locus-tag	class	description
A5891_RS00010	COG0592	DNA-directed DNA polymerase activity
A5891_RS00015	COG2501	S4 domain
A5891_RS00030	COG0187	DNA topoisomerase II activity
A5891_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A5891_RS00070	COG0516	GMP reductase activity
A5891_RS00070	COG0517	IMP dehydrogenase activity
A5891_RS00075	COG1686	Belongs to the peptidase S11 family
A5891_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
A5891_RS00105	COG1428	Deoxynucleoside kinase
A5891_RS00110	COG1428	Deoxynucleoside kinase
A5891_RS00115	COG3858	chitin binding
A5891_RS00115	COG1388	LysM domain
A5891_RS00120	COG1335	isochorismatase
A5891_RS00125	COG0590	tRNA wobble adenosine to inosine editing
A5891_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A5891_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A5891_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A5891_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
A5891_RS00195	COG3853	Toxic anion resistance protein (TelA)
A5891_RS00200	COG1982	Orn Lys Arg decarboxylase major
A5891_RS00210	COG3870	Protein conserved in bacteria
A5891_RS00215	COG1728	Protein conserved in bacteria
A5891_RS00220	COG0470	DNA polymerase III
A5891_RS00225	COG1774	PSP1 C-terminal conserved region
A5891_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A5891_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A5891_RS00250	COG2002	toxin-antitoxin pair type II binding
A5891_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A5891_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A5891_RS00260	COG0084	hydrolase, TatD family'
A5891_RS00265	COG3583	domain protein
A5891_RS00265	COG3584	3D domain protein
A5891_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A5891_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A5891_RS00285	COG4466	Protein conserved in bacteria
A5891_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A5891_RS00305	COG0251	oxidation-reduction process
A5891_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A5891_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A5891_RS00345	COG2002	toxin-antitoxin pair type II binding
A5891_RS00350	COG2244	polysaccharide biosynthetic process
A5891_RS00355	COG3956	TIGRFAM MazG family protein
A5891_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A5891_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A5891_RS00380	COG1098	S1 RNA binding domain
A5891_RS00395	COG2208	phosphoserine phosphatase activity
A5891_RS00400	COG2304	oxidoreductase activity
A5891_RS00405	COG0515	serine threonine protein kinase
A5891_RS00410	COG0037	tRNA processing
A5891_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A5891_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A5891_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A5891_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A5891_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A5891_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
A5891_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A5891_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A5891_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A5891_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A5891_RS00475	COG1396	sequence-specific DNA binding
A5891_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A5891_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A5891_RS00565	COG4463	regulation of RNA biosynthetic process
A5891_RS00570	COG3880	PFAM UvrB UvrC protein
A5891_RS00580	COG0542	response to heat
A5891_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A5891_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A5891_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
A5891_RS00615	COG1045	serine acetyltransferase
A5891_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A5891_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A5891_RS00635	COG3688	RNA-binding protein containing a PIN domain
A5891_RS00640	COG1595	DNA-templated transcription, initiation
A5891_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A5891_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
A5891_RS00680	COG2813	Specifically methylates the guanine in position
A5891_RS00695	COG1358	cellular component organization or biogenesis
A5891_RS00720	COG0596	Alpha beta hydrolase
A5891_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A5891_RS00825	COG0201	protein transport
A5891_RS00835	COG0024	Methionine aminopeptidase
A5891_RS00845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A5891_RS00870	COG1122	ATPase activity
A5891_RS00875	COG1122	ATPase activity
A5891_RS00880	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A5891_RS00900	COG2226	methyltransferase
A5891_RS00905	COG2318	DinB family
A5891_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
A5891_RS00920	COG0489	protein tyrosine kinase activity
A5891_RS00930	COG2194	sulfuric ester hydrolase activity
A5891_RS00935	COG0726	polysaccharide deacetylase
A5891_RS00995	COG0738	Major facilitator superfamily
A5891_RS01000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A5891_RS01010	COG1063	alcohol dehydrogenase
A5891_RS01015	COG0659	secondary active sulfate transmembrane transporter activity
A5891_RS01020	COG0385	Bile acid
A5891_RS01025	COG2819	hydrolase of the alpha beta superfamily
A5891_RS01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5891_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5891_RS01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A5891_RS01045	COG2207	Transcriptional regulator
A5891_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A5891_RS01050	COG3876	Protein conserved in bacteria
A5891_RS01055	COG1472	Belongs to the glycosyl hydrolase 3 family
A5891_RS01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A5891_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5891_RS01065	COG1263	PTS System
A5891_RS01075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A5891_RS01080	COG1683	Conserved Protein
A5891_RS01110	COG1595	DNA-templated transcription, initiation
A5891_RS01115	COG5662	AntiSigma factor
A5891_RS01120	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A5891_RS01125	COG4856	YbbR-like protein
A5891_RS01155	COG5002	protein histidine kinase activity
A5891_RS01160	COG1136	(ABC) transporter
A5891_RS01165	COG0577	efflux transmembrane transporter activity
A5891_RS01170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A5891_RS01180	COG1346	cytolysis
A5891_RS01185	COG1380	Effector of murein hydrolase LrgA
A5891_RS01190	COG1846	Transcriptional regulator
A5891_RS01195	COG1113	amino acid transport
A5891_RS01200	COG1011	Hydrolase
A5891_RS01205	COG4585	Histidine kinase
A5891_RS01210	COG2197	response regulator
A5891_RS01215	COG1131	(ABC) transporter
A5891_RS01255	COG0531	amino acid
A5891_RS01260	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
A5891_RS01275	COG0584	glycerophosphoryl diester phosphodiesterase
A5891_RS01280	COG2271	Major facilitator Superfamily
A5891_RS01290	COG2368	4-hydroxyphenylacetate
A5891_RS01300	COG3409	Peptidoglycan-binding domain 1 protein
A5891_RS01315	COG1397	ADP-ribosylglycohydrolase
A5891_RS01320	COG5444	nuclease activity
A5891_RS01330	COG0371	Dehydrogenase
A5891_RS01340	COG1183	phosphatidylcholine synthase activity
A5891_RS01345	COG0586	Pfam SNARE associated Golgi protein
A5891_RS01350	COG0688	phosphatidylethanolamine metabolic process
A5891_RS01365	COG1301	dicarboxylic acid transport
A5891_RS01370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A5891_RS01375	COG0833	amino acid
A5891_RS01380	COG2040	homocysteine
A5891_RS01385	COG1115	amino acid carrier protein
A5891_RS01390	COG2066	Belongs to the glutaminase family
A5891_RS01395	COG4191	Histidine kinase
A5891_RS01400	COG0784	Response regulator, receiver
A5891_RS01405	COG3173	Aminoglycoside phosphotransferase
A5891_RS01420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A5891_RS01425	COG0778	Nitroreductase
A5891_RS01430	COG0346	lactoylglutathione lyase activity
A5891_RS01435	COG2259	Doxx family
A5891_RS01440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5891_RS01455	COG3773	Cell wall hydrolase
A5891_RS01460	COG3540	Alkaline phosphatase
A5891_RS01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A5891_RS01470	COG0805	protein transport
A5891_RS01480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A5891_RS01485	COG0477	Major facilitator Superfamily
A5891_RS01490	COG1309	transcriptional regulator
A5891_RS01495	COG0252	asparaginase activity
A5891_RS01500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A5891_RS01505	COG3012	SEC-C Motif Domain Protein
A5891_RS01505	COG1405	negative regulation of cell septum assembly
A5891_RS01520	COG1595	DNA-templated transcription, initiation
A5891_RS01525	COG1595	DNA-templated transcription, initiation
A5891_RS01530	COG1876	peptidase activity
A5891_RS01535	COG0457	Tetratricopeptide repeat
A5891_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS01545	COG0366	Alpha amylase catalytic
A5891_RS01550	COG0803	Belongs to the bacterial solute-binding protein 9 family
A5891_RS01555	COG1121	(ABC) transporter
A5891_RS01560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A5891_RS01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A5891_RS01570	COG2310	stress, protein
A5891_RS01575	COG2310	stress, protein
A5891_RS01580	COG2310	stress, protein
A5891_RS01585	COG0861	Integral membrane protein TerC family
A5891_RS01595	COG3853	Toxic anion resistance protein (TelA)
A5891_RS01600	COG0477	Major facilitator Superfamily
A5891_RS01605	COG0517	IMP dehydrogenase activity
A5891_RS01605	COG4175	Glycine betaine
A5891_RS01610	COG4176	ABC-type proline glycine betaine transport system permease component
A5891_RS01615	COG2113	Glycine betaine
A5891_RS01620	COG1473	amidohydrolase
A5891_RS01625	COG1288	antiporter activity
A5891_RS01645	COG2814	Major facilitator Superfamily
A5891_RS01650	COG1846	Transcriptional regulator
A5891_RS01655	COG1280	lysine exporter protein (LysE YggA)
A5891_RS01660	COG3403	YqcI/YcgG family
A5891_RS01665	COG1113	amino acid transport
A5891_RS01670	COG3665	Urea carboxylase-associated protein
A5891_RS01685	COG1660	Displays ATPase and GTPase activities
A5891_RS01690	COG1082	Xylose isomerase domain protein TIM barrel
A5891_RS01695	COG2271	Major facilitator Superfamily
A5891_RS01700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A5891_RS01705	COG3458	cephalosporin-C deacetylase activity
A5891_RS01710	COG3541	Predicted nucleotidyltransferase
A5891_RS01715	COG0506	proline dehydrogenase activity
A5891_RS01720	COG1012	belongs to the aldehyde dehydrogenase family
A5891_RS01725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A5891_RS01730	COG2508	Transcriptional regulator
A5891_RS01740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A5891_RS01740	COG1587	Uroporphyrinogen-III synthase
A5891_RS01745	COG2146	nitrite reductase [NAD(P)H] activity
A5891_RS01750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A5891_RS01755	COG0243	molybdopterin cofactor binding
A5891_RS01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A5891_RS01765	COG2223	nitrite transmembrane transporter activity
A5891_RS01770	COG0523	cobalamin synthesis protein
A5891_RS01775	COG1063	alcohol dehydrogenase
A5891_RS01780	COG1714	RDD family
A5891_RS01790	COG2723	6-phospho-beta-galactosidase activity
A5891_RS01800	COG3209	COG3209 Rhs family protein
A5891_RS01805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A5891_RS01810	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A5891_RS01815	COG1733	regulation of RNA biosynthetic process
A5891_RS01825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS01840	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A5891_RS01855	COG2364	Membrane
A5891_RS01860	COG1126	abc transporter atp-binding protein
A5891_RS01865	COG0765	amino acid transport
A5891_RS01875	COG0583	DNA-binding transcription factor activity
A5891_RS01880	COG0163	prenyltransferase activity
A5891_RS01885	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A5891_RS01900	COG3104	oligopeptide transport
A5891_RS01905	COG5434	Belongs to the glycosyl hydrolase 28 family
A5891_RS01915	COG0697	spore germination
A5891_RS01925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A5891_RS01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A5891_RS01935	COG0456	acetyltransferase
A5891_RS01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5891_RS01945	COG0765	amino acid transport
A5891_RS01950	COG1126	abc transporter atp-binding protein
A5891_RS01955	COG1473	amidohydrolase
A5891_RS01960	COG2079	MmgE PrpD family protein
A5891_RS01965	COG1136	(ABC) transporter
A5891_RS01970	COG0577	efflux transmembrane transporter activity
A5891_RS01975	COG0745	RESPONSE REGULATOR receiver
A5891_RS01980	COG3850	Histidine kinase
A5891_RS01980	COG5002	protein histidine kinase activity
A5891_RS01985	COG0457	Tetratricopeptide repeat
A5891_RS02000	COG0527	aspartate kinase activity
A5891_RS02005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5891_RS02010	COG4605	iron ion homeostasis
A5891_RS02015	COG4604	ABC transporter, ATP-binding protein
A5891_RS02020	COG4607	ABC-type enterochelin transport system periplasmic component
A5891_RS02025	COG2814	Major facilitator Superfamily
A5891_RS02030	COG1309	transcriptional regulator
A5891_RS02035	COG0778	Nitroreductase
A5891_RS02040	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A5891_RS02045	COG0640	Transcriptional regulator
A5891_RS02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A5891_RS02055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A5891_RS02060	COG1012	belongs to the aldehyde dehydrogenase family
A5891_RS02065	COG4975	Glucose uptake
A5891_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS02075	COG4549	nuclear export factor GLE1
A5891_RS02080	COG2372	response to copper ion
A5891_RS02080	COG1276	copper resistance
A5891_RS02085	COG1349	DNA-binding transcription factor activity
A5891_RS02095	COG2213	PTS system mannitol-specific
A5891_RS02100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5891_RS02110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A5891_RS02115	COG0561	phosphatase activity
A5891_RS02125	COG1914	H( )-stimulated, divalent metal cation uptake system
A5891_RS02135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A5891_RS02140	COG1984	allophanate hydrolase subunit 2
A5891_RS02145	COG1414	Transcriptional regulator
A5891_RS02150	COG2755	lipolytic protein G-D-S-L family
A5891_RS02160	COG2329	Antibiotic biosynthesis monooxygenase
A5891_RS02165	COG0768	penicillin binding
A5891_RS02170	COG4989	oxidoreductase activity
A5891_RS02175	COG3711	transcriptional antiterminator
A5891_RS02180	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS02190	COG1917	Cupin 2, conserved barrel domain protein
A5891_RS02195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A5891_RS02200	COG3871	stress protein (general stress protein 26)
A5891_RS02210	COG2814	Major facilitator Superfamily
A5891_RS02215	COG1522	sequence-specific DNA binding
A5891_RS02220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A5891_RS02220	COG0551	DNA topoisomerase type I activity
A5891_RS02225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A5891_RS02230	COG3706	GGDEF domain
A5891_RS02235	COG5298	Protein conserved in bacteria
A5891_RS02240	COG1215	transferase activity, transferring glycosyl groups
A5891_RS02250	COG0531	amino acid
A5891_RS02260	COG0028	Belongs to the TPP enzyme family
A5891_RS02265	COG5632	N-Acetylmuramoyl-L-alanine amidase
A5891_RS02265	COG1388	LysM domain
A5891_RS02265	COG3409	Peptidoglycan-binding domain 1 protein
A5891_RS02285	COG0457	Tetratricopeptide repeat
A5891_RS02315	COG1914	H( )-stimulated, divalent metal cation uptake system
A5891_RS02330	COG4876	unkown
A5891_RS02340	COG2076	Multidrug Resistance protein
A5891_RS02345	COG2217	Heavy metal translocating P-type atpase
A5891_RS02350	COG3729	General stress protein
A5891_RS02355	COG0662	Cupin 2, conserved barrel domain protein
A5891_RS02360	COG2329	Antibiotic biosynthesis monooxygenase
A5891_RS02365	COG3546	catalase activity
A5891_RS02370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A5891_RS02375	COG3290	protein histidine kinase activity
A5891_RS02380	COG4565	transcriptional regulatory protein
A5891_RS02385	COG1301	dicarboxylic acid transport
A5891_RS02390	COG0628	permease
A5891_RS02395	COG1131	(ABC) transporter
A5891_RS02400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A5891_RS02410	COG1960	acyl-CoA dehydrogenase activity
A5891_RS02425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A5891_RS02430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5891_RS02440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A5891_RS02445	COG0513	Belongs to the DEAD box helicase family
A5891_RS02450	COG3402	PFAM membrane-flanked domain
A5891_RS02455	COG3428	Bacterial PH domain
A5891_RS02460	COG0705	Rhomboid family
A5891_RS02470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A5891_RS02475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A5891_RS02480	COG0864	Transcriptional regulator
A5891_RS02485	COG2337	Toxic component of a toxin-antitoxin (TA) module
A5891_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
A5891_RS02495	COG1366	Belongs to the anti-sigma-factor antagonist family
A5891_RS02500	COG2172	sigma factor antagonist activity
A5891_RS02505	COG2208	phosphoserine phosphatase activity
A5891_RS02510	COG1366	Belongs to the anti-sigma-factor antagonist family
A5891_RS02520	COG1191	sigma factor activity
A5891_RS02525	COG2208	phosphoserine phosphatase activity
A5891_RS02530	COG2183	response to ionizing radiation
A5891_RS02595	COG5444	nuclease activity
A5891_RS02600	COG0457	Tetratricopeptide repeat
A5891_RS02605	COG0477	Major facilitator Superfamily
A5891_RS02620	COG2030	dehydratase
A5891_RS02630	COG1959	2 iron, 2 sulfur cluster binding
A5891_RS02635	COG2910	NAD(P)H-binding
A5891_RS02645	COG1278	Cold shock
A5891_RS02650	COG1329	Transcriptional regulator
A5891_RS02655	COG1937	Protein conserved in bacteria
A5891_RS02660	COG2210	Belongs to the sulfur carrier protein TusA family
A5891_RS02665	COG1054	Belongs to the UPF0176 family
A5891_RS02670	COG0425	Belongs to the sulfur carrier protein TusA family
A5891_RS02670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A5891_RS02675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A5891_RS02675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A5891_RS02680	COG0425	Belongs to the sulfur carrier protein TusA family
A5891_RS02685	COG0730	response to heat
A5891_RS02690	COG1794	racemase activity, acting on amino acids and derivatives
A5891_RS02705	COG3621	Patatin-like phospholipase
A5891_RS02715	COG0662	Cupin 2, conserved barrel domain protein
A5891_RS02730	COG0277	FAD linked oxidase domain protein
A5891_RS02750	COG0662	Cupin 2, conserved barrel domain protein
A5891_RS02755	COG2318	DinB family
A5891_RS02790	COG1064	alcohol dehydrogenase
A5891_RS02795	COG0789	Transcriptional regulator
A5891_RS02805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A5891_RS02820	COG2814	Major facilitator Superfamily
A5891_RS02825	COG1309	transcriptional regulator
A5891_RS02830	COG0697	spore germination
A5891_RS02835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A5891_RS02840	COG5577	PFAM Coat F domain
A5891_RS02850	COG1063	alcohol dehydrogenase
A5891_RS02855	COG5577	PFAM Coat F domain
A5891_RS02865	COG4585	Histidine kinase
A5891_RS02870	COG2197	response regulator
A5891_RS02875	COG2409	Drug exporters of the RND superfamily
A5891_RS02880	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A5891_RS02885	COG0488	(ABC) transporter
A5891_RS02890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A5891_RS02895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A5891_RS02905	COG2814	Major facilitator Superfamily
A5891_RS02910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A5891_RS02920	COG0730	response to heat
A5891_RS02925	COG0456	acetyltransferase
A5891_RS02930	COG0789	Transcriptional regulator
A5891_RS02930	COG4978	Transcriptional regulator
A5891_RS02935	COG0697	spore germination
A5891_RS02940	COG1051	belongs to the nudix hydrolase family
A5891_RS02945	COG2226	methyltransferase
A5891_RS02950	COG0473	3-isopropylmalate dehydrogenase activity
A5891_RS02955	COG1802	Transcriptional regulator
A5891_RS02960	COG1819	glycosyl
A5891_RS02975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A5891_RS02980	COG1388	LysM domain
A5891_RS02985	COG2814	Major facilitator Superfamily
A5891_RS02990	COG2188	Transcriptional regulator
A5891_RS02995	COG2186	Transcriptional regulator
A5891_RS03000	COG2807	transmembrane transport
A5891_RS03005	COG2076	Multidrug Resistance protein
A5891_RS03010	COG2076	Multidrug Resistance protein
A5891_RS03015	COG1309	transcriptional regulator
A5891_RS03020	COG0531	amino acid
A5891_RS03030	COG3832	glyoxalase III activity
A5891_RS03035	COG0604	alcohol dehydrogenase
A5891_RS03040	COG2814	Major facilitator Superfamily
A5891_RS03080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A5891_RS03085	COG0802	atpase or kinase
A5891_RS03090	COG1214	PFAM Peptidase M22, glycoprotease
A5891_RS03095	COG0456	acetyltransferase
A5891_RS03100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A5891_RS03105	COG0488	(ABC) transporter
A5891_RS03120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A5891_RS03125	COG0805	protein transport
A5891_RS03135	COG1266	CAAX protease self-immunity
A5891_RS03170	COG0457	Tetratricopeptide repeat
A5891_RS03175	COG1063	alcohol dehydrogenase
A5891_RS03180	COG2211	Major facilitator Superfamily
A5891_RS03185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5891_RS03195	COG1842	Phage shock protein A
A5891_RS03200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A5891_RS03205	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A5891_RS03210	COG4260	virion core protein, lumpy skin disease virus
A5891_RS03215	COG2755	lipolytic protein G-D-S-L family
A5891_RS03215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A5891_RS03225	COG1595	DNA-templated transcription, initiation
A5891_RS03230	COG1063	alcohol dehydrogenase
A5891_RS03235	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A5891_RS03240	COG0823	Involved in the tonB-independent uptake of proteins
A5891_RS03250	COG2132	Multicopper oxidase
A5891_RS03255	COG1113	amino acid transport
A5891_RS03260	COG0714	Associated with various cellular activities
A5891_RS03265	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A5891_RS03270	COG1305	Transglutaminase-like
A5891_RS03295	COG2252	PERMEase
A5891_RS03300	COG3064	Membrane
A5891_RS03315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A5891_RS03320	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A5891_RS03325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A5891_RS03330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A5891_RS03335	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A5891_RS03350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A5891_RS03360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A5891_RS03365	COG0138	bifunctional purine biosynthesis protein purh
A5891_RS03370	COG0151	Belongs to the GarS family
A5891_RS03380	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A5891_RS03385	COG1470	cell adhesion involved in biofilm formation
A5891_RS03390	COG4496	protein, YerC YecD
A5891_RS03395	COG0069	glutamate synthase activity
A5891_RS03410	COG0210	DNA helicase
A5891_RS03420	COG4851	CamS sex pheromone cAM373 precursor
A5891_RS03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A5891_RS03430	COG1285	pathogenesis
A5891_RS03435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A5891_RS03455	COG1309	transcriptional regulator
A5891_RS03460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A5891_RS03465	COG1597	lipid kinase activity
A5891_RS03470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A5891_RS03480	COG1131	(ABC) transporter
A5891_RS03520	COG5444	nuclease activity
A5891_RS03550	COG3546	catalase activity
A5891_RS03555	COG0454	-acetyltransferase
A5891_RS03565	COG2323	membrane
A5891_RS03570	COG2329	Antibiotic biosynthesis monooxygenase
A5891_RS03575	COG0346	lactoylglutathione lyase activity
A5891_RS03580	COG1366	Belongs to the anti-sigma-factor antagonist family
A5891_RS03585	COG5583	Uncharacterized small protein (DUF2292)
A5891_RS03590	COG0196	riboflavin kinase activity
A5891_RS03595	COG0670	Belongs to the BI1 family
A5891_RS03600	COG1846	Transcriptional regulator
A5891_RS03605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A5891_RS03615	COG2124	cytochrome p450
A5891_RS03615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A5891_RS03620	COG1368	sulfuric ester hydrolase activity
A5891_RS03625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A5891_RS03630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5891_RS03635	COG1442	glycosyl transferase family 8
A5891_RS03640	COG1216	Glycosyl transferase, family 2
A5891_RS03645	COG1442	glycosyl transferase family 8
A5891_RS03650	COG2223	nitrite transmembrane transporter activity
A5891_RS03655	COG0531	amino acid
A5891_RS03660	COG1012	belongs to the aldehyde dehydrogenase family
A5891_RS03665	COG0840	transmembrane signaling receptor activity
A5891_RS03670	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS03675	COG0457	Tetratricopeptide repeat
A5891_RS03675	COG0463	Glycosyl transferase, family 2
A5891_RS03680	COG0488	(ABC) transporter
A5891_RS03685	COG0789	Transcriptional regulator
A5891_RS03690	COG2814	Major facilitator Superfamily
A5891_RS03695	COG0488	(ABC) transporter
A5891_RS03700	COG0513	Belongs to the DEAD box helicase family
A5891_RS03705	COG0456	acetyltransferase
A5891_RS03710	COG2130	NADP-dependent
A5891_RS03725	COG3866	Pectate lyase
A5891_RS03730	COG0471	metal ion transport
A5891_RS03750	COG3290	protein histidine kinase activity
A5891_RS03755	COG4565	transcriptional regulatory protein
A5891_RS03760	COG3181	Tripartite tricarboxylate transporter family receptor
A5891_RS03765	COG2851	Citrate transporter
A5891_RS03770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A5891_RS03775	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A5891_RS03785	COG2258	MOSC domain
A5891_RS03800	COG0024	Methionine aminopeptidase
A5891_RS03805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5891_RS03805	COG1263	PTS System
A5891_RS03815	COG1368	sulfuric ester hydrolase activity
A5891_RS03825	COG0071	Belongs to the small heat shock protein (HSP20) family
A5891_RS03840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5891_RS03840	COG1263	PTS System
A5891_RS03845	COG0366	Alpha amylase catalytic
A5891_RS03850	COG2188	Transcriptional regulator
A5891_RS03855	COG0778	Nitroreductase
A5891_RS03870	COG0737	Belongs to the 5'-nucleotidase family
A5891_RS03875	COG0693	protein deglycase activity
A5891_RS03880	COG1609	Transcriptional regulator
A5891_RS03895	COG2814	Major facilitator Superfamily
A5891_RS03905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A5891_RS03910	COG4980	gas vesicle protein
A5891_RS03915	COG1295	ribonuclease BN
A5891_RS03920	COG0477	Major facilitator Superfamily
A5891_RS03925	COG0387	Pfam Sodium calcium exchanger
A5891_RS03935	COG0668	transmembrane transport
A5891_RS03940	COG0535	radical SAM domain protein
A5891_RS03950	COG0726	polysaccharide deacetylase
A5891_RS03970	COG0745	RESPONSE REGULATOR receiver
A5891_RS03975	COG2205	protein histidine kinase activity
A5891_RS03980	COG2084	Dehydrogenase
A5891_RS03990	COG0598	Magnesium transport protein CorA
A5891_RS03995	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A5891_RS04000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A5891_RS04010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A5891_RS04015	COG4637	Psort location Cytoplasmic, score
A5891_RS04020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A5891_RS04025	COG0022	dehydrogenase e1 component
A5891_RS04030	COG0508	dehydrogenase complex catalyzes the overall conversion of
A5891_RS04035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A5891_RS04040	COG3284	Transcriptional regulator
A5891_RS04050	COG1486	melibiose metabolic process
A5891_RS04055	COG1737	Transcriptional regulator
A5891_RS04060	COG1263	PTS System
A5891_RS04060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5891_RS04070	COG1132	(ABC) transporter
A5891_RS04075	COG1132	(ABC) transporter
A5891_RS04080	COG2259	Doxx family
A5891_RS04085	COG2514	catechol 2,3-dioxygenase activity
A5891_RS04095	COG1695	Transcriptional regulator
A5891_RS04100	COG2249	NAD(P)H dehydrogenase (quinone) activity
A5891_RS04105	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
A5891_RS04110	COG0574	Belongs to the PEP-utilizing enzyme family
A5891_RS04110	COG3848	Pyruvate phosphate dikinase
A5891_RS04115	COG2732	(Barnase) inhibitor
A5891_RS04120	COG2318	DinB family
A5891_RS04125	COG2814	Major facilitator Superfamily
A5891_RS04130	COG1846	Transcriptional regulator
A5891_RS04135	COG0392	lysyltransferase activity
A5891_RS04135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A5891_RS04140	COG0384	phenazine biosynthesis protein PhzF
A5891_RS04145	COG0778	Nitroreductase
A5891_RS04160	COG1090	epimerase
A5891_RS04175	COG2814	Major facilitator Superfamily
A5891_RS04185	COG3591	Belongs to the peptidase S1B family
A5891_RS04200	COG3103	Sh3 type 3 domain protein
A5891_RS04205	COG5658	integral membrane protein
A5891_RS04210	COG0596	Alpha beta hydrolase
A5891_RS04215	COG0463	Glycosyl transferase, family 2
A5891_RS04220	COG4485	Bacterial membrane protein, YfhO
A5891_RS04225	COG1988	membrane-bound metal-dependent
A5891_RS04230	COG1194	a g-specific adenine glycosylase
A5891_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS04260	COG1132	(ABC) transporter
A5891_RS04265	COG4129	membrane
A5891_RS04275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A5891_RS04280	COG0735	belongs to the Fur family
A5891_RS04395	COG3340	Belongs to the peptidase S51 family
A5891_RS04405	COG0277	FAD linked oxidase domain protein
A5891_RS04415	COG0747	negative chemotaxis
A5891_RS04420	COG0601	transmembrane transport
A5891_RS04425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A5891_RS04430	COG0444	Belongs to the ABC transporter superfamily
A5891_RS04435	COG4608	Belongs to the ABC transporter superfamily
A5891_RS04440	COG0753	catalase activity
A5891_RS04450	COG1116	anion transmembrane transporter activity
A5891_RS04455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A5891_RS04460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A5891_RS04480	COG1476	TRANSCRIPTIONal
A5891_RS04490	COG3382	B3 4 domain protein
A5891_RS04495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A5891_RS04505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A5891_RS04510	COG0789	Transcriptional regulator
A5891_RS04515	COG1664	Polymer-forming cytoskeletal
A5891_RS04520	COG1664	Polymer-forming cytoskeletal
A5891_RS04525	COG2766	serine protein kinase
A5891_RS04535	COG1846	Transcriptional regulator
A5891_RS04540	COG1566	PFAM secretion protein HlyD family protein
A5891_RS04545	COG2814	Major facilitator Superfamily
A5891_RS04550	COG0655	NAD(P)H dehydrogenase (quinone) activity
A5891_RS04560	COG1131	(ABC) transporter
A5891_RS04565	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A5891_RS04570	COG1278	Cold shock
A5891_RS04575	COG1464	Belongs to the NlpA lipoprotein family
A5891_RS04580	COG3706	GGDEF domain
A5891_RS04585	COG1823	symporter activity
A5891_RS04605	COG5577	PFAM Coat F domain
A5891_RS04610	COG1525	nuclease
A5891_RS04610	COG0737	Belongs to the 5'-nucleotidase family
A5891_RS04610	COG4085	toxin activity
A5891_RS04615	COG3764	Sortase (surface protein transpeptidase)
A5891_RS04620	COG0564	pseudouridine synthase activity
A5891_RS04630	COG0517	IMP dehydrogenase activity
A5891_RS04635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A5891_RS04640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A5891_RS04640	COG3153	acetyltransferase
A5891_RS04645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A5891_RS04650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A5891_RS04655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A5891_RS04665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A5891_RS04670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A5891_RS04675	COG4585	Histidine kinase
A5891_RS04675	COG2203	Gaf domain
A5891_RS04680	COG2197	response regulator
A5891_RS04685	COG0431	NADPH-dependent FMN reductase
A5891_RS04700	COG0791	NLP P60 protein
A5891_RS04700	COG1388	LysM domain
A5891_RS04705	COG1959	2 iron, 2 sulfur cluster binding
A5891_RS04710	COG0668	transmembrane transport
A5891_RS04715	COG2719	SpoVR family
A5891_RS04720	COG1785	Belongs to the alkaline phosphatase family
A5891_RS04725	COG0791	NLP P60 protein
A5891_RS04725	COG1388	LysM domain
A5891_RS04730	COG0583	DNA-binding transcription factor activity
A5891_RS04735	COG0372	Belongs to the citrate synthase family
A5891_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS04745	COG0531	amino acid
A5891_RS04750	COG0733	neurotransmitter:sodium symporter activity
A5891_RS04765	COG1595	DNA-templated transcription, initiation
A5891_RS04770	COG0204	Acyl-transferase
A5891_RS04775	COG1253	flavin adenine dinucleotide binding
A5891_RS04780	COG0789	Transcriptional regulator
A5891_RS04785	COG0436	Aminotransferase
A5891_RS04790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A5891_RS04795	COG1253	flavin adenine dinucleotide binding
A5891_RS04800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A5891_RS04805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A5891_RS04810	COG0584	glycerophosphoryl diester phosphodiesterase
A5891_RS04815	COG0668	transmembrane transport
A5891_RS04820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A5891_RS04825	COG0726	polysaccharide deacetylase
A5891_RS04830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A5891_RS04835	COG3226	Transcriptional regulator
A5891_RS04845	COG0589	response to stress
A5891_RS04850	COG1132	(ABC) transporter
A5891_RS04855	COG1132	(ABC) transporter
A5891_RS04860	COG0702	epimerase
A5891_RS04875	COG0189	ligase activity
A5891_RS04880	COG0189	ligase activity
A5891_RS04895	COG4335	DNA alkylation repair
A5891_RS04900	COG0561	phosphatase activity
A5891_RS04905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A5891_RS04915	COG0475	glutathione-regulated potassium exporter activity
A5891_RS04920	COG0490	domain, Protein
A5891_RS04930	COG1024	Enoyl-CoA hydratase
A5891_RS04940	COG4152	abc transporter atp-binding protein
A5891_RS04945	COG1668	transmembrane transport
A5891_RS04950	COG0420	3'-5' exonuclease activity
A5891_RS04955	COG4717	serine-type aminopeptidase activity
A5891_RS04970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A5891_RS05000	COG4980	gas vesicle protein
A5891_RS05015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A5891_RS05020	COG0537	adenosine 5'-monophosphoramidase activity
A5891_RS05025	COG1131	(ABC) transporter
A5891_RS05030	COG4473	ABC transporter
A5891_RS05040	COG1473	amidohydrolase
A5891_RS05045	COG3069	C4-dicarboxylate transmembrane transporter activity
A5891_RS05050	COG2329	Antibiotic biosynthesis monooxygenase
A5891_RS05055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A5891_RS05065	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A5891_RS05070	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A5891_RS05075	COG1309	transcriptional regulator
A5891_RS05080	COG1511	domain protein
A5891_RS05085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A5891_RS05095	COG1363	Peptidase, m42
A5891_RS05100	COG1301	dicarboxylic acid transport
A5891_RS05110	COG1234	tRNA 3'-trailer cleavage
A5891_RS05115	COG0095	Lipoate-protein ligase
A5891_RS05120	COG0702	epimerase
A5891_RS05125	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS05135	COG0501	Belongs to the peptidase M48B family
A5891_RS05140	COG1404	Belongs to the peptidase S8 family
A5891_RS05150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A5891_RS05155	COG0406	alpha-ribazole phosphatase activity
A5891_RS05160	COG0183	Belongs to the thiolase family
A5891_RS05165	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS05170	COG1268	BioY protein
A5891_RS05175	COG0840	transmembrane signaling receptor activity
A5891_RS05180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A5891_RS05180	COG0723	plastoquinol--plastocyanin reductase activity
A5891_RS05185	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS05195	COG4903	ComK protein
A5891_RS05205	COG5646	InterPro IPR014922
A5891_RS05225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A5891_RS05240	COG0398	Pfam SNARE associated Golgi protein
A5891_RS05245	COG0681	Belongs to the peptidase S26 family
A5891_RS05250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A5891_RS05255	COG1846	Transcriptional regulator
A5891_RS05260	COG3180	Ammonia monooxygenase
A5891_RS05265	COG2814	Major facilitator Superfamily
A5891_RS05275	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A5891_RS05280	COG2323	membrane
A5891_RS05295	COG0420	3'-5' exonuclease activity
A5891_RS05300	COG0419	ATPase involved in DNA repair
A5891_RS05305	COG1403	HNH endonuclease
A5891_RS05345	COG0179	Fumarylacetoacetate (FAA) hydrolase
A5891_RS05360	COG0367	asparagine synthase
A5891_RS05365	COG1562	ergosterol biosynthetic process
A5891_RS05370	COG0534	Mate efflux family protein
A5891_RS05375	COG2207	Transcriptional regulator
A5891_RS05375	COG1917	Cupin 2, conserved barrel domain protein
A5891_RS05380	COG0673	inositol 2-dehydrogenase activity
A5891_RS05385	COG2318	DinB family
A5891_RS05390	COG1279	arginine transmembrane transporter activity
A5891_RS05395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A5891_RS05400	COG1357	PFAM Pentapeptide repeats (8 copies)
A5891_RS05405	COG2153	protein acetylation
A5891_RS05410	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A5891_RS05410	COG0646	methionine synthase
A5891_RS05420	COG2996	Protein conserved in bacteria
A5891_RS05425	COG1744	ABC transporter substrate-binding protein PnrA-like
A5891_RS05430	COG0840	transmembrane signaling receptor activity
A5891_RS05435	COG2124	cytochrome p450
A5891_RS05440	COG1307	EDD domain protein, DegV family
A5891_RS05445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A5891_RS05460	COG0561	phosphatase activity
A5891_RS05465	COG1073	alpha beta
A5891_RS05470	COG2151	metal-sulfur cluster biosynthetic enzyme
A5891_RS05480	COG0277	FAD linked oxidase domain protein
A5891_RS05485	COG2271	Major facilitator Superfamily
A5891_RS05495	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A5891_RS05505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A5891_RS05510	COG0505	Belongs to the CarA family
A5891_RS05515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A5891_RS05520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A5891_RS05535	COG2267	carboxylic ester hydrolase activity
A5891_RS05545	COG1744	ABC transporter substrate-binding protein PnrA-like
A5891_RS05560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A5891_RS05565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A5891_RS05570	COG5504	Zn-dependent protease
A5891_RS05575	COG0444	Belongs to the ABC transporter superfamily
A5891_RS05580	COG4608	Belongs to the ABC transporter superfamily
A5891_RS05590	COG0601	transmembrane transport
A5891_RS05595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A5891_RS05605	COG0180	Tryptophanyl-tRNA synthetase
A5891_RS05610	COG4166	transmembrane transport
A5891_RS05615	COG0601	transmembrane transport
A5891_RS05620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A5891_RS05625	COG0444	Belongs to the ABC transporter superfamily
A5891_RS05630	COG4608	Belongs to the ABC transporter superfamily
A5891_RS05640	COG0456	acetyltransferase
A5891_RS05645	COG1393	Belongs to the ArsC family
A5891_RS05650	COG0861	Integral membrane protein TerC family
A5891_RS05655	COG4862	establishment of competence for transformation
A5891_RS05660	COG4469	Competence protein
A5891_RS05665	COG1164	Oligoendopeptidase f
A5891_RS05670	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A5891_RS05675	COG2346	COG2346, Truncated hemoglobins
A5891_RS05680	COG0741	lytic transglycosylase activity
A5891_RS05685	COG4116	CYTH
A5891_RS05695	COG2357	RelA SpoT domain protein
A5891_RS05700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A5891_RS05705	COG0564	pseudouridine synthase activity
A5891_RS05715	COG0475	glutathione-regulated potassium exporter activity
A5891_RS05715	COG0569	domain protein
A5891_RS05720	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A5891_RS05725	COG0352	thiamine-phosphate diphosphorylase activity
A5891_RS05730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A5891_RS05735	COG2104	thiamine diphosphate biosynthetic process
A5891_RS05745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A5891_RS05750	COG0351	phosphomethylpyrimidine kinase
A5891_RS05755	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A5891_RS05810	COG0210	DNA helicase
A5891_RS05830	COG1131	(ABC) transporter
A5891_RS05840	COG2153	protein acetylation
A5891_RS05850	COG2382	esterase
A5891_RS05855	COG0626	cystathionine gamma-synthase activity
A5891_RS05860	COG0626	cystathionine gamma-synthase activity
A5891_RS05890	COG5444	nuclease activity
A5891_RS05900	COG0346	lactoylglutathione lyase activity
A5891_RS05905	COG2367	Beta-lactamase
A5891_RS05910	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A5891_RS05915	COG0477	Major facilitator Superfamily
A5891_RS05920	COG1846	Transcriptional regulator
A5891_RS05930	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A5891_RS05935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A5891_RS05940	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A5891_RS05945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A5891_RS05945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A5891_RS05950	COG1447	Phosphotransferase system cellobiose-specific component IIA
A5891_RS05960	COG1349	DNA-binding transcription factor activity
A5891_RS05980	COG1285	pathogenesis
A5891_RS05990	COG2205	protein histidine kinase activity
A5891_RS06000	COG3383	formate dehydrogenase (NAD+) activity
A5891_RS06005	COG2427	Protein of unknown function (DUF1641)
A5891_RS06010	COG2124	cytochrome p450
A5891_RS06015	COG1819	glycosyl
A5891_RS06025	COG1587	Uroporphyrinogen-III synthase
A5891_RS06030	COG0390	transport system, permease component
A5891_RS06035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A5891_RS06040	COG0697	spore germination
A5891_RS06045	COG4297	protein containing double-stranded beta helix domain
A5891_RS06055	COG1252	NADH dehydrogenase
A5891_RS06065	COG2211	Major facilitator Superfamily
A5891_RS06070	COG1609	Transcriptional regulator
A5891_RS06075	COG0246	Mannitol dehydrogenase
A5891_RS06080	COG2721	sulfolactate sulfo-lyase activity
A5891_RS06085	COG0745	RESPONSE REGULATOR receiver
A5891_RS06090	COG2770	Histidine kinase
A5891_RS06090	COG2205	protein histidine kinase activity
A5891_RS06110	COG4585	Histidine kinase
A5891_RS06115	COG2197	response regulator
A5891_RS06140	COG0730	response to heat
A5891_RS06145	COG2318	DinB family
A5891_RS06150	COG0457	Tetratricopeptide repeat
A5891_RS06155	COG5632	N-Acetylmuramoyl-L-alanine amidase
A5891_RS06155	COG3409	Peptidoglycan-binding domain 1 protein
A5891_RS06155	COG1388	LysM domain
A5891_RS06165	COG4195	phage-related replication protein
A5891_RS06170	COG2856	Zn peptidase
A5891_RS06175	COG1396	sequence-specific DNA binding
A5891_RS06185	COG1522	sequence-specific DNA binding
A5891_RS06190	COG1484	DNA-dependent DNA replication
A5891_RS06205	COG1595	DNA-templated transcription, initiation
A5891_RS06210	COG3728	DNA packaging
A5891_RS06210	COG5484	DNA packaging
A5891_RS06215	COG1783	phage Terminase large subunit
A5891_RS06220	COG5518	Phage portal protein
A5891_RS06225	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A5891_RS06230	COG4653	Phage capsid family
A5891_RS06275	COG3953	SLT domain
A5891_RS06275	COG3953	SLT domain
A5891_RS06275	COG5412	phage tail tape measure protein
A5891_RS06275	COG5412	phage tail tape measure protein
A5891_RS06275	COG3953	SLT domain
A5891_RS06275	COG5412	phage tail tape measure protein
A5891_RS06280	COG1652	LysM domain
A5891_RS06285	COG4193	domain, Protein
A5891_RS06295	COG3628	GPW Gp25 family protein
A5891_RS06300	COG3299	homolog of phage Mu protein gp47
A5891_RS06305	COG3778	Protein conserved in bacteria
A5891_RS06345	COG3409	Peptidoglycan-binding domain 1 protein
A5891_RS06345	COG5632	N-Acetylmuramoyl-L-alanine amidase
A5891_RS06360	COG0306	phosphate transporter
A5891_RS06365	COG1392	Phosphate transport regulator
A5891_RS06370	COG0531	amino acid
A5891_RS06375	COG0346	lactoylglutathione lyase activity
A5891_RS06380	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A5891_RS06385	COG0463	Glycosyl transferase, family 2
A5891_RS06390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A5891_RS06395	COG0477	Major facilitator Superfamily
A5891_RS06400	COG2362	D-Aminopeptidase
A5891_RS06405	COG0601	transmembrane transport
A5891_RS06410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A5891_RS06415	COG0444	Belongs to the ABC transporter superfamily
A5891_RS06420	COG4166	transmembrane transport
A5891_RS06425	COG1619	proteins homologs of microcin C7 resistance protein MccF
A5891_RS06430	COG4948	Mandelate Racemase Muconate Lactonizing
A5891_RS06435	COG0791	NLP P60 protein
A5891_RS06440	COG4608	Belongs to the ABC transporter superfamily
A5891_RS06445	COG2706	6-phosphogluconolactonase activity
A5891_RS06450	COG1834	amidinotransferase
A5891_RS06455	COG1607	acyl-coa hydrolase
A5891_RS06460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A5891_RS06465	COG2076	Multidrug Resistance protein
A5891_RS06470	COG2076	Multidrug Resistance protein
A5891_RS06475	COG0788	formyltetrahydrofolate deformylase activity
A5891_RS06480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A5891_RS06490	COG1764	response to oxidative stress
A5891_RS06495	COG1846	Transcriptional regulator
A5891_RS06500	COG1764	response to oxidative stress
A5891_RS06515	COG0463	Glycosyl transferase, family 2
A5891_RS06515	COG0457	Tetratricopeptide repeat
A5891_RS06535	COG1404	Belongs to the peptidase S8 family
A5891_RS06540	COG1366	Belongs to the anti-sigma-factor antagonist family
A5891_RS06545	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A5891_RS06550	COG1122	ATPase activity
A5891_RS06555	COG4721	ABC-type cobalt transport system, permease component
A5891_RS06560	COG3858	chitin binding
A5891_RS06560	COG1388	LysM domain
A5891_RS06565	COG2239	Acts as a magnesium transporter
A5891_RS06570	COG0789	Transcriptional regulator
A5891_RS06580	COG1846	Transcriptional regulator
A5891_RS06585	COG0726	polysaccharide deacetylase
A5891_RS06590	COG1793	dna ligase
A5891_RS06590	COG3285	dna ligase
A5891_RS06595	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A5891_RS06605	COG0586	Pfam SNARE associated Golgi protein
A5891_RS06610	COG0861	Integral membrane protein TerC family
A5891_RS06615	COG1191	sigma factor activity
A5891_RS06640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A5891_RS06645	COG2323	membrane
A5891_RS06650	COG3594	Acyltransferase
A5891_RS06655	COG5002	protein histidine kinase activity
A5891_RS06660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A5891_RS06675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A5891_RS06680	COG0436	Aminotransferase
A5891_RS06710	COG3852	Histidine kinase
A5891_RS06715	COG1846	Transcriptional regulator
A5891_RS06720	COG1360	Flagellar Motor Protein
A5891_RS06725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A5891_RS06730	COG0542	response to heat
A5891_RS06735	COG3949	Membrane
A5891_RS06750	COG0720	synthase
A5891_RS06755	COG0602	queuosine metabolic process
A5891_RS06770	COG1733	regulation of RNA biosynthetic process
A5891_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS06790	COG4873	Protein conserved in bacteria
A5891_RS06800	COG3773	Cell wall hydrolase
A5891_RS06805	COG2244	polysaccharide biosynthetic process
A5891_RS06810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5891_RS06815	COG2217	Heavy metal translocating P-type atpase
A5891_RS06820	COG0006	proline dipeptidase activity
A5891_RS06825	COG1609	Transcriptional regulator
A5891_RS06830	COG3711	transcriptional antiterminator
A5891_RS06835	COG2190	(PTS) system
A5891_RS06835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5891_RS06835	COG1263	PTS System
A5891_RS06840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5891_RS06845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A5891_RS06855	COG1533	DNA photolyase activity
A5891_RS06860	COG0840	transmembrane signaling receptor activity
A5891_RS06865	COG2084	Dehydrogenase
A5891_RS06870	COG2340	Cysteine-rich secretory protein family
A5891_RS06875	COG0768	penicillin binding
A5891_RS06880	COG4191	Histidine kinase
A5891_RS06885	COG0436	Aminotransferase
A5891_RS06890	COG0835	chemotaxis
A5891_RS06890	COG0784	Response regulator, receiver
A5891_RS06900	COG2814	Major facilitator Superfamily
A5891_RS06905	COG1376	ErfK ybiS ycfS ynhG family protein
A5891_RS06910	COG1408	metallophosphoesterase
A5891_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS06925	COG2200	EAL domain
A5891_RS06930	COG4703	Protein of unknown function (DUF1797)
A5891_RS06935	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A5891_RS06945	COG0517	IMP dehydrogenase activity
A5891_RS06950	COG0583	DNA-binding transcription factor activity
A5891_RS06955	COG0716	FMN binding
A5891_RS06965	COG0716	FMN binding
A5891_RS06985	COG0668	transmembrane transport
A5891_RS06990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5891_RS07010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A5891_RS07015	COG0303	'Molybdopterin
A5891_RS07020	COG1763	Mo-molybdopterin cofactor biosynthetic process
A5891_RS07025	COG0314	molybdopterin synthase activity
A5891_RS07030	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A5891_RS07040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A5891_RS07045	COG1136	(ABC) transporter
A5891_RS07050	COG0577	efflux transmembrane transporter activity
A5891_RS07055	COG1349	DNA-binding transcription factor activity
A5891_RS07060	COG1105	Belongs to the carbohydrate kinase PfkB family
A5891_RS07065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5891_RS07065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5891_RS07065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5891_RS07070	COG0681	Belongs to the peptidase S26 family
A5891_RS07080	COG0488	(ABC) transporter
A5891_RS07085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A5891_RS07090	COG2309	aminopeptidase activity
A5891_RS07095	COG1077	Cell shape determining protein MreB Mrl
A5891_RS07100	COG2002	toxin-antitoxin pair type II binding
A5891_RS07105	COG3852	Histidine kinase
A5891_RS07110	COG2105	PFAM AIG2 family protein
A5891_RS07110	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A5891_RS07115	COG0569	domain protein
A5891_RS07125	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A5891_RS07135	COG0561	phosphatase activity
A5891_RS07140	COG0242	peptide deformylase activity
A5891_RS07150	COG0497	DNA recombination
A5891_RS07155	COG2070	2-Nitropropane dioxygenase
A5891_RS07155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A5891_RS07160	COG3321	synthase
A5891_RS07160	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS07160	COG4221	oxidoreductase activity
A5891_RS07160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS07165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS07165	COG3321	synthase
A5891_RS07165	COG4221	oxidoreductase activity
A5891_RS07165	COG0300	oxidoreductase activity
A5891_RS07170	COG3321	synthase
A5891_RS07170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS07170	COG4221	oxidoreductase activity
A5891_RS07175	COG0300	oxidoreductase activity
A5891_RS07175	COG3321	synthase
A5891_RS07175	COG4221	oxidoreductase activity
A5891_RS07175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS07180	COG4221	oxidoreductase activity
A5891_RS07180	COG3321	synthase
A5891_RS07180	COG0300	oxidoreductase activity
A5891_RS07180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS07185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS07185	COG0300	oxidoreductase activity
A5891_RS07185	COG4221	oxidoreductase activity
A5891_RS07185	COG3321	synthase
A5891_RS07190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS07190	COG3321	synthase
A5891_RS07190	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS07190	COG4221	oxidoreductase activity
A5891_RS07195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A5891_RS07200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A5891_RS07205	COG0022	dehydrogenase e1 component
A5891_RS07210	COG0508	dehydrogenase complex catalyzes the overall conversion of
A5891_RS07215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A5891_RS07220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5891_RS07230	COG1982	Orn Lys Arg decarboxylase major
A5891_RS07250	COG0483	inositol monophosphate 1-phosphatase activity
A5891_RS07260	COG3227	Zinc metalloprotease (Elastase)
A5891_RS07280	COG1217	gtp-binding protein TYPA
A5891_RS07290	COG4896	Protein conserved in bacteria
A5891_RS07300	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A5891_RS07305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A5891_RS07310	COG2066	Belongs to the glutaminase family
A5891_RS07320	COG0772	Belongs to the SEDS family
A5891_RS07325	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A5891_RS07340	COG2010	Cytochrome c
A5891_RS07340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A5891_RS07345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A5891_RS07350	COG1845	cytochrome c oxidase, subunit III
A5891_RS07355	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A5891_RS07360	COG3336	cytochrome c oxidase
A5891_RS07370	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A5891_RS07375	COG2340	Cysteine-rich secretory protein family
A5891_RS07390	COG3679	Belongs to the UPF0342 family
A5891_RS07400	COG0742	ribosomal rna small subunit methyltransferase
A5891_RS07410	COG3314	Sporulation integral membrane protein YlbJ
A5891_RS07415	COG1752	Esterase of the alpha-beta hydrolase superfamily
A5891_RS07420	COG3480	Lon protease (S16) C-terminal proteolytic domain
A5891_RS07430	COG1399	metal-binding, possibly nucleic acid-binding protein
A5891_RS07445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A5891_RS07465	COG4839	cell division protein FtsL
A5891_RS07470	COG0768	penicillin binding
A5891_RS07475	COG0768	penicillin binding
A5891_RS07495	COG0772	Belongs to the SEDS family
A5891_RS07510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A5891_RS07515	COG0849	cell division
A5891_RS07520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A5891_RS07525	COG1404	Belongs to the peptidase S8 family
A5891_RS07525	COG4412	M6 family metalloprotease domain protein
A5891_RS07535	COG1191	sigma factor activity
A5891_RS07540	COG1191	sigma factor activity
A5891_RS07545	COG1119	ATPase activity
A5891_RS07550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A5891_RS07555	COG1873	PFAM PRC-barrel domain
A5891_RS07560	COG1496	oxidoreductase activity
A5891_RS07565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A5891_RS07575	COG0762	integral membrane protein
A5891_RS07580	COG2302	S4 RNA-binding domain
A5891_RS07585	COG3599	regulation of cell shape
A5891_RS07595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A5891_RS07600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A5891_RS07610	COG0564	pseudouridine synthase activity
A5891_RS07620	COG2233	PERMEase
A5891_RS07630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A5891_RS07635	COG0505	Belongs to the CarA family
A5891_RS07640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A5891_RS07655	COG0284	orotidine-5'-phosphate decarboxylase activity
A5891_RS07660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A5891_RS07670	COG0306	phosphate transporter
A5891_RS07685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A5891_RS07690	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
A5891_RS07695	COG1648	precorrin-2 dehydrogenase activity
A5891_RS07710	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A5891_RS07715	COG1561	YicC-like family, N-terminal region
A5891_RS07725	COG0194	GDP metabolic process
A5891_RS07735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A5891_RS07740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A5891_RS07745	COG0242	peptide deformylase activity
A5891_RS07755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A5891_RS07755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A5891_RS07765	COG0631	protein serine/threonine phosphatase activity
A5891_RS07770	COG0515	serine threonine protein kinase
A5891_RS07770	COG2815	serine threonine protein kinase
A5891_RS07780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A5891_RS07785	COG1564	THIamine pyrophosphokinase
A5891_RS07800	COG1302	Protein conserved in bacteria
A5891_RS07805	COG1461	Dihydroxyacetone kinase
A5891_RS07810	COG1760	l-serine dehydratase
A5891_RS07815	COG1760	l-serine dehydratase
A5891_RS07820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A5891_RS07835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A5891_RS07840	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS07855	COG1196	nuclear chromosome segregation
A5891_RS07860	COG0552	protein localization to endoplasmic reticulum
A5891_RS07875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A5891_RS07885	COG1837	Belongs to the UPF0109 family
A5891_RS07910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A5891_RS07925	COG2257	FlhB HrpN YscU SpaS Family
A5891_RS07935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A5891_RS07940	COG0758	DNA mediated transformation
A5891_RS07945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A5891_RS07955	COG4974	Belongs to the 'phage' integrase family
A5891_RS07975	COG1815	bacterial-type flagellum-dependent cell motility
A5891_RS07980	COG1558	bacterial-type flagellum-dependent cell motility
A5891_RS07985	COG1677	Flagellar hook-basal body complex protein FliE
A5891_RS07990	COG1766	The M ring may be actively involved in energy transduction
A5891_RS07995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A5891_RS08000	COG1317	bacterial-type flagellum organization
A5891_RS08005	COG1157	protein secretion by the type III secretion system
A5891_RS08010	COG2882	bacterial-type flagellum organization
A5891_RS08015	COG3334	PFAM MgtE intracellular
A5891_RS08020	COG3144	bacterial-type flagellum assembly
A5891_RS08025	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A5891_RS08030	COG4786	Flagellar basal body rod
A5891_RS08035	COG1582	Flagellar protein (FlbD)
A5891_RS08040	COG1580	Controls the rotational direction of flagella during chemotaxis
A5891_RS08045	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A5891_RS08050	COG1776	CheC inhibitor of MCP methylation
A5891_RS08050	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A5891_RS08055	COG2201	protein-glutamate methylesterase activity
A5891_RS08060	COG3190	flagellar
A5891_RS08065	COG1338	Plays a role in the flagellum-specific transport system
A5891_RS08070	COG1987	bacterial-type flagellum assembly
A5891_RS08075	COG1684	flagellar biosynthetic protein fliR
A5891_RS08080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A5891_RS08085	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A5891_RS08090	COG1419	protein localization to endoplasmic reticulum
A5891_RS08095	COG0455	bacterial-type flagellum organization
A5891_RS08100	COG2201	protein-glutamate methylesterase activity
A5891_RS08105	COG0643	Histidine kinase
A5891_RS08105	COG2198	Histidine kinase
A5891_RS08110	COG0835	chemotaxis
A5891_RS08115	COG1776	CheC inhibitor of MCP methylation
A5891_RS08125	COG1191	sigma factor activity
A5891_RS08155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A5891_RS08160	COG4589	Belongs to the CDS family
A5891_RS08170	COG0750	zinc metalloprotease
A5891_RS08180	COG2176	DNA-directed DNA polymerase activity
A5891_RS08190	COG0195	Participates in both transcription termination and antitermination
A5891_RS08195	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A5891_RS08200	COG1358	cellular component organization or biogenesis
A5891_RS08210	COG1550	Protein conserved in bacteria
A5891_RS08225	COG0196	riboflavin kinase activity
A5891_RS08240	COG0726	polysaccharide deacetylase
A5891_RS08245	COG0612	Peptidase, M16
A5891_RS08250	COG1873	PFAM PRC-barrel domain
A5891_RS08255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A5891_RS08260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A5891_RS08265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A5891_RS08270	COG0527	aspartate kinase activity
A5891_RS08280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A5891_RS08285	COG0740	serine-type endopeptidase activity
A5891_RS08295	COG4980	gas vesicle protein
A5891_RS08295	COG1674	ftsk spoiiie
A5891_RS08300	COG2188	Transcriptional regulator
A5891_RS08305	COG2814	Major facilitator Superfamily
A5891_RS08310	COG1846	Transcriptional regulator
A5891_RS08315	COG2409	Drug exporters of the RND superfamily
A5891_RS08315	COG1033	growth of symbiont in host cell
A5891_RS08320	COG0612	Peptidase, M16
A5891_RS08325	COG0612	Peptidase, M16
A5891_RS08330	COG0300	oxidoreductase activity
A5891_RS08345	COG1426	Protein conserved in bacteria
A5891_RS08350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A5891_RS08365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A5891_RS08375	COG1692	metallophosphoesterase
A5891_RS08380	COG2359	stage V sporulation protein S
A5891_RS08400	COG4550	Control of competence regulator ComK, YlbF/YmcA
A5891_RS08445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS08450	COG3425	synthase
A5891_RS08455	COG1024	Enoyl-CoA hydratase
A5891_RS08460	COG1024	Enoyl-CoA hydratase
A5891_RS08465	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS08465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS08465	COG0300	oxidoreductase activity
A5891_RS08465	COG3321	synthase
A5891_RS08465	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS08470	COG4221	oxidoreductase activity
A5891_RS08470	COG0300	oxidoreductase activity
A5891_RS08470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS08470	COG3321	synthase
A5891_RS08475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS08475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5891_RS08475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS08475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS08475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5891_RS08475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS08475	COG3321	synthase
A5891_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS08475	COG3321	synthase
A5891_RS08480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS08480	COG3321	synthase
A5891_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS08480	COG4221	oxidoreductase activity
A5891_RS08485	COG3321	synthase
A5891_RS08485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS08485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A5891_RS08485	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A5891_RS08490	COG2124	cytochrome p450
A5891_RS08495	COG3209	COG3209 Rhs family protein
A5891_RS08500	COG3619	membrane
A5891_RS08510	COG1404	Belongs to the peptidase S8 family
A5891_RS08520	COG4195	phage-related replication protein
A5891_RS08525	COG1764	response to oxidative stress
A5891_RS08535	COG2076	Multidrug Resistance protein
A5891_RS08575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A5891_RS08580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A5891_RS08585	COG4112	unkown
A5891_RS08590	COG0860	N-Acetylmuramoyl-L-alanine amidase
A5891_RS08600	COG0464	growth
A5891_RS08605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A5891_RS08610	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A5891_RS08615	COG0789	Transcriptional regulator
A5891_RS08620	COG0174	glutamine synthetase
A5891_RS08660	COG2211	Major facilitator Superfamily
A5891_RS08665	COG3507	Belongs to the glycosyl hydrolase 43 family
A5891_RS08680	COG1070	Carbohydrate kinase
A5891_RS08685	COG3848	Pyruvate phosphate dikinase
A5891_RS08685	COG0574	Belongs to the PEP-utilizing enzyme family
A5891_RS08705	COG2318	DinB family
A5891_RS08710	COG1064	alcohol dehydrogenase
A5891_RS08715	COG4451	ribulose bisphosphate carboxylase, small
A5891_RS08715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A5891_RS08755	COG3397	chitin binding
A5891_RS08765	COG5434	Belongs to the glycosyl hydrolase 28 family
A5891_RS08770	COG0756	dUTP diphosphatase activity
A5891_RS08775	COG4195	phage-related replication protein
A5891_RS08805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A5891_RS08815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A5891_RS08835	COG0785	Cytochrome C biogenesis protein
A5891_RS08840	COG2201	protein-glutamate methylesterase activity
A5891_RS08845	COG4846	Membrane protein involved in cytochrome C biogenesis
A5891_RS08855	COG0071	Belongs to the small heat shock protein (HSP20) family
A5891_RS08870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A5891_RS08875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5891_RS08895	COG0824	Thioesterase
A5891_RS08905	COG4841	protein insertion into membrane
A5891_RS08915	COG1832	CoA-binding protein
A5891_RS08920	COG0187	DNA topoisomerase II activity
A5891_RS08925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A5891_RS08935	COG1115	amino acid carrier protein
A5891_RS08945	COG1063	alcohol dehydrogenase
A5891_RS08950	COG0800	Aldolase
A5891_RS08955	COG1312	Catalyzes the dehydration of D-mannonate
A5891_RS08960	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS08965	COG1609	Transcriptional regulator
A5891_RS08970	COG2271	Major facilitator Superfamily
A5891_RS09020	COG2205	protein histidine kinase activity
A5891_RS09025	COG0745	RESPONSE REGULATOR receiver
A5891_RS09035	COG3507	Belongs to the glycosyl hydrolase 43 family
A5891_RS09060	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS09065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A5891_RS09070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A5891_RS09075	COG2610	gluconate transmembrane transporter activity
A5891_RS09080	COG2124	cytochrome p450
A5891_RS09100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A5891_RS09110	COG2246	polysaccharide biosynthetic process
A5891_RS09120	COG0586	Pfam SNARE associated Golgi protein
A5891_RS09125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A5891_RS09130	COG1024	Enoyl-CoA hydratase
A5891_RS09135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A5891_RS09140	COG0511	ligase activity, forming carbon-carbon bonds
A5891_RS09145	COG0439	Biotin carboxylase
A5891_RS09150	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS09155	COG1960	acyl-CoA dehydrogenase activity
A5891_RS09160	COG1649	PFAM Uncharacterised BCR, COG1649
A5891_RS09170	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A5891_RS09170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS09175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS09180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS09190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS09195	COG2027	D-alanyl-D-alanine carboxypeptidase
A5891_RS09200	COG2017	converts alpha-aldose to the beta-anomer
A5891_RS09205	COG0534	Mate efflux family protein
A5891_RS09220	COG0582	viral genome integration into host DNA
A5891_RS09225	COG0166	Belongs to the GPI family
A5891_RS09230	COG0405	Gamma-glutamyltransferase
A5891_RS09235	COG2814	Major facilitator Superfamily
A5891_RS09240	COG0640	Transcriptional regulator
A5891_RS09245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A5891_RS09255	COG0604	alcohol dehydrogenase
A5891_RS09260	COG0493	'glutamate synthase
A5891_RS09265	COG0069	glutamate synthase activity
A5891_RS09265	COG0067	glutamate synthase
A5891_RS09265	COG0070	glutamate synthase
A5891_RS09270	COG0583	DNA-binding transcription factor activity
A5891_RS09275	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A5891_RS09290	COG0300	oxidoreductase activity
A5891_RS09295	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A5891_RS09305	COG2814	Major facilitator Superfamily
A5891_RS09310	COG1070	Carbohydrate kinase
A5891_RS09315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A5891_RS09320	COG0243	molybdopterin cofactor binding
A5891_RS09350	COG5444	nuclease activity
A5891_RS09355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A5891_RS09360	COG2207	Transcriptional regulator
A5891_RS09360	COG0662	Cupin 2, conserved barrel domain protein
A5891_RS09365	COG1309	transcriptional regulator
A5891_RS09370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A5891_RS09380	COG0640	Transcriptional regulator
A5891_RS09385	COG0741	lytic transglycosylase activity
A5891_RS09390	COG2322	membrane
A5891_RS09405	COG1619	proteins homologs of microcin C7 resistance protein MccF
A5891_RS09415	COG3584	3D domain protein
A5891_RS09415	COG1388	LysM domain
A5891_RS09420	COG0514	ATP-dependent DNA helicase (RecQ)
A5891_RS09430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A5891_RS09435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A5891_RS09450	COG0071	Belongs to the small heat shock protein (HSP20) family
A5891_RS09475	COG1012	belongs to the aldehyde dehydrogenase family
A5891_RS09480	COG1657	PFAM Prenyltransferase squalene oxidase
A5891_RS09485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A5891_RS09490	COG0733	neurotransmitter:sodium symporter activity
A5891_RS09495	COG0385	Bile acid
A5891_RS09500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A5891_RS09505	COG0508	dehydrogenase complex catalyzes the overall conversion of
A5891_RS09515	COG4548	von Willebrand factor, type A
A5891_RS09520	COG0714	Associated with various cellular activities
A5891_RS09525	COG2032	superoxide dismutase activity
A5891_RS09530	COG0791	NLP P60 protein
A5891_RS09530	COG1388	LysM domain
A5891_RS09535	COG1819	glycosyl
A5891_RS09540	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A5891_RS09545	COG0534	Mate efflux family protein
A5891_RS09550	COG1366	Belongs to the anti-sigma-factor antagonist family
A5891_RS09555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A5891_RS09560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A5891_RS09570	COG2962	Rard protein
A5891_RS09585	COG1942	4-Oxalocrotonate Tautomerase
A5891_RS09595	COG1733	regulation of RNA biosynthetic process
A5891_RS09600	COG0778	Nitroreductase
A5891_RS09605	COG0400	carboxylic ester hydrolase activity
A5891_RS09610	COG0346	lactoylglutathione lyase activity
A5891_RS09620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A5891_RS09630	COG2723	6-phospho-beta-galactosidase activity
A5891_RS09635	COG2188	Transcriptional regulator
A5891_RS09640	COG0793	Belongs to the peptidase S41A family
A5891_RS09640	COG3409	Peptidoglycan-binding domain 1 protein
A5891_RS09645	COG2226	methyltransferase
A5891_RS09655	COG1876	peptidase activity
A5891_RS09670	COG0671	phosphoesterase, PA-phosphatase related
A5891_RS09700	COG1509	lysine 2,3-aminomutase activity
A5891_RS09705	COG0456	acetyltransferase
A5891_RS09710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A5891_RS09715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A5891_RS09720	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A5891_RS09725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A5891_RS09730	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A5891_RS09740	COG0456	acetyltransferase
A5891_RS09745	COG0463	Glycosyl transferase, family 2
A5891_RS09760	COG4641	Protein conserved in bacteria
A5891_RS09770	COG1086	Polysaccharide biosynthesis protein
A5891_RS09795	COG0457	Tetratricopeptide repeat
A5891_RS09805	COG3391	amine dehydrogenase activity
A5891_RS09825	COG5444	nuclease activity
A5891_RS09830	COG4282	regulation of fungal-type cell wall biogenesis
A5891_RS09835	COG1525	nuclease
A5891_RS09840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A5891_RS09860	COG1846	Transcriptional regulator
A5891_RS09865	COG4698	Protein conserved in bacteria
A5891_RS09870	COG2755	lipolytic protein G-D-S-L family
A5891_RS09875	COG1999	signal sequence binding
A5891_RS09885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A5891_RS09890	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A5891_RS09895	COG1272	protein, Hemolysin III
A5891_RS09900	COG0204	Acyl-transferase
A5891_RS09905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A5891_RS09920	COG2136	Putative SAM-dependent methyltransferase
A5891_RS09920	COG2521	methyltransferase
A5891_RS09935	COG1413	lyase activity
A5891_RS09940	COG1418	mRNA catabolic process
A5891_RS09945	COG0386	Belongs to the glutathione peroxidase family
A5891_RS09955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A5891_RS09960	COG1278	Cold shock
A5891_RS09980	COG0328	RNA-DNA hybrid ribonuclease activity
A5891_RS09985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A5891_RS09990	COG0328	RNA-DNA hybrid ribonuclease activity
A5891_RS10000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A5891_RS10010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A5891_RS10015	COG1755	Isoprenylcysteine carboxyl methyltransferase
A5891_RS10020	COG3424	synthase
A5891_RS10040	COG1335	isochorismatase
A5891_RS10050	COG2233	PERMEase
A5891_RS10060	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A5891_RS10065	COG1199	ATP-dependent helicase activity
A5891_RS10075	COG0116	Belongs to the methyltransferase superfamily
A5891_RS10095	COG3359	exonuclease
A5891_RS10100	COG1111	helicase
A5891_RS10100	COG1205	dead DEAH box helicase
A5891_RS10105	COG2190	(PTS) system
A5891_RS10110	COG0071	Belongs to the small heat shock protein (HSP20) family
A5891_RS10150	COG4499	WXG100 protein secretion system (Wss), protein YukC
A5891_RS10150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A5891_RS10160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A5891_RS10165	COG3935	DnaD domain protein
A5891_RS10175	COG0436	Aminotransferase
A5891_RS10180	COG5353	protein conserved in bacteria
A5891_RS10190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A5891_RS10190	COG1199	ATP-dependent helicase activity
A5891_RS10220	COG0438	transferase activity, transferring glycosyl groups
A5891_RS10225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A5891_RS10240	COG1694	Mazg nucleotide pyrophosphohydrolase
A5891_RS10245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A5891_RS10260	COG4347	Protein of unknown function (DUF1405)
A5891_RS10265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A5891_RS10265	COG2010	Cytochrome c
A5891_RS10270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A5891_RS10275	COG0723	plastoquinol--plastocyanin reductase activity
A5891_RS10290	COG0457	Tetratricopeptide repeat
A5891_RS10300	COG0287	Prephenate dehydrogenase
A5891_RS10335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A5891_RS10340	COG4401	Chorismate mutase type I
A5891_RS10355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A5891_RS10360	COG0105	UTP biosynthetic process
A5891_RS10365	COG0142	geranyltranstransferase activity
A5891_RS10375	COG0142	geranyltranstransferase activity
A5891_RS10390	COG0776	regulation of translation
A5891_RS10395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A5891_RS10435	COG0539	negative regulation of cytoplasmic translation
A5891_RS10445	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
A5891_RS10450	COG2959	enzyme of heme biosynthesis
A5891_RS10455	COG3409	Peptidoglycan-binding domain 1 protein
A5891_RS10455	COG3773	Cell wall hydrolase
A5891_RS10460	COG2339	peptidase activity
A5891_RS10465	COG0492	ferredoxin-NADP+ reductase activity
A5891_RS10470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A5891_RS10475	COG4862	establishment of competence for transformation
A5891_RS10480	COG1408	metallophosphoesterase
A5891_RS10490	COG1388	LysM domain
A5891_RS10495	COG1266	CAAX protease self-immunity
A5891_RS10500	COG0514	ATP-dependent DNA helicase (RecQ)
A5891_RS10505	COG4955	Helix-turn-helix domain
A5891_RS10510	COG1141	Ferredoxin
A5891_RS10515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A5891_RS10520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A5891_RS10530	COG1595	DNA-templated transcription, initiation
A5891_RS10535	COG5002	protein histidine kinase activity
A5891_RS10540	COG0745	RESPONSE REGULATOR receiver
A5891_RS10545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A5891_RS10550	COG1333	cytochrome c biogenesis protein
A5891_RS10555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5891_RS10560	COG1187	pseudouridine synthase activity
A5891_RS10565	COG0700	Nucleoside recognition
A5891_RS10570	COG2715	membrane protein required for spore maturation
A5891_RS10575	COG1686	Belongs to the peptidase S11 family
A5891_RS10595	COG1547	Domain of unknown function (DUF309)
A5891_RS10600	COG0456	acetyltransferase
A5891_RS10615	COG0307	riboflavin synthase, alpha
A5891_RS10620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A5891_RS10620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A5891_RS10630	COG0681	Belongs to the peptidase S26 family
A5891_RS10640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A5891_RS10645	COG4086	secreted protein
A5891_RS10650	COG0019	diaminopimelate decarboxylase activity
A5891_RS10655	COG0697	spore germination
A5891_RS10670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A5891_RS10690	COG1191	sigma factor activity
A5891_RS10700	COG1366	Belongs to the anti-sigma-factor antagonist family
A5891_RS10705	COG1686	Belongs to the peptidase S11 family
A5891_RS10710	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A5891_RS10715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A5891_RS10720	COG4974	Belongs to the 'phage' integrase family
A5891_RS10730	COG0735	belongs to the Fur family
A5891_RS10735	COG1300	Membrane
A5891_RS10750	COG0281	malic enzyme
A5891_RS10755	COG1757	Na H antiporter
A5891_RS10760	COG1027	Aspartate ammonia-lyase
A5891_RS10765	COG0252	asparaginase activity
A5891_RS10770	COG1396	sequence-specific DNA binding
A5891_RS10775	COG1379	DNA repair
A5891_RS10780	COG0494	nUDIX hydrolase
A5891_RS10790	COG0667	Aldo Keto reductase
A5891_RS10800	COG1073	alpha beta
A5891_RS10810	COG4918	Iron-sulphur cluster biosynthesis
A5891_RS10815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A5891_RS10815	COG0456	acetyltransferase
A5891_RS10820	COG2329	Antibiotic biosynthesis monooxygenase
A5891_RS10825	COG0456	acetyltransferase
A5891_RS10830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A5891_RS10845	COG0628	permease
A5891_RS10850	COG0346	lactoylglutathione lyase activity
A5891_RS10860	COG3048	D-serine ammonia-lyase activity
A5891_RS10865	COG0300	oxidoreductase activity
A5891_RS10870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A5891_RS10875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A5891_RS10880	COG1024	Enoyl-CoA hydratase
A5891_RS10885	COG3425	synthase
A5891_RS10890	COG2124	cytochrome p450
A5891_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS10895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS10895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5891_RS10895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS10895	COG3321	synthase
A5891_RS10900	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS10900	COG3321	synthase
A5891_RS10900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS10900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5891_RS10900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS10905	COG0300	oxidoreductase activity
A5891_RS10905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS10905	COG3321	synthase
A5891_RS10905	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS10910	COG3321	synthase
A5891_RS10910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS10910	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS10910	COG0300	oxidoreductase activity
A5891_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS10915	COG3321	synthase
A5891_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS10915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS10915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5891_RS10915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS10920	COG0300	oxidoreductase activity
A5891_RS10920	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS10920	COG3321	synthase
A5891_RS10920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS10925	COG3321	synthase
A5891_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS10925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS10925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5891_RS10925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5891_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS10935	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS10950	COG2070	2-Nitropropane dioxygenase
A5891_RS10950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A5891_RS10955	COG0250	Participates in transcription elongation, termination and antitermination
A5891_RS10975	COG0596	Alpha beta hydrolase
A5891_RS10990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A5891_RS10995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A5891_RS11010	COG0706	membrane insertase activity
A5891_RS11015	COG2195	Cleaves the N-terminal amino acid of tripeptides
A5891_RS11020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A5891_RS11025	COG0346	lactoylglutathione lyase activity
A5891_RS11035	COG4129	membrane
A5891_RS11040	COG1126	abc transporter atp-binding protein
A5891_RS11045	COG0765	amino acid transport
A5891_RS11050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5891_RS11060	COG1597	lipid kinase activity
A5891_RS11065	COG0508	dehydrogenase complex catalyzes the overall conversion of
A5891_RS11070	COG0022	dehydrogenase e1 component
A5891_RS11075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A5891_RS11080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A5891_RS11085	COG3426	butyrate kinase activity
A5891_RS11090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A5891_RS11095	COG0280	phosphate acetyltransferase
A5891_RS11100	COG3829	transcription factor binding
A5891_RS11100	COG3290	protein histidine kinase activity
A5891_RS11110	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A5891_RS11115	COG2079	MmgE PrpD family protein
A5891_RS11120	COG0372	Belongs to the citrate synthase family
A5891_RS11125	COG1960	acyl-CoA dehydrogenase activity
A5891_RS11130	COG1250	3-hydroxyacyl-CoA dehydrogenase
A5891_RS11135	COG0183	Belongs to the thiolase family
A5891_RS11140	COG0584	glycerophosphoryl diester phosphodiesterase
A5891_RS11145	COG0860	N-Acetylmuramoyl-L-alanine amidase
A5891_RS11170	COG1902	pentaerythritol trinitrate reductase activity
A5891_RS11185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A5891_RS11190	COG0745	RESPONSE REGULATOR receiver
A5891_RS11195	COG0750	zinc metalloprotease
A5891_RS11200	COG0497	DNA recombination
A5891_RS11210	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A5891_RS11220	COG0142	geranyltranstransferase activity
A5891_RS11230	COG1570	exodeoxyribonuclease VII activity
A5891_RS11245	COG1302	Protein conserved in bacteria
A5891_RS11250	COG0439	Biotin carboxylase
A5891_RS11255	COG0511	ligase activity, forming carbon-carbon bonds
A5891_RS11295	COG3854	ATPases associated with a variety of cellular activities
A5891_RS11310	COG0006	proline dipeptidase activity
A5891_RS11320	COG3872	metal-dependent enzyme
A5891_RS11330	COG1752	Esterase of the alpha-beta hydrolase superfamily
A5891_RS11345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A5891_RS11365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A5891_RS11380	COG1396	sequence-specific DNA binding
A5891_RS11390	COG0681	Belongs to the peptidase S26 family
A5891_RS11415	COG4940	Competence protein ComGF
A5891_RS11425	COG4970	Tfp pilus assembly protein FimT
A5891_RS11430	COG4537	Required for transformation and DNA binding
A5891_RS11435	COG1459	type II secretion system
A5891_RS11440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A5891_RS11445	COG0598	Magnesium transport protein CorA
A5891_RS11450	COG1253	flavin adenine dinucleotide binding
A5891_RS11455	COG1366	Belongs to the anti-sigma-factor antagonist family
A5891_RS11465	COG1393	Belongs to the ArsC family
A5891_RS11475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A5891_RS11485	COG0011	TIGRFAM Protein of
A5891_RS11495	COG2866	Carboxypeptidase
A5891_RS11500	COG1940	carbohydrate kinase activity
A5891_RS11505	COG4483	Protein conserved in bacteria
A5891_RS11510	COG1757	Na H antiporter
A5891_RS11515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A5891_RS11525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A5891_RS11530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A5891_RS11535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A5891_RS11540	COG0581	inorganic phosphate transmembrane transporter activity
A5891_RS11545	COG0573	inorganic phosphate transmembrane transporter activity
A5891_RS11550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A5891_RS11555	COG0768	penicillin binding
A5891_RS11560	COG0477	Major facilitator Superfamily
A5891_RS11565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A5891_RS11570	COG2839	Protein conserved in bacteria
A5891_RS11575	COG5521	maltodextrose utilization protein MalA
A5891_RS11580	COG1388	LysM domain
A5891_RS11590	COG4709	membrane
A5891_RS11595	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
A5891_RS11600	COG0735	belongs to the Fur family
A5891_RS11605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A5891_RS11620	COG0513	Belongs to the DEAD box helicase family
A5891_RS11635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A5891_RS11640	COG2384	SAM-dependent methyltransferase
A5891_RS11645	COG2010	Cytochrome c
A5891_RS11650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A5891_RS11655	COG0358	DNA primase activity
A5891_RS11670	COG0517	IMP dehydrogenase activity
A5891_RS11675	COG0751	glycine-tRNA ligase activity
A5891_RS11695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A5891_RS11700	COG0295	cytidine deaminase activity
A5891_RS11705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A5891_RS11715	COG1480	7TM receptor with intracellular HD hydrolase
A5891_RS11720	COG1702	phosphate starvation-inducible protein PhoH
A5891_RS11725	COG0561	phosphatase activity
A5891_RS11740	COG4864	UPF0365 protein
A5891_RS11745	COG1030	water channel activity
A5891_RS11750	COG1610	YqeY-like protein
A5891_RS11760	COG1283	sodium-dependent phosphate transmembrane transporter activity
A5891_RS11765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A5891_RS11770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A5891_RS11800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A5891_RS11815	COG0860	N-Acetylmuramoyl-L-alanine amidase
A5891_RS11830	COG1466	dna polymerase III delta subunit
A5891_RS11840	COG2333	competence protein COMEC
A5891_RS11840	COG0658	competence protein
A5891_RS11845	COG2131	deaminase
A5891_RS11850	COG1596	polysaccharide export
A5891_RS11850	COG1555	photosystem II stabilization
A5891_RS11855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A5891_RS11860	COG2226	methyltransferase
A5891_RS11865	COG0799	negative regulation of ribosome biogenesis
A5891_RS11870	COG1713	HD superfamily hydrolase involved in NAD metabolism
A5891_RS11880	COG1534	Rna-binding protein
A5891_RS11885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A5891_RS11890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A5891_RS11895	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A5891_RS11905	COG2755	lipolytic protein G-D-S-L family
A5891_RS11915	COG0398	Pfam SNARE associated Golgi protein
A5891_RS11935	COG3628	GPW Gp25 family protein
A5891_RS11940	COG1794	racemase activity, acting on amino acids and derivatives
A5891_RS11950	COG0656	L-ascorbic acid biosynthetic process
A5891_RS11975	COG3677	Transposase
A5891_RS12005	COG5002	protein histidine kinase activity
A5891_RS12005	COG0642	Histidine kinase
A5891_RS12010	COG0745	RESPONSE REGULATOR receiver
A5891_RS12015	COG2311	Membrane
A5891_RS12020	COG0454	-acetyltransferase
A5891_RS12025	COG0563	adenylate kinase activity
A5891_RS12035	COG2814	Major facilitator Superfamily
A5891_RS12040	COG0456	acetyltransferase
A5891_RS12045	COG2318	DinB family
A5891_RS12055	COG0561	phosphatase activity
A5891_RS12060	COG0561	phosphatase activity
A5891_RS12070	COG1482	cell wall glycoprotein biosynthetic process
A5891_RS12075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5891_RS12075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5891_RS12075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5891_RS12080	COG3711	transcriptional antiterminator
A5891_RS12080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5891_RS12090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A5891_RS12095	COG0583	DNA-binding transcription factor activity
A5891_RS12100	COG2814	Major facilitator Superfamily
A5891_RS12105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A5891_RS12105	COG2124	cytochrome p450
A5891_RS12110	COG1309	transcriptional regulator
A5891_RS12115	COG2226	methyltransferase
A5891_RS12130	COG2116	formate transmembrane transporter activity
A5891_RS12135	COG5609	conserved protein (DUF2294)
A5891_RS12140	COG3383	formate dehydrogenase (NAD+) activity
A5891_RS12145	COG2427	Protein of unknown function (DUF1641)
A5891_RS12155	COG0626	cystathionine gamma-synthase activity
A5891_RS12160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A5891_RS12185	COG0768	penicillin binding
A5891_RS12200	COG0826	peptidase U32
A5891_RS12205	COG0826	peptidase U32
A5891_RS12210	COG4122	O-methyltransferase activity
A5891_RS12215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A5891_RS12240	COG0628	permease
A5891_RS12245	COG1126	abc transporter atp-binding protein
A5891_RS12250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5891_RS12255	COG0765	amino acid transport
A5891_RS12260	COG0765	amino acid transport
A5891_RS12275	COG3881	PFAM PRC-barrel domain
A5891_RS12280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A5891_RS12285	COG0457	Tetratricopeptide repeat
A5891_RS12295	COG1104	cysteine desulfurase activity
A5891_RS12300	COG1959	2 iron, 2 sulfur cluster binding
A5891_RS12305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A5891_RS12310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A5891_RS12330	COG4991	sh3 domain protein
A5891_RS12330	COG0860	N-Acetylmuramoyl-L-alanine amidase
A5891_RS12330	COG3103	Sh3 type 3 domain protein
A5891_RS12340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A5891_RS12350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A5891_RS12350	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A5891_RS12355	COG5416	Lipopolysaccharide assembly protein A domain
A5891_RS12360	COG0490	domain, Protein
A5891_RS12365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A5891_RS12365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A5891_RS12375	COG2244	polysaccharide biosynthetic process
A5891_RS12380	COG2323	membrane
A5891_RS12390	COG1862	Preprotein translocase
A5891_RS12430	COG1388	LysM domain
A5891_RS12440	COG0157	Belongs to the NadC ModD family
A5891_RS12445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A5891_RS12450	COG1104	cysteine desulfurase activity
A5891_RS12455	COG1827	regulation of RNA biosynthetic process
A5891_RS12460	COG0077	Prephenate dehydratase
A5891_RS12475	COG3290	protein histidine kinase activity
A5891_RS12480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A5891_RS12485	COG2868	ribosomal protein
A5891_RS12495	COG1994	Peptidase M50
A5891_RS12500	COG0739	heme binding
A5891_RS12505	COG2894	cell division
A5891_RS12510	COG0850	regulation of cytokinetic process
A5891_RS12515	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A5891_RS12525	COG1077	Cell shape determining protein MreB Mrl
A5891_RS12545	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A5891_RS12550	COG0285	dihydrofolate synthase activity
A5891_RS12555	COG0525	valine-tRNA ligase activity
A5891_RS12565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A5891_RS12570	COG1388	LysM domain
A5891_RS12580	COG0113	porphobilinogen synthase activity
A5891_RS12585	COG1587	Uroporphyrinogen-III synthase
A5891_RS12595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A5891_RS12615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A5891_RS12620	COG1067	ATP-dependent peptidase activity
A5891_RS12620	COG0470	DNA polymerase III
A5891_RS12635	COG1477	protein flavinylation
A5891_RS12635	COG0457	Tetratricopeptide repeat
A5891_RS12650	COG0473	3-isopropylmalate dehydrogenase activity
A5891_RS12665	COG0440	acetolactate synthase activity
A5891_RS12670	COG0028	Belongs to the TPP enzyme family
A5891_RS12695	COG0622	Phosphoesterase
A5891_RS12700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A5891_RS12710	COG5401	PFAM Sporulation and spore germination
A5891_RS12720	COG1846	Transcriptional regulator
A5891_RS12725	COG2197	response regulator
A5891_RS12730	COG0824	Thioesterase
A5891_RS12735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A5891_RS12740	COG1053	succinate dehydrogenase
A5891_RS12745	COG2009	succinate dehydrogenase
A5891_RS12750	COG1719	4-vinyl reductase, 4VR
A5891_RS12755	COG0527	aspartate kinase activity
A5891_RS12765	COG3118	belongs to the thioredoxin family
A5891_RS12770	COG3534	alpha-L-arabinofuranosidase
A5891_RS12775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A5891_RS12780	COG2086	electron transfer activity
A5891_RS12785	COG1024	Enoyl-CoA hydratase
A5891_RS12790	COG1309	transcriptional regulator
A5891_RS12795	COG0318	PFAM AMP-dependent synthetase and ligase
A5891_RS12805	COG3766	membrane
A5891_RS12815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A5891_RS12815	COG1796	DNA polymerase
A5891_RS12820	COG1286	toxin biosynthetic process
A5891_RS12835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A5891_RS12835	COG0072	phenylalanine-tRNA ligase activity
A5891_RS12840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A5891_RS12845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A5891_RS12855	COG3835	regulator
A5891_RS12860	COG0277	FAD linked oxidase domain protein
A5891_RS12865	COG0247	lactate metabolic process
A5891_RS12870	COG1966	Carbon starvation protein
A5891_RS12875	COG3534	alpha-L-arabinofuranosidase
A5891_RS12880	COG0395	ABC-type sugar transport system, permease component
A5891_RS12885	COG1175	transmembrane transport
A5891_RS12890	COG1653	transport
A5891_RS12900	COG0647	UMP catabolic process
A5891_RS12905	COG0235	Class ii aldolase
A5891_RS12910	COG1069	ribulokinase activity
A5891_RS12915	COG2160	L-arabinose isomerase activity
A5891_RS12920	COG3507	Belongs to the glycosyl hydrolase 43 family
A5891_RS12925	COG1363	Peptidase, m42
A5891_RS12935	COG3326	Membrane
A5891_RS12950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A5891_RS12955	COG1346	cytolysis
A5891_RS12960	COG1380	Effector of murein hydrolase LrgA
A5891_RS12965	COG3279	Response regulator of the LytR AlgR family
A5891_RS12970	COG3275	phosphorelay sensor kinase activity
A5891_RS12975	COG1011	Hydrolase
A5891_RS12990	COG0398	Pfam SNARE associated Golgi protein
A5891_RS12995	COG1484	DNA-dependent DNA replication
A5891_RS13000	COG3611	Membrane attachment protein
A5891_RS13015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A5891_RS13020	COG1733	regulation of RNA biosynthetic process
A5891_RS13025	COG2814	Major facilitator Superfamily
A5891_RS13030	COG0656	L-ascorbic acid biosynthetic process
A5891_RS13035	COG0237	dephospho-CoA kinase activity
A5891_RS13040	COG1971	Probably functions as a manganese efflux pump
A5891_RS13045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A5891_RS13050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A5891_RS13050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A5891_RS13055	COG5002	protein histidine kinase activity
A5891_RS13060	COG0745	RESPONSE REGULATOR receiver
A5891_RS13070	COG0538	isocitrate dehydrogenase activity
A5891_RS13075	COG0372	Belongs to the citrate synthase family
A5891_RS13095	COG0628	permease
A5891_RS13100	COG3030	protein affecting phage T7 exclusion by the F plasmid
A5891_RS13105	COG0469	pyruvate kinase activity
A5891_RS13130	COG0281	malic enzyme
A5891_RS13135	COG0587	DNA-directed DNA polymerase activity
A5891_RS13155	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A5891_RS13165	COG4109	DRTGG domain
A5891_RS13175	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS13190	COG0521	Mo-molybdopterin cofactor biosynthetic process
A5891_RS13200	COG0827	DNA restriction-modification system
A5891_RS13205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A5891_RS13210	COG3874	Sporulation protein YtfJ
A5891_RS13220	COG1714	RDD family
A5891_RS13225	COG0616	signal peptide processing
A5891_RS13230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A5891_RS13235	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A5891_RS13240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A5891_RS13255	COG1104	cysteine desulfurase activity
A5891_RS13260	COG1114	Component of the transport system for branched-chain amino acids
A5891_RS13270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A5891_RS13275	COG1309	transcriptional regulator
A5891_RS13280	COG1956	GAF domain-containing protein
A5891_RS13285	COG2203	Gaf domain
A5891_RS13285	COG2199	diguanylate cyclase activity
A5891_RS13295	COG1012	belongs to the aldehyde dehydrogenase family
A5891_RS13300	COG4282	regulation of fungal-type cell wall biogenesis
A5891_RS13330	COG1017	nitric oxide dioxygenase activity
A5891_RS13330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A5891_RS13340	COG0693	protein deglycase activity
A5891_RS13355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A5891_RS13360	COG1378	Sugar-specific transcriptional regulator TrmB
A5891_RS13380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A5891_RS13385	COG0454	-acetyltransferase
A5891_RS13390	COG0517	IMP dehydrogenase activity
A5891_RS13395	COG0123	including yeast histone deacetylase and acetoin utilization protein
A5891_RS13400	COG1360	Flagellar Motor Protein
A5891_RS13405	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A5891_RS13410	COG1609	Transcriptional regulator
A5891_RS13415	COG1605	Chorismate mutase
A5891_RS13415	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A5891_RS13420	COG3118	belongs to the thioredoxin family
A5891_RS13425	COG4980	gas vesicle protein
A5891_RS13430	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A5891_RS13440	COG1674	ftsk spoiiie
A5891_RS13445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A5891_RS13455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5891_RS13465	COG1363	Peptidase, m42
A5891_RS13470	COG5584	Small secreted protein
A5891_RS13475	COG0281	malic enzyme
A5891_RS13480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A5891_RS13495	COG0510	thiamine kinase activity
A5891_RS13500	COG1597	lipid kinase activity
A5891_RS13510	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A5891_RS13515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A5891_RS13520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A5891_RS13525	COG2252	PERMEase
A5891_RS13530	COG4473	ABC transporter
A5891_RS13535	COG1131	(ABC) transporter
A5891_RS13540	COG1349	DNA-binding transcription factor activity
A5891_RS13545	COG1187	pseudouridine synthase activity
A5891_RS13550	COG2244	polysaccharide biosynthetic process
A5891_RS13555	COG2081	HI0933 family
A5891_RS13560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A5891_RS13570	COG1609	Transcriptional regulator
A5891_RS13575	COG1653	transport
A5891_RS13580	COG1175	transmembrane transport
A5891_RS13585	COG0395	ABC-type sugar transport system, permease component
A5891_RS13590	COG1486	melibiose metabolic process
A5891_RS13600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A5891_RS13615	COG2202	Pas domain
A5891_RS13615	COG1366	Belongs to the anti-sigma-factor antagonist family
A5891_RS13620	COG2814	Major facilitator Superfamily
A5891_RS13625	COG5522	Integral membrane protein (intg_mem_TP0381)
A5891_RS13630	COG0577	efflux transmembrane transporter activity
A5891_RS13635	COG1136	(ABC) transporter
A5891_RS13640	COG2205	protein histidine kinase activity
A5891_RS13645	COG0745	RESPONSE REGULATOR receiver
A5891_RS13650	COG0577	efflux transmembrane transporter activity
A5891_RS13655	COG1136	(ABC) transporter
A5891_RS13675	COG1131	(ABC) transporter
A5891_RS13680	COG1725	Transcriptional regulator
A5891_RS13690	COG1242	4 iron, 4 sulfur cluster binding
A5891_RS13695	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A5891_RS13705	COG0584	glycerophosphoryl diester phosphodiesterase
A5891_RS13715	COG2267	carboxylic ester hydrolase activity
A5891_RS13720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A5891_RS13725	COG1113	amino acid transport
A5891_RS13730	COG0367	asparagine synthase
A5891_RS13750	COG1506	peptidase
A5891_RS13755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A5891_RS13760	COG1116	anion transmembrane transporter activity
A5891_RS13765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A5891_RS13770	COG0494	nUDIX hydrolase
A5891_RS13775	COG4824	toxin secretion phage lysis holin
A5891_RS13780	COG0783	Belongs to the Dps family
A5891_RS13805	COG0288	reversible hydration of carbon dioxide
A5891_RS13815	COG1271	oxidase subunit
A5891_RS13820	COG1294	oxidase, subunit
A5891_RS13835	COG4948	Mandelate Racemase Muconate Lactonizing
A5891_RS13845	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A5891_RS13850	COG0596	Alpha beta hydrolase
A5891_RS13860	COG1169	isochorismate synthase
A5891_RS13865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A5891_RS13870	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A5891_RS13995	COG3859	Proton-coupled thiamine transporter YuaJ
A5891_RS14000	COG2268	Band 7 protein
A5891_RS14005	COG1585	Membrane protein implicated in regulation of membrane protease activity
A5891_RS14010	COG2318	DinB family
A5891_RS14020	COG1454	alcohol dehydrogenase
A5891_RS14025	COG1012	belongs to the aldehyde dehydrogenase family
A5891_RS14030	COG1510	regulation of RNA biosynthetic process
A5891_RS14040	COG0569	domain protein
A5891_RS14045	COG1705	Flagellar rod assembly protein muramidase FlgJ
A5891_RS14050	COG1017	nitric oxide dioxygenase activity
A5891_RS14050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A5891_RS14075	COG0628	permease
A5891_RS14080	COG0673	inositol 2-dehydrogenase activity
A5891_RS14085	COG0693	protein deglycase activity
A5891_RS14090	COG0840	transmembrane signaling receptor activity
A5891_RS14095	COG0840	transmembrane signaling receptor activity
A5891_RS14100	COG0840	transmembrane signaling receptor activity
A5891_RS14105	COG0840	transmembrane signaling receptor activity
A5891_RS14120	COG2070	2-Nitropropane dioxygenase
A5891_RS14125	COG0432	Pfam Uncharacterised protein family UPF0047
A5891_RS14130	COG0366	Alpha amylase catalytic
A5891_RS14135	COG1253	flavin adenine dinucleotide binding
A5891_RS14140	COG2738	Putative neutral zinc metallopeptidase
A5891_RS14155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A5891_RS14180	COG1335	isochorismatase
A5891_RS14185	COG1979	alcohol dehydrogenase
A5891_RS14190	COG1979	alcohol dehydrogenase
A5891_RS14195	COG2155	Conserved Protein
A5891_RS14200	COG1098	S1 RNA binding domain
A5891_RS14205	COG0436	Aminotransferase
A5891_RS14210	COG1522	sequence-specific DNA binding
A5891_RS14215	COG2267	carboxylic ester hydrolase activity
A5891_RS14225	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A5891_RS14230	COG2205	protein histidine kinase activity
A5891_RS14240	COG5018	Exonuclease
A5891_RS14245	COG2814	Major facilitator Superfamily
A5891_RS14250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A5891_RS14255	COG3011	Protein conserved in bacteria
A5891_RS14265	COG3290	protein histidine kinase activity
A5891_RS14270	COG4565	transcriptional regulatory protein
A5891_RS14275	COG1744	ABC transporter substrate-binding protein PnrA-like
A5891_RS14280	COG3845	ABC transporter
A5891_RS14285	COG4603	Belongs to the binding-protein-dependent transport system permease family
A5891_RS14290	COG1079	Belongs to the binding-protein-dependent transport system permease family
A5891_RS14300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A5891_RS14300	COG2111	Na H antiporter
A5891_RS14305	COG2111	Na H antiporter
A5891_RS14310	COG1006	Multisubunit Na H antiporter MnhC subunit
A5891_RS14315	COG0651	ATP synthesis coupled electron transport
A5891_RS14320	COG1863	multisubunit Na H antiporter MnhE subunit
A5891_RS14325	COG2212	antiporter activity
A5891_RS14330	COG1320	monovalent cation:proton antiporter activity
A5891_RS14335	COG2050	protein possibly involved in aromatic compounds catabolism
A5891_RS14340	COG2197	response regulator
A5891_RS14345	COG4585	Histidine kinase
A5891_RS14370	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A5891_RS14375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A5891_RS14380	COG1335	isochorismatase
A5891_RS14385	COG5506	Protein of unknown function (DUF1694)
A5891_RS14400	COG0628	permease
A5891_RS14410	COG1418	mRNA catabolic process
A5891_RS14415	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS14425	COG1511	domain protein
A5891_RS14430	COG1674	ftsk spoiiie
A5891_RS14430	COG0433	COG0433 Predicted ATPase
A5891_RS14435	COG4499	WXG100 protein secretion system (Wss), protein YukC
A5891_RS14440	COG5417	Belongs to the EsaB family
A5891_RS14445	COG4842	Belongs to the WXG100 family
A5891_RS14450	COG2508	Transcriptional regulator
A5891_RS14450	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A5891_RS14455	COG0686	Belongs to the AlaDH PNT family
A5891_RS14460	COG5634	Uncharacterized conserved protein (DUF2278)
A5891_RS14465	COG3251	PFAM MbtH domain protein
A5891_RS14470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5891_RS14475	COG3433	isochorismatase activity
A5891_RS14475	COG1535	isochorismatase
A5891_RS14480	COG1021	2,3-dihydroxybenzoate-AMP ligase
A5891_RS14485	COG1169	isochorismate synthase
A5891_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS14495	COG2819	hydrolase of the alpha beta superfamily
A5891_RS14500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A5891_RS14505	COG1268	BioY protein
A5891_RS14510	COG2056	Na+-H+ antiporter family
A5891_RS14520	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A5891_RS14525	COG3584	3D domain protein
A5891_RS14535	COG1252	NADH dehydrogenase
A5891_RS14565	COG1131	(ABC) transporter
A5891_RS14585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A5891_RS14590	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A5891_RS14595	COG0316	Belongs to the HesB IscA family
A5891_RS14605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A5891_RS14615	COG1252	NADH dehydrogenase
A5891_RS14620	COG4837	Protein of unknown function (DUF1462)
A5891_RS14625	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A5891_RS14630	COG0823	Involved in the tonB-independent uptake of proteins
A5891_RS14630	COG4946	Tricorn protease homolog
A5891_RS14630	COG1506	peptidase
A5891_RS14640	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A5891_RS14645	COG0460	homoserine dehydrogenase
A5891_RS14650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A5891_RS14655	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A5891_RS14660	COG0647	UMP catabolic process
A5891_RS14665	COG2445	Protein of unknown function DUF86
A5891_RS14670	COG4470	Protein conserved in bacteria
A5891_RS14680	COG0739	heme binding
A5891_RS14690	COG0737	Belongs to the 5'-nucleotidase family
A5891_RS14695	COG0730	response to heat
A5891_RS14700	COG1801	Protein of unknown function DUF72
A5891_RS14715	COG2508	Transcriptional regulator
A5891_RS14740	COG2814	Major facilitator Superfamily
A5891_RS14745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A5891_RS14750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A5891_RS14755	COG2356	endonuclease I
A5891_RS14760	COG3842	ATPase activity
A5891_RS14765	COG2188	Transcriptional regulator
A5891_RS14770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5891_RS14775	COG0395	ABC-type sugar transport system, permease component
A5891_RS14780	COG1175	transmembrane transport
A5891_RS14785	COG1653	transport
A5891_RS14790	COG2222	sugar isomerase
A5891_RS14795	COG0789	Transcriptional regulator
A5891_RS14820	COG0322	excinuclease ABC activity
A5891_RS14825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A5891_RS14845	COG3409	Peptidoglycan-binding domain 1 protein
A5891_RS14850	COG0719	Fe-S assembly protein
A5891_RS14855	COG0822	iron-sulfur transferase activity
A5891_RS14860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A5891_RS14865	COG0719	Fe-S assembly protein
A5891_RS14870	COG0396	ATPase activity
A5891_RS14875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A5891_RS14880	COG1464	Belongs to the NlpA lipoprotein family
A5891_RS14885	COG2011	ABC-type metal ion transport system permease component
A5891_RS14890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A5891_RS14900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5891_RS14905	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A5891_RS14920	COG1393	Belongs to the ArsC family
A5891_RS14925	COG1960	acyl-CoA dehydrogenase activity
A5891_RS14930	COG0183	Belongs to the thiolase family
A5891_RS14935	COG1250	3-hydroxyacyl-CoA dehydrogenase
A5891_RS14935	COG1024	Enoyl-CoA hydratase
A5891_RS14955	COG5577	PFAM Coat F domain
A5891_RS14960	COG1846	Transcriptional regulator
A5891_RS14965	COG0477	Major facilitator Superfamily
A5891_RS14970	COG1942	4-Oxalocrotonate Tautomerase
A5891_RS14975	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS14980	COG0583	DNA-binding transcription factor activity
A5891_RS14985	COG0583	DNA-binding transcription factor activity
A5891_RS15010	COG1120	ATPase activity
A5891_RS15025	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS15030	COG0783	Belongs to the Dps family
A5891_RS15035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A5891_RS15040	COG0745	RESPONSE REGULATOR receiver
A5891_RS15045	COG2205	protein histidine kinase activity
A5891_RS15045	COG2770	Histidine kinase
A5891_RS15050	COG1309	transcriptional regulator
A5891_RS15055	COG0114	fumarate hydratase activity
A5891_RS15065	COG0697	spore germination
A5891_RS15070	COG0814	amino acid
A5891_RS15080	COG2197	response regulator
A5891_RS15085	COG4585	Histidine kinase
A5891_RS15090	COG4758	membrane
A5891_RS15095	COG3595	metallopeptidase activity
A5891_RS15100	COG1842	Phage shock protein A
A5891_RS15105	COG4758	membrane
A5891_RS15110	COG2814	Major facilitator Superfamily
A5891_RS15115	COG2096	Adenosyltransferase
A5891_RS15120	COG1120	ATPase activity
A5891_RS15125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5891_RS15130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A5891_RS15135	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS15140	COG3386	PFAM SMP-30 Gluconolaconase
A5891_RS15145	COG2205	protein histidine kinase activity
A5891_RS15150	COG0745	RESPONSE REGULATOR receiver
A5891_RS15160	COG1191	sigma factor activity
A5891_RS15170	COG2140	Oxalate decarboxylase
A5891_RS15180	COG1120	ATPase activity
A5891_RS15185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5891_RS15190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5891_RS15195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A5891_RS15200	COG0531	amino acid
A5891_RS15210	COG1988	membrane-bound metal-dependent
A5891_RS15215	COG1368	sulfuric ester hydrolase activity
A5891_RS15220	COG1910	domain protein
A5891_RS15225	COG0725	ABC transporter, periplasmic molybdate-binding protein
A5891_RS15230	COG4149	molybdate abc transporter
A5891_RS15235	COG2197	response regulator
A5891_RS15240	COG3850	Histidine kinase
A5891_RS15245	COG1131	(ABC) transporter
A5891_RS15255	COG0842	Transport permease protein
A5891_RS15260	COG0656	L-ascorbic acid biosynthetic process
A5891_RS15285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A5891_RS15290	COG3973	AAA domain
A5891_RS15295	COG2860	membrane
A5891_RS15305	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A5891_RS15310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A5891_RS15315	COG2217	Heavy metal translocating P-type atpase
A5891_RS15320	COG2217	Heavy metal translocating P-type atpase
A5891_RS15325	COG2608	mercury ion transmembrane transporter activity
A5891_RS15330	COG1937	Protein conserved in bacteria
A5891_RS15335	COG0673	inositol 2-dehydrogenase activity
A5891_RS15345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A5891_RS15350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A5891_RS15355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A5891_RS15360	COG1126	abc transporter atp-binding protein
A5891_RS15365	COG0765	amino acid transport
A5891_RS15370	COG0765	amino acid transport
A5891_RS15375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5891_RS15380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5891_RS15385	COG0454	-acetyltransferase
A5891_RS15390	COG0583	DNA-binding transcription factor activity
A5891_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS15425	COG4974	Belongs to the 'phage' integrase family
A5891_RS15440	COG0557	exoribonuclease II activity
A5891_RS15445	COG1647	Serine aminopeptidase, S33
A5891_RS15450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A5891_RS15455	COG1476	TRANSCRIPTIONal
A5891_RS15460	COG1396	sequence-specific DNA binding
A5891_RS15465	COG1396	sequence-specific DNA binding
A5891_RS15470	COG1733	regulation of RNA biosynthetic process
A5891_RS15495	COG1131	(ABC) transporter
A5891_RS15500	COG1174	glycine betaine transport
A5891_RS15505	COG1732	Glycine betaine
A5891_RS15510	COG1174	glycine betaine transport
A5891_RS15515	COG1125	glycine betaine transport
A5891_RS15515	COG0517	IMP dehydrogenase activity
A5891_RS15520	COG1510	regulation of RNA biosynthetic process
A5891_RS15525	COG1174	glycine betaine transport
A5891_RS15530	COG1732	Glycine betaine
A5891_RS15535	COG1174	glycine betaine transport
A5891_RS15540	COG0517	IMP dehydrogenase activity
A5891_RS15540	COG1125	glycine betaine transport
A5891_RS15545	COG1510	regulation of RNA biosynthetic process
A5891_RS15550	COG2095	MarC family integral membrane protein
A5891_RS15555	COG3064	Membrane
A5891_RS15560	COG4640	response to antibiotic
A5891_RS15565	COG0456	acetyltransferase
A5891_RS15580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A5891_RS15600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5891_RS15605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A5891_RS15615	COG2234	aminopeptidase activity
A5891_RS15635	COG0126	phosphoglycerate kinase activity
A5891_RS15645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A5891_RS15650	COG2390	Transcriptional regulator
A5891_RS15655	COG2814	Major facilitator Superfamily
A5891_RS15660	COG1609	Transcriptional regulator
A5891_RS15665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A5891_RS15675	COG0583	DNA-binding transcription factor activity
A5891_RS15680	COG0697	spore germination
A5891_RS15685	COG1113	amino acid transport
A5891_RS15690	COG1609	Transcriptional regulator
A5891_RS15700	COG0561	phosphatase activity
A5891_RS15705	COG1737	Transcriptional regulator
A5891_RS15710	COG1070	Carbohydrate kinase
A5891_RS15745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A5891_RS15750	COG2186	Transcriptional regulator
A5891_RS15755	COG1620	l-lactate permease
A5891_RS15760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A5891_RS15770	COG5039	Polysaccharide pyruvyl transferase
A5891_RS15775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A5891_RS15780	COG0110	maltose O-acetyltransferase activity
A5891_RS15785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A5891_RS15790	COG2244	polysaccharide biosynthetic process
A5891_RS15795	COG1216	Glycosyl transferase, family 2
A5891_RS15800	COG5039	Polysaccharide pyruvyl transferase
A5891_RS15805	COG1216	Glycosyl transferase, family 2
A5891_RS15815	COG0438	transferase activity, transferring glycosyl groups
A5891_RS15820	COG1215	transferase activity, transferring glycosyl groups
A5891_RS15825	COG0438	transferase activity, transferring glycosyl groups
A5891_RS15830	COG1086	Polysaccharide biosynthesis protein
A5891_RS15835	COG0489	protein tyrosine kinase activity
A5891_RS15840	COG3944	biosynthesis protein
A5891_RS15845	COG1396	sequence-specific DNA binding
A5891_RS15850	COG2272	Belongs to the type-B carboxylesterase lipase family
A5891_RS15855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A5891_RS15860	COG2364	Membrane
A5891_RS15865	COG0456	acetyltransferase
A5891_RS15870	COG3479	Phenolic acid decarboxylase
A5891_RS15915	COG2223	nitrite transmembrane transporter activity
A5891_RS15920	COG1609	Transcriptional regulator
A5891_RS15930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A5891_RS15935	COG0366	Alpha amylase catalytic
A5891_RS15940	COG1554	hydrolase, family 65, central catalytic
A5891_RS15945	COG5521	maltodextrose utilization protein MalA
A5891_RS15950	COG3833	ABC-type maltose transport systems, permease component
A5891_RS15955	COG1175	transmembrane transport
A5891_RS15960	COG2182	Extracellular solute-binding protein
A5891_RS15965	COG0366	Alpha amylase catalytic
A5891_RS15970	COG1609	Transcriptional regulator
A5891_RS15975	COG1611	Belongs to the LOG family
A5891_RS15980	COG1694	Mazg nucleotide pyrophosphohydrolase
A5891_RS15985	COG0659	secondary active sulfate transmembrane transporter activity
A5891_RS15990	COG0288	reversible hydration of carbon dioxide
A5891_RS16000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A5891_RS16005	COG4290	ribonuclease
A5891_RS16010	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A5891_RS16015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5891_RS16025	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A5891_RS16035	COG1051	belongs to the nudix hydrolase family
A5891_RS16040	COG0492	ferredoxin-NADP+ reductase activity
A5891_RS16045	COG0791	NLP P60 protein
A5891_RS16045	COG3883	PFAM NLP P60 protein
A5891_RS16050	COG0457	Tetratricopeptide repeat
A5891_RS16055	COG5002	protein histidine kinase activity
A5891_RS16060	COG0745	RESPONSE REGULATOR receiver
A5891_RS16065	COG1132	(ABC) transporter
A5891_RS16070	COG0140	phosphoribosyl-ATP diphosphatase activity
A5891_RS16070	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A5891_RS16095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A5891_RS16110	COG4990	cell redox homeostasis
A5891_RS16115	COG0110	maltose O-acetyltransferase activity
A5891_RS16135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A5891_RS16145	COG2188	Transcriptional regulator
A5891_RS16150	COG1309	transcriptional regulator
A5891_RS16155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A5891_RS16160	COG1950	PFAM Membrane protein of
A5891_RS16165	COG1983	PspC domain protein
A5891_RS16170	COG3595	metallopeptidase activity
A5891_RS16185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A5891_RS16195	COG4897	Protein conserved in bacteria
A5891_RS16200	COG3848	Pyruvate phosphate dikinase
A5891_RS16200	COG0574	Belongs to the PEP-utilizing enzyme family
A5891_RS16205	COG1309	transcriptional regulator
A5891_RS16210	COG2814	Major facilitator Superfamily
A5891_RS16225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A5891_RS16235	COG0793	Belongs to the peptidase S41A family
A5891_RS16235	COG3409	Peptidoglycan-binding domain 1 protein
A5891_RS16240	COG3420	alginic acid biosynthetic process
A5891_RS16245	COG2177	Part of the ABC transporter FtsEX involved in
A5891_RS16250	COG2884	Cell division ATP-binding protein ftsE
A5891_RS16255	COG2010	Cytochrome c
A5891_RS16260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A5891_RS16265	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A5891_RS16275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A5891_RS16290	COG1516	flagellar protein fliS
A5891_RS16295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A5891_RS16300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A5891_RS16320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A5891_RS16325	COG1256	bacterial-type flagellum assembly
A5891_RS16325	COG4786	Flagellar basal body rod
A5891_RS16330	COG3418	PFAM FlgN family protein
A5891_RS16335	COG2747	anti-sigma28 factor FlgM
A5891_RS16345	COG1040	competence protein
A5891_RS16355	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A5891_RS16360	COG1307	EDD domain protein, DegV family
A5891_RS16365	COG2197	response regulator
A5891_RS16370	COG4585	Histidine kinase
A5891_RS16375	COG1739	Uncharacterized protein family UPF0029
A5891_RS16380	COG1316	TRANSCRIPTIONal
A5891_RS16385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A5891_RS16390	COG0438	transferase activity, transferring glycosyl groups
A5891_RS16395	COG1215	transferase activity, transferring glycosyl groups
A5891_RS16400	COG3206	protein involved in exopolysaccharide biosynthesis
A5891_RS16405	COG3307	-O-antigen
A5891_RS16410	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A5891_RS16415	COG0438	transferase activity, transferring glycosyl groups
A5891_RS16415	COG0297	glycogen (starch) synthase activity
A5891_RS16420	COG2244	polysaccharide biosynthetic process
A5891_RS16430	COG0860	N-Acetylmuramoyl-L-alanine amidase
A5891_RS16430	COG2247	cell wall binding repeat
A5891_RS16435	COG2247	cell wall binding repeat
A5891_RS16435	COG2385	sporulation resulting in formation of a cellular spore
A5891_RS16445	COG1316	TRANSCRIPTIONal
A5891_RS16450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A5891_RS16455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A5891_RS16460	COG1134	teichoic acid transport
A5891_RS16465	COG1682	transport, permease protein
A5891_RS16470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A5891_RS16480	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A5891_RS16485	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A5891_RS16490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A5891_RS16495	COG4193	domain, Protein
A5891_RS16500	COG1482	cell wall glycoprotein biosynthetic process
A5891_RS16505	COG0697	spore germination
A5891_RS16510	COG0814	amino acid
A5891_RS16520	COG1215	transferase activity, transferring glycosyl groups
A5891_RS16525	COG2814	Major facilitator Superfamily
A5891_RS16530	COG1316	TRANSCRIPTIONal
A5891_RS16535	COG0561	phosphatase activity
A5891_RS16540	COG2433	Pfam Transposase IS66
A5891_RS16545	COG0791	NLP P60 protein
A5891_RS16550	COG2843	Capsule synthesis protein
A5891_RS16560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A5891_RS16565	COG0697	spore germination
A5891_RS16570	COG0814	amino acid
A5891_RS16580	COG1609	Transcriptional regulator
A5891_RS16585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5891_RS16595	COG1129	ABC transporter
A5891_RS16600	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5891_RS16605	COG1879	ABC-type sugar transport system periplasmic component
A5891_RS16610	COG3103	Sh3 type 3 domain protein
A5891_RS16615	COG2249	NAD(P)H dehydrogenase (quinone) activity
A5891_RS16620	COG3527	Alpha-acetolactate decarboxylase
A5891_RS16625	COG0028	Belongs to the TPP enzyme family
A5891_RS16630	COG0583	DNA-binding transcription factor activity
A5891_RS16635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A5891_RS16650	COG5337	Spore coat protein CotH
A5891_RS16660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A5891_RS16665	COG0405	Gamma-glutamyltransferase
A5891_RS16670	COG1522	sequence-specific DNA binding
A5891_RS16675	COG2059	Chromate
A5891_RS16680	COG2059	Chromate
A5891_RS16690	COG0655	NAD(P)H dehydrogenase (quinone) activity
A5891_RS16695	COG0583	DNA-binding transcription factor activity
A5891_RS16730	COG5444	nuclease activity
A5891_RS16745	COG3878	Protein conserved in bacteria
A5891_RS16750	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A5891_RS16755	COG4464	protein tyrosine phosphatase activity
A5891_RS16760	COG0489	protein tyrosine kinase activity
A5891_RS16765	COG3944	biosynthesis protein
A5891_RS16770	COG4715	Zinc finger, swim domain protein
A5891_RS16775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A5891_RS16780	COG0561	phosphatase activity
A5891_RS16785	COG1349	DNA-binding transcription factor activity
A5891_RS16790	COG0629	single-stranded DNA binding
A5891_RS16815	COG0457	Tetratricopeptide repeat
A5891_RS16820	COG4786	Flagellar basal body rod
A5891_RS16825	COG4786	Flagellar basal body rod
A5891_RS16830	COG1077	Cell shape determining protein MreB Mrl
A5891_RS16835	COG1609	Transcriptional regulator
A5891_RS16840	COG1846	Transcriptional regulator
A5891_RS16845	COG2814	Major facilitator Superfamily
A5891_RS16850	COG1953	Uracil, thiamine, allantoin
A5891_RS16855	COG0477	Major facilitator Superfamily
A5891_RS16860	COG1335	isochorismatase
A5891_RS16865	COG0004	ammonium transporteR
A5891_RS16870	COG0347	Belongs to the P(II) protein family
A5891_RS16875	COG0772	Belongs to the SEDS family
A5891_RS16880	COG0671	phosphoesterase, PA-phosphatase related
A5891_RS16890	COG0739	heme binding
A5891_RS16895	COG1247	-acetyltransferase
A5891_RS16910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A5891_RS16925	COG0726	polysaccharide deacetylase
A5891_RS16935	COG1959	2 iron, 2 sulfur cluster binding
A5891_RS16950	COG0831	urea catabolic process
A5891_RS16955	COG3237	CsbD-like
A5891_RS16960	COG1994	Peptidase M50
A5891_RS16965	COG0457	Tetratricopeptide repeat
A5891_RS16975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A5891_RS16980	COG2304	oxidoreductase activity
A5891_RS16985	COG2304	oxidoreductase activity
A5891_RS16990	COG2385	sporulation resulting in formation of a cellular spore
A5891_RS16995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A5891_RS17005	COG4836	Membrane
A5891_RS17075	COG0698	ribose 5-phosphate isomerase
A5891_RS17080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A5891_RS17090	COG0009	L-threonylcarbamoyladenylate synthase
A5891_RS17095	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A5891_RS17115	COG2890	protein-(glutamine-N5) methyltransferase activity
A5891_RS17120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A5891_RS17125	COG0346	lactoylglutathione lyase activity
A5891_RS17130	COG0789	Transcriptional regulator
A5891_RS17135	COG0679	Auxin Efflux Carrier
A5891_RS17140	COG0281	malic enzyme
A5891_RS17155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A5891_RS17160	COG1494	fructose-1,6-bisphosphatase
A5891_RS17165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A5891_RS17175	COG0191	fructose-bisphosphate aldolase activity
A5891_RS17180	COG2204	response regulator
A5891_RS17185	COG4821	SIS domain
A5891_RS17200	COG0247	lactate metabolic process
A5891_RS17200	COG2181	nitrate reductase activity
A5891_RS17205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A5891_RS17220	COG1132	(ABC) transporter
A5891_RS17225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A5891_RS17235	COG2181	nitrate reductase activity
A5891_RS17240	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A5891_RS17245	COG1140	nitrate reductase beta subunit
A5891_RS17250	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A5891_RS17255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A5891_RS17265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A5891_RS17270	COG2223	nitrite transmembrane transporter activity
A5891_RS17280	COG4506	Protein conserved in bacteria
A5891_RS17290	COG3391	amine dehydrogenase activity
A5891_RS17295	COG3391	amine dehydrogenase activity
A5891_RS17300	COG0457	Tetratricopeptide repeat
A5891_RS17305	COG0010	Belongs to the arginase family
A5891_RS17310	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A5891_RS17315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A5891_RS17330	COG1994	Peptidase M50
A5891_RS17335	COG1942	4-Oxalocrotonate Tautomerase
A5891_RS17340	COG1846	Transcriptional regulator
A5891_RS17345	COG0531	amino acid
A5891_RS17350	COG3465	dGTPase activity
A5891_RS17355	COG1078	dGTPase activity
A5891_RS17370	COG1695	Transcriptional regulator
A5891_RS17380	COG1131	(ABC) transporter
A5891_RS17385	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A5891_RS17415	COG0583	DNA-binding transcription factor activity
A5891_RS17420	COG2855	membrane
A5891_RS17425	COG0280	phosphate acetyltransferase
A5891_RS17435	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS17440	COG0436	Aminotransferase
A5891_RS17470	COG2814	Major facilitator Superfamily
A5891_RS17475	COG2814	Major facilitator Superfamily
A5891_RS17480	COG0833	amino acid
A5891_RS17485	COG4187	Peptidase family M20/M25/M40
A5891_RS17490	COG1012	belongs to the aldehyde dehydrogenase family
A5891_RS17495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A5891_RS17500	COG2205	protein histidine kinase activity
A5891_RS17505	COG0745	RESPONSE REGULATOR receiver
A5891_RS17520	COG1131	(ABC) transporter
A5891_RS17525	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A5891_RS17530	COG1091	dTDP-4-dehydrorhamnose reductase activity
A5891_RS17535	COG1088	dTDP-glucose 4,6-dehydratase activity
A5891_RS17540	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A5891_RS17545	COG3980	spore coat polysaccharide biosynthesis protein
A5891_RS17550	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
A5891_RS17555	COG2089	acid synthase
A5891_RS17560	COG0456	acetyltransferase
A5891_RS17565	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A5891_RS17570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A5891_RS17575	COG0463	Glycosyl transferase, family 2
A5891_RS17585	COG2363	Small membrane protein
A5891_RS17590	COG2233	PERMEase
A5891_RS17605	COG1216	Glycosyl transferase, family 2
A5891_RS17620	COG1695	Transcriptional regulator
A5891_RS17625	COG0351	phosphomethylpyrimidine kinase
A5891_RS17635	COG1621	beta-fructofuranosidase activity
A5891_RS17640	COG1263	PTS System
A5891_RS17640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5891_RS17645	COG3711	transcriptional antiterminator
A5891_RS17655	COG1404	Belongs to the peptidase S8 family
A5891_RS17660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A5891_RS17665	COG0778	Nitroreductase
A5891_RS17670	COG0772	Belongs to the SEDS family
A5891_RS17675	COG0454	-acetyltransferase
A5891_RS17695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A5891_RS17700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A5891_RS17705	COG2261	transglycosylase associated protein
A5891_RS17710	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A5891_RS17715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A5891_RS17720	COG2246	polysaccharide biosynthetic process
A5891_RS17725	COG1309	transcriptional regulator
A5891_RS17745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A5891_RS17750	COG2837	iron assimilation
A5891_RS17765	COG0583	DNA-binding transcription factor activity
A5891_RS17775	COG1346	cytolysis
A5891_RS17780	COG4895	conserved protein (DUF2196)
A5891_RS17785	COG0789	Transcriptional regulator
A5891_RS17790	COG5504	Zn-dependent protease
A5891_RS17795	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A5891_RS17800	COG0346	lactoylglutathione lyase activity
A5891_RS17805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A5891_RS17810	COG1404	Belongs to the peptidase S8 family
A5891_RS17815	COG1442	glycosyl transferase family 8
A5891_RS17820	COG2357	RelA SpoT domain protein
A5891_RS17825	COG1575	Belongs to the MenA family. Type 1 subfamily
A5891_RS17840	COG1696	Membrane protein involved in D-alanine export
A5891_RS17850	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A5891_RS17855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A5891_RS17860	COG1486	melibiose metabolic process
A5891_RS17865	COG1447	Phosphotransferase system cellobiose-specific component IIA
A5891_RS17870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A5891_RS17875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A5891_RS17880	COG3711	transcriptional antiterminator
A5891_RS17880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5891_RS17890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5891_RS17895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5891_RS17905	COG0640	Transcriptional regulator
A5891_RS17910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A5891_RS17915	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A5891_RS17920	COG1447	Phosphotransferase system cellobiose-specific component IIA
A5891_RS17925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A5891_RS17930	COG2723	6-phospho-beta-galactosidase activity
A5891_RS17940	COG1482	cell wall glycoprotein biosynthetic process
A5891_RS17950	COG0753	catalase activity
A5891_RS17955	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A5891_RS17960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A5891_RS17980	COG3279	Response regulator of the LytR AlgR family
A5891_RS18000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A5891_RS18005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A5891_RS18010	COG4988	ABC transporter
A5891_RS18015	COG1294	oxidase, subunit
A5891_RS18020	COG1271	oxidase subunit
A5891_RS18025	COG3493	citrate carrier protein
A5891_RS18030	COG0726	polysaccharide deacetylase
A5891_RS18035	COG3842	ATPase activity
A5891_RS18040	COG2508	Transcriptional regulator
A5891_RS18045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A5891_RS18055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A5891_RS18065	COG4894	glucomannan catabolic process
A5891_RS18070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A5891_RS18075	COG0500	methyltransferase
A5891_RS18080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A5891_RS18095	COG0693	protein deglycase activity
A5891_RS18095	COG0753	catalase activity
A5891_RS18100	COG2851	Citrate transporter
A5891_RS18105	COG2273	Hydrolase Family 16
A5891_RS18110	COG2270	Major facilitator Superfamily
A5891_RS18115	COG0513	Belongs to the DEAD box helicase family
A5891_RS18125	COG0697	spore germination
A5891_RS18130	COG0589	response to stress
A5891_RS18135	COG2723	6-phospho-beta-galactosidase activity
A5891_RS18185	COG3507	Belongs to the glycosyl hydrolase 43 family
A5891_RS18215	COG0010	Belongs to the arginase family
A5891_RS18220	COG0833	amino acid
A5891_RS18225	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A5891_RS18230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A5891_RS18240	COG2390	Transcriptional regulator
A5891_RS18245	COG0561	phosphatase activity
A5891_RS18275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A5891_RS18280	COG5294	Protein conserved in bacteria
A5891_RS18285	COG0577	efflux transmembrane transporter activity
A5891_RS18290	COG1136	(ABC) transporter
A5891_RS18295	COG2205	protein histidine kinase activity
A5891_RS18300	COG0745	RESPONSE REGULATOR receiver
A5891_RS18305	COG2205	protein histidine kinase activity
A5891_RS18310	COG0745	RESPONSE REGULATOR receiver
A5891_RS18340	COG1082	Xylose isomerase domain protein TIM barrel
A5891_RS18350	COG2814	Major facilitator Superfamily
A5891_RS18380	COG1349	DNA-binding transcription factor activity
A5891_RS18385	COG0667	Aldo Keto reductase
A5891_RS18390	COG2814	Major facilitator Superfamily
A5891_RS18405	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS18410	COG2197	response regulator
A5891_RS18415	COG4585	Histidine kinase
A5891_RS18420	COG3239	Fatty acid desaturase
A5891_RS18425	COG1309	transcriptional regulator
A5891_RS18430	COG1012	belongs to the aldehyde dehydrogenase family
A5891_RS18435	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A5891_RS18445	COG0640	Transcriptional regulator
A5891_RS18450	COG2814	Major facilitator Superfamily
A5891_RS18455	COG1714	RDD family
A5891_RS18465	COG0450	alkyl hydroperoxide reductase
A5891_RS18470	COG3634	alkyl hydroperoxide reductase activity
A5891_RS18475	COG3177	Filamentation induced by cAMP protein fic
A5891_RS18480	COG1113	amino acid transport
A5891_RS18490	COG2080	2 iron, 2 sulfur cluster binding
A5891_RS18505	COG2068	MobA-Related Protein
A5891_RS18510	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A5891_RS18565	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
A5891_RS18570	COG0667	Aldo Keto reductase
A5891_RS18575	COG0456	acetyltransferase
A5891_RS18580	COG0457	Tetratricopeptide repeat
A5891_RS18585	COG0010	Belongs to the arginase family
A5891_RS18590	COG0833	amino acid
A5891_RS18595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A5891_RS18600	COG5658	integral membrane protein
A5891_RS18605	COG0640	Transcriptional regulator
A5891_RS18610	COG3829	transcription factor binding
A5891_RS18620	COG0488	(ABC) transporter
A5891_RS18635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A5891_RS18640	COG5002	protein histidine kinase activity
A5891_RS18640	COG3850	Histidine kinase
A5891_RS18645	COG0745	RESPONSE REGULATOR receiver
A5891_RS18650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A5891_RS18655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A5891_RS18660	COG4853	Protein conserved in bacteria
A5891_RS18665	COG4863	YycH protein
A5891_RS18670	COG5002	protein histidine kinase activity
A5891_RS18675	COG0745	RESPONSE REGULATOR receiver
A5891_RS18710	COG0346	lactoylglutathione lyase activity
A5891_RS18715	COG0305	Participates in initiation and elongation during chromosome replication
A5891_RS18730	COG3093	addiction module antidote protein HigA
A5891_RS18735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A5891_RS18740	COG0297	glycogen (starch) synthase activity
A5891_RS18750	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A5891_RS18755	COG0438	transferase activity, transferring glycosyl groups
A5891_RS18775	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A5891_RS18780	COG4241	membrane
A5891_RS18785	COG5577	PFAM Coat F domain
A5891_RS18790	COG1733	regulation of RNA biosynthetic process
A5891_RS18800	COG0697	spore germination
A5891_RS18805	COG1621	beta-fructofuranosidase activity
A5891_RS18810	COG1621	beta-fructofuranosidase activity
A5891_RS18820	COG2318	DinB family
A5891_RS18825	COG2211	Major facilitator Superfamily
A5891_RS18835	COG0778	Nitroreductase
A5891_RS18840	COG1846	Transcriptional regulator
A5891_RS18845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A5891_RS18850	COG1846	Transcriptional regulator
A5891_RS18855	COG2153	protein acetylation
A5891_RS18865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A5891_RS18870	COG0583	DNA-binding transcription factor activity
A5891_RS18875	COG1028	Short-chain dehydrogenase reductase Sdr
A5891_RS18880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A5891_RS18885	COG0697	spore germination
A5891_RS18910	COG1331	Highly conserved protein containing a thioredoxin domain
A5891_RS18915	COG1266	CAAX protease self-immunity
A5891_RS18920	COG0477	Major facilitator Superfamily
A5891_RS18920	COG2814	Major facilitator Superfamily
A5891_RS18925	COG0346	lactoylglutathione lyase activity
A5891_RS18930	COG1609	Transcriptional regulator
A5891_RS18935	COG0708	Exodeoxyribonuclease III
A5891_RS18940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A5891_RS18945	COG2169	Transcriptional regulator
A5891_RS18955	COG0629	single-stranded DNA binding
A5891_RS18965	COG0012	GTP binding
A5891_RS18970	COG0243	molybdopterin cofactor binding
A5891_RS18975	COG4481	Protein conserved in bacteria
A5891_RS18980	COG3949	Membrane
A5891_RS18995	COG1475	DNA binding
A5891_RS19000	COG1192	Involved in chromosome partitioning
A5891_RS19025	COG1847	R3H domain protein
A5891_RS19030	COG0706	membrane insertase activity