locus-tag	class	description
BVELS4_RS00010	COG0592	DNA-directed DNA polymerase activity
BVELS4_RS00015	COG2501	S4 domain
BVELS4_RS00030	COG0187	DNA topoisomerase II activity
BVELS4_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BVELS4_RS00070	COG0516	GMP reductase activity
BVELS4_RS00070	COG0517	IMP dehydrogenase activity
BVELS4_RS00075	COG1686	Belongs to the peptidase S11 family
BVELS4_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
BVELS4_RS00105	COG1428	Deoxynucleoside kinase
BVELS4_RS00110	COG1428	Deoxynucleoside kinase
BVELS4_RS00115	COG1388	LysM domain
BVELS4_RS00115	COG3858	chitin binding
BVELS4_RS00120	COG1335	isochorismatase
BVELS4_RS00125	COG0590	tRNA wobble adenosine to inosine editing
BVELS4_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVELS4_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BVELS4_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BVELS4_RS00195	COG3853	Toxic anion resistance protein (TelA)
BVELS4_RS00200	COG1982	Orn Lys Arg decarboxylase major
BVELS4_RS00210	COG3870	Protein conserved in bacteria
BVELS4_RS00215	COG1728	Protein conserved in bacteria
BVELS4_RS00220	COG0470	DNA polymerase III
BVELS4_RS00225	COG1774	PSP1 C-terminal conserved region
BVELS4_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BVELS4_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BVELS4_RS00250	COG2002	toxin-antitoxin pair type II binding
BVELS4_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVELS4_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVELS4_RS00260	COG0084	hydrolase, TatD family'
BVELS4_RS00265	COG3583	domain protein
BVELS4_RS00265	COG3584	3D domain protein
BVELS4_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BVELS4_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BVELS4_RS00285	COG4466	Protein conserved in bacteria
BVELS4_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVELS4_RS00305	COG0251	oxidation-reduction process
BVELS4_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVELS4_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVELS4_RS00345	COG2002	toxin-antitoxin pair type II binding
BVELS4_RS00350	COG2244	polysaccharide biosynthetic process
BVELS4_RS00355	COG3956	TIGRFAM MazG family protein
BVELS4_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BVELS4_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BVELS4_RS00380	COG1098	S1 RNA binding domain
BVELS4_RS00395	COG2208	phosphoserine phosphatase activity
BVELS4_RS00400	COG2304	oxidoreductase activity
BVELS4_RS00405	COG0515	serine threonine protein kinase
BVELS4_RS00410	COG0037	tRNA processing
BVELS4_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVELS4_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVELS4_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVELS4_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BVELS4_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
BVELS4_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVELS4_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BVELS4_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVELS4_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BVELS4_RS00475	COG1396	sequence-specific DNA binding
BVELS4_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVELS4_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BVELS4_RS00565	COG4463	regulation of RNA biosynthetic process
BVELS4_RS00570	COG3880	PFAM UvrB UvrC protein
BVELS4_RS00580	COG0542	response to heat
BVELS4_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BVELS4_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BVELS4_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
BVELS4_RS00615	COG1045	serine acetyltransferase
BVELS4_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BVELS4_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVELS4_RS00635	COG3688	RNA-binding protein containing a PIN domain
BVELS4_RS00640	COG1595	DNA-templated transcription, initiation
BVELS4_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BVELS4_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
BVELS4_RS00680	COG2813	Specifically methylates the guanine in position
BVELS4_RS00695	COG1358	cellular component organization or biogenesis
BVELS4_RS00720	COG0596	Alpha beta hydrolase
BVELS4_RS00830	COG0201	protein transport
BVELS4_RS00840	COG0024	Methionine aminopeptidase
BVELS4_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BVELS4_RS00875	COG1122	ATPase activity
BVELS4_RS00880	COG1122	ATPase activity
BVELS4_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BVELS4_RS00905	COG2226	methyltransferase
BVELS4_RS00910	COG2318	DinB family
BVELS4_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS00925	COG0489	protein tyrosine kinase activity
BVELS4_RS00935	COG2194	sulfuric ester hydrolase activity
BVELS4_RS00940	COG0726	polysaccharide deacetylase
BVELS4_RS01000	COG0738	Major facilitator superfamily
BVELS4_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVELS4_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
BVELS4_RS01025	COG0385	Bile acid
BVELS4_RS01030	COG2819	hydrolase of the alpha beta superfamily
BVELS4_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVELS4_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVELS4_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVELS4_RS01050	COG2207	Transcriptional regulator
BVELS4_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVELS4_RS01055	COG3876	Protein conserved in bacteria
BVELS4_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
BVELS4_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVELS4_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVELS4_RS01070	COG1263	PTS System
BVELS4_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVELS4_RS01085	COG1683	Conserved Protein
BVELS4_RS01115	COG1595	DNA-templated transcription, initiation
BVELS4_RS01120	COG5662	AntiSigma factor
BVELS4_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BVELS4_RS01130	COG4856	YbbR-like protein
BVELS4_RS01145	COG1131	(ABC) transporter
BVELS4_RS01170	COG1346	cytolysis
BVELS4_RS01175	COG1380	Effector of murein hydrolase LrgA
BVELS4_RS01180	COG1846	Transcriptional regulator
BVELS4_RS01185	COG1113	amino acid transport
BVELS4_RS01190	COG1011	Hydrolase
BVELS4_RS01195	COG4585	Histidine kinase
BVELS4_RS01200	COG2197	response regulator
BVELS4_RS01205	COG1131	(ABC) transporter
BVELS4_RS01245	COG0531	amino acid
BVELS4_RS01250	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BVELS4_RS01265	COG0584	glycerophosphoryl diester phosphodiesterase
BVELS4_RS01270	COG2271	Major facilitator Superfamily
BVELS4_RS01280	COG2368	4-hydroxyphenylacetate
BVELS4_RS01290	COG3409	Peptidoglycan-binding domain 1 protein
BVELS4_RS01305	COG0371	Dehydrogenase
BVELS4_RS01315	COG1183	phosphatidylcholine synthase activity
BVELS4_RS01320	COG0586	Pfam SNARE associated Golgi protein
BVELS4_RS01325	COG0688	phosphatidylethanolamine metabolic process
BVELS4_RS01340	COG1301	dicarboxylic acid transport
BVELS4_RS01345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVELS4_RS01350	COG0833	amino acid
BVELS4_RS01355	COG2040	homocysteine
BVELS4_RS01360	COG1115	amino acid carrier protein
BVELS4_RS01365	COG2066	Belongs to the glutaminase family
BVELS4_RS01370	COG4191	Histidine kinase
BVELS4_RS01375	COG0784	Response regulator, receiver
BVELS4_RS01395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVELS4_RS01400	COG0778	Nitroreductase
BVELS4_RS01405	COG0346	lactoylglutathione lyase activity
BVELS4_RS01410	COG2259	Doxx family
BVELS4_RS01415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVELS4_RS01425	COG3773	Cell wall hydrolase
BVELS4_RS01430	COG3540	Alkaline phosphatase
BVELS4_RS01435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVELS4_RS01440	COG0805	protein transport
BVELS4_RS01450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVELS4_RS01455	COG0477	Major facilitator Superfamily
BVELS4_RS01460	COG1309	transcriptional regulator
BVELS4_RS01465	COG0252	asparaginase activity
BVELS4_RS01470	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BVELS4_RS01475	COG3012	SEC-C Motif Domain Protein
BVELS4_RS01475	COG1405	negative regulation of cell septum assembly
BVELS4_RS01480	COG0667	Aldo Keto reductase
BVELS4_RS01490	COG1595	DNA-templated transcription, initiation
BVELS4_RS01495	COG1595	DNA-templated transcription, initiation
BVELS4_RS01500	COG1876	peptidase activity
BVELS4_RS01505	COG0457	Tetratricopeptide repeat
BVELS4_RS01510	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS01515	COG0366	Alpha amylase catalytic
BVELS4_RS01520	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVELS4_RS01525	COG1121	(ABC) transporter
BVELS4_RS01530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVELS4_RS01535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVELS4_RS01540	COG2310	stress, protein
BVELS4_RS01545	COG2310	stress, protein
BVELS4_RS01550	COG2310	stress, protein
BVELS4_RS01555	COG0861	Integral membrane protein TerC family
BVELS4_RS01565	COG3853	Toxic anion resistance protein (TelA)
BVELS4_RS01570	COG0477	Major facilitator Superfamily
BVELS4_RS01575	COG0517	IMP dehydrogenase activity
BVELS4_RS01575	COG4175	Glycine betaine
BVELS4_RS01580	COG4176	ABC-type proline glycine betaine transport system permease component
BVELS4_RS01585	COG2113	Glycine betaine
BVELS4_RS01590	COG1473	amidohydrolase
BVELS4_RS01595	COG1288	antiporter activity
BVELS4_RS01605	COG0366	Alpha amylase catalytic
BVELS4_RS01615	COG2814	Major facilitator Superfamily
BVELS4_RS01620	COG1846	Transcriptional regulator
BVELS4_RS01625	COG1280	lysine exporter protein (LysE YggA)
BVELS4_RS01630	COG3403	YqcI/YcgG family
BVELS4_RS01635	COG1113	amino acid transport
BVELS4_RS01640	COG3665	Urea carboxylase-associated protein
BVELS4_RS01655	COG1660	Displays ATPase and GTPase activities
BVELS4_RS01660	COG1082	Xylose isomerase domain protein TIM barrel
BVELS4_RS01665	COG2271	Major facilitator Superfamily
BVELS4_RS01670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BVELS4_RS01675	COG3458	cephalosporin-C deacetylase activity
BVELS4_RS01680	COG3541	Predicted nucleotidyltransferase
BVELS4_RS01685	COG0506	proline dehydrogenase activity
BVELS4_RS01690	COG1012	belongs to the aldehyde dehydrogenase family
BVELS4_RS01695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVELS4_RS01700	COG2508	Transcriptional regulator
BVELS4_RS01710	COG1587	Uroporphyrinogen-III synthase
BVELS4_RS01710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVELS4_RS01715	COG2146	nitrite reductase [NAD(P)H] activity
BVELS4_RS01720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVELS4_RS01725	COG0243	molybdopterin cofactor binding
BVELS4_RS01730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVELS4_RS01735	COG2223	nitrite transmembrane transporter activity
BVELS4_RS01740	COG0523	cobalamin synthesis protein
BVELS4_RS01745	COG1063	alcohol dehydrogenase
BVELS4_RS01750	COG1714	RDD family
BVELS4_RS01760	COG2723	6-phospho-beta-galactosidase activity
BVELS4_RS01770	COG3209	COG3209 Rhs family protein
BVELS4_RS01775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BVELS4_RS01780	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BVELS4_RS01785	COG1733	regulation of RNA biosynthetic process
BVELS4_RS01790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS01805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BVELS4_RS01820	COG0697	spore germination
BVELS4_RS01825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVELS4_RS01835	COG2364	Membrane
BVELS4_RS01840	COG1126	abc transporter atp-binding protein
BVELS4_RS01845	COG0765	amino acid transport
BVELS4_RS01850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVELS4_RS01855	COG0583	DNA-binding transcription factor activity
BVELS4_RS01860	COG0163	prenyltransferase activity
BVELS4_RS01865	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BVELS4_RS01880	COG3104	oligopeptide transport
BVELS4_RS01885	COG5434	Belongs to the glycosyl hydrolase 28 family
BVELS4_RS01895	COG0697	spore germination
BVELS4_RS01905	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BVELS4_RS01910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVELS4_RS01915	COG0456	acetyltransferase
BVELS4_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVELS4_RS01925	COG0765	amino acid transport
BVELS4_RS01930	COG1126	abc transporter atp-binding protein
BVELS4_RS01935	COG1473	amidohydrolase
BVELS4_RS01940	COG2079	MmgE PrpD family protein
BVELS4_RS01945	COG1136	(ABC) transporter
BVELS4_RS01950	COG0577	efflux transmembrane transporter activity
BVELS4_RS01955	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS01960	COG3850	Histidine kinase
BVELS4_RS01960	COG5002	protein histidine kinase activity
BVELS4_RS01965	COG0457	Tetratricopeptide repeat
BVELS4_RS01980	COG0527	aspartate kinase activity
BVELS4_RS01985	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVELS4_RS01990	COG4605	iron ion homeostasis
BVELS4_RS01995	COG4604	ABC transporter, ATP-binding protein
BVELS4_RS02000	COG4607	ABC-type enterochelin transport system periplasmic component
BVELS4_RS02005	COG2814	Major facilitator Superfamily
BVELS4_RS02010	COG1309	transcriptional regulator
BVELS4_RS02015	COG0778	Nitroreductase
BVELS4_RS02020	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BVELS4_RS02025	COG0640	Transcriptional regulator
BVELS4_RS02030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVELS4_RS02035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVELS4_RS02040	COG1012	belongs to the aldehyde dehydrogenase family
BVELS4_RS02045	COG4975	Glucose uptake
BVELS4_RS02050	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS02055	COG4549	nuclear export factor GLE1
BVELS4_RS02060	COG1276	copper resistance
BVELS4_RS02060	COG2372	response to copper ion
BVELS4_RS02065	COG1349	DNA-binding transcription factor activity
BVELS4_RS02075	COG2213	PTS system mannitol-specific
BVELS4_RS02080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVELS4_RS02090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVELS4_RS02100	COG0561	phosphatase activity
BVELS4_RS02110	COG1914	H( )-stimulated, divalent metal cation uptake system
BVELS4_RS02120	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BVELS4_RS02125	COG1984	allophanate hydrolase subunit 2
BVELS4_RS02130	COG1414	Transcriptional regulator
BVELS4_RS02135	COG2755	lipolytic protein G-D-S-L family
BVELS4_RS02145	COG2329	Antibiotic biosynthesis monooxygenase
BVELS4_RS02150	COG0768	penicillin binding
BVELS4_RS02155	COG4989	oxidoreductase activity
BVELS4_RS02160	COG3711	transcriptional antiterminator
BVELS4_RS02165	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS02175	COG1917	Cupin 2, conserved barrel domain protein
BVELS4_RS02180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVELS4_RS02185	COG3871	stress protein (general stress protein 26)
BVELS4_RS02195	COG2814	Major facilitator Superfamily
BVELS4_RS02200	COG1522	sequence-specific DNA binding
BVELS4_RS02205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVELS4_RS02205	COG0551	DNA topoisomerase type I activity
BVELS4_RS02210	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BVELS4_RS02215	COG3706	GGDEF domain
BVELS4_RS02220	COG5298	Protein conserved in bacteria
BVELS4_RS02225	COG1215	transferase activity, transferring glycosyl groups
BVELS4_RS02235	COG0531	amino acid
BVELS4_RS02240	COG0494	nUDIX hydrolase
BVELS4_RS02245	COG0028	Belongs to the TPP enzyme family
BVELS4_RS02270	COG1914	H( )-stimulated, divalent metal cation uptake system
BVELS4_RS02280	COG4876	unkown
BVELS4_RS02290	COG2076	Multidrug Resistance protein
BVELS4_RS02295	COG2217	Heavy metal translocating P-type atpase
BVELS4_RS02300	COG3729	General stress protein
BVELS4_RS02305	COG0662	Cupin 2, conserved barrel domain protein
BVELS4_RS02310	COG2329	Antibiotic biosynthesis monooxygenase
BVELS4_RS02315	COG3546	catalase activity
BVELS4_RS02320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BVELS4_RS02325	COG3290	protein histidine kinase activity
BVELS4_RS02330	COG4565	transcriptional regulatory protein
BVELS4_RS02335	COG1301	dicarboxylic acid transport
BVELS4_RS02340	COG0628	permease
BVELS4_RS02345	COG1131	(ABC) transporter
BVELS4_RS02350	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BVELS4_RS02360	COG1960	acyl-CoA dehydrogenase activity
BVELS4_RS02375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVELS4_RS02380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVELS4_RS02390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVELS4_RS02395	COG0513	Belongs to the DEAD box helicase family
BVELS4_RS02400	COG3402	PFAM membrane-flanked domain
BVELS4_RS02405	COG3428	Bacterial PH domain
BVELS4_RS02410	COG0705	Rhomboid family
BVELS4_RS02420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BVELS4_RS02425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVELS4_RS02430	COG0864	Transcriptional regulator
BVELS4_RS02435	COG2337	Toxic component of a toxin-antitoxin (TA) module
BVELS4_RS02440	COG1366	Belongs to the anti-sigma-factor antagonist family
BVELS4_RS02445	COG1366	Belongs to the anti-sigma-factor antagonist family
BVELS4_RS02450	COG2172	sigma factor antagonist activity
BVELS4_RS02455	COG2208	phosphoserine phosphatase activity
BVELS4_RS02460	COG1366	Belongs to the anti-sigma-factor antagonist family
BVELS4_RS02470	COG1191	sigma factor activity
BVELS4_RS02475	COG2208	phosphoserine phosphatase activity
BVELS4_RS02480	COG2183	response to ionizing radiation
BVELS4_RS02530	COG0582	viral genome integration into host DNA
BVELS4_RS02535	COG2856	Zn peptidase
BVELS4_RS02540	COG1396	sequence-specific DNA binding
BVELS4_RS02570	COG1674	ftsk spoiiie
BVELS4_RS02575	COG2946	Replication initiation factor
BVELS4_RS02620	COG0433	COG0433 Predicted ATPase
BVELS4_RS02630	COG5644	endopeptidase inhibitor activity
BVELS4_RS02635	COG0791	NLP P60 protein
BVELS4_RS02635	COG0741	lytic transglycosylase activity
BVELS4_RS02655	COG0457	Tetratricopeptide repeat
BVELS4_RS02670	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BVELS4_RS02675	COG2076	Multidrug Resistance protein
BVELS4_RS02680	COG2076	Multidrug Resistance protein
BVELS4_RS02685	COG4978	Transcriptional regulator
BVELS4_RS02685	COG0789	Transcriptional regulator
BVELS4_RS02750	COG5444	nuclease activity
BVELS4_RS02755	COG0425	Belongs to the sulfur carrier protein TusA family
BVELS4_RS02755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVELS4_RS02765	COG0477	Major facilitator Superfamily
BVELS4_RS02775	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVELS4_RS02785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVELS4_RS02790	COG0477	Major facilitator Superfamily
BVELS4_RS02795	COG1846	Transcriptional regulator
BVELS4_RS02805	COG2030	dehydratase
BVELS4_RS02820	COG1959	2 iron, 2 sulfur cluster binding
BVELS4_RS02825	COG2910	NAD(P)H-binding
BVELS4_RS02830	COG1309	transcriptional regulator
BVELS4_RS02835	COG0300	oxidoreductase activity
BVELS4_RS02845	COG0604	alcohol dehydrogenase
BVELS4_RS02855	COG3239	Fatty acid desaturase
BVELS4_RS02865	COG1278	Cold shock
BVELS4_RS02870	COG1329	Transcriptional regulator
BVELS4_RS02875	COG1937	Protein conserved in bacteria
BVELS4_RS02880	COG2210	Belongs to the sulfur carrier protein TusA family
BVELS4_RS02890	COG0425	Belongs to the sulfur carrier protein TusA family
BVELS4_RS02890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVELS4_RS02895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVELS4_RS02895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVELS4_RS02900	COG0425	Belongs to the sulfur carrier protein TusA family
BVELS4_RS02905	COG0730	response to heat
BVELS4_RS02910	COG1794	racemase activity, acting on amino acids and derivatives
BVELS4_RS02925	COG3621	Patatin-like phospholipase
BVELS4_RS02935	COG0662	Cupin 2, conserved barrel domain protein
BVELS4_RS02950	COG0277	FAD linked oxidase domain protein
BVELS4_RS02975	COG0662	Cupin 2, conserved barrel domain protein
BVELS4_RS02980	COG2318	DinB family
BVELS4_RS02985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVELS4_RS03010	COG1064	alcohol dehydrogenase
BVELS4_RS03015	COG0789	Transcriptional regulator
BVELS4_RS03025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVELS4_RS03060	COG2814	Major facilitator Superfamily
BVELS4_RS03065	COG1309	transcriptional regulator
BVELS4_RS03070	COG0697	spore germination
BVELS4_RS03075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVELS4_RS03080	COG5577	PFAM Coat F domain
BVELS4_RS03090	COG1063	alcohol dehydrogenase
BVELS4_RS03095	COG5577	PFAM Coat F domain
BVELS4_RS03105	COG0738	Major facilitator superfamily
BVELS4_RS03115	COG0110	maltose O-acetyltransferase activity
BVELS4_RS03120	COG4585	Histidine kinase
BVELS4_RS03125	COG2197	response regulator
BVELS4_RS03130	COG2409	Drug exporters of the RND superfamily
BVELS4_RS03135	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVELS4_RS03140	COG0477	Major facilitator Superfamily
BVELS4_RS03145	COG1959	2 iron, 2 sulfur cluster binding
BVELS4_RS03155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVELS4_RS03160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVELS4_RS03170	COG2814	Major facilitator Superfamily
BVELS4_RS03175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVELS4_RS03185	COG0730	response to heat
BVELS4_RS03190	COG0456	acetyltransferase
BVELS4_RS03195	COG0789	Transcriptional regulator
BVELS4_RS03195	COG4978	Transcriptional regulator
BVELS4_RS03200	COG0697	spore germination
BVELS4_RS03205	COG1051	belongs to the nudix hydrolase family
BVELS4_RS03210	COG2226	methyltransferase
BVELS4_RS03215	COG0473	3-isopropylmalate dehydrogenase activity
BVELS4_RS03220	COG1802	Transcriptional regulator
BVELS4_RS03225	COG1819	glycosyl
BVELS4_RS03240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVELS4_RS03250	COG1388	LysM domain
BVELS4_RS03255	COG2814	Major facilitator Superfamily
BVELS4_RS03260	COG2188	Transcriptional regulator
BVELS4_RS03265	COG2186	Transcriptional regulator
BVELS4_RS03270	COG2807	transmembrane transport
BVELS4_RS03275	COG2076	Multidrug Resistance protein
BVELS4_RS03280	COG2076	Multidrug Resistance protein
BVELS4_RS03285	COG1309	transcriptional regulator
BVELS4_RS03290	COG0531	amino acid
BVELS4_RS03300	COG3832	glyoxalase III activity
BVELS4_RS03305	COG0604	alcohol dehydrogenase
BVELS4_RS03310	COG2814	Major facilitator Superfamily
BVELS4_RS03350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BVELS4_RS03355	COG0802	atpase or kinase
BVELS4_RS03360	COG1214	PFAM Peptidase M22, glycoprotease
BVELS4_RS03365	COG0456	acetyltransferase
BVELS4_RS03370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BVELS4_RS03375	COG0488	(ABC) transporter
BVELS4_RS03390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVELS4_RS03395	COG0805	protein transport
BVELS4_RS03405	COG1266	CAAX protease self-immunity
BVELS4_RS03435	COG0457	Tetratricopeptide repeat
BVELS4_RS03440	COG1063	alcohol dehydrogenase
BVELS4_RS03445	COG2211	Major facilitator Superfamily
BVELS4_RS03450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVELS4_RS03460	COG1842	Phage shock protein A
BVELS4_RS03465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVELS4_RS03470	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BVELS4_RS03475	COG4260	virion core protein, lumpy skin disease virus
BVELS4_RS03480	COG2755	lipolytic protein G-D-S-L family
BVELS4_RS03480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BVELS4_RS03490	COG1595	DNA-templated transcription, initiation
BVELS4_RS03495	COG1063	alcohol dehydrogenase
BVELS4_RS03500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BVELS4_RS03505	COG0823	Involved in the tonB-independent uptake of proteins
BVELS4_RS03520	COG2132	Multicopper oxidase
BVELS4_RS03525	COG1113	amino acid transport
BVELS4_RS03530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVELS4_RS03535	COG0714	Associated with various cellular activities
BVELS4_RS03540	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BVELS4_RS03545	COG1305	Transglutaminase-like
BVELS4_RS03565	COG2252	PERMEase
BVELS4_RS03570	COG3064	Membrane
BVELS4_RS03590	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BVELS4_RS03595	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BVELS4_RS03600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BVELS4_RS03605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BVELS4_RS03610	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BVELS4_RS03625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BVELS4_RS03635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVELS4_RS03640	COG0138	bifunctional purine biosynthesis protein purh
BVELS4_RS03645	COG0151	Belongs to the GarS family
BVELS4_RS03655	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BVELS4_RS03665	COG4496	protein, YerC YecD
BVELS4_RS03670	COG0069	glutamate synthase activity
BVELS4_RS03680	COG0210	DNA helicase
BVELS4_RS03690	COG4851	CamS sex pheromone cAM373 precursor
BVELS4_RS03695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVELS4_RS03700	COG1285	pathogenesis
BVELS4_RS03705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVELS4_RS03725	COG1309	transcriptional regulator
BVELS4_RS03730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVELS4_RS03735	COG1597	lipid kinase activity
BVELS4_RS03740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVELS4_RS03745	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BVELS4_RS03755	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BVELS4_RS03775	COG5444	nuclease activity
BVELS4_RS03785	COG5444	nuclease activity
BVELS4_RS03810	COG3546	catalase activity
BVELS4_RS03815	COG0454	-acetyltransferase
BVELS4_RS03825	COG2323	membrane
BVELS4_RS03835	COG2329	Antibiotic biosynthesis monooxygenase
BVELS4_RS03840	COG0346	lactoylglutathione lyase activity
BVELS4_RS03845	COG1366	Belongs to the anti-sigma-factor antagonist family
BVELS4_RS03850	COG5583	Uncharacterized small protein (DUF2292)
BVELS4_RS03855	COG0196	riboflavin kinase activity
BVELS4_RS03860	COG0670	Belongs to the BI1 family
BVELS4_RS03870	COG1846	Transcriptional regulator
BVELS4_RS03875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVELS4_RS03885	COG2124	cytochrome p450
BVELS4_RS03885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BVELS4_RS03900	COG1131	(ABC) transporter
BVELS4_RS03945	COG4106	trans-aconitate 2-methyltransferase activity
BVELS4_RS03950	COG1368	sulfuric ester hydrolase activity
BVELS4_RS03955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVELS4_RS03960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVELS4_RS03965	COG1442	glycosyl transferase family 8
BVELS4_RS03970	COG1216	Glycosyl transferase, family 2
BVELS4_RS03975	COG1442	glycosyl transferase family 8
BVELS4_RS03980	COG2223	nitrite transmembrane transporter activity
BVELS4_RS03985	COG0531	amino acid
BVELS4_RS03990	COG1012	belongs to the aldehyde dehydrogenase family
BVELS4_RS03995	COG0840	transmembrane signaling receptor activity
BVELS4_RS04000	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS04005	COG0457	Tetratricopeptide repeat
BVELS4_RS04005	COG0463	Glycosyl transferase, family 2
BVELS4_RS04010	COG0488	(ABC) transporter
BVELS4_RS04015	COG0789	Transcriptional regulator
BVELS4_RS04020	COG2814	Major facilitator Superfamily
BVELS4_RS04025	COG0488	(ABC) transporter
BVELS4_RS04030	COG0513	Belongs to the DEAD box helicase family
BVELS4_RS04035	COG0456	acetyltransferase
BVELS4_RS04040	COG2130	NADP-dependent
BVELS4_RS04055	COG3866	Pectate lyase
BVELS4_RS04060	COG0471	metal ion transport
BVELS4_RS04080	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS04080	COG2972	Histidine kinase
BVELS4_RS04085	COG3279	Response regulator of the LytR AlgR family
BVELS4_RS04095	COG3764	Sortase (surface protein transpeptidase)
BVELS4_RS04100	COG3290	protein histidine kinase activity
BVELS4_RS04105	COG4565	transcriptional regulatory protein
BVELS4_RS04110	COG3181	Tripartite tricarboxylate transporter family receptor
BVELS4_RS04115	COG2851	Citrate transporter
BVELS4_RS04120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVELS4_RS04125	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BVELS4_RS04135	COG2258	MOSC domain
BVELS4_RS04155	COG0024	Methionine aminopeptidase
BVELS4_RS04160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVELS4_RS04160	COG1263	PTS System
BVELS4_RS04170	COG1368	sulfuric ester hydrolase activity
BVELS4_RS04180	COG0071	Belongs to the small heat shock protein (HSP20) family
BVELS4_RS04195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVELS4_RS04195	COG1263	PTS System
BVELS4_RS04200	COG0366	Alpha amylase catalytic
BVELS4_RS04205	COG2188	Transcriptional regulator
BVELS4_RS04210	COG0778	Nitroreductase
BVELS4_RS04225	COG0737	Belongs to the 5'-nucleotidase family
BVELS4_RS04230	COG0693	protein deglycase activity
BVELS4_RS04235	COG1609	Transcriptional regulator
BVELS4_RS04250	COG2814	Major facilitator Superfamily
BVELS4_RS04260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVELS4_RS04265	COG4980	gas vesicle protein
BVELS4_RS04270	COG1295	ribonuclease BN
BVELS4_RS04275	COG0477	Major facilitator Superfamily
BVELS4_RS04280	COG0387	Pfam Sodium calcium exchanger
BVELS4_RS04290	COG0668	transmembrane transport
BVELS4_RS04295	COG0535	radical SAM domain protein
BVELS4_RS04305	COG0726	polysaccharide deacetylase
BVELS4_RS04310	COG2084	Dehydrogenase
BVELS4_RS04320	COG0598	Magnesium transport protein CorA
BVELS4_RS04325	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BVELS4_RS04330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVELS4_RS04340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVELS4_RS04345	COG4637	Psort location Cytoplasmic, score
BVELS4_RS04350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVELS4_RS04355	COG0022	dehydrogenase e1 component
BVELS4_RS04360	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVELS4_RS04365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVELS4_RS04370	COG3284	Transcriptional regulator
BVELS4_RS04380	COG1486	melibiose metabolic process
BVELS4_RS04385	COG1737	Transcriptional regulator
BVELS4_RS04390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVELS4_RS04390	COG1263	PTS System
BVELS4_RS04395	COG5434	Belongs to the glycosyl hydrolase 28 family
BVELS4_RS04400	COG1132	(ABC) transporter
BVELS4_RS04405	COG1132	(ABC) transporter
BVELS4_RS04410	COG2259	Doxx family
BVELS4_RS04415	COG2514	catechol 2,3-dioxygenase activity
BVELS4_RS04425	COG1695	Transcriptional regulator
BVELS4_RS04430	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVELS4_RS04435	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BVELS4_RS04440	COG3848	Pyruvate phosphate dikinase
BVELS4_RS04440	COG0574	Belongs to the PEP-utilizing enzyme family
BVELS4_RS04445	COG2732	(Barnase) inhibitor
BVELS4_RS04450	COG2318	DinB family
BVELS4_RS04455	COG2814	Major facilitator Superfamily
BVELS4_RS04460	COG1846	Transcriptional regulator
BVELS4_RS04465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BVELS4_RS04465	COG0392	lysyltransferase activity
BVELS4_RS04470	COG0384	phenazine biosynthesis protein PhzF
BVELS4_RS04475	COG0778	Nitroreductase
BVELS4_RS04490	COG1090	epimerase
BVELS4_RS04505	COG2814	Major facilitator Superfamily
BVELS4_RS04515	COG3591	Belongs to the peptidase S1B family
BVELS4_RS04530	COG3103	Sh3 type 3 domain protein
BVELS4_RS04535	COG5658	integral membrane protein
BVELS4_RS04540	COG0596	Alpha beta hydrolase
BVELS4_RS04545	COG0463	Glycosyl transferase, family 2
BVELS4_RS04550	COG4485	Bacterial membrane protein, YfhO
BVELS4_RS04555	COG1988	membrane-bound metal-dependent
BVELS4_RS04560	COG1194	a g-specific adenine glycosylase
BVELS4_RS04570	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS04590	COG1132	(ABC) transporter
BVELS4_RS04595	COG4129	membrane
BVELS4_RS04605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVELS4_RS04610	COG0735	belongs to the Fur family
BVELS4_RS04720	COG1757	Na H antiporter
BVELS4_RS04725	COG3340	Belongs to the peptidase S51 family
BVELS4_RS04735	COG0277	FAD linked oxidase domain protein
BVELS4_RS04745	COG0747	negative chemotaxis
BVELS4_RS04750	COG0601	transmembrane transport
BVELS4_RS04755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVELS4_RS04760	COG0444	Belongs to the ABC transporter superfamily
BVELS4_RS04765	COG4608	Belongs to the ABC transporter superfamily
BVELS4_RS04770	COG0753	catalase activity
BVELS4_RS04780	COG1116	anion transmembrane transporter activity
BVELS4_RS04785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVELS4_RS04790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVELS4_RS04810	COG1476	TRANSCRIPTIONal
BVELS4_RS04820	COG3382	B3 4 domain protein
BVELS4_RS04825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVELS4_RS04835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BVELS4_RS04840	COG0789	Transcriptional regulator
BVELS4_RS04845	COG1664	Polymer-forming cytoskeletal
BVELS4_RS04850	COG1664	Polymer-forming cytoskeletal
BVELS4_RS04855	COG2766	serine protein kinase
BVELS4_RS04865	COG1846	Transcriptional regulator
BVELS4_RS04870	COG1566	PFAM secretion protein HlyD family protein
BVELS4_RS04875	COG2814	Major facilitator Superfamily
BVELS4_RS04880	COG0655	NAD(P)H dehydrogenase (quinone) activity
BVELS4_RS04895	COG1725	Transcriptional regulator
BVELS4_RS04900	COG1131	(ABC) transporter
BVELS4_RS04905	COG1131	(ABC) transporter
BVELS4_RS04910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BVELS4_RS04915	COG1278	Cold shock
BVELS4_RS04925	COG3706	GGDEF domain
BVELS4_RS04930	COG1823	symporter activity
BVELS4_RS04950	COG5577	PFAM Coat F domain
BVELS4_RS04955	COG0737	Belongs to the 5'-nucleotidase family
BVELS4_RS04955	COG4085	toxin activity
BVELS4_RS04955	COG1525	nuclease
BVELS4_RS04960	COG3764	Sortase (surface protein transpeptidase)
BVELS4_RS04965	COG0564	pseudouridine synthase activity
BVELS4_RS04975	COG0517	IMP dehydrogenase activity
BVELS4_RS04980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVELS4_RS04985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVELS4_RS04985	COG3153	acetyltransferase
BVELS4_RS04990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVELS4_RS04995	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BVELS4_RS05000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BVELS4_RS05010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BVELS4_RS05015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVELS4_RS05020	COG4585	Histidine kinase
BVELS4_RS05020	COG2203	Gaf domain
BVELS4_RS05025	COG2197	response regulator
BVELS4_RS05030	COG0431	NADPH-dependent FMN reductase
BVELS4_RS05045	COG0791	NLP P60 protein
BVELS4_RS05045	COG1388	LysM domain
BVELS4_RS05050	COG1959	2 iron, 2 sulfur cluster binding
BVELS4_RS05055	COG0668	transmembrane transport
BVELS4_RS05060	COG2719	SpoVR family
BVELS4_RS05065	COG1785	Belongs to the alkaline phosphatase family
BVELS4_RS05070	COG1388	LysM domain
BVELS4_RS05070	COG0791	NLP P60 protein
BVELS4_RS05075	COG0583	DNA-binding transcription factor activity
BVELS4_RS05080	COG0372	Belongs to the citrate synthase family
BVELS4_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS05090	COG0531	amino acid
BVELS4_RS05095	COG0733	neurotransmitter:sodium symporter activity
BVELS4_RS05110	COG1595	DNA-templated transcription, initiation
BVELS4_RS05115	COG0204	Acyl-transferase
BVELS4_RS05120	COG1253	flavin adenine dinucleotide binding
BVELS4_RS05125	COG0789	Transcriptional regulator
BVELS4_RS05130	COG0436	Aminotransferase
BVELS4_RS05135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVELS4_RS05140	COG1253	flavin adenine dinucleotide binding
BVELS4_RS05145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BVELS4_RS05150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BVELS4_RS05155	COG0584	glycerophosphoryl diester phosphodiesterase
BVELS4_RS05165	COG0668	transmembrane transport
BVELS4_RS05170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BVELS4_RS05175	COG0726	polysaccharide deacetylase
BVELS4_RS05180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVELS4_RS05185	COG3226	Transcriptional regulator
BVELS4_RS05195	COG0589	response to stress
BVELS4_RS05200	COG1132	(ABC) transporter
BVELS4_RS05205	COG1132	(ABC) transporter
BVELS4_RS05210	COG0702	epimerase
BVELS4_RS05225	COG0189	ligase activity
BVELS4_RS05230	COG0189	ligase activity
BVELS4_RS05245	COG4335	DNA alkylation repair
BVELS4_RS05250	COG0561	phosphatase activity
BVELS4_RS05255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVELS4_RS05265	COG0475	glutathione-regulated potassium exporter activity
BVELS4_RS05270	COG0490	domain, Protein
BVELS4_RS05280	COG1024	Enoyl-CoA hydratase
BVELS4_RS05290	COG4152	abc transporter atp-binding protein
BVELS4_RS05295	COG1668	transmembrane transport
BVELS4_RS05300	COG0420	3'-5' exonuclease activity
BVELS4_RS05305	COG4717	serine-type aminopeptidase activity
BVELS4_RS05320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVELS4_RS05355	COG4980	gas vesicle protein
BVELS4_RS05370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BVELS4_RS05375	COG0537	adenosine 5'-monophosphoramidase activity
BVELS4_RS05380	COG1131	(ABC) transporter
BVELS4_RS05385	COG4473	ABC transporter
BVELS4_RS05395	COG1473	amidohydrolase
BVELS4_RS05400	COG3069	C4-dicarboxylate transmembrane transporter activity
BVELS4_RS05405	COG2329	Antibiotic biosynthesis monooxygenase
BVELS4_RS05410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVELS4_RS05430	COG1309	transcriptional regulator
BVELS4_RS05435	COG1511	domain protein
BVELS4_RS05440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVELS4_RS05450	COG1363	Peptidase, m42
BVELS4_RS05455	COG1301	dicarboxylic acid transport
BVELS4_RS05465	COG1234	tRNA 3'-trailer cleavage
BVELS4_RS05470	COG0095	Lipoate-protein ligase
BVELS4_RS05475	COG0702	epimerase
BVELS4_RS05480	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS05490	COG0501	Belongs to the peptidase M48B family
BVELS4_RS05495	COG1404	Belongs to the peptidase S8 family
BVELS4_RS05505	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BVELS4_RS05510	COG0406	alpha-ribazole phosphatase activity
BVELS4_RS05515	COG0183	Belongs to the thiolase family
BVELS4_RS05520	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS05525	COG1268	BioY protein
BVELS4_RS05530	COG0840	transmembrane signaling receptor activity
BVELS4_RS05535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVELS4_RS05535	COG0723	plastoquinol--plastocyanin reductase activity
BVELS4_RS05540	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS05550	COG4903	ComK protein
BVELS4_RS05570	COG5646	InterPro IPR014922
BVELS4_RS05595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVELS4_RS05610	COG0398	Pfam SNARE associated Golgi protein
BVELS4_RS05615	COG0681	Belongs to the peptidase S26 family
BVELS4_RS05620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVELS4_RS05625	COG1846	Transcriptional regulator
BVELS4_RS05630	COG3180	Ammonia monooxygenase
BVELS4_RS05635	COG2814	Major facilitator Superfamily
BVELS4_RS05645	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BVELS4_RS05650	COG2323	membrane
BVELS4_RS05665	COG0420	3'-5' exonuclease activity
BVELS4_RS05670	COG0419	ATPase involved in DNA repair
BVELS4_RS05675	COG1403	HNH endonuclease
BVELS4_RS05715	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVELS4_RS05730	COG0367	asparagine synthase
BVELS4_RS05735	COG1562	ergosterol biosynthetic process
BVELS4_RS05740	COG0534	Mate efflux family protein
BVELS4_RS05745	COG1917	Cupin 2, conserved barrel domain protein
BVELS4_RS05745	COG2207	Transcriptional regulator
BVELS4_RS05750	COG2318	DinB family
BVELS4_RS05760	COG2153	protein acetylation
BVELS4_RS05765	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVELS4_RS05765	COG0646	methionine synthase
BVELS4_RS05775	COG2996	Protein conserved in bacteria
BVELS4_RS05785	COG0840	transmembrane signaling receptor activity
BVELS4_RS05790	COG2124	cytochrome p450
BVELS4_RS05800	COG1307	EDD domain protein, DegV family
BVELS4_RS05805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVELS4_RS05825	COG0561	phosphatase activity
BVELS4_RS05830	COG1073	alpha beta
BVELS4_RS05835	COG2151	metal-sulfur cluster biosynthetic enzyme
BVELS4_RS05845	COG0277	FAD linked oxidase domain protein
BVELS4_RS05850	COG2271	Major facilitator Superfamily
BVELS4_RS05860	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BVELS4_RS05870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVELS4_RS05875	COG0505	Belongs to the CarA family
BVELS4_RS05880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BVELS4_RS05885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BVELS4_RS05900	COG2267	carboxylic ester hydrolase activity
BVELS4_RS05910	COG1744	ABC transporter substrate-binding protein PnrA-like
BVELS4_RS05925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVELS4_RS05930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVELS4_RS05935	COG5504	Zn-dependent protease
BVELS4_RS05940	COG0444	Belongs to the ABC transporter superfamily
BVELS4_RS05945	COG4608	Belongs to the ABC transporter superfamily
BVELS4_RS05955	COG0601	transmembrane transport
BVELS4_RS05960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVELS4_RS05970	COG0180	Tryptophanyl-tRNA synthetase
BVELS4_RS05975	COG4166	transmembrane transport
BVELS4_RS05980	COG0601	transmembrane transport
BVELS4_RS05985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVELS4_RS05990	COG0444	Belongs to the ABC transporter superfamily
BVELS4_RS05995	COG4608	Belongs to the ABC transporter superfamily
BVELS4_RS06005	COG0456	acetyltransferase
BVELS4_RS06010	COG1393	Belongs to the ArsC family
BVELS4_RS06015	COG0861	Integral membrane protein TerC family
BVELS4_RS06020	COG4862	establishment of competence for transformation
BVELS4_RS06025	COG4469	Competence protein
BVELS4_RS06030	COG1164	Oligoendopeptidase f
BVELS4_RS06045	COG2346	COG2346, Truncated hemoglobins
BVELS4_RS06050	COG0741	lytic transglycosylase activity
BVELS4_RS06055	COG4116	CYTH
BVELS4_RS06065	COG2357	RelA SpoT domain protein
BVELS4_RS06070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVELS4_RS06075	COG0564	pseudouridine synthase activity
BVELS4_RS06085	COG0475	glutathione-regulated potassium exporter activity
BVELS4_RS06085	COG0569	domain protein
BVELS4_RS06090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BVELS4_RS06095	COG0352	thiamine-phosphate diphosphorylase activity
BVELS4_RS06100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVELS4_RS06105	COG2104	thiamine diphosphate biosynthetic process
BVELS4_RS06115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVELS4_RS06120	COG0351	phosphomethylpyrimidine kinase
BVELS4_RS06125	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BVELS4_RS06180	COG0210	DNA helicase
BVELS4_RS06200	COG1131	(ABC) transporter
BVELS4_RS06210	COG2153	protein acetylation
BVELS4_RS06225	COG0626	cystathionine gamma-synthase activity
BVELS4_RS06230	COG0626	cystathionine gamma-synthase activity
BVELS4_RS06245	COG5444	nuclease activity
BVELS4_RS06270	COG5444	nuclease activity
BVELS4_RS06280	COG0346	lactoylglutathione lyase activity
BVELS4_RS06285	COG2367	Beta-lactamase
BVELS4_RS06290	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BVELS4_RS06300	COG1846	Transcriptional regulator
BVELS4_RS06310	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BVELS4_RS06315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVELS4_RS06320	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BVELS4_RS06325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVELS4_RS06325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVELS4_RS06330	COG1447	Phosphotransferase system cellobiose-specific component IIA
BVELS4_RS06360	COG1285	pathogenesis
BVELS4_RS06375	COG2205	protein histidine kinase activity
BVELS4_RS06385	COG3383	formate dehydrogenase (NAD+) activity
BVELS4_RS06390	COG2427	Protein of unknown function (DUF1641)
BVELS4_RS06395	COG2124	cytochrome p450
BVELS4_RS06400	COG1819	glycosyl
BVELS4_RS06410	COG1587	Uroporphyrinogen-III synthase
BVELS4_RS06415	COG0390	transport system, permease component
BVELS4_RS06420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVELS4_RS06425	COG0697	spore germination
BVELS4_RS06430	COG4297	protein containing double-stranded beta helix domain
BVELS4_RS06440	COG1252	NADH dehydrogenase
BVELS4_RS06450	COG2211	Major facilitator Superfamily
BVELS4_RS06455	COG1609	Transcriptional regulator
BVELS4_RS06460	COG0246	Mannitol dehydrogenase
BVELS4_RS06465	COG2721	sulfolactate sulfo-lyase activity
BVELS4_RS06470	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS06475	COG2770	Histidine kinase
BVELS4_RS06475	COG2205	protein histidine kinase activity
BVELS4_RS06495	COG0730	response to heat
BVELS4_RS06500	COG2318	DinB family
BVELS4_RS06505	COG0457	Tetratricopeptide repeat
BVELS4_RS06515	COG1388	LysM domain
BVELS4_RS06515	COG3409	Peptidoglycan-binding domain 1 protein
BVELS4_RS06515	COG5632	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS06525	COG4195	phage-related replication protein
BVELS4_RS06530	COG2856	Zn peptidase
BVELS4_RS06535	COG1396	sequence-specific DNA binding
BVELS4_RS06545	COG1522	sequence-specific DNA binding
BVELS4_RS06550	COG1484	DNA-dependent DNA replication
BVELS4_RS06570	COG1595	DNA-templated transcription, initiation
BVELS4_RS06575	COG5484	DNA packaging
BVELS4_RS06575	COG3728	DNA packaging
BVELS4_RS06580	COG1783	phage Terminase large subunit
BVELS4_RS06585	COG5518	Phage portal protein
BVELS4_RS06590	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BVELS4_RS06595	COG4653	Phage capsid family
BVELS4_RS06645	COG5412	phage tail tape measure protein
BVELS4_RS06645	COG3953	SLT domain
BVELS4_RS06645	COG5412	phage tail tape measure protein
BVELS4_RS06645	COG3953	SLT domain
BVELS4_RS06645	COG5412	phage tail tape measure protein
BVELS4_RS06645	COG3953	SLT domain
BVELS4_RS06650	COG1652	LysM domain
BVELS4_RS06655	COG4193	domain, Protein
BVELS4_RS06665	COG3628	GPW Gp25 family protein
BVELS4_RS06670	COG3299	homolog of phage Mu protein gp47
BVELS4_RS06675	COG3778	Protein conserved in bacteria
BVELS4_RS06715	COG3409	Peptidoglycan-binding domain 1 protein
BVELS4_RS06715	COG5632	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS06730	COG0306	phosphate transporter
BVELS4_RS06735	COG1392	Phosphate transport regulator
BVELS4_RS06740	COG0531	amino acid
BVELS4_RS06745	COG0346	lactoylglutathione lyase activity
BVELS4_RS06750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BVELS4_RS06755	COG0463	Glycosyl transferase, family 2
BVELS4_RS06765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVELS4_RS06770	COG0477	Major facilitator Superfamily
BVELS4_RS06775	COG2362	D-Aminopeptidase
BVELS4_RS06780	COG0601	transmembrane transport
BVELS4_RS06785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVELS4_RS06790	COG0444	Belongs to the ABC transporter superfamily
BVELS4_RS06795	COG4166	transmembrane transport
BVELS4_RS06800	COG1619	proteins homologs of microcin C7 resistance protein MccF
BVELS4_RS06805	COG4948	Mandelate Racemase Muconate Lactonizing
BVELS4_RS06810	COG0791	NLP P60 protein
BVELS4_RS06815	COG4608	Belongs to the ABC transporter superfamily
BVELS4_RS06820	COG2706	6-phosphogluconolactonase activity
BVELS4_RS06825	COG1834	amidinotransferase
BVELS4_RS06830	COG1607	acyl-coa hydrolase
BVELS4_RS06835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVELS4_RS06840	COG2076	Multidrug Resistance protein
BVELS4_RS06845	COG2076	Multidrug Resistance protein
BVELS4_RS06850	COG0788	formyltetrahydrofolate deformylase activity
BVELS4_RS06855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BVELS4_RS06865	COG1764	response to oxidative stress
BVELS4_RS06870	COG1846	Transcriptional regulator
BVELS4_RS06875	COG1764	response to oxidative stress
BVELS4_RS06890	COG0457	Tetratricopeptide repeat
BVELS4_RS06890	COG0463	Glycosyl transferase, family 2
BVELS4_RS06900	COG2814	Major facilitator Superfamily
BVELS4_RS06905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVELS4_RS06915	COG1404	Belongs to the peptidase S8 family
BVELS4_RS06920	COG1366	Belongs to the anti-sigma-factor antagonist family
BVELS4_RS06925	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BVELS4_RS06930	COG1122	ATPase activity
BVELS4_RS06935	COG4721	ABC-type cobalt transport system, permease component
BVELS4_RS06940	COG1388	LysM domain
BVELS4_RS06940	COG3858	chitin binding
BVELS4_RS06955	COG2239	Acts as a magnesium transporter
BVELS4_RS06965	COG0789	Transcriptional regulator
BVELS4_RS06980	COG1846	Transcriptional regulator
BVELS4_RS06985	COG0726	polysaccharide deacetylase
BVELS4_RS06990	COG3285	dna ligase
BVELS4_RS06990	COG1793	dna ligase
BVELS4_RS06995	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BVELS4_RS07000	COG0586	Pfam SNARE associated Golgi protein
BVELS4_RS07005	COG0861	Integral membrane protein TerC family
BVELS4_RS07010	COG1191	sigma factor activity
BVELS4_RS07040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVELS4_RS07045	COG2323	membrane
BVELS4_RS07055	COG3594	Acyltransferase
BVELS4_RS07060	COG5002	protein histidine kinase activity
BVELS4_RS07065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVELS4_RS07080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVELS4_RS07085	COG0436	Aminotransferase
BVELS4_RS07115	COG3852	Histidine kinase
BVELS4_RS07120	COG1846	Transcriptional regulator
BVELS4_RS07125	COG1360	Flagellar Motor Protein
BVELS4_RS07130	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVELS4_RS07135	COG0542	response to heat
BVELS4_RS07140	COG3949	Membrane
BVELS4_RS07155	COG0720	synthase
BVELS4_RS07160	COG0602	queuosine metabolic process
BVELS4_RS07175	COG1733	regulation of RNA biosynthetic process
BVELS4_RS07180	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS07190	COG4641	Protein conserved in bacteria
BVELS4_RS07190	COG1388	LysM domain
BVELS4_RS07195	COG1388	LysM domain
BVELS4_RS07200	COG3858	chitin binding
BVELS4_RS07210	COG4873	Protein conserved in bacteria
BVELS4_RS07220	COG3773	Cell wall hydrolase
BVELS4_RS07225	COG2244	polysaccharide biosynthetic process
BVELS4_RS07230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVELS4_RS07235	COG2217	Heavy metal translocating P-type atpase
BVELS4_RS07240	COG0006	proline dipeptidase activity
BVELS4_RS07245	COG1609	Transcriptional regulator
BVELS4_RS07250	COG3711	transcriptional antiterminator
BVELS4_RS07255	COG1263	PTS System
BVELS4_RS07255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVELS4_RS07255	COG2190	(PTS) system
BVELS4_RS07260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVELS4_RS07265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVELS4_RS07275	COG1533	DNA photolyase activity
BVELS4_RS07280	COG0840	transmembrane signaling receptor activity
BVELS4_RS07285	COG2084	Dehydrogenase
BVELS4_RS07295	COG0347	Belongs to the P(II) protein family
BVELS4_RS07300	COG2340	Cysteine-rich secretory protein family
BVELS4_RS07305	COG0768	penicillin binding
BVELS4_RS07310	COG4191	Histidine kinase
BVELS4_RS07315	COG0436	Aminotransferase
BVELS4_RS07325	COG0784	Response regulator, receiver
BVELS4_RS07325	COG0835	chemotaxis
BVELS4_RS07335	COG2814	Major facilitator Superfamily
BVELS4_RS07340	COG1376	ErfK ybiS ycfS ynhG family protein
BVELS4_RS07345	COG1408	metallophosphoesterase
BVELS4_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS07360	COG2200	EAL domain
BVELS4_RS07365	COG4703	Protein of unknown function (DUF1797)
BVELS4_RS07370	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BVELS4_RS07380	COG0517	IMP dehydrogenase activity
BVELS4_RS07385	COG0583	DNA-binding transcription factor activity
BVELS4_RS07390	COG0716	FMN binding
BVELS4_RS07400	COG0716	FMN binding
BVELS4_RS07420	COG0668	transmembrane transport
BVELS4_RS07425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVELS4_RS07445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVELS4_RS07450	COG0303	'Molybdopterin
BVELS4_RS07455	COG1763	Mo-molybdopterin cofactor biosynthetic process
BVELS4_RS07460	COG0314	molybdopterin synthase activity
BVELS4_RS07465	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BVELS4_RS07475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVELS4_RS07480	COG1136	(ABC) transporter
BVELS4_RS07485	COG0577	efflux transmembrane transporter activity
BVELS4_RS07490	COG1349	DNA-binding transcription factor activity
BVELS4_RS07495	COG1105	Belongs to the carbohydrate kinase PfkB family
BVELS4_RS07500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVELS4_RS07500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVELS4_RS07500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVELS4_RS07505	COG0681	Belongs to the peptidase S26 family
BVELS4_RS07515	COG0488	(ABC) transporter
BVELS4_RS07520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVELS4_RS07525	COG2309	aminopeptidase activity
BVELS4_RS07535	COG1077	Cell shape determining protein MreB Mrl
BVELS4_RS07540	COG2002	toxin-antitoxin pair type II binding
BVELS4_RS07545	COG3852	Histidine kinase
BVELS4_RS07550	COG2105	PFAM AIG2 family protein
BVELS4_RS07550	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BVELS4_RS07555	COG0569	domain protein
BVELS4_RS07565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BVELS4_RS07575	COG0561	phosphatase activity
BVELS4_RS07580	COG0242	peptide deformylase activity
BVELS4_RS07590	COG0497	DNA recombination
BVELS4_RS07605	COG3321	synthase
BVELS4_RS07605	COG4221	oxidoreductase activity
BVELS4_RS07605	COG0300	oxidoreductase activity
BVELS4_RS07605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS07610	COG4221	oxidoreductase activity
BVELS4_RS07610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS07610	COG3321	synthase
BVELS4_RS07610	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS07615	COG4221	oxidoreductase activity
BVELS4_RS07615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS07615	COG0300	oxidoreductase activity
BVELS4_RS07615	COG3321	synthase
BVELS4_RS07620	COG0300	oxidoreductase activity
BVELS4_RS07620	COG3321	synthase
BVELS4_RS07620	COG4221	oxidoreductase activity
BVELS4_RS07620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS07625	COG4221	oxidoreductase activity
BVELS4_RS07625	COG3321	synthase
BVELS4_RS07625	COG0300	oxidoreductase activity
BVELS4_RS07625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS07630	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS07630	COG3321	synthase
BVELS4_RS07630	COG4221	oxidoreductase activity
BVELS4_RS07630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS07635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVELS4_RS07640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVELS4_RS07645	COG0022	dehydrogenase e1 component
BVELS4_RS07650	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVELS4_RS07655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVELS4_RS07660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVELS4_RS07675	COG1982	Orn Lys Arg decarboxylase major
BVELS4_RS07695	COG0483	inositol monophosphate 1-phosphatase activity
BVELS4_RS07705	COG3227	Zinc metalloprotease (Elastase)
BVELS4_RS07710	COG1595	DNA-templated transcription, initiation
BVELS4_RS07740	COG4896	Protein conserved in bacteria
BVELS4_RS07750	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BVELS4_RS07755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BVELS4_RS07760	COG2066	Belongs to the glutaminase family
BVELS4_RS07770	COG0772	Belongs to the SEDS family
BVELS4_RS07775	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BVELS4_RS07790	COG2010	Cytochrome c
BVELS4_RS07790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BVELS4_RS07795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BVELS4_RS07800	COG1845	cytochrome c oxidase, subunit III
BVELS4_RS07805	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BVELS4_RS07810	COG3336	cytochrome c oxidase
BVELS4_RS07820	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BVELS4_RS07825	COG2340	Cysteine-rich secretory protein family
BVELS4_RS07840	COG3679	Belongs to the UPF0342 family
BVELS4_RS07850	COG0742	ribosomal rna small subunit methyltransferase
BVELS4_RS07860	COG3314	Sporulation integral membrane protein YlbJ
BVELS4_RS07865	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVELS4_RS07870	COG3480	Lon protease (S16) C-terminal proteolytic domain
BVELS4_RS07880	COG1399	metal-binding, possibly nucleic acid-binding protein
BVELS4_RS07900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVELS4_RS07920	COG4839	cell division protein FtsL
BVELS4_RS07930	COG0768	penicillin binding
BVELS4_RS07950	COG0772	Belongs to the SEDS family
BVELS4_RS07965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BVELS4_RS07970	COG0849	cell division
BVELS4_RS07975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BVELS4_RS07980	COG4412	M6 family metalloprotease domain protein
BVELS4_RS07980	COG1404	Belongs to the peptidase S8 family
BVELS4_RS07990	COG1191	sigma factor activity
BVELS4_RS07995	COG1191	sigma factor activity
BVELS4_RS08000	COG1119	ATPase activity
BVELS4_RS08005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVELS4_RS08010	COG1873	PFAM PRC-barrel domain
BVELS4_RS08020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BVELS4_RS08030	COG0762	integral membrane protein
BVELS4_RS08035	COG2302	S4 RNA-binding domain
BVELS4_RS08040	COG3599	regulation of cell shape
BVELS4_RS08045	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVELS4_RS08050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVELS4_RS08060	COG0564	pseudouridine synthase activity
BVELS4_RS08070	COG2233	PERMEase
BVELS4_RS08080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BVELS4_RS08085	COG0505	Belongs to the CarA family
BVELS4_RS08090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BVELS4_RS08105	COG0284	orotidine-5'-phosphate decarboxylase activity
BVELS4_RS08110	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BVELS4_RS08120	COG0306	phosphate transporter
BVELS4_RS08135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVELS4_RS08140	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BVELS4_RS08145	COG1648	precorrin-2 dehydrogenase activity
BVELS4_RS08155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BVELS4_RS08160	COG1561	YicC-like family, N-terminal region
BVELS4_RS08170	COG0194	GDP metabolic process
BVELS4_RS08180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVELS4_RS08185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVELS4_RS08190	COG0242	peptide deformylase activity
BVELS4_RS08200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVELS4_RS08200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVELS4_RS08210	COG0631	protein serine/threonine phosphatase activity
BVELS4_RS08215	COG0515	serine threonine protein kinase
BVELS4_RS08215	COG2815	serine threonine protein kinase
BVELS4_RS08225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVELS4_RS08230	COG1564	THIamine pyrophosphokinase
BVELS4_RS08245	COG1302	Protein conserved in bacteria
BVELS4_RS08255	COG1760	l-serine dehydratase
BVELS4_RS08260	COG1760	l-serine dehydratase
BVELS4_RS08265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVELS4_RS08280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVELS4_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS08300	COG1196	nuclear chromosome segregation
BVELS4_RS08305	COG0552	protein localization to endoplasmic reticulum
BVELS4_RS08320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVELS4_RS08330	COG1837	Belongs to the UPF0109 family
BVELS4_RS08355	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BVELS4_RS08370	COG2257	FlhB HrpN YscU SpaS Family
BVELS4_RS08380	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BVELS4_RS08385	COG0758	DNA mediated transformation
BVELS4_RS08390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVELS4_RS08400	COG4974	Belongs to the 'phage' integrase family
BVELS4_RS08420	COG1815	bacterial-type flagellum-dependent cell motility
BVELS4_RS08425	COG1558	bacterial-type flagellum-dependent cell motility
BVELS4_RS08430	COG1677	Flagellar hook-basal body complex protein FliE
BVELS4_RS08435	COG1766	The M ring may be actively involved in energy transduction
BVELS4_RS08440	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVELS4_RS08445	COG1317	bacterial-type flagellum organization
BVELS4_RS08450	COG1157	protein secretion by the type III secretion system
BVELS4_RS08455	COG2882	bacterial-type flagellum organization
BVELS4_RS08460	COG3334	PFAM MgtE intracellular
BVELS4_RS08465	COG3144	bacterial-type flagellum assembly
BVELS4_RS08470	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BVELS4_RS08475	COG4786	Flagellar basal body rod
BVELS4_RS08480	COG1582	Flagellar protein (FlbD)
BVELS4_RS08485	COG1580	Controls the rotational direction of flagella during chemotaxis
BVELS4_RS08490	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVELS4_RS08495	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVELS4_RS08495	COG1776	CheC inhibitor of MCP methylation
BVELS4_RS08500	COG2201	protein-glutamate methylesterase activity
BVELS4_RS08505	COG3190	flagellar
BVELS4_RS08510	COG1338	Plays a role in the flagellum-specific transport system
BVELS4_RS08515	COG1987	bacterial-type flagellum assembly
BVELS4_RS08520	COG1684	flagellar biosynthetic protein fliR
BVELS4_RS08525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVELS4_RS08530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVELS4_RS08535	COG1419	protein localization to endoplasmic reticulum
BVELS4_RS08540	COG0455	bacterial-type flagellum organization
BVELS4_RS08545	COG2201	protein-glutamate methylesterase activity
BVELS4_RS08550	COG2198	Histidine kinase
BVELS4_RS08550	COG0643	Histidine kinase
BVELS4_RS08555	COG0835	chemotaxis
BVELS4_RS08560	COG1776	CheC inhibitor of MCP methylation
BVELS4_RS08570	COG1191	sigma factor activity
BVELS4_RS08600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BVELS4_RS08605	COG4589	Belongs to the CDS family
BVELS4_RS08615	COG0750	zinc metalloprotease
BVELS4_RS08625	COG2176	DNA-directed DNA polymerase activity
BVELS4_RS08635	COG0195	Participates in both transcription termination and antitermination
BVELS4_RS08640	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BVELS4_RS08645	COG1358	cellular component organization or biogenesis
BVELS4_RS08655	COG1550	Protein conserved in bacteria
BVELS4_RS08670	COG0196	riboflavin kinase activity
BVELS4_RS08685	COG0726	polysaccharide deacetylase
BVELS4_RS08690	COG0612	Peptidase, M16
BVELS4_RS08695	COG1873	PFAM PRC-barrel domain
BVELS4_RS08700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVELS4_RS08705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVELS4_RS08710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVELS4_RS08715	COG0527	aspartate kinase activity
BVELS4_RS08725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BVELS4_RS08730	COG0740	serine-type endopeptidase activity
BVELS4_RS08740	COG1674	ftsk spoiiie
BVELS4_RS08740	COG4980	gas vesicle protein
BVELS4_RS08745	COG2188	Transcriptional regulator
BVELS4_RS08750	COG2814	Major facilitator Superfamily
BVELS4_RS08755	COG1846	Transcriptional regulator
BVELS4_RS08760	COG1033	growth of symbiont in host cell
BVELS4_RS08760	COG2409	Drug exporters of the RND superfamily
BVELS4_RS08765	COG0612	Peptidase, M16
BVELS4_RS08770	COG0612	Peptidase, M16
BVELS4_RS08775	COG0300	oxidoreductase activity
BVELS4_RS08790	COG1426	Protein conserved in bacteria
BVELS4_RS08795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BVELS4_RS08810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVELS4_RS08820	COG1692	metallophosphoesterase
BVELS4_RS08825	COG2359	stage V sporulation protein S
BVELS4_RS08845	COG4550	Control of competence regulator ComK, YlbF/YmcA
BVELS4_RS08890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS08895	COG3425	synthase
BVELS4_RS08900	COG1024	Enoyl-CoA hydratase
BVELS4_RS08905	COG1024	Enoyl-CoA hydratase
BVELS4_RS08910	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS08910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS08910	COG0300	oxidoreductase activity
BVELS4_RS08910	COG3321	synthase
BVELS4_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS08915	COG4221	oxidoreductase activity
BVELS4_RS08915	COG0300	oxidoreductase activity
BVELS4_RS08915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS08915	COG3321	synthase
BVELS4_RS08920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVELS4_RS08920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS08920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS08920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVELS4_RS08920	COG3321	synthase
BVELS4_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS08920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS08920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS08920	COG3321	synthase
BVELS4_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS08925	COG4221	oxidoreductase activity
BVELS4_RS08925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS08925	COG3321	synthase
BVELS4_RS08930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVELS4_RS08930	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BVELS4_RS08930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS08930	COG3321	synthase
BVELS4_RS08935	COG2124	cytochrome p450
BVELS4_RS08940	COG3209	COG3209 Rhs family protein
BVELS4_RS08945	COG3619	membrane
BVELS4_RS08955	COG1404	Belongs to the peptidase S8 family
BVELS4_RS08965	COG4195	phage-related replication protein
BVELS4_RS08970	COG1764	response to oxidative stress
BVELS4_RS08980	COG2076	Multidrug Resistance protein
BVELS4_RS09020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVELS4_RS09025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVELS4_RS09030	COG4112	unkown
BVELS4_RS09035	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS09045	COG0464	growth
BVELS4_RS09050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVELS4_RS09055	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BVELS4_RS09060	COG0789	Transcriptional regulator
BVELS4_RS09065	COG0174	glutamine synthetase
BVELS4_RS09085	COG2211	Major facilitator Superfamily
BVELS4_RS09090	COG3507	Belongs to the glycosyl hydrolase 43 family
BVELS4_RS09105	COG1070	Carbohydrate kinase
BVELS4_RS09110	COG3848	Pyruvate phosphate dikinase
BVELS4_RS09110	COG0574	Belongs to the PEP-utilizing enzyme family
BVELS4_RS09140	COG1064	alcohol dehydrogenase
BVELS4_RS09165	COG0456	acetyltransferase
BVELS4_RS09195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVELS4_RS09200	COG3397	chitin binding
BVELS4_RS09210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVELS4_RS09225	COG5434	Belongs to the glycosyl hydrolase 28 family
BVELS4_RS09230	COG0756	dUTP diphosphatase activity
BVELS4_RS09235	COG4195	phage-related replication protein
BVELS4_RS09270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BVELS4_RS09280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVELS4_RS09300	COG0785	Cytochrome C biogenesis protein
BVELS4_RS09305	COG2201	protein-glutamate methylesterase activity
BVELS4_RS09310	COG4846	Membrane protein involved in cytochrome C biogenesis
BVELS4_RS09320	COG0071	Belongs to the small heat shock protein (HSP20) family
BVELS4_RS09335	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BVELS4_RS09340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVELS4_RS09360	COG0824	Thioesterase
BVELS4_RS09370	COG4841	protein insertion into membrane
BVELS4_RS09380	COG1832	CoA-binding protein
BVELS4_RS09385	COG0187	DNA topoisomerase II activity
BVELS4_RS09390	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BVELS4_RS09400	COG1115	amino acid carrier protein
BVELS4_RS09410	COG1063	alcohol dehydrogenase
BVELS4_RS09415	COG0800	Aldolase
BVELS4_RS09420	COG1312	Catalyzes the dehydration of D-mannonate
BVELS4_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS09430	COG1609	Transcriptional regulator
BVELS4_RS09435	COG2271	Major facilitator Superfamily
BVELS4_RS09485	COG2205	protein histidine kinase activity
BVELS4_RS09490	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS09500	COG3507	Belongs to the glycosyl hydrolase 43 family
BVELS4_RS09525	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS09530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVELS4_RS09535	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVELS4_RS09540	COG2610	gluconate transmembrane transporter activity
BVELS4_RS09545	COG2124	cytochrome p450
BVELS4_RS09565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVELS4_RS09575	COG2246	polysaccharide biosynthetic process
BVELS4_RS09580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVELS4_RS09585	COG0586	Pfam SNARE associated Golgi protein
BVELS4_RS09590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVELS4_RS09595	COG1024	Enoyl-CoA hydratase
BVELS4_RS09600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVELS4_RS09605	COG0511	ligase activity, forming carbon-carbon bonds
BVELS4_RS09610	COG0439	Biotin carboxylase
BVELS4_RS09615	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS09620	COG1960	acyl-CoA dehydrogenase activity
BVELS4_RS09625	COG1649	PFAM Uncharacterised BCR, COG1649
BVELS4_RS09645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS09650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS09655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS09660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS09665	COG2027	D-alanyl-D-alanine carboxypeptidase
BVELS4_RS09670	COG2017	converts alpha-aldose to the beta-anomer
BVELS4_RS09675	COG0534	Mate efflux family protein
BVELS4_RS09690	COG0582	viral genome integration into host DNA
BVELS4_RS09695	COG0166	Belongs to the GPI family
BVELS4_RS09700	COG0405	Gamma-glutamyltransferase
BVELS4_RS09705	COG2814	Major facilitator Superfamily
BVELS4_RS09710	COG0640	Transcriptional regulator
BVELS4_RS09715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BVELS4_RS09725	COG0604	alcohol dehydrogenase
BVELS4_RS09730	COG0493	'glutamate synthase
BVELS4_RS09735	COG0069	glutamate synthase activity
BVELS4_RS09735	COG0067	glutamate synthase
BVELS4_RS09735	COG0070	glutamate synthase
BVELS4_RS09740	COG0583	DNA-binding transcription factor activity
BVELS4_RS09745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BVELS4_RS09765	COG0300	oxidoreductase activity
BVELS4_RS09770	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BVELS4_RS09780	COG2814	Major facilitator Superfamily
BVELS4_RS09785	COG1070	Carbohydrate kinase
BVELS4_RS09790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVELS4_RS09795	COG0243	molybdopterin cofactor binding
BVELS4_RS09830	COG4974	Belongs to the 'phage' integrase family
BVELS4_RS09865	COG5632	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS09895	COG5434	Belongs to the glycosyl hydrolase 28 family
BVELS4_RS09910	COG5412	phage tail tape measure protein
BVELS4_RS09910	COG3953	SLT domain
BVELS4_RS10035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVELS4_RS10040	COG0662	Cupin 2, conserved barrel domain protein
BVELS4_RS10040	COG2207	Transcriptional regulator
BVELS4_RS10045	COG1309	transcriptional regulator
BVELS4_RS10050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVELS4_RS10060	COG0640	Transcriptional regulator
BVELS4_RS10065	COG0741	lytic transglycosylase activity
BVELS4_RS10070	COG2322	membrane
BVELS4_RS10085	COG1619	proteins homologs of microcin C7 resistance protein MccF
BVELS4_RS10095	COG1388	LysM domain
BVELS4_RS10095	COG3584	3D domain protein
BVELS4_RS10100	COG0514	ATP-dependent DNA helicase (RecQ)
BVELS4_RS10110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVELS4_RS10115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVELS4_RS10130	COG0071	Belongs to the small heat shock protein (HSP20) family
BVELS4_RS10160	COG1012	belongs to the aldehyde dehydrogenase family
BVELS4_RS10170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVELS4_RS10175	COG0733	neurotransmitter:sodium symporter activity
BVELS4_RS10180	COG0385	Bile acid
BVELS4_RS10185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVELS4_RS10190	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVELS4_RS10200	COG4548	von Willebrand factor, type A
BVELS4_RS10205	COG0714	Associated with various cellular activities
BVELS4_RS10210	COG2032	superoxide dismutase activity
BVELS4_RS10215	COG0791	NLP P60 protein
BVELS4_RS10215	COG1388	LysM domain
BVELS4_RS10220	COG1819	glycosyl
BVELS4_RS10225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BVELS4_RS10230	COG0534	Mate efflux family protein
BVELS4_RS10235	COG1366	Belongs to the anti-sigma-factor antagonist family
BVELS4_RS10240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BVELS4_RS10245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BVELS4_RS10255	COG2962	Rard protein
BVELS4_RS10270	COG1942	4-Oxalocrotonate Tautomerase
BVELS4_RS10280	COG1733	regulation of RNA biosynthetic process
BVELS4_RS10285	COG0778	Nitroreductase
BVELS4_RS10290	COG0400	carboxylic ester hydrolase activity
BVELS4_RS10295	COG0346	lactoylglutathione lyase activity
BVELS4_RS10305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVELS4_RS10315	COG2723	6-phospho-beta-galactosidase activity
BVELS4_RS10320	COG2188	Transcriptional regulator
BVELS4_RS10325	COG0793	Belongs to the peptidase S41A family
BVELS4_RS10325	COG3409	Peptidoglycan-binding domain 1 protein
BVELS4_RS10330	COG2226	methyltransferase
BVELS4_RS10340	COG1876	peptidase activity
BVELS4_RS10360	COG0671	phosphoesterase, PA-phosphatase related
BVELS4_RS10395	COG1509	lysine 2,3-aminomutase activity
BVELS4_RS10400	COG0456	acetyltransferase
BVELS4_RS10405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVELS4_RS10410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVELS4_RS10415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVELS4_RS10420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVELS4_RS10435	COG0456	acetyltransferase
BVELS4_RS10440	COG0463	Glycosyl transferase, family 2
BVELS4_RS10455	COG4641	Protein conserved in bacteria
BVELS4_RS10465	COG1086	Polysaccharide biosynthesis protein
BVELS4_RS10510	COG1012	belongs to the aldehyde dehydrogenase family
BVELS4_RS10530	COG4282	regulation of fungal-type cell wall biogenesis
BVELS4_RS10535	COG1525	nuclease
BVELS4_RS10540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BVELS4_RS10560	COG1846	Transcriptional regulator
BVELS4_RS10565	COG4698	Protein conserved in bacteria
BVELS4_RS10570	COG2755	lipolytic protein G-D-S-L family
BVELS4_RS10575	COG1999	signal sequence binding
BVELS4_RS10585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVELS4_RS10590	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BVELS4_RS10595	COG1272	protein, Hemolysin III
BVELS4_RS10600	COG0204	Acyl-transferase
BVELS4_RS10605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BVELS4_RS10620	COG2521	methyltransferase
BVELS4_RS10620	COG2136	Putative SAM-dependent methyltransferase
BVELS4_RS10635	COG1413	lyase activity
BVELS4_RS10640	COG1418	mRNA catabolic process
BVELS4_RS10645	COG0386	Belongs to the glutathione peroxidase family
BVELS4_RS10655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVELS4_RS10665	COG1278	Cold shock
BVELS4_RS10685	COG0328	RNA-DNA hybrid ribonuclease activity
BVELS4_RS10690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BVELS4_RS10695	COG0328	RNA-DNA hybrid ribonuclease activity
BVELS4_RS10705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVELS4_RS10720	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BVELS4_RS10730	COG1755	Isoprenylcysteine carboxyl methyltransferase
BVELS4_RS10735	COG3424	synthase
BVELS4_RS10755	COG2323	membrane
BVELS4_RS10760	COG1335	isochorismatase
BVELS4_RS10770	COG2233	PERMEase
BVELS4_RS10780	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BVELS4_RS10785	COG1199	ATP-dependent helicase activity
BVELS4_RS10800	COG0116	Belongs to the methyltransferase superfamily
BVELS4_RS10830	COG3359	exonuclease
BVELS4_RS10835	COG1205	dead DEAH box helicase
BVELS4_RS10835	COG1111	helicase
BVELS4_RS10840	COG2190	(PTS) system
BVELS4_RS10845	COG0071	Belongs to the small heat shock protein (HSP20) family
BVELS4_RS10885	COG4499	WXG100 protein secretion system (Wss), protein YukC
BVELS4_RS10885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVELS4_RS10895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVELS4_RS10900	COG3935	DnaD domain protein
BVELS4_RS10910	COG0436	Aminotransferase
BVELS4_RS10915	COG5353	protein conserved in bacteria
BVELS4_RS10925	COG1199	ATP-dependent helicase activity
BVELS4_RS10925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVELS4_RS10955	COG0438	transferase activity, transferring glycosyl groups
BVELS4_RS10960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BVELS4_RS10975	COG1694	Mazg nucleotide pyrophosphohydrolase
BVELS4_RS10980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVELS4_RS10985	COG2140	Oxalate decarboxylase
BVELS4_RS10995	COG4347	Protein of unknown function (DUF1405)
BVELS4_RS11000	COG2010	Cytochrome c
BVELS4_RS11000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BVELS4_RS11005	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BVELS4_RS11010	COG0723	plastoquinol--plastocyanin reductase activity
BVELS4_RS11025	COG0457	Tetratricopeptide repeat
BVELS4_RS11040	COG0287	Prephenate dehydrogenase
BVELS4_RS11075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BVELS4_RS11080	COG4401	Chorismate mutase type I
BVELS4_RS11095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BVELS4_RS11100	COG0105	UTP biosynthetic process
BVELS4_RS11105	COG0142	geranyltranstransferase activity
BVELS4_RS11115	COG0142	geranyltranstransferase activity
BVELS4_RS11130	COG0776	regulation of translation
BVELS4_RS11135	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BVELS4_RS11175	COG0539	negative regulation of cytoplasmic translation
BVELS4_RS11190	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BVELS4_RS11195	COG2959	enzyme of heme biosynthesis
BVELS4_RS11200	COG3773	Cell wall hydrolase
BVELS4_RS11200	COG3409	Peptidoglycan-binding domain 1 protein
BVELS4_RS11205	COG2339	peptidase activity
BVELS4_RS11210	COG0492	ferredoxin-NADP+ reductase activity
BVELS4_RS11215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVELS4_RS11220	COG4862	establishment of competence for transformation
BVELS4_RS11225	COG1408	metallophosphoesterase
BVELS4_RS11235	COG1388	LysM domain
BVELS4_RS11240	COG1266	CAAX protease self-immunity
BVELS4_RS11245	COG0514	ATP-dependent DNA helicase (RecQ)
BVELS4_RS11250	COG4955	Helix-turn-helix domain
BVELS4_RS11255	COG1141	Ferredoxin
BVELS4_RS11260	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BVELS4_RS11265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVELS4_RS11275	COG1595	DNA-templated transcription, initiation
BVELS4_RS11280	COG5002	protein histidine kinase activity
BVELS4_RS11285	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS11290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVELS4_RS11295	COG1333	cytochrome c biogenesis protein
BVELS4_RS11300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVELS4_RS11305	COG1187	pseudouridine synthase activity
BVELS4_RS11310	COG0700	Nucleoside recognition
BVELS4_RS11315	COG2715	membrane protein required for spore maturation
BVELS4_RS11320	COG1686	Belongs to the peptidase S11 family
BVELS4_RS11345	COG1547	Domain of unknown function (DUF309)
BVELS4_RS11350	COG0456	acetyltransferase
BVELS4_RS11365	COG0307	riboflavin synthase, alpha
BVELS4_RS11370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVELS4_RS11370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVELS4_RS11380	COG0681	Belongs to the peptidase S26 family
BVELS4_RS11390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVELS4_RS11395	COG4086	secreted protein
BVELS4_RS11400	COG0019	diaminopimelate decarboxylase activity
BVELS4_RS11405	COG0697	spore germination
BVELS4_RS11420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVELS4_RS11440	COG1191	sigma factor activity
BVELS4_RS11450	COG1366	Belongs to the anti-sigma-factor antagonist family
BVELS4_RS11455	COG1686	Belongs to the peptidase S11 family
BVELS4_RS11460	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BVELS4_RS11465	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BVELS4_RS11470	COG4974	Belongs to the 'phage' integrase family
BVELS4_RS11480	COG0735	belongs to the Fur family
BVELS4_RS11485	COG1300	Membrane
BVELS4_RS11500	COG0281	malic enzyme
BVELS4_RS11505	COG1757	Na H antiporter
BVELS4_RS11510	COG1027	Aspartate ammonia-lyase
BVELS4_RS11515	COG0252	asparaginase activity
BVELS4_RS11520	COG1396	sequence-specific DNA binding
BVELS4_RS11525	COG1379	DNA repair
BVELS4_RS11530	COG0494	nUDIX hydrolase
BVELS4_RS11540	COG0667	Aldo Keto reductase
BVELS4_RS11550	COG1073	alpha beta
BVELS4_RS11560	COG4918	Iron-sulphur cluster biosynthesis
BVELS4_RS11565	COG0456	acetyltransferase
BVELS4_RS11565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BVELS4_RS11570	COG2329	Antibiotic biosynthesis monooxygenase
BVELS4_RS11575	COG0456	acetyltransferase
BVELS4_RS11580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVELS4_RS11595	COG0628	permease
BVELS4_RS11605	COG0346	lactoylglutathione lyase activity
BVELS4_RS11615	COG3048	D-serine ammonia-lyase activity
BVELS4_RS11620	COG0300	oxidoreductase activity
BVELS4_RS11625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVELS4_RS11630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVELS4_RS11635	COG1024	Enoyl-CoA hydratase
BVELS4_RS11640	COG3425	synthase
BVELS4_RS11645	COG2124	cytochrome p450
BVELS4_RS11650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS11650	COG3321	synthase
BVELS4_RS11650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS11650	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS11650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVELS4_RS11655	COG3321	synthase
BVELS4_RS11655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS11655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVELS4_RS11655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS11660	COG3321	synthase
BVELS4_RS11660	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS11660	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS11660	COG0300	oxidoreductase activity
BVELS4_RS11660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS11665	COG0300	oxidoreductase activity
BVELS4_RS11665	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS11665	COG3321	synthase
BVELS4_RS11665	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS11665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS11670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVELS4_RS11670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS11670	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS11670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS11670	COG3321	synthase
BVELS4_RS11675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS11675	COG3321	synthase
BVELS4_RS11675	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS11675	COG0300	oxidoreductase activity
BVELS4_RS11680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVELS4_RS11680	COG3321	synthase
BVELS4_RS11680	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS11680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS11680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVELS4_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS11690	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS11705	COG2070	2-Nitropropane dioxygenase
BVELS4_RS11705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVELS4_RS11710	COG0250	Participates in transcription elongation, termination and antitermination
BVELS4_RS11730	COG0596	Alpha beta hydrolase
BVELS4_RS11745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVELS4_RS11750	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BVELS4_RS11765	COG0706	membrane insertase activity
BVELS4_RS11770	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVELS4_RS11775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVELS4_RS11780	COG0346	lactoylglutathione lyase activity
BVELS4_RS11790	COG1376	ErfK ybiS ycfS ynhG family protein
BVELS4_RS11795	COG4129	membrane
BVELS4_RS11800	COG1126	abc transporter atp-binding protein
BVELS4_RS11805	COG0765	amino acid transport
BVELS4_RS11810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVELS4_RS11820	COG1597	lipid kinase activity
BVELS4_RS11825	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVELS4_RS11830	COG0022	dehydrogenase e1 component
BVELS4_RS11835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVELS4_RS11840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVELS4_RS11845	COG3426	butyrate kinase activity
BVELS4_RS11850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVELS4_RS11855	COG0280	phosphate acetyltransferase
BVELS4_RS11860	COG3290	protein histidine kinase activity
BVELS4_RS11860	COG3829	transcription factor binding
BVELS4_RS11870	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BVELS4_RS11875	COG2079	MmgE PrpD family protein
BVELS4_RS11880	COG0372	Belongs to the citrate synthase family
BVELS4_RS11885	COG1960	acyl-CoA dehydrogenase activity
BVELS4_RS11890	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVELS4_RS11895	COG0183	Belongs to the thiolase family
BVELS4_RS11900	COG0584	glycerophosphoryl diester phosphodiesterase
BVELS4_RS11905	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS11930	COG1902	pentaerythritol trinitrate reductase activity
BVELS4_RS11945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVELS4_RS11950	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS11955	COG0750	zinc metalloprotease
BVELS4_RS11960	COG0497	DNA recombination
BVELS4_RS11970	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BVELS4_RS11980	COG0142	geranyltranstransferase activity
BVELS4_RS11990	COG1570	exodeoxyribonuclease VII activity
BVELS4_RS12005	COG1302	Protein conserved in bacteria
BVELS4_RS12010	COG0439	Biotin carboxylase
BVELS4_RS12015	COG0511	ligase activity, forming carbon-carbon bonds
BVELS4_RS12055	COG3854	ATPases associated with a variety of cellular activities
BVELS4_RS12070	COG0006	proline dipeptidase activity
BVELS4_RS12080	COG3872	metal-dependent enzyme
BVELS4_RS12090	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVELS4_RS12105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVELS4_RS12125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVELS4_RS12140	COG1396	sequence-specific DNA binding
BVELS4_RS12150	COG0681	Belongs to the peptidase S26 family
BVELS4_RS12175	COG4940	Competence protein ComGF
BVELS4_RS12185	COG4970	Tfp pilus assembly protein FimT
BVELS4_RS12190	COG4537	Required for transformation and DNA binding
BVELS4_RS12195	COG1459	type II secretion system
BVELS4_RS12200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVELS4_RS12205	COG0598	Magnesium transport protein CorA
BVELS4_RS12215	COG1366	Belongs to the anti-sigma-factor antagonist family
BVELS4_RS12225	COG1393	Belongs to the ArsC family
BVELS4_RS12235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVELS4_RS12245	COG0011	TIGRFAM Protein of
BVELS4_RS12255	COG2866	Carboxypeptidase
BVELS4_RS12260	COG1940	carbohydrate kinase activity
BVELS4_RS12265	COG4483	Protein conserved in bacteria
BVELS4_RS12270	COG1757	Na H antiporter
BVELS4_RS12280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVELS4_RS12295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVELS4_RS12300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVELS4_RS12305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVELS4_RS12310	COG0581	inorganic phosphate transmembrane transporter activity
BVELS4_RS12315	COG0573	inorganic phosphate transmembrane transporter activity
BVELS4_RS12320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BVELS4_RS12330	COG0477	Major facilitator Superfamily
BVELS4_RS12335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVELS4_RS12340	COG2839	Protein conserved in bacteria
BVELS4_RS12345	COG5521	maltodextrose utilization protein MalA
BVELS4_RS12350	COG1388	LysM domain
BVELS4_RS12360	COG4709	membrane
BVELS4_RS12365	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BVELS4_RS12370	COG0735	belongs to the Fur family
BVELS4_RS12375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVELS4_RS12390	COG0513	Belongs to the DEAD box helicase family
BVELS4_RS12405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVELS4_RS12410	COG2384	SAM-dependent methyltransferase
BVELS4_RS12415	COG2010	Cytochrome c
BVELS4_RS12420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVELS4_RS12425	COG0358	DNA primase activity
BVELS4_RS12440	COG0517	IMP dehydrogenase activity
BVELS4_RS12445	COG0751	glycine-tRNA ligase activity
BVELS4_RS12465	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVELS4_RS12470	COG0295	cytidine deaminase activity
BVELS4_RS12475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BVELS4_RS12485	COG1480	7TM receptor with intracellular HD hydrolase
BVELS4_RS12490	COG1702	phosphate starvation-inducible protein PhoH
BVELS4_RS12495	COG0561	phosphatase activity
BVELS4_RS12510	COG4864	UPF0365 protein
BVELS4_RS12515	COG1030	water channel activity
BVELS4_RS12520	COG1610	YqeY-like protein
BVELS4_RS12530	COG1283	sodium-dependent phosphate transmembrane transporter activity
BVELS4_RS12535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVELS4_RS12540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVELS4_RS12570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVELS4_RS12585	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS12600	COG1466	dna polymerase III delta subunit
BVELS4_RS12615	COG2333	competence protein COMEC
BVELS4_RS12615	COG0658	competence protein
BVELS4_RS12620	COG2131	deaminase
BVELS4_RS12625	COG1555	photosystem II stabilization
BVELS4_RS12625	COG1596	polysaccharide export
BVELS4_RS12630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVELS4_RS12635	COG2226	methyltransferase
BVELS4_RS12640	COG0799	negative regulation of ribosome biogenesis
BVELS4_RS12645	COG1713	HD superfamily hydrolase involved in NAD metabolism
BVELS4_RS12655	COG1534	Rna-binding protein
BVELS4_RS12660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BVELS4_RS12665	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BVELS4_RS12670	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BVELS4_RS12680	COG2755	lipolytic protein G-D-S-L family
BVELS4_RS12690	COG0398	Pfam SNARE associated Golgi protein
BVELS4_RS12720	COG3708	Transcriptional regulator
BVELS4_RS12720	COG2207	Transcriptional regulator
BVELS4_RS12730	COG0563	adenylate kinase activity
BVELS4_RS12740	COG2814	Major facilitator Superfamily
BVELS4_RS12750	COG0456	acetyltransferase
BVELS4_RS12755	COG2318	DinB family
BVELS4_RS12765	COG0561	phosphatase activity
BVELS4_RS12780	COG1482	cell wall glycoprotein biosynthetic process
BVELS4_RS12785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVELS4_RS12785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVELS4_RS12785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVELS4_RS12790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVELS4_RS12790	COG3711	transcriptional antiterminator
BVELS4_RS12800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVELS4_RS12805	COG0583	DNA-binding transcription factor activity
BVELS4_RS12810	COG2814	Major facilitator Superfamily
BVELS4_RS12815	COG2124	cytochrome p450
BVELS4_RS12815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BVELS4_RS12820	COG1309	transcriptional regulator
BVELS4_RS12825	COG2226	methyltransferase
BVELS4_RS12840	COG2116	formate transmembrane transporter activity
BVELS4_RS12845	COG5609	conserved protein (DUF2294)
BVELS4_RS12850	COG3383	formate dehydrogenase (NAD+) activity
BVELS4_RS12855	COG2427	Protein of unknown function (DUF1641)
BVELS4_RS12865	COG0626	cystathionine gamma-synthase activity
BVELS4_RS12870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVELS4_RS12895	COG0768	penicillin binding
BVELS4_RS12915	COG5632	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS12915	COG3409	Peptidoglycan-binding domain 1 protein
BVELS4_RS12945	COG5434	Belongs to the glycosyl hydrolase 28 family
BVELS4_RS12950	COG1705	Flagellar rod assembly protein muramidase FlgJ
BVELS4_RS12960	COG3953	SLT domain
BVELS4_RS12960	COG5280	Phage tail tape measure protein TP901
BVELS4_RS13015	COG1802	Transcriptional regulator
BVELS4_RS13015	COG4626	Terminase
BVELS4_RS13045	COG0582	viral genome integration into host DNA
BVELS4_RS13050	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVELS4_RS13210	COG1396	sequence-specific DNA binding
BVELS4_RS13240	COG4122	O-methyltransferase activity
BVELS4_RS13245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVELS4_RS13270	COG0628	permease
BVELS4_RS13275	COG1126	abc transporter atp-binding protein
BVELS4_RS13280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVELS4_RS13285	COG0765	amino acid transport
BVELS4_RS13290	COG0765	amino acid transport
BVELS4_RS13305	COG3881	PFAM PRC-barrel domain
BVELS4_RS13310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVELS4_RS13315	COG0457	Tetratricopeptide repeat
BVELS4_RS13325	COG1104	cysteine desulfurase activity
BVELS4_RS13330	COG1959	2 iron, 2 sulfur cluster binding
BVELS4_RS13335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVELS4_RS13340	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVELS4_RS13365	COG4991	sh3 domain protein
BVELS4_RS13365	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS13365	COG3103	Sh3 type 3 domain protein
BVELS4_RS13375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVELS4_RS13385	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BVELS4_RS13385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVELS4_RS13390	COG5416	Lipopolysaccharide assembly protein A domain
BVELS4_RS13395	COG0490	domain, Protein
BVELS4_RS13400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVELS4_RS13400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVELS4_RS13410	COG2244	polysaccharide biosynthetic process
BVELS4_RS13415	COG2323	membrane
BVELS4_RS13425	COG1862	Preprotein translocase
BVELS4_RS13465	COG1388	LysM domain
BVELS4_RS13475	COG0157	Belongs to the NadC ModD family
BVELS4_RS13480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BVELS4_RS13485	COG1104	cysteine desulfurase activity
BVELS4_RS13490	COG1827	regulation of RNA biosynthetic process
BVELS4_RS13495	COG0077	Prephenate dehydratase
BVELS4_RS13510	COG3290	protein histidine kinase activity
BVELS4_RS13515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BVELS4_RS13520	COG2868	ribosomal protein
BVELS4_RS13530	COG1994	Peptidase M50
BVELS4_RS13535	COG0739	heme binding
BVELS4_RS13540	COG2894	cell division
BVELS4_RS13550	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BVELS4_RS13560	COG1077	Cell shape determining protein MreB Mrl
BVELS4_RS13580	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BVELS4_RS13585	COG0285	dihydrofolate synthase activity
BVELS4_RS13590	COG0525	valine-tRNA ligase activity
BVELS4_RS13600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVELS4_RS13605	COG1388	LysM domain
BVELS4_RS13615	COG0113	porphobilinogen synthase activity
BVELS4_RS13620	COG1587	Uroporphyrinogen-III synthase
BVELS4_RS13630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVELS4_RS13650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVELS4_RS13655	COG0470	DNA polymerase III
BVELS4_RS13655	COG1067	ATP-dependent peptidase activity
BVELS4_RS13670	COG1477	protein flavinylation
BVELS4_RS13670	COG0457	Tetratricopeptide repeat
BVELS4_RS13685	COG0473	3-isopropylmalate dehydrogenase activity
BVELS4_RS13700	COG0440	acetolactate synthase activity
BVELS4_RS13705	COG0028	Belongs to the TPP enzyme family
BVELS4_RS13730	COG0622	Phosphoesterase
BVELS4_RS13735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BVELS4_RS13745	COG5401	PFAM Sporulation and spore germination
BVELS4_RS13755	COG1846	Transcriptional regulator
BVELS4_RS13760	COG2197	response regulator
BVELS4_RS13765	COG0824	Thioesterase
BVELS4_RS13770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BVELS4_RS13775	COG1053	succinate dehydrogenase
BVELS4_RS13780	COG2009	succinate dehydrogenase
BVELS4_RS13785	COG1719	4-vinyl reductase, 4VR
BVELS4_RS13790	COG0527	aspartate kinase activity
BVELS4_RS13800	COG3118	belongs to the thioredoxin family
BVELS4_RS13805	COG3534	alpha-L-arabinofuranosidase
BVELS4_RS13810	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BVELS4_RS13815	COG2086	electron transfer activity
BVELS4_RS13820	COG1024	Enoyl-CoA hydratase
BVELS4_RS13825	COG1309	transcriptional regulator
BVELS4_RS13830	COG0318	PFAM AMP-dependent synthetase and ligase
BVELS4_RS13840	COG3766	membrane
BVELS4_RS13850	COG1796	DNA polymerase
BVELS4_RS13850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BVELS4_RS13855	COG1286	toxin biosynthetic process
BVELS4_RS13870	COG0072	phenylalanine-tRNA ligase activity
BVELS4_RS13870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVELS4_RS13875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BVELS4_RS13880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVELS4_RS13890	COG3835	regulator
BVELS4_RS13895	COG0277	FAD linked oxidase domain protein
BVELS4_RS13900	COG0247	lactate metabolic process
BVELS4_RS13905	COG1966	Carbon starvation protein
BVELS4_RS13910	COG3534	alpha-L-arabinofuranosidase
BVELS4_RS13915	COG0395	ABC-type sugar transport system, permease component
BVELS4_RS13920	COG1175	transmembrane transport
BVELS4_RS13925	COG1653	transport
BVELS4_RS13935	COG0647	UMP catabolic process
BVELS4_RS13940	COG0235	Class ii aldolase
BVELS4_RS13945	COG1069	ribulokinase activity
BVELS4_RS13950	COG2160	L-arabinose isomerase activity
BVELS4_RS13955	COG3507	Belongs to the glycosyl hydrolase 43 family
BVELS4_RS13960	COG1363	Peptidase, m42
BVELS4_RS13970	COG3326	Membrane
BVELS4_RS13975	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BVELS4_RS13985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BVELS4_RS13990	COG1346	cytolysis
BVELS4_RS13995	COG1380	Effector of murein hydrolase LrgA
BVELS4_RS14000	COG3279	Response regulator of the LytR AlgR family
BVELS4_RS14005	COG3275	phosphorelay sensor kinase activity
BVELS4_RS14010	COG1011	Hydrolase
BVELS4_RS14025	COG0398	Pfam SNARE associated Golgi protein
BVELS4_RS14030	COG1484	DNA-dependent DNA replication
BVELS4_RS14035	COG3611	Membrane attachment protein
BVELS4_RS14050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVELS4_RS14055	COG1733	regulation of RNA biosynthetic process
BVELS4_RS14060	COG2814	Major facilitator Superfamily
BVELS4_RS14065	COG0656	L-ascorbic acid biosynthetic process
BVELS4_RS14070	COG0237	dephospho-CoA kinase activity
BVELS4_RS14075	COG1971	Probably functions as a manganese efflux pump
BVELS4_RS14080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BVELS4_RS14085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVELS4_RS14085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVELS4_RS14090	COG5002	protein histidine kinase activity
BVELS4_RS14095	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS14105	COG0538	isocitrate dehydrogenase activity
BVELS4_RS14110	COG0372	Belongs to the citrate synthase family
BVELS4_RS14135	COG0628	permease
BVELS4_RS14140	COG3030	protein affecting phage T7 exclusion by the F plasmid
BVELS4_RS14145	COG0469	pyruvate kinase activity
BVELS4_RS14165	COG0281	malic enzyme
BVELS4_RS14170	COG0587	DNA-directed DNA polymerase activity
BVELS4_RS14190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BVELS4_RS14200	COG4109	DRTGG domain
BVELS4_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS14225	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVELS4_RS14240	COG0827	DNA restriction-modification system
BVELS4_RS14245	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BVELS4_RS14250	COG3874	Sporulation protein YtfJ
BVELS4_RS14260	COG1714	RDD family
BVELS4_RS14265	COG0616	signal peptide processing
BVELS4_RS14270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVELS4_RS14275	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BVELS4_RS14280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVELS4_RS14295	COG1104	cysteine desulfurase activity
BVELS4_RS14300	COG1114	Component of the transport system for branched-chain amino acids
BVELS4_RS14310	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BVELS4_RS14315	COG1309	transcriptional regulator
BVELS4_RS14320	COG1956	GAF domain-containing protein
BVELS4_RS14325	COG2199	diguanylate cyclase activity
BVELS4_RS14325	COG2203	Gaf domain
BVELS4_RS14340	COG1012	belongs to the aldehyde dehydrogenase family
BVELS4_RS14365	COG1017	nitric oxide dioxygenase activity
BVELS4_RS14365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVELS4_RS14380	COG0693	protein deglycase activity
BVELS4_RS14395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVELS4_RS14400	COG1378	Sugar-specific transcriptional regulator TrmB
BVELS4_RS14420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVELS4_RS14425	COG0454	-acetyltransferase
BVELS4_RS14430	COG0517	IMP dehydrogenase activity
BVELS4_RS14435	COG0123	including yeast histone deacetylase and acetoin utilization protein
BVELS4_RS14440	COG1360	Flagellar Motor Protein
BVELS4_RS14445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVELS4_RS14450	COG1609	Transcriptional regulator
BVELS4_RS14455	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BVELS4_RS14455	COG1605	Chorismate mutase
BVELS4_RS14460	COG3118	belongs to the thioredoxin family
BVELS4_RS14465	COG4980	gas vesicle protein
BVELS4_RS14470	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BVELS4_RS14480	COG1674	ftsk spoiiie
BVELS4_RS14485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVELS4_RS14495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVELS4_RS14505	COG1363	Peptidase, m42
BVELS4_RS14510	COG5584	Small secreted protein
BVELS4_RS14515	COG0281	malic enzyme
BVELS4_RS14520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVELS4_RS14535	COG0510	thiamine kinase activity
BVELS4_RS14540	COG1597	lipid kinase activity
BVELS4_RS14550	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BVELS4_RS14555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVELS4_RS14560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVELS4_RS14565	COG2252	PERMEase
BVELS4_RS14570	COG4473	ABC transporter
BVELS4_RS14575	COG1131	(ABC) transporter
BVELS4_RS14580	COG1349	DNA-binding transcription factor activity
BVELS4_RS14585	COG1187	pseudouridine synthase activity
BVELS4_RS14590	COG2244	polysaccharide biosynthetic process
BVELS4_RS14595	COG2081	HI0933 family
BVELS4_RS14600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVELS4_RS14610	COG1609	Transcriptional regulator
BVELS4_RS14615	COG1653	transport
BVELS4_RS14620	COG1175	transmembrane transport
BVELS4_RS14625	COG0395	ABC-type sugar transport system, permease component
BVELS4_RS14630	COG1486	melibiose metabolic process
BVELS4_RS14640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVELS4_RS14655	COG2202	Pas domain
BVELS4_RS14655	COG1366	Belongs to the anti-sigma-factor antagonist family
BVELS4_RS14660	COG2814	Major facilitator Superfamily
BVELS4_RS14665	COG5522	Integral membrane protein (intg_mem_TP0381)
BVELS4_RS14670	COG0577	efflux transmembrane transporter activity
BVELS4_RS14675	COG1136	(ABC) transporter
BVELS4_RS14680	COG2205	protein histidine kinase activity
BVELS4_RS14685	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS14690	COG0577	efflux transmembrane transporter activity
BVELS4_RS14695	COG1136	(ABC) transporter
BVELS4_RS14715	COG1131	(ABC) transporter
BVELS4_RS14720	COG1725	Transcriptional regulator
BVELS4_RS14730	COG1242	4 iron, 4 sulfur cluster binding
BVELS4_RS14735	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BVELS4_RS14750	COG2267	carboxylic ester hydrolase activity
BVELS4_RS14755	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVELS4_RS14760	COG1113	amino acid transport
BVELS4_RS14765	COG0367	asparagine synthase
BVELS4_RS14785	COG1506	peptidase
BVELS4_RS14790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVELS4_RS14795	COG1116	anion transmembrane transporter activity
BVELS4_RS14800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVELS4_RS14805	COG0494	nUDIX hydrolase
BVELS4_RS14810	COG4824	toxin secretion phage lysis holin
BVELS4_RS14815	COG0783	Belongs to the Dps family
BVELS4_RS14840	COG0288	reversible hydration of carbon dioxide
BVELS4_RS14850	COG1271	oxidase subunit
BVELS4_RS14855	COG1294	oxidase, subunit
BVELS4_RS14865	COG4948	Mandelate Racemase Muconate Lactonizing
BVELS4_RS14875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BVELS4_RS14880	COG0596	Alpha beta hydrolase
BVELS4_RS14890	COG1169	isochorismate synthase
BVELS4_RS14895	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVELS4_RS14900	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BVELS4_RS15025	COG3859	Proton-coupled thiamine transporter YuaJ
BVELS4_RS15030	COG2268	Band 7 protein
BVELS4_RS15035	COG1585	Membrane protein implicated in regulation of membrane protease activity
BVELS4_RS15040	COG2318	DinB family
BVELS4_RS15050	COG1454	alcohol dehydrogenase
BVELS4_RS15055	COG1012	belongs to the aldehyde dehydrogenase family
BVELS4_RS15060	COG1510	regulation of RNA biosynthetic process
BVELS4_RS15070	COG0569	domain protein
BVELS4_RS15075	COG1705	Flagellar rod assembly protein muramidase FlgJ
BVELS4_RS15080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVELS4_RS15080	COG1017	nitric oxide dioxygenase activity
BVELS4_RS15105	COG0628	permease
BVELS4_RS15110	COG0673	inositol 2-dehydrogenase activity
BVELS4_RS15115	COG0693	protein deglycase activity
BVELS4_RS15120	COG0840	transmembrane signaling receptor activity
BVELS4_RS15125	COG0840	transmembrane signaling receptor activity
BVELS4_RS15130	COG0840	transmembrane signaling receptor activity
BVELS4_RS15135	COG0840	transmembrane signaling receptor activity
BVELS4_RS15150	COG2070	2-Nitropropane dioxygenase
BVELS4_RS15155	COG0432	Pfam Uncharacterised protein family UPF0047
BVELS4_RS15160	COG0366	Alpha amylase catalytic
BVELS4_RS15165	COG1253	flavin adenine dinucleotide binding
BVELS4_RS15170	COG2738	Putative neutral zinc metallopeptidase
BVELS4_RS15185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVELS4_RS15210	COG1335	isochorismatase
BVELS4_RS15215	COG1979	alcohol dehydrogenase
BVELS4_RS15220	COG1979	alcohol dehydrogenase
BVELS4_RS15225	COG2155	Conserved Protein
BVELS4_RS15230	COG1098	S1 RNA binding domain
BVELS4_RS15235	COG0436	Aminotransferase
BVELS4_RS15240	COG1522	sequence-specific DNA binding
BVELS4_RS15245	COG2267	carboxylic ester hydrolase activity
BVELS4_RS15255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BVELS4_RS15260	COG2205	protein histidine kinase activity
BVELS4_RS15270	COG5018	Exonuclease
BVELS4_RS15275	COG2814	Major facilitator Superfamily
BVELS4_RS15280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVELS4_RS15285	COG3011	Protein conserved in bacteria
BVELS4_RS15295	COG3290	protein histidine kinase activity
BVELS4_RS15300	COG4565	transcriptional regulatory protein
BVELS4_RS15330	COG2111	Na H antiporter
BVELS4_RS15330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVELS4_RS15335	COG2111	Na H antiporter
BVELS4_RS15340	COG1006	Multisubunit Na H antiporter MnhC subunit
BVELS4_RS15345	COG0651	ATP synthesis coupled electron transport
BVELS4_RS15350	COG1863	multisubunit Na H antiporter MnhE subunit
BVELS4_RS15355	COG2212	antiporter activity
BVELS4_RS15360	COG1320	monovalent cation:proton antiporter activity
BVELS4_RS15365	COG2050	protein possibly involved in aromatic compounds catabolism
BVELS4_RS15370	COG2197	response regulator
BVELS4_RS15375	COG4585	Histidine kinase
BVELS4_RS15385	COG0142	geranyltranstransferase activity
BVELS4_RS15400	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BVELS4_RS15405	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BVELS4_RS15410	COG1335	isochorismatase
BVELS4_RS15415	COG5506	Protein of unknown function (DUF1694)
BVELS4_RS15430	COG0628	permease
BVELS4_RS15440	COG1418	mRNA catabolic process
BVELS4_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS15455	COG1511	domain protein
BVELS4_RS15460	COG1674	ftsk spoiiie
BVELS4_RS15460	COG0433	COG0433 Predicted ATPase
BVELS4_RS15465	COG4499	WXG100 protein secretion system (Wss), protein YukC
BVELS4_RS15470	COG5417	Belongs to the EsaB family
BVELS4_RS15475	COG4842	Belongs to the WXG100 family
BVELS4_RS15480	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BVELS4_RS15480	COG2508	Transcriptional regulator
BVELS4_RS15485	COG0686	Belongs to the AlaDH PNT family
BVELS4_RS15490	COG5634	Uncharacterized conserved protein (DUF2278)
BVELS4_RS15495	COG3251	PFAM MbtH domain protein
BVELS4_RS15500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVELS4_RS15505	COG1535	isochorismatase
BVELS4_RS15505	COG3433	isochorismatase activity
BVELS4_RS15510	COG1021	2,3-dihydroxybenzoate-AMP ligase
BVELS4_RS15515	COG1169	isochorismate synthase
BVELS4_RS15520	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS15525	COG2819	hydrolase of the alpha beta superfamily
BVELS4_RS15530	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BVELS4_RS15535	COG1268	BioY protein
BVELS4_RS15540	COG2056	Na+-H+ antiporter family
BVELS4_RS15550	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BVELS4_RS15555	COG3584	3D domain protein
BVELS4_RS15570	COG1252	NADH dehydrogenase
BVELS4_RS15600	COG1131	(ABC) transporter
BVELS4_RS15620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVELS4_RS15625	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BVELS4_RS15630	COG0316	Belongs to the HesB IscA family
BVELS4_RS15640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVELS4_RS15650	COG1252	NADH dehydrogenase
BVELS4_RS15655	COG4837	Protein of unknown function (DUF1462)
BVELS4_RS15660	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BVELS4_RS15665	COG0823	Involved in the tonB-independent uptake of proteins
BVELS4_RS15665	COG1506	peptidase
BVELS4_RS15665	COG4946	Tricorn protease homolog
BVELS4_RS15675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BVELS4_RS15680	COG0460	homoserine dehydrogenase
BVELS4_RS15685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVELS4_RS15690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BVELS4_RS15695	COG0647	UMP catabolic process
BVELS4_RS15700	COG2445	Protein of unknown function DUF86
BVELS4_RS15705	COG4470	Protein conserved in bacteria
BVELS4_RS15715	COG0739	heme binding
BVELS4_RS15725	COG0737	Belongs to the 5'-nucleotidase family
BVELS4_RS15730	COG0730	response to heat
BVELS4_RS15735	COG1801	Protein of unknown function DUF72
BVELS4_RS15750	COG2508	Transcriptional regulator
BVELS4_RS15770	COG2814	Major facilitator Superfamily
BVELS4_RS15775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BVELS4_RS15780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVELS4_RS15785	COG2356	endonuclease I
BVELS4_RS15790	COG3842	ATPase activity
BVELS4_RS15795	COG2188	Transcriptional regulator
BVELS4_RS15800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVELS4_RS15805	COG0395	ABC-type sugar transport system, permease component
BVELS4_RS15810	COG1175	transmembrane transport
BVELS4_RS15815	COG1653	transport
BVELS4_RS15820	COG2222	sugar isomerase
BVELS4_RS15825	COG0789	Transcriptional regulator
BVELS4_RS15850	COG0322	excinuclease ABC activity
BVELS4_RS15855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVELS4_RS15875	COG3409	Peptidoglycan-binding domain 1 protein
BVELS4_RS15880	COG0719	Fe-S assembly protein
BVELS4_RS15885	COG0822	iron-sulfur transferase activity
BVELS4_RS15890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVELS4_RS15895	COG0719	Fe-S assembly protein
BVELS4_RS15900	COG0396	ATPase activity
BVELS4_RS15910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVELS4_RS15915	COG1464	Belongs to the NlpA lipoprotein family
BVELS4_RS15920	COG2011	ABC-type metal ion transport system permease component
BVELS4_RS15925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVELS4_RS15935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVELS4_RS15940	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BVELS4_RS15955	COG1393	Belongs to the ArsC family
BVELS4_RS15960	COG1960	acyl-CoA dehydrogenase activity
BVELS4_RS15965	COG0183	Belongs to the thiolase family
BVELS4_RS15970	COG1024	Enoyl-CoA hydratase
BVELS4_RS15970	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVELS4_RS15990	COG5577	PFAM Coat F domain
BVELS4_RS15995	COG1846	Transcriptional regulator
BVELS4_RS16000	COG0477	Major facilitator Superfamily
BVELS4_RS16005	COG0583	DNA-binding transcription factor activity
BVELS4_RS16025	COG1120	ATPase activity
BVELS4_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS16045	COG0783	Belongs to the Dps family
BVELS4_RS16050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVELS4_RS16055	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS16060	COG2205	protein histidine kinase activity
BVELS4_RS16060	COG2770	Histidine kinase
BVELS4_RS16070	COG1309	transcriptional regulator
BVELS4_RS16075	COG0114	fumarate hydratase activity
BVELS4_RS16085	COG0697	spore germination
BVELS4_RS16090	COG0814	amino acid
BVELS4_RS16100	COG2197	response regulator
BVELS4_RS16105	COG4585	Histidine kinase
BVELS4_RS16110	COG4758	membrane
BVELS4_RS16115	COG3595	metallopeptidase activity
BVELS4_RS16120	COG1842	Phage shock protein A
BVELS4_RS16125	COG4758	membrane
BVELS4_RS16130	COG2814	Major facilitator Superfamily
BVELS4_RS16135	COG2096	Adenosyltransferase
BVELS4_RS16140	COG1120	ATPase activity
BVELS4_RS16145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVELS4_RS16150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVELS4_RS16155	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS16160	COG3386	PFAM SMP-30 Gluconolaconase
BVELS4_RS16165	COG2205	protein histidine kinase activity
BVELS4_RS16170	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS16180	COG1191	sigma factor activity
BVELS4_RS16190	COG2140	Oxalate decarboxylase
BVELS4_RS16200	COG1120	ATPase activity
BVELS4_RS16205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVELS4_RS16210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVELS4_RS16215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVELS4_RS16220	COG0531	amino acid
BVELS4_RS16230	COG1988	membrane-bound metal-dependent
BVELS4_RS16235	COG1368	sulfuric ester hydrolase activity
BVELS4_RS16240	COG1910	domain protein
BVELS4_RS16245	COG0725	ABC transporter, periplasmic molybdate-binding protein
BVELS4_RS16250	COG4149	molybdate abc transporter
BVELS4_RS16255	COG2197	response regulator
BVELS4_RS16260	COG3850	Histidine kinase
BVELS4_RS16265	COG1131	(ABC) transporter
BVELS4_RS16275	COG0842	Transport permease protein
BVELS4_RS16280	COG0656	L-ascorbic acid biosynthetic process
BVELS4_RS16300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BVELS4_RS16305	COG3973	AAA domain
BVELS4_RS16310	COG2860	membrane
BVELS4_RS16320	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BVELS4_RS16325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVELS4_RS16330	COG2217	Heavy metal translocating P-type atpase
BVELS4_RS16335	COG2217	Heavy metal translocating P-type atpase
BVELS4_RS16340	COG2608	mercury ion transmembrane transporter activity
BVELS4_RS16345	COG1937	Protein conserved in bacteria
BVELS4_RS16350	COG0673	inositol 2-dehydrogenase activity
BVELS4_RS16365	COG2814	Major facilitator Superfamily
BVELS4_RS16380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVELS4_RS16385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVELS4_RS16390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVELS4_RS16395	COG1126	abc transporter atp-binding protein
BVELS4_RS16400	COG0765	amino acid transport
BVELS4_RS16405	COG0765	amino acid transport
BVELS4_RS16410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVELS4_RS16415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVELS4_RS16420	COG0454	-acetyltransferase
BVELS4_RS16425	COG0583	DNA-binding transcription factor activity
BVELS4_RS16430	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS16435	COG2732	(Barnase) inhibitor
BVELS4_RS16450	COG0557	exoribonuclease II activity
BVELS4_RS16455	COG1647	Serine aminopeptidase, S33
BVELS4_RS16460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BVELS4_RS16465	COG1476	TRANSCRIPTIONal
BVELS4_RS16470	COG1396	sequence-specific DNA binding
BVELS4_RS16475	COG1396	sequence-specific DNA binding
BVELS4_RS16480	COG1733	regulation of RNA biosynthetic process
BVELS4_RS16505	COG1131	(ABC) transporter
BVELS4_RS16510	COG1174	glycine betaine transport
BVELS4_RS16515	COG1732	Glycine betaine
BVELS4_RS16520	COG1174	glycine betaine transport
BVELS4_RS16525	COG1125	glycine betaine transport
BVELS4_RS16525	COG0517	IMP dehydrogenase activity
BVELS4_RS16530	COG1510	regulation of RNA biosynthetic process
BVELS4_RS16535	COG1174	glycine betaine transport
BVELS4_RS16540	COG1732	Glycine betaine
BVELS4_RS16545	COG1174	glycine betaine transport
BVELS4_RS16550	COG1125	glycine betaine transport
BVELS4_RS16550	COG0517	IMP dehydrogenase activity
BVELS4_RS16555	COG1510	regulation of RNA biosynthetic process
BVELS4_RS16560	COG2095	MarC family integral membrane protein
BVELS4_RS16565	COG3064	Membrane
BVELS4_RS16570	COG4640	response to antibiotic
BVELS4_RS16575	COG0456	acetyltransferase
BVELS4_RS16590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BVELS4_RS16605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVELS4_RS16610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVELS4_RS16615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVELS4_RS16625	COG2234	aminopeptidase activity
BVELS4_RS16645	COG0126	phosphoglycerate kinase activity
BVELS4_RS16650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVELS4_RS16655	COG2390	Transcriptional regulator
BVELS4_RS16660	COG2814	Major facilitator Superfamily
BVELS4_RS16665	COG1609	Transcriptional regulator
BVELS4_RS16670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVELS4_RS16680	COG0583	DNA-binding transcription factor activity
BVELS4_RS16685	COG0697	spore germination
BVELS4_RS16690	COG1113	amino acid transport
BVELS4_RS16700	COG1609	Transcriptional regulator
BVELS4_RS16710	COG0561	phosphatase activity
BVELS4_RS16715	COG1737	Transcriptional regulator
BVELS4_RS16720	COG1070	Carbohydrate kinase
BVELS4_RS16745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVELS4_RS16750	COG2186	Transcriptional regulator
BVELS4_RS16755	COG1620	l-lactate permease
BVELS4_RS16760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BVELS4_RS16770	COG5039	Polysaccharide pyruvyl transferase
BVELS4_RS16775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVELS4_RS16780	COG0110	maltose O-acetyltransferase activity
BVELS4_RS16785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BVELS4_RS16790	COG2244	polysaccharide biosynthetic process
BVELS4_RS16795	COG1216	Glycosyl transferase, family 2
BVELS4_RS16800	COG5039	Polysaccharide pyruvyl transferase
BVELS4_RS16805	COG1216	Glycosyl transferase, family 2
BVELS4_RS16815	COG0438	transferase activity, transferring glycosyl groups
BVELS4_RS16820	COG1215	transferase activity, transferring glycosyl groups
BVELS4_RS16825	COG0438	transferase activity, transferring glycosyl groups
BVELS4_RS16830	COG1086	Polysaccharide biosynthesis protein
BVELS4_RS16835	COG0489	protein tyrosine kinase activity
BVELS4_RS16840	COG3944	biosynthesis protein
BVELS4_RS16845	COG1396	sequence-specific DNA binding
BVELS4_RS16850	COG2272	Belongs to the type-B carboxylesterase lipase family
BVELS4_RS16860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BVELS4_RS16865	COG2364	Membrane
BVELS4_RS16870	COG0456	acetyltransferase
BVELS4_RS16875	COG3479	Phenolic acid decarboxylase
BVELS4_RS16925	COG2223	nitrite transmembrane transporter activity
BVELS4_RS16930	COG1609	Transcriptional regulator
BVELS4_RS16940	COG0583	DNA-binding transcription factor activity
BVELS4_RS16945	COG2828	Protein conserved in bacteria
BVELS4_RS16950	COG0477	Major facilitator Superfamily
BVELS4_RS16950	COG2814	Major facilitator Superfamily
BVELS4_RS16955	COG1611	Belongs to the LOG family
BVELS4_RS16960	COG1694	Mazg nucleotide pyrophosphohydrolase
BVELS4_RS16965	COG0659	secondary active sulfate transmembrane transporter activity
BVELS4_RS16970	COG0288	reversible hydration of carbon dioxide
BVELS4_RS16980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVELS4_RS16985	COG4290	ribonuclease
BVELS4_RS17000	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BVELS4_RS17005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVELS4_RS17015	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BVELS4_RS17025	COG1051	belongs to the nudix hydrolase family
BVELS4_RS17030	COG0492	ferredoxin-NADP+ reductase activity
BVELS4_RS17035	COG0791	NLP P60 protein
BVELS4_RS17035	COG3883	PFAM NLP P60 protein
BVELS4_RS17040	COG0457	Tetratricopeptide repeat
BVELS4_RS17045	COG5002	protein histidine kinase activity
BVELS4_RS17050	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS17055	COG1132	(ABC) transporter
BVELS4_RS17060	COG0140	phosphoribosyl-ATP diphosphatase activity
BVELS4_RS17060	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BVELS4_RS17085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BVELS4_RS17100	COG4990	cell redox homeostasis
BVELS4_RS17105	COG0110	maltose O-acetyltransferase activity
BVELS4_RS17125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BVELS4_RS17135	COG2188	Transcriptional regulator
BVELS4_RS17140	COG1309	transcriptional regulator
BVELS4_RS17145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BVELS4_RS17150	COG1950	PFAM Membrane protein of
BVELS4_RS17155	COG1983	PspC domain protein
BVELS4_RS17160	COG3595	metallopeptidase activity
BVELS4_RS17175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BVELS4_RS17185	COG4897	Protein conserved in bacteria
BVELS4_RS17190	COG0574	Belongs to the PEP-utilizing enzyme family
BVELS4_RS17190	COG3848	Pyruvate phosphate dikinase
BVELS4_RS17195	COG1309	transcriptional regulator
BVELS4_RS17200	COG2814	Major facilitator Superfamily
BVELS4_RS17205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVELS4_RS17215	COG3409	Peptidoglycan-binding domain 1 protein
BVELS4_RS17215	COG0793	Belongs to the peptidase S41A family
BVELS4_RS17220	COG3420	alginic acid biosynthetic process
BVELS4_RS17225	COG2177	Part of the ABC transporter FtsEX involved in
BVELS4_RS17230	COG2884	Cell division ATP-binding protein ftsE
BVELS4_RS17235	COG2010	Cytochrome c
BVELS4_RS17240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVELS4_RS17255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BVELS4_RS17270	COG1516	flagellar protein fliS
BVELS4_RS17275	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BVELS4_RS17280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVELS4_RS17300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVELS4_RS17305	COG1256	bacterial-type flagellum assembly
BVELS4_RS17305	COG4786	Flagellar basal body rod
BVELS4_RS17310	COG3418	PFAM FlgN family protein
BVELS4_RS17315	COG2747	anti-sigma28 factor FlgM
BVELS4_RS17325	COG1040	competence protein
BVELS4_RS17335	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BVELS4_RS17340	COG1307	EDD domain protein, DegV family
BVELS4_RS17345	COG2197	response regulator
BVELS4_RS17350	COG4585	Histidine kinase
BVELS4_RS17355	COG1739	Uncharacterized protein family UPF0029
BVELS4_RS17360	COG1316	TRANSCRIPTIONal
BVELS4_RS17365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVELS4_RS17370	COG0438	transferase activity, transferring glycosyl groups
BVELS4_RS17375	COG1215	transferase activity, transferring glycosyl groups
BVELS4_RS17380	COG3206	protein involved in exopolysaccharide biosynthesis
BVELS4_RS17385	COG3307	-O-antigen
BVELS4_RS17390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BVELS4_RS17395	COG0438	transferase activity, transferring glycosyl groups
BVELS4_RS17395	COG0297	glycogen (starch) synthase activity
BVELS4_RS17400	COG2244	polysaccharide biosynthetic process
BVELS4_RS17410	COG2247	cell wall binding repeat
BVELS4_RS17410	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVELS4_RS17415	COG2385	sporulation resulting in formation of a cellular spore
BVELS4_RS17415	COG2247	cell wall binding repeat
BVELS4_RS17425	COG1316	TRANSCRIPTIONal
BVELS4_RS17430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVELS4_RS17435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVELS4_RS17440	COG1134	teichoic acid transport
BVELS4_RS17445	COG1682	transport, permease protein
BVELS4_RS17450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BVELS4_RS17455	COG0438	transferase activity, transferring glycosyl groups
BVELS4_RS17460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BVELS4_RS17465	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BVELS4_RS17470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BVELS4_RS17475	COG4193	domain, Protein
BVELS4_RS17480	COG1482	cell wall glycoprotein biosynthetic process
BVELS4_RS17485	COG0697	spore germination
BVELS4_RS17490	COG0814	amino acid
BVELS4_RS17500	COG1215	transferase activity, transferring glycosyl groups
BVELS4_RS17505	COG2814	Major facilitator Superfamily
BVELS4_RS17510	COG1316	TRANSCRIPTIONal
BVELS4_RS17515	COG0561	phosphatase activity
BVELS4_RS17525	COG0791	NLP P60 protein
BVELS4_RS17535	COG2843	Capsule synthesis protein
BVELS4_RS17545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BVELS4_RS17550	COG0697	spore germination
BVELS4_RS17555	COG0814	amino acid
BVELS4_RS17565	COG1609	Transcriptional regulator
BVELS4_RS17570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVELS4_RS17580	COG1129	ABC transporter
BVELS4_RS17585	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVELS4_RS17590	COG1879	ABC-type sugar transport system periplasmic component
BVELS4_RS17595	COG3103	Sh3 type 3 domain protein
BVELS4_RS17600	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVELS4_RS17605	COG3527	Alpha-acetolactate decarboxylase
BVELS4_RS17610	COG0028	Belongs to the TPP enzyme family
BVELS4_RS17615	COG0583	DNA-binding transcription factor activity
BVELS4_RS17620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVELS4_RS17635	COG5337	Spore coat protein CotH
BVELS4_RS17645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVELS4_RS17655	COG0405	Gamma-glutamyltransferase
BVELS4_RS17660	COG1522	sequence-specific DNA binding
BVELS4_RS17665	COG2059	Chromate
BVELS4_RS17670	COG2059	Chromate
BVELS4_RS17700	COG3878	Protein conserved in bacteria
BVELS4_RS17705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BVELS4_RS17710	COG4464	protein tyrosine phosphatase activity
BVELS4_RS17715	COG0489	protein tyrosine kinase activity
BVELS4_RS17720	COG3944	biosynthesis protein
BVELS4_RS17730	COG4715	Zinc finger, swim domain protein
BVELS4_RS17735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVELS4_RS17740	COG0561	phosphatase activity
BVELS4_RS17745	COG1349	DNA-binding transcription factor activity
BVELS4_RS17750	COG0629	single-stranded DNA binding
BVELS4_RS17775	COG0457	Tetratricopeptide repeat
BVELS4_RS17780	COG4786	Flagellar basal body rod
BVELS4_RS17785	COG4786	Flagellar basal body rod
BVELS4_RS17790	COG1077	Cell shape determining protein MreB Mrl
BVELS4_RS17795	COG1609	Transcriptional regulator
BVELS4_RS17800	COG1846	Transcriptional regulator
BVELS4_RS17805	COG2814	Major facilitator Superfamily
BVELS4_RS17810	COG1953	Uracil, thiamine, allantoin
BVELS4_RS17815	COG0477	Major facilitator Superfamily
BVELS4_RS17820	COG1335	isochorismatase
BVELS4_RS17825	COG0004	ammonium transporteR
BVELS4_RS17830	COG0347	Belongs to the P(II) protein family
BVELS4_RS17835	COG0772	Belongs to the SEDS family
BVELS4_RS17840	COG0671	phosphoesterase, PA-phosphatase related
BVELS4_RS17850	COG0739	heme binding
BVELS4_RS17855	COG1247	-acetyltransferase
BVELS4_RS17870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVELS4_RS17880	COG0726	polysaccharide deacetylase
BVELS4_RS17885	COG1959	2 iron, 2 sulfur cluster binding
BVELS4_RS17900	COG0831	urea catabolic process
BVELS4_RS17905	COG3237	CsbD-like
BVELS4_RS17910	COG1994	Peptidase M50
BVELS4_RS17915	COG0457	Tetratricopeptide repeat
BVELS4_RS17925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BVELS4_RS17935	COG2304	oxidoreductase activity
BVELS4_RS17940	COG2304	oxidoreductase activity
BVELS4_RS17945	COG2385	sporulation resulting in formation of a cellular spore
BVELS4_RS17950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVELS4_RS17960	COG4836	Membrane
BVELS4_RS18030	COG0698	ribose 5-phosphate isomerase
BVELS4_RS18035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVELS4_RS18045	COG0009	L-threonylcarbamoyladenylate synthase
BVELS4_RS18050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BVELS4_RS18070	COG2890	protein-(glutamine-N5) methyltransferase activity
BVELS4_RS18075	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BVELS4_RS18080	COG0346	lactoylglutathione lyase activity
BVELS4_RS18085	COG0789	Transcriptional regulator
BVELS4_RS18090	COG0679	Auxin Efflux Carrier
BVELS4_RS18095	COG0281	malic enzyme
BVELS4_RS18110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BVELS4_RS18115	COG1494	fructose-1,6-bisphosphatase
BVELS4_RS18120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVELS4_RS18130	COG0191	fructose-bisphosphate aldolase activity
BVELS4_RS18135	COG2204	response regulator
BVELS4_RS18140	COG4821	SIS domain
BVELS4_RS18155	COG2181	nitrate reductase activity
BVELS4_RS18155	COG0247	lactate metabolic process
BVELS4_RS18160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVELS4_RS18175	COG1132	(ABC) transporter
BVELS4_RS18180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVELS4_RS18190	COG2181	nitrate reductase activity
BVELS4_RS18195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BVELS4_RS18200	COG1140	nitrate reductase beta subunit
BVELS4_RS18205	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BVELS4_RS18210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVELS4_RS18220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVELS4_RS18225	COG2223	nitrite transmembrane transporter activity
BVELS4_RS18235	COG4506	Protein conserved in bacteria
BVELS4_RS18245	COG3391	amine dehydrogenase activity
BVELS4_RS18250	COG3391	amine dehydrogenase activity
BVELS4_RS18255	COG0457	Tetratricopeptide repeat
BVELS4_RS18300	COG0010	Belongs to the arginase family
BVELS4_RS18305	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BVELS4_RS18310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVELS4_RS18325	COG1994	Peptidase M50
BVELS4_RS18330	COG1942	4-Oxalocrotonate Tautomerase
BVELS4_RS18335	COG1846	Transcriptional regulator
BVELS4_RS18340	COG0531	amino acid
BVELS4_RS18345	COG3465	dGTPase activity
BVELS4_RS18350	COG1078	dGTPase activity
BVELS4_RS18365	COG1695	Transcriptional regulator
BVELS4_RS18375	COG1131	(ABC) transporter
BVELS4_RS18380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BVELS4_RS18410	COG0583	DNA-binding transcription factor activity
BVELS4_RS18415	COG2855	membrane
BVELS4_RS18420	COG0280	phosphate acetyltransferase
BVELS4_RS18430	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS18435	COG0436	Aminotransferase
BVELS4_RS18465	COG2814	Major facilitator Superfamily
BVELS4_RS18470	COG2814	Major facilitator Superfamily
BVELS4_RS18475	COG0833	amino acid
BVELS4_RS18480	COG4187	Peptidase family M20/M25/M40
BVELS4_RS18485	COG1012	belongs to the aldehyde dehydrogenase family
BVELS4_RS18490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVELS4_RS18495	COG2205	protein histidine kinase activity
BVELS4_RS18500	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS18515	COG1131	(ABC) transporter
BVELS4_RS18520	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BVELS4_RS18525	COG1091	dTDP-4-dehydrorhamnose reductase activity
BVELS4_RS18530	COG1088	dTDP-glucose 4,6-dehydratase activity
BVELS4_RS18535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BVELS4_RS18540	COG3980	spore coat polysaccharide biosynthesis protein
BVELS4_RS18545	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BVELS4_RS18550	COG2089	acid synthase
BVELS4_RS18555	COG0456	acetyltransferase
BVELS4_RS18560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVELS4_RS18565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BVELS4_RS18570	COG0463	Glycosyl transferase, family 2
BVELS4_RS18580	COG2363	Small membrane protein
BVELS4_RS18585	COG2233	PERMEase
BVELS4_RS18600	COG1216	Glycosyl transferase, family 2
BVELS4_RS18615	COG1695	Transcriptional regulator
BVELS4_RS18620	COG0351	phosphomethylpyrimidine kinase
BVELS4_RS18630	COG1621	beta-fructofuranosidase activity
BVELS4_RS18635	COG1263	PTS System
BVELS4_RS18635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVELS4_RS18640	COG3711	transcriptional antiterminator
BVELS4_RS18650	COG1404	Belongs to the peptidase S8 family
BVELS4_RS18655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVELS4_RS18665	COG0778	Nitroreductase
BVELS4_RS18670	COG0772	Belongs to the SEDS family
BVELS4_RS18675	COG0454	-acetyltransferase
BVELS4_RS18695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BVELS4_RS18700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BVELS4_RS18705	COG2261	transglycosylase associated protein
BVELS4_RS18710	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BVELS4_RS18715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BVELS4_RS18720	COG2246	polysaccharide biosynthetic process
BVELS4_RS18725	COG1309	transcriptional regulator
BVELS4_RS18745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BVELS4_RS18750	COG2837	iron assimilation
BVELS4_RS18755	COG2822	iron ion transport
BVELS4_RS18770	COG0583	DNA-binding transcription factor activity
BVELS4_RS18780	COG1346	cytolysis
BVELS4_RS18785	COG4895	conserved protein (DUF2196)
BVELS4_RS18790	COG0789	Transcriptional regulator
BVELS4_RS18795	COG5504	Zn-dependent protease
BVELS4_RS18800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVELS4_RS18805	COG0346	lactoylglutathione lyase activity
BVELS4_RS18810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVELS4_RS18815	COG1404	Belongs to the peptidase S8 family
BVELS4_RS18820	COG1442	glycosyl transferase family 8
BVELS4_RS18825	COG2357	RelA SpoT domain protein
BVELS4_RS18830	COG1575	Belongs to the MenA family. Type 1 subfamily
BVELS4_RS18845	COG1696	Membrane protein involved in D-alanine export
BVELS4_RS18855	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BVELS4_RS18860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVELS4_RS18865	COG1486	melibiose metabolic process
BVELS4_RS18870	COG1447	Phosphotransferase system cellobiose-specific component IIA
BVELS4_RS18875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVELS4_RS18880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVELS4_RS18885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVELS4_RS18885	COG3711	transcriptional antiterminator
BVELS4_RS18895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVELS4_RS18900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVELS4_RS18910	COG0640	Transcriptional regulator
BVELS4_RS18915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVELS4_RS18920	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVELS4_RS18925	COG1447	Phosphotransferase system cellobiose-specific component IIA
BVELS4_RS18930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVELS4_RS18935	COG2723	6-phospho-beta-galactosidase activity
BVELS4_RS18940	COG1940	carbohydrate kinase activity
BVELS4_RS18945	COG1482	cell wall glycoprotein biosynthetic process
BVELS4_RS18955	COG0753	catalase activity
BVELS4_RS18960	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BVELS4_RS18965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BVELS4_RS18970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVELS4_RS18975	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BVELS4_RS18980	COG4988	ABC transporter
BVELS4_RS18985	COG1294	oxidase, subunit
BVELS4_RS18990	COG1271	oxidase subunit
BVELS4_RS18995	COG3493	citrate carrier protein
BVELS4_RS19000	COG0726	polysaccharide deacetylase
BVELS4_RS19005	COG3842	ATPase activity
BVELS4_RS19010	COG2508	Transcriptional regulator
BVELS4_RS19015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVELS4_RS19025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVELS4_RS19040	COG4894	glucomannan catabolic process
BVELS4_RS19045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BVELS4_RS19050	COG0500	methyltransferase
BVELS4_RS19055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVELS4_RS19070	COG0753	catalase activity
BVELS4_RS19070	COG0693	protein deglycase activity
BVELS4_RS19075	COG2851	Citrate transporter
BVELS4_RS19080	COG2273	Hydrolase Family 16
BVELS4_RS19085	COG3711	transcriptional antiterminator
BVELS4_RS19090	COG2270	Major facilitator Superfamily
BVELS4_RS19095	COG0513	Belongs to the DEAD box helicase family
BVELS4_RS19175	COG3209	COG3209 Rhs family protein
BVELS4_RS19185	COG0697	spore germination
BVELS4_RS19190	COG0589	response to stress
BVELS4_RS19195	COG2723	6-phospho-beta-galactosidase activity
BVELS4_RS19200	COG1263	PTS System
BVELS4_RS19200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVELS4_RS19200	COG2190	(PTS) system
BVELS4_RS19215	COG3507	Belongs to the glycosyl hydrolase 43 family
BVELS4_RS19240	COG0010	Belongs to the arginase family
BVELS4_RS19245	COG0833	amino acid
BVELS4_RS19255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVELS4_RS19265	COG2390	Transcriptional regulator
BVELS4_RS19270	COG0561	phosphatase activity
BVELS4_RS19300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVELS4_RS19305	COG5294	Protein conserved in bacteria
BVELS4_RS19310	COG0577	efflux transmembrane transporter activity
BVELS4_RS19315	COG1136	(ABC) transporter
BVELS4_RS19320	COG2205	protein histidine kinase activity
BVELS4_RS19325	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS19330	COG2205	protein histidine kinase activity
BVELS4_RS19335	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS19360	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS19390	COG1082	Xylose isomerase domain protein TIM barrel
BVELS4_RS19400	COG2814	Major facilitator Superfamily
BVELS4_RS19430	COG1349	DNA-binding transcription factor activity
BVELS4_RS19435	COG0667	Aldo Keto reductase
BVELS4_RS19440	COG2814	Major facilitator Superfamily
BVELS4_RS19455	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS19460	COG2197	response regulator
BVELS4_RS19465	COG4585	Histidine kinase
BVELS4_RS19470	COG3239	Fatty acid desaturase
BVELS4_RS19475	COG1309	transcriptional regulator
BVELS4_RS19480	COG1012	belongs to the aldehyde dehydrogenase family
BVELS4_RS19485	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVELS4_RS19495	COG0640	Transcriptional regulator
BVELS4_RS19500	COG2814	Major facilitator Superfamily
BVELS4_RS19505	COG1714	RDD family
BVELS4_RS19515	COG0501	Belongs to the peptidase M48B family
BVELS4_RS19520	COG1715	Restriction endonuclease
BVELS4_RS19525	COG0450	alkyl hydroperoxide reductase
BVELS4_RS19530	COG3634	alkyl hydroperoxide reductase activity
BVELS4_RS19535	COG3177	Filamentation induced by cAMP protein fic
BVELS4_RS19540	COG1113	amino acid transport
BVELS4_RS19550	COG2080	2 iron, 2 sulfur cluster binding
BVELS4_RS19565	COG2068	MobA-Related Protein
BVELS4_RS19570	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BVELS4_RS19590	COG0270	DNA (cytosine-5-)-methyltransferase activity
BVELS4_RS19635	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BVELS4_RS19640	COG0667	Aldo Keto reductase
BVELS4_RS19645	COG0456	acetyltransferase
BVELS4_RS19650	COG0457	Tetratricopeptide repeat
BVELS4_RS19655	COG0010	Belongs to the arginase family
BVELS4_RS19660	COG0833	amino acid
BVELS4_RS19665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVELS4_RS19670	COG5658	integral membrane protein
BVELS4_RS19675	COG0640	Transcriptional regulator
BVELS4_RS19680	COG3829	transcription factor binding
BVELS4_RS19690	COG0488	(ABC) transporter
BVELS4_RS19705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVELS4_RS19710	COG3850	Histidine kinase
BVELS4_RS19710	COG5002	protein histidine kinase activity
BVELS4_RS19715	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS19720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVELS4_RS19725	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BVELS4_RS19730	COG4853	Protein conserved in bacteria
BVELS4_RS19735	COG4863	YycH protein
BVELS4_RS19740	COG5002	protein histidine kinase activity
BVELS4_RS19745	COG0745	RESPONSE REGULATOR receiver
BVELS4_RS19775	COG0346	lactoylglutathione lyase activity
BVELS4_RS19780	COG0305	Participates in initiation and elongation during chromosome replication
BVELS4_RS19795	COG3093	addiction module antidote protein HigA
BVELS4_RS19800	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BVELS4_RS19815	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BVELS4_RS19820	COG0438	transferase activity, transferring glycosyl groups
BVELS4_RS19840	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BVELS4_RS19845	COG4241	membrane
BVELS4_RS19855	COG5577	PFAM Coat F domain
BVELS4_RS19860	COG1733	regulation of RNA biosynthetic process
BVELS4_RS19870	COG0697	spore germination
BVELS4_RS19875	COG1621	beta-fructofuranosidase activity
BVELS4_RS19880	COG1621	beta-fructofuranosidase activity
BVELS4_RS19885	COG1802	Transcriptional regulator
BVELS4_RS19890	COG2318	DinB family
BVELS4_RS19895	COG2211	Major facilitator Superfamily
BVELS4_RS19900	COG0583	DNA-binding transcription factor activity
BVELS4_RS19910	COG2814	Major facilitator Superfamily
BVELS4_RS19915	COG0583	DNA-binding transcription factor activity
BVELS4_RS19925	COG0778	Nitroreductase
BVELS4_RS19930	COG1846	Transcriptional regulator
BVELS4_RS19935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVELS4_RS19940	COG1846	Transcriptional regulator
BVELS4_RS19945	COG2153	protein acetylation
BVELS4_RS19955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVELS4_RS19960	COG0583	DNA-binding transcription factor activity
BVELS4_RS19965	COG1028	Short-chain dehydrogenase reductase Sdr
BVELS4_RS19970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVELS4_RS19975	COG0697	spore germination
BVELS4_RS19980	COG1331	Highly conserved protein containing a thioredoxin domain
BVELS4_RS19985	COG1266	CAAX protease self-immunity
BVELS4_RS19990	COG0477	Major facilitator Superfamily
BVELS4_RS19990	COG2814	Major facilitator Superfamily
BVELS4_RS19995	COG0346	lactoylglutathione lyase activity
BVELS4_RS20000	COG1609	Transcriptional regulator
BVELS4_RS20005	COG0708	Exodeoxyribonuclease III
BVELS4_RS20010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVELS4_RS20015	COG2169	Transcriptional regulator
BVELS4_RS20025	COG0629	single-stranded DNA binding
BVELS4_RS20035	COG0012	GTP binding
BVELS4_RS20040	COG0243	molybdopterin cofactor binding
BVELS4_RS20045	COG4481	Protein conserved in bacteria
BVELS4_RS20050	COG3949	Membrane
BVELS4_RS20065	COG1475	DNA binding
BVELS4_RS20070	COG1192	Involved in chromosome partitioning
BVELS4_RS20095	COG1847	R3H domain protein
BVELS4_RS20100	COG0706	membrane insertase activity