locus-tag	class	description
CLI97_RS00005	COG0270	DNA (cytosine-5-)-methyltransferase activity
CLI97_RS00020	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CLI97_RS00025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLI97_RS00040	COG3584	3D domain protein
CLI97_RS00045	COG0587	DNA-directed DNA polymerase activity
CLI97_RS00050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLI97_RS00055	COG0358	DNA primase activity
CLI97_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
CLI97_RS00070	COG2887	Belongs to the helicase family. UvrD subfamily
CLI97_RS00100	COG3420	alginic acid biosynthetic process
CLI97_RS00100	COG5434	Belongs to the glycosyl hydrolase 28 family
CLI97_RS00105	COG4195	phage-related replication protein
CLI97_RS00130	COG2135	peptidase activity
CLI97_RS00135	COG1793	dna ligase
CLI97_RS00180	COG3655	Transcriptional regulator
CLI97_RS00290	COG3655	Transcriptional regulator
CLI97_RS00410	COG0776	regulation of translation
CLI97_RS00540	COG0582	viral genome integration into host DNA
CLI97_RS00560	COG0739	heme binding
CLI97_RS00560	COG1196	nuclear chromosome segregation
CLI97_RS00560	COG0741	lytic transglycosylase activity
CLI97_RS00580	COG5434	Belongs to the glycosyl hydrolase 28 family
CLI97_RS00585	COG3409	Peptidoglycan-binding domain 1 protein
CLI97_RS00585	COG5632	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS00610	COG0457	Tetratricopeptide repeat
CLI97_RS00615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLI97_RS00660	COG5444	nuclease activity
CLI97_RS00670	COG4282	regulation of fungal-type cell wall biogenesis
CLI97_RS00675	COG1525	nuclease
CLI97_RS00680	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLI97_RS00685	COG1509	lysine 2,3-aminomutase activity
CLI97_RS00690	COG0456	acetyltransferase
CLI97_RS00695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLI97_RS00700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLI97_RS00705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CLI97_RS00710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLI97_RS00720	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CLI97_RS00730	COG0456	acetyltransferase
CLI97_RS00735	COG0463	Glycosyl transferase, family 2
CLI97_RS00750	COG4641	Protein conserved in bacteria
CLI97_RS00790	COG1388	LysM domain
CLI97_RS00795	COG0457	Tetratricopeptide repeat
CLI97_RS00820	COG5444	nuclease activity
CLI97_RS00825	COG4282	regulation of fungal-type cell wall biogenesis
CLI97_RS00830	COG1525	nuclease
CLI97_RS00865	COG1846	Transcriptional regulator
CLI97_RS00870	COG4698	Protein conserved in bacteria
CLI97_RS00875	COG2755	lipolytic protein G-D-S-L family
CLI97_RS00880	COG1999	signal sequence binding
CLI97_RS00890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLI97_RS00895	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLI97_RS00900	COG1272	protein, Hemolysin III
CLI97_RS00905	COG0204	Acyl-transferase
CLI97_RS00910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLI97_RS00925	COG2136	Putative SAM-dependent methyltransferase
CLI97_RS00925	COG2521	methyltransferase
CLI97_RS00940	COG1413	lyase activity
CLI97_RS00945	COG1418	mRNA catabolic process
CLI97_RS00950	COG0386	Belongs to the glutathione peroxidase family
CLI97_RS00960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLI97_RS00965	COG1278	Cold shock
CLI97_RS00985	COG0328	RNA-DNA hybrid ribonuclease activity
CLI97_RS00990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CLI97_RS00995	COG0328	RNA-DNA hybrid ribonuclease activity
CLI97_RS01005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI97_RS01020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CLI97_RS01030	COG1755	Isoprenylcysteine carboxyl methyltransferase
CLI97_RS01035	COG3424	synthase
CLI97_RS01060	COG1335	isochorismatase
CLI97_RS01070	COG2233	PERMEase
CLI97_RS01080	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CLI97_RS01085	COG1199	ATP-dependent helicase activity
CLI97_RS01100	COG0116	Belongs to the methyltransferase superfamily
CLI97_RS01125	COG3359	exonuclease
CLI97_RS01130	COG1205	dead DEAH box helicase
CLI97_RS01130	COG1111	helicase
CLI97_RS01135	COG2190	(PTS) system
CLI97_RS01140	COG0071	Belongs to the small heat shock protein (HSP20) family
CLI97_RS01180	COG4499	WXG100 protein secretion system (Wss), protein YukC
CLI97_RS01180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLI97_RS01190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLI97_RS01195	COG3935	DnaD domain protein
CLI97_RS01205	COG0436	Aminotransferase
CLI97_RS01210	COG5353	protein conserved in bacteria
CLI97_RS01220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLI97_RS01220	COG1199	ATP-dependent helicase activity
CLI97_RS01250	COG0438	transferase activity, transferring glycosyl groups
CLI97_RS01255	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLI97_RS01270	COG1694	Mazg nucleotide pyrophosphohydrolase
CLI97_RS01275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLI97_RS01280	COG2140	Oxalate decarboxylase
CLI97_RS01290	COG4347	Protein of unknown function (DUF1405)
CLI97_RS01295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CLI97_RS01295	COG2010	Cytochrome c
CLI97_RS01300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CLI97_RS01305	COG0723	plastoquinol--plastocyanin reductase activity
CLI97_RS01320	COG0457	Tetratricopeptide repeat
CLI97_RS01330	COG0287	Prephenate dehydrogenase
CLI97_RS01365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLI97_RS01370	COG4401	Chorismate mutase type I
CLI97_RS01385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLI97_RS01390	COG0105	UTP biosynthetic process
CLI97_RS01395	COG0142	geranyltranstransferase activity
CLI97_RS01405	COG0142	geranyltranstransferase activity
CLI97_RS01420	COG0776	regulation of translation
CLI97_RS01425	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CLI97_RS01465	COG0539	negative regulation of cytoplasmic translation
CLI97_RS01480	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CLI97_RS01485	COG2959	enzyme of heme biosynthesis
CLI97_RS01490	COG3773	Cell wall hydrolase
CLI97_RS01490	COG3409	Peptidoglycan-binding domain 1 protein
CLI97_RS01495	COG2339	peptidase activity
CLI97_RS01500	COG0492	ferredoxin-NADP+ reductase activity
CLI97_RS01505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLI97_RS01510	COG4862	establishment of competence for transformation
CLI97_RS01515	COG1408	metallophosphoesterase
CLI97_RS01525	COG1388	LysM domain
CLI97_RS01530	COG1266	CAAX protease self-immunity
CLI97_RS01535	COG0514	ATP-dependent DNA helicase (RecQ)
CLI97_RS01540	COG4955	Helix-turn-helix domain
CLI97_RS01545	COG1141	Ferredoxin
CLI97_RS01550	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CLI97_RS01555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLI97_RS01565	COG1595	DNA-templated transcription, initiation
CLI97_RS01570	COG5002	protein histidine kinase activity
CLI97_RS01575	COG0745	RESPONSE REGULATOR receiver
CLI97_RS01580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLI97_RS01585	COG1333	cytochrome c biogenesis protein
CLI97_RS01590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS01595	COG1187	pseudouridine synthase activity
CLI97_RS01600	COG0700	Nucleoside recognition
CLI97_RS01605	COG2715	membrane protein required for spore maturation
CLI97_RS01610	COG1686	Belongs to the peptidase S11 family
CLI97_RS01635	COG1547	Domain of unknown function (DUF309)
CLI97_RS01645	COG0456	acetyltransferase
CLI97_RS01660	COG0307	riboflavin synthase, alpha
CLI97_RS01665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLI97_RS01665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLI97_RS01675	COG0681	Belongs to the peptidase S26 family
CLI97_RS01685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLI97_RS01690	COG4086	secreted protein
CLI97_RS01695	COG0019	diaminopimelate decarboxylase activity
CLI97_RS01700	COG0697	spore germination
CLI97_RS01715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLI97_RS01735	COG1191	sigma factor activity
CLI97_RS01745	COG1366	Belongs to the anti-sigma-factor antagonist family
CLI97_RS01750	COG1686	Belongs to the peptidase S11 family
CLI97_RS01755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CLI97_RS01760	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLI97_RS01765	COG4974	Belongs to the 'phage' integrase family
CLI97_RS01775	COG0735	belongs to the Fur family
CLI97_RS01780	COG1300	Membrane
CLI97_RS01795	COG0281	malic enzyme
CLI97_RS01800	COG1757	Na H antiporter
CLI97_RS01805	COG1027	Aspartate ammonia-lyase
CLI97_RS01810	COG0252	asparaginase activity
CLI97_RS01815	COG1396	sequence-specific DNA binding
CLI97_RS01820	COG1379	DNA repair
CLI97_RS01825	COG0494	nUDIX hydrolase
CLI97_RS01835	COG0667	Aldo Keto reductase
CLI97_RS01845	COG1073	alpha beta
CLI97_RS01855	COG4918	Iron-sulphur cluster biosynthesis
CLI97_RS01860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CLI97_RS01860	COG0456	acetyltransferase
CLI97_RS01865	COG2329	Antibiotic biosynthesis monooxygenase
CLI97_RS01870	COG0456	acetyltransferase
CLI97_RS01875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLI97_RS01890	COG0628	permease
CLI97_RS01900	COG0346	lactoylglutathione lyase activity
CLI97_RS01910	COG3048	D-serine ammonia-lyase activity
CLI97_RS01915	COG0300	oxidoreductase activity
CLI97_RS01920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI97_RS01925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLI97_RS01930	COG1024	Enoyl-CoA hydratase
CLI97_RS01935	COG3425	synthase
CLI97_RS01940	COG2124	cytochrome p450
CLI97_RS01945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS01945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS01945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI97_RS01945	COG3321	synthase
CLI97_RS01950	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS01950	COG3321	synthase
CLI97_RS01950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS01950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI97_RS01950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS01955	COG0300	oxidoreductase activity
CLI97_RS01955	COG3321	synthase
CLI97_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS01955	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS01955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS01960	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS01960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS01960	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS01960	COG0300	oxidoreductase activity
CLI97_RS01960	COG3321	synthase
CLI97_RS01965	COG3321	synthase
CLI97_RS01965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI97_RS01965	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS01965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS01970	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS01970	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS01970	COG0300	oxidoreductase activity
CLI97_RS01970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS01970	COG3321	synthase
CLI97_RS01975	COG3321	synthase
CLI97_RS01975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI97_RS01975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS01985	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS02000	COG2070	2-Nitropropane dioxygenase
CLI97_RS02000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLI97_RS02010	COG0250	Participates in transcription elongation, termination and antitermination
CLI97_RS02035	COG0596	Alpha beta hydrolase
CLI97_RS02050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLI97_RS02055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CLI97_RS02070	COG0706	membrane insertase activity
CLI97_RS02075	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLI97_RS02080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLI97_RS02085	COG0346	lactoylglutathione lyase activity
CLI97_RS02090	COG1376	ErfK ybiS ycfS ynhG family protein
CLI97_RS02095	COG4129	membrane
CLI97_RS02100	COG1126	abc transporter atp-binding protein
CLI97_RS02105	COG0765	amino acid transport
CLI97_RS02110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI97_RS02120	COG1597	lipid kinase activity
CLI97_RS02125	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLI97_RS02130	COG0022	dehydrogenase e1 component
CLI97_RS02135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CLI97_RS02140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI97_RS02145	COG3426	butyrate kinase activity
CLI97_RS02150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLI97_RS02155	COG0280	phosphate acetyltransferase
CLI97_RS02160	COG3829	transcription factor binding
CLI97_RS02160	COG3290	protein histidine kinase activity
CLI97_RS02170	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CLI97_RS02175	COG2079	MmgE PrpD family protein
CLI97_RS02180	COG0372	Belongs to the citrate synthase family
CLI97_RS02185	COG1960	acyl-CoA dehydrogenase activity
CLI97_RS02190	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLI97_RS02195	COG0183	Belongs to the thiolase family
CLI97_RS02200	COG0584	glycerophosphoryl diester phosphodiesterase
CLI97_RS02205	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS02225	COG1902	pentaerythritol trinitrate reductase activity
CLI97_RS02240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLI97_RS02250	COG4974	Belongs to the 'phage' integrase family
CLI97_RS02280	COG5632	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS02280	COG3409	Peptidoglycan-binding domain 1 protein
CLI97_RS02280	COG1388	LysM domain
CLI97_RS02305	COG5434	Belongs to the glycosyl hydrolase 28 family
CLI97_RS02315	COG1705	Flagellar rod assembly protein muramidase FlgJ
CLI97_RS02410	COG0582	viral genome integration into host DNA
CLI97_RS02455	COG1793	dna ligase
CLI97_RS02500	COG3584	3D domain protein
CLI97_RS02500	COG3583	domain protein
CLI97_RS02505	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CLI97_RS02515	COG0756	dUTP diphosphatase activity
CLI97_RS02520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI97_RS02530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI97_RS02540	COG1780	Probably involved in ribonucleotide reductase function
CLI97_RS02580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLI97_RS02600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI97_RS02600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI97_RS02640	COG3655	Transcriptional regulator
CLI97_RS02670	COG1484	DNA-dependent DNA replication
CLI97_RS02710	COG0745	RESPONSE REGULATOR receiver
CLI97_RS02715	COG0750	zinc metalloprotease
CLI97_RS02720	COG0497	DNA recombination
CLI97_RS02730	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CLI97_RS02740	COG0142	geranyltranstransferase activity
CLI97_RS02750	COG1570	exodeoxyribonuclease VII activity
CLI97_RS02765	COG1302	Protein conserved in bacteria
CLI97_RS02770	COG0439	Biotin carboxylase
CLI97_RS02775	COG0511	ligase activity, forming carbon-carbon bonds
CLI97_RS02815	COG3854	ATPases associated with a variety of cellular activities
CLI97_RS02830	COG0006	proline dipeptidase activity
CLI97_RS02840	COG3872	metal-dependent enzyme
CLI97_RS02850	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLI97_RS02865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLI97_RS02885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLI97_RS02900	COG1396	sequence-specific DNA binding
CLI97_RS02910	COG0681	Belongs to the peptidase S26 family
CLI97_RS02935	COG4940	Competence protein ComGF
CLI97_RS02945	COG4970	Tfp pilus assembly protein FimT
CLI97_RS02950	COG4537	Required for transformation and DNA binding
CLI97_RS02955	COG1459	type II secretion system
CLI97_RS02960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLI97_RS02965	COG0598	Magnesium transport protein CorA
CLI97_RS02970	COG1253	flavin adenine dinucleotide binding
CLI97_RS02975	COG1366	Belongs to the anti-sigma-factor antagonist family
CLI97_RS02985	COG1393	Belongs to the ArsC family
CLI97_RS02995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI97_RS03005	COG0011	TIGRFAM Protein of
CLI97_RS03015	COG2866	Carboxypeptidase
CLI97_RS03020	COG1940	carbohydrate kinase activity
CLI97_RS03025	COG4483	Protein conserved in bacteria
CLI97_RS03030	COG1757	Na H antiporter
CLI97_RS03040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLI97_RS03055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLI97_RS03060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLI97_RS03065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLI97_RS03070	COG0581	inorganic phosphate transmembrane transporter activity
CLI97_RS03075	COG0573	inorganic phosphate transmembrane transporter activity
CLI97_RS03080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLI97_RS03085	COG0768	penicillin binding
CLI97_RS03090	COG0477	Major facilitator Superfamily
CLI97_RS03095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLI97_RS03100	COG2839	Protein conserved in bacteria
CLI97_RS03105	COG5521	maltodextrose utilization protein MalA
CLI97_RS03110	COG1388	LysM domain
CLI97_RS03120	COG4709	membrane
CLI97_RS03125	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CLI97_RS03130	COG0735	belongs to the Fur family
CLI97_RS03135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLI97_RS03150	COG0513	Belongs to the DEAD box helicase family
CLI97_RS03165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLI97_RS03170	COG2384	SAM-dependent methyltransferase
CLI97_RS03175	COG2010	Cytochrome c
CLI97_RS03180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLI97_RS03185	COG0358	DNA primase activity
CLI97_RS03200	COG0517	IMP dehydrogenase activity
CLI97_RS03205	COG0751	glycine-tRNA ligase activity
CLI97_RS03225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLI97_RS03230	COG0295	cytidine deaminase activity
CLI97_RS03235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLI97_RS03245	COG1480	7TM receptor with intracellular HD hydrolase
CLI97_RS03250	COG1702	phosphate starvation-inducible protein PhoH
CLI97_RS03255	COG0561	phosphatase activity
CLI97_RS03270	COG4864	UPF0365 protein
CLI97_RS03275	COG1030	water channel activity
CLI97_RS03280	COG1610	YqeY-like protein
CLI97_RS03290	COG1283	sodium-dependent phosphate transmembrane transporter activity
CLI97_RS03295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLI97_RS03300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLI97_RS03330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLI97_RS03345	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS03360	COG1466	dna polymerase III delta subunit
CLI97_RS03370	COG2333	competence protein COMEC
CLI97_RS03370	COG0658	competence protein
CLI97_RS03375	COG2131	deaminase
CLI97_RS03380	COG1596	polysaccharide export
CLI97_RS03380	COG1555	photosystem II stabilization
CLI97_RS03385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLI97_RS03390	COG2226	methyltransferase
CLI97_RS03395	COG0799	negative regulation of ribosome biogenesis
CLI97_RS03400	COG1713	HD superfamily hydrolase involved in NAD metabolism
CLI97_RS03410	COG1534	Rna-binding protein
CLI97_RS03415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLI97_RS03420	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CLI97_RS03425	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CLI97_RS03435	COG2755	lipolytic protein G-D-S-L family
CLI97_RS03445	COG0398	Pfam SNARE associated Golgi protein
CLI97_RS03470	COG1794	racemase activity, acting on amino acids and derivatives
CLI97_RS03485	COG1733	regulation of RNA biosynthetic process
CLI97_RS03490	COG0656	L-ascorbic acid biosynthetic process
CLI97_RS03530	COG0563	adenylate kinase activity
CLI97_RS03540	COG2814	Major facilitator Superfamily
CLI97_RS03545	COG0456	acetyltransferase
CLI97_RS03550	COG2318	DinB family
CLI97_RS03560	COG0561	phosphatase activity
CLI97_RS03565	COG0561	phosphatase activity
CLI97_RS03575	COG1482	cell wall glycoprotein biosynthetic process
CLI97_RS03580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI97_RS03580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI97_RS03580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI97_RS03585	COG3711	transcriptional antiterminator
CLI97_RS03585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI97_RS03595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLI97_RS03600	COG0583	DNA-binding transcription factor activity
CLI97_RS03605	COG2814	Major facilitator Superfamily
CLI97_RS03610	COG2124	cytochrome p450
CLI97_RS03610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLI97_RS03615	COG1309	transcriptional regulator
CLI97_RS03620	COG2226	methyltransferase
CLI97_RS03635	COG2116	formate transmembrane transporter activity
CLI97_RS03640	COG5609	conserved protein (DUF2294)
CLI97_RS03645	COG3383	formate dehydrogenase (NAD+) activity
CLI97_RS03650	COG2427	Protein of unknown function (DUF1641)
CLI97_RS03665	COG0626	cystathionine gamma-synthase activity
CLI97_RS03670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLI97_RS03695	COG0768	penicillin binding
CLI97_RS03710	COG0826	peptidase U32
CLI97_RS03715	COG0826	peptidase U32
CLI97_RS03720	COG4122	O-methyltransferase activity
CLI97_RS03725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLI97_RS03750	COG0628	permease
CLI97_RS03755	COG1126	abc transporter atp-binding protein
CLI97_RS03760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI97_RS03765	COG0765	amino acid transport
CLI97_RS03770	COG0765	amino acid transport
CLI97_RS03785	COG3881	PFAM PRC-barrel domain
CLI97_RS03790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLI97_RS03795	COG0457	Tetratricopeptide repeat
CLI97_RS03805	COG1104	cysteine desulfurase activity
CLI97_RS03810	COG1959	2 iron, 2 sulfur cluster binding
CLI97_RS03815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLI97_RS03820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLI97_RS03845	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS03845	COG3103	Sh3 type 3 domain protein
CLI97_RS03845	COG4991	sh3 domain protein
CLI97_RS03855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLI97_RS03865	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CLI97_RS03865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLI97_RS03870	COG5416	Lipopolysaccharide assembly protein A domain
CLI97_RS03875	COG0490	domain, Protein
CLI97_RS03880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI97_RS03880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI97_RS03890	COG2244	polysaccharide biosynthetic process
CLI97_RS03895	COG2323	membrane
CLI97_RS03905	COG1862	Preprotein translocase
CLI97_RS03950	COG1388	LysM domain
CLI97_RS03960	COG0157	Belongs to the NadC ModD family
CLI97_RS03965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CLI97_RS03970	COG1104	cysteine desulfurase activity
CLI97_RS03975	COG1827	regulation of RNA biosynthetic process
CLI97_RS03980	COG0077	Prephenate dehydratase
CLI97_RS03995	COG3290	protein histidine kinase activity
CLI97_RS04000	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLI97_RS04005	COG2868	ribosomal protein
CLI97_RS04015	COG1994	Peptidase M50
CLI97_RS04020	COG0739	heme binding
CLI97_RS04025	COG2894	cell division
CLI97_RS04035	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CLI97_RS04045	COG1077	Cell shape determining protein MreB Mrl
CLI97_RS04065	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CLI97_RS04070	COG0285	dihydrofolate synthase activity
CLI97_RS04075	COG0525	valine-tRNA ligase activity
CLI97_RS04085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLI97_RS04090	COG1388	LysM domain
CLI97_RS04100	COG0113	porphobilinogen synthase activity
CLI97_RS04105	COG1587	Uroporphyrinogen-III synthase
CLI97_RS04115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLI97_RS04135	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLI97_RS04140	COG1067	ATP-dependent peptidase activity
CLI97_RS04140	COG0470	DNA polymerase III
CLI97_RS04155	COG0457	Tetratricopeptide repeat
CLI97_RS04155	COG1477	protein flavinylation
CLI97_RS04170	COG0473	3-isopropylmalate dehydrogenase activity
CLI97_RS04185	COG0440	acetolactate synthase activity
CLI97_RS04190	COG0028	Belongs to the TPP enzyme family
CLI97_RS04215	COG0622	Phosphoesterase
CLI97_RS04220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLI97_RS04230	COG5401	PFAM Sporulation and spore germination
CLI97_RS04240	COG1846	Transcriptional regulator
CLI97_RS04245	COG2197	response regulator
CLI97_RS04250	COG0824	Thioesterase
CLI97_RS04255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLI97_RS04260	COG1053	succinate dehydrogenase
CLI97_RS04265	COG2009	succinate dehydrogenase
CLI97_RS04270	COG1719	4-vinyl reductase, 4VR
CLI97_RS04275	COG0527	aspartate kinase activity
CLI97_RS04290	COG3118	belongs to the thioredoxin family
CLI97_RS04295	COG3534	alpha-L-arabinofuranosidase
CLI97_RS04300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CLI97_RS04305	COG2086	electron transfer activity
CLI97_RS04310	COG1024	Enoyl-CoA hydratase
CLI97_RS04315	COG1309	transcriptional regulator
CLI97_RS04320	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS04330	COG3766	membrane
CLI97_RS04340	COG1796	DNA polymerase
CLI97_RS04340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CLI97_RS04345	COG1286	toxin biosynthetic process
CLI97_RS04360	COG0072	phenylalanine-tRNA ligase activity
CLI97_RS04360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI97_RS04365	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLI97_RS04370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLI97_RS04380	COG3835	regulator
CLI97_RS04385	COG0277	FAD linked oxidase domain protein
CLI97_RS04390	COG0247	lactate metabolic process
CLI97_RS04395	COG1966	Carbon starvation protein
CLI97_RS04400	COG3534	alpha-L-arabinofuranosidase
CLI97_RS04405	COG0395	ABC-type sugar transport system, permease component
CLI97_RS04410	COG1175	transmembrane transport
CLI97_RS04415	COG1653	transport
CLI97_RS04425	COG0647	UMP catabolic process
CLI97_RS04430	COG0235	Class ii aldolase
CLI97_RS04435	COG1069	ribulokinase activity
CLI97_RS04440	COG2160	L-arabinose isomerase activity
CLI97_RS04445	COG3507	Belongs to the glycosyl hydrolase 43 family
CLI97_RS04450	COG1363	Peptidase, m42
CLI97_RS04460	COG3326	Membrane
CLI97_RS04465	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLI97_RS04475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLI97_RS04480	COG1346	cytolysis
CLI97_RS04485	COG1380	Effector of murein hydrolase LrgA
CLI97_RS04490	COG3279	Response regulator of the LytR AlgR family
CLI97_RS04495	COG3275	phosphorelay sensor kinase activity
CLI97_RS04500	COG1011	Hydrolase
CLI97_RS04515	COG0398	Pfam SNARE associated Golgi protein
CLI97_RS04520	COG1484	DNA-dependent DNA replication
CLI97_RS04525	COG3611	Membrane attachment protein
CLI97_RS04540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLI97_RS04545	COG1733	regulation of RNA biosynthetic process
CLI97_RS04550	COG2814	Major facilitator Superfamily
CLI97_RS04555	COG0656	L-ascorbic acid biosynthetic process
CLI97_RS04560	COG0237	dephospho-CoA kinase activity
CLI97_RS04565	COG1971	Probably functions as a manganese efflux pump
CLI97_RS04570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CLI97_RS04575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI97_RS04575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI97_RS04580	COG5002	protein histidine kinase activity
CLI97_RS04585	COG0745	RESPONSE REGULATOR receiver
CLI97_RS04595	COG0538	isocitrate dehydrogenase activity
CLI97_RS04600	COG0372	Belongs to the citrate synthase family
CLI97_RS04625	COG0628	permease
CLI97_RS04630	COG3030	protein affecting phage T7 exclusion by the F plasmid
CLI97_RS04635	COG0469	pyruvate kinase activity
CLI97_RS04655	COG0281	malic enzyme
CLI97_RS04660	COG0587	DNA-directed DNA polymerase activity
CLI97_RS04680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CLI97_RS04690	COG4109	DRTGG domain
CLI97_RS04700	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS04720	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLI97_RS04730	COG0827	DNA restriction-modification system
CLI97_RS04735	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLI97_RS04740	COG3874	Sporulation protein YtfJ
CLI97_RS04750	COG1714	RDD family
CLI97_RS04755	COG0616	signal peptide processing
CLI97_RS04760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLI97_RS04765	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CLI97_RS04770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLI97_RS04785	COG1104	cysteine desulfurase activity
CLI97_RS04790	COG1114	Component of the transport system for branched-chain amino acids
CLI97_RS04800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CLI97_RS04805	COG1309	transcriptional regulator
CLI97_RS04810	COG1956	GAF domain-containing protein
CLI97_RS04815	COG2199	diguanylate cyclase activity
CLI97_RS04815	COG2203	Gaf domain
CLI97_RS04830	COG4282	regulation of fungal-type cell wall biogenesis
CLI97_RS04880	COG1017	nitric oxide dioxygenase activity
CLI97_RS04880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLI97_RS04890	COG0693	protein deglycase activity
CLI97_RS04905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLI97_RS04910	COG1378	Sugar-specific transcriptional regulator TrmB
CLI97_RS04935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLI97_RS04940	COG0454	-acetyltransferase
CLI97_RS04945	COG0517	IMP dehydrogenase activity
CLI97_RS04950	COG0123	including yeast histone deacetylase and acetoin utilization protein
CLI97_RS04955	COG1360	Flagellar Motor Protein
CLI97_RS04960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLI97_RS04965	COG1609	Transcriptional regulator
CLI97_RS04970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CLI97_RS04970	COG1605	Chorismate mutase
CLI97_RS04975	COG3118	belongs to the thioredoxin family
CLI97_RS04980	COG4980	gas vesicle protein
CLI97_RS04985	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CLI97_RS04995	COG1674	ftsk spoiiie
CLI97_RS05000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI97_RS05010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS05020	COG1363	Peptidase, m42
CLI97_RS05025	COG5584	Small secreted protein
CLI97_RS05030	COG0281	malic enzyme
CLI97_RS05035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI97_RS05050	COG0510	thiamine kinase activity
CLI97_RS05055	COG1597	lipid kinase activity
CLI97_RS05065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CLI97_RS05070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLI97_RS05075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLI97_RS05080	COG2252	PERMEase
CLI97_RS05085	COG4473	ABC transporter
CLI97_RS05090	COG1131	(ABC) transporter
CLI97_RS05095	COG1349	DNA-binding transcription factor activity
CLI97_RS05100	COG1187	pseudouridine synthase activity
CLI97_RS05105	COG2244	polysaccharide biosynthetic process
CLI97_RS05110	COG2081	HI0933 family
CLI97_RS05115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLI97_RS05125	COG1609	Transcriptional regulator
CLI97_RS05130	COG1653	transport
CLI97_RS05135	COG1175	transmembrane transport
CLI97_RS05140	COG0395	ABC-type sugar transport system, permease component
CLI97_RS05145	COG1486	melibiose metabolic process
CLI97_RS05155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLI97_RS05170	COG1366	Belongs to the anti-sigma-factor antagonist family
CLI97_RS05170	COG2202	Pas domain
CLI97_RS05175	COG2814	Major facilitator Superfamily
CLI97_RS05180	COG5522	Integral membrane protein (intg_mem_TP0381)
CLI97_RS05185	COG0577	efflux transmembrane transporter activity
CLI97_RS05190	COG1136	(ABC) transporter
CLI97_RS05195	COG2205	protein histidine kinase activity
CLI97_RS05200	COG0745	RESPONSE REGULATOR receiver
CLI97_RS05205	COG0577	efflux transmembrane transporter activity
CLI97_RS05210	COG1136	(ABC) transporter
CLI97_RS05230	COG1131	(ABC) transporter
CLI97_RS05235	COG1725	Transcriptional regulator
CLI97_RS05245	COG1242	4 iron, 4 sulfur cluster binding
CLI97_RS05250	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CLI97_RS05260	COG0584	glycerophosphoryl diester phosphodiesterase
CLI97_RS05270	COG2267	carboxylic ester hydrolase activity
CLI97_RS05275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLI97_RS05280	COG1113	amino acid transport
CLI97_RS05285	COG0367	asparagine synthase
CLI97_RS05305	COG1506	peptidase
CLI97_RS05310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLI97_RS05315	COG1116	anion transmembrane transporter activity
CLI97_RS05320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLI97_RS05325	COG0494	nUDIX hydrolase
CLI97_RS05330	COG4824	toxin secretion phage lysis holin
CLI97_RS05335	COG0783	Belongs to the Dps family
CLI97_RS05360	COG0288	reversible hydration of carbon dioxide
CLI97_RS05370	COG1271	oxidase subunit
CLI97_RS05375	COG1294	oxidase, subunit
CLI97_RS05390	COG4948	Mandelate Racemase Muconate Lactonizing
CLI97_RS05400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CLI97_RS05405	COG0596	Alpha beta hydrolase
CLI97_RS05415	COG1169	isochorismate synthase
CLI97_RS05420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CLI97_RS05425	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CLI97_RS05550	COG3859	Proton-coupled thiamine transporter YuaJ
CLI97_RS05555	COG2268	Band 7 protein
CLI97_RS05560	COG1585	Membrane protein implicated in regulation of membrane protease activity
CLI97_RS05565	COG2318	DinB family
CLI97_RS05575	COG1454	alcohol dehydrogenase
CLI97_RS05580	COG1012	belongs to the aldehyde dehydrogenase family
CLI97_RS05585	COG1510	regulation of RNA biosynthetic process
CLI97_RS05595	COG0569	domain protein
CLI97_RS05600	COG1705	Flagellar rod assembly protein muramidase FlgJ
CLI97_RS05605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLI97_RS05605	COG1017	nitric oxide dioxygenase activity
CLI97_RS05625	COG0457	Tetratricopeptide repeat
CLI97_RS05650	COG0628	permease
CLI97_RS05655	COG0673	inositol 2-dehydrogenase activity
CLI97_RS05660	COG0693	protein deglycase activity
CLI97_RS05665	COG0840	transmembrane signaling receptor activity
CLI97_RS05670	COG0840	transmembrane signaling receptor activity
CLI97_RS05675	COG0840	transmembrane signaling receptor activity
CLI97_RS05680	COG0840	transmembrane signaling receptor activity
CLI97_RS05695	COG2070	2-Nitropropane dioxygenase
CLI97_RS05700	COG0432	Pfam Uncharacterised protein family UPF0047
CLI97_RS05705	COG0366	Alpha amylase catalytic
CLI97_RS05710	COG1253	flavin adenine dinucleotide binding
CLI97_RS05715	COG2738	Putative neutral zinc metallopeptidase
CLI97_RS05730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLI97_RS05755	COG1335	isochorismatase
CLI97_RS05765	COG1979	alcohol dehydrogenase
CLI97_RS05770	COG1979	alcohol dehydrogenase
CLI97_RS05775	COG2155	Conserved Protein
CLI97_RS05780	COG1098	S1 RNA binding domain
CLI97_RS05785	COG0436	Aminotransferase
CLI97_RS05790	COG1522	sequence-specific DNA binding
CLI97_RS05795	COG2267	carboxylic ester hydrolase activity
CLI97_RS05805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CLI97_RS05810	COG2205	protein histidine kinase activity
CLI97_RS05820	COG5018	Exonuclease
CLI97_RS05825	COG2814	Major facilitator Superfamily
CLI97_RS05830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLI97_RS05835	COG3011	Protein conserved in bacteria
CLI97_RS05845	COG3290	protein histidine kinase activity
CLI97_RS05850	COG4565	transcriptional regulatory protein
CLI97_RS05855	COG1744	ABC transporter substrate-binding protein PnrA-like
CLI97_RS05860	COG3845	ABC transporter
CLI97_RS05865	COG4603	Belongs to the binding-protein-dependent transport system permease family
CLI97_RS05870	COG1079	Belongs to the binding-protein-dependent transport system permease family
CLI97_RS05880	COG2111	Na H antiporter
CLI97_RS05880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLI97_RS05885	COG2111	Na H antiporter
CLI97_RS05890	COG1006	Multisubunit Na H antiporter MnhC subunit
CLI97_RS05895	COG0651	ATP synthesis coupled electron transport
CLI97_RS05900	COG1863	multisubunit Na H antiporter MnhE subunit
CLI97_RS05905	COG2212	antiporter activity
CLI97_RS05910	COG1320	monovalent cation:proton antiporter activity
CLI97_RS05915	COG2050	protein possibly involved in aromatic compounds catabolism
CLI97_RS05920	COG2197	response regulator
CLI97_RS05925	COG4585	Histidine kinase
CLI97_RS05935	COG0142	geranyltranstransferase activity
CLI97_RS05955	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CLI97_RS05960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLI97_RS05965	COG1335	isochorismatase
CLI97_RS05970	COG5506	Protein of unknown function (DUF1694)
CLI97_RS05985	COG0628	permease
CLI97_RS05995	COG1418	mRNA catabolic process
CLI97_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS06010	COG1511	domain protein
CLI97_RS06015	COG0433	COG0433 Predicted ATPase
CLI97_RS06015	COG1674	ftsk spoiiie
CLI97_RS06020	COG4499	WXG100 protein secretion system (Wss), protein YukC
CLI97_RS06025	COG5417	Belongs to the EsaB family
CLI97_RS06030	COG4842	Belongs to the WXG100 family
CLI97_RS06035	COG2508	Transcriptional regulator
CLI97_RS06035	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CLI97_RS06040	COG0686	Belongs to the AlaDH PNT family
CLI97_RS06045	COG5634	Uncharacterized conserved protein (DUF2278)
CLI97_RS06050	COG3251	PFAM MbtH domain protein
CLI97_RS06055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS06060	COG1535	isochorismatase
CLI97_RS06060	COG3433	isochorismatase activity
CLI97_RS06065	COG1021	2,3-dihydroxybenzoate-AMP ligase
CLI97_RS06070	COG1169	isochorismate synthase
CLI97_RS06075	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS06080	COG2819	hydrolase of the alpha beta superfamily
CLI97_RS06085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CLI97_RS06090	COG1268	BioY protein
CLI97_RS06095	COG2056	Na+-H+ antiporter family
CLI97_RS06105	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CLI97_RS06110	COG3584	3D domain protein
CLI97_RS06120	COG1252	NADH dehydrogenase
CLI97_RS06150	COG1131	(ABC) transporter
CLI97_RS06170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI97_RS06175	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CLI97_RS06180	COG0316	Belongs to the HesB IscA family
CLI97_RS06190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLI97_RS06200	COG1252	NADH dehydrogenase
CLI97_RS06205	COG4837	Protein of unknown function (DUF1462)
CLI97_RS06210	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CLI97_RS06215	COG1506	peptidase
CLI97_RS06215	COG0823	Involved in the tonB-independent uptake of proteins
CLI97_RS06215	COG4946	Tricorn protease homolog
CLI97_RS06225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CLI97_RS06230	COG0460	homoserine dehydrogenase
CLI97_RS06235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLI97_RS06240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CLI97_RS06245	COG0647	UMP catabolic process
CLI97_RS06250	COG2445	Protein of unknown function DUF86
CLI97_RS06255	COG4470	Protein conserved in bacteria
CLI97_RS06270	COG0739	heme binding
CLI97_RS06280	COG0737	Belongs to the 5'-nucleotidase family
CLI97_RS06285	COG0730	response to heat
CLI97_RS06290	COG1801	Protein of unknown function DUF72
CLI97_RS06305	COG2508	Transcriptional regulator
CLI97_RS06335	COG2814	Major facilitator Superfamily
CLI97_RS06340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CLI97_RS06345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLI97_RS06350	COG2356	endonuclease I
CLI97_RS06355	COG3842	ATPase activity
CLI97_RS06360	COG2188	Transcriptional regulator
CLI97_RS06365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI97_RS06370	COG0395	ABC-type sugar transport system, permease component
CLI97_RS06375	COG1175	transmembrane transport
CLI97_RS06380	COG1653	transport
CLI97_RS06385	COG2222	sugar isomerase
CLI97_RS06390	COG0789	Transcriptional regulator
CLI97_RS06415	COG0322	excinuclease ABC activity
CLI97_RS06420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLI97_RS06425	COG2226	methyltransferase
CLI97_RS06435	COG3409	Peptidoglycan-binding domain 1 protein
CLI97_RS06440	COG0719	Fe-S assembly protein
CLI97_RS06445	COG0822	iron-sulfur transferase activity
CLI97_RS06450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLI97_RS06455	COG0719	Fe-S assembly protein
CLI97_RS06460	COG0396	ATPase activity
CLI97_RS06470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLI97_RS06475	COG1464	Belongs to the NlpA lipoprotein family
CLI97_RS06480	COG2011	ABC-type metal ion transport system permease component
CLI97_RS06485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLI97_RS06495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS06500	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CLI97_RS06515	COG1393	Belongs to the ArsC family
CLI97_RS06520	COG1960	acyl-CoA dehydrogenase activity
CLI97_RS06525	COG0183	Belongs to the thiolase family
CLI97_RS06530	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLI97_RS06530	COG1024	Enoyl-CoA hydratase
CLI97_RS06550	COG5577	PFAM Coat F domain
CLI97_RS06555	COG1846	Transcriptional regulator
CLI97_RS06560	COG0477	Major facilitator Superfamily
CLI97_RS06585	COG1120	ATPase activity
CLI97_RS06605	COG0783	Belongs to the Dps family
CLI97_RS06610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLI97_RS06615	COG0745	RESPONSE REGULATOR receiver
CLI97_RS06620	COG2770	Histidine kinase
CLI97_RS06620	COG2205	protein histidine kinase activity
CLI97_RS06630	COG1309	transcriptional regulator
CLI97_RS06635	COG0114	fumarate hydratase activity
CLI97_RS06645	COG0697	spore germination
CLI97_RS06650	COG0814	amino acid
CLI97_RS06660	COG2197	response regulator
CLI97_RS06665	COG4585	Histidine kinase
CLI97_RS06670	COG4758	membrane
CLI97_RS06675	COG3595	metallopeptidase activity
CLI97_RS06680	COG1842	Phage shock protein A
CLI97_RS06685	COG4758	membrane
CLI97_RS06690	COG2814	Major facilitator Superfamily
CLI97_RS06695	COG2096	Adenosyltransferase
CLI97_RS06700	COG1120	ATPase activity
CLI97_RS06705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI97_RS06710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLI97_RS06715	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS06720	COG3386	PFAM SMP-30 Gluconolaconase
CLI97_RS06725	COG2205	protein histidine kinase activity
CLI97_RS06730	COG0745	RESPONSE REGULATOR receiver
CLI97_RS06740	COG1191	sigma factor activity
CLI97_RS06750	COG2140	Oxalate decarboxylase
CLI97_RS06760	COG1120	ATPase activity
CLI97_RS06765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI97_RS06770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI97_RS06775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLI97_RS06780	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CLI97_RS06785	COG0531	amino acid
CLI97_RS06800	COG1988	membrane-bound metal-dependent
CLI97_RS06810	COG1910	domain protein
CLI97_RS06815	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLI97_RS06820	COG4149	molybdate abc transporter
CLI97_RS06825	COG2197	response regulator
CLI97_RS06830	COG3850	Histidine kinase
CLI97_RS06835	COG1131	(ABC) transporter
CLI97_RS06845	COG0842	Transport permease protein
CLI97_RS06850	COG0656	L-ascorbic acid biosynthetic process
CLI97_RS06875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLI97_RS06880	COG3973	AAA domain
CLI97_RS06885	COG2860	membrane
CLI97_RS06895	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CLI97_RS06900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLI97_RS06905	COG2217	Heavy metal translocating P-type atpase
CLI97_RS06910	COG2217	Heavy metal translocating P-type atpase
CLI97_RS06915	COG2608	mercury ion transmembrane transporter activity
CLI97_RS06920	COG1937	Protein conserved in bacteria
CLI97_RS06925	COG0673	inositol 2-dehydrogenase activity
CLI97_RS06935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLI97_RS06940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLI97_RS06945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLI97_RS06950	COG1126	abc transporter atp-binding protein
CLI97_RS06955	COG0765	amino acid transport
CLI97_RS06960	COG0765	amino acid transport
CLI97_RS06965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI97_RS06970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI97_RS06975	COG0454	-acetyltransferase
CLI97_RS06980	COG0583	DNA-binding transcription factor activity
CLI97_RS06985	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS06990	COG2732	(Barnase) inhibitor
CLI97_RS07005	COG2732	(Barnase) inhibitor
CLI97_RS07020	COG0557	exoribonuclease II activity
CLI97_RS07025	COG1647	Serine aminopeptidase, S33
CLI97_RS07030	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLI97_RS07035	COG1476	TRANSCRIPTIONal
CLI97_RS07040	COG1396	sequence-specific DNA binding
CLI97_RS07045	COG1396	sequence-specific DNA binding
CLI97_RS07050	COG1733	regulation of RNA biosynthetic process
CLI97_RS07075	COG1131	(ABC) transporter
CLI97_RS07080	COG1174	glycine betaine transport
CLI97_RS07085	COG1732	Glycine betaine
CLI97_RS07090	COG1174	glycine betaine transport
CLI97_RS07095	COG0517	IMP dehydrogenase activity
CLI97_RS07095	COG1125	glycine betaine transport
CLI97_RS07100	COG1510	regulation of RNA biosynthetic process
CLI97_RS07105	COG1174	glycine betaine transport
CLI97_RS07110	COG1732	Glycine betaine
CLI97_RS07115	COG1174	glycine betaine transport
CLI97_RS07120	COG0517	IMP dehydrogenase activity
CLI97_RS07120	COG1125	glycine betaine transport
CLI97_RS07125	COG1510	regulation of RNA biosynthetic process
CLI97_RS07130	COG2095	MarC family integral membrane protein
CLI97_RS07140	COG3064	Membrane
CLI97_RS07145	COG4640	response to antibiotic
CLI97_RS07150	COG0456	acetyltransferase
CLI97_RS07165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLI97_RS07180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLI97_RS07185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI97_RS07190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLI97_RS07200	COG2234	aminopeptidase activity
CLI97_RS07220	COG0126	phosphoglycerate kinase activity
CLI97_RS07230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLI97_RS07235	COG2390	Transcriptional regulator
CLI97_RS07240	COG2814	Major facilitator Superfamily
CLI97_RS07245	COG1609	Transcriptional regulator
CLI97_RS07250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLI97_RS07260	COG0583	DNA-binding transcription factor activity
CLI97_RS07265	COG0697	spore germination
CLI97_RS07270	COG1113	amino acid transport
CLI97_RS07280	COG1609	Transcriptional regulator
CLI97_RS07290	COG0561	phosphatase activity
CLI97_RS07295	COG1737	Transcriptional regulator
CLI97_RS07300	COG1070	Carbohydrate kinase
CLI97_RS07325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLI97_RS07330	COG2186	Transcriptional regulator
CLI97_RS07335	COG1620	l-lactate permease
CLI97_RS07340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CLI97_RS07350	COG5039	Polysaccharide pyruvyl transferase
CLI97_RS07355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLI97_RS07360	COG0110	maltose O-acetyltransferase activity
CLI97_RS07365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLI97_RS07370	COG2244	polysaccharide biosynthetic process
CLI97_RS07375	COG1216	Glycosyl transferase, family 2
CLI97_RS07380	COG5039	Polysaccharide pyruvyl transferase
CLI97_RS07385	COG1216	Glycosyl transferase, family 2
CLI97_RS07395	COG0438	transferase activity, transferring glycosyl groups
CLI97_RS07400	COG1215	transferase activity, transferring glycosyl groups
CLI97_RS07405	COG0438	transferase activity, transferring glycosyl groups
CLI97_RS07410	COG1086	Polysaccharide biosynthesis protein
CLI97_RS07415	COG0489	protein tyrosine kinase activity
CLI97_RS07420	COG3944	biosynthesis protein
CLI97_RS07425	COG1396	sequence-specific DNA binding
CLI97_RS07430	COG2272	Belongs to the type-B carboxylesterase lipase family
CLI97_RS07440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLI97_RS07445	COG2364	Membrane
CLI97_RS07450	COG0456	acetyltransferase
CLI97_RS07455	COG3479	Phenolic acid decarboxylase
CLI97_RS07530	COG2223	nitrite transmembrane transporter activity
CLI97_RS07535	COG1609	Transcriptional regulator
CLI97_RS07545	COG0583	DNA-binding transcription factor activity
CLI97_RS07550	COG2828	Protein conserved in bacteria
CLI97_RS07555	COG2814	Major facilitator Superfamily
CLI97_RS07555	COG0477	Major facilitator Superfamily
CLI97_RS07560	COG1611	Belongs to the LOG family
CLI97_RS07565	COG1694	Mazg nucleotide pyrophosphohydrolase
CLI97_RS07570	COG0659	secondary active sulfate transmembrane transporter activity
CLI97_RS07575	COG0288	reversible hydration of carbon dioxide
CLI97_RS07585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLI97_RS07590	COG4290	ribonuclease
CLI97_RS07595	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CLI97_RS07600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI97_RS07610	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CLI97_RS07620	COG1051	belongs to the nudix hydrolase family
CLI97_RS07625	COG0492	ferredoxin-NADP+ reductase activity
CLI97_RS07630	COG0791	NLP P60 protein
CLI97_RS07630	COG3883	PFAM NLP P60 protein
CLI97_RS07635	COG0457	Tetratricopeptide repeat
CLI97_RS07640	COG5002	protein histidine kinase activity
CLI97_RS07645	COG0745	RESPONSE REGULATOR receiver
CLI97_RS07650	COG1132	(ABC) transporter
CLI97_RS07655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLI97_RS07655	COG0140	phosphoribosyl-ATP diphosphatase activity
CLI97_RS07680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLI97_RS07695	COG4990	cell redox homeostasis
CLI97_RS07700	COG0110	maltose O-acetyltransferase activity
CLI97_RS07720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLI97_RS07730	COG2188	Transcriptional regulator
CLI97_RS07735	COG1309	transcriptional regulator
CLI97_RS07740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLI97_RS07745	COG1950	PFAM Membrane protein of
CLI97_RS07750	COG1983	PspC domain protein
CLI97_RS07755	COG3595	metallopeptidase activity
CLI97_RS07770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLI97_RS07780	COG4897	Protein conserved in bacteria
CLI97_RS07785	COG3848	Pyruvate phosphate dikinase
CLI97_RS07785	COG0574	Belongs to the PEP-utilizing enzyme family
CLI97_RS07790	COG1309	transcriptional regulator
CLI97_RS07795	COG2814	Major facilitator Superfamily
CLI97_RS07805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLI97_RS07815	COG0793	Belongs to the peptidase S41A family
CLI97_RS07815	COG3409	Peptidoglycan-binding domain 1 protein
CLI97_RS07820	COG3420	alginic acid biosynthetic process
CLI97_RS07825	COG2177	Part of the ABC transporter FtsEX involved in
CLI97_RS07830	COG2884	Cell division ATP-binding protein ftsE
CLI97_RS07835	COG2010	Cytochrome c
CLI97_RS07840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLI97_RS07855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLI97_RS07870	COG1516	flagellar protein fliS
CLI97_RS07875	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CLI97_RS07880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLI97_RS07900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLI97_RS07905	COG4786	Flagellar basal body rod
CLI97_RS07905	COG1256	bacterial-type flagellum assembly
CLI97_RS07910	COG3418	PFAM FlgN family protein
CLI97_RS07915	COG2747	anti-sigma28 factor FlgM
CLI97_RS07925	COG1040	competence protein
CLI97_RS07935	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CLI97_RS07940	COG1307	EDD domain protein, DegV family
CLI97_RS07945	COG2197	response regulator
CLI97_RS07950	COG4585	Histidine kinase
CLI97_RS07955	COG1739	Uncharacterized protein family UPF0029
CLI97_RS07960	COG1316	TRANSCRIPTIONal
CLI97_RS07965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLI97_RS07970	COG0438	transferase activity, transferring glycosyl groups
CLI97_RS07975	COG1215	transferase activity, transferring glycosyl groups
CLI97_RS07980	COG3206	protein involved in exopolysaccharide biosynthesis
CLI97_RS07985	COG3307	-O-antigen
CLI97_RS07990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CLI97_RS07995	COG0297	glycogen (starch) synthase activity
CLI97_RS07995	COG0438	transferase activity, transferring glycosyl groups
CLI97_RS08000	COG2244	polysaccharide biosynthetic process
CLI97_RS08010	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS08010	COG2247	cell wall binding repeat
CLI97_RS08015	COG2385	sporulation resulting in formation of a cellular spore
CLI97_RS08015	COG2247	cell wall binding repeat
CLI97_RS08025	COG1316	TRANSCRIPTIONal
CLI97_RS08030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLI97_RS08035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLI97_RS08040	COG1134	teichoic acid transport
CLI97_RS08045	COG1682	transport, permease protein
CLI97_RS08050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CLI97_RS08060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CLI97_RS08065	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CLI97_RS08070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CLI97_RS08075	COG4193	domain, Protein
CLI97_RS08080	COG1482	cell wall glycoprotein biosynthetic process
CLI97_RS08085	COG0697	spore germination
CLI97_RS08090	COG0814	amino acid
CLI97_RS08100	COG1215	transferase activity, transferring glycosyl groups
CLI97_RS08105	COG2814	Major facilitator Superfamily
CLI97_RS08110	COG1316	TRANSCRIPTIONal
CLI97_RS08115	COG0561	phosphatase activity
CLI97_RS08120	COG2433	Pfam Transposase IS66
CLI97_RS08125	COG0791	NLP P60 protein
CLI97_RS08135	COG2843	Capsule synthesis protein
CLI97_RS08145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLI97_RS08155	COG0697	spore germination
CLI97_RS08160	COG0814	amino acid
CLI97_RS08170	COG1609	Transcriptional regulator
CLI97_RS08175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI97_RS08185	COG1129	ABC transporter
CLI97_RS08190	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLI97_RS08195	COG1879	ABC-type sugar transport system periplasmic component
CLI97_RS08200	COG3103	Sh3 type 3 domain protein
CLI97_RS08205	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLI97_RS08210	COG3527	Alpha-acetolactate decarboxylase
CLI97_RS08215	COG0028	Belongs to the TPP enzyme family
CLI97_RS08220	COG0583	DNA-binding transcription factor activity
CLI97_RS08225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLI97_RS08240	COG5337	Spore coat protein CotH
CLI97_RS08250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLI97_RS08260	COG0405	Gamma-glutamyltransferase
CLI97_RS08265	COG1522	sequence-specific DNA binding
CLI97_RS08270	COG2059	Chromate
CLI97_RS08275	COG2059	Chromate
CLI97_RS08285	COG0655	NAD(P)H dehydrogenase (quinone) activity
CLI97_RS08290	COG0583	DNA-binding transcription factor activity
CLI97_RS08315	COG5444	nuclease activity
CLI97_RS08330	COG3878	Protein conserved in bacteria
CLI97_RS08335	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CLI97_RS08340	COG4464	protein tyrosine phosphatase activity
CLI97_RS08345	COG0489	protein tyrosine kinase activity
CLI97_RS08350	COG3944	biosynthesis protein
CLI97_RS08365	COG4715	Zinc finger, swim domain protein
CLI97_RS08370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLI97_RS08380	COG1349	DNA-binding transcription factor activity
CLI97_RS08385	COG0629	single-stranded DNA binding
CLI97_RS08410	COG0457	Tetratricopeptide repeat
CLI97_RS08415	COG4786	Flagellar basal body rod
CLI97_RS08420	COG4786	Flagellar basal body rod
CLI97_RS08425	COG1077	Cell shape determining protein MreB Mrl
CLI97_RS08430	COG1609	Transcriptional regulator
CLI97_RS08435	COG1846	Transcriptional regulator
CLI97_RS08440	COG2814	Major facilitator Superfamily
CLI97_RS08445	COG1953	Uracil, thiamine, allantoin
CLI97_RS08450	COG0477	Major facilitator Superfamily
CLI97_RS08455	COG1335	isochorismatase
CLI97_RS08460	COG0004	ammonium transporteR
CLI97_RS08465	COG0347	Belongs to the P(II) protein family
CLI97_RS08470	COG0772	Belongs to the SEDS family
CLI97_RS08475	COG0671	phosphoesterase, PA-phosphatase related
CLI97_RS08485	COG0739	heme binding
CLI97_RS08490	COG1247	-acetyltransferase
CLI97_RS08505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLI97_RS08515	COG0726	polysaccharide deacetylase
CLI97_RS08525	COG1959	2 iron, 2 sulfur cluster binding
CLI97_RS08540	COG0831	urea catabolic process
CLI97_RS08550	COG1994	Peptidase M50
CLI97_RS08555	COG0457	Tetratricopeptide repeat
CLI97_RS08565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CLI97_RS08575	COG2304	oxidoreductase activity
CLI97_RS08580	COG2304	oxidoreductase activity
CLI97_RS08585	COG2385	sporulation resulting in formation of a cellular spore
CLI97_RS08590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLI97_RS08600	COG4836	Membrane
CLI97_RS08670	COG0698	ribose 5-phosphate isomerase
CLI97_RS08675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLI97_RS08685	COG0009	L-threonylcarbamoyladenylate synthase
CLI97_RS08690	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CLI97_RS08710	COG2890	protein-(glutamine-N5) methyltransferase activity
CLI97_RS08715	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLI97_RS08720	COG0346	lactoylglutathione lyase activity
CLI97_RS08725	COG0789	Transcriptional regulator
CLI97_RS08730	COG0679	Auxin Efflux Carrier
CLI97_RS08735	COG0281	malic enzyme
CLI97_RS08750	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLI97_RS08755	COG1494	fructose-1,6-bisphosphatase
CLI97_RS08760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLI97_RS08770	COG0191	fructose-bisphosphate aldolase activity
CLI97_RS08775	COG2204	response regulator
CLI97_RS08780	COG4821	SIS domain
CLI97_RS08795	COG2181	nitrate reductase activity
CLI97_RS08795	COG0247	lactate metabolic process
CLI97_RS08800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLI97_RS08815	COG1132	(ABC) transporter
CLI97_RS08820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLI97_RS08830	COG2181	nitrate reductase activity
CLI97_RS08835	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CLI97_RS08840	COG1140	nitrate reductase beta subunit
CLI97_RS08845	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CLI97_RS08850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLI97_RS08860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLI97_RS08865	COG2223	nitrite transmembrane transporter activity
CLI97_RS08875	COG4506	Protein conserved in bacteria
CLI97_RS08880	COG0457	Tetratricopeptide repeat
CLI97_RS08910	COG0018	arginyl-trna synthetase
CLI97_RS08915	COG0010	Belongs to the arginase family
CLI97_RS08920	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CLI97_RS08925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLI97_RS08940	COG1994	Peptidase M50
CLI97_RS08945	COG1942	4-Oxalocrotonate Tautomerase
CLI97_RS08950	COG1846	Transcriptional regulator
CLI97_RS08960	COG0531	amino acid
CLI97_RS08965	COG3465	dGTPase activity
CLI97_RS08970	COG1078	dGTPase activity
CLI97_RS08985	COG1695	Transcriptional regulator
CLI97_RS08995	COG1131	(ABC) transporter
CLI97_RS09000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CLI97_RS09030	COG0583	DNA-binding transcription factor activity
CLI97_RS09040	COG0280	phosphate acetyltransferase
CLI97_RS09050	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS09055	COG0436	Aminotransferase
CLI97_RS09085	COG2814	Major facilitator Superfamily
CLI97_RS09090	COG2814	Major facilitator Superfamily
CLI97_RS09095	COG0833	amino acid
CLI97_RS09100	COG4187	Peptidase family M20/M25/M40
CLI97_RS09105	COG1012	belongs to the aldehyde dehydrogenase family
CLI97_RS09110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLI97_RS09120	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CLI97_RS09125	COG1091	dTDP-4-dehydrorhamnose reductase activity
CLI97_RS09130	COG1088	dTDP-glucose 4,6-dehydratase activity
CLI97_RS09135	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CLI97_RS09140	COG3980	spore coat polysaccharide biosynthesis protein
CLI97_RS09145	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CLI97_RS09150	COG2089	acid synthase
CLI97_RS09155	COG0456	acetyltransferase
CLI97_RS09160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLI97_RS09165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CLI97_RS09170	COG0463	Glycosyl transferase, family 2
CLI97_RS09180	COG2363	Small membrane protein
CLI97_RS09185	COG2233	PERMEase
CLI97_RS09200	COG1216	Glycosyl transferase, family 2
CLI97_RS09215	COG1695	Transcriptional regulator
CLI97_RS09220	COG0351	phosphomethylpyrimidine kinase
CLI97_RS09230	COG1621	beta-fructofuranosidase activity
CLI97_RS09235	COG1263	PTS System
CLI97_RS09235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI97_RS09240	COG3711	transcriptional antiterminator
CLI97_RS09250	COG1404	Belongs to the peptidase S8 family
CLI97_RS09255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLI97_RS09260	COG0778	Nitroreductase
CLI97_RS09265	COG0772	Belongs to the SEDS family
CLI97_RS09290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLI97_RS09295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLI97_RS09300	COG2261	transglycosylase associated protein
CLI97_RS09305	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CLI97_RS09310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CLI97_RS09315	COG2246	polysaccharide biosynthetic process
CLI97_RS09320	COG1309	transcriptional regulator
CLI97_RS09340	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CLI97_RS09345	COG2837	iron assimilation
CLI97_RS09350	COG2822	iron ion transport
CLI97_RS09365	COG0583	DNA-binding transcription factor activity
CLI97_RS09375	COG1346	cytolysis
CLI97_RS09380	COG4895	conserved protein (DUF2196)
CLI97_RS09385	COG0789	Transcriptional regulator
CLI97_RS09390	COG5504	Zn-dependent protease
CLI97_RS09395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLI97_RS09400	COG0346	lactoylglutathione lyase activity
CLI97_RS09405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLI97_RS09410	COG1404	Belongs to the peptidase S8 family
CLI97_RS09415	COG1442	glycosyl transferase family 8
CLI97_RS09425	COG2357	RelA SpoT domain protein
CLI97_RS09430	COG1575	Belongs to the MenA family. Type 1 subfamily
CLI97_RS09450	COG1696	Membrane protein involved in D-alanine export
CLI97_RS09460	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CLI97_RS09465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLI97_RS09470	COG1486	melibiose metabolic process
CLI97_RS09475	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLI97_RS09480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLI97_RS09485	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLI97_RS09490	COG3711	transcriptional antiterminator
CLI97_RS09490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI97_RS09505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI97_RS09510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI97_RS09520	COG0640	Transcriptional regulator
CLI97_RS09525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLI97_RS09535	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLI97_RS09540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLI97_RS09545	COG2723	6-phospho-beta-galactosidase activity
CLI97_RS09550	COG1940	carbohydrate kinase activity
CLI97_RS09555	COG1482	cell wall glycoprotein biosynthetic process
CLI97_RS09565	COG0753	catalase activity
CLI97_RS09570	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CLI97_RS09575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLI97_RS09580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLI97_RS09585	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLI97_RS09590	COG4988	ABC transporter
CLI97_RS09595	COG1294	oxidase, subunit
CLI97_RS09600	COG1271	oxidase subunit
CLI97_RS09605	COG3493	citrate carrier protein
CLI97_RS09610	COG0726	polysaccharide deacetylase
CLI97_RS09615	COG3842	ATPase activity
CLI97_RS09620	COG2508	Transcriptional regulator
CLI97_RS09625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLI97_RS09635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLI97_RS09645	COG4894	glucomannan catabolic process
CLI97_RS09650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLI97_RS09655	COG0500	methyltransferase
CLI97_RS09660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLI97_RS09680	COG0753	catalase activity
CLI97_RS09680	COG0693	protein deglycase activity
CLI97_RS09685	COG2851	Citrate transporter
CLI97_RS09690	COG2273	Hydrolase Family 16
CLI97_RS09700	COG2270	Major facilitator Superfamily
CLI97_RS09705	COG0513	Belongs to the DEAD box helicase family
CLI97_RS09740	COG3209	COG3209 Rhs family protein
CLI97_RS09750	COG0697	spore germination
CLI97_RS09755	COG0589	response to stress
CLI97_RS09805	COG3507	Belongs to the glycosyl hydrolase 43 family
CLI97_RS09830	COG0010	Belongs to the arginase family
CLI97_RS09835	COG0833	amino acid
CLI97_RS09840	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CLI97_RS09845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLI97_RS09855	COG2390	Transcriptional regulator
CLI97_RS09860	COG0561	phosphatase activity
CLI97_RS09890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLI97_RS09895	COG5294	Protein conserved in bacteria
CLI97_RS09900	COG0577	efflux transmembrane transporter activity
CLI97_RS09905	COG1136	(ABC) transporter
CLI97_RS09910	COG2205	protein histidine kinase activity
CLI97_RS09915	COG0745	RESPONSE REGULATOR receiver
CLI97_RS09930	COG1082	Xylose isomerase domain protein TIM barrel
CLI97_RS09940	COG2814	Major facilitator Superfamily
CLI97_RS09970	COG1349	DNA-binding transcription factor activity
CLI97_RS09975	COG0667	Aldo Keto reductase
CLI97_RS09980	COG2814	Major facilitator Superfamily
CLI97_RS09995	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS10000	COG2197	response regulator
CLI97_RS10005	COG4585	Histidine kinase
CLI97_RS10010	COG3239	Fatty acid desaturase
CLI97_RS10020	COG1309	transcriptional regulator
CLI97_RS10025	COG1012	belongs to the aldehyde dehydrogenase family
CLI97_RS10030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLI97_RS10040	COG0640	Transcriptional regulator
CLI97_RS10045	COG2814	Major facilitator Superfamily
CLI97_RS10050	COG1714	RDD family
CLI97_RS10060	COG0450	alkyl hydroperoxide reductase
CLI97_RS10065	COG3634	alkyl hydroperoxide reductase activity
CLI97_RS10075	COG1113	amino acid transport
CLI97_RS10085	COG2080	2 iron, 2 sulfur cluster binding
CLI97_RS10100	COG2068	MobA-Related Protein
CLI97_RS10105	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CLI97_RS10165	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CLI97_RS10170	COG0667	Aldo Keto reductase
CLI97_RS10175	COG0456	acetyltransferase
CLI97_RS10180	COG0457	Tetratricopeptide repeat
CLI97_RS10185	COG0010	Belongs to the arginase family
CLI97_RS10190	COG0833	amino acid
CLI97_RS10195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLI97_RS10200	COG5658	integral membrane protein
CLI97_RS10205	COG0640	Transcriptional regulator
CLI97_RS10210	COG3829	transcription factor binding
CLI97_RS10220	COG0488	(ABC) transporter
CLI97_RS10235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLI97_RS10250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLI97_RS10255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLI97_RS10260	COG4853	Protein conserved in bacteria
CLI97_RS10265	COG4863	YycH protein
CLI97_RS10270	COG5002	protein histidine kinase activity
CLI97_RS10275	COG0745	RESPONSE REGULATOR receiver
CLI97_RS10310	COG0346	lactoylglutathione lyase activity
CLI97_RS10315	COG0305	Participates in initiation and elongation during chromosome replication
CLI97_RS10330	COG3093	addiction module antidote protein HigA
CLI97_RS10340	COG0297	glycogen (starch) synthase activity
CLI97_RS10350	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CLI97_RS10355	COG0438	transferase activity, transferring glycosyl groups
CLI97_RS10375	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CLI97_RS10380	COG4241	membrane
CLI97_RS10390	COG5577	PFAM Coat F domain
CLI97_RS10395	COG1733	regulation of RNA biosynthetic process
CLI97_RS10405	COG0697	spore germination
CLI97_RS10410	COG1621	beta-fructofuranosidase activity
CLI97_RS10415	COG1621	beta-fructofuranosidase activity
CLI97_RS10425	COG2318	DinB family
CLI97_RS10430	COG2211	Major facilitator Superfamily
CLI97_RS10440	COG0778	Nitroreductase
CLI97_RS10445	COG1846	Transcriptional regulator
CLI97_RS10450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLI97_RS10455	COG1846	Transcriptional regulator
CLI97_RS10460	COG2153	protein acetylation
CLI97_RS10465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLI97_RS10470	COG0697	spore germination
CLI97_RS10475	COG1331	Highly conserved protein containing a thioredoxin domain
CLI97_RS10490	COG1331	Highly conserved protein containing a thioredoxin domain
CLI97_RS10495	COG1266	CAAX protease self-immunity
CLI97_RS10500	COG0477	Major facilitator Superfamily
CLI97_RS10500	COG2814	Major facilitator Superfamily
CLI97_RS10505	COG0346	lactoylglutathione lyase activity
CLI97_RS10510	COG1609	Transcriptional regulator
CLI97_RS10515	COG0708	Exodeoxyribonuclease III
CLI97_RS10520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLI97_RS10525	COG2169	Transcriptional regulator
CLI97_RS10535	COG0629	single-stranded DNA binding
CLI97_RS10545	COG0012	GTP binding
CLI97_RS10550	COG0243	molybdopterin cofactor binding
CLI97_RS10555	COG4481	Protein conserved in bacteria
CLI97_RS10560	COG3949	Membrane
CLI97_RS10575	COG1475	DNA binding
CLI97_RS10580	COG1192	Involved in chromosome partitioning
CLI97_RS10605	COG1847	R3H domain protein
CLI97_RS10610	COG0706	membrane insertase activity
CLI97_RS10630	COG0592	DNA-directed DNA polymerase activity
CLI97_RS10635	COG2501	S4 domain
CLI97_RS10650	COG0187	DNA topoisomerase II activity
CLI97_RS10655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLI97_RS10690	COG0516	GMP reductase activity
CLI97_RS10690	COG0517	IMP dehydrogenase activity
CLI97_RS10695	COG1686	Belongs to the peptidase S11 family
CLI97_RS10715	COG1929	Belongs to the glycerate kinase type-1 family
CLI97_RS10725	COG1428	Deoxynucleoside kinase
CLI97_RS10730	COG1428	Deoxynucleoside kinase
CLI97_RS10735	COG3858	chitin binding
CLI97_RS10735	COG1388	LysM domain
CLI97_RS10740	COG1335	isochorismatase
CLI97_RS10745	COG0590	tRNA wobble adenosine to inosine editing
CLI97_RS10755	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLI97_RS10760	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLI97_RS10810	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CLI97_RS10815	COG3853	Toxic anion resistance protein (TelA)
CLI97_RS10820	COG1982	Orn Lys Arg decarboxylase major
CLI97_RS10830	COG3870	Protein conserved in bacteria
CLI97_RS10835	COG1728	Protein conserved in bacteria
CLI97_RS10840	COG0470	DNA polymerase III
CLI97_RS10845	COG1774	PSP1 C-terminal conserved region
CLI97_RS10855	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CLI97_RS10865	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLI97_RS10870	COG2002	toxin-antitoxin pair type II binding
CLI97_RS10875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI97_RS10875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI97_RS10880	COG0084	hydrolase, TatD family'
CLI97_RS10885	COG3584	3D domain protein
CLI97_RS10885	COG3583	domain protein
CLI97_RS10890	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CLI97_RS10895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLI97_RS10905	COG4466	Protein conserved in bacteria
CLI97_RS10920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLI97_RS10925	COG0251	oxidation-reduction process
CLI97_RS10940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLI97_RS10960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLI97_RS10965	COG2002	toxin-antitoxin pair type II binding
CLI97_RS10970	COG2244	polysaccharide biosynthetic process
CLI97_RS10975	COG3956	TIGRFAM MazG family protein
CLI97_RS10980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CLI97_RS10995	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CLI97_RS11000	COG1098	S1 RNA binding domain
CLI97_RS11015	COG2208	phosphoserine phosphatase activity
CLI97_RS11020	COG2304	oxidoreductase activity
CLI97_RS11025	COG0515	serine threonine protein kinase
CLI97_RS11030	COG0037	tRNA processing
CLI97_RS11035	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CLI97_RS11040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLI97_RS11055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLI97_RS11060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLI97_RS11065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLI97_RS11070	COG0512	Glutamine amidotransferase of anthranilate synthase
CLI97_RS11075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLI97_RS11080	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLI97_RS11085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLI97_RS11090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLI97_RS11095	COG1396	sequence-specific DNA binding
CLI97_RS11100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLI97_RS11105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLI97_RS11190	COG4463	regulation of RNA biosynthetic process
CLI97_RS11195	COG3880	PFAM UvrB UvrC protein
CLI97_RS11205	COG0542	response to heat
CLI97_RS11210	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLI97_RS11215	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CLI97_RS11220	COG4956	integral membrane protein (PIN domain superfamily)
CLI97_RS11240	COG1045	serine acetyltransferase
CLI97_RS11250	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CLI97_RS11255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLI97_RS11260	COG3688	RNA-binding protein containing a PIN domain
CLI97_RS11265	COG1595	DNA-templated transcription, initiation
CLI97_RS11275	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLI97_RS11280	COG0250	Participates in transcription elongation, termination and antitermination
CLI97_RS11305	COG2813	Specifically methylates the guanine in position
CLI97_RS11320	COG1358	cellular component organization or biogenesis
CLI97_RS11345	COG0596	Alpha beta hydrolase
CLI97_RS11440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLI97_RS11455	COG0201	protein transport
CLI97_RS11465	COG0024	Methionine aminopeptidase
CLI97_RS11480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLI97_RS11505	COG1122	ATPase activity
CLI97_RS11510	COG1122	ATPase activity
CLI97_RS11515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLI97_RS11535	COG2226	methyltransferase
CLI97_RS11540	COG2318	DinB family
CLI97_RS11550	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS11555	COG0489	protein tyrosine kinase activity
CLI97_RS11565	COG2194	sulfuric ester hydrolase activity
CLI97_RS11570	COG0726	polysaccharide deacetylase
CLI97_RS11630	COG0738	Major facilitator superfamily
CLI97_RS11635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLI97_RS11650	COG0659	secondary active sulfate transmembrane transporter activity
CLI97_RS11655	COG0385	Bile acid
CLI97_RS11660	COG2819	hydrolase of the alpha beta superfamily
CLI97_RS11665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI97_RS11670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI97_RS11675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLI97_RS11680	COG2207	Transcriptional regulator
CLI97_RS11680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLI97_RS11685	COG3876	Protein conserved in bacteria
CLI97_RS11690	COG1472	Belongs to the glycosyl hydrolase 3 family
CLI97_RS11695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLI97_RS11700	COG1263	PTS System
CLI97_RS11700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI97_RS11710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI97_RS11745	COG1595	DNA-templated transcription, initiation
CLI97_RS11750	COG5662	AntiSigma factor
CLI97_RS11755	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CLI97_RS11760	COG4856	YbbR-like protein
CLI97_RS11785	COG0515	serine threonine protein kinase
CLI97_RS11790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLI97_RS11800	COG1346	cytolysis
CLI97_RS11805	COG1380	Effector of murein hydrolase LrgA
CLI97_RS11810	COG1846	Transcriptional regulator
CLI97_RS11815	COG1113	amino acid transport
CLI97_RS11820	COG1011	Hydrolase
CLI97_RS11825	COG4585	Histidine kinase
CLI97_RS11830	COG2197	response regulator
CLI97_RS11835	COG1131	(ABC) transporter
CLI97_RS11875	COG0531	amino acid
CLI97_RS11900	COG0584	glycerophosphoryl diester phosphodiesterase
CLI97_RS11905	COG2271	Major facilitator Superfamily
CLI97_RS11920	COG2368	4-hydroxyphenylacetate
CLI97_RS11930	COG3409	Peptidoglycan-binding domain 1 protein
CLI97_RS11945	COG0371	Dehydrogenase
CLI97_RS11955	COG1183	phosphatidylcholine synthase activity
CLI97_RS11960	COG0586	Pfam SNARE associated Golgi protein
CLI97_RS11965	COG0688	phosphatidylethanolamine metabolic process
CLI97_RS11980	COG1301	dicarboxylic acid transport
CLI97_RS11985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLI97_RS11990	COG0833	amino acid
CLI97_RS11995	COG2040	homocysteine
CLI97_RS12000	COG1115	amino acid carrier protein
CLI97_RS12005	COG2066	Belongs to the glutaminase family
CLI97_RS12010	COG4191	Histidine kinase
CLI97_RS12015	COG0784	Response regulator, receiver
CLI97_RS12020	COG3173	Aminoglycoside phosphotransferase
CLI97_RS12030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLI97_RS12035	COG0778	Nitroreductase
CLI97_RS12045	COG2259	Doxx family
CLI97_RS12050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS12070	COG3773	Cell wall hydrolase
CLI97_RS12080	COG3540	Alkaline phosphatase
CLI97_RS12085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLI97_RS12090	COG0805	protein transport
CLI97_RS12100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLI97_RS12105	COG0477	Major facilitator Superfamily
CLI97_RS12110	COG1309	transcriptional regulator
CLI97_RS12115	COG0252	asparaginase activity
CLI97_RS12120	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CLI97_RS12125	COG3012	SEC-C Motif Domain Protein
CLI97_RS12125	COG1405	negative regulation of cell septum assembly
CLI97_RS12130	COG0667	Aldo Keto reductase
CLI97_RS12140	COG1595	DNA-templated transcription, initiation
CLI97_RS12145	COG1595	DNA-templated transcription, initiation
CLI97_RS12150	COG1876	peptidase activity
CLI97_RS12155	COG0457	Tetratricopeptide repeat
CLI97_RS12160	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS12165	COG0366	Alpha amylase catalytic
CLI97_RS12170	COG0803	Belongs to the bacterial solute-binding protein 9 family
CLI97_RS12175	COG1121	(ABC) transporter
CLI97_RS12180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLI97_RS12185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLI97_RS12190	COG2310	stress, protein
CLI97_RS12195	COG2310	stress, protein
CLI97_RS12200	COG2310	stress, protein
CLI97_RS12205	COG0861	Integral membrane protein TerC family
CLI97_RS12215	COG3853	Toxic anion resistance protein (TelA)
CLI97_RS12220	COG0477	Major facilitator Superfamily
CLI97_RS12225	COG2814	Major facilitator Superfamily
CLI97_RS12230	COG0640	Transcriptional regulator
CLI97_RS12235	COG4175	Glycine betaine
CLI97_RS12235	COG0517	IMP dehydrogenase activity
CLI97_RS12240	COG4176	ABC-type proline glycine betaine transport system permease component
CLI97_RS12245	COG2113	Glycine betaine
CLI97_RS12250	COG1473	amidohydrolase
CLI97_RS12255	COG1288	antiporter activity
CLI97_RS12265	COG0366	Alpha amylase catalytic
CLI97_RS12275	COG2814	Major facilitator Superfamily
CLI97_RS12280	COG1846	Transcriptional regulator
CLI97_RS12290	COG1280	lysine exporter protein (LysE YggA)
CLI97_RS12295	COG3403	YqcI/YcgG family
CLI97_RS12300	COG1113	amino acid transport
CLI97_RS12305	COG3665	Urea carboxylase-associated protein
CLI97_RS12320	COG1660	Displays ATPase and GTPase activities
CLI97_RS12330	COG2271	Major facilitator Superfamily
CLI97_RS12335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLI97_RS12340	COG3458	cephalosporin-C deacetylase activity
CLI97_RS12345	COG3541	Predicted nucleotidyltransferase
CLI97_RS12350	COG0506	proline dehydrogenase activity
CLI97_RS12355	COG1012	belongs to the aldehyde dehydrogenase family
CLI97_RS12360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLI97_RS12365	COG2508	Transcriptional regulator
CLI97_RS12375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLI97_RS12375	COG1587	Uroporphyrinogen-III synthase
CLI97_RS12380	COG2146	nitrite reductase [NAD(P)H] activity
CLI97_RS12385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLI97_RS12390	COG0523	cobalamin synthesis protein
CLI97_RS12395	COG1063	alcohol dehydrogenase
CLI97_RS12400	COG1714	RDD family
CLI97_RS12410	COG2723	6-phospho-beta-galactosidase activity
CLI97_RS12425	COG3209	COG3209 Rhs family protein
CLI97_RS12430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CLI97_RS12435	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CLI97_RS12440	COG1733	regulation of RNA biosynthetic process
CLI97_RS12445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS12450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS12455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS12460	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CLI97_RS12475	COG2364	Membrane
CLI97_RS12480	COG1126	abc transporter atp-binding protein
CLI97_RS12485	COG0765	amino acid transport
CLI97_RS12490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI97_RS12495	COG0583	DNA-binding transcription factor activity
CLI97_RS12500	COG0163	prenyltransferase activity
CLI97_RS12505	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLI97_RS12520	COG3104	oligopeptide transport
CLI97_RS12525	COG5434	Belongs to the glycosyl hydrolase 28 family
CLI97_RS12535	COG0697	spore germination
CLI97_RS12545	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLI97_RS12550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLI97_RS12555	COG0456	acetyltransferase
CLI97_RS12560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI97_RS12565	COG0765	amino acid transport
CLI97_RS12570	COG1126	abc transporter atp-binding protein
CLI97_RS12575	COG1473	amidohydrolase
CLI97_RS12580	COG2079	MmgE PrpD family protein
CLI97_RS12585	COG1136	(ABC) transporter
CLI97_RS12590	COG0577	efflux transmembrane transporter activity
CLI97_RS12595	COG0745	RESPONSE REGULATOR receiver
CLI97_RS12600	COG3850	Histidine kinase
CLI97_RS12600	COG5002	protein histidine kinase activity
CLI97_RS12605	COG0457	Tetratricopeptide repeat
CLI97_RS12620	COG0527	aspartate kinase activity
CLI97_RS12625	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI97_RS12630	COG4605	iron ion homeostasis
CLI97_RS12635	COG4604	ABC transporter, ATP-binding protein
CLI97_RS12640	COG4607	ABC-type enterochelin transport system periplasmic component
CLI97_RS12645	COG2814	Major facilitator Superfamily
CLI97_RS12650	COG1309	transcriptional regulator
CLI97_RS12655	COG0778	Nitroreductase
CLI97_RS12660	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CLI97_RS12665	COG0640	Transcriptional regulator
CLI97_RS12670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLI97_RS12675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLI97_RS12680	COG1012	belongs to the aldehyde dehydrogenase family
CLI97_RS12685	COG4975	Glucose uptake
CLI97_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS12695	COG4549	nuclear export factor GLE1
CLI97_RS12700	COG2372	response to copper ion
CLI97_RS12700	COG1276	copper resistance
CLI97_RS12705	COG1349	DNA-binding transcription factor activity
CLI97_RS12715	COG2213	PTS system mannitol-specific
CLI97_RS12720	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI97_RS12730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLI97_RS12740	COG0561	phosphatase activity
CLI97_RS12750	COG1914	H( )-stimulated, divalent metal cation uptake system
CLI97_RS12760	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CLI97_RS12765	COG1984	allophanate hydrolase subunit 2
CLI97_RS12770	COG1414	Transcriptional regulator
CLI97_RS12775	COG2755	lipolytic protein G-D-S-L family
CLI97_RS12785	COG2329	Antibiotic biosynthesis monooxygenase
CLI97_RS12790	COG0768	penicillin binding
CLI97_RS12795	COG4989	oxidoreductase activity
CLI97_RS12800	COG3711	transcriptional antiterminator
CLI97_RS12805	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS12810	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS12815	COG1917	Cupin 2, conserved barrel domain protein
CLI97_RS12820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI97_RS12825	COG3871	stress protein (general stress protein 26)
CLI97_RS12835	COG2814	Major facilitator Superfamily
CLI97_RS12840	COG1522	sequence-specific DNA binding
CLI97_RS12845	COG0551	DNA topoisomerase type I activity
CLI97_RS12845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLI97_RS12850	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CLI97_RS12855	COG3706	GGDEF domain
CLI97_RS12860	COG5298	Protein conserved in bacteria
CLI97_RS12865	COG1215	transferase activity, transferring glycosyl groups
CLI97_RS12875	COG0531	amino acid
CLI97_RS12880	COG0494	nUDIX hydrolase
CLI97_RS12885	COG0028	Belongs to the TPP enzyme family
CLI97_RS12955	COG1914	H( )-stimulated, divalent metal cation uptake system
CLI97_RS12970	COG4876	unkown
CLI97_RS12980	COG2076	Multidrug Resistance protein
CLI97_RS12985	COG2217	Heavy metal translocating P-type atpase
CLI97_RS12990	COG3729	General stress protein
CLI97_RS12995	COG0662	Cupin 2, conserved barrel domain protein
CLI97_RS13000	COG2329	Antibiotic biosynthesis monooxygenase
CLI97_RS13005	COG3546	catalase activity
CLI97_RS13010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLI97_RS13015	COG3290	protein histidine kinase activity
CLI97_RS13020	COG4565	transcriptional regulatory protein
CLI97_RS13025	COG1301	dicarboxylic acid transport
CLI97_RS13030	COG0628	permease
CLI97_RS13035	COG1131	(ABC) transporter
CLI97_RS13040	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CLI97_RS13050	COG1960	acyl-CoA dehydrogenase activity
CLI97_RS13065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLI97_RS13070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS13080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLI97_RS13085	COG0513	Belongs to the DEAD box helicase family
CLI97_RS13090	COG3402	PFAM membrane-flanked domain
CLI97_RS13095	COG3428	Bacterial PH domain
CLI97_RS13100	COG0705	Rhomboid family
CLI97_RS13110	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CLI97_RS13115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLI97_RS13120	COG0864	Transcriptional regulator
CLI97_RS13125	COG2337	Toxic component of a toxin-antitoxin (TA) module
CLI97_RS13130	COG1366	Belongs to the anti-sigma-factor antagonist family
CLI97_RS13135	COG1366	Belongs to the anti-sigma-factor antagonist family
CLI97_RS13140	COG2172	sigma factor antagonist activity
CLI97_RS13145	COG2208	phosphoserine phosphatase activity
CLI97_RS13150	COG1366	Belongs to the anti-sigma-factor antagonist family
CLI97_RS13160	COG1191	sigma factor activity
CLI97_RS13165	COG2208	phosphoserine phosphatase activity
CLI97_RS13170	COG2183	response to ionizing radiation
CLI97_RS13220	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLI97_RS13235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLI97_RS13240	COG0477	Major facilitator Superfamily
CLI97_RS13250	COG1764	response to oxidative stress
CLI97_RS13255	COG1846	Transcriptional regulator
CLI97_RS13265	COG1959	2 iron, 2 sulfur cluster binding
CLI97_RS13270	COG2910	NAD(P)H-binding
CLI97_RS13275	COG1278	Cold shock
CLI97_RS13280	COG1329	Transcriptional regulator
CLI97_RS13285	COG1794	racemase activity, acting on amino acids and derivatives
CLI97_RS13300	COG3621	Patatin-like phospholipase
CLI97_RS13310	COG0662	Cupin 2, conserved barrel domain protein
CLI97_RS13325	COG0277	FAD linked oxidase domain protein
CLI97_RS13345	COG0662	Cupin 2, conserved barrel domain protein
CLI97_RS13350	COG2318	DinB family
CLI97_RS13355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLI97_RS13380	COG0351	phosphomethylpyrimidine kinase
CLI97_RS13395	COG1064	alcohol dehydrogenase
CLI97_RS13400	COG0789	Transcriptional regulator
CLI97_RS13410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLI97_RS13445	COG2814	Major facilitator Superfamily
CLI97_RS13450	COG1309	transcriptional regulator
CLI97_RS13455	COG5577	PFAM Coat F domain
CLI97_RS13465	COG1063	alcohol dehydrogenase
CLI97_RS13470	COG5577	PFAM Coat F domain
CLI97_RS13485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CLI97_RS13490	COG0488	(ABC) transporter
CLI97_RS13495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI97_RS13500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLI97_RS13510	COG2814	Major facilitator Superfamily
CLI97_RS13515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLI97_RS13525	COG0730	response to heat
CLI97_RS13530	COG0456	acetyltransferase
CLI97_RS13535	COG0789	Transcriptional regulator
CLI97_RS13535	COG4978	Transcriptional regulator
CLI97_RS13540	COG0697	spore germination
CLI97_RS13545	COG1051	belongs to the nudix hydrolase family
CLI97_RS13550	COG2226	methyltransferase
CLI97_RS13555	COG0473	3-isopropylmalate dehydrogenase activity
CLI97_RS13560	COG1802	Transcriptional regulator
CLI97_RS13565	COG1819	glycosyl
CLI97_RS13580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLI97_RS13585	COG1388	LysM domain
CLI97_RS13590	COG2814	Major facilitator Superfamily
CLI97_RS13595	COG2188	Transcriptional regulator
CLI97_RS13600	COG2186	Transcriptional regulator
CLI97_RS13605	COG2807	transmembrane transport
CLI97_RS13610	COG2076	Multidrug Resistance protein
CLI97_RS13615	COG2076	Multidrug Resistance protein
CLI97_RS13620	COG1309	transcriptional regulator
CLI97_RS13625	COG0531	amino acid
CLI97_RS13635	COG3832	glyoxalase III activity
CLI97_RS13640	COG0604	alcohol dehydrogenase
CLI97_RS13650	COG2814	Major facilitator Superfamily
CLI97_RS13690	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CLI97_RS13695	COG0802	atpase or kinase
CLI97_RS13700	COG1214	PFAM Peptidase M22, glycoprotease
CLI97_RS13705	COG0456	acetyltransferase
CLI97_RS13710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLI97_RS13715	COG0488	(ABC) transporter
CLI97_RS13730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLI97_RS13735	COG0805	protein transport
CLI97_RS13745	COG1266	CAAX protease self-immunity
CLI97_RS13760	COG0156	8-amino-7-oxononanoate synthase activity
CLI97_RS13780	COG3403	YqcI/YcgG family
CLI97_RS13795	COG2814	Major facilitator Superfamily
CLI97_RS13800	COG0457	Tetratricopeptide repeat
CLI97_RS13805	COG1063	alcohol dehydrogenase
CLI97_RS13810	COG2211	Major facilitator Superfamily
CLI97_RS13815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI97_RS13825	COG1842	Phage shock protein A
CLI97_RS13830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLI97_RS13835	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CLI97_RS13840	COG4260	virion core protein, lumpy skin disease virus
CLI97_RS13855	COG1595	DNA-templated transcription, initiation
CLI97_RS13860	COG1063	alcohol dehydrogenase
CLI97_RS13865	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLI97_RS13870	COG0823	Involved in the tonB-independent uptake of proteins
CLI97_RS13885	COG2132	Multicopper oxidase
CLI97_RS13890	COG1113	amino acid transport
CLI97_RS13895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLI97_RS13900	COG0714	Associated with various cellular activities
CLI97_RS13905	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CLI97_RS13910	COG1305	Transglutaminase-like
CLI97_RS13935	COG2252	PERMEase
CLI97_RS13940	COG3064	Membrane
CLI97_RS13960	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLI97_RS13965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLI97_RS13970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLI97_RS13975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CLI97_RS13980	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLI97_RS13995	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLI97_RS14005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLI97_RS14010	COG0138	bifunctional purine biosynthesis protein purh
CLI97_RS14015	COG0151	Belongs to the GarS family
CLI97_RS14025	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CLI97_RS14030	COG1470	cell adhesion involved in biofilm formation
CLI97_RS14035	COG4496	protein, YerC YecD
CLI97_RS14040	COG0069	glutamate synthase activity
CLI97_RS14055	COG0210	DNA helicase
CLI97_RS14065	COG4851	CamS sex pheromone cAM373 precursor
CLI97_RS14070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLI97_RS14075	COG1285	pathogenesis
CLI97_RS14080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLI97_RS14100	COG1309	transcriptional regulator
CLI97_RS14105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLI97_RS14110	COG1597	lipid kinase activity
CLI97_RS14115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLI97_RS14125	COG1131	(ABC) transporter
CLI97_RS14145	COG5444	nuclease activity
CLI97_RS14175	COG3546	catalase activity
CLI97_RS14180	COG0454	-acetyltransferase
CLI97_RS14190	COG2323	membrane
CLI97_RS14195	COG2329	Antibiotic biosynthesis monooxygenase
CLI97_RS14200	COG0346	lactoylglutathione lyase activity
CLI97_RS14210	COG1366	Belongs to the anti-sigma-factor antagonist family
CLI97_RS14215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CLI97_RS14220	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CLI97_RS14225	COG4208	sulfate ABC transporter
CLI97_RS14235	COG5583	Uncharacterized small protein (DUF2292)
CLI97_RS14240	COG0196	riboflavin kinase activity
CLI97_RS14245	COG0670	Belongs to the BI1 family
CLI97_RS14250	COG1846	Transcriptional regulator
CLI97_RS14255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI97_RS14265	COG2124	cytochrome p450
CLI97_RS14265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLI97_RS14270	COG1368	sulfuric ester hydrolase activity
CLI97_RS14275	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLI97_RS14280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI97_RS14285	COG1442	glycosyl transferase family 8
CLI97_RS14290	COG1216	Glycosyl transferase, family 2
CLI97_RS14295	COG1442	glycosyl transferase family 8
CLI97_RS14300	COG2223	nitrite transmembrane transporter activity
CLI97_RS14305	COG0531	amino acid
CLI97_RS14310	COG1012	belongs to the aldehyde dehydrogenase family
CLI97_RS14315	COG0840	transmembrane signaling receptor activity
CLI97_RS14320	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS14325	COG0463	Glycosyl transferase, family 2
CLI97_RS14325	COG0457	Tetratricopeptide repeat
CLI97_RS14330	COG0488	(ABC) transporter
CLI97_RS14335	COG0789	Transcriptional regulator
CLI97_RS14340	COG2814	Major facilitator Superfamily
CLI97_RS14345	COG0488	(ABC) transporter
CLI97_RS14350	COG0513	Belongs to the DEAD box helicase family
CLI97_RS14355	COG0456	acetyltransferase
CLI97_RS14360	COG2130	NADP-dependent
CLI97_RS14375	COG3866	Pectate lyase
CLI97_RS14380	COG0471	metal ion transport
CLI97_RS14400	COG3290	protein histidine kinase activity
CLI97_RS14405	COG4565	transcriptional regulatory protein
CLI97_RS14410	COG3181	Tripartite tricarboxylate transporter family receptor
CLI97_RS14415	COG2851	Citrate transporter
CLI97_RS14420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI97_RS14425	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CLI97_RS14435	COG2258	MOSC domain
CLI97_RS14455	COG0024	Methionine aminopeptidase
CLI97_RS14460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI97_RS14460	COG1263	PTS System
CLI97_RS14470	COG1368	sulfuric ester hydrolase activity
CLI97_RS14480	COG0071	Belongs to the small heat shock protein (HSP20) family
CLI97_RS14495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI97_RS14495	COG1263	PTS System
CLI97_RS14500	COG0366	Alpha amylase catalytic
CLI97_RS14505	COG2188	Transcriptional regulator
CLI97_RS14510	COG0778	Nitroreductase
CLI97_RS14525	COG0737	Belongs to the 5'-nucleotidase family
CLI97_RS14530	COG0693	protein deglycase activity
CLI97_RS14535	COG1609	Transcriptional regulator
CLI97_RS14560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLI97_RS14565	COG4980	gas vesicle protein
CLI97_RS14570	COG1295	ribonuclease BN
CLI97_RS14575	COG0477	Major facilitator Superfamily
CLI97_RS14580	COG0387	Pfam Sodium calcium exchanger
CLI97_RS14590	COG0668	transmembrane transport
CLI97_RS14595	COG0535	radical SAM domain protein
CLI97_RS14605	COG0726	polysaccharide deacetylase
CLI97_RS14610	COG2084	Dehydrogenase
CLI97_RS14620	COG0598	Magnesium transport protein CorA
CLI97_RS14625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CLI97_RS14630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLI97_RS14640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLI97_RS14645	COG4637	Psort location Cytoplasmic, score
CLI97_RS14650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CLI97_RS14655	COG0022	dehydrogenase e1 component
CLI97_RS14660	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLI97_RS14665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI97_RS14670	COG3284	Transcriptional regulator
CLI97_RS14680	COG1486	melibiose metabolic process
CLI97_RS14685	COG1737	Transcriptional regulator
CLI97_RS14690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI97_RS14690	COG1263	PTS System
CLI97_RS14695	COG1132	(ABC) transporter
CLI97_RS14700	COG1132	(ABC) transporter
CLI97_RS14705	COG2259	Doxx family
CLI97_RS14710	COG2514	catechol 2,3-dioxygenase activity
CLI97_RS14725	COG1695	Transcriptional regulator
CLI97_RS14730	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLI97_RS14735	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CLI97_RS14740	COG0574	Belongs to the PEP-utilizing enzyme family
CLI97_RS14740	COG3848	Pyruvate phosphate dikinase
CLI97_RS14745	COG2732	(Barnase) inhibitor
CLI97_RS14750	COG2318	DinB family
CLI97_RS14755	COG2814	Major facilitator Superfamily
CLI97_RS14760	COG1846	Transcriptional regulator
CLI97_RS14765	COG0392	lysyltransferase activity
CLI97_RS14765	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CLI97_RS14770	COG0384	phenazine biosynthesis protein PhzF
CLI97_RS14775	COG0778	Nitroreductase
CLI97_RS14790	COG1090	epimerase
CLI97_RS14805	COG2814	Major facilitator Superfamily
CLI97_RS14815	COG3591	Belongs to the peptidase S1B family
CLI97_RS14830	COG3103	Sh3 type 3 domain protein
CLI97_RS14835	COG5658	integral membrane protein
CLI97_RS14840	COG0596	Alpha beta hydrolase
CLI97_RS14845	COG0463	Glycosyl transferase, family 2
CLI97_RS14850	COG4485	Bacterial membrane protein, YfhO
CLI97_RS14855	COG1988	membrane-bound metal-dependent
CLI97_RS14860	COG1194	a g-specific adenine glycosylase
CLI97_RS14870	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS14890	COG1132	(ABC) transporter
CLI97_RS14895	COG4129	membrane
CLI97_RS14905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLI97_RS14910	COG0735	belongs to the Fur family
CLI97_RS15025	COG3340	Belongs to the peptidase S51 family
CLI97_RS15035	COG0277	FAD linked oxidase domain protein
CLI97_RS15045	COG0747	negative chemotaxis
CLI97_RS15050	COG0601	transmembrane transport
CLI97_RS15055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI97_RS15060	COG0444	Belongs to the ABC transporter superfamily
CLI97_RS15065	COG4608	Belongs to the ABC transporter superfamily
CLI97_RS15070	COG0753	catalase activity
CLI97_RS15080	COG1116	anion transmembrane transporter activity
CLI97_RS15085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLI97_RS15090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLI97_RS15110	COG1476	TRANSCRIPTIONal
CLI97_RS15120	COG3382	B3 4 domain protein
CLI97_RS15125	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLI97_RS15135	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CLI97_RS15140	COG0789	Transcriptional regulator
CLI97_RS15145	COG1664	Polymer-forming cytoskeletal
CLI97_RS15150	COG1664	Polymer-forming cytoskeletal
CLI97_RS15160	COG2766	serine protein kinase
CLI97_RS15175	COG1846	Transcriptional regulator
CLI97_RS15180	COG1566	PFAM secretion protein HlyD family protein
CLI97_RS15185	COG2814	Major facilitator Superfamily
CLI97_RS15190	COG0655	NAD(P)H dehydrogenase (quinone) activity
CLI97_RS15205	COG1725	Transcriptional regulator
CLI97_RS15210	COG1131	(ABC) transporter
CLI97_RS15215	COG1131	(ABC) transporter
CLI97_RS15220	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CLI97_RS15225	COG1278	Cold shock
CLI97_RS15235	COG1464	Belongs to the NlpA lipoprotein family
CLI97_RS15240	COG3706	GGDEF domain
CLI97_RS15245	COG1823	symporter activity
CLI97_RS15265	COG5577	PFAM Coat F domain
CLI97_RS15270	COG4085	toxin activity
CLI97_RS15270	COG1525	nuclease
CLI97_RS15270	COG0737	Belongs to the 5'-nucleotidase family
CLI97_RS15275	COG3764	Sortase (surface protein transpeptidase)
CLI97_RS15280	COG0564	pseudouridine synthase activity
CLI97_RS15290	COG0517	IMP dehydrogenase activity
CLI97_RS15295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLI97_RS15300	COG3153	acetyltransferase
CLI97_RS15300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLI97_RS15305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLI97_RS15310	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CLI97_RS15315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CLI97_RS15325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLI97_RS15330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLI97_RS15335	COG2203	Gaf domain
CLI97_RS15335	COG4585	Histidine kinase
CLI97_RS15340	COG2197	response regulator
CLI97_RS15345	COG0431	NADPH-dependent FMN reductase
CLI97_RS15360	COG0791	NLP P60 protein
CLI97_RS15360	COG1388	LysM domain
CLI97_RS15365	COG1959	2 iron, 2 sulfur cluster binding
CLI97_RS15370	COG0668	transmembrane transport
CLI97_RS15375	COG2719	SpoVR family
CLI97_RS15380	COG1785	Belongs to the alkaline phosphatase family
CLI97_RS15385	COG1388	LysM domain
CLI97_RS15385	COG0791	NLP P60 protein
CLI97_RS15390	COG0583	DNA-binding transcription factor activity
CLI97_RS15395	COG0372	Belongs to the citrate synthase family
CLI97_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS15405	COG0531	amino acid
CLI97_RS15410	COG0733	neurotransmitter:sodium symporter activity
CLI97_RS15425	COG1595	DNA-templated transcription, initiation
CLI97_RS15430	COG0204	Acyl-transferase
CLI97_RS15435	COG1253	flavin adenine dinucleotide binding
CLI97_RS15440	COG0789	Transcriptional regulator
CLI97_RS15445	COG0436	Aminotransferase
CLI97_RS15450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLI97_RS15455	COG1253	flavin adenine dinucleotide binding
CLI97_RS15460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLI97_RS15465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLI97_RS15470	COG0584	glycerophosphoryl diester phosphodiesterase
CLI97_RS15480	COG0668	transmembrane transport
CLI97_RS15485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLI97_RS15490	COG0726	polysaccharide deacetylase
CLI97_RS15495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLI97_RS15500	COG3226	Transcriptional regulator
CLI97_RS15510	COG0589	response to stress
CLI97_RS15515	COG1132	(ABC) transporter
CLI97_RS15520	COG1132	(ABC) transporter
CLI97_RS15525	COG0702	epimerase
CLI97_RS15550	COG0189	ligase activity
CLI97_RS15555	COG0189	ligase activity
CLI97_RS15570	COG4335	DNA alkylation repair
CLI97_RS15575	COG0561	phosphatase activity
CLI97_RS15580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLI97_RS15590	COG0475	glutathione-regulated potassium exporter activity
CLI97_RS15595	COG0490	domain, Protein
CLI97_RS15605	COG1024	Enoyl-CoA hydratase
CLI97_RS15615	COG4152	abc transporter atp-binding protein
CLI97_RS15620	COG1668	transmembrane transport
CLI97_RS15625	COG0420	3'-5' exonuclease activity
CLI97_RS15630	COG4717	serine-type aminopeptidase activity
CLI97_RS15645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLI97_RS15685	COG4980	gas vesicle protein
CLI97_RS15700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLI97_RS15705	COG0537	adenosine 5'-monophosphoramidase activity
CLI97_RS15710	COG1131	(ABC) transporter
CLI97_RS15715	COG4473	ABC transporter
CLI97_RS15725	COG1473	amidohydrolase
CLI97_RS15730	COG3069	C4-dicarboxylate transmembrane transporter activity
CLI97_RS15735	COG2329	Antibiotic biosynthesis monooxygenase
CLI97_RS15740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLI97_RS15750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CLI97_RS15755	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CLI97_RS15760	COG1309	transcriptional regulator
CLI97_RS15765	COG1511	domain protein
CLI97_RS15770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLI97_RS15780	COG1363	Peptidase, m42
CLI97_RS15785	COG1301	dicarboxylic acid transport
CLI97_RS15795	COG1234	tRNA 3'-trailer cleavage
CLI97_RS15800	COG0095	Lipoate-protein ligase
CLI97_RS15805	COG0702	epimerase
CLI97_RS15810	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS15820	COG0501	Belongs to the peptidase M48B family
CLI97_RS15825	COG1404	Belongs to the peptidase S8 family
CLI97_RS15835	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CLI97_RS15840	COG0406	alpha-ribazole phosphatase activity
CLI97_RS15845	COG0183	Belongs to the thiolase family
CLI97_RS15850	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS15855	COG1268	BioY protein
CLI97_RS15860	COG0840	transmembrane signaling receptor activity
CLI97_RS15865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLI97_RS15865	COG0723	plastoquinol--plastocyanin reductase activity
CLI97_RS15870	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS15880	COG4903	ComK protein
CLI97_RS15890	COG5646	InterPro IPR014922
CLI97_RS15910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLI97_RS15925	COG0398	Pfam SNARE associated Golgi protein
CLI97_RS15930	COG0681	Belongs to the peptidase S26 family
CLI97_RS15935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI97_RS15940	COG1846	Transcriptional regulator
CLI97_RS15945	COG3180	Ammonia monooxygenase
CLI97_RS15950	COG2814	Major facilitator Superfamily
CLI97_RS15960	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CLI97_RS15965	COG2323	membrane
CLI97_RS15980	COG0420	3'-5' exonuclease activity
CLI97_RS15985	COG0419	ATPase involved in DNA repair
CLI97_RS15990	COG1403	HNH endonuclease
CLI97_RS16030	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLI97_RS16050	COG0367	asparagine synthase
CLI97_RS16055	COG1562	ergosterol biosynthetic process
CLI97_RS16060	COG0534	Mate efflux family protein
CLI97_RS16065	COG1917	Cupin 2, conserved barrel domain protein
CLI97_RS16065	COG2207	Transcriptional regulator
CLI97_RS16070	COG1609	Transcriptional regulator
CLI97_RS16075	COG0673	inositol 2-dehydrogenase activity
CLI97_RS16080	COG2318	DinB family
CLI97_RS16085	COG1279	arginine transmembrane transporter activity
CLI97_RS16090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLI97_RS16095	COG1357	PFAM Pentapeptide repeats (8 copies)
CLI97_RS16100	COG2153	protein acetylation
CLI97_RS16105	COG0646	methionine synthase
CLI97_RS16105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLI97_RS16115	COG2996	Protein conserved in bacteria
CLI97_RS16120	COG1744	ABC transporter substrate-binding protein PnrA-like
CLI97_RS16125	COG0840	transmembrane signaling receptor activity
CLI97_RS16135	COG1307	EDD domain protein, DegV family
CLI97_RS16140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLI97_RS16155	COG0561	phosphatase activity
CLI97_RS16160	COG1073	alpha beta
CLI97_RS16165	COG2151	metal-sulfur cluster biosynthetic enzyme
CLI97_RS16175	COG0277	FAD linked oxidase domain protein
CLI97_RS16180	COG2271	Major facilitator Superfamily
CLI97_RS16190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLI97_RS16200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLI97_RS16205	COG0505	Belongs to the CarA family
CLI97_RS16210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLI97_RS16215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLI97_RS16235	COG2267	carboxylic ester hydrolase activity
CLI97_RS16245	COG1744	ABC transporter substrate-binding protein PnrA-like
CLI97_RS16260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLI97_RS16265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLI97_RS16270	COG5504	Zn-dependent protease
CLI97_RS16275	COG0444	Belongs to the ABC transporter superfamily
CLI97_RS16280	COG4608	Belongs to the ABC transporter superfamily
CLI97_RS16290	COG0601	transmembrane transport
CLI97_RS16295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI97_RS16305	COG0180	Tryptophanyl-tRNA synthetase
CLI97_RS16310	COG4166	transmembrane transport
CLI97_RS16315	COG0601	transmembrane transport
CLI97_RS16320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI97_RS16325	COG0444	Belongs to the ABC transporter superfamily
CLI97_RS16330	COG4608	Belongs to the ABC transporter superfamily
CLI97_RS16340	COG0456	acetyltransferase
CLI97_RS16345	COG1393	Belongs to the ArsC family
CLI97_RS16350	COG0861	Integral membrane protein TerC family
CLI97_RS16355	COG4862	establishment of competence for transformation
CLI97_RS16360	COG4469	Competence protein
CLI97_RS16365	COG1164	Oligoendopeptidase f
CLI97_RS16375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CLI97_RS16380	COG2346	COG2346, Truncated hemoglobins
CLI97_RS16385	COG0741	lytic transglycosylase activity
CLI97_RS16390	COG4116	CYTH
CLI97_RS16400	COG2357	RelA SpoT domain protein
CLI97_RS16405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLI97_RS16410	COG0564	pseudouridine synthase activity
CLI97_RS16420	COG0569	domain protein
CLI97_RS16420	COG0475	glutathione-regulated potassium exporter activity
CLI97_RS16425	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CLI97_RS16430	COG0352	thiamine-phosphate diphosphorylase activity
CLI97_RS16435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLI97_RS16440	COG2104	thiamine diphosphate biosynthetic process
CLI97_RS16450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLI97_RS16455	COG0351	phosphomethylpyrimidine kinase
CLI97_RS16460	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLI97_RS16515	COG0210	DNA helicase
CLI97_RS16535	COG1131	(ABC) transporter
CLI97_RS16545	COG2153	protein acetylation
CLI97_RS16555	COG2382	esterase
CLI97_RS16560	COG0626	cystathionine gamma-synthase activity
CLI97_RS16565	COG0626	cystathionine gamma-synthase activity
CLI97_RS16615	COG5444	nuclease activity
CLI97_RS16645	COG5444	nuclease activity
CLI97_RS16670	COG5444	nuclease activity
CLI97_RS16680	COG2367	Beta-lactamase
CLI97_RS16685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CLI97_RS16695	COG1846	Transcriptional regulator
CLI97_RS16705	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CLI97_RS16710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLI97_RS16715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CLI97_RS16720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLI97_RS16720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLI97_RS16725	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLI97_RS16735	COG1349	DNA-binding transcription factor activity
CLI97_RS16750	COG1285	pathogenesis
CLI97_RS16765	COG2205	protein histidine kinase activity
CLI97_RS16775	COG3383	formate dehydrogenase (NAD+) activity
CLI97_RS16780	COG2427	Protein of unknown function (DUF1641)
CLI97_RS16785	COG2124	cytochrome p450
CLI97_RS16790	COG1819	glycosyl
CLI97_RS16800	COG1587	Uroporphyrinogen-III synthase
CLI97_RS16805	COG0390	transport system, permease component
CLI97_RS16810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLI97_RS16815	COG0697	spore germination
CLI97_RS16820	COG4297	protein containing double-stranded beta helix domain
CLI97_RS16830	COG1252	NADH dehydrogenase
CLI97_RS16840	COG2211	Major facilitator Superfamily
CLI97_RS16845	COG1609	Transcriptional regulator
CLI97_RS16850	COG0246	Mannitol dehydrogenase
CLI97_RS16855	COG2721	sulfolactate sulfo-lyase activity
CLI97_RS16860	COG0730	response to heat
CLI97_RS16865	COG2318	DinB family
CLI97_RS16870	COG0457	Tetratricopeptide repeat
CLI97_RS16880	COG5632	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS16880	COG3409	Peptidoglycan-binding domain 1 protein
CLI97_RS16880	COG1388	LysM domain
CLI97_RS16890	COG4195	phage-related replication protein
CLI97_RS16895	COG2856	Zn peptidase
CLI97_RS16900	COG1396	sequence-specific DNA binding
CLI97_RS16910	COG1522	sequence-specific DNA binding
CLI97_RS16915	COG1484	DNA-dependent DNA replication
CLI97_RS16935	COG1595	DNA-templated transcription, initiation
CLI97_RS16940	COG5484	DNA packaging
CLI97_RS16940	COG3728	DNA packaging
CLI97_RS16945	COG1783	phage Terminase large subunit
CLI97_RS16950	COG5518	Phage portal protein
CLI97_RS16955	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CLI97_RS16960	COG4653	Phage capsid family
CLI97_RS17010	COG3953	SLT domain
CLI97_RS17010	COG5412	phage tail tape measure protein
CLI97_RS17010	COG3953	SLT domain
CLI97_RS17010	COG5412	phage tail tape measure protein
CLI97_RS17010	COG3953	SLT domain
CLI97_RS17010	COG5412	phage tail tape measure protein
CLI97_RS17015	COG1652	LysM domain
CLI97_RS17020	COG4193	domain, Protein
CLI97_RS17030	COG3628	GPW Gp25 family protein
CLI97_RS17035	COG3299	homolog of phage Mu protein gp47
CLI97_RS17040	COG3778	Protein conserved in bacteria
CLI97_RS17080	COG3409	Peptidoglycan-binding domain 1 protein
CLI97_RS17080	COG5632	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS17095	COG0306	phosphate transporter
CLI97_RS17100	COG1392	Phosphate transport regulator
CLI97_RS17105	COG0531	amino acid
CLI97_RS17110	COG0346	lactoylglutathione lyase activity
CLI97_RS17115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLI97_RS17120	COG0463	Glycosyl transferase, family 2
CLI97_RS17125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLI97_RS17130	COG0477	Major facilitator Superfamily
CLI97_RS17135	COG2362	D-Aminopeptidase
CLI97_RS17140	COG0601	transmembrane transport
CLI97_RS17145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI97_RS17150	COG0444	Belongs to the ABC transporter superfamily
CLI97_RS17155	COG4166	transmembrane transport
CLI97_RS17160	COG1619	proteins homologs of microcin C7 resistance protein MccF
CLI97_RS17165	COG4948	Mandelate Racemase Muconate Lactonizing
CLI97_RS17170	COG0791	NLP P60 protein
CLI97_RS17175	COG4608	Belongs to the ABC transporter superfamily
CLI97_RS17180	COG2706	6-phosphogluconolactonase activity
CLI97_RS17185	COG1834	amidinotransferase
CLI97_RS17190	COG1607	acyl-coa hydrolase
CLI97_RS17195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI97_RS17200	COG2076	Multidrug Resistance protein
CLI97_RS17205	COG2076	Multidrug Resistance protein
CLI97_RS17210	COG0788	formyltetrahydrofolate deformylase activity
CLI97_RS17215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLI97_RS17225	COG1764	response to oxidative stress
CLI97_RS17230	COG1846	Transcriptional regulator
CLI97_RS17235	COG1764	response to oxidative stress
CLI97_RS17250	COG0457	Tetratricopeptide repeat
CLI97_RS17250	COG0463	Glycosyl transferase, family 2
CLI97_RS17265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLI97_RS17275	COG1404	Belongs to the peptidase S8 family
CLI97_RS17280	COG1366	Belongs to the anti-sigma-factor antagonist family
CLI97_RS17285	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLI97_RS17290	COG1122	ATPase activity
CLI97_RS17295	COG4721	ABC-type cobalt transport system, permease component
CLI97_RS17300	COG1388	LysM domain
CLI97_RS17300	COG3858	chitin binding
CLI97_RS17315	COG2239	Acts as a magnesium transporter
CLI97_RS17320	COG0789	Transcriptional regulator
CLI97_RS17335	COG1846	Transcriptional regulator
CLI97_RS17340	COG0726	polysaccharide deacetylase
CLI97_RS17345	COG1793	dna ligase
CLI97_RS17345	COG3285	dna ligase
CLI97_RS17350	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CLI97_RS17360	COG0586	Pfam SNARE associated Golgi protein
CLI97_RS17365	COG0861	Integral membrane protein TerC family
CLI97_RS17370	COG1191	sigma factor activity
CLI97_RS17395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLI97_RS17400	COG2323	membrane
CLI97_RS17410	COG3594	Acyltransferase
CLI97_RS17415	COG5002	protein histidine kinase activity
CLI97_RS17420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLI97_RS17435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLI97_RS17440	COG0436	Aminotransferase
CLI97_RS17470	COG3852	Histidine kinase
CLI97_RS17475	COG1846	Transcriptional regulator
CLI97_RS17480	COG1360	Flagellar Motor Protein
CLI97_RS17485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLI97_RS17490	COG0542	response to heat
CLI97_RS17500	COG3949	Membrane
CLI97_RS17515	COG0720	synthase
CLI97_RS17520	COG0602	queuosine metabolic process
CLI97_RS17570	COG4873	Protein conserved in bacteria
CLI97_RS17580	COG3773	Cell wall hydrolase
CLI97_RS17585	COG2244	polysaccharide biosynthetic process
CLI97_RS17590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS17595	COG2217	Heavy metal translocating P-type atpase
CLI97_RS17600	COG0006	proline dipeptidase activity
CLI97_RS17605	COG1609	Transcriptional regulator
CLI97_RS17610	COG3711	transcriptional antiterminator
CLI97_RS17615	COG1263	PTS System
CLI97_RS17615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI97_RS17615	COG2190	(PTS) system
CLI97_RS17620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI97_RS17625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLI97_RS17635	COG1533	DNA photolyase activity
CLI97_RS17640	COG0840	transmembrane signaling receptor activity
CLI97_RS17645	COG2084	Dehydrogenase
CLI97_RS17655	COG0347	Belongs to the P(II) protein family
CLI97_RS17660	COG2340	Cysteine-rich secretory protein family
CLI97_RS17665	COG0768	penicillin binding
CLI97_RS17670	COG4191	Histidine kinase
CLI97_RS17675	COG0436	Aminotransferase
CLI97_RS17690	COG0835	chemotaxis
CLI97_RS17690	COG0784	Response regulator, receiver
CLI97_RS17700	COG2814	Major facilitator Superfamily
CLI97_RS17705	COG1376	ErfK ybiS ycfS ynhG family protein
CLI97_RS17710	COG1408	metallophosphoesterase
CLI97_RS17715	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS17725	COG2200	EAL domain
CLI97_RS17730	COG4703	Protein of unknown function (DUF1797)
CLI97_RS17735	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CLI97_RS17745	COG0517	IMP dehydrogenase activity
CLI97_RS17750	COG0583	DNA-binding transcription factor activity
CLI97_RS17755	COG0716	FMN binding
CLI97_RS17765	COG0716	FMN binding
CLI97_RS17785	COG0668	transmembrane transport
CLI97_RS17790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS17810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLI97_RS17815	COG0303	'Molybdopterin
CLI97_RS17820	COG1763	Mo-molybdopterin cofactor biosynthetic process
CLI97_RS17825	COG0314	molybdopterin synthase activity
CLI97_RS17830	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CLI97_RS17840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLI97_RS17845	COG1136	(ABC) transporter
CLI97_RS17850	COG0577	efflux transmembrane transporter activity
CLI97_RS17855	COG1349	DNA-binding transcription factor activity
CLI97_RS17860	COG1105	Belongs to the carbohydrate kinase PfkB family
CLI97_RS17865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI97_RS17865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI97_RS17865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI97_RS17870	COG0681	Belongs to the peptidase S26 family
CLI97_RS17880	COG0488	(ABC) transporter
CLI97_RS17885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLI97_RS17890	COG2309	aminopeptidase activity
CLI97_RS17900	COG1077	Cell shape determining protein MreB Mrl
CLI97_RS17910	COG2002	toxin-antitoxin pair type II binding
CLI97_RS17915	COG3852	Histidine kinase
CLI97_RS17920	COG2105	PFAM AIG2 family protein
CLI97_RS17920	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CLI97_RS17925	COG0569	domain protein
CLI97_RS17935	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLI97_RS17950	COG0561	phosphatase activity
CLI97_RS17955	COG0242	peptide deformylase activity
CLI97_RS17965	COG0497	DNA recombination
CLI97_RS17980	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS17980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS17980	COG3321	synthase
CLI97_RS17980	COG4221	oxidoreductase activity
CLI97_RS17985	COG4221	oxidoreductase activity
CLI97_RS17985	COG0300	oxidoreductase activity
CLI97_RS17985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS17985	COG3321	synthase
CLI97_RS17990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS17990	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS17990	COG3321	synthase
CLI97_RS17990	COG4221	oxidoreductase activity
CLI97_RS17995	COG4221	oxidoreductase activity
CLI97_RS17995	COG0300	oxidoreductase activity
CLI97_RS17995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS17995	COG3321	synthase
CLI97_RS18000	COG3321	synthase
CLI97_RS18000	COG0300	oxidoreductase activity
CLI97_RS18000	COG4221	oxidoreductase activity
CLI97_RS18000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS18005	COG3321	synthase
CLI97_RS18005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS18005	COG4221	oxidoreductase activity
CLI97_RS18005	COG0300	oxidoreductase activity
CLI97_RS18010	COG3321	synthase
CLI97_RS18010	COG4221	oxidoreductase activity
CLI97_RS18010	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS18010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS18015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLI97_RS18020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CLI97_RS18025	COG0022	dehydrogenase e1 component
CLI97_RS18030	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLI97_RS18035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI97_RS18040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS18055	COG1982	Orn Lys Arg decarboxylase major
CLI97_RS18080	COG0483	inositol monophosphate 1-phosphatase activity
CLI97_RS18090	COG3227	Zinc metalloprotease (Elastase)
CLI97_RS18105	COG1595	DNA-templated transcription, initiation
CLI97_RS18125	COG1217	gtp-binding protein TYPA
CLI97_RS18135	COG4896	Protein conserved in bacteria
CLI97_RS18145	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CLI97_RS18150	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CLI97_RS18155	COG2066	Belongs to the glutaminase family
CLI97_RS18165	COG0772	Belongs to the SEDS family
CLI97_RS18170	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CLI97_RS18185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLI97_RS18185	COG2010	Cytochrome c
CLI97_RS18190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLI97_RS18195	COG1845	cytochrome c oxidase, subunit III
CLI97_RS18200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CLI97_RS18205	COG3336	cytochrome c oxidase
CLI97_RS18215	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CLI97_RS18220	COG2340	Cysteine-rich secretory protein family
CLI97_RS18235	COG3679	Belongs to the UPF0342 family
CLI97_RS18250	COG0742	ribosomal rna small subunit methyltransferase
CLI97_RS18260	COG3314	Sporulation integral membrane protein YlbJ
CLI97_RS18265	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLI97_RS18270	COG3480	Lon protease (S16) C-terminal proteolytic domain
CLI97_RS18280	COG1399	metal-binding, possibly nucleic acid-binding protein
CLI97_RS18300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLI97_RS18320	COG4839	cell division protein FtsL
CLI97_RS18325	COG0768	penicillin binding
CLI97_RS18330	COG0768	penicillin binding
CLI97_RS18350	COG0772	Belongs to the SEDS family
CLI97_RS18365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CLI97_RS18370	COG0849	cell division
CLI97_RS18375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLI97_RS18380	COG4412	M6 family metalloprotease domain protein
CLI97_RS18380	COG1404	Belongs to the peptidase S8 family
CLI97_RS18390	COG1191	sigma factor activity
CLI97_RS18395	COG1191	sigma factor activity
CLI97_RS18400	COG1119	ATPase activity
CLI97_RS18405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLI97_RS18410	COG1873	PFAM PRC-barrel domain
CLI97_RS18415	COG1496	oxidoreductase activity
CLI97_RS18420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLI97_RS18430	COG0762	integral membrane protein
CLI97_RS18435	COG2302	S4 RNA-binding domain
CLI97_RS18440	COG3599	regulation of cell shape
CLI97_RS18450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLI97_RS18455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CLI97_RS18465	COG0564	pseudouridine synthase activity
CLI97_RS18475	COG2233	PERMEase
CLI97_RS18485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLI97_RS18490	COG0505	Belongs to the CarA family
CLI97_RS18495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLI97_RS18510	COG0284	orotidine-5'-phosphate decarboxylase activity
CLI97_RS18515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLI97_RS18525	COG0306	phosphate transporter
CLI97_RS18540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLI97_RS18545	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CLI97_RS18550	COG1648	precorrin-2 dehydrogenase activity
CLI97_RS18565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLI97_RS18570	COG1561	YicC-like family, N-terminal region
CLI97_RS18580	COG0194	GDP metabolic process
CLI97_RS18590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLI97_RS18595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLI97_RS18600	COG0242	peptide deformylase activity
CLI97_RS18610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLI97_RS18610	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLI97_RS18620	COG0631	protein serine/threonine phosphatase activity
CLI97_RS18625	COG0515	serine threonine protein kinase
CLI97_RS18625	COG2815	serine threonine protein kinase
CLI97_RS18635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLI97_RS18640	COG1564	THIamine pyrophosphokinase
CLI97_RS18655	COG1302	Protein conserved in bacteria
CLI97_RS18660	COG1461	Dihydroxyacetone kinase
CLI97_RS18665	COG1760	l-serine dehydratase
CLI97_RS18670	COG1760	l-serine dehydratase
CLI97_RS18675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLI97_RS18690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLI97_RS18695	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS18710	COG1196	nuclear chromosome segregation
CLI97_RS18715	COG0552	protein localization to endoplasmic reticulum
CLI97_RS18730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLI97_RS18740	COG1837	Belongs to the UPF0109 family
CLI97_RS18765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CLI97_RS18780	COG2257	FlhB HrpN YscU SpaS Family
CLI97_RS18790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CLI97_RS18795	COG0758	DNA mediated transformation
CLI97_RS18800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLI97_RS18810	COG4974	Belongs to the 'phage' integrase family
CLI97_RS18830	COG1815	bacterial-type flagellum-dependent cell motility
CLI97_RS18835	COG1558	bacterial-type flagellum-dependent cell motility
CLI97_RS18840	COG1677	Flagellar hook-basal body complex protein FliE
CLI97_RS18845	COG1766	The M ring may be actively involved in energy transduction
CLI97_RS18850	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLI97_RS18855	COG1317	bacterial-type flagellum organization
CLI97_RS18860	COG1157	protein secretion by the type III secretion system
CLI97_RS18865	COG2882	bacterial-type flagellum organization
CLI97_RS18870	COG3334	PFAM MgtE intracellular
CLI97_RS18875	COG3144	bacterial-type flagellum assembly
CLI97_RS18880	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CLI97_RS18885	COG4786	Flagellar basal body rod
CLI97_RS18890	COG1582	Flagellar protein (FlbD)
CLI97_RS18895	COG1580	Controls the rotational direction of flagella during chemotaxis
CLI97_RS18900	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLI97_RS18905	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLI97_RS18905	COG1776	CheC inhibitor of MCP methylation
CLI97_RS18910	COG2201	protein-glutamate methylesterase activity
CLI97_RS18915	COG3190	flagellar
CLI97_RS18920	COG1338	Plays a role in the flagellum-specific transport system
CLI97_RS18925	COG1987	bacterial-type flagellum assembly
CLI97_RS18930	COG1684	flagellar biosynthetic protein fliR
CLI97_RS18935	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLI97_RS18940	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLI97_RS18945	COG1419	protein localization to endoplasmic reticulum
CLI97_RS18950	COG0455	bacterial-type flagellum organization
CLI97_RS18955	COG2201	protein-glutamate methylesterase activity
CLI97_RS18960	COG2198	Histidine kinase
CLI97_RS18960	COG0643	Histidine kinase
CLI97_RS18965	COG0835	chemotaxis
CLI97_RS18970	COG1776	CheC inhibitor of MCP methylation
CLI97_RS18980	COG1191	sigma factor activity
CLI97_RS19010	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLI97_RS19015	COG4589	Belongs to the CDS family
CLI97_RS19025	COG0750	zinc metalloprotease
CLI97_RS19035	COG2176	DNA-directed DNA polymerase activity
CLI97_RS19045	COG0195	Participates in both transcription termination and antitermination
CLI97_RS19050	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CLI97_RS19055	COG1358	cellular component organization or biogenesis
CLI97_RS19065	COG1550	Protein conserved in bacteria
CLI97_RS19080	COG0196	riboflavin kinase activity
CLI97_RS19095	COG0726	polysaccharide deacetylase
CLI97_RS19100	COG0612	Peptidase, M16
CLI97_RS19105	COG1873	PFAM PRC-barrel domain
CLI97_RS19110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLI97_RS19115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLI97_RS19120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLI97_RS19125	COG0527	aspartate kinase activity
CLI97_RS19135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLI97_RS19140	COG0740	serine-type endopeptidase activity
CLI97_RS19150	COG4980	gas vesicle protein
CLI97_RS19150	COG1674	ftsk spoiiie
CLI97_RS19155	COG2188	Transcriptional regulator
CLI97_RS19160	COG2814	Major facilitator Superfamily
CLI97_RS19165	COG1846	Transcriptional regulator
CLI97_RS19170	COG2409	Drug exporters of the RND superfamily
CLI97_RS19170	COG1033	growth of symbiont in host cell
CLI97_RS19175	COG0612	Peptidase, M16
CLI97_RS19180	COG0612	Peptidase, M16
CLI97_RS19185	COG0300	oxidoreductase activity
CLI97_RS19200	COG1426	Protein conserved in bacteria
CLI97_RS19205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLI97_RS19220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLI97_RS19230	COG1692	metallophosphoesterase
CLI97_RS19235	COG2359	stage V sporulation protein S
CLI97_RS19255	COG4550	Control of competence regulator ComK, YlbF/YmcA
CLI97_RS19305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS19310	COG3425	synthase
CLI97_RS19315	COG1024	Enoyl-CoA hydratase
CLI97_RS19320	COG1024	Enoyl-CoA hydratase
CLI97_RS19325	COG0300	oxidoreductase activity
CLI97_RS19325	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS19325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS19325	COG3321	synthase
CLI97_RS19325	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS19330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS19330	COG3321	synthase
CLI97_RS19330	COG4221	oxidoreductase activity
CLI97_RS19330	COG0300	oxidoreductase activity
CLI97_RS19335	COG3321	synthase
CLI97_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS19335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS19335	COG3321	synthase
CLI97_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS19335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS19335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI97_RS19335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS19335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS19335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI97_RS19340	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS19340	COG3321	synthase
CLI97_RS19340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS19340	COG4221	oxidoreductase activity
CLI97_RS19345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI97_RS19345	COG3321	synthase
CLI97_RS19345	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CLI97_RS19345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLI97_RS19350	COG2124	cytochrome p450
CLI97_RS19355	COG3209	COG3209 Rhs family protein
CLI97_RS19360	COG3619	membrane
CLI97_RS19370	COG1404	Belongs to the peptidase S8 family
CLI97_RS19380	COG4195	phage-related replication protein
CLI97_RS19385	COG1764	response to oxidative stress
CLI97_RS19395	COG2076	Multidrug Resistance protein
CLI97_RS19435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI97_RS19440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI97_RS19445	COG4112	unkown
CLI97_RS19450	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLI97_RS19460	COG0464	growth
CLI97_RS19465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLI97_RS19470	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CLI97_RS19475	COG0789	Transcriptional regulator
CLI97_RS19480	COG0174	glutamine synthetase
CLI97_RS19495	COG2211	Major facilitator Superfamily
CLI97_RS19500	COG3507	Belongs to the glycosyl hydrolase 43 family
CLI97_RS19515	COG1070	Carbohydrate kinase
CLI97_RS19520	COG0574	Belongs to the PEP-utilizing enzyme family
CLI97_RS19520	COG3848	Pyruvate phosphate dikinase
CLI97_RS19545	COG1064	alcohol dehydrogenase
CLI97_RS19555	COG0456	acetyltransferase
CLI97_RS19580	COG3397	chitin binding
CLI97_RS19595	COG5434	Belongs to the glycosyl hydrolase 28 family
CLI97_RS19600	COG0756	dUTP diphosphatase activity
CLI97_RS19605	COG4195	phage-related replication protein
CLI97_RS19635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLI97_RS19645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLI97_RS19665	COG0785	Cytochrome C biogenesis protein
CLI97_RS19670	COG2201	protein-glutamate methylesterase activity
CLI97_RS19675	COG4846	Membrane protein involved in cytochrome C biogenesis
CLI97_RS19685	COG0071	Belongs to the small heat shock protein (HSP20) family
CLI97_RS19700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLI97_RS19705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS19725	COG0824	Thioesterase
CLI97_RS19735	COG4841	protein insertion into membrane
CLI97_RS19745	COG1832	CoA-binding protein
CLI97_RS19750	COG0187	DNA topoisomerase II activity
CLI97_RS19755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLI97_RS19765	COG1115	amino acid carrier protein
CLI97_RS19775	COG1063	alcohol dehydrogenase
CLI97_RS19780	COG0800	Aldolase
CLI97_RS19785	COG1312	Catalyzes the dehydration of D-mannonate
CLI97_RS19790	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS19795	COG1609	Transcriptional regulator
CLI97_RS19800	COG2271	Major facilitator Superfamily
CLI97_RS19860	COG3507	Belongs to the glycosyl hydrolase 43 family
CLI97_RS19885	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS19890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLI97_RS19895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CLI97_RS19900	COG2610	gluconate transmembrane transporter activity
CLI97_RS19905	COG2124	cytochrome p450
CLI97_RS19925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLI97_RS19935	COG2246	polysaccharide biosynthetic process
CLI97_RS19940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLI97_RS19945	COG0586	Pfam SNARE associated Golgi protein
CLI97_RS19950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLI97_RS19955	COG1024	Enoyl-CoA hydratase
CLI97_RS19960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLI97_RS19965	COG0511	ligase activity, forming carbon-carbon bonds
CLI97_RS19970	COG0439	Biotin carboxylase
CLI97_RS19975	COG0318	PFAM AMP-dependent synthetase and ligase
CLI97_RS19980	COG1960	acyl-CoA dehydrogenase activity
CLI97_RS19985	COG1649	PFAM Uncharacterised BCR, COG1649
CLI97_RS19995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS19995	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CLI97_RS20000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS20005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS20010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS20015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI97_RS20025	COG2027	D-alanyl-D-alanine carboxypeptidase
CLI97_RS20030	COG2017	converts alpha-aldose to the beta-anomer
CLI97_RS20035	COG0534	Mate efflux family protein
CLI97_RS20050	COG0582	viral genome integration into host DNA
CLI97_RS20055	COG0166	Belongs to the GPI family
CLI97_RS20060	COG0405	Gamma-glutamyltransferase
CLI97_RS20065	COG2814	Major facilitator Superfamily
CLI97_RS20070	COG0640	Transcriptional regulator
CLI97_RS20075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLI97_RS20085	COG0604	alcohol dehydrogenase
CLI97_RS20090	COG0493	'glutamate synthase
CLI97_RS20095	COG0067	glutamate synthase
CLI97_RS20095	COG0070	glutamate synthase
CLI97_RS20095	COG0069	glutamate synthase activity
CLI97_RS20100	COG0583	DNA-binding transcription factor activity
CLI97_RS20105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLI97_RS20120	COG0300	oxidoreductase activity
CLI97_RS20125	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CLI97_RS20135	COG2814	Major facilitator Superfamily
CLI97_RS20140	COG1070	Carbohydrate kinase
CLI97_RS20145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLI97_RS20150	COG0243	molybdopterin cofactor binding
CLI97_RS20170	COG1028	Short-chain dehydrogenase reductase Sdr
CLI97_RS20175	COG1733	regulation of RNA biosynthetic process
CLI97_RS20180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI97_RS20185	COG2207	Transcriptional regulator
CLI97_RS20185	COG0662	Cupin 2, conserved barrel domain protein
CLI97_RS20190	COG1309	transcriptional regulator
CLI97_RS20195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI97_RS20205	COG0640	Transcriptional regulator
CLI97_RS20210	COG0741	lytic transglycosylase activity
CLI97_RS20215	COG2322	membrane
CLI97_RS20230	COG1619	proteins homologs of microcin C7 resistance protein MccF
CLI97_RS20240	COG3584	3D domain protein
CLI97_RS20240	COG1388	LysM domain
CLI97_RS20245	COG0514	ATP-dependent DNA helicase (RecQ)
CLI97_RS20255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLI97_RS20260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CLI97_RS20275	COG0071	Belongs to the small heat shock protein (HSP20) family
CLI97_RS20305	COG1012	belongs to the aldehyde dehydrogenase family
CLI97_RS20310	COG1657	PFAM Prenyltransferase squalene oxidase
CLI97_RS20315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLI97_RS20320	COG0733	neurotransmitter:sodium symporter activity
CLI97_RS20325	COG0385	Bile acid
CLI97_RS20330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI97_RS20335	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLI97_RS20345	COG4548	von Willebrand factor, type A
CLI97_RS20350	COG0714	Associated with various cellular activities
CLI97_RS20355	COG2032	superoxide dismutase activity
CLI97_RS20360	COG1388	LysM domain
CLI97_RS20360	COG0791	NLP P60 protein
CLI97_RS20365	COG1819	glycosyl
CLI97_RS20370	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CLI97_RS20375	COG0534	Mate efflux family protein
CLI97_RS20380	COG1366	Belongs to the anti-sigma-factor antagonist family
CLI97_RS20385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLI97_RS20390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLI97_RS20400	COG2962	Rard protein
CLI97_RS20415	COG1942	4-Oxalocrotonate Tautomerase
CLI97_RS20425	COG1733	regulation of RNA biosynthetic process
CLI97_RS20430	COG0778	Nitroreductase
CLI97_RS20435	COG0400	carboxylic ester hydrolase activity
CLI97_RS20440	COG0346	lactoylglutathione lyase activity
CLI97_RS20450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLI97_RS20460	COG2723	6-phospho-beta-galactosidase activity
CLI97_RS20465	COG2188	Transcriptional regulator
CLI97_RS20470	COG0793	Belongs to the peptidase S41A family
CLI97_RS20470	COG3409	Peptidoglycan-binding domain 1 protein
CLI97_RS20475	COG2226	methyltransferase
CLI97_RS20485	COG1876	peptidase activity
CLI97_RS20505	COG0671	phosphoesterase, PA-phosphatase related
CLI97_RS20545	COG2337	Toxic component of a toxin-antitoxin (TA) module
CLI97_RS20550	COG3331	DNA recombination
CLI97_RS20625	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLI97_RS20630	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLI97_RS20650	COG4112	unkown
CLI97_RS20655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI97_RS20660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI97_RS20670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI97_RS20675	COG1780	Probably involved in ribonucleotide reductase function