locus-tag	class	description
H4K32_RS00015	COG0194	GDP metabolic process
H4K32_RS00025	COG1561	YicC-like family, N-terminal region
H4K32_RS00030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H4K32_RS00040	COG1648	precorrin-2 dehydrogenase activity
H4K32_RS00045	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
H4K32_RS00050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H4K32_RS00065	COG0306	phosphate transporter
H4K32_RS00075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H4K32_RS00080	COG0284	orotidine-5'-phosphate decarboxylase activity
H4K32_RS00095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H4K32_RS00100	COG0505	Belongs to the CarA family
H4K32_RS00105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H4K32_RS00115	COG2233	PERMEase
H4K32_RS00125	COG0564	pseudouridine synthase activity
H4K32_RS00135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H4K32_RS00140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H4K32_RS00145	COG3599	regulation of cell shape
H4K32_RS00150	COG2302	S4 RNA-binding domain
H4K32_RS00155	COG0762	integral membrane protein
H4K32_RS00165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H4K32_RS00175	COG1873	PFAM PRC-barrel domain
H4K32_RS00180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H4K32_RS00185	COG1119	ATPase activity
H4K32_RS00190	COG1191	sigma factor activity
H4K32_RS00195	COG1191	sigma factor activity
H4K32_RS00205	COG1404	Belongs to the peptidase S8 family
H4K32_RS00205	COG4412	M6 family metalloprotease domain protein
H4K32_RS00210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H4K32_RS00215	COG0849	cell division
H4K32_RS00220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H4K32_RS00235	COG0772	Belongs to the SEDS family
H4K32_RS00255	COG0768	penicillin binding
H4K32_RS00265	COG4839	cell division protein FtsL
H4K32_RS00285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H4K32_RS00305	COG1399	metal-binding, possibly nucleic acid-binding protein
H4K32_RS00315	COG3480	Lon protease (S16) C-terminal proteolytic domain
H4K32_RS00320	COG1752	Esterase of the alpha-beta hydrolase superfamily
H4K32_RS00325	COG3314	Sporulation integral membrane protein YlbJ
H4K32_RS00335	COG0742	ribosomal rna small subunit methyltransferase
H4K32_RS00350	COG3679	Belongs to the UPF0342 family
H4K32_RS00365	COG2340	Cysteine-rich secretory protein family
H4K32_RS00370	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H4K32_RS00380	COG3336	cytochrome c oxidase
H4K32_RS00385	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H4K32_RS00390	COG1845	cytochrome c oxidase, subunit III
H4K32_RS00395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H4K32_RS00400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H4K32_RS00400	COG2010	Cytochrome c
H4K32_RS00415	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H4K32_RS00420	COG0772	Belongs to the SEDS family
H4K32_RS00430	COG2066	Belongs to the glutaminase family
H4K32_RS00435	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H4K32_RS00440	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H4K32_RS00450	COG4896	Protein conserved in bacteria
H4K32_RS00485	COG3227	Zinc metalloprotease (Elastase)
H4K32_RS00495	COG0483	inositol monophosphate 1-phosphatase activity
H4K32_RS00515	COG1982	Orn Lys Arg decarboxylase major
H4K32_RS00530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H4K32_RS00535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H4K32_RS00540	COG0508	dehydrogenase complex catalyzes the overall conversion of
H4K32_RS00545	COG0022	dehydrogenase e1 component
H4K32_RS00550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H4K32_RS00555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H4K32_RS00560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS00560	COG4221	oxidoreductase activity
H4K32_RS00560	COG3321	synthase
H4K32_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS00565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS00565	COG0300	oxidoreductase activity
H4K32_RS00565	COG3321	synthase
H4K32_RS00565	COG4221	oxidoreductase activity
H4K32_RS00570	COG0300	oxidoreductase activity
H4K32_RS00570	COG4221	oxidoreductase activity
H4K32_RS00570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS00570	COG3321	synthase
H4K32_RS00575	COG0300	oxidoreductase activity
H4K32_RS00575	COG3321	synthase
H4K32_RS00575	COG4221	oxidoreductase activity
H4K32_RS00575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS00580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS00580	COG4221	oxidoreductase activity
H4K32_RS00580	COG3321	synthase
H4K32_RS00580	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS00585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS00585	COG3321	synthase
H4K32_RS00585	COG4221	oxidoreductase activity
H4K32_RS00585	COG0300	oxidoreductase activity
H4K32_RS00590	COG3321	synthase
H4K32_RS00590	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS00590	COG4221	oxidoreductase activity
H4K32_RS00590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS00600	COG0497	DNA recombination
H4K32_RS00610	COG0242	peptide deformylase activity
H4K32_RS00615	COG0561	phosphatase activity
H4K32_RS00625	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H4K32_RS00635	COG0569	domain protein
H4K32_RS00640	COG2105	PFAM AIG2 family protein
H4K32_RS00640	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H4K32_RS00645	COG3852	Histidine kinase
H4K32_RS00650	COG2002	toxin-antitoxin pair type II binding
H4K32_RS00655	COG1077	Cell shape determining protein MreB Mrl
H4K32_RS00665	COG2309	aminopeptidase activity
H4K32_RS00670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H4K32_RS00675	COG0488	(ABC) transporter
H4K32_RS00685	COG0681	Belongs to the peptidase S26 family
H4K32_RS00690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H4K32_RS00690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H4K32_RS00690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H4K32_RS00695	COG1105	Belongs to the carbohydrate kinase PfkB family
H4K32_RS00700	COG1349	DNA-binding transcription factor activity
H4K32_RS00705	COG0577	efflux transmembrane transporter activity
H4K32_RS00710	COG1136	(ABC) transporter
H4K32_RS00715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H4K32_RS00725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H4K32_RS00730	COG0314	molybdopterin synthase activity
H4K32_RS00735	COG1763	Mo-molybdopterin cofactor biosynthetic process
H4K32_RS00740	COG0303	'Molybdopterin
H4K32_RS00745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H4K32_RS00765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H4K32_RS00770	COG0668	transmembrane transport
H4K32_RS00790	COG0716	FMN binding
H4K32_RS00800	COG0716	FMN binding
H4K32_RS00805	COG0583	DNA-binding transcription factor activity
H4K32_RS00810	COG0517	IMP dehydrogenase activity
H4K32_RS00820	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H4K32_RS00825	COG4703	Protein of unknown function (DUF1797)
H4K32_RS00830	COG2200	EAL domain
H4K32_RS00840	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS00845	COG1408	metallophosphoesterase
H4K32_RS00850	COG1376	ErfK ybiS ycfS ynhG family protein
H4K32_RS00855	COG2814	Major facilitator Superfamily
H4K32_RS00865	COG0835	chemotaxis
H4K32_RS00865	COG0784	Response regulator, receiver
H4K32_RS00875	COG0436	Aminotransferase
H4K32_RS00880	COG4191	Histidine kinase
H4K32_RS00885	COG0768	penicillin binding
H4K32_RS00890	COG2340	Cysteine-rich secretory protein family
H4K32_RS00895	COG2084	Dehydrogenase
H4K32_RS00900	COG0840	transmembrane signaling receptor activity
H4K32_RS00905	COG1533	DNA photolyase activity
H4K32_RS00915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H4K32_RS00920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H4K32_RS00925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H4K32_RS00925	COG1263	PTS System
H4K32_RS00925	COG2190	(PTS) system
H4K32_RS00930	COG3711	transcriptional antiterminator
H4K32_RS00935	COG1609	Transcriptional regulator
H4K32_RS00940	COG0006	proline dipeptidase activity
H4K32_RS00945	COG2217	Heavy metal translocating P-type atpase
H4K32_RS00950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H4K32_RS00955	COG2244	polysaccharide biosynthetic process
H4K32_RS00960	COG3773	Cell wall hydrolase
H4K32_RS00970	COG4873	Protein conserved in bacteria
H4K32_RS00985	COG0602	queuosine metabolic process
H4K32_RS00990	COG0720	synthase
H4K32_RS01005	COG3949	Membrane
H4K32_RS01010	COG0542	response to heat
H4K32_RS01015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H4K32_RS01020	COG1360	Flagellar Motor Protein
H4K32_RS01025	COG1846	Transcriptional regulator
H4K32_RS01030	COG3852	Histidine kinase
H4K32_RS01060	COG0436	Aminotransferase
H4K32_RS01065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H4K32_RS01080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H4K32_RS01085	COG5002	protein histidine kinase activity
H4K32_RS01090	COG3594	Acyltransferase
H4K32_RS01100	COG2323	membrane
H4K32_RS01105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H4K32_RS01130	COG1191	sigma factor activity
H4K32_RS01135	COG0861	Integral membrane protein TerC family
H4K32_RS01140	COG0586	Pfam SNARE associated Golgi protein
H4K32_RS01145	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H4K32_RS01150	COG3285	dna ligase
H4K32_RS01150	COG1793	dna ligase
H4K32_RS01155	COG0726	polysaccharide deacetylase
H4K32_RS01160	COG1846	Transcriptional regulator
H4K32_RS01175	COG0789	Transcriptional regulator
H4K32_RS01180	COG2239	Acts as a magnesium transporter
H4K32_RS01190	COG3858	chitin binding
H4K32_RS01190	COG1388	LysM domain
H4K32_RS01195	COG4721	ABC-type cobalt transport system, permease component
H4K32_RS01200	COG1122	ATPase activity
H4K32_RS01205	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H4K32_RS01210	COG1366	Belongs to the anti-sigma-factor antagonist family
H4K32_RS01215	COG1404	Belongs to the peptidase S8 family
H4K32_RS01225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H4K32_RS01230	COG2814	Major facilitator Superfamily
H4K32_RS01240	COG0463	Glycosyl transferase, family 2
H4K32_RS01240	COG0457	Tetratricopeptide repeat
H4K32_RS01255	COG1764	response to oxidative stress
H4K32_RS01260	COG1846	Transcriptional regulator
H4K32_RS01265	COG1764	response to oxidative stress
H4K32_RS01275	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H4K32_RS01280	COG0788	formyltetrahydrofolate deformylase activity
H4K32_RS01285	COG2076	Multidrug Resistance protein
H4K32_RS01290	COG2076	Multidrug Resistance protein
H4K32_RS01295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H4K32_RS01300	COG1607	acyl-coa hydrolase
H4K32_RS01305	COG1834	amidinotransferase
H4K32_RS01310	COG2706	6-phosphogluconolactonase activity
H4K32_RS01315	COG4608	Belongs to the ABC transporter superfamily
H4K32_RS01320	COG0791	NLP P60 protein
H4K32_RS01325	COG4948	Mandelate Racemase Muconate Lactonizing
H4K32_RS01330	COG1619	proteins homologs of microcin C7 resistance protein MccF
H4K32_RS01335	COG4166	transmembrane transport
H4K32_RS01340	COG0444	Belongs to the ABC transporter superfamily
H4K32_RS01345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H4K32_RS01350	COG0601	transmembrane transport
H4K32_RS01355	COG2362	D-Aminopeptidase
H4K32_RS01360	COG0477	Major facilitator Superfamily
H4K32_RS01365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H4K32_RS01375	COG0463	Glycosyl transferase, family 2
H4K32_RS01380	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H4K32_RS01385	COG0346	lactoylglutathione lyase activity
H4K32_RS01390	COG0531	amino acid
H4K32_RS01395	COG1392	Phosphate transport regulator
H4K32_RS01400	COG0306	phosphate transporter
H4K32_RS01415	COG5632	N-Acetylmuramoyl-L-alanine amidase
H4K32_RS01415	COG3409	Peptidoglycan-binding domain 1 protein
H4K32_RS01455	COG3778	Protein conserved in bacteria
H4K32_RS01460	COG3299	homolog of phage Mu protein gp47
H4K32_RS01465	COG3628	GPW Gp25 family protein
H4K32_RS01475	COG4193	domain, Protein
H4K32_RS01480	COG1652	LysM domain
H4K32_RS01485	COG5412	phage tail tape measure protein
H4K32_RS01485	COG3953	SLT domain
H4K32_RS01485	COG5412	phage tail tape measure protein
H4K32_RS01485	COG3953	SLT domain
H4K32_RS01485	COG3953	SLT domain
H4K32_RS01485	COG5412	phage tail tape measure protein
H4K32_RS01535	COG4653	Phage capsid family
H4K32_RS01540	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H4K32_RS01545	COG5518	Phage portal protein
H4K32_RS01550	COG1783	phage Terminase large subunit
H4K32_RS01555	COG5484	DNA packaging
H4K32_RS01555	COG3728	DNA packaging
H4K32_RS01560	COG1595	DNA-templated transcription, initiation
H4K32_RS01580	COG1484	DNA-dependent DNA replication
H4K32_RS01585	COG1522	sequence-specific DNA binding
H4K32_RS01595	COG1396	sequence-specific DNA binding
H4K32_RS01600	COG2856	Zn peptidase
H4K32_RS01610	COG4195	phage-related replication protein
H4K32_RS01620	COG1388	LysM domain
H4K32_RS01620	COG3409	Peptidoglycan-binding domain 1 protein
H4K32_RS01620	COG5632	N-Acetylmuramoyl-L-alanine amidase
H4K32_RS01630	COG0457	Tetratricopeptide repeat
H4K32_RS01635	COG2318	DinB family
H4K32_RS01640	COG0730	response to heat
H4K32_RS01645	COG2721	sulfolactate sulfo-lyase activity
H4K32_RS01650	COG0246	Mannitol dehydrogenase
H4K32_RS01655	COG1609	Transcriptional regulator
H4K32_RS01660	COG2211	Major facilitator Superfamily
H4K32_RS01670	COG1252	NADH dehydrogenase
H4K32_RS01680	COG4297	protein containing double-stranded beta helix domain
H4K32_RS01685	COG0697	spore germination
H4K32_RS01690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H4K32_RS01695	COG0390	transport system, permease component
H4K32_RS01700	COG1587	Uroporphyrinogen-III synthase
H4K32_RS01710	COG1819	glycosyl
H4K32_RS01715	COG2124	cytochrome p450
H4K32_RS01720	COG2427	Protein of unknown function (DUF1641)
H4K32_RS01725	COG3383	formate dehydrogenase (NAD+) activity
H4K32_RS01735	COG2205	protein histidine kinase activity
H4K32_RS01745	COG1285	pathogenesis
H4K32_RS01760	COG1349	DNA-binding transcription factor activity
H4K32_RS01770	COG1447	Phosphotransferase system cellobiose-specific component IIA
H4K32_RS01775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H4K32_RS01775	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H4K32_RS01780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H4K32_RS01785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H4K32_RS01790	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H4K32_RS01800	COG1846	Transcriptional regulator
H4K32_RS01805	COG0477	Major facilitator Superfamily
H4K32_RS01810	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H4K32_RS01815	COG2367	Beta-lactamase
H4K32_RS01820	COG0346	lactoylglutathione lyase activity
H4K32_RS01865	COG3321	synthase
H4K32_RS01885	COG4221	oxidoreductase activity
H4K32_RS01885	COG3321	synthase
H4K32_RS01885	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS01885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS01920	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS01920	COG3321	synthase
H4K32_RS01920	COG4221	oxidoreductase activity
H4K32_RS01920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS01930	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS01930	COG0300	oxidoreductase activity
H4K32_RS01930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS01930	COG3321	synthase
H4K32_RS01930	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS01950	COG3321	synthase
H4K32_RS01950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS01950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS01950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS01950	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS01960	COG3321	synthase
H4K32_RS01960	COG4221	oxidoreductase activity
H4K32_RS01960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS01960	COG0300	oxidoreductase activity
H4K32_RS01965	COG4221	oxidoreductase activity
H4K32_RS01965	COG3321	synthase
H4K32_RS01965	COG0300	oxidoreductase activity
H4K32_RS01965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS01975	COG3321	synthase
H4K32_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS01975	COG0300	oxidoreductase activity
H4K32_RS01975	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS01980	COG0300	oxidoreductase activity
H4K32_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS01980	COG3321	synthase
H4K32_RS01980	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS01990	COG4221	oxidoreductase activity
H4K32_RS01990	COG3321	synthase
H4K32_RS01990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS01990	COG0300	oxidoreductase activity
H4K32_RS01995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS01995	COG3321	synthase
H4K32_RS01995	COG0300	oxidoreductase activity
H4K32_RS01995	COG4221	oxidoreductase activity
H4K32_RS02005	COG4221	oxidoreductase activity
H4K32_RS02005	COG3321	synthase
H4K32_RS02005	COG0300	oxidoreductase activity
H4K32_RS02005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02015	COG3321	synthase
H4K32_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02020	COG3321	synthase
H4K32_RS02020	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02020	COG4221	oxidoreductase activity
H4K32_RS02030	COG3321	synthase
H4K32_RS02030	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02030	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02030	COG0300	oxidoreductase activity
H4K32_RS02035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02035	COG4221	oxidoreductase activity
H4K32_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02035	COG3321	synthase
H4K32_RS02040	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02040	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02040	COG3321	synthase
H4K32_RS02040	COG0300	oxidoreductase activity
H4K32_RS02045	COG0300	oxidoreductase activity
H4K32_RS02045	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02045	COG3321	synthase
H4K32_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02050	COG0300	oxidoreductase activity
H4K32_RS02050	COG3321	synthase
H4K32_RS02050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02050	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02050	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02055	COG4221	oxidoreductase activity
H4K32_RS02055	COG3321	synthase
H4K32_RS02055	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02060	COG0300	oxidoreductase activity
H4K32_RS02060	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02060	COG3321	synthase
H4K32_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02075	COG0300	oxidoreductase activity
H4K32_RS02075	COG4221	oxidoreductase activity
H4K32_RS02075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02075	COG3321	synthase
H4K32_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02110	COG3321	synthase
H4K32_RS02110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02120	COG3321	synthase
H4K32_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02125	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02125	COG3321	synthase
H4K32_RS02125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02130	COG0300	oxidoreductase activity
H4K32_RS02130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02130	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02130	COG3321	synthase
H4K32_RS02130	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02135	COG4221	oxidoreductase activity
H4K32_RS02135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02135	COG3321	synthase
H4K32_RS02145	COG4221	oxidoreductase activity
H4K32_RS02145	COG3321	synthase
H4K32_RS02145	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02155	COG0300	oxidoreductase activity
H4K32_RS02155	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02155	COG3321	synthase
H4K32_RS02160	COG3321	synthase
H4K32_RS02160	COG0300	oxidoreductase activity
H4K32_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02160	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02165	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02165	COG3321	synthase
H4K32_RS02165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02165	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02165	COG0300	oxidoreductase activity
H4K32_RS02175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02175	COG4221	oxidoreductase activity
H4K32_RS02175	COG3321	synthase
H4K32_RS02175	COG0300	oxidoreductase activity
H4K32_RS02180	COG4221	oxidoreductase activity
H4K32_RS02180	COG3321	synthase
H4K32_RS02180	COG0300	oxidoreductase activity
H4K32_RS02180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02185	COG3321	synthase
H4K32_RS02185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02190	COG3321	synthase
H4K32_RS02190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02195	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02195	COG3321	synthase
H4K32_RS02210	COG3321	synthase
H4K32_RS02210	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H4K32_RS02210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H4K32_RS02210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02215	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02215	COG3321	synthase
H4K32_RS02220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02220	COG3321	synthase
H4K32_RS02220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02220	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02230	COG0300	oxidoreductase activity
H4K32_RS02230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02230	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02230	COG3321	synthase
H4K32_RS02230	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02235	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02235	COG4221	oxidoreductase activity
H4K32_RS02235	COG3321	synthase
H4K32_RS02240	COG3321	synthase
H4K32_RS02240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02240	COG0300	oxidoreductase activity
H4K32_RS02240	COG4221	oxidoreductase activity
H4K32_RS02245	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02245	COG3321	synthase
H4K32_RS02245	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02245	COG0300	oxidoreductase activity
H4K32_RS02245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02255	COG3321	synthase
H4K32_RS02255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02255	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02255	COG4221	oxidoreductase activity
H4K32_RS02270	COG4221	oxidoreductase activity
H4K32_RS02270	COG3321	synthase
H4K32_RS02270	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02275	COG3321	synthase
H4K32_RS02275	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02275	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02275	COG0300	oxidoreductase activity
H4K32_RS02290	COG3321	synthase
H4K32_RS02290	COG4221	oxidoreductase activity
H4K32_RS02290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02290	COG0300	oxidoreductase activity
H4K32_RS02295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02295	COG3321	synthase
H4K32_RS02295	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02300	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02300	COG3321	synthase
H4K32_RS02305	COG0300	oxidoreductase activity
H4K32_RS02305	COG3321	synthase
H4K32_RS02305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02305	COG4221	oxidoreductase activity
H4K32_RS02310	COG3321	synthase
H4K32_RS02310	COG0300	oxidoreductase activity
H4K32_RS02310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02310	COG4221	oxidoreductase activity
H4K32_RS02320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02320	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02320	COG3321	synthase
H4K32_RS02320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS02325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02325	COG4221	oxidoreductase activity
H4K32_RS02325	COG3321	synthase
H4K32_RS02325	COG0300	oxidoreductase activity
H4K32_RS02330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02330	COG0300	oxidoreductase activity
H4K32_RS02330	COG3321	synthase
H4K32_RS02330	COG4221	oxidoreductase activity
H4K32_RS02340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02340	COG3321	synthase
H4K32_RS02340	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02340	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02340	COG0300	oxidoreductase activity
H4K32_RS02345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02345	COG0300	oxidoreductase activity
H4K32_RS02345	COG3321	synthase
H4K32_RS02345	COG4221	oxidoreductase activity
H4K32_RS02350	COG3321	synthase
H4K32_RS02350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02350	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02350	COG0300	oxidoreductase activity
H4K32_RS02355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02355	COG3321	synthase
H4K32_RS02355	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02355	COG0300	oxidoreductase activity
H4K32_RS02355	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02360	COG4221	oxidoreductase activity
H4K32_RS02360	COG3321	synthase
H4K32_RS02360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02360	COG0300	oxidoreductase activity
H4K32_RS02365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02365	COG0300	oxidoreductase activity
H4K32_RS02365	COG3321	synthase
H4K32_RS02365	COG4221	oxidoreductase activity
H4K32_RS02385	COG0300	oxidoreductase activity
H4K32_RS02385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS02385	COG3321	synthase
H4K32_RS02385	COG4221	oxidoreductase activity
H4K32_RS02390	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02390	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02390	COG3321	synthase
H4K32_RS02390	COG0300	oxidoreductase activity
H4K32_RS02400	COG0300	oxidoreductase activity
H4K32_RS02400	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02400	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02400	COG3321	synthase
H4K32_RS02405	COG0300	oxidoreductase activity
H4K32_RS02405	COG3321	synthase
H4K32_RS02405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02405	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS02410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02410	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02410	COG4221	oxidoreductase activity
H4K32_RS02410	COG3321	synthase
H4K32_RS02415	COG4221	oxidoreductase activity
H4K32_RS02415	COG3321	synthase
H4K32_RS02415	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS02415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS02520	COG2070	2-Nitropropane dioxygenase
H4K32_RS02520	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H4K32_RS02525	COG2070	2-Nitropropane dioxygenase
H4K32_RS02525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H4K32_RS02545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H4K32_RS02575	COG0626	cystathionine gamma-synthase activity
H4K32_RS02580	COG0626	cystathionine gamma-synthase activity
H4K32_RS02585	COG2382	esterase
H4K32_RS02595	COG2153	protein acetylation
H4K32_RS02610	COG0210	DNA helicase
H4K32_RS02665	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H4K32_RS02670	COG0351	phosphomethylpyrimidine kinase
H4K32_RS02675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H4K32_RS02685	COG2104	thiamine diphosphate biosynthetic process
H4K32_RS02690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H4K32_RS02695	COG0352	thiamine-phosphate diphosphorylase activity
H4K32_RS02700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H4K32_RS02705	COG0569	domain protein
H4K32_RS02705	COG0475	glutathione-regulated potassium exporter activity
H4K32_RS02715	COG0564	pseudouridine synthase activity
H4K32_RS02720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H4K32_RS02725	COG2357	RelA SpoT domain protein
H4K32_RS02735	COG4116	CYTH
H4K32_RS02740	COG0741	lytic transglycosylase activity
H4K32_RS02745	COG2346	COG2346, Truncated hemoglobins
H4K32_RS02760	COG1164	Oligoendopeptidase f
H4K32_RS02765	COG4469	Competence protein
H4K32_RS02770	COG4862	establishment of competence for transformation
H4K32_RS02780	COG0861	Integral membrane protein TerC family
H4K32_RS02785	COG1393	Belongs to the ArsC family
H4K32_RS02790	COG0456	acetyltransferase
H4K32_RS02800	COG4608	Belongs to the ABC transporter superfamily
H4K32_RS02805	COG0444	Belongs to the ABC transporter superfamily
H4K32_RS02810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H4K32_RS02815	COG0601	transmembrane transport
H4K32_RS02820	COG4166	transmembrane transport
H4K32_RS02825	COG0180	Tryptophanyl-tRNA synthetase
H4K32_RS02835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H4K32_RS02840	COG0601	transmembrane transport
H4K32_RS02850	COG4608	Belongs to the ABC transporter superfamily
H4K32_RS02855	COG0444	Belongs to the ABC transporter superfamily
H4K32_RS02860	COG5504	Zn-dependent protease
H4K32_RS02865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H4K32_RS02870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H4K32_RS02885	COG1744	ABC transporter substrate-binding protein PnrA-like
H4K32_RS02895	COG2267	carboxylic ester hydrolase activity
H4K32_RS02910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H4K32_RS02915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H4K32_RS02920	COG0505	Belongs to the CarA family
H4K32_RS02925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H4K32_RS02935	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H4K32_RS02945	COG2271	Major facilitator Superfamily
H4K32_RS02950	COG0277	FAD linked oxidase domain protein
H4K32_RS02960	COG2151	metal-sulfur cluster biosynthetic enzyme
H4K32_RS02965	COG1073	alpha beta
H4K32_RS02970	COG0561	phosphatase activity
H4K32_RS02990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H4K32_RS02995	COG1307	EDD domain protein, DegV family
H4K32_RS03005	COG0840	transmembrane signaling receptor activity
H4K32_RS03015	COG2996	Protein conserved in bacteria
H4K32_RS03025	COG0646	methionine synthase
H4K32_RS03025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H4K32_RS03030	COG2153	protein acetylation
H4K32_RS03035	COG1357	PFAM Pentapeptide repeats (8 copies)
H4K32_RS03040	COG2318	DinB family
H4K32_RS03045	COG0673	inositol 2-dehydrogenase activity
H4K32_RS03050	COG1609	Transcriptional regulator
H4K32_RS03055	COG2207	Transcriptional regulator
H4K32_RS03055	COG1917	Cupin 2, conserved barrel domain protein
H4K32_RS03060	COG0534	Mate efflux family protein
H4K32_RS03065	COG1562	ergosterol biosynthetic process
H4K32_RS03070	COG0367	asparagine synthase
H4K32_RS03085	COG0179	Fumarylacetoacetate (FAA) hydrolase
H4K32_RS03125	COG1403	HNH endonuclease
H4K32_RS03130	COG0419	ATPase involved in DNA repair
H4K32_RS03135	COG0420	3'-5' exonuclease activity
H4K32_RS03150	COG2323	membrane
H4K32_RS03155	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H4K32_RS03165	COG2814	Major facilitator Superfamily
H4K32_RS03170	COG3180	Ammonia monooxygenase
H4K32_RS03175	COG1846	Transcriptional regulator
H4K32_RS03180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H4K32_RS03185	COG0681	Belongs to the peptidase S26 family
H4K32_RS03190	COG0398	Pfam SNARE associated Golgi protein
H4K32_RS03205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H4K32_RS03225	COG5646	InterPro IPR014922
H4K32_RS03235	COG4903	ComK protein
H4K32_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS03250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H4K32_RS03250	COG0723	plastoquinol--plastocyanin reductase activity
H4K32_RS03255	COG0840	transmembrane signaling receptor activity
H4K32_RS03260	COG1268	BioY protein
H4K32_RS03265	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS03270	COG0183	Belongs to the thiolase family
H4K32_RS03275	COG0406	alpha-ribazole phosphatase activity
H4K32_RS03280	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H4K32_RS03285	COG1404	Belongs to the peptidase S8 family
H4K32_RS03290	COG0501	Belongs to the peptidase M48B family
H4K32_RS03300	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS03305	COG0702	epimerase
H4K32_RS03310	COG0095	Lipoate-protein ligase
H4K32_RS03325	COG1301	dicarboxylic acid transport
H4K32_RS03330	COG1363	Peptidase, m42
H4K32_RS03340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H4K32_RS03345	COG1511	domain protein
H4K32_RS03350	COG1309	transcriptional regulator
H4K32_RS03370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H4K32_RS03375	COG2329	Antibiotic biosynthesis monooxygenase
H4K32_RS03380	COG3069	C4-dicarboxylate transmembrane transporter activity
H4K32_RS03385	COG1473	amidohydrolase
H4K32_RS03395	COG4473	ABC transporter
H4K32_RS03400	COG1131	(ABC) transporter
H4K32_RS03405	COG0537	adenosine 5'-monophosphoramidase activity
H4K32_RS03410	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H4K32_RS03425	COG4980	gas vesicle protein
H4K32_RS03460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H4K32_RS03475	COG4717	serine-type aminopeptidase activity
H4K32_RS03480	COG0420	3'-5' exonuclease activity
H4K32_RS03485	COG1668	transmembrane transport
H4K32_RS03490	COG4152	abc transporter atp-binding protein
H4K32_RS03500	COG1024	Enoyl-CoA hydratase
H4K32_RS03510	COG0490	domain, Protein
H4K32_RS03515	COG0475	glutathione-regulated potassium exporter activity
H4K32_RS03525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H4K32_RS03530	COG0561	phosphatase activity
H4K32_RS03535	COG4335	DNA alkylation repair
H4K32_RS03550	COG0189	ligase activity
H4K32_RS03555	COG0189	ligase activity
H4K32_RS03570	COG0702	epimerase
H4K32_RS03575	COG1132	(ABC) transporter
H4K32_RS03580	COG1132	(ABC) transporter
H4K32_RS03585	COG0589	response to stress
H4K32_RS03595	COG3226	Transcriptional regulator
H4K32_RS03600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H4K32_RS03605	COG0726	polysaccharide deacetylase
H4K32_RS03610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H4K32_RS03615	COG0668	transmembrane transport
H4K32_RS03625	COG0584	glycerophosphoryl diester phosphodiesterase
H4K32_RS03630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H4K32_RS03635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H4K32_RS03640	COG1253	flavin adenine dinucleotide binding
H4K32_RS03645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H4K32_RS03650	COG0436	Aminotransferase
H4K32_RS03655	COG0789	Transcriptional regulator
H4K32_RS03660	COG1253	flavin adenine dinucleotide binding
H4K32_RS03665	COG0204	Acyl-transferase
H4K32_RS03670	COG1595	DNA-templated transcription, initiation
H4K32_RS03685	COG0733	neurotransmitter:sodium symporter activity
H4K32_RS03690	COG0531	amino acid
H4K32_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS03700	COG0372	Belongs to the citrate synthase family
H4K32_RS03705	COG0583	DNA-binding transcription factor activity
H4K32_RS03710	COG1388	LysM domain
H4K32_RS03710	COG0791	NLP P60 protein
H4K32_RS03715	COG1785	Belongs to the alkaline phosphatase family
H4K32_RS03720	COG2719	SpoVR family
H4K32_RS03725	COG0668	transmembrane transport
H4K32_RS03730	COG1959	2 iron, 2 sulfur cluster binding
H4K32_RS03735	COG0791	NLP P60 protein
H4K32_RS03735	COG1388	LysM domain
H4K32_RS03750	COG0431	NADPH-dependent FMN reductase
H4K32_RS03765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H4K32_RS03770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H4K32_RS03780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H4K32_RS03785	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H4K32_RS03790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H4K32_RS03795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H4K32_RS03795	COG3153	acetyltransferase
H4K32_RS03800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H4K32_RS03805	COG0517	IMP dehydrogenase activity
H4K32_RS03815	COG0564	pseudouridine synthase activity
H4K32_RS03820	COG3764	Sortase (surface protein transpeptidase)
H4K32_RS03825	COG0737	Belongs to the 5'-nucleotidase family
H4K32_RS03825	COG1525	nuclease
H4K32_RS03825	COG4085	toxin activity
H4K32_RS03830	COG5577	PFAM Coat F domain
H4K32_RS03850	COG1823	symporter activity
H4K32_RS03855	COG3706	GGDEF domain
H4K32_RS03860	COG1464	Belongs to the NlpA lipoprotein family
H4K32_RS03865	COG1278	Cold shock
H4K32_RS03870	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H4K32_RS03875	COG1131	(ABC) transporter
H4K32_RS03880	COG1131	(ABC) transporter
H4K32_RS03885	COG1725	Transcriptional regulator
H4K32_RS03900	COG0655	NAD(P)H dehydrogenase (quinone) activity
H4K32_RS03905	COG2814	Major facilitator Superfamily
H4K32_RS03910	COG1566	PFAM secretion protein HlyD family protein
H4K32_RS03915	COG1846	Transcriptional regulator
H4K32_RS03925	COG2766	serine protein kinase
H4K32_RS03930	COG1664	Polymer-forming cytoskeletal
H4K32_RS03935	COG1664	Polymer-forming cytoskeletal
H4K32_RS03940	COG0789	Transcriptional regulator
H4K32_RS03945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H4K32_RS03955	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H4K32_RS03960	COG3382	B3 4 domain protein
H4K32_RS03970	COG1476	TRANSCRIPTIONal
H4K32_RS03990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H4K32_RS03995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H4K32_RS04000	COG1116	anion transmembrane transporter activity
H4K32_RS04010	COG0753	catalase activity
H4K32_RS04015	COG4608	Belongs to the ABC transporter superfamily
H4K32_RS04020	COG0444	Belongs to the ABC transporter superfamily
H4K32_RS04025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H4K32_RS04030	COG0601	transmembrane transport
H4K32_RS04035	COG0747	negative chemotaxis
H4K32_RS04045	COG0277	FAD linked oxidase domain protein
H4K32_RS04055	COG3340	Belongs to the peptidase S51 family
H4K32_RS04170	COG0735	belongs to the Fur family
H4K32_RS04175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H4K32_RS04185	COG4129	membrane
H4K32_RS04190	COG1132	(ABC) transporter
H4K32_RS04210	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS04220	COG1194	a g-specific adenine glycosylase
H4K32_RS04225	COG1988	membrane-bound metal-dependent
H4K32_RS04230	COG4485	Bacterial membrane protein, YfhO
H4K32_RS04235	COG0463	Glycosyl transferase, family 2
H4K32_RS04240	COG0596	Alpha beta hydrolase
H4K32_RS04245	COG5658	integral membrane protein
H4K32_RS04250	COG3103	Sh3 type 3 domain protein
H4K32_RS04265	COG3591	Belongs to the peptidase S1B family
H4K32_RS04275	COG2814	Major facilitator Superfamily
H4K32_RS04290	COG1090	epimerase
H4K32_RS04305	COG0778	Nitroreductase
H4K32_RS04310	COG0384	phenazine biosynthesis protein PhzF
H4K32_RS04315	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H4K32_RS04315	COG0392	lysyltransferase activity
H4K32_RS04320	COG1846	Transcriptional regulator
H4K32_RS04325	COG2814	Major facilitator Superfamily
H4K32_RS04330	COG2318	DinB family
H4K32_RS04335	COG2732	(Barnase) inhibitor
H4K32_RS04340	COG0574	Belongs to the PEP-utilizing enzyme family
H4K32_RS04340	COG3848	Pyruvate phosphate dikinase
H4K32_RS04345	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
H4K32_RS04350	COG2249	NAD(P)H dehydrogenase (quinone) activity
H4K32_RS04355	COG1695	Transcriptional regulator
H4K32_RS04365	COG2514	catechol 2,3-dioxygenase activity
H4K32_RS04370	COG2259	Doxx family
H4K32_RS04375	COG1132	(ABC) transporter
H4K32_RS04380	COG1132	(ABC) transporter
H4K32_RS04385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H4K32_RS04385	COG1263	PTS System
H4K32_RS04390	COG1737	Transcriptional regulator
H4K32_RS04395	COG1486	melibiose metabolic process
H4K32_RS04405	COG3284	Transcriptional regulator
H4K32_RS04410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H4K32_RS04415	COG0508	dehydrogenase complex catalyzes the overall conversion of
H4K32_RS04420	COG0022	dehydrogenase e1 component
H4K32_RS04425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H4K32_RS04430	COG4637	Psort location Cytoplasmic, score
H4K32_RS04435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H4K32_RS04445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H4K32_RS04450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H4K32_RS04455	COG0598	Magnesium transport protein CorA
H4K32_RS04465	COG2084	Dehydrogenase
H4K32_RS04470	COG0726	polysaccharide deacetylase
H4K32_RS04480	COG0535	radical SAM domain protein
H4K32_RS04485	COG0668	transmembrane transport
H4K32_RS04495	COG0387	Pfam Sodium calcium exchanger
H4K32_RS04500	COG0477	Major facilitator Superfamily
H4K32_RS04505	COG1295	ribonuclease BN
H4K32_RS04510	COG4980	gas vesicle protein
H4K32_RS04515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H4K32_RS04525	COG2814	Major facilitator Superfamily
H4K32_RS04540	COG1609	Transcriptional regulator
H4K32_RS04545	COG0693	protein deglycase activity
H4K32_RS04550	COG0737	Belongs to the 5'-nucleotidase family
H4K32_RS04565	COG0778	Nitroreductase
H4K32_RS04570	COG2188	Transcriptional regulator
H4K32_RS04575	COG0366	Alpha amylase catalytic
H4K32_RS04580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H4K32_RS04580	COG1263	PTS System
H4K32_RS04595	COG0071	Belongs to the small heat shock protein (HSP20) family
H4K32_RS04605	COG1368	sulfuric ester hydrolase activity
H4K32_RS04615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H4K32_RS04615	COG1263	PTS System
H4K32_RS04620	COG0024	Methionine aminopeptidase
H4K32_RS04640	COG2258	MOSC domain
H4K32_RS04650	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H4K32_RS04655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4K32_RS04660	COG2851	Citrate transporter
H4K32_RS04665	COG3181	Tripartite tricarboxylate transporter family receptor
H4K32_RS04670	COG4565	transcriptional regulatory protein
H4K32_RS04675	COG3290	protein histidine kinase activity
H4K32_RS04690	COG0471	metal ion transport
H4K32_RS04695	COG3866	Pectate lyase
H4K32_RS04710	COG2130	NADP-dependent
H4K32_RS04715	COG0456	acetyltransferase
H4K32_RS04720	COG0513	Belongs to the DEAD box helicase family
H4K32_RS04725	COG0488	(ABC) transporter
H4K32_RS04730	COG2814	Major facilitator Superfamily
H4K32_RS04735	COG0789	Transcriptional regulator
H4K32_RS04740	COG0488	(ABC) transporter
H4K32_RS04745	COG0463	Glycosyl transferase, family 2
H4K32_RS04745	COG0457	Tetratricopeptide repeat
H4K32_RS04750	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS04755	COG0840	transmembrane signaling receptor activity
H4K32_RS04760	COG1012	belongs to the aldehyde dehydrogenase family
H4K32_RS04765	COG0531	amino acid
H4K32_RS04770	COG2223	nitrite transmembrane transporter activity
H4K32_RS04775	COG1442	glycosyl transferase family 8
H4K32_RS04780	COG1216	Glycosyl transferase, family 2
H4K32_RS04785	COG1442	glycosyl transferase family 8
H4K32_RS04790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS04795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H4K32_RS04800	COG1368	sulfuric ester hydrolase activity
H4K32_RS04805	COG2124	cytochrome p450
H4K32_RS04805	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H4K32_RS04815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H4K32_RS04820	COG1846	Transcriptional regulator
H4K32_RS04830	COG0670	Belongs to the BI1 family
H4K32_RS04835	COG0196	riboflavin kinase activity
H4K32_RS04840	COG5583	Uncharacterized small protein (DUF2292)
H4K32_RS04845	COG1366	Belongs to the anti-sigma-factor antagonist family
H4K32_RS04850	COG0346	lactoylglutathione lyase activity
H4K32_RS04855	COG2329	Antibiotic biosynthesis monooxygenase
H4K32_RS04860	COG2323	membrane
H4K32_RS04870	COG0454	-acetyltransferase
H4K32_RS04875	COG3546	catalase activity
H4K32_RS04945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H4K32_RS04950	COG1597	lipid kinase activity
H4K32_RS04955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H4K32_RS04960	COG1309	transcriptional regulator
H4K32_RS04980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H4K32_RS04985	COG1285	pathogenesis
H4K32_RS04990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H4K32_RS04995	COG4851	CamS sex pheromone cAM373 precursor
H4K32_RS05005	COG0210	DNA helicase
H4K32_RS05015	COG0069	glutamate synthase activity
H4K32_RS05020	COG4496	protein, YerC YecD
H4K32_RS05025	COG1470	cell adhesion involved in biofilm formation
H4K32_RS05030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H4K32_RS05040	COG0151	Belongs to the GarS family
H4K32_RS05045	COG0138	bifunctional purine biosynthesis protein purh
H4K32_RS05050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H4K32_RS05060	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H4K32_RS05075	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H4K32_RS05080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H4K32_RS05085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H4K32_RS05090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H4K32_RS05095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H4K32_RS05115	COG3064	Membrane
H4K32_RS05120	COG2252	PERMEase
H4K32_RS05140	COG1305	Transglutaminase-like
H4K32_RS05145	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
H4K32_RS05150	COG0714	Associated with various cellular activities
H4K32_RS05155	COG1113	amino acid transport
H4K32_RS05160	COG2132	Multicopper oxidase
H4K32_RS05175	COG0823	Involved in the tonB-independent uptake of proteins
H4K32_RS05180	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H4K32_RS05185	COG1063	alcohol dehydrogenase
H4K32_RS05190	COG1595	DNA-templated transcription, initiation
H4K32_RS05200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H4K32_RS05200	COG2755	lipolytic protein G-D-S-L family
H4K32_RS05205	COG4260	virion core protein, lumpy skin disease virus
H4K32_RS05210	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H4K32_RS05215	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H4K32_RS05220	COG1842	Phage shock protein A
H4K32_RS05230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H4K32_RS05235	COG2211	Major facilitator Superfamily
H4K32_RS05240	COG1063	alcohol dehydrogenase
H4K32_RS05245	COG0457	Tetratricopeptide repeat
H4K32_RS05265	COG1266	CAAX protease self-immunity
H4K32_RS05275	COG0805	protein transport
H4K32_RS05280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H4K32_RS05295	COG0488	(ABC) transporter
H4K32_RS05300	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H4K32_RS05305	COG0456	acetyltransferase
H4K32_RS05310	COG1214	PFAM Peptidase M22, glycoprotease
H4K32_RS05315	COG0802	atpase or kinase
H4K32_RS05320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H4K32_RS05360	COG2814	Major facilitator Superfamily
H4K32_RS05365	COG0604	alcohol dehydrogenase
H4K32_RS05370	COG3832	glyoxalase III activity
H4K32_RS05380	COG0531	amino acid
H4K32_RS05385	COG1309	transcriptional regulator
H4K32_RS05390	COG2076	Multidrug Resistance protein
H4K32_RS05395	COG2076	Multidrug Resistance protein
H4K32_RS05400	COG2807	transmembrane transport
H4K32_RS05405	COG2186	Transcriptional regulator
H4K32_RS05410	COG2188	Transcriptional regulator
H4K32_RS05415	COG2814	Major facilitator Superfamily
H4K32_RS05420	COG1388	LysM domain
H4K32_RS05430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H4K32_RS05445	COG1819	glycosyl
H4K32_RS05450	COG1802	Transcriptional regulator
H4K32_RS05470	COG2226	methyltransferase
H4K32_RS05475	COG1051	belongs to the nudix hydrolase family
H4K32_RS05480	COG0697	spore germination
H4K32_RS05485	COG0789	Transcriptional regulator
H4K32_RS05485	COG4978	Transcriptional regulator
H4K32_RS05490	COG0456	acetyltransferase
H4K32_RS05495	COG0730	response to heat
H4K32_RS05505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H4K32_RS05510	COG2814	Major facilitator Superfamily
H4K32_RS05520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H4K32_RS05525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H4K32_RS05535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H4K32_RS05540	COG2409	Drug exporters of the RND superfamily
H4K32_RS05545	COG2197	response regulator
H4K32_RS05550	COG4585	Histidine kinase
H4K32_RS05560	COG5577	PFAM Coat F domain
H4K32_RS05565	COG1063	alcohol dehydrogenase
H4K32_RS05575	COG5577	PFAM Coat F domain
H4K32_RS05580	COG1309	transcriptional regulator
H4K32_RS05585	COG2814	Major facilitator Superfamily
H4K32_RS05600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4K32_RS05610	COG0789	Transcriptional regulator
H4K32_RS05615	COG1064	alcohol dehydrogenase
H4K32_RS05655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H4K32_RS05685	COG0277	FAD linked oxidase domain protein
H4K32_RS05705	COG0477	Major facilitator Superfamily
H4K32_RS05710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4K32_RS05720	COG2207	Transcriptional regulator
H4K32_RS05720	COG1917	Cupin 2, conserved barrel domain protein
H4K32_RS05725	COG1473	amidohydrolase
H4K32_RS05730	COG0814	amino acid
H4K32_RS05735	COG0251	oxidation-reduction process
H4K32_RS05740	COG1802	Transcriptional regulator
H4K32_RS05745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H4K32_RS05755	COG3621	Patatin-like phospholipase
H4K32_RS05770	COG1794	racemase activity, acting on amino acids and derivatives
H4K32_RS05775	COG1329	Transcriptional regulator
H4K32_RS05780	COG1278	Cold shock
H4K32_RS05785	COG2910	NAD(P)H-binding
H4K32_RS05790	COG1959	2 iron, 2 sulfur cluster binding
H4K32_RS05800	COG1846	Transcriptional regulator
H4K32_RS05805	COG1764	response to oxidative stress
H4K32_RS05815	COG0477	Major facilitator Superfamily
H4K32_RS05820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H4K32_RS05835	COG2249	NAD(P)H dehydrogenase (quinone) activity
H4K32_RS05840	COG0457	Tetratricopeptide repeat
H4K32_RS05890	COG2183	response to ionizing radiation
H4K32_RS05895	COG2208	phosphoserine phosphatase activity
H4K32_RS05900	COG1191	sigma factor activity
H4K32_RS05910	COG1366	Belongs to the anti-sigma-factor antagonist family
H4K32_RS05915	COG2208	phosphoserine phosphatase activity
H4K32_RS05920	COG2172	sigma factor antagonist activity
H4K32_RS05925	COG1366	Belongs to the anti-sigma-factor antagonist family
H4K32_RS05930	COG1366	Belongs to the anti-sigma-factor antagonist family
H4K32_RS05935	COG2337	Toxic component of a toxin-antitoxin (TA) module
H4K32_RS05940	COG0864	Transcriptional regulator
H4K32_RS05945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H4K32_RS05950	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H4K32_RS05960	COG0705	Rhomboid family
H4K32_RS05965	COG3428	Bacterial PH domain
H4K32_RS05970	COG3402	PFAM membrane-flanked domain
H4K32_RS05975	COG0513	Belongs to the DEAD box helicase family
H4K32_RS05980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H4K32_RS05990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H4K32_RS05995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H4K32_RS06010	COG1960	acyl-CoA dehydrogenase activity
H4K32_RS06020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H4K32_RS06025	COG1131	(ABC) transporter
H4K32_RS06030	COG0628	permease
H4K32_RS06035	COG1301	dicarboxylic acid transport
H4K32_RS06040	COG4565	transcriptional regulatory protein
H4K32_RS06045	COG3290	protein histidine kinase activity
H4K32_RS06050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H4K32_RS06055	COG3546	catalase activity
H4K32_RS06060	COG2329	Antibiotic biosynthesis monooxygenase
H4K32_RS06065	COG0662	Cupin 2, conserved barrel domain protein
H4K32_RS06070	COG3729	General stress protein
H4K32_RS06075	COG2217	Heavy metal translocating P-type atpase
H4K32_RS06080	COG2076	Multidrug Resistance protein
H4K32_RS06090	COG4876	unkown
H4K32_RS06100	COG1914	H( )-stimulated, divalent metal cation uptake system
H4K32_RS06120	COG0028	Belongs to the TPP enzyme family
H4K32_RS06125	COG0494	nUDIX hydrolase
H4K32_RS06130	COG0531	amino acid
H4K32_RS06140	COG1215	transferase activity, transferring glycosyl groups
H4K32_RS06145	COG5298	Protein conserved in bacteria
H4K32_RS06150	COG3706	GGDEF domain
H4K32_RS06155	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H4K32_RS06160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H4K32_RS06160	COG0551	DNA topoisomerase type I activity
H4K32_RS06165	COG1522	sequence-specific DNA binding
H4K32_RS06170	COG2814	Major facilitator Superfamily
H4K32_RS06180	COG3871	stress protein (general stress protein 26)
H4K32_RS06185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H4K32_RS06190	COG1917	Cupin 2, conserved barrel domain protein
H4K32_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS06200	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS06205	COG3711	transcriptional antiterminator
H4K32_RS06210	COG4989	oxidoreductase activity
H4K32_RS06215	COG0768	penicillin binding
H4K32_RS06220	COG2329	Antibiotic biosynthesis monooxygenase
H4K32_RS06230	COG2755	lipolytic protein G-D-S-L family
H4K32_RS06235	COG1414	Transcriptional regulator
H4K32_RS06240	COG1984	allophanate hydrolase subunit 2
H4K32_RS06245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H4K32_RS06255	COG1914	H( )-stimulated, divalent metal cation uptake system
H4K32_RS06265	COG0561	phosphatase activity
H4K32_RS06275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H4K32_RS06285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H4K32_RS06290	COG2213	PTS system mannitol-specific
H4K32_RS06300	COG1349	DNA-binding transcription factor activity
H4K32_RS06305	COG1276	copper resistance
H4K32_RS06305	COG2372	response to copper ion
H4K32_RS06310	COG4549	nuclear export factor GLE1
H4K32_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS06320	COG4975	Glucose uptake
H4K32_RS06325	COG1012	belongs to the aldehyde dehydrogenase family
H4K32_RS06330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H4K32_RS06335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4K32_RS06340	COG0640	Transcriptional regulator
H4K32_RS06345	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H4K32_RS06350	COG0778	Nitroreductase
H4K32_RS06355	COG1309	transcriptional regulator
H4K32_RS06360	COG2814	Major facilitator Superfamily
H4K32_RS06365	COG4607	ABC-type enterochelin transport system periplasmic component
H4K32_RS06370	COG4604	ABC transporter, ATP-binding protein
H4K32_RS06375	COG4605	iron ion homeostasis
H4K32_RS06380	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4K32_RS06385	COG0527	aspartate kinase activity
H4K32_RS06400	COG0457	Tetratricopeptide repeat
H4K32_RS06405	COG3850	Histidine kinase
H4K32_RS06405	COG5002	protein histidine kinase activity
H4K32_RS06410	COG0745	RESPONSE REGULATOR receiver
H4K32_RS06415	COG0577	efflux transmembrane transporter activity
H4K32_RS06420	COG1136	(ABC) transporter
H4K32_RS06425	COG2079	MmgE PrpD family protein
H4K32_RS06430	COG1473	amidohydrolase
H4K32_RS06435	COG1126	abc transporter atp-binding protein
H4K32_RS06440	COG0765	amino acid transport
H4K32_RS06445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H4K32_RS06450	COG0456	acetyltransferase
H4K32_RS06455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H4K32_RS06460	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H4K32_RS06470	COG0697	spore germination
H4K32_RS06480	COG5434	Belongs to the glycosyl hydrolase 28 family
H4K32_RS06485	COG3104	oligopeptide transport
H4K32_RS06500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H4K32_RS06505	COG0163	prenyltransferase activity
H4K32_RS06510	COG0583	DNA-binding transcription factor activity
H4K32_RS06515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H4K32_RS06520	COG0765	amino acid transport
H4K32_RS06525	COG1126	abc transporter atp-binding protein
H4K32_RS06530	COG2364	Membrane
H4K32_RS06545	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H4K32_RS06550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS06555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS06560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS06565	COG1733	regulation of RNA biosynthetic process
H4K32_RS06570	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H4K32_RS06575	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H4K32_RS06580	COG3209	COG3209 Rhs family protein
H4K32_RS06595	COG2723	6-phospho-beta-galactosidase activity
H4K32_RS06605	COG1714	RDD family
H4K32_RS06610	COG1063	alcohol dehydrogenase
H4K32_RS06615	COG0523	cobalamin synthesis protein
H4K32_RS06620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H4K32_RS06625	COG2146	nitrite reductase [NAD(P)H] activity
H4K32_RS06630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H4K32_RS06630	COG1587	Uroporphyrinogen-III synthase
H4K32_RS06640	COG2508	Transcriptional regulator
H4K32_RS06645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H4K32_RS06650	COG1012	belongs to the aldehyde dehydrogenase family
H4K32_RS06655	COG0506	proline dehydrogenase activity
H4K32_RS06660	COG3541	Predicted nucleotidyltransferase
H4K32_RS06665	COG3458	cephalosporin-C deacetylase activity
H4K32_RS06670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H4K32_RS06675	COG2271	Major facilitator Superfamily
H4K32_RS06685	COG1660	Displays ATPase and GTPase activities
H4K32_RS06700	COG3665	Urea carboxylase-associated protein
H4K32_RS06705	COG1113	amino acid transport
H4K32_RS06710	COG3403	YqcI/YcgG family
H4K32_RS06715	COG1280	lysine exporter protein (LysE YggA)
H4K32_RS06720	COG1846	Transcriptional regulator
H4K32_RS06725	COG2814	Major facilitator Superfamily
H4K32_RS06735	COG0366	Alpha amylase catalytic
H4K32_RS06745	COG1288	antiporter activity
H4K32_RS06750	COG1473	amidohydrolase
H4K32_RS06755	COG2113	Glycine betaine
H4K32_RS06760	COG4176	ABC-type proline glycine betaine transport system permease component
H4K32_RS06765	COG0517	IMP dehydrogenase activity
H4K32_RS06765	COG4175	Glycine betaine
H4K32_RS06770	COG0477	Major facilitator Superfamily
H4K32_RS06775	COG3853	Toxic anion resistance protein (TelA)
H4K32_RS06785	COG0861	Integral membrane protein TerC family
H4K32_RS06790	COG2310	stress, protein
H4K32_RS06795	COG2310	stress, protein
H4K32_RS06800	COG2310	stress, protein
H4K32_RS06805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H4K32_RS06810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H4K32_RS06815	COG1121	(ABC) transporter
H4K32_RS06820	COG0803	Belongs to the bacterial solute-binding protein 9 family
H4K32_RS06825	COG0366	Alpha amylase catalytic
H4K32_RS06830	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS06835	COG0457	Tetratricopeptide repeat
H4K32_RS06840	COG1876	peptidase activity
H4K32_RS06845	COG1595	DNA-templated transcription, initiation
H4K32_RS06850	COG1595	DNA-templated transcription, initiation
H4K32_RS06860	COG0667	Aldo Keto reductase
H4K32_RS06865	COG3012	SEC-C Motif Domain Protein
H4K32_RS06865	COG1405	negative regulation of cell septum assembly
H4K32_RS06870	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H4K32_RS06875	COG0252	asparaginase activity
H4K32_RS06880	COG1309	transcriptional regulator
H4K32_RS06885	COG0477	Major facilitator Superfamily
H4K32_RS06890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H4K32_RS06900	COG0805	protein transport
H4K32_RS06905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H4K32_RS06910	COG3540	Alkaline phosphatase
H4K32_RS06915	COG3773	Cell wall hydrolase
H4K32_RS06930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H4K32_RS06935	COG2259	Doxx family
H4K32_RS06940	COG0346	lactoylglutathione lyase activity
H4K32_RS06945	COG0778	Nitroreductase
H4K32_RS06950	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H4K32_RS06960	COG3173	Aminoglycoside phosphotransferase
H4K32_RS06965	COG0784	Response regulator, receiver
H4K32_RS06970	COG4191	Histidine kinase
H4K32_RS06975	COG2066	Belongs to the glutaminase family
H4K32_RS06980	COG1115	amino acid carrier protein
H4K32_RS06985	COG2040	homocysteine
H4K32_RS06990	COG0833	amino acid
H4K32_RS06995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H4K32_RS07000	COG1301	dicarboxylic acid transport
H4K32_RS07015	COG0688	phosphatidylethanolamine metabolic process
H4K32_RS07020	COG0586	Pfam SNARE associated Golgi protein
H4K32_RS07025	COG1183	phosphatidylcholine synthase activity
H4K32_RS07035	COG0371	Dehydrogenase
H4K32_RS07050	COG3409	Peptidoglycan-binding domain 1 protein
H4K32_RS07060	COG2368	4-hydroxyphenylacetate
H4K32_RS07070	COG2271	Major facilitator Superfamily
H4K32_RS07075	COG0584	glycerophosphoryl diester phosphodiesterase
H4K32_RS07080	COG0531	amino acid
H4K32_RS07120	COG1131	(ABC) transporter
H4K32_RS07125	COG2197	response regulator
H4K32_RS07130	COG4585	Histidine kinase
H4K32_RS07135	COG1011	Hydrolase
H4K32_RS07140	COG1113	amino acid transport
H4K32_RS07145	COG1846	Transcriptional regulator
H4K32_RS07150	COG1380	Effector of murein hydrolase LrgA
H4K32_RS07155	COG1346	cytolysis
H4K32_RS07195	COG4856	YbbR-like protein
H4K32_RS07200	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H4K32_RS07205	COG5662	AntiSigma factor
H4K32_RS07210	COG1595	DNA-templated transcription, initiation
H4K32_RS07240	COG1683	Conserved Protein
H4K32_RS07245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H4K32_RS07255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H4K32_RS07255	COG1263	PTS System
H4K32_RS07260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H4K32_RS07265	COG1472	Belongs to the glycosyl hydrolase 3 family
H4K32_RS07270	COG3876	Protein conserved in bacteria
H4K32_RS07275	COG2207	Transcriptional regulator
H4K32_RS07275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H4K32_RS07280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H4K32_RS07285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4K32_RS07290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4K32_RS07295	COG2819	hydrolase of the alpha beta superfamily
H4K32_RS07300	COG0385	Bile acid
H4K32_RS07305	COG0659	secondary active sulfate transmembrane transporter activity
H4K32_RS07320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H4K32_RS07325	COG0738	Major facilitator superfamily
H4K32_RS07385	COG0726	polysaccharide deacetylase
H4K32_RS07390	COG2194	sulfuric ester hydrolase activity
H4K32_RS07400	COG0489	protein tyrosine kinase activity
H4K32_RS07405	COG0860	N-Acetylmuramoyl-L-alanine amidase
H4K32_RS07415	COG2318	DinB family
H4K32_RS07420	COG2226	methyltransferase
H4K32_RS07440	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H4K32_RS07445	COG1122	ATPase activity
H4K32_RS07450	COG1122	ATPase activity
H4K32_RS07475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H4K32_RS07485	COG0024	Methionine aminopeptidase
H4K32_RS07495	COG0201	protein transport
H4K32_RS07605	COG0596	Alpha beta hydrolase
H4K32_RS07630	COG1358	cellular component organization or biogenesis
H4K32_RS07645	COG2813	Specifically methylates the guanine in position
H4K32_RS07670	COG0250	Participates in transcription elongation, termination and antitermination
H4K32_RS07675	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H4K32_RS07685	COG1595	DNA-templated transcription, initiation
H4K32_RS07690	COG3688	RNA-binding protein containing a PIN domain
H4K32_RS07695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H4K32_RS07700	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H4K32_RS07710	COG1045	serine acetyltransferase
H4K32_RS07730	COG4956	integral membrane protein (PIN domain superfamily)
H4K32_RS07735	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H4K32_RS07740	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H4K32_RS07745	COG0542	response to heat
H4K32_RS07755	COG3880	PFAM UvrB UvrC protein
H4K32_RS07760	COG4463	regulation of RNA biosynthetic process
H4K32_RS07840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H4K32_RS07845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H4K32_RS07850	COG1396	sequence-specific DNA binding
H4K32_RS07855	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H4K32_RS07860	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H4K32_RS07865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H4K32_RS07870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H4K32_RS07875	COG0512	Glutamine amidotransferase of anthranilate synthase
H4K32_RS07880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H4K32_RS07885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H4K32_RS07890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H4K32_RS07905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H4K32_RS07915	COG0037	tRNA processing
H4K32_RS07920	COG0515	serine threonine protein kinase
H4K32_RS07925	COG2304	oxidoreductase activity
H4K32_RS07930	COG2208	phosphoserine phosphatase activity
H4K32_RS07945	COG1098	S1 RNA binding domain
H4K32_RS07950	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H4K32_RS07965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H4K32_RS07970	COG3956	TIGRFAM MazG family protein
H4K32_RS07975	COG2244	polysaccharide biosynthetic process
H4K32_RS07980	COG2002	toxin-antitoxin pair type II binding
H4K32_RS07985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H4K32_RS08005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H4K32_RS08020	COG0251	oxidation-reduction process
H4K32_RS08025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H4K32_RS08040	COG4466	Protein conserved in bacteria
H4K32_RS08050	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H4K32_RS08055	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H4K32_RS08060	COG3584	3D domain protein
H4K32_RS08060	COG3583	domain protein
H4K32_RS08065	COG0084	hydrolase, TatD family'
H4K32_RS08070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H4K32_RS08070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H4K32_RS08075	COG2002	toxin-antitoxin pair type II binding
H4K32_RS08080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H4K32_RS08090	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H4K32_RS08100	COG1774	PSP1 C-terminal conserved region
H4K32_RS08105	COG0470	DNA polymerase III
H4K32_RS08110	COG1728	Protein conserved in bacteria
H4K32_RS08115	COG3870	Protein conserved in bacteria
H4K32_RS08125	COG1982	Orn Lys Arg decarboxylase major
H4K32_RS08130	COG3853	Toxic anion resistance protein (TelA)
H4K32_RS08135	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
H4K32_RS08185	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H4K32_RS08190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H4K32_RS08200	COG0590	tRNA wobble adenosine to inosine editing
H4K32_RS08205	COG1335	isochorismatase
H4K32_RS08210	COG1388	LysM domain
H4K32_RS08210	COG3858	chitin binding
H4K32_RS08215	COG1428	Deoxynucleoside kinase
H4K32_RS08220	COG1428	Deoxynucleoside kinase
H4K32_RS08230	COG1929	Belongs to the glycerate kinase type-1 family
H4K32_RS08250	COG1686	Belongs to the peptidase S11 family
H4K32_RS08255	COG0517	IMP dehydrogenase activity
H4K32_RS08255	COG0516	GMP reductase activity
H4K32_RS08290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H4K32_RS08295	COG0187	DNA topoisomerase II activity
H4K32_RS08310	COG2501	S4 domain
H4K32_RS08315	COG0592	DNA-directed DNA polymerase activity
H4K32_RS08335	COG0706	membrane insertase activity
H4K32_RS08340	COG1847	R3H domain protein
H4K32_RS08365	COG1192	Involved in chromosome partitioning
H4K32_RS08370	COG1475	DNA binding
H4K32_RS08385	COG3949	Membrane
H4K32_RS08390	COG4481	Protein conserved in bacteria
H4K32_RS08395	COG0243	molybdopterin cofactor binding
H4K32_RS08400	COG0012	GTP binding
H4K32_RS08410	COG0629	single-stranded DNA binding
H4K32_RS08420	COG2169	Transcriptional regulator
H4K32_RS08425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H4K32_RS08430	COG0708	Exodeoxyribonuclease III
H4K32_RS08435	COG1609	Transcriptional regulator
H4K32_RS08440	COG0346	lactoylglutathione lyase activity
H4K32_RS08445	COG0477	Major facilitator Superfamily
H4K32_RS08445	COG2814	Major facilitator Superfamily
H4K32_RS08450	COG1266	CAAX protease self-immunity
H4K32_RS08455	COG1331	Highly conserved protein containing a thioredoxin domain
H4K32_RS08460	COG0697	spore germination
H4K32_RS08465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4K32_RS08475	COG1846	Transcriptional regulator
H4K32_RS08480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H4K32_RS08485	COG1846	Transcriptional regulator
H4K32_RS08490	COG0778	Nitroreductase
H4K32_RS08500	COG2211	Major facilitator Superfamily
H4K32_RS08505	COG2318	DinB family
H4K32_RS08510	COG1802	Transcriptional regulator
H4K32_RS08515	COG1621	beta-fructofuranosidase activity
H4K32_RS08520	COG1621	beta-fructofuranosidase activity
H4K32_RS08525	COG0697	spore germination
H4K32_RS08535	COG1733	regulation of RNA biosynthetic process
H4K32_RS08540	COG5577	PFAM Coat F domain
H4K32_RS08550	COG4241	membrane
H4K32_RS08555	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H4K32_RS08575	COG0438	transferase activity, transferring glycosyl groups
H4K32_RS08580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H4K32_RS08590	COG0297	glycogen (starch) synthase activity
H4K32_RS08595	COG3093	addiction module antidote protein HigA
H4K32_RS08610	COG0305	Participates in initiation and elongation during chromosome replication
H4K32_RS08615	COG0346	lactoylglutathione lyase activity
H4K32_RS08645	COG0745	RESPONSE REGULATOR receiver
H4K32_RS08650	COG5002	protein histidine kinase activity
H4K32_RS08655	COG4863	YycH protein
H4K32_RS08660	COG4853	Protein conserved in bacteria
H4K32_RS08665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H4K32_RS08670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H4K32_RS08675	COG0745	RESPONSE REGULATOR receiver
H4K32_RS08680	COG5002	protein histidine kinase activity
H4K32_RS08685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H4K32_RS08700	COG0488	(ABC) transporter
H4K32_RS08710	COG3829	transcription factor binding
H4K32_RS08715	COG0640	Transcriptional regulator
H4K32_RS08720	COG5658	integral membrane protein
H4K32_RS08725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H4K32_RS08730	COG0833	amino acid
H4K32_RS08735	COG0010	Belongs to the arginase family
H4K32_RS08740	COG0457	Tetratricopeptide repeat
H4K32_RS08745	COG0456	acetyltransferase
H4K32_RS08750	COG0667	Aldo Keto reductase
H4K32_RS08755	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
H4K32_RS08825	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H4K32_RS08830	COG2068	MobA-Related Protein
H4K32_RS08845	COG2080	2 iron, 2 sulfur cluster binding
H4K32_RS08865	COG3634	alkyl hydroperoxide reductase activity
H4K32_RS08870	COG0450	alkyl hydroperoxide reductase
H4K32_RS08880	COG1714	RDD family
H4K32_RS08885	COG2814	Major facilitator Superfamily
H4K32_RS08890	COG0640	Transcriptional regulator
H4K32_RS08900	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H4K32_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
H4K32_RS08910	COG1309	transcriptional regulator
H4K32_RS08915	COG3239	Fatty acid desaturase
H4K32_RS08920	COG4585	Histidine kinase
H4K32_RS08925	COG2197	response regulator
H4K32_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS08940	COG2814	Major facilitator Superfamily
H4K32_RS08945	COG0667	Aldo Keto reductase
H4K32_RS08950	COG1349	DNA-binding transcription factor activity
H4K32_RS08980	COG2814	Major facilitator Superfamily
H4K32_RS08990	COG1082	Xylose isomerase domain protein TIM barrel
H4K32_RS09005	COG0745	RESPONSE REGULATOR receiver
H4K32_RS09010	COG2205	protein histidine kinase activity
H4K32_RS09015	COG1136	(ABC) transporter
H4K32_RS09020	COG0577	efflux transmembrane transporter activity
H4K32_RS09025	COG5294	Protein conserved in bacteria
H4K32_RS09030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H4K32_RS09060	COG0561	phosphatase activity
H4K32_RS09065	COG2390	Transcriptional regulator
H4K32_RS09075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H4K32_RS09080	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H4K32_RS09085	COG0833	amino acid
H4K32_RS09090	COG0010	Belongs to the arginase family
H4K32_RS09115	COG3507	Belongs to the glycosyl hydrolase 43 family
H4K32_RS09155	COG2723	6-phospho-beta-galactosidase activity
H4K32_RS09160	COG0589	response to stress
H4K32_RS09165	COG0697	spore germination
H4K32_RS09210	COG0513	Belongs to the DEAD box helicase family
H4K32_RS09215	COG2270	Major facilitator Superfamily
H4K32_RS09225	COG2273	Hydrolase Family 16
H4K32_RS09230	COG2851	Citrate transporter
H4K32_RS09235	COG0693	protein deglycase activity
H4K32_RS09235	COG0753	catalase activity
H4K32_RS09250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H4K32_RS09255	COG0500	methyltransferase
H4K32_RS09260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H4K32_RS09265	COG4894	glucomannan catabolic process
H4K32_RS09280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H4K32_RS09290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H4K32_RS09295	COG2508	Transcriptional regulator
H4K32_RS09300	COG3842	ATPase activity
H4K32_RS09305	COG0726	polysaccharide deacetylase
H4K32_RS09310	COG3493	citrate carrier protein
H4K32_RS09315	COG1271	oxidase subunit
H4K32_RS09320	COG1294	oxidase, subunit
H4K32_RS09325	COG4988	ABC transporter
H4K32_RS09330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H4K32_RS09335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H4K32_RS09340	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H4K32_RS09345	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
H4K32_RS09350	COG0753	catalase activity
H4K32_RS09360	COG1482	cell wall glycoprotein biosynthetic process
H4K32_RS09365	COG1940	carbohydrate kinase activity
H4K32_RS09370	COG2723	6-phospho-beta-galactosidase activity
H4K32_RS09375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H4K32_RS09380	COG1447	Phosphotransferase system cellobiose-specific component IIA
H4K32_RS09385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H4K32_RS09390	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H4K32_RS09395	COG0640	Transcriptional regulator
H4K32_RS09405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4K32_RS09410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4K32_RS09420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H4K32_RS09420	COG3711	transcriptional antiterminator
H4K32_RS09425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H4K32_RS09430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H4K32_RS09435	COG1447	Phosphotransferase system cellobiose-specific component IIA
H4K32_RS09440	COG1486	melibiose metabolic process
H4K32_RS09445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H4K32_RS09450	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H4K32_RS09460	COG1696	Membrane protein involved in D-alanine export
H4K32_RS09475	COG1575	Belongs to the MenA family. Type 1 subfamily
H4K32_RS09480	COG2357	RelA SpoT domain protein
H4K32_RS09485	COG1442	glycosyl transferase family 8
H4K32_RS09490	COG1404	Belongs to the peptidase S8 family
H4K32_RS09495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H4K32_RS09500	COG0346	lactoylglutathione lyase activity
H4K32_RS09505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H4K32_RS09510	COG0789	Transcriptional regulator
H4K32_RS09515	COG4895	conserved protein (DUF2196)
H4K32_RS09520	COG1346	cytolysis
H4K32_RS09530	COG0583	DNA-binding transcription factor activity
H4K32_RS09545	COG2822	iron ion transport
H4K32_RS09550	COG2837	iron assimilation
H4K32_RS09555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H4K32_RS09575	COG1309	transcriptional regulator
H4K32_RS09580	COG2246	polysaccharide biosynthetic process
H4K32_RS09590	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H4K32_RS09595	COG2261	transglycosylase associated protein
H4K32_RS09600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H4K32_RS09605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H4K32_RS09625	COG0454	-acetyltransferase
H4K32_RS09630	COG0772	Belongs to the SEDS family
H4K32_RS09635	COG0778	Nitroreductase
H4K32_RS09640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H4K32_RS09645	COG1404	Belongs to the peptidase S8 family
H4K32_RS09655	COG3711	transcriptional antiterminator
H4K32_RS09660	COG1263	PTS System
H4K32_RS09660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H4K32_RS09665	COG1621	beta-fructofuranosidase activity
H4K32_RS09675	COG0351	phosphomethylpyrimidine kinase
H4K32_RS09680	COG1695	Transcriptional regulator
H4K32_RS09695	COG1216	Glycosyl transferase, family 2
H4K32_RS09710	COG2233	PERMEase
H4K32_RS09715	COG2363	Small membrane protein
H4K32_RS09725	COG0463	Glycosyl transferase, family 2
H4K32_RS09730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H4K32_RS09735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H4K32_RS09740	COG0456	acetyltransferase
H4K32_RS09745	COG2089	acid synthase
H4K32_RS09750	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H4K32_RS09755	COG3980	spore coat polysaccharide biosynthesis protein
H4K32_RS09760	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H4K32_RS09765	COG1088	dTDP-glucose 4,6-dehydratase activity
H4K32_RS09770	COG1091	dTDP-4-dehydrorhamnose reductase activity
H4K32_RS09775	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
H4K32_RS09785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H4K32_RS09790	COG1012	belongs to the aldehyde dehydrogenase family
H4K32_RS09795	COG4187	Peptidase family M20/M25/M40
H4K32_RS09800	COG0833	amino acid
H4K32_RS09805	COG2814	Major facilitator Superfamily
H4K32_RS09810	COG2814	Major facilitator Superfamily
H4K32_RS09840	COG0436	Aminotransferase
H4K32_RS09845	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS09855	COG0280	phosphate acetyltransferase
H4K32_RS09860	COG2855	membrane
H4K32_RS09865	COG0583	DNA-binding transcription factor activity
H4K32_RS09885	COG1695	Transcriptional regulator
H4K32_RS09900	COG1078	dGTPase activity
H4K32_RS09905	COG3465	dGTPase activity
H4K32_RS09910	COG0531	amino acid
H4K32_RS09915	COG1846	Transcriptional regulator
H4K32_RS09920	COG1942	4-Oxalocrotonate Tautomerase
H4K32_RS09925	COG1994	Peptidase M50
H4K32_RS09940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H4K32_RS09945	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H4K32_RS09950	COG0010	Belongs to the arginase family
H4K32_RS09985	COG0457	Tetratricopeptide repeat
H4K32_RS09990	COG4506	Protein conserved in bacteria
H4K32_RS10000	COG2223	nitrite transmembrane transporter activity
H4K32_RS10005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H4K32_RS10015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H4K32_RS10020	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H4K32_RS10025	COG1140	nitrate reductase beta subunit
H4K32_RS10030	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H4K32_RS10035	COG2181	nitrate reductase activity
H4K32_RS10045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H4K32_RS10050	COG1132	(ABC) transporter
H4K32_RS10065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H4K32_RS10070	COG2181	nitrate reductase activity
H4K32_RS10070	COG0247	lactate metabolic process
H4K32_RS10085	COG4821	SIS domain
H4K32_RS10090	COG2204	response regulator
H4K32_RS10095	COG0191	fructose-bisphosphate aldolase activity
H4K32_RS10105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H4K32_RS10110	COG1494	fructose-1,6-bisphosphatase
H4K32_RS10115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H4K32_RS10130	COG0281	malic enzyme
H4K32_RS10135	COG0679	Auxin Efflux Carrier
H4K32_RS10140	COG0789	Transcriptional regulator
H4K32_RS10145	COG0346	lactoylglutathione lyase activity
H4K32_RS10150	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H4K32_RS10155	COG2890	protein-(glutamine-N5) methyltransferase activity
H4K32_RS10175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H4K32_RS10180	COG0009	L-threonylcarbamoyladenylate synthase
H4K32_RS10190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H4K32_RS10195	COG0698	ribose 5-phosphate isomerase
H4K32_RS10265	COG4836	Membrane
H4K32_RS10275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H4K32_RS10280	COG2385	sporulation resulting in formation of a cellular spore
H4K32_RS10285	COG2304	oxidoreductase activity
H4K32_RS10290	COG2304	oxidoreductase activity
H4K32_RS10300	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H4K32_RS10310	COG0457	Tetratricopeptide repeat
H4K32_RS10315	COG1994	Peptidase M50
H4K32_RS10320	COG3237	CsbD-like
H4K32_RS10325	COG0831	urea catabolic process
H4K32_RS10340	COG1959	2 iron, 2 sulfur cluster binding
H4K32_RS10350	COG0726	polysaccharide deacetylase
H4K32_RS10360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H4K32_RS10375	COG1247	-acetyltransferase
H4K32_RS10380	COG0739	heme binding
H4K32_RS10390	COG0671	phosphoesterase, PA-phosphatase related
H4K32_RS10395	COG0772	Belongs to the SEDS family
H4K32_RS10400	COG0347	Belongs to the P(II) protein family
H4K32_RS10405	COG0004	ammonium transporteR
H4K32_RS10410	COG1335	isochorismatase
H4K32_RS10415	COG0477	Major facilitator Superfamily
H4K32_RS10420	COG1953	Uracil, thiamine, allantoin
H4K32_RS10425	COG2814	Major facilitator Superfamily
H4K32_RS10430	COG1846	Transcriptional regulator
H4K32_RS10435	COG1609	Transcriptional regulator
H4K32_RS10440	COG1077	Cell shape determining protein MreB Mrl
H4K32_RS10445	COG4786	Flagellar basal body rod
H4K32_RS10450	COG4786	Flagellar basal body rod
H4K32_RS10455	COG0457	Tetratricopeptide repeat
H4K32_RS10480	COG0629	single-stranded DNA binding
H4K32_RS10485	COG1349	DNA-binding transcription factor activity
H4K32_RS10490	COG0561	phosphatase activity
H4K32_RS10495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H4K32_RS10500	COG4715	Zinc finger, swim domain protein
H4K32_RS10510	COG3944	biosynthesis protein
H4K32_RS10515	COG0489	protein tyrosine kinase activity
H4K32_RS10520	COG4464	protein tyrosine phosphatase activity
H4K32_RS10525	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H4K32_RS10530	COG3878	Protein conserved in bacteria
H4K32_RS10570	COG0583	DNA-binding transcription factor activity
H4K32_RS10575	COG0655	NAD(P)H dehydrogenase (quinone) activity
H4K32_RS10585	COG2059	Chromate
H4K32_RS10590	COG2059	Chromate
H4K32_RS10595	COG1522	sequence-specific DNA binding
H4K32_RS10600	COG0405	Gamma-glutamyltransferase
H4K32_RS10610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H4K32_RS10620	COG5337	Spore coat protein CotH
H4K32_RS10635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H4K32_RS10640	COG0583	DNA-binding transcription factor activity
H4K32_RS10645	COG0028	Belongs to the TPP enzyme family
H4K32_RS10650	COG3527	Alpha-acetolactate decarboxylase
H4K32_RS10655	COG2249	NAD(P)H dehydrogenase (quinone) activity
H4K32_RS10660	COG3103	Sh3 type 3 domain protein
H4K32_RS10665	COG1879	ABC-type sugar transport system periplasmic component
H4K32_RS10670	COG1172	Belongs to the binding-protein-dependent transport system permease family
H4K32_RS10675	COG1129	ABC transporter
H4K32_RS10685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H4K32_RS10690	COG1609	Transcriptional regulator
H4K32_RS10700	COG0814	amino acid
H4K32_RS10705	COG0697	spore germination
H4K32_RS10710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H4K32_RS10720	COG2843	Capsule synthesis protein
H4K32_RS10730	COG0791	NLP P60 protein
H4K32_RS10735	COG2433	Pfam Transposase IS66
H4K32_RS10740	COG0561	phosphatase activity
H4K32_RS10745	COG1316	TRANSCRIPTIONal
H4K32_RS10750	COG2814	Major facilitator Superfamily
H4K32_RS10755	COG1215	transferase activity, transferring glycosyl groups
H4K32_RS10765	COG0814	amino acid
H4K32_RS10770	COG0697	spore germination
H4K32_RS10775	COG1482	cell wall glycoprotein biosynthetic process
H4K32_RS10780	COG4193	domain, Protein
H4K32_RS10785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H4K32_RS10790	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H4K32_RS10795	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H4K32_RS10805	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H4K32_RS10810	COG1682	transport, permease protein
H4K32_RS10815	COG1134	teichoic acid transport
H4K32_RS10820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H4K32_RS10825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H4K32_RS10830	COG1316	TRANSCRIPTIONal
H4K32_RS10840	COG2385	sporulation resulting in formation of a cellular spore
H4K32_RS10840	COG2247	cell wall binding repeat
H4K32_RS10845	COG0860	N-Acetylmuramoyl-L-alanine amidase
H4K32_RS10845	COG2247	cell wall binding repeat
H4K32_RS10855	COG2244	polysaccharide biosynthetic process
H4K32_RS10860	COG0297	glycogen (starch) synthase activity
H4K32_RS10860	COG0438	transferase activity, transferring glycosyl groups
H4K32_RS10865	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H4K32_RS10870	COG3307	-O-antigen
H4K32_RS10875	COG3206	protein involved in exopolysaccharide biosynthesis
H4K32_RS10880	COG1215	transferase activity, transferring glycosyl groups
H4K32_RS10885	COG0438	transferase activity, transferring glycosyl groups
H4K32_RS10890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H4K32_RS10895	COG1316	TRANSCRIPTIONal
H4K32_RS10900	COG1739	Uncharacterized protein family UPF0029
H4K32_RS10905	COG4585	Histidine kinase
H4K32_RS10910	COG2197	response regulator
H4K32_RS10915	COG1307	EDD domain protein, DegV family
H4K32_RS10920	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H4K32_RS10930	COG1040	competence protein
H4K32_RS10940	COG2747	anti-sigma28 factor FlgM
H4K32_RS10945	COG3418	PFAM FlgN family protein
H4K32_RS10950	COG4786	Flagellar basal body rod
H4K32_RS10950	COG1256	bacterial-type flagellum assembly
H4K32_RS10955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H4K32_RS10975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H4K32_RS10980	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H4K32_RS10985	COG1516	flagellar protein fliS
H4K32_RS11000	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H4K32_RS11015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H4K32_RS11020	COG2010	Cytochrome c
H4K32_RS11025	COG2884	Cell division ATP-binding protein ftsE
H4K32_RS11030	COG2177	Part of the ABC transporter FtsEX involved in
H4K32_RS11035	COG3420	alginic acid biosynthetic process
H4K32_RS11040	COG3409	Peptidoglycan-binding domain 1 protein
H4K32_RS11040	COG0793	Belongs to the peptidase S41A family
H4K32_RS11050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H4K32_RS11065	COG2814	Major facilitator Superfamily
H4K32_RS11070	COG1309	transcriptional regulator
H4K32_RS11075	COG3848	Pyruvate phosphate dikinase
H4K32_RS11075	COG0574	Belongs to the PEP-utilizing enzyme family
H4K32_RS11080	COG4897	Protein conserved in bacteria
H4K32_RS11090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H4K32_RS11105	COG3595	metallopeptidase activity
H4K32_RS11110	COG1983	PspC domain protein
H4K32_RS11115	COG1950	PFAM Membrane protein of
H4K32_RS11120	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H4K32_RS11125	COG1309	transcriptional regulator
H4K32_RS11130	COG2188	Transcriptional regulator
H4K32_RS11140	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H4K32_RS11160	COG0110	maltose O-acetyltransferase activity
H4K32_RS11165	COG4990	cell redox homeostasis
H4K32_RS11180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H4K32_RS11205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H4K32_RS11205	COG0140	phosphoribosyl-ATP diphosphatase activity
H4K32_RS11210	COG1132	(ABC) transporter
H4K32_RS11220	COG0745	RESPONSE REGULATOR receiver
H4K32_RS11225	COG5002	protein histidine kinase activity
H4K32_RS11230	COG0457	Tetratricopeptide repeat
H4K32_RS11235	COG3883	PFAM NLP P60 protein
H4K32_RS11235	COG0791	NLP P60 protein
H4K32_RS11240	COG0492	ferredoxin-NADP+ reductase activity
H4K32_RS11245	COG1051	belongs to the nudix hydrolase family
H4K32_RS11255	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H4K32_RS11265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H4K32_RS11270	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H4K32_RS11275	COG4290	ribonuclease
H4K32_RS11280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H4K32_RS11285	COG0288	reversible hydration of carbon dioxide
H4K32_RS11290	COG0659	secondary active sulfate transmembrane transporter activity
H4K32_RS11295	COG1694	Mazg nucleotide pyrophosphohydrolase
H4K32_RS11300	COG1611	Belongs to the LOG family
H4K32_RS11305	COG0477	Major facilitator Superfamily
H4K32_RS11305	COG2814	Major facilitator Superfamily
H4K32_RS11310	COG2828	Protein conserved in bacteria
H4K32_RS11315	COG0583	DNA-binding transcription factor activity
H4K32_RS11325	COG1609	Transcriptional regulator
H4K32_RS11330	COG2223	nitrite transmembrane transporter activity
H4K32_RS11390	COG3479	Phenolic acid decarboxylase
H4K32_RS11395	COG0456	acetyltransferase
H4K32_RS11400	COG2364	Membrane
H4K32_RS11405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H4K32_RS11415	COG2272	Belongs to the type-B carboxylesterase lipase family
H4K32_RS11420	COG1396	sequence-specific DNA binding
H4K32_RS11425	COG3944	biosynthesis protein
H4K32_RS11430	COG0489	protein tyrosine kinase activity
H4K32_RS11435	COG1086	Polysaccharide biosynthesis protein
H4K32_RS11440	COG0438	transferase activity, transferring glycosyl groups
H4K32_RS11445	COG1215	transferase activity, transferring glycosyl groups
H4K32_RS11450	COG0438	transferase activity, transferring glycosyl groups
H4K32_RS11460	COG1216	Glycosyl transferase, family 2
H4K32_RS11465	COG5039	Polysaccharide pyruvyl transferase
H4K32_RS11470	COG1216	Glycosyl transferase, family 2
H4K32_RS11475	COG2244	polysaccharide biosynthetic process
H4K32_RS11480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H4K32_RS11485	COG0110	maltose O-acetyltransferase activity
H4K32_RS11490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H4K32_RS11495	COG5039	Polysaccharide pyruvyl transferase
H4K32_RS11505	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H4K32_RS11510	COG1620	l-lactate permease
H4K32_RS11515	COG2186	Transcriptional regulator
H4K32_RS11520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4K32_RS11545	COG1070	Carbohydrate kinase
H4K32_RS11550	COG1737	Transcriptional regulator
H4K32_RS11555	COG1113	amino acid transport
H4K32_RS11560	COG0697	spore germination
H4K32_RS11565	COG0583	DNA-binding transcription factor activity
H4K32_RS11575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H4K32_RS11580	COG1609	Transcriptional regulator
H4K32_RS11585	COG2814	Major facilitator Superfamily
H4K32_RS11590	COG2390	Transcriptional regulator
H4K32_RS11595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H4K32_RS11600	COG0126	phosphoglycerate kinase activity
H4K32_RS11620	COG2234	aminopeptidase activity
H4K32_RS11630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H4K32_RS11635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS11640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H4K32_RS11655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H4K32_RS11670	COG0456	acetyltransferase
H4K32_RS11675	COG4640	response to antibiotic
H4K32_RS11680	COG3064	Membrane
H4K32_RS11685	COG2095	MarC family integral membrane protein
H4K32_RS11690	COG1510	regulation of RNA biosynthetic process
H4K32_RS11695	COG0517	IMP dehydrogenase activity
H4K32_RS11695	COG1125	glycine betaine transport
H4K32_RS11700	COG1174	glycine betaine transport
H4K32_RS11705	COG1732	Glycine betaine
H4K32_RS11710	COG1174	glycine betaine transport
H4K32_RS11715	COG1510	regulation of RNA biosynthetic process
H4K32_RS11720	COG0517	IMP dehydrogenase activity
H4K32_RS11720	COG1125	glycine betaine transport
H4K32_RS11725	COG1174	glycine betaine transport
H4K32_RS11730	COG1732	Glycine betaine
H4K32_RS11735	COG1174	glycine betaine transport
H4K32_RS11740	COG1131	(ABC) transporter
H4K32_RS11765	COG1733	regulation of RNA biosynthetic process
H4K32_RS11770	COG1396	sequence-specific DNA binding
H4K32_RS11775	COG1396	sequence-specific DNA binding
H4K32_RS11780	COG1476	TRANSCRIPTIONal
H4K32_RS11785	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H4K32_RS11790	COG1647	Serine aminopeptidase, S33
H4K32_RS11795	COG0557	exoribonuclease II activity
H4K32_RS11810	COG2732	(Barnase) inhibitor
H4K32_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS11820	COG0583	DNA-binding transcription factor activity
H4K32_RS11825	COG0454	-acetyltransferase
H4K32_RS11830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H4K32_RS11835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H4K32_RS11840	COG0765	amino acid transport
H4K32_RS11845	COG0765	amino acid transport
H4K32_RS11850	COG1126	abc transporter atp-binding protein
H4K32_RS11855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H4K32_RS11860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H4K32_RS11865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H4K32_RS11875	COG0673	inositol 2-dehydrogenase activity
H4K32_RS11880	COG1937	Protein conserved in bacteria
H4K32_RS11885	COG2608	mercury ion transmembrane transporter activity
H4K32_RS11890	COG2217	Heavy metal translocating P-type atpase
H4K32_RS11895	COG2217	Heavy metal translocating P-type atpase
H4K32_RS11900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H4K32_RS11905	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H4K32_RS11915	COG2860	membrane
H4K32_RS11920	COG3973	AAA domain
H4K32_RS11925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H4K32_RS11945	COG0656	L-ascorbic acid biosynthetic process
H4K32_RS11950	COG0842	Transport permease protein
H4K32_RS11960	COG1131	(ABC) transporter
H4K32_RS11965	COG3850	Histidine kinase
H4K32_RS11970	COG2197	response regulator
H4K32_RS11975	COG4149	molybdate abc transporter
H4K32_RS11980	COG0725	ABC transporter, periplasmic molybdate-binding protein
H4K32_RS11985	COG1910	domain protein
H4K32_RS11990	COG1368	sulfuric ester hydrolase activity
H4K32_RS11995	COG1988	membrane-bound metal-dependent
H4K32_RS12005	COG0531	amino acid
H4K32_RS12010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H4K32_RS12015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H4K32_RS12020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4K32_RS12025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4K32_RS12030	COG1120	ATPase activity
H4K32_RS12040	COG2140	Oxalate decarboxylase
H4K32_RS12050	COG1191	sigma factor activity
H4K32_RS12060	COG0745	RESPONSE REGULATOR receiver
H4K32_RS12065	COG2205	protein histidine kinase activity
H4K32_RS12070	COG3386	PFAM SMP-30 Gluconolaconase
H4K32_RS12075	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS12080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H4K32_RS12085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4K32_RS12090	COG1120	ATPase activity
H4K32_RS12095	COG2096	Adenosyltransferase
H4K32_RS12100	COG2814	Major facilitator Superfamily
H4K32_RS12105	COG4758	membrane
H4K32_RS12110	COG1842	Phage shock protein A
H4K32_RS12115	COG3595	metallopeptidase activity
H4K32_RS12120	COG4758	membrane
H4K32_RS12125	COG4585	Histidine kinase
H4K32_RS12130	COG2197	response regulator
H4K32_RS12140	COG0814	amino acid
H4K32_RS12145	COG0697	spore germination
H4K32_RS12155	COG0114	fumarate hydratase activity
H4K32_RS12160	COG1309	transcriptional regulator
H4K32_RS12170	COG2205	protein histidine kinase activity
H4K32_RS12170	COG2770	Histidine kinase
H4K32_RS12175	COG0745	RESPONSE REGULATOR receiver
H4K32_RS12180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H4K32_RS12185	COG0783	Belongs to the Dps family
H4K32_RS12190	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS12205	COG1120	ATPase activity
H4K32_RS12225	COG0583	DNA-binding transcription factor activity
H4K32_RS12230	COG0477	Major facilitator Superfamily
H4K32_RS12235	COG1846	Transcriptional regulator
H4K32_RS12240	COG5577	PFAM Coat F domain
H4K32_RS12260	COG1024	Enoyl-CoA hydratase
H4K32_RS12260	COG1250	3-hydroxyacyl-CoA dehydrogenase
H4K32_RS12265	COG0183	Belongs to the thiolase family
H4K32_RS12270	COG1960	acyl-CoA dehydrogenase activity
H4K32_RS12275	COG1393	Belongs to the ArsC family
H4K32_RS12290	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H4K32_RS12295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H4K32_RS12305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H4K32_RS12310	COG2011	ABC-type metal ion transport system permease component
H4K32_RS12315	COG1464	Belongs to the NlpA lipoprotein family
H4K32_RS12320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H4K32_RS12330	COG0396	ATPase activity
H4K32_RS12335	COG0719	Fe-S assembly protein
H4K32_RS12340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H4K32_RS12345	COG0822	iron-sulfur transferase activity
H4K32_RS12350	COG0719	Fe-S assembly protein
H4K32_RS12355	COG3409	Peptidoglycan-binding domain 1 protein
H4K32_RS12365	COG2226	methyltransferase
H4K32_RS12370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H4K32_RS12375	COG0322	excinuclease ABC activity
H4K32_RS12390	COG0789	Transcriptional regulator
H4K32_RS12395	COG2222	sugar isomerase
H4K32_RS12400	COG1653	transport
H4K32_RS12405	COG1175	transmembrane transport
H4K32_RS12410	COG0395	ABC-type sugar transport system, permease component
H4K32_RS12415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H4K32_RS12420	COG2188	Transcriptional regulator
H4K32_RS12425	COG3842	ATPase activity
H4K32_RS12430	COG2356	endonuclease I
H4K32_RS12435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H4K32_RS12440	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H4K32_RS12445	COG2814	Major facilitator Superfamily
H4K32_RS12455	COG2508	Transcriptional regulator
H4K32_RS12470	COG1801	Protein of unknown function DUF72
H4K32_RS12475	COG0730	response to heat
H4K32_RS12480	COG0737	Belongs to the 5'-nucleotidase family
H4K32_RS12490	COG0739	heme binding
H4K32_RS12500	COG4470	Protein conserved in bacteria
H4K32_RS12505	COG2445	Protein of unknown function DUF86
H4K32_RS12510	COG0647	UMP catabolic process
H4K32_RS12515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H4K32_RS12520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H4K32_RS12525	COG0460	homoserine dehydrogenase
H4K32_RS12530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H4K32_RS12540	COG4946	Tricorn protease homolog
H4K32_RS12540	COG1506	peptidase
H4K32_RS12540	COG0823	Involved in the tonB-independent uptake of proteins
H4K32_RS12545	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H4K32_RS12550	COG4837	Protein of unknown function (DUF1462)
H4K32_RS12555	COG1252	NADH dehydrogenase
H4K32_RS12565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H4K32_RS12575	COG0316	Belongs to the HesB IscA family
H4K32_RS12580	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H4K32_RS12605	COG1131	(ABC) transporter
H4K32_RS12635	COG1252	NADH dehydrogenase
H4K32_RS12650	COG3584	3D domain protein
H4K32_RS12655	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H4K32_RS12665	COG2056	Na+-H+ antiporter family
H4K32_RS12670	COG1268	BioY protein
H4K32_RS12675	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H4K32_RS12680	COG2819	hydrolase of the alpha beta superfamily
H4K32_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS12690	COG1169	isochorismate synthase
H4K32_RS12695	COG1021	2,3-dihydroxybenzoate-AMP ligase
H4K32_RS12700	COG3433	isochorismatase activity
H4K32_RS12700	COG1535	isochorismatase
H4K32_RS12705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS12710	COG3251	PFAM MbtH domain protein
H4K32_RS12715	COG5634	Uncharacterized conserved protein (DUF2278)
H4K32_RS12720	COG0686	Belongs to the AlaDH PNT family
H4K32_RS12725	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H4K32_RS12725	COG2508	Transcriptional regulator
H4K32_RS12730	COG4842	Belongs to the WXG100 family
H4K32_RS12735	COG5417	Belongs to the EsaB family
H4K32_RS12740	COG4499	WXG100 protein secretion system (Wss), protein YukC
H4K32_RS12745	COG1674	ftsk spoiiie
H4K32_RS12745	COG0433	COG0433 Predicted ATPase
H4K32_RS12750	COG1511	domain protein
H4K32_RS12760	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS12765	COG1418	mRNA catabolic process
H4K32_RS12775	COG0628	permease
H4K32_RS12790	COG5506	Protein of unknown function (DUF1694)
H4K32_RS12795	COG1335	isochorismatase
H4K32_RS12800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H4K32_RS12805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H4K32_RS12820	COG0142	geranyltranstransferase activity
H4K32_RS12830	COG4585	Histidine kinase
H4K32_RS12835	COG2197	response regulator
H4K32_RS12840	COG2050	protein possibly involved in aromatic compounds catabolism
H4K32_RS12845	COG1320	monovalent cation:proton antiporter activity
H4K32_RS12850	COG2212	antiporter activity
H4K32_RS12855	COG1863	multisubunit Na H antiporter MnhE subunit
H4K32_RS12860	COG0651	ATP synthesis coupled electron transport
H4K32_RS12865	COG1006	Multisubunit Na H antiporter MnhC subunit
H4K32_RS12870	COG2111	Na H antiporter
H4K32_RS12875	COG2111	Na H antiporter
H4K32_RS12875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H4K32_RS12905	COG4565	transcriptional regulatory protein
H4K32_RS12910	COG3290	protein histidine kinase activity
H4K32_RS12920	COG3011	Protein conserved in bacteria
H4K32_RS12925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H4K32_RS12930	COG2814	Major facilitator Superfamily
H4K32_RS12935	COG5018	Exonuclease
H4K32_RS12945	COG2205	protein histidine kinase activity
H4K32_RS12950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H4K32_RS12960	COG2267	carboxylic ester hydrolase activity
H4K32_RS12965	COG1522	sequence-specific DNA binding
H4K32_RS12970	COG0436	Aminotransferase
H4K32_RS12975	COG1098	S1 RNA binding domain
H4K32_RS12980	COG2155	Conserved Protein
H4K32_RS12985	COG1979	alcohol dehydrogenase
H4K32_RS12990	COG1979	alcohol dehydrogenase
H4K32_RS12995	COG1335	isochorismatase
H4K32_RS13025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H4K32_RS13040	COG2738	Putative neutral zinc metallopeptidase
H4K32_RS13045	COG1253	flavin adenine dinucleotide binding
H4K32_RS13050	COG0366	Alpha amylase catalytic
H4K32_RS13055	COG0432	Pfam Uncharacterised protein family UPF0047
H4K32_RS13060	COG2070	2-Nitropropane dioxygenase
H4K32_RS13075	COG0840	transmembrane signaling receptor activity
H4K32_RS13080	COG0840	transmembrane signaling receptor activity
H4K32_RS13085	COG0840	transmembrane signaling receptor activity
H4K32_RS13090	COG0840	transmembrane signaling receptor activity
H4K32_RS13095	COG0693	protein deglycase activity
H4K32_RS13100	COG0673	inositol 2-dehydrogenase activity
H4K32_RS13105	COG0628	permease
H4K32_RS13145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H4K32_RS13145	COG1017	nitric oxide dioxygenase activity
H4K32_RS13150	COG1705	Flagellar rod assembly protein muramidase FlgJ
H4K32_RS13155	COG0569	domain protein
H4K32_RS13165	COG1510	regulation of RNA biosynthetic process
H4K32_RS13170	COG1012	belongs to the aldehyde dehydrogenase family
H4K32_RS13175	COG1454	alcohol dehydrogenase
H4K32_RS13185	COG2318	DinB family
H4K32_RS13190	COG1585	Membrane protein implicated in regulation of membrane protease activity
H4K32_RS13195	COG2268	Band 7 protein
H4K32_RS13200	COG3859	Proton-coupled thiamine transporter YuaJ
H4K32_RS13325	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
H4K32_RS13330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H4K32_RS13335	COG1169	isochorismate synthase
H4K32_RS13345	COG0596	Alpha beta hydrolase
H4K32_RS13350	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H4K32_RS13360	COG4948	Mandelate Racemase Muconate Lactonizing
H4K32_RS13370	COG1294	oxidase, subunit
H4K32_RS13375	COG1271	oxidase subunit
H4K32_RS13385	COG0288	reversible hydration of carbon dioxide
H4K32_RS13410	COG0783	Belongs to the Dps family
H4K32_RS13415	COG4824	toxin secretion phage lysis holin
H4K32_RS13420	COG0494	nUDIX hydrolase
H4K32_RS13425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H4K32_RS13430	COG1116	anion transmembrane transporter activity
H4K32_RS13435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H4K32_RS13440	COG1506	peptidase
H4K32_RS13460	COG0367	asparagine synthase
H4K32_RS13465	COG1113	amino acid transport
H4K32_RS13470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H4K32_RS13475	COG2267	carboxylic ester hydrolase activity
H4K32_RS13485	COG0584	glycerophosphoryl diester phosphodiesterase
H4K32_RS13495	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H4K32_RS13500	COG1242	4 iron, 4 sulfur cluster binding
H4K32_RS13510	COG1725	Transcriptional regulator
H4K32_RS13515	COG1131	(ABC) transporter
H4K32_RS13535	COG1136	(ABC) transporter
H4K32_RS13540	COG0577	efflux transmembrane transporter activity
H4K32_RS13545	COG0745	RESPONSE REGULATOR receiver
H4K32_RS13550	COG2205	protein histidine kinase activity
H4K32_RS13555	COG1136	(ABC) transporter
H4K32_RS13560	COG0577	efflux transmembrane transporter activity
H4K32_RS13565	COG5522	Integral membrane protein (intg_mem_TP0381)
H4K32_RS13570	COG2814	Major facilitator Superfamily
H4K32_RS13575	COG1366	Belongs to the anti-sigma-factor antagonist family
H4K32_RS13575	COG2202	Pas domain
H4K32_RS13590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H4K32_RS13600	COG1486	melibiose metabolic process
H4K32_RS13605	COG0395	ABC-type sugar transport system, permease component
H4K32_RS13610	COG1175	transmembrane transport
H4K32_RS13615	COG1653	transport
H4K32_RS13620	COG1609	Transcriptional regulator
H4K32_RS13630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H4K32_RS13635	COG2081	HI0933 family
H4K32_RS13640	COG2244	polysaccharide biosynthetic process
H4K32_RS13645	COG1187	pseudouridine synthase activity
H4K32_RS13650	COG1349	DNA-binding transcription factor activity
H4K32_RS13655	COG1131	(ABC) transporter
H4K32_RS13660	COG4473	ABC transporter
H4K32_RS13665	COG2252	PERMEase
H4K32_RS13670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H4K32_RS13675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H4K32_RS13680	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H4K32_RS13690	COG1597	lipid kinase activity
H4K32_RS13695	COG0510	thiamine kinase activity
H4K32_RS13710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4K32_RS13715	COG0281	malic enzyme
H4K32_RS13720	COG5584	Small secreted protein
H4K32_RS13725	COG1363	Peptidase, m42
H4K32_RS13735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H4K32_RS13745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H4K32_RS13750	COG1674	ftsk spoiiie
H4K32_RS13760	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H4K32_RS13765	COG4980	gas vesicle protein
H4K32_RS13770	COG3118	belongs to the thioredoxin family
H4K32_RS13775	COG1605	Chorismate mutase
H4K32_RS13775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H4K32_RS13780	COG1609	Transcriptional regulator
H4K32_RS13785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H4K32_RS13790	COG1360	Flagellar Motor Protein
H4K32_RS13795	COG0123	including yeast histone deacetylase and acetoin utilization protein
H4K32_RS13800	COG0517	IMP dehydrogenase activity
H4K32_RS13805	COG0454	-acetyltransferase
H4K32_RS13810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H4K32_RS13830	COG1378	Sugar-specific transcriptional regulator TrmB
H4K32_RS13835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H4K32_RS13850	COG0693	protein deglycase activity
H4K32_RS13860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H4K32_RS13860	COG1017	nitric oxide dioxygenase activity
H4K32_RS13895	COG2203	Gaf domain
H4K32_RS13895	COG2199	diguanylate cyclase activity
H4K32_RS13900	COG1956	GAF domain-containing protein
H4K32_RS13905	COG1309	transcriptional regulator
H4K32_RS13910	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H4K32_RS13920	COG1114	Component of the transport system for branched-chain amino acids
H4K32_RS13925	COG1104	cysteine desulfurase activity
H4K32_RS13940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H4K32_RS13945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H4K32_RS13950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H4K32_RS13955	COG0616	signal peptide processing
H4K32_RS13960	COG1714	RDD family
H4K32_RS13970	COG3874	Sporulation protein YtfJ
H4K32_RS13975	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H4K32_RS13980	COG0827	DNA restriction-modification system
H4K32_RS13990	COG0521	Mo-molybdopterin cofactor biosynthetic process
H4K32_RS14005	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS14015	COG4109	DRTGG domain
H4K32_RS14025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H4K32_RS14045	COG0587	DNA-directed DNA polymerase activity
H4K32_RS14050	COG0281	malic enzyme
H4K32_RS14070	COG0469	pyruvate kinase activity
H4K32_RS14075	COG3030	protein affecting phage T7 exclusion by the F plasmid
H4K32_RS14080	COG0628	permease
H4K32_RS14100	COG0372	Belongs to the citrate synthase family
H4K32_RS14105	COG0538	isocitrate dehydrogenase activity
H4K32_RS14115	COG0745	RESPONSE REGULATOR receiver
H4K32_RS14120	COG5002	protein histidine kinase activity
H4K32_RS14125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H4K32_RS14125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H4K32_RS14130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H4K32_RS14135	COG1971	Probably functions as a manganese efflux pump
H4K32_RS14140	COG0237	dephospho-CoA kinase activity
H4K32_RS14145	COG0656	L-ascorbic acid biosynthetic process
H4K32_RS14150	COG2814	Major facilitator Superfamily
H4K32_RS14155	COG1733	regulation of RNA biosynthetic process
H4K32_RS14160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H4K32_RS14175	COG3611	Membrane attachment protein
H4K32_RS14180	COG1484	DNA-dependent DNA replication
H4K32_RS14185	COG0398	Pfam SNARE associated Golgi protein
H4K32_RS14200	COG1011	Hydrolase
H4K32_RS14205	COG3275	phosphorelay sensor kinase activity
H4K32_RS14210	COG3279	Response regulator of the LytR AlgR family
H4K32_RS14215	COG1380	Effector of murein hydrolase LrgA
H4K32_RS14220	COG1346	cytolysis
H4K32_RS14225	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H4K32_RS14235	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H4K32_RS14240	COG3326	Membrane
H4K32_RS14250	COG1363	Peptidase, m42
H4K32_RS14255	COG3507	Belongs to the glycosyl hydrolase 43 family
H4K32_RS14260	COG2160	L-arabinose isomerase activity
H4K32_RS14265	COG1069	ribulokinase activity
H4K32_RS14270	COG0235	Class ii aldolase
H4K32_RS14275	COG0647	UMP catabolic process
H4K32_RS14285	COG1653	transport
H4K32_RS14290	COG1175	transmembrane transport
H4K32_RS14295	COG0395	ABC-type sugar transport system, permease component
H4K32_RS14300	COG3534	alpha-L-arabinofuranosidase
H4K32_RS14305	COG1966	Carbon starvation protein
H4K32_RS14310	COG0247	lactate metabolic process
H4K32_RS14315	COG0277	FAD linked oxidase domain protein
H4K32_RS14320	COG3835	regulator
H4K32_RS14330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H4K32_RS14335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H4K32_RS14340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H4K32_RS14340	COG0072	phenylalanine-tRNA ligase activity
H4K32_RS14355	COG1286	toxin biosynthetic process
H4K32_RS14360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H4K32_RS14360	COG1796	DNA polymerase
H4K32_RS14370	COG3766	membrane
H4K32_RS14380	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS14385	COG1309	transcriptional regulator
H4K32_RS14390	COG1024	Enoyl-CoA hydratase
H4K32_RS14395	COG2086	electron transfer activity
H4K32_RS14400	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H4K32_RS14405	COG3534	alpha-L-arabinofuranosidase
H4K32_RS14410	COG3118	belongs to the thioredoxin family
H4K32_RS14420	COG0527	aspartate kinase activity
H4K32_RS14425	COG1719	4-vinyl reductase, 4VR
H4K32_RS14430	COG2009	succinate dehydrogenase
H4K32_RS14435	COG1053	succinate dehydrogenase
H4K32_RS14440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H4K32_RS14445	COG0824	Thioesterase
H4K32_RS14450	COG2197	response regulator
H4K32_RS14455	COG1846	Transcriptional regulator
H4K32_RS14465	COG5401	PFAM Sporulation and spore germination
H4K32_RS14475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H4K32_RS14480	COG0622	Phosphoesterase
H4K32_RS14505	COG0028	Belongs to the TPP enzyme family
H4K32_RS14510	COG0440	acetolactate synthase activity
H4K32_RS14525	COG0473	3-isopropylmalate dehydrogenase activity
H4K32_RS14540	COG1477	protein flavinylation
H4K32_RS14540	COG0457	Tetratricopeptide repeat
H4K32_RS14555	COG0470	DNA polymerase III
H4K32_RS14555	COG1067	ATP-dependent peptidase activity
H4K32_RS14560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H4K32_RS14580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H4K32_RS14590	COG1587	Uroporphyrinogen-III synthase
H4K32_RS14595	COG0113	porphobilinogen synthase activity
H4K32_RS14605	COG1388	LysM domain
H4K32_RS14610	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H4K32_RS14620	COG0525	valine-tRNA ligase activity
H4K32_RS14625	COG0285	dihydrofolate synthase activity
H4K32_RS14630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H4K32_RS14650	COG1077	Cell shape determining protein MreB Mrl
H4K32_RS14660	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H4K32_RS14670	COG2894	cell division
H4K32_RS14675	COG0739	heme binding
H4K32_RS14680	COG1994	Peptidase M50
H4K32_RS14690	COG2868	ribosomal protein
H4K32_RS14695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H4K32_RS14700	COG3290	protein histidine kinase activity
H4K32_RS14715	COG0077	Prephenate dehydratase
H4K32_RS14720	COG1827	regulation of RNA biosynthetic process
H4K32_RS14725	COG1104	cysteine desulfurase activity
H4K32_RS14730	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H4K32_RS14735	COG0157	Belongs to the NadC ModD family
H4K32_RS14745	COG1388	LysM domain
H4K32_RS14790	COG1862	Preprotein translocase
H4K32_RS14800	COG2323	membrane
H4K32_RS14805	COG2244	polysaccharide biosynthetic process
H4K32_RS14815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H4K32_RS14815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H4K32_RS14820	COG0490	domain, Protein
H4K32_RS14825	COG5416	Lipopolysaccharide assembly protein A domain
H4K32_RS14830	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H4K32_RS14830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H4K32_RS14840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H4K32_RS14850	COG0860	N-Acetylmuramoyl-L-alanine amidase
H4K32_RS14850	COG3103	Sh3 type 3 domain protein
H4K32_RS14850	COG4991	sh3 domain protein
H4K32_RS14875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H4K32_RS14880	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H4K32_RS14885	COG1959	2 iron, 2 sulfur cluster binding
H4K32_RS14890	COG1104	cysteine desulfurase activity
H4K32_RS14900	COG0457	Tetratricopeptide repeat
H4K32_RS14905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H4K32_RS14910	COG3881	PFAM PRC-barrel domain
H4K32_RS14925	COG0765	amino acid transport
H4K32_RS14930	COG0765	amino acid transport
H4K32_RS14935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H4K32_RS14940	COG1126	abc transporter atp-binding protein
H4K32_RS14945	COG0628	permease
H4K32_RS14955	COG4472	Bacterial protein of unknown function (DUF965)
H4K32_RS14970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H4K32_RS14975	COG4122	O-methyltransferase activity
H4K32_RS15000	COG0768	penicillin binding
H4K32_RS15025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H4K32_RS15030	COG0626	cystathionine gamma-synthase activity
H4K32_RS15040	COG2427	Protein of unknown function (DUF1641)
H4K32_RS15045	COG3383	formate dehydrogenase (NAD+) activity
H4K32_RS15050	COG5609	conserved protein (DUF2294)
H4K32_RS15055	COG2116	formate transmembrane transporter activity
H4K32_RS15070	COG2226	methyltransferase
H4K32_RS15075	COG1309	transcriptional regulator
H4K32_RS15080	COG2124	cytochrome p450
H4K32_RS15080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H4K32_RS15085	COG2814	Major facilitator Superfamily
H4K32_RS15090	COG0583	DNA-binding transcription factor activity
H4K32_RS15095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H4K32_RS15105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H4K32_RS15105	COG3711	transcriptional antiterminator
H4K32_RS15110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H4K32_RS15110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H4K32_RS15110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H4K32_RS15115	COG1482	cell wall glycoprotein biosynthetic process
H4K32_RS15125	COG0561	phosphatase activity
H4K32_RS15130	COG0561	phosphatase activity
H4K32_RS15140	COG2318	DinB family
H4K32_RS15145	COG0456	acetyltransferase
H4K32_RS15155	COG2814	Major facilitator Superfamily
H4K32_RS15160	COG0563	adenylate kinase activity
H4K32_RS15210	COG0398	Pfam SNARE associated Golgi protein
H4K32_RS15220	COG2755	lipolytic protein G-D-S-L family
H4K32_RS15230	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H4K32_RS15235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H4K32_RS15240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H4K32_RS15245	COG1534	Rna-binding protein
H4K32_RS15255	COG1713	HD superfamily hydrolase involved in NAD metabolism
H4K32_RS15260	COG0799	negative regulation of ribosome biogenesis
H4K32_RS15265	COG2226	methyltransferase
H4K32_RS15270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H4K32_RS15275	COG1596	polysaccharide export
H4K32_RS15275	COG1555	photosystem II stabilization
H4K32_RS15280	COG2131	deaminase
H4K32_RS15285	COG2333	competence protein COMEC
H4K32_RS15285	COG0658	competence protein
H4K32_RS15300	COG1466	dna polymerase III delta subunit
H4K32_RS15315	COG0860	N-Acetylmuramoyl-L-alanine amidase
H4K32_RS15330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H4K32_RS15360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H4K32_RS15365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H4K32_RS15370	COG1283	sodium-dependent phosphate transmembrane transporter activity
H4K32_RS15380	COG1610	YqeY-like protein
H4K32_RS15385	COG1030	water channel activity
H4K32_RS15390	COG4864	UPF0365 protein
H4K32_RS15405	COG0561	phosphatase activity
H4K32_RS15410	COG1702	phosphate starvation-inducible protein PhoH
H4K32_RS15415	COG1480	7TM receptor with intracellular HD hydrolase
H4K32_RS15425	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H4K32_RS15430	COG0295	cytidine deaminase activity
H4K32_RS15435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H4K32_RS15455	COG0751	glycine-tRNA ligase activity
H4K32_RS15460	COG0517	IMP dehydrogenase activity
H4K32_RS15475	COG0358	DNA primase activity
H4K32_RS15480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H4K32_RS15485	COG2010	Cytochrome c
H4K32_RS15490	COG2384	SAM-dependent methyltransferase
H4K32_RS15495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H4K32_RS15510	COG0513	Belongs to the DEAD box helicase family
H4K32_RS15525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H4K32_RS15530	COG0735	belongs to the Fur family
H4K32_RS15535	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
H4K32_RS15540	COG4709	membrane
H4K32_RS15550	COG1388	LysM domain
H4K32_RS15555	COG5521	maltodextrose utilization protein MalA
H4K32_RS15560	COG2839	Protein conserved in bacteria
H4K32_RS15565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H4K32_RS15570	COG0477	Major facilitator Superfamily
H4K32_RS15580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H4K32_RS15585	COG0573	inorganic phosphate transmembrane transporter activity
H4K32_RS15590	COG0581	inorganic phosphate transmembrane transporter activity
H4K32_RS15595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H4K32_RS15600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H4K32_RS15605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H4K32_RS15620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H4K32_RS15630	COG1757	Na H antiporter
H4K32_RS15635	COG4483	Protein conserved in bacteria
H4K32_RS15640	COG1940	carbohydrate kinase activity
H4K32_RS15645	COG2866	Carboxypeptidase
H4K32_RS15655	COG0011	TIGRFAM Protein of
H4K32_RS15665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4K32_RS15675	COG1393	Belongs to the ArsC family
H4K32_RS15685	COG1366	Belongs to the anti-sigma-factor antagonist family
H4K32_RS15690	COG1253	flavin adenine dinucleotide binding
H4K32_RS15695	COG0598	Magnesium transport protein CorA
H4K32_RS15700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H4K32_RS15705	COG1459	type II secretion system
H4K32_RS15710	COG4537	Required for transformation and DNA binding
H4K32_RS15715	COG4970	Tfp pilus assembly protein FimT
H4K32_RS15725	COG4940	Competence protein ComGF
H4K32_RS15750	COG0681	Belongs to the peptidase S26 family
H4K32_RS15760	COG1396	sequence-specific DNA binding
H4K32_RS15775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H4K32_RS15795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H4K32_RS15810	COG1752	Esterase of the alpha-beta hydrolase superfamily
H4K32_RS15820	COG3872	metal-dependent enzyme
H4K32_RS15830	COG0006	proline dipeptidase activity
H4K32_RS15845	COG3854	ATPases associated with a variety of cellular activities
H4K32_RS15885	COG0511	ligase activity, forming carbon-carbon bonds
H4K32_RS15890	COG0439	Biotin carboxylase
H4K32_RS15895	COG1302	Protein conserved in bacteria
H4K32_RS15910	COG1570	exodeoxyribonuclease VII activity
H4K32_RS15920	COG0142	geranyltranstransferase activity
H4K32_RS15930	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H4K32_RS15940	COG0497	DNA recombination
H4K32_RS15945	COG0750	zinc metalloprotease
H4K32_RS15950	COG0745	RESPONSE REGULATOR receiver
H4K32_RS15955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H4K32_RS15970	COG1902	pentaerythritol trinitrate reductase activity
H4K32_RS15995	COG0860	N-Acetylmuramoyl-L-alanine amidase
H4K32_RS16000	COG0584	glycerophosphoryl diester phosphodiesterase
H4K32_RS16005	COG0183	Belongs to the thiolase family
H4K32_RS16010	COG1250	3-hydroxyacyl-CoA dehydrogenase
H4K32_RS16015	COG1960	acyl-CoA dehydrogenase activity
H4K32_RS16020	COG0372	Belongs to the citrate synthase family
H4K32_RS16025	COG2079	MmgE PrpD family protein
H4K32_RS16030	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H4K32_RS16040	COG3829	transcription factor binding
H4K32_RS16040	COG3290	protein histidine kinase activity
H4K32_RS16045	COG0280	phosphate acetyltransferase
H4K32_RS16050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H4K32_RS16055	COG3426	butyrate kinase activity
H4K32_RS16060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H4K32_RS16065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H4K32_RS16070	COG0022	dehydrogenase e1 component
H4K32_RS16075	COG0508	dehydrogenase complex catalyzes the overall conversion of
H4K32_RS16080	COG1597	lipid kinase activity
H4K32_RS16090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H4K32_RS16095	COG0765	amino acid transport
H4K32_RS16100	COG1126	abc transporter atp-binding protein
H4K32_RS16105	COG4129	membrane
H4K32_RS16110	COG1376	ErfK ybiS ycfS ynhG family protein
H4K32_RS16120	COG0346	lactoylglutathione lyase activity
H4K32_RS16125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H4K32_RS16130	COG2195	Cleaves the N-terminal amino acid of tripeptides
H4K32_RS16135	COG0706	membrane insertase activity
H4K32_RS16150	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H4K32_RS16155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H4K32_RS16170	COG0596	Alpha beta hydrolase
H4K32_RS16190	COG0250	Participates in transcription elongation, termination and antitermination
H4K32_RS16195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H4K32_RS16195	COG2070	2-Nitropropane dioxygenase
H4K32_RS16210	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS16215	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS16220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS16220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS16220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS16220	COG3321	synthase
H4K32_RS16225	COG0300	oxidoreductase activity
H4K32_RS16225	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS16225	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS16225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS16225	COG3321	synthase
H4K32_RS16230	COG3321	synthase
H4K32_RS16230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS16230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS16230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS16230	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS16235	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS16235	COG3321	synthase
H4K32_RS16235	COG0300	oxidoreductase activity
H4K32_RS16235	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS16235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS16240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS16240	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS16240	COG0300	oxidoreductase activity
H4K32_RS16240	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS16240	COG3321	synthase
H4K32_RS16245	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS16245	COG3321	synthase
H4K32_RS16245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS16245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS16245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS16250	COG3321	synthase
H4K32_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS16250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS16250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS16250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS16255	COG2124	cytochrome p450
H4K32_RS16260	COG3425	synthase
H4K32_RS16265	COG1024	Enoyl-CoA hydratase
H4K32_RS16270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H4K32_RS16275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4K32_RS16280	COG0300	oxidoreductase activity
H4K32_RS16285	COG3048	D-serine ammonia-lyase activity
H4K32_RS16295	COG0346	lactoylglutathione lyase activity
H4K32_RS16305	COG0628	permease
H4K32_RS16320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H4K32_RS16325	COG0456	acetyltransferase
H4K32_RS16330	COG2329	Antibiotic biosynthesis monooxygenase
H4K32_RS16335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H4K32_RS16335	COG0456	acetyltransferase
H4K32_RS16340	COG4918	Iron-sulphur cluster biosynthesis
H4K32_RS16350	COG1073	alpha beta
H4K32_RS16360	COG0667	Aldo Keto reductase
H4K32_RS16370	COG0494	nUDIX hydrolase
H4K32_RS16375	COG1379	DNA repair
H4K32_RS16380	COG1396	sequence-specific DNA binding
H4K32_RS16385	COG0252	asparaginase activity
H4K32_RS16390	COG1027	Aspartate ammonia-lyase
H4K32_RS16395	COG1757	Na H antiporter
H4K32_RS16400	COG0281	malic enzyme
H4K32_RS16415	COG1300	Membrane
H4K32_RS16420	COG0735	belongs to the Fur family
H4K32_RS16430	COG4974	Belongs to the 'phage' integrase family
H4K32_RS16435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H4K32_RS16440	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H4K32_RS16445	COG1686	Belongs to the peptidase S11 family
H4K32_RS16450	COG1366	Belongs to the anti-sigma-factor antagonist family
H4K32_RS16460	COG1191	sigma factor activity
H4K32_RS16480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H4K32_RS16495	COG0697	spore germination
H4K32_RS16500	COG0019	diaminopimelate decarboxylase activity
H4K32_RS16505	COG4086	secreted protein
H4K32_RS16510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H4K32_RS16520	COG0681	Belongs to the peptidase S26 family
H4K32_RS16530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H4K32_RS16530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H4K32_RS16535	COG0307	riboflavin synthase, alpha
H4K32_RS16550	COG0456	acetyltransferase
H4K32_RS16555	COG1547	Domain of unknown function (DUF309)
H4K32_RS16580	COG1686	Belongs to the peptidase S11 family
H4K32_RS16585	COG2715	membrane protein required for spore maturation
H4K32_RS16590	COG0700	Nucleoside recognition
H4K32_RS16595	COG1187	pseudouridine synthase activity
H4K32_RS16600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H4K32_RS16605	COG1333	cytochrome c biogenesis protein
H4K32_RS16610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H4K32_RS16615	COG0745	RESPONSE REGULATOR receiver
H4K32_RS16620	COG5002	protein histidine kinase activity
H4K32_RS16625	COG1595	DNA-templated transcription, initiation
H4K32_RS16635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H4K32_RS16640	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H4K32_RS16645	COG1141	Ferredoxin
H4K32_RS16650	COG4955	Helix-turn-helix domain
H4K32_RS16655	COG0514	ATP-dependent DNA helicase (RecQ)
H4K32_RS16660	COG1266	CAAX protease self-immunity
H4K32_RS16665	COG1388	LysM domain
H4K32_RS16675	COG1408	metallophosphoesterase
H4K32_RS16680	COG4862	establishment of competence for transformation
H4K32_RS16685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H4K32_RS16690	COG0492	ferredoxin-NADP+ reductase activity
H4K32_RS16695	COG2339	peptidase activity
H4K32_RS16700	COG3773	Cell wall hydrolase
H4K32_RS16700	COG3409	Peptidoglycan-binding domain 1 protein
H4K32_RS16705	COG2959	enzyme of heme biosynthesis
H4K32_RS16710	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H4K32_RS16725	COG0539	negative regulation of cytoplasmic translation
H4K32_RS16765	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H4K32_RS16770	COG0776	regulation of translation
H4K32_RS16785	COG0142	geranyltranstransferase activity
H4K32_RS16795	COG0142	geranyltranstransferase activity
H4K32_RS16800	COG0105	UTP biosynthetic process
H4K32_RS16805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H4K32_RS16820	COG4401	Chorismate mutase type I
H4K32_RS16825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H4K32_RS16860	COG0287	Prephenate dehydrogenase
H4K32_RS16870	COG0457	Tetratricopeptide repeat
H4K32_RS16885	COG0723	plastoquinol--plastocyanin reductase activity
H4K32_RS16890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H4K32_RS16895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H4K32_RS16895	COG2010	Cytochrome c
H4K32_RS16900	COG4347	Protein of unknown function (DUF1405)
H4K32_RS16910	COG2140	Oxalate decarboxylase
H4K32_RS16915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H4K32_RS16920	COG1694	Mazg nucleotide pyrophosphohydrolase
H4K32_RS16935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H4K32_RS16940	COG0438	transferase activity, transferring glycosyl groups
H4K32_RS16970	COG1199	ATP-dependent helicase activity
H4K32_RS16970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H4K32_RS16980	COG5353	protein conserved in bacteria
H4K32_RS16985	COG0436	Aminotransferase
H4K32_RS16995	COG3935	DnaD domain protein
H4K32_RS17000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H4K32_RS17010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H4K32_RS17010	COG4499	WXG100 protein secretion system (Wss), protein YukC
H4K32_RS17050	COG0071	Belongs to the small heat shock protein (HSP20) family
H4K32_RS17055	COG2190	(PTS) system
H4K32_RS17060	COG1111	helicase
H4K32_RS17060	COG1205	dead DEAH box helicase
H4K32_RS17065	COG3359	exonuclease
H4K32_RS17095	COG0116	Belongs to the methyltransferase superfamily
H4K32_RS17110	COG1199	ATP-dependent helicase activity
H4K32_RS17115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H4K32_RS17125	COG2233	PERMEase
H4K32_RS17135	COG1335	isochorismatase
H4K32_RS17160	COG3424	synthase
H4K32_RS17165	COG1755	Isoprenylcysteine carboxyl methyltransferase
H4K32_RS17175	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H4K32_RS17190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H4K32_RS17200	COG0328	RNA-DNA hybrid ribonuclease activity
H4K32_RS17205	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H4K32_RS17210	COG0328	RNA-DNA hybrid ribonuclease activity
H4K32_RS17230	COG1278	Cold shock
H4K32_RS17240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H4K32_RS17250	COG0386	Belongs to the glutathione peroxidase family
H4K32_RS17255	COG1418	mRNA catabolic process
H4K32_RS17260	COG1413	lyase activity
H4K32_RS17275	COG2521	methyltransferase
H4K32_RS17275	COG2136	Putative SAM-dependent methyltransferase
H4K32_RS17290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H4K32_RS17295	COG0204	Acyl-transferase
H4K32_RS17300	COG1272	protein, Hemolysin III
H4K32_RS17305	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H4K32_RS17310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H4K32_RS17320	COG1999	signal sequence binding
H4K32_RS17325	COG2755	lipolytic protein G-D-S-L family
H4K32_RS17330	COG4698	Protein conserved in bacteria
H4K32_RS17335	COG1846	Transcriptional regulator
H4K32_RS17355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H4K32_RS17365	COG4282	regulation of fungal-type cell wall biogenesis
H4K32_RS17370	COG5444	nuclease activity
H4K32_RS17385	COG3391	amine dehydrogenase activity
H4K32_RS17405	COG1388	LysM domain
H4K32_RS17425	COG1086	Polysaccharide biosynthesis protein
H4K32_RS17435	COG4641	Protein conserved in bacteria
H4K32_RS17450	COG0463	Glycosyl transferase, family 2
H4K32_RS17455	COG0456	acetyltransferase
H4K32_RS17465	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H4K32_RS17470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H4K32_RS17475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H4K32_RS17480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H4K32_RS17485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H4K32_RS17490	COG0456	acetyltransferase
H4K32_RS17495	COG1509	lysine 2,3-aminomutase activity
H4K32_RS17530	COG0671	phosphoesterase, PA-phosphatase related
H4K32_RS17550	COG1876	peptidase activity
H4K32_RS17560	COG2226	methyltransferase
H4K32_RS17565	COG3409	Peptidoglycan-binding domain 1 protein
H4K32_RS17565	COG0793	Belongs to the peptidase S41A family
H4K32_RS17570	COG2188	Transcriptional regulator
H4K32_RS17575	COG2723	6-phospho-beta-galactosidase activity
H4K32_RS17585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H4K32_RS17595	COG0346	lactoylglutathione lyase activity
H4K32_RS17600	COG0400	carboxylic ester hydrolase activity
H4K32_RS17605	COG0778	Nitroreductase
H4K32_RS17610	COG1733	regulation of RNA biosynthetic process
H4K32_RS17620	COG1942	4-Oxalocrotonate Tautomerase
H4K32_RS17635	COG2962	Rard protein
H4K32_RS17645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H4K32_RS17650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H4K32_RS17655	COG1366	Belongs to the anti-sigma-factor antagonist family
H4K32_RS17660	COG0534	Mate efflux family protein
H4K32_RS17665	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H4K32_RS17670	COG1819	glycosyl
H4K32_RS17675	COG0791	NLP P60 protein
H4K32_RS17675	COG1388	LysM domain
H4K32_RS17680	COG2032	superoxide dismutase activity
H4K32_RS17685	COG0714	Associated with various cellular activities
H4K32_RS17690	COG4548	von Willebrand factor, type A
H4K32_RS17700	COG0508	dehydrogenase complex catalyzes the overall conversion of
H4K32_RS17705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4K32_RS17710	COG0385	Bile acid
H4K32_RS17715	COG0733	neurotransmitter:sodium symporter activity
H4K32_RS17720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H4K32_RS17725	COG1657	PFAM Prenyltransferase squalene oxidase
H4K32_RS17730	COG1012	belongs to the aldehyde dehydrogenase family
H4K32_RS17760	COG0071	Belongs to the small heat shock protein (HSP20) family
H4K32_RS17775	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H4K32_RS17780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H4K32_RS17790	COG0514	ATP-dependent DNA helicase (RecQ)
H4K32_RS17795	COG3584	3D domain protein
H4K32_RS17795	COG1388	LysM domain
H4K32_RS17820	COG2322	membrane
H4K32_RS17825	COG0741	lytic transglycosylase activity
H4K32_RS17830	COG0640	Transcriptional regulator
H4K32_RS17840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4K32_RS17845	COG1309	transcriptional regulator
H4K32_RS17850	COG0662	Cupin 2, conserved barrel domain protein
H4K32_RS17850	COG2207	Transcriptional regulator
H4K32_RS17855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H4K32_RS17860	COG1733	regulation of RNA biosynthetic process
H4K32_RS17865	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS17885	COG0243	molybdopterin cofactor binding
H4K32_RS17890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H4K32_RS17895	COG1070	Carbohydrate kinase
H4K32_RS17900	COG2814	Major facilitator Superfamily
H4K32_RS17910	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H4K32_RS17915	COG0300	oxidoreductase activity
H4K32_RS17930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H4K32_RS17935	COG0583	DNA-binding transcription factor activity
H4K32_RS17940	COG0067	glutamate synthase
H4K32_RS17940	COG0069	glutamate synthase activity
H4K32_RS17940	COG0070	glutamate synthase
H4K32_RS17945	COG0493	'glutamate synthase
H4K32_RS17950	COG0604	alcohol dehydrogenase
H4K32_RS17965	COG0640	Transcriptional regulator
H4K32_RS17970	COG2814	Major facilitator Superfamily
H4K32_RS17975	COG0405	Gamma-glutamyltransferase
H4K32_RS17980	COG0166	Belongs to the GPI family
H4K32_RS17985	COG0582	viral genome integration into host DNA
H4K32_RS18000	COG0534	Mate efflux family protein
H4K32_RS18005	COG2017	converts alpha-aldose to the beta-anomer
H4K32_RS18010	COG2027	D-alanyl-D-alanine carboxypeptidase
H4K32_RS18015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS18020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS18025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS18030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS18035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS18035	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H4K32_RS18045	COG1649	PFAM Uncharacterised BCR, COG1649
H4K32_RS18050	COG1960	acyl-CoA dehydrogenase activity
H4K32_RS18055	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS18060	COG0439	Biotin carboxylase
H4K32_RS18065	COG0511	ligase activity, forming carbon-carbon bonds
H4K32_RS18070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H4K32_RS18075	COG1024	Enoyl-CoA hydratase
H4K32_RS18080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H4K32_RS18085	COG0586	Pfam SNARE associated Golgi protein
H4K32_RS18090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H4K32_RS18095	COG2246	polysaccharide biosynthetic process
H4K32_RS18105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H4K32_RS18125	COG2124	cytochrome p450
H4K32_RS18130	COG2610	gluconate transmembrane transporter activity
H4K32_RS18135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H4K32_RS18140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H4K32_RS18145	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS18170	COG3507	Belongs to the glycosyl hydrolase 43 family
H4K32_RS18180	COG0745	RESPONSE REGULATOR receiver
H4K32_RS18185	COG2205	protein histidine kinase activity
H4K32_RS18225	COG1609	Transcriptional regulator
H4K32_RS18230	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS18235	COG1312	Catalyzes the dehydration of D-mannonate
H4K32_RS18240	COG0800	Aldolase
H4K32_RS18245	COG1063	alcohol dehydrogenase
H4K32_RS18255	COG1115	amino acid carrier protein
H4K32_RS18265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H4K32_RS18270	COG0187	DNA topoisomerase II activity
H4K32_RS18275	COG1832	CoA-binding protein
H4K32_RS18285	COG4841	protein insertion into membrane
H4K32_RS18295	COG0824	Thioesterase
H4K32_RS18315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H4K32_RS18320	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H4K32_RS18335	COG0071	Belongs to the small heat shock protein (HSP20) family
H4K32_RS18345	COG4846	Membrane protein involved in cytochrome C biogenesis
H4K32_RS18350	COG2201	protein-glutamate methylesterase activity
H4K32_RS18355	COG0785	Cytochrome C biogenesis protein
H4K32_RS18375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H4K32_RS18385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H4K32_RS18420	COG4195	phage-related replication protein
H4K32_RS18425	COG0756	dUTP diphosphatase activity
H4K32_RS18430	COG5434	Belongs to the glycosyl hydrolase 28 family
H4K32_RS18450	COG3397	chitin binding
H4K32_RS18470	COG0456	acetyltransferase
H4K32_RS18480	COG1064	alcohol dehydrogenase
H4K32_RS18495	COG3848	Pyruvate phosphate dikinase
H4K32_RS18495	COG0574	Belongs to the PEP-utilizing enzyme family
H4K32_RS18500	COG1070	Carbohydrate kinase
H4K32_RS18515	COG3507	Belongs to the glycosyl hydrolase 43 family
H4K32_RS18520	COG2211	Major facilitator Superfamily
H4K32_RS18530	COG0174	glutamine synthetase
H4K32_RS18535	COG0789	Transcriptional regulator
H4K32_RS18540	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H4K32_RS18545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H4K32_RS18550	COG0464	growth
H4K32_RS18555	COG0860	N-Acetylmuramoyl-L-alanine amidase
H4K32_RS18560	COG4112	unkown
H4K32_RS18565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H4K32_RS18570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H4K32_RS18610	COG2076	Multidrug Resistance protein
H4K32_RS18620	COG1764	response to oxidative stress
H4K32_RS18625	COG4195	phage-related replication protein
H4K32_RS18635	COG1404	Belongs to the peptidase S8 family
H4K32_RS18645	COG3619	membrane
H4K32_RS18650	COG3209	COG3209 Rhs family protein
H4K32_RS18655	COG2124	cytochrome p450
H4K32_RS18660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS18660	COG3321	synthase
H4K32_RS18660	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H4K32_RS18660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H4K32_RS18665	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS18665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS18665	COG4221	oxidoreductase activity
H4K32_RS18665	COG3321	synthase
H4K32_RS18670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS18670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS18670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS18670	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS18670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS18670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4K32_RS18670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS18670	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS18670	COG3321	synthase
H4K32_RS18670	COG3321	synthase
H4K32_RS18675	COG0300	oxidoreductase activity
H4K32_RS18675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS18675	COG3321	synthase
H4K32_RS18675	COG4221	oxidoreductase activity
H4K32_RS18680	COG0318	PFAM AMP-dependent synthetase and ligase
H4K32_RS18680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4K32_RS18680	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS18680	COG0300	oxidoreductase activity
H4K32_RS18680	COG3321	synthase
H4K32_RS18685	COG1024	Enoyl-CoA hydratase
H4K32_RS18690	COG1024	Enoyl-CoA hydratase
H4K32_RS18695	COG3425	synthase
H4K32_RS18700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H4K32_RS18745	COG4550	Control of competence regulator ComK, YlbF/YmcA
H4K32_RS18765	COG2359	stage V sporulation protein S
H4K32_RS18770	COG1692	metallophosphoesterase
H4K32_RS18780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H4K32_RS18795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H4K32_RS18800	COG1426	Protein conserved in bacteria
H4K32_RS18815	COG0300	oxidoreductase activity
H4K32_RS18820	COG0612	Peptidase, M16
H4K32_RS18825	COG0612	Peptidase, M16
H4K32_RS18830	COG1033	growth of symbiont in host cell
H4K32_RS18830	COG2409	Drug exporters of the RND superfamily
H4K32_RS18835	COG1846	Transcriptional regulator
H4K32_RS18840	COG2814	Major facilitator Superfamily
H4K32_RS18845	COG2188	Transcriptional regulator
H4K32_RS18850	COG4980	gas vesicle protein
H4K32_RS18850	COG1674	ftsk spoiiie
H4K32_RS18860	COG0740	serine-type endopeptidase activity
H4K32_RS18865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H4K32_RS18875	COG0527	aspartate kinase activity
H4K32_RS18880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H4K32_RS18885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H4K32_RS18890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H4K32_RS18895	COG1873	PFAM PRC-barrel domain
H4K32_RS18900	COG0612	Peptidase, M16
H4K32_RS18905	COG0726	polysaccharide deacetylase
H4K32_RS18920	COG0196	riboflavin kinase activity
H4K32_RS18935	COG1550	Protein conserved in bacteria
H4K32_RS18945	COG1358	cellular component organization or biogenesis
H4K32_RS18950	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H4K32_RS18955	COG0195	Participates in both transcription termination and antitermination
H4K32_RS18965	COG2176	DNA-directed DNA polymerase activity
H4K32_RS18975	COG0750	zinc metalloprotease
H4K32_RS18985	COG4589	Belongs to the CDS family
H4K32_RS18990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H4K32_RS19020	COG1191	sigma factor activity
H4K32_RS19030	COG1776	CheC inhibitor of MCP methylation
H4K32_RS19035	COG0835	chemotaxis
H4K32_RS19040	COG0643	Histidine kinase
H4K32_RS19040	COG2198	Histidine kinase
H4K32_RS19045	COG2201	protein-glutamate methylesterase activity
H4K32_RS19050	COG0455	bacterial-type flagellum organization
H4K32_RS19055	COG1419	protein localization to endoplasmic reticulum
H4K32_RS19060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H4K32_RS19065	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H4K32_RS19070	COG1684	flagellar biosynthetic protein fliR
H4K32_RS19075	COG1987	bacterial-type flagellum assembly
H4K32_RS19080	COG1338	Plays a role in the flagellum-specific transport system
H4K32_RS19085	COG3190	flagellar
H4K32_RS19090	COG2201	protein-glutamate methylesterase activity
H4K32_RS19095	COG1776	CheC inhibitor of MCP methylation
H4K32_RS19095	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H4K32_RS19100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H4K32_RS19105	COG1580	Controls the rotational direction of flagella during chemotaxis
H4K32_RS19110	COG1582	Flagellar protein (FlbD)
H4K32_RS19115	COG4786	Flagellar basal body rod
H4K32_RS19120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H4K32_RS19125	COG3144	bacterial-type flagellum assembly
H4K32_RS19130	COG3334	PFAM MgtE intracellular
H4K32_RS19135	COG2882	bacterial-type flagellum organization
H4K32_RS19140	COG1157	protein secretion by the type III secretion system
H4K32_RS19145	COG1317	bacterial-type flagellum organization
H4K32_RS19150	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H4K32_RS19155	COG1766	The M ring may be actively involved in energy transduction
H4K32_RS19160	COG1677	Flagellar hook-basal body complex protein FliE
H4K32_RS19165	COG1558	bacterial-type flagellum-dependent cell motility
H4K32_RS19170	COG1815	bacterial-type flagellum-dependent cell motility
H4K32_RS19190	COG4974	Belongs to the 'phage' integrase family
H4K32_RS19200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H4K32_RS19205	COG0758	DNA mediated transformation
H4K32_RS19210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H4K32_RS19220	COG2257	FlhB HrpN YscU SpaS Family
H4K32_RS19235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H4K32_RS19260	COG1837	Belongs to the UPF0109 family
H4K32_RS19270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H4K32_RS19285	COG0552	protein localization to endoplasmic reticulum
H4K32_RS19290	COG1196	nuclear chromosome segregation
H4K32_RS19305	COG1028	Short-chain dehydrogenase reductase Sdr
H4K32_RS19310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H4K32_RS19325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H4K32_RS19330	COG1760	l-serine dehydratase
H4K32_RS19335	COG1760	l-serine dehydratase
H4K32_RS19340	COG1461	Dihydroxyacetone kinase
H4K32_RS19345	COG1302	Protein conserved in bacteria
H4K32_RS19360	COG1564	THIamine pyrophosphokinase
H4K32_RS19365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H4K32_RS19375	COG0515	serine threonine protein kinase
H4K32_RS19375	COG2815	serine threonine protein kinase
H4K32_RS19380	COG0631	protein serine/threonine phosphatase activity
H4K32_RS19390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H4K32_RS19390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H4K32_RS19400	COG0242	peptide deformylase activity
H4K32_RS19405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA