01930	COG4604	ABC transporter, ATP-binding protein
AW02_RS01935	COG4607	ABC-type enterochelin transport system periplasmic component
AW02_RS01940	COG2814	Major facilitator Superfamily
AW02_RS01945	COG1309	transcriptional regulator
AW02_RS01950	COG0778	Nitroreductase
AW02_RS01955	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW02_RS01960	COG0640	Transcriptional regulator
AW02_RS01965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW02_RS01970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW02_RS01975	COG1012	belongs to the aldehyde dehydrogenase family
AW02_RS01980	COG4975	Glucose uptake
AW02_RS01985	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS01990	COG4549	nuclear export factor GLE1
AW02_RS01995	COG2372	response to copper ion
AW02_RS01995	COG1276	copper resistance
AW02_RS02000	COG1349	DNA-binding transcription factor activity
AW02_RS02010	COG2213	PTS system mannitol-specific
AW02_RS02015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW02_RS02025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW02_RS02030	COG0561	phosphatase activity
AW02_RS02040	COG1914	H( )-stimulated, divalent metal cation uptake system
AW02_RS02050	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AW02_RS02055	COG1984	allophanate hydrolase subunit 2
AW02_RS02060	COG1414	Transcriptional regulator
AW02_RS02065	COG2755	lipolytic protein G-D-S-L family
AW02_RS02075	COG2329	Antibiotic biosynthesis monooxygenase
AW02_RS02080	COG0768	penicillin binding
AW02_RS02085	COG4989	oxidoreductase activity
AW02_RS02090	COG3711	transcriptional antiterminator
AW02_RS02095	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS02100	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS02105	COG1917	Cupin 2, conserved barrel domain protein
AW02_RS02110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW02_RS02115	COG3871	stress protein (general stress protein 26)
AW02_RS02125	COG2814	Major facilitator Superfamily
AW02_RS02130	COG1522	sequence-specific DNA binding
AW02_RS02135	COG0551	DNA topoisomerase type I activity
AW02_RS02135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW02_RS02140	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AW02_RS02145	COG3706	GGDEF domain
AW02_RS02150	COG5298	Protein conserved in bacteria
AW02_RS02155	COG1215	transferase activity, transferring glycosyl groups
AW02_RS02165	COG0531	amino acid
AW02_RS02170	COG0494	nUDIX hydrolase
AW02_RS02175	COG0028	Belongs to the TPP enzyme family
AW02_RS02205	COG1914	H( )-stimulated, divalent metal cation uptake system
AW02_RS02220	COG4876	unkown
AW02_RS02230	COG2076	Multidrug Resistance protein
AW02_RS02235	COG2217	Heavy metal translocating P-type atpase
AW02_RS02240	COG3729	General stress protein
AW02_RS02245	COG0662	Cupin 2, conserved barrel domain protein
AW02_RS02250	COG2329	Antibiotic biosynthesis monooxygenase
AW02_RS02255	COG3546	catalase activity
AW02_RS02260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AW02_RS02265	COG3290	protein histidine kinase activity
AW02_RS02270	COG4565	transcriptional regulatory protein
AW02_RS02275	COG1301	dicarboxylic acid transport
AW02_RS02280	COG0628	permease
AW02_RS02285	COG1131	(ABC) transporter
AW02_RS02290	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW02_RS02300	COG1960	acyl-CoA dehydrogenase activity
AW02_RS02310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW02_RS02315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW02_RS02325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW02_RS02330	COG0513	Belongs to the DEAD box helicase family
AW02_RS02335	COG3402	PFAM membrane-flanked domain
AW02_RS02340	COG3428	Bacterial PH domain
AW02_RS02345	COG0705	Rhomboid family
AW02_RS02355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AW02_RS02360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW02_RS02365	COG0864	Transcriptional regulator
AW02_RS02370	COG2337	Toxic component of a toxin-antitoxin (TA) module
AW02_RS02375	COG1366	Belongs to the anti-sigma-factor antagonist family
AW02_RS02380	COG1366	Belongs to the anti-sigma-factor antagonist family
AW02_RS02385	COG2172	sigma factor antagonist activity
AW02_RS02390	COG2208	phosphoserine phosphatase activity
AW02_RS02395	COG1366	Belongs to the anti-sigma-factor antagonist family
AW02_RS02405	COG1191	sigma factor activity
AW02_RS02410	COG2208	phosphoserine phosphatase activity
AW02_RS02415	COG2183	response to ionizing radiation
AW02_RS02460	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW02_RS02470	COG0477	Major facilitator Superfamily
AW02_RS02480	COG1764	response to oxidative stress
AW02_RS02485	COG1846	Transcriptional regulator
AW02_RS02490	COG1959	2 iron, 2 sulfur cluster binding
AW02_RS02495	COG2910	NAD(P)H-binding
AW02_RS02500	COG1278	Cold shock
AW02_RS02505	COG1329	Transcriptional regulator
AW02_RS02510	COG1937	Protein conserved in bacteria
AW02_RS02515	COG2210	Belongs to the sulfur carrier protein TusA family
AW02_RS02525	COG0425	Belongs to the sulfur carrier protein TusA family
AW02_RS02525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW02_RS02530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW02_RS02530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW02_RS02535	COG0425	Belongs to the sulfur carrier protein TusA family
AW02_RS02540	COG0730	response to heat
AW02_RS02545	COG1794	racemase activity, acting on amino acids and derivatives
AW02_RS02560	COG3621	Patatin-like phospholipase
AW02_RS02570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AW02_RS02575	COG1802	Transcriptional regulator
AW02_RS02580	COG0251	oxidation-reduction process
AW02_RS02585	COG0814	amino acid
AW02_RS02590	COG1473	amidohydrolase
AW02_RS02595	COG2207	Transcriptional regulator
AW02_RS02595	COG1917	Cupin 2, conserved barrel domain protein
AW02_RS02605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW02_RS02610	COG0477	Major facilitator Superfamily
AW02_RS02630	COG0277	FAD linked oxidase domain protein
AW02_RS02665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW02_RS02690	COG1064	alcohol dehydrogenase
AW02_RS02695	COG0789	Transcriptional regulator
AW02_RS02705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW02_RS02720	COG2814	Major facilitator Superfamily
AW02_RS02725	COG1309	transcriptional regulator
AW02_RS02730	COG5577	PFAM Coat F domain
AW02_RS02740	COG1063	alcohol dehydrogenase
AW02_RS02745	COG5577	PFAM Coat F domain
AW02_RS02755	COG4585	Histidine kinase
AW02_RS02760	COG2197	response regulator
AW02_RS02765	COG2409	Drug exporters of the RND superfamily
AW02_RS02770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AW02_RS02775	COG0488	(ABC) transporter
AW02_RS02780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW02_RS02785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW02_RS02795	COG2814	Major facilitator Superfamily
AW02_RS02800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW02_RS02810	COG0730	response to heat
AW02_RS02815	COG0456	acetyltransferase
AW02_RS02820	COG0789	Transcriptional regulator
AW02_RS02820	COG4978	Transcriptional regulator
AW02_RS02825	COG0697	spore germination
AW02_RS02830	COG1051	belongs to the nudix hydrolase family
AW02_RS02835	COG2226	methyltransferase
AW02_RS02840	COG0473	3-isopropylmalate dehydrogenase activity
AW02_RS02845	COG1802	Transcriptional regulator
AW02_RS02850	COG1819	glycosyl
AW02_RS02865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW02_RS02870	COG1388	LysM domain
AW02_RS02875	COG2814	Major facilitator Superfamily
AW02_RS02880	COG2188	Transcriptional regulator
AW02_RS02885	COG2186	Transcriptional regulator
AW02_RS02890	COG2807	transmembrane transport
AW02_RS02895	COG2076	Multidrug Resistance protein
AW02_RS02900	COG2076	Multidrug Resistance protein
AW02_RS02905	COG1309	transcriptional regulator
AW02_RS02910	COG0531	amino acid
AW02_RS02920	COG3832	glyoxalase III activity
AW02_RS02925	COG0604	alcohol dehydrogenase
AW02_RS02930	COG2814	Major facilitator Superfamily
AW02_RS02970	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AW02_RS02975	COG0802	atpase or kinase
AW02_RS02980	COG1214	PFAM Peptidase M22, glycoprotease
AW02_RS02985	COG0456	acetyltransferase
AW02_RS02990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AW02_RS02995	COG0488	(ABC) transporter
AW02_RS03010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW02_RS03015	COG0805	protein transport
AW02_RS03025	COG1266	CAAX protease self-immunity
AW02_RS03045	COG0457	Tetratricopeptide repeat
AW02_RS03050	COG1063	alcohol dehydrogenase
AW02_RS03055	COG2211	Major facilitator Superfamily
AW02_RS03060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW02_RS03070	COG1842	Phage shock protein A
AW02_RS03075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW02_RS03080	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AW02_RS03085	COG4260	virion core protein, lumpy skin disease virus
AW02_RS03090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AW02_RS03090	COG2755	lipolytic protein G-D-S-L family
AW02_RS03100	COG1595	DNA-templated transcription, initiation
AW02_RS03105	COG1063	alcohol dehydrogenase
AW02_RS03110	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AW02_RS03115	COG0823	Involved in the tonB-independent uptake of proteins
AW02_RS03130	COG2132	Multicopper oxidase
AW02_RS03135	COG1113	amino acid transport
AW02_RS03140	COG0714	Associated with various cellular activities
AW02_RS03145	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AW02_RS03150	COG1305	Transglutaminase-like
AW02_RS03170	COG2252	PERMEase
AW02_RS03175	COG3064	Membrane
AW02_RS03190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AW02_RS03195	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AW02_RS03200	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AW02_RS03205	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AW02_RS03210	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AW02_RS03225	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AW02_RS03235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AW02_RS03240	COG0138	bifunctional purine biosynthesis protein purh
AW02_RS03245	COG0151	Belongs to the GarS family
AW02_RS03255	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW02_RS03260	COG1470	cell adhesion involved in biofilm formation
AW02_RS03265	COG4496	protein, YerC YecD
AW02_RS03270	COG0069	glutamate synthase activity
AW02_RS03285	COG0210	DNA helicase
AW02_RS03295	COG4851	CamS sex pheromone cAM373 precursor
AW02_RS03300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW02_RS03305	COG1285	pathogenesis
AW02_RS03310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW02_RS03330	COG1309	transcriptional regulator
AW02_RS03335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW02_RS03340	COG1597	lipid kinase activity
AW02_RS03345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW02_RS03355	COG1131	(ABC) transporter
AW02_RS03375	COG5444	nuclease activity
AW02_RS03410	COG3546	catalase activity
AW02_RS03415	COG0454	-acetyltransferase
AW02_RS03425	COG2323	membrane
AW02_RS03430	COG2329	Antibiotic biosynthesis monooxygenase
AW02_RS03435	COG0346	lactoylglutathione lyase activity
AW02_RS03440	COG1366	Belongs to the anti-sigma-factor antagonist family
AW02_RS03445	COG0196	riboflavin kinase activity
AW02_RS03450	COG0670	Belongs to the BI1 family
AW02_RS03455	COG1846	Transcriptional regulator
AW02_RS03460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW02_RS03470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW02_RS03470	COG2124	cytochrome p450
AW02_RS03480	COG1368	sulfuric ester hydrolase activity
AW02_RS03485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AW02_RS03490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW02_RS03495	COG1442	glycosyl transferase family 8
AW02_RS03500	COG1216	Glycosyl transferase, family 2
AW02_RS03505	COG1442	glycosyl transferase family 8
AW02_RS03510	COG2223	nitrite transmembrane transporter activity
AW02_RS03515	COG0531	amino acid
AW02_RS03520	COG1012	belongs to the aldehyde dehydrogenase family
AW02_RS03525	COG0840	transmembrane signaling receptor activity
AW02_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS03535	COG0463	Glycosyl transferase, family 2
AW02_RS03535	COG0457	Tetratricopeptide repeat
AW02_RS03540	COG0488	(ABC) transporter
AW02_RS03545	COG0789	Transcriptional regulator
AW02_RS03550	COG2814	Major facilitator Superfamily
AW02_RS03555	COG0488	(ABC) transporter
AW02_RS03560	COG0513	Belongs to the DEAD box helicase family
AW02_RS03570	COG2130	NADP-dependent
AW02_RS03585	COG3866	Pectate lyase
AW02_RS03590	COG0471	metal ion transport
AW02_RS03610	COG2972	Histidine kinase
AW02_RS03610	COG0745	RESPONSE REGULATOR receiver
AW02_RS03615	COG3279	Response regulator of the LytR AlgR family
AW02_RS03625	COG3764	Sortase (surface protein transpeptidase)
AW02_RS03630	COG3290	protein histidine kinase activity
AW02_RS03635	COG4565	transcriptional regulatory protein
AW02_RS03640	COG3181	Tripartite tricarboxylate transporter family receptor
AW02_RS03645	COG2851	Citrate transporter
AW02_RS03650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW02_RS03655	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AW02_RS03665	COG2258	MOSC domain
AW02_RS03675	COG0024	Methionine aminopeptidase
AW02_RS03680	COG1263	PTS System
AW02_RS03680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW02_RS03690	COG1368	sulfuric ester hydrolase activity
AW02_RS03700	COG0071	Belongs to the small heat shock protein (HSP20) family
AW02_RS03715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW02_RS03715	COG1263	PTS System
AW02_RS03720	COG0366	Alpha amylase catalytic
AW02_RS03725	COG2188	Transcriptional regulator
AW02_RS03730	COG0778	Nitroreductase
AW02_RS03745	COG0737	Belongs to the 5'-nucleotidase family
AW02_RS03750	COG0693	protein deglycase activity
AW02_RS03755	COG1609	Transcriptional regulator
AW02_RS03770	COG2814	Major facilitator Superfamily
AW02_RS03780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW02_RS03785	COG4980	gas vesicle protein
AW02_RS03790	COG1295	ribonuclease BN
AW02_RS03795	COG0477	Major facilitator Superfamily
AW02_RS03800	COG0387	Pfam Sodium calcium exchanger
AW02_RS03810	COG0668	transmembrane transport
AW02_RS03815	COG0535	radical SAM domain protein
AW02_RS03825	COG0726	polysaccharide deacetylase
AW02_RS03830	COG2084	Dehydrogenase
AW02_RS03840	COG0598	Magnesium transport protein CorA
AW02_RS03845	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW02_RS03850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW02_RS03860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW02_RS03865	COG4637	Psort location Cytoplasmic, score
AW02_RS03870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW02_RS03875	COG0022	dehydrogenase e1 component
AW02_RS03880	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW02_RS03885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW02_RS03890	COG3284	Transcriptional regulator
AW02_RS03900	COG1486	melibiose metabolic process
AW02_RS03905	COG1737	Transcriptional regulator
AW02_RS03910	COG1263	PTS System
AW02_RS03910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW02_RS03915	COG1132	(ABC) transporter
AW02_RS03920	COG1132	(ABC) transporter
AW02_RS03925	COG2259	Doxx family
AW02_RS03930	COG2514	catechol 2,3-dioxygenase activity
AW02_RS03940	COG1695	Transcriptional regulator
AW02_RS03945	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW02_RS03950	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AW02_RS03955	COG0574	Belongs to the PEP-utilizing enzyme family
AW02_RS03955	COG3848	Pyruvate phosphate dikinase
AW02_RS03960	COG2732	(Barnase) inhibitor
AW02_RS03965	COG2318	DinB family
AW02_RS03970	COG2814	Major facilitator Superfamily
AW02_RS03975	COG1846	Transcriptional regulator
AW02_RS03980	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AW02_RS03980	COG0392	lysyltransferase activity
AW02_RS03985	COG0384	phenazine biosynthesis protein PhzF
AW02_RS03990	COG0778	Nitroreductase
AW02_RS04000	COG1090	epimerase
AW02_RS04015	COG2814	Major facilitator Superfamily
AW02_RS04025	COG3591	Belongs to the peptidase S1B family
AW02_RS04040	COG3103	Sh3 type 3 domain protein
AW02_RS04045	COG5658	integral membrane protein
AW02_RS04050	COG0596	Alpha beta hydrolase
AW02_RS04055	COG0463	Glycosyl transferase, family 2
AW02_RS04060	COG4485	Bacterial membrane protein, YfhO
AW02_RS04065	COG1988	membrane-bound metal-dependent
AW02_RS04070	COG1194	a g-specific adenine glycosylase
AW02_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS04100	COG1132	(ABC) transporter
AW02_RS04105	COG4129	membrane
AW02_RS04115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AW02_RS04120	COG0735	belongs to the Fur family
AW02_RS04225	COG4974	Belongs to the 'phage' integrase family
AW02_RS04285	COG1484	DNA-dependent DNA replication
AW02_RS04395	COG1780	Probably involved in ribonucleotide reductase function
AW02_RS04400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW02_RS04410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW02_RS04415	COG0756	dUTP diphosphatase activity
AW02_RS04425	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AW02_RS04430	COG3584	3D domain protein
AW02_RS04430	COG1388	LysM domain
AW02_RS04480	COG1793	dna ligase
AW02_RS04530	COG0582	viral genome integration into host DNA
AW02_RS04625	COG1705	Flagellar rod assembly protein muramidase FlgJ
AW02_RS04635	COG5434	Belongs to the glycosyl hydrolase 28 family
AW02_RS04660	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW02_RS04660	COG3409	Peptidoglycan-binding domain 1 protein
AW02_RS04705	COG3340	Belongs to the peptidase S51 family
AW02_RS04715	COG0277	FAD linked oxidase domain protein
AW02_RS04725	COG0747	negative chemotaxis
AW02_RS04730	COG0601	transmembrane transport
AW02_RS04735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW02_RS04740	COG0444	Belongs to the ABC transporter superfamily
AW02_RS04745	COG4608	Belongs to the ABC transporter superfamily
AW02_RS04750	COG0753	catalase activity
AW02_RS04760	COG1116	anion transmembrane transporter activity
AW02_RS04765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW02_RS04770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW02_RS04790	COG1476	TRANSCRIPTIONal
AW02_RS04800	COG3382	B3 4 domain protein
AW02_RS04805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AW02_RS04815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AW02_RS04820	COG0789	Transcriptional regulator
AW02_RS04825	COG1664	Polymer-forming cytoskeletal
AW02_RS04830	COG1664	Polymer-forming cytoskeletal
AW02_RS04835	COG2766	serine protein kinase
AW02_RS04845	COG1846	Transcriptional regulator
AW02_RS04850	COG1566	PFAM secretion protein HlyD family protein
AW02_RS04855	COG2814	Major facilitator Superfamily
AW02_RS04860	COG0655	NAD(P)H dehydrogenase (quinone) activity
AW02_RS04875	COG1725	Transcriptional regulator
AW02_RS04880	COG1131	(ABC) transporter
AW02_RS04885	COG1131	(ABC) transporter
AW02_RS04890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW02_RS04895	COG1278	Cold shock
AW02_RS04900	COG1464	Belongs to the NlpA lipoprotein family
AW02_RS04905	COG3706	GGDEF domain
AW02_RS04910	COG1823	symporter activity
AW02_RS04930	COG5577	PFAM Coat F domain
AW02_RS04935	COG0737	Belongs to the 5'-nucleotidase family
AW02_RS04935	COG4085	toxin activity
AW02_RS04935	COG1525	nuclease
AW02_RS04940	COG3764	Sortase (surface protein transpeptidase)
AW02_RS04945	COG0564	pseudouridine synthase activity
AW02_RS04955	COG0517	IMP dehydrogenase activity
AW02_RS04960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW02_RS04965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW02_RS04965	COG3153	acetyltransferase
AW02_RS04970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW02_RS04975	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW02_RS04980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW02_RS04990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW02_RS04995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AW02_RS05000	COG2203	Gaf domain
AW02_RS05000	COG4585	Histidine kinase
AW02_RS05005	COG2197	response regulator
AW02_RS05010	COG0431	NADPH-dependent FMN reductase
AW02_RS05025	COG0791	NLP P60 protein
AW02_RS05025	COG1388	LysM domain
AW02_RS05030	COG1959	2 iron, 2 sulfur cluster binding
AW02_RS05035	COG0668	transmembrane transport
AW02_RS05040	COG2719	SpoVR family
AW02_RS05045	COG1785	Belongs to the alkaline phosphatase family
AW02_RS05050	COG0791	NLP P60 protein
AW02_RS05050	COG1388	LysM domain
AW02_RS05055	COG0583	DNA-binding transcription factor activity
AW02_RS05060	COG0372	Belongs to the citrate synthase family
AW02_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS05070	COG0531	amino acid
AW02_RS05075	COG0733	neurotransmitter:sodium symporter activity
AW02_RS05090	COG1595	DNA-templated transcription, initiation
AW02_RS05095	COG0204	Acyl-transferase
AW02_RS05100	COG1253	flavin adenine dinucleotide binding
AW02_RS05105	COG0789	Transcriptional regulator
AW02_RS05110	COG0436	Aminotransferase
AW02_RS05115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW02_RS05120	COG1253	flavin adenine dinucleotide binding
AW02_RS05125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW02_RS05130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW02_RS05135	COG0584	glycerophosphoryl diester phosphodiesterase
AW02_RS05140	COG0668	transmembrane transport
AW02_RS05145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AW02_RS05150	COG0726	polysaccharide deacetylase
AW02_RS05155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW02_RS05160	COG3226	Transcriptional regulator
AW02_RS05170	COG0589	response to stress
AW02_RS05175	COG1132	(ABC) transporter
AW02_RS05180	COG1132	(ABC) transporter
AW02_RS05185	COG0702	epimerase
AW02_RS05200	COG0189	ligase activity
AW02_RS05205	COG0189	ligase activity
AW02_RS05220	COG4335	DNA alkylation repair
AW02_RS05225	COG0561	phosphatase activity
AW02_RS05230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW02_RS05240	COG0475	glutathione-regulated potassium exporter activity
AW02_RS05245	COG0490	domain, Protein
AW02_RS05255	COG1024	Enoyl-CoA hydratase
AW02_RS05265	COG4152	abc transporter atp-binding protein
AW02_RS05270	COG1668	transmembrane transport
AW02_RS05275	COG0420	3'-5' exonuclease activity
AW02_RS05280	COG4717	serine-type aminopeptidase activity
AW02_RS05295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW02_RS05335	COG4980	gas vesicle protein
AW02_RS05350	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AW02_RS05355	COG0537	adenosine 5'-monophosphoramidase activity
AW02_RS05360	COG1131	(ABC) transporter
AW02_RS05365	COG4473	ABC transporter
AW02_RS05375	COG1473	amidohydrolase
AW02_RS05380	COG3069	C4-dicarboxylate transmembrane transporter activity
AW02_RS05385	COG2329	Antibiotic biosynthesis monooxygenase
AW02_RS05390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW02_RS05400	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AW02_RS05405	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AW02_RS05410	COG1309	transcriptional regulator
AW02_RS05415	COG1511	domain protein
AW02_RS05420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW02_RS05430	COG1363	Peptidase, m42
AW02_RS05435	COG1301	dicarboxylic acid transport
AW02_RS05440	COG1234	tRNA 3'-trailer cleavage
AW02_RS05445	COG0095	Lipoate-protein ligase
AW02_RS05450	COG0702	epimerase
AW02_RS05455	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS05465	COG0501	Belongs to the peptidase M48B family
AW02_RS05470	COG1404	Belongs to the peptidase S8 family
AW02_RS05480	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AW02_RS05485	COG0406	alpha-ribazole phosphatase activity
AW02_RS05490	COG0183	Belongs to the thiolase family
AW02_RS05495	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS05500	COG1268	BioY protein
AW02_RS05505	COG0840	transmembrane signaling receptor activity
AW02_RS05510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW02_RS05510	COG0723	plastoquinol--plastocyanin reductase activity
AW02_RS05515	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS05525	COG4903	ComK protein
AW02_RS05535	COG5646	InterPro IPR014922
AW02_RS05555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW02_RS05570	COG0398	Pfam SNARE associated Golgi protein
AW02_RS05575	COG0681	Belongs to the peptidase S26 family
AW02_RS05580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW02_RS05585	COG1846	Transcriptional regulator
AW02_RS05590	COG3180	Ammonia monooxygenase
AW02_RS05595	COG2814	Major facilitator Superfamily
AW02_RS05605	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AW02_RS05610	COG2323	membrane
AW02_RS05625	COG0420	3'-5' exonuclease activity
AW02_RS05630	COG0419	ATPase involved in DNA repair
AW02_RS05635	COG1403	HNH endonuclease
AW02_RS05675	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW02_RS05695	COG0367	asparagine synthase
AW02_RS05700	COG1562	ergosterol biosynthetic process
AW02_RS05705	COG0534	Mate efflux family protein
AW02_RS05710	COG2207	Transcriptional regulator
AW02_RS05710	COG1917	Cupin 2, conserved barrel domain protein
AW02_RS05715	COG1609	Transcriptional regulator
AW02_RS05720	COG0673	inositol 2-dehydrogenase activity
AW02_RS05725	COG2318	DinB family
AW02_RS05730	COG1357	PFAM Pentapeptide repeats (8 copies)
AW02_RS05735	COG2153	protein acetylation
AW02_RS05740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AW02_RS05740	COG0646	methionine synthase
AW02_RS05750	COG2996	Protein conserved in bacteria
AW02_RS05755	COG1744	ABC transporter substrate-binding protein PnrA-like
AW02_RS05760	COG0840	transmembrane signaling receptor activity
AW02_RS05765	COG1307	EDD domain protein, DegV family
AW02_RS05770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW02_RS05785	COG0561	phosphatase activity
AW02_RS05790	COG1073	alpha beta
AW02_RS05795	COG2151	metal-sulfur cluster biosynthetic enzyme
AW02_RS05810	COG0277	FAD linked oxidase domain protein
AW02_RS05815	COG2271	Major facilitator Superfamily
AW02_RS05825	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AW02_RS05835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW02_RS05840	COG0505	Belongs to the CarA family
AW02_RS05845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AW02_RS05850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AW02_RS05870	COG2267	carboxylic ester hydrolase activity
AW02_RS05880	COG1744	ABC transporter substrate-binding protein PnrA-like
AW02_RS05895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW02_RS05900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW02_RS05905	COG5504	Zn-dependent protease
AW02_RS05910	COG0444	Belongs to the ABC transporter superfamily
AW02_RS05915	COG4608	Belongs to the ABC transporter superfamily
AW02_RS05925	COG0601	transmembrane transport
AW02_RS05930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW02_RS05940	COG0180	Tryptophanyl-tRNA synthetase
AW02_RS05945	COG4166	transmembrane transport
AW02_RS05950	COG0601	transmembrane transport
AW02_RS05955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW02_RS05960	COG0444	Belongs to the ABC transporter superfamily
AW02_RS05965	COG4608	Belongs to the ABC transporter superfamily
AW02_RS05975	COG0456	acetyltransferase
AW02_RS05980	COG1393	Belongs to the ArsC family
AW02_RS05985	COG0861	Integral membrane protein TerC family
AW02_RS05990	COG4862	establishment of competence for transformation
AW02_RS05995	COG4469	Competence protein
AW02_RS06000	COG1164	Oligoendopeptidase f
AW02_RS06010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW02_RS06015	COG2346	COG2346, Truncated hemoglobins
AW02_RS06020	COG0741	lytic transglycosylase activity
AW02_RS06025	COG4116	CYTH
AW02_RS06035	COG2357	RelA SpoT domain protein
AW02_RS06040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AW02_RS06045	COG0564	pseudouridine synthase activity
AW02_RS06055	COG0475	glutathione-regulated potassium exporter activity
AW02_RS06055	COG0569	domain protein
AW02_RS06060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW02_RS06065	COG0352	thiamine-phosphate diphosphorylase activity
AW02_RS06070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW02_RS06075	COG2104	thiamine diphosphate biosynthetic process
AW02_RS06085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW02_RS06090	COG0351	phosphomethylpyrimidine kinase
AW02_RS06095	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AW02_RS06150	COG0210	DNA helicase
AW02_RS06170	COG1131	(ABC) transporter
AW02_RS06180	COG2153	protein acetylation
AW02_RS06190	COG2382	esterase
AW02_RS06195	COG0626	cystathionine gamma-synthase activity
AW02_RS06200	COG0626	cystathionine gamma-synthase activity
AW02_RS06220	COG4974	Belongs to the 'phage' integrase family
AW02_RS06325	COG5444	nuclease activity
AW02_RS06335	COG0346	lactoylglutathione lyase activity
AW02_RS06340	COG2367	Beta-lactamase
AW02_RS06345	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW02_RS06355	COG1846	Transcriptional regulator
AW02_RS06365	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AW02_RS06370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW02_RS06375	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AW02_RS06380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW02_RS06380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW02_RS06385	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW02_RS06395	COG1349	DNA-binding transcription factor activity
AW02_RS06410	COG1285	pathogenesis
AW02_RS06415	COG2205	protein histidine kinase activity
AW02_RS06425	COG3383	formate dehydrogenase (NAD+) activity
AW02_RS06430	COG2427	Protein of unknown function (DUF1641)
AW02_RS06435	COG2124	cytochrome p450
AW02_RS06440	COG1819	glycosyl
AW02_RS06450	COG1587	Uroporphyrinogen-III synthase
AW02_RS06455	COG0390	transport system, permease component
AW02_RS06460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW02_RS06465	COG0697	spore germination
AW02_RS06470	COG4297	protein containing double-stranded beta helix domain
AW02_RS06480	COG1252	NADH dehydrogenase
AW02_RS06490	COG2211	Major facilitator Superfamily
AW02_RS06495	COG1609	Transcriptional regulator
AW02_RS06500	COG0246	Mannitol dehydrogenase
AW02_RS06505	COG2721	sulfolactate sulfo-lyase activity
AW02_RS06510	COG0745	RESPONSE REGULATOR receiver
AW02_RS06515	COG2205	protein histidine kinase activity
AW02_RS06515	COG2770	Histidine kinase
AW02_RS06535	COG4585	Histidine kinase
AW02_RS06540	COG2197	response regulator
AW02_RS06565	COG0730	response to heat
AW02_RS06570	COG2318	DinB family
AW02_RS06575	COG0457	Tetratricopeptide repeat
AW02_RS06585	COG3409	Peptidoglycan-binding domain 1 protein
AW02_RS06585	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW02_RS06585	COG1388	LysM domain
AW02_RS06595	COG4195	phage-related replication protein
AW02_RS06600	COG2856	Zn peptidase
AW02_RS06605	COG1396	sequence-specific DNA binding
AW02_RS06615	COG1522	sequence-specific DNA binding
AW02_RS06620	COG1484	DNA-dependent DNA replication
AW02_RS06635	COG1595	DNA-templated transcription, initiation
AW02_RS06640	COG3728	DNA packaging
AW02_RS06640	COG5484	DNA packaging
AW02_RS06645	COG1783	phage Terminase large subunit
AW02_RS06650	COG5518	Phage portal protein
AW02_RS06655	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AW02_RS06660	COG4653	Phage capsid family
AW02_RS06705	COG3953	SLT domain
AW02_RS06705	COG5412	phage tail tape measure protein
AW02_RS06705	COG5412	phage tail tape measure protein
AW02_RS06705	COG5412	phage tail tape measure protein
AW02_RS06705	COG3953	SLT domain
AW02_RS06705	COG3953	SLT domain
AW02_RS06710	COG1652	LysM domain
AW02_RS06715	COG4193	domain, Protein
AW02_RS06725	COG3628	GPW Gp25 family protein
AW02_RS06730	COG3299	homolog of phage Mu protein gp47
AW02_RS06735	COG3778	Protein conserved in bacteria
AW02_RS06775	COG3409	Peptidoglycan-binding domain 1 protein
AW02_RS06775	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW02_RS06790	COG0306	phosphate transporter
AW02_RS06795	COG1392	Phosphate transport regulator
AW02_RS06800	COG0531	amino acid
AW02_RS06805	COG0346	lactoylglutathione lyase activity
AW02_RS06810	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AW02_RS06815	COG0463	Glycosyl transferase, family 2
AW02_RS06820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW02_RS06825	COG0477	Major facilitator Superfamily
AW02_RS06830	COG2362	D-Aminopeptidase
AW02_RS06835	COG0601	transmembrane transport
AW02_RS06840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW02_RS06845	COG0444	Belongs to the ABC transporter superfamily
AW02_RS06850	COG4166	transmembrane transport
AW02_RS06855	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW02_RS06860	COG4948	Mandelate Racemase Muconate Lactonizing
AW02_RS06865	COG0791	NLP P60 protein
AW02_RS06870	COG4608	Belongs to the ABC transporter superfamily
AW02_RS06875	COG2706	6-phosphogluconolactonase activity
AW02_RS06880	COG1834	amidinotransferase
AW02_RS06885	COG1607	acyl-coa hydrolase
AW02_RS06890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW02_RS06895	COG2076	Multidrug Resistance protein
AW02_RS06900	COG2076	Multidrug Resistance protein
AW02_RS06905	COG0788	formyltetrahydrofolate deformylase activity
AW02_RS06910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW02_RS06920	COG1764	response to oxidative stress
AW02_RS06925	COG1846	Transcriptional regulator
AW02_RS06930	COG1764	response to oxidative stress
AW02_RS06945	COG0463	Glycosyl transferase, family 2
AW02_RS06945	COG0457	Tetratricopeptide repeat
AW02_RS06955	COG2814	Major facilitator Superfamily
AW02_RS06960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW02_RS06970	COG1404	Belongs to the peptidase S8 family
AW02_RS06975	COG1366	Belongs to the anti-sigma-factor antagonist family
AW02_RS06980	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW02_RS06985	COG1122	ATPase activity
AW02_RS06990	COG4721	ABC-type cobalt transport system, permease component
AW02_RS06995	COG3858	chitin binding
AW02_RS06995	COG1388	LysM domain
AW02_RS07000	COG2239	Acts as a magnesium transporter
AW02_RS07005	COG0789	Transcriptional regulator
AW02_RS07015	COG1846	Transcriptional regulator
AW02_RS07020	COG0726	polysaccharide deacetylase
AW02_RS07025	COG3285	dna ligase
AW02_RS07025	COG1793	dna ligase
AW02_RS07030	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AW02_RS07040	COG0586	Pfam SNARE associated Golgi protein
AW02_RS07045	COG0861	Integral membrane protein TerC family
AW02_RS07050	COG1191	sigma factor activity
AW02_RS07075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW02_RS07080	COG2323	membrane
AW02_RS07085	COG3594	Acyltransferase
AW02_RS07090	COG5002	protein histidine kinase activity
AW02_RS07095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW02_RS07110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW02_RS07115	COG0436	Aminotransferase
AW02_RS07145	COG3852	Histidine kinase
AW02_RS07150	COG1846	Transcriptional regulator
AW02_RS07155	COG1360	Flagellar Motor Protein
AW02_RS07160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW02_RS07165	COG0542	response to heat
AW02_RS07170	COG3949	Membrane
AW02_RS07185	COG0720	synthase
AW02_RS07190	COG0602	queuosine metabolic process
AW02_RS07205	COG4873	Protein conserved in bacteria
AW02_RS07215	COG3773	Cell wall hydrolase
AW02_RS07220	COG2244	polysaccharide biosynthetic process
AW02_RS07225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW02_RS07230	COG2217	Heavy metal translocating P-type atpase
AW02_RS07235	COG0006	proline dipeptidase activity
AW02_RS07240	COG1609	Transcriptional regulator
AW02_RS07245	COG3711	transcriptional antiterminator
AW02_RS07250	COG1263	PTS System
AW02_RS07250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW02_RS07250	COG2190	(PTS) system
AW02_RS07255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW02_RS07260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AW02_RS07270	COG1533	DNA photolyase activity
AW02_RS07275	COG0840	transmembrane signaling receptor activity
AW02_RS07280	COG2084	Dehydrogenase
AW02_RS07285	COG2340	Cysteine-rich secretory protein family
AW02_RS07290	COG0768	penicillin binding
AW02_RS07295	COG4191	Histidine kinase
AW02_RS07300	COG0436	Aminotransferase
AW02_RS07305	COG0835	chemotaxis
AW02_RS07305	COG0784	Response regulator, receiver
AW02_RS07315	COG2814	Major facilitator Superfamily
AW02_RS07320	COG1376	ErfK ybiS ycfS ynhG family protein
AW02_RS07325	COG1408	metallophosphoesterase
AW02_RS07330	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS07340	COG2200	EAL domain
AW02_RS07345	COG4703	Protein of unknown function (DUF1797)
AW02_RS07350	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AW02_RS07360	COG0517	IMP dehydrogenase activity
AW02_RS07365	COG0583	DNA-binding transcription factor activity
AW02_RS07370	COG0716	FMN binding
AW02_RS07380	COG0716	FMN binding
AW02_RS07400	COG0668	transmembrane transport
AW02_RS07405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW02_RS07425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW02_RS07430	COG0303	'Molybdopterin
AW02_RS07435	COG1763	Mo-molybdopterin cofactor biosynthetic process
AW02_RS07440	COG0314	molybdopterin synthase activity
AW02_RS07445	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AW02_RS07455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW02_RS07460	COG1136	(ABC) transporter
AW02_RS07465	COG0577	efflux transmembrane transporter activity
AW02_RS07470	COG1349	DNA-binding transcription factor activity
AW02_RS07475	COG1105	Belongs to the carbohydrate kinase PfkB family
AW02_RS07480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW02_RS07480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW02_RS07480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW02_RS07485	COG0681	Belongs to the peptidase S26 family
AW02_RS07495	COG0488	(ABC) transporter
AW02_RS07500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW02_RS07505	COG2309	aminopeptidase activity
AW02_RS07510	COG1077	Cell shape determining protein MreB Mrl
AW02_RS07520	COG2002	toxin-antitoxin pair type II binding
AW02_RS07525	COG3852	Histidine kinase
AW02_RS07530	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AW02_RS07530	COG2105	PFAM AIG2 family protein
AW02_RS07535	COG0569	domain protein
AW02_RS07545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW02_RS07555	COG0561	phosphatase activity
AW02_RS07560	COG0242	peptide deformylase activity
AW02_RS07570	COG0497	DNA recombination
AW02_RS07580	COG4221	oxidoreductase activity
AW02_RS07580	COG3321	synthase
AW02_RS07580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS07580	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS07585	COG0300	oxidoreductase activity
AW02_RS07585	COG3321	synthase
AW02_RS07585	COG4221	oxidoreductase activity
AW02_RS07585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS07590	COG4221	oxidoreductase activity
AW02_RS07590	COG3321	synthase
AW02_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS07590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS07595	COG4221	oxidoreductase activity
AW02_RS07595	COG3321	synthase
AW02_RS07595	COG0300	oxidoreductase activity
AW02_RS07595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS07600	COG4221	oxidoreductase activity
AW02_RS07600	COG3321	synthase
AW02_RS07600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS07600	COG0300	oxidoreductase activity
AW02_RS07605	COG0300	oxidoreductase activity
AW02_RS07605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS07605	COG4221	oxidoreductase activity
AW02_RS07605	COG3321	synthase
AW02_RS07610	COG3321	synthase
AW02_RS07610	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS07610	COG4221	oxidoreductase activity
AW02_RS07610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS07615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW02_RS07620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW02_RS07625	COG0022	dehydrogenase e1 component
AW02_RS07630	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW02_RS07635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW02_RS07640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW02_RS07650	COG1982	Orn Lys Arg decarboxylase major
AW02_RS07670	COG0483	inositol monophosphate 1-phosphatase activity
AW02_RS07680	COG3227	Zinc metalloprotease (Elastase)
AW02_RS07695	COG1595	DNA-templated transcription, initiation
AW02_RS07715	COG1217	gtp-binding protein TYPA
AW02_RS07725	COG4896	Protein conserved in bacteria
AW02_RS07735	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AW02_RS07740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW02_RS07745	COG2066	Belongs to the glutaminase family
AW02_RS07755	COG0772	Belongs to the SEDS family
AW02_RS07760	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AW02_RS07775	COG2010	Cytochrome c
AW02_RS07775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW02_RS07780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW02_RS07785	COG1845	cytochrome c oxidase, subunit III
AW02_RS07790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AW02_RS07795	COG3336	cytochrome c oxidase
AW02_RS07805	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AW02_RS07810	COG2340	Cysteine-rich secretory protein family
AW02_RS07825	COG3679	Belongs to the UPF0342 family
AW02_RS07840	COG0742	ribosomal rna small subunit methyltransferase
AW02_RS07850	COG3314	Sporulation integral membrane protein YlbJ
AW02_RS07855	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW02_RS07860	COG3480	Lon protease (S16) C-terminal proteolytic domain
AW02_RS07870	COG1399	metal-binding, possibly nucleic acid-binding protein
AW02_RS07885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW02_RS07905	COG4839	cell division protein FtsL
AW02_RS07910	COG0768	penicillin binding
AW02_RS07915	COG0768	penicillin binding
AW02_RS07935	COG0772	Belongs to the SEDS family
AW02_RS07950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AW02_RS07955	COG0849	cell division
AW02_RS07960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AW02_RS07965	COG4412	M6 family metalloprotease domain protein
AW02_RS07965	COG1404	Belongs to the peptidase S8 family
AW02_RS07975	COG1191	sigma factor activity
AW02_RS07980	COG1191	sigma factor activity
AW02_RS07985	COG1119	ATPase activity
AW02_RS07990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW02_RS07995	COG1873	PFAM PRC-barrel domain
AW02_RS08000	COG1496	oxidoreductase activity
AW02_RS08005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AW02_RS08015	COG0762	integral membrane protein
AW02_RS08020	COG2302	S4 RNA-binding domain
AW02_RS08025	COG3599	regulation of cell shape
AW02_RS08035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AW02_RS08040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW02_RS08050	COG0564	pseudouridine synthase activity
AW02_RS08060	COG2233	PERMEase
AW02_RS08070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AW02_RS08075	COG0505	Belongs to the CarA family
AW02_RS08080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AW02_RS08095	COG0284	orotidine-5'-phosphate decarboxylase activity
AW02_RS08100	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AW02_RS08110	COG0306	phosphate transporter
AW02_RS08125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW02_RS08130	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AW02_RS08135	COG1648	precorrin-2 dehydrogenase activity
AW02_RS08145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW02_RS08150	COG1561	YicC-like family, N-terminal region
AW02_RS08160	COG0194	GDP metabolic process
AW02_RS08170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW02_RS08175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW02_RS08180	COG0242	peptide deformylase activity
AW02_RS08190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW02_RS08190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AW02_RS08200	COG0631	protein serine/threonine phosphatase activity
AW02_RS08205	COG0515	serine threonine protein kinase
AW02_RS08205	COG2815	serine threonine protein kinase
AW02_RS08215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW02_RS08220	COG1564	THIamine pyrophosphokinase
AW02_RS08235	COG1302	Protein conserved in bacteria
AW02_RS08240	COG1461	Dihydroxyacetone kinase
AW02_RS08245	COG1760	l-serine dehydratase
AW02_RS08250	COG1760	l-serine dehydratase
AW02_RS08255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AW02_RS08270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW02_RS08275	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS08290	COG1196	nuclear chromosome segregation
AW02_RS08295	COG0552	protein localization to endoplasmic reticulum
AW02_RS08310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AW02_RS08320	COG1837	Belongs to the UPF0109 family
AW02_RS08345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW02_RS08360	COG2257	FlhB HrpN YscU SpaS Family
AW02_RS08370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW02_RS08375	COG0758	DNA mediated transformation
AW02_RS08380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW02_RS08390	COG4974	Belongs to the 'phage' integrase family
AW02_RS08410	COG1815	bacterial-type flagellum-dependent cell motility
AW02_RS08415	COG1558	bacterial-type flagellum-dependent cell motility
AW02_RS08420	COG1677	Flagellar hook-basal body complex protein FliE
AW02_RS08425	COG1766	The M ring may be actively involved in energy transduction
AW02_RS08430	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW02_RS08435	COG1317	bacterial-type flagellum organization
AW02_RS08440	COG1157	protein secretion by the type III secretion system
AW02_RS08445	COG2882	bacterial-type flagellum organization
AW02_RS08450	COG3334	PFAM MgtE intracellular
AW02_RS08455	COG3144	bacterial-type flagellum assembly
AW02_RS08460	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AW02_RS08465	COG4786	Flagellar basal body rod
AW02_RS08470	COG1582	Flagellar protein (FlbD)
AW02_RS08475	COG1580	Controls the rotational direction of flagella during chemotaxis
AW02_RS08480	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW02_RS08485	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW02_RS08485	COG1776	CheC inhibitor of MCP methylation
AW02_RS08490	COG2201	protein-glutamate methylesterase activity
AW02_RS08495	COG3190	flagellar
AW02_RS08500	COG1338	Plays a role in the flagellum-specific transport system
AW02_RS08505	COG1987	bacterial-type flagellum assembly
AW02_RS08510	COG1684	flagellar biosynthetic protein fliR
AW02_RS08515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW02_RS08520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW02_RS08525	COG1419	protein localization to endoplasmic reticulum
AW02_RS08530	COG0455	bacterial-type flagellum organization
AW02_RS08535	COG2201	protein-glutamate methylesterase activity
AW02_RS08540	COG2198	Histidine kinase
AW02_RS08540	COG0643	Histidine kinase
AW02_RS08545	COG0835	chemotaxis
AW02_RS08550	COG1776	CheC inhibitor of MCP methylation
AW02_RS08560	COG1191	sigma factor activity
AW02_RS08590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AW02_RS08595	COG4589	Belongs to the CDS family
AW02_RS08605	COG0750	zinc metalloprotease
AW02_RS08615	COG2176	DNA-directed DNA polymerase activity
AW02_RS08625	COG0195	Participates in both transcription termination and antitermination
AW02_RS08630	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AW02_RS08635	COG1358	cellular component organization or biogenesis
AW02_RS08645	COG1550	Protein conserved in bacteria
AW02_RS08660	COG0196	riboflavin kinase activity
AW02_RS08675	COG0726	polysaccharide deacetylase
AW02_RS08680	COG0612	Peptidase, M16
AW02_RS08685	COG1873	PFAM PRC-barrel domain
AW02_RS08690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW02_RS08695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW02_RS08700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW02_RS08705	COG0527	aspartate kinase activity
AW02_RS08715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW02_RS08720	COG0740	serine-type endopeptidase activity
AW02_RS08730	COG4980	gas vesicle protein
AW02_RS08730	COG1674	ftsk spoiiie
AW02_RS08735	COG2188	Transcriptional regulator
AW02_RS08740	COG2814	Major facilitator Superfamily
AW02_RS08745	COG1846	Transcriptional regulator
AW02_RS08750	COG2409	Drug exporters of the RND superfamily
AW02_RS08750	COG1033	growth of symbiont in host cell
AW02_RS08755	COG0612	Peptidase, M16
AW02_RS08760	COG0612	Peptidase, M16
AW02_RS08765	COG0300	oxidoreductase activity
AW02_RS08780	COG1426	Protein conserved in bacteria
AW02_RS08785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AW02_RS08800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW02_RS08810	COG1692	metallophosphoesterase
AW02_RS08815	COG2359	stage V sporulation protein S
AW02_RS08835	COG4550	Control of competence regulator ComK, YlbF/YmcA
AW02_RS08895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS08900	COG3425	synthase
AW02_RS08905	COG1024	Enoyl-CoA hydratase
AW02_RS08910	COG1024	Enoyl-CoA hydratase
AW02_RS08915	COG3321	synthase
AW02_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS08915	COG0300	oxidoreductase activity
AW02_RS08915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS08915	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS08920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS08920	COG3321	synthase
AW02_RS08920	COG0300	oxidoreductase activity
AW02_RS08920	COG4221	oxidoreductase activity
AW02_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS08925	COG3321	synthase
AW02_RS08925	COG3321	synthase
AW02_RS08925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS08925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW02_RS08925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS08925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS08925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW02_RS08925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS08930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS08930	COG4221	oxidoreductase activity
AW02_RS08930	COG3321	synthase
AW02_RS08935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS08935	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AW02_RS08935	COG3321	synthase
AW02_RS08935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW02_RS08940	COG2124	cytochrome p450
AW02_RS08945	COG3209	COG3209 Rhs family protein
AW02_RS08950	COG3619	membrane
AW02_RS08960	COG1404	Belongs to the peptidase S8 family
AW02_RS08970	COG4195	phage-related replication protein
AW02_RS08975	COG1764	response to oxidative stress
AW02_RS08985	COG2076	Multidrug Resistance protein
AW02_RS09025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW02_RS09030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW02_RS09035	COG4112	unkown
AW02_RS09040	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW02_RS09050	COG0464	growth
AW02_RS09055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW02_RS09060	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AW02_RS09065	COG0789	Transcriptional regulator
AW02_RS09070	COG0174	glutamine synthetase
AW02_RS09080	COG2211	Major facilitator Superfamily
AW02_RS09085	COG3507	Belongs to the glycosyl hydrolase 43 family
AW02_RS09100	COG1070	Carbohydrate kinase
AW02_RS09105	COG0574	Belongs to the PEP-utilizing enzyme family
AW02_RS09105	COG3848	Pyruvate phosphate dikinase
AW02_RS09120	COG1064	alcohol dehydrogenase
AW02_RS09160	COG3397	chitin binding
AW02_RS09175	COG5434	Belongs to the glycosyl hydrolase 28 family
AW02_RS09185	COG0756	dUTP diphosphatase activity
AW02_RS09190	COG4195	phage-related replication protein
AW02_RS09225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW02_RS09235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AW02_RS09255	COG0785	Cytochrome C biogenesis protein
AW02_RS09260	COG2201	protein-glutamate methylesterase activity
AW02_RS09265	COG4846	Membrane protein involved in cytochrome C biogenesis
AW02_RS09275	COG0071	Belongs to the small heat shock protein (HSP20) family
AW02_RS09290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AW02_RS09295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW02_RS09310	COG0824	Thioesterase
AW02_RS09320	COG4841	protein insertion into membrane
AW02_RS09330	COG1832	CoA-binding protein
AW02_RS09335	COG0187	DNA topoisomerase II activity
AW02_RS09340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW02_RS09350	COG1115	amino acid carrier protein
AW02_RS09360	COG1063	alcohol dehydrogenase
AW02_RS09365	COG0800	Aldolase
AW02_RS09370	COG1312	Catalyzes the dehydration of D-mannonate
AW02_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS09380	COG1609	Transcriptional regulator
AW02_RS09385	COG2271	Major facilitator Superfamily
AW02_RS09385	COG2271	Major facilitator Superfamily
AW02_RS09420	COG2205	protein histidine kinase activity
AW02_RS09425	COG0745	RESPONSE REGULATOR receiver
AW02_RS09435	COG3507	Belongs to the glycosyl hydrolase 43 family
AW02_RS09460	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS09465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW02_RS09470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW02_RS09475	COG2610	gluconate transmembrane transporter activity
AW02_RS09480	COG2124	cytochrome p450
AW02_RS09500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW02_RS09510	COG2246	polysaccharide biosynthetic process
AW02_RS09515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW02_RS09520	COG0586	Pfam SNARE associated Golgi protein
AW02_RS09525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW02_RS09530	COG1024	Enoyl-CoA hydratase
AW02_RS09535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW02_RS09540	COG0511	ligase activity, forming carbon-carbon bonds
AW02_RS09545	COG0439	Biotin carboxylase
AW02_RS09550	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS09555	COG1960	acyl-CoA dehydrogenase activity
AW02_RS09560	COG1649	PFAM Uncharacterised BCR, COG1649
AW02_RS09570	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AW02_RS09570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS09575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS09580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS09585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS09590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS09600	COG2027	D-alanyl-D-alanine carboxypeptidase
AW02_RS09605	COG2017	converts alpha-aldose to the beta-anomer
AW02_RS09610	COG0534	Mate efflux family protein
AW02_RS09620	COG5444	nuclease activity
AW02_RS09635	COG3409	Peptidoglycan-binding domain 1 protein
AW02_RS09635	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW02_RS09665	COG5434	Belongs to the glycosyl hydrolase 28 family
AW02_RS09670	COG1388	LysM domain
AW02_RS09670	COG1705	Flagellar rod assembly protein muramidase FlgJ
AW02_RS09745	COG4626	Terminase
AW02_RS09745	COG1802	Transcriptional regulator
AW02_RS09780	COG0582	viral genome integration into host DNA
AW02_RS09785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AW02_RS09870	COG0582	viral genome integration into host DNA
AW02_RS09875	COG0166	Belongs to the GPI family
AW02_RS09880	COG0405	Gamma-glutamyltransferase
AW02_RS09885	COG2814	Major facilitator Superfamily
AW02_RS09890	COG0640	Transcriptional regulator
AW02_RS09905	COG0604	alcohol dehydrogenase
AW02_RS09910	COG0493	'glutamate synthase
AW02_RS09915	COG0070	glutamate synthase
AW02_RS09915	COG0069	glutamate synthase activity
AW02_RS09915	COG0067	glutamate synthase
AW02_RS09920	COG0583	DNA-binding transcription factor activity
AW02_RS09925	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW02_RS09940	COG0300	oxidoreductase activity
AW02_RS09945	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AW02_RS09955	COG2814	Major facilitator Superfamily
AW02_RS09960	COG1070	Carbohydrate kinase
AW02_RS09965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW02_RS09970	COG0243	molybdopterin cofactor binding
AW02_RS09990	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS09995	COG1733	regulation of RNA biosynthetic process
AW02_RS10000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW02_RS10005	COG2207	Transcriptional regulator
AW02_RS10005	COG0662	Cupin 2, conserved barrel domain protein
AW02_RS10010	COG1309	transcriptional regulator
AW02_RS10015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW02_RS10025	COG0640	Transcriptional regulator
AW02_RS10030	COG0741	lytic transglycosylase activity
AW02_RS10035	COG2322	membrane
AW02_RS10050	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW02_RS10060	COG3584	3D domain protein
AW02_RS10060	COG1388	LysM domain
AW02_RS10065	COG0514	ATP-dependent DNA helicase (RecQ)
AW02_RS10070	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW02_RS10075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW02_RS10090	COG0071	Belongs to the small heat shock protein (HSP20) family
AW02_RS10115	COG1012	belongs to the aldehyde dehydrogenase family
AW02_RS10120	COG1657	PFAM Prenyltransferase squalene oxidase
AW02_RS10125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW02_RS10130	COG0733	neurotransmitter:sodium symporter activity
AW02_RS10135	COG0385	Bile acid
AW02_RS10140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW02_RS10145	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW02_RS10155	COG4548	von Willebrand factor, type A
AW02_RS10160	COG0714	Associated with various cellular activities
AW02_RS10165	COG2032	superoxide dismutase activity
AW02_RS10170	COG1388	LysM domain
AW02_RS10170	COG0791	NLP P60 protein
AW02_RS10175	COG1819	glycosyl
AW02_RS10180	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW02_RS10185	COG0534	Mate efflux family protein
AW02_RS10190	COG1366	Belongs to the anti-sigma-factor antagonist family
AW02_RS10195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW02_RS10200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW02_RS10210	COG2962	Rard protein
AW02_RS10225	COG1942	4-Oxalocrotonate Tautomerase
AW02_RS10235	COG1733	regulation of RNA biosynthetic process
AW02_RS10240	COG0778	Nitroreductase
AW02_RS10245	COG0400	carboxylic ester hydrolase activity
AW02_RS10250	COG0346	lactoylglutathione lyase activity
AW02_RS10260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW02_RS10270	COG2723	6-phospho-beta-galactosidase activity
AW02_RS10275	COG2188	Transcriptional regulator
AW02_RS10280	COG3409	Peptidoglycan-binding domain 1 protein
AW02_RS10280	COG0793	Belongs to the peptidase S41A family
AW02_RS10285	COG2226	methyltransferase
AW02_RS10295	COG1876	peptidase activity
AW02_RS10310	COG0671	phosphoesterase, PA-phosphatase related
AW02_RS10340	COG1509	lysine 2,3-aminomutase activity
AW02_RS10345	COG0456	acetyltransferase
AW02_RS10350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW02_RS10355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW02_RS10360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW02_RS10365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW02_RS10370	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AW02_RS10380	COG0456	acetyltransferase
AW02_RS10385	COG0463	Glycosyl transferase, family 2
AW02_RS10400	COG4641	Protein conserved in bacteria
AW02_RS10410	COG1086	Polysaccharide biosynthesis protein
AW02_RS10455	COG1388	LysM domain
AW02_RS10460	COG0457	Tetratricopeptide repeat
AW02_RS10505	COG5444	nuclease activity
AW02_RS10510	COG4282	regulation of fungal-type cell wall biogenesis
AW02_RS10520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW02_RS10540	COG1846	Transcriptional regulator
AW02_RS10545	COG4698	Protein conserved in bacteria
AW02_RS10550	COG2755	lipolytic protein G-D-S-L family
AW02_RS10555	COG1999	signal sequence binding
AW02_RS10565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AW02_RS10570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW02_RS10575	COG1272	protein, Hemolysin III
AW02_RS10580	COG0204	Acyl-transferase
AW02_RS10585	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW02_RS10600	COG2136	Putative SAM-dependent methyltransferase
AW02_RS10600	COG2521	methyltransferase
AW02_RS10615	COG1413	lyase activity
AW02_RS10620	COG1418	mRNA catabolic process
AW02_RS10625	COG0386	Belongs to the glutathione peroxidase family
AW02_RS10635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW02_RS10640	COG1278	Cold shock
AW02_RS10660	COG0328	RNA-DNA hybrid ribonuclease activity
AW02_RS10665	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AW02_RS10670	COG0328	RNA-DNA hybrid ribonuclease activity
AW02_RS10680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW02_RS10690	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW02_RS10695	COG1755	Isoprenylcysteine carboxyl methyltransferase
AW02_RS10700	COG3424	synthase
AW02_RS10725	COG1335	isochorismatase
AW02_RS10750	COG0438	transferase activity, transferring glycosyl groups
AW02_RS10755	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW02_RS10760	COG4824	toxin secretion phage lysis holin
AW02_RS10780	COG5434	Belongs to the glycosyl hydrolase 28 family
AW02_RS10785	COG1705	Flagellar rod assembly protein muramidase FlgJ
AW02_RS10795	COG3953	SLT domain
AW02_RS10795	COG5280	Phage tail tape measure protein TP901
AW02_RS10890	COG1595	DNA-templated transcription, initiation
AW02_RS10925	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AW02_RS10930	COG1484	DNA-dependent DNA replication
AW02_RS10935	COG3935	DnaD domain protein
AW02_RS10975	COG3645	SOS response
AW02_RS10975	COG3646	Phage regulatory protein
AW02_RS10985	COG3620	sequence-specific DNA binding
AW02_RS10990	COG0582	viral genome integration into host DNA
AW02_RS10995	COG2233	PERMEase
AW02_RS11005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AW02_RS11010	COG1199	ATP-dependent helicase activity
AW02_RS11020	COG0116	Belongs to the methyltransferase superfamily
AW02_RS11035	COG3359	exonuclease
AW02_RS11040	COG1111	helicase
AW02_RS11040	COG1205	dead DEAH box helicase
AW02_RS11045	COG2190	(PTS) system
AW02_RS11050	COG0071	Belongs to the small heat shock protein (HSP20) family
AW02_RS11090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW02_RS11090	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW02_RS11100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AW02_RS11105	COG3935	DnaD domain protein
AW02_RS11115	COG0436	Aminotransferase
AW02_RS11120	COG5353	protein conserved in bacteria
AW02_RS11125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW02_RS11125	COG1199	ATP-dependent helicase activity
AW02_RS11155	COG0438	transferase activity, transferring glycosyl groups
AW02_RS11160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW02_RS11175	COG1694	Mazg nucleotide pyrophosphohydrolase
AW02_RS11180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW02_RS11185	COG2140	Oxalate decarboxylase
AW02_RS11195	COG4347	Protein of unknown function (DUF1405)
AW02_RS11200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW02_RS11200	COG2010	Cytochrome c
AW02_RS11205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW02_RS11210	COG0723	plastoquinol--plastocyanin reductase activity
AW02_RS11225	COG0457	Tetratricopeptide repeat
AW02_RS11235	COG0287	Prephenate dehydrogenase
AW02_RS11270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW02_RS11275	COG4401	Chorismate mutase type I
AW02_RS11290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW02_RS11295	COG0105	UTP biosynthetic process
AW02_RS11300	COG0142	geranyltranstransferase activity
AW02_RS11310	COG0142	geranyltranstransferase activity
AW02_RS11325	COG0776	regulation of translation
AW02_RS11330	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW02_RS11365	COG0539	negative regulation of cytoplasmic translation
AW02_RS11375	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AW02_RS11380	COG2959	enzyme of heme biosynthesis
AW02_RS11385	COG3409	Peptidoglycan-binding domain 1 protein
AW02_RS11385	COG3773	Cell wall hydrolase
AW02_RS11390	COG2339	peptidase activity
AW02_RS11395	COG0492	ferredoxin-NADP+ reductase activity
AW02_RS11400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW02_RS11405	COG4862	establishment of competence for transformation
AW02_RS11410	COG1408	metallophosphoesterase
AW02_RS11420	COG1388	LysM domain
AW02_RS11425	COG1266	CAAX protease self-immunity
AW02_RS11430	COG0514	ATP-dependent DNA helicase (RecQ)
AW02_RS11435	COG4955	Helix-turn-helix domain
AW02_RS11440	COG1141	Ferredoxin
AW02_RS11445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AW02_RS11450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW02_RS11460	COG1595	DNA-templated transcription, initiation
AW02_RS11465	COG5002	protein histidine kinase activity
AW02_RS11470	COG0745	RESPONSE REGULATOR receiver
AW02_RS11475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW02_RS11480	COG1333	cytochrome c biogenesis protein
AW02_RS11485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW02_RS11490	COG1187	pseudouridine synthase activity
AW02_RS11495	COG0700	Nucleoside recognition
AW02_RS11500	COG2715	membrane protein required for spore maturation
AW02_RS11505	COG1686	Belongs to the peptidase S11 family
AW02_RS11525	COG1547	Domain of unknown function (DUF309)
AW02_RS11530	COG0456	acetyltransferase
AW02_RS11545	COG0307	riboflavin synthase, alpha
AW02_RS11550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW02_RS11550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW02_RS11560	COG0681	Belongs to the peptidase S26 family
AW02_RS11570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW02_RS11575	COG4086	secreted protein
AW02_RS11580	COG0019	diaminopimelate decarboxylase activity
AW02_RS11585	COG0697	spore germination
AW02_RS11600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW02_RS11620	COG1191	sigma factor activity
AW02_RS11630	COG1366	Belongs to the anti-sigma-factor antagonist family
AW02_RS11635	COG1686	Belongs to the peptidase S11 family
AW02_RS11640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AW02_RS11645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AW02_RS11650	COG4974	Belongs to the 'phage' integrase family
AW02_RS11660	COG0735	belongs to the Fur family
AW02_RS11665	COG1300	Membrane
AW02_RS11680	COG0281	malic enzyme
AW02_RS11685	COG1757	Na H antiporter
AW02_RS11690	COG1027	Aspartate ammonia-lyase
AW02_RS11695	COG0252	asparaginase activity
AW02_RS11700	COG1396	sequence-specific DNA binding
AW02_RS11705	COG1379	DNA repair
AW02_RS11710	COG0494	nUDIX hydrolase
AW02_RS11720	COG0667	Aldo Keto reductase
AW02_RS11730	COG1073	alpha beta
AW02_RS11740	COG4918	Iron-sulphur cluster biosynthesis
AW02_RS11745	COG0456	acetyltransferase
AW02_RS11745	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW02_RS11750	COG2329	Antibiotic biosynthesis monooxygenase
AW02_RS11755	COG0456	acetyltransferase
AW02_RS11760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW02_RS11775	COG0628	permease
AW02_RS11780	COG0346	lactoylglutathione lyase activity
AW02_RS11790	COG3048	D-serine ammonia-lyase activity
AW02_RS11795	COG0300	oxidoreductase activity
AW02_RS11800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW02_RS11805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW02_RS11810	COG1024	Enoyl-CoA hydratase
AW02_RS11815	COG3425	synthase
AW02_RS11820	COG2124	cytochrome p450
AW02_RS11825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW02_RS11825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS11825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS11825	COG3321	synthase
AW02_RS11830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS11830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS11830	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS11830	COG3321	synthase
AW02_RS11830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW02_RS11835	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS11835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS11835	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS11835	COG3321	synthase
AW02_RS11835	COG0300	oxidoreductase activity
AW02_RS11840	COG0300	oxidoreductase activity
AW02_RS11840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS11840	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS11840	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS11840	COG3321	synthase
AW02_RS11845	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS11845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS11845	COG3321	synthase
AW02_RS11845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW02_RS11845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS11850	COG3321	synthase
AW02_RS11850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS11850	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS11850	COG0300	oxidoreductase activity
AW02_RS11850	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS11855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS11855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW02_RS11855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW02_RS11855	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS11855	COG3321	synthase
AW02_RS11860	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS11865	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS11880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW02_RS11880	COG2070	2-Nitropropane dioxygenase
AW02_RS11885	COG0250	Participates in transcription elongation, termination and antitermination
AW02_RS11905	COG0596	Alpha beta hydrolase
AW02_RS11915	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW02_RS11920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW02_RS11935	COG0706	membrane insertase activity
AW02_RS11940	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW02_RS11945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW02_RS11950	COG0346	lactoylglutathione lyase activity
AW02_RS11955	COG1376	ErfK ybiS ycfS ynhG family protein
AW02_RS11960	COG4129	membrane
AW02_RS11965	COG1126	abc transporter atp-binding protein
AW02_RS11970	COG0765	amino acid transport
AW02_RS11975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW02_RS11985	COG1597	lipid kinase activity
AW02_RS11990	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW02_RS11995	COG0022	dehydrogenase e1 component
AW02_RS12000	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW02_RS12005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW02_RS12010	COG3426	butyrate kinase activity
AW02_RS12015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW02_RS12020	COG0280	phosphate acetyltransferase
AW02_RS12025	COG3829	transcription factor binding
AW02_RS12025	COG3290	protein histidine kinase activity
AW02_RS12035	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AW02_RS12040	COG2079	MmgE PrpD family protein
AW02_RS12045	COG0372	Belongs to the citrate synthase family
AW02_RS12050	COG1960	acyl-CoA dehydrogenase activity
AW02_RS12055	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW02_RS12060	COG0183	Belongs to the thiolase family
AW02_RS12065	COG0584	glycerophosphoryl diester phosphodiesterase
AW02_RS12070	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW02_RS12095	COG1902	pentaerythritol trinitrate reductase activity
AW02_RS12110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW02_RS12115	COG0745	RESPONSE REGULATOR receiver
AW02_RS12120	COG0750	zinc metalloprotease
AW02_RS12125	COG0497	DNA recombination
AW02_RS12135	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AW02_RS12145	COG0142	geranyltranstransferase activity
AW02_RS12155	COG1570	exodeoxyribonuclease VII activity
AW02_RS12170	COG1302	Protein conserved in bacteria
AW02_RS12175	COG0439	Biotin carboxylase
AW02_RS12180	COG0511	ligase activity, forming carbon-carbon bonds
AW02_RS12220	COG3854	ATPases associated with a variety of cellular activities
AW02_RS12235	COG0006	proline dipeptidase activity
AW02_RS12245	COG3872	metal-dependent enzyme
AW02_RS12255	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW02_RS12270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW02_RS12290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW02_RS12305	COG1396	sequence-specific DNA binding
AW02_RS12315	COG0681	Belongs to the peptidase S26 family
AW02_RS12340	COG4940	Competence protein ComGF
AW02_RS12350	COG4970	Tfp pilus assembly protein FimT
AW02_RS12355	COG4537	Required for transformation and DNA binding
AW02_RS12360	COG1459	type II secretion system
AW02_RS12365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW02_RS12370	COG0598	Magnesium transport protein CorA
AW02_RS12375	COG1253	flavin adenine dinucleotide binding
AW02_RS12380	COG1366	Belongs to the anti-sigma-factor antagonist family
AW02_RS12390	COG1393	Belongs to the ArsC family
AW02_RS12400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW02_RS12410	COG0011	TIGRFAM Protein of
AW02_RS12420	COG2866	Carboxypeptidase
AW02_RS12425	COG1940	carbohydrate kinase activity
AW02_RS12430	COG4483	Protein conserved in bacteria
AW02_RS12435	COG1757	Na H antiporter
AW02_RS12440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AW02_RS12450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW02_RS12455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW02_RS12460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW02_RS12465	COG0581	inorganic phosphate transmembrane transporter activity
AW02_RS12470	COG0573	inorganic phosphate transmembrane transporter activity
AW02_RS12475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW02_RS12480	COG0768	penicillin binding
AW02_RS12485	COG0477	Major facilitator Superfamily
AW02_RS12490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW02_RS12495	COG2839	Protein conserved in bacteria
AW02_RS12500	COG5521	maltodextrose utilization protein MalA
AW02_RS12505	COG1388	LysM domain
AW02_RS12515	COG4709	membrane
AW02_RS12520	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AW02_RS12525	COG0735	belongs to the Fur family
AW02_RS12530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW02_RS12545	COG0513	Belongs to the DEAD box helicase family
AW02_RS12560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW02_RS12565	COG2384	SAM-dependent methyltransferase
AW02_RS12570	COG2010	Cytochrome c
AW02_RS12575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AW02_RS12580	COG0358	DNA primase activity
AW02_RS12595	COG0517	IMP dehydrogenase activity
AW02_RS12600	COG0751	glycine-tRNA ligase activity
AW02_RS12615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AW02_RS12620	COG0295	cytidine deaminase activity
AW02_RS12625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AW02_RS12635	COG1480	7TM receptor with intracellular HD hydrolase
AW02_RS12640	COG1702	phosphate starvation-inducible protein PhoH
AW02_RS12645	COG0561	phosphatase activity
AW02_RS12660	COG4864	UPF0365 protein
AW02_RS12665	COG1030	water channel activity
AW02_RS12670	COG1610	YqeY-like protein
AW02_RS12680	COG1283	sodium-dependent phosphate transmembrane transporter activity
AW02_RS12685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW02_RS12690	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AW02_RS12720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW02_RS12735	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW02_RS12750	COG1466	dna polymerase III delta subunit
AW02_RS12760	COG0658	competence protein
AW02_RS12760	COG2333	competence protein COMEC
AW02_RS12765	COG2131	deaminase
AW02_RS12770	COG1555	photosystem II stabilization
AW02_RS12770	COG1596	polysaccharide export
AW02_RS12775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW02_RS12780	COG2226	methyltransferase
AW02_RS12785	COG0799	negative regulation of ribosome biogenesis
AW02_RS12790	COG1713	HD superfamily hydrolase involved in NAD metabolism
AW02_RS12800	COG1534	Rna-binding protein
AW02_RS12805	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AW02_RS12810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW02_RS12815	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AW02_RS12825	COG2755	lipolytic protein G-D-S-L family
AW02_RS12835	COG0398	Pfam SNARE associated Golgi protein
AW02_RS12860	COG2207	Transcriptional regulator
AW02_RS12860	COG3708	Transcriptional regulator
AW02_RS12870	COG0563	adenylate kinase activity
AW02_RS12880	COG2814	Major facilitator Superfamily
AW02_RS12885	COG0456	acetyltransferase
AW02_RS12890	COG2318	DinB family
AW02_RS12900	COG0561	phosphatase activity
AW02_RS12905	COG0561	phosphatase activity
AW02_RS12915	COG1482	cell wall glycoprotein biosynthetic process
AW02_RS12920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW02_RS12920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW02_RS12920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW02_RS12925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW02_RS12925	COG3711	transcriptional antiterminator
AW02_RS12935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW02_RS12940	COG0583	DNA-binding transcription factor activity
AW02_RS12945	COG2814	Major facilitator Superfamily
AW02_RS12950	COG2124	cytochrome p450
AW02_RS12950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW02_RS12955	COG1309	transcriptional regulator
AW02_RS12960	COG2226	methyltransferase
AW02_RS12970	COG2116	formate transmembrane transporter activity
AW02_RS12975	COG5609	conserved protein (DUF2294)
AW02_RS12980	COG3383	formate dehydrogenase (NAD+) activity
AW02_RS12985	COG2427	Protein of unknown function (DUF1641)
AW02_RS12995	COG0626	cystathionine gamma-synthase activity
AW02_RS13000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW02_RS13025	COG0768	penicillin binding
AW02_RS13040	COG0826	peptidase U32
AW02_RS13045	COG0826	peptidase U32
AW02_RS13050	COG4122	O-methyltransferase activity
AW02_RS13055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW02_RS13070	COG4472	Bacterial protein of unknown function (DUF965)
AW02_RS13080	COG0628	permease
AW02_RS13085	COG1126	abc transporter atp-binding protein
AW02_RS13090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW02_RS13095	COG0765	amino acid transport
AW02_RS13100	COG0765	amino acid transport
AW02_RS13110	COG3881	PFAM PRC-barrel domain
AW02_RS13115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AW02_RS13120	COG0457	Tetratricopeptide repeat
AW02_RS13130	COG1104	cysteine desulfurase activity
AW02_RS13135	COG1959	2 iron, 2 sulfur cluster binding
AW02_RS13140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AW02_RS13145	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AW02_RS13160	COG4991	sh3 domain protein
AW02_RS13160	COG3103	Sh3 type 3 domain protein
AW02_RS13160	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW02_RS13170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW02_RS13180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AW02_RS13180	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AW02_RS13185	COG5416	Lipopolysaccharide assembly protein A domain
AW02_RS13190	COG0490	domain, Protein
AW02_RS13195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW02_RS13195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW02_RS13205	COG2244	polysaccharide biosynthetic process
AW02_RS13210	COG2323	membrane
AW02_RS13220	COG1862	Preprotein translocase
AW02_RS13265	COG1388	LysM domain
AW02_RS13275	COG0157	Belongs to the NadC ModD family
AW02_RS13280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AW02_RS13285	COG1104	cysteine desulfurase activity
AW02_RS13290	COG1827	regulation of RNA biosynthetic process
AW02_RS13295	COG0077	Prephenate dehydratase
AW02_RS13310	COG3290	protein histidine kinase activity
AW02_RS13315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AW02_RS13320	COG2868	ribosomal protein
AW02_RS13330	COG1994	Peptidase M50
AW02_RS13335	COG0739	heme binding
AW02_RS13340	COG2894	cell division
AW02_RS13350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AW02_RS13360	COG1077	Cell shape determining protein MreB Mrl
AW02_RS13380	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AW02_RS13385	COG0285	dihydrofolate synthase activity
AW02_RS13390	COG0525	valine-tRNA ligase activity
AW02_RS13400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW02_RS13405	COG1388	LysM domain
AW02_RS13415	COG0113	porphobilinogen synthase activity
AW02_RS13420	COG1587	Uroporphyrinogen-III synthase
AW02_RS13430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW02_RS13450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AW02_RS13455	COG1067	ATP-dependent peptidase activity
AW02_RS13455	COG0470	DNA polymerase III
AW02_RS13470	COG0457	Tetratricopeptide repeat
AW02_RS13470	COG1477	protein flavinylation
AW02_RS13485	COG0473	3-isopropylmalate dehydrogenase activity
AW02_RS13500	COG0440	acetolactate synthase activity
AW02_RS13505	COG0028	Belongs to the TPP enzyme family
AW02_RS13530	COG0622	Phosphoesterase
AW02_RS13535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AW02_RS13545	COG5401	PFAM Sporulation and spore germination
AW02_RS13555	COG1846	Transcriptional regulator
AW02_RS13560	COG2197	response regulator
AW02_RS13565	COG0824	Thioesterase
AW02_RS13570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AW02_RS13575	COG1053	succinate dehydrogenase
AW02_RS13580	COG2009	succinate dehydrogenase
AW02_RS13585	COG1719	4-vinyl reductase, 4VR
AW02_RS13590	COG0527	aspartate kinase activity
AW02_RS13600	COG3118	belongs to the thioredoxin family
AW02_RS13605	COG3534	alpha-L-arabinofuranosidase
AW02_RS13610	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AW02_RS13615	COG2086	electron transfer activity
AW02_RS13620	COG1024	Enoyl-CoA hydratase
AW02_RS13625	COG1309	transcriptional regulator
AW02_RS13630	COG0318	PFAM AMP-dependent synthetase and ligase
AW02_RS13640	COG3766	membrane
AW02_RS13650	COG1796	DNA polymerase
AW02_RS13650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW02_RS13655	COG1286	toxin biosynthetic process
AW02_RS13670	COG0072	phenylalanine-tRNA ligase activity
AW02_RS13670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW02_RS13675	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AW02_RS13680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW02_RS13690	COG3835	regulator
AW02_RS13695	COG0277	FAD linked oxidase domain protein
AW02_RS13700	COG0247	lactate metabolic process
AW02_RS13705	COG1966	Carbon starvation protein
AW02_RS13710	COG3534	alpha-L-arabinofuranosidase
AW02_RS13715	COG0395	ABC-type sugar transport system, permease component
AW02_RS13720	COG1175	transmembrane transport
AW02_RS13725	COG1653	transport
AW02_RS13735	COG0647	UMP catabolic process
AW02_RS13740	COG0235	Class ii aldolase
AW02_RS13745	COG1069	ribulokinase activity
AW02_RS13750	COG2160	L-arabinose isomerase activity
AW02_RS13755	COG3507	Belongs to the glycosyl hydrolase 43 family
AW02_RS13760	COG1363	Peptidase, m42
AW02_RS13770	COG3326	Membrane
AW02_RS13775	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AW02_RS13785	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AW02_RS13790	COG1346	cytolysis
AW02_RS13795	COG1380	Effector of murein hydrolase LrgA
AW02_RS13800	COG3279	Response regulator of the LytR AlgR family
AW02_RS13805	COG3275	phosphorelay sensor kinase activity
AW02_RS13810	COG1011	Hydrolase
AW02_RS13825	COG0398	Pfam SNARE associated Golgi protein
AW02_RS13830	COG1484	DNA-dependent DNA replication
AW02_RS13835	COG3611	Membrane attachment protein
AW02_RS13850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW02_RS13855	COG1733	regulation of RNA biosynthetic process
AW02_RS13860	COG2814	Major facilitator Superfamily
AW02_RS13865	COG0656	L-ascorbic acid biosynthetic process
AW02_RS13870	COG0237	dephospho-CoA kinase activity
AW02_RS13875	COG1971	Probably functions as a manganese efflux pump
AW02_RS13880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AW02_RS13885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW02_RS13885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW02_RS13890	COG5002	protein histidine kinase activity
AW02_RS13895	COG0745	RESPONSE REGULATOR receiver
AW02_RS13905	COG0538	isocitrate dehydrogenase activity
AW02_RS13910	COG0372	Belongs to the citrate synthase family
AW02_RS13925	COG0628	permease
AW02_RS13930	COG3030	protein affecting phage T7 exclusion by the F plasmid
AW02_RS13935	COG0469	pyruvate kinase activity
AW02_RS13960	COG0281	malic enzyme
AW02_RS13965	COG0587	DNA-directed DNA polymerase activity
AW02_RS13985	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AW02_RS13995	COG4109	DRTGG domain
AW02_RS14005	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS14020	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW02_RS14030	COG0827	DNA restriction-modification system
AW02_RS14035	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AW02_RS14040	COG3874	Sporulation protein YtfJ
AW02_RS14050	COG1714	RDD family
AW02_RS14055	COG0616	signal peptide processing
AW02_RS14060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AW02_RS14065	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AW02_RS14070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW02_RS14085	COG1104	cysteine desulfurase activity
AW02_RS14090	COG1114	Component of the transport system for branched-chain amino acids
AW02_RS14100	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW02_RS14105	COG1309	transcriptional regulator
AW02_RS14110	COG1956	GAF domain-containing protein
AW02_RS14115	COG2203	Gaf domain
AW02_RS14115	COG2199	diguanylate cyclase activity
AW02_RS14130	COG1012	belongs to the aldehyde dehydrogenase family
AW02_RS14135	COG4282	regulation of fungal-type cell wall biogenesis
AW02_RS14140	COG1017	nitric oxide dioxygenase activity
AW02_RS14140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW02_RS14150	COG0693	protein deglycase activity
AW02_RS14165	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW02_RS14170	COG1378	Sugar-specific transcriptional regulator TrmB
AW02_RS14190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW02_RS14195	COG0454	-acetyltransferase
AW02_RS14200	COG0517	IMP dehydrogenase activity
AW02_RS14205	COG0123	including yeast histone deacetylase and acetoin utilization protein
AW02_RS14210	COG1360	Flagellar Motor Protein
AW02_RS14215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW02_RS14220	COG1609	Transcriptional regulator
AW02_RS14225	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AW02_RS14225	COG1605	Chorismate mutase
AW02_RS14230	COG3118	belongs to the thioredoxin family
AW02_RS14235	COG4980	gas vesicle protein
AW02_RS14240	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AW02_RS14250	COG1674	ftsk spoiiie
AW02_RS14255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW02_RS14265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW02_RS14275	COG1363	Peptidase, m42
AW02_RS14280	COG5584	Small secreted protein
AW02_RS14285	COG0281	malic enzyme
AW02_RS14290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW02_RS14305	COG0510	thiamine kinase activity
AW02_RS14310	COG1597	lipid kinase activity
AW02_RS14320	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AW02_RS14325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW02_RS14330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW02_RS14335	COG2252	PERMEase
AW02_RS14340	COG4473	ABC transporter
AW02_RS14345	COG1131	(ABC) transporter
AW02_RS14350	COG1349	DNA-binding transcription factor activity
AW02_RS14355	COG1187	pseudouridine synthase activity
AW02_RS14360	COG2244	polysaccharide biosynthetic process
AW02_RS14365	COG2081	HI0933 family
AW02_RS14370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW02_RS14380	COG1609	Transcriptional regulator
AW02_RS14385	COG1653	transport
AW02_RS14390	COG1175	transmembrane transport
AW02_RS14395	COG0395	ABC-type sugar transport system, permease component
AW02_RS14400	COG1486	melibiose metabolic process
AW02_RS14410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW02_RS14425	COG1366	Belongs to the anti-sigma-factor antagonist family
AW02_RS14425	COG2202	Pas domain
AW02_RS14430	COG2814	Major facilitator Superfamily
AW02_RS14435	COG5522	Integral membrane protein (intg_mem_TP0381)
AW02_RS14440	COG0577	efflux transmembrane transporter activity
AW02_RS14445	COG1136	(ABC) transporter
AW02_RS14450	COG2205	protein histidine kinase activity
AW02_RS14455	COG0745	RESPONSE REGULATOR receiver
AW02_RS14460	COG0577	efflux transmembrane transporter activity
AW02_RS14465	COG1136	(ABC) transporter
AW02_RS14485	COG1131	(ABC) transporter
AW02_RS14490	COG1725	Transcriptional regulator
AW02_RS14500	COG0640	Transcriptional regulator
AW02_RS14505	COG0477	Major facilitator Superfamily
AW02_RS14510	COG1242	4 iron, 4 sulfur cluster binding
AW02_RS14515	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AW02_RS14525	COG0584	glycerophosphoryl diester phosphodiesterase
AW02_RS14535	COG2267	carboxylic ester hydrolase activity
AW02_RS14540	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW02_RS14545	COG1113	amino acid transport
AW02_RS14550	COG0367	asparagine synthase
AW02_RS14570	COG1506	peptidase
AW02_RS14575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW02_RS14580	COG1116	anion transmembrane transporter activity
AW02_RS14585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW02_RS14590	COG0494	nUDIX hydrolase
AW02_RS14595	COG4824	toxin secretion phage lysis holin
AW02_RS14600	COG0783	Belongs to the Dps family
AW02_RS14625	COG0288	reversible hydration of carbon dioxide
AW02_RS14635	COG1271	oxidase subunit
AW02_RS14640	COG1294	oxidase, subunit
AW02_RS14645	COG4948	Mandelate Racemase Muconate Lactonizing
AW02_RS14655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AW02_RS14660	COG0596	Alpha beta hydrolase
AW02_RS14670	COG1169	isochorismate synthase
AW02_RS14675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW02_RS14680	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AW02_RS14805	COG3859	Proton-coupled thiamine transporter YuaJ
AW02_RS14810	COG2268	Band 7 protein
AW02_RS14815	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW02_RS14820	COG2318	DinB family
AW02_RS14830	COG1454	alcohol dehydrogenase
AW02_RS14835	COG1012	belongs to the aldehyde dehydrogenase family
AW02_RS14840	COG1510	regulation of RNA biosynthetic process
AW02_RS14850	COG0569	domain protein
AW02_RS14855	COG1705	Flagellar rod assembly protein muramidase FlgJ
AW02_RS14860	COG1017	nitric oxide dioxygenase activity
AW02_RS14860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW02_RS14885	COG0628	permease
AW02_RS14890	COG0673	inositol 2-dehydrogenase activity
AW02_RS14895	COG0693	protein deglycase activity
AW02_RS14900	COG0840	transmembrane signaling receptor activity
AW02_RS14905	COG0840	transmembrane signaling receptor activity
AW02_RS14910	COG0840	transmembrane signaling receptor activity
AW02_RS14915	COG0840	transmembrane signaling receptor activity
AW02_RS14930	COG2070	2-Nitropropane dioxygenase
AW02_RS14935	COG0432	Pfam Uncharacterised protein family UPF0047
AW02_RS14940	COG0366	Alpha amylase catalytic
AW02_RS14945	COG1253	flavin adenine dinucleotide binding
AW02_RS14950	COG2738	Putative neutral zinc metallopeptidase
AW02_RS14965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW02_RS14990	COG1335	isochorismatase
AW02_RS14995	COG1979	alcohol dehydrogenase
AW02_RS15000	COG1979	alcohol dehydrogenase
AW02_RS15005	COG2155	Conserved Protein
AW02_RS15010	COG1098	S1 RNA binding domain
AW02_RS15015	COG0436	Aminotransferase
AW02_RS15020	COG1522	sequence-specific DNA binding
AW02_RS15025	COG2267	carboxylic ester hydrolase activity
AW02_RS15035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW02_RS15040	COG2205	protein histidine kinase activity
AW02_RS15050	COG5018	Exonuclease
AW02_RS15055	COG2814	Major facilitator Superfamily
AW02_RS15060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW02_RS15065	COG3011	Protein conserved in bacteria
AW02_RS15075	COG3290	protein histidine kinase activity
AW02_RS15080	COG4565	transcriptional regulatory protein
AW02_RS15085	COG1744	ABC transporter substrate-binding protein PnrA-like
AW02_RS15090	COG3845	ABC transporter
AW02_RS15095	COG4603	Belongs to the binding-protein-dependent transport system permease family
AW02_RS15100	COG1079	Belongs to the binding-protein-dependent transport system permease family
AW02_RS15110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW02_RS15110	COG2111	Na H antiporter
AW02_RS15115	COG2111	Na H antiporter
AW02_RS15120	COG1006	Multisubunit Na H antiporter MnhC subunit
AW02_RS15125	COG0651	ATP synthesis coupled electron transport
AW02_RS15130	COG1863	multisubunit Na H antiporter MnhE subunit
AW02_RS15135	COG2212	antiporter activity
AW02_RS15140	COG1320	monovalent cation:proton antiporter activity
AW02_RS15145	COG2050	protein possibly involved in aromatic compounds catabolism
AW02_RS15150	COG2197	response regulator
AW02_RS15155	COG4585	Histidine kinase
AW02_RS15165	COG0142	geranyltranstransferase activity
AW02_RS15180	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AW02_RS15185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AW02_RS15190	COG1335	isochorismatase
AW02_RS15195	COG5506	Protein of unknown function (DUF1694)
AW02_RS15210	COG0628	permease
AW02_RS15220	COG1418	mRNA catabolic process
AW02_RS15225	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS15235	COG1511	domain protein
AW02_RS15240	COG1674	ftsk spoiiie
AW02_RS15240	COG0433	COG0433 Predicted ATPase
AW02_RS15245	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW02_RS15250	COG5417	Belongs to the EsaB family
AW02_RS15255	COG4842	Belongs to the WXG100 family
AW02_RS15260	COG2508	Transcriptional regulator
AW02_RS15260	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AW02_RS15265	COG0686	Belongs to the AlaDH PNT family
AW02_RS15270	COG5634	Uncharacterized conserved protein (DUF2278)
AW02_RS15275	COG3251	PFAM MbtH domain protein
AW02_RS15280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW02_RS15285	COG3433	isochorismatase activity
AW02_RS15285	COG1535	isochorismatase
AW02_RS15290	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW02_RS15295	COG1169	isochorismate synthase
AW02_RS15300	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS15305	COG2819	hydrolase of the alpha beta superfamily
AW02_RS15310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW02_RS15315	COG1268	BioY protein
AW02_RS15320	COG2056	Na+-H+ antiporter family
AW02_RS15330	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AW02_RS15335	COG3584	3D domain protein
AW02_RS15345	COG1252	NADH dehydrogenase
AW02_RS15370	COG1131	(ABC) transporter
AW02_RS15395	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AW02_RS15400	COG0316	Belongs to the HesB IscA family
AW02_RS15410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW02_RS15420	COG1252	NADH dehydrogenase
AW02_RS15425	COG4837	Protein of unknown function (DUF1462)
AW02_RS15430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AW02_RS15435	COG1506	peptidase
AW02_RS15435	COG0823	Involved in the tonB-independent uptake of proteins
AW02_RS15435	COG4946	Tricorn protease homolog
AW02_RS15445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AW02_RS15450	COG0460	homoserine dehydrogenase
AW02_RS15455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW02_RS15460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW02_RS15465	COG0647	UMP catabolic process
AW02_RS15470	COG2445	Protein of unknown function DUF86
AW02_RS15475	COG4470	Protein conserved in bacteria
AW02_RS15485	COG0739	heme binding
AW02_RS15495	COG0737	Belongs to the 5'-nucleotidase family
AW02_RS15500	COG0730	response to heat
AW02_RS15505	COG1801	Protein of unknown function DUF72
AW02_RS15520	COG2508	Transcriptional regulator
AW02_RS15525	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AW02_RS15540	COG2814	Major facilitator Superfamily
AW02_RS15545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AW02_RS15550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW02_RS15555	COG2356	endonuclease I
AW02_RS15560	COG3842	ATPase activity
AW02_RS15565	COG2188	Transcriptional regulator
AW02_RS15570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW02_RS15575	COG0395	ABC-type sugar transport system, permease component
AW02_RS15580	COG1175	transmembrane transport
AW02_RS15585	COG1653	transport
AW02_RS15590	COG2222	sugar isomerase
AW02_RS15595	COG0789	Transcriptional regulator
AW02_RS15605	COG0322	excinuclease ABC activity
AW02_RS15610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW02_RS15615	COG2226	methyltransferase
AW02_RS15625	COG3409	Peptidoglycan-binding domain 1 protein
AW02_RS15630	COG0719	Fe-S assembly protein
AW02_RS15635	COG0822	iron-sulfur transferase activity
AW02_RS15640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW02_RS15645	COG0719	Fe-S assembly protein
AW02_RS15650	COG0396	ATPase activity
AW02_RS15655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW02_RS15660	COG1464	Belongs to the NlpA lipoprotein family
AW02_RS15665	COG2011	ABC-type metal ion transport system permease component
AW02_RS15670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW02_RS15680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW02_RS15685	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW02_RS15700	COG1393	Belongs to the ArsC family
AW02_RS15705	COG1960	acyl-CoA dehydrogenase activity
AW02_RS15710	COG0183	Belongs to the thiolase family
AW02_RS15715	COG1024	Enoyl-CoA hydratase
AW02_RS15715	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW02_RS15730	COG0477	Major facilitator Superfamily
AW02_RS15740	COG5577	PFAM Coat F domain
AW02_RS15745	COG1846	Transcriptional regulator
AW02_RS15750	COG0477	Major facilitator Superfamily
AW02_RS15755	COG0583	DNA-binding transcription factor activity
AW02_RS15775	COG1120	ATPase activity
AW02_RS15790	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS15795	COG0783	Belongs to the Dps family
AW02_RS15800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW02_RS15805	COG0745	RESPONSE REGULATOR receiver
AW02_RS15810	COG2205	protein histidine kinase activity
AW02_RS15810	COG2770	Histidine kinase
AW02_RS15815	COG1309	transcriptional regulator
AW02_RS15820	COG0114	fumarate hydratase activity
AW02_RS15830	COG0697	spore germination
AW02_RS15835	COG0814	amino acid
AW02_RS15845	COG2197	response regulator
AW02_RS15850	COG4585	Histidine kinase
AW02_RS15855	COG4758	membrane
AW02_RS15860	COG3595	metallopeptidase activity
AW02_RS15865	COG1842	Phage shock protein A
AW02_RS15870	COG4758	membrane
AW02_RS15875	COG2814	Major facilitator Superfamily
AW02_RS15880	COG2096	Adenosyltransferase
AW02_RS15885	COG1120	ATPase activity
AW02_RS15890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW02_RS15895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW02_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS15905	COG3386	PFAM SMP-30 Gluconolaconase
AW02_RS15910	COG2205	protein histidine kinase activity
AW02_RS15915	COG0745	RESPONSE REGULATOR receiver
AW02_RS15925	COG1191	sigma factor activity
AW02_RS15930	COG2140	Oxalate decarboxylase
AW02_RS15940	COG1120	ATPase activity
AW02_RS15945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW02_RS15950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW02_RS15955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW02_RS15960	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AW02_RS15965	COG0531	amino acid
AW02_RS15975	COG1988	membrane-bound metal-dependent
AW02_RS15980	COG1368	sulfuric ester hydrolase activity
AW02_RS15985	COG1910	domain protein
AW02_RS15990	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW02_RS15995	COG4149	molybdate abc transporter
AW02_RS16000	COG2197	response regulator
AW02_RS16005	COG3850	Histidine kinase
AW02_RS16010	COG1131	(ABC) transporter
AW02_RS16020	COG0842	Transport permease protein
AW02_RS16025	COG0656	L-ascorbic acid biosynthetic process
AW02_RS16050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW02_RS16055	COG3973	AAA domain
AW02_RS16060	COG2860	membrane
AW02_RS16070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AW02_RS16075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW02_RS16080	COG2217	Heavy metal translocating P-type atpase
AW02_RS16085	COG2217	Heavy metal translocating P-type atpase
AW02_RS16090	COG2608	mercury ion transmembrane transporter activity
AW02_RS16095	COG1937	Protein conserved in bacteria
AW02_RS16100	COG0673	inositol 2-dehydrogenase activity
AW02_RS16115	COG2814	Major facilitator Superfamily
AW02_RS16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW02_RS16135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AW02_RS16140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW02_RS16145	COG1126	abc transporter atp-binding protein
AW02_RS16150	COG0765	amino acid transport
AW02_RS16155	COG0765	amino acid transport
AW02_RS16160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW02_RS16165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW02_RS16170	COG0454	-acetyltransferase
AW02_RS16175	COG0583	DNA-binding transcription factor activity
AW02_RS16180	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS16185	COG2732	(Barnase) inhibitor
AW02_RS16195	COG0557	exoribonuclease II activity
AW02_RS16200	COG1647	Serine aminopeptidase, S33
AW02_RS16205	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW02_RS16210	COG1476	TRANSCRIPTIONal
AW02_RS16215	COG1396	sequence-specific DNA binding
AW02_RS16220	COG1396	sequence-specific DNA binding
AW02_RS16225	COG1733	regulation of RNA biosynthetic process
AW02_RS16250	COG1131	(ABC) transporter
AW02_RS16255	COG1174	glycine betaine transport
AW02_RS16260	COG1732	Glycine betaine
AW02_RS16265	COG1174	glycine betaine transport
AW02_RS16270	COG0517	IMP dehydrogenase activity
AW02_RS16270	COG1125	glycine betaine transport
AW02_RS16275	COG1510	regulation of RNA biosynthetic process
AW02_RS16280	COG1174	glycine betaine transport
AW02_RS16285	COG1732	Glycine betaine
AW02_RS16290	COG1174	glycine betaine transport
AW02_RS16295	COG1125	glycine betaine transport
AW02_RS16295	COG0517	IMP dehydrogenase activity
AW02_RS16300	COG1510	regulation of RNA biosynthetic process
AW02_RS16305	COG2095	MarC family integral membrane protein
AW02_RS16310	COG3064	Membrane
AW02_RS16315	COG4640	response to antibiotic
AW02_RS16320	COG0456	acetyltransferase
AW02_RS16335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW02_RS16350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW02_RS16355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW02_RS16360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW02_RS16370	COG2234	aminopeptidase activity
AW02_RS16390	COG0126	phosphoglycerate kinase activity
AW02_RS16400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW02_RS16405	COG2390	Transcriptional regulator
AW02_RS16410	COG2814	Major facilitator Superfamily
AW02_RS16415	COG1609	Transcriptional regulator
AW02_RS16420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW02_RS16430	COG0583	DNA-binding transcription factor activity
AW02_RS16435	COG0697	spore germination
AW02_RS16440	COG1113	amino acid transport
AW02_RS16445	COG1737	Transcriptional regulator
AW02_RS16450	COG1070	Carbohydrate kinase
AW02_RS16475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW02_RS16480	COG2186	Transcriptional regulator
AW02_RS16485	COG1620	l-lactate permease
AW02_RS16490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AW02_RS16500	COG5039	Polysaccharide pyruvyl transferase
AW02_RS16505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW02_RS16510	COG0110	maltose O-acetyltransferase activity
AW02_RS16515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AW02_RS16520	COG2244	polysaccharide biosynthetic process
AW02_RS16525	COG1216	Glycosyl transferase, family 2
AW02_RS16530	COG5039	Polysaccharide pyruvyl transferase
AW02_RS16535	COG1216	Glycosyl transferase, family 2
AW02_RS16545	COG0438	transferase activity, transferring glycosyl groups
AW02_RS16550	COG1215	transferase activity, transferring glycosyl groups
AW02_RS16555	COG0438	transferase activity, transferring glycosyl groups
AW02_RS16560	COG1086	Polysaccharide biosynthesis protein
AW02_RS16565	COG0489	protein tyrosine kinase activity
AW02_RS16570	COG3944	biosynthesis protein
AW02_RS16575	COG1396	sequence-specific DNA binding
AW02_RS16580	COG2272	Belongs to the type-B carboxylesterase lipase family
AW02_RS16590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW02_RS16595	COG2364	Membrane
AW02_RS16600	COG0456	acetyltransferase
AW02_RS16605	COG3479	Phenolic acid decarboxylase
AW02_RS16655	COG2223	nitrite transmembrane transporter activity
AW02_RS16660	COG1609	Transcriptional regulator
AW02_RS16670	COG0583	DNA-binding transcription factor activity
AW02_RS16675	COG2828	Protein conserved in bacteria
AW02_RS16680	COG2814	Major facilitator Superfamily
AW02_RS16680	COG0477	Major facilitator Superfamily
AW02_RS16685	COG1611	Belongs to the LOG family
AW02_RS16690	COG1694	Mazg nucleotide pyrophosphohydrolase
AW02_RS16695	COG0659	secondary active sulfate transmembrane transporter activity
AW02_RS16700	COG0288	reversible hydration of carbon dioxide
AW02_RS16710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW02_RS16715	COG4290	ribonuclease
AW02_RS16720	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AW02_RS16725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW02_RS16735	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AW02_RS16745	COG1051	belongs to the nudix hydrolase family
AW02_RS16750	COG0492	ferredoxin-NADP+ reductase activity
AW02_RS16755	COG3883	PFAM NLP P60 protein
AW02_RS16755	COG0791	NLP P60 protein
AW02_RS16760	COG0457	Tetratricopeptide repeat
AW02_RS16765	COG5002	protein histidine kinase activity
AW02_RS16770	COG0745	RESPONSE REGULATOR receiver
AW02_RS16780	COG1132	(ABC) transporter
AW02_RS16785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AW02_RS16785	COG0140	phosphoribosyl-ATP diphosphatase activity
AW02_RS16810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AW02_RS16825	COG4990	cell redox homeostasis
AW02_RS16830	COG0110	maltose O-acetyltransferase activity
AW02_RS16850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW02_RS16860	COG2188	Transcriptional regulator
AW02_RS16865	COG1309	transcriptional regulator
AW02_RS16870	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AW02_RS16875	COG1950	PFAM Membrane protein of
AW02_RS16880	COG1983	PspC domain protein
AW02_RS16885	COG3595	metallopeptidase activity
AW02_RS16900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW02_RS16910	COG4897	Protein conserved in bacteria
AW02_RS16915	COG3848	Pyruvate phosphate dikinase
AW02_RS16915	COG0574	Belongs to the PEP-utilizing enzyme family
AW02_RS16920	COG1309	transcriptional regulator
AW02_RS16925	COG2814	Major facilitator Superfamily
AW02_RS16935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW02_RS16945	COG0793	Belongs to the peptidase S41A family
AW02_RS16945	COG3409	Peptidoglycan-binding domain 1 protein
AW02_RS16950	COG3420	alginic acid biosynthetic process
AW02_RS16955	COG2177	Part of the ABC transporter FtsEX involved in
AW02_RS16960	COG2884	Cell division ATP-binding protein ftsE
AW02_RS16965	COG2010	Cytochrome c
AW02_RS16970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW02_RS16975	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AW02_RS16985	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AW02_RS17000	COG1516	flagellar protein fliS
AW02_RS17005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AW02_RS17010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW02_RS17030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW02_RS17035	COG4786	Flagellar basal body rod
AW02_RS17035	COG1256	bacterial-type flagellum assembly
AW02_RS17040	COG3418	PFAM FlgN family protein
AW02_RS17045	COG2747	anti-sigma28 factor FlgM
AW02_RS17055	COG1040	competence protein
AW02_RS17065	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AW02_RS17070	COG1307	EDD domain protein, DegV family
AW02_RS17075	COG2197	response regulator
AW02_RS17080	COG4585	Histidine kinase
AW02_RS17085	COG1739	Uncharacterized protein family UPF0029
AW02_RS17090	COG1316	TRANSCRIPTIONal
AW02_RS17095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW02_RS17100	COG0438	transferase activity, transferring glycosyl groups
AW02_RS17105	COG1215	transferase activity, transferring glycosyl groups
AW02_RS17110	COG3206	protein involved in exopolysaccharide biosynthesis
AW02_RS17115	COG3307	-O-antigen
AW02_RS17120	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW02_RS17125	COG0438	transferase activity, transferring glycosyl groups
AW02_RS17125	COG0297	glycogen (starch) synthase activity
AW02_RS17130	COG2244	polysaccharide biosynthetic process
AW02_RS17140	COG2247	cell wall binding repeat
AW02_RS17140	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW02_RS17145	COG2385	sporulation resulting in formation of a cellular spore
AW02_RS17145	COG2247	cell wall binding repeat
AW02_RS17155	COG1316	TRANSCRIPTIONal
AW02_RS17160	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW02_RS17165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW02_RS17170	COG1134	teichoic acid transport
AW02_RS17175	COG1682	transport, permease protein
AW02_RS17180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AW02_RS17190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AW02_RS17195	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AW02_RS17200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AW02_RS17205	COG4193	domain, Protein
AW02_RS17210	COG1482	cell wall glycoprotein biosynthetic process
AW02_RS17215	COG0697	spore germination
AW02_RS17220	COG0814	amino acid
AW02_RS17230	COG1215	transferase activity, transferring glycosyl groups
AW02_RS17235	COG2814	Major facilitator Superfamily
AW02_RS17240	COG1316	TRANSCRIPTIONal
AW02_RS17245	COG0561	phosphatase activity
AW02_RS17250	COG2433	Pfam Transposase IS66
AW02_RS17255	COG0791	NLP P60 protein
AW02_RS17260	COG2843	Capsule synthesis protein
AW02_RS17270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AW02_RS17275	COG0697	spore germination
AW02_RS17280	COG0814	amino acid
AW02_RS17290	COG1609	Transcriptional regulator
AW02_RS17295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW02_RS17305	COG1129	ABC transporter
AW02_RS17310	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW02_RS17315	COG1879	ABC-type sugar transport system periplasmic component
AW02_RS17320	COG3103	Sh3 type 3 domain protein
AW02_RS17325	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW02_RS17330	COG3527	Alpha-acetolactate decarboxylase
AW02_RS17335	COG0028	Belongs to the TPP enzyme family
AW02_RS17340	COG0583	DNA-binding transcription factor activity
AW02_RS17345	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW02_RS17360	COG5337	Spore coat protein CotH
AW02_RS17370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AW02_RS17380	COG0405	Gamma-glutamyltransferase
AW02_RS17385	COG1522	sequence-specific DNA binding
AW02_RS17390	COG2059	Chromate
AW02_RS17395	COG2059	Chromate
AW02_RS17405	COG0655	NAD(P)H dehydrogenase (quinone) activity
AW02_RS17410	COG0583	DNA-binding transcription factor activity
AW02_RS17430	COG5444	nuclease activity
AW02_RS17450	COG5444	nuclease activity
AW02_RS17465	COG3878	Protein conserved in bacteria
AW02_RS17470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW02_RS17475	COG4464	protein tyrosine phosphatase activity
AW02_RS17480	COG0489	protein tyrosine kinase activity
AW02_RS17485	COG3944	biosynthesis protein
AW02_RS17495	COG4715	Zinc finger, swim domain protein
AW02_RS17500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW02_RS17505	COG0561	phosphatase activity
AW02_RS17510	COG1349	DNA-binding transcription factor activity
AW02_RS17515	COG0629	single-stranded DNA binding
AW02_RS17540	COG0457	Tetratricopeptide repeat
AW02_RS17545	COG4786	Flagellar basal body rod
AW02_RS17550	COG4786	Flagellar basal body rod
AW02_RS17555	COG1077	Cell shape determining protein MreB Mrl
AW02_RS17560	COG1609	Transcriptional regulator
AW02_RS17565	COG1846	Transcriptional regulator
AW02_RS17570	COG2814	Major facilitator Superfamily
AW02_RS17575	COG1953	Uracil, thiamine, allantoin
AW02_RS17580	COG0477	Major facilitator Superfamily
AW02_RS17585	COG1335	isochorismatase
AW02_RS17590	COG0004	ammonium transporteR
AW02_RS17595	COG0347	Belongs to the P(II) protein family
AW02_RS17600	COG0772	Belongs to the SEDS family
AW02_RS17605	COG0671	phosphoesterase, PA-phosphatase related
AW02_RS17615	COG0739	heme binding
AW02_RS17620	COG1247	-acetyltransferase
AW02_RS17635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW02_RS17645	COG0726	polysaccharide deacetylase
AW02_RS17655	COG1959	2 iron, 2 sulfur cluster binding
AW02_RS17670	COG0831	urea catabolic process
AW02_RS17675	COG3237	CsbD-like
AW02_RS17680	COG1994	Peptidase M50
AW02_RS17685	COG0457	Tetratricopeptide repeat
AW02_RS17695	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW02_RS17700	COG2304	oxidoreductase activity
AW02_RS17705	COG2304	oxidoreductase activity
AW02_RS17710	COG2385	sporulation resulting in formation of a cellular spore
AW02_RS17715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AW02_RS17725	COG4836	Membrane
AW02_RS17795	COG0698	ribose 5-phosphate isomerase
AW02_RS17800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW02_RS17810	COG0009	L-threonylcarbamoyladenylate synthase
AW02_RS17815	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AW02_RS17835	COG2890	protein-(glutamine-N5) methyltransferase activity
AW02_RS17840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AW02_RS17845	COG0346	lactoylglutathione lyase activity
AW02_RS17850	COG0789	Transcriptional regulator
AW02_RS17855	COG0679	Auxin Efflux Carrier
AW02_RS17860	COG0281	malic enzyme
AW02_RS17875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AW02_RS17880	COG1494	fructose-1,6-bisphosphatase
AW02_RS17885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AW02_RS17895	COG0191	fructose-bisphosphate aldolase activity
AW02_RS17900	COG2204	response regulator
AW02_RS17905	COG4821	SIS domain
AW02_RS17920	COG2181	nitrate reductase activity
AW02_RS17920	COG0247	lactate metabolic process
AW02_RS17925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW02_RS17940	COG1132	(ABC) transporter
AW02_RS17945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW02_RS17955	COG2181	nitrate reductase activity
AW02_RS17960	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AW02_RS17965	COG1140	nitrate reductase beta subunit
AW02_RS17970	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AW02_RS17975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW02_RS17985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW02_RS17990	COG2223	nitrite transmembrane transporter activity
AW02_RS18000	COG4506	Protein conserved in bacteria
AW02_RS18005	COG0457	Tetratricopeptide repeat
AW02_RS18010	COG0010	Belongs to the arginase family
AW02_RS18035	COG0018	arginyl-trna synthetase
AW02_RS18040	COG0010	Belongs to the arginase family
AW02_RS18045	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AW02_RS18050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW02_RS18065	COG1994	Peptidase M50
AW02_RS18070	COG1942	4-Oxalocrotonate Tautomerase
AW02_RS18075	COG1846	Transcriptional regulator
AW02_RS18085	COG0531	amino acid
AW02_RS18090	COG3465	dGTPase activity
AW02_RS18095	COG1078	dGTPase activity
AW02_RS18110	COG1695	Transcriptional regulator
AW02_RS18125	COG0583	DNA-binding transcription factor activity
AW02_RS18130	COG2855	membrane
AW02_RS18135	COG0280	phosphate acetyltransferase
AW02_RS18145	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS18150	COG0436	Aminotransferase
AW02_RS18180	COG2814	Major facilitator Superfamily
AW02_RS18185	COG2814	Major facilitator Superfamily
AW02_RS18190	COG0833	amino acid
AW02_RS18195	COG4187	Peptidase family M20/M25/M40
AW02_RS18200	COG1012	belongs to the aldehyde dehydrogenase family
AW02_RS18205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW02_RS18215	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AW02_RS18220	COG1091	dTDP-4-dehydrorhamnose reductase activity
AW02_RS18225	COG1088	dTDP-glucose 4,6-dehydratase activity
AW02_RS18230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AW02_RS18235	COG3980	spore coat polysaccharide biosynthesis protein
AW02_RS18240	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AW02_RS18245	COG2089	acid synthase
AW02_RS18250	COG0456	acetyltransferase
AW02_RS18255	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW02_RS18260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AW02_RS18265	COG0463	Glycosyl transferase, family 2
AW02_RS18275	COG2363	Small membrane protein
AW02_RS18280	COG2233	PERMEase
AW02_RS18295	COG1216	Glycosyl transferase, family 2
AW02_RS18310	COG1695	Transcriptional regulator
AW02_RS18315	COG0351	phosphomethylpyrimidine kinase
AW02_RS18325	COG1621	beta-fructofuranosidase activity
AW02_RS18330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW02_RS18330	COG1263	PTS System
AW02_RS18335	COG3711	transcriptional antiterminator
AW02_RS18345	COG1404	Belongs to the peptidase S8 family
AW02_RS18350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW02_RS18355	COG0778	Nitroreductase
AW02_RS18360	COG0772	Belongs to the SEDS family
AW02_RS18365	COG0454	-acetyltransferase
AW02_RS18385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW02_RS18390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW02_RS18395	COG2261	transglycosylase associated protein
AW02_RS18400	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AW02_RS18405	COG2246	polysaccharide biosynthetic process
AW02_RS18410	COG1309	transcriptional regulator
AW02_RS18430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW02_RS18435	COG2837	iron assimilation
AW02_RS18455	COG0583	DNA-binding transcription factor activity
AW02_RS18465	COG1346	cytolysis
AW02_RS18470	COG4895	conserved protein (DUF2196)
AW02_RS18475	COG0789	Transcriptional regulator
AW02_RS18480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AW02_RS18485	COG0346	lactoylglutathione lyase activity
AW02_RS18490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW02_RS18495	COG1404	Belongs to the peptidase S8 family
AW02_RS18500	COG1442	glycosyl transferase family 8
AW02_RS18505	COG2357	RelA SpoT domain protein
AW02_RS18510	COG1575	Belongs to the MenA family. Type 1 subfamily
AW02_RS18525	COG1696	Membrane protein involved in D-alanine export
AW02_RS18535	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW02_RS18540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW02_RS18545	COG1486	melibiose metabolic process
AW02_RS18550	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW02_RS18555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW02_RS18560	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW02_RS18565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW02_RS18565	COG3711	transcriptional antiterminator
AW02_RS18575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW02_RS18580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW02_RS18590	COG0640	Transcriptional regulator
AW02_RS18595	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW02_RS18600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW02_RS18605	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW02_RS18610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW02_RS18615	COG2723	6-phospho-beta-galactosidase activity
AW02_RS18620	COG1940	carbohydrate kinase activity
AW02_RS18625	COG1482	cell wall glycoprotein biosynthetic process
AW02_RS18635	COG0753	catalase activity
AW02_RS18640	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AW02_RS18645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AW02_RS18650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AW02_RS18655	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AW02_RS18660	COG4988	ABC transporter
AW02_RS18665	COG1294	oxidase, subunit
AW02_RS18670	COG1271	oxidase subunit
AW02_RS18675	COG3493	citrate carrier protein
AW02_RS18680	COG0726	polysaccharide deacetylase
AW02_RS18685	COG3842	ATPase activity
AW02_RS18690	COG2508	Transcriptional regulator
AW02_RS18695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW02_RS18705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW02_RS18715	COG4894	glucomannan catabolic process
AW02_RS18720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AW02_RS18725	COG0500	methyltransferase
AW02_RS18730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW02_RS18745	COG0693	protein deglycase activity
AW02_RS18745	COG0753	catalase activity
AW02_RS18750	COG2851	Citrate transporter
AW02_RS18755	COG2273	Hydrolase Family 16
AW02_RS18765	COG2270	Major facilitator Superfamily
AW02_RS18770	COG0513	Belongs to the DEAD box helicase family
AW02_RS18835	COG0697	spore germination
AW02_RS18840	COG0589	response to stress
AW02_RS18890	COG3507	Belongs to the glycosyl hydrolase 43 family
AW02_RS18915	COG0010	Belongs to the arginase family
AW02_RS18920	COG0833	amino acid
AW02_RS18925	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AW02_RS18930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW02_RS18940	COG2390	Transcriptional regulator
AW02_RS18945	COG0561	phosphatase activity
AW02_RS18975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW02_RS18980	COG5294	Protein conserved in bacteria
AW02_RS18985	COG0577	efflux transmembrane transporter activity
AW02_RS18990	COG1136	(ABC) transporter
AW02_RS18995	COG2205	protein histidine kinase activity
AW02_RS19000	COG0745	RESPONSE REGULATOR receiver
AW02_RS19015	COG1082	Xylose isomerase domain protein TIM barrel
AW02_RS19025	COG2814	Major facilitator Superfamily
AW02_RS19055	COG1349	DNA-binding transcription factor activity
AW02_RS19060	COG0667	Aldo Keto reductase
AW02_RS19065	COG2814	Major facilitator Superfamily
AW02_RS19080	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS19085	COG2197	response regulator
AW02_RS19090	COG4585	Histidine kinase
AW02_RS19095	COG3239	Fatty acid desaturase
AW02_RS19105	COG1309	transcriptional regulator
AW02_RS19110	COG1012	belongs to the aldehyde dehydrogenase family
AW02_RS19115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AW02_RS19125	COG0640	Transcriptional regulator
AW02_RS19130	COG2814	Major facilitator Superfamily
AW02_RS19135	COG1714	RDD family
AW02_RS19145	COG0450	alkyl hydroperoxide reductase
AW02_RS19150	COG3634	alkyl hydroperoxide reductase activity
AW02_RS19155	COG1113	amino acid transport
AW02_RS19165	COG2080	2 iron, 2 sulfur cluster binding
AW02_RS19180	COG2068	MobA-Related Protein
AW02_RS19185	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AW02_RS19220	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AW02_RS19225	COG0667	Aldo Keto reductase
AW02_RS19230	COG0456	acetyltransferase
AW02_RS19235	COG0457	Tetratricopeptide repeat
AW02_RS19240	COG0010	Belongs to the arginase family
AW02_RS19245	COG0833	amino acid
AW02_RS19250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW02_RS19255	COG3829	transcription factor binding
AW02_RS19265	COG0488	(ABC) transporter
AW02_RS19280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW02_RS19285	COG5002	protein histidine kinase activity
AW02_RS19285	COG3850	Histidine kinase
AW02_RS19295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW02_RS19300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AW02_RS19305	COG4853	Protein conserved in bacteria
AW02_RS19310	COG4863	YycH protein
AW02_RS19315	COG5002	protein histidine kinase activity
AW02_RS19320	COG0745	RESPONSE REGULATOR receiver
AW02_RS19355	COG0346	lactoylglutathione lyase activity
AW02_RS19360	COG0305	Participates in initiation and elongation during chromosome replication
AW02_RS19375	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AW02_RS19380	COG0297	glycogen (starch) synthase activity
AW02_RS19390	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AW02_RS19395	COG0438	transferase activity, transferring glycosyl groups
AW02_RS19405	COG0515	serine threonine protein kinase
AW02_RS19415	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AW02_RS19420	COG4241	membrane
AW02_RS19430	COG5577	PFAM Coat F domain
AW02_RS19435	COG1733	regulation of RNA biosynthetic process
AW02_RS19445	COG0697	spore germination
AW02_RS19450	COG1621	beta-fructofuranosidase activity
AW02_RS19455	COG1621	beta-fructofuranosidase activity
AW02_RS19460	COG1802	Transcriptional regulator
AW02_RS19465	COG2318	DinB family
AW02_RS19470	COG2211	Major facilitator Superfamily
AW02_RS19480	COG0778	Nitroreductase
AW02_RS19485	COG1846	Transcriptional regulator
AW02_RS19490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW02_RS19495	COG1846	Transcriptional regulator
AW02_RS19510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW02_RS19515	COG0583	DNA-binding transcription factor activity
AW02_RS19520	COG1028	Short-chain dehydrogenase reductase Sdr
AW02_RS19525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW02_RS19530	COG0697	spore germination
AW02_RS19540	COG1959	2 iron, 2 sulfur cluster binding
AW02_RS19545	COG1396	sequence-specific DNA binding
AW02_RS19555	COG1331	Highly conserved protein containing a thioredoxin domain
AW02_RS19560	COG1266	CAAX protease self-immunity
AW02_RS19565	COG2814	Major facilitator Superfamily
AW02_RS19565	COG0477	Major facilitator Superfamily
AW02_RS19570	COG0346	lactoylglutathione lyase activity
AW02_RS19575	COG1609	Transcriptional regulator
AW02_RS19580	COG0708	Exodeoxyribonuclease III
AW02_RS19585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW02_RS19590	COG2169	Transcriptional regulator
AW02_RS19600	COG0629	single-stranded DNA binding
AW02_RS19610	COG0012	GTP binding
AW02_RS19615	COG0243	molybdopterin cofactor binding
AW02_RS19620	COG4481	Protein conserved in bacteria
AW02_RS19625	COG3949	Membrane
AW02_RS19640	COG1475	DNA binding
AW02_RS19645	COG1192	Involved in chromosome partitioning
AW02_RS19670	COG1847	R3H domain protein
AW02_RS19675	COG0706	membrane insertase activity
AW02_RS19735	COG1793	dna ligase