locus-tag	class	description
MID02_RS00010	COG0592	DNA-directed DNA polymerase activity
MID02_RS00015	COG2501	S4 domain
MID02_RS00030	COG0187	DNA topoisomerase II activity
MID02_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MID02_RS00070	COG0516	GMP reductase activity
MID02_RS00070	COG0517	IMP dehydrogenase activity
MID02_RS00075	COG1686	Belongs to the peptidase S11 family
MID02_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
MID02_RS00105	COG1428	Deoxynucleoside kinase
MID02_RS00110	COG1428	Deoxynucleoside kinase
MID02_RS00115	COG1388	LysM domain
MID02_RS00115	COG3858	chitin binding
MID02_RS00120	COG1335	isochorismatase
MID02_RS00125	COG0590	tRNA wobble adenosine to inosine editing
MID02_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MID02_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MID02_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MID02_RS00195	COG3853	Toxic anion resistance protein (TelA)
MID02_RS00200	COG1982	Orn Lys Arg decarboxylase major
MID02_RS00210	COG3870	Protein conserved in bacteria
MID02_RS00215	COG1728	Protein conserved in bacteria
MID02_RS00220	COG0470	DNA polymerase III
MID02_RS00225	COG1774	PSP1 C-terminal conserved region
MID02_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MID02_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MID02_RS00250	COG2002	toxin-antitoxin pair type II binding
MID02_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID02_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID02_RS00260	COG0084	hydrolase, TatD family'
MID02_RS00265	COG3584	3D domain protein
MID02_RS00265	COG3583	domain protein
MID02_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MID02_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MID02_RS00285	COG4466	Protein conserved in bacteria
MID02_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MID02_RS00305	COG0251	oxidation-reduction process
MID02_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MID02_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MID02_RS00345	COG2002	toxin-antitoxin pair type II binding
MID02_RS00350	COG2244	polysaccharide biosynthetic process
MID02_RS00355	COG3956	TIGRFAM MazG family protein
MID02_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MID02_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MID02_RS00380	COG1098	S1 RNA binding domain
MID02_RS00395	COG2208	phosphoserine phosphatase activity
MID02_RS00400	COG2304	oxidoreductase activity
MID02_RS00405	COG0515	serine threonine protein kinase
MID02_RS00410	COG0037	tRNA processing
MID02_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MID02_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MID02_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MID02_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MID02_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MID02_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
MID02_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MID02_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MID02_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MID02_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MID02_RS00475	COG1396	sequence-specific DNA binding
MID02_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MID02_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MID02_RS00565	COG4463	regulation of RNA biosynthetic process
MID02_RS00570	COG3880	PFAM UvrB UvrC protein
MID02_RS00580	COG0542	response to heat
MID02_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MID02_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MID02_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
MID02_RS00615	COG1045	serine acetyltransferase
MID02_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MID02_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MID02_RS00635	COG3688	RNA-binding protein containing a PIN domain
MID02_RS00640	COG1595	DNA-templated transcription, initiation
MID02_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MID02_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
MID02_RS00680	COG2813	Specifically methylates the guanine in position
MID02_RS00695	COG1358	cellular component organization or biogenesis
MID02_RS00720	COG0596	Alpha beta hydrolase
MID02_RS00830	COG0201	protein transport
MID02_RS00840	COG0024	Methionine aminopeptidase
MID02_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MID02_RS00880	COG1122	ATPase activity
MID02_RS00885	COG1122	ATPase activity
MID02_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MID02_RS00910	COG2226	methyltransferase
MID02_RS00915	COG2318	DinB family
MID02_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
MID02_RS00930	COG0489	protein tyrosine kinase activity
MID02_RS00940	COG2194	sulfuric ester hydrolase activity
MID02_RS00945	COG0726	polysaccharide deacetylase
MID02_RS01005	COG0738	Major facilitator superfamily
MID02_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MID02_RS01020	COG1063	alcohol dehydrogenase
MID02_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
MID02_RS01030	COG0385	Bile acid
MID02_RS01035	COG2819	hydrolase of the alpha beta superfamily
MID02_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID02_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID02_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MID02_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MID02_RS01055	COG2207	Transcriptional regulator
MID02_RS01060	COG3876	Protein conserved in bacteria
MID02_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
MID02_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MID02_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID02_RS01075	COG1263	PTS System
MID02_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MID02_RS01090	COG1683	Conserved Protein
MID02_RS01120	COG1595	DNA-templated transcription, initiation
MID02_RS01125	COG5662	AntiSigma factor
MID02_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MID02_RS01135	COG4856	YbbR-like protein
MID02_RS01185	COG1346	cytolysis
MID02_RS01190	COG1380	Effector of murein hydrolase LrgA
MID02_RS01195	COG1846	Transcriptional regulator
MID02_RS01200	COG1113	amino acid transport
MID02_RS01205	COG1011	Hydrolase
MID02_RS01210	COG4585	Histidine kinase
MID02_RS01215	COG2197	response regulator
MID02_RS01220	COG1131	(ABC) transporter
MID02_RS01260	COG0531	amino acid
MID02_RS01265	COG0584	glycerophosphoryl diester phosphodiesterase
MID02_RS01270	COG2271	Major facilitator Superfamily
MID02_RS01280	COG2368	4-hydroxyphenylacetate
MID02_RS01290	COG3409	Peptidoglycan-binding domain 1 protein
MID02_RS01305	COG0371	Dehydrogenase
MID02_RS01315	COG1183	phosphatidylcholine synthase activity
MID02_RS01320	COG0586	Pfam SNARE associated Golgi protein
MID02_RS01325	COG0688	phosphatidylethanolamine metabolic process
MID02_RS01340	COG1301	dicarboxylic acid transport
MID02_RS01345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MID02_RS01350	COG0833	amino acid
MID02_RS01355	COG2040	homocysteine
MID02_RS01360	COG1115	amino acid carrier protein
MID02_RS01365	COG2066	Belongs to the glutaminase family
MID02_RS01370	COG4191	Histidine kinase
MID02_RS01375	COG0784	Response regulator, receiver
MID02_RS01380	COG3173	Aminoglycoside phosphotransferase
MID02_RS01390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MID02_RS01395	COG0778	Nitroreductase
MID02_RS01400	COG0346	lactoylglutathione lyase activity
MID02_RS01405	COG2259	Doxx family
MID02_RS01410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID02_RS01425	COG3773	Cell wall hydrolase
MID02_RS01430	COG3540	Alkaline phosphatase
MID02_RS01435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MID02_RS01440	COG0805	protein transport
MID02_RS01450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MID02_RS01455	COG0477	Major facilitator Superfamily
MID02_RS01460	COG1309	transcriptional regulator
MID02_RS01470	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MID02_RS01475	COG1405	negative regulation of cell septum assembly
MID02_RS01475	COG3012	SEC-C Motif Domain Protein
MID02_RS01480	COG0667	Aldo Keto reductase
MID02_RS01490	COG1595	DNA-templated transcription, initiation
MID02_RS01495	COG1595	DNA-templated transcription, initiation
MID02_RS01500	COG1876	peptidase activity
MID02_RS01505	COG0457	Tetratricopeptide repeat
MID02_RS01510	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS01515	COG0366	Alpha amylase catalytic
MID02_RS01520	COG0803	Belongs to the bacterial solute-binding protein 9 family
MID02_RS01525	COG1121	(ABC) transporter
MID02_RS01530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MID02_RS01535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MID02_RS01540	COG2310	stress, protein
MID02_RS01545	COG2310	stress, protein
MID02_RS01550	COG2310	stress, protein
MID02_RS01555	COG0861	Integral membrane protein TerC family
MID02_RS01565	COG3853	Toxic anion resistance protein (TelA)
MID02_RS01570	COG0477	Major facilitator Superfamily
MID02_RS01575	COG0517	IMP dehydrogenase activity
MID02_RS01575	COG4175	Glycine betaine
MID02_RS01580	COG4176	ABC-type proline glycine betaine transport system permease component
MID02_RS01585	COG2113	Glycine betaine
MID02_RS01590	COG1473	amidohydrolase
MID02_RS01595	COG1288	antiporter activity
MID02_RS01605	COG0366	Alpha amylase catalytic
MID02_RS01615	COG2814	Major facilitator Superfamily
MID02_RS01620	COG1846	Transcriptional regulator
MID02_RS01625	COG1280	lysine exporter protein (LysE YggA)
MID02_RS01630	COG3403	YqcI/YcgG family
MID02_RS01635	COG1113	amino acid transport
MID02_RS01640	COG3665	Urea carboxylase-associated protein
MID02_RS01655	COG1660	Displays ATPase and GTPase activities
MID02_RS01665	COG2271	Major facilitator Superfamily
MID02_RS01670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MID02_RS01675	COG3458	cephalosporin-C deacetylase activity
MID02_RS01680	COG3541	Predicted nucleotidyltransferase
MID02_RS01685	COG0506	proline dehydrogenase activity
MID02_RS01690	COG1012	belongs to the aldehyde dehydrogenase family
MID02_RS01695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MID02_RS01700	COG2508	Transcriptional regulator
MID02_RS01710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MID02_RS01710	COG1587	Uroporphyrinogen-III synthase
MID02_RS01715	COG2146	nitrite reductase [NAD(P)H] activity
MID02_RS01720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MID02_RS01730	COG0523	cobalamin synthesis protein
MID02_RS01735	COG1063	alcohol dehydrogenase
MID02_RS01740	COG1714	RDD family
MID02_RS01765	COG3209	COG3209 Rhs family protein
MID02_RS01770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MID02_RS01775	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MID02_RS01780	COG1733	regulation of RNA biosynthetic process
MID02_RS01785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS01815	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MID02_RS01830	COG2364	Membrane
MID02_RS01835	COG1126	abc transporter atp-binding protein
MID02_RS01840	COG0765	amino acid transport
MID02_RS01845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID02_RS01850	COG0583	DNA-binding transcription factor activity
MID02_RS01855	COG0163	prenyltransferase activity
MID02_RS01860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MID02_RS01875	COG3104	oligopeptide transport
MID02_RS01880	COG5434	Belongs to the glycosyl hydrolase 28 family
MID02_RS01890	COG0697	spore germination
MID02_RS01900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MID02_RS01905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MID02_RS01910	COG0456	acetyltransferase
MID02_RS01915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID02_RS01920	COG0765	amino acid transport
MID02_RS01925	COG1126	abc transporter atp-binding protein
MID02_RS01930	COG1473	amidohydrolase
MID02_RS01935	COG2079	MmgE PrpD family protein
MID02_RS01940	COG1136	(ABC) transporter
MID02_RS01945	COG0577	efflux transmembrane transporter activity
MID02_RS01950	COG0745	RESPONSE REGULATOR receiver
MID02_RS01955	COG5002	protein histidine kinase activity
MID02_RS01955	COG3850	Histidine kinase
MID02_RS01960	COG0457	Tetratricopeptide repeat
MID02_RS01975	COG0527	aspartate kinase activity
MID02_RS01980	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID02_RS01985	COG4605	iron ion homeostasis
MID02_RS01990	COG4604	ABC transporter, ATP-binding protein
MID02_RS01995	COG4607	ABC-type enterochelin transport system periplasmic component
MID02_RS02000	COG2814	Major facilitator Superfamily
MID02_RS02005	COG1309	transcriptional regulator
MID02_RS02010	COG0778	Nitroreductase
MID02_RS02015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MID02_RS02020	COG0640	Transcriptional regulator
MID02_RS02025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MID02_RS02030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MID02_RS02035	COG1012	belongs to the aldehyde dehydrogenase family
MID02_RS02040	COG4975	Glucose uptake
MID02_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS02050	COG4549	nuclear export factor GLE1
MID02_RS02055	COG1276	copper resistance
MID02_RS02055	COG2372	response to copper ion
MID02_RS02060	COG1349	DNA-binding transcription factor activity
MID02_RS02070	COG2213	PTS system mannitol-specific
MID02_RS02075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID02_RS02085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MID02_RS02095	COG0561	phosphatase activity
MID02_RS02105	COG1914	H( )-stimulated, divalent metal cation uptake system
MID02_RS02115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MID02_RS02120	COG1984	allophanate hydrolase subunit 2
MID02_RS02125	COG1414	Transcriptional regulator
MID02_RS02130	COG2755	lipolytic protein G-D-S-L family
MID02_RS02140	COG2329	Antibiotic biosynthesis monooxygenase
MID02_RS02145	COG0768	penicillin binding
MID02_RS02150	COG4989	oxidoreductase activity
MID02_RS02155	COG3711	transcriptional antiterminator
MID02_RS02160	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS02165	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS02170	COG1917	Cupin 2, conserved barrel domain protein
MID02_RS02175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MID02_RS02180	COG3871	stress protein (general stress protein 26)
MID02_RS02190	COG2814	Major facilitator Superfamily
MID02_RS02195	COG1522	sequence-specific DNA binding
MID02_RS02200	COG0551	DNA topoisomerase type I activity
MID02_RS02200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MID02_RS02205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MID02_RS02210	COG3706	GGDEF domain
MID02_RS02215	COG5298	Protein conserved in bacteria
MID02_RS02220	COG1215	transferase activity, transferring glycosyl groups
MID02_RS02230	COG0531	amino acid
MID02_RS02235	COG0494	nUDIX hydrolase
MID02_RS02240	COG0028	Belongs to the TPP enzyme family
MID02_RS02270	COG1914	H( )-stimulated, divalent metal cation uptake system
MID02_RS02290	COG2076	Multidrug Resistance protein
MID02_RS02295	COG2217	Heavy metal translocating P-type atpase
MID02_RS02300	COG3729	General stress protein
MID02_RS02305	COG0662	Cupin 2, conserved barrel domain protein
MID02_RS02310	COG2329	Antibiotic biosynthesis monooxygenase
MID02_RS02315	COG3546	catalase activity
MID02_RS02320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MID02_RS02325	COG3290	protein histidine kinase activity
MID02_RS02330	COG4565	transcriptional regulatory protein
MID02_RS02335	COG1301	dicarboxylic acid transport
MID02_RS02340	COG0628	permease
MID02_RS02345	COG1131	(ABC) transporter
MID02_RS02350	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MID02_RS02360	COG1960	acyl-CoA dehydrogenase activity
MID02_RS02375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MID02_RS02380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID02_RS02390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MID02_RS02395	COG0513	Belongs to the DEAD box helicase family
MID02_RS02400	COG3402	PFAM membrane-flanked domain
MID02_RS02405	COG3428	Bacterial PH domain
MID02_RS02410	COG0705	Rhomboid family
MID02_RS02420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MID02_RS02425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MID02_RS02430	COG0864	Transcriptional regulator
MID02_RS02435	COG2337	Toxic component of a toxin-antitoxin (TA) module
MID02_RS02440	COG1366	Belongs to the anti-sigma-factor antagonist family
MID02_RS02445	COG1366	Belongs to the anti-sigma-factor antagonist family
MID02_RS02450	COG2172	sigma factor antagonist activity
MID02_RS02455	COG2208	phosphoserine phosphatase activity
MID02_RS02460	COG1366	Belongs to the anti-sigma-factor antagonist family
MID02_RS02470	COG1191	sigma factor activity
MID02_RS02475	COG2208	phosphoserine phosphatase activity
MID02_RS02480	COG2183	response to ionizing radiation
MID02_RS02530	COG2249	NAD(P)H dehydrogenase (quinone) activity
MID02_RS02550	COG0477	Major facilitator Superfamily
MID02_RS02560	COG1764	response to oxidative stress
MID02_RS02565	COG1846	Transcriptional regulator
MID02_RS02575	COG1959	2 iron, 2 sulfur cluster binding
MID02_RS02580	COG2910	NAD(P)H-binding
MID02_RS02585	COG1278	Cold shock
MID02_RS02595	COG1937	Protein conserved in bacteria
MID02_RS02600	COG2210	Belongs to the sulfur carrier protein TusA family
MID02_RS02610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MID02_RS02610	COG0425	Belongs to the sulfur carrier protein TusA family
MID02_RS02620	COG0425	Belongs to the sulfur carrier protein TusA family
MID02_RS02625	COG0730	response to heat
MID02_RS02630	COG1794	racemase activity, acting on amino acids and derivatives
MID02_RS02645	COG3621	Patatin-like phospholipase
MID02_RS02655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MID02_RS02660	COG1802	Transcriptional regulator
MID02_RS02665	COG0251	oxidation-reduction process
MID02_RS02670	COG0814	amino acid
MID02_RS02675	COG1473	amidohydrolase
MID02_RS02680	COG2207	Transcriptional regulator
MID02_RS02680	COG1917	Cupin 2, conserved barrel domain protein
MID02_RS02690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MID02_RS02695	COG0477	Major facilitator Superfamily
MID02_RS02715	COG0277	FAD linked oxidase domain protein
MID02_RS02750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MID02_RS02775	COG1064	alcohol dehydrogenase
MID02_RS02780	COG0789	Transcriptional regulator
MID02_RS02790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MID02_RS02805	COG2814	Major facilitator Superfamily
MID02_RS02810	COG1309	transcriptional regulator
MID02_RS02815	COG5577	PFAM Coat F domain
MID02_RS02825	COG1063	alcohol dehydrogenase
MID02_RS02830	COG5577	PFAM Coat F domain
MID02_RS02840	COG4585	Histidine kinase
MID02_RS02845	COG2197	response regulator
MID02_RS02850	COG2409	Drug exporters of the RND superfamily
MID02_RS02855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MID02_RS02860	COG0488	(ABC) transporter
MID02_RS02865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MID02_RS02870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MID02_RS02880	COG2814	Major facilitator Superfamily
MID02_RS02885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MID02_RS02895	COG0730	response to heat
MID02_RS02900	COG0456	acetyltransferase
MID02_RS02905	COG4978	Transcriptional regulator
MID02_RS02905	COG0789	Transcriptional regulator
MID02_RS02910	COG0697	spore germination
MID02_RS02915	COG1051	belongs to the nudix hydrolase family
MID02_RS02920	COG2226	methyltransferase
MID02_RS02940	COG1802	Transcriptional regulator
MID02_RS02945	COG1819	glycosyl
MID02_RS02960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MID02_RS02970	COG1388	LysM domain
MID02_RS02975	COG2814	Major facilitator Superfamily
MID02_RS02980	COG2188	Transcriptional regulator
MID02_RS02985	COG2186	Transcriptional regulator
MID02_RS02990	COG2807	transmembrane transport
MID02_RS02995	COG2076	Multidrug Resistance protein
MID02_RS03000	COG2076	Multidrug Resistance protein
MID02_RS03005	COG1309	transcriptional regulator
MID02_RS03010	COG0531	amino acid
MID02_RS03020	COG3832	glyoxalase III activity
MID02_RS03025	COG0604	alcohol dehydrogenase
MID02_RS03030	COG2814	Major facilitator Superfamily
MID02_RS03070	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MID02_RS03075	COG0802	atpase or kinase
MID02_RS03080	COG1214	PFAM Peptidase M22, glycoprotease
MID02_RS03085	COG0456	acetyltransferase
MID02_RS03090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MID02_RS03095	COG0488	(ABC) transporter
MID02_RS03110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MID02_RS03115	COG0805	protein transport
MID02_RS03125	COG1266	CAAX protease self-immunity
MID02_RS03145	COG0457	Tetratricopeptide repeat
MID02_RS03150	COG1063	alcohol dehydrogenase
MID02_RS03155	COG2211	Major facilitator Superfamily
MID02_RS03160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MID02_RS03170	COG1842	Phage shock protein A
MID02_RS03175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MID02_RS03180	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MID02_RS03185	COG4260	virion core protein, lumpy skin disease virus
MID02_RS03190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MID02_RS03190	COG2755	lipolytic protein G-D-S-L family
MID02_RS03200	COG1595	DNA-templated transcription, initiation
MID02_RS03205	COG1063	alcohol dehydrogenase
MID02_RS03210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MID02_RS03215	COG0823	Involved in the tonB-independent uptake of proteins
MID02_RS03230	COG2132	Multicopper oxidase
MID02_RS03235	COG1113	amino acid transport
MID02_RS03240	COG0714	Associated with various cellular activities
MID02_RS03245	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MID02_RS03250	COG1305	Transglutaminase-like
MID02_RS03270	COG2252	PERMEase
MID02_RS03275	COG3064	Membrane
MID02_RS03295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MID02_RS03300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MID02_RS03305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MID02_RS03310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MID02_RS03315	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MID02_RS03330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MID02_RS03340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MID02_RS03345	COG0138	bifunctional purine biosynthesis protein purh
MID02_RS03350	COG0151	Belongs to the GarS family
MID02_RS03360	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MID02_RS03365	COG1470	cell adhesion involved in biofilm formation
MID02_RS03370	COG4496	protein, YerC YecD
MID02_RS03375	COG0069	glutamate synthase activity
MID02_RS03385	COG0210	DNA helicase
MID02_RS03395	COG4851	CamS sex pheromone cAM373 precursor
MID02_RS03400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MID02_RS03405	COG1285	pathogenesis
MID02_RS03410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MID02_RS03430	COG1309	transcriptional regulator
MID02_RS03435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID02_RS03440	COG1597	lipid kinase activity
MID02_RS03445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MID02_RS03450	COG0745	RESPONSE REGULATOR receiver
MID02_RS03465	COG5002	protein histidine kinase activity
MID02_RS03470	COG1024	Enoyl-CoA hydratase
MID02_RS03475	COG1024	Enoyl-CoA hydratase
MID02_RS03480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS03490	COG0604	alcohol dehydrogenase
MID02_RS03490	COG3321	synthase
MID02_RS03495	COG1131	(ABC) transporter
MID02_RS03510	COG4221	oxidoreductase activity
MID02_RS03510	COG3321	synthase
MID02_RS03510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS03510	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS03515	COG4221	oxidoreductase activity
MID02_RS03515	COG3321	synthase
MID02_RS03515	COG0300	oxidoreductase activity
MID02_RS03515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS03520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS03520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS03520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS03520	COG3321	synthase
MID02_RS03520	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS03525	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS03525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS03525	COG4221	oxidoreductase activity
MID02_RS03525	COG3321	synthase
MID02_RS03530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS03530	COG0300	oxidoreductase activity
MID02_RS03530	COG3321	synthase
MID02_RS03530	COG4221	oxidoreductase activity
MID02_RS03540	COG3425	synthase
MID02_RS03575	COG3546	catalase activity
MID02_RS03580	COG0454	-acetyltransferase
MID02_RS03590	COG2323	membrane
MID02_RS03595	COG2329	Antibiotic biosynthesis monooxygenase
MID02_RS03600	COG0346	lactoylglutathione lyase activity
MID02_RS03605	COG1366	Belongs to the anti-sigma-factor antagonist family
MID02_RS03610	COG5583	Uncharacterized small protein (DUF2292)
MID02_RS03615	COG0196	riboflavin kinase activity
MID02_RS03620	COG0670	Belongs to the BI1 family
MID02_RS03630	COG1846	Transcriptional regulator
MID02_RS03635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MID02_RS03645	COG2124	cytochrome p450
MID02_RS03645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MID02_RS03650	COG1368	sulfuric ester hydrolase activity
MID02_RS03655	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MID02_RS03660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS03665	COG1442	glycosyl transferase family 8
MID02_RS03670	COG1216	Glycosyl transferase, family 2
MID02_RS03675	COG1442	glycosyl transferase family 8
MID02_RS03680	COG2223	nitrite transmembrane transporter activity
MID02_RS03685	COG0531	amino acid
MID02_RS03690	COG1012	belongs to the aldehyde dehydrogenase family
MID02_RS03695	COG0840	transmembrane signaling receptor activity
MID02_RS03700	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS03705	COG0457	Tetratricopeptide repeat
MID02_RS03705	COG0463	Glycosyl transferase, family 2
MID02_RS03710	COG0488	(ABC) transporter
MID02_RS03715	COG0789	Transcriptional regulator
MID02_RS03720	COG2814	Major facilitator Superfamily
MID02_RS03725	COG0488	(ABC) transporter
MID02_RS03730	COG0513	Belongs to the DEAD box helicase family
MID02_RS03740	COG2130	NADP-dependent
MID02_RS03755	COG3866	Pectate lyase
MID02_RS03760	COG0471	metal ion transport
MID02_RS03790	COG0745	RESPONSE REGULATOR receiver
MID02_RS03790	COG2972	Histidine kinase
MID02_RS03800	COG3279	Response regulator of the LytR AlgR family
MID02_RS03810	COG3764	Sortase (surface protein transpeptidase)
MID02_RS03815	COG3290	protein histidine kinase activity
MID02_RS03820	COG4565	transcriptional regulatory protein
MID02_RS03825	COG3181	Tripartite tricarboxylate transporter family receptor
MID02_RS03830	COG2851	Citrate transporter
MID02_RS03835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MID02_RS03840	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MID02_RS03850	COG2258	MOSC domain
MID02_RS03870	COG0024	Methionine aminopeptidase
MID02_RS03875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID02_RS03875	COG1263	PTS System
MID02_RS03885	COG1368	sulfuric ester hydrolase activity
MID02_RS03895	COG0071	Belongs to the small heat shock protein (HSP20) family
MID02_RS03910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID02_RS03910	COG1263	PTS System
MID02_RS03915	COG0366	Alpha amylase catalytic
MID02_RS03920	COG2188	Transcriptional regulator
MID02_RS03925	COG0778	Nitroreductase
MID02_RS03940	COG0737	Belongs to the 5'-nucleotidase family
MID02_RS03945	COG0693	protein deglycase activity
MID02_RS03950	COG1609	Transcriptional regulator
MID02_RS03965	COG2814	Major facilitator Superfamily
MID02_RS03975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MID02_RS03980	COG4980	gas vesicle protein
MID02_RS03985	COG1295	ribonuclease BN
MID02_RS03990	COG0477	Major facilitator Superfamily
MID02_RS03995	COG0387	Pfam Sodium calcium exchanger
MID02_RS04005	COG0668	transmembrane transport
MID02_RS04010	COG0535	radical SAM domain protein
MID02_RS04020	COG0726	polysaccharide deacetylase
MID02_RS04025	COG2084	Dehydrogenase
MID02_RS04035	COG0598	Magnesium transport protein CorA
MID02_RS04040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MID02_RS04045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MID02_RS04055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MID02_RS04060	COG4637	Psort location Cytoplasmic, score
MID02_RS04065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MID02_RS04070	COG0022	dehydrogenase e1 component
MID02_RS04075	COG0508	dehydrogenase complex catalyzes the overall conversion of
MID02_RS04080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MID02_RS04085	COG3284	Transcriptional regulator
MID02_RS04095	COG1486	melibiose metabolic process
MID02_RS04100	COG1737	Transcriptional regulator
MID02_RS04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID02_RS04105	COG1263	PTS System
MID02_RS04110	COG1132	(ABC) transporter
MID02_RS04115	COG1132	(ABC) transporter
MID02_RS04120	COG2259	Doxx family
MID02_RS04125	COG2514	catechol 2,3-dioxygenase activity
MID02_RS04135	COG1695	Transcriptional regulator
MID02_RS04140	COG2249	NAD(P)H dehydrogenase (quinone) activity
MID02_RS04145	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MID02_RS04150	COG0574	Belongs to the PEP-utilizing enzyme family
MID02_RS04150	COG3848	Pyruvate phosphate dikinase
MID02_RS04155	COG2732	(Barnase) inhibitor
MID02_RS04160	COG2318	DinB family
MID02_RS04165	COG2814	Major facilitator Superfamily
MID02_RS04170	COG1846	Transcriptional regulator
MID02_RS04175	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MID02_RS04175	COG0392	lysyltransferase activity
MID02_RS04180	COG0384	phenazine biosynthesis protein PhzF
MID02_RS04185	COG0778	Nitroreductase
MID02_RS04200	COG1090	epimerase
MID02_RS04215	COG2814	Major facilitator Superfamily
MID02_RS04225	COG3591	Belongs to the peptidase S1B family
MID02_RS04240	COG3103	Sh3 type 3 domain protein
MID02_RS04245	COG5658	integral membrane protein
MID02_RS04250	COG0596	Alpha beta hydrolase
MID02_RS04255	COG0463	Glycosyl transferase, family 2
MID02_RS04260	COG4485	Bacterial membrane protein, YfhO
MID02_RS04265	COG1988	membrane-bound metal-dependent
MID02_RS04270	COG1194	a g-specific adenine glycosylase
MID02_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS04300	COG1132	(ABC) transporter
MID02_RS04305	COG4129	membrane
MID02_RS04315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MID02_RS04320	COG0735	belongs to the Fur family
MID02_RS04435	COG3340	Belongs to the peptidase S51 family
MID02_RS04445	COG0277	FAD linked oxidase domain protein
MID02_RS04455	COG0747	negative chemotaxis
MID02_RS04460	COG0601	transmembrane transport
MID02_RS04465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MID02_RS04470	COG0444	Belongs to the ABC transporter superfamily
MID02_RS04475	COG4608	Belongs to the ABC transporter superfamily
MID02_RS04480	COG0753	catalase activity
MID02_RS04490	COG1116	anion transmembrane transporter activity
MID02_RS04495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MID02_RS04500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MID02_RS04520	COG1476	TRANSCRIPTIONal
MID02_RS04530	COG3382	B3 4 domain protein
MID02_RS04535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MID02_RS04545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MID02_RS04550	COG0789	Transcriptional regulator
MID02_RS04555	COG1664	Polymer-forming cytoskeletal
MID02_RS04560	COG1664	Polymer-forming cytoskeletal
MID02_RS04565	COG2766	serine protein kinase
MID02_RS04575	COG1846	Transcriptional regulator
MID02_RS04580	COG1566	PFAM secretion protein HlyD family protein
MID02_RS04585	COG2814	Major facilitator Superfamily
MID02_RS04590	COG0655	NAD(P)H dehydrogenase (quinone) activity
MID02_RS04605	COG1725	Transcriptional regulator
MID02_RS04610	COG1131	(ABC) transporter
MID02_RS04615	COG1131	(ABC) transporter
MID02_RS04620	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MID02_RS04625	COG1278	Cold shock
MID02_RS04630	COG1464	Belongs to the NlpA lipoprotein family
MID02_RS04635	COG3706	GGDEF domain
MID02_RS04640	COG1823	symporter activity
MID02_RS04660	COG5577	PFAM Coat F domain
MID02_RS04665	COG0737	Belongs to the 5'-nucleotidase family
MID02_RS04665	COG1525	nuclease
MID02_RS04665	COG4085	toxin activity
MID02_RS04670	COG3764	Sortase (surface protein transpeptidase)
MID02_RS04675	COG0564	pseudouridine synthase activity
MID02_RS04685	COG0517	IMP dehydrogenase activity
MID02_RS04690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MID02_RS04695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MID02_RS04695	COG3153	acetyltransferase
MID02_RS04700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MID02_RS04705	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MID02_RS04710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MID02_RS04720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MID02_RS04725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MID02_RS04740	COG0431	NADPH-dependent FMN reductase
MID02_RS04755	COG0791	NLP P60 protein
MID02_RS04755	COG1388	LysM domain
MID02_RS04760	COG1959	2 iron, 2 sulfur cluster binding
MID02_RS04770	COG2719	SpoVR family
MID02_RS04775	COG1785	Belongs to the alkaline phosphatase family
MID02_RS04780	COG0791	NLP P60 protein
MID02_RS04780	COG1388	LysM domain
MID02_RS04785	COG0583	DNA-binding transcription factor activity
MID02_RS04790	COG0372	Belongs to the citrate synthase family
MID02_RS04795	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS04800	COG0531	amino acid
MID02_RS04805	COG0733	neurotransmitter:sodium symporter activity
MID02_RS04820	COG1595	DNA-templated transcription, initiation
MID02_RS04825	COG0204	Acyl-transferase
MID02_RS04830	COG1253	flavin adenine dinucleotide binding
MID02_RS04835	COG0789	Transcriptional regulator
MID02_RS04840	COG0436	Aminotransferase
MID02_RS04845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MID02_RS04850	COG1253	flavin adenine dinucleotide binding
MID02_RS04855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MID02_RS04860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MID02_RS04865	COG0584	glycerophosphoryl diester phosphodiesterase
MID02_RS04875	COG0668	transmembrane transport
MID02_RS04880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MID02_RS04885	COG0726	polysaccharide deacetylase
MID02_RS04890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MID02_RS04895	COG3226	Transcriptional regulator
MID02_RS04905	COG0589	response to stress
MID02_RS04910	COG1132	(ABC) transporter
MID02_RS04915	COG1132	(ABC) transporter
MID02_RS04920	COG0702	epimerase
MID02_RS04940	COG0189	ligase activity
MID02_RS04945	COG0189	ligase activity
MID02_RS04960	COG4335	DNA alkylation repair
MID02_RS04965	COG0561	phosphatase activity
MID02_RS04970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MID02_RS04980	COG0475	glutathione-regulated potassium exporter activity
MID02_RS04985	COG0490	domain, Protein
MID02_RS04995	COG1024	Enoyl-CoA hydratase
MID02_RS05005	COG4152	abc transporter atp-binding protein
MID02_RS05010	COG1668	transmembrane transport
MID02_RS05015	COG0420	3'-5' exonuclease activity
MID02_RS05020	COG4717	serine-type aminopeptidase activity
MID02_RS05035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MID02_RS05070	COG4980	gas vesicle protein
MID02_RS05085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MID02_RS05090	COG0537	adenosine 5'-monophosphoramidase activity
MID02_RS05095	COG1131	(ABC) transporter
MID02_RS05100	COG4473	ABC transporter
MID02_RS05110	COG1473	amidohydrolase
MID02_RS05115	COG3069	C4-dicarboxylate transmembrane transporter activity
MID02_RS05120	COG2329	Antibiotic biosynthesis monooxygenase
MID02_RS05125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MID02_RS05135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MID02_RS05140	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MID02_RS05145	COG1309	transcriptional regulator
MID02_RS05150	COG1511	domain protein
MID02_RS05155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MID02_RS05165	COG1363	Peptidase, m42
MID02_RS05170	COG1301	dicarboxylic acid transport
MID02_RS05180	COG1234	tRNA 3'-trailer cleavage
MID02_RS05185	COG0095	Lipoate-protein ligase
MID02_RS05190	COG0702	epimerase
MID02_RS05195	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS05205	COG0501	Belongs to the peptidase M48B family
MID02_RS05210	COG1404	Belongs to the peptidase S8 family
MID02_RS05215	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MID02_RS05220	COG0406	alpha-ribazole phosphatase activity
MID02_RS05225	COG0183	Belongs to the thiolase family
MID02_RS05230	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS05235	COG1268	BioY protein
MID02_RS05240	COG0840	transmembrane signaling receptor activity
MID02_RS05245	COG0723	plastoquinol--plastocyanin reductase activity
MID02_RS05245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MID02_RS05250	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS05260	COG4903	ComK protein
MID02_RS05270	COG5646	InterPro IPR014922
MID02_RS05290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MID02_RS05305	COG0398	Pfam SNARE associated Golgi protein
MID02_RS05310	COG0681	Belongs to the peptidase S26 family
MID02_RS05315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MID02_RS05320	COG1846	Transcriptional regulator
MID02_RS05325	COG3180	Ammonia monooxygenase
MID02_RS05330	COG2814	Major facilitator Superfamily
MID02_RS05340	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MID02_RS05345	COG2323	membrane
MID02_RS05360	COG0420	3'-5' exonuclease activity
MID02_RS05365	COG0419	ATPase involved in DNA repair
MID02_RS05370	COG1403	HNH endonuclease
MID02_RS05410	COG0179	Fumarylacetoacetate (FAA) hydrolase
MID02_RS05430	COG0367	asparagine synthase
MID02_RS05435	COG1562	ergosterol biosynthetic process
MID02_RS05440	COG0534	Mate efflux family protein
MID02_RS05445	COG1917	Cupin 2, conserved barrel domain protein
MID02_RS05445	COG2207	Transcriptional regulator
MID02_RS05450	COG1609	Transcriptional regulator
MID02_RS05455	COG0673	inositol 2-dehydrogenase activity
MID02_RS05460	COG2318	DinB family
MID02_RS05465	COG1357	PFAM Pentapeptide repeats (8 copies)
MID02_RS05470	COG2153	protein acetylation
MID02_RS05475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MID02_RS05475	COG0646	methionine synthase
MID02_RS05485	COG2996	Protein conserved in bacteria
MID02_RS05490	COG1744	ABC transporter substrate-binding protein PnrA-like
MID02_RS05495	COG0840	transmembrane signaling receptor activity
MID02_RS05505	COG1307	EDD domain protein, DegV family
MID02_RS05510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MID02_RS05530	COG0561	phosphatase activity
MID02_RS05535	COG1073	alpha beta
MID02_RS05540	COG2151	metal-sulfur cluster biosynthetic enzyme
MID02_RS05550	COG0277	FAD linked oxidase domain protein
MID02_RS05555	COG2271	Major facilitator Superfamily
MID02_RS05565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MID02_RS05575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MID02_RS05580	COG0505	Belongs to the CarA family
MID02_RS05585	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MID02_RS05590	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MID02_RS05605	COG2267	carboxylic ester hydrolase activity
MID02_RS05615	COG1744	ABC transporter substrate-binding protein PnrA-like
MID02_RS05630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MID02_RS05635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MID02_RS05640	COG5504	Zn-dependent protease
MID02_RS05645	COG0444	Belongs to the ABC transporter superfamily
MID02_RS05650	COG4608	Belongs to the ABC transporter superfamily
MID02_RS05660	COG0601	transmembrane transport
MID02_RS05665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MID02_RS05675	COG0180	Tryptophanyl-tRNA synthetase
MID02_RS05680	COG4166	transmembrane transport
MID02_RS05685	COG0601	transmembrane transport
MID02_RS05690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MID02_RS05695	COG0444	Belongs to the ABC transporter superfamily
MID02_RS05700	COG4608	Belongs to the ABC transporter superfamily
MID02_RS05710	COG0456	acetyltransferase
MID02_RS05715	COG1393	Belongs to the ArsC family
MID02_RS05720	COG0861	Integral membrane protein TerC family
MID02_RS05730	COG4862	establishment of competence for transformation
MID02_RS05735	COG4469	Competence protein
MID02_RS05740	COG1164	Oligoendopeptidase f
MID02_RS05750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MID02_RS05755	COG2346	COG2346, Truncated hemoglobins
MID02_RS05760	COG0741	lytic transglycosylase activity
MID02_RS05765	COG4116	CYTH
MID02_RS05775	COG2357	RelA SpoT domain protein
MID02_RS05780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MID02_RS05785	COG0564	pseudouridine synthase activity
MID02_RS05795	COG0475	glutathione-regulated potassium exporter activity
MID02_RS05795	COG0569	domain protein
MID02_RS05800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MID02_RS05805	COG0352	thiamine-phosphate diphosphorylase activity
MID02_RS05810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MID02_RS05815	COG2104	thiamine diphosphate biosynthetic process
MID02_RS05825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MID02_RS05830	COG0351	phosphomethylpyrimidine kinase
MID02_RS05835	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MID02_RS05890	COG0210	DNA helicase
MID02_RS05910	COG2153	protein acetylation
MID02_RS05920	COG2382	esterase
MID02_RS05925	COG0626	cystathionine gamma-synthase activity
MID02_RS05930	COG0626	cystathionine gamma-synthase activity
MID02_RS05940	COG0582	viral genome integration into host DNA
MID02_RS05945	COG2856	Zn peptidase
MID02_RS05955	COG1396	sequence-specific DNA binding
MID02_RS06005	COG3935	DnaD domain protein
MID02_RS06010	COG1484	DNA-dependent DNA replication
MID02_RS06020	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MID02_RS06050	COG1404	Belongs to the peptidase S8 family
MID02_RS06060	COG1595	DNA-templated transcription, initiation
MID02_RS06080	COG5484	DNA packaging
MID02_RS06085	COG1783	phage Terminase large subunit
MID02_RS06195	COG4824	toxin secretion phage lysis holin
MID02_RS06200	COG1388	LysM domain
MID02_RS06200	COG3409	Peptidoglycan-binding domain 1 protein
MID02_RS06200	COG5632	N-Acetylmuramoyl-L-alanine amidase
MID02_RS06210	COG5444	nuclease activity
MID02_RS06230	COG0582	viral genome integration into host DNA
MID02_RS06235	COG2856	Zn peptidase
MID02_RS06245	COG1396	sequence-specific DNA binding
MID02_RS06295	COG3935	DnaD domain protein
MID02_RS06300	COG1484	DNA-dependent DNA replication
MID02_RS06310	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MID02_RS06340	COG1404	Belongs to the peptidase S8 family
MID02_RS06350	COG1595	DNA-templated transcription, initiation
MID02_RS06370	COG5484	DNA packaging
MID02_RS06375	COG1783	phage Terminase large subunit
MID02_RS06485	COG4824	toxin secretion phage lysis holin
MID02_RS06490	COG5632	N-Acetylmuramoyl-L-alanine amidase
MID02_RS06490	COG1388	LysM domain
MID02_RS06490	COG3409	Peptidoglycan-binding domain 1 protein
MID02_RS06500	COG5444	nuclease activity
MID02_RS06525	COG5444	nuclease activity
MID02_RS06535	COG0346	lactoylglutathione lyase activity
MID02_RS06540	COG2367	Beta-lactamase
MID02_RS06545	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MID02_RS06555	COG1846	Transcriptional regulator
MID02_RS06565	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MID02_RS06570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MID02_RS06575	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MID02_RS06580	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MID02_RS06580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MID02_RS06585	COG1447	Phosphotransferase system cellobiose-specific component IIA
MID02_RS06595	COG1349	DNA-binding transcription factor activity
MID02_RS06610	COG1285	pathogenesis
MID02_RS06625	COG2205	protein histidine kinase activity
MID02_RS06635	COG3383	formate dehydrogenase (NAD+) activity
MID02_RS06640	COG2427	Protein of unknown function (DUF1641)
MID02_RS06645	COG2124	cytochrome p450
MID02_RS06650	COG1819	glycosyl
MID02_RS06660	COG1587	Uroporphyrinogen-III synthase
MID02_RS06665	COG0390	transport system, permease component
MID02_RS06670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MID02_RS06675	COG0697	spore germination
MID02_RS06680	COG4297	protein containing double-stranded beta helix domain
MID02_RS06690	COG1252	NADH dehydrogenase
MID02_RS06700	COG2211	Major facilitator Superfamily
MID02_RS06705	COG1609	Transcriptional regulator
MID02_RS06710	COG0246	Mannitol dehydrogenase
MID02_RS06715	COG2721	sulfolactate sulfo-lyase activity
MID02_RS06720	COG0730	response to heat
MID02_RS06725	COG2318	DinB family
MID02_RS06730	COG0457	Tetratricopeptide repeat
MID02_RS06740	COG1388	LysM domain
MID02_RS06740	COG3409	Peptidoglycan-binding domain 1 protein
MID02_RS06740	COG5632	N-Acetylmuramoyl-L-alanine amidase
MID02_RS06750	COG4195	phage-related replication protein
MID02_RS06755	COG2856	Zn peptidase
MID02_RS06760	COG1396	sequence-specific DNA binding
MID02_RS06770	COG1522	sequence-specific DNA binding
MID02_RS06775	COG1484	DNA-dependent DNA replication
MID02_RS06795	COG1595	DNA-templated transcription, initiation
MID02_RS06800	COG5484	DNA packaging
MID02_RS06800	COG3728	DNA packaging
MID02_RS06805	COG1783	phage Terminase large subunit
MID02_RS06810	COG5518	Phage portal protein
MID02_RS06815	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MID02_RS06820	COG4653	Phage capsid family
MID02_RS06870	COG3953	SLT domain
MID02_RS06870	COG5412	phage tail tape measure protein
MID02_RS06870	COG3953	SLT domain
MID02_RS06870	COG5412	phage tail tape measure protein
MID02_RS06870	COG3953	SLT domain
MID02_RS06870	COG5412	phage tail tape measure protein
MID02_RS06875	COG1652	LysM domain
MID02_RS06880	COG4193	domain, Protein
MID02_RS06890	COG3628	GPW Gp25 family protein
MID02_RS06895	COG3299	homolog of phage Mu protein gp47
MID02_RS06900	COG3778	Protein conserved in bacteria
MID02_RS06940	COG3409	Peptidoglycan-binding domain 1 protein
MID02_RS06940	COG5632	N-Acetylmuramoyl-L-alanine amidase
MID02_RS06960	COG0306	phosphate transporter
MID02_RS06965	COG1392	Phosphate transport regulator
MID02_RS06970	COG0531	amino acid
MID02_RS06975	COG0346	lactoylglutathione lyase activity
MID02_RS06980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MID02_RS06985	COG0463	Glycosyl transferase, family 2
MID02_RS06995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MID02_RS07000	COG0477	Major facilitator Superfamily
MID02_RS07005	COG2362	D-Aminopeptidase
MID02_RS07010	COG0601	transmembrane transport
MID02_RS07015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MID02_RS07020	COG0444	Belongs to the ABC transporter superfamily
MID02_RS07025	COG4166	transmembrane transport
MID02_RS07030	COG1619	proteins homologs of microcin C7 resistance protein MccF
MID02_RS07035	COG4948	Mandelate Racemase Muconate Lactonizing
MID02_RS07040	COG0791	NLP P60 protein
MID02_RS07045	COG4608	Belongs to the ABC transporter superfamily
MID02_RS07050	COG2706	6-phosphogluconolactonase activity
MID02_RS07055	COG1834	amidinotransferase
MID02_RS07060	COG1607	acyl-coa hydrolase
MID02_RS07065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MID02_RS07070	COG2076	Multidrug Resistance protein
MID02_RS07075	COG2076	Multidrug Resistance protein
MID02_RS07080	COG0788	formyltetrahydrofolate deformylase activity
MID02_RS07085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MID02_RS07095	COG1764	response to oxidative stress
MID02_RS07100	COG1846	Transcriptional regulator
MID02_RS07105	COG1764	response to oxidative stress
MID02_RS07120	COG0457	Tetratricopeptide repeat
MID02_RS07120	COG0463	Glycosyl transferase, family 2
MID02_RS07130	COG2814	Major facilitator Superfamily
MID02_RS07135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MID02_RS07145	COG1404	Belongs to the peptidase S8 family
MID02_RS07150	COG1366	Belongs to the anti-sigma-factor antagonist family
MID02_RS07155	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MID02_RS07160	COG1122	ATPase activity
MID02_RS07165	COG4721	ABC-type cobalt transport system, permease component
MID02_RS07170	COG1388	LysM domain
MID02_RS07170	COG3858	chitin binding
MID02_RS07180	COG2239	Acts as a magnesium transporter
MID02_RS07185	COG0789	Transcriptional regulator
MID02_RS07200	COG1846	Transcriptional regulator
MID02_RS07205	COG0726	polysaccharide deacetylase
MID02_RS07210	COG3285	dna ligase
MID02_RS07210	COG1793	dna ligase
MID02_RS07215	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MID02_RS07220	COG0586	Pfam SNARE associated Golgi protein
MID02_RS07230	COG1191	sigma factor activity
MID02_RS07255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MID02_RS07260	COG2323	membrane
MID02_RS07270	COG3594	Acyltransferase
MID02_RS07275	COG5002	protein histidine kinase activity
MID02_RS07280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MID02_RS07300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MID02_RS07305	COG0436	Aminotransferase
MID02_RS07335	COG3852	Histidine kinase
MID02_RS07340	COG1846	Transcriptional regulator
MID02_RS07345	COG1360	Flagellar Motor Protein
MID02_RS07350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MID02_RS07355	COG0542	response to heat
MID02_RS07360	COG3949	Membrane
MID02_RS07375	COG0720	synthase
MID02_RS07380	COG0602	queuosine metabolic process
MID02_RS07395	COG4873	Protein conserved in bacteria
MID02_RS07405	COG3773	Cell wall hydrolase
MID02_RS07410	COG2244	polysaccharide biosynthetic process
MID02_RS07415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID02_RS07420	COG2217	Heavy metal translocating P-type atpase
MID02_RS07425	COG0006	proline dipeptidase activity
MID02_RS07430	COG1609	Transcriptional regulator
MID02_RS07435	COG3711	transcriptional antiterminator
MID02_RS07440	COG1263	PTS System
MID02_RS07440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID02_RS07440	COG2190	(PTS) system
MID02_RS07445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID02_RS07450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MID02_RS07460	COG1533	DNA photolyase activity
MID02_RS07465	COG0840	transmembrane signaling receptor activity
MID02_RS07470	COG2084	Dehydrogenase
MID02_RS07475	COG2340	Cysteine-rich secretory protein family
MID02_RS07480	COG0768	penicillin binding
MID02_RS07485	COG4191	Histidine kinase
MID02_RS07490	COG0436	Aminotransferase
MID02_RS07500	COG0784	Response regulator, receiver
MID02_RS07500	COG0835	chemotaxis
MID02_RS07510	COG2814	Major facilitator Superfamily
MID02_RS07515	COG1376	ErfK ybiS ycfS ynhG family protein
MID02_RS07520	COG1408	metallophosphoesterase
MID02_RS07525	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS07535	COG2200	EAL domain
MID02_RS07540	COG4703	Protein of unknown function (DUF1797)
MID02_RS07545	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MID02_RS07555	COG0517	IMP dehydrogenase activity
MID02_RS07560	COG0583	DNA-binding transcription factor activity
MID02_RS07565	COG0716	FMN binding
MID02_RS07575	COG0716	FMN binding
MID02_RS07595	COG0668	transmembrane transport
MID02_RS07600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID02_RS07620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MID02_RS07625	COG0303	'Molybdopterin
MID02_RS07630	COG1763	Mo-molybdopterin cofactor biosynthetic process
MID02_RS07635	COG0314	molybdopterin synthase activity
MID02_RS07640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MID02_RS07650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MID02_RS07655	COG1136	(ABC) transporter
MID02_RS07660	COG0577	efflux transmembrane transporter activity
MID02_RS07665	COG1349	DNA-binding transcription factor activity
MID02_RS07670	COG1105	Belongs to the carbohydrate kinase PfkB family
MID02_RS07675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID02_RS07675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID02_RS07675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID02_RS07680	COG0681	Belongs to the peptidase S26 family
MID02_RS07690	COG0488	(ABC) transporter
MID02_RS07695	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MID02_RS07700	COG2309	aminopeptidase activity
MID02_RS07710	COG1077	Cell shape determining protein MreB Mrl
MID02_RS07715	COG2002	toxin-antitoxin pair type II binding
MID02_RS07720	COG3852	Histidine kinase
MID02_RS07725	COG2105	PFAM AIG2 family protein
MID02_RS07725	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MID02_RS07730	COG0569	domain protein
MID02_RS07740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MID02_RS07750	COG0561	phosphatase activity
MID02_RS07755	COG0242	peptide deformylase activity
MID02_RS07765	COG0497	DNA recombination
MID02_RS07775	COG4221	oxidoreductase activity
MID02_RS07775	COG3321	synthase
MID02_RS07775	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS07775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS07780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS07780	COG3321	synthase
MID02_RS07780	COG4221	oxidoreductase activity
MID02_RS07780	COG0300	oxidoreductase activity
MID02_RS07785	COG4221	oxidoreductase activity
MID02_RS07785	COG3321	synthase
MID02_RS07785	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS07785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS07790	COG0300	oxidoreductase activity
MID02_RS07790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS07790	COG4221	oxidoreductase activity
MID02_RS07790	COG3321	synthase
MID02_RS07795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS07795	COG0300	oxidoreductase activity
MID02_RS07795	COG3321	synthase
MID02_RS07795	COG4221	oxidoreductase activity
MID02_RS07800	COG4221	oxidoreductase activity
MID02_RS07800	COG3321	synthase
MID02_RS07800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS07800	COG0300	oxidoreductase activity
MID02_RS07805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS07805	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS07805	COG3321	synthase
MID02_RS07805	COG4221	oxidoreductase activity
MID02_RS07810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MID02_RS07815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MID02_RS07820	COG0022	dehydrogenase e1 component
MID02_RS07825	COG0508	dehydrogenase complex catalyzes the overall conversion of
MID02_RS07830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MID02_RS07835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID02_RS07850	COG1982	Orn Lys Arg decarboxylase major
MID02_RS07870	COG0483	inositol monophosphate 1-phosphatase activity
MID02_RS07880	COG3227	Zinc metalloprotease (Elastase)
MID02_RS07885	COG1595	DNA-templated transcription, initiation
MID02_RS07905	COG1217	gtp-binding protein TYPA
MID02_RS07915	COG4896	Protein conserved in bacteria
MID02_RS07925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MID02_RS07930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MID02_RS07935	COG2066	Belongs to the glutaminase family
MID02_RS07945	COG0772	Belongs to the SEDS family
MID02_RS07950	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MID02_RS07965	COG2010	Cytochrome c
MID02_RS07965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MID02_RS07970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MID02_RS07975	COG1845	cytochrome c oxidase, subunit III
MID02_RS07980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MID02_RS07985	COG3336	cytochrome c oxidase
MID02_RS07995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MID02_RS08000	COG2340	Cysteine-rich secretory protein family
MID02_RS08015	COG3679	Belongs to the UPF0342 family
MID02_RS08030	COG0742	ribosomal rna small subunit methyltransferase
MID02_RS08040	COG3314	Sporulation integral membrane protein YlbJ
MID02_RS08045	COG1752	Esterase of the alpha-beta hydrolase superfamily
MID02_RS08050	COG3480	Lon protease (S16) C-terminal proteolytic domain
MID02_RS08060	COG1399	metal-binding, possibly nucleic acid-binding protein
MID02_RS08080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MID02_RS08100	COG4839	cell division protein FtsL
MID02_RS08105	COG0768	penicillin binding
MID02_RS08110	COG0768	penicillin binding
MID02_RS08130	COG0772	Belongs to the SEDS family
MID02_RS08145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MID02_RS08150	COG0849	cell division
MID02_RS08155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MID02_RS08160	COG4412	M6 family metalloprotease domain protein
MID02_RS08160	COG1404	Belongs to the peptidase S8 family
MID02_RS08170	COG1191	sigma factor activity
MID02_RS08175	COG1191	sigma factor activity
MID02_RS08180	COG1119	ATPase activity
MID02_RS08185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MID02_RS08190	COG1873	PFAM PRC-barrel domain
MID02_RS08195	COG1496	oxidoreductase activity
MID02_RS08200	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MID02_RS08210	COG0762	integral membrane protein
MID02_RS08215	COG2302	S4 RNA-binding domain
MID02_RS08220	COG3599	regulation of cell shape
MID02_RS08225	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MID02_RS08230	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MID02_RS08240	COG0564	pseudouridine synthase activity
MID02_RS08250	COG2233	PERMEase
MID02_RS08260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MID02_RS08265	COG0505	Belongs to the CarA family
MID02_RS08270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MID02_RS08285	COG0284	orotidine-5'-phosphate decarboxylase activity
MID02_RS08290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MID02_RS08300	COG0306	phosphate transporter
MID02_RS08315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MID02_RS08320	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
MID02_RS08325	COG1648	precorrin-2 dehydrogenase activity
MID02_RS08335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MID02_RS08340	COG1561	YicC-like family, N-terminal region
MID02_RS08350	COG0194	GDP metabolic process
MID02_RS08360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MID02_RS08365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MID02_RS08370	COG0242	peptide deformylase activity
MID02_RS08380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MID02_RS08380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MID02_RS08390	COG0631	protein serine/threonine phosphatase activity
MID02_RS08395	COG0515	serine threonine protein kinase
MID02_RS08395	COG2815	serine threonine protein kinase
MID02_RS08405	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MID02_RS08410	COG1564	THIamine pyrophosphokinase
MID02_RS08425	COG1302	Protein conserved in bacteria
MID02_RS08430	COG1461	Dihydroxyacetone kinase
MID02_RS08435	COG1760	l-serine dehydratase
MID02_RS08440	COG1760	l-serine dehydratase
MID02_RS08445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MID02_RS08460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MID02_RS08465	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS08480	COG1196	nuclear chromosome segregation
MID02_RS08485	COG0552	protein localization to endoplasmic reticulum
MID02_RS08500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MID02_RS08510	COG1837	Belongs to the UPF0109 family
MID02_RS08535	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MID02_RS08550	COG2257	FlhB HrpN YscU SpaS Family
MID02_RS08560	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MID02_RS08565	COG0758	DNA mediated transformation
MID02_RS08570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MID02_RS08580	COG4974	Belongs to the 'phage' integrase family
MID02_RS08600	COG1815	bacterial-type flagellum-dependent cell motility
MID02_RS08605	COG1558	bacterial-type flagellum-dependent cell motility
MID02_RS08610	COG1677	Flagellar hook-basal body complex protein FliE
MID02_RS08615	COG1766	The M ring may be actively involved in energy transduction
MID02_RS08620	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MID02_RS08625	COG1317	bacterial-type flagellum organization
MID02_RS08630	COG1157	protein secretion by the type III secretion system
MID02_RS08635	COG2882	bacterial-type flagellum organization
MID02_RS08640	COG3334	PFAM MgtE intracellular
MID02_RS08645	COG3144	bacterial-type flagellum assembly
MID02_RS08650	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MID02_RS08655	COG4786	Flagellar basal body rod
MID02_RS08660	COG1582	Flagellar protein (FlbD)
MID02_RS08665	COG1580	Controls the rotational direction of flagella during chemotaxis
MID02_RS08670	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MID02_RS08675	COG1776	CheC inhibitor of MCP methylation
MID02_RS08675	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MID02_RS08680	COG2201	protein-glutamate methylesterase activity
MID02_RS08685	COG3190	flagellar
MID02_RS08690	COG1338	Plays a role in the flagellum-specific transport system
MID02_RS08695	COG1987	bacterial-type flagellum assembly
MID02_RS08700	COG1684	flagellar biosynthetic protein fliR
MID02_RS08705	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MID02_RS08710	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MID02_RS08715	COG1419	protein localization to endoplasmic reticulum
MID02_RS08720	COG0455	bacterial-type flagellum organization
MID02_RS08725	COG2201	protein-glutamate methylesterase activity
MID02_RS08730	COG2198	Histidine kinase
MID02_RS08730	COG0643	Histidine kinase
MID02_RS08735	COG0835	chemotaxis
MID02_RS08740	COG1776	CheC inhibitor of MCP methylation
MID02_RS08750	COG1191	sigma factor activity
MID02_RS08780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MID02_RS08785	COG4589	Belongs to the CDS family
MID02_RS08795	COG0750	zinc metalloprotease
MID02_RS08815	COG0195	Participates in both transcription termination and antitermination
MID02_RS08820	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MID02_RS08825	COG1358	cellular component organization or biogenesis
MID02_RS08835	COG1550	Protein conserved in bacteria
MID02_RS08850	COG0196	riboflavin kinase activity
MID02_RS08865	COG0726	polysaccharide deacetylase
MID02_RS08870	COG0612	Peptidase, M16
MID02_RS08875	COG1873	PFAM PRC-barrel domain
MID02_RS08880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MID02_RS08885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MID02_RS08890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MID02_RS08895	COG0527	aspartate kinase activity
MID02_RS08905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MID02_RS08910	COG0740	serine-type endopeptidase activity
MID02_RS08920	COG1674	ftsk spoiiie
MID02_RS08920	COG4980	gas vesicle protein
MID02_RS08925	COG2188	Transcriptional regulator
MID02_RS08930	COG2814	Major facilitator Superfamily
MID02_RS08935	COG1846	Transcriptional regulator
MID02_RS08940	COG1033	growth of symbiont in host cell
MID02_RS08940	COG2409	Drug exporters of the RND superfamily
MID02_RS08945	COG0612	Peptidase, M16
MID02_RS08950	COG0612	Peptidase, M16
MID02_RS08955	COG0300	oxidoreductase activity
MID02_RS08970	COG1426	Protein conserved in bacteria
MID02_RS08975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MID02_RS08990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MID02_RS09000	COG1692	metallophosphoesterase
MID02_RS09005	COG2359	stage V sporulation protein S
MID02_RS09025	COG4550	Control of competence regulator ComK, YlbF/YmcA
MID02_RS09065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS09070	COG3425	synthase
MID02_RS09075	COG1024	Enoyl-CoA hydratase
MID02_RS09080	COG1024	Enoyl-CoA hydratase
MID02_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS09085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS09085	COG3321	synthase
MID02_RS09085	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS09085	COG0300	oxidoreductase activity
MID02_RS09090	COG4221	oxidoreductase activity
MID02_RS09090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS09090	COG0300	oxidoreductase activity
MID02_RS09090	COG3321	synthase
MID02_RS09095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS09095	COG3321	synthase
MID02_RS09095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS09095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS09095	COG3321	synthase
MID02_RS09095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS09100	COG4221	oxidoreductase activity
MID02_RS09100	COG3321	synthase
MID02_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS09100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS09105	COG3321	synthase
MID02_RS09105	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MID02_RS09105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS09105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MID02_RS09110	COG2124	cytochrome p450
MID02_RS09115	COG3209	COG3209 Rhs family protein
MID02_RS09120	COG3619	membrane
MID02_RS09130	COG1404	Belongs to the peptidase S8 family
MID02_RS09140	COG4195	phage-related replication protein
MID02_RS09145	COG1764	response to oxidative stress
MID02_RS09155	COG2076	Multidrug Resistance protein
MID02_RS09195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MID02_RS09200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MID02_RS09205	COG4112	unkown
MID02_RS09210	COG0860	N-Acetylmuramoyl-L-alanine amidase
MID02_RS09215	COG0464	growth
MID02_RS09220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MID02_RS09225	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MID02_RS09230	COG0789	Transcriptional regulator
MID02_RS09235	COG0174	glutamine synthetase
MID02_RS09280	COG2211	Major facilitator Superfamily
MID02_RS09285	COG3507	Belongs to the glycosyl hydrolase 43 family
MID02_RS09300	COG1070	Carbohydrate kinase
MID02_RS09305	COG3848	Pyruvate phosphate dikinase
MID02_RS09305	COG0574	Belongs to the PEP-utilizing enzyme family
MID02_RS09325	COG2378	regulation of single-species biofilm formation
MID02_RS09330	COG2318	DinB family
MID02_RS09335	COG1064	alcohol dehydrogenase
MID02_RS09345	COG0456	acetyltransferase
MID02_RS09365	COG3397	chitin binding
MID02_RS09385	COG5434	Belongs to the glycosyl hydrolase 28 family
MID02_RS09390	COG0756	dUTP diphosphatase activity
MID02_RS09395	COG4195	phage-related replication protein
MID02_RS09430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MID02_RS09440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MID02_RS09460	COG0785	Cytochrome C biogenesis protein
MID02_RS09465	COG2201	protein-glutamate methylesterase activity
MID02_RS09470	COG4846	Membrane protein involved in cytochrome C biogenesis
MID02_RS09480	COG0071	Belongs to the small heat shock protein (HSP20) family
MID02_RS09495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MID02_RS09500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID02_RS09520	COG0824	Thioesterase
MID02_RS09530	COG4841	protein insertion into membrane
MID02_RS09540	COG1832	CoA-binding protein
MID02_RS09545	COG0187	DNA topoisomerase II activity
MID02_RS09550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MID02_RS09560	COG1115	amino acid carrier protein
MID02_RS09570	COG1063	alcohol dehydrogenase
MID02_RS09575	COG0800	Aldolase
MID02_RS09580	COG1312	Catalyzes the dehydration of D-mannonate
MID02_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS09590	COG1609	Transcriptional regulator
MID02_RS09595	COG2271	Major facilitator Superfamily
MID02_RS09635	COG2205	protein histidine kinase activity
MID02_RS09640	COG0745	RESPONSE REGULATOR receiver
MID02_RS09650	COG3507	Belongs to the glycosyl hydrolase 43 family
MID02_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS09680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MID02_RS09685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MID02_RS09690	COG2610	gluconate transmembrane transporter activity
MID02_RS09695	COG2124	cytochrome p450
MID02_RS09715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MID02_RS09725	COG2246	polysaccharide biosynthetic process
MID02_RS09730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MID02_RS09735	COG0586	Pfam SNARE associated Golgi protein
MID02_RS09740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MID02_RS09745	COG1024	Enoyl-CoA hydratase
MID02_RS09750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MID02_RS09755	COG0511	ligase activity, forming carbon-carbon bonds
MID02_RS09760	COG0439	Biotin carboxylase
MID02_RS09765	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS09770	COG1960	acyl-CoA dehydrogenase activity
MID02_RS09775	COG1649	PFAM Uncharacterised BCR, COG1649
MID02_RS09785	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MID02_RS09785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS09790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS09795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS09810	COG2027	D-alanyl-D-alanine carboxypeptidase
MID02_RS09815	COG2017	converts alpha-aldose to the beta-anomer
MID02_RS09820	COG0534	Mate efflux family protein
MID02_RS09835	COG0582	viral genome integration into host DNA
MID02_RS09840	COG0166	Belongs to the GPI family
MID02_RS09845	COG0405	Gamma-glutamyltransferase
MID02_RS09850	COG2814	Major facilitator Superfamily
MID02_RS09855	COG0640	Transcriptional regulator
MID02_RS09870	COG0604	alcohol dehydrogenase
MID02_RS09880	COG0493	'glutamate synthase
MID02_RS09885	COG0069	glutamate synthase activity
MID02_RS09885	COG0067	glutamate synthase
MID02_RS09885	COG0070	glutamate synthase
MID02_RS09890	COG0583	DNA-binding transcription factor activity
MID02_RS09895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MID02_RS09910	COG0300	oxidoreductase activity
MID02_RS09915	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MID02_RS09925	COG2814	Major facilitator Superfamily
MID02_RS09930	COG1070	Carbohydrate kinase
MID02_RS09935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MID02_RS09940	COG0243	molybdopterin cofactor binding
MID02_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS09965	COG1733	regulation of RNA biosynthetic process
MID02_RS09970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID02_RS09975	COG0662	Cupin 2, conserved barrel domain protein
MID02_RS09975	COG2207	Transcriptional regulator
MID02_RS09980	COG1309	transcriptional regulator
MID02_RS09985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MID02_RS09995	COG0640	Transcriptional regulator
MID02_RS10000	COG0741	lytic transglycosylase activity
MID02_RS10005	COG2322	membrane
MID02_RS10020	COG1619	proteins homologs of microcin C7 resistance protein MccF
MID02_RS10030	COG1388	LysM domain
MID02_RS10030	COG3584	3D domain protein
MID02_RS10035	COG0514	ATP-dependent DNA helicase (RecQ)
MID02_RS10045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MID02_RS10050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MID02_RS10065	COG0071	Belongs to the small heat shock protein (HSP20) family
MID02_RS10095	COG1012	belongs to the aldehyde dehydrogenase family
MID02_RS10100	COG1657	PFAM Prenyltransferase squalene oxidase
MID02_RS10105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MID02_RS10110	COG0733	neurotransmitter:sodium symporter activity
MID02_RS10115	COG0385	Bile acid
MID02_RS10120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MID02_RS10125	COG0508	dehydrogenase complex catalyzes the overall conversion of
MID02_RS10135	COG4548	von Willebrand factor, type A
MID02_RS10140	COG0714	Associated with various cellular activities
MID02_RS10145	COG2032	superoxide dismutase activity
MID02_RS10150	COG0791	NLP P60 protein
MID02_RS10150	COG1388	LysM domain
MID02_RS10155	COG1819	glycosyl
MID02_RS10160	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MID02_RS10165	COG0534	Mate efflux family protein
MID02_RS10170	COG1366	Belongs to the anti-sigma-factor antagonist family
MID02_RS10175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MID02_RS10180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MID02_RS10190	COG2962	Rard protein
MID02_RS10205	COG1942	4-Oxalocrotonate Tautomerase
MID02_RS10215	COG1733	regulation of RNA biosynthetic process
MID02_RS10220	COG0778	Nitroreductase
MID02_RS10225	COG0400	carboxylic ester hydrolase activity
MID02_RS10230	COG0346	lactoylglutathione lyase activity
MID02_RS10240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MID02_RS10250	COG2723	6-phospho-beta-galactosidase activity
MID02_RS10255	COG2188	Transcriptional regulator
MID02_RS10260	COG3409	Peptidoglycan-binding domain 1 protein
MID02_RS10260	COG0793	Belongs to the peptidase S41A family
MID02_RS10265	COG2226	methyltransferase
MID02_RS10275	COG1876	peptidase activity
MID02_RS10295	COG0671	phosphoesterase, PA-phosphatase related
MID02_RS10330	COG1509	lysine 2,3-aminomutase activity
MID02_RS10335	COG0456	acetyltransferase
MID02_RS10340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MID02_RS10345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MID02_RS10350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MID02_RS10355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MID02_RS10360	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MID02_RS10370	COG0456	acetyltransferase
MID02_RS10375	COG0463	Glycosyl transferase, family 2
MID02_RS10390	COG4641	Protein conserved in bacteria
MID02_RS10400	COG1086	Polysaccharide biosynthesis protein
MID02_RS10450	COG1388	LysM domain
MID02_RS10455	COG0457	Tetratricopeptide repeat
MID02_RS10510	COG5444	nuclease activity
MID02_RS10515	COG4282	regulation of fungal-type cell wall biogenesis
MID02_RS10550	COG1846	Transcriptional regulator
MID02_RS10555	COG4698	Protein conserved in bacteria
MID02_RS10560	COG2755	lipolytic protein G-D-S-L family
MID02_RS10565	COG1999	signal sequence binding
MID02_RS10575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MID02_RS10580	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MID02_RS10585	COG1272	protein, Hemolysin III
MID02_RS10590	COG0204	Acyl-transferase
MID02_RS10595	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MID02_RS10610	COG2136	Putative SAM-dependent methyltransferase
MID02_RS10610	COG2521	methyltransferase
MID02_RS10625	COG1413	lyase activity
MID02_RS10630	COG1418	mRNA catabolic process
MID02_RS10635	COG0386	Belongs to the glutathione peroxidase family
MID02_RS10645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MID02_RS10655	COG1278	Cold shock
MID02_RS10675	COG0328	RNA-DNA hybrid ribonuclease activity
MID02_RS10680	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MID02_RS10685	COG0328	RNA-DNA hybrid ribonuclease activity
MID02_RS10695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MID02_RS10710	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MID02_RS10720	COG1755	Isoprenylcysteine carboxyl methyltransferase
MID02_RS10725	COG3424	synthase
MID02_RS10750	COG1335	isochorismatase
MID02_RS10760	COG2233	PERMEase
MID02_RS10770	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MID02_RS10775	COG1199	ATP-dependent helicase activity
MID02_RS10790	COG0116	Belongs to the methyltransferase superfamily
MID02_RS10820	COG3359	exonuclease
MID02_RS10825	COG1111	helicase
MID02_RS10825	COG1205	dead DEAH box helicase
MID02_RS10830	COG2190	(PTS) system
MID02_RS10835	COG0071	Belongs to the small heat shock protein (HSP20) family
MID02_RS10875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MID02_RS10875	COG4499	WXG100 protein secretion system (Wss), protein YukC
MID02_RS10885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MID02_RS10890	COG3935	DnaD domain protein
MID02_RS10900	COG0436	Aminotransferase
MID02_RS10905	COG5353	protein conserved in bacteria
MID02_RS10915	COG1199	ATP-dependent helicase activity
MID02_RS10915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MID02_RS10945	COG0438	transferase activity, transferring glycosyl groups
MID02_RS10950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MID02_RS10965	COG1694	Mazg nucleotide pyrophosphohydrolase
MID02_RS10970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MID02_RS10975	COG2140	Oxalate decarboxylase
MID02_RS10985	COG4347	Protein of unknown function (DUF1405)
MID02_RS10990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MID02_RS10990	COG2010	Cytochrome c
MID02_RS10995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MID02_RS11000	COG0723	plastoquinol--plastocyanin reductase activity
MID02_RS11015	COG0457	Tetratricopeptide repeat
MID02_RS11025	COG0287	Prephenate dehydrogenase
MID02_RS11060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MID02_RS11065	COG4401	Chorismate mutase type I
MID02_RS11080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MID02_RS11085	COG0105	UTP biosynthetic process
MID02_RS11090	COG0142	geranyltranstransferase activity
MID02_RS11100	COG0142	geranyltranstransferase activity
MID02_RS11115	COG0776	regulation of translation
MID02_RS11120	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MID02_RS11160	COG0539	negative regulation of cytoplasmic translation
MID02_RS11175	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MID02_RS11180	COG2959	enzyme of heme biosynthesis
MID02_RS11185	COG3773	Cell wall hydrolase
MID02_RS11185	COG3409	Peptidoglycan-binding domain 1 protein
MID02_RS11190	COG2339	peptidase activity
MID02_RS11195	COG0492	ferredoxin-NADP+ reductase activity
MID02_RS11200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MID02_RS11205	COG4862	establishment of competence for transformation
MID02_RS11210	COG1408	metallophosphoesterase
MID02_RS11220	COG1388	LysM domain
MID02_RS11225	COG1266	CAAX protease self-immunity
MID02_RS11230	COG0514	ATP-dependent DNA helicase (RecQ)
MID02_RS11235	COG4955	Helix-turn-helix domain
MID02_RS11240	COG1141	Ferredoxin
MID02_RS11245	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MID02_RS11250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MID02_RS11260	COG1595	DNA-templated transcription, initiation
MID02_RS11265	COG5002	protein histidine kinase activity
MID02_RS11270	COG0745	RESPONSE REGULATOR receiver
MID02_RS11275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MID02_RS11280	COG1333	cytochrome c biogenesis protein
MID02_RS11285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID02_RS11290	COG1187	pseudouridine synthase activity
MID02_RS11295	COG0700	Nucleoside recognition
MID02_RS11300	COG2715	membrane protein required for spore maturation
MID02_RS11305	COG1686	Belongs to the peptidase S11 family
MID02_RS11330	COG1547	Domain of unknown function (DUF309)
MID02_RS11335	COG0456	acetyltransferase
MID02_RS11350	COG0307	riboflavin synthase, alpha
MID02_RS11355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MID02_RS11355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MID02_RS11365	COG0681	Belongs to the peptidase S26 family
MID02_RS11375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MID02_RS11380	COG4086	secreted protein
MID02_RS11385	COG0019	diaminopimelate decarboxylase activity
MID02_RS11390	COG0697	spore germination
MID02_RS11405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MID02_RS11425	COG1191	sigma factor activity
MID02_RS11435	COG1366	Belongs to the anti-sigma-factor antagonist family
MID02_RS11440	COG1686	Belongs to the peptidase S11 family
MID02_RS11445	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MID02_RS11450	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MID02_RS11455	COG4974	Belongs to the 'phage' integrase family
MID02_RS11465	COG0735	belongs to the Fur family
MID02_RS11470	COG1300	Membrane
MID02_RS11485	COG0281	malic enzyme
MID02_RS11490	COG1757	Na H antiporter
MID02_RS11495	COG1027	Aspartate ammonia-lyase
MID02_RS11500	COG0252	asparaginase activity
MID02_RS11505	COG1396	sequence-specific DNA binding
MID02_RS11510	COG1379	DNA repair
MID02_RS11515	COG0494	nUDIX hydrolase
MID02_RS11525	COG0667	Aldo Keto reductase
MID02_RS11535	COG1073	alpha beta
MID02_RS11545	COG4918	Iron-sulphur cluster biosynthesis
MID02_RS11550	COG0456	acetyltransferase
MID02_RS11550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MID02_RS11555	COG2329	Antibiotic biosynthesis monooxygenase
MID02_RS11560	COG0456	acetyltransferase
MID02_RS11565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MID02_RS11580	COG0628	permease
MID02_RS11590	COG0346	lactoylglutathione lyase activity
MID02_RS11600	COG3048	D-serine ammonia-lyase activity
MID02_RS11605	COG0300	oxidoreductase activity
MID02_RS11610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MID02_RS11615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MID02_RS11620	COG1024	Enoyl-CoA hydratase
MID02_RS11625	COG3425	synthase
MID02_RS11630	COG2124	cytochrome p450
MID02_RS11635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS11635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS11635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS11635	COG3321	synthase
MID02_RS11640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS11640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS11640	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS11640	COG3321	synthase
MID02_RS11640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS11645	COG0300	oxidoreductase activity
MID02_RS11645	COG3321	synthase
MID02_RS11645	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS11645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS11645	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS11650	COG0300	oxidoreductase activity
MID02_RS11650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS11650	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS11650	COG3321	synthase
MID02_RS11650	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS11655	COG3321	synthase
MID02_RS11655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS11655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS11655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS11660	COG0300	oxidoreductase activity
MID02_RS11660	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS11660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS11660	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS11660	COG3321	synthase
MID02_RS11665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS11665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS11665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS11665	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS11665	COG3321	synthase
MID02_RS11670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID02_RS11670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS11670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS11670	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS11670	COG3321	synthase
MID02_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS11680	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS11695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MID02_RS11695	COG2070	2-Nitropropane dioxygenase
MID02_RS11700	COG0250	Participates in transcription elongation, termination and antitermination
MID02_RS11720	COG0596	Alpha beta hydrolase
MID02_RS11735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MID02_RS11740	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MID02_RS11755	COG0706	membrane insertase activity
MID02_RS11760	COG2195	Cleaves the N-terminal amino acid of tripeptides
MID02_RS11765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MID02_RS11770	COG0346	lactoylglutathione lyase activity
MID02_RS11780	COG1376	ErfK ybiS ycfS ynhG family protein
MID02_RS11785	COG4129	membrane
MID02_RS11790	COG1126	abc transporter atp-binding protein
MID02_RS11795	COG0765	amino acid transport
MID02_RS11800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID02_RS11810	COG1597	lipid kinase activity
MID02_RS11815	COG0508	dehydrogenase complex catalyzes the overall conversion of
MID02_RS11820	COG0022	dehydrogenase e1 component
MID02_RS11825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MID02_RS11830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MID02_RS11835	COG3426	butyrate kinase activity
MID02_RS11840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MID02_RS11845	COG0280	phosphate acetyltransferase
MID02_RS11850	COG3290	protein histidine kinase activity
MID02_RS11850	COG3829	transcription factor binding
MID02_RS11860	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MID02_RS11865	COG2079	MmgE PrpD family protein
MID02_RS11870	COG0372	Belongs to the citrate synthase family
MID02_RS11875	COG1960	acyl-CoA dehydrogenase activity
MID02_RS11880	COG1250	3-hydroxyacyl-CoA dehydrogenase
MID02_RS11885	COG0183	Belongs to the thiolase family
MID02_RS11890	COG0584	glycerophosphoryl diester phosphodiesterase
MID02_RS11895	COG0860	N-Acetylmuramoyl-L-alanine amidase
MID02_RS11920	COG1902	pentaerythritol trinitrate reductase activity
MID02_RS11935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MID02_RS11940	COG0745	RESPONSE REGULATOR receiver
MID02_RS11945	COG0750	zinc metalloprotease
MID02_RS11950	COG0497	DNA recombination
MID02_RS11960	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MID02_RS11970	COG0142	geranyltranstransferase activity
MID02_RS11980	COG1570	exodeoxyribonuclease VII activity
MID02_RS11995	COG1302	Protein conserved in bacteria
MID02_RS12000	COG0439	Biotin carboxylase
MID02_RS12005	COG0511	ligase activity, forming carbon-carbon bonds
MID02_RS12045	COG3854	ATPases associated with a variety of cellular activities
MID02_RS12060	COG0006	proline dipeptidase activity
MID02_RS12070	COG3872	metal-dependent enzyme
MID02_RS12080	COG1752	Esterase of the alpha-beta hydrolase superfamily
MID02_RS12095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MID02_RS12115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MID02_RS12130	COG1396	sequence-specific DNA binding
MID02_RS12140	COG0681	Belongs to the peptidase S26 family
MID02_RS12165	COG4940	Competence protein ComGF
MID02_RS12175	COG4970	Tfp pilus assembly protein FimT
MID02_RS12180	COG4537	Required for transformation and DNA binding
MID02_RS12185	COG1459	type II secretion system
MID02_RS12190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MID02_RS12195	COG0598	Magnesium transport protein CorA
MID02_RS12200	COG1253	flavin adenine dinucleotide binding
MID02_RS12205	COG1366	Belongs to the anti-sigma-factor antagonist family
MID02_RS12215	COG1393	Belongs to the ArsC family
MID02_RS12225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MID02_RS12235	COG0011	TIGRFAM Protein of
MID02_RS12245	COG2866	Carboxypeptidase
MID02_RS12250	COG1940	carbohydrate kinase activity
MID02_RS12255	COG4483	Protein conserved in bacteria
MID02_RS12260	COG1757	Na H antiporter
MID02_RS12270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MID02_RS12285	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MID02_RS12290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MID02_RS12295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MID02_RS12300	COG0581	inorganic phosphate transmembrane transporter activity
MID02_RS12305	COG0573	inorganic phosphate transmembrane transporter activity
MID02_RS12310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MID02_RS12315	COG0768	penicillin binding
MID02_RS12320	COG0477	Major facilitator Superfamily
MID02_RS12325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MID02_RS12330	COG2839	Protein conserved in bacteria
MID02_RS12335	COG5521	maltodextrose utilization protein MalA
MID02_RS12340	COG1388	LysM domain
MID02_RS12350	COG4709	membrane
MID02_RS12355	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
MID02_RS12360	COG0735	belongs to the Fur family
MID02_RS12365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MID02_RS12380	COG0513	Belongs to the DEAD box helicase family
MID02_RS12395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MID02_RS12400	COG2384	SAM-dependent methyltransferase
MID02_RS12405	COG2010	Cytochrome c
MID02_RS12410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MID02_RS12415	COG0358	DNA primase activity
MID02_RS12430	COG0517	IMP dehydrogenase activity
MID02_RS12435	COG0751	glycine-tRNA ligase activity
MID02_RS12455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MID02_RS12460	COG0295	cytidine deaminase activity
MID02_RS12465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MID02_RS12475	COG1480	7TM receptor with intracellular HD hydrolase
MID02_RS12480	COG1702	phosphate starvation-inducible protein PhoH
MID02_RS12485	COG0561	phosphatase activity
MID02_RS12500	COG4864	UPF0365 protein
MID02_RS12505	COG1030	water channel activity
MID02_RS12510	COG1610	YqeY-like protein
MID02_RS12520	COG1283	sodium-dependent phosphate transmembrane transporter activity
MID02_RS12525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MID02_RS12530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MID02_RS12560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MID02_RS12575	COG0860	N-Acetylmuramoyl-L-alanine amidase
MID02_RS12605	COG0658	competence protein
MID02_RS12605	COG2333	competence protein COMEC
MID02_RS12610	COG2131	deaminase
MID02_RS12615	COG1596	polysaccharide export
MID02_RS12615	COG1555	photosystem II stabilization
MID02_RS12620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MID02_RS12625	COG2226	methyltransferase
MID02_RS12630	COG0799	negative regulation of ribosome biogenesis
MID02_RS12635	COG1713	HD superfamily hydrolase involved in NAD metabolism
MID02_RS12645	COG1534	Rna-binding protein
MID02_RS12650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MID02_RS12655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MID02_RS12660	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MID02_RS12670	COG2755	lipolytic protein G-D-S-L family
MID02_RS12680	COG0398	Pfam SNARE associated Golgi protein
MID02_RS12705	COG2207	Transcriptional regulator
MID02_RS12705	COG3708	Transcriptional regulator
MID02_RS12710	COG0563	adenylate kinase activity
MID02_RS12720	COG2814	Major facilitator Superfamily
MID02_RS12725	COG0456	acetyltransferase
MID02_RS12730	COG2318	DinB family
MID02_RS12740	COG0561	phosphatase activity
MID02_RS12745	COG0561	phosphatase activity
MID02_RS12755	COG1482	cell wall glycoprotein biosynthetic process
MID02_RS12760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID02_RS12760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID02_RS12760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID02_RS12765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID02_RS12765	COG3711	transcriptional antiterminator
MID02_RS12775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MID02_RS12780	COG0583	DNA-binding transcription factor activity
MID02_RS12785	COG2814	Major facilitator Superfamily
MID02_RS12790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MID02_RS12790	COG2124	cytochrome p450
MID02_RS12795	COG1309	transcriptional regulator
MID02_RS12800	COG2226	methyltransferase
MID02_RS12815	COG2116	formate transmembrane transporter activity
MID02_RS12820	COG5609	conserved protein (DUF2294)
MID02_RS12825	COG3383	formate dehydrogenase (NAD+) activity
MID02_RS12830	COG2427	Protein of unknown function (DUF1641)
MID02_RS12840	COG0626	cystathionine gamma-synthase activity
MID02_RS12845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MID02_RS12870	COG0768	penicillin binding
MID02_RS12885	COG0826	peptidase U32
MID02_RS12890	COG0826	peptidase U32
MID02_RS12895	COG4122	O-methyltransferase activity
MID02_RS12900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MID02_RS12915	COG4472	Bacterial protein of unknown function (DUF965)
MID02_RS12925	COG0628	permease
MID02_RS12930	COG1126	abc transporter atp-binding protein
MID02_RS12935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID02_RS12940	COG0765	amino acid transport
MID02_RS12945	COG0765	amino acid transport
MID02_RS12960	COG3881	PFAM PRC-barrel domain
MID02_RS12965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MID02_RS12970	COG0457	Tetratricopeptide repeat
MID02_RS12980	COG1104	cysteine desulfurase activity
MID02_RS12985	COG1959	2 iron, 2 sulfur cluster binding
MID02_RS12990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MID02_RS12995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MID02_RS13020	COG0860	N-Acetylmuramoyl-L-alanine amidase
MID02_RS13020	COG3103	Sh3 type 3 domain protein
MID02_RS13020	COG4991	sh3 domain protein
MID02_RS13030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MID02_RS13040	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MID02_RS13040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MID02_RS13045	COG5416	Lipopolysaccharide assembly protein A domain
MID02_RS13050	COG0490	domain, Protein
MID02_RS13055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MID02_RS13055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MID02_RS13065	COG2244	polysaccharide biosynthetic process
MID02_RS13070	COG2323	membrane
MID02_RS13080	COG1862	Preprotein translocase
MID02_RS13120	COG1388	LysM domain
MID02_RS13130	COG0157	Belongs to the NadC ModD family
MID02_RS13135	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MID02_RS13140	COG1104	cysteine desulfurase activity
MID02_RS13145	COG1827	regulation of RNA biosynthetic process
MID02_RS13150	COG0077	Prephenate dehydratase
MID02_RS13165	COG3290	protein histidine kinase activity
MID02_RS13170	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MID02_RS13175	COG2868	ribosomal protein
MID02_RS13185	COG1994	Peptidase M50
MID02_RS13190	COG0739	heme binding
MID02_RS13195	COG2894	cell division
MID02_RS13205	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MID02_RS13215	COG1077	Cell shape determining protein MreB Mrl
MID02_RS13235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MID02_RS13240	COG0285	dihydrofolate synthase activity
MID02_RS13245	COG0525	valine-tRNA ligase activity
MID02_RS13255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MID02_RS13260	COG1388	LysM domain
MID02_RS13270	COG0113	porphobilinogen synthase activity
MID02_RS13275	COG1587	Uroporphyrinogen-III synthase
MID02_RS13285	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MID02_RS13305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MID02_RS13310	COG0470	DNA polymerase III
MID02_RS13310	COG1067	ATP-dependent peptidase activity
MID02_RS13325	COG1477	protein flavinylation
MID02_RS13325	COG0457	Tetratricopeptide repeat
MID02_RS13340	COG0473	3-isopropylmalate dehydrogenase activity
MID02_RS13355	COG0440	acetolactate synthase activity
MID02_RS13360	COG0028	Belongs to the TPP enzyme family
MID02_RS13385	COG0622	Phosphoesterase
MID02_RS13390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MID02_RS13400	COG5401	PFAM Sporulation and spore germination
MID02_RS13410	COG1846	Transcriptional regulator
MID02_RS13415	COG2197	response regulator
MID02_RS13420	COG0824	Thioesterase
MID02_RS13425	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MID02_RS13430	COG1053	succinate dehydrogenase
MID02_RS13435	COG2009	succinate dehydrogenase
MID02_RS13440	COG1719	4-vinyl reductase, 4VR
MID02_RS13445	COG0527	aspartate kinase activity
MID02_RS13455	COG3118	belongs to the thioredoxin family
MID02_RS13460	COG3534	alpha-L-arabinofuranosidase
MID02_RS13465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MID02_RS13470	COG2086	electron transfer activity
MID02_RS13475	COG1024	Enoyl-CoA hydratase
MID02_RS13480	COG1309	transcriptional regulator
MID02_RS13485	COG0318	PFAM AMP-dependent synthetase and ligase
MID02_RS13495	COG3766	membrane
MID02_RS13505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MID02_RS13505	COG1796	DNA polymerase
MID02_RS13510	COG1286	toxin biosynthetic process
MID02_RS13525	COG0072	phenylalanine-tRNA ligase activity
MID02_RS13525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID02_RS13530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MID02_RS13535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MID02_RS13545	COG3835	regulator
MID02_RS13550	COG0277	FAD linked oxidase domain protein
MID02_RS13555	COG0247	lactate metabolic process
MID02_RS13560	COG1966	Carbon starvation protein
MID02_RS13565	COG3534	alpha-L-arabinofuranosidase
MID02_RS13570	COG0395	ABC-type sugar transport system, permease component
MID02_RS13575	COG1175	transmembrane transport
MID02_RS13580	COG1653	transport
MID02_RS13590	COG0647	UMP catabolic process
MID02_RS13595	COG0235	Class ii aldolase
MID02_RS13600	COG1069	ribulokinase activity
MID02_RS13605	COG2160	L-arabinose isomerase activity
MID02_RS13610	COG3507	Belongs to the glycosyl hydrolase 43 family
MID02_RS13615	COG1363	Peptidase, m42
MID02_RS13625	COG3326	Membrane
MID02_RS13630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MID02_RS13640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MID02_RS13645	COG1346	cytolysis
MID02_RS13650	COG1380	Effector of murein hydrolase LrgA
MID02_RS13655	COG3279	Response regulator of the LytR AlgR family
MID02_RS13660	COG3275	phosphorelay sensor kinase activity
MID02_RS13665	COG1011	Hydrolase
MID02_RS13680	COG0398	Pfam SNARE associated Golgi protein
MID02_RS13685	COG1484	DNA-dependent DNA replication
MID02_RS13690	COG3611	Membrane attachment protein
MID02_RS13705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MID02_RS13710	COG1733	regulation of RNA biosynthetic process
MID02_RS13715	COG2814	Major facilitator Superfamily
MID02_RS13720	COG0656	L-ascorbic acid biosynthetic process
MID02_RS13725	COG0237	dephospho-CoA kinase activity
MID02_RS13730	COG1971	Probably functions as a manganese efflux pump
MID02_RS13735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MID02_RS13740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MID02_RS13740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MID02_RS13745	COG5002	protein histidine kinase activity
MID02_RS13750	COG0745	RESPONSE REGULATOR receiver
MID02_RS13760	COG0538	isocitrate dehydrogenase activity
MID02_RS13765	COG0372	Belongs to the citrate synthase family
MID02_RS13785	COG0628	permease
MID02_RS13790	COG3030	protein affecting phage T7 exclusion by the F plasmid
MID02_RS13795	COG0469	pyruvate kinase activity
MID02_RS13815	COG0281	malic enzyme
MID02_RS13820	COG0587	DNA-directed DNA polymerase activity
MID02_RS13840	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MID02_RS13850	COG4109	DRTGG domain
MID02_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS13875	COG0521	Mo-molybdopterin cofactor biosynthetic process
MID02_RS13885	COG0827	DNA restriction-modification system
MID02_RS13890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MID02_RS13895	COG3874	Sporulation protein YtfJ
MID02_RS13905	COG1714	RDD family
MID02_RS13910	COG0616	signal peptide processing
MID02_RS13915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MID02_RS13920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MID02_RS13925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MID02_RS13940	COG1104	cysteine desulfurase activity
MID02_RS13945	COG1114	Component of the transport system for branched-chain amino acids
MID02_RS13955	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MID02_RS13960	COG1309	transcriptional regulator
MID02_RS13965	COG1956	GAF domain-containing protein
MID02_RS13970	COG2203	Gaf domain
MID02_RS13970	COG2199	diguanylate cyclase activity
MID02_RS13980	COG1012	belongs to the aldehyde dehydrogenase family
MID02_RS13985	COG4282	regulation of fungal-type cell wall biogenesis
MID02_RS13990	COG1017	nitric oxide dioxygenase activity
MID02_RS13990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MID02_RS14000	COG0693	protein deglycase activity
MID02_RS14015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MID02_RS14020	COG1378	Sugar-specific transcriptional regulator TrmB
MID02_RS14040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MID02_RS14045	COG0454	-acetyltransferase
MID02_RS14050	COG0517	IMP dehydrogenase activity
MID02_RS14055	COG0123	including yeast histone deacetylase and acetoin utilization protein
MID02_RS14060	COG1360	Flagellar Motor Protein
MID02_RS14065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MID02_RS14070	COG1609	Transcriptional regulator
MID02_RS14075	COG1605	Chorismate mutase
MID02_RS14075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MID02_RS14080	COG3118	belongs to the thioredoxin family
MID02_RS14085	COG4980	gas vesicle protein
MID02_RS14090	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MID02_RS14100	COG1674	ftsk spoiiie
MID02_RS14105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID02_RS14115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID02_RS14125	COG1363	Peptidase, m42
MID02_RS14130	COG5584	Small secreted protein
MID02_RS14135	COG0281	malic enzyme
MID02_RS14140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MID02_RS14155	COG0510	thiamine kinase activity
MID02_RS14160	COG1597	lipid kinase activity
MID02_RS14170	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MID02_RS14175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MID02_RS14180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MID02_RS14185	COG2252	PERMEase
MID02_RS14190	COG4473	ABC transporter
MID02_RS14195	COG1131	(ABC) transporter
MID02_RS14200	COG1349	DNA-binding transcription factor activity
MID02_RS14205	COG1187	pseudouridine synthase activity
MID02_RS14210	COG2244	polysaccharide biosynthetic process
MID02_RS14215	COG2081	HI0933 family
MID02_RS14220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MID02_RS14230	COG1609	Transcriptional regulator
MID02_RS14235	COG1653	transport
MID02_RS14240	COG1175	transmembrane transport
MID02_RS14245	COG0395	ABC-type sugar transport system, permease component
MID02_RS14250	COG1486	melibiose metabolic process
MID02_RS14260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MID02_RS14275	COG2202	Pas domain
MID02_RS14275	COG1366	Belongs to the anti-sigma-factor antagonist family
MID02_RS14280	COG2814	Major facilitator Superfamily
MID02_RS14285	COG5522	Integral membrane protein (intg_mem_TP0381)
MID02_RS14290	COG0577	efflux transmembrane transporter activity
MID02_RS14295	COG1136	(ABC) transporter
MID02_RS14300	COG2205	protein histidine kinase activity
MID02_RS14305	COG0745	RESPONSE REGULATOR receiver
MID02_RS14310	COG0577	efflux transmembrane transporter activity
MID02_RS14315	COG1136	(ABC) transporter
MID02_RS14335	COG1131	(ABC) transporter
MID02_RS14340	COG1725	Transcriptional regulator
MID02_RS14355	COG1242	4 iron, 4 sulfur cluster binding
MID02_RS14360	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MID02_RS14370	COG0584	glycerophosphoryl diester phosphodiesterase
MID02_RS14380	COG2267	carboxylic ester hydrolase activity
MID02_RS14385	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MID02_RS14390	COG1113	amino acid transport
MID02_RS14395	COG0367	asparagine synthase
MID02_RS14415	COG1506	peptidase
MID02_RS14420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MID02_RS14425	COG1116	anion transmembrane transporter activity
MID02_RS14430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MID02_RS14435	COG0494	nUDIX hydrolase
MID02_RS14440	COG4824	toxin secretion phage lysis holin
MID02_RS14445	COG0783	Belongs to the Dps family
MID02_RS14470	COG0288	reversible hydration of carbon dioxide
MID02_RS14480	COG1271	oxidase subunit
MID02_RS14485	COG1294	oxidase, subunit
MID02_RS14495	COG4948	Mandelate Racemase Muconate Lactonizing
MID02_RS14505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MID02_RS14510	COG0596	Alpha beta hydrolase
MID02_RS14520	COG1169	isochorismate synthase
MID02_RS14525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MID02_RS14530	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MID02_RS14655	COG3859	Proton-coupled thiamine transporter YuaJ
MID02_RS14660	COG2268	Band 7 protein
MID02_RS14665	COG1585	Membrane protein implicated in regulation of membrane protease activity
MID02_RS14670	COG2318	DinB family
MID02_RS14680	COG1454	alcohol dehydrogenase
MID02_RS14685	COG1012	belongs to the aldehyde dehydrogenase family
MID02_RS14690	COG1510	regulation of RNA biosynthetic process
MID02_RS14700	COG0569	domain protein
MID02_RS14705	COG1705	Flagellar rod assembly protein muramidase FlgJ
MID02_RS14710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MID02_RS14710	COG1017	nitric oxide dioxygenase activity
MID02_RS14755	COG0628	permease
MID02_RS14760	COG0673	inositol 2-dehydrogenase activity
MID02_RS14765	COG0693	protein deglycase activity
MID02_RS14770	COG0840	transmembrane signaling receptor activity
MID02_RS14775	COG0840	transmembrane signaling receptor activity
MID02_RS14780	COG0840	transmembrane signaling receptor activity
MID02_RS14785	COG0840	transmembrane signaling receptor activity
MID02_RS14800	COG2070	2-Nitropropane dioxygenase
MID02_RS14810	COG0366	Alpha amylase catalytic
MID02_RS14815	COG1253	flavin adenine dinucleotide binding
MID02_RS14820	COG2738	Putative neutral zinc metallopeptidase
MID02_RS14835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MID02_RS14860	COG1335	isochorismatase
MID02_RS14865	COG1979	alcohol dehydrogenase
MID02_RS14870	COG1979	alcohol dehydrogenase
MID02_RS14875	COG2155	Conserved Protein
MID02_RS14880	COG1098	S1 RNA binding domain
MID02_RS14885	COG0436	Aminotransferase
MID02_RS14890	COG1522	sequence-specific DNA binding
MID02_RS14895	COG2267	carboxylic ester hydrolase activity
MID02_RS14905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MID02_RS14910	COG2205	protein histidine kinase activity
MID02_RS14920	COG5018	Exonuclease
MID02_RS14925	COG2814	Major facilitator Superfamily
MID02_RS14930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MID02_RS14935	COG3011	Protein conserved in bacteria
MID02_RS14945	COG3290	protein histidine kinase activity
MID02_RS14950	COG4565	transcriptional regulatory protein
MID02_RS14955	COG1744	ABC transporter substrate-binding protein PnrA-like
MID02_RS14960	COG3845	ABC transporter
MID02_RS14965	COG4603	Belongs to the binding-protein-dependent transport system permease family
MID02_RS14970	COG1079	Belongs to the binding-protein-dependent transport system permease family
MID02_RS14980	COG2111	Na H antiporter
MID02_RS14980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MID02_RS14985	COG2111	Na H antiporter
MID02_RS14990	COG1006	Multisubunit Na H antiporter MnhC subunit
MID02_RS14995	COG0651	ATP synthesis coupled electron transport
MID02_RS15000	COG1863	multisubunit Na H antiporter MnhE subunit
MID02_RS15005	COG2212	antiporter activity
MID02_RS15010	COG1320	monovalent cation:proton antiporter activity
MID02_RS15015	COG2050	protein possibly involved in aromatic compounds catabolism
MID02_RS15020	COG2197	response regulator
MID02_RS15025	COG4585	Histidine kinase
MID02_RS15035	COG0142	geranyltranstransferase activity
MID02_RS15050	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MID02_RS15055	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MID02_RS15060	COG1335	isochorismatase
MID02_RS15065	COG5506	Protein of unknown function (DUF1694)
MID02_RS15080	COG0628	permease
MID02_RS15090	COG1418	mRNA catabolic process
MID02_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS15105	COG1511	domain protein
MID02_RS15115	COG4499	WXG100 protein secretion system (Wss), protein YukC
MID02_RS15120	COG5417	Belongs to the EsaB family
MID02_RS15125	COG4842	Belongs to the WXG100 family
MID02_RS15130	COG2508	Transcriptional regulator
MID02_RS15130	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MID02_RS15135	COG0686	Belongs to the AlaDH PNT family
MID02_RS15140	COG5634	Uncharacterized conserved protein (DUF2278)
MID02_RS15145	COG3251	PFAM MbtH domain protein
MID02_RS15150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID02_RS15155	COG1535	isochorismatase
MID02_RS15155	COG3433	isochorismatase activity
MID02_RS15160	COG1021	2,3-dihydroxybenzoate-AMP ligase
MID02_RS15165	COG1169	isochorismate synthase
MID02_RS15170	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS15175	COG2819	hydrolase of the alpha beta superfamily
MID02_RS15180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MID02_RS15185	COG1268	BioY protein
MID02_RS15190	COG2056	Na+-H+ antiporter family
MID02_RS15200	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MID02_RS15205	COG3584	3D domain protein
MID02_RS15220	COG1252	NADH dehydrogenase
MID02_RS15250	COG1131	(ABC) transporter
MID02_RS15275	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MID02_RS15280	COG0316	Belongs to the HesB IscA family
MID02_RS15290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MID02_RS15300	COG1252	NADH dehydrogenase
MID02_RS15305	COG4837	Protein of unknown function (DUF1462)
MID02_RS15310	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MID02_RS15315	COG4946	Tricorn protease homolog
MID02_RS15315	COG1506	peptidase
MID02_RS15315	COG0823	Involved in the tonB-independent uptake of proteins
MID02_RS15325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MID02_RS15330	COG0460	homoserine dehydrogenase
MID02_RS15335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MID02_RS15340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MID02_RS15345	COG0647	UMP catabolic process
MID02_RS15350	COG2445	Protein of unknown function DUF86
MID02_RS15355	COG4470	Protein conserved in bacteria
MID02_RS15365	COG0739	heme binding
MID02_RS15375	COG0737	Belongs to the 5'-nucleotidase family
MID02_RS15380	COG0730	response to heat
MID02_RS15385	COG1801	Protein of unknown function DUF72
MID02_RS15400	COG2508	Transcriptional regulator
MID02_RS15430	COG2814	Major facilitator Superfamily
MID02_RS15435	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MID02_RS15440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MID02_RS15445	COG2356	endonuclease I
MID02_RS15450	COG3842	ATPase activity
MID02_RS15455	COG2188	Transcriptional regulator
MID02_RS15460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MID02_RS15465	COG0395	ABC-type sugar transport system, permease component
MID02_RS15470	COG1175	transmembrane transport
MID02_RS15475	COG1653	transport
MID02_RS15480	COG2222	sugar isomerase
MID02_RS15485	COG0789	Transcriptional regulator
MID02_RS15495	COG0322	excinuclease ABC activity
MID02_RS15500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MID02_RS15505	COG2226	methyltransferase
MID02_RS15515	COG3409	Peptidoglycan-binding domain 1 protein
MID02_RS15520	COG0719	Fe-S assembly protein
MID02_RS15525	COG0822	iron-sulfur transferase activity
MID02_RS15530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MID02_RS15535	COG0719	Fe-S assembly protein
MID02_RS15540	COG0396	ATPase activity
MID02_RS15550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MID02_RS15555	COG1464	Belongs to the NlpA lipoprotein family
MID02_RS15560	COG2011	ABC-type metal ion transport system permease component
MID02_RS15565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MID02_RS15575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID02_RS15580	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MID02_RS15595	COG1393	Belongs to the ArsC family
MID02_RS15600	COG1960	acyl-CoA dehydrogenase activity
MID02_RS15605	COG0183	Belongs to the thiolase family
MID02_RS15610	COG1024	Enoyl-CoA hydratase
MID02_RS15610	COG1250	3-hydroxyacyl-CoA dehydrogenase
MID02_RS15630	COG5577	PFAM Coat F domain
MID02_RS15635	COG1846	Transcriptional regulator
MID02_RS15640	COG0477	Major facilitator Superfamily
MID02_RS15645	COG0583	DNA-binding transcription factor activity
MID02_RS15665	COG1120	ATPase activity
MID02_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS15685	COG0783	Belongs to the Dps family
MID02_RS15690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MID02_RS15695	COG0745	RESPONSE REGULATOR receiver
MID02_RS15700	COG2205	protein histidine kinase activity
MID02_RS15700	COG2770	Histidine kinase
MID02_RS15710	COG1309	transcriptional regulator
MID02_RS15715	COG0114	fumarate hydratase activity
MID02_RS15725	COG0697	spore germination
MID02_RS15730	COG0814	amino acid
MID02_RS15740	COG2197	response regulator
MID02_RS15745	COG4585	Histidine kinase
MID02_RS15750	COG4758	membrane
MID02_RS15755	COG3595	metallopeptidase activity
MID02_RS15760	COG1842	Phage shock protein A
MID02_RS15765	COG4758	membrane
MID02_RS15770	COG2814	Major facilitator Superfamily
MID02_RS15775	COG2096	Adenosyltransferase
MID02_RS15780	COG1120	ATPase activity
MID02_RS15785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID02_RS15790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MID02_RS15795	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS15800	COG3386	PFAM SMP-30 Gluconolaconase
MID02_RS15805	COG2205	protein histidine kinase activity
MID02_RS15810	COG0745	RESPONSE REGULATOR receiver
MID02_RS15820	COG1191	sigma factor activity
MID02_RS15830	COG2140	Oxalate decarboxylase
MID02_RS15840	COG1120	ATPase activity
MID02_RS15845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID02_RS15850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID02_RS15855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MID02_RS15860	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MID02_RS15865	COG0531	amino acid
MID02_RS15875	COG1988	membrane-bound metal-dependent
MID02_RS15880	COG1368	sulfuric ester hydrolase activity
MID02_RS15885	COG1910	domain protein
MID02_RS15890	COG0725	ABC transporter, periplasmic molybdate-binding protein
MID02_RS15895	COG4149	molybdate abc transporter
MID02_RS15900	COG2197	response regulator
MID02_RS15905	COG3850	Histidine kinase
MID02_RS15910	COG1131	(ABC) transporter
MID02_RS15920	COG0842	Transport permease protein
MID02_RS15925	COG0656	L-ascorbic acid biosynthetic process
MID02_RS15945	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MID02_RS15950	COG3973	AAA domain
MID02_RS15955	COG2860	membrane
MID02_RS15965	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MID02_RS15970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MID02_RS15975	COG2217	Heavy metal translocating P-type atpase
MID02_RS15980	COG2217	Heavy metal translocating P-type atpase
MID02_RS15985	COG2608	mercury ion transmembrane transporter activity
MID02_RS15990	COG1937	Protein conserved in bacteria
MID02_RS15995	COG0673	inositol 2-dehydrogenase activity
MID02_RS16005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MID02_RS16010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MID02_RS16015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MID02_RS16020	COG1126	abc transporter atp-binding protein
MID02_RS16025	COG0765	amino acid transport
MID02_RS16030	COG0765	amino acid transport
MID02_RS16035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID02_RS16040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID02_RS16045	COG0454	-acetyltransferase
MID02_RS16050	COG0583	DNA-binding transcription factor activity
MID02_RS16055	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS16060	COG2732	(Barnase) inhibitor
MID02_RS16070	COG5632	N-Acetylmuramoyl-L-alanine amidase
MID02_RS16075	COG4824	toxin secretion phage lysis holin
MID02_RS16095	COG5434	Belongs to the glycosyl hydrolase 28 family
MID02_RS16110	COG5412	phage tail tape measure protein
MID02_RS16110	COG3953	SLT domain
MID02_RS16190	COG0582	viral genome integration into host DNA
MID02_RS16195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MID02_RS16300	COG0582	viral genome integration into host DNA
MID02_RS16310	COG5632	N-Acetylmuramoyl-L-alanine amidase
MID02_RS16315	COG4824	toxin secretion phage lysis holin
MID02_RS16335	COG5434	Belongs to the glycosyl hydrolase 28 family
MID02_RS16350	COG5412	phage tail tape measure protein
MID02_RS16350	COG3953	SLT domain
MID02_RS16430	COG0582	viral genome integration into host DNA
MID02_RS16435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MID02_RS16540	COG0582	viral genome integration into host DNA
MID02_RS16555	COG0557	exoribonuclease II activity
MID02_RS16560	COG1647	Serine aminopeptidase, S33
MID02_RS16565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MID02_RS16570	COG1476	TRANSCRIPTIONal
MID02_RS16575	COG1396	sequence-specific DNA binding
MID02_RS16580	COG1396	sequence-specific DNA binding
MID02_RS16585	COG1733	regulation of RNA biosynthetic process
MID02_RS16610	COG1131	(ABC) transporter
MID02_RS16615	COG1174	glycine betaine transport
MID02_RS16620	COG1732	Glycine betaine
MID02_RS16625	COG1174	glycine betaine transport
MID02_RS16630	COG0517	IMP dehydrogenase activity
MID02_RS16630	COG1125	glycine betaine transport
MID02_RS16635	COG1510	regulation of RNA biosynthetic process
MID02_RS16640	COG1174	glycine betaine transport
MID02_RS16645	COG1732	Glycine betaine
MID02_RS16650	COG1174	glycine betaine transport
MID02_RS16655	COG1125	glycine betaine transport
MID02_RS16655	COG0517	IMP dehydrogenase activity
MID02_RS16660	COG1510	regulation of RNA biosynthetic process
MID02_RS16665	COG2095	MarC family integral membrane protein
MID02_RS16670	COG3064	Membrane
MID02_RS16675	COG4640	response to antibiotic
MID02_RS16680	COG0456	acetyltransferase
MID02_RS16695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MID02_RS16710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MID02_RS16715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MID02_RS16720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MID02_RS16730	COG2234	aminopeptidase activity
MID02_RS16750	COG0126	phosphoglycerate kinase activity
MID02_RS16755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MID02_RS16760	COG2390	Transcriptional regulator
MID02_RS16765	COG2814	Major facilitator Superfamily
MID02_RS16770	COG1609	Transcriptional regulator
MID02_RS16775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MID02_RS16785	COG0583	DNA-binding transcription factor activity
MID02_RS16790	COG0697	spore germination
MID02_RS16795	COG1113	amino acid transport
MID02_RS16800	COG1737	Transcriptional regulator
MID02_RS16805	COG1070	Carbohydrate kinase
MID02_RS16830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MID02_RS16835	COG2186	Transcriptional regulator
MID02_RS16840	COG1620	l-lactate permease
MID02_RS16845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MID02_RS16855	COG5039	Polysaccharide pyruvyl transferase
MID02_RS16860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MID02_RS16865	COG0110	maltose O-acetyltransferase activity
MID02_RS16870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MID02_RS16875	COG2244	polysaccharide biosynthetic process
MID02_RS16880	COG1216	Glycosyl transferase, family 2
MID02_RS16885	COG5039	Polysaccharide pyruvyl transferase
MID02_RS16890	COG1216	Glycosyl transferase, family 2
MID02_RS16900	COG0438	transferase activity, transferring glycosyl groups
MID02_RS16905	COG1215	transferase activity, transferring glycosyl groups
MID02_RS16910	COG0438	transferase activity, transferring glycosyl groups
MID02_RS16915	COG1086	Polysaccharide biosynthesis protein
MID02_RS16920	COG0489	protein tyrosine kinase activity
MID02_RS16925	COG3944	biosynthesis protein
MID02_RS16930	COG1396	sequence-specific DNA binding
MID02_RS16935	COG2272	Belongs to the type-B carboxylesterase lipase family
MID02_RS16945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MID02_RS16950	COG2364	Membrane
MID02_RS16955	COG0456	acetyltransferase
MID02_RS16960	COG3479	Phenolic acid decarboxylase
MID02_RS17020	COG2223	nitrite transmembrane transporter activity
MID02_RS17025	COG1609	Transcriptional regulator
MID02_RS17035	COG0583	DNA-binding transcription factor activity
MID02_RS17040	COG2828	Protein conserved in bacteria
MID02_RS17045	COG0477	Major facilitator Superfamily
MID02_RS17045	COG2814	Major facilitator Superfamily
MID02_RS17050	COG1611	Belongs to the LOG family
MID02_RS17055	COG1694	Mazg nucleotide pyrophosphohydrolase
MID02_RS17060	COG0659	secondary active sulfate transmembrane transporter activity
MID02_RS17065	COG0288	reversible hydration of carbon dioxide
MID02_RS17070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MID02_RS17075	COG4290	ribonuclease
MID02_RS17080	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MID02_RS17085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID02_RS17095	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MID02_RS17105	COG1051	belongs to the nudix hydrolase family
MID02_RS17110	COG0492	ferredoxin-NADP+ reductase activity
MID02_RS17115	COG3883	PFAM NLP P60 protein
MID02_RS17115	COG0791	NLP P60 protein
MID02_RS17120	COG0457	Tetratricopeptide repeat
MID02_RS17125	COG5002	protein histidine kinase activity
MID02_RS17130	COG0745	RESPONSE REGULATOR receiver
MID02_RS17140	COG1132	(ABC) transporter
MID02_RS17145	COG0140	phosphoribosyl-ATP diphosphatase activity
MID02_RS17145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MID02_RS17170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MID02_RS17185	COG4990	cell redox homeostasis
MID02_RS17190	COG0110	maltose O-acetyltransferase activity
MID02_RS17210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MID02_RS17220	COG2188	Transcriptional regulator
MID02_RS17225	COG1309	transcriptional regulator
MID02_RS17230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MID02_RS17235	COG1950	PFAM Membrane protein of
MID02_RS17240	COG1983	PspC domain protein
MID02_RS17245	COG3595	metallopeptidase activity
MID02_RS17260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MID02_RS17270	COG4897	Protein conserved in bacteria
MID02_RS17275	COG0574	Belongs to the PEP-utilizing enzyme family
MID02_RS17275	COG3848	Pyruvate phosphate dikinase
MID02_RS17280	COG1309	transcriptional regulator
MID02_RS17285	COG2814	Major facilitator Superfamily
MID02_RS17295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MID02_RS17305	COG0793	Belongs to the peptidase S41A family
MID02_RS17305	COG3409	Peptidoglycan-binding domain 1 protein
MID02_RS17310	COG3420	alginic acid biosynthetic process
MID02_RS17315	COG2177	Part of the ABC transporter FtsEX involved in
MID02_RS17320	COG2884	Cell division ATP-binding protein ftsE
MID02_RS17325	COG2010	Cytochrome c
MID02_RS17330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MID02_RS17345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MID02_RS17360	COG1516	flagellar protein fliS
MID02_RS17365	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MID02_RS17370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MID02_RS17390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MID02_RS17395	COG4786	Flagellar basal body rod
MID02_RS17395	COG1256	bacterial-type flagellum assembly
MID02_RS17400	COG3418	PFAM FlgN family protein
MID02_RS17405	COG2747	anti-sigma28 factor FlgM
MID02_RS17415	COG1040	competence protein
MID02_RS17425	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MID02_RS17430	COG1307	EDD domain protein, DegV family
MID02_RS17435	COG2197	response regulator
MID02_RS17440	COG4585	Histidine kinase
MID02_RS17445	COG1739	Uncharacterized protein family UPF0029
MID02_RS17450	COG1316	TRANSCRIPTIONal
MID02_RS17455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MID02_RS17460	COG0438	transferase activity, transferring glycosyl groups
MID02_RS17465	COG1215	transferase activity, transferring glycosyl groups
MID02_RS17470	COG3206	protein involved in exopolysaccharide biosynthesis
MID02_RS17475	COG3307	-O-antigen
MID02_RS17480	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MID02_RS17485	COG0297	glycogen (starch) synthase activity
MID02_RS17485	COG0438	transferase activity, transferring glycosyl groups
MID02_RS17490	COG2244	polysaccharide biosynthetic process
MID02_RS17500	COG0860	N-Acetylmuramoyl-L-alanine amidase
MID02_RS17500	COG2247	cell wall binding repeat
MID02_RS17505	COG2247	cell wall binding repeat
MID02_RS17505	COG2385	sporulation resulting in formation of a cellular spore
MID02_RS17515	COG1316	TRANSCRIPTIONal
MID02_RS17520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MID02_RS17525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MID02_RS17530	COG1134	teichoic acid transport
MID02_RS17535	COG1682	transport, permease protein
MID02_RS17540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MID02_RS17550	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MID02_RS17555	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MID02_RS17560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MID02_RS17565	COG4193	domain, Protein
MID02_RS17570	COG1482	cell wall glycoprotein biosynthetic process
MID02_RS17575	COG0697	spore germination
MID02_RS17580	COG0814	amino acid
MID02_RS17590	COG1215	transferase activity, transferring glycosyl groups
MID02_RS17595	COG2814	Major facilitator Superfamily
MID02_RS17600	COG1316	TRANSCRIPTIONal
MID02_RS17605	COG0561	phosphatase activity
MID02_RS17610	COG2433	Pfam Transposase IS66
MID02_RS17615	COG0791	NLP P60 protein
MID02_RS17625	COG2843	Capsule synthesis protein
MID02_RS17635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MID02_RS17640	COG0697	spore germination
MID02_RS17645	COG0814	amino acid
MID02_RS17655	COG1609	Transcriptional regulator
MID02_RS17660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MID02_RS17670	COG1129	ABC transporter
MID02_RS17675	COG1172	Belongs to the binding-protein-dependent transport system permease family
MID02_RS17680	COG1879	ABC-type sugar transport system periplasmic component
MID02_RS17685	COG3103	Sh3 type 3 domain protein
MID02_RS17690	COG2249	NAD(P)H dehydrogenase (quinone) activity
MID02_RS17695	COG3527	Alpha-acetolactate decarboxylase
MID02_RS17700	COG0028	Belongs to the TPP enzyme family
MID02_RS17705	COG0583	DNA-binding transcription factor activity
MID02_RS17710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MID02_RS17725	COG5337	Spore coat protein CotH
MID02_RS17735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MID02_RS17745	COG0405	Gamma-glutamyltransferase
MID02_RS17750	COG1522	sequence-specific DNA binding
MID02_RS17755	COG2059	Chromate
MID02_RS17760	COG2059	Chromate
MID02_RS17770	COG0655	NAD(P)H dehydrogenase (quinone) activity
MID02_RS17775	COG0583	DNA-binding transcription factor activity
MID02_RS17795	COG5444	nuclease activity
MID02_RS17810	COG3878	Protein conserved in bacteria
MID02_RS17815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MID02_RS17820	COG4464	protein tyrosine phosphatase activity
MID02_RS17825	COG0489	protein tyrosine kinase activity
MID02_RS17830	COG3944	biosynthesis protein
MID02_RS17840	COG4715	Zinc finger, swim domain protein
MID02_RS17845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MID02_RS17850	COG0561	phosphatase activity
MID02_RS17855	COG1349	DNA-binding transcription factor activity
MID02_RS17860	COG0629	single-stranded DNA binding
MID02_RS17885	COG0457	Tetratricopeptide repeat
MID02_RS17890	COG4786	Flagellar basal body rod
MID02_RS17895	COG4786	Flagellar basal body rod
MID02_RS17900	COG1077	Cell shape determining protein MreB Mrl
MID02_RS17905	COG1609	Transcriptional regulator
MID02_RS17910	COG1846	Transcriptional regulator
MID02_RS17915	COG2814	Major facilitator Superfamily
MID02_RS17920	COG1953	Uracil, thiamine, allantoin
MID02_RS17925	COG0477	Major facilitator Superfamily
MID02_RS17930	COG1335	isochorismatase
MID02_RS17935	COG0004	ammonium transporteR
MID02_RS17940	COG0347	Belongs to the P(II) protein family
MID02_RS17945	COG0772	Belongs to the SEDS family
MID02_RS17950	COG0671	phosphoesterase, PA-phosphatase related
MID02_RS17960	COG0739	heme binding
MID02_RS17965	COG1247	-acetyltransferase
MID02_RS17980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MID02_RS17995	COG0726	polysaccharide deacetylase
MID02_RS18005	COG1959	2 iron, 2 sulfur cluster binding
MID02_RS18020	COG0831	urea catabolic process
MID02_RS18025	COG3237	CsbD-like
MID02_RS18030	COG1994	Peptidase M50
MID02_RS18035	COG0457	Tetratricopeptide repeat
MID02_RS18045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MID02_RS18055	COG2304	oxidoreductase activity
MID02_RS18060	COG2304	oxidoreductase activity
MID02_RS18065	COG2385	sporulation resulting in formation of a cellular spore
MID02_RS18070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MID02_RS18080	COG4836	Membrane
MID02_RS18150	COG0698	ribose 5-phosphate isomerase
MID02_RS18155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MID02_RS18165	COG0009	L-threonylcarbamoyladenylate synthase
MID02_RS18170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MID02_RS18190	COG2890	protein-(glutamine-N5) methyltransferase activity
MID02_RS18195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MID02_RS18200	COG0346	lactoylglutathione lyase activity
MID02_RS18205	COG0789	Transcriptional regulator
MID02_RS18210	COG0679	Auxin Efflux Carrier
MID02_RS18215	COG0281	malic enzyme
MID02_RS18230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MID02_RS18240	COG1494	fructose-1,6-bisphosphatase
MID02_RS18245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MID02_RS18255	COG0191	fructose-bisphosphate aldolase activity
MID02_RS18260	COG2204	response regulator
MID02_RS18265	COG4821	SIS domain
MID02_RS18280	COG0247	lactate metabolic process
MID02_RS18280	COG2181	nitrate reductase activity
MID02_RS18285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MID02_RS18300	COG1132	(ABC) transporter
MID02_RS18305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MID02_RS18315	COG2181	nitrate reductase activity
MID02_RS18320	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MID02_RS18325	COG1140	nitrate reductase beta subunit
MID02_RS18330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MID02_RS18335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MID02_RS18345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MID02_RS18350	COG2223	nitrite transmembrane transporter activity
MID02_RS18360	COG4506	Protein conserved in bacteria
MID02_RS18365	COG0457	Tetratricopeptide repeat
MID02_RS18400	COG0010	Belongs to the arginase family
MID02_RS18405	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MID02_RS18410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MID02_RS18425	COG1994	Peptidase M50
MID02_RS18430	COG1942	4-Oxalocrotonate Tautomerase
MID02_RS18435	COG1846	Transcriptional regulator
MID02_RS18440	COG0531	amino acid
MID02_RS18445	COG3465	dGTPase activity
MID02_RS18450	COG1078	dGTPase activity
MID02_RS18465	COG1695	Transcriptional regulator
MID02_RS18485	COG0583	DNA-binding transcription factor activity
MID02_RS18490	COG2855	membrane
MID02_RS18495	COG0280	phosphate acetyltransferase
MID02_RS18505	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS18510	COG0436	Aminotransferase
MID02_RS18540	COG2814	Major facilitator Superfamily
MID02_RS18545	COG2814	Major facilitator Superfamily
MID02_RS18550	COG0833	amino acid
MID02_RS18555	COG4187	Peptidase family M20/M25/M40
MID02_RS18560	COG1012	belongs to the aldehyde dehydrogenase family
MID02_RS18565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MID02_RS18575	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MID02_RS18580	COG1091	dTDP-4-dehydrorhamnose reductase activity
MID02_RS18585	COG1088	dTDP-glucose 4,6-dehydratase activity
MID02_RS18590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MID02_RS18595	COG3980	spore coat polysaccharide biosynthesis protein
MID02_RS18600	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
MID02_RS18605	COG2089	acid synthase
MID02_RS18610	COG0456	acetyltransferase
MID02_RS18615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MID02_RS18620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MID02_RS18625	COG0463	Glycosyl transferase, family 2
MID02_RS18635	COG2363	Small membrane protein
MID02_RS18640	COG2233	PERMEase
MID02_RS18655	COG1216	Glycosyl transferase, family 2
MID02_RS18670	COG1695	Transcriptional regulator
MID02_RS18675	COG0351	phosphomethylpyrimidine kinase
MID02_RS18685	COG1621	beta-fructofuranosidase activity
MID02_RS18690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID02_RS18690	COG1263	PTS System
MID02_RS18695	COG3711	transcriptional antiterminator
MID02_RS18705	COG1404	Belongs to the peptidase S8 family
MID02_RS18710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MID02_RS18715	COG0778	Nitroreductase
MID02_RS18720	COG0772	Belongs to the SEDS family
MID02_RS18725	COG0454	-acetyltransferase
MID02_RS18745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MID02_RS18750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MID02_RS18755	COG2261	transglycosylase associated protein
MID02_RS18760	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MID02_RS18765	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MID02_RS18770	COG2246	polysaccharide biosynthetic process
MID02_RS18775	COG1309	transcriptional regulator
MID02_RS18795	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MID02_RS18800	COG2837	iron assimilation
MID02_RS18820	COG0583	DNA-binding transcription factor activity
MID02_RS18830	COG1346	cytolysis
MID02_RS18835	COG4895	conserved protein (DUF2196)
MID02_RS18840	COG0789	Transcriptional regulator
MID02_RS18845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MID02_RS18850	COG0346	lactoylglutathione lyase activity
MID02_RS18855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MID02_RS18860	COG1404	Belongs to the peptidase S8 family
MID02_RS18865	COG1442	glycosyl transferase family 8
MID02_RS18870	COG2357	RelA SpoT domain protein
MID02_RS18875	COG1575	Belongs to the MenA family. Type 1 subfamily
MID02_RS18890	COG1696	Membrane protein involved in D-alanine export
MID02_RS18900	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MID02_RS18905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MID02_RS18910	COG1486	melibiose metabolic process
MID02_RS18915	COG1447	Phosphotransferase system cellobiose-specific component IIA
MID02_RS18920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MID02_RS18925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MID02_RS18930	COG3711	transcriptional antiterminator
MID02_RS18930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID02_RS18940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID02_RS18945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID02_RS18955	COG0640	Transcriptional regulator
MID02_RS18960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MID02_RS18965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MID02_RS18970	COG1447	Phosphotransferase system cellobiose-specific component IIA
MID02_RS18975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MID02_RS18980	COG2723	6-phospho-beta-galactosidase activity
MID02_RS18985	COG1940	carbohydrate kinase activity
MID02_RS18990	COG1482	cell wall glycoprotein biosynthetic process
MID02_RS19000	COG0753	catalase activity
MID02_RS19005	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MID02_RS19010	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MID02_RS19015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MID02_RS19020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MID02_RS19025	COG4988	ABC transporter
MID02_RS19030	COG1294	oxidase, subunit
MID02_RS19035	COG1271	oxidase subunit
MID02_RS19040	COG3493	citrate carrier protein
MID02_RS19045	COG0726	polysaccharide deacetylase
MID02_RS19050	COG3842	ATPase activity
MID02_RS19055	COG2508	Transcriptional regulator
MID02_RS19060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MID02_RS19070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MID02_RS19085	COG4894	glucomannan catabolic process
MID02_RS19090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MID02_RS19095	COG0500	methyltransferase
MID02_RS19100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MID02_RS19115	COG0753	catalase activity
MID02_RS19115	COG0693	protein deglycase activity
MID02_RS19120	COG2851	Citrate transporter
MID02_RS19125	COG2273	Hydrolase Family 16
MID02_RS19135	COG2270	Major facilitator Superfamily
MID02_RS19140	COG0513	Belongs to the DEAD box helicase family
MID02_RS19220	COG0697	spore germination
MID02_RS19225	COG0589	response to stress
MID02_RS19230	COG2723	6-phospho-beta-galactosidase activity
MID02_RS19250	COG3507	Belongs to the glycosyl hydrolase 43 family
MID02_RS19275	COG0010	Belongs to the arginase family
MID02_RS19280	COG0833	amino acid
MID02_RS19285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MID02_RS19290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MID02_RS19300	COG2390	Transcriptional regulator
MID02_RS19305	COG0561	phosphatase activity
MID02_RS19335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MID02_RS19340	COG5294	Protein conserved in bacteria
MID02_RS19345	COG0577	efflux transmembrane transporter activity
MID02_RS19350	COG1136	(ABC) transporter
MID02_RS19355	COG2205	protein histidine kinase activity
MID02_RS19360	COG0745	RESPONSE REGULATOR receiver
MID02_RS19365	COG2205	protein histidine kinase activity
MID02_RS19370	COG0745	RESPONSE REGULATOR receiver
MID02_RS19395	COG0745	RESPONSE REGULATOR receiver
MID02_RS19425	COG1082	Xylose isomerase domain protein TIM barrel
MID02_RS19435	COG2814	Major facilitator Superfamily
MID02_RS19465	COG1349	DNA-binding transcription factor activity
MID02_RS19470	COG0667	Aldo Keto reductase
MID02_RS19475	COG2814	Major facilitator Superfamily
MID02_RS19490	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS19495	COG2197	response regulator
MID02_RS19500	COG4585	Histidine kinase
MID02_RS19505	COG3239	Fatty acid desaturase
MID02_RS19510	COG1309	transcriptional regulator
MID02_RS19515	COG1012	belongs to the aldehyde dehydrogenase family
MID02_RS19520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MID02_RS19530	COG0640	Transcriptional regulator
MID02_RS19535	COG2814	Major facilitator Superfamily
MID02_RS19540	COG1714	RDD family
MID02_RS19550	COG0450	alkyl hydroperoxide reductase
MID02_RS19555	COG3634	alkyl hydroperoxide reductase activity
MID02_RS19560	COG1113	amino acid transport
MID02_RS19570	COG2080	2 iron, 2 sulfur cluster binding
MID02_RS19585	COG2068	MobA-Related Protein
MID02_RS19590	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MID02_RS19605	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MID02_RS19615	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MID02_RS19640	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MID02_RS19645	COG0667	Aldo Keto reductase
MID02_RS19650	COG0456	acetyltransferase
MID02_RS19655	COG0457	Tetratricopeptide repeat
MID02_RS19660	COG0010	Belongs to the arginase family
MID02_RS19665	COG0833	amino acid
MID02_RS19670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MID02_RS19675	COG3829	transcription factor binding
MID02_RS19685	COG0488	(ABC) transporter
MID02_RS19700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MID02_RS19705	COG5002	protein histidine kinase activity
MID02_RS19715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MID02_RS19720	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MID02_RS19725	COG4853	Protein conserved in bacteria
MID02_RS19730	COG4863	YycH protein
MID02_RS19735	COG5002	protein histidine kinase activity
MID02_RS19740	COG0745	RESPONSE REGULATOR receiver
MID02_RS19770	COG0346	lactoylglutathione lyase activity
MID02_RS19775	COG0305	Participates in initiation and elongation during chromosome replication
MID02_RS19790	COG3093	addiction module antidote protein HigA
MID02_RS19795	COG0297	glycogen (starch) synthase activity
MID02_RS19805	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MID02_RS19810	COG0438	transferase activity, transferring glycosyl groups
MID02_RS19830	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MID02_RS19835	COG4241	membrane
MID02_RS19845	COG5577	PFAM Coat F domain
MID02_RS19850	COG1733	regulation of RNA biosynthetic process
MID02_RS19860	COG0697	spore germination
MID02_RS19865	COG1621	beta-fructofuranosidase activity
MID02_RS19870	COG1621	beta-fructofuranosidase activity
MID02_RS19875	COG1802	Transcriptional regulator
MID02_RS19880	COG2318	DinB family
MID02_RS19885	COG2211	Major facilitator Superfamily
MID02_RS19895	COG0778	Nitroreductase
MID02_RS19905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MID02_RS19910	COG1846	Transcriptional regulator
MID02_RS19925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MID02_RS19930	COG0583	DNA-binding transcription factor activity
MID02_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
MID02_RS19940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MID02_RS19945	COG0697	spore germination
MID02_RS19965	COG1331	Highly conserved protein containing a thioredoxin domain
MID02_RS19970	COG1266	CAAX protease self-immunity
MID02_RS19975	COG2814	Major facilitator Superfamily
MID02_RS19975	COG0477	Major facilitator Superfamily
MID02_RS19980	COG0346	lactoylglutathione lyase activity
MID02_RS19985	COG1609	Transcriptional regulator
MID02_RS19990	COG0708	Exodeoxyribonuclease III
MID02_RS19995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MID02_RS20000	COG2169	Transcriptional regulator
MID02_RS20010	COG0629	single-stranded DNA binding
MID02_RS20020	COG0012	GTP binding
MID02_RS20025	COG0243	molybdopterin cofactor binding
MID02_RS20030	COG4481	Protein conserved in bacteria
MID02_RS20035	COG3949	Membrane
MID02_RS20050	COG1475	DNA binding
MID02_RS20055	COG1192	Involved in chromosome partitioning
MID02_RS20080	COG1847	R3H domain protein
MID02_RS20085	COG0706	membrane insertase activity