locus-tag	class	description
GKO36_RS00010	COG0592	DNA-directed DNA polymerase activity
GKO36_RS00015	COG2501	S4 domain
GKO36_RS00030	COG0187	DNA topoisomerase II activity
GKO36_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKO36_RS00070	COG0516	GMP reductase activity
GKO36_RS00070	COG0517	IMP dehydrogenase activity
GKO36_RS00075	COG1686	Belongs to the peptidase S11 family
GKO36_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
GKO36_RS00105	COG1428	Deoxynucleoside kinase
GKO36_RS00110	COG1428	Deoxynucleoside kinase
GKO36_RS00115	COG1388	LysM domain
GKO36_RS00115	COG3858	chitin binding
GKO36_RS00120	COG1335	isochorismatase
GKO36_RS00125	COG0590	tRNA wobble adenosine to inosine editing
GKO36_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKO36_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKO36_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GKO36_RS00195	COG3853	Toxic anion resistance protein (TelA)
GKO36_RS00200	COG1982	Orn Lys Arg decarboxylase major
GKO36_RS00210	COG3870	Protein conserved in bacteria
GKO36_RS00215	COG1728	Protein conserved in bacteria
GKO36_RS00220	COG0470	DNA polymerase III
GKO36_RS00225	COG1774	PSP1 C-terminal conserved region
GKO36_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GKO36_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKO36_RS00250	COG2002	toxin-antitoxin pair type II binding
GKO36_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKO36_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKO36_RS00260	COG0084	hydrolase, TatD family'
GKO36_RS00265	COG3583	domain protein
GKO36_RS00265	COG3584	3D domain protein
GKO36_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKO36_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GKO36_RS00285	COG4466	Protein conserved in bacteria
GKO36_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKO36_RS00305	COG0251	oxidation-reduction process
GKO36_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKO36_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKO36_RS00345	COG2002	toxin-antitoxin pair type II binding
GKO36_RS00350	COG2244	polysaccharide biosynthetic process
GKO36_RS00355	COG3956	TIGRFAM MazG family protein
GKO36_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GKO36_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GKO36_RS00380	COG1098	S1 RNA binding domain
GKO36_RS00395	COG2208	phosphoserine phosphatase activity
GKO36_RS00400	COG2304	oxidoreductase activity
GKO36_RS00405	COG0515	serine threonine protein kinase
GKO36_RS00410	COG0037	tRNA processing
GKO36_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GKO36_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKO36_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GKO36_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GKO36_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GKO36_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
GKO36_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GKO36_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GKO36_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKO36_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GKO36_RS00475	COG1396	sequence-specific DNA binding
GKO36_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKO36_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GKO36_RS00565	COG4463	regulation of RNA biosynthetic process
GKO36_RS00570	COG3880	PFAM UvrB UvrC protein
GKO36_RS00580	COG0542	response to heat
GKO36_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKO36_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GKO36_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
GKO36_RS00615	COG1045	serine acetyltransferase
GKO36_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKO36_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKO36_RS00635	COG3688	RNA-binding protein containing a PIN domain
GKO36_RS00640	COG1595	DNA-templated transcription, initiation
GKO36_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GKO36_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
GKO36_RS00680	COG2813	Specifically methylates the guanine in position
GKO36_RS00695	COG1358	cellular component organization or biogenesis
GKO36_RS00720	COG0596	Alpha beta hydrolase
GKO36_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKO36_RS00830	COG0201	protein transport
GKO36_RS00840	COG0024	Methionine aminopeptidase
GKO36_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GKO36_RS00875	COG1122	ATPase activity
GKO36_RS00880	COG1122	ATPase activity
GKO36_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKO36_RS00905	COG2226	methyltransferase
GKO36_RS00910	COG2318	DinB family
GKO36_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS00925	COG0489	protein tyrosine kinase activity
GKO36_RS00935	COG2194	sulfuric ester hydrolase activity
GKO36_RS00940	COG0726	polysaccharide deacetylase
GKO36_RS01000	COG0738	Major facilitator superfamily
GKO36_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKO36_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
GKO36_RS01025	COG0385	Bile acid
GKO36_RS01030	COG2819	hydrolase of the alpha beta superfamily
GKO36_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKO36_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKO36_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GKO36_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GKO36_RS01050	COG2207	Transcriptional regulator
GKO36_RS01055	COG3876	Protein conserved in bacteria
GKO36_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
GKO36_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GKO36_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKO36_RS01070	COG1263	PTS System
GKO36_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKO36_RS01085	COG1683	Conserved Protein
GKO36_RS01115	COG1595	DNA-templated transcription, initiation
GKO36_RS01120	COG5662	AntiSigma factor
GKO36_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKO36_RS01130	COG4856	YbbR-like protein
GKO36_RS01180	COG1346	cytolysis
GKO36_RS01185	COG1380	Effector of murein hydrolase LrgA
GKO36_RS01190	COG1846	Transcriptional regulator
GKO36_RS01195	COG1113	amino acid transport
GKO36_RS01200	COG1011	Hydrolase
GKO36_RS01205	COG4585	Histidine kinase
GKO36_RS01210	COG2197	response regulator
GKO36_RS01215	COG1131	(ABC) transporter
GKO36_RS01255	COG0531	amino acid
GKO36_RS01260	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GKO36_RS01275	COG0584	glycerophosphoryl diester phosphodiesterase
GKO36_RS01280	COG2271	Major facilitator Superfamily
GKO36_RS01290	COG2368	4-hydroxyphenylacetate
GKO36_RS01300	COG3409	Peptidoglycan-binding domain 1 protein
GKO36_RS01315	COG0371	Dehydrogenase
GKO36_RS01325	COG1183	phosphatidylcholine synthase activity
GKO36_RS01330	COG0586	Pfam SNARE associated Golgi protein
GKO36_RS01335	COG0688	phosphatidylethanolamine metabolic process
GKO36_RS01350	COG1301	dicarboxylic acid transport
GKO36_RS01355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GKO36_RS01360	COG0833	amino acid
GKO36_RS01365	COG2040	homocysteine
GKO36_RS01370	COG1115	amino acid carrier protein
GKO36_RS01375	COG2066	Belongs to the glutaminase family
GKO36_RS01380	COG4191	Histidine kinase
GKO36_RS01385	COG0784	Response regulator, receiver
GKO36_RS01390	COG3173	Aminoglycoside phosphotransferase
GKO36_RS01405	COG3773	Cell wall hydrolase
GKO36_RS01410	COG3540	Alkaline phosphatase
GKO36_RS01415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKO36_RS01420	COG0805	protein transport
GKO36_RS01430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKO36_RS01435	COG0477	Major facilitator Superfamily
GKO36_RS01440	COG1309	transcriptional regulator
GKO36_RS01445	COG0252	asparaginase activity
GKO36_RS01450	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GKO36_RS01455	COG3012	SEC-C Motif Domain Protein
GKO36_RS01455	COG1405	negative regulation of cell septum assembly
GKO36_RS01460	COG0667	Aldo Keto reductase
GKO36_RS01470	COG1595	DNA-templated transcription, initiation
GKO36_RS01475	COG1595	DNA-templated transcription, initiation
GKO36_RS01480	COG1876	peptidase activity
GKO36_RS01485	COG0457	Tetratricopeptide repeat
GKO36_RS01490	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS01495	COG0366	Alpha amylase catalytic
GKO36_RS01500	COG0803	Belongs to the bacterial solute-binding protein 9 family
GKO36_RS01505	COG1121	(ABC) transporter
GKO36_RS01510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GKO36_RS01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKO36_RS01520	COG2310	stress, protein
GKO36_RS01525	COG2310	stress, protein
GKO36_RS01530	COG2310	stress, protein
GKO36_RS01535	COG0861	Integral membrane protein TerC family
GKO36_RS01545	COG3853	Toxic anion resistance protein (TelA)
GKO36_RS01550	COG0477	Major facilitator Superfamily
GKO36_RS01555	COG4175	Glycine betaine
GKO36_RS01555	COG0517	IMP dehydrogenase activity
GKO36_RS01560	COG4176	ABC-type proline glycine betaine transport system permease component
GKO36_RS01565	COG2113	Glycine betaine
GKO36_RS01570	COG1473	amidohydrolase
GKO36_RS01575	COG1288	antiporter activity
GKO36_RS01585	COG0366	Alpha amylase catalytic
GKO36_RS01595	COG2814	Major facilitator Superfamily
GKO36_RS01600	COG1846	Transcriptional regulator
GKO36_RS01605	COG1280	lysine exporter protein (LysE YggA)
GKO36_RS01610	COG3403	YqcI/YcgG family
GKO36_RS01615	COG1113	amino acid transport
GKO36_RS01620	COG3665	Urea carboxylase-associated protein
GKO36_RS01635	COG1660	Displays ATPase and GTPase activities
GKO36_RS01645	COG2271	Major facilitator Superfamily
GKO36_RS01650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GKO36_RS01655	COG3458	cephalosporin-C deacetylase activity
GKO36_RS01660	COG3541	Predicted nucleotidyltransferase
GKO36_RS01665	COG0506	proline dehydrogenase activity
GKO36_RS01670	COG1012	belongs to the aldehyde dehydrogenase family
GKO36_RS01675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKO36_RS01690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GKO36_RS01690	COG1587	Uroporphyrinogen-III synthase
GKO36_RS01695	COG2146	nitrite reductase [NAD(P)H] activity
GKO36_RS01700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GKO36_RS01705	COG0243	molybdopterin cofactor binding
GKO36_RS01710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GKO36_RS01715	COG2223	nitrite transmembrane transporter activity
GKO36_RS01720	COG0523	cobalamin synthesis protein
GKO36_RS01725	COG1063	alcohol dehydrogenase
GKO36_RS01730	COG1714	RDD family
GKO36_RS01740	COG2723	6-phospho-beta-galactosidase activity
GKO36_RS01750	COG3209	COG3209 Rhs family protein
GKO36_RS01755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GKO36_RS01760	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GKO36_RS01765	COG1733	regulation of RNA biosynthetic process
GKO36_RS01770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS01780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS01785	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GKO36_RS01800	COG2364	Membrane
GKO36_RS01805	COG1126	abc transporter atp-binding protein
GKO36_RS01810	COG0765	amino acid transport
GKO36_RS01815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKO36_RS01820	COG0583	DNA-binding transcription factor activity
GKO36_RS01825	COG0163	prenyltransferase activity
GKO36_RS01830	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GKO36_RS01845	COG3104	oligopeptide transport
GKO36_RS01850	COG5434	Belongs to the glycosyl hydrolase 28 family
GKO36_RS01860	COG0697	spore germination
GKO36_RS01870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GKO36_RS01875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKO36_RS01880	COG0456	acetyltransferase
GKO36_RS01885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKO36_RS01890	COG0765	amino acid transport
GKO36_RS01895	COG1126	abc transporter atp-binding protein
GKO36_RS01900	COG1473	amidohydrolase
GKO36_RS01905	COG2079	MmgE PrpD family protein
GKO36_RS01910	COG1136	(ABC) transporter
GKO36_RS01915	COG0577	efflux transmembrane transporter activity
GKO36_RS01920	COG0745	RESPONSE REGULATOR receiver
GKO36_RS01925	COG5002	protein histidine kinase activity
GKO36_RS01925	COG3850	Histidine kinase
GKO36_RS01930	COG0457	Tetratricopeptide repeat
GKO36_RS01945	COG0527	aspartate kinase activity
GKO36_RS01950	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKO36_RS01955	COG4605	iron ion homeostasis
GKO36_RS01960	COG4604	ABC transporter, ATP-binding protein
GKO36_RS01965	COG4607	ABC-type enterochelin transport system periplasmic component
GKO36_RS01970	COG2814	Major facilitator Superfamily
GKO36_RS01975	COG1309	transcriptional regulator
GKO36_RS01980	COG0778	Nitroreductase
GKO36_RS01985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GKO36_RS01990	COG0640	Transcriptional regulator
GKO36_RS01995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKO36_RS02000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKO36_RS02005	COG1012	belongs to the aldehyde dehydrogenase family
GKO36_RS02010	COG4975	Glucose uptake
GKO36_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS02020	COG4549	nuclear export factor GLE1
GKO36_RS02025	COG2372	response to copper ion
GKO36_RS02025	COG1276	copper resistance
GKO36_RS02030	COG1349	DNA-binding transcription factor activity
GKO36_RS02040	COG2213	PTS system mannitol-specific
GKO36_RS02045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKO36_RS02055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GKO36_RS02065	COG0561	phosphatase activity
GKO36_RS02075	COG1914	H( )-stimulated, divalent metal cation uptake system
GKO36_RS02085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GKO36_RS02090	COG1984	allophanate hydrolase subunit 2
GKO36_RS02095	COG1414	Transcriptional regulator
GKO36_RS02100	COG2755	lipolytic protein G-D-S-L family
GKO36_RS02110	COG2329	Antibiotic biosynthesis monooxygenase
GKO36_RS02115	COG0768	penicillin binding
GKO36_RS02120	COG4989	oxidoreductase activity
GKO36_RS02125	COG3711	transcriptional antiterminator
GKO36_RS02130	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS02140	COG1917	Cupin 2, conserved barrel domain protein
GKO36_RS02145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKO36_RS02150	COG3871	stress protein (general stress protein 26)
GKO36_RS02160	COG2814	Major facilitator Superfamily
GKO36_RS02165	COG1522	sequence-specific DNA binding
GKO36_RS02170	COG0551	DNA topoisomerase type I activity
GKO36_RS02170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKO36_RS02175	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GKO36_RS02180	COG3706	GGDEF domain
GKO36_RS02185	COG5298	Protein conserved in bacteria
GKO36_RS02190	COG1215	transferase activity, transferring glycosyl groups
GKO36_RS02200	COG0531	amino acid
GKO36_RS02205	COG0494	nUDIX hydrolase
GKO36_RS02210	COG0028	Belongs to the TPP enzyme family
GKO36_RS02235	COG1914	H( )-stimulated, divalent metal cation uptake system
GKO36_RS02245	COG4876	unkown
GKO36_RS02255	COG2076	Multidrug Resistance protein
GKO36_RS02260	COG2217	Heavy metal translocating P-type atpase
GKO36_RS02265	COG3729	General stress protein
GKO36_RS02270	COG0662	Cupin 2, conserved barrel domain protein
GKO36_RS02275	COG2329	Antibiotic biosynthesis monooxygenase
GKO36_RS02280	COG3546	catalase activity
GKO36_RS02285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GKO36_RS02290	COG3290	protein histidine kinase activity
GKO36_RS02295	COG4565	transcriptional regulatory protein
GKO36_RS02300	COG1301	dicarboxylic acid transport
GKO36_RS02305	COG0628	permease
GKO36_RS02310	COG1131	(ABC) transporter
GKO36_RS02315	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GKO36_RS02325	COG1960	acyl-CoA dehydrogenase activity
GKO36_RS02340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKO36_RS02345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKO36_RS02355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GKO36_RS02360	COG0513	Belongs to the DEAD box helicase family
GKO36_RS02365	COG3402	PFAM membrane-flanked domain
GKO36_RS02370	COG3428	Bacterial PH domain
GKO36_RS02375	COG0705	Rhomboid family
GKO36_RS02385	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GKO36_RS02390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKO36_RS02395	COG0864	Transcriptional regulator
GKO36_RS02400	COG2337	Toxic component of a toxin-antitoxin (TA) module
GKO36_RS02405	COG1366	Belongs to the anti-sigma-factor antagonist family
GKO36_RS02410	COG1366	Belongs to the anti-sigma-factor antagonist family
GKO36_RS02415	COG2172	sigma factor antagonist activity
GKO36_RS02420	COG2208	phosphoserine phosphatase activity
GKO36_RS02425	COG1366	Belongs to the anti-sigma-factor antagonist family
GKO36_RS02435	COG1191	sigma factor activity
GKO36_RS02440	COG2208	phosphoserine phosphatase activity
GKO36_RS02445	COG2183	response to ionizing radiation
GKO36_RS02520	COG0457	Tetratricopeptide repeat
GKO36_RS02530	COG0477	Major facilitator Superfamily
GKO36_RS02540	COG2030	dehydratase
GKO36_RS02555	COG1959	2 iron, 2 sulfur cluster binding
GKO36_RS02560	COG2910	NAD(P)H-binding
GKO36_RS02570	COG1309	transcriptional regulator
GKO36_RS02575	COG3239	Fatty acid desaturase
GKO36_RS02585	COG1278	Cold shock
GKO36_RS02590	COG1329	Transcriptional regulator
GKO36_RS02595	COG1937	Protein conserved in bacteria
GKO36_RS02600	COG2210	Belongs to the sulfur carrier protein TusA family
GKO36_RS02605	COG1054	Belongs to the UPF0176 family
GKO36_RS02610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKO36_RS02610	COG0425	Belongs to the sulfur carrier protein TusA family
GKO36_RS02615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKO36_RS02615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKO36_RS02620	COG0425	Belongs to the sulfur carrier protein TusA family
GKO36_RS02625	COG0730	response to heat
GKO36_RS02630	COG1794	racemase activity, acting on amino acids and derivatives
GKO36_RS02645	COG3621	Patatin-like phospholipase
GKO36_RS02655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GKO36_RS02660	COG1802	Transcriptional regulator
GKO36_RS02665	COG0251	oxidation-reduction process
GKO36_RS02670	COG0814	amino acid
GKO36_RS02675	COG1473	amidohydrolase
GKO36_RS02680	COG2207	Transcriptional regulator
GKO36_RS02680	COG1917	Cupin 2, conserved barrel domain protein
GKO36_RS02690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKO36_RS02695	COG0477	Major facilitator Superfamily
GKO36_RS02715	COG0277	FAD linked oxidase domain protein
GKO36_RS02740	COG2318	DinB family
GKO36_RS02770	COG0351	phosphomethylpyrimidine kinase
GKO36_RS02785	COG1064	alcohol dehydrogenase
GKO36_RS02790	COG0789	Transcriptional regulator
GKO36_RS02800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKO36_RS02815	COG2814	Major facilitator Superfamily
GKO36_RS02820	COG1309	transcriptional regulator
GKO36_RS02825	COG0697	spore germination
GKO36_RS02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKO36_RS02835	COG5577	PFAM Coat F domain
GKO36_RS02845	COG1063	alcohol dehydrogenase
GKO36_RS02850	COG5577	PFAM Coat F domain
GKO36_RS02860	COG0738	Major facilitator superfamily
GKO36_RS02875	COG4585	Histidine kinase
GKO36_RS02880	COG2197	response regulator
GKO36_RS02885	COG2409	Drug exporters of the RND superfamily
GKO36_RS02890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GKO36_RS02895	COG0488	(ABC) transporter
GKO36_RS02900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKO36_RS02905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKO36_RS02915	COG2814	Major facilitator Superfamily
GKO36_RS02920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKO36_RS02930	COG0730	response to heat
GKO36_RS02935	COG0456	acetyltransferase
GKO36_RS02940	COG4978	Transcriptional regulator
GKO36_RS02940	COG0789	Transcriptional regulator
GKO36_RS02945	COG0697	spore germination
GKO36_RS02950	COG1051	belongs to the nudix hydrolase family
GKO36_RS02955	COG2226	methyltransferase
GKO36_RS02960	COG0473	3-isopropylmalate dehydrogenase activity
GKO36_RS02965	COG1802	Transcriptional regulator
GKO36_RS02970	COG1819	glycosyl
GKO36_RS02985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GKO36_RS02995	COG1388	LysM domain
GKO36_RS03000	COG2814	Major facilitator Superfamily
GKO36_RS03005	COG2188	Transcriptional regulator
GKO36_RS03010	COG2186	Transcriptional regulator
GKO36_RS03015	COG2807	transmembrane transport
GKO36_RS03020	COG2076	Multidrug Resistance protein
GKO36_RS03025	COG2076	Multidrug Resistance protein
GKO36_RS03030	COG1309	transcriptional regulator
GKO36_RS03035	COG0531	amino acid
GKO36_RS03045	COG3832	glyoxalase III activity
GKO36_RS03050	COG0604	alcohol dehydrogenase
GKO36_RS03055	COG2814	Major facilitator Superfamily
GKO36_RS03095	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GKO36_RS03100	COG0802	atpase or kinase
GKO36_RS03105	COG1214	PFAM Peptidase M22, glycoprotease
GKO36_RS03110	COG0456	acetyltransferase
GKO36_RS03115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKO36_RS03120	COG0488	(ABC) transporter
GKO36_RS03135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKO36_RS03140	COG0805	protein transport
GKO36_RS03150	COG1266	CAAX protease self-immunity
GKO36_RS03170	COG0457	Tetratricopeptide repeat
GKO36_RS03175	COG1063	alcohol dehydrogenase
GKO36_RS03180	COG2211	Major facilitator Superfamily
GKO36_RS03185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKO36_RS03195	COG1842	Phage shock protein A
GKO36_RS03200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKO36_RS03205	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GKO36_RS03210	COG4260	virion core protein, lumpy skin disease virus
GKO36_RS03215	COG2755	lipolytic protein G-D-S-L family
GKO36_RS03215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GKO36_RS03225	COG1595	DNA-templated transcription, initiation
GKO36_RS03230	COG1063	alcohol dehydrogenase
GKO36_RS03235	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GKO36_RS03240	COG0823	Involved in the tonB-independent uptake of proteins
GKO36_RS03255	COG2132	Multicopper oxidase
GKO36_RS03260	COG1113	amino acid transport
GKO36_RS03265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKO36_RS03270	COG0714	Associated with various cellular activities
GKO36_RS03275	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GKO36_RS03280	COG1305	Transglutaminase-like
GKO36_RS03290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GKO36_RS03310	COG2211	Major facilitator Superfamily
GKO36_RS03325	COG2252	PERMEase
GKO36_RS03330	COG3064	Membrane
GKO36_RS03350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GKO36_RS03355	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GKO36_RS03360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKO36_RS03365	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GKO36_RS03370	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKO36_RS03385	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GKO36_RS03395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GKO36_RS03400	COG0138	bifunctional purine biosynthesis protein purh
GKO36_RS03405	COG0151	Belongs to the GarS family
GKO36_RS03415	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GKO36_RS03420	COG1470	cell adhesion involved in biofilm formation
GKO36_RS03425	COG4496	protein, YerC YecD
GKO36_RS03440	COG0210	DNA helicase
GKO36_RS03450	COG4851	CamS sex pheromone cAM373 precursor
GKO36_RS03455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GKO36_RS03460	COG1285	pathogenesis
GKO36_RS03465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKO36_RS03485	COG1309	transcriptional regulator
GKO36_RS03490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GKO36_RS03495	COG1597	lipid kinase activity
GKO36_RS03500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKO36_RS03505	COG1136	(ABC) transporter
GKO36_RS03515	COG1131	(ABC) transporter
GKO36_RS03590	COG3546	catalase activity
GKO36_RS03595	COG0454	-acetyltransferase
GKO36_RS03605	COG2323	membrane
GKO36_RS03610	COG2329	Antibiotic biosynthesis monooxygenase
GKO36_RS03620	COG1366	Belongs to the anti-sigma-factor antagonist family
GKO36_RS03625	COG5583	Uncharacterized small protein (DUF2292)
GKO36_RS03630	COG0196	riboflavin kinase activity
GKO36_RS03635	COG0670	Belongs to the BI1 family
GKO36_RS03640	COG1846	Transcriptional regulator
GKO36_RS03645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GKO36_RS03655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GKO36_RS03655	COG2124	cytochrome p450
GKO36_RS03670	COG1131	(ABC) transporter
GKO36_RS03680	COG1368	sulfuric ester hydrolase activity
GKO36_RS03685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GKO36_RS03690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKO36_RS03695	COG1442	glycosyl transferase family 8
GKO36_RS03700	COG1216	Glycosyl transferase, family 2
GKO36_RS03705	COG1442	glycosyl transferase family 8
GKO36_RS03710	COG2223	nitrite transmembrane transporter activity
GKO36_RS03715	COG0531	amino acid
GKO36_RS03720	COG1012	belongs to the aldehyde dehydrogenase family
GKO36_RS03725	COG0840	transmembrane signaling receptor activity
GKO36_RS03730	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS03735	COG0463	Glycosyl transferase, family 2
GKO36_RS03735	COG0457	Tetratricopeptide repeat
GKO36_RS03740	COG0488	(ABC) transporter
GKO36_RS03745	COG0789	Transcriptional regulator
GKO36_RS03750	COG2814	Major facilitator Superfamily
GKO36_RS03755	COG0488	(ABC) transporter
GKO36_RS03760	COG0513	Belongs to the DEAD box helicase family
GKO36_RS03770	COG2130	NADP-dependent
GKO36_RS03785	COG3866	Pectate lyase
GKO36_RS03790	COG0471	metal ion transport
GKO36_RS03805	COG0745	RESPONSE REGULATOR receiver
GKO36_RS03805	COG2972	Histidine kinase
GKO36_RS03810	COG3279	Response regulator of the LytR AlgR family
GKO36_RS03820	COG3764	Sortase (surface protein transpeptidase)
GKO36_RS03825	COG3290	protein histidine kinase activity
GKO36_RS03830	COG4565	transcriptional regulatory protein
GKO36_RS03835	COG3181	Tripartite tricarboxylate transporter family receptor
GKO36_RS03840	COG2851	Citrate transporter
GKO36_RS03845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKO36_RS03850	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GKO36_RS03860	COG2258	MOSC domain
GKO36_RS03880	COG0024	Methionine aminopeptidase
GKO36_RS03885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKO36_RS03885	COG1263	PTS System
GKO36_RS03895	COG1368	sulfuric ester hydrolase activity
GKO36_RS03905	COG0071	Belongs to the small heat shock protein (HSP20) family
GKO36_RS03920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKO36_RS03920	COG1263	PTS System
GKO36_RS03925	COG0366	Alpha amylase catalytic
GKO36_RS03930	COG2188	Transcriptional regulator
GKO36_RS03935	COG0778	Nitroreductase
GKO36_RS03950	COG0737	Belongs to the 5'-nucleotidase family
GKO36_RS03955	COG0693	protein deglycase activity
GKO36_RS03960	COG1609	Transcriptional regulator
GKO36_RS03975	COG2814	Major facilitator Superfamily
GKO36_RS03985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKO36_RS03990	COG4980	gas vesicle protein
GKO36_RS03995	COG1295	ribonuclease BN
GKO36_RS04000	COG0477	Major facilitator Superfamily
GKO36_RS04005	COG0387	Pfam Sodium calcium exchanger
GKO36_RS04015	COG0668	transmembrane transport
GKO36_RS04020	COG0535	radical SAM domain protein
GKO36_RS04030	COG0726	polysaccharide deacetylase
GKO36_RS04050	COG0745	RESPONSE REGULATOR receiver
GKO36_RS04055	COG2205	protein histidine kinase activity
GKO36_RS04060	COG2084	Dehydrogenase
GKO36_RS04070	COG0598	Magnesium transport protein CorA
GKO36_RS04075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GKO36_RS04080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKO36_RS04090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKO36_RS04095	COG4637	Psort location Cytoplasmic, score
GKO36_RS04100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GKO36_RS04105	COG0022	dehydrogenase e1 component
GKO36_RS04110	COG0508	dehydrogenase complex catalyzes the overall conversion of
GKO36_RS04115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GKO36_RS04120	COG3284	Transcriptional regulator
GKO36_RS04130	COG1486	melibiose metabolic process
GKO36_RS04135	COG1737	Transcriptional regulator
GKO36_RS04140	COG1263	PTS System
GKO36_RS04140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKO36_RS04145	COG1132	(ABC) transporter
GKO36_RS04150	COG1132	(ABC) transporter
GKO36_RS04155	COG2259	Doxx family
GKO36_RS04160	COG2514	catechol 2,3-dioxygenase activity
GKO36_RS04170	COG1695	Transcriptional regulator
GKO36_RS04175	COG2249	NAD(P)H dehydrogenase (quinone) activity
GKO36_RS04180	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GKO36_RS04185	COG0574	Belongs to the PEP-utilizing enzyme family
GKO36_RS04185	COG3848	Pyruvate phosphate dikinase
GKO36_RS04190	COG2732	(Barnase) inhibitor
GKO36_RS04195	COG2318	DinB family
GKO36_RS04200	COG2814	Major facilitator Superfamily
GKO36_RS04205	COG1846	Transcriptional regulator
GKO36_RS04210	COG0392	lysyltransferase activity
GKO36_RS04210	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKO36_RS04215	COG0384	phenazine biosynthesis protein PhzF
GKO36_RS04220	COG0778	Nitroreductase
GKO36_RS04235	COG1090	epimerase
GKO36_RS04250	COG2814	Major facilitator Superfamily
GKO36_RS04260	COG3591	Belongs to the peptidase S1B family
GKO36_RS04275	COG3103	Sh3 type 3 domain protein
GKO36_RS04280	COG5658	integral membrane protein
GKO36_RS04285	COG0596	Alpha beta hydrolase
GKO36_RS04290	COG0463	Glycosyl transferase, family 2
GKO36_RS04295	COG4485	Bacterial membrane protein, YfhO
GKO36_RS04300	COG1988	membrane-bound metal-dependent
GKO36_RS04305	COG1194	a g-specific adenine glycosylase
GKO36_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS04335	COG1132	(ABC) transporter
GKO36_RS04340	COG4129	membrane
GKO36_RS04350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GKO36_RS04355	COG0735	belongs to the Fur family
GKO36_RS04465	COG1757	Na H antiporter
GKO36_RS04470	COG3340	Belongs to the peptidase S51 family
GKO36_RS04480	COG0277	FAD linked oxidase domain protein
GKO36_RS04490	COG0747	negative chemotaxis
GKO36_RS04495	COG0601	transmembrane transport
GKO36_RS04500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKO36_RS04505	COG0444	Belongs to the ABC transporter superfamily
GKO36_RS04510	COG4608	Belongs to the ABC transporter superfamily
GKO36_RS04515	COG0753	catalase activity
GKO36_RS04525	COG1116	anion transmembrane transporter activity
GKO36_RS04530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GKO36_RS04535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GKO36_RS04555	COG1476	TRANSCRIPTIONal
GKO36_RS04565	COG3382	B3 4 domain protein
GKO36_RS04570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GKO36_RS04580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GKO36_RS04585	COG0789	Transcriptional regulator
GKO36_RS04590	COG1664	Polymer-forming cytoskeletal
GKO36_RS04595	COG1664	Polymer-forming cytoskeletal
GKO36_RS04600	COG2766	serine protein kinase
GKO36_RS04610	COG1846	Transcriptional regulator
GKO36_RS04615	COG1566	PFAM secretion protein HlyD family protein
GKO36_RS04620	COG2814	Major facilitator Superfamily
GKO36_RS04625	COG0655	NAD(P)H dehydrogenase (quinone) activity
GKO36_RS04640	COG1725	Transcriptional regulator
GKO36_RS04645	COG1131	(ABC) transporter
GKO36_RS04650	COG1131	(ABC) transporter
GKO36_RS04655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GKO36_RS04660	COG1278	Cold shock
GKO36_RS04665	COG1464	Belongs to the NlpA lipoprotein family
GKO36_RS04670	COG3706	GGDEF domain
GKO36_RS04675	COG1823	symporter activity
GKO36_RS04695	COG5577	PFAM Coat F domain
GKO36_RS04700	COG0737	Belongs to the 5'-nucleotidase family
GKO36_RS04700	COG1525	nuclease
GKO36_RS04700	COG4085	toxin activity
GKO36_RS04705	COG3764	Sortase (surface protein transpeptidase)
GKO36_RS04710	COG0564	pseudouridine synthase activity
GKO36_RS04720	COG0517	IMP dehydrogenase activity
GKO36_RS04725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GKO36_RS04730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GKO36_RS04730	COG3153	acetyltransferase
GKO36_RS04735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GKO36_RS04740	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GKO36_RS04745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GKO36_RS04755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GKO36_RS04760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKO36_RS04765	COG4585	Histidine kinase
GKO36_RS04765	COG2203	Gaf domain
GKO36_RS04770	COG2197	response regulator
GKO36_RS04775	COG0431	NADPH-dependent FMN reductase
GKO36_RS04790	COG0791	NLP P60 protein
GKO36_RS04790	COG1388	LysM domain
GKO36_RS04795	COG1959	2 iron, 2 sulfur cluster binding
GKO36_RS04800	COG0668	transmembrane transport
GKO36_RS04805	COG2719	SpoVR family
GKO36_RS04810	COG1785	Belongs to the alkaline phosphatase family
GKO36_RS04815	COG1388	LysM domain
GKO36_RS04815	COG0791	NLP P60 protein
GKO36_RS04820	COG0583	DNA-binding transcription factor activity
GKO36_RS04825	COG0372	Belongs to the citrate synthase family
GKO36_RS04830	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS04835	COG0531	amino acid
GKO36_RS04840	COG0733	neurotransmitter:sodium symporter activity
GKO36_RS04855	COG1595	DNA-templated transcription, initiation
GKO36_RS04860	COG0204	Acyl-transferase
GKO36_RS04865	COG1253	flavin adenine dinucleotide binding
GKO36_RS04870	COG0789	Transcriptional regulator
GKO36_RS04875	COG0436	Aminotransferase
GKO36_RS04880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKO36_RS04885	COG1253	flavin adenine dinucleotide binding
GKO36_RS04890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKO36_RS04895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKO36_RS04900	COG0584	glycerophosphoryl diester phosphodiesterase
GKO36_RS04910	COG0668	transmembrane transport
GKO36_RS04915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GKO36_RS04920	COG0726	polysaccharide deacetylase
GKO36_RS04925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GKO36_RS04930	COG3226	Transcriptional regulator
GKO36_RS04940	COG0589	response to stress
GKO36_RS04945	COG1132	(ABC) transporter
GKO36_RS04950	COG1132	(ABC) transporter
GKO36_RS04955	COG0702	epimerase
GKO36_RS04970	COG0189	ligase activity
GKO36_RS04975	COG0189	ligase activity
GKO36_RS04990	COG4335	DNA alkylation repair
GKO36_RS04995	COG0561	phosphatase activity
GKO36_RS05000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GKO36_RS05010	COG0475	glutathione-regulated potassium exporter activity
GKO36_RS05015	COG0490	domain, Protein
GKO36_RS05025	COG1024	Enoyl-CoA hydratase
GKO36_RS05035	COG4152	abc transporter atp-binding protein
GKO36_RS05040	COG1668	transmembrane transport
GKO36_RS05045	COG0420	3'-5' exonuclease activity
GKO36_RS05050	COG4717	serine-type aminopeptidase activity
GKO36_RS05065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GKO36_RS05100	COG4980	gas vesicle protein
GKO36_RS05115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GKO36_RS05120	COG0537	adenosine 5'-monophosphoramidase activity
GKO36_RS05125	COG1131	(ABC) transporter
GKO36_RS05130	COG4473	ABC transporter
GKO36_RS05140	COG1473	amidohydrolase
GKO36_RS05145	COG3069	C4-dicarboxylate transmembrane transporter activity
GKO36_RS05150	COG2329	Antibiotic biosynthesis monooxygenase
GKO36_RS05155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GKO36_RS05165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GKO36_RS05170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GKO36_RS05175	COG1309	transcriptional regulator
GKO36_RS05180	COG1511	domain protein
GKO36_RS05185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKO36_RS05195	COG1363	Peptidase, m42
GKO36_RS05200	COG1301	dicarboxylic acid transport
GKO36_RS05210	COG1234	tRNA 3'-trailer cleavage
GKO36_RS05215	COG0095	Lipoate-protein ligase
GKO36_RS05220	COG0702	epimerase
GKO36_RS05225	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS05235	COG0501	Belongs to the peptidase M48B family
GKO36_RS05240	COG1404	Belongs to the peptidase S8 family
GKO36_RS05245	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GKO36_RS05250	COG0406	alpha-ribazole phosphatase activity
GKO36_RS05255	COG0183	Belongs to the thiolase family
GKO36_RS05260	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS05265	COG1268	BioY protein
GKO36_RS05270	COG0840	transmembrane signaling receptor activity
GKO36_RS05275	COG0723	plastoquinol--plastocyanin reductase activity
GKO36_RS05275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKO36_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS05290	COG4903	ComK protein
GKO36_RS05295	COG5646	InterPro IPR014922
GKO36_RS05320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKO36_RS05335	COG0398	Pfam SNARE associated Golgi protein
GKO36_RS05340	COG0681	Belongs to the peptidase S26 family
GKO36_RS05345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GKO36_RS05350	COG1846	Transcriptional regulator
GKO36_RS05355	COG3180	Ammonia monooxygenase
GKO36_RS05360	COG2814	Major facilitator Superfamily
GKO36_RS05370	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GKO36_RS05375	COG2323	membrane
GKO36_RS05390	COG0420	3'-5' exonuclease activity
GKO36_RS05395	COG0419	ATPase involved in DNA repair
GKO36_RS05400	COG1403	HNH endonuclease
GKO36_RS05440	COG0179	Fumarylacetoacetate (FAA) hydrolase
GKO36_RS05460	COG0367	asparagine synthase
GKO36_RS05465	COG1562	ergosterol biosynthetic process
GKO36_RS05470	COG0534	Mate efflux family protein
GKO36_RS05475	COG1917	Cupin 2, conserved barrel domain protein
GKO36_RS05475	COG2207	Transcriptional regulator
GKO36_RS05480	COG1609	Transcriptional regulator
GKO36_RS05485	COG0673	inositol 2-dehydrogenase activity
GKO36_RS05490	COG2318	DinB family
GKO36_RS05495	COG1279	arginine transmembrane transporter activity
GKO36_RS05500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKO36_RS05505	COG1357	PFAM Pentapeptide repeats (8 copies)
GKO36_RS05510	COG2153	protein acetylation
GKO36_RS05515	COG0646	methionine synthase
GKO36_RS05515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GKO36_RS05525	COG2996	Protein conserved in bacteria
GKO36_RS05530	COG1744	ABC transporter substrate-binding protein PnrA-like
GKO36_RS05535	COG0840	transmembrane signaling receptor activity
GKO36_RS05540	COG2124	cytochrome p450
GKO36_RS05550	COG1307	EDD domain protein, DegV family
GKO36_RS05555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKO36_RS05575	COG0561	phosphatase activity
GKO36_RS05580	COG1073	alpha beta
GKO36_RS05585	COG2151	metal-sulfur cluster biosynthetic enzyme
GKO36_RS05595	COG0277	FAD linked oxidase domain protein
GKO36_RS05600	COG2271	Major facilitator Superfamily
GKO36_RS05610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GKO36_RS05620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GKO36_RS05625	COG0505	Belongs to the CarA family
GKO36_RS05630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GKO36_RS05635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKO36_RS05650	COG2267	carboxylic ester hydrolase activity
GKO36_RS05660	COG1744	ABC transporter substrate-binding protein PnrA-like
GKO36_RS05675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKO36_RS05680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKO36_RS05685	COG5504	Zn-dependent protease
GKO36_RS05690	COG0444	Belongs to the ABC transporter superfamily
GKO36_RS05695	COG4608	Belongs to the ABC transporter superfamily
GKO36_RS05705	COG0601	transmembrane transport
GKO36_RS05710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKO36_RS05720	COG0180	Tryptophanyl-tRNA synthetase
GKO36_RS05725	COG4166	transmembrane transport
GKO36_RS05730	COG0601	transmembrane transport
GKO36_RS05735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKO36_RS05740	COG0444	Belongs to the ABC transporter superfamily
GKO36_RS05745	COG4608	Belongs to the ABC transporter superfamily
GKO36_RS05755	COG0456	acetyltransferase
GKO36_RS05760	COG1393	Belongs to the ArsC family
GKO36_RS05765	COG0861	Integral membrane protein TerC family
GKO36_RS05770	COG4862	establishment of competence for transformation
GKO36_RS05775	COG4469	Competence protein
GKO36_RS05780	COG1164	Oligoendopeptidase f
GKO36_RS05790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GKO36_RS05795	COG2346	COG2346, Truncated hemoglobins
GKO36_RS05800	COG0741	lytic transglycosylase activity
GKO36_RS05805	COG4116	CYTH
GKO36_RS05815	COG2357	RelA SpoT domain protein
GKO36_RS05820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKO36_RS05825	COG0564	pseudouridine synthase activity
GKO36_RS05835	COG0569	domain protein
GKO36_RS05835	COG0475	glutathione-regulated potassium exporter activity
GKO36_RS05840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GKO36_RS05845	COG0352	thiamine-phosphate diphosphorylase activity
GKO36_RS05850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKO36_RS05855	COG2104	thiamine diphosphate biosynthetic process
GKO36_RS05865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GKO36_RS05870	COG0351	phosphomethylpyrimidine kinase
GKO36_RS05875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GKO36_RS05930	COG0210	DNA helicase
GKO36_RS05950	COG1131	(ABC) transporter
GKO36_RS05960	COG2153	protein acetylation
GKO36_RS05970	COG2382	esterase
GKO36_RS05975	COG0626	cystathionine gamma-synthase activity
GKO36_RS05980	COG0626	cystathionine gamma-synthase activity
GKO36_RS06010	COG5444	nuclease activity
GKO36_RS06025	COG0135	phosphoribosylanthranilate isomerase activity
GKO36_RS06035	COG0346	lactoylglutathione lyase activity
GKO36_RS06040	COG2367	Beta-lactamase
GKO36_RS06045	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GKO36_RS06050	COG0477	Major facilitator Superfamily
GKO36_RS06055	COG1846	Transcriptional regulator
GKO36_RS06065	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GKO36_RS06070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKO36_RS06075	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKO36_RS06080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKO36_RS06080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKO36_RS06085	COG1447	Phosphotransferase system cellobiose-specific component IIA
GKO36_RS06115	COG1285	pathogenesis
GKO36_RS06130	COG2205	protein histidine kinase activity
GKO36_RS06140	COG3383	formate dehydrogenase (NAD+) activity
GKO36_RS06145	COG2427	Protein of unknown function (DUF1641)
GKO36_RS06150	COG2124	cytochrome p450
GKO36_RS06155	COG1819	glycosyl
GKO36_RS06165	COG1587	Uroporphyrinogen-III synthase
GKO36_RS06170	COG0390	transport system, permease component
GKO36_RS06175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GKO36_RS06180	COG0697	spore germination
GKO36_RS06185	COG4297	protein containing double-stranded beta helix domain
GKO36_RS06195	COG1252	NADH dehydrogenase
GKO36_RS06205	COG2211	Major facilitator Superfamily
GKO36_RS06210	COG1609	Transcriptional regulator
GKO36_RS06215	COG0246	Mannitol dehydrogenase
GKO36_RS06220	COG2721	sulfolactate sulfo-lyase activity
GKO36_RS06225	COG0730	response to heat
GKO36_RS06230	COG2318	DinB family
GKO36_RS06235	COG0457	Tetratricopeptide repeat
GKO36_RS06245	COG5632	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS06245	COG1388	LysM domain
GKO36_RS06245	COG3409	Peptidoglycan-binding domain 1 protein
GKO36_RS06255	COG4195	phage-related replication protein
GKO36_RS06265	COG2856	Zn peptidase
GKO36_RS06270	COG1396	sequence-specific DNA binding
GKO36_RS06280	COG1522	sequence-specific DNA binding
GKO36_RS06285	COG1484	DNA-dependent DNA replication
GKO36_RS06305	COG1595	DNA-templated transcription, initiation
GKO36_RS06310	COG4193	domain, Protein
GKO36_RS06345	COG5632	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS06345	COG3409	Peptidoglycan-binding domain 1 protein
GKO36_RS06360	COG0306	phosphate transporter
GKO36_RS06365	COG1392	Phosphate transport regulator
GKO36_RS06370	COG0531	amino acid
GKO36_RS06375	COG0346	lactoylglutathione lyase activity
GKO36_RS06380	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKO36_RS06385	COG0463	Glycosyl transferase, family 2
GKO36_RS06395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKO36_RS06400	COG0477	Major facilitator Superfamily
GKO36_RS06405	COG2362	D-Aminopeptidase
GKO36_RS06410	COG0601	transmembrane transport
GKO36_RS06415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKO36_RS06420	COG0444	Belongs to the ABC transporter superfamily
GKO36_RS06425	COG4166	transmembrane transport
GKO36_RS06430	COG1619	proteins homologs of microcin C7 resistance protein MccF
GKO36_RS06435	COG4948	Mandelate Racemase Muconate Lactonizing
GKO36_RS06440	COG0791	NLP P60 protein
GKO36_RS06445	COG4608	Belongs to the ABC transporter superfamily
GKO36_RS06450	COG2706	6-phosphogluconolactonase activity
GKO36_RS06455	COG1834	amidinotransferase
GKO36_RS06460	COG1607	acyl-coa hydrolase
GKO36_RS06465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKO36_RS06470	COG2076	Multidrug Resistance protein
GKO36_RS06475	COG2076	Multidrug Resistance protein
GKO36_RS06480	COG0788	formyltetrahydrofolate deformylase activity
GKO36_RS06485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKO36_RS06495	COG1764	response to oxidative stress
GKO36_RS06500	COG1846	Transcriptional regulator
GKO36_RS06505	COG1764	response to oxidative stress
GKO36_RS06520	COG0457	Tetratricopeptide repeat
GKO36_RS06520	COG0463	Glycosyl transferase, family 2
GKO36_RS06530	COG2814	Major facilitator Superfamily
GKO36_RS06535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GKO36_RS06545	COG1404	Belongs to the peptidase S8 family
GKO36_RS06550	COG1366	Belongs to the anti-sigma-factor antagonist family
GKO36_RS06555	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKO36_RS06560	COG1122	ATPase activity
GKO36_RS06565	COG4721	ABC-type cobalt transport system, permease component
GKO36_RS06570	COG3858	chitin binding
GKO36_RS06570	COG1388	LysM domain
GKO36_RS06580	COG2239	Acts as a magnesium transporter
GKO36_RS06585	COG0789	Transcriptional regulator
GKO36_RS06600	COG1846	Transcriptional regulator
GKO36_RS06605	COG0726	polysaccharide deacetylase
GKO36_RS06610	COG1793	dna ligase
GKO36_RS06610	COG3285	dna ligase
GKO36_RS06615	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GKO36_RS06625	COG0586	Pfam SNARE associated Golgi protein
GKO36_RS06630	COG0861	Integral membrane protein TerC family
GKO36_RS06635	COG1191	sigma factor activity
GKO36_RS06660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GKO36_RS06665	COG2323	membrane
GKO36_RS06675	COG3594	Acyltransferase
GKO36_RS06680	COG5002	protein histidine kinase activity
GKO36_RS06685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKO36_RS06700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GKO36_RS06705	COG0436	Aminotransferase
GKO36_RS06735	COG3852	Histidine kinase
GKO36_RS06740	COG1846	Transcriptional regulator
GKO36_RS06745	COG1360	Flagellar Motor Protein
GKO36_RS06750	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GKO36_RS06755	COG0542	response to heat
GKO36_RS06760	COG3949	Membrane
GKO36_RS06775	COG0720	synthase
GKO36_RS06780	COG0602	queuosine metabolic process
GKO36_RS06790	COG1733	regulation of RNA biosynthetic process
GKO36_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS06810	COG4873	Protein conserved in bacteria
GKO36_RS06820	COG3773	Cell wall hydrolase
GKO36_RS06825	COG2244	polysaccharide biosynthetic process
GKO36_RS06830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKO36_RS06835	COG2217	Heavy metal translocating P-type atpase
GKO36_RS06840	COG0006	proline dipeptidase activity
GKO36_RS06845	COG1609	Transcriptional regulator
GKO36_RS06850	COG3711	transcriptional antiterminator
GKO36_RS06855	COG1263	PTS System
GKO36_RS06855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKO36_RS06855	COG2190	(PTS) system
GKO36_RS06860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKO36_RS06865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKO36_RS06875	COG1533	DNA photolyase activity
GKO36_RS06880	COG0840	transmembrane signaling receptor activity
GKO36_RS06885	COG2084	Dehydrogenase
GKO36_RS06895	COG2340	Cysteine-rich secretory protein family
GKO36_RS06900	COG0768	penicillin binding
GKO36_RS06905	COG4191	Histidine kinase
GKO36_RS06910	COG0436	Aminotransferase
GKO36_RS06920	COG0784	Response regulator, receiver
GKO36_RS06920	COG0835	chemotaxis
GKO36_RS06930	COG2814	Major facilitator Superfamily
GKO36_RS06935	COG1376	ErfK ybiS ycfS ynhG family protein
GKO36_RS06940	COG1408	metallophosphoesterase
GKO36_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS06955	COG2200	EAL domain
GKO36_RS06960	COG4703	Protein of unknown function (DUF1797)
GKO36_RS06965	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GKO36_RS06975	COG0517	IMP dehydrogenase activity
GKO36_RS06980	COG0583	DNA-binding transcription factor activity
GKO36_RS06985	COG0716	FMN binding
GKO36_RS06995	COG0716	FMN binding
GKO36_RS07015	COG0668	transmembrane transport
GKO36_RS07020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKO36_RS07040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GKO36_RS07045	COG0303	'Molybdopterin
GKO36_RS07050	COG1763	Mo-molybdopterin cofactor biosynthetic process
GKO36_RS07055	COG0314	molybdopterin synthase activity
GKO36_RS07060	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GKO36_RS07070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKO36_RS07075	COG1136	(ABC) transporter
GKO36_RS07080	COG0577	efflux transmembrane transporter activity
GKO36_RS07085	COG1349	DNA-binding transcription factor activity
GKO36_RS07090	COG1105	Belongs to the carbohydrate kinase PfkB family
GKO36_RS07095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKO36_RS07095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKO36_RS07095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKO36_RS07100	COG0681	Belongs to the peptidase S26 family
GKO36_RS07110	COG0488	(ABC) transporter
GKO36_RS07115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKO36_RS07120	COG2309	aminopeptidase activity
GKO36_RS07130	COG1077	Cell shape determining protein MreB Mrl
GKO36_RS07135	COG2002	toxin-antitoxin pair type II binding
GKO36_RS07140	COG3852	Histidine kinase
GKO36_RS07145	COG2105	PFAM AIG2 family protein
GKO36_RS07145	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GKO36_RS07150	COG0569	domain protein
GKO36_RS07160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKO36_RS07170	COG0561	phosphatase activity
GKO36_RS07175	COG0242	peptide deformylase activity
GKO36_RS07185	COG0497	DNA recombination
GKO36_RS07195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS07195	COG3321	synthase
GKO36_RS07195	COG4221	oxidoreductase activity
GKO36_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS07200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS07200	COG3321	synthase
GKO36_RS07200	COG0300	oxidoreductase activity
GKO36_RS07200	COG4221	oxidoreductase activity
GKO36_RS07205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS07205	COG4221	oxidoreductase activity
GKO36_RS07205	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS07205	COG3321	synthase
GKO36_RS07210	COG0300	oxidoreductase activity
GKO36_RS07210	COG3321	synthase
GKO36_RS07210	COG4221	oxidoreductase activity
GKO36_RS07210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS07215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS07215	COG0300	oxidoreductase activity
GKO36_RS07215	COG3321	synthase
GKO36_RS07215	COG4221	oxidoreductase activity
GKO36_RS07220	COG4221	oxidoreductase activity
GKO36_RS07220	COG3321	synthase
GKO36_RS07220	COG0300	oxidoreductase activity
GKO36_RS07220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS07225	COG3321	synthase
GKO36_RS07225	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS07225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS07225	COG4221	oxidoreductase activity
GKO36_RS07230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GKO36_RS07235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GKO36_RS07240	COG0022	dehydrogenase e1 component
GKO36_RS07245	COG0508	dehydrogenase complex catalyzes the overall conversion of
GKO36_RS07250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GKO36_RS07255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKO36_RS07270	COG1982	Orn Lys Arg decarboxylase major
GKO36_RS07290	COG0483	inositol monophosphate 1-phosphatase activity
GKO36_RS07300	COG3227	Zinc metalloprotease (Elastase)
GKO36_RS07325	COG1217	gtp-binding protein TYPA
GKO36_RS07335	COG4896	Protein conserved in bacteria
GKO36_RS07345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GKO36_RS07350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GKO36_RS07440	COG0457	Tetratricopeptide repeat
GKO36_RS07455	COG2433	Pfam Transposase IS66
GKO36_RS07590	COG0772	Belongs to the SEDS family
GKO36_RS07595	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GKO36_RS07610	COG2010	Cytochrome c
GKO36_RS07610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GKO36_RS07615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GKO36_RS07620	COG1845	cytochrome c oxidase, subunit III
GKO36_RS07625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GKO36_RS07630	COG3336	cytochrome c oxidase
GKO36_RS07640	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GKO36_RS07645	COG2340	Cysteine-rich secretory protein family
GKO36_RS07660	COG3679	Belongs to the UPF0342 family
GKO36_RS07670	COG0742	ribosomal rna small subunit methyltransferase
GKO36_RS07680	COG3314	Sporulation integral membrane protein YlbJ
GKO36_RS07685	COG1752	Esterase of the alpha-beta hydrolase superfamily
GKO36_RS07690	COG3480	Lon protease (S16) C-terminal proteolytic domain
GKO36_RS07700	COG1399	metal-binding, possibly nucleic acid-binding protein
GKO36_RS07720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKO36_RS07740	COG4839	cell division protein FtsL
GKO36_RS07745	COG0768	penicillin binding
GKO36_RS07750	COG0768	penicillin binding
GKO36_RS07770	COG0772	Belongs to the SEDS family
GKO36_RS07785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GKO36_RS07790	COG0849	cell division
GKO36_RS07795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKO36_RS07800	COG1404	Belongs to the peptidase S8 family
GKO36_RS07800	COG4412	M6 family metalloprotease domain protein
GKO36_RS07810	COG1191	sigma factor activity
GKO36_RS07815	COG1191	sigma factor activity
GKO36_RS07820	COG1119	ATPase activity
GKO36_RS07825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GKO36_RS07830	COG1873	PFAM PRC-barrel domain
GKO36_RS07835	COG1496	oxidoreductase activity
GKO36_RS07840	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GKO36_RS07850	COG0762	integral membrane protein
GKO36_RS07855	COG2302	S4 RNA-binding domain
GKO36_RS07860	COG3599	regulation of cell shape
GKO36_RS07865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKO36_RS07870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GKO36_RS07880	COG0564	pseudouridine synthase activity
GKO36_RS07890	COG2233	PERMEase
GKO36_RS07900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GKO36_RS07905	COG0505	Belongs to the CarA family
GKO36_RS07910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GKO36_RS07925	COG0284	orotidine-5'-phosphate decarboxylase activity
GKO36_RS07930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKO36_RS07940	COG0306	phosphate transporter
GKO36_RS07955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GKO36_RS07960	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GKO36_RS07965	COG1648	precorrin-2 dehydrogenase activity
GKO36_RS07980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GKO36_RS07985	COG1561	YicC-like family, N-terminal region
GKO36_RS07995	COG0194	GDP metabolic process
GKO36_RS08005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKO36_RS08010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKO36_RS08015	COG0242	peptide deformylase activity
GKO36_RS08025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKO36_RS08025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKO36_RS08035	COG0631	protein serine/threonine phosphatase activity
GKO36_RS08040	COG0515	serine threonine protein kinase
GKO36_RS08040	COG2815	serine threonine protein kinase
GKO36_RS08050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GKO36_RS08055	COG1564	THIamine pyrophosphokinase
GKO36_RS08070	COG1302	Protein conserved in bacteria
GKO36_RS08075	COG1461	Dihydroxyacetone kinase
GKO36_RS08080	COG1760	l-serine dehydratase
GKO36_RS08085	COG1760	l-serine dehydratase
GKO36_RS08090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKO36_RS08105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GKO36_RS08110	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS08125	COG1196	nuclear chromosome segregation
GKO36_RS08130	COG0552	protein localization to endoplasmic reticulum
GKO36_RS08145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKO36_RS08155	COG1837	Belongs to the UPF0109 family
GKO36_RS08180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKO36_RS08195	COG2257	FlhB HrpN YscU SpaS Family
GKO36_RS08205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GKO36_RS08210	COG0758	DNA mediated transformation
GKO36_RS08215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKO36_RS08225	COG4974	Belongs to the 'phage' integrase family
GKO36_RS08245	COG1815	bacterial-type flagellum-dependent cell motility
GKO36_RS08250	COG1558	bacterial-type flagellum-dependent cell motility
GKO36_RS08255	COG1677	Flagellar hook-basal body complex protein FliE
GKO36_RS08260	COG1766	The M ring may be actively involved in energy transduction
GKO36_RS08265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GKO36_RS08270	COG1317	bacterial-type flagellum organization
GKO36_RS08275	COG1157	protein secretion by the type III secretion system
GKO36_RS08280	COG2882	bacterial-type flagellum organization
GKO36_RS08285	COG3334	PFAM MgtE intracellular
GKO36_RS08290	COG3144	bacterial-type flagellum assembly
GKO36_RS08295	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GKO36_RS08300	COG4786	Flagellar basal body rod
GKO36_RS08305	COG1582	Flagellar protein (FlbD)
GKO36_RS08310	COG1580	Controls the rotational direction of flagella during chemotaxis
GKO36_RS08315	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GKO36_RS08320	COG1776	CheC inhibitor of MCP methylation
GKO36_RS08320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GKO36_RS08325	COG2201	protein-glutamate methylesterase activity
GKO36_RS08330	COG3190	flagellar
GKO36_RS08335	COG1338	Plays a role in the flagellum-specific transport system
GKO36_RS08340	COG1987	bacterial-type flagellum assembly
GKO36_RS08345	COG1684	flagellar biosynthetic protein fliR
GKO36_RS08350	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GKO36_RS08355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GKO36_RS08360	COG1419	protein localization to endoplasmic reticulum
GKO36_RS08365	COG0455	bacterial-type flagellum organization
GKO36_RS08370	COG2201	protein-glutamate methylesterase activity
GKO36_RS08375	COG0643	Histidine kinase
GKO36_RS08375	COG2198	Histidine kinase
GKO36_RS08380	COG0835	chemotaxis
GKO36_RS08385	COG1776	CheC inhibitor of MCP methylation
GKO36_RS08395	COG1191	sigma factor activity
GKO36_RS08425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKO36_RS08430	COG4589	Belongs to the CDS family
GKO36_RS08440	COG0750	zinc metalloprotease
GKO36_RS08450	COG2176	DNA-directed DNA polymerase activity
GKO36_RS08460	COG0195	Participates in both transcription termination and antitermination
GKO36_RS08465	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GKO36_RS08470	COG1358	cellular component organization or biogenesis
GKO36_RS08480	COG1550	Protein conserved in bacteria
GKO36_RS08495	COG0196	riboflavin kinase activity
GKO36_RS08510	COG0726	polysaccharide deacetylase
GKO36_RS08515	COG0612	Peptidase, M16
GKO36_RS08520	COG1873	PFAM PRC-barrel domain
GKO36_RS08525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKO36_RS08530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKO36_RS08535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKO36_RS08540	COG0527	aspartate kinase activity
GKO36_RS08550	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKO36_RS08555	COG0740	serine-type endopeptidase activity
GKO36_RS08565	COG4980	gas vesicle protein
GKO36_RS08565	COG1674	ftsk spoiiie
GKO36_RS08570	COG2188	Transcriptional regulator
GKO36_RS08575	COG2814	Major facilitator Superfamily
GKO36_RS08580	COG1846	Transcriptional regulator
GKO36_RS08585	COG1033	growth of symbiont in host cell
GKO36_RS08585	COG2409	Drug exporters of the RND superfamily
GKO36_RS08590	COG0612	Peptidase, M16
GKO36_RS08595	COG0612	Peptidase, M16
GKO36_RS08600	COG0300	oxidoreductase activity
GKO36_RS08615	COG1426	Protein conserved in bacteria
GKO36_RS08620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKO36_RS08635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GKO36_RS08645	COG1692	metallophosphoesterase
GKO36_RS08650	COG2359	stage V sporulation protein S
GKO36_RS08670	COG4550	Control of competence regulator ComK, YlbF/YmcA
GKO36_RS08740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS08745	COG3425	synthase
GKO36_RS08750	COG1024	Enoyl-CoA hydratase
GKO36_RS08755	COG1024	Enoyl-CoA hydratase
GKO36_RS08760	COG0300	oxidoreductase activity
GKO36_RS08760	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS08760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS08760	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS08760	COG3321	synthase
GKO36_RS08765	COG3321	synthase
GKO36_RS08765	COG0300	oxidoreductase activity
GKO36_RS08765	COG4221	oxidoreductase activity
GKO36_RS08765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS08770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS08770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKO36_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS08770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS08770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS08770	COG3321	synthase
GKO36_RS08770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS08770	COG3321	synthase
GKO36_RS08770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKO36_RS08775	COG4221	oxidoreductase activity
GKO36_RS08775	COG3321	synthase
GKO36_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS08775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS08780	COG3321	synthase
GKO36_RS08780	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GKO36_RS08780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GKO36_RS08780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS08785	COG2124	cytochrome p450
GKO36_RS08795	COG3619	membrane
GKO36_RS08805	COG1404	Belongs to the peptidase S8 family
GKO36_RS08815	COG4195	phage-related replication protein
GKO36_RS08820	COG1764	response to oxidative stress
GKO36_RS08830	COG2076	Multidrug Resistance protein
GKO36_RS08870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKO36_RS08875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKO36_RS08880	COG4112	unkown
GKO36_RS08885	COG0860	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS08890	COG0464	growth
GKO36_RS08895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKO36_RS08900	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GKO36_RS08905	COG0789	Transcriptional regulator
GKO36_RS08910	COG0174	glutamine synthetase
GKO36_RS08915	COG0582	viral genome integration into host DNA
GKO36_RS08925	COG1525	nuclease
GKO36_RS08930	COG5444	nuclease activity
GKO36_RS08965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKO36_RS08970	COG0457	Tetratricopeptide repeat
GKO36_RS08990	COG5632	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS08990	COG3409	Peptidoglycan-binding domain 1 protein
GKO36_RS08995	COG5434	Belongs to the glycosyl hydrolase 28 family
GKO36_RS09005	COG2433	Pfam Transposase IS66
GKO36_RS09015	COG1196	nuclear chromosome segregation
GKO36_RS09015	COG0741	lytic transglycosylase activity
GKO36_RS09015	COG0739	heme binding
GKO36_RS09180	COG0776	regulation of translation
GKO36_RS09295	COG3655	Transcriptional regulator
GKO36_RS09300	COG3655	Transcriptional regulator
GKO36_RS09400	COG3655	Transcriptional regulator
GKO36_RS09485	COG1793	dna ligase
GKO36_RS09490	COG2135	peptidase activity
GKO36_RS09510	COG4195	phage-related replication protein
GKO36_RS09515	COG3420	alginic acid biosynthetic process
GKO36_RS09515	COG5434	Belongs to the glycosyl hydrolase 28 family
GKO36_RS09545	COG2887	Belongs to the helicase family. UvrD subfamily
GKO36_RS09555	COG0305	Participates in initiation and elongation during chromosome replication
GKO36_RS09560	COG0358	DNA primase activity
GKO36_RS09565	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GKO36_RS09570	COG0587	DNA-directed DNA polymerase activity
GKO36_RS09575	COG3584	3D domain protein
GKO36_RS09590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKO36_RS09700	COG1780	Probably involved in ribonucleotide reductase function
GKO36_RS09705	COG1372	Participates in initiation and elongation during chromosome replication
GKO36_RS09705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKO36_RS09715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKO36_RS09720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKO36_RS09735	COG0756	dUTP diphosphatase activity
GKO36_RS09750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKO36_RS09790	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GKO36_RS09845	COG3331	DNA recombination
GKO36_RS09875	COG2211	Major facilitator Superfamily
GKO36_RS09880	COG3507	Belongs to the glycosyl hydrolase 43 family
GKO36_RS09895	COG1070	Carbohydrate kinase
GKO36_RS09900	COG0574	Belongs to the PEP-utilizing enzyme family
GKO36_RS09900	COG3848	Pyruvate phosphate dikinase
GKO36_RS09920	COG2378	regulation of single-species biofilm formation
GKO36_RS09925	COG2318	DinB family
GKO36_RS09930	COG1064	alcohol dehydrogenase
GKO36_RS09940	COG0456	acetyltransferase
GKO36_RS09945	COG5444	nuclease activity
GKO36_RS10005	COG3397	chitin binding
GKO36_RS10015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKO36_RS10030	COG5434	Belongs to the glycosyl hydrolase 28 family
GKO36_RS10035	COG0756	dUTP diphosphatase activity
GKO36_RS10040	COG4195	phage-related replication protein
GKO36_RS10075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GKO36_RS10085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GKO36_RS10105	COG0785	Cytochrome C biogenesis protein
GKO36_RS10110	COG2201	protein-glutamate methylesterase activity
GKO36_RS10115	COG4846	Membrane protein involved in cytochrome C biogenesis
GKO36_RS10125	COG0071	Belongs to the small heat shock protein (HSP20) family
GKO36_RS10140	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GKO36_RS10145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKO36_RS10165	COG0824	Thioesterase
GKO36_RS10175	COG4841	protein insertion into membrane
GKO36_RS10185	COG1832	CoA-binding protein
GKO36_RS10190	COG0187	DNA topoisomerase II activity
GKO36_RS10195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKO36_RS10205	COG1115	amino acid carrier protein
GKO36_RS10215	COG1063	alcohol dehydrogenase
GKO36_RS10220	COG0800	Aldolase
GKO36_RS10225	COG1312	Catalyzes the dehydration of D-mannonate
GKO36_RS10230	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS10235	COG1609	Transcriptional regulator
GKO36_RS10240	COG2271	Major facilitator Superfamily
GKO36_RS10290	COG2205	protein histidine kinase activity
GKO36_RS10295	COG0745	RESPONSE REGULATOR receiver
GKO36_RS10305	COG3507	Belongs to the glycosyl hydrolase 43 family
GKO36_RS10330	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS10335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GKO36_RS10340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GKO36_RS10345	COG2610	gluconate transmembrane transporter activity
GKO36_RS10350	COG2124	cytochrome p450
GKO36_RS10370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GKO36_RS10380	COG2246	polysaccharide biosynthetic process
GKO36_RS10385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GKO36_RS10390	COG0586	Pfam SNARE associated Golgi protein
GKO36_RS10395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GKO36_RS10400	COG1024	Enoyl-CoA hydratase
GKO36_RS10405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GKO36_RS10410	COG0511	ligase activity, forming carbon-carbon bonds
GKO36_RS10415	COG0439	Biotin carboxylase
GKO36_RS10420	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS10425	COG1960	acyl-CoA dehydrogenase activity
GKO36_RS10430	COG1649	PFAM Uncharacterised BCR, COG1649
GKO36_RS10440	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GKO36_RS10440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS10445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS10450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS10455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS10460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS10465	COG2027	D-alanyl-D-alanine carboxypeptidase
GKO36_RS10470	COG2017	converts alpha-aldose to the beta-anomer
GKO36_RS10475	COG0534	Mate efflux family protein
GKO36_RS10490	COG0582	viral genome integration into host DNA
GKO36_RS10495	COG0166	Belongs to the GPI family
GKO36_RS10500	COG0405	Gamma-glutamyltransferase
GKO36_RS10505	COG2814	Major facilitator Superfamily
GKO36_RS10510	COG0640	Transcriptional regulator
GKO36_RS10515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKO36_RS10525	COG0604	alcohol dehydrogenase
GKO36_RS10535	COG0493	'glutamate synthase
GKO36_RS10540	COG0069	glutamate synthase activity
GKO36_RS10540	COG0070	glutamate synthase
GKO36_RS10540	COG0067	glutamate synthase
GKO36_RS10545	COG0583	DNA-binding transcription factor activity
GKO36_RS10550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKO36_RS10565	COG0300	oxidoreductase activity
GKO36_RS10570	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKO36_RS10580	COG2814	Major facilitator Superfamily
GKO36_RS10585	COG1070	Carbohydrate kinase
GKO36_RS10590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GKO36_RS10595	COG0243	molybdopterin cofactor binding
GKO36_RS10625	COG5444	nuclease activity
GKO36_RS10630	COG4974	Belongs to the 'phage' integrase family
GKO36_RS10670	COG5632	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS10675	COG4824	toxin secretion phage lysis holin
GKO36_RS10695	COG5434	Belongs to the glycosyl hydrolase 28 family
GKO36_RS10710	COG5280	Phage tail tape measure protein TP901
GKO36_RS10710	COG3953	SLT domain
GKO36_RS10850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKO36_RS10855	COG2207	Transcriptional regulator
GKO36_RS10855	COG0662	Cupin 2, conserved barrel domain protein
GKO36_RS10860	COG1309	transcriptional regulator
GKO36_RS10865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKO36_RS10875	COG0640	Transcriptional regulator
GKO36_RS10880	COG0741	lytic transglycosylase activity
GKO36_RS10885	COG2322	membrane
GKO36_RS10900	COG1619	proteins homologs of microcin C7 resistance protein MccF
GKO36_RS10910	COG1388	LysM domain
GKO36_RS10910	COG3584	3D domain protein
GKO36_RS10915	COG0514	ATP-dependent DNA helicase (RecQ)
GKO36_RS10925	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GKO36_RS10930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GKO36_RS10945	COG0071	Belongs to the small heat shock protein (HSP20) family
GKO36_RS10975	COG1012	belongs to the aldehyde dehydrogenase family
GKO36_RS10980	COG1657	PFAM Prenyltransferase squalene oxidase
GKO36_RS10985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GKO36_RS10990	COG0733	neurotransmitter:sodium symporter activity
GKO36_RS10995	COG0385	Bile acid
GKO36_RS11000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKO36_RS11005	COG0508	dehydrogenase complex catalyzes the overall conversion of
GKO36_RS11015	COG4548	von Willebrand factor, type A
GKO36_RS11020	COG0714	Associated with various cellular activities
GKO36_RS11025	COG2032	superoxide dismutase activity
GKO36_RS11030	COG0791	NLP P60 protein
GKO36_RS11030	COG1388	LysM domain
GKO36_RS11035	COG1819	glycosyl
GKO36_RS11040	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKO36_RS11045	COG0534	Mate efflux family protein
GKO36_RS11050	COG1366	Belongs to the anti-sigma-factor antagonist family
GKO36_RS11055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GKO36_RS11060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GKO36_RS11070	COG2962	Rard protein
GKO36_RS11085	COG1942	4-Oxalocrotonate Tautomerase
GKO36_RS11095	COG1733	regulation of RNA biosynthetic process
GKO36_RS11100	COG0778	Nitroreductase
GKO36_RS11105	COG0400	carboxylic ester hydrolase activity
GKO36_RS11110	COG0346	lactoylglutathione lyase activity
GKO36_RS11120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKO36_RS11130	COG2723	6-phospho-beta-galactosidase activity
GKO36_RS11135	COG2188	Transcriptional regulator
GKO36_RS11140	COG3409	Peptidoglycan-binding domain 1 protein
GKO36_RS11140	COG0793	Belongs to the peptidase S41A family
GKO36_RS11145	COG2226	methyltransferase
GKO36_RS11155	COG1876	peptidase activity
GKO36_RS11175	COG0671	phosphoesterase, PA-phosphatase related
GKO36_RS11205	COG1509	lysine 2,3-aminomutase activity
GKO36_RS11210	COG0456	acetyltransferase
GKO36_RS11215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GKO36_RS11220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GKO36_RS11225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GKO36_RS11230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GKO36_RS11235	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GKO36_RS11245	COG0456	acetyltransferase
GKO36_RS11250	COG0463	Glycosyl transferase, family 2
GKO36_RS11265	COG4641	Protein conserved in bacteria
GKO36_RS11275	COG1086	Polysaccharide biosynthesis protein
GKO36_RS11290	COG1846	Transcriptional regulator
GKO36_RS11295	COG4698	Protein conserved in bacteria
GKO36_RS11300	COG2755	lipolytic protein G-D-S-L family
GKO36_RS11305	COG1999	signal sequence binding
GKO36_RS11315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GKO36_RS11320	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GKO36_RS11325	COG1272	protein, Hemolysin III
GKO36_RS11330	COG0204	Acyl-transferase
GKO36_RS11335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKO36_RS11350	COG2521	methyltransferase
GKO36_RS11350	COG2136	Putative SAM-dependent methyltransferase
GKO36_RS11365	COG1413	lyase activity
GKO36_RS11370	COG1418	mRNA catabolic process
GKO36_RS11375	COG0386	Belongs to the glutathione peroxidase family
GKO36_RS11385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKO36_RS11395	COG1278	Cold shock
GKO36_RS11415	COG0328	RNA-DNA hybrid ribonuclease activity
GKO36_RS11420	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GKO36_RS11425	COG0328	RNA-DNA hybrid ribonuclease activity
GKO36_RS11435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKO36_RS11450	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GKO36_RS11460	COG1755	Isoprenylcysteine carboxyl methyltransferase
GKO36_RS11465	COG3424	synthase
GKO36_RS11490	COG1335	isochorismatase
GKO36_RS11530	COG4824	toxin secretion phage lysis holin
GKO36_RS11550	COG5434	Belongs to the glycosyl hydrolase 28 family
GKO36_RS11555	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKO36_RS11565	COG5280	Phage tail tape measure protein TP901
GKO36_RS11565	COG3953	SLT domain
GKO36_RS11675	COG1595	DNA-templated transcription, initiation
GKO36_RS11705	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GKO36_RS11710	COG1484	DNA-dependent DNA replication
GKO36_RS11715	COG3935	DnaD domain protein
GKO36_RS11750	COG3645	SOS response
GKO36_RS11750	COG3646	Phage regulatory protein
GKO36_RS11765	COG3620	sequence-specific DNA binding
GKO36_RS11770	COG0582	viral genome integration into host DNA
GKO36_RS11775	COG2233	PERMEase
GKO36_RS11785	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GKO36_RS11790	COG1199	ATP-dependent helicase activity
GKO36_RS11805	COG0116	Belongs to the methyltransferase superfamily
GKO36_RS11835	COG3359	exonuclease
GKO36_RS11840	COG1111	helicase
GKO36_RS11840	COG1205	dead DEAH box helicase
GKO36_RS11845	COG2190	(PTS) system
GKO36_RS11850	COG0071	Belongs to the small heat shock protein (HSP20) family
GKO36_RS11890	COG4499	WXG100 protein secretion system (Wss), protein YukC
GKO36_RS11890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GKO36_RS11900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKO36_RS11905	COG3935	DnaD domain protein
GKO36_RS11915	COG0436	Aminotransferase
GKO36_RS11920	COG5353	protein conserved in bacteria
GKO36_RS11930	COG1199	ATP-dependent helicase activity
GKO36_RS11930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GKO36_RS11960	COG0438	transferase activity, transferring glycosyl groups
GKO36_RS11965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GKO36_RS11980	COG1694	Mazg nucleotide pyrophosphohydrolase
GKO36_RS11985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKO36_RS11990	COG2140	Oxalate decarboxylase
GKO36_RS12000	COG4347	Protein of unknown function (DUF1405)
GKO36_RS12005	COG2010	Cytochrome c
GKO36_RS12005	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GKO36_RS12010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GKO36_RS12015	COG0723	plastoquinol--plastocyanin reductase activity
GKO36_RS12030	COG0457	Tetratricopeptide repeat
GKO36_RS12040	COG0287	Prephenate dehydrogenase
GKO36_RS12075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GKO36_RS12080	COG4401	Chorismate mutase type I
GKO36_RS12095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GKO36_RS12100	COG0105	UTP biosynthetic process
GKO36_RS12105	COG0142	geranyltranstransferase activity
GKO36_RS12115	COG0142	geranyltranstransferase activity
GKO36_RS12130	COG0776	regulation of translation
GKO36_RS12135	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GKO36_RS12175	COG0539	negative regulation of cytoplasmic translation
GKO36_RS12190	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GKO36_RS12195	COG2959	enzyme of heme biosynthesis
GKO36_RS12200	COG3409	Peptidoglycan-binding domain 1 protein
GKO36_RS12200	COG3773	Cell wall hydrolase
GKO36_RS12205	COG2339	peptidase activity
GKO36_RS12210	COG0492	ferredoxin-NADP+ reductase activity
GKO36_RS12215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GKO36_RS12220	COG4862	establishment of competence for transformation
GKO36_RS12225	COG1408	metallophosphoesterase
GKO36_RS12235	COG1388	LysM domain
GKO36_RS12240	COG1266	CAAX protease self-immunity
GKO36_RS12245	COG0514	ATP-dependent DNA helicase (RecQ)
GKO36_RS12250	COG4955	Helix-turn-helix domain
GKO36_RS12255	COG1141	Ferredoxin
GKO36_RS12260	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKO36_RS12265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GKO36_RS12275	COG1595	DNA-templated transcription, initiation
GKO36_RS12280	COG5002	protein histidine kinase activity
GKO36_RS12285	COG0745	RESPONSE REGULATOR receiver
GKO36_RS12290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GKO36_RS12295	COG1333	cytochrome c biogenesis protein
GKO36_RS12300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKO36_RS12305	COG1187	pseudouridine synthase activity
GKO36_RS12310	COG0700	Nucleoside recognition
GKO36_RS12315	COG2715	membrane protein required for spore maturation
GKO36_RS12320	COG1686	Belongs to the peptidase S11 family
GKO36_RS12345	COG1547	Domain of unknown function (DUF309)
GKO36_RS12350	COG0456	acetyltransferase
GKO36_RS12365	COG0307	riboflavin synthase, alpha
GKO36_RS12370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKO36_RS12370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKO36_RS12380	COG0681	Belongs to the peptidase S26 family
GKO36_RS12390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKO36_RS12395	COG4086	secreted protein
GKO36_RS12400	COG0019	diaminopimelate decarboxylase activity
GKO36_RS12405	COG0697	spore germination
GKO36_RS12420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKO36_RS12440	COG1191	sigma factor activity
GKO36_RS12450	COG1366	Belongs to the anti-sigma-factor antagonist family
GKO36_RS12455	COG1686	Belongs to the peptidase S11 family
GKO36_RS12460	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GKO36_RS12465	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GKO36_RS12470	COG4974	Belongs to the 'phage' integrase family
GKO36_RS12480	COG0735	belongs to the Fur family
GKO36_RS12485	COG1300	Membrane
GKO36_RS12500	COG0281	malic enzyme
GKO36_RS12505	COG1757	Na H antiporter
GKO36_RS12510	COG1027	Aspartate ammonia-lyase
GKO36_RS12515	COG0252	asparaginase activity
GKO36_RS12520	COG1396	sequence-specific DNA binding
GKO36_RS12525	COG1379	DNA repair
GKO36_RS12530	COG0494	nUDIX hydrolase
GKO36_RS12540	COG0667	Aldo Keto reductase
GKO36_RS12550	COG1073	alpha beta
GKO36_RS12560	COG4918	Iron-sulphur cluster biosynthesis
GKO36_RS12565	COG0456	acetyltransferase
GKO36_RS12565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKO36_RS12570	COG2329	Antibiotic biosynthesis monooxygenase
GKO36_RS12575	COG0456	acetyltransferase
GKO36_RS12580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKO36_RS12595	COG0628	permease
GKO36_RS12605	COG0346	lactoylglutathione lyase activity
GKO36_RS12615	COG3048	D-serine ammonia-lyase activity
GKO36_RS12620	COG0300	oxidoreductase activity
GKO36_RS12625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKO36_RS12630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKO36_RS12635	COG1024	Enoyl-CoA hydratase
GKO36_RS12640	COG3425	synthase
GKO36_RS12645	COG2124	cytochrome p450
GKO36_RS12650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS12650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKO36_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS12650	COG3321	synthase
GKO36_RS12650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS12655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKO36_RS12655	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS12655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS12655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS12655	COG3321	synthase
GKO36_RS12660	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS12660	COG0300	oxidoreductase activity
GKO36_RS12660	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS12660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS12660	COG3321	synthase
GKO36_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS12665	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS12665	COG0300	oxidoreductase activity
GKO36_RS12665	COG3321	synthase
GKO36_RS12665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS12670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS12670	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS12670	COG3321	synthase
GKO36_RS12670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS12670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKO36_RS12675	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS12675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS12675	COG3321	synthase
GKO36_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS12675	COG0300	oxidoreductase activity
GKO36_RS12680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKO36_RS12680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS12680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKO36_RS12680	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS12680	COG3321	synthase
GKO36_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS12690	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS12705	COG2070	2-Nitropropane dioxygenase
GKO36_RS12705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GKO36_RS12710	COG0250	Participates in transcription elongation, termination and antitermination
GKO36_RS12735	COG0596	Alpha beta hydrolase
GKO36_RS12750	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKO36_RS12755	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKO36_RS12770	COG0706	membrane insertase activity
GKO36_RS12775	COG2195	Cleaves the N-terminal amino acid of tripeptides
GKO36_RS12780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GKO36_RS12785	COG0346	lactoylglutathione lyase activity
GKO36_RS12795	COG1376	ErfK ybiS ycfS ynhG family protein
GKO36_RS12800	COG4129	membrane
GKO36_RS12805	COG1126	abc transporter atp-binding protein
GKO36_RS12810	COG0765	amino acid transport
GKO36_RS12815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKO36_RS12825	COG1597	lipid kinase activity
GKO36_RS12830	COG0508	dehydrogenase complex catalyzes the overall conversion of
GKO36_RS12835	COG0022	dehydrogenase e1 component
GKO36_RS12840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GKO36_RS12845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GKO36_RS12850	COG3426	butyrate kinase activity
GKO36_RS12855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GKO36_RS12860	COG0280	phosphate acetyltransferase
GKO36_RS12865	COG3829	transcription factor binding
GKO36_RS12865	COG3290	protein histidine kinase activity
GKO36_RS12875	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GKO36_RS12880	COG2079	MmgE PrpD family protein
GKO36_RS12885	COG0372	Belongs to the citrate synthase family
GKO36_RS12890	COG1960	acyl-CoA dehydrogenase activity
GKO36_RS12895	COG1250	3-hydroxyacyl-CoA dehydrogenase
GKO36_RS12900	COG0183	Belongs to the thiolase family
GKO36_RS12905	COG0584	glycerophosphoryl diester phosphodiesterase
GKO36_RS12935	COG1902	pentaerythritol trinitrate reductase activity
GKO36_RS12950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKO36_RS12955	COG0745	RESPONSE REGULATOR receiver
GKO36_RS12960	COG0750	zinc metalloprotease
GKO36_RS12965	COG0497	DNA recombination
GKO36_RS12975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GKO36_RS12985	COG0142	geranyltranstransferase activity
GKO36_RS12995	COG1570	exodeoxyribonuclease VII activity
GKO36_RS13010	COG1302	Protein conserved in bacteria
GKO36_RS13015	COG0439	Biotin carboxylase
GKO36_RS13020	COG0511	ligase activity, forming carbon-carbon bonds
GKO36_RS13060	COG3854	ATPases associated with a variety of cellular activities
GKO36_RS13075	COG0006	proline dipeptidase activity
GKO36_RS13085	COG3872	metal-dependent enzyme
GKO36_RS13095	COG1752	Esterase of the alpha-beta hydrolase superfamily
GKO36_RS13110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKO36_RS13130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GKO36_RS13145	COG1396	sequence-specific DNA binding
GKO36_RS13155	COG0681	Belongs to the peptidase S26 family
GKO36_RS13180	COG4940	Competence protein ComGF
GKO36_RS13190	COG4970	Tfp pilus assembly protein FimT
GKO36_RS13195	COG4537	Required for transformation and DNA binding
GKO36_RS13200	COG1459	type II secretion system
GKO36_RS13205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GKO36_RS13210	COG0598	Magnesium transport protein CorA
GKO36_RS13215	COG1253	flavin adenine dinucleotide binding
GKO36_RS13220	COG1366	Belongs to the anti-sigma-factor antagonist family
GKO36_RS13230	COG1393	Belongs to the ArsC family
GKO36_RS13240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKO36_RS13250	COG0011	TIGRFAM Protein of
GKO36_RS13260	COG2866	Carboxypeptidase
GKO36_RS13265	COG1940	carbohydrate kinase activity
GKO36_RS13270	COG4483	Protein conserved in bacteria
GKO36_RS13275	COG1757	Na H antiporter
GKO36_RS13285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKO36_RS13300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKO36_RS13305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GKO36_RS13310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GKO36_RS13315	COG0581	inorganic phosphate transmembrane transporter activity
GKO36_RS13320	COG0573	inorganic phosphate transmembrane transporter activity
GKO36_RS13325	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GKO36_RS13330	COG0768	penicillin binding
GKO36_RS13335	COG0477	Major facilitator Superfamily
GKO36_RS13340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GKO36_RS13345	COG2839	Protein conserved in bacteria
GKO36_RS13350	COG5521	maltodextrose utilization protein MalA
GKO36_RS13355	COG1388	LysM domain
GKO36_RS13365	COG4709	membrane
GKO36_RS13370	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GKO36_RS13375	COG0735	belongs to the Fur family
GKO36_RS13380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKO36_RS13395	COG0513	Belongs to the DEAD box helicase family
GKO36_RS13410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKO36_RS13415	COG2384	SAM-dependent methyltransferase
GKO36_RS13420	COG2010	Cytochrome c
GKO36_RS13425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKO36_RS13430	COG0358	DNA primase activity
GKO36_RS13445	COG0517	IMP dehydrogenase activity
GKO36_RS13450	COG0751	glycine-tRNA ligase activity
GKO36_RS13470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKO36_RS13475	COG0295	cytidine deaminase activity
GKO36_RS13480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GKO36_RS13490	COG1480	7TM receptor with intracellular HD hydrolase
GKO36_RS13495	COG1702	phosphate starvation-inducible protein PhoH
GKO36_RS13500	COG0561	phosphatase activity
GKO36_RS13515	COG4864	UPF0365 protein
GKO36_RS13520	COG1030	water channel activity
GKO36_RS13525	COG1610	YqeY-like protein
GKO36_RS13535	COG1283	sodium-dependent phosphate transmembrane transporter activity
GKO36_RS13540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GKO36_RS13545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GKO36_RS13575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GKO36_RS13590	COG0860	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS13605	COG1466	dna polymerase III delta subunit
GKO36_RS13620	COG0658	competence protein
GKO36_RS13620	COG2333	competence protein COMEC
GKO36_RS13625	COG2131	deaminase
GKO36_RS13630	COG1596	polysaccharide export
GKO36_RS13630	COG1555	photosystem II stabilization
GKO36_RS13635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKO36_RS13640	COG2226	methyltransferase
GKO36_RS13645	COG0799	negative regulation of ribosome biogenesis
GKO36_RS13650	COG1713	HD superfamily hydrolase involved in NAD metabolism
GKO36_RS13660	COG1534	Rna-binding protein
GKO36_RS13665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKO36_RS13670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKO36_RS13675	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GKO36_RS13685	COG2755	lipolytic protein G-D-S-L family
GKO36_RS13695	COG0398	Pfam SNARE associated Golgi protein
GKO36_RS13720	COG3708	Transcriptional regulator
GKO36_RS13720	COG2207	Transcriptional regulator
GKO36_RS13725	COG0583	DNA-binding transcription factor activity
GKO36_RS13740	COG5002	protein histidine kinase activity
GKO36_RS13740	COG0642	Histidine kinase
GKO36_RS13745	COG0745	RESPONSE REGULATOR receiver
GKO36_RS13750	COG2311	Membrane
GKO36_RS13760	COG0454	-acetyltransferase
GKO36_RS13765	COG0563	adenylate kinase activity
GKO36_RS13775	COG2814	Major facilitator Superfamily
GKO36_RS13785	COG0456	acetyltransferase
GKO36_RS13790	COG2318	DinB family
GKO36_RS13800	COG0561	phosphatase activity
GKO36_RS13805	COG0561	phosphatase activity
GKO36_RS13815	COG1482	cell wall glycoprotein biosynthetic process
GKO36_RS13820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKO36_RS13820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKO36_RS13820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKO36_RS13825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKO36_RS13825	COG3711	transcriptional antiterminator
GKO36_RS13835	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKO36_RS13840	COG0583	DNA-binding transcription factor activity
GKO36_RS13845	COG2814	Major facilitator Superfamily
GKO36_RS13850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GKO36_RS13850	COG2124	cytochrome p450
GKO36_RS13855	COG1309	transcriptional regulator
GKO36_RS13860	COG2226	methyltransferase
GKO36_RS13875	COG2116	formate transmembrane transporter activity
GKO36_RS13880	COG5609	conserved protein (DUF2294)
GKO36_RS13885	COG3383	formate dehydrogenase (NAD+) activity
GKO36_RS13890	COG2427	Protein of unknown function (DUF1641)
GKO36_RS13900	COG0626	cystathionine gamma-synthase activity
GKO36_RS13905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GKO36_RS13930	COG0768	penicillin binding
GKO36_RS13945	COG0826	peptidase U32
GKO36_RS13950	COG0826	peptidase U32
GKO36_RS13955	COG4122	O-methyltransferase activity
GKO36_RS13960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKO36_RS13975	COG4472	Bacterial protein of unknown function (DUF965)
GKO36_RS13985	COG0628	permease
GKO36_RS13990	COG1126	abc transporter atp-binding protein
GKO36_RS13995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKO36_RS14000	COG0765	amino acid transport
GKO36_RS14005	COG0765	amino acid transport
GKO36_RS14020	COG3881	PFAM PRC-barrel domain
GKO36_RS14025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GKO36_RS14030	COG0457	Tetratricopeptide repeat
GKO36_RS14040	COG1104	cysteine desulfurase activity
GKO36_RS14045	COG1959	2 iron, 2 sulfur cluster binding
GKO36_RS14050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GKO36_RS14055	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GKO36_RS14080	COG4991	sh3 domain protein
GKO36_RS14080	COG0860	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS14080	COG3103	Sh3 type 3 domain protein
GKO36_RS14090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKO36_RS14100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GKO36_RS14100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GKO36_RS14105	COG5416	Lipopolysaccharide assembly protein A domain
GKO36_RS14110	COG0490	domain, Protein
GKO36_RS14115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GKO36_RS14115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GKO36_RS14125	COG2244	polysaccharide biosynthetic process
GKO36_RS14130	COG2323	membrane
GKO36_RS14140	COG1862	Preprotein translocase
GKO36_RS14180	COG1388	LysM domain
GKO36_RS14190	COG0157	Belongs to the NadC ModD family
GKO36_RS14195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GKO36_RS14200	COG1104	cysteine desulfurase activity
GKO36_RS14205	COG1827	regulation of RNA biosynthetic process
GKO36_RS14210	COG0077	Prephenate dehydratase
GKO36_RS14225	COG3290	protein histidine kinase activity
GKO36_RS14230	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GKO36_RS14235	COG2868	ribosomal protein
GKO36_RS14245	COG1994	Peptidase M50
GKO36_RS14250	COG0739	heme binding
GKO36_RS14255	COG2894	cell division
GKO36_RS14265	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GKO36_RS14275	COG1077	Cell shape determining protein MreB Mrl
GKO36_RS14295	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GKO36_RS14300	COG0285	dihydrofolate synthase activity
GKO36_RS14305	COG0525	valine-tRNA ligase activity
GKO36_RS14315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GKO36_RS14320	COG1388	LysM domain
GKO36_RS14330	COG0113	porphobilinogen synthase activity
GKO36_RS14335	COG1587	Uroporphyrinogen-III synthase
GKO36_RS14345	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GKO36_RS14365	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GKO36_RS14370	COG0470	DNA polymerase III
GKO36_RS14370	COG1067	ATP-dependent peptidase activity
GKO36_RS14385	COG0457	Tetratricopeptide repeat
GKO36_RS14385	COG1477	protein flavinylation
GKO36_RS14400	COG0473	3-isopropylmalate dehydrogenase activity
GKO36_RS14415	COG0440	acetolactate synthase activity
GKO36_RS14420	COG0028	Belongs to the TPP enzyme family
GKO36_RS14450	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GKO36_RS14475	COG0622	Phosphoesterase
GKO36_RS14480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKO36_RS14490	COG5401	PFAM Sporulation and spore germination
GKO36_RS14500	COG1846	Transcriptional regulator
GKO36_RS14505	COG2197	response regulator
GKO36_RS14510	COG0824	Thioesterase
GKO36_RS14515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GKO36_RS14520	COG1053	succinate dehydrogenase
GKO36_RS14525	COG2009	succinate dehydrogenase
GKO36_RS14530	COG1719	4-vinyl reductase, 4VR
GKO36_RS14535	COG0527	aspartate kinase activity
GKO36_RS14545	COG3118	belongs to the thioredoxin family
GKO36_RS14550	COG3534	alpha-L-arabinofuranosidase
GKO36_RS14555	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GKO36_RS14560	COG2086	electron transfer activity
GKO36_RS14565	COG1024	Enoyl-CoA hydratase
GKO36_RS14570	COG1309	transcriptional regulator
GKO36_RS14575	COG0318	PFAM AMP-dependent synthetase and ligase
GKO36_RS14585	COG3766	membrane
GKO36_RS14595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GKO36_RS14595	COG1796	DNA polymerase
GKO36_RS14600	COG1286	toxin biosynthetic process
GKO36_RS14615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKO36_RS14615	COG0072	phenylalanine-tRNA ligase activity
GKO36_RS14620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKO36_RS14625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKO36_RS14635	COG3835	regulator
GKO36_RS14640	COG0277	FAD linked oxidase domain protein
GKO36_RS14645	COG0247	lactate metabolic process
GKO36_RS14650	COG1966	Carbon starvation protein
GKO36_RS14655	COG3534	alpha-L-arabinofuranosidase
GKO36_RS14660	COG0395	ABC-type sugar transport system, permease component
GKO36_RS14665	COG1175	transmembrane transport
GKO36_RS14670	COG1653	transport
GKO36_RS14680	COG0647	UMP catabolic process
GKO36_RS14685	COG0235	Class ii aldolase
GKO36_RS14690	COG1069	ribulokinase activity
GKO36_RS14695	COG2160	L-arabinose isomerase activity
GKO36_RS14700	COG3507	Belongs to the glycosyl hydrolase 43 family
GKO36_RS14705	COG1363	Peptidase, m42
GKO36_RS14715	COG3326	Membrane
GKO36_RS14730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKO36_RS14735	COG1346	cytolysis
GKO36_RS14740	COG1380	Effector of murein hydrolase LrgA
GKO36_RS14745	COG3279	Response regulator of the LytR AlgR family
GKO36_RS14750	COG3275	phosphorelay sensor kinase activity
GKO36_RS14755	COG1011	Hydrolase
GKO36_RS14770	COG0398	Pfam SNARE associated Golgi protein
GKO36_RS14775	COG1484	DNA-dependent DNA replication
GKO36_RS14780	COG3611	Membrane attachment protein
GKO36_RS14795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GKO36_RS14800	COG1733	regulation of RNA biosynthetic process
GKO36_RS14805	COG2814	Major facilitator Superfamily
GKO36_RS14810	COG0656	L-ascorbic acid biosynthetic process
GKO36_RS14815	COG0237	dephospho-CoA kinase activity
GKO36_RS14820	COG1971	Probably functions as a manganese efflux pump
GKO36_RS14825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GKO36_RS14830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKO36_RS14830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKO36_RS14835	COG5002	protein histidine kinase activity
GKO36_RS14840	COG0745	RESPONSE REGULATOR receiver
GKO36_RS14850	COG0538	isocitrate dehydrogenase activity
GKO36_RS14855	COG0372	Belongs to the citrate synthase family
GKO36_RS14865	COG0457	Tetratricopeptide repeat
GKO36_RS14895	COG0628	permease
GKO36_RS14900	COG3030	protein affecting phage T7 exclusion by the F plasmid
GKO36_RS14905	COG0469	pyruvate kinase activity
GKO36_RS14925	COG0281	malic enzyme
GKO36_RS14930	COG0587	DNA-directed DNA polymerase activity
GKO36_RS14950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GKO36_RS14960	COG4109	DRTGG domain
GKO36_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS14985	COG0521	Mo-molybdopterin cofactor biosynthetic process
GKO36_RS14995	COG0827	DNA restriction-modification system
GKO36_RS15000	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKO36_RS15005	COG3874	Sporulation protein YtfJ
GKO36_RS15015	COG1714	RDD family
GKO36_RS15020	COG0616	signal peptide processing
GKO36_RS15025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKO36_RS15030	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GKO36_RS15035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GKO36_RS15050	COG1104	cysteine desulfurase activity
GKO36_RS15055	COG1114	Component of the transport system for branched-chain amino acids
GKO36_RS15065	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GKO36_RS15070	COG1309	transcriptional regulator
GKO36_RS15075	COG1956	GAF domain-containing protein
GKO36_RS15080	COG2199	diguanylate cyclase activity
GKO36_RS15080	COG2203	Gaf domain
GKO36_RS15090	COG1012	belongs to the aldehyde dehydrogenase family
GKO36_RS15095	COG4282	regulation of fungal-type cell wall biogenesis
GKO36_RS15145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GKO36_RS15145	COG1017	nitric oxide dioxygenase activity
GKO36_RS15155	COG0693	protein deglycase activity
GKO36_RS15170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKO36_RS15175	COG1378	Sugar-specific transcriptional regulator TrmB
GKO36_RS15195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GKO36_RS15200	COG0454	-acetyltransferase
GKO36_RS15205	COG0517	IMP dehydrogenase activity
GKO36_RS15210	COG0123	including yeast histone deacetylase and acetoin utilization protein
GKO36_RS15215	COG1360	Flagellar Motor Protein
GKO36_RS15220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GKO36_RS15225	COG1609	Transcriptional regulator
GKO36_RS15230	COG1605	Chorismate mutase
GKO36_RS15230	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GKO36_RS15235	COG3118	belongs to the thioredoxin family
GKO36_RS15240	COG4980	gas vesicle protein
GKO36_RS15245	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKO36_RS15255	COG1674	ftsk spoiiie
GKO36_RS15260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKO36_RS15270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKO36_RS15290	COG1363	Peptidase, m42
GKO36_RS15295	COG5584	Small secreted protein
GKO36_RS15300	COG0281	malic enzyme
GKO36_RS15305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKO36_RS15320	COG0510	thiamine kinase activity
GKO36_RS15325	COG1597	lipid kinase activity
GKO36_RS15335	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GKO36_RS15340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GKO36_RS15345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GKO36_RS15350	COG2252	PERMEase
GKO36_RS15355	COG4473	ABC transporter
GKO36_RS15360	COG1131	(ABC) transporter
GKO36_RS15365	COG1349	DNA-binding transcription factor activity
GKO36_RS15370	COG1187	pseudouridine synthase activity
GKO36_RS15375	COG2244	polysaccharide biosynthetic process
GKO36_RS15380	COG2081	HI0933 family
GKO36_RS15385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GKO36_RS15395	COG1609	Transcriptional regulator
GKO36_RS15400	COG1653	transport
GKO36_RS15405	COG1175	transmembrane transport
GKO36_RS15410	COG0395	ABC-type sugar transport system, permease component
GKO36_RS15415	COG1486	melibiose metabolic process
GKO36_RS15425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKO36_RS15440	COG2202	Pas domain
GKO36_RS15440	COG1366	Belongs to the anti-sigma-factor antagonist family
GKO36_RS15445	COG2814	Major facilitator Superfamily
GKO36_RS15450	COG5522	Integral membrane protein (intg_mem_TP0381)
GKO36_RS15455	COG0577	efflux transmembrane transporter activity
GKO36_RS15460	COG1136	(ABC) transporter
GKO36_RS15465	COG2205	protein histidine kinase activity
GKO36_RS15470	COG0745	RESPONSE REGULATOR receiver
GKO36_RS15475	COG0577	efflux transmembrane transporter activity
GKO36_RS15480	COG1136	(ABC) transporter
GKO36_RS15500	COG1131	(ABC) transporter
GKO36_RS15505	COG1725	Transcriptional regulator
GKO36_RS15515	COG1242	4 iron, 4 sulfur cluster binding
GKO36_RS15520	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GKO36_RS15530	COG0584	glycerophosphoryl diester phosphodiesterase
GKO36_RS15540	COG2267	carboxylic ester hydrolase activity
GKO36_RS15545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GKO36_RS15550	COG1113	amino acid transport
GKO36_RS15555	COG0367	asparagine synthase
GKO36_RS15575	COG1506	peptidase
GKO36_RS15580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GKO36_RS15585	COG1116	anion transmembrane transporter activity
GKO36_RS15590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GKO36_RS15595	COG0494	nUDIX hydrolase
GKO36_RS15600	COG4824	toxin secretion phage lysis holin
GKO36_RS15605	COG0783	Belongs to the Dps family
GKO36_RS15630	COG0288	reversible hydration of carbon dioxide
GKO36_RS15640	COG1271	oxidase subunit
GKO36_RS15645	COG1294	oxidase, subunit
GKO36_RS15655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GKO36_RS15660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GKO36_RS15660	COG1321	iron dependent repressor
GKO36_RS15665	COG1121	(ABC) transporter
GKO36_RS15670	COG0803	Belongs to the bacterial solute-binding protein 9 family
GKO36_RS15675	COG4948	Mandelate Racemase Muconate Lactonizing
GKO36_RS15685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GKO36_RS15690	COG0596	Alpha beta hydrolase
GKO36_RS15700	COG1169	isochorismate synthase
GKO36_RS15705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GKO36_RS15710	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GKO36_RS15835	COG3859	Proton-coupled thiamine transporter YuaJ
GKO36_RS15840	COG2268	Band 7 protein
GKO36_RS15845	COG1585	Membrane protein implicated in regulation of membrane protease activity
GKO36_RS15850	COG2318	DinB family
GKO36_RS15860	COG1454	alcohol dehydrogenase
GKO36_RS15865	COG1012	belongs to the aldehyde dehydrogenase family
GKO36_RS15870	COG1510	regulation of RNA biosynthetic process
GKO36_RS15880	COG0569	domain protein
GKO36_RS15885	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKO36_RS15890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GKO36_RS15890	COG1017	nitric oxide dioxygenase activity
GKO36_RS15925	COG5632	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS15925	COG3409	Peptidoglycan-binding domain 1 protein
GKO36_RS15950	COG5434	Belongs to the glycosyl hydrolase 28 family
GKO36_RS16045	COG0582	viral genome integration into host DNA
GKO36_RS16070	COG1216	Glycosyl transferase, family 2
GKO36_RS16080	COG4195	phage-related replication protein
GKO36_RS16085	COG5434	Belongs to the glycosyl hydrolase 28 family
GKO36_RS16085	COG3420	alginic acid biosynthetic process
GKO36_RS16120	COG1793	dna ligase
GKO36_RS16140	COG1595	DNA-templated transcription, initiation
GKO36_RS16165	COG1388	LysM domain
GKO36_RS16165	COG3584	3D domain protein
GKO36_RS16170	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GKO36_RS16175	COG0756	dUTP diphosphatase activity
GKO36_RS16185	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKO36_RS16190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKO36_RS16200	COG1780	Probably involved in ribonucleotide reductase function
GKO36_RS16235	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GKO36_RS16255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKO36_RS16255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKO36_RS16300	COG3655	Transcriptional regulator
GKO36_RS16325	COG1484	DNA-dependent DNA replication
GKO36_RS16380	COG4974	Belongs to the 'phage' integrase family
GKO36_RS16395	COG0628	permease
GKO36_RS16400	COG0673	inositol 2-dehydrogenase activity
GKO36_RS16405	COG0693	protein deglycase activity
GKO36_RS16410	COG0840	transmembrane signaling receptor activity
GKO36_RS16415	COG0840	transmembrane signaling receptor activity
GKO36_RS16420	COG0840	transmembrane signaling receptor activity
GKO36_RS16425	COG0840	transmembrane signaling receptor activity
GKO36_RS16440	COG2070	2-Nitropropane dioxygenase
GKO36_RS16445	COG0432	Pfam Uncharacterised protein family UPF0047
GKO36_RS16450	COG0366	Alpha amylase catalytic
GKO36_RS16455	COG1253	flavin adenine dinucleotide binding
GKO36_RS16460	COG2738	Putative neutral zinc metallopeptidase
GKO36_RS16475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GKO36_RS16500	COG1335	isochorismatase
GKO36_RS16505	COG1979	alcohol dehydrogenase
GKO36_RS16510	COG1979	alcohol dehydrogenase
GKO36_RS16515	COG2155	Conserved Protein
GKO36_RS16520	COG1098	S1 RNA binding domain
GKO36_RS16525	COG0436	Aminotransferase
GKO36_RS16530	COG1522	sequence-specific DNA binding
GKO36_RS16535	COG2267	carboxylic ester hydrolase activity
GKO36_RS16545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GKO36_RS16550	COG2205	protein histidine kinase activity
GKO36_RS16560	COG5018	Exonuclease
GKO36_RS16565	COG2814	Major facilitator Superfamily
GKO36_RS16570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GKO36_RS16575	COG3011	Protein conserved in bacteria
GKO36_RS16585	COG3290	protein histidine kinase activity
GKO36_RS16590	COG4565	transcriptional regulatory protein
GKO36_RS16595	COG1744	ABC transporter substrate-binding protein PnrA-like
GKO36_RS16600	COG3845	ABC transporter
GKO36_RS16605	COG4603	Belongs to the binding-protein-dependent transport system permease family
GKO36_RS16610	COG1079	Belongs to the binding-protein-dependent transport system permease family
GKO36_RS16620	COG2111	Na H antiporter
GKO36_RS16620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GKO36_RS16625	COG2111	Na H antiporter
GKO36_RS16630	COG1006	Multisubunit Na H antiporter MnhC subunit
GKO36_RS16635	COG0651	ATP synthesis coupled electron transport
GKO36_RS16640	COG1863	multisubunit Na H antiporter MnhE subunit
GKO36_RS16645	COG2212	antiporter activity
GKO36_RS16650	COG1320	monovalent cation:proton antiporter activity
GKO36_RS16655	COG2050	protein possibly involved in aromatic compounds catabolism
GKO36_RS16660	COG2197	response regulator
GKO36_RS16665	COG4585	Histidine kinase
GKO36_RS16675	COG0142	geranyltranstransferase activity
GKO36_RS16690	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GKO36_RS16695	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKO36_RS16700	COG1335	isochorismatase
GKO36_RS16705	COG5506	Protein of unknown function (DUF1694)
GKO36_RS16720	COG0628	permease
GKO36_RS16730	COG1418	mRNA catabolic process
GKO36_RS16735	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS16745	COG1511	domain protein
GKO36_RS16750	COG0433	COG0433 Predicted ATPase
GKO36_RS16750	COG1674	ftsk spoiiie
GKO36_RS16755	COG4499	WXG100 protein secretion system (Wss), protein YukC
GKO36_RS16760	COG5417	Belongs to the EsaB family
GKO36_RS16765	COG4842	Belongs to the WXG100 family
GKO36_RS16770	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GKO36_RS16770	COG2508	Transcriptional regulator
GKO36_RS16775	COG0686	Belongs to the AlaDH PNT family
GKO36_RS16780	COG5634	Uncharacterized conserved protein (DUF2278)
GKO36_RS16785	COG3251	PFAM MbtH domain protein
GKO36_RS16790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKO36_RS16795	COG3433	isochorismatase activity
GKO36_RS16795	COG1535	isochorismatase
GKO36_RS16800	COG1021	2,3-dihydroxybenzoate-AMP ligase
GKO36_RS16805	COG1169	isochorismate synthase
GKO36_RS16810	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS16815	COG2819	hydrolase of the alpha beta superfamily
GKO36_RS16820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GKO36_RS16825	COG1268	BioY protein
GKO36_RS16830	COG2056	Na+-H+ antiporter family
GKO36_RS16840	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GKO36_RS16845	COG3584	3D domain protein
GKO36_RS16860	COG1252	NADH dehydrogenase
GKO36_RS16890	COG1131	(ABC) transporter
GKO36_RS16910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKO36_RS16915	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GKO36_RS16930	COG0316	Belongs to the HesB IscA family
GKO36_RS16940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKO36_RS16950	COG1252	NADH dehydrogenase
GKO36_RS16955	COG4837	Protein of unknown function (DUF1462)
GKO36_RS16960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GKO36_RS16965	COG4946	Tricorn protease homolog
GKO36_RS16965	COG0823	Involved in the tonB-independent uptake of proteins
GKO36_RS16965	COG1506	peptidase
GKO36_RS16975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GKO36_RS16980	COG0460	homoserine dehydrogenase
GKO36_RS16985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GKO36_RS16990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GKO36_RS16995	COG0647	UMP catabolic process
GKO36_RS17000	COG2445	Protein of unknown function DUF86
GKO36_RS17005	COG4470	Protein conserved in bacteria
GKO36_RS17015	COG0739	heme binding
GKO36_RS17025	COG0737	Belongs to the 5'-nucleotidase family
GKO36_RS17030	COG0730	response to heat
GKO36_RS17035	COG1801	Protein of unknown function DUF72
GKO36_RS17050	COG2508	Transcriptional regulator
GKO36_RS17055	COG0457	Tetratricopeptide repeat
GKO36_RS17065	COG2814	Major facilitator Superfamily
GKO36_RS17070	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GKO36_RS17075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GKO36_RS17080	COG2356	endonuclease I
GKO36_RS17085	COG3842	ATPase activity
GKO36_RS17090	COG2188	Transcriptional regulator
GKO36_RS17095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKO36_RS17100	COG0395	ABC-type sugar transport system, permease component
GKO36_RS17105	COG1175	transmembrane transport
GKO36_RS17110	COG1653	transport
GKO36_RS17115	COG2222	sugar isomerase
GKO36_RS17120	COG0789	Transcriptional regulator
GKO36_RS17145	COG0322	excinuclease ABC activity
GKO36_RS17150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKO36_RS17170	COG3409	Peptidoglycan-binding domain 1 protein
GKO36_RS17175	COG0719	Fe-S assembly protein
GKO36_RS17180	COG0822	iron-sulfur transferase activity
GKO36_RS17185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKO36_RS17190	COG0719	Fe-S assembly protein
GKO36_RS17195	COG0396	ATPase activity
GKO36_RS17205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GKO36_RS17210	COG1464	Belongs to the NlpA lipoprotein family
GKO36_RS17215	COG2011	ABC-type metal ion transport system permease component
GKO36_RS17220	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKO36_RS17230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKO36_RS17235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKO36_RS17250	COG1393	Belongs to the ArsC family
GKO36_RS17255	COG1960	acyl-CoA dehydrogenase activity
GKO36_RS17260	COG0183	Belongs to the thiolase family
GKO36_RS17265	COG1250	3-hydroxyacyl-CoA dehydrogenase
GKO36_RS17265	COG1024	Enoyl-CoA hydratase
GKO36_RS17285	COG5577	PFAM Coat F domain
GKO36_RS17290	COG1846	Transcriptional regulator
GKO36_RS17295	COG0477	Major facilitator Superfamily
GKO36_RS17300	COG0583	DNA-binding transcription factor activity
GKO36_RS17320	COG1120	ATPase activity
GKO36_RS17335	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS17340	COG0783	Belongs to the Dps family
GKO36_RS17345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKO36_RS17350	COG0745	RESPONSE REGULATOR receiver
GKO36_RS17355	COG2205	protein histidine kinase activity
GKO36_RS17355	COG2770	Histidine kinase
GKO36_RS17365	COG1309	transcriptional regulator
GKO36_RS17370	COG0114	fumarate hydratase activity
GKO36_RS17380	COG0697	spore germination
GKO36_RS17385	COG0814	amino acid
GKO36_RS17395	COG2197	response regulator
GKO36_RS17400	COG4585	Histidine kinase
GKO36_RS17405	COG4758	membrane
GKO36_RS17410	COG3595	metallopeptidase activity
GKO36_RS17415	COG1842	Phage shock protein A
GKO36_RS17420	COG4758	membrane
GKO36_RS17425	COG2814	Major facilitator Superfamily
GKO36_RS17430	COG2096	Adenosyltransferase
GKO36_RS17435	COG1120	ATPase activity
GKO36_RS17440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKO36_RS17445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GKO36_RS17450	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS17455	COG3386	PFAM SMP-30 Gluconolaconase
GKO36_RS17460	COG2205	protein histidine kinase activity
GKO36_RS17465	COG0745	RESPONSE REGULATOR receiver
GKO36_RS17475	COG1191	sigma factor activity
GKO36_RS17485	COG2140	Oxalate decarboxylase
GKO36_RS17495	COG1120	ATPase activity
GKO36_RS17500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKO36_RS17505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKO36_RS17510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GKO36_RS17515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GKO36_RS17520	COG0531	amino acid
GKO36_RS17530	COG1988	membrane-bound metal-dependent
GKO36_RS17535	COG1368	sulfuric ester hydrolase activity
GKO36_RS17540	COG1910	domain protein
GKO36_RS17545	COG0725	ABC transporter, periplasmic molybdate-binding protein
GKO36_RS17550	COG4149	molybdate abc transporter
GKO36_RS17555	COG2197	response regulator
GKO36_RS17560	COG3850	Histidine kinase
GKO36_RS17565	COG1131	(ABC) transporter
GKO36_RS17575	COG0842	Transport permease protein
GKO36_RS17580	COG0656	L-ascorbic acid biosynthetic process
GKO36_RS17600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GKO36_RS17605	COG3973	AAA domain
GKO36_RS17610	COG2860	membrane
GKO36_RS17620	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GKO36_RS17625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GKO36_RS17630	COG2217	Heavy metal translocating P-type atpase
GKO36_RS17635	COG2217	Heavy metal translocating P-type atpase
GKO36_RS17640	COG2608	mercury ion transmembrane transporter activity
GKO36_RS17645	COG1937	Protein conserved in bacteria
GKO36_RS17650	COG0673	inositol 2-dehydrogenase activity
GKO36_RS17660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKO36_RS17665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GKO36_RS17670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKO36_RS17675	COG1126	abc transporter atp-binding protein
GKO36_RS17680	COG0765	amino acid transport
GKO36_RS17685	COG0765	amino acid transport
GKO36_RS17690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKO36_RS17695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKO36_RS17700	COG0454	-acetyltransferase
GKO36_RS17705	COG0583	DNA-binding transcription factor activity
GKO36_RS17710	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS17715	COG2732	(Barnase) inhibitor
GKO36_RS17720	COG2732	(Barnase) inhibitor
GKO36_RS17735	COG0557	exoribonuclease II activity
GKO36_RS17740	COG1647	Serine aminopeptidase, S33
GKO36_RS17745	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GKO36_RS17750	COG1476	TRANSCRIPTIONal
GKO36_RS17755	COG1396	sequence-specific DNA binding
GKO36_RS17760	COG1396	sequence-specific DNA binding
GKO36_RS17765	COG1733	regulation of RNA biosynthetic process
GKO36_RS17790	COG1131	(ABC) transporter
GKO36_RS17795	COG1174	glycine betaine transport
GKO36_RS17800	COG1732	Glycine betaine
GKO36_RS17810	COG0517	IMP dehydrogenase activity
GKO36_RS17810	COG1125	glycine betaine transport
GKO36_RS17815	COG1510	regulation of RNA biosynthetic process
GKO36_RS17820	COG1174	glycine betaine transport
GKO36_RS17825	COG1732	Glycine betaine
GKO36_RS17830	COG1174	glycine betaine transport
GKO36_RS17835	COG0517	IMP dehydrogenase activity
GKO36_RS17835	COG1125	glycine betaine transport
GKO36_RS17840	COG1510	regulation of RNA biosynthetic process
GKO36_RS17845	COG2095	MarC family integral membrane protein
GKO36_RS17850	COG3064	Membrane
GKO36_RS17855	COG4640	response to antibiotic
GKO36_RS17860	COG0456	acetyltransferase
GKO36_RS17880	COG0126	phosphoglycerate kinase activity
GKO36_RS17885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GKO36_RS17890	COG2390	Transcriptional regulator
GKO36_RS17895	COG2814	Major facilitator Superfamily
GKO36_RS17900	COG1609	Transcriptional regulator
GKO36_RS17905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKO36_RS17910	COG0583	DNA-binding transcription factor activity
GKO36_RS17915	COG0697	spore germination
GKO36_RS17920	COG1113	amino acid transport
GKO36_RS17930	COG1737	Transcriptional regulator
GKO36_RS17935	COG1070	Carbohydrate kinase
GKO36_RS17965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKO36_RS17970	COG2186	Transcriptional regulator
GKO36_RS17975	COG1620	l-lactate permease
GKO36_RS17980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GKO36_RS17990	COG5039	Polysaccharide pyruvyl transferase
GKO36_RS17995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GKO36_RS18000	COG0110	maltose O-acetyltransferase activity
GKO36_RS18005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GKO36_RS18010	COG2244	polysaccharide biosynthetic process
GKO36_RS18015	COG1216	Glycosyl transferase, family 2
GKO36_RS18020	COG5039	Polysaccharide pyruvyl transferase
GKO36_RS18025	COG1216	Glycosyl transferase, family 2
GKO36_RS18035	COG0438	transferase activity, transferring glycosyl groups
GKO36_RS18040	COG1215	transferase activity, transferring glycosyl groups
GKO36_RS18045	COG0438	transferase activity, transferring glycosyl groups
GKO36_RS18050	COG1086	Polysaccharide biosynthesis protein
GKO36_RS18055	COG0489	protein tyrosine kinase activity
GKO36_RS18060	COG3944	biosynthesis protein
GKO36_RS18065	COG1396	sequence-specific DNA binding
GKO36_RS18070	COG2272	Belongs to the type-B carboxylesterase lipase family
GKO36_RS18080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKO36_RS18085	COG2364	Membrane
GKO36_RS18090	COG0456	acetyltransferase
GKO36_RS18095	COG3479	Phenolic acid decarboxylase
GKO36_RS18150	COG2223	nitrite transmembrane transporter activity
GKO36_RS18155	COG1609	Transcriptional regulator
GKO36_RS18165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GKO36_RS18170	COG0366	Alpha amylase catalytic
GKO36_RS18175	COG1554	hydrolase, family 65, central catalytic
GKO36_RS18180	COG5521	maltodextrose utilization protein MalA
GKO36_RS18185	COG3833	ABC-type maltose transport systems, permease component
GKO36_RS18190	COG1175	transmembrane transport
GKO36_RS18195	COG2182	Extracellular solute-binding protein
GKO36_RS18200	COG0366	Alpha amylase catalytic
GKO36_RS18205	COG1609	Transcriptional regulator
GKO36_RS18210	COG1611	Belongs to the LOG family
GKO36_RS18215	COG1694	Mazg nucleotide pyrophosphohydrolase
GKO36_RS18220	COG0659	secondary active sulfate transmembrane transporter activity
GKO36_RS18225	COG0288	reversible hydration of carbon dioxide
GKO36_RS18230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKO36_RS18235	COG4290	ribonuclease
GKO36_RS18240	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GKO36_RS18245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKO36_RS18255	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GKO36_RS18265	COG1051	belongs to the nudix hydrolase family
GKO36_RS18270	COG0492	ferredoxin-NADP+ reductase activity
GKO36_RS18275	COG3883	PFAM NLP P60 protein
GKO36_RS18275	COG0791	NLP P60 protein
GKO36_RS18280	COG0457	Tetratricopeptide repeat
GKO36_RS18285	COG5002	protein histidine kinase activity
GKO36_RS18290	COG0745	RESPONSE REGULATOR receiver
GKO36_RS18300	COG1132	(ABC) transporter
GKO36_RS18305	COG0140	phosphoribosyl-ATP diphosphatase activity
GKO36_RS18305	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GKO36_RS18330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GKO36_RS18345	COG4990	cell redox homeostasis
GKO36_RS18350	COG0110	maltose O-acetyltransferase activity
GKO36_RS18370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKO36_RS18380	COG2188	Transcriptional regulator
GKO36_RS18385	COG1309	transcriptional regulator
GKO36_RS18390	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GKO36_RS18395	COG1950	PFAM Membrane protein of
GKO36_RS18400	COG1983	PspC domain protein
GKO36_RS18405	COG3595	metallopeptidase activity
GKO36_RS18420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GKO36_RS18430	COG4897	Protein conserved in bacteria
GKO36_RS18435	COG0574	Belongs to the PEP-utilizing enzyme family
GKO36_RS18435	COG3848	Pyruvate phosphate dikinase
GKO36_RS18440	COG1309	transcriptional regulator
GKO36_RS18445	COG2814	Major facilitator Superfamily
GKO36_RS18480	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS18490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKO36_RS18500	COG3409	Peptidoglycan-binding domain 1 protein
GKO36_RS18500	COG0793	Belongs to the peptidase S41A family
GKO36_RS18505	COG3420	alginic acid biosynthetic process
GKO36_RS18510	COG2177	Part of the ABC transporter FtsEX involved in
GKO36_RS18515	COG2884	Cell division ATP-binding protein ftsE
GKO36_RS18520	COG2010	Cytochrome c
GKO36_RS18525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKO36_RS18540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKO36_RS18555	COG1516	flagellar protein fliS
GKO36_RS18560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GKO36_RS18565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GKO36_RS18585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GKO36_RS18590	COG1256	bacterial-type flagellum assembly
GKO36_RS18590	COG4786	Flagellar basal body rod
GKO36_RS18595	COG3418	PFAM FlgN family protein
GKO36_RS18600	COG2747	anti-sigma28 factor FlgM
GKO36_RS18610	COG1040	competence protein
GKO36_RS18620	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GKO36_RS18625	COG1307	EDD domain protein, DegV family
GKO36_RS18630	COG2197	response regulator
GKO36_RS18635	COG4585	Histidine kinase
GKO36_RS18640	COG1739	Uncharacterized protein family UPF0029
GKO36_RS18645	COG1316	TRANSCRIPTIONal
GKO36_RS18650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKO36_RS18655	COG0438	transferase activity, transferring glycosyl groups
GKO36_RS18660	COG1215	transferase activity, transferring glycosyl groups
GKO36_RS18665	COG3206	protein involved in exopolysaccharide biosynthesis
GKO36_RS18670	COG3307	-O-antigen
GKO36_RS18675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GKO36_RS18680	COG0438	transferase activity, transferring glycosyl groups
GKO36_RS18680	COG0297	glycogen (starch) synthase activity
GKO36_RS18685	COG2244	polysaccharide biosynthetic process
GKO36_RS18695	COG2247	cell wall binding repeat
GKO36_RS18695	COG0860	N-Acetylmuramoyl-L-alanine amidase
GKO36_RS18700	COG2385	sporulation resulting in formation of a cellular spore
GKO36_RS18700	COG2247	cell wall binding repeat
GKO36_RS18710	COG1316	TRANSCRIPTIONal
GKO36_RS18715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GKO36_RS18720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GKO36_RS18725	COG1134	teichoic acid transport
GKO36_RS18730	COG1682	transport, permease protein
GKO36_RS18735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKO36_RS18745	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GKO36_RS18750	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GKO36_RS18755	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKO36_RS18760	COG4193	domain, Protein
GKO36_RS18765	COG1482	cell wall glycoprotein biosynthetic process
GKO36_RS18770	COG0697	spore germination
GKO36_RS18775	COG0814	amino acid
GKO36_RS18785	COG1215	transferase activity, transferring glycosyl groups
GKO36_RS18790	COG2814	Major facilitator Superfamily
GKO36_RS18795	COG1316	TRANSCRIPTIONal
GKO36_RS18800	COG0561	phosphatase activity
GKO36_RS18805	COG2433	Pfam Transposase IS66
GKO36_RS18810	COG0791	NLP P60 protein
GKO36_RS18820	COG2843	Capsule synthesis protein
GKO36_RS18830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKO36_RS18835	COG0697	spore germination
GKO36_RS18840	COG0814	amino acid
GKO36_RS18850	COG1609	Transcriptional regulator
GKO36_RS18855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKO36_RS18865	COG1129	ABC transporter
GKO36_RS18870	COG1172	Belongs to the binding-protein-dependent transport system permease family
GKO36_RS18875	COG1879	ABC-type sugar transport system periplasmic component
GKO36_RS18880	COG3103	Sh3 type 3 domain protein
GKO36_RS18885	COG2249	NAD(P)H dehydrogenase (quinone) activity
GKO36_RS18890	COG3527	Alpha-acetolactate decarboxylase
GKO36_RS18895	COG0028	Belongs to the TPP enzyme family
GKO36_RS18900	COG0583	DNA-binding transcription factor activity
GKO36_RS18905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GKO36_RS18920	COG5337	Spore coat protein CotH
GKO36_RS18930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GKO36_RS18940	COG0405	Gamma-glutamyltransferase
GKO36_RS18945	COG1522	sequence-specific DNA binding
GKO36_RS18950	COG2059	Chromate
GKO36_RS18955	COG2059	Chromate
GKO36_RS18965	COG0655	NAD(P)H dehydrogenase (quinone) activity
GKO36_RS18970	COG0583	DNA-binding transcription factor activity
GKO36_RS19005	COG5444	nuclease activity
GKO36_RS19020	COG3878	Protein conserved in bacteria
GKO36_RS19025	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GKO36_RS19030	COG4464	protein tyrosine phosphatase activity
GKO36_RS19035	COG0489	protein tyrosine kinase activity
GKO36_RS19040	COG3944	biosynthesis protein
GKO36_RS19050	COG4715	Zinc finger, swim domain protein
GKO36_RS19055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GKO36_RS19060	COG0561	phosphatase activity
GKO36_RS19065	COG1349	DNA-binding transcription factor activity
GKO36_RS19070	COG0629	single-stranded DNA binding
GKO36_RS19095	COG0457	Tetratricopeptide repeat
GKO36_RS19100	COG4786	Flagellar basal body rod
GKO36_RS19105	COG4786	Flagellar basal body rod
GKO36_RS19110	COG1077	Cell shape determining protein MreB Mrl
GKO36_RS19115	COG1609	Transcriptional regulator
GKO36_RS19120	COG1846	Transcriptional regulator
GKO36_RS19125	COG2814	Major facilitator Superfamily
GKO36_RS19130	COG1953	Uracil, thiamine, allantoin
GKO36_RS19135	COG0477	Major facilitator Superfamily
GKO36_RS19140	COG1335	isochorismatase
GKO36_RS19145	COG0004	ammonium transporteR
GKO36_RS19150	COG0347	Belongs to the P(II) protein family
GKO36_RS19155	COG0772	Belongs to the SEDS family
GKO36_RS19160	COG0671	phosphoesterase, PA-phosphatase related
GKO36_RS19170	COG0739	heme binding
GKO36_RS19175	COG1247	-acetyltransferase
GKO36_RS19190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKO36_RS19200	COG0726	polysaccharide deacetylase
GKO36_RS19205	COG1959	2 iron, 2 sulfur cluster binding
GKO36_RS19220	COG0831	urea catabolic process
GKO36_RS19230	COG1994	Peptidase M50
GKO36_RS19235	COG0457	Tetratricopeptide repeat
GKO36_RS19245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GKO36_RS19255	COG2304	oxidoreductase activity
GKO36_RS19260	COG2304	oxidoreductase activity
GKO36_RS19265	COG2385	sporulation resulting in formation of a cellular spore
GKO36_RS19270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKO36_RS19280	COG4836	Membrane
GKO36_RS19350	COG0698	ribose 5-phosphate isomerase
GKO36_RS19355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKO36_RS19365	COG0009	L-threonylcarbamoyladenylate synthase
GKO36_RS19370	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GKO36_RS19390	COG2890	protein-(glutamine-N5) methyltransferase activity
GKO36_RS19395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKO36_RS19400	COG0346	lactoylglutathione lyase activity
GKO36_RS19405	COG0789	Transcriptional regulator
GKO36_RS19410	COG0679	Auxin Efflux Carrier
GKO36_RS19415	COG0281	malic enzyme
GKO36_RS19430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GKO36_RS19435	COG1494	fructose-1,6-bisphosphatase
GKO36_RS19440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKO36_RS19450	COG0191	fructose-bisphosphate aldolase activity
GKO36_RS19455	COG2204	response regulator
GKO36_RS19460	COG4821	SIS domain
GKO36_RS19475	COG2181	nitrate reductase activity
GKO36_RS19475	COG0247	lactate metabolic process
GKO36_RS19480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKO36_RS19495	COG1132	(ABC) transporter
GKO36_RS19500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKO36_RS19510	COG2181	nitrate reductase activity
GKO36_RS19515	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GKO36_RS19520	COG1140	nitrate reductase beta subunit
GKO36_RS19525	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKO36_RS19530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GKO36_RS19540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GKO36_RS19545	COG2223	nitrite transmembrane transporter activity
GKO36_RS19555	COG4506	Protein conserved in bacteria
GKO36_RS19560	COG0457	Tetratricopeptide repeat
GKO36_RS19600	COG0010	Belongs to the arginase family
GKO36_RS19605	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GKO36_RS19610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GKO36_RS19625	COG1994	Peptidase M50
GKO36_RS19630	COG1942	4-Oxalocrotonate Tautomerase
GKO36_RS19635	COG1846	Transcriptional regulator
GKO36_RS19645	COG0531	amino acid
GKO36_RS19650	COG3465	dGTPase activity
GKO36_RS19655	COG1078	dGTPase activity
GKO36_RS19670	COG1695	Transcriptional regulator
GKO36_RS19680	COG1131	(ABC) transporter
GKO36_RS19685	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GKO36_RS19715	COG0583	DNA-binding transcription factor activity
GKO36_RS19720	COG2855	membrane
GKO36_RS19725	COG0280	phosphate acetyltransferase
GKO36_RS19735	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS19740	COG0436	Aminotransferase
GKO36_RS19770	COG2814	Major facilitator Superfamily
GKO36_RS19775	COG2814	Major facilitator Superfamily
GKO36_RS19780	COG0833	amino acid
GKO36_RS19785	COG4187	Peptidase family M20/M25/M40
GKO36_RS19790	COG1012	belongs to the aldehyde dehydrogenase family
GKO36_RS19795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GKO36_RS19800	COG2205	protein histidine kinase activity
GKO36_RS19805	COG0745	RESPONSE REGULATOR receiver
GKO36_RS19820	COG1131	(ABC) transporter
GKO36_RS19825	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GKO36_RS19830	COG1091	dTDP-4-dehydrorhamnose reductase activity
GKO36_RS19835	COG1088	dTDP-glucose 4,6-dehydratase activity
GKO36_RS19840	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKO36_RS19845	COG3980	spore coat polysaccharide biosynthesis protein
GKO36_RS19850	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GKO36_RS19855	COG2089	acid synthase
GKO36_RS19860	COG0456	acetyltransferase
GKO36_RS19865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GKO36_RS19870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKO36_RS19875	COG0463	Glycosyl transferase, family 2
GKO36_RS19885	COG2363	Small membrane protein
GKO36_RS19890	COG2233	PERMEase
GKO36_RS19905	COG1216	Glycosyl transferase, family 2
GKO36_RS19920	COG1695	Transcriptional regulator
GKO36_RS19925	COG0351	phosphomethylpyrimidine kinase
GKO36_RS19935	COG1621	beta-fructofuranosidase activity
GKO36_RS19940	COG1263	PTS System
GKO36_RS19940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKO36_RS19945	COG3711	transcriptional antiterminator
GKO36_RS19955	COG1404	Belongs to the peptidase S8 family
GKO36_RS19960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKO36_RS19965	COG0778	Nitroreductase
GKO36_RS19970	COG0772	Belongs to the SEDS family
GKO36_RS19975	COG0454	-acetyltransferase
GKO36_RS19995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GKO36_RS20000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GKO36_RS20005	COG2261	transglycosylase associated protein
GKO36_RS20010	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GKO36_RS20015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKO36_RS20020	COG2246	polysaccharide biosynthetic process
GKO36_RS20025	COG1309	transcriptional regulator
GKO36_RS20045	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GKO36_RS20050	COG2837	iron assimilation
GKO36_RS20055	COG2822	iron ion transport
GKO36_RS20070	COG0583	DNA-binding transcription factor activity
GKO36_RS20080	COG1346	cytolysis
GKO36_RS20085	COG4895	conserved protein (DUF2196)
GKO36_RS20090	COG0789	Transcriptional regulator
GKO36_RS20100	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GKO36_RS20105	COG0346	lactoylglutathione lyase activity
GKO36_RS20110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKO36_RS20115	COG1404	Belongs to the peptidase S8 family
GKO36_RS20120	COG1442	glycosyl transferase family 8
GKO36_RS20125	COG1846	Transcriptional regulator
GKO36_RS20130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKO36_RS20135	COG2357	RelA SpoT domain protein
GKO36_RS20140	COG1575	Belongs to the MenA family. Type 1 subfamily
GKO36_RS20155	COG1696	Membrane protein involved in D-alanine export
GKO36_RS20165	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKO36_RS20170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GKO36_RS20175	COG1486	melibiose metabolic process
GKO36_RS20180	COG1447	Phosphotransferase system cellobiose-specific component IIA
GKO36_RS20185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKO36_RS20190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKO36_RS20195	COG3711	transcriptional antiterminator
GKO36_RS20195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKO36_RS20205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKO36_RS20210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKO36_RS20220	COG0640	Transcriptional regulator
GKO36_RS20225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GKO36_RS20230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKO36_RS20235	COG1447	Phosphotransferase system cellobiose-specific component IIA
GKO36_RS20240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKO36_RS20245	COG2723	6-phospho-beta-galactosidase activity
GKO36_RS20250	COG1940	carbohydrate kinase activity
GKO36_RS20255	COG1482	cell wall glycoprotein biosynthetic process
GKO36_RS20265	COG0753	catalase activity
GKO36_RS20270	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GKO36_RS20275	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GKO36_RS20280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GKO36_RS20285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GKO36_RS20290	COG4988	ABC transporter
GKO36_RS20295	COG1294	oxidase, subunit
GKO36_RS20300	COG1271	oxidase subunit
GKO36_RS20305	COG3493	citrate carrier protein
GKO36_RS20310	COG0726	polysaccharide deacetylase
GKO36_RS20315	COG3842	ATPase activity
GKO36_RS20320	COG2508	Transcriptional regulator
GKO36_RS20325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKO36_RS20335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKO36_RS20350	COG4894	glucomannan catabolic process
GKO36_RS20355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GKO36_RS20360	COG0500	methyltransferase
GKO36_RS20365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKO36_RS20385	COG0693	protein deglycase activity
GKO36_RS20385	COG0753	catalase activity
GKO36_RS20390	COG2851	Citrate transporter
GKO36_RS20395	COG2273	Hydrolase Family 16
GKO36_RS20400	COG3711	transcriptional antiterminator
GKO36_RS20405	COG2270	Major facilitator Superfamily
GKO36_RS20410	COG0513	Belongs to the DEAD box helicase family
GKO36_RS20455	COG3209	COG3209 Rhs family protein
GKO36_RS20465	COG0697	spore germination
GKO36_RS20470	COG0589	response to stress
GKO36_RS20480	COG0494	nUDIX hydrolase
GKO36_RS20485	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GKO36_RS20490	COG3507	Belongs to the glycosyl hydrolase 43 family
GKO36_RS20515	COG0010	Belongs to the arginase family
GKO36_RS20520	COG0833	amino acid
GKO36_RS20525	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GKO36_RS20530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKO36_RS20540	COG2390	Transcriptional regulator
GKO36_RS20545	COG0561	phosphatase activity
GKO36_RS20575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GKO36_RS20580	COG5294	Protein conserved in bacteria
GKO36_RS20585	COG0577	efflux transmembrane transporter activity
GKO36_RS20590	COG1136	(ABC) transporter
GKO36_RS20595	COG2205	protein histidine kinase activity
GKO36_RS20600	COG0745	RESPONSE REGULATOR receiver
GKO36_RS20605	COG2205	protein histidine kinase activity
GKO36_RS20610	COG0745	RESPONSE REGULATOR receiver
GKO36_RS20635	COG0745	RESPONSE REGULATOR receiver
GKO36_RS20665	COG1082	Xylose isomerase domain protein TIM barrel
GKO36_RS20675	COG2814	Major facilitator Superfamily
GKO36_RS20705	COG1349	DNA-binding transcription factor activity
GKO36_RS20710	COG0667	Aldo Keto reductase
GKO36_RS20715	COG2814	Major facilitator Superfamily
GKO36_RS20725	COG1028	Short-chain dehydrogenase reductase Sdr
GKO36_RS20730	COG2197	response regulator
GKO36_RS20735	COG4585	Histidine kinase
GKO36_RS20740	COG3239	Fatty acid desaturase
GKO36_RS20745	COG1309	transcriptional regulator
GKO36_RS20750	COG1012	belongs to the aldehyde dehydrogenase family
GKO36_RS20755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GKO36_RS20765	COG0640	Transcriptional regulator
GKO36_RS20775	COG1714	RDD family
GKO36_RS20785	COG0450	alkyl hydroperoxide reductase
GKO36_RS20790	COG3634	alkyl hydroperoxide reductase activity
GKO36_RS20795	COG3177	Filamentation induced by cAMP protein fic
GKO36_RS20800	COG1113	amino acid transport
GKO36_RS20810	COG2080	2 iron, 2 sulfur cluster binding
GKO36_RS20825	COG2068	MobA-Related Protein
GKO36_RS20885	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GKO36_RS20890	COG0667	Aldo Keto reductase
GKO36_RS20895	COG0456	acetyltransferase
GKO36_RS20900	COG0457	Tetratricopeptide repeat
GKO36_RS20905	COG0010	Belongs to the arginase family
GKO36_RS20910	COG0833	amino acid
GKO36_RS20915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GKO36_RS20920	COG3829	transcription factor binding
GKO36_RS20930	COG0488	(ABC) transporter
GKO36_RS20945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GKO36_RS20950	COG5002	protein histidine kinase activity
GKO36_RS20950	COG3850	Histidine kinase
GKO36_RS20955	COG0745	RESPONSE REGULATOR receiver
GKO36_RS20965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKO36_RS20970	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GKO36_RS20975	COG4853	Protein conserved in bacteria
GKO36_RS20980	COG4863	YycH protein
GKO36_RS20985	COG5002	protein histidine kinase activity
GKO36_RS20990	COG0745	RESPONSE REGULATOR receiver
GKO36_RS21020	COG0346	lactoylglutathione lyase activity
GKO36_RS21025	COG0305	Participates in initiation and elongation during chromosome replication
GKO36_RS21040	COG3093	addiction module antidote protein HigA
GKO36_RS21045	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKO36_RS21050	COG0297	glycogen (starch) synthase activity
GKO36_RS21060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GKO36_RS21065	COG0438	transferase activity, transferring glycosyl groups
GKO36_RS21075	COG2112	serine threonine protein kinase
GKO36_RS21085	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GKO36_RS21090	COG4241	membrane
GKO36_RS21100	COG5577	PFAM Coat F domain
GKO36_RS21105	COG1733	regulation of RNA biosynthetic process
GKO36_RS21115	COG0697	spore germination
GKO36_RS21120	COG1621	beta-fructofuranosidase activity
GKO36_RS21125	COG1621	beta-fructofuranosidase activity
GKO36_RS21130	COG1802	Transcriptional regulator
GKO36_RS21135	COG2318	DinB family
GKO36_RS21140	COG2211	Major facilitator Superfamily
GKO36_RS21145	COG0697	spore germination
GKO36_RS21155	COG0778	Nitroreductase
GKO36_RS21160	COG1846	Transcriptional regulator
GKO36_RS21165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKO36_RS21170	COG1846	Transcriptional regulator
GKO36_RS21175	COG2153	protein acetylation
GKO36_RS21185	COG0546	phosphoglycolate phosphatase activity
GKO36_RS21215	COG1404	Belongs to the peptidase S8 family
GKO36_RS21225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKO36_RS21230	COG0697	spore germination
GKO36_RS21235	COG1331	Highly conserved protein containing a thioredoxin domain
GKO36_RS21240	COG1266	CAAX protease self-immunity
GKO36_RS21245	COG2814	Major facilitator Superfamily
GKO36_RS21245	COG0477	Major facilitator Superfamily
GKO36_RS21250	COG0346	lactoylglutathione lyase activity
GKO36_RS21255	COG1609	Transcriptional regulator
GKO36_RS21265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKO36_RS21270	COG2169	Transcriptional regulator
GKO36_RS21280	COG0629	single-stranded DNA binding
GKO36_RS21290	COG0012	GTP binding
GKO36_RS21295	COG0243	molybdopterin cofactor binding
GKO36_RS21300	COG4481	Protein conserved in bacteria
GKO36_RS21305	COG3949	Membrane
GKO36_RS21320	COG1475	DNA binding
GKO36_RS21325	COG1192	Involved in chromosome partitioning
GKO36_RS21350	COG1847	R3H domain protein
GKO36_RS21355	COG0706	membrane insertase activity